NPSR1_HUMAN Loading...

Neuropeptide S receptor

G-protein coupled receptor for neuropeptide S (NPS)^1,2,3. Receptor activation by NPS initiates a G(q)/GNAQ-dependent phospholipase C-activating signaling pathway, resulting in Ca(2+) mobilization from intracellular stores and increased intracellular Ca(2+) levels^4,5,6,7,8,9. In addition to this pathway, NPS binding to its receptor activates cAMP/PKA signal transduction¹⁰. Finally, both pathways converge to activate ERK1/ERK2 phosphorylation and signaling cascade¹¹. Inhibits cell growth in response to NPS binding¹².

AlphaFold DB , UniProt , Accession Q6W5P4, Species HUMAN (Homo sapiens, Human), Gene NPSR1, Length 371 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	36.2	Very low	34.5	Very low	233 Å²	233	153.8 Å²	153.8	100%	1.148	86%	0.863	S	S	*	*				0	151.6	0	-83.6	-176.2	176.6	0	0	108.7
2	P	55.1	Low	34.3	Very low	120 Å²	120	148.8 Å²	148.8	78%	0.779	85%	0.846	S	S	*	*			cis	-109.5	153.3	18	36.2	-22.8	0	0	0	112.4
3	A	33.7	Very low	33.8	Very low	78 Å²	78	146.5 Å²	146.5	65%	0.645	84%	0.844	S	S	*	*				68.7	102.4	50.9	0	0	0	0	0	113.2
4	N	36.7	Very low	33.8	Very low	165 Å²	165	141.6 Å²	141.6	88%	0.882	84%	0.842	S	S	*	*			trans	-151.3	119.9	140.2	-129.7	10.1	0	0	0	110.2
5	F	31.6	Very low	33.6	Very low	202 Å²	202	142.3 Å²	142.3	89%	0.886	85%	0.848	S	S	*	*			trans	-80.1	134.4	169.6	-89.3	-102.1	0	0	0	108.1
6	T	36.4	Very low	33.7	Very low	142 Å²	142	138.3 Å²	138.3	87%	0.871	85%	0.845	S	S	*	*			trans	-114.5	111.9	163.7	15.1	0	0	0	0	107.9
7	E	28.9	Very low	33.6	Very low	197 Å²	197	140.4 Å²	140.4	92%	0.921	84%	0.843	S	S	*	*			trans	-63.9	137.8	164.7	-70.2	173.8	140.1	0	0	109.8
8	G	34	Very low	33.6	Very low	76 Å²	76	139.1 Å²	139.1	78%	0.784	84%	0.836	S	S	*	*			trans	-152	98.3	171.9	0	0	0	0	0	108.6
9	S	28.9	Very low	33.9	Very low	126 Å²	126	140.9 Å²	140.9	88%	0.881	84%	0.84	S	S	*	*			trans	-57.2	146.7	-178.9	-77.5	0	0	0	0	113.8
10	F	26.1	Very low	34	Very low	196 Å²	196	142.3 Å²	142.3	86%	0.86	84%	0.843	S	S	*	*			trans	-46.6	133.3	161.2	-91.6	-114.6	0	0	0	112.5
11	D	32.2	Very low	34.2	Very low	157 Å²	157	141.2 Å²	141.2	84%	0.84	84%	0.843	S	S	*	*			trans	-145.4	120.7	143.9	-101.5	-27.8	0	0	0	112.1
12	S	31.3	Very low	34.3	Very low	94 Å²	94	135.6 Å²	135.6	66%	0.657	83%	0.826	S	S	*	*			trans	32.5	119.3	149	70.2	0	0	0	0	123.1
13	S	27.7	Very low	33.9	Very low	118 Å²	118	135.8 Å²	135.8	83%	0.825	83%	0.828	S	S	*	*				47.8	119.3	128.7	63.5	0	0	0	0	121.3
14	G	34.8	Very low	34.2	Very low	79 Å²	79	139 Å²	139	81%	0.814	84%	0.839	S	S	*	*			trans	177.1	79.6	162.3	0	0	0	0	0	113.4
15	T	30	Very low	34.7	Very low	152 Å²	152	135 Å²	135	93%	0.933	83%	0.829	S	S	*	*			trans	-67.4	137.2	178.5	-32.8	0	0	0	0	112.3
16	G	35.6	Very low	35.7	Very low	77 Å²	77	130.8 Å²	130.8	79%	0.794	82%	0.823	S	S	*	*			trans	169	73.9	171.2	0	0	0	0	0	113.3
17	Q	32.5	Very low	36.4	Very low	175 Å²	175	129.2 Å²	129.2	82%	0.818	81%	0.814	S	S	*	*			trans	-81.9	141.7	-175	-87.4	-177.2	-24.9	0	0	114.4
18	T	32.7	Very low	37.6	Very low	117 Å²	117	127.7 Å²	127.7	72%	0.718	81%	0.807	S	S	*	*			trans	57	130.2	132.2	63.5	0	0	0	0	122.4
19	L	38.9	Very low	38.5	Very low	173 Å²	173	128.5 Å²	128.5	91%	0.906	80%	0.797	S	S	*	*				-162	101	123.3	-100.7	155.9	0	0	0	108
20	D	36.1	Very low	39.8	Very low	168 Å²	168	126.9 Å²	126.9	90%	0.898	78%	0.781	S	S	*	*			trans	-123.9	127.9	171.3	-118.8	-19	0	0	0	109.8
21	S	39	Very low	41.5	Very low	121 Å²	121	121.3 Å²	121.3	85%	0.846	76%	0.763	S	S	*	*			trans	-84.4	121.2	-168.2	-37.6	0	0	0	0	110.7
22	S	38.8	Very low	42.6	Very low	114 Å²	114	120.7 Å²	120.7	80%	0.797	75%	0.753	S	S	*	*			trans	-104.8	148.8	170.3	-85.8	0	0	0	0	112.2
23	P	45.9	Very low	44.2	Very low	124 Å²	124	119.1 Å²	119.1	81%	0.805	74%	0.74	S	S	*	*			trans	-88.9	137.4	-162.9	34.6	-33	0	0	0	113.2
24	V	39.8	Very low	46	Very low	146 Å²	146	119.3 Å²	119.3	89%	0.885	73%	0.727	S	S	*	*			trans	-79.3	118.1	173.3	175.2	0	0	0	0	108.9
25	A	48.4	Very low	47.5	Very low	82 Å²	82	118.8 Å²	118.8	68%	0.678	71%	0.709	S	S	*	*			trans	-135.1	92.3	172.3	0	0	0	0	0	110.6	T27	A25-T27 PolarHBondContact O-N 3.27Å
26	C	51	Low	48.9	Very low	112 Å²	112	113.7 Å²	113.7	76%	0.757	68%	0.677	S	S	*	*			trans	29.9	65.9	147.5	-54.4	0	0	0	0	120
27	T	51.9	Low	50	Low	110 Å²	110	116.1 Å²	116.1	68%	0.675	67%	0.668	S	S	*	*			trans	-97.8	-13.7	157.8	-30.3	0	0	0	0	112.3	A25 T29 T31	A25-T27 PolarHBondContact O-N 3.27Å; T27-T29 PolarHBondContact O-N 3.22Å; T27-T31 PolarHBondContact O-OG1 2.98Å
28	E	54.2	Low	51.5	Low	165 Å²	165	109.9 Å²	109.9	77%	0.771	65%	0.651	S	S	*	*	H	α-helix	trans	-68.6	-30.7	-172.9	-72.7	-176	164.5	0	0	114.1	V30 F32	E28-V30 PolarHBondContact O-N 3.02Å; E28-F32 WeakPolarHBondContact O-CB 3.49Å; E28-F32 PolarHBondContact O-N 3.28Å
29	T	53.2	Low	53.2	Low	93 Å²	93	111.3 Å²	111.3	57%	0.571	65%	0.647	S	S	*	*	H	α-helix	trans	-65.9	-42.7	-172.5	-43.1	0	0	0	0	111.9	T27 F32 T33	T27-T29 PolarHBondContact O-N 3.22Å; T29-F32 PolarHBondContact O-N 3.48Å; T29-T33 PolarHBondContact O-N 3.38Å; T29-T33 PolarHBondContact O-OG1 3.49Å
30	V	55.7	Low	54.6	Low	92 Å²	92	109.3 Å²	109.3	56%	0.558	63%	0.633	S	S	*	*	H	α-helix	trans	-67.7	-46.8	-178.9	-178.6	0	0	0	0	110.9	E28 F32 T33 E34	E28-V30 PolarHBondContact O-N 3.02Å; V30-F32 VanDerWaalsContact C-N 3.34Å; V30-F32 PolarHBondContact O-N 3.02Å; V30-T33 WeakPolarHBondContact CA-OG1 3.47Å; V30-T33 PolarHBondContact O-N 3.47Å; V30-T33 PolarHBondContact O-OG1 3.28Å; V30-E34 WeakPolarHBondContact O-CG 3.29Å; V30-E34 PolarHBondContact O-N 3.34Å
31	T	61.1	Low	56.1	Low	78 Å²	78	108.2 Å²	108.2	48%	0.479	62%	0.616	S	S	.	*	H	α-helix	trans	-64.9	-39.1	177.8	-37.5	0	0	0	0	111.5	T27 V35	T27-T31 PolarHBondContact O-OG1 2.98Å; T31-V35 HydrophobicContact CG2-CG2 4.47Å; T31-V35 VanDerWaalsContact O-CB 3.32Å; T31-V35 WeakPolarHBondContact O-CB 3.38Å; T31-V35 WeakPolarHBondContact O-CG2 3.34Å; T31-V35 PolarHBondContact O-N 2.77Å
32	F	56.1	Low	57.6	Low	144 Å²	144	104.2 Å²	104.2	63%	0.632	59%	0.594	S	S	*	*	H	α-helix	trans	-66.3	-44.2	177	-175.5	-95.7	0	0	0	111.4	E28 T29 V30 V35 V36	E28-F32 WeakPolarHBondContact O-CB 3.49Å; E28-F32 PolarHBondContact O-N 3.28Å; T29-F32 PolarHBondContact O-N 3.48Å; V30-F32 VanDerWaalsContact C-N 3.34Å; V30-F32 PolarHBondContact O-N 3.02Å; F32-V35 PolarHBondContact O-N 2.83Å; F32-V36 HydrophobicContact CD1-CG2 3.93Å; F32-V36 HydrophobicContact CD2-CG2 4.39Å; F32-V36 HydrophobicContact CE1-CG2 3.58Å; F32-V36 HydrophobicContact CE2-CG2 4.08Å; F32-V36 HydrophobicContact CG-CG2 4.33Å; F32-V36 HydrophobicContact CZ-CG2 3.66Å; F32-V36 WeakPolarHBondContact O-CB 3.04Å; F32-V36 VanDerWaalsContact O-CG2 3.23Å; F32-V36 WeakPolarHBondContact O-CG2 3.44Å; F32-V36 PolarHBondContact O-N 3.03Å
33	T	64.8	Low	59.3	Low	61 Å²	61	102.9 Å²	102.9	37%	0.374	59%	0.585	S	S	.	*	H	α-helix	trans	-61.7	-45.4	175.4	41.8	0	0	0	0	111.7	T29 V30 V35 V36 E37	T29-T33 PolarHBondContact O-N 3.38Å; T29-T33 PolarHBondContact O-OG1 3.49Å; V30-T33 WeakPolarHBondContact CA-OG1 3.47Å; V30-T33 PolarHBondContact O-N 3.47Å; V30-T33 PolarHBondContact O-OG1 3.28Å; T33-V35 PolarHBondContact O-N 3.02Å; T33-V36 PolarHBondContact O-N 3.17Å; T33-E37 WeakPolarHBondContact O-CB 3.38Å; T33-E37 VanDerWaalsContact O-CG 3.24Å; T33-E37 WeakPolarHBondContact O-CG 3.49Å; T33-E37 PolarHBondContact O-N 3.22Å
34	E	66.4	Low	60.5	Low	122 Å²	122	99.2 Å²	99.2	57%	0.57	56%	0.556	S	S	*	*	H	α-helix	trans	-64.7	-38	177.9	-73.6	-179.4	172	0	0	112.7	V30 G38	V30-E34 WeakPolarHBondContact O-CG 3.29Å; V30-E34 PolarHBondContact O-N 3.34Å; E34-G38 PolarHBondContact O-N 3.34Å
35	V	66.1	Low	62.1	Low	69 Å²	69	98 Å²	98	42%	0.418	54%	0.537	S	S	.	.	H	α-helix	trans	-71	-38.6	177.6	170.9	0	0	0	0	111.4	T31 F32 T33 K39	T31-V35 HydrophobicContact CG2-CG2 4.47Å; T31-V35 VanDerWaalsContact O-CB 3.32Å; T31-V35 WeakPolarHBondContact O-CB 3.38Å; T31-V35 WeakPolarHBondContact O-CG2 3.34Å; T31-V35 PolarHBondContact O-N 2.77Å; F32-V35 PolarHBondContact O-N 2.83Å; T33-V35 PolarHBondContact O-N 3.02Å; V35-K39 HydrophobicContact CG1-CD 4.3Å; V35-K39 WeakPolarHBondContact O-CB 3.46Å; V35-K39 VanDerWaalsContact O-CG 3.29Å; V35-K39 WeakPolarHBondContact O-CG 3.29Å; V35-K39 PolarHBondContact O-N 3.31Å
36	V	59	Low	63.3	Low	45 Å²	45	102 Å²	102	27%	0.273	54%	0.535	S	S	.	.	H	α-helix	trans	-68.8	-49.5	175.2	171.8	0	0	0	0	110	F32 T33 G38 K39 E40	F32-V36 HydrophobicContact CD1-CG2 3.93Å; F32-V36 HydrophobicContact CD2-CG2 4.39Å; F32-V36 HydrophobicContact CE1-CG2 3.58Å; F32-V36 HydrophobicContact CE2-CG2 4.08Å; F32-V36 HydrophobicContact CG-CG2 4.33Å; F32-V36 HydrophobicContact CZ-CG2 3.66Å; F32-V36 WeakPolarHBondContact O-CB 3.04Å; F32-V36 VanDerWaalsContact O-CG2 3.23Å; F32-V36 WeakPolarHBondContact O-CG2 3.44Å; F32-V36 PolarHBondContact O-N 3.03Å; T33-V36 PolarHBondContact O-N 3.17Å; V36-G38 VanDerWaalsContact C-N 3.3Å; V36-G38 PolarHBondContact O-N 3.08Å; V36-K39 PolarHBondContact O-N 2.99Å; V36-K39 VanDerWaalsContact O-N 3.14Å; V36-E40 HydrophobicContact CG1-CG 4.27Å; V36-E40 WeakPolarHBondContact O-CB 3.33Å; V36-E40 WeakPolarHBondContact O-CG 3.43Å; V36-E40 PolarHBondContact O-N 3.23Å
37	E	59.6	Low	64.6	Low	127 Å²	127	99.5 Å²	99.5	59%	0.593	52%	0.519	S	S	*	.	H	α-helix	trans	-56.1	-45.1	174.4	-75.9	178.5	178.2	0	0	110.5	T33 K39 E40 W41	T33-E37 WeakPolarHBondContact O-CB 3.38Å; T33-E37 VanDerWaalsContact O-CG 3.24Å; T33-E37 WeakPolarHBondContact O-CG 3.49Å; T33-E37 PolarHBondContact O-N 3.22Å; E37-K39 PolarHBondContact O-N 2.97Å; E37-E40 PolarHBondContact O-N 3.36Å; E37-W41 WeakPolarHBondContact O-CB 3.28Å; E37-W41 PolarHBondContact O-N 3.44Å
38	G	63.1	Low	65.8	Low	45 Å²	45	97.1 Å²	97.1	46%	0.464	50%	0.5	S	S	.	.	H	α-helix	trans	-63.9	-37.9	176.7	0	0	0	0	0	113.9	E34 V36 G42	E34-G38 PolarHBondContact O-N 3.34Å; V36-G38 VanDerWaalsContact C-N 3.3Å; V36-G38 PolarHBondContact O-N 3.08Å; G38-G42 PolarHBondContact O-N 3.13Å
39	K	68.8	Low	67.2	Low	147 Å²	147	92.8 Å²	92.8	64%	0.639	48%	0.478	S	S	*	.	H	α-helix	trans	-70.8	-43	175	-79	174.4	-176.9	166.8	0	112.1	V35 V36 E37 G42 S43	V35-K39 HydrophobicContact CG1-CD 4.3Å; V35-K39 WeakPolarHBondContact O-CB 3.46Å; V35-K39 VanDerWaalsContact O-CG 3.29Å; V35-K39 WeakPolarHBondContact O-CG 3.29Å; V35-K39 PolarHBondContact O-N 3.31Å; V36-K39 PolarHBondContact O-N 2.99Å; V36-K39 VanDerWaalsContact O-N 3.14Å; E37-K39 PolarHBondContact O-N 2.97Å; K39-G42 PolarHBondContact O-N 3.24Å; K39-S43 VanDerWaalsContact O-CB 3.32Å; K39-S43 WeakPolarHBondContact O-CB 3.41Å; K39-S43 PolarHBondContact O-N 3.03Å
40	E	68.8	Low	68.7	Low	130 Å²	130	90.9 Å²	90.9	61%	0.607	47%	0.467	S	S	*	.	H	α-helix	trans	-62.1	-47.7	175.4	-74.2	-175.7	168.2	0	0	109.9	V36 E37 G42 S43 F44	V36-E40 HydrophobicContact CG1-CG 4.27Å; V36-E40 WeakPolarHBondContact O-CB 3.33Å; V36-E40 WeakPolarHBondContact O-CG 3.43Å; V36-E40 PolarHBondContact O-N 3.23Å; E37-E40 PolarHBondContact O-N 3.36Å; E40-G42 VanDerWaalsContact C-N 3.35Å; E40-G42 PolarHBondContact O-N 3.19Å; E40-S43 PolarHBondContact O-N 3.08Å; E40-F44 WeakPolarHBondContact O-CB 3.4Å; E40-F44 PolarHBondContact O-N 3.32Å
41	W	66.3	Low	70.2	Confident	146 Å²	146	91.6 Å²	91.6	55%	0.553	46%	0.464	S	S	*	.	H	α-helix	trans	-63.5	-38.2	177.1	-146.9	81.2	0	0	0	112.2	E37 Y45	E37-W41 WeakPolarHBondContact O-CB 3.28Å; E37-W41 PolarHBondContact O-N 3.44Å; W41-Y45 WeakPolarHBondContact O-CB 3.36Å; W41-Y45 PolarHBondContact O-N 3.43Å
42	G	70.9	Confident	71.5	Confident	37 Å²	37	88.8 Å²	88.8	38%	0.381	45%	0.445	S	S	.	.	H	α-helix	trans	-68.2	-47.1	175.6	0	0	0	0	0	113.6	G38 K39 E40 F44 Y45 Y46	G38-G42 PolarHBondContact O-N 3.13Å; K39-G42 PolarHBondContact O-N 3.24Å; E40-G42 VanDerWaalsContact C-N 3.35Å; E40-G42 PolarHBondContact O-N 3.19Å; G42-F44 VanDerWaalsContact C-N 3.33Å; G42-Y45 PolarHBondContact O-N 3.37Å; G42-Y46 WeakPolarHBondContact O-CB 3.46Å; G42-Y46 PolarHBondContact O-N 3.34Å
43	S	73.5	Confident	73.1	Confident	86 Å²	86	83.7 Å²	83.7	60%	0.601	43%	0.425	S	S	*	.	H	α-helix	trans	-61.6	-44.3	174.7	-179.4	0	0	0	0	111.1	K39 E40 Y46 S47	K39-S43 VanDerWaalsContact O-CB 3.32Å; K39-S43 WeakPolarHBondContact O-CB 3.41Å; K39-S43 PolarHBondContact O-N 3.03Å; E40-S43 PolarHBondContact O-N 3.08Å; S43-Y46 PolarHBondContact O-N 2.96Å; S43-S47 WeakPolarHBondContact O-CB 3.3Å; S43-S47 PolarHBondContact O-N 3.33Å
44	F	71.8	Confident	74.4	Confident	47 Å²	47	84.9 Å²	84.9	21%	0.206	43%	0.428	C	S	.	.	H	α-helix	trans	-57.9	-54.6	174.3	172.2	-97.5	0	0	0	111.4	E40 G42 Y46 S47 F48 F309 Y310	E40-F44 WeakPolarHBondContact O-CB 3.4Å; E40-F44 PolarHBondContact O-N 3.32Å; G42-F44 VanDerWaalsContact C-N 3.33Å; F44-Y46 VanDerWaalsContact C-N 3.27Å; F44-Y46 PolarHBondContact O-N 2.87Å; F44-S47 PolarHBondContact O-N 3.01Å; F44-F48 HydrophobicContact CD1-CD2 4.36Å; F44-F48 AromaticContact CD2-CD2 3.75Å; F44-F48 HydrophobicContact CD2-CD2 3.75Å; F44-F48 AromaticContact CD2-CE2 3.66Å; F44-F48 HydrophobicContact CD2-CE2 3.66Å; F44-F48 HydrophobicContact CE1-CD2 4.03Å; F44-F48 HydrophobicContact CE1-CE2 4.42Å; F44-F48 AromaticContact CE2-CD2 3.36Å; F44-F48 HydrophobicContact CE2-CD2 3.36Å; F44-F48 AromaticContact CE2-CE2 3.02Å; F44-F48 HydrophobicContact CE2-CE2 3.02Å; F44-F48 AromaticContact CE2-CZ 3.95Å; F44-F48 HydrophobicContact CE2-CZ 3.95Å; F44-F48 HydrophobicContact CG-CD2 4.21Å; F44-F48 AromaticContact CZ-CD2 3.49Å; F44-F48 HydrophobicContact CZ-CD2 3.49Å; F44-F48 VanDerWaalsContact CZ-CD2 3.49Å; F44-F48 AromaticContact CZ-CE2 3.47Å; F44-F48 HydrophobicContact CZ-CE2 3.47Å; F44-F48 VanDerWaalsContact CZ-CE2 3.47Å; F44-F48 HydrophobicContact CZ-CG 4.28Å; F44-F48 HydrophobicContact CZ-CZ 4.19Å; F44-F48 WeakPolarHBondContact O-CD2 3.25Å; F44-F48 PolarHBondContact O-N 3.27Å; F44-F309 HydrophobicContact CE1-CD1 4.4Å; F44-F309 HydrophobicContact CE1-CE1 4.3Å; F44-Y310 AromaticContact CE2-CE1 3.54Å; F44-Y310 HydrophobicContact CE2-CE1 3.54Å; F44-Y310 AromaticContact CE2-CZ 3.52Å; F44-Y310 WeakPolarHBondContact CE2-OH 3.38Å; F44-Y310 HydrophobicContact CZ-CD1 4.21Å; F44-Y310 AromaticContact CZ-CE1 3.29Å; F44-Y310 HydrophobicContact CZ-CE1 3.29Å; F44-Y310 HydrophobicContact CZ-CE2 4.21Å; F44-Y310 AromaticContact CZ-CZ 3.27Å; F44-Y310 WeakPolarHBondContact CZ-OH 3.33Å
45	Y	72.8	Confident	75.7	Confident	121 Å²	121	81.9 Å²	81.9	48%	0.475	42%	0.418	S	S	.	.	H	α-helix	trans	-56.4	-40.7	177.7	179.6	-99.8	0	0	0	112.1	W41 G42 K49 F309	W41-Y45 WeakPolarHBondContact O-CB 3.36Å; W41-Y45 PolarHBondContact O-N 3.43Å; G42-Y45 PolarHBondContact O-N 3.37Å; Y45-K49 WeakPolarHBondContact O-CB 3.47Å; Y45-K49 PolarHBondContact O-N 2.95Å; Y45-F309 HydrophobicContact CD2-CZ 4.21Å; Y45-F309 HydrophobicContact CE2-CZ 4.36Å
46	Y	75	Confident	77.1	Confident	164 Å²	164	78.8 Å²	78.8	64%	0.643	40%	0.399	S	S	*	.	H	α-helix	trans	-67.3	-43.6	177.8	-170.9	-89.9	0	0	0	113.1	G42 S43 F44 K49 T50	G42-Y46 WeakPolarHBondContact O-CB 3.46Å; G42-Y46 PolarHBondContact O-N 3.34Å; S43-Y46 PolarHBondContact O-N 2.96Å; F44-Y46 VanDerWaalsContact C-N 3.27Å; F44-Y46 PolarHBondContact O-N 2.87Å; Y46-K49 PolarHBondContact O-N 3.43Å; Y46-T50 PolarHBondContact O-N 2.98Å; Y46-T50 PolarHBondContact O-OG1 3.47Å
47	S	78	Confident	78.8	Confident	60 Å²	60	82.2 Å²	82.2	42%	0.42	41%	0.407	S	S	.	.	H	α-helix	trans	-58.8	-48.8	174.9	-173.8	0	0	0	0	110.8	S43 F44 K49 T50 E51	S43-S47 WeakPolarHBondContact O-CB 3.3Å; S43-S47 PolarHBondContact O-N 3.33Å; F44-S47 PolarHBondContact O-N 3.01Å; S47-K49 PolarHBondContact O-N 3.34Å; S47-T50 WeakPolarHBondContact O-CB 3.23Å; S47-T50 PolarHBondContact O-N 2.9Å; S47-T50 VanDerWaalsContact O-N 3.08Å; S47-E51 PolarHBondContact O-N 3.07Å
48	F	77.7	Confident	80.6	Confident	60 Å²	60	79.6 Å²	79.6	26%	0.263	40%	0.399	S	S	.	.	H	α-helix	trans	-61.4	-41.4	177.5	-90.2	-85.8	0	0	0	113.5	F44 T50 E51 Q52 Y310	F44-F48 HydrophobicContact CD1-CD2 4.36Å; F44-F48 AromaticContact CD2-CD2 3.75Å; F44-F48 HydrophobicContact CD2-CD2 3.75Å; F44-F48 AromaticContact CD2-CE2 3.66Å; F44-F48 HydrophobicContact CD2-CE2 3.66Å; F44-F48 HydrophobicContact CE1-CD2 4.03Å; F44-F48 HydrophobicContact CE1-CE2 4.42Å; F44-F48 AromaticContact CE2-CD2 3.36Å; F44-F48 HydrophobicContact CE2-CD2 3.36Å; F44-F48 AromaticContact CE2-CE2 3.02Å; F44-F48 HydrophobicContact CE2-CE2 3.02Å; F44-F48 AromaticContact CE2-CZ 3.95Å; F44-F48 HydrophobicContact CE2-CZ 3.95Å; F44-F48 HydrophobicContact CG-CD2 4.21Å; F44-F48 AromaticContact CZ-CD2 3.49Å; F44-F48 HydrophobicContact CZ-CD2 3.49Å; F44-F48 VanDerWaalsContact CZ-CD2 3.49Å; F44-F48 AromaticContact CZ-CE2 3.47Å; F44-F48 HydrophobicContact CZ-CE2 3.47Å; F44-F48 VanDerWaalsContact CZ-CE2 3.47Å; F44-F48 HydrophobicContact CZ-CG 4.28Å; F44-F48 HydrophobicContact CZ-CZ 4.19Å; F44-F48 WeakPolarHBondContact O-CD2 3.25Å; F44-F48 PolarHBondContact O-N 3.27Å; F48-T50 VanDerWaalsContact C-N 3.26Å; F48-T50 PolarHBondContact O-N 3.27Å; F48-E51 PolarHBondContact O-N 3.38Å; F48-Q52 WeakPolarHBondContact O-CB 3.28Å; F48-Q52 PolarHBondContact O-N 2.72Å; F48-Y310 HydrophobicContact CD1-CD1 4.41Å; F48-Y310 AromaticContact CE1-CD1 3.56Å; F48-Y310 HydrophobicContact CE1-CD1 3.56Å; F48-Y310 AromaticContact CE1-CE1 3.74Å; F48-Y310 HydrophobicContact CE1-CE1 3.74Å; F48-Y310 HydrophobicContact CE2-CD1 4.38Å; F48-Y310 AromaticContact CE2-CE1 3.71Å; F48-Y310 HydrophobicContact CE2-CE1 3.71Å; F48-Y310 AromaticContact CZ-CD1 3.58Å; F48-Y310 HydrophobicContact CZ-CD1 3.58Å; F48-Y310 AromaticContact CZ-CE1 3.24Å; F48-Y310 HydrophobicContact CZ-CE1 3.24Å
49	K	81.7	Confident	82.2	Confident	75 Å²	75	78.3 Å²	78.3	33%	0.326	38%	0.382	S	S	.	.	H	α-helix	trans	-59.9	-39	174.7	-172.7	177.9	179.3	-179.9	0	111.5	Y45 Y46 S47 L53 R109	Y45-K49 WeakPolarHBondContact O-CB 3.47Å; Y45-K49 PolarHBondContact O-N 2.95Å; Y46-K49 PolarHBondContact O-N 3.43Å; S47-K49 PolarHBondContact O-N 3.34Å; K49-L53 WeakPolarHBondContact O-CB 3.47Å; K49-L53 PolarHBondContact O-N 2.9Å; K49-R109 WeakPolarHBondContact CE-O 3.17Å; K49-R109 PolarHBondContact NZ-O 3.41Å
50	T	86	Confident	83.5	Confident	53 Å²	53	72.8 Å²	72.8	33%	0.325	36%	0.358	S	S	.	.	H	α-helix	trans	-67.6	-49.1	178.9	-56.3	0	0	0	0	111.4	Y46 S47 F48 Q52 L53 I54	Y46-T50 PolarHBondContact O-N 2.98Å; Y46-T50 PolarHBondContact O-OG1 3.47Å; S47-T50 WeakPolarHBondContact O-CB 3.23Å; S47-T50 PolarHBondContact O-N 2.9Å; S47-T50 VanDerWaalsContact O-N 3.08Å; F48-T50 VanDerWaalsContact C-N 3.26Å; F48-T50 PolarHBondContact O-N 3.27Å; T50-Q52 VanDerWaalsContact C-N 3.32Å; T50-Q52 PolarHBondContact O-N 2.83Å; T50-L53 PolarHBondContact O-N 3.38Å; T50-I54 HydrophobicContact CG2-CD1 4.05Å; T50-I54 WeakPolarHBondContact O-CG1 3.4Å; T50-I54 PolarHBondContact O-N 3.05Å
51	E	87.2	Confident	84.9	Confident	107 Å²	107	70.3 Å²	70.3	50%	0.5	35%	0.351	S	S	.	.	H	α-helix	trans	-60.7	-40.6	177.8	-67.6	-56.9	149.4	0	0	112.6	S47 F48 I54 T55	S47-E51 PolarHBondContact O-N 3.07Å; F48-E51 PolarHBondContact O-N 3.38Å; E51-I54 PolarHBondContact O-N 3.5Å; E51-T55 WeakPolarHBondContact O-CB 3.41Å; E51-T55 PolarHBondContact O-N 2.94Å; E51-T55 PolarHBondContact O-OG1 2.97Å
52	Q	87.7	Confident	86.4	Confident	19 Å²	19	69 Å²	69	9%	0.089	35%	0.35	C	S	.	.	H	α-helix	trans	-65.6	-41.7	176.2	-171.1	168.9	29.3	0	0	111.7	F48 T50 T55 L56 R109 V313	F48-Q52 WeakPolarHBondContact O-CB 3.28Å; F48-Q52 PolarHBondContact O-N 2.72Å; T50-Q52 VanDerWaalsContact C-N 3.32Å; T50-Q52 PolarHBondContact O-N 2.83Å; Q52-T55 PolarHBondContact O-N 3.01Å; Q52-L56 HydrophobicContact CG-CD1 4.16Å; Q52-L56 WeakPolarHBondContact O-CB 3.38Å; Q52-L56 WeakPolarHBondContact O-CG 3.42Å; Q52-L56 PolarHBondContact O-N 3.17Å; Q52-R109 VanDerWaalsContact CD-CZ 3.44Å; Q52-V313 HydrophobicContact CB-CG1 4.49Å; Q52-V313 HydrophobicContact CG-CG1 4.4Å
53	L	90.6	Very high	87.6	Confident	37 Å²	37	67.2 Å²	67.2	19%	0.194	33%	0.332	C	S	.	.	H	α-helix	trans	-63.2	-42.9	176.9	-173.6	63.8	0	0	0	111.5	K49 T50 L56 W57 I106 R109	K49-L53 WeakPolarHBondContact O-CB 3.47Å; K49-L53 PolarHBondContact O-N 2.9Å; T50-L53 PolarHBondContact O-N 3.38Å; L53-L56 PolarHBondContact O-N 3.31Å; L53-W57 VanDerWaalsContact O-CD1 3.22Å; L53-W57 PolarHBondContact O-N 3.41Å; L53-I106 HydrophobicContact CD1-CG2 4.09Å; L53-R109 HydrophobicContact CD1-CB 4.41Å
54	I	92.6	Very high	88.8	Confident	86 Å²	86	65.2 Å²	65.2	44%	0.441	31%	0.314	S	S	.	.	H	α-helix	trans	-60	-48.6	175	-67.2	166.3	0	0	0	110.1	T50 E51 L56 W57 V58	T50-I54 HydrophobicContact CG2-CD1 4.05Å; T50-I54 WeakPolarHBondContact O-CG1 3.4Å; T50-I54 PolarHBondContact O-N 3.05Å; E51-I54 PolarHBondContact O-N 3.5Å; I54-L56 VanDerWaalsContact C-N 3.33Å; I54-L56 PolarHBondContact O-N 2.84Å; I54-W57 PolarHBondContact O-N 3.43Å; I54-V58 WeakPolarHBondContact O-CG2 3.22Å; I54-V58 PolarHBondContact O-N 3.5Å
55	T	93.4	Very high	90	Very high	58 Å²	58	67 Å²	67	36%	0.356	33%	0.328	S	S	.	.	H	α-helix	trans	-58.2	-44.7	179.1	-60.3	0	0	0	0	111.7	E51 Q52 V58 L59	E51-T55 WeakPolarHBondContact O-CB 3.41Å; E51-T55 PolarHBondContact O-N 2.94Å; E51-T55 PolarHBondContact O-OG1 2.97Å; Q52-T55 PolarHBondContact O-N 3.01Å; T55-V58 PolarHBondContact O-N 2.82Å; T55-L59 HydrophobicContact CG2-CD1 4.08Å; T55-L59 WeakPolarHBondContact O-CG 3.34Å; T55-L59 PolarHBondContact O-N 3.12Å
56	L	94.1	Very high	91.2	Very high	4 Å²	4	62 Å²	62	2%	0.021	31%	0.314	C	S	.	.	H	α-helix	trans	-65.9	-40	178.4	-72.9	167.6	0	0	0	112.6	Q52 L53 I54 L59 F60 I102 D105 I106	Q52-L56 HydrophobicContact CG-CD1 4.16Å; Q52-L56 WeakPolarHBondContact O-CB 3.38Å; Q52-L56 WeakPolarHBondContact O-CG 3.42Å; Q52-L56 PolarHBondContact O-N 3.17Å; L53-L56 PolarHBondContact O-N 3.31Å; I54-L56 VanDerWaalsContact C-N 3.33Å; I54-L56 PolarHBondContact O-N 2.84Å; L56-L59 PolarHBondContact O-N 3.2Å; L56-F60 VanDerWaalsContact O-CB 3.29Å; L56-F60 WeakPolarHBondContact O-CB 3.29Å; L56-F60 PolarHBondContact O-N 3.04Å; L56-I102 HydrophobicContact CD2-CG2 4.39Å; L56-D105 VanDerWaalsContact CD1-OD2 3.28Å; L56-D105 WeakPolarHBondContact CD1-OD2 3.34Å; L56-I106 HydrophobicContact CB-CD1 4.21Å; L56-I106 HydrophobicContact CB-CG1 3.81Å
57	W	95.9	Very high	92.2	Very high	117 Å²	117	54.3 Å²	54.3	44%	0.443	28%	0.283	S	S	.	.	H	α-helix	trans	-62.5	-42.2	174.2	-86.9	115.7	0	0	0	112.3	L53 I54 F60 V61 I106	L53-W57 VanDerWaalsContact O-CD1 3.22Å; L53-W57 PolarHBondContact O-N 3.41Å; I54-W57 PolarHBondContact O-N 3.43Å; W57-F60 AromaticContact CE3-CD1 3.86Å; W57-F60 HydrophobicContact CE3-CD1 3.86Å; W57-F60 AromaticContact CZ3-CD1 3.78Å; W57-F60 HydrophobicContact CZ3-CD1 3.78Å; W57-F60 HydrophobicContact CZ3-CE1 4.01Å; W57-F60 PolarHBondContact O-N 3.15Å; W57-V61 WeakPolarHBondContact O-CG2 3.44Å; W57-V61 PolarHBondContact O-N 3.5Å; W57-I106 HydrophobicContact CD2-CD1 3.91Å; W57-I106 HydrophobicContact CD2-CG2 4.15Å; W57-I106 HydrophobicContact CE3-CD1 4.02Å; W57-I106 HydrophobicContact CG-CD1 4.24Å; W57-I106 HydrophobicContact CH2-CG2 4.08Å; W57-I106 HydrophobicContact CZ2-CG2 3.38Å; W57-I106 HydrophobicContact CZ3-CD1 4.45Å
58	V	96.4	Very high	93.2	Very high	72 Å²	72	54.4 Å²	54.4	44%	0.436	28%	0.284	S	S	.	.	H	α-helix	trans	-59.9	-51.8	174.1	172	0	0	0	0	109.8	I54 T55 F60 V61 F62	I54-V58 WeakPolarHBondContact O-CG2 3.22Å; I54-V58 PolarHBondContact O-N 3.5Å; T55-V58 PolarHBondContact O-N 2.82Å; V58-F60 VanDerWaalsContact C-N 3.3Å; V58-F60 PolarHBondContact O-N 2.99Å; V58-V61 PolarHBondContact O-N 2.95Å; V58-F62 HydrophobicContact CG1-CD2 3.65Å; V58-F62 HydrophobicContact CG1-CE2 3.75Å; V58-F62 VanDerWaalsContact O-CD2 3.3Å; V58-F62 WeakPolarHBondContact O-CD2 3.27Å; V58-F62 PolarHBondContact O-N 3.25Å
59	L	96.4	Very high	94	Very high	18 Å²	18	55.3 Å²	55.3	9%	0.094	29%	0.294	C	S	.	.	H	α-helix	trans	-59.5	-39.5	178.3	-71.2	173.7	0	0	0	112.4	T55 L56 T63 N317 A320 L321 A324	T55-L59 HydrophobicContact CG2-CD1 4.08Å; T55-L59 WeakPolarHBondContact O-CG 3.34Å; T55-L59 PolarHBondContact O-N 3.12Å; L56-L59 PolarHBondContact O-N 3.2Å; L59-T63 WeakPolarHBondContact O-CB 3.45Å; L59-T63 PolarHBondContact O-N 3.32Å; L59-T63 PolarHBondContact O-OG1 3Å; L59-N317 HydrophobicContact CD1-CB 4.31Å; L59-A320 HydrophobicContact CB-CB 4.48Å; L59-A320 HydrophobicContact CD1-CB 3.85Å; L59-L321 HydrophobicContact CD2-CB 4.3Å; L59-L321 HydrophobicContact CD2-CD1 4.01Å; L59-A324 HydrophobicContact CD2-CB 3.94Å
60	F	97.6	Very high	94.7	Very high	32 Å²	32	51.9 Å²	51.9	14%	0.14	28%	0.279	C	S	.	.	H	α-helix	trans	-60	-52.8	176	174.9	-109.7	0	0	0	111.5	L56 W57 V58 F62 T63 I64 G98 I102 L103 I106	L56-F60 VanDerWaalsContact O-CB 3.29Å; L56-F60 WeakPolarHBondContact O-CB 3.29Å; L56-F60 PolarHBondContact O-N 3.04Å; W57-F60 AromaticContact CE3-CD1 3.86Å; W57-F60 HydrophobicContact CE3-CD1 3.86Å; W57-F60 AromaticContact CZ3-CD1 3.78Å; W57-F60 HydrophobicContact CZ3-CD1 3.78Å; W57-F60 HydrophobicContact CZ3-CE1 4.01Å; W57-F60 PolarHBondContact O-N 3.15Å; V58-F60 VanDerWaalsContact C-N 3.3Å; V58-F60 PolarHBondContact O-N 2.99Å; F60-F62 PolarHBondContact O-N 3.33Å; F60-T63 PolarHBondContact O-N 3.36Å; F60-I64 HydrophobicContact CD2-CG1 3.91Å; F60-I64 HydrophobicContact CE1-CG1 4.49Å; F60-I64 HydrophobicContact CE2-CD1 4.09Å; F60-I64 HydrophobicContact CE2-CG1 3.51Å; F60-I64 HydrophobicContact CZ-CG1 3.85Å; F60-I64 WeakPolarHBondContact O-CG1 3.28Å; F60-I64 PolarHBondContact O-N 2.99Å; F60-G98 WeakPolarHBondContact CD2-O 3.3Å; F60-G98 WeakPolarHBondContact CE2-O 3.5Å; F60-I102 HydrophobicContact CB-CG2 3.76Å; F60-I102 HydrophobicContact CD2-CB 4.33Å; F60-I102 HydrophobicContact CD2-CG2 4.39Å; F60-L103 HydrophobicContact CD2-CB 4.22Å; F60-L103 HydrophobicContact CE1-CD1 4.48Å; F60-L103 HydrophobicContact CE2-CB 3.76Å; F60-L103 HydrophobicContact CE2-CD1 4.29Å; F60-L103 HydrophobicContact CE2-CG 4.41Å; F60-L103 HydrophobicContact CZ-CB 4.35Å; F60-L103 HydrophobicContact CZ-CD1 4.09Å; F60-L103 HydrophobicContact CZ-CD2 4.46Å; F60-I106 HydrophobicContact CB-CD1 3.84Å; F60-I106 HydrophobicContact CG-CD1 4.23Å
61	V	97.5	Very high	95.2	Very high	77 Å²	77	51.5 Å²	51.5	47%	0.467	28%	0.275	S	S	.	.	H	α-helix	trans	-60.9	-47.1	-179.8	173	0	0	0	0	110.7	W57 V58 T63 I64 V65	W57-V61 WeakPolarHBondContact O-CG2 3.44Å; W57-V61 PolarHBondContact O-N 3.5Å; V58-V61 PolarHBondContact O-N 2.95Å; V61-T63 VanDerWaalsContact C-N 3.35Å; V61-T63 PolarHBondContact O-N 3.23Å; V61-I64 PolarHBondContact O-N 3.48Å; V61-V65 HydrophobicContact CG1-CG2 4.1Å; V61-V65 VanDerWaalsContact O-CB 3.25Å; V61-V65 WeakPolarHBondContact O-CB 3.49Å; V61-V65 VanDerWaalsContact O-CG2 3.29Å; V61-V65 WeakPolarHBondContact O-CG2 3.43Å; V61-V65 PolarHBondContact O-N 3.31Å
62	F	97	Very high	95.6	Very high	119 Å²	119	52.3 Å²	52.3	52%	0.522	28%	0.277	S	S	.	.	H	α-helix	trans	-61.2	-42.3	177.3	-88.4	-78.4	0	0	0	112.4	V58 F60 G66 A324	V58-F62 HydrophobicContact CG1-CD2 3.65Å; V58-F62 HydrophobicContact CG1-CE2 3.75Å; V58-F62 VanDerWaalsContact O-CD2 3.3Å; V58-F62 WeakPolarHBondContact O-CD2 3.27Å; V58-F62 PolarHBondContact O-N 3.25Å; F60-F62 PolarHBondContact O-N 3.33Å; F62-G66 VanDerWaalsContact O-CA 3.28Å; F62-G66 WeakPolarHBondContact O-CA 3.36Å; F62-G66 PolarHBondContact O-N 3.22Å; F62-A324 HydrophobicContact CB-CB 4.4Å
63	T	97.6	Very high	95.8	Very high	0 Å²	0	53 Å²	53	0%	0	28%	0.284	C	S	.	.	H	α-helix	trans	-65.3	-49.3	179.6	-59.2	0	0	0	0	111.1	L59 F60 V61 N67 D94 I102 A324	L59-T63 WeakPolarHBondContact O-CB 3.45Å; L59-T63 PolarHBondContact O-N 3.32Å; L59-T63 PolarHBondContact O-OG1 3Å; F60-T63 PolarHBondContact O-N 3.36Å; V61-T63 VanDerWaalsContact C-N 3.35Å; V61-T63 PolarHBondContact O-N 3.23Å; T63-N67 VanDerWaalsContact O-CB 3.27Å; T63-N67 WeakPolarHBondContact O-CB 3.44Å; T63-N67 PolarHBondContact O-N 2.9Å; T63-N67 VanDerWaalsContact O-N 3.08Å; T63-N67 PolarHBondContact O-ND2 3.31Å; T63-D94 VanDerWaalsContact CG2-O 3.29Å; T63-D94 WeakPolarHBondContact CG2-O 3.4Å; T63-I102 HydrophobicContact CG2-CD1 4.31Å; T63-A324 WeakPolarHBondContact OG1-CA 3.46Å; T63-A324 WeakPolarHBondContact OG1-CB 3.29Å
64	I	97.7	Very high	95.9	Very high	44 Å²	44	51.6 Å²	51.6	23%	0.226	28%	0.277	C	S	.	.	H	α-helix	trans	-69.1	-52.1	-177.6	-66.2	-60.4	0	0	0	111.3	F60 V61 S68 S95 L99	F60-I64 HydrophobicContact CD2-CG1 3.91Å; F60-I64 HydrophobicContact CE1-CG1 4.49Å; F60-I64 HydrophobicContact CE2-CD1 4.09Å; F60-I64 HydrophobicContact CE2-CG1 3.51Å; F60-I64 HydrophobicContact CZ-CG1 3.85Å; F60-I64 WeakPolarHBondContact O-CG1 3.28Å; F60-I64 PolarHBondContact O-N 2.99Å; V61-I64 PolarHBondContact O-N 3.48Å; I64-S68 WeakPolarHBondContact O-CB 3.48Å; I64-S68 PolarHBondContact O-N 2.83Å; I64-S68 PolarHBondContact O-OG 2.93Å; I64-S95 WeakPolarHBondContact CD1-O 3.41Å; I64-L99 HydrophobicContact CD1-CB 4.47Å
65	V	97.4	Very high	95.8	Very high	85 Å²	85	55.6 Å²	55.6	52%	0.515	29%	0.287	S	S	.	.	H	α-helix	trans	-66.2	-46.8	-177.9	176.4	0	0	0	0	110.3	V61 S68 V69	V61-V65 HydrophobicContact CG1-CG2 4.1Å; V61-V65 VanDerWaalsContact O-CB 3.25Å; V61-V65 WeakPolarHBondContact O-CB 3.49Å; V61-V65 VanDerWaalsContact O-CG2 3.29Å; V61-V65 WeakPolarHBondContact O-CG2 3.43Å; V61-V65 PolarHBondContact O-N 3.31Å; V65-S68 PolarHBondContact O-N 3.36Å; V65-V69 WeakPolarHBondContact O-CG2 3.44Å; V65-V69 PolarHBondContact O-N 2.84Å
66	G	97.1	Very high	95.7	Very high	16 Å²	16	61 Å²	61	17%	0.165	30%	0.301	C	S	.	.	H	α-helix	trans	-59.8	-51.3	-179	0	0	0	0	0	112.1	F62 S68 V69 V70	F62-G66 VanDerWaalsContact O-CA 3.28Å; F62-G66 WeakPolarHBondContact O-CA 3.36Å; F62-G66 PolarHBondContact O-N 3.22Å; G66-S68 VanDerWaalsContact C-N 3.35Å; G66-S68 PolarHBondContact O-N 3.24Å; G66-V69 PolarHBondContact O-N 3.4Å; G66-V70 WeakPolarHBondContact O-CG2 3.24Å; G66-V70 PolarHBondContact O-N 3.45Å
67	N	97.7	Very high	95.4	Very high	2 Å²	2	64.5 Å²	64.5	1%	0.011	31%	0.314	C	S	.	.	H	α-helix	trans	-69.2	-33.3	-179.8	-72.8	-64.2	0	0	0	112.1	T63 V69 V70 L71 A91 D94 S95 S323 P327	T63-N67 VanDerWaalsContact O-CB 3.27Å; T63-N67 WeakPolarHBondContact O-CB 3.44Å; T63-N67 PolarHBondContact O-N 2.9Å; T63-N67 VanDerWaalsContact O-N 3.08Å; T63-N67 PolarHBondContact O-ND2 3.31Å; N67-V69 VanDerWaalsContact C-N 3.34Å; N67-V69 PolarHBondContact O-N 2.95Å; N67-V70 WeakPolarHBondContact O-CB 3.43Å; N67-V70 PolarHBondContact O-N 3.4Å; N67-L71 VanDerWaalsContact O-CG 3.28Å; N67-L71 WeakPolarHBondContact O-CG 3.23Å; N67-L71 PolarHBondContact O-N 3.08Å; N67-A91 HydrophobicContact CB-CB 4.33Å; N67-D94 WeakPolarHBondContact ND2-CB 3.45Å; N67-S95 VanDerWaalsContact CB-OG 3.23Å; N67-S95 WeakPolarHBondContact CB-OG 2.72Å; N67-S323 PolarHBondContact ND2-O 2.77Å; N67-P327 HydrophobicContact CB-CG 4.4Å; N67-P327 WeakPolarHBondContact OD1-CG 3.42Å
68	S	97.2	Very high	94.7	Very high	61 Å²	61	69.4 Å²	69.4	43%	0.427	34%	0.338	S	S	.	.	H	α-helix	trans	-60.6	-41.9	171.8	-61.5	0	0	0	0	112.2	I64 V65 G66 L71 F72	I64-S68 WeakPolarHBondContact O-CB 3.48Å; I64-S68 PolarHBondContact O-N 2.83Å; I64-S68 PolarHBondContact O-OG 2.93Å; V65-S68 PolarHBondContact O-N 3.36Å; G66-S68 VanDerWaalsContact C-N 3.35Å; G66-S68 PolarHBondContact O-N 3.24Å; S68-L71 PolarHBondContact O-N 3.18Å; S68-F72 WeakPolarHBondContact O-CB 3.21Å; S68-F72 PolarHBondContact O-N 3.36Å
69	V	96	Very high	94.1	Very high	79 Å²	79	75 Å²	75	48%	0.479	36%	0.356	S	S	.	.	H	α-helix	trans	-64.1	-40.8	174.2	170	0	0	0	0	111.3	V65 G66 N67 F72 S73	V65-V69 WeakPolarHBondContact O-CG2 3.44Å; V65-V69 PolarHBondContact O-N 2.84Å; G66-V69 PolarHBondContact O-N 3.4Å; N67-V69 VanDerWaalsContact C-N 3.34Å; N67-V69 PolarHBondContact O-N 2.95Å; V69-F72 PolarHBondContact O-N 3.05Å; V69-S73 WeakPolarHBondContact O-CB 3.41Å; V69-S73 PolarHBondContact O-N 3.2Å
70	V	95.9	Very high	93.5	Very high	3 Å²	3	81.1 Å²	81.1	2%	0.018	38%	0.382	C	S	.	.	H	α-helix	trans	-61.8	-46.1	175.1	176	0	0	0	0	111.1	G66 N67 S73 T74 V87 A91 P327 Y330	G66-V70 WeakPolarHBondContact O-CG2 3.24Å; G66-V70 PolarHBondContact O-N 3.45Å; N67-V70 WeakPolarHBondContact O-CB 3.43Å; N67-V70 PolarHBondContact O-N 3.4Å; V70-S73 PolarHBondContact O-N 3.4Å; V70-T74 HydrophobicContact CG1-CG2 4.35Å; V70-T74 WeakPolarHBondContact O-CB 3.35Å; V70-T74 WeakPolarHBondContact O-CG2 3.36Å; V70-T74 PolarHBondContact O-N 3.01Å; V70-T74 PolarHBondContact O-OG1 3.09Å; V70-V87 HydrophobicContact CG1-CG1 3.55Å; V70-A91 HydrophobicContact CB-CB 4.13Å; V70-A91 HydrophobicContact CG1-CB 3.78Å; V70-P327 HydrophobicContact CG2-CB 3.85Å; V70-P327 HydrophobicContact CG2-CG 4.19Å; V70-Y330 HydrophobicContact CB-CD1 4.29Å; V70-Y330 HydrophobicContact CG1-CD1 4.05Å; V70-Y330 HydrophobicContact CG1-CD2 4.47Å; V70-Y330 HydrophobicContact CG1-CE1 4.3Å; V70-Y330 HydrophobicContact CG1-CG 4.1Å; V70-Y330 HydrophobicContact CG2-CD1 3.72Å; V70-Y330 HydrophobicContact CG2-CE1 4.45Å; V70-Y330 HydrophobicContact CG2-CG 4.1Å
71	L	96.3	Very high	92.9	Very high	45 Å²	45	82.1 Å²	82.1	24%	0.236	39%	0.394	C	S	.	.	H	α-helix	trans	-62.2	-47.1	178	-68.8	173.3	0	0	0	111.3	N67 S68 S73 T74 W75 T88 A91 I92	N67-L71 VanDerWaalsContact O-CG 3.28Å; N67-L71 WeakPolarHBondContact O-CG 3.23Å; N67-L71 PolarHBondContact O-N 3.08Å; S68-L71 PolarHBondContact O-N 3.18Å; L71-S73 PolarHBondContact O-N 3Å; L71-T74 PolarHBondContact O-N 3.03Å; L71-T74 PolarHBondContact O-OG1 3.24Å; L71-T74 VanDerWaalsContact O-OG1 3.08Å; L71-W75 VanDerWaalsContact O-CB 3.25Å; L71-W75 WeakPolarHBondContact O-CB 3.37Å; L71-W75 PolarHBondContact O-N 3.18Å; L71-T88 HydrophobicContact CD2-CG2 3.94Å; L71-A91 HydrophobicContact CD2-CB 3.74Å; L71-A91 HydrophobicContact CG-CB 3.93Å; L71-I92 HydrophobicContact CD2-CG1 3.75Å
72	F	95.2	Very high	92.4	Very high	124 Å²	124	80.2 Å²	80.2	54%	0.544	38%	0.378	S	S	.	.	H	α-helix	trans	-60.4	-45.5	175.5	-179	-102	0	0	0	111.9	S68 V69 T74 W75 R76	S68-F72 WeakPolarHBondContact O-CB 3.21Å; S68-F72 PolarHBondContact O-N 3.36Å; V69-F72 PolarHBondContact O-N 3.05Å; F72-T74 PolarHBondContact O-N 3.29Å; F72-W75 HydrophobicContact CD2-CE3 4.18Å; F72-W75 HydrophobicContact CD2-CZ3 4.43Å; F72-W75 HydrophobicContact CE2-CE3 4.29Å; F72-W75 HydrophobicContact CE2-CZ3 4.16Å; F72-W75 PolarHBondContact O-N 2.94Å; F72-R76 HydrophobicContact CE1-CG 4.17Å; F72-R76 HydrophobicContact CE2-CG 4.17Å; F72-R76 HydrophobicContact CZ-CG 3.99Å; F72-R76 VanDerWaalsContact O-CG 3.29Å; F72-R76 WeakPolarHBondContact O-CG 3.37Å; F72-R76 PolarHBondContact O-N 3.42Å; F72-R76 VanDerWaalsContact O-N 3.1Å
73	S	92.4	Very high	92	Very high	34 Å²	34	76 Å²	76	24%	0.238	36%	0.36	C	S	.	.	H	α-helix	trans	-60.4	-46.1	178.1	-178.6	0	0	0	0	111.9	V69 V70 L71 R77 Y330	V69-S73 WeakPolarHBondContact O-CB 3.41Å; V69-S73 PolarHBondContact O-N 3.2Å; V70-S73 PolarHBondContact O-N 3.4Å; L71-S73 PolarHBondContact O-N 3Å; S73-R77 WeakPolarHBondContact O-CG 2.94Å; S73-Y330 PolarHBondContact OG-OH 3.45Å
74	T	92.2	Very high	91.7	Very high	7 Å²	7	76.9 Å²	76.9	4%	0.043	37%	0.366	C	S	.	.	H	α-helix	trans	-71.6	-35	-179.7	55	0	0	0	0	112.3	V70 L71 F72 R77 V87 T88 Y330	V70-T74 HydrophobicContact CG1-CG2 4.35Å; V70-T74 WeakPolarHBondContact O-CB 3.35Å; V70-T74 WeakPolarHBondContact O-CG2 3.36Å; V70-T74 PolarHBondContact O-N 3.01Å; V70-T74 PolarHBondContact O-OG1 3.09Å; L71-T74 PolarHBondContact O-N 3.03Å; L71-T74 PolarHBondContact O-OG1 3.24Å; L71-T74 VanDerWaalsContact O-OG1 3.08Å; F72-T74 PolarHBondContact O-N 3.29Å; T74-R77 WeakPolarHBondContact O-CB 3.48Å; T74-R77 PolarHBondContact O-N 3.28Å; T74-V87 HydrophobicContact CG2-CG1 4Å; T74-T88 WeakPolarHBondContact CB-OG1 3.21Å; T74-T88 PolarHBondContact OG1-OG1 2.72Å; T74-T88 VanDerWaalsContact OG1-OG1 3.1Å; T74-Y330 HydrophobicContact CG2-CE2 4.19Å
75	W	91.8	Very high	91.5	Very high	170 Å²	170	77.7 Å²	77.7	64%	0.644	37%	0.368	S	S	*	.	H	α-helix	trans	-63.2	-40.4	175	177	66.4	0	0	0	112.7	L71 F72 R77	L71-W75 VanDerWaalsContact O-CB 3.25Å; L71-W75 WeakPolarHBondContact O-CB 3.37Å; L71-W75 PolarHBondContact O-N 3.18Å; F72-W75 HydrophobicContact CD2-CE3 4.18Å; F72-W75 HydrophobicContact CD2-CZ3 4.43Å; F72-W75 HydrophobicContact CE2-CE3 4.29Å; F72-W75 HydrophobicContact CE2-CZ3 4.16Å; F72-W75 PolarHBondContact O-N 2.94Å; W75-R77 VanDerWaalsContact C-N 3.26Å; W75-R77 PolarHBondContact O-N 3.29Å
76	R	91.1	Very high	91.3	Very high	172 Å²	172	73.8 Å²	73.8	65%	0.649	34%	0.344	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74.8	-6.9	179.9	-64.9	-74.5	-79.6	-170.4	-5.8	114.2	F72 K78	F72-R76 HydrophobicContact CE1-CG 4.17Å; F72-R76 HydrophobicContact CE2-CG 4.17Å; F72-R76 HydrophobicContact CZ-CG 3.99Å; F72-R76 VanDerWaalsContact O-CG 3.29Å; F72-R76 WeakPolarHBondContact O-CG 3.37Å; F72-R76 PolarHBondContact O-N 3.42Å; F72-R76 VanDerWaalsContact O-N 3.1Å; R76-K78 PolarHBondContact O-N 2.97Å
77	R	86.4	Confident	91.2	Very high	77 Å²	77	73.1 Å²	73.1	29%	0.291	34%	0.337	S	S	.	.			trans	-71.7	121	179.2	-67.3	-64.4	-173.1	166.3	0	111.2	S73 T74 W75 K79	S73-R77 WeakPolarHBondContact O-CG 2.94Å; T74-R77 WeakPolarHBondContact O-CB 3.48Å; T74-R77 PolarHBondContact O-N 3.28Å; W75-R77 VanDerWaalsContact C-N 3.26Å; W75-R77 PolarHBondContact O-N 3.29Å; R77-K79 PolarHBondContact O-N 3.44Å
78	K	82.2	Confident	91.1	Very high	221 Å²	221	74.8 Å²	74.8	96%	0.961	35%	0.347	S	S	*	.	S	Bend	trans	-60.1	-42.5	174.3	-66.1	-173.5	178.8	-176.9	0	113.1	R76	R76-K78 PolarHBondContact O-N 2.97Å
79	K	82.9	Confident	91.1	Very high	188 Å²	188	73.4 Å²	73.4	82%	0.817	33%	0.334	S	S	*	.	S	Bend	trans	-107.1	106.8	177.3	-171.8	171.8	-176	170.9	0	109.8	R77	R77-K79 PolarHBondContact O-N 3.44Å
80	K	83.8	Confident	91.1	Very high	147 Å²	147	70 Å²	70	64%	0.639	31%	0.313	S	S	*	.			trans	-78.7	126.7	174	-66	-179.5	-179.4	170.2	0	108.9
81	S	85.4	Confident	91.1	Very high	54 Å²	54	69.9 Å²	69.9	38%	0.378	31%	0.313	S	S	.	.			trans	-102.1	161.7	174	71.7	0	0	0	0	110.5	M83 T84 F85	S81-M83 PolarHBondContact O-N 3.25Å; S81-T84 WeakPolarHBondContact CA-OG1 3.46Å; S81-T84 PolarHBondContact N-OG1 3.43Å; S81-T84 PolarHBondContact O-N 3.15Å; S81-T84 VanDerWaalsContact O-N 3.14Å; S81-T84 PolarHBondContact O-OG1 3.22Å; S81-T84 WeakPolarHBondContact OG-CG2 3.42Å; S81-T84 PolarHBondContact OG-N 3.15Å; S81-T84 VanDerWaalsContact OG-N 3.09Å; S81-T84 PolarHBondContact OG-OG1 3.47Å; S81-T84 VanDerWaalsContact OG-OG1 3.09Å; S81-F85 PolarHBondContact O-N 2.96Å; S81-F85 VanDerWaalsContact O-N 3.11Å
82	R	87.4	Confident	91.2	Very high	37 Å²	37	70.1 Å²	70.1	14%	0.14	31%	0.314	C	S	.	.	H	α-helix	trans	-58.9	-34.1	172.4	-165	171.7	72.2	178	12.6	112.8	F85 F86 D145 G159 A163	R82-F85 WeakPolarHBondContact O-CB 3.38Å; R82-F85 PolarHBondContact O-N 2.92Å; R82-F86 HydrophobicContact CG-CE2 4.22Å; R82-F86 WeakPolarHBondContact O-CD2 3.24Å; R82-F86 PolarHBondContact O-N 3.34Å; R82-D145 WeakPolarHBondContact CD-OD1 3.42Å; R82-D145 VanDerWaalsContact CZ-CG 3.41Å; R82-D145 IonicContact CZ-OD1 2.87Å; R82-D145 IonicContact CZ-OD2 3.32Å; R82-D145 VanDerWaalsContact NE-CG 3.25Å; R82-D145 IonicContact NE-OD1 2.89Å; R82-D145 PolarHBondContact NE-OD1 3.39Å; R82-D145 IonicContact NE-OD2 2.85Å; R82-D145 PolarHBondContact NE-OD2 3.37Å; R82-D145 IonicContact NH1-OD1 3.19Å; R82-D145 PolarHBondContact NH1-OD1 3.45Å; R82-D145 VanDerWaalsContact NH2-CG 3.29Å; R82-D145 PolarHBondContact NH2-O 3.2Å; R82-D145 VanDerWaalsContact NH2-O 3.15Å; R82-D145 IonicContact NH2-OD1 3.55Å; R82-D145 PolarHBondContact NH2-OD1 2.93Å; R82-D145 VanDerWaalsContact NH2-OD1 3.15Å; R82-D145 IonicContact NH2-OD2 3.53Å; R82-D145 PolarHBondContact NH2-OD2 3.4Å; R82-G159 WeakPolarHBondContact CD-O 3.46Å; R82-A163 HydrophobicContact CG-CB 3.93Å
83	M	88.2	Confident	91.3	Very high	29 Å²	29	64.2 Å²	64.2	14%	0.143	29%	0.288	C	S	.	.	H	α-helix	trans	-63.9	-48.1	174.3	-179.7	-171.1	-177.6	0	0	111.3	S81 F85 F86 V87 A272 Y275	S81-M83 PolarHBondContact O-N 3.25Å; M83-F85 PolarHBondContact O-N 2.94Å; M83-F86 PolarHBondContact O-N 2.87Å; M83-V87 HydrophobicContact CG-CG2 4.3Å; M83-V87 VanDerWaalsContact O-CG2 3.24Å; M83-V87 WeakPolarHBondContact O-CG2 3.32Å; M83-V87 PolarHBondContact O-N 2.89Å; M83-A272 HydrophobicContact CB-CB 4.26Å; M83-A272 HydrophobicContact CE-CB 4.33Å; M83-A272 HydrophobicContact CG-CB 4.06Å; M83-A272 HydrophobicContact SD-CB 3.51Å; M83-A272 VanDerWaalsContact SD-CB 3.51Å; M83-Y275 HydrophobicContact CE-CD1 3.43Å; M83-Y275 VanDerWaalsContact CE-CD1 3.43Å; M83-Y275 HydrophobicContact CE-CD2 3.89Å; M83-Y275 HydrophobicContact CE-CE1 4.15Å; M83-Y275 HydrophobicContact CE-CG 3.25Å
84	T	90.9	Very high	91.5	Very high	20 Å²	20	62.6 Å²	62.6	12%	0.123	28%	0.276	C	S	.	.	H	α-helix	trans	-61.9	-28.1	178.7	48	0	0	0	0	112.2	S81 T88	S81-T84 WeakPolarHBondContact CA-OG1 3.46Å; S81-T84 PolarHBondContact N-OG1 3.43Å; S81-T84 PolarHBondContact O-N 3.15Å; S81-T84 VanDerWaalsContact O-N 3.14Å; S81-T84 PolarHBondContact O-OG1 3.22Å; S81-T84 WeakPolarHBondContact OG-CG2 3.42Å; S81-T84 PolarHBondContact OG-N 3.15Å; S81-T84 VanDerWaalsContact OG-N 3.09Å; S81-T84 PolarHBondContact OG-OG1 3.47Å; S81-T84 VanDerWaalsContact OG-OG1 3.09Å; T84-T88 WeakPolarHBondContact O-CB 3.48Å; T84-T88 PolarHBondContact O-N 3.46Å; T84-T88 PolarHBondContact O-OG1 3.38Å
85	F	93.3	Very high	91.8	Very high	60 Å²	60	63.2 Å²	63.2	26%	0.263	28%	0.281	S	S	.	.	H	α-helix	trans	-64	-50.3	173.4	175.4	-107.5	0	0	0	112.4	S81 R82 M83 V87 T88 Q89 A163 R164 I167	S81-F85 PolarHBondContact O-N 2.96Å; S81-F85 VanDerWaalsContact O-N 3.11Å; R82-F85 WeakPolarHBondContact O-CB 3.38Å; R82-F85 PolarHBondContact O-N 2.92Å; M83-F85 PolarHBondContact O-N 2.94Å; F85-V87 VanDerWaalsContact C-N 3.34Å; F85-V87 PolarHBondContact O-N 3.36Å; F85-T88 PolarHBondContact O-N 2.85Å; F85-Q89 HydrophobicContact CE1-CG 4.48Å; F85-Q89 HydrophobicContact CE2-CG 4.34Å; F85-Q89 HydrophobicContact CZ-CG 4.23Å; F85-Q89 WeakPolarHBondContact O-CG 3.36Å; F85-Q89 PolarHBondContact O-N 2.8Å; F85-A163 HydrophobicContact CD1-CB 4.26Å; F85-A163 HydrophobicContact CE1-CB 4.32Å; F85-R164 HydrophobicContact CE1-CG 4.4Å; F85-R164 HydrophobicContact CZ-CG 4.06Å; F85-I167 HydrophobicContact CD1-CG1 4.5Å; F85-I167 HydrophobicContact CE1-CB 4.25Å; F85-I167 HydrophobicContact CE1-CG1 3.58Å; F85-I167 HydrophobicContact CZ-CB 4.31Å; F85-I167 HydrophobicContact CZ-CG1 4.06Å; F85-I167 HydrophobicContact CZ-CG2 4.46Å
86	F	94.4	Very high	92.1	Very high	3 Å²	3	60 Å²	60	1%	0.013	27%	0.272	C	S	.	.	H	α-helix	trans	-62.4	-40.4	174.9	-76.9	-76.1	0	0	0	112.4	R82 M83 T88 Q89 L90 L142 D145 A163 I167	R82-F86 HydrophobicContact CG-CE2 4.22Å; R82-F86 WeakPolarHBondContact O-CD2 3.24Å; R82-F86 PolarHBondContact O-N 3.34Å; M83-F86 PolarHBondContact O-N 2.87Å; F86-T88 VanDerWaalsContact C-N 3.33Å; F86-T88 PolarHBondContact O-N 3.28Å; F86-Q89 PolarHBondContact O-N 3.24Å; F86-L90 WeakPolarHBondContact O-CB 3.29Å; F86-L90 PolarHBondContact O-N 2.76Å; F86-L142 HydrophobicContact CB-CD1 4.04Å; F86-L142 HydrophobicContact CD1-CB 4.08Å; F86-L142 HydrophobicContact CD2-CD1 4.12Å; F86-L142 HydrophobicContact CE1-CB 4.5Å; F86-L142 HydrophobicContact CG-CB 4.36Å; F86-L142 HydrophobicContact CG-CD1 3.99Å; F86-D145 HydrophobicContact CE2-CB 3.6Å; F86-D145 VanDerWaalsContact CE2-CG 3.48Å; F86-D145 HydrophobicContact CZ-CB 3.68Å; F86-A163 HydrophobicContact CE2-CB 3.78Å; F86-A163 HydrophobicContact CZ-CB 3.9Å; F86-I167 HydrophobicContact CD1-CD1 3.78Å; F86-I167 HydrophobicContact CD1-CG1 4.35Å; F86-I167 HydrophobicContact CE1-CD1 3.64Å; F86-I167 HydrophobicContact CE1-CG1 3.96Å
87	V	94.3	Very high	92.4	Very high	3 Å²	3	52.3 Å²	52.3	2%	0.018	24%	0.244	C	C	.	.	H	α-helix	trans	-58.3	-45.3	174.8	173	0	0	0	0	110.9	V70 T74 M83 F85 L90 A91 Y275 Y330	V70-V87 HydrophobicContact CG1-CG1 3.55Å; T74-V87 HydrophobicContact CG2-CG1 4Å; M83-V87 HydrophobicContact CG-CG2 4.3Å; M83-V87 VanDerWaalsContact O-CG2 3.24Å; M83-V87 WeakPolarHBondContact O-CG2 3.32Å; M83-V87 PolarHBondContact O-N 2.89Å; F85-V87 VanDerWaalsContact C-N 3.34Å; F85-V87 PolarHBondContact O-N 3.36Å; V87-L90 PolarHBondContact O-N 3.42Å; V87-A91 WeakPolarHBondContact O-CB 3.46Å; V87-A91 PolarHBondContact O-N 2.84Å; V87-Y275 HydrophobicContact CG2-CE1 3.89Å; V87-Y275 HydrophobicContact CG2-CE2 4.47Å; V87-Y275 WeakPolarHBondContact CG2-OH 3.22Å; V87-Y330 HydrophobicContact CG1-CD2 3.53Å; V87-Y330 HydrophobicContact CG1-CE2 3.79Å; V87-Y330 HydrophobicContact CG1-CG 4.24Å; V87-Y330 HydrophobicContact CG2-CD2 4.29Å
88	T	95.5	Very high	92.9	Very high	37 Å²	37	48.7 Å²	48.7	23%	0.227	23%	0.23	C	C	.	.	H	α-helix	trans	-63.7	-43	177.3	-61.9	0	0	0	0	111.5	L71 T74 T84 F85 F86 L90 A91 I92	L71-T88 HydrophobicContact CD2-CG2 3.94Å; T74-T88 WeakPolarHBondContact CB-OG1 3.21Å; T74-T88 PolarHBondContact OG1-OG1 2.72Å; T74-T88 VanDerWaalsContact OG1-OG1 3.1Å; T84-T88 WeakPolarHBondContact O-CB 3.48Å; T84-T88 PolarHBondContact O-N 3.46Å; T84-T88 PolarHBondContact O-OG1 3.38Å; F85-T88 PolarHBondContact O-N 2.85Å; F86-T88 VanDerWaalsContact C-N 3.33Å; F86-T88 PolarHBondContact O-N 3.28Å; T88-L90 PolarHBondContact O-N 3.17Å; T88-A91 PolarHBondContact O-N 3.42Å; T88-I92 HydrophobicContact CG2-CD1 3.93Å; T88-I92 HydrophobicContact CG2-CG1 4.4Å; T88-I92 VanDerWaalsContact O-CG1 3.26Å; T88-I92 WeakPolarHBondContact O-CG1 3.43Å; T88-I92 PolarHBondContact O-N 3.03Å
89	Q	96.9	Very high	93.6	Very high	32 Å²	32	42.4 Å²	42.4	15%	0.15	21%	0.207	C	C	.	.	H	α-helix	trans	-62.7	-42.4	178	-69.4	-63	-47.1	0	0	112.3	F85 F86 I92 T93 V138 I167	F85-Q89 HydrophobicContact CE1-CG 4.48Å; F85-Q89 HydrophobicContact CE2-CG 4.34Å; F85-Q89 HydrophobicContact CZ-CG 4.23Å; F85-Q89 WeakPolarHBondContact O-CG 3.36Å; F85-Q89 PolarHBondContact O-N 2.8Å; F86-Q89 PolarHBondContact O-N 3.24Å; Q89-I92 PolarHBondContact O-N 2.74Å; Q89-T93 PolarHBondContact O-N 2.64Å; Q89-T93 PolarHBondContact O-OG1 3.22Å; Q89-V138 HydrophobicContact CB-CG1 4.35Å; Q89-I167 HydrophobicContact CB-CD1 4.16Å; Q89-I167 HydrophobicContact CG-CD1 4.08Å; Q89-I167 HydrophobicContact CG-CG1 4.16Å; Q89-I167 HydrophobicContact CG-CG2 3.97Å
90	L	95.9	Very high	94.2	Very high	6 Å²	6	34.5 Å²	34.5	3%	0.031	17%	0.174	C	C	.	.	H	α-helix	trans	-64.5	-47.3	175.8	-171.5	60.4	0	0	0	110.8	F86 V87 T88 I92 T93 D94 V138 L139 I279	F86-L90 WeakPolarHBondContact O-CB 3.29Å; F86-L90 PolarHBondContact O-N 2.76Å; V87-L90 PolarHBondContact O-N 3.42Å; T88-L90 PolarHBondContact O-N 3.17Å; L90-I92 VanDerWaalsContact C-N 3.33Å; L90-I92 PolarHBondContact O-N 2.94Å; L90-T93 WeakPolarHBondContact O-CB 3.42Å; L90-T93 PolarHBondContact O-N 3.34Å; L90-T93 VanDerWaalsContact O-N 3.07Å; L90-D94 WeakPolarHBondContact O-CB 3.29Å; L90-D94 PolarHBondContact O-N 2.99Å; L90-V138 HydrophobicContact CB-CG1 4.23Å; L90-V138 HydrophobicContact CD1-CG1 4.41Å; L90-L139 HydrophobicContact CD1-CD2 4.5Å; L90-L139 HydrophobicContact CD2-CD2 4.19Å; L90-I279 HydrophobicContact CD2-CD1 3.61Å
91	A	97.3	Very high	94.8	Very high	2 Å²	2	29.2 Å²	29.2	2%	0.017	15%	0.153	C	C	.	.	H	α-helix	trans	-62.4	-36	177.8	0	0	0	0	0	113.4	N67 V70 L71 V87 T88 S95	N67-A91 HydrophobicContact CB-CB 4.33Å; V70-A91 HydrophobicContact CB-CB 4.13Å; V70-A91 HydrophobicContact CG1-CB 3.78Å; L71-A91 HydrophobicContact CD2-CB 3.74Å; L71-A91 HydrophobicContact CG-CB 3.93Å; V87-A91 WeakPolarHBondContact O-CB 3.46Å; V87-A91 PolarHBondContact O-N 2.84Å; T88-A91 PolarHBondContact O-N 3.42Å; A91-S95 VanDerWaalsContact O-CB 3.29Å; A91-S95 WeakPolarHBondContact O-CB 3.35Å; A91-S95 PolarHBondContact O-N 2.95Å; A91-S95 PolarHBondContact O-OG 3.26Å; A91-S95 VanDerWaalsContact O-OG 3.08Å
92	I	97.5	Very high	95.3	Very high	50 Å²	50	26.9 Å²	26.9	26%	0.256	14%	0.136	S	C	.	.	H	α-helix	trans	-60.8	-49.9	171.7	-71.7	168.4	0	0	0	109.7	L71 T88 Q89 L90 D94 S95 F96	L71-I92 HydrophobicContact CD2-CG1 3.75Å; T88-I92 HydrophobicContact CG2-CD1 3.93Å; T88-I92 HydrophobicContact CG2-CG1 4.4Å; T88-I92 VanDerWaalsContact O-CG1 3.26Å; T88-I92 WeakPolarHBondContact O-CG1 3.43Å; T88-I92 PolarHBondContact O-N 3.03Å; Q89-I92 PolarHBondContact O-N 2.74Å; L90-I92 VanDerWaalsContact C-N 3.33Å; L90-I92 PolarHBondContact O-N 2.94Å; I92-D94 PolarHBondContact O-N 3.43Å; I92-S95 PolarHBondContact O-N 3.14Å; I92-F96 HydrophobicContact CG2-CD2 3.76Å; I92-F96 HydrophobicContact CG2-CE2 3.66Å; I92-F96 WeakPolarHBondContact O-CD2 3.43Å; I92-F96 PolarHBondContact O-N 3.13Å
93	T	97.3	Very high	95.7	Very high	0 Å²	0	27.1 Å²	27.1	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-62.4	-43	-178.3	-50.7	0	0	0	0	111.6	Q89 L90 F96 T97 L131 A134 W171	Q89-T93 PolarHBondContact O-N 2.64Å; Q89-T93 PolarHBondContact O-OG1 3.22Å; L90-T93 WeakPolarHBondContact O-CB 3.42Å; L90-T93 PolarHBondContact O-N 3.34Å; L90-T93 VanDerWaalsContact O-N 3.07Å; T93-F96 PolarHBondContact O-N 3.42Å; T93-T97 WeakPolarHBondContact O-CB 3.5Å; T93-T97 PolarHBondContact O-N 3.37Å; T93-T97 PolarHBondContact O-OG1 3.39Å; T93-L131 HydrophobicContact CG2-CD2 4.12Å; T93-A134 HydrophobicContact CG2-CB 3.82Å; T93-W171 WeakPolarHBondContact OG1-CZ2 3.15Å
94	D	97.2	Very high	96	Very high	0 Å²	0	27.6 Å²	27.6	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-71.1	-36.6	179.9	-63.8	-12.8	0	0	0	111.8	T63 N67 L90 I92 F96 T97 G98 N326	T63-D94 VanDerWaalsContact CG2-O 3.29Å; T63-D94 WeakPolarHBondContact CG2-O 3.4Å; N67-D94 WeakPolarHBondContact ND2-CB 3.45Å; L90-D94 WeakPolarHBondContact O-CB 3.29Å; L90-D94 PolarHBondContact O-N 2.99Å; I92-D94 PolarHBondContact O-N 3.43Å; D94-F96 VanDerWaalsContact C-N 3.35Å; D94-T97 WeakPolarHBondContact O-CB 3.45Å; D94-T97 PolarHBondContact O-N 3.49Å; D94-G98 PolarHBondContact O-N 2.91Å; D94-N326 PolarHBondContact OD2-ND2 2.81Å
95	S	97.8	Very high	96.1	Very high	20 Å²	20	29 Å²	29	14%	0.14	15%	0.151	C	C	.	.	H	α-helix	trans	-59.8	-45.5	171.1	-76.5	0	0	0	0	111.5	I64 N67 A91 I92 T97 G98 L99	I64-S95 WeakPolarHBondContact CD1-O 3.41Å; N67-S95 VanDerWaalsContact CB-OG 3.23Å; N67-S95 WeakPolarHBondContact CB-OG 2.72Å; A91-S95 VanDerWaalsContact O-CB 3.29Å; A91-S95 WeakPolarHBondContact O-CB 3.35Å; A91-S95 PolarHBondContact O-N 2.95Å; A91-S95 PolarHBondContact O-OG 3.26Å; A91-S95 VanDerWaalsContact O-OG 3.08Å; I92-S95 PolarHBondContact O-N 3.14Å; S95-T97 VanDerWaalsContact C-N 3.34Å; S95-G98 PolarHBondContact O-N 3.5Å; S95-L99 PolarHBondContact O-N 3.03Å; S95-L99 VanDerWaalsContact O-N 3.09Å
96	F	97.7	Very high	96.1	Very high	103 Å²	103	26.3 Å²	26.3	45%	0.452	14%	0.139	S	C	.	.	H	α-helix	trans	-66.2	-37	174.1	-79.3	-66.3	0	0	0	111.9	I92 T93 D94 G98 L99 V100 L131	I92-F96 HydrophobicContact CG2-CD2 3.76Å; I92-F96 HydrophobicContact CG2-CE2 3.66Å; I92-F96 WeakPolarHBondContact O-CD2 3.43Å; I92-F96 PolarHBondContact O-N 3.13Å; T93-F96 PolarHBondContact O-N 3.42Å; D94-F96 VanDerWaalsContact C-N 3.35Å; F96-G98 VanDerWaalsContact C-N 3.31Å; F96-G98 PolarHBondContact O-N 3.48Å; F96-L99 PolarHBondContact O-N 3Å; F96-V100 WeakPolarHBondContact O-CB 3.4Å; F96-V100 WeakPolarHBondContact O-CG2 3.28Å; F96-V100 PolarHBondContact O-N 3.16Å; F96-L131 HydrophobicContact CB-CD1 3.82Å; F96-L131 HydrophobicContact CB-CD2 3.46Å; F96-L131 VanDerWaalsContact CB-CD2 3.46Å; F96-L131 HydrophobicContact CB-CG 4.3Å; F96-L131 HydrophobicContact CG-CD2 4.37Å
97	T	97.4	Very high	96	Very high	10 Å²	10	30.3 Å²	30.3	6%	0.061	16%	0.161	C	C	.	.	H	α-helix	trans	-61.6	-40.7	174.8	-59.5	0	0	0	0	110.9	T93 D94 S95 N101 I102 S323	T93-T97 WeakPolarHBondContact O-CB 3.5Å; T93-T97 PolarHBondContact O-N 3.37Å; T93-T97 PolarHBondContact O-OG1 3.39Å; D94-T97 WeakPolarHBondContact O-CB 3.45Å; D94-T97 PolarHBondContact O-N 3.49Å; S95-T97 VanDerWaalsContact C-N 3.34Å; T97-N101 HydrophobicContact CG2-CB 4.08Å; T97-N101 WeakPolarHBondContact O-CA 3.39Å; T97-N101 WeakPolarHBondContact O-CB 3.47Å; T97-N101 PolarHBondContact O-N 3.07Å; T97-I102 PolarHBondContact O-N 3.07Å; T97-I102 VanDerWaalsContact O-N 3.13Å; T97-S323 WeakPolarHBondContact CG2-OG 3.32Å
98	G	97.4	Very high	95.7	Very high	0 Å²	0	33.2 Å²	33.2	0%	0	17%	0.172	C	C	.	.	I	π-helix	trans	-59.6	-46.6	171.9	0	0	0	0	0	112.5	F60 D94 S95 F96 L103	F60-G98 WeakPolarHBondContact CD2-O 3.3Å; F60-G98 WeakPolarHBondContact CE2-O 3.5Å; D94-G98 PolarHBondContact O-N 2.91Å; S95-G98 PolarHBondContact O-N 3.5Å; F96-G98 VanDerWaalsContact C-N 3.31Å; F96-G98 PolarHBondContact O-N 3.48Å; G98-L103 PolarHBondContact O-N 3.49Å
99	L	97	Very high	95.3	Very high	90 Å²	90	33.4 Å²	33.4	47%	0.471	17%	0.168	S	C	.	.	I	π-helix	trans	-74.8	-37.6	-176.8	-177.2	64.4	0	0	0	113.8	I64 S95 F96 L103	I64-L99 HydrophobicContact CD1-CB 4.47Å; S95-L99 PolarHBondContact O-N 3.03Å; S95-L99 VanDerWaalsContact O-N 3.09Å; F96-L99 PolarHBondContact O-N 3Å; L99-L103 HydrophobicContact CD1-CD2 3.71Å; L99-L103 VanDerWaalsContact O-CB 3.29Å; L99-L103 WeakPolarHBondContact O-CB 3.43Å
100	V	96.8	Very high	94.8	Very high	22 Å²	22	39.6 Å²	39.6	13%	0.133	20%	0.195	C	C	.	.	I	π-helix	trans	-98.1	-37.2	-172.4	176.5	0	0	0	0	111.4	F96 T104 L127 Q128 L131	F96-V100 WeakPolarHBondContact O-CB 3.4Å; F96-V100 WeakPolarHBondContact O-CG2 3.28Å; F96-V100 PolarHBondContact O-N 3.16Å; V100-T104 WeakPolarHBondContact O-CB 3.45Å; V100-T104 WeakPolarHBondContact O-CG2 3.3Å; V100-T104 PolarHBondContact O-OG1 3.35Å; V100-L127 HydrophobicContact CG1-CB 3.74Å; V100-Q128 HydrophobicContact CG1-CG 4.01Å; V100-L131 HydrophobicContact CB-CD1 3.7Å; V100-L131 HydrophobicContact CG1-CD1 4.09Å; V100-L131 HydrophobicContact CG2-CD1 4.03Å
101	N	95.7	Very high	94.4	Very high	35 Å²	35	42.8 Å²	42.8	19%	0.187	22%	0.215	C	C	.	.	I	π-helix	trans	-93.1	-59.3	-176.4	-56.4	14.5	0	0	0	109.4	T97 T104 D105 Q128	T97-N101 HydrophobicContact CG2-CB 4.08Å; T97-N101 WeakPolarHBondContact O-CA 3.39Å; T97-N101 WeakPolarHBondContact O-CB 3.47Å; T97-N101 PolarHBondContact O-N 3.07Å; N101-T104 PolarHBondContact O-OG1 2.93Å; N101-D105 WeakPolarHBondContact O-CB 3.49Å; N101-D105 PolarHBondContact O-N 3.07Å; N101-D105 VanDerWaalsContact O-N 3.08Å; N101-Q128 HydrophobicContact CB-CG 4.39Å; N101-Q128 PolarHBondContact ND2-O 2.91Å; N101-Q128 WeakPolarHBondContact OD1-CA 3.25Å; N101-Q128 WeakPolarHBondContact OD1-CG 3.35Å
102	I	96.3	Very high	93.7	Very high	5 Å²	5	44.2 Å²	44.2	3%	0.026	23%	0.23	C	C	.	.	I	π-helix	trans	-69.3	-47.8	-172.4	-49.4	178.9	0	0	0	111	L56 F60 T63 T97 T104 D105 I106 A320	L56-I102 HydrophobicContact CD2-CG2 4.39Å; F60-I102 HydrophobicContact CB-CG2 3.76Å; F60-I102 HydrophobicContact CD2-CB 4.33Å; F60-I102 HydrophobicContact CD2-CG2 4.39Å; T63-I102 HydrophobicContact CG2-CD1 4.31Å; T97-I102 PolarHBondContact O-N 3.07Å; T97-I102 VanDerWaalsContact O-N 3.13Å; I102-T104 PolarHBondContact O-N 3.25Å; I102-D105 PolarHBondContact O-N 3.43Å; I102-I106 HydrophobicContact CG2-CD1 4.05Å; I102-I106 WeakPolarHBondContact O-CG1 3.32Å; I102-I106 PolarHBondContact O-N 2.94Å; I102-A320 HydrophobicContact CD1-CB 3.79Å; I102-A320 HydrophobicContact CG1-CB 4Å
103	L	95.7	Very high	93.1	Very high	42 Å²	42	44.9 Å²	44.9	22%	0.22	23%	0.234	C	C	.	.	H	α-helix	trans	-63.1	-41.8	-179.6	-178.6	62.4	0	0	0	112.2	F60 G98 L99 D105 I106 N107	F60-L103 HydrophobicContact CD2-CB 4.22Å; F60-L103 HydrophobicContact CE1-CD1 4.48Å; F60-L103 HydrophobicContact CE2-CB 3.76Å; F60-L103 HydrophobicContact CE2-CD1 4.29Å; F60-L103 HydrophobicContact CE2-CG 4.41Å; F60-L103 HydrophobicContact CZ-CB 4.35Å; F60-L103 HydrophobicContact CZ-CD1 4.09Å; F60-L103 HydrophobicContact CZ-CD2 4.46Å; G98-L103 PolarHBondContact O-N 3.49Å; L99-L103 HydrophobicContact CD1-CD2 3.71Å; L99-L103 VanDerWaalsContact O-CB 3.29Å; L99-L103 WeakPolarHBondContact O-CB 3.43Å; L103-D105 VanDerWaalsContact C-N 3.33Å; L103-I106 WeakPolarHBondContact O-CB 3.12Å; L103-I106 PolarHBondContact O-N 3.03Å; L103-N107 WeakPolarHBondContact CD1-ND2 3.48Å; L103-N107 PolarHBondContact O-N 3.47Å; L103-N107 PolarHBondContact O-ND2 3.17Å
104	T	93.5	Very high	92.7	Very high	39 Å²	39	46.1 Å²	46.1	24%	0.239	24%	0.239	C	C	.	.	H	α-helix	trans	-69.4	-34.1	-180	62.9	0	0	0	0	111.6	V100 N101 I102 N107 W108 V124 Q128	V100-T104 WeakPolarHBondContact O-CB 3.45Å; V100-T104 WeakPolarHBondContact O-CG2 3.3Å; V100-T104 PolarHBondContact O-OG1 3.35Å; N101-T104 PolarHBondContact O-OG1 2.93Å; I102-T104 PolarHBondContact O-N 3.25Å; T104-N107 PolarHBondContact O-N 2.91Å; T104-W108 VanDerWaalsContact O-CB 3.29Å; T104-W108 WeakPolarHBondContact O-CB 3.08Å; T104-W108 PolarHBondContact O-N 3.3Å; T104-V124 HydrophobicContact CG2-CG1 3.84Å; T104-Q128 PolarHBondContact OG1-NE2 3.46Å
105	D	92.4	Very high	92.2	Very high	49 Å²	49	51.5 Å²	51.5	26%	0.262	27%	0.272	S	S	.	.	H	α-helix	trans	-63.8	-41.7	171.7	-171.5	43.5	0	0	0	111.9	L56 N101 I102 L103 W108 R109	L56-D105 VanDerWaalsContact CD1-OD2 3.28Å; L56-D105 WeakPolarHBondContact CD1-OD2 3.34Å; N101-D105 WeakPolarHBondContact O-CB 3.49Å; N101-D105 PolarHBondContact O-N 3.07Å; N101-D105 VanDerWaalsContact O-N 3.08Å; I102-D105 PolarHBondContact O-N 3.43Å; L103-D105 VanDerWaalsContact C-N 3.33Å; D105-W108 WeakPolarHBondContact O-CB 3.45Å; D105-W108 PolarHBondContact O-N 3.03Å; D105-R109 WeakPolarHBondContact O-CB 3.49Å; D105-R109 WeakPolarHBondContact O-CD 3.43Å; D105-R109 WeakPolarHBondContact O-CG 3.34Å; D105-R109 PolarHBondContact O-N 2.99Å; D105-R109 IonicContact OD1-CZ 2.87Å; D105-R109 IonicContact OD1-NE 3.66Å; D105-R109 PolarHBondContact OD1-NE 2.97Å; D105-R109 VanDerWaalsContact OD1-NE 3.12Å; D105-R109 IonicContact OD1-NH2 2.73Å; D105-R109 IonicContact OD2-CZ 3.44Å; D105-R109 IonicContact OD2-NE 2.75Å; D105-R109 PolarHBondContact OD2-NE 3.27Å; D105-R109 IonicContact OD2-NH2 2.68Å; D105-R109 PolarHBondContact OD2-NH2 3.2Å
106	I	93.4	Very high	91.9	Very high	4 Å²	4	51.8 Å²	51.8	2%	0.021	28%	0.276	C	S	.	.	H	α-helix	trans	-59.8	-48.9	173.3	-71.3	168.1	0	0	0	111.2	L53 L56 W57 F60 I102 L103 W108 R109 F110	L53-I106 HydrophobicContact CD1-CG2 4.09Å; L56-I106 HydrophobicContact CB-CD1 4.21Å; L56-I106 HydrophobicContact CB-CG1 3.81Å; W57-I106 HydrophobicContact CD2-CD1 3.91Å; W57-I106 HydrophobicContact CD2-CG2 4.15Å; W57-I106 HydrophobicContact CE3-CD1 4.02Å; W57-I106 HydrophobicContact CG-CD1 4.24Å; W57-I106 HydrophobicContact CH2-CG2 4.08Å; W57-I106 HydrophobicContact CZ2-CG2 3.38Å; W57-I106 HydrophobicContact CZ3-CD1 4.45Å; F60-I106 HydrophobicContact CB-CD1 3.84Å; F60-I106 HydrophobicContact CG-CD1 4.23Å; I102-I106 HydrophobicContact CG2-CD1 4.05Å; I102-I106 WeakPolarHBondContact O-CG1 3.32Å; I102-I106 PolarHBondContact O-N 2.94Å; L103-I106 WeakPolarHBondContact O-CB 3.12Å; L103-I106 PolarHBondContact O-N 3.03Å; I106-W108 VanDerWaalsContact C-N 3.31Å; I106-W108 PolarHBondContact O-N 3.11Å; I106-R109 PolarHBondContact O-N 3.24Å; I106-F110 PolarHBondContact O-N 3Å
107	N	92.1	Very high	91.7	Very high	88 Å²	88	50.9 Å²	50.9	47%	0.471	28%	0.281	S	S	.	.	H	α-helix	trans	-61.4	-43.2	179.4	-80	-88	0	0	0	111	L103 T104 R109 F110 T111	L103-N107 WeakPolarHBondContact CD1-ND2 3.48Å; L103-N107 PolarHBondContact O-N 3.47Å; L103-N107 PolarHBondContact O-ND2 3.17Å; T104-N107 PolarHBondContact O-N 2.91Å; N107-R109 PolarHBondContact O-N 3.11Å; N107-F110 PolarHBondContact O-N 3.08Å; N107-T111 PolarHBondContact O-N 2.75Å; N107-T111 PolarHBondContact O-OG1 2.58Å
108	W	89.1	Confident	91.5	Very high	63 Å²	63	52.9 Å²	52.9	24%	0.239	29%	0.291	C	S	.	.	H	α-helix	trans	-55.8	-49.2	175.9	-173.4	-91.9	0	0	0	112.5	T104 D105 I106 F110 G112 F114 Q196 C197	T104-W108 VanDerWaalsContact O-CB 3.29Å; T104-W108 WeakPolarHBondContact O-CB 3.08Å; T104-W108 PolarHBondContact O-N 3.3Å; D105-W108 WeakPolarHBondContact O-CB 3.45Å; D105-W108 PolarHBondContact O-N 3.03Å; I106-W108 VanDerWaalsContact C-N 3.31Å; I106-W108 PolarHBondContact O-N 3.11Å; W108-F110 VanDerWaalsContact C-N 3.29Å; W108-F110 PolarHBondContact O-N 3.03Å; W108-G112 PolarHBondContact O-N 3.21Å; W108-F114 HydrophobicContact CE3-CB 4.46Å; W108-F114 HydrophobicContact CE3-CD2 4.05Å; W108-F114 HydrophobicContact CH2-CB 3.68Å; W108-F114 HydrophobicContact CH2-CD2 4.39Å; W108-F114 HydrophobicContact CH2-CG 4.27Å; W108-F114 HydrophobicContact CZ3-CB 3.45Å; W108-F114 VanDerWaalsContact CZ3-CB 3.45Å; W108-F114 AromaticContact CZ3-CD2 3.4Å; W108-F114 HydrophobicContact CZ3-CD2 3.4Å; W108-F114 HydrophobicContact CZ3-CE2 4.37Å; W108-F114 AromaticContact CZ3-CG 3.68Å; W108-F114 HydrophobicContact CZ3-CG 3.68Å; W108-Q196 HydrophobicContact CH2-CB 4.28Å; W108-Q196 HydrophobicContact CZ2-CB 4.3Å; W108-C197 HydrophobicContact CH2-CB 3.63Å; W108-C197 HydrophobicContact CZ3-CB 3.63Å
109	R	87.2	Confident	91.4	Very high	41 Å²	41	58.7 Å²	58.7	16%	0.155	32%	0.321	C	S	.	.	H	α-helix	trans	-66.5	-31.5	-179.3	-69.8	164	-179.3	-83	6.9	112.9	K49 Q52 L53 D105 I106 N107	K49-R109 WeakPolarHBondContact CE-O 3.17Å; K49-R109 PolarHBondContact NZ-O 3.41Å; Q52-R109 VanDerWaalsContact CD-CZ 3.44Å; L53-R109 HydrophobicContact CD1-CB 4.41Å; D105-R109 WeakPolarHBondContact O-CB 3.49Å; D105-R109 WeakPolarHBondContact O-CD 3.43Å; D105-R109 WeakPolarHBondContact O-CG 3.34Å; D105-R109 PolarHBondContact O-N 2.99Å; D105-R109 IonicContact OD1-CZ 2.87Å; D105-R109 IonicContact OD1-NE 3.66Å; D105-R109 PolarHBondContact OD1-NE 2.97Å; D105-R109 VanDerWaalsContact OD1-NE 3.12Å; D105-R109 IonicContact OD1-NH2 2.73Å; D105-R109 IonicContact OD2-CZ 3.44Å; D105-R109 IonicContact OD2-NE 2.75Å; D105-R109 PolarHBondContact OD2-NE 3.27Å; D105-R109 IonicContact OD2-NH2 2.68Å; D105-R109 PolarHBondContact OD2-NH2 3.2Å; I106-R109 PolarHBondContact O-N 3.24Å; N107-R109 PolarHBondContact O-N 3.11Å
110	F	86.8	Confident	91.3	Very high	163 Å²	163	57.4 Å²	57.4	72%	0.715	32%	0.317	S	S	*	.	H	α-helix	trans	-74.7	-48.8	177.6	-172.5	-94.9	0	0	0	112	I106 N107 W108	I106-F110 PolarHBondContact O-N 3Å; N107-F110 PolarHBondContact O-N 3.08Å; W108-F110 VanDerWaalsContact C-N 3.29Å; W108-F110 PolarHBondContact O-N 3.03Å
111	T	87.3	Confident	91.3	Very high	72 Å²	72	56.3 Å²	56.3	44%	0.442	31%	0.311	S	S	.	.	H	α-helix	trans	-74.7	-32	-177	-52.6	0	0	0	0	112.6	N107 D113 T115	N107-T111 PolarHBondContact O-N 2.75Å; N107-T111 PolarHBondContact O-OG1 2.58Å; T111-D113 WeakPolarHBondContact CG2-O 3.24Å; T111-D113 PolarHBondContact O-N 3.49Å; T111-T115 HydrophobicContact CG2-CG2 4.18Å
112	G	81.6	Confident	91.3	Very high	33 Å²	33	58.4 Å²	58.4	34%	0.34	32%	0.316	S	S	.	.	S	Bend	trans	76.5	-40	-174.1	0	0	0	0	0	113.2	W108 Q196	W108-G112 PolarHBondContact O-N 3.21Å; G112-Q196 PolarHBondContact O-NE2 3.05Å
113	D	85.9	Confident	91.3	Very high	64 Å²	64	61.1 Å²	61.1	34%	0.342	33%	0.332	S	S	.	.	S	Bend	trans	-110.6	150	176.4	-78.6	-47.3	0	0	0	113.8	T111 T115 E194 V195	T111-D113 WeakPolarHBondContact CG2-O 3.24Å; T111-D113 PolarHBondContact O-N 3.49Å; D113-T115 PolarHBondContact O-N 3.46Å; D113-E194 WeakPolarHBondContact OD1-CA 3.34Å; D113-E194 WeakPolarHBondContact OD1-CB 3.47Å; D113-V195 PolarHBondContact OD1-N 3.28Å; D113-V195 VanDerWaalsContact OD1-N 3.15Å
114	F	88.5	Confident	91.4	Very high	25 Å²	25	60.8 Å²	60.8	11%	0.11	33%	0.332	C	S	.	.			trans	-86.1	95.9	170.8	-169	-112	0	0	0	112.4	W108 A116 P117 V120 C121 K187 V195 C197	W108-F114 HydrophobicContact CE3-CB 4.46Å; W108-F114 HydrophobicContact CE3-CD2 4.05Å; W108-F114 HydrophobicContact CH2-CB 3.68Å; W108-F114 HydrophobicContact CH2-CD2 4.39Å; W108-F114 HydrophobicContact CH2-CG 4.27Å; W108-F114 HydrophobicContact CZ3-CB 3.45Å; W108-F114 VanDerWaalsContact CZ3-CB 3.45Å; W108-F114 AromaticContact CZ3-CD2 3.4Å; W108-F114 HydrophobicContact CZ3-CD2 3.4Å; W108-F114 HydrophobicContact CZ3-CE2 4.37Å; W108-F114 AromaticContact CZ3-CG 3.68Å; W108-F114 HydrophobicContact CZ3-CG 3.68Å; F114-A116 HydrophobicContact CD2-CB 4.37Å; F114-A116 HydrophobicContact CE1-CB 3.95Å; F114-A116 WeakPolarHBondContact CE1-O 3.49Å; F114-A116 HydrophobicContact CE2-CB 3.65Å; F114-A116 HydrophobicContact CZ-CB 3.4Å; F114-P117 WeakPolarHBondContact CE1-O 3.26Å; F114-V120 HydrophobicContact CZ-CB 4.44Å; F114-C121 HydrophobicContact CD1-CB 4.4Å; F114-C121 HydrophobicContact CE1-CB 3.52Å; F114-C121 HydrophobicContact CE2-CB 4.45Å; F114-C121 HydrophobicContact CZ-CB 3.53Å; F114-K187 HydrophobicContact CD1-CD 4.11Å; F114-K187 HydrophobicContact CD1-CG 4.14Å; F114-K187 HydrophobicContact CE1-CD 4.32Å; F114-V195 VanDerWaalsContact CB-O 3.32Å; F114-V195 WeakPolarHBondContact CB-O 3.48Å; F114-V195 PolarHBondContact N-O 3.17Å; F114-V195 WeakPolarHBondContact O-CG1 3.47Å; F114-C197 HydrophobicContact CB-CB 4.5Å; F114-C197 HydrophobicContact CD1-CB 4.16Å; F114-C197 HydrophobicContact CD2-CB 4.25Å; F114-C197 HydrophobicContact CE1-CB 4.47Å; F114-C197 HydrophobicContact CE2-CB 4.5Å; F114-C197 HydrophobicContact CG-CB 4.03Å
115	T	87.4	Confident	91.5	Very high	113 Å²	113	61.7 Å²	61.7	69%	0.693	33%	0.331	S	S	*	.			trans	-80.7	-21.9	179.3	56.5	0	0	0	0	113.4	T111 D113	T111-T115 HydrophobicContact CG2-CG2 4.18Å; D113-T115 PolarHBondContact O-N 3.46Å
116	A	90.4	Very high	91.8	Very high	26 Å²	26	61.1 Å²	61.1	22%	0.215	33%	0.326	C	S	.	.	S	Bend	trans	-70.5	164.9	-173.9	0	0	0	0	0	113.4	F114 V120 K187	F114-A116 HydrophobicContact CD2-CB 4.37Å; F114-A116 HydrophobicContact CE1-CB 3.95Å; F114-A116 WeakPolarHBondContact CE1-O 3.49Å; F114-A116 HydrophobicContact CE2-CB 3.65Å; F114-A116 HydrophobicContact CZ-CB 3.4Å; A116-V120 HydrophobicContact CB-CB 4.08Å; A116-V120 HydrophobicContact CB-CG1 4.05Å; A116-K187 PolarHBondContact O-NZ 3.32Å
117	P	93.4	Very high	92	Very high	85 Å²	85	63.9 Å²	63.9	55%	0.552	34%	0.34	S	S	*	.			trans	-63.2	155.8	174.7	-22.6	33.7	0	0	0	113.3	F114 L119 V120 C121	F114-P117 WeakPolarHBondContact CE1-O 3.26Å; P117-L119 VanDerWaalsContact C-N 3.27Å; P117-L119 PolarHBondContact O-N 3.33Å; P117-V120 HydrophobicContact CB-CG2 4.41Å; P117-V120 HydrophobicContact CG-CG2 4.33Å; P117-V120 WeakPolarHBondContact O-CB 3.47Å; P117-V120 PolarHBondContact O-N 3.44Å; P117-C121 PolarHBondContact O-N 3.3Å
118	D	94.2	Very high	92.3	Very high	51 Å²	51	61.3 Å²	61.3	27%	0.273	33%	0.325	S	S	.	.	H	α-helix	trans	-55.1	-40.2	177	-179.6	56.6	0	0	0	113	V120 C121 R122 G186 K187	D118-V120 VanDerWaalsContact C-N 3.27Å; D118-V120 PolarHBondContact O-N 2.91Å; D118-C121 WeakPolarHBondContact O-CB 3.03Å; D118-C121 PolarHBondContact O-N 3.47Å; D118-C121 VanDerWaalsContact O-N 3.12Å; D118-R122 WeakPolarHBondContact O-CG 3.23Å; D118-R122 PolarHBondContact O-N 3.34Å; D118-R122 IonicContact OD1-NE 3.78Å; D118-R122 IonicContact OD1-NH2 3.81Å; D118-R122 IonicContact OD2-CZ 3.03Å; D118-R122 VanDerWaalsContact OD2-CZ 3.24Å; D118-R122 IonicContact OD2-NE 3.82Å; D118-R122 PolarHBondContact OD2-NE 2.93Å; D118-R122 IonicContact OD2-NH2 2.61Å; D118-R122 PolarHBondContact OD2-NH2 3.14Å; D118-G186 WeakPolarHBondContact OD1-CA 3.12Å; D118-K187 HydrophobicContact CB-CB 3.94Å; D118-K187 WeakPolarHBondContact OD1-CB 3.44Å; D118-K187 PolarHBondContact OD1-N 2.98Å
119	L	95.4	Very high	92.7	Very high	122 Å²	122	59.4 Å²	59.4	64%	0.639	32%	0.321	S	S	*	.	H	α-helix	trans	-57.9	-39.6	176.2	-178.5	63.6	0	0	0	112.4	P117 R122 V123	P117-L119 VanDerWaalsContact C-N 3.27Å; P117-L119 PolarHBondContact O-N 3.33Å; L119-R122 PolarHBondContact O-N 2.88Å; L119-V123 HydrophobicContact CD1-CG2 4.16Å; L119-V123 HydrophobicContact CG-CG2 4.42Å; L119-V123 WeakPolarHBondContact O-CB 3.27Å; L119-V123 VanDerWaalsContact O-CG2 3.28Å; L119-V123 WeakPolarHBondContact O-CG2 3.25Å; L119-V123 PolarHBondContact O-N 3.37Å
120	V	95	Very high	93.2	Very high	63 Å²	63	57.6 Å²	57.6	38%	0.382	31%	0.314	S	S	.	.	H	α-helix	trans	-66.8	-40.8	178.6	177.7	0	0	0	0	110.2	F114 A116 P117 D118 V123 V124	F114-V120 HydrophobicContact CZ-CB 4.44Å; A116-V120 HydrophobicContact CB-CB 4.08Å; A116-V120 HydrophobicContact CB-CG1 4.05Å; P117-V120 HydrophobicContact CB-CG2 4.41Å; P117-V120 HydrophobicContact CG-CG2 4.33Å; P117-V120 WeakPolarHBondContact O-CB 3.47Å; P117-V120 PolarHBondContact O-N 3.44Å; D118-V120 VanDerWaalsContact C-N 3.27Å; D118-V120 PolarHBondContact O-N 2.91Å; V120-V123 PolarHBondContact O-N 3Å; V120-V124 HydrophobicContact CG1-CG2 4.02Å; V120-V124 VanDerWaalsContact O-CB 3.29Å; V120-V124 WeakPolarHBondContact O-CB 3.38Å; V120-V124 WeakPolarHBondContact O-CG2 3.41Å; V120-V124 PolarHBondContact O-N 3.39Å
121	C	95.1	Very high	93.7	Very high	0 Å²	0	50.2 Å²	50.2	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-56.7	-52.5	174.8	167.1	0	0	0	0	111.1	F114 P117 D118 V123 V124 R125 G186 C197	F114-C121 HydrophobicContact CD1-CB 4.4Å; F114-C121 HydrophobicContact CE1-CB 3.52Å; F114-C121 HydrophobicContact CE2-CB 4.45Å; F114-C121 HydrophobicContact CZ-CB 3.53Å; P117-C121 PolarHBondContact O-N 3.3Å; D118-C121 WeakPolarHBondContact O-CB 3.03Å; D118-C121 PolarHBondContact O-N 3.47Å; D118-C121 VanDerWaalsContact O-N 3.12Å; C121-V123 PolarHBondContact O-N 3.33Å; C121-V124 PolarHBondContact O-N 3.04Å; C121-R125 WeakPolarHBondContact O-CB 3.42Å; C121-R125 VanDerWaalsContact O-CG 3.31Å; C121-R125 WeakPolarHBondContact O-CG 3.48Å; C121-R125 PolarHBondContact O-N 2.99Å; C121-G186 VanDerWaalsContact SG-CA 3.51Å; C121-C197 VanDerWaalsContact CA-SG 3.53Å; C121-C197 HydrophobicContact CB-CB 3.83Å; C121-C197 WeakPolarHBondContact CB-SG 3.23Å; C121-C197 VanDerWaalsContact SG-CA 3.51Å; C121-C197 WeakPolarHBondContact SG-CB 3.14Å; C121-C197 CovalentContact SG-SG 2.02Å; C121-C197 PolarHBondContact SG-SG 3.18Å
122	R	96.9	Very high	94.2	Very high	79 Å²	79	48.1 Å²	48.1	30%	0.298	27%	0.268	S	S	.	.	H	α-helix	trans	-58.1	-49.1	-179.9	-67	178.5	-167.6	-114.4	4.4	112.2	D118 L119 Y126 L182 F185	D118-R122 WeakPolarHBondContact O-CG 3.23Å; D118-R122 PolarHBondContact O-N 3.34Å; D118-R122 IonicContact OD1-NE 3.78Å; D118-R122 IonicContact OD1-NH2 3.81Å; D118-R122 IonicContact OD2-CZ 3.03Å; D118-R122 VanDerWaalsContact OD2-CZ 3.24Å; D118-R122 IonicContact OD2-NE 3.82Å; D118-R122 PolarHBondContact OD2-NE 2.93Å; D118-R122 IonicContact OD2-NH2 2.61Å; D118-R122 PolarHBondContact OD2-NH2 3.14Å; L119-R122 PolarHBondContact O-N 2.88Å; R122-Y126 WeakPolarHBondContact O-CB 3.24Å; R122-Y126 PolarHBondContact O-N 3.44Å; R122-L182 HydrophobicContact CB-CD2 4.31Å; R122-L182 PolarHBondContact NH1-O 3.41Å; R122-F185 VanDerWaalsContact CG-O 3.32Å; R122-F185 WeakPolarHBondContact CG-O 3.46Å
123	V	96.8	Very high	95	Very high	61 Å²	61	46.8 Å²	46.8	37%	0.37	25%	0.252	S	S	.	.	H	α-helix	trans	-66.4	-43.4	-177.8	171.9	0	0	0	0	111.3	L119 V120 C121 Y126 L127	L119-V123 HydrophobicContact CD1-CG2 4.16Å; L119-V123 HydrophobicContact CG-CG2 4.42Å; L119-V123 WeakPolarHBondContact O-CB 3.27Å; L119-V123 VanDerWaalsContact O-CG2 3.28Å; L119-V123 WeakPolarHBondContact O-CG2 3.25Å; L119-V123 PolarHBondContact O-N 3.37Å; V120-V123 PolarHBondContact O-N 3Å; C121-V123 PolarHBondContact O-N 3.33Å; V123-Y126 PolarHBondContact O-N 2.87Å; V123-L127 HydrophobicContact CG1-CD1 3.95Å; V123-L127 HydrophobicContact CG1-CG 4.4Å; V123-L127 WeakPolarHBondContact O-CB 3.48Å; V123-L127 WeakPolarHBondContact O-CG 3.13Å; V123-L127 PolarHBondContact O-N 3.44Å
124	V	96.8	Very high	95.6	Very high	36 Å²	36	43.7 Å²	43.7	22%	0.218	24%	0.236	C	C	.	.	H	α-helix	trans	-63.3	-50.4	177.9	169.3	0	0	0	0	110.4	T104 V120 C121 Y126 L127 Q128	T104-V124 HydrophobicContact CG2-CG1 3.84Å; V120-V124 HydrophobicContact CG1-CG2 4.02Å; V120-V124 VanDerWaalsContact O-CB 3.29Å; V120-V124 WeakPolarHBondContact O-CB 3.38Å; V120-V124 WeakPolarHBondContact O-CG2 3.41Å; V120-V124 PolarHBondContact O-N 3.39Å; C121-V124 PolarHBondContact O-N 3.04Å; V124-Y126 VanDerWaalsContact C-N 3.32Å; V124-Y126 PolarHBondContact O-N 3.36Å; V124-L127 PolarHBondContact O-N 3.36Å; V124-Q128 HydrophobicContact CG1-CG 4.32Å; V124-Q128 VanDerWaalsContact O-CG 3.27Å; V124-Q128 WeakPolarHBondContact O-CG 3.33Å; V124-Q128 PolarHBondContact O-N 2.89Å
125	R	96.8	Very high	95.9	Very high	57 Å²	57	42.8 Å²	42.8	22%	0.215	23%	0.233	C	C	.	.	H	α-helix	trans	-59.7	-42.5	178.1	-70.3	-62.6	-169.7	-175.8	4.5	112	C121 Q128 V129 T181 F185 C197	C121-R125 WeakPolarHBondContact O-CB 3.42Å; C121-R125 VanDerWaalsContact O-CG 3.31Å; C121-R125 WeakPolarHBondContact O-CG 3.48Å; C121-R125 PolarHBondContact O-N 2.99Å; R125-Q128 PolarHBondContact O-N 3.5Å; R125-V129 WeakPolarHBondContact O-CG2 3.46Å; R125-V129 PolarHBondContact O-N 3.14Å; R125-V129 VanDerWaalsContact O-N 3.16Å; R125-T181 HydrophobicContact CB-CG2 3.97Å; R125-F185 HydrophobicContact CB-CB 4.07Å; R125-F185 HydrophobicContact CB-CG 4.25Å; R125-F185 HydrophobicContact CG-CB 4.06Å; R125-F185 HydrophobicContact CG-CD1 4.08Å; R125-F185 HydrophobicContact CG-CG 4.2Å; R125-C197 PolarHBondContact NE-O 3.22Å; R125-C197 PolarHBondContact NH2-O 3.06Å
126	Y	97.9	Very high	96.4	Very high	38 Å²	38	37.4 Å²	37.4	15%	0.149	20%	0.2	C	C	.	.	H	α-helix	trans	-59.4	-52	174.8	174.2	-111.3	0	0	0	112.2	R122 V123 V124 Q128 V129 V130 F175 S178 L182	R122-Y126 WeakPolarHBondContact O-CB 3.24Å; R122-Y126 PolarHBondContact O-N 3.44Å; V123-Y126 PolarHBondContact O-N 2.87Å; V124-Y126 VanDerWaalsContact C-N 3.32Å; V124-Y126 PolarHBondContact O-N 3.36Å; Y126-Q128 VanDerWaalsContact C-N 3.28Å; Y126-Q128 PolarHBondContact O-N 3.43Å; Y126-V129 PolarHBondContact O-N 2.8Å; Y126-V129 VanDerWaalsContact O-N 3.16Å; Y126-V130 HydrophobicContact CD1-CG2 4.18Å; Y126-V130 HydrophobicContact CD2-CG2 4.19Å; Y126-V130 HydrophobicContact CE1-CG2 3.84Å; Y126-V130 HydrophobicContact CE2-CG2 3.86Å; Y126-V130 HydrophobicContact CG-CG2 4.36Å; Y126-V130 WeakPolarHBondContact O-CG2 3.26Å; Y126-V130 PolarHBondContact O-N 3.09Å; Y126-F175 HydrophobicContact CE1-CD1 4.39Å; Y126-F175 PolarHBondContact OH-O 3.18Å; Y126-S178 VanDerWaalsContact CD2-O 3.22Å; Y126-S178 WeakPolarHBondContact CD2-O 3.27Å; Y126-S178 VanDerWaalsContact CE2-C 3.49Å; Y126-S178 VanDerWaalsContact CE2-CB 3.5Å; Y126-S178 WeakPolarHBondContact CE2-O 3.45Å; Y126-L182 VanDerWaalsContact CB-CD2 3.43Å; Y126-L182 HydrophobicContact CD1-CD1 4.2Å; Y126-L182 HydrophobicContact CD1-CD2 4.17Å; Y126-L182 HydrophobicContact CD1-CG 4.27Å; Y126-L182 HydrophobicContact CD2-CD1 3.7Å; Y126-L182 HydrophobicContact CD2-CD2 4.18Å; Y126-L182 HydrophobicContact CD2-CG 3.5Å; Y126-L182 HydrophobicContact CE1-CD1 4.31Å; Y126-L182 HydrophobicContact CE2-CD1 3.82Å; Y126-L182 HydrophobicContact CE2-CG 4.15Å; Y126-L182 HydrophobicContact CG-CD1 3.88Å; Y126-L182 HydrophobicContact CG-CD2 3.68Å; Y126-L182 HydrophobicContact CG-CG 3.55Å
127	L	97.9	Very high	96.7	Very high	62 Å²	62	37.4 Å²	37.4	33%	0.325	19%	0.194	S	C	.	.	H	α-helix	trans	-62.7	-35.9	179.5	-71.1	174.1	0	0	0	112.1	V100 V123 V124 V129 V130 L131	V100-L127 HydrophobicContact CG1-CB 3.74Å; V123-L127 HydrophobicContact CG1-CD1 3.95Å; V123-L127 HydrophobicContact CG1-CG 4.4Å; V123-L127 WeakPolarHBondContact O-CB 3.48Å; V123-L127 WeakPolarHBondContact O-CG 3.13Å; V123-L127 PolarHBondContact O-N 3.44Å; V124-L127 PolarHBondContact O-N 3.36Å; L127-V129 VanDerWaalsContact C-N 3.3Å; L127-V129 PolarHBondContact O-N 3.03Å; L127-V130 PolarHBondContact O-N 3.14Å; L127-L131 WeakPolarHBondContact O-CB 3.39Å; L127-L131 WeakPolarHBondContact O-CD1 3.44Å; L127-L131 VanDerWaalsContact O-CG 3.24Å; L127-L131 WeakPolarHBondContact O-CG 3.47Å; L127-L131 PolarHBondContact O-N 3.22Å
128	Q	97.7	Very high	96.9	Very high	33 Å²	33	33.4 Å²	33.4	15%	0.154	17%	0.168	C	C	.	.	H	α-helix	trans	-57.3	-46	174.6	-73.9	176.2	-13.1	0	0	111.7	V100 N101 T104 V124 R125 Y126 L132	V100-Q128 HydrophobicContact CG1-CG 4.01Å; N101-Q128 HydrophobicContact CB-CG 4.39Å; N101-Q128 PolarHBondContact ND2-O 2.91Å; N101-Q128 WeakPolarHBondContact OD1-CA 3.25Å; N101-Q128 WeakPolarHBondContact OD1-CG 3.35Å; T104-Q128 PolarHBondContact OG1-NE2 3.46Å; V124-Q128 HydrophobicContact CG1-CG 4.32Å; V124-Q128 VanDerWaalsContact O-CG 3.27Å; V124-Q128 WeakPolarHBondContact O-CG 3.33Å; V124-Q128 PolarHBondContact O-N 2.89Å; R125-Q128 PolarHBondContact O-N 3.5Å; Y126-Q128 VanDerWaalsContact C-N 3.28Å; Y126-Q128 PolarHBondContact O-N 3.43Å; Q128-L132 WeakPolarHBondContact O-CB 3.37Å; Q128-L132 PolarHBondContact O-N 3.19Å; Q128-L132 VanDerWaalsContact O-N 3.12Å
129	V	97.3	Very high	97	Very high	24 Å²	24	31.2 Å²	31.2	15%	0.145	16%	0.157	C	C	.	.	H	α-helix	trans	-72.3	-37.8	179.2	179.3	0	0	0	0	111.3	R125 Y126 L127 L131 L132 Y133 T181	R125-V129 WeakPolarHBondContact O-CG2 3.46Å; R125-V129 PolarHBondContact O-N 3.14Å; R125-V129 VanDerWaalsContact O-N 3.16Å; Y126-V129 PolarHBondContact O-N 2.8Å; Y126-V129 VanDerWaalsContact O-N 3.16Å; L127-V129 VanDerWaalsContact C-N 3.3Å; L127-V129 PolarHBondContact O-N 3.03Å; V129-L131 VanDerWaalsContact C-N 3.33Å; V129-L131 PolarHBondContact O-N 2.96Å; V129-L132 WeakPolarHBondContact O-CB 3.31Å; V129-L132 PolarHBondContact O-N 3.28Å; V129-Y133 HydrophobicContact CG1-CD2 3.63Å; V129-Y133 HydrophobicContact CG1-CE2 3.38Å; V129-Y133 WeakPolarHBondContact O-CD2 3.42Å; V129-Y133 PolarHBondContact O-N 3.38Å; V129-T181 HydrophobicContact CB-CG2 4.44Å; V129-T181 HydrophobicContact CG2-CG2 3.86Å
130	V	98.4	Very high	97.1	Very high	2 Å²	2	26.2 Å²	26.2	1%	0.012	13%	0.131	C	C	.	.	H	α-helix	trans	-57.5	-47.3	173.8	169.6	0	0	0	0	111.1	Y126 L127 L132 Y133 A134 F175 S178	Y126-V130 HydrophobicContact CD1-CG2 4.18Å; Y126-V130 HydrophobicContact CD2-CG2 4.19Å; Y126-V130 HydrophobicContact CE1-CG2 3.84Å; Y126-V130 HydrophobicContact CE2-CG2 3.86Å; Y126-V130 HydrophobicContact CG-CG2 4.36Å; Y126-V130 WeakPolarHBondContact O-CG2 3.26Å; Y126-V130 PolarHBondContact O-N 3.09Å; L127-V130 PolarHBondContact O-N 3.14Å; V130-L132 VanDerWaalsContact C-N 3.34Å; V130-Y133 PolarHBondContact O-N 3.09Å; V130-A134 VanDerWaalsContact O-CB 3.23Å; V130-A134 WeakPolarHBondContact O-CB 3.39Å; V130-A134 PolarHBondContact O-N 3.11Å; V130-F175 HydrophobicContact CB-CD1 4.44Å; V130-F175 HydrophobicContact CG1-CD1 3.7Å; V130-F175 HydrophobicContact CG1-CE1 3.58Å; V130-F175 HydrophobicContact CG1-CG 4.36Å; V130-F175 HydrophobicContact CG1-CZ 4.11Å; V130-F175 HydrophobicContact CG2-CD1 3.78Å; V130-F175 HydrophobicContact CG2-CE1 4.21Å; V130-S178 VanDerWaalsContact CA-OG 3.25Å; V130-S178 WeakPolarHBondContact CA-OG 3.35Å; V130-S178 VanDerWaalsContact CG2-CB 3.45Å; V130-S178 WeakPolarHBondContact CG2-OG 3.1Å; V130-S178 PolarHBondContact N-OG 3.16Å
131	L	98.1	Very high	97.2	Very high	9 Å²	9	23.5 Å²	23.5	5%	0.047	12%	0.115	C	C	.	.	H	α-helix	trans	-68.4	-34.9	-178	-68.5	166.8	0	0	0	112.2	T93 F96 V100 L127 V129 A134 S135 W171	T93-L131 HydrophobicContact CG2-CD2 4.12Å; F96-L131 HydrophobicContact CB-CD1 3.82Å; F96-L131 HydrophobicContact CB-CD2 3.46Å; F96-L131 VanDerWaalsContact CB-CD2 3.46Å; F96-L131 HydrophobicContact CB-CG 4.3Å; F96-L131 HydrophobicContact CG-CD2 4.37Å; V100-L131 HydrophobicContact CB-CD1 3.7Å; V100-L131 HydrophobicContact CG1-CD1 4.09Å; V100-L131 HydrophobicContact CG2-CD1 4.03Å; L127-L131 WeakPolarHBondContact O-CB 3.39Å; L127-L131 WeakPolarHBondContact O-CD1 3.44Å; L127-L131 VanDerWaalsContact O-CG 3.24Å; L127-L131 WeakPolarHBondContact O-CG 3.47Å; L127-L131 PolarHBondContact O-N 3.22Å; V129-L131 VanDerWaalsContact C-N 3.33Å; V129-L131 PolarHBondContact O-N 2.96Å; L131-A134 PolarHBondContact O-N 2.69Å; L131-S135 PolarHBondContact O-N 2.83Å; L131-S135 PolarHBondContact O-OG 2.99Å; L131-W171 HydrophobicContact CD2-CH2 4.47Å
132	L	96.8	Very high	97.2	Very high	28 Å²	28	23.8 Å²	23.8	15%	0.147	12%	0.117	C	C	.	.	H	α-helix	trans	-58.5	-51.2	171.1	172.2	59.4	0	0	0	112	Q128 V129 V130 S135 T136 V218 W287	Q128-L132 WeakPolarHBondContact O-CB 3.37Å; Q128-L132 PolarHBondContact O-N 3.19Å; Q128-L132 VanDerWaalsContact O-N 3.12Å; V129-L132 WeakPolarHBondContact O-CB 3.31Å; V129-L132 PolarHBondContact O-N 3.28Å; V130-L132 VanDerWaalsContact C-N 3.34Å; L132-S135 PolarHBondContact O-OG 3.35Å; L132-T136 PolarHBondContact O-N 2.78Å; L132-T136 PolarHBondContact O-OG1 2.91Å; L132-T136 VanDerWaalsContact O-OG1 3.06Å; L132-V218 HydrophobicContact CD1-CG1 3.56Å; L132-V218 HydrophobicContact CD2-CG1 4.18Å; L132-V218 HydrophobicContact CD2-CG2 4.06Å; L132-V218 HydrophobicContact CG-CG1 3.71Å; L132-V218 HydrophobicContact CG-CG2 4.05Å; L132-W287 HydrophobicContact CD1-CH2 3Å; L132-W287 HydrophobicContact CD1-CZ2 3.42Å; L132-W287 VanDerWaalsContact CD1-CZ2 3.42Å; L132-W287 HydrophobicContact CD1-CZ3 3.76Å; L132-W287 HydrophobicContact CG-CH2 4.42Å
133	Y	98	Very high	97.1	Very high	4 Å²	4	20 Å²	20	2%	0.016	10%	0.102	C	C	.	.	H	α-helix	trans	-65.7	-42.4	176.4	-78.8	-70.6	0	0	0	111.7	V129 V130 T136 Y137 S174 F177 S178 L217 V218	V129-Y133 HydrophobicContact CG1-CD2 3.63Å; V129-Y133 HydrophobicContact CG1-CE2 3.38Å; V129-Y133 WeakPolarHBondContact O-CD2 3.42Å; V129-Y133 PolarHBondContact O-N 3.38Å; V130-Y133 PolarHBondContact O-N 3.09Å; Y133-T136 PolarHBondContact O-N 3.25Å; Y133-Y137 HydrophobicContact CD1-CE1 4.41Å; Y133-Y137 AromaticContact CD1-CE2 3.84Å; Y133-Y137 HydrophobicContact CD1-CE2 3.84Å; Y133-Y137 AromaticContact CD1-CZ 3.65Å; Y133-Y137 WeakPolarHBondContact CD1-OH 3.44Å; Y133-Y137 HydrophobicContact CG-CE2 4.4Å; Y133-Y137 WeakPolarHBondContact O-CB 3.44Å; Y133-Y137 VanDerWaalsContact O-CG 3.31Å; Y133-Y137 PolarHBondContact O-N 3.46Å; Y133-S174 WeakPolarHBondContact CB-OG 3.31Å; Y133-S174 PolarHBondContact O-OG 3.47Å; Y133-F177 HydrophobicContact CE1-CB 4.37Å; Y133-F177 HydrophobicContact CE2-CB 4.28Å; Y133-S178 WeakPolarHBondContact CD2-OG 3.39Å; Y133-L217 HydrophobicContact CE1-CB 3.67Å; Y133-V218 HydrophobicContact CD1-CG2 3.63Å; Y133-V218 HydrophobicContact CE1-CB 4.41Å; Y133-V218 HydrophobicContact CE1-CG2 3.22Å; Y133-V218 HydrophobicContact CE2-CG2 4.21Å; Y133-V218 HydrophobicContact CG-CG2 4.26Å
134	A	98	Very high	97	Very high	0 Å²	0	19.1 Å²	19.1	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-61.5	-47.4	-177.1	0	0	0	0	0	112.1	T93 V130 L131 T136 Y137 V138 W171 S174	T93-A134 HydrophobicContact CG2-CB 3.82Å; V130-A134 VanDerWaalsContact O-CB 3.23Å; V130-A134 WeakPolarHBondContact O-CB 3.39Å; V130-A134 PolarHBondContact O-N 3.11Å; L131-A134 PolarHBondContact O-N 2.69Å; A134-T136 VanDerWaalsContact C-N 3.3Å; A134-T136 PolarHBondContact O-N 3.48Å; A134-Y137 PolarHBondContact O-N 3.2Å; A134-V138 WeakPolarHBondContact O-CB 3.27Å; A134-V138 WeakPolarHBondContact O-CG2 3.39Å; A134-V138 PolarHBondContact O-N 2.58Å; A134-W171 HydrophobicContact CB-CD2 4.44Å; A134-W171 HydrophobicContact CB-CE3 4.27Å; A134-W171 HydrophobicContact CB-CH2 4.37Å; A134-W171 HydrophobicContact CB-CZ3 4.24Å; A134-S174 WeakPolarHBondContact CA-OG 3.36Å; A134-S174 PolarHBondContact N-OG 3.36Å
135	S	95.9	Very high	96.8	Very high	5 Å²	5	17.4 Å²	17.4	4%	0.035	9%	0.085	C	C	.	.	H	α-helix	trans	-58.9	-46.4	179.8	61.5	0	0	0	0	110.6	L131 L132 V138 L139	L131-S135 PolarHBondContact O-N 2.83Å; L131-S135 PolarHBondContact O-OG 2.99Å; L132-S135 PolarHBondContact O-OG 3.35Å; S135-V138 PolarHBondContact O-N 3.47Å; S135-L139 WeakPolarHBondContact O-CG 3.36Å; S135-L139 PolarHBondContact O-N 2.94Å
136	T	97	Very high	96.5	Very high	0 Å²	0	15.2 Å²	15.2	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-61.2	-49.6	176.9	-59.5	0	0	0	0	112.6	L132 Y133 A134 V138 L139 V140 V218 P222 F283	L132-T136 PolarHBondContact O-N 2.78Å; L132-T136 PolarHBondContact O-OG1 2.91Å; L132-T136 VanDerWaalsContact O-OG1 3.06Å; Y133-T136 PolarHBondContact O-N 3.25Å; A134-T136 VanDerWaalsContact C-N 3.3Å; A134-T136 PolarHBondContact O-N 3.48Å; T136-V138 VanDerWaalsContact C-N 3.33Å; T136-V138 PolarHBondContact O-N 3.33Å; T136-L139 WeakPolarHBondContact O-CB 3.42Å; T136-L139 PolarHBondContact O-N 2.92Å; T136-L139 VanDerWaalsContact O-N 3.07Å; T136-V140 PolarHBondContact O-N 3.4Å; T136-V218 WeakPolarHBondContact CG2-O 3.43Å; T136-P222 HydrophobicContact CG2-CB 3.49Å; T136-P222 VanDerWaalsContact CG2-CB 3.49Å; T136-P222 HydrophobicContact CG2-CG 3.5Å; T136-P222 VanDerWaalsContact CG2-CG 3.5Å; T136-F283 HydrophobicContact CG2-CE2 4.28Å; T136-F283 HydrophobicContact CG2-CZ 4.26Å
137	Y	98.1	Very high	96.3	Very high	26 Å²	26	15.5 Å²	15.5	10%	0.102	8%	0.078	C	C	.	.	H	α-helix	trans	-73.6	-24.6	-176.7	-65	-16.1	0	0	0	113	Y133 A134 L139 V140 S141 L173 F177 L217 P222	Y133-Y137 HydrophobicContact CD1-CE1 4.41Å; Y133-Y137 AromaticContact CD1-CE2 3.84Å; Y133-Y137 HydrophobicContact CD1-CE2 3.84Å; Y133-Y137 AromaticContact CD1-CZ 3.65Å; Y133-Y137 WeakPolarHBondContact CD1-OH 3.44Å; Y133-Y137 HydrophobicContact CG-CE2 4.4Å; Y133-Y137 WeakPolarHBondContact O-CB 3.44Å; Y133-Y137 VanDerWaalsContact O-CG 3.31Å; Y133-Y137 PolarHBondContact O-N 3.46Å; A134-Y137 PolarHBondContact O-N 3.2Å; Y137-L139 VanDerWaalsContact C-N 3.33Å; Y137-V140 PolarHBondContact O-N 3.01Å; Y137-S141 VanDerWaalsContact O-CB 3.32Å; Y137-S141 WeakPolarHBondContact O-CB 3.26Å; Y137-S141 PolarHBondContact O-N 2.85Å; Y137-S141 PolarHBondContact O-OG 3.27Å; Y137-L173 HydrophobicContact CD2-CB 3.98Å; Y137-L173 HydrophobicContact CE2-CB 3.88Å; Y137-F177 AromaticContact CE2-CD2 3.93Å; Y137-F177 HydrophobicContact CE2-CD2 3.93Å; Y137-F177 HydrophobicContact CE2-CE2 4.24Å; Y137-F177 WeakPolarHBondContact OH-CD2 3.35Å; Y137-L217 WeakPolarHBondContact CE1-O 3.48Å; Y137-L217 PolarHBondContact OH-O 2.99Å; Y137-L217 VanDerWaalsContact OH-O 3.08Å; Y137-P222 HydrophobicContact CD1-CG 4.5Å; Y137-P222 HydrophobicContact CE1-CG 4.03Å
138	V	97.2	Very high	95.9	Very high	2 Å²	2	15.4 Å²	15.4	1%	0.012	8%	0.075	C	C	.	.	H	α-helix	trans	-64.1	-38.7	166.5	170	0	0	0	0	110.8	Q89 L90 A134 S135 T136 S141 L142 I167	Q89-V138 HydrophobicContact CB-CG1 4.35Å; L90-V138 HydrophobicContact CB-CG1 4.23Å; L90-V138 HydrophobicContact CD1-CG1 4.41Å; A134-V138 WeakPolarHBondContact O-CB 3.27Å; A134-V138 WeakPolarHBondContact O-CG2 3.39Å; A134-V138 PolarHBondContact O-N 2.58Å; S135-V138 PolarHBondContact O-N 3.47Å; T136-V138 VanDerWaalsContact C-N 3.33Å; T136-V138 PolarHBondContact O-N 3.33Å; V138-S141 PolarHBondContact O-N 3.46Å; V138-L142 WeakPolarHBondContact O-CB 3.45Å; V138-L142 PolarHBondContact O-N 3.47Å; V138-I167 HydrophobicContact CB-CD1 4.48Å; V138-I167 HydrophobicContact CG1-CD1 4.21Å; V138-I167 HydrophobicContact CG2-CD1 3.97Å
139	L	96.1	Very high	95.5	Very high	5 Å²	5	14.3 Å²	14.3	3%	0.026	7%	0.072	C	C	.	.	H	α-helix	trans	-67.5	-40.9	174.6	-64.3	-179.7	0	0	0	112.7	L90 S135 T136 Y137 S141 L142 S143 I226 I279 F283	L90-L139 HydrophobicContact CD1-CD2 4.5Å; L90-L139 HydrophobicContact CD2-CD2 4.19Å; S135-L139 WeakPolarHBondContact O-CG 3.36Å; S135-L139 PolarHBondContact O-N 2.94Å; T136-L139 WeakPolarHBondContact O-CB 3.42Å; T136-L139 PolarHBondContact O-N 2.92Å; T136-L139 VanDerWaalsContact O-N 3.07Å; Y137-L139 VanDerWaalsContact C-N 3.33Å; L139-S141 VanDerWaalsContact C-N 3.32Å; L139-S141 PolarHBondContact O-N 3.27Å; L139-L142 PolarHBondContact O-N 2.86Å; L139-S143 WeakPolarHBondContact O-CB 3.31Å; L139-S143 PolarHBondContact O-N 3.31Å; L139-S143 PolarHBondContact O-OG 3.29Å; L139-I226 HydrophobicContact CB-CD1 4.2Å; L139-I279 HydrophobicContact CD1-CG2 4.46Å; L139-I279 HydrophobicContact CD2-CG2 3.19Å; L139-I279 HydrophobicContact CG-CG2 4.44Å; L139-F283 HydrophobicContact CD1-CB 3.79Å; L139-F283 HydrophobicContact CD1-CD2 3.57Å; L139-F283 HydrophobicContact CD1-CE2 4.37Å; L139-F283 HydrophobicContact CD1-CG 3.79Å
140	V	97.7	Very high	95	Very high	16 Å²	16	13.5 Å²	13.5	10%	0.097	7%	0.067	C	C	.	.	H	α-helix	trans	-60.2	-45.9	172.3	175.7	0	0	0	0	110.2	T136 Y137 L142 S143 I144 P222 I225 I226	T136-V140 PolarHBondContact O-N 3.4Å; Y137-V140 PolarHBondContact O-N 3.01Å; V140-L142 PolarHBondContact O-N 3Å; V140-S143 WeakPolarHBondContact O-CA 3.44Å; V140-S143 VanDerWaalsContact O-CB 3.28Å; V140-S143 WeakPolarHBondContact O-CB 3.28Å; V140-S143 PolarHBondContact O-N 3.5Å; V140-I144 HydrophobicContact CG1-CD1 3.95Å; V140-I144 WeakPolarHBondContact O-CG1 3.32Å; V140-I144 PolarHBondContact O-N 2.92Å; V140-P222 HydrophobicContact CG2-CB 3.8Å; V140-I225 HydrophobicContact CG1-CG2 3.89Å; V140-I226 HydrophobicContact CG2-CD1 4.06Å; V140-I226 HydrophobicContact CG2-CG1 4.07Å
141	S	96.8	Very high	94.5	Very high	7 Å²	7	15.1 Å²	15.1	5%	0.049	8%	0.077	C	C	.	.	H	α-helix	trans	-61.7	-41.8	177.8	-63.3	0	0	0	0	112.6	Y137 V138 L139 S143 I144 D145 L166	Y137-S141 VanDerWaalsContact O-CB 3.32Å; Y137-S141 WeakPolarHBondContact O-CB 3.26Å; Y137-S141 PolarHBondContact O-N 2.85Å; Y137-S141 PolarHBondContact O-OG 3.27Å; V138-S141 PolarHBondContact O-N 3.46Å; L139-S141 VanDerWaalsContact C-N 3.32Å; L139-S141 PolarHBondContact O-N 3.27Å; S141-S143 VanDerWaalsContact C-N 3.28Å; S141-S143 PolarHBondContact O-N 2.88Å; S141-I144 PolarHBondContact O-N 3.24Å; S141-D145 WeakPolarHBondContact O-CB 3.5Å; S141-D145 PolarHBondContact O-N 3.29Å; S141-L166 PolarHBondContact OG-O 2.88Å
142	L	94.7	Very high	93.9	Very high	6 Å²	6	20.9 Å²	20.9	3%	0.031	10%	0.099	C	C	.	.	H	α-helix	trans	-59	-42.1	172.5	174.1	61.9	0	0	0	110.9	F86 V138 L139 V140 D145 R146 Y275	F86-L142 HydrophobicContact CB-CD1 4.04Å; F86-L142 HydrophobicContact CD1-CB 4.08Å; F86-L142 HydrophobicContact CD2-CD1 4.12Å; F86-L142 HydrophobicContact CE1-CB 4.5Å; F86-L142 HydrophobicContact CG-CB 4.36Å; F86-L142 HydrophobicContact CG-CD1 3.99Å; V138-L142 WeakPolarHBondContact O-CB 3.45Å; V138-L142 PolarHBondContact O-N 3.47Å; L139-L142 PolarHBondContact O-N 2.86Å; V140-L142 PolarHBondContact O-N 3Å; L142-D145 WeakPolarHBondContact O-CB 3.05Å; L142-D145 PolarHBondContact O-N 3.08Å; L142-R146 HydrophobicContact CD1-CG 4.43Å; L142-R146 VanDerWaalsContact O-CG 3.32Å; L142-R146 WeakPolarHBondContact O-CG 3.44Å; L142-R146 PolarHBondContact O-N 2.99Å; L142-Y275 HydrophobicContact CD2-CE1 4.42Å
143	S	95.1	Very high	93	Very high	0 Å²	0	22.4 Å²	22.4	0%	0	11%	0.11	C	C	.	.	H	α-helix	trans	-64.2	-46.9	179.7	-55.3	0	0	0	0	112.4	L139 V140 S141 D145 R146 Y147 Y230	L139-S143 WeakPolarHBondContact O-CB 3.31Å; L139-S143 PolarHBondContact O-N 3.31Å; L139-S143 PolarHBondContact O-OG 3.29Å; V140-S143 WeakPolarHBondContact O-CA 3.44Å; V140-S143 VanDerWaalsContact O-CB 3.28Å; V140-S143 WeakPolarHBondContact O-CB 3.28Å; V140-S143 PolarHBondContact O-N 3.5Å; S141-S143 VanDerWaalsContact C-N 3.28Å; S141-S143 PolarHBondContact O-N 2.88Å; S143-D145 VanDerWaalsContact C-N 3.33Å; S143-D145 PolarHBondContact O-N 2.69Å; S143-R146 PolarHBondContact O-N 3.11Å; S143-Y147 PolarHBondContact O-N 2.83Å; S143-Y230 WeakPolarHBondContact OG-CE2 3.36Å
144	I	94.6	Very high	91.5	Very high	42 Å²	42	31 Å²	31	22%	0.215	15%	0.153	C	C	.	.	H	α-helix	trans	-59.9	-45	173.9	-66.8	168.2	0	0	0	110.2	V140 S141 R146 Y147 H148 L166	V140-I144 HydrophobicContact CG1-CD1 3.95Å; V140-I144 WeakPolarHBondContact O-CG1 3.32Å; V140-I144 PolarHBondContact O-N 2.92Å; S141-I144 PolarHBondContact O-N 3.24Å; I144-R146 VanDerWaalsContact C-N 3.32Å; I144-R146 PolarHBondContact O-N 3.36Å; I144-Y147 WeakPolarHBondContact O-CB 3.37Å; I144-Y147 PolarHBondContact O-N 2.86Å; I144-H148 PolarHBondContact O-CD2 3.02Å; I144-H148 VanDerWaalsContact O-CD2 3.24Å; I144-H148 PolarHBondContact O-N 3Å; I144-L166 HydrophobicContact CB-CD1 4.31Å; I144-L166 HydrophobicContact CD1-CD2 4.41Å; I144-L166 HydrophobicContact CG2-CD1 3.89Å; I144-L166 HydrophobicContact CG2-CD2 4.14Å
145	D	92.5	Very high	90.1	Very high	0 Å²	0	37.6 Å²	37.6	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-60.4	-41.2	177.9	-179.7	78.2	0	0	0	112.5	R82 F86 S141 L142 S143 A149	R82-D145 WeakPolarHBondContact CD-OD1 3.42Å; R82-D145 VanDerWaalsContact CZ-CG 3.41Å; R82-D145 IonicContact CZ-OD1 2.87Å; R82-D145 IonicContact CZ-OD2 3.32Å; R82-D145 VanDerWaalsContact NE-CG 3.25Å; R82-D145 IonicContact NE-OD1 2.89Å; R82-D145 PolarHBondContact NE-OD1 3.39Å; R82-D145 IonicContact NE-OD2 2.85Å; R82-D145 PolarHBondContact NE-OD2 3.37Å; R82-D145 IonicContact NH1-OD1 3.19Å; R82-D145 PolarHBondContact NH1-OD1 3.45Å; R82-D145 VanDerWaalsContact NH2-CG 3.29Å; R82-D145 PolarHBondContact NH2-O 3.2Å; R82-D145 VanDerWaalsContact NH2-O 3.15Å; R82-D145 IonicContact NH2-OD1 3.55Å; R82-D145 PolarHBondContact NH2-OD1 2.93Å; R82-D145 VanDerWaalsContact NH2-OD1 3.15Å; R82-D145 IonicContact NH2-OD2 3.53Å; R82-D145 PolarHBondContact NH2-OD2 3.4Å; F86-D145 HydrophobicContact CE2-CB 3.6Å; F86-D145 VanDerWaalsContact CE2-CG 3.48Å; F86-D145 HydrophobicContact CZ-CB 3.68Å; S141-D145 WeakPolarHBondContact O-CB 3.5Å; S141-D145 PolarHBondContact O-N 3.29Å; L142-D145 WeakPolarHBondContact O-CB 3.05Å; L142-D145 PolarHBondContact O-N 3.08Å; S143-D145 VanDerWaalsContact C-N 3.33Å; S143-D145 PolarHBondContact O-N 2.69Å; D145-A149 WeakPolarHBondContact O-CB 3.49Å; D145-A149 PolarHBondContact O-N 3.49Å
146	R	91.4	Very high	88.4	Confident	11 Å²	11	43.8 Å²	43.8	4%	0.042	21%	0.208	C	C	.	.	H	α-helix	trans	-64.2	-44.8	175	-69.5	-50.7	86.4	172.7	10.8	111.7	L142 S143 I144 H148 A149 I150 Y230	L142-R146 HydrophobicContact CD1-CG 4.43Å; L142-R146 VanDerWaalsContact O-CG 3.32Å; L142-R146 WeakPolarHBondContact O-CG 3.44Å; L142-R146 PolarHBondContact O-N 2.99Å; S143-R146 PolarHBondContact O-N 3.11Å; I144-R146 VanDerWaalsContact C-N 3.32Å; I144-R146 PolarHBondContact O-N 3.36Å; R146-H148 PolarHBondContact O-N 2.82Å; R146-A149 WeakPolarHBondContact O-CB 3.45Å; R146-A149 PolarHBondContact O-N 3.12Å; R146-I150 WeakPolarHBondContact O-CG1 3.18Å; R146-I150 PolarHBondContact O-N 3.12Å; R146-Y230 WeakPolarHBondContact CG-OH 3.47Å
147	Y	92.3	Very high	86.8	Confident	44 Å²	44	51.3 Å²	51.3	17%	0.173	25%	0.247	C	C	.	.	H	α-helix	trans	-53.7	-54.7	175.1	168.8	-97.8	0	0	0	111.4	S143 I144 A149 I150 V151 Y152 M229 I232	S143-Y147 PolarHBondContact O-N 2.83Å; I144-Y147 WeakPolarHBondContact O-CB 3.37Å; I144-Y147 PolarHBondContact O-N 2.86Å; Y147-A149 VanDerWaalsContact C-N 3.32Å; Y147-A149 PolarHBondContact O-N 3.16Å; Y147-I150 PolarHBondContact O-N 3.38Å; Y147-V151 HydrophobicContact CD2-CG2 3.8Å; Y147-V151 HydrophobicContact CE2-CB 4.36Å; Y147-V151 HydrophobicContact CE2-CG2 3.65Å; Y147-V151 HydrophobicContact CG-CG2 4.47Å; Y147-V151 WeakPolarHBondContact O-CB 3.24Å; Y147-V151 WeakPolarHBondContact O-CG2 3.43Å; Y147-V151 PolarHBondContact O-N 3.13Å; Y147-Y152 HydrophobicContact CE1-CE2 4.09Å; Y147-M229 HydrophobicContact CD1-SD 4.15Å; Y147-M229 HydrophobicContact CD2-SD 3.99Å; Y147-M229 HydrophobicContact CG-SD 3.77Å; Y147-I232 HydrophobicContact CD2-CB 4.33Å; Y147-I232 HydrophobicContact CD2-CG2 4.11Å; Y147-I232 HydrophobicContact CE2-CB 4.25Å; Y147-I232 HydrophobicContact CE2-CD1 4.13Å; Y147-I232 HydrophobicContact CE2-CG2 3.71Å
148	H	90.6	Very high	85.6	Confident	59 Å²	59	55.5 Å²	55.5	27%	0.273	27%	0.268	S	S	.	.	H	α-helix	trans	-63.1	-35.9	178.8	-76.1	-77.2	0	0	0	113.2	I144 R146 I150 Y152 Q162	I144-H148 PolarHBondContact O-CD2 3.02Å; I144-H148 VanDerWaalsContact O-CD2 3.24Å; I144-H148 PolarHBondContact O-N 3Å; R146-H148 PolarHBondContact O-N 2.82Å; H148-I150 PolarHBondContact O-N 3.35Å; H148-Y152 AromaticContact ND1-CD2 3.84Å; H148-Y152 CarbonylContact O-C 3.24Å; H148-Y152 PolarHBondContact O-N 3.46Å; H148-Q162 PolarHBondContact CD2-NE2 3.45Å; H148-Q162 PolarHBondContact NE2-NE2 2.96Å
149	A	88.6	Confident	84.9	Confident	11 Å²	11	55.6 Å²	55.6	9%	0.091	27%	0.269	C	S	.	.	H	α-helix	trans	-60.1	-29.6	179.4	0	0	0	0	0	114.4	D145 R146 Y147 K269	D145-A149 WeakPolarHBondContact O-CB 3.49Å; D145-A149 PolarHBondContact O-N 3.49Å; R146-A149 WeakPolarHBondContact O-CB 3.45Å; R146-A149 PolarHBondContact O-N 3.12Å; Y147-A149 VanDerWaalsContact C-N 3.32Å; Y147-A149 PolarHBondContact O-N 3.16Å; A149-K269 PolarHBondContact O-NZ 3.36Å
150	I	87.6	Confident	84.4	Confident	6 Å²	6	60 Å²	60	3%	0.031	29%	0.289	C	S	.	.	H	α-helix	trans	-104.9	-42.1	-170.4	-61.2	-57.3	0	0	0	111.4	R146 Y147 H148 V233 T236 I237 K240 I265 K269 I273	R146-I150 WeakPolarHBondContact O-CG1 3.18Å; R146-I150 PolarHBondContact O-N 3.12Å; Y147-I150 PolarHBondContact O-N 3.38Å; H148-I150 PolarHBondContact O-N 3.35Å; I150-V233 HydrophobicContact CG1-CG1 4.45Å; I150-T236 HydrophobicContact CG2-CG2 3.85Å; I150-I237 HydrophobicContact CG2-CG1 4.13Å; I150-K240 PolarHBondContact O-NZ 3.25Å; I150-I265 HydrophobicContact CD1-CG2 4.38Å; I150-K269 HydrophobicContact CD1-CD 4.43Å; I150-I273 HydrophobicContact CD1-CD1 3.71Å; I150-I273 HydrophobicContact CG1-CD1 4.08Å
151	V	87.5	Confident	84	Confident	37 Å²	37	67 Å²	67	22%	0.224	32%	0.319	C	S	.	.	H	α-helix	trans	-77.4	-40.9	179.9	-176.8	0	0	0	0	110.9	Y147 P153 I232 T236	Y147-V151 HydrophobicContact CD2-CG2 3.8Å; Y147-V151 HydrophobicContact CE2-CB 4.36Å; Y147-V151 HydrophobicContact CE2-CG2 3.65Å; Y147-V151 HydrophobicContact CG-CG2 4.47Å; Y147-V151 WeakPolarHBondContact O-CB 3.24Å; Y147-V151 WeakPolarHBondContact O-CG2 3.43Å; Y147-V151 PolarHBondContact O-N 3.13Å; V151-P153 VanDerWaalsContact C-CD 3.47Å; V151-P153 VanDerWaalsContact O-CD 3.28Å; V151-P153 WeakPolarHBondContact O-CD 3.27Å; V151-I232 HydrophobicContact CG2-CG2 4.37Å; V151-T236 HydrophobicContact CG2-CG2 4.46Å
152	Y	85	Confident	83.7	Confident	129 Å²	129	69.4 Å²	69.4	51%	0.506	33%	0.329	S	S	.	.			trans	-123.6	65.3	-174.5	-56.7	-72.7	0	0	0	113	Y147 H148 M154	Y147-Y152 HydrophobicContact CE1-CE2 4.09Å; H148-Y152 AromaticContact ND1-CD2 3.84Å; H148-Y152 CarbonylContact O-C 3.24Å; H148-Y152 PolarHBondContact O-N 3.46Å; Y152-M154 VanDerWaalsContact C-N 3.27Å; Y152-M154 PolarHBondContact O-N 3.26Å
153	P	78	Confident	83.6	Confident	60 Å²	60	69.2 Å²	69.2	39%	0.39	33%	0.328	S	S	.	.	G	3₁₀ helix	trans	-66.7	-21.5	-171.8	27.5	-36	0	0	0	114.8	V151 K155	V151-P153 VanDerWaalsContact C-CD 3.47Å; V151-P153 VanDerWaalsContact O-CD 3.28Å; V151-P153 WeakPolarHBondContact O-CD 3.27Å; P153-K155 PolarHBondContact O-N 2.88Å; P153-K155 VanDerWaalsContact O-N 3.15Å
154	M	66	Low	83.6	Confident	186 Å²	186	76.9 Å²	76.9	92%	0.916	36%	0.357	S	S	*	.	G	3₁₀ helix	trans	-72.4	-4.5	-171	-64.3	-169.9	-75	0	0	114.6	Y152	Y152-M154 VanDerWaalsContact C-N 3.27Å; Y152-M154 PolarHBondContact O-N 3.26Å
155	K	68.8	Low	83.6	Confident	137 Å²	137	78.9 Å²	78.9	60%	0.596	37%	0.371	S	S	*	.	G	3₁₀ helix	trans	-112.3	37.5	-176.4	-70.9	174.6	167.2	-171.8	0	113.3	P153 L157 Q158 G159	P153-K155 PolarHBondContact O-N 2.88Å; P153-K155 VanDerWaalsContact O-N 3.15Å; K155-L157 PolarHBondContact O-N 3.38Å; K155-Q158 HydrophobicContact CB-CB 4.35Å; K155-Q158 WeakPolarHBondContact O-CB 3.49Å; K155-Q158 PolarHBondContact O-N 2.93Å; K155-G159 PolarHBondContact O-N 3.42Å
156	F	61.5	Low	83.8	Confident	136 Å²	136	80 Å²	80	60%	0.596	38%	0.377	S	S	*	.	H	α-helix	trans	-54.6	-44.8	-171.5	-176.1	-99.7	0	0	0	114.6	Q158 G159	F156-Q158 VanDerWaalsContact C-N 3.28Å; F156-Q158 PolarHBondContact O-N 3.47Å; F156-G159 WeakPolarHBondContact O-CA 3.27Å; F156-G159 PolarHBondContact O-N 3.3Å
157	L	62.3	Low	84.1	Confident	157 Å²	157	79.9 Å²	79.9	82%	0.822	38%	0.377	S	S	*	.	H	α-helix	trans	-63.1	-32.1	178.4	-75	161.9	0	0	0	112.9	K155 G159	K155-L157 PolarHBondContact O-N 3.38Å; L157-G159 PolarHBondContact O-N 3.15Å
158	Q	73.2	Confident	84.4	Confident	115 Å²	115	82.1 Å²	82.1	54%	0.537	40%	0.395	S	S	.	.	H	α-helix	trans	-71.4	-21.3	173.9	-64.4	-179.7	-28.6	0	0	111.6	K155 F156 E160 K161 Q162	K155-Q158 HydrophobicContact CB-CB 4.35Å; K155-Q158 WeakPolarHBondContact O-CB 3.49Å; K155-Q158 PolarHBondContact O-N 2.93Å; F156-Q158 VanDerWaalsContact C-N 3.28Å; F156-Q158 PolarHBondContact O-N 3.47Å; Q158-E160 PolarHBondContact O-N 3.4Å; Q158-K161 PolarHBondContact O-N 3.25Å; Q158-Q162 VanDerWaalsContact O-CB 3.3Å; Q158-Q162 WeakPolarHBondContact O-CB 3.43Å; Q158-Q162 PolarHBondContact O-N 3Å
159	G	81.5	Confident	84.7	Confident	3 Å²	3	83.4 Å²	83.4	3%	0.031	40%	0.403	C	S	.	.	H	α-helix	trans	-64.2	-31.9	-177.4	0	0	0	0	0	114.7	R82 K155 F156 L157 A163	R82-G159 WeakPolarHBondContact CD-O 3.46Å; K155-G159 PolarHBondContact O-N 3.42Å; F156-G159 WeakPolarHBondContact O-CA 3.27Å; F156-G159 PolarHBondContact O-N 3.3Å; L157-G159 PolarHBondContact O-N 3.15Å; G159-A163 WeakPolarHBondContact O-CB 3.35Å; G159-A163 PolarHBondContact O-N 3.25Å
160	E	86	Confident	85.2	Confident	98 Å²	98	83 Å²	83	46%	0.458	40%	0.4	S	S	.	.	H	α-helix	trans	-74.6	-44.2	177.1	-67.1	-167.6	172	0	0	112.2	Q158 Q162 A163 R164	Q158-E160 PolarHBondContact O-N 3.4Å; E160-Q162 VanDerWaalsContact C-N 3.32Å; E160-A163 PolarHBondContact O-N 3.08Å; E160-R164 WeakPolarHBondContact O-CG 3.34Å; E160-R164 PolarHBondContact O-N 3.48Å; E160-R164 VanDerWaalsContact O-N 3.14Å
161	K	89.4	Confident	85.7	Confident	164 Å²	164	85 Å²	85	71%	0.713	41%	0.407	S	S	*	.	H	α-helix	trans	-60.8	-45	174.7	-68.6	-174.5	-179.9	-177.6	0	110.4	Q158 A163 R164 V165	Q158-K161 PolarHBondContact O-N 3.25Å; K161-A163 PolarHBondContact O-N 3.46Å; K161-R164 PolarHBondContact O-N 2.81Å; K161-V165 WeakPolarHBondContact O-CG2 3.28Å; K161-V165 PolarHBondContact O-N 3.04Å
162	Q	91	Very high	86.2	Confident	57 Å²	57	86.5 Å²	86.5	27%	0.266	42%	0.419	S	S	.	.	H	α-helix	trans	-58.4	-47.3	176.1	-175.8	179.7	5.9	0	0	111.9	H148 Q158 E160 R164 V165 L166	H148-Q162 PolarHBondContact CD2-NE2 3.45Å; H148-Q162 PolarHBondContact NE2-NE2 2.96Å; Q158-Q162 VanDerWaalsContact O-CB 3.3Å; Q158-Q162 WeakPolarHBondContact O-CB 3.43Å; Q158-Q162 PolarHBondContact O-N 3Å; E160-Q162 VanDerWaalsContact C-N 3.32Å; Q162-R164 VanDerWaalsContact C-N 3.29Å; Q162-R164 PolarHBondContact O-N 2.98Å; Q162-V165 PolarHBondContact O-N 3.26Å; Q162-L166 HydrophobicContact CG-CD1 4.1Å; Q162-L166 HydrophobicContact CG-CG 4.33Å; Q162-L166 WeakPolarHBondContact O-CG 3.15Å; Q162-L166 PolarHBondContact O-N 3.23Å
163	A	92.8	Very high	86.8	Confident	1 Å²	1	83.4 Å²	83.4	1%	0.008	41%	0.411	C	S	.	.	H	α-helix	trans	-59	-40.3	178.6	0	0	0	0	0	112.5	R82 F85 F86 G159 E160 K161 I167	R82-A163 HydrophobicContact CG-CB 3.93Å; F85-A163 HydrophobicContact CD1-CB 4.26Å; F85-A163 HydrophobicContact CE1-CB 4.32Å; F86-A163 HydrophobicContact CE2-CB 3.78Å; F86-A163 HydrophobicContact CZ-CB 3.9Å; G159-A163 WeakPolarHBondContact O-CB 3.35Å; G159-A163 PolarHBondContact O-N 3.25Å; E160-A163 PolarHBondContact O-N 3.08Å; K161-A163 PolarHBondContact O-N 3.46Å; A163-I167 WeakPolarHBondContact O-CG1 3.5Å; A163-I167 PolarHBondContact O-N 3.5Å; A163-I167 VanDerWaalsContact O-N 3.15Å
164	R	94.5	Very high	87.8	Confident	161 Å²	161	80.5 Å²	80.5	61%	0.608	39%	0.392	S	S	*	.	H	α-helix	trans	-65.1	-45.1	175.4	-66.8	-179.7	-169.1	-133.3	6.4	112	F85 E160 K161 Q162 L166 I167 V168	F85-R164 HydrophobicContact CE1-CG 4.4Å; F85-R164 HydrophobicContact CZ-CG 4.06Å; E160-R164 WeakPolarHBondContact O-CG 3.34Å; E160-R164 PolarHBondContact O-N 3.48Å; E160-R164 VanDerWaalsContact O-N 3.14Å; K161-R164 PolarHBondContact O-N 2.81Å; Q162-R164 VanDerWaalsContact C-N 3.29Å; Q162-R164 PolarHBondContact O-N 2.98Å; R164-L166 VanDerWaalsContact C-N 3.34Å; R164-L166 PolarHBondContact O-N 3.21Å; R164-I167 PolarHBondContact O-N 3.19Å; R164-V168 WeakPolarHBondContact O-CG2 3.48Å; R164-V168 PolarHBondContact O-N 2.72Å
165	V	95.7	Very high	89.4	Confident	84 Å²	84	75.7 Å²	75.7	51%	0.509	37%	0.366	S	S	.	.	H	α-helix	trans	-60.2	-44.6	177.3	170.9	0	0	0	0	111	K161 Q162 I167 V168 I169	K161-V165 WeakPolarHBondContact O-CG2 3.28Å; K161-V165 PolarHBondContact O-N 3.04Å; Q162-V165 PolarHBondContact O-N 3.26Å; V165-I167 VanDerWaalsContact C-N 3.34Å; V165-I167 PolarHBondContact O-N 3.41Å; V165-V168 PolarHBondContact O-N 3.36Å; V165-I169 HydrophobicContact CG1-CD1 3.76Å; V165-I169 HydrophobicContact CG1-CG1 4.4Å; V165-I169 VanDerWaalsContact O-CG1 3.31Å; V165-I169 WeakPolarHBondContact O-CG1 3.34Å; V165-I169 PolarHBondContact O-N 3.06Å
166	L	96.4	Very high	90.8	Very high	25 Å²	25	73.8 Å²	73.8	13%	0.131	36%	0.362	C	S	.	.	H	α-helix	trans	-59.7	-43.3	177.6	-70.3	172.3	0	0	0	112.1	S141 I144 Q162 R164 I169 A170	S141-L166 PolarHBondContact OG-O 2.88Å; I144-L166 HydrophobicContact CB-CD1 4.31Å; I144-L166 HydrophobicContact CD1-CD2 4.41Å; I144-L166 HydrophobicContact CG2-CD1 3.89Å; I144-L166 HydrophobicContact CG2-CD2 4.14Å; Q162-L166 HydrophobicContact CG-CD1 4.1Å; Q162-L166 HydrophobicContact CG-CG 4.33Å; Q162-L166 WeakPolarHBondContact O-CG 3.15Å; Q162-L166 PolarHBondContact O-N 3.23Å; R164-L166 VanDerWaalsContact C-N 3.34Å; R164-L166 PolarHBondContact O-N 3.21Å; L166-I169 PolarHBondContact O-N 3.07Å; L166-A170 WeakPolarHBondContact O-CB 3.14Å; L166-A170 PolarHBondContact O-N 3.46Å
167	I	97.5	Very high	92.5	Very high	8 Å²	8	70.9 Å²	70.9	4%	0.041	35%	0.349	C	S	.	.	H	α-helix	trans	-65.9	-41.9	176.9	-69.3	-62.1	0	0	0	111.7	F85 F86 Q89 V138 A163 R164 V165 I169 A170 W171	F85-I167 HydrophobicContact CD1-CG1 4.5Å; F85-I167 HydrophobicContact CE1-CB 4.25Å; F85-I167 HydrophobicContact CE1-CG1 3.58Å; F85-I167 HydrophobicContact CZ-CB 4.31Å; F85-I167 HydrophobicContact CZ-CG1 4.06Å; F85-I167 HydrophobicContact CZ-CG2 4.46Å; F86-I167 HydrophobicContact CD1-CD1 3.78Å; F86-I167 HydrophobicContact CD1-CG1 4.35Å; F86-I167 HydrophobicContact CE1-CD1 3.64Å; F86-I167 HydrophobicContact CE1-CG1 3.96Å; Q89-I167 HydrophobicContact CB-CD1 4.16Å; Q89-I167 HydrophobicContact CG-CD1 4.08Å; Q89-I167 HydrophobicContact CG-CG1 4.16Å; Q89-I167 HydrophobicContact CG-CG2 3.97Å; V138-I167 HydrophobicContact CB-CD1 4.48Å; V138-I167 HydrophobicContact CG1-CD1 4.21Å; V138-I167 HydrophobicContact CG2-CD1 3.97Å; A163-I167 WeakPolarHBondContact O-CG1 3.5Å; A163-I167 PolarHBondContact O-N 3.5Å; A163-I167 VanDerWaalsContact O-N 3.15Å; R164-I167 PolarHBondContact O-N 3.19Å; V165-I167 VanDerWaalsContact C-N 3.34Å; V165-I167 PolarHBondContact O-N 3.41Å; I167-I169 VanDerWaalsContact C-N 3.33Å; I167-I169 PolarHBondContact O-N 3.22Å; I167-A170 WeakPolarHBondContact O-CB 3.47Å; I167-A170 PolarHBondContact O-N 2.9Å; I167-W171 VanDerWaalsContact O-CD1 3.29Å; I167-W171 PolarHBondContact O-N 2.97Å
168	V	97.7	Very high	94.2	Very high	91 Å²	91	63.4 Å²	63.4	55%	0.552	31%	0.31	S	S	*	.	H	α-helix	trans	-60	-46.1	175.5	171.4	0	0	0	0	110.4	R164 V165 A170 W171 S172	R164-V168 WeakPolarHBondContact O-CG2 3.48Å; R164-V168 PolarHBondContact O-N 2.72Å; V165-V168 PolarHBondContact O-N 3.36Å; V168-A170 PolarHBondContact O-N 3.31Å; V168-W171 PolarHBondContact O-N 2.87Å; V168-S172 WeakPolarHBondContact O-CB 3.42Å; V168-S172 PolarHBondContact O-N 3.4Å; V168-S172 PolarHBondContact O-OG 2.92Å
169	I	98.1	Very high	95.3	Very high	86 Å²	86	61.6 Å²	61.6	44%	0.441	30%	0.304	S	S	.	.	H	α-helix	trans	-59.4	-46.3	175.9	-68.1	167.1	0	0	0	110.8	V165 L166 I167 W171 S172 L173	V165-I169 HydrophobicContact CG1-CD1 3.76Å; V165-I169 HydrophobicContact CG1-CG1 4.4Å; V165-I169 VanDerWaalsContact O-CG1 3.31Å; V165-I169 WeakPolarHBondContact O-CG1 3.34Å; V165-I169 PolarHBondContact O-N 3.06Å; L166-I169 PolarHBondContact O-N 3.07Å; I167-I169 VanDerWaalsContact C-N 3.33Å; I167-I169 PolarHBondContact O-N 3.22Å; I169-W171 PolarHBondContact O-N 3.44Å; I169-S172 PolarHBondContact O-N 3.5Å; I169-L173 HydrophobicContact CG2-CD1 3.74Å; I169-L173 HydrophobicContact CG2-CG 4.2Å; I169-L173 WeakPolarHBondContact O-CB 3.13Å; I169-L173 VanDerWaalsContact O-CG 3.31Å; I169-L173 WeakPolarHBondContact O-CG 3.41Å; I169-L173 PolarHBondContact O-N 3.48Å
170	A	98.2	Very high	96	Very high	3 Å²	3	64.2 Å²	64.2	3%	0.025	32%	0.32	C	S	.	.	H	α-helix	trans	-55.7	-53.5	178.7	0	0	0	0	0	111.4	L166 I167 V168 L173 S174	L166-A170 WeakPolarHBondContact O-CB 3.14Å; L166-A170 PolarHBondContact O-N 3.46Å; I167-A170 WeakPolarHBondContact O-CB 3.47Å; I167-A170 PolarHBondContact O-N 2.9Å; V168-A170 PolarHBondContact O-N 3.31Å; A170-L173 PolarHBondContact O-N 2.94Å; A170-S174 PolarHBondContact O-N 2.94Å; A170-S174 PolarHBondContact O-OG 3.25Å
171	W	98.4	Very high	96.5	Very high	47 Å²	47	59.7 Å²	59.7	18%	0.178	30%	0.299	C	S	.	.	H	α-helix	trans	-63.2	-43	178.1	-81	96.2	0	0	0	112.8	T93 L131 A134 I167 V168 I169 L173 S174 F175	T93-W171 WeakPolarHBondContact OG1-CZ2 3.15Å; L131-W171 HydrophobicContact CD2-CH2 4.47Å; A134-W171 HydrophobicContact CB-CD2 4.44Å; A134-W171 HydrophobicContact CB-CE3 4.27Å; A134-W171 HydrophobicContact CB-CH2 4.37Å; A134-W171 HydrophobicContact CB-CZ3 4.24Å; I167-W171 VanDerWaalsContact O-CD1 3.29Å; I167-W171 PolarHBondContact O-N 2.97Å; V168-W171 PolarHBondContact O-N 2.87Å; I169-W171 PolarHBondContact O-N 3.44Å; W171-L173 VanDerWaalsContact C-N 3.35Å; W171-L173 PolarHBondContact O-N 3.25Å; W171-S174 WeakPolarHBondContact O-CB 3.45Å; W171-S174 PolarHBondContact O-N 2.87Å; W171-F175 HydrophobicContact CB-CE2 4.49Å; W171-F175 AromaticContact CE3-CE2 3.7Å; W171-F175 HydrophobicContact CE3-CE2 3.7Å; W171-F175 AromaticContact CE3-CZ 3.99Å; W171-F175 HydrophobicContact CE3-CZ 3.99Å; W171-F175 HydrophobicContact CZ3-CE2 4.39Å; W171-F175 HydrophobicContact CZ3-CZ 4.23Å; W171-F175 WeakPolarHBondContact O-CD2 3.44Å; W171-F175 PolarHBondContact O-N 3.38Å
172	S	98.4	Very high	96.7	Very high	69 Å²	69	54.6 Å²	54.6	48%	0.483	28%	0.279	S	S	.	.	H	α-helix	trans	-60.3	-43.8	177.9	-67.4	0	0	0	0	112	V168 I169 F175 L176	V168-S172 WeakPolarHBondContact O-CB 3.42Å; V168-S172 PolarHBondContact O-N 3.4Å; V168-S172 PolarHBondContact O-OG 2.92Å; I169-S172 PolarHBondContact O-N 3.5Å; S172-F175 PolarHBondContact O-N 3.45Å; S172-L176 VanDerWaalsContact O-CB 3.27Å; S172-L176 WeakPolarHBondContact O-CB 3.45Å; S172-L176 PolarHBondContact O-N 3.26Å
173	L	98.3	Very high	96.9	Very high	63 Å²	63	58 Å²	58	33%	0.33	30%	0.298	S	S	.	.	H	α-helix	trans	-65.7	-39.4	175.4	-70.6	175.1	0	0	0	111.7	Y137 I169 A170 W171 L176 F177	Y137-L173 HydrophobicContact CD2-CB 3.98Å; Y137-L173 HydrophobicContact CE2-CB 3.88Å; I169-L173 HydrophobicContact CG2-CD1 3.74Å; I169-L173 HydrophobicContact CG2-CG 4.2Å; I169-L173 WeakPolarHBondContact O-CB 3.13Å; I169-L173 VanDerWaalsContact O-CG 3.31Å; I169-L173 WeakPolarHBondContact O-CG 3.41Å; I169-L173 PolarHBondContact O-N 3.48Å; A170-L173 PolarHBondContact O-N 2.94Å; W171-L173 VanDerWaalsContact C-N 3.35Å; W171-L173 PolarHBondContact O-N 3.25Å; L173-L176 PolarHBondContact O-N 3.03Å; L173-F177 HydrophobicContact CB-CD2 4.46Å; L173-F177 HydrophobicContact CB-CE2 4.3Å; L173-F177 HydrophobicContact CD2-CE2 4.21Å; L173-F177 HydrophobicContact CD2-CZ 4.04Å; L173-F177 WeakPolarHBondContact O-CB 3.49Å; L173-F177 WeakPolarHBondContact O-CG 3.38Å; L173-F177 PolarHBondContact O-N 3.38Å
174	S	98.5	Very high	96.9	Very high	0 Å²	0	59.1 Å²	59.1	0%	0	30%	0.304	C	S	.	.	H	α-helix	trans	-61	-46.2	176.2	-58.7	0	0	0	0	112.4	Y133 A134 A170 W171 S178	Y133-S174 WeakPolarHBondContact CB-OG 3.31Å; Y133-S174 PolarHBondContact O-OG 3.47Å; A134-S174 WeakPolarHBondContact CA-OG 3.36Å; A134-S174 PolarHBondContact N-OG 3.36Å; A170-S174 PolarHBondContact O-N 2.94Å; A170-S174 PolarHBondContact O-OG 3.25Å; W171-S174 WeakPolarHBondContact O-CB 3.45Å; W171-S174 PolarHBondContact O-N 2.87Å; S174-S178 VanDerWaalsContact O-CB 3.28Å; S174-S178 WeakPolarHBondContact O-CB 3.46Å; S174-S178 PolarHBondContact O-N 3.04Å; S174-S178 PolarHBondContact O-OG 2.72Å
175	F	98.4	Very high	96.9	Very high	84 Å²	84	52.4 Å²	52.4	37%	0.368	28%	0.279	S	S	.	.	H	α-helix	trans	-62.7	-46.8	174.3	-74.3	-62.7	0	0	0	111.3	Y126 V130 W171 S172 S178 I179	Y126-F175 HydrophobicContact CE1-CD1 4.39Å; Y126-F175 PolarHBondContact OH-O 3.18Å; V130-F175 HydrophobicContact CB-CD1 4.44Å; V130-F175 HydrophobicContact CG1-CD1 3.7Å; V130-F175 HydrophobicContact CG1-CE1 3.58Å; V130-F175 HydrophobicContact CG1-CG 4.36Å; V130-F175 HydrophobicContact CG1-CZ 4.11Å; V130-F175 HydrophobicContact CG2-CD1 3.78Å; V130-F175 HydrophobicContact CG2-CE1 4.21Å; W171-F175 HydrophobicContact CB-CE2 4.49Å; W171-F175 AromaticContact CE3-CE2 3.7Å; W171-F175 HydrophobicContact CE3-CE2 3.7Å; W171-F175 AromaticContact CE3-CZ 3.99Å; W171-F175 HydrophobicContact CE3-CZ 3.99Å; W171-F175 HydrophobicContact CZ3-CE2 4.39Å; W171-F175 HydrophobicContact CZ3-CZ 4.23Å; W171-F175 WeakPolarHBondContact O-CD2 3.44Å; W171-F175 PolarHBondContact O-N 3.38Å; S172-F175 PolarHBondContact O-N 3.45Å; F175-S178 PolarHBondContact O-N 3.17Å; F175-I179 WeakPolarHBondContact O-CG1 3.4Å; F175-I179 PolarHBondContact O-N 3.3Å
176	L	98	Very high	96.9	Very high	97 Å²	97	48.4 Å²	48.4	51%	0.508	26%	0.255	S	S	.	.	H	α-helix	trans	-60.1	-52	-178.3	179.1	63.3	0	0	0	112.7	S172 L173 S178 I179	S172-L176 VanDerWaalsContact O-CB 3.27Å; S172-L176 WeakPolarHBondContact O-CB 3.45Å; S172-L176 PolarHBondContact O-N 3.26Å; L173-L176 PolarHBondContact O-N 3.03Å; L176-S178 PolarHBondContact O-N 3.31Å; L176-I179 HydrophobicContact CD1-CD1 4.13Å; L176-I179 WeakPolarHBondContact O-CB 3.46Å; L176-I179 WeakPolarHBondContact O-CG1 3.41Å; L176-I179 PolarHBondContact O-N 2.92Å
177	F	97.8	Very high	96.8	Very high	75 Å²	75	50.8 Å²	50.8	33%	0.329	26%	0.264	S	S	.	.	H	α-helix	trans	-72.7	-15.5	-177.6	-65.1	-26.8	0	0	0	113.6	Y133 Y137 L173 P180	Y133-F177 HydrophobicContact CE1-CB 4.37Å; Y133-F177 HydrophobicContact CE2-CB 4.28Å; Y137-F177 AromaticContact CE2-CD2 3.93Å; Y137-F177 HydrophobicContact CE2-CD2 3.93Å; Y137-F177 HydrophobicContact CE2-CE2 4.24Å; Y137-F177 WeakPolarHBondContact OH-CD2 3.35Å; L173-F177 HydrophobicContact CB-CD2 4.46Å; L173-F177 HydrophobicContact CB-CE2 4.3Å; L173-F177 HydrophobicContact CD2-CE2 4.21Å; L173-F177 HydrophobicContact CD2-CZ 4.04Å; L173-F177 WeakPolarHBondContact O-CB 3.49Å; L173-F177 WeakPolarHBondContact O-CG 3.38Å; L173-F177 PolarHBondContact O-N 3.38Å; F177-P180 WeakPolarHBondContact O-CD 3.5Å
178	S	97.7	Very high	96.5	Very high	0 Å²	0	55.9 Å²	55.9	0%	0	28%	0.283	C	S	.	.	H	α-helix	trans	-85.2	-13	175.2	-56.1	0	0	0	0	113.4	Y126 V130 Y133 S174 F175 L176 P180 T181	Y126-S178 VanDerWaalsContact CD2-O 3.22Å; Y126-S178 WeakPolarHBondContact CD2-O 3.27Å; Y126-S178 VanDerWaalsContact CE2-C 3.49Å; Y126-S178 VanDerWaalsContact CE2-CB 3.5Å; Y126-S178 WeakPolarHBondContact CE2-O 3.45Å; V130-S178 VanDerWaalsContact CA-OG 3.25Å; V130-S178 WeakPolarHBondContact CA-OG 3.35Å; V130-S178 VanDerWaalsContact CG2-CB 3.45Å; V130-S178 WeakPolarHBondContact CG2-OG 3.1Å; V130-S178 PolarHBondContact N-OG 3.16Å; Y133-S178 WeakPolarHBondContact CD2-OG 3.39Å; S174-S178 VanDerWaalsContact O-CB 3.28Å; S174-S178 WeakPolarHBondContact O-CB 3.46Å; S174-S178 PolarHBondContact O-N 3.04Å; S174-S178 PolarHBondContact O-OG 2.72Å; F175-S178 PolarHBondContact O-N 3.17Å; L176-S178 PolarHBondContact O-N 3.31Å; S178-P180 VanDerWaalsContact C-CD 3.42Å; S178-T181 WeakPolarHBondContact O-CB 3.42Å; S178-T181 PolarHBondContact O-N 3.36Å; S178-T181 PolarHBondContact O-OG1 2.86Å
179	I	97.4	Very high	96.1	Very high	78 Å²	78	56.4 Å²	56.4	40%	0.4	29%	0.286	S	S	.	.	H	α-helix	trans	-52.1	-44.3	-176.7	-68.2	175.9	0	0	0	113.3	F175 L176 T181 L182	F175-I179 WeakPolarHBondContact O-CG1 3.4Å; F175-I179 PolarHBondContact O-N 3.3Å; L176-I179 HydrophobicContact CD1-CD1 4.13Å; L176-I179 WeakPolarHBondContact O-CB 3.46Å; L176-I179 WeakPolarHBondContact O-CG1 3.41Å; L176-I179 PolarHBondContact O-N 2.92Å; I179-T181 PolarHBondContact O-N 3.02Å; I179-T181 VanDerWaalsContact O-N 3.1Å; I179-L182 WeakPolarHBondContact O-CB 3.49Å; I179-L182 PolarHBondContact O-N 2.92Å
180	P	95.9	Very high	95.5	Very high	58 Å²	58	55.9 Å²	55.9	38%	0.377	28%	0.284	S	S	.	.	H	α-helix	trans	-53.7	-34	179.5	-27.9	36.7	0	0	0	113.5	F177 S178 L182 I183 I184	F177-P180 WeakPolarHBondContact O-CD 3.5Å; S178-P180 VanDerWaalsContact C-CD 3.42Å; P180-L182 PolarHBondContact O-N 2.93Å; P180-I183 PolarHBondContact O-N 3.43Å; P180-I184 HydrophobicContact CB-CD1 3.85Å; P180-I184 WeakPolarHBondContact O-CD1 3.19Å; P180-I184 VanDerWaalsContact O-CG1 3.31Å; P180-I184 WeakPolarHBondContact O-CG1 3.42Å; P180-I184 PolarHBondContact O-N 2.91Å
181	T	95.4	Very high	94.8	Very high	2 Å²	2	61.8 Å²	61.8	1%	0.012	33%	0.325	C	S	.	.	H	α-helix	trans	-58.3	-33.4	178.7	-50.6	0	0	0	0	112.8	R125 V129 S178 I179 I183 F185 Y210	R125-T181 HydrophobicContact CB-CG2 3.97Å; V129-T181 HydrophobicContact CB-CG2 4.44Å; V129-T181 HydrophobicContact CG2-CG2 3.86Å; S178-T181 WeakPolarHBondContact O-CB 3.42Å; S178-T181 PolarHBondContact O-N 3.36Å; S178-T181 PolarHBondContact O-OG1 2.86Å; I179-T181 PolarHBondContact O-N 3.02Å; I179-T181 VanDerWaalsContact O-N 3.1Å; T181-I183 VanDerWaalsContact C-N 3.25Å; T181-I183 PolarHBondContact O-N 3.06Å; T181-F185 HydrophobicContact CG2-CD2 3.57Å; T181-F185 HydrophobicContact CG2-CE2 4.02Å; T181-F185 HydrophobicContact CG2-CG 4.29Å; T181-F185 WeakPolarHBondContact O-CB 3.26Å; T181-F185 PolarHBondContact O-N 3Å; T181-F185 VanDerWaalsContact O-N 3.09Å; T181-Y210 PolarHBondContact OG1-OH 3.21Å
182	L	95.4	Very high	94.3	Very high	58 Å²	58	64 Å²	64	30%	0.304	34%	0.341	S	S	.	.	H	α-helix	trans	-66.3	-28	177.6	-75.8	167.5	0	0	0	113.3	R122 Y126 I179 P180	R122-L182 HydrophobicContact CB-CD2 4.31Å; R122-L182 PolarHBondContact NH1-O 3.41Å; Y126-L182 VanDerWaalsContact CB-CD2 3.43Å; Y126-L182 HydrophobicContact CD1-CD1 4.2Å; Y126-L182 HydrophobicContact CD1-CD2 4.17Å; Y126-L182 HydrophobicContact CD1-CG 4.27Å; Y126-L182 HydrophobicContact CD2-CD1 3.7Å; Y126-L182 HydrophobicContact CD2-CD2 4.18Å; Y126-L182 HydrophobicContact CD2-CG 3.5Å; Y126-L182 HydrophobicContact CE1-CD1 4.31Å; Y126-L182 HydrophobicContact CE2-CD1 3.82Å; Y126-L182 HydrophobicContact CE2-CG 4.15Å; Y126-L182 HydrophobicContact CG-CD1 3.88Å; Y126-L182 HydrophobicContact CG-CD2 3.68Å; Y126-L182 HydrophobicContact CG-CG 3.55Å; I179-L182 WeakPolarHBondContact O-CB 3.49Å; I179-L182 PolarHBondContact O-N 2.92Å; P180-L182 PolarHBondContact O-N 2.93Å
183	I	93.9	Very high	93.7	Very high	129 Å²	129	63.5 Å²	63.5	66%	0.662	35%	0.346	S	S	*	.	H	α-helix	trans	-90.4	-42.5	-177	-57.2	172.3	0	0	0	109.6	P180 T181	P180-I183 PolarHBondContact O-N 3.43Å; T181-I183 VanDerWaalsContact C-N 3.25Å; T181-I183 PolarHBondContact O-N 3.06Å
184	I	94	Very high	93.2	Very high	23 Å²	23	64.6 Å²	64.6	12%	0.118	35%	0.349	C	S	.	.	H	α-helix	trans	-74.7	-43.7	-173.6	-66.7	160.4	0	0	0	112	P180 A199 L200 W201 Y210	P180-I184 HydrophobicContact CB-CD1 3.85Å; P180-I184 WeakPolarHBondContact O-CD1 3.19Å; P180-I184 VanDerWaalsContact O-CG1 3.31Å; P180-I184 WeakPolarHBondContact O-CG1 3.42Å; P180-I184 PolarHBondContact O-N 2.91Å; I184-A199 HydrophobicContact CG2-CB 3.78Å; I184-L200 PolarHBondContact O-N 3.39Å; I184-W201 HydrophobicContact CB-CH2 4.31Å; I184-W201 HydrophobicContact CB-CZ2 4.47Å; I184-W201 HydrophobicContact CD1-CH2 3.4Å; I184-W201 HydrophobicContact CD1-CZ2 4.05Å; I184-W201 HydrophobicContact CD1-CZ3 4.07Å; I184-W201 HydrophobicContact CG1-CH2 3.68Å; I184-W201 HydrophobicContact CG1-CZ2 4.3Å; I184-W201 HydrophobicContact CG1-CZ3 3.91Å; I184-W201 HydrophobicContact CG2-CD2 4.14Å; I184-W201 HydrophobicContact CG2-CE3 4.31Å; I184-W201 HydrophobicContact CG2-CH2 3.63Å; I184-W201 HydrophobicContact CG2-CZ2 3.38Å; I184-W201 HydrophobicContact CG2-CZ3 4.08Å; I184-Y210 HydrophobicContact CD1-CD2 3.89Å; I184-Y210 HydrophobicContact CD1-CE2 3.72Å
185	F	94.6	Very high	92.9	Very high	20 Å²	20	66.3 Å²	66.3	9%	0.088	36%	0.36	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-90.9	149.2	-174.5	-72.6	-99.3	0	0	0	111.9	R122 R125 T181 W198 A199 Y210	R122-F185 VanDerWaalsContact CG-O 3.32Å; R122-F185 WeakPolarHBondContact CG-O 3.46Å; R125-F185 HydrophobicContact CB-CB 4.07Å; R125-F185 HydrophobicContact CB-CG 4.25Å; R125-F185 HydrophobicContact CG-CB 4.06Å; R125-F185 HydrophobicContact CG-CD1 4.08Å; R125-F185 HydrophobicContact CG-CG 4.2Å; T181-F185 HydrophobicContact CG2-CD2 3.57Å; T181-F185 HydrophobicContact CG2-CE2 4.02Å; T181-F185 HydrophobicContact CG2-CG 4.29Å; T181-F185 WeakPolarHBondContact O-CB 3.26Å; T181-F185 PolarHBondContact O-N 3Å; T181-F185 VanDerWaalsContact O-N 3.09Å; F185-W198 WeakPolarHBondContact CA-O 3.26Å; F185-A199 HydrophobicContact CD1-CB 4.31Å; F185-A199 HydrophobicContact CE1-CB 4.06Å; F185-A199 HydrophobicContact CE2-CB 4.49Å; F185-A199 HydrophobicContact CZ-CB 4.15Å; F185-Y210 HydrophobicContact CE2-CE1 4.28Å
186	G	94.5	Very high	92.5	Very high	0 Å²	0	64.1 Å²	64.1	0%	0	35%	0.351	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-179.4	-177.5	178.7	0	0	0	0	0	112.1	D118 C121 C197 W198	D118-G186 WeakPolarHBondContact OD1-CA 3.12Å; C121-G186 VanDerWaalsContact SG-CA 3.51Å; G186-C197 CarbonylContact O-C 3.44Å; G186-C197 WeakPolarHBondContact O-CA 3.42Å; G186-W198 PolarHBondContact N-O 3.01Å; G186-W198 PolarHBondContact O-N 3.48Å
187	K	94.3	Very high	92.3	Very high	76 Å²	76	59.8 Å²	59.8	33%	0.33	33%	0.328	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-81.8	124.1	-178.7	-172.1	171.9	-173.4	167.8	0	110.4	F114 A116 D118 V195 Q196	F114-K187 HydrophobicContact CD1-CD 4.11Å; F114-K187 HydrophobicContact CD1-CG 4.14Å; F114-K187 HydrophobicContact CE1-CD 4.32Å; A116-K187 PolarHBondContact O-NZ 3.32Å; D118-K187 HydrophobicContact CB-CB 3.94Å; D118-K187 WeakPolarHBondContact OD1-CB 3.44Å; D118-K187 PolarHBondContact OD1-N 2.98Å; K187-V195 HydrophobicContact CD-CG1 4.13Å; K187-V195 HydrophobicContact CG-CG1 3.81Å; K187-Q196 CarbonylContact C-O 3.58Å; K187-Q196 WeakPolarHBondContact CA-O 3.48Å
188	R	91	Very high	92	Very high	114 Å²	114	62 Å²	62	43%	0.43	33%	0.334	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-132.3	138.9	179.6	171.8	176.7	175.3	178.4	-0.8	110.4	Q196	R188-Q196 PolarHBondContact N-O 3.27Å; R188-Q196 PolarHBondContact O-N 2.89Å
189	T	89.5	Confident	91.8	Very high	102 Å²	102	62 Å²	62	63%	0.626	34%	0.335	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-87.1	126.9	167.3	49.4	0	0	0	0	109.4	E194 V195	T189-E194 WeakPolarHBondContact CA-O 3.04Å; T189-V195 HydrophobicContact CG2-CG2 4.06Å
190	L	86	Confident	91.5	Very high	76 Å²	76	62.2 Å²	62.2	40%	0.398	34%	0.336	S	S	.	.			trans	-82.5	163.6	175	-170.9	62.1	0	0	0	110.2	N192 G193 E194	L190-N192 VanDerWaalsContact CB-OD1 3.26Å; L190-N192 WeakPolarHBondContact CB-OD1 3.41Å; L190-N192 WeakPolarHBondContact CD2-OD1 3.47Å; L190-N192 WeakPolarHBondContact CG-OD1 3.32Å; L190-N192 PolarHBondContact O-N 3.31Å; L190-G193 PolarHBondContact O-N 3.29Å; L190-E194 PolarHBondContact N-O 3.48Å
191	S	84.3	Confident	91.2	Very high	126 Å²	126	61.7 Å²	61.7	88%	0.881	33%	0.327	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.1	-25.1	-177.6	48.7	0	0	0	0	114	G193	S191-G193 PolarHBondContact O-N 2.81Å
192	N	86.2	Confident	90.8	Very high	95 Å²	95	66.5 Å²	66.5	51%	0.508	36%	0.358	S	S	.	.	T	Hydrogen-bonded Turn	trans	-79.4	-0.8	174.1	65	-8.5	0	0	0	113.6	L190 E194	L190-N192 VanDerWaalsContact CB-OD1 3.26Å; L190-N192 WeakPolarHBondContact CB-OD1 3.41Å; L190-N192 WeakPolarHBondContact CD2-OD1 3.47Å; L190-N192 WeakPolarHBondContact CG-OD1 3.32Å; L190-N192 PolarHBondContact O-N 3.31Å; N192-E194 PolarHBondContact ND2-OE2 2.81Å; N192-E194 WeakPolarHBondContact OD1-CB 3.23Å; N192-E194 PolarHBondContact OD1-N 3.44Å; N192-E194 VanDerWaalsContact OD1-N 3.12Å
193	G	86.6	Confident	90.5	Very high	58 Å²	58	68.2 Å²	68.2	60%	0.598	37%	0.368	S	S	*	.	S	Bend	trans	89.9	-7.8	-178.8	0	0	0	0	0	114.9	L190 S191	L190-G193 PolarHBondContact O-N 3.29Å; S191-G193 PolarHBondContact O-N 2.81Å
194	E	88.1	Confident	90.1	Very high	86 Å²	86	68.7 Å²	68.7	40%	0.402	37%	0.371	S	S	.	.			trans	-69.9	145.7	178	-68.1	177.6	163.3	0	0	111.4	D113 T189 L190 N192	D113-E194 WeakPolarHBondContact OD1-CA 3.34Å; D113-E194 WeakPolarHBondContact OD1-CB 3.47Å; T189-E194 WeakPolarHBondContact CA-O 3.04Å; L190-E194 PolarHBondContact N-O 3.48Å; N192-E194 PolarHBondContact ND2-OE2 2.81Å; N192-E194 WeakPolarHBondContact OD1-CB 3.23Å; N192-E194 PolarHBondContact OD1-N 3.44Å; N192-E194 VanDerWaalsContact OD1-N 3.12Å
195	V	91.4	Very high	89.9	Confident	35 Å²	35	71.5 Å²	71.5	21%	0.212	39%	0.393	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-108.4	117	-176.6	-178.2	0	0	0	0	109	D113 F114 K187 T189	D113-V195 PolarHBondContact OD1-N 3.28Å; D113-V195 VanDerWaalsContact OD1-N 3.15Å; F114-V195 VanDerWaalsContact CB-O 3.32Å; F114-V195 WeakPolarHBondContact CB-O 3.48Å; F114-V195 PolarHBondContact N-O 3.17Å; F114-V195 WeakPolarHBondContact O-CG1 3.47Å; K187-V195 HydrophobicContact CD-CG1 4.13Å; K187-V195 HydrophobicContact CG-CG1 3.81Å; T189-V195 HydrophobicContact CG2-CG2 4.06Å
196	Q	91.6	Very high	89.8	Confident	39 Å²	39	75.9 Å²	75.9	18%	0.182	41%	0.41	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-126.5	161.3	-171.7	-56.1	-71.1	-51.2	0	0	111.6	W108 G112 K187 R188	W108-Q196 HydrophobicContact CH2-CB 4.28Å; W108-Q196 HydrophobicContact CZ2-CB 4.3Å; G112-Q196 PolarHBondContact O-NE2 3.05Å; K187-Q196 CarbonylContact C-O 3.58Å; K187-Q196 WeakPolarHBondContact CA-O 3.48Å; R188-Q196 PolarHBondContact N-O 3.27Å; R188-Q196 PolarHBondContact O-N 2.89Å
197	C	93.2	Very high	89.7	Confident	5 Å²	5	79 Å²	79	3%	0.034	42%	0.421	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-114.2	88.2	-177.5	169.8	0	0	0	0	105.4	W108 F114 C121 R125 G186	W108-C197 HydrophobicContact CH2-CB 3.63Å; W108-C197 HydrophobicContact CZ3-CB 3.63Å; F114-C197 HydrophobicContact CB-CB 4.5Å; F114-C197 HydrophobicContact CD1-CB 4.16Å; F114-C197 HydrophobicContact CD2-CB 4.25Å; F114-C197 HydrophobicContact CE1-CB 4.47Å; F114-C197 HydrophobicContact CE2-CB 4.5Å; F114-C197 HydrophobicContact CG-CB 4.03Å; C121-C197 VanDerWaalsContact CA-SG 3.53Å; C121-C197 HydrophobicContact CB-CB 3.83Å; C121-C197 WeakPolarHBondContact CB-SG 3.23Å; C121-C197 VanDerWaalsContact SG-CA 3.51Å; C121-C197 WeakPolarHBondContact SG-CB 3.14Å; C121-C197 CovalentContact SG-SG 2.02Å; C121-C197 PolarHBondContact SG-SG 3.18Å; R125-C197 PolarHBondContact NE-O 3.22Å; R125-C197 PolarHBondContact NH2-O 3.06Å; G186-C197 CarbonylContact O-C 3.44Å; G186-C197 WeakPolarHBondContact O-CA 3.42Å
198	W	91.4	Very high	89.7	Confident	122 Å²	122	77.1 Å²	77.1	46%	0.462	42%	0.417	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-133	172	-166.8	-161.3	-105.2	0	0	0	110.6	F185 G186 W207	F185-W198 WeakPolarHBondContact CA-O 3.26Å; G186-W198 PolarHBondContact N-O 3.01Å; G186-W198 PolarHBondContact O-N 3.48Å; W198-W207 HydrophobicContact CH2-CH2 4.19Å; W198-W207 AromaticContact CZ2-CH2 3.87Å; W198-W207 HydrophobicContact CZ2-CH2 3.87Å; W198-W207 AromaticContact CZ2-CZ3 3.92Å; W198-W207 HydrophobicContact CZ2-CZ3 3.92Å
199	A	92.3	Very high	89.9	Confident	1 Å²	1	74.8 Å²	74.8	1%	0.008	42%	0.416	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-71.1	131.2	174.9	0	0	0	0	0	111	I184 F185 W201	I184-A199 HydrophobicContact CG2-CB 3.78Å; F185-A199 HydrophobicContact CD1-CB 4.31Å; F185-A199 HydrophobicContact CE1-CB 4.06Å; F185-A199 HydrophobicContact CE2-CB 4.49Å; F185-A199 HydrophobicContact CZ-CB 4.15Å; A199-W201 VanDerWaalsContact C-N 3.33Å; A199-W201 VanDerWaalsContact CB-CD1 3.43Å; A199-W201 HydrophobicContact CB-CD2 4.48Å; A199-W201 HydrophobicContact CB-CG 4.21Å; A199-W201 PolarHBondContact O-N 2.86Å
200	L	92.2	Very high	90.1	Very high	81 Å²	81	71.5 Å²	71.5	42%	0.424	39%	0.393	S	S	.	.			trans	-93	67	174.7	-67.8	91.2	0	0	0	109.3	I184	I184-L200 PolarHBondContact O-N 3.39Å
201	W	89.4	Confident	90.5	Very high	47 Å²	47	69 Å²	69	18%	0.178	38%	0.379	C	S	.	.			trans	-76.8	139.8	174.5	-63.7	122.1	0	0	0	111	I184 A199 D203 Y206 W207 Y210	I184-W201 HydrophobicContact CB-CH2 4.31Å; I184-W201 HydrophobicContact CB-CZ2 4.47Å; I184-W201 HydrophobicContact CD1-CH2 3.4Å; I184-W201 HydrophobicContact CD1-CZ2 4.05Å; I184-W201 HydrophobicContact CD1-CZ3 4.07Å; I184-W201 HydrophobicContact CG1-CH2 3.68Å; I184-W201 HydrophobicContact CG1-CZ2 4.3Å; I184-W201 HydrophobicContact CG1-CZ3 3.91Å; I184-W201 HydrophobicContact CG2-CD2 4.14Å; I184-W201 HydrophobicContact CG2-CE3 4.31Å; I184-W201 HydrophobicContact CG2-CH2 3.63Å; I184-W201 HydrophobicContact CG2-CZ2 3.38Å; I184-W201 HydrophobicContact CG2-CZ3 4.08Å; A199-W201 VanDerWaalsContact C-N 3.33Å; A199-W201 VanDerWaalsContact CB-CD1 3.43Å; A199-W201 HydrophobicContact CB-CD2 4.48Å; A199-W201 HydrophobicContact CB-CG 4.21Å; A199-W201 PolarHBondContact O-N 2.86Å; W201-D203 VanDerWaalsContact C-N 3.31Å; W201-D203 WeakPolarHBondContact CB-O 3.47Å; W201-Y206 HydrophobicContact CE3-CG 4.06Å; W201-Y206 HydrophobicContact CZ3-CG 4.38Å; W201-W207 AromaticContact NE1-CE3 3.68Å; W201-Y210 HydrophobicContact CH2-CD2 4.11Å; W201-Y210 HydrophobicContact CH2-CG 4Å; W201-Y210 HydrophobicContact CZ2-CD1 4.02Å; W201-Y210 HydrophobicContact CZ2-CD2 4.2Å; W201-Y210 AromaticContact CZ2-CG 3.72Å; W201-Y210 HydrophobicContact CZ2-CG 3.72Å
202	P	87.8	Confident	91.1	Very high	103 Å²	103	64.2 Å²	64.2	67%	0.669	35%	0.345	S	S	*	.	S	Bend	trans	-61.6	-43.2	169	-21.7	33.1	0	0	0	111.6
203	D	88.5	Confident	91.6	Very high	95 Å²	95	64.5 Å²	64.5	51%	0.508	35%	0.345	S	S	.	.	S	Bend	trans	-135.4	149.4	179.4	-59.9	-54.3	0	0	0	110	W201 S205 Y206	W201-D203 VanDerWaalsContact C-N 3.31Å; W201-D203 WeakPolarHBondContact CB-O 3.47Å; D203-S205 PolarHBondContact O-N 3.46Å; D203-S205 VanDerWaalsContact O-N 3.11Å; D203-Y206 HydrophobicContact CB-CD2 4.05Å; D203-Y206 HydrophobicContact CB-CE2 4.06Å; D203-Y206 WeakPolarHBondContact O-CD2 3.31Å; D203-Y206 PolarHBondContact O-N 2.89Å
204	D	85.8	Confident	92.1	Very high	138 Å²	138	62.5 Å²	62.5	74%	0.738	32%	0.321	S	S	*	.	G	3₁₀ helix	trans	-65.8	-16.2	179.1	-65.4	-31.2	0	0	0	112.8	Y206 W207	D204-Y206 PolarHBondContact O-N 3.39Å; D204-Y206 VanDerWaalsContact O-N 3.13Å; D204-W207 WeakPolarHBondContact O-CB 3.23Å; D204-W207 PolarHBondContact O-N 3.3Å; D204-W207 VanDerWaalsContact O-N 3.12Å
205	S	90.3	Very high	92.5	Very high	82 Å²	82	58.4 Å²	58.4	57%	0.573	30%	0.302	S	S	*	.	G	3₁₀ helix	trans	-61.8	-19.5	176.9	61	0	0	0	0	114.3	D203 P209	D203-S205 PolarHBondContact O-N 3.46Å; D203-S205 VanDerWaalsContact O-N 3.11Å; S205-P209 WeakPolarHBondContact O-CD 3.38Å; S205-P209 WeakPolarHBondContact O-CG 3.25Å
206	Y	92.4	Very high	92.9	Very high	113 Å²	113	61.5 Å²	61.5	44%	0.443	31%	0.313	S	S	.	.	G	3₁₀ helix	trans	-80.5	-17.6	178.4	-68.6	-89.3	0	0	0	113.2	W201 D203 D204 P209 Y210	W201-Y206 HydrophobicContact CE3-CG 4.06Å; W201-Y206 HydrophobicContact CZ3-CG 4.38Å; D203-Y206 HydrophobicContact CB-CD2 4.05Å; D203-Y206 HydrophobicContact CB-CE2 4.06Å; D203-Y206 WeakPolarHBondContact O-CD2 3.31Å; D203-Y206 PolarHBondContact O-N 2.89Å; D204-Y206 PolarHBondContact O-N 3.39Å; D204-Y206 VanDerWaalsContact O-N 3.13Å; Y206-P209 WeakPolarHBondContact O-CD 3.46Å; Y206-P209 WeakPolarHBondContact O-CG 3.29Å; Y206-Y210 WeakPolarHBondContact O-CB 3.45Å; Y206-Y210 PolarHBondContact O-N 2.95Å
207	W	91.9	Very high	93.2	Very high	64 Å²	64	61.7 Å²	61.7	24%	0.242	32%	0.315	C	S	.	.	H	α-helix	trans	-64.2	-56.1	-178.5	175.6	-94.6	0	0	0	112.1	W198 W201 D204 Y210 M211 N298	W198-W207 HydrophobicContact CH2-CH2 4.19Å; W198-W207 AromaticContact CZ2-CH2 3.87Å; W198-W207 HydrophobicContact CZ2-CH2 3.87Å; W198-W207 AromaticContact CZ2-CZ3 3.92Å; W198-W207 HydrophobicContact CZ2-CZ3 3.92Å; W201-W207 AromaticContact NE1-CE3 3.68Å; D204-W207 WeakPolarHBondContact O-CB 3.23Å; D204-W207 PolarHBondContact O-N 3.3Å; D204-W207 VanDerWaalsContact O-N 3.12Å; W207-Y210 PolarHBondContact O-N 3.22Å; W207-M211 HydrophobicContact CD2-CG 4.01Å; W207-M211 HydrophobicContact CG-CG 4.44Å; W207-M211 HydrophobicContact CH2-CE 4.4Å; W207-M211 HydrophobicContact CH2-CG 4.33Å; W207-M211 HydrophobicContact CH2-SD 4.07Å; W207-M211 HydrophobicContact CZ2-CE 4Å; W207-M211 HydrophobicContact CZ2-CG 3.76Å; W207-M211 HydrophobicContact CZ2-SD 3.97Å; W207-M211 WeakPolarHBondContact O-CG 3.32Å; W207-M211 PolarHBondContact O-N 3.03Å; W207-N298 PolarHBondContact NE1-OD1 3.38Å
208	T	94.2	Very high	93.3	Very high	38 Å²	38	61.5 Å²	61.5	23%	0.233	31%	0.313	C	S	.	.	H	α-helix	trans	-55.4	-51.1	-178.4	-54.6	0	0	0	0	113.5	Y210 T212 N298 F299	T208-Y210 PolarHBondContact O-N 3.49Å; T208-T212 VanDerWaalsContact O-CB 3.28Å; T208-T212 WeakPolarHBondContact O-CB 3.47Å; T208-T212 PolarHBondContact O-N 3.49Å; T208-T212 PolarHBondContact O-OG1 3.48Å; T208-N298 HydrophobicContact CG2-CB 4.41Å; T208-N298 WeakPolarHBondContact CG2-O 3.47Å; T208-N298 PolarHBondContact OG1-O 2.96Å; T208-F299 HydrophobicContact CG2-CD1 4.16Å; T208-F299 HydrophobicContact CG2-CE1 3.82Å; T208-F299 HydrophobicContact CG2-CE2 4.49Å; T208-F299 HydrophobicContact CG2-CZ 3.99Å
209	P	94.8	Very high	93.6	Very high	65 Å²	65	56.2 Å²	56.2	42%	0.422	29%	0.294	S	S	.	.	H	α-helix	trans	-65.1	-37.6	178.8	24.2	-33.1	0	0	0	112.6	S205 Y206 T212 I213	S205-P209 WeakPolarHBondContact O-CD 3.38Å; S205-P209 WeakPolarHBondContact O-CG 3.25Å; Y206-P209 WeakPolarHBondContact O-CD 3.46Å; Y206-P209 WeakPolarHBondContact O-CG 3.29Å; P209-T212 PolarHBondContact O-N 3.33Å; P209-I213 WeakPolarHBondContact O-CD1 3.48Å; P209-I213 VanDerWaalsContact O-CG1 3.26Å; P209-I213 WeakPolarHBondContact O-CG1 3.35Å; P209-I213 PolarHBondContact O-N 2.88Å
210	Y	94.9	Very high	93.9	Very high	33 Å²	33	58.7 Å²	58.7	13%	0.129	30%	0.304	C	S	.	.	H	α-helix	trans	-62.2	-52.3	176.5	171.9	-97.8	0	0	0	111.7	T181 I184 F185 W201 Y206 W207 T208 T212 I213 V214	T181-Y210 PolarHBondContact OG1-OH 3.21Å; I184-Y210 HydrophobicContact CD1-CD2 3.89Å; I184-Y210 HydrophobicContact CD1-CE2 3.72Å; F185-Y210 HydrophobicContact CE2-CE1 4.28Å; W201-Y210 HydrophobicContact CH2-CD2 4.11Å; W201-Y210 HydrophobicContact CH2-CG 4Å; W201-Y210 HydrophobicContact CZ2-CD1 4.02Å; W201-Y210 HydrophobicContact CZ2-CD2 4.2Å; W201-Y210 AromaticContact CZ2-CG 3.72Å; W201-Y210 HydrophobicContact CZ2-CG 3.72Å; Y206-Y210 WeakPolarHBondContact O-CB 3.45Å; Y206-Y210 PolarHBondContact O-N 2.95Å; W207-Y210 PolarHBondContact O-N 3.22Å; T208-Y210 PolarHBondContact O-N 3.49Å; Y210-T212 VanDerWaalsContact C-N 3.29Å; Y210-T212 PolarHBondContact O-N 3.4Å; Y210-I213 PolarHBondContact O-N 2.98Å; Y210-V214 HydrophobicContact CD1-CG2 4.45Å; Y210-V214 HydrophobicContact CE1-CG2 4.01Å; Y210-V214 HydrophobicContact CE2-CG2 4.15Å; Y210-V214 WeakPolarHBondContact O-CG2 3.14Å; Y210-V214 PolarHBondContact O-N 3.17Å
211	M	94.5	Very high	94.2	Very high	23 Å²	23	58.7 Å²	58.7	11%	0.113	30%	0.304	C	S	.	.	H	α-helix	trans	-63.6	-37.3	179.7	-67	-60.3	-76.3	0	0	111.6	W207 I213 V214 A215 D294 N298	W207-M211 HydrophobicContact CD2-CG 4.01Å; W207-M211 HydrophobicContact CG-CG 4.44Å; W207-M211 HydrophobicContact CH2-CE 4.4Å; W207-M211 HydrophobicContact CH2-CG 4.33Å; W207-M211 HydrophobicContact CH2-SD 4.07Å; W207-M211 HydrophobicContact CZ2-CE 4Å; W207-M211 HydrophobicContact CZ2-CG 3.76Å; W207-M211 HydrophobicContact CZ2-SD 3.97Å; W207-M211 WeakPolarHBondContact O-CG 3.32Å; W207-M211 PolarHBondContact O-N 3.03Å; M211-I213 PolarHBondContact O-N 2.88Å; M211-V214 PolarHBondContact O-N 3.46Å; M211-A215 WeakPolarHBondContact O-CB 3.31Å; M211-A215 PolarHBondContact O-N 3.23Å; M211-D294 VanDerWaalsContact CE-OD1 3.31Å; M211-D294 WeakPolarHBondContact CE-OD1 3.14Å; M211-N298 VanDerWaalsContact CB-ND2 3.32Å; M211-N298 WeakPolarHBondContact CB-ND2 3.35Å
212	T	96.5	Very high	94.6	Very high	26 Å²	26	56.6 Å²	56.6	16%	0.16	30%	0.296	C	S	.	.	H	α-helix	trans	-59	-49.6	173.3	-59.5	0	0	0	0	111.1	T208 P209 Y210 V214 A215 F216 I295	T208-T212 VanDerWaalsContact O-CB 3.28Å; T208-T212 WeakPolarHBondContact O-CB 3.47Å; T208-T212 PolarHBondContact O-N 3.49Å; T208-T212 PolarHBondContact O-OG1 3.48Å; P209-T212 PolarHBondContact O-N 3.33Å; Y210-T212 VanDerWaalsContact C-N 3.29Å; Y210-T212 PolarHBondContact O-N 3.4Å; T212-V214 VanDerWaalsContact C-N 3.33Å; T212-V214 PolarHBondContact O-N 3Å; T212-A215 WeakPolarHBondContact O-CB 3.44Å; T212-A215 PolarHBondContact O-N 3.29Å; T212-F216 HydrophobicContact CG2-CD2 3.89Å; T212-F216 HydrophobicContact CG2-CE2 3.77Å; T212-F216 VanDerWaalsContact O-CD2 3.26Å; T212-F216 WeakPolarHBondContact O-CD2 3.28Å; T212-F216 PolarHBondContact O-N 2.93Å; T212-I295 HydrophobicContact CG2-CD1 4.47Å
213	I	97.1	Very high	95.1	Very high	100 Å²	100	53.1 Å²	53.1	51%	0.513	27%	0.272	S	S	.	.	H	α-helix	trans	-59	-45.3	177.8	-70.5	164.7	0	0	0	110.9	P209 Y210 M211 A215 F216 L217	P209-I213 WeakPolarHBondContact O-CD1 3.48Å; P209-I213 VanDerWaalsContact O-CG1 3.26Å; P209-I213 WeakPolarHBondContact O-CG1 3.35Å; P209-I213 PolarHBondContact O-N 2.88Å; Y210-I213 PolarHBondContact O-N 2.98Å; M211-I213 PolarHBondContact O-N 2.88Å; I213-A215 VanDerWaalsContact C-N 3.34Å; I213-A215 PolarHBondContact O-N 2.98Å; I213-F216 PolarHBondContact O-N 3.49Å; I213-L217 HydrophobicContact CG2-CD1 3.71Å; I213-L217 HydrophobicContact CG2-CG 4.21Å; I213-L217 WeakPolarHBondContact O-CG 3.16Å; I213-L217 PolarHBondContact O-N 2.97Å
214	V	96.3	Very high	95.5	Very high	16 Å²	16	52.2 Å²	52.2	10%	0.097	27%	0.27	C	S	.	.	H	α-helix	trans	-59.1	-45.7	177	173.3	0	0	0	0	110.8	Y210 M211 T212 F216 L217 V218	Y210-V214 HydrophobicContact CD1-CG2 4.45Å; Y210-V214 HydrophobicContact CE1-CG2 4.01Å; Y210-V214 HydrophobicContact CE2-CG2 4.15Å; Y210-V214 WeakPolarHBondContact O-CG2 3.14Å; Y210-V214 PolarHBondContact O-N 3.17Å; M211-V214 PolarHBondContact O-N 3.46Å; T212-V214 VanDerWaalsContact C-N 3.33Å; T212-V214 PolarHBondContact O-N 3Å; V214-F216 VanDerWaalsContact C-N 3.32Å; V214-F216 PolarHBondContact O-N 2.94Å; V214-L217 PolarHBondContact O-N 3.3Å; V214-V218 HydrophobicContact CG1-CG2 3.94Å; V214-V218 VanDerWaalsContact O-CB 3.31Å; V214-V218 WeakPolarHBondContact O-CB 2.94Å; V214-V218 WeakPolarHBondContact O-CG2 3.11Å; V214-V218 PolarHBondContact O-N 3.39Å
215	A	97.2	Very high	96.1	Very high	0 Å²	0	48.8 Å²	48.8	0%	0	25%	0.251	C	S	.	.	H	α-helix	trans	-59.6	-40.1	177.5	0	0	0	0	0	112.5	M211 T212 I213 Y219 F220 F291 I295	M211-A215 WeakPolarHBondContact O-CB 3.31Å; M211-A215 PolarHBondContact O-N 3.23Å; T212-A215 WeakPolarHBondContact O-CB 3.44Å; T212-A215 PolarHBondContact O-N 3.29Å; I213-A215 VanDerWaalsContact C-N 3.34Å; I213-A215 PolarHBondContact O-N 2.98Å; A215-Y219 WeakPolarHBondContact O-CA 3.35Å; A215-Y219 WeakPolarHBondContact O-CB 3.18Å; A215-Y219 PolarHBondContact O-N 3.01Å; A215-F220 HydrophobicContact CB-CD2 4.38Å; A215-F220 HydrophobicContact CB-CE2 4.14Å; A215-F220 WeakPolarHBondContact O-CD2 3.4Å; A215-F220 PolarHBondContact O-N 2.98Å; A215-F220 VanDerWaalsContact O-N 3.14Å; A215-F291 HydrophobicContact CB-CD1 3.65Å; A215-F291 HydrophobicContact CB-CE1 4.07Å; A215-I295 HydrophobicContact CB-CD1 3.87Å; A215-I295 HydrophobicContact CB-CG1 4.14Å
216	F	98	Very high	96.4	Very high	100 Å²	100	44.9 Å²	44.9	44%	0.439	22%	0.224	S	C	.	.	I	π-helix	trans	-67.2	-46.1	175.2	-84.5	-82.9	0	0	0	112.7	T212 I213 V214 F220 I221	T212-F216 HydrophobicContact CG2-CD2 3.89Å; T212-F216 HydrophobicContact CG2-CE2 3.77Å; T212-F216 VanDerWaalsContact O-CD2 3.26Å; T212-F216 WeakPolarHBondContact O-CD2 3.28Å; T212-F216 PolarHBondContact O-N 2.93Å; I213-F216 PolarHBondContact O-N 3.49Å; V214-F216 VanDerWaalsContact C-N 3.32Å; V214-F216 PolarHBondContact O-N 2.94Å; F216-F220 HydrophobicContact CD1-CB 3.8Å; F216-F220 HydrophobicContact CD1-CD2 4.18Å; F216-F220 HydrophobicContact CD1-CG 4.3Å; F216-F220 HydrophobicContact CE1-CB 4.18Å; F216-F220 HydrophobicContact CE1-CD2 4.34Å; F216-F220 HydrophobicContact CE1-CG 4.38Å; F216-F220 HydrophobicContact CG-CB 4.48Å; F216-F220 HydrophobicContact CG-CD2 4.26Å; F216-F220 PolarHBondContact O-N 3.41Å; F216-I221 HydrophobicContact CB-CD1 4.35Å; F216-I221 VanDerWaalsContact O-CB 3.3Å; F216-I221 WeakPolarHBondContact O-CB 3.45Å; F216-I221 WeakPolarHBondContact O-CG1 3.35Å; F216-I221 PolarHBondContact O-N 2.82Å
217	L	97.9	Very high	96.6	Very high	44 Å²	44	42.3 Å²	42.3	23%	0.23	22%	0.222	C	C	.	.	I	π-helix	trans	-73.4	-31.7	-175.1	-66.8	177.3	0	0	0	113.6	Y133 Y137 I213 V214 I221 P222	Y133-L217 HydrophobicContact CE1-CB 3.67Å; Y137-L217 WeakPolarHBondContact CE1-O 3.48Å; Y137-L217 PolarHBondContact OH-O 2.99Å; Y137-L217 VanDerWaalsContact OH-O 3.08Å; I213-L217 HydrophobicContact CG2-CD1 3.71Å; I213-L217 HydrophobicContact CG2-CG 4.21Å; I213-L217 WeakPolarHBondContact O-CG 3.16Å; I213-L217 PolarHBondContact O-N 2.97Å; V214-L217 PolarHBondContact O-N 3.3Å; L217-I221 HydrophobicContact CD2-CD1 4.23Å; L217-P222 WeakPolarHBondContact O-CD 3.35Å; L217-P222 VanDerWaalsContact O-CG 3.27Å; L217-P222 WeakPolarHBondContact O-CG 3.43Å
218	V	97.1	Very high	96.8	Very high	0 Å²	0	43.8 Å²	43.8	0%	0	23%	0.234	C	C	.	.	I	π-helix	trans	-91.9	-30.2	-179.5	179.8	0	0	0	0	111.9	L132 Y133 T136 V214 P222 F291	L132-V218 HydrophobicContact CD1-CG1 3.56Å; L132-V218 HydrophobicContact CD2-CG1 4.18Å; L132-V218 HydrophobicContact CD2-CG2 4.06Å; L132-V218 HydrophobicContact CG-CG1 3.71Å; L132-V218 HydrophobicContact CG-CG2 4.05Å; Y133-V218 HydrophobicContact CD1-CG2 3.63Å; Y133-V218 HydrophobicContact CE1-CB 4.41Å; Y133-V218 HydrophobicContact CE1-CG2 3.22Å; Y133-V218 HydrophobicContact CE2-CG2 4.21Å; Y133-V218 HydrophobicContact CG-CG2 4.26Å; T136-V218 WeakPolarHBondContact CG2-O 3.43Å; V214-V218 HydrophobicContact CG1-CG2 3.94Å; V214-V218 VanDerWaalsContact O-CB 3.31Å; V214-V218 WeakPolarHBondContact O-CB 2.94Å; V214-V218 WeakPolarHBondContact O-CG2 3.11Å; V214-V218 PolarHBondContact O-N 3.39Å; V218-P222 WeakPolarHBondContact O-CG 3.21Å; V218-F291 HydrophobicContact CB-CE1 4.5Å; V218-F291 HydrophobicContact CB-CE2 4.37Å; V218-F291 HydrophobicContact CB-CZ 3.75Å; V218-F291 HydrophobicContact CG1-CE2 3.89Å; V218-F291 HydrophobicContact CG1-CZ 3.54Å
219	Y	97.6	Very high	96.9	Very high	11 Å²	11	43.7 Å²	43.7	4%	0.043	23%	0.231	C	C	.	.	I	π-helix	trans	-125.6	-64	-171.6	176.8	-108.2	0	0	0	114.6	A215 I221 P222 L223 F283 W287 S288 F291	A215-Y219 WeakPolarHBondContact O-CA 3.35Å; A215-Y219 WeakPolarHBondContact O-CB 3.18Å; A215-Y219 PolarHBondContact O-N 3.01Å; Y219-I221 PolarHBondContact O-N 3.24Å; Y219-P222 WeakPolarHBondContact O-CD 3.12Å; Y219-L223 HydrophobicContact CE1-CD2 4.23Å; Y219-L223 HydrophobicContact CE2-CD2 3.99Å; Y219-L223 WeakPolarHBondContact O-CB 2.93Å; Y219-L223 PolarHBondContact O-N 3.34Å; Y219-L223 WeakPolarHBondContact OH-CD2 3.48Å; Y219-F283 HydrophobicContact CD2-CE1 4.08Å; Y219-F283 HydrophobicContact CD2-CZ 4.05Å; Y219-F283 HydrophobicContact CE2-CE1 4.35Å; Y219-W287 HydrophobicContact CD2-CB 3.85Å; Y219-W287 HydrophobicContact CE2-CB 4.05Å; Y219-S288 WeakPolarHBondContact OH-CA 3.45Å; Y219-S288 VanDerWaalsContact OH-CB 3.26Å; Y219-S288 WeakPolarHBondContact OH-CB 3.47Å; Y219-S288 PolarHBondContact OH-OG 3.03Å; Y219-F291 VanDerWaalsContact CB-CE2 3.4Å; Y219-F291 HydrophobicContact CD1-CB 3.7Å; Y219-F291 AromaticContact CD1-CD2 4Å; Y219-F291 HydrophobicContact CD1-CD2 4Å; Y219-F291 HydrophobicContact CD1-CG 4.04Å; Y219-F291 AromaticContact CD2-CD2 3.87Å; Y219-F291 HydrophobicContact CD2-CD2 3.87Å; Y219-F291 HydrophobicContact CD2-CE2 4.44Å; Y219-F291 HydrophobicContact CE1-CB 4.24Å; Y219-F291 HydrophobicContact CG-CB 4.06Å; Y219-F291 AromaticContact CG-CD2 3.42Å; Y219-F291 HydrophobicContact CG-CD2 3.42Å; Y219-F291 VanDerWaalsContact CG-CD2 3.42Å; Y219-F291 HydrophobicContact CG-CE2 4.07Å; Y219-F291 AromaticContact CG-CG 3.91Å; Y219-F291 HydrophobicContact CG-CG 3.91Å
220	F	97.9	Very high	96.9	Very high	54 Å²	54	41.2 Å²	41.2	24%	0.237	21%	0.214	C	C	.	.	I	π-helix	trans	-64.7	-44.4	-169.9	-65.9	-74.8	0	0	0	113.5	A215 F216 T224 L292 I295	A215-F220 HydrophobicContact CB-CD2 4.38Å; A215-F220 HydrophobicContact CB-CE2 4.14Å; A215-F220 WeakPolarHBondContact O-CD2 3.4Å; A215-F220 PolarHBondContact O-N 2.98Å; A215-F220 VanDerWaalsContact O-N 3.14Å; F216-F220 HydrophobicContact CD1-CB 3.8Å; F216-F220 HydrophobicContact CD1-CD2 4.18Å; F216-F220 HydrophobicContact CD1-CG 4.3Å; F216-F220 HydrophobicContact CE1-CB 4.18Å; F216-F220 HydrophobicContact CE1-CD2 4.34Å; F216-F220 HydrophobicContact CE1-CG 4.38Å; F216-F220 HydrophobicContact CG-CB 4.48Å; F216-F220 HydrophobicContact CG-CD2 4.26Å; F216-F220 PolarHBondContact O-N 3.41Å; F220-T224 WeakPolarHBondContact O-CB 3.22Å; F220-T224 PolarHBondContact O-N 3.46Å; F220-T224 PolarHBondContact O-OG1 3.37Å; F220-L292 HydrophobicContact CZ-CD2 4.48Å; F220-I295 HydrophobicContact CE2-CG1 4.31Å
221	I	98	Very high	96.9	Very high	81 Å²	81	41.7 Å²	41.7	42%	0.415	23%	0.229	S	C	.	.	H	α-helix	trans	-67	-52.5	177.5	-67.2	166.7	0	0	0	110.4	F216 L217 Y219 L223 T224 I225	F216-I221 HydrophobicContact CB-CD1 4.35Å; F216-I221 VanDerWaalsContact O-CB 3.3Å; F216-I221 WeakPolarHBondContact O-CB 3.45Å; F216-I221 WeakPolarHBondContact O-CG1 3.35Å; F216-I221 PolarHBondContact O-N 2.82Å; L217-I221 HydrophobicContact CD2-CD1 4.23Å; Y219-I221 PolarHBondContact O-N 3.24Å; I221-L223 PolarHBondContact O-N 2.8Å; I221-T224 PolarHBondContact O-N 3.06Å; I221-I225 HydrophobicContact CG2-CD1 3.78Å; I221-I225 HydrophobicContact CG2-CG1 4.48Å; I221-I225 WeakPolarHBondContact O-CG1 3.44Å; I221-I225 PolarHBondContact O-N 3.46Å
222	P	98.1	Very high	96.9	Very high	2 Å²	2	43.4 Å²	43.4	1%	0.013	24%	0.238	C	C	.	.	H	α-helix	trans	-54.7	-46	174.7	-31.7	39.9	0	0	0	113.9	T136 Y137 V140 L217 V218 Y219 T224 I225 I226	T136-P222 HydrophobicContact CG2-CB 3.49Å; T136-P222 VanDerWaalsContact CG2-CB 3.49Å; T136-P222 HydrophobicContact CG2-CG 3.5Å; T136-P222 VanDerWaalsContact CG2-CG 3.5Å; Y137-P222 HydrophobicContact CD1-CG 4.5Å; Y137-P222 HydrophobicContact CE1-CG 4.03Å; V140-P222 HydrophobicContact CG2-CB 3.8Å; L217-P222 WeakPolarHBondContact O-CD 3.35Å; L217-P222 VanDerWaalsContact O-CG 3.27Å; L217-P222 WeakPolarHBondContact O-CG 3.43Å; V218-P222 WeakPolarHBondContact O-CG 3.21Å; Y219-P222 WeakPolarHBondContact O-CD 3.12Å; P222-T224 VanDerWaalsContact C-N 3.33Å; P222-T224 PolarHBondContact O-N 2.9Å; P222-I225 PolarHBondContact O-N 3.1Å; P222-I226 WeakPolarHBondContact O-CB 3.25Å; P222-I226 WeakPolarHBondContact O-CG1 3.41Å; P222-I226 PolarHBondContact O-N 2.99Å
223	L	97.6	Very high	96.7	Very high	30 Å²	30	42.2 Å²	42.2	16%	0.157	23%	0.23	C	C	.	.	H	α-helix	trans	-59.2	-44.6	178.1	177.6	60.9	0	0	0	111.6	Y219 I221 I226 S227 I284	Y219-L223 HydrophobicContact CE1-CD2 4.23Å; Y219-L223 HydrophobicContact CE2-CD2 3.99Å; Y219-L223 WeakPolarHBondContact O-CB 2.93Å; Y219-L223 PolarHBondContact O-N 3.34Å; Y219-L223 WeakPolarHBondContact OH-CD2 3.48Å; I221-L223 PolarHBondContact O-N 2.8Å; L223-I226 PolarHBondContact O-N 3.25Å; L223-S227 VanDerWaalsContact O-CB 3.23Å; L223-S227 WeakPolarHBondContact O-CB 3.28Å; L223-S227 PolarHBondContact O-N 2.87Å; L223-S227 PolarHBondContact O-OG 3.5Å; L223-I284 HydrophobicContact CD1-CD1 3.74Å; L223-I284 HydrophobicContact CD1-CG1 3.56Å
224	T	97.8	Very high	96.6	Very high	77 Å²	77	40.8 Å²	40.8	47%	0.472	22%	0.223	S	C	.	.	H	α-helix	trans	-61.8	-48.1	177.9	-59.8	0	0	0	0	110.8	F220 I221 P222 S227 I228	F220-T224 WeakPolarHBondContact O-CB 3.22Å; F220-T224 PolarHBondContact O-N 3.46Å; F220-T224 PolarHBondContact O-OG1 3.37Å; I221-T224 PolarHBondContact O-N 3.06Å; P222-T224 VanDerWaalsContact C-N 3.33Å; P222-T224 PolarHBondContact O-N 2.9Å; T224-S227 PolarHBondContact O-N 3.44Å; T224-I228 HydrophobicContact CG2-CD1 3.84Å; T224-I228 VanDerWaalsContact O-CG1 3.28Å; T224-I228 WeakPolarHBondContact O-CG1 3.34Å; T224-I228 PolarHBondContact O-N 2.82Å
225	I	97.9	Very high	96.5	Very high	65 Å²	65	48.4 Å²	48.4	33%	0.333	25%	0.25	S	C	.	.	H	α-helix	trans	-60.2	-50.3	178.1	-65.9	167.4	0	0	0	110.4	V140 I221 P222 S227 I228 M229	V140-I225 HydrophobicContact CG1-CG2 3.89Å; I221-I225 HydrophobicContact CG2-CD1 3.78Å; I221-I225 HydrophobicContact CG2-CG1 4.48Å; I221-I225 WeakPolarHBondContact O-CG1 3.44Å; I221-I225 PolarHBondContact O-N 3.46Å; P222-I225 PolarHBondContact O-N 3.1Å; I225-S227 VanDerWaalsContact C-N 3.34Å; I225-S227 PolarHBondContact O-N 3.31Å; I225-I228 PolarHBondContact O-N 2.75Å; I225-M229 HydrophobicContact CG2-CG 4.31Å; I225-M229 WeakPolarHBondContact O-CB 3.49Å; I225-M229 WeakPolarHBondContact O-CG 3.34Å; I225-M229 PolarHBondContact O-N 2.89Å
226	I	97.1	Very high	96.3	Very high	1 Å²	1	49.7 Å²	49.7	1%	0.005	26%	0.257	C	S	.	.	H	α-helix	trans	-58.7	-47.3	179.6	-69.2	170.1	0	0	0	110.2	L139 V140 P222 L223 I228 M229 Y230 I280	L139-I226 HydrophobicContact CB-CD1 4.2Å; V140-I226 HydrophobicContact CG2-CD1 4.06Å; V140-I226 HydrophobicContact CG2-CG1 4.07Å; P222-I226 WeakPolarHBondContact O-CB 3.25Å; P222-I226 WeakPolarHBondContact O-CG1 3.41Å; P222-I226 PolarHBondContact O-N 2.99Å; L223-I226 PolarHBondContact O-N 3.25Å; I226-I228 PolarHBondContact O-N 3.47Å; I226-M229 PolarHBondContact O-N 3.34Å; I226-Y230 HydrophobicContact CG2-CD2 4.06Å; I226-Y230 HydrophobicContact CG2-CE2 4.44Å; I226-Y230 WeakPolarHBondContact O-CD2 3.24Å; I226-Y230 PolarHBondContact O-N 2.96Å; I226-I280 HydrophobicContact CG2-CB 4.28Å; I226-I280 HydrophobicContact CG2-CD1 3.57Å; I226-I280 HydrophobicContact CG2-CG1 3.78Å; I226-I280 HydrophobicContact CG2-CG2 3.52Å
227	S	96.2	Very high	95.9	Very high	59 Å²	59	46.8 Å²	46.8	41%	0.413	25%	0.246	S	C	.	.	H	α-helix	trans	-63	-44.6	-177.7	-59.8	0	0	0	0	112.1	L223 T224 I225 Y230 G231	L223-S227 VanDerWaalsContact O-CB 3.23Å; L223-S227 WeakPolarHBondContact O-CB 3.28Å; L223-S227 PolarHBondContact O-N 2.87Å; L223-S227 PolarHBondContact O-OG 3.5Å; T224-S227 PolarHBondContact O-N 3.44Å; I225-S227 VanDerWaalsContact C-N 3.34Å; I225-S227 PolarHBondContact O-N 3.31Å; S227-Y230 PolarHBondContact O-N 3.46Å; S227-G231 PolarHBondContact O-N 2.86Å
228	I	96.9	Very high	95.5	Very high	94 Å²	94	53.4 Å²	53.4	48%	0.482	27%	0.268	S	S	.	.	H	α-helix	trans	-62.7	-48	176.2	-66.1	168.4	0	0	0	110.3	T224 I225 I226 Y230 G231 I232	T224-I228 HydrophobicContact CG2-CD1 3.84Å; T224-I228 VanDerWaalsContact O-CG1 3.28Å; T224-I228 WeakPolarHBondContact O-CG1 3.34Å; T224-I228 PolarHBondContact O-N 2.82Å; I225-I228 PolarHBondContact O-N 2.75Å; I226-I228 PolarHBondContact O-N 3.47Å; I228-Y230 VanDerWaalsContact C-N 3.34Å; I228-Y230 PolarHBondContact O-N 2.89Å; I228-G231 PolarHBondContact O-N 3.33Å; I228-I232 HydrophobicContact CG2-CD1 4.02Å; I228-I232 WeakPolarHBondContact O-CG1 3.34Å; I228-I232 PolarHBondContact O-N 3.35Å
229	M	95.6	Very high	95.2	Very high	37 Å²	37	57.8 Å²	57.8	18%	0.182	29%	0.291	C	S	.	.	H	α-helix	trans	-59.5	-44.4	-180	-70.9	-60.2	104.1	0	0	111.6	Y147 I225 I226 I232 V233	Y147-M229 HydrophobicContact CD1-SD 4.15Å; Y147-M229 HydrophobicContact CD2-SD 3.99Å; Y147-M229 HydrophobicContact CG-SD 3.77Å; I225-M229 HydrophobicContact CG2-CG 4.31Å; I225-M229 WeakPolarHBondContact O-CB 3.49Å; I225-M229 WeakPolarHBondContact O-CG 3.34Å; I225-M229 PolarHBondContact O-N 2.89Å; I226-M229 PolarHBondContact O-N 3.34Å; M229-I232 HydrophobicContact CE-CD1 4.2Å; M229-I232 PolarHBondContact O-N 3.1Å; M229-V233 VanDerWaalsContact O-CG2 3.29Å; M229-V233 WeakPolarHBondContact O-CG2 3.34Å; M229-V233 PolarHBondContact O-N 3.08Å
230	Y	94.1	Very high	94.7	Very high	13 Å²	13	61.6 Å²	61.6	5%	0.051	31%	0.308	C	S	.	.	H	α-helix	trans	-73.3	-34.8	178.4	-87.6	-93.9	0	0	0	113.6	S143 R146 I226 S227 I228 I232 V233 I234 S276 I277 I280	S143-Y230 WeakPolarHBondContact OG-CE2 3.36Å; R146-Y230 WeakPolarHBondContact CG-OH 3.47Å; I226-Y230 HydrophobicContact CG2-CD2 4.06Å; I226-Y230 HydrophobicContact CG2-CE2 4.44Å; I226-Y230 WeakPolarHBondContact O-CD2 3.24Å; I226-Y230 PolarHBondContact O-N 2.96Å; S227-Y230 PolarHBondContact O-N 3.46Å; I228-Y230 VanDerWaalsContact C-N 3.34Å; I228-Y230 PolarHBondContact O-N 2.89Å; Y230-I232 VanDerWaalsContact C-N 3.26Å; Y230-I232 PolarHBondContact O-N 3.39Å; Y230-V233 PolarHBondContact O-N 3.38Å; Y230-I234 WeakPolarHBondContact O-CB 3.4Å; Y230-I234 VanDerWaalsContact O-CG1 3.22Å; Y230-I234 WeakPolarHBondContact O-CG1 3.48Å; Y230-I234 PolarHBondContact O-N 3.48Å; Y230-S276 WeakPolarHBondContact OH-CB 3.16Å; Y230-S276 PolarHBondContact OH-OG 3.37Å; Y230-I277 HydrophobicContact CD1-CG1 3.82Å; Y230-I277 HydrophobicContact CE1-CG1 3.72Å; Y230-I280 HydrophobicContact CD1-CD1 4.36Å; Y230-I280 HydrophobicContact CD2-CD1 3.47Å; Y230-I280 VanDerWaalsContact CD2-CD1 3.47Å; Y230-I280 HydrophobicContact CE1-CD1 3.94Å; Y230-I280 HydrophobicContact CE2-CD1 2.96Å; Y230-I280 HydrophobicContact CE2-CG1 4.45Å; Y230-I280 HydrophobicContact CG-CD1 4.14Å; Y230-I280 WeakPolarHBondContact OH-CD1 3.21Å
231	G	95	Very high	94.1	Very high	43 Å²	43	61.9 Å²	61.9	44%	0.443	32%	0.316	S	S	.	.	H	α-helix	trans	-54.7	-45.8	170.5	0	0	0	0	0	111.2	S227 I228 R235	S227-G231 PolarHBondContact O-N 2.86Å; I228-G231 PolarHBondContact O-N 3.33Å; G231-R235 VanDerWaalsContact O-CB 3.25Å; G231-R235 WeakPolarHBondContact O-CB 3.44Å; G231-R235 PolarHBondContact O-N 2.86Å
232	I	95.5	Very high	93.6	Very high	59 Å²	59	64.9 Å²	64.9	30%	0.303	33%	0.326	S	S	.	.	H	α-helix	trans	-68.7	-43.2	176.9	-58.9	163.2	0	0	0	111.7	Y147 V151 I228 M229 Y230 I234 R235 T236	Y147-I232 HydrophobicContact CD2-CB 4.33Å; Y147-I232 HydrophobicContact CD2-CG2 4.11Å; Y147-I232 HydrophobicContact CE2-CB 4.25Å; Y147-I232 HydrophobicContact CE2-CD1 4.13Å; Y147-I232 HydrophobicContact CE2-CG2 3.71Å; V151-I232 HydrophobicContact CG2-CG2 4.37Å; I228-I232 HydrophobicContact CG2-CD1 4.02Å; I228-I232 WeakPolarHBondContact O-CG1 3.34Å; I228-I232 PolarHBondContact O-N 3.35Å; M229-I232 HydrophobicContact CE-CD1 4.2Å; M229-I232 PolarHBondContact O-N 3.1Å; Y230-I232 VanDerWaalsContact C-N 3.26Å; Y230-I232 PolarHBondContact O-N 3.39Å; I232-I234 PolarHBondContact O-N 3.44Å; I232-R235 PolarHBondContact O-N 2.68Å; I232-T236 VanDerWaalsContact O-CB 3.3Å; I232-T236 WeakPolarHBondContact O-CB 3.41Å; I232-T236 PolarHBondContact O-N 2.75Å; I232-T236 PolarHBondContact O-OG1 3.15Å
233	V	92.7	Very high	93	Very high	0 Å²	0	68.4 Å²	68.4	0%	0	35%	0.348	C	S	.	.	H	α-helix	trans	-58.6	-49.7	177.6	166.8	0	0	0	0	110.7	I150 M229 Y230 T236 I237	I150-V233 HydrophobicContact CG1-CG1 4.45Å; M229-V233 VanDerWaalsContact O-CG2 3.29Å; M229-V233 WeakPolarHBondContact O-CG2 3.34Å; M229-V233 PolarHBondContact O-N 3.08Å; Y230-V233 PolarHBondContact O-N 3.38Å; V233-T236 PolarHBondContact O-N 3.36Å; V233-I237 HydrophobicContact CG1-CD1 3.76Å; V233-I237 WeakPolarHBondContact O-CD1 3.36Å; V233-I237 VanDerWaalsContact O-CG1 3.23Å; V233-I237 WeakPolarHBondContact O-CG1 3.47Å; V233-I237 PolarHBondContact O-N 2.99Å
234	I	93.6	Very high	92.1	Very high	70 Å²	70	69.6 Å²	69.6	36%	0.359	35%	0.351	S	S	.	.	H	α-helix	trans	-61.1	-53.7	178.8	-67.9	168.8	0	0	0	109	Y230 I232 T236 I237 W238	Y230-I234 WeakPolarHBondContact O-CB 3.4Å; Y230-I234 VanDerWaalsContact O-CG1 3.22Å; Y230-I234 WeakPolarHBondContact O-CG1 3.48Å; Y230-I234 PolarHBondContact O-N 3.48Å; I232-I234 PolarHBondContact O-N 3.44Å; I234-T236 PolarHBondContact O-N 3.21Å; I234-I237 WeakPolarHBondContact O-CB 3.46Å; I234-I237 PolarHBondContact O-N 3.17Å; I234-W238 PolarHBondContact O-N 3.35Å
235	R	95.1	Very high	91.3	Very high	177 Å²	177	72.6 Å²	72.6	67%	0.668	36%	0.359	S	S	*	.	H	α-helix	trans	-52.5	-43.3	177.2	-178	-179.7	175.8	-172.7	-0.2	112.4	G231 I232 W238 I239	G231-R235 VanDerWaalsContact O-CB 3.25Å; G231-R235 WeakPolarHBondContact O-CB 3.44Å; G231-R235 PolarHBondContact O-N 2.86Å; I232-R235 PolarHBondContact O-N 2.68Å; R235-W238 PolarHBondContact O-N 3.33Å; R235-I239 HydrophobicContact CG-CD1 3.84Å; R235-I239 HydrophobicContact CG-CG1 4.49Å; R235-I239 VanDerWaalsContact O-CG1 3.29Å; R235-I239 WeakPolarHBondContact O-CG1 3.29Å; R235-I239 PolarHBondContact O-N 3.16Å
236	T	91.9	Very high	90.5	Very high	26 Å²	26	72.7 Å²	72.7	16%	0.16	36%	0.363	C	S	.	.	H	α-helix	trans	-65.3	-40.2	179.4	-56.8	0	0	0	0	112	I150 V151 I232 V233 I234 K240	I150-T236 HydrophobicContact CG2-CG2 3.85Å; V151-T236 HydrophobicContact CG2-CG2 4.46Å; I232-T236 VanDerWaalsContact O-CB 3.3Å; I232-T236 WeakPolarHBondContact O-CB 3.41Å; I232-T236 PolarHBondContact O-N 2.75Å; I232-T236 PolarHBondContact O-OG1 3.15Å; V233-T236 PolarHBondContact O-N 3.36Å; I234-T236 PolarHBondContact O-N 3.21Å; T236-K240 HydrophobicContact CG2-CD 4.22Å; T236-K240 WeakPolarHBondContact O-CB 3.28Å; T236-K240 WeakPolarHBondContact O-CG 3.41Å; T236-K240 PolarHBondContact O-N 3.08Å; T236-K240 VanDerWaalsContact O-N 3.07Å
237	I	90.1	Very high	89.7	Confident	40 Å²	40	74.6 Å²	74.6	21%	0.205	37%	0.374	C	S	.	.	H	α-helix	trans	-63.4	-45.6	175.9	-67.8	162.9	0	0	0	110.3	I150 V233 I234 K240 S241 I265 I273	I150-I237 HydrophobicContact CG2-CG1 4.13Å; V233-I237 HydrophobicContact CG1-CD1 3.76Å; V233-I237 WeakPolarHBondContact O-CD1 3.36Å; V233-I237 VanDerWaalsContact O-CG1 3.23Å; V233-I237 WeakPolarHBondContact O-CG1 3.47Å; V233-I237 PolarHBondContact O-N 2.99Å; I234-I237 WeakPolarHBondContact O-CB 3.46Å; I234-I237 PolarHBondContact O-N 3.17Å; I237-K240 PolarHBondContact O-N 3.47Å; I237-S241 WeakPolarHBondContact O-CB 3.29Å; I237-S241 PolarHBondContact O-N 3.02Å; I237-S241 PolarHBondContact O-OG 3.32Å; I237-I265 HydrophobicContact CB-CD1 4.49Å; I237-I265 HydrophobicContact CG1-CD1 3.91Å; I237-I265 HydrophobicContact CG2-CD1 4.25Å; I237-I273 HydrophobicContact CD1-CD1 3.82Å; I237-I273 HydrophobicContact CD1-CG2 4.2Å
238	W	90.8	Very high	88.8	Confident	183 Å²	183	75.5 Å²	75.5	69%	0.693	37%	0.374	S	S	*	.	H	α-helix	trans	-65.1	-41	-179.3	-78	62.5	0	0	0	112.7	I234 R235 S241 K242	I234-W238 PolarHBondContact O-N 3.35Å; R235-W238 PolarHBondContact O-N 3.33Å; W238-S241 WeakPolarHBondContact CA-OG 3.23Å; W238-S241 PolarHBondContact O-N 3.18Å; W238-S241 PolarHBondContact O-OG 3.13Å; W238-K242 WeakPolarHBondContact O-CB 3.48Å; W238-K242 PolarHBondContact O-N 2.61Å
239	I	90.5	Very high	87.9	Confident	91 Å²	91	75 Å²	75	47%	0.467	38%	0.378	S	S	.	.	H	α-helix	trans	-63.1	-47.5	174.8	-68.8	168	0	0	0	110.1	R235 S241 K242 T243	R235-I239 HydrophobicContact CG-CD1 3.84Å; R235-I239 HydrophobicContact CG-CG1 4.49Å; R235-I239 VanDerWaalsContact O-CG1 3.29Å; R235-I239 WeakPolarHBondContact O-CG1 3.29Å; R235-I239 PolarHBondContact O-N 3.16Å; I239-S241 PolarHBondContact O-N 3.39Å; I239-K242 PolarHBondContact O-N 2.86Å; I239-T243 PolarHBondContact O-N 3.15Å; I239-T243 PolarHBondContact O-OG1 3.03Å; I239-T243 VanDerWaalsContact O-OG1 3.08Å
240	K	86.3	Confident	87.1	Confident	92 Å²	92	79.1 Å²	79.1	40%	0.4	40%	0.401	S	S	.	.	H	α-helix	trans	-63.8	-37.8	179.4	-73.9	-179.6	178.2	-176.7	0	112.7	I150 T236 I237 Y244	I150-K240 PolarHBondContact O-NZ 3.25Å; T236-K240 HydrophobicContact CG2-CD 4.22Å; T236-K240 WeakPolarHBondContact O-CB 3.28Å; T236-K240 WeakPolarHBondContact O-CG 3.41Å; T236-K240 PolarHBondContact O-N 3.08Å; T236-K240 VanDerWaalsContact O-N 3.07Å; I237-K240 PolarHBondContact O-N 3.47Å; K240-Y244 WeakPolarHBondContact O-CB 3.27Å; K240-Y244 PolarHBondContact O-N 3.38Å; K240-Y244 VanDerWaalsContact O-N 3.08Å
241	S	86.2	Confident	86.1	Confident	60 Å²	60	80.8 Å²	80.8	42%	0.42	41%	0.414	S	S	.	.	H	α-helix	trans	-67.6	-41.1	176.7	61.7	0	0	0	0	111.9	I237 W238 I239 Y244 E245	I237-S241 WeakPolarHBondContact O-CB 3.29Å; I237-S241 PolarHBondContact O-N 3.02Å; I237-S241 PolarHBondContact O-OG 3.32Å; W238-S241 WeakPolarHBondContact CA-OG 3.23Å; W238-S241 PolarHBondContact O-N 3.18Å; W238-S241 PolarHBondContact O-OG 3.13Å; I239-S241 PolarHBondContact O-N 3.39Å; S241-Y244 WeakPolarHBondContact O-CB 3.21Å; S241-Y244 PolarHBondContact O-N 2.92Å; S241-E245 PolarHBondContact O-N 2.83Å
242	K	86.3	Confident	84.7	Confident	144 Å²	144	84.3 Å²	84.3	63%	0.626	43%	0.432	S	S	*	.	H	α-helix	trans	-64.5	-45.7	176.6	-173.9	171.9	-177.6	173.8	0	112	W238 I239 Y244 E245 T246	W238-K242 WeakPolarHBondContact O-CB 3.48Å; W238-K242 PolarHBondContact O-N 2.61Å; I239-K242 PolarHBondContact O-N 2.86Å; K242-Y244 VanDerWaalsContact C-N 3.27Å; K242-Y244 PolarHBondContact O-N 2.93Å; K242-E245 PolarHBondContact O-N 3.37Å; K242-T246 PolarHBondContact O-N 3.38Å; K242-T246 PolarHBondContact O-OG1 3.19Å
243	T	85.2	Confident	83.2	Confident	75 Å²	75	88 Å²	88	46%	0.46	45%	0.452	S	S	.	.	H	α-helix	trans	-59.5	-39.8	175.6	-56.1	0	0	0	0	111.6	I239 T246 V247	I239-T243 PolarHBondContact O-N 3.15Å; I239-T243 PolarHBondContact O-OG1 3.03Å; I239-T243 VanDerWaalsContact O-OG1 3.08Å; T243-T246 PolarHBondContact O-N 3.05Å; T243-V247 HydrophobicContact CG2-CG2 4.5Å; T243-V247 VanDerWaalsContact O-CG2 3.29Å; T243-V247 WeakPolarHBondContact O-CG2 3.38Å; T243-V247 PolarHBondContact O-N 3.4Å
244	Y	78.5	Confident	81.6	Confident	56 Å²	56	91.6 Å²	91.6	22%	0.22	49%	0.49	C	S	.	.	H	α-helix	trans	-63.5	-44.4	176.6	-177.9	-103	0	0	0	112.4	K240 S241 K242 V247 I248 Y260 N261	K240-Y244 WeakPolarHBondContact O-CB 3.27Å; K240-Y244 PolarHBondContact O-N 3.38Å; K240-Y244 VanDerWaalsContact O-N 3.08Å; S241-Y244 WeakPolarHBondContact O-CB 3.21Å; S241-Y244 PolarHBondContact O-N 2.92Å; K242-Y244 VanDerWaalsContact C-N 3.27Å; K242-Y244 PolarHBondContact O-N 2.93Å; Y244-V247 PolarHBondContact O-N 3.09Å; Y244-I248 HydrophobicContact CD1-CD1 3.75Å; Y244-I248 HydrophobicContact CE1-CD1 3.18Å; Y244-I248 HydrophobicContact CE1-CG1 4.35Å; Y244-I248 HydrophobicContact CE2-CD1 4.05Å; Y244-I248 HydrophobicContact CG-CD1 4.39Å; Y244-I248 WeakPolarHBondContact O-CG1 3.36Å; Y244-I248 PolarHBondContact O-N 3.03Å; Y244-Y260 HydrophobicContact CD2-CD1 4.16Å; Y244-Y260 HydrophobicContact CE2-CD1 4.37Å; Y244-N261 PolarHBondContact OH-OD1 3.33Å
245	E	81.7	Confident	80.1	Confident	140 Å²	140	97.6 Å²	97.6	65%	0.654	51%	0.513	S	S	*	.	H	α-helix	trans	-62.8	-40.1	176.1	-171.8	176.7	-172.4	0	0	112.4	S241 K242 I248 S249	S241-E245 PolarHBondContact O-N 2.83Å; K242-E245 PolarHBondContact O-N 3.37Å; E245-I248 PolarHBondContact O-N 3.2Å; E245-S249 PolarHBondContact O-N 3.42Å; E245-S249 PolarHBondContact O-OG 3.05Å
246	T	82.1	Confident	78.3	Confident	67 Å²	67	95.8 Å²	95.8	41%	0.411	52%	0.516	S	S	.	.	H	α-helix	trans	-66.3	-40.4	174.9	-51.4	0	0	0	0	112.6	K242 T243 S249 N250	K242-T246 PolarHBondContact O-N 3.38Å; K242-T246 PolarHBondContact O-OG1 3.19Å; T243-T246 PolarHBondContact O-N 3.05Å; T246-S249 WeakPolarHBondContact CA-OG 3.21Å; T246-S249 PolarHBondContact O-OG 2.89Å; T246-N250 WeakPolarHBondContact O-CB 3.33Å; T246-N250 PolarHBondContact O-N 3.17Å; T246-N250 VanDerWaalsContact O-N 3.17Å
247	V	79.8	Confident	76.7	Confident	41 Å²	41	96.3 Å²	96.3	25%	0.248	52%	0.52	C	S	.	.	H	α-helix	trans	-66.4	-40.4	177.3	170.9	0	0	0	0	111.1	T243 Y244 N250 C251 Y260	T243-V247 HydrophobicContact CG2-CG2 4.5Å; T243-V247 VanDerWaalsContact O-CG2 3.29Å; T243-V247 WeakPolarHBondContact O-CG2 3.38Å; T243-V247 PolarHBondContact O-N 3.4Å; Y244-V247 PolarHBondContact O-N 3.09Å; V247-N250 PolarHBondContact O-N 3.07Å; V247-C251 PolarHBondContact O-N 3.4Å; V247-C251 PolarHBondContact O-SG 2.91Å; V247-Y260 HydrophobicContact CB-CE1 4.5Å; V247-Y260 HydrophobicContact CG1-CD1 4.09Å; V247-Y260 HydrophobicContact CG1-CE1 4.12Å; V247-Y260 HydrophobicContact CG1-CG 4.32Å; V247-Y260 HydrophobicContact CG2-CE1 4.44Å
248	I	77.4	Confident	75.2	Confident	78 Å²	78	98.3 Å²	98.3	40%	0.4	54%	0.538	S	S	.	.	H	α-helix	trans	-65.4	-45.3	177.5	-73.1	177	0	0	0	111.7	Y244 E245 N250 C251	Y244-I248 HydrophobicContact CD1-CD1 3.75Å; Y244-I248 HydrophobicContact CE1-CD1 3.18Å; Y244-I248 HydrophobicContact CE1-CG1 4.35Å; Y244-I248 HydrophobicContact CE2-CD1 4.05Å; Y244-I248 HydrophobicContact CG-CD1 4.39Å; Y244-I248 WeakPolarHBondContact O-CG1 3.36Å; Y244-I248 PolarHBondContact O-N 3.03Å; E245-I248 PolarHBondContact O-N 3.2Å; I248-N250 VanDerWaalsContact C-N 3.28Å; I248-N250 PolarHBondContact O-N 3.34Å; I248-C251 PolarHBondContact O-N 3.16Å
249	S	78.5	Confident	73.6	Confident	82 Å²	82	93.2 Å²	93.2	57%	0.573	53%	0.53	S	S	*	.	H	α-helix	trans	-64.3	-31.6	-179.7	44.3	0	0	0	0	113.1	E245 T246	E245-S249 PolarHBondContact O-N 3.42Å; E245-S249 PolarHBondContact O-OG 3.05Å; T246-S249 WeakPolarHBondContact CA-OG 3.21Å; T246-S249 PolarHBondContact O-OG 2.89Å
250	N	76.9	Confident	71.9	Confident	125 Å²	125	94.9 Å²	94.9	67%	0.668	53%	0.531	S	S	*	.	H	α-helix	trans	-81.8	-16.1	177.9	-74.4	-11.6	0	0	0	114.5	T246 V247 I248 S252	T246-N250 WeakPolarHBondContact O-CB 3.33Å; T246-N250 PolarHBondContact O-N 3.17Å; T246-N250 VanDerWaalsContact O-N 3.17Å; V247-N250 PolarHBondContact O-N 3.07Å; I248-N250 VanDerWaalsContact C-N 3.28Å; I248-N250 PolarHBondContact O-N 3.34Å; N250-S252 PolarHBondContact O-N 3.44Å
251	C	74.1	Confident	70.3	Confident	47 Å²	47	95.2 Å²	95.2	32%	0.318	54%	0.537	S	S	.	.			trans	-87.6	88.8	179	-74.6	0	0	0	0	110.7	V247 I248 D253 C257	V247-C251 PolarHBondContact O-N 3.4Å; V247-C251 PolarHBondContact O-SG 2.91Å; I248-C251 PolarHBondContact O-N 3.16Å; C251-D253 VanDerWaalsContact C-N 3.28Å; C251-D253 PolarHBondContact O-N 3.3Å; C251-C257 WeakPolarHBondContact CB-SG 3.32Å; C251-C257 VanDerWaalsContact SG-SG 3.68Å
252	S	66.6	Low	68.8	Low	118 Å²	118	103.2 Å²	103.2	83%	0.825	56%	0.558	S	S	*	*			trans	-71.6	-19	173.8	-54.4	0	0	0	0	113.8	N250	N250-S252 PolarHBondContact O-N 3.44Å
253	D	62.1	Low	67.4	Low	135 Å²	135	98.8 Å²	98.8	72%	0.722	55%	0.554	S	S	*	*	S	Bend	trans	-93.3	104.8	178.7	-90	-39.3	0	0	0	111.9	C251 K255 L256	C251-D253 VanDerWaalsContact C-N 3.28Å; C251-D253 PolarHBondContact O-N 3.3Å; D253-K255 PolarHBondContact O-N 3.31Å; D253-L256 PolarHBondContact O-N 2.98Å
254	G	60.1	Low	66.4	Low	76 Å²	76	100.3 Å²	100.3	78%	0.784	56%	0.559	S	S	*	*	T	Hydrogen-bonded Turn	trans	-58	3.2	-174.3	0	0	0	0	0	117.4
255	K	61.5	Low	66	Low	197 Å²	197	99.1 Å²	99.1	86%	0.857	56%	0.556	S	S	*	*	T	Hydrogen-bonded Turn	trans	-100.6	-29	179.6	-73.2	-179.1	179	175.6	0	114.7	D253	D253-K255 PolarHBondContact O-N 3.31Å
256	L	58.3	Low	65.8	Low	138 Å²	138	95.3 Å²	95.3	72%	0.723	55%	0.545	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.9	-25.6	-176.2	-158	73.3	0	0	0	113.5	D253 S258	D253-L256 PolarHBondContact O-N 2.98Å; L256-S258 VanDerWaalsContact C-N 3.31Å; L256-S258 PolarHBondContact O-N 3.45Å
257	C	58.8	Low	65.8	Low	37 Å²	37	101.3 Å²	101.3	25%	0.25	57%	0.565	C	S	.	*	H	α-helix	trans	-64.4	-26.9	-177.8	-79.4	0	0	0	0	115.3	C251 S259 Y260	C251-C257 WeakPolarHBondContact CB-SG 3.32Å; C251-C257 VanDerWaalsContact SG-SG 3.68Å; C257-S259 PolarHBondContact O-N 3.28Å; C257-Y260 PolarHBondContact O-N 3.33Å; C257-Y260 VanDerWaalsContact O-N 3.13Å
258	S	57.5	Low	65.8	Low	82 Å²	82	102.7 Å²	102.7	57%	0.573	58%	0.581	S	S	*	*	H	α-helix	trans	-63.7	-30.1	-175.1	72.2	0	0	0	0	112.5	L256 N261	L256-S258 VanDerWaalsContact C-N 3.31Å; L256-S258 PolarHBondContact O-N 3.45Å; S258-N261 WeakPolarHBondContact O-CB 3.29Å; S258-N261 PolarHBondContact O-ND2 3.17Å
259	S	57.8	Low	66.1	Low	76 Å²	76	102.1 Å²	102.1	53%	0.531	58%	0.575	S	S	.	*	H	α-helix	trans	-72.6	-31	177.7	-169.9	0	0	0	0	112.5	C257 N261 R262	C257-S259 PolarHBondContact O-N 3.28Å; S259-N261 PolarHBondContact O-N 3.43Å; S259-R262 PolarHBondContact O-N 3.32Å
260	Y	55.3	Low	66.5	Low	126 Å²	126	101.3 Å²	101.3	49%	0.494	56%	0.564	S	S	.	*	H	α-helix	trans	-74.5	-7.8	179.4	-132.6	-98.2	0	0	0	113.8	Y244 V247 C257 R262 G263	Y244-Y260 HydrophobicContact CD2-CD1 4.16Å; Y244-Y260 HydrophobicContact CE2-CD1 4.37Å; V247-Y260 HydrophobicContact CB-CE1 4.5Å; V247-Y260 HydrophobicContact CG1-CD1 4.09Å; V247-Y260 HydrophobicContact CG1-CE1 4.12Å; V247-Y260 HydrophobicContact CG1-CG 4.32Å; V247-Y260 HydrophobicContact CG2-CE1 4.44Å; C257-Y260 PolarHBondContact O-N 3.33Å; C257-Y260 VanDerWaalsContact O-N 3.13Å; Y260-R262 PolarHBondContact O-N 3.33Å; Y260-G263 PolarHBondContact O-N 3.21Å
261	N	51.9	Low	66.9	Low	99 Å²	99	96.9 Å²	96.9	53%	0.529	54%	0.539	S	S	.	.	G	3₁₀ helix	trans	-53.5	-19.1	167	-83.9	-46.1	0	0	0	113.1	Y244 S258 S259 G263 L264	Y244-N261 PolarHBondContact OH-OD1 3.33Å; S258-N261 WeakPolarHBondContact O-CB 3.29Å; S258-N261 PolarHBondContact O-ND2 3.17Å; S259-N261 PolarHBondContact O-N 3.43Å; N261-G263 PolarHBondContact O-N 3.31Å; N261-L264 PolarHBondContact O-N 2.64Å
262	R	53.5	Low	67.7	Low	228 Å²	228	94.8 Å²	94.8	86%	0.86	53%	0.525	S	S	*	.	G	3₁₀ helix	trans	-65.3	-18.9	172.1	-76.9	-178.3	161.1	146	-3.9	114.2	S259 Y260 L264	S259-R262 PolarHBondContact O-N 3.32Å; Y260-R262 PolarHBondContact O-N 3.33Å; R262-L264 VanDerWaalsContact C-N 3.34Å
263	G	58.2	Low	68.8	Low	52 Å²	52	89.7 Å²	89.7	54%	0.536	49%	0.488	S	S	.	.	G	3₁₀ helix	trans	-76	-17.2	178.2	0	0	0	0	0	114.5	Y260 N261 I265	Y260-G263 PolarHBondContact O-N 3.21Å; N261-G263 PolarHBondContact O-N 3.31Å; G263-I265 PolarHBondContact O-N 3.06Å
264	L	64.6	Low	70.3	Confident	106 Å²	106	89.2 Å²	89.2	56%	0.555	48%	0.48	S	S	*	.	S	Bend	trans	-70.8	126.3	-178.7	-171.7	63.4	0	0	0	110.6	N261 R262 S266	N261-L264 PolarHBondContact O-N 2.64Å; R262-L264 VanDerWaalsContact C-N 3.34Å; L264-S266 PolarHBondContact O-N 3.17Å; L264-S266 VanDerWaalsContact O-N 3.12Å
265	I	70	Confident	71.8	Confident	32 Å²	32	85.8 Å²	85.8	16%	0.164	44%	0.443	C	S	.	.	P	Polyproline II helix	trans	-54	121.3	171.1	-61.8	174.2	0	0	0	107.8	I150 I237 G263 K269 I270	I150-I265 HydrophobicContact CD1-CG2 4.38Å; I237-I265 HydrophobicContact CB-CD1 4.49Å; I237-I265 HydrophobicContact CG1-CD1 3.91Å; I237-I265 HydrophobicContact CG2-CD1 4.25Å; G263-I265 PolarHBondContact O-N 3.06Å; I265-K269 HydrophobicContact CG2-CB 3.4Å; I265-K269 VanDerWaalsContact CG2-CB 3.4Å; I265-K269 HydrophobicContact CG2-CD 4.08Å; I265-K269 HydrophobicContact CG2-CG 4.39Å; I265-I270 HydrophobicContact CB-CD1 4.5Å; I265-I270 HydrophobicContact CB-CG1 4.12Å; I265-I270 HydrophobicContact CG2-CG1 3.77Å
266	S	77.6	Confident	73.3	Confident	60 Å²	60	76.4 Å²	76.4	42%	0.42	40%	0.403	S	S	.	.	P	Polyproline II helix	trans	-53.5	145.5	-175.3	72.8	0	0	0	0	111.7	L264 A268 K269 I270	L264-S266 PolarHBondContact O-N 3.17Å; L264-S266 VanDerWaalsContact O-N 3.12Å; S266-A268 PolarHBondContact O-N 3.24Å; S266-K269 WeakPolarHBondContact O-CA 3.36Å; S266-K269 WeakPolarHBondContact O-CB 3.46Å; S266-K269 PolarHBondContact O-N 3.13Å; S266-K269 WeakPolarHBondContact OG-CG 3.37Å; S266-K269 PolarHBondContact OG-N 3.3Å; S266-I270 PolarHBondContact O-N 3.28Å; S266-I270 VanDerWaalsContact O-N 3.08Å
267	K	80.5	Confident	75.1	Confident	193 Å²	193	72.5 Å²	72.5	84%	0.839	38%	0.382	S	S	*	.	H	α-helix	trans	-49.9	-36.7	178.5	-65.9	-176.5	179.4	-179.5	0	112.1	K271	K267-K271 VanDerWaalsContact O-CB 3.28Å; K267-K271 WeakPolarHBondContact O-CB 3.25Å; K267-K271 PolarHBondContact O-N 3.39Å
268	A	80.7	Confident	76.8	Confident	70 Å²	70	74.2 Å²	74.2	58%	0.579	39%	0.388	S	S	*	.	H	α-helix	trans	-65	-40	175.8	0	0	0	0	0	113.4	S266 A272	S266-A268 PolarHBondContact O-N 3.24Å; A268-A272 WeakPolarHBondContact O-CB 3.44Å; A268-A272 PolarHBondContact O-N 3.42Å; A268-A272 VanDerWaalsContact O-N 3.07Å
269	K	83.9	Confident	78.6	Confident	65 Å²	65	70.4 Å²	70.4	28%	0.283	36%	0.361	S	S	.	.	H	α-helix	trans	-67.1	-46.2	175.6	-77.3	-177	-178.1	-167.2	0	111.3	A149 I150 I265 S266 K271 A272 I273	A149-K269 PolarHBondContact O-NZ 3.36Å; I150-K269 HydrophobicContact CD1-CD 4.43Å; I265-K269 HydrophobicContact CG2-CB 3.4Å; I265-K269 VanDerWaalsContact CG2-CB 3.4Å; I265-K269 HydrophobicContact CG2-CD 4.08Å; I265-K269 HydrophobicContact CG2-CG 4.39Å; S266-K269 WeakPolarHBondContact O-CA 3.36Å; S266-K269 WeakPolarHBondContact O-CB 3.46Å; S266-K269 PolarHBondContact O-N 3.13Å; S266-K269 WeakPolarHBondContact OG-CG 3.37Å; S266-K269 PolarHBondContact OG-N 3.3Å; K269-K271 VanDerWaalsContact C-N 3.31Å; K269-K271 PolarHBondContact O-N 3.16Å; K269-A272 PolarHBondContact O-N 3.11Å; K269-I273 WeakPolarHBondContact O-CD1 3.5Å; K269-I273 VanDerWaalsContact O-CG1 3.27Å; K269-I273 WeakPolarHBondContact O-CG1 3.31Å; K269-I273 PolarHBondContact O-N 3.12Å
270	I	85.8	Confident	80.4	Confident	65 Å²	65	67.3 Å²	67.3	33%	0.333	34%	0.338	S	S	.	.	H	α-helix	trans	-57	-47.6	177	-64.4	177.3	0	0	0	110.4	I265 S266 A272 I273 K274	I265-I270 HydrophobicContact CB-CD1 4.5Å; I265-I270 HydrophobicContact CB-CG1 4.12Å; I265-I270 HydrophobicContact CG2-CG1 3.77Å; S266-I270 PolarHBondContact O-N 3.28Å; S266-I270 VanDerWaalsContact O-N 3.08Å; I270-A272 VanDerWaalsContact C-N 3.32Å; I270-A272 PolarHBondContact O-N 3.12Å; I270-I273 PolarHBondContact O-N 2.87Å; I270-K274 HydrophobicContact CG2-CD 4.39Å; I270-K274 HydrophobicContact CG2-CG 4.48Å; I270-K274 WeakPolarHBondContact O-CG 3.3Å; I270-K274 PolarHBondContact O-N 3.31Å
271	K	87.2	Confident	82.3	Confident	32 Å²	32	65.8 Å²	65.8	14%	0.139	34%	0.338	C	S	.	.	H	α-helix	trans	-58.2	-43.9	177.9	-179.8	173.5	-179.3	136.1	0	112.9	K267 K269 I273 K274 Y275 F333 S336 I337	K267-K271 VanDerWaalsContact O-CB 3.28Å; K267-K271 WeakPolarHBondContact O-CB 3.25Å; K267-K271 PolarHBondContact O-N 3.39Å; K269-K271 VanDerWaalsContact C-N 3.31Å; K269-K271 PolarHBondContact O-N 3.16Å; K271-I273 VanDerWaalsContact C-N 3.32Å; K271-I273 PolarHBondContact O-N 3.41Å; K271-K274 PolarHBondContact O-N 2.97Å; K271-Y275 PolarHBondContact O-N 3.07Å; K271-F333 WeakPolarHBondContact CE-O 3.34Å; K271-F333 HydrophobicContact CG-CD1 4.29Å; K271-F333 PolarHBondContact NZ-O 3.16Å; K271-S336 PolarHBondContact NZ-OG 3.31Å; K271-I337 HydrophobicContact CD-CD1 4.05Å; K271-I337 HydrophobicContact CD-CG1 4.44Å; K271-I337 VanDerWaalsContact NZ-CD1 3.25Å
272	A	89.2	Confident	84.5	Confident	3 Å²	3	61.6 Å²	61.6	3%	0.025	32%	0.317	C	S	.	.	H	α-helix	trans	-68.3	-31.6	179	0	0	0	0	0	113	M83 A268 K269 I270 S276	M83-A272 HydrophobicContact CB-CB 4.26Å; M83-A272 HydrophobicContact CE-CB 4.33Å; M83-A272 HydrophobicContact CG-CB 4.06Å; M83-A272 HydrophobicContact SD-CB 3.51Å; M83-A272 VanDerWaalsContact SD-CB 3.51Å; A268-A272 WeakPolarHBondContact O-CB 3.44Å; A268-A272 PolarHBondContact O-N 3.42Å; A268-A272 VanDerWaalsContact O-N 3.07Å; K269-A272 PolarHBondContact O-N 3.11Å; I270-A272 VanDerWaalsContact C-N 3.32Å; I270-A272 PolarHBondContact O-N 3.12Å; A272-S276 WeakPolarHBondContact O-CB 3.42Å; A272-S276 PolarHBondContact O-N 3.22Å; A272-S276 VanDerWaalsContact O-N 3.13Å; A272-S276 PolarHBondContact O-OG 3.34Å
273	I	90.7	Very high	86.5	Confident	11 Å²	11	50.8 Å²	50.8	6%	0.056	28%	0.277	C	S	.	.	H	α-helix	trans	-70.1	-43.8	173.2	-64.4	159.3	0	0	0	110.7	I150 I237 K269 I270 K271 Y275 S276 I277	I150-I273 HydrophobicContact CD1-CD1 3.71Å; I150-I273 HydrophobicContact CG1-CD1 4.08Å; I237-I273 HydrophobicContact CD1-CD1 3.82Å; I237-I273 HydrophobicContact CD1-CG2 4.2Å; K269-I273 WeakPolarHBondContact O-CD1 3.5Å; K269-I273 VanDerWaalsContact O-CG1 3.27Å; K269-I273 WeakPolarHBondContact O-CG1 3.31Å; K269-I273 PolarHBondContact O-N 3.12Å; I270-I273 PolarHBondContact O-N 2.87Å; K271-I273 VanDerWaalsContact C-N 3.32Å; K271-I273 PolarHBondContact O-N 3.41Å; I273-Y275 PolarHBondContact O-N 2.79Å; I273-S276 WeakPolarHBondContact CA-OG 3.4Å; I273-S276 PolarHBondContact O-N 2.81Å; I273-S276 PolarHBondContact O-OG 3.37Å; I273-I277 HydrophobicContact CG2-CD1 3.82Å; I273-I277 HydrophobicContact CG2-CG1 4.37Å; I273-I277 VanDerWaalsContact O-CG1 3.29Å; I273-I277 WeakPolarHBondContact O-CG1 3.22Å; I273-I277 PolarHBondContact O-N 2.92Å
274	K	92.4	Very high	88.3	Confident	125 Å²	125	50.6 Å²	50.6	54%	0.543	26%	0.262	S	S	.	.	H	α-helix	trans	-60.4	-46	176.5	-71.3	-174.5	175.8	-169.4	0	111.4	I270 K271 S276 I277 I278 F333	I270-K274 HydrophobicContact CG2-CD 4.39Å; I270-K274 HydrophobicContact CG2-CG 4.48Å; I270-K274 WeakPolarHBondContact O-CG 3.3Å; I270-K274 PolarHBondContact O-N 3.31Å; K271-K274 PolarHBondContact O-N 2.97Å; K274-S276 VanDerWaalsContact C-N 3.31Å; K274-S276 PolarHBondContact O-N 3.34Å; K274-I277 PolarHBondContact O-N 2.84Å; K274-I278 WeakPolarHBondContact O-CG1 3.27Å; K274-I278 PolarHBondContact O-N 2.9Å; K274-I278 VanDerWaalsContact O-N 3.07Å; K274-F333 VanDerWaalsContact C-CZ 3.46Å; K274-F333 HydrophobicContact CB-CE1 3.45Å; K274-F333 VanDerWaalsContact CB-CE1 3.45Å; K274-F333 HydrophobicContact CB-CZ 3.8Å
275	Y	92.5	Very high	89.8	Confident	5 Å²	5	49.8 Å²	49.8	2%	0.02	27%	0.265	C	S	.	.	H	α-helix	trans	-55.6	-47.9	174.6	168.5	-96.8	0	0	0	112	M83 V87 L142 K271 I273 I278 I279 I329 F333	M83-Y275 HydrophobicContact CE-CD1 3.43Å; M83-Y275 VanDerWaalsContact CE-CD1 3.43Å; M83-Y275 HydrophobicContact CE-CD2 3.89Å; M83-Y275 HydrophobicContact CE-CE1 4.15Å; M83-Y275 HydrophobicContact CE-CG 3.25Å; V87-Y275 HydrophobicContact CG2-CE1 3.89Å; V87-Y275 HydrophobicContact CG2-CE2 4.47Å; V87-Y275 WeakPolarHBondContact CG2-OH 3.22Å; L142-Y275 HydrophobicContact CD2-CE1 4.42Å; K271-Y275 PolarHBondContact O-N 3.07Å; I273-Y275 PolarHBondContact O-N 2.79Å; Y275-I278 PolarHBondContact O-N 2.85Å; Y275-I279 HydrophobicContact CE1-CD1 3.72Å; Y275-I279 HydrophobicContact CE2-CD1 3.69Å; Y275-I279 HydrophobicContact CE2-CG1 4.3Å; Y275-I279 PolarHBondContact O-N 3.13Å; Y275-I279 WeakPolarHBondContact OH-CD1 3.33Å; Y275-I329 HydrophobicContact CD2-CG2 3.8Å; Y275-I329 HydrophobicContact CE2-CG2 3.92Å; Y275-F333 HydrophobicContact CD2-CB 4.23Å; Y275-F333 AromaticContact CD2-CD2 3.74Å; Y275-F333 HydrophobicContact CD2-CD2 3.74Å; Y275-F333 HydrophobicContact CD2-CE2 4.44Å; Y275-F333 HydrophobicContact CD2-CG 4.15Å; Y275-F333 HydrophobicContact CG-CD2 4.32Å
276	S	93.4	Very high	91.1	Very high	0 Å²	0	48.6 Å²	48.6	0%	0	26%	0.259	C	S	.	.	H	α-helix	trans	-71.2	-35.3	-174.6	68.2	0	0	0	0	112.3	Y230 A272 I273 K274 I279 I280	Y230-S276 WeakPolarHBondContact OH-CB 3.16Å; Y230-S276 PolarHBondContact OH-OG 3.37Å; A272-S276 WeakPolarHBondContact O-CB 3.42Å; A272-S276 PolarHBondContact O-N 3.22Å; A272-S276 VanDerWaalsContact O-N 3.13Å; A272-S276 PolarHBondContact O-OG 3.34Å; I273-S276 WeakPolarHBondContact CA-OG 3.4Å; I273-S276 PolarHBondContact O-N 2.81Å; I273-S276 PolarHBondContact O-OG 3.37Å; K274-S276 VanDerWaalsContact C-N 3.31Å; K274-S276 PolarHBondContact O-N 3.34Å; S276-I279 PolarHBondContact O-N 3.04Å; S276-I280 WeakPolarHBondContact O-CB 3.45Å; S276-I280 VanDerWaalsContact O-CD1 3.24Å; S276-I280 WeakPolarHBondContact O-CD1 3.47Å; S276-I280 WeakPolarHBondContact O-CG1 3.31Å; S276-I280 PolarHBondContact O-N 3.09Å
277	I	95	Very high	92	Very high	55 Å²	55	46.4 Å²	46.4	28%	0.282	24%	0.242	S	C	.	.	H	α-helix	trans	-58.7	-49.3	169.3	-69.6	169.1	0	0	0	110.7	Y230 I273 K274 I279 I280 L281	Y230-I277 HydrophobicContact CD1-CG1 3.82Å; Y230-I277 HydrophobicContact CE1-CG1 3.72Å; I273-I277 HydrophobicContact CG2-CD1 3.82Å; I273-I277 HydrophobicContact CG2-CG1 4.37Å; I273-I277 VanDerWaalsContact O-CG1 3.29Å; I273-I277 WeakPolarHBondContact O-CG1 3.22Å; I273-I277 PolarHBondContact O-N 2.92Å; K274-I277 PolarHBondContact O-N 2.84Å; I277-I279 PolarHBondContact O-N 3.08Å; I277-I280 PolarHBondContact O-N 3.48Å; I277-L281 HydrophobicContact CG2-CD1 3.96Å; I277-L281 HydrophobicContact CG2-CG 4.37Å; I277-L281 WeakPolarHBondContact O-CG 3.36Å; I277-L281 PolarHBondContact O-N 3.34Å
278	I	96	Very high	92.8	Very high	74 Å²	74	38.1 Å²	38.1	38%	0.379	21%	0.208	S	C	.	.	H	α-helix	trans	-63.5	-41.6	-177.5	-66.3	-165.5	0	0	0	111.5	K274 Y275 I280 L281 A282 I329 F333	K274-I278 WeakPolarHBondContact O-CG1 3.27Å; K274-I278 PolarHBondContact O-N 2.9Å; K274-I278 VanDerWaalsContact O-N 3.07Å; Y275-I278 PolarHBondContact O-N 2.85Å; I278-I280 VanDerWaalsContact C-N 3.33Å; I278-I280 PolarHBondContact O-N 2.91Å; I278-L281 PolarHBondContact O-N 2.99Å; I278-A282 PolarHBondContact O-N 2.96Å; I278-I329 HydrophobicContact CB-CG2 4.28Å; I278-I329 HydrophobicContact CG2-CD1 3.99Å; I278-I329 HydrophobicContact CG2-CG1 3.94Å; I278-I329 HydrophobicContact CG2-CG2 3.83Å; I278-F333 HydrophobicContact CB-CE2 4.15Å; I278-F333 HydrophobicContact CD1-CE2 3.65Å; I278-F333 HydrophobicContact CD1-CZ 3.53Å; I278-F333 HydrophobicContact CG1-CE2 4.15Å; I278-F333 HydrophobicContact CG1-CZ 4.07Å
279	I	94.8	Very high	93.6	Very high	1 Å²	1	37.1 Å²	37.1	1%	0.005	20%	0.196	C	C	.	.	H	α-helix	trans	-63.3	-38.9	175.6	-91	-169	0	0	0	112.4	L90 L139 Y275 S276 I277 A282 F283 I329	L90-I279 HydrophobicContact CD2-CD1 3.61Å; L139-I279 HydrophobicContact CD1-CG2 4.46Å; L139-I279 HydrophobicContact CD2-CG2 3.19Å; L139-I279 HydrophobicContact CG-CG2 4.44Å; Y275-I279 HydrophobicContact CE1-CD1 3.72Å; Y275-I279 HydrophobicContact CE2-CD1 3.69Å; Y275-I279 HydrophobicContact CE2-CG1 4.3Å; Y275-I279 PolarHBondContact O-N 3.13Å; Y275-I279 WeakPolarHBondContact OH-CD1 3.33Å; S276-I279 PolarHBondContact O-N 3.04Å; I277-I279 PolarHBondContact O-N 3.08Å; I279-A282 PolarHBondContact O-N 2.97Å; I279-F283 PolarHBondContact O-N 2.79Å; I279-I329 HydrophobicContact CG1-CB 4.43Å; I279-I329 HydrophobicContact CG1-CD1 3.74Å; I279-I329 HydrophobicContact CG1-CG2 4.02Å
280	I	94.6	Very high	94.2	Very high	12 Å²	12	36.9 Å²	36.9	6%	0.062	19%	0.194	C	C	.	.	H	α-helix	trans	-67.7	-40.7	178.1	-72.8	161.2	0	0	0	110.9	I226 Y230 S276 I277 I278 A282 F283 I284	I226-I280 HydrophobicContact CG2-CB 4.28Å; I226-I280 HydrophobicContact CG2-CD1 3.57Å; I226-I280 HydrophobicContact CG2-CG1 3.78Å; I226-I280 HydrophobicContact CG2-CG2 3.52Å; Y230-I280 HydrophobicContact CD1-CD1 4.36Å; Y230-I280 HydrophobicContact CD2-CD1 3.47Å; Y230-I280 VanDerWaalsContact CD2-CD1 3.47Å; Y230-I280 HydrophobicContact CE1-CD1 3.94Å; Y230-I280 HydrophobicContact CE2-CD1 2.96Å; Y230-I280 HydrophobicContact CE2-CG1 4.45Å; Y230-I280 HydrophobicContact CG-CD1 4.14Å; Y230-I280 WeakPolarHBondContact OH-CD1 3.21Å; S276-I280 WeakPolarHBondContact O-CB 3.45Å; S276-I280 VanDerWaalsContact O-CD1 3.24Å; S276-I280 WeakPolarHBondContact O-CD1 3.47Å; S276-I280 WeakPolarHBondContact O-CG1 3.31Å; S276-I280 PolarHBondContact O-N 3.09Å; I277-I280 PolarHBondContact O-N 3.48Å; I278-I280 VanDerWaalsContact C-N 3.33Å; I278-I280 PolarHBondContact O-N 2.91Å; I280-A282 VanDerWaalsContact C-N 3.31Å; I280-A282 PolarHBondContact O-N 3.48Å; I280-F283 WeakPolarHBondContact O-CB 3.37Å; I280-F283 PolarHBondContact O-N 2.67Å; I280-I284 HydrophobicContact CG2-CD1 3.95Å; I280-I284 VanDerWaalsContact O-CG1 3.29Å; I280-I284 WeakPolarHBondContact O-CG1 3.32Å; I280-I284 PolarHBondContact O-N 2.67Å
281	L	96.3	Very high	94.7	Very high	94 Å²	94	34 Å²	34	49%	0.492	18%	0.178	S	C	.	.	H	α-helix	trans	-61.9	-41.9	173.4	-67.8	173.7	0	0	0	111	I277 I278 F283 I284 C285	I277-L281 HydrophobicContact CG2-CD1 3.96Å; I277-L281 HydrophobicContact CG2-CG 4.37Å; I277-L281 WeakPolarHBondContact O-CG 3.36Å; I277-L281 PolarHBondContact O-N 3.34Å; I278-L281 PolarHBondContact O-N 2.99Å; L281-F283 VanDerWaalsContact C-N 3.34Å; L281-F283 PolarHBondContact O-N 3.37Å; L281-I284 PolarHBondContact O-N 3.34Å; L281-C285 WeakPolarHBondContact O-CB 3.12Å; L281-C285 PolarHBondContact O-N 3.26Å; L281-C285 PolarHBondContact O-SG 3.43Å
282	A	96.6	Very high	95.1	Very high	11 Å²	11	36.7 Å²	36.7	9%	0.091	19%	0.194	C	C	.	.	H	α-helix	trans	-62.4	-40.4	174.6	0	0	0	0	0	112.3	I278 I279 I280 C286 I325 I329	I278-A282 PolarHBondContact O-N 2.96Å; I279-A282 PolarHBondContact O-N 2.97Å; I280-A282 VanDerWaalsContact C-N 3.31Å; I280-A282 PolarHBondContact O-N 3.48Å; A282-C286 WeakPolarHBondContact O-CB 3.32Å; A282-C286 PolarHBondContact O-N 3.45Å; A282-C286 PolarHBondContact O-SG 3.17Å; A282-I325 HydrophobicContact CB-CG2 4.03Å; A282-I329 HydrophobicContact CB-CD1 3.95Å
283	F	96	Very high	95.4	Very high	1 Å²	1	38.2 Å²	38.2	0%	0.004	20%	0.2	C	C	.	.	H	α-helix	trans	-57.6	-51.4	171.8	171.4	-94.9	0	0	0	111.2	T136 L139 Y219 I279 I280 L281 C285 C286 W287 N322	T136-F283 HydrophobicContact CG2-CE2 4.28Å; T136-F283 HydrophobicContact CG2-CZ 4.26Å; L139-F283 HydrophobicContact CD1-CB 3.79Å; L139-F283 HydrophobicContact CD1-CD2 3.57Å; L139-F283 HydrophobicContact CD1-CE2 4.37Å; L139-F283 HydrophobicContact CD1-CG 3.79Å; Y219-F283 HydrophobicContact CD2-CE1 4.08Å; Y219-F283 HydrophobicContact CD2-CZ 4.05Å; Y219-F283 HydrophobicContact CE2-CE1 4.35Å; I279-F283 PolarHBondContact O-N 2.79Å; I280-F283 WeakPolarHBondContact O-CB 3.37Å; I280-F283 PolarHBondContact O-N 2.67Å; L281-F283 VanDerWaalsContact C-N 3.34Å; L281-F283 PolarHBondContact O-N 3.37Å; F283-C285 PolarHBondContact O-N 2.88Å; F283-C286 PolarHBondContact O-N 2.87Å; F283-W287 AromaticContact CD2-CD1 3.18Å; F283-W287 HydrophobicContact CD2-CG 4.06Å; F283-W287 AromaticContact CD2-NE1 3.67Å; F283-W287 HydrophobicContact CE2-CB 4.41Å; F283-W287 AromaticContact CE2-CD1 3.38Å; F283-W287 AromaticContact CE2-CG 3.88Å; F283-W287 HydrophobicContact CE2-CG 3.88Å; F283-W287 AromaticContact CE2-NE1 3.78Å; F283-W287 AromaticContact CG-CD1 3.94Å; F283-W287 HydrophobicContact CZ-CG 4.43Å; F283-W287 VanDerWaalsContact O-CB 3.27Å; F283-W287 WeakPolarHBondContact O-CB 3.36Å; F283-W287 PolarHBondContact O-N 3.34Å; F283-N322 WeakPolarHBondContact CA-ND2 3.29Å
284	I	96.8	Very high	95.6	Very high	47 Å²	47	38.7 Å²	38.7	24%	0.241	20%	0.203	C	C	.	.	H	α-helix	trans	-59.8	-51.3	178.8	-65.7	167.3	0	0	0	110.4	L223 I280 L281 C286 W287 S288	L223-I284 HydrophobicContact CD1-CD1 3.74Å; L223-I284 HydrophobicContact CD1-CG1 3.56Å; I280-I284 HydrophobicContact CG2-CD1 3.95Å; I280-I284 VanDerWaalsContact O-CG1 3.29Å; I280-I284 WeakPolarHBondContact O-CG1 3.32Å; I280-I284 PolarHBondContact O-N 2.67Å; L281-I284 PolarHBondContact O-N 3.34Å; I284-C286 VanDerWaalsContact C-N 3.3Å; I284-C286 PolarHBondContact O-N 3.47Å; I284-W287 PolarHBondContact O-N 2.93Å; I284-S288 WeakPolarHBondContact CG2-OG 3.36Å; I284-S288 VanDerWaalsContact O-CB 3.25Å; I284-S288 WeakPolarHBondContact O-CB 3.21Å; I284-S288 PolarHBondContact O-N 3.01Å; I284-S288 PolarHBondContact O-OG 2.94Å
285	C	96.9	Very high	95.8	Very high	89 Å²	89	34.2 Å²	34.2	60%	0.601	19%	0.185	S	C	*	.	H	α-helix	trans	-63.2	-34.2	-176.8	-67.4	0	0	0	0	113.3	L281 F283 P289	L281-C285 WeakPolarHBondContact O-CB 3.12Å; L281-C285 PolarHBondContact O-N 3.26Å; L281-C285 PolarHBondContact O-SG 3.43Å; F283-C285 PolarHBondContact O-N 2.88Å; C285-P289 VanDerWaalsContact O-CD 3.27Å; C285-P289 WeakPolarHBondContact O-CD 3.28Å
286	C	96.4	Very high	95.9	Very high	7 Å²	7	37.4 Å²	37.4	5%	0.047	20%	0.202	C	C	.	.	H	α-helix	trans	-83.3	-39.8	179.7	-61.7	0	0	0	0	112.5	A282 F283 I284 L318 N322	A282-C286 WeakPolarHBondContact O-CB 3.32Å; A282-C286 PolarHBondContact O-N 3.45Å; A282-C286 PolarHBondContact O-SG 3.17Å; F283-C286 PolarHBondContact O-N 2.87Å; I284-C286 VanDerWaalsContact C-N 3.3Å; I284-C286 PolarHBondContact O-N 3.47Å; C286-L318 HydrophobicContact CB-CB 4.48Å; C286-L318 WeakPolarHBondContact CB-O 3.33Å; C286-L318 WeakPolarHBondContact O-CB 3.41Å; C286-N322 HydrophobicContact CB-CB 3.69Å
287	W	96.9	Very high	95.9	Very high	14 Å²	14	39.4 Å²	39.4	5%	0.053	21%	0.212	C	C	.	.	H	α-helix	trans	-89.4	-29.6	-173	-75.3	103.1	0	0	0	114.3	L132 Y219 F283 I284 Y290 F291 P319 N322	L132-W287 HydrophobicContact CD1-CH2 3Å; L132-W287 HydrophobicContact CD1-CZ2 3.42Å; L132-W287 VanDerWaalsContact CD1-CZ2 3.42Å; L132-W287 HydrophobicContact CD1-CZ3 3.76Å; L132-W287 HydrophobicContact CG-CH2 4.42Å; Y219-W287 HydrophobicContact CD2-CB 3.85Å; Y219-W287 HydrophobicContact CE2-CB 4.05Å; F283-W287 AromaticContact CD2-CD1 3.18Å; F283-W287 HydrophobicContact CD2-CG 4.06Å; F283-W287 AromaticContact CD2-NE1 3.67Å; F283-W287 HydrophobicContact CE2-CB 4.41Å; F283-W287 AromaticContact CE2-CD1 3.38Å; F283-W287 AromaticContact CE2-CG 3.88Å; F283-W287 HydrophobicContact CE2-CG 3.88Å; F283-W287 AromaticContact CE2-NE1 3.78Å; F283-W287 AromaticContact CG-CD1 3.94Å; F283-W287 HydrophobicContact CZ-CG 4.43Å; F283-W287 VanDerWaalsContact O-CB 3.27Å; F283-W287 WeakPolarHBondContact O-CB 3.36Å; F283-W287 PolarHBondContact O-N 3.34Å; I284-W287 PolarHBondContact O-N 2.93Å; W287-Y290 AromaticContact CE3-CD1 3.8Å; W287-Y290 HydrophobicContact CE3-CD1 3.8Å; W287-Y290 HydrophobicContact CE3-CE1 4.44Å; W287-Y290 HydrophobicContact CE3-CG 4.42Å; W287-Y290 AromaticContact CZ3-CD1 3.71Å; W287-Y290 HydrophobicContact CZ3-CD1 3.71Å; W287-Y290 AromaticContact CZ3-CE1 3.92Å; W287-Y290 HydrophobicContact CZ3-CE1 3.92Å; W287-Y290 HydrophobicContact CZ3-CG 4.45Å; W287-Y290 PolarHBondContact O-N 3.39Å; W287-F291 HydrophobicContact CB-CD2 4.17Å; W287-F291 HydrophobicContact CB-CE2 4.4Å; W287-F291 HydrophobicContact CD2-CD2 4.4Å; W287-F291 AromaticContact CD2-CE2 3.88Å; W287-F291 HydrophobicContact CD2-CE2 3.88Å; W287-F291 AromaticContact CE3-CD2 3.63Å; W287-F291 HydrophobicContact CE3-CD2 3.63Å; W287-F291 AromaticContact CE3-CE2 3.06Å; W287-F291 HydrophobicContact CE3-CE2 3.06Å; W287-F291 AromaticContact CE3-CZ 3.86Å; W287-F291 HydrophobicContact CE3-CZ 3.86Å; W287-F291 HydrophobicContact CG-CE2 4.47Å; W287-F291 HydrophobicContact CZ3-CD2 4.38Å; W287-F291 AromaticContact CZ3-CE2 3.53Å; W287-F291 HydrophobicContact CZ3-CE2 3.53Å; W287-F291 AromaticContact CZ3-CZ 3.84Å; W287-F291 HydrophobicContact CZ3-CZ 3.84Å; W287-F291 WeakPolarHBondContact O-CD2 3.5Å; W287-F291 PolarHBondContact O-N 2.9Å; W287-P319 HydrophobicContact CE3-CG 4.2Å; W287-P319 HydrophobicContact CH2-CB 3.55Å; W287-P319 HydrophobicContact CH2-CG 3.9Å; W287-P319 HydrophobicContact CZ2-CB 3.96Å; W287-P319 HydrophobicContact CZ3-CB 3.93Å; W287-P319 HydrophobicContact CZ3-CG 3.72Å; W287-N322 PolarHBondContact NE1-OD1 2.98Å; W287-N322 VanDerWaalsContact NE1-OD1 3.16Å
288	S	97	Very high	95.8	Very high	20 Å²	20	37.3 Å²	37.3	14%	0.14	20%	0.202	C	C	.	.	H	α-helix	trans	-59.3	-50.8	-178.5	-47.4	0	0	0	0	112.3	Y219 I284 Y290 F291 L292	Y219-S288 WeakPolarHBondContact OH-CA 3.45Å; Y219-S288 VanDerWaalsContact OH-CB 3.26Å; Y219-S288 WeakPolarHBondContact OH-CB 3.47Å; Y219-S288 PolarHBondContact OH-OG 3.03Å; I284-S288 WeakPolarHBondContact CG2-OG 3.36Å; I284-S288 VanDerWaalsContact O-CB 3.25Å; I284-S288 WeakPolarHBondContact O-CB 3.21Å; I284-S288 PolarHBondContact O-N 3.01Å; I284-S288 PolarHBondContact O-OG 2.94Å; S288-Y290 VanDerWaalsContact C-N 3.26Å; S288-Y290 PolarHBondContact O-N 3.27Å; S288-F291 PolarHBondContact O-N 2.9Å; S288-L292 VanDerWaalsContact O-CB 3.23Å; S288-L292 WeakPolarHBondContact O-CB 3.29Å; S288-L292 WeakPolarHBondContact O-CG 3.33Å; S288-L292 PolarHBondContact O-N 3.38Å
289	P	97	Very high	95.7	Very high	49 Å²	49	38.9 Å²	38.9	32%	0.318	21%	0.206	S	C	.	.	H	α-helix	trans	-63.9	-35.9	-178.2	-19	33	0	0	0	111.8	C285 F293 I315 L318	C285-P289 VanDerWaalsContact O-CD 3.27Å; C285-P289 WeakPolarHBondContact O-CD 3.28Å; P289-F293 WeakPolarHBondContact O-CB 3.36Å; P289-F293 PolarHBondContact O-N 3.33Å; P289-I315 HydrophobicContact CB-CG1 4.43Å; P289-L318 HydrophobicContact CB-CD1 3.63Å; P289-L318 HydrophobicContact CG-CD1 3.76Å
290	Y	96.2	Very high	95.5	Very high	60 Å²	60	45.5 Å²	45.5	24%	0.235	24%	0.241	C	C	.	.	H	α-helix	trans	-61.7	-57.6	176.2	177.4	-94.9	0	0	0	112.5	W287 S288 L292 F293 D294 I315 P319	W287-Y290 AromaticContact CE3-CD1 3.8Å; W287-Y290 HydrophobicContact CE3-CD1 3.8Å; W287-Y290 HydrophobicContact CE3-CE1 4.44Å; W287-Y290 HydrophobicContact CE3-CG 4.42Å; W287-Y290 AromaticContact CZ3-CD1 3.71Å; W287-Y290 HydrophobicContact CZ3-CD1 3.71Å; W287-Y290 AromaticContact CZ3-CE1 3.92Å; W287-Y290 HydrophobicContact CZ3-CE1 3.92Å; W287-Y290 HydrophobicContact CZ3-CG 4.45Å; W287-Y290 PolarHBondContact O-N 3.39Å; S288-Y290 VanDerWaalsContact C-N 3.26Å; S288-Y290 PolarHBondContact O-N 3.27Å; Y290-L292 PolarHBondContact O-N 2.96Å; Y290-F293 PolarHBondContact O-N 3.4Å; Y290-D294 VanDerWaalsContact O-CB 3.32Å; Y290-D294 WeakPolarHBondContact O-CB 3.13Å; Y290-D294 PolarHBondContact O-N 2.99Å; Y290-I315 HydrophobicContact CD2-CG2 4.27Å; Y290-P319 HydrophobicContact CD1-CG 4.29Å; Y290-P319 HydrophobicContact CD2-CG 3.76Å; Y290-P319 HydrophobicContact CE2-CG 4.16Å; Y290-P319 HydrophobicContact CG-CG 3.84Å
291	F	96.4	Very high	95.5	Very high	3 Å²	3	50.6 Å²	50.6	1%	0.013	27%	0.268	C	S	.	.	H	α-helix	trans	-71.5	-31.2	-176.6	-79.2	-66.1	0	0	0	113.5	A215 V218 Y219 W287 S288 I295	A215-F291 HydrophobicContact CB-CD1 3.65Å; A215-F291 HydrophobicContact CB-CE1 4.07Å; V218-F291 HydrophobicContact CB-CE1 4.5Å; V218-F291 HydrophobicContact CB-CE2 4.37Å; V218-F291 HydrophobicContact CB-CZ 3.75Å; V218-F291 HydrophobicContact CG1-CE2 3.89Å; V218-F291 HydrophobicContact CG1-CZ 3.54Å; Y219-F291 VanDerWaalsContact CB-CE2 3.4Å; Y219-F291 HydrophobicContact CD1-CB 3.7Å; Y219-F291 AromaticContact CD1-CD2 4Å; Y219-F291 HydrophobicContact CD1-CD2 4Å; Y219-F291 HydrophobicContact CD1-CG 4.04Å; Y219-F291 AromaticContact CD2-CD2 3.87Å; Y219-F291 HydrophobicContact CD2-CD2 3.87Å; Y219-F291 HydrophobicContact CD2-CE2 4.44Å; Y219-F291 HydrophobicContact CE1-CB 4.24Å; Y219-F291 HydrophobicContact CG-CB 4.06Å; Y219-F291 AromaticContact CG-CD2 3.42Å; Y219-F291 HydrophobicContact CG-CD2 3.42Å; Y219-F291 VanDerWaalsContact CG-CD2 3.42Å; Y219-F291 HydrophobicContact CG-CE2 4.07Å; Y219-F291 AromaticContact CG-CG 3.91Å; Y219-F291 HydrophobicContact CG-CG 3.91Å; W287-F291 HydrophobicContact CB-CD2 4.17Å; W287-F291 HydrophobicContact CB-CE2 4.4Å; W287-F291 HydrophobicContact CD2-CD2 4.4Å; W287-F291 AromaticContact CD2-CE2 3.88Å; W287-F291 HydrophobicContact CD2-CE2 3.88Å; W287-F291 AromaticContact CE3-CD2 3.63Å; W287-F291 HydrophobicContact CE3-CD2 3.63Å; W287-F291 AromaticContact CE3-CE2 3.06Å; W287-F291 HydrophobicContact CE3-CE2 3.06Å; W287-F291 AromaticContact CE3-CZ 3.86Å; W287-F291 HydrophobicContact CE3-CZ 3.86Å; W287-F291 HydrophobicContact CG-CE2 4.47Å; W287-F291 HydrophobicContact CZ3-CD2 4.38Å; W287-F291 AromaticContact CZ3-CE2 3.53Å; W287-F291 HydrophobicContact CZ3-CE2 3.53Å; W287-F291 AromaticContact CZ3-CZ 3.84Å; W287-F291 HydrophobicContact CZ3-CZ 3.84Å; W287-F291 WeakPolarHBondContact O-CD2 3.5Å; W287-F291 PolarHBondContact O-N 2.9Å; S288-F291 PolarHBondContact O-N 2.9Å; F291-I295 WeakPolarHBondContact O-CB 3.39Å; F291-I295 VanDerWaalsContact O-CG1 3.27Å; F291-I295 WeakPolarHBondContact O-CG1 3.33Å; F291-I295 PolarHBondContact O-N 3.34Å
292	L	96.6	Very high	95.2	Very high	89 Å²	89	48 Å²	48	47%	0.466	26%	0.255	S	S	.	.	H	α-helix	trans	-68	-44.6	174.2	-68.6	174.1	0	0	0	111.1	F220 S288 Y290 L296	F220-L292 HydrophobicContact CZ-CD2 4.48Å; S288-L292 VanDerWaalsContact O-CB 3.23Å; S288-L292 WeakPolarHBondContact O-CB 3.29Å; S288-L292 WeakPolarHBondContact O-CG 3.33Å; S288-L292 PolarHBondContact O-N 3.38Å; Y290-L292 PolarHBondContact O-N 2.96Å; L292-L296 VanDerWaalsContact O-CG 3.23Å; L292-L296 WeakPolarHBondContact O-CG 3.38Å; L292-L296 PolarHBondContact O-N 3.09Å
293	F	95.9	Very high	95	Very high	35 Å²	35	51.6 Å²	51.6	15%	0.154	28%	0.277	C	S	.	.	H	α-helix	trans	-61.5	-49.3	175.3	-176.3	-85.9	0	0	0	111.1	P289 Y290 I295 L296 D297 L302 R308 A311 I315	P289-F293 WeakPolarHBondContact O-CB 3.36Å; P289-F293 PolarHBondContact O-N 3.33Å; Y290-F293 PolarHBondContact O-N 3.4Å; F293-I295 VanDerWaalsContact C-N 3.34Å; F293-I295 PolarHBondContact O-N 2.98Å; F293-L296 PolarHBondContact O-N 2.8Å; F293-D297 HydrophobicContact CE1-CB 4.32Å; F293-D297 VanDerWaalsContact O-CB 3.28Å; F293-D297 WeakPolarHBondContact O-CB 3.38Å; F293-D297 PolarHBondContact O-N 2.98Å; F293-L302 HydrophobicContact CD2-CD1 3.8Å; F293-L302 HydrophobicContact CE1-CD1 4.35Å; F293-L302 HydrophobicContact CE2-CD1 3.55Å; F293-L302 HydrophobicContact CG-CD1 4.32Å; F293-L302 HydrophobicContact CZ-CD1 3.84Å; F293-R308 HydrophobicContact CE2-CG 4.37Å; F293-R308 HydrophobicContact CZ-CG 3.99Å; F293-A311 HydrophobicContact CD2-CB 4.49Å; F293-A311 HydrophobicContact CE2-CB 3.96Å; F293-I315 HydrophobicContact CB-CD1 3.85Å; F293-I315 HydrophobicContact CB-CG2 4.13Å; F293-I315 HydrophobicContact CD2-CD1 3.61Å; F293-I315 HydrophobicContact CE2-CD1 4.4Å; F293-I315 HydrophobicContact CG-CD1 3.84Å; F293-I315 HydrophobicContact CG-CG2 4.5Å
294	D	94.4	Very high	94.5	Very high	21 Å²	21	59 Å²	59	11%	0.112	32%	0.316	C	S	.	.	H	α-helix	trans	-56.7	-44.6	179.3	179.7	73.3	0	0	0	112.1	M211 Y290 D297 N298	M211-D294 VanDerWaalsContact CE-OD1 3.31Å; M211-D294 WeakPolarHBondContact CE-OD1 3.14Å; Y290-D294 VanDerWaalsContact O-CB 3.32Å; Y290-D294 WeakPolarHBondContact O-CB 3.13Å; Y290-D294 PolarHBondContact O-N 2.99Å; D294-D297 PolarHBondContact O-N 3.42Å; D294-N298 VanDerWaalsContact O-CB 3.23Å; D294-N298 WeakPolarHBondContact O-CB 3.24Å; D294-N298 PolarHBondContact O-N 3.23Å; D294-N298 PolarHBondContact O-ND2 3.37Å; D294-N298 PolarHBondContact OD1-ND2 3.32Å; D294-N298 PolarHBondContact OD2-ND2 3.36Å
295	I	95.7	Very high	94.2	Very high	31 Å²	31	59.6 Å²	59.6	16%	0.159	32%	0.322	C	S	.	.	H	α-helix	trans	-65	-47.2	176.6	-71.7	-68.1	0	0	0	111.7	T212 A215 F220 F291 F293 D297 N298 F299	T212-I295 HydrophobicContact CG2-CD1 4.47Å; A215-I295 HydrophobicContact CB-CD1 3.87Å; A215-I295 HydrophobicContact CB-CG1 4.14Å; F220-I295 HydrophobicContact CE2-CG1 4.31Å; F291-I295 WeakPolarHBondContact O-CB 3.39Å; F291-I295 VanDerWaalsContact O-CG1 3.27Å; F291-I295 WeakPolarHBondContact O-CG1 3.33Å; F291-I295 PolarHBondContact O-N 3.34Å; F293-I295 VanDerWaalsContact C-N 3.34Å; F293-I295 PolarHBondContact O-N 2.98Å; I295-D297 VanDerWaalsContact C-N 3.27Å; I295-D297 PolarHBondContact O-N 3.02Å; I295-N298 PolarHBondContact O-N 3.1Å; I295-F299 HydrophobicContact CG2-CD2 3.95Å; I295-F299 HydrophobicContact CG2-CE2 4.11Å; I295-F299 VanDerWaalsContact O-CD2 3.24Å; I295-F299 WeakPolarHBondContact O-CD2 3.22Å; I295-F299 PolarHBondContact O-N 2.88Å
296	L	95.7	Very high	93.7	Very high	73 Å²	73	61 Å²	61	38%	0.382	32%	0.32	S	S	.	.	H	α-helix	trans	-61.9	-38.2	179.3	-67.4	172	0	0	0	111.8	L292 F293 N300 L301 L302	L292-L296 VanDerWaalsContact O-CG 3.23Å; L292-L296 WeakPolarHBondContact O-CG 3.38Å; L292-L296 PolarHBondContact O-N 3.09Å; F293-L296 PolarHBondContact O-N 2.8Å; L296-N300 PolarHBondContact O-N 3.39Å; L296-L301 HydrophobicContact CD2-CB 4.26Å; L296-L301 HydrophobicContact CD2-CD1 3.88Å; L296-L301 WeakPolarHBondContact O-CB 3.39Å; L296-L301 PolarHBondContact O-N 2.91Å; L296-L302 HydrophobicContact CB-CD1 4.06Å; L296-L302 HydrophobicContact CB-CD2 3.91Å; L296-L302 HydrophobicContact CB-CG 3.78Å; L296-L302 HydrophobicContact CD1-CD2 4.19Å
297	D	92.7	Very high	93.3	Very high	42 Å²	42	68 Å²	68	23%	0.225	35%	0.352	C	S	.	.	H	α-helix	trans	-65.2	-48.6	175.8	-157.2	71.2	0	0	0	111.4	F293 D294 I295 F299 N300 L302 R308	F293-D297 HydrophobicContact CE1-CB 4.32Å; F293-D297 VanDerWaalsContact O-CB 3.28Å; F293-D297 WeakPolarHBondContact O-CB 3.38Å; F293-D297 PolarHBondContact O-N 2.98Å; D294-D297 PolarHBondContact O-N 3.42Å; I295-D297 VanDerWaalsContact C-N 3.27Å; I295-D297 PolarHBondContact O-N 3.02Å; D297-F299 PolarHBondContact O-N 3.25Å; D297-N300 PolarHBondContact O-N 3.46Å; D297-L302 HydrophobicContact CB-CD1 4.05Å; D297-R308 IonicContact OD1-CZ 3.93Å; D297-R308 IonicContact OD1-NE 3.24Å; D297-R308 PolarHBondContact OD1-NE 3.04Å; D297-R308 IonicContact OD1-NH2 2.87Å; D297-R308 PolarHBondContact OD1-NH2 3.08Å; D297-R308 IonicContact OD2-NH2 3.15Å; D297-R308 PolarHBondContact OD2-NH2 3.32Å
298	N	92.5	Very high	92.9	Very high	10 Å²	10	70.1 Å²	70.1	5%	0.053	36%	0.36	C	S	.	.	H	α-helix	trans	-63.3	-23.5	-178.8	-76.6	-39	0	0	0	114.3	W207 T208 M211 D294 I295	W207-N298 PolarHBondContact NE1-OD1 3.38Å; T208-N298 HydrophobicContact CG2-CB 4.41Å; T208-N298 WeakPolarHBondContact CG2-O 3.47Å; T208-N298 PolarHBondContact OG1-O 2.96Å; M211-N298 VanDerWaalsContact CB-ND2 3.32Å; M211-N298 WeakPolarHBondContact CB-ND2 3.35Å; D294-N298 VanDerWaalsContact O-CB 3.23Å; D294-N298 WeakPolarHBondContact O-CB 3.24Å; D294-N298 PolarHBondContact O-N 3.23Å; D294-N298 PolarHBondContact O-ND2 3.37Å; D294-N298 PolarHBondContact OD1-ND2 3.32Å; D294-N298 PolarHBondContact OD2-ND2 3.36Å; I295-N298 PolarHBondContact O-N 3.1Å
299	F	94.3	Very high	92.4	Very high	107 Å²	107	72.5 Å²	72.5	47%	0.469	37%	0.368	S	S	.	.	T	Hydrogen-bonded Turn	trans	-99.1	10.8	174.2	-73.1	-73.7	0	0	0	113.2	T208 I295 D297 L301	T208-F299 HydrophobicContact CG2-CD1 4.16Å; T208-F299 HydrophobicContact CG2-CE1 3.82Å; T208-F299 HydrophobicContact CG2-CE2 4.49Å; T208-F299 HydrophobicContact CG2-CZ 3.99Å; I295-F299 HydrophobicContact CG2-CD2 3.95Å; I295-F299 HydrophobicContact CG2-CE2 4.11Å; I295-F299 VanDerWaalsContact O-CD2 3.24Å; I295-F299 WeakPolarHBondContact O-CD2 3.22Å; I295-F299 PolarHBondContact O-N 2.88Å; D297-F299 PolarHBondContact O-N 3.25Å; F299-L301 HydrophobicContact CB-CD1 4.13Å; F299-L301 HydrophobicContact CB-CG 3.99Å; F299-L301 PolarHBondContact O-N 2.92Å
300	N	90.9	Very high	91.9	Very high	140 Å²	140	73.8 Å²	73.8	75%	0.749	37%	0.367	S	S	*	.	T	Hydrogen-bonded Turn	trans	54.1	35.7	-179.2	-58.3	-52.6	0	0	0	113.3	L296 D297	L296-N300 PolarHBondContact O-N 3.39Å; D297-N300 PolarHBondContact O-N 3.46Å
301	L	93.6	Very high	91.7	Very high	119 Å²	119	72.6 Å²	72.6	62%	0.623	37%	0.37	S	S	*	.			trans	-89.6	-8.6	178.4	-61.4	177.6	0	0	0	112.6	L296 F299	L296-L301 HydrophobicContact CD2-CB 4.26Å; L296-L301 HydrophobicContact CD2-CD1 3.88Å; L296-L301 WeakPolarHBondContact O-CB 3.39Å; L296-L301 PolarHBondContact O-N 2.91Å; F299-L301 HydrophobicContact CB-CD1 4.13Å; F299-L301 HydrophobicContact CB-CG 3.99Å; F299-L301 PolarHBondContact O-N 2.92Å
302	L	91.8	Very high	91.4	Very high	41 Å²	41	73.5 Å²	73.5	22%	0.215	38%	0.377	C	S	.	.	S	Bend	trans	-99.1	132.8	177.4	-60.6	178.2	0	0	0	110.4	F293 L296 D297 R308	F293-L302 HydrophobicContact CD2-CD1 3.8Å; F293-L302 HydrophobicContact CE1-CD1 4.35Å; F293-L302 HydrophobicContact CE2-CD1 3.55Å; F293-L302 HydrophobicContact CG-CD1 4.32Å; F293-L302 HydrophobicContact CZ-CD1 3.84Å; L296-L302 HydrophobicContact CB-CD1 4.06Å; L296-L302 HydrophobicContact CB-CD2 3.91Å; L296-L302 HydrophobicContact CB-CG 3.78Å; L296-L302 HydrophobicContact CD1-CD2 4.19Å; D297-L302 HydrophobicContact CB-CD1 4.05Å; L302-R308 HydrophobicContact CB-CG 4.47Å
303	P	90.6	Very high	91	Very high	86 Å²	86	70 Å²	70	56%	0.558	36%	0.358	S	S	*	.			trans	-71.7	150.7	178.1	31.5	-36	0	0	0	111.8	T305 R308	P303-T305 VanDerWaalsContact C-N 3.31Å; P303-T305 HydrophobicContact CB-CG2 4Å; P303-T305 HydrophobicContact CG-CG2 4.01Å; P303-T305 PolarHBondContact O-N 2.93Å; P303-R308 WeakPolarHBondContact O-CD 3.43Å
304	D	86.8	Confident	90.7	Very high	155 Å²	155	73.6 Å²	73.6	83%	0.829	38%	0.378	S	S	*	.	S	Bend	trans	-73.2	80.3	173.8	-67.9	-51.5	0	0	0	111	R308	D304-R308 IonicContact OD1-CZ 3.38Å; D304-R308 IonicContact OD1-NH1 2.8Å; D304-R308 PolarHBondContact OD1-NH1 3.12Å
305	T	90.2	Very high	90.7	Very high	60 Å²	60	73.8 Å²	73.8	37%	0.368	38%	0.379	S	S	.	.			trans	-122.3	159	179.9	65.1	0	0	0	0	111.9	P303 E307 R308 F309	P303-T305 VanDerWaalsContact C-N 3.31Å; P303-T305 HydrophobicContact CB-CG2 4Å; P303-T305 HydrophobicContact CG-CG2 4.01Å; P303-T305 PolarHBondContact O-N 2.93Å; T305-E307 PolarHBondContact O-N 2.89Å; T305-R308 WeakPolarHBondContact O-CB 3.32Å; T305-R308 PolarHBondContact O-N 2.75Å; T305-R308 VanDerWaalsContact O-N 3.16Å; T305-R308 PolarHBondContact OG1-N 3Å; T305-F309 PolarHBondContact O-N 3.01Å
306	Q	85.1	Confident	90.5	Very high	120 Å²	120	77.2 Å²	77.2	56%	0.561	39%	0.394	S	S	*	.	H	α-helix	trans	-57.5	-37	170.4	-66.7	-176	-8.4	0	0	111.1	R308 F309 Y310	Q306-R308 VanDerWaalsContact C-N 3.34Å; Q306-R308 PolarHBondContact O-N 3.45Å; Q306-F309 WeakPolarHBondContact O-CA 3.5Å; Q306-F309 WeakPolarHBondContact O-CB 2.96Å; Q306-F309 PolarHBondContact O-N 3.44Å; Q306-Y310 VanDerWaalsContact C-CD2 3.5Å; Q306-Y310 HydrophobicContact CB-CD2 4.45Å; Q306-Y310 HydrophobicContact CB-CE2 3.95Å; Q306-Y310 WeakPolarHBondContact O-CD2 3.5Å; Q306-Y310 PolarHBondContact O-N 3.49Å
307	E	88.3	Confident	90.4	Very high	154 Å²	154	74.6 Å²	74.6	72%	0.72	38%	0.381	S	S	*	.	H	α-helix	trans	-56.5	-43	175.1	-62.7	-178.6	174.4	0	0	113	T305 F309 Y310 A311	T305-E307 PolarHBondContact O-N 2.89Å; E307-F309 VanDerWaalsContact C-N 3.29Å; E307-F309 PolarHBondContact O-N 2.96Å; E307-Y310 PolarHBondContact O-N 3.22Å; E307-A311 WeakPolarHBondContact O-CB 3.04Å; E307-A311 PolarHBondContact O-N 2.54Å
308	R	88.9	Confident	90.6	Very high	57 Å²	57	74.2 Å²	74.2	22%	0.215	38%	0.379	C	S	.	.	H	α-helix	trans	-59.7	-41.5	174.1	177.5	-178.9	167.4	-154.6	-7.2	111.3	F293 D297 L302 P303 D304 T305 Q306 A311 S312	F293-R308 HydrophobicContact CE2-CG 4.37Å; F293-R308 HydrophobicContact CZ-CG 3.99Å; D297-R308 IonicContact OD1-CZ 3.93Å; D297-R308 IonicContact OD1-NE 3.24Å; D297-R308 PolarHBondContact OD1-NE 3.04Å; D297-R308 IonicContact OD1-NH2 2.87Å; D297-R308 PolarHBondContact OD1-NH2 3.08Å; D297-R308 IonicContact OD2-NH2 3.15Å; D297-R308 PolarHBondContact OD2-NH2 3.32Å; L302-R308 HydrophobicContact CB-CG 4.47Å; P303-R308 WeakPolarHBondContact O-CD 3.43Å; D304-R308 IonicContact OD1-CZ 3.38Å; D304-R308 IonicContact OD1-NH1 2.8Å; D304-R308 PolarHBondContact OD1-NH1 3.12Å; T305-R308 WeakPolarHBondContact O-CB 3.32Å; T305-R308 PolarHBondContact O-N 2.75Å; T305-R308 VanDerWaalsContact O-N 3.16Å; T305-R308 PolarHBondContact OG1-N 3Å; Q306-R308 VanDerWaalsContact C-N 3.34Å; Q306-R308 PolarHBondContact O-N 3.45Å; R308-A311 PolarHBondContact O-N 3.17Å; R308-S312 WeakPolarHBondContact O-CB 3.03Å; R308-S312 PolarHBondContact O-N 3.42Å
309	F	86.9	Confident	90.6	Very high	70 Å²	70	74.9 Å²	74.9	31%	0.307	38%	0.383	S	S	.	.	H	α-helix	trans	-64.3	-45.3	176.6	-178.4	-96.3	0	0	0	112.1	F44 Y45 T305 Q306 E307 A311 S312 V313	F44-F309 HydrophobicContact CE1-CD1 4.4Å; F44-F309 HydrophobicContact CE1-CE1 4.3Å; Y45-F309 HydrophobicContact CD2-CZ 4.21Å; Y45-F309 HydrophobicContact CE2-CZ 4.36Å; T305-F309 PolarHBondContact O-N 3.01Å; Q306-F309 WeakPolarHBondContact O-CA 3.5Å; Q306-F309 WeakPolarHBondContact O-CB 2.96Å; Q306-F309 PolarHBondContact O-N 3.44Å; E307-F309 VanDerWaalsContact C-N 3.29Å; E307-F309 PolarHBondContact O-N 2.96Å; F309-A311 PolarHBondContact O-N 2.85Å; F309-S312 PolarHBondContact O-N 2.95Å; F309-S312 PolarHBondContact O-OG 3.24Å; F309-V313 HydrophobicContact CD1-CG2 4.48Å; F309-V313 HydrophobicContact CE1-CG2 4.12Å; F309-V313 HydrophobicContact CE2-CG2 4.49Å; F309-V313 HydrophobicContact CZ-CG2 4.13Å; F309-V313 WeakPolarHBondContact O-CG2 3.28Å; F309-V313 PolarHBondContact O-N 2.81Å; F309-V313 VanDerWaalsContact O-N 3.15Å
310	Y	87.4	Confident	90.7	Very high	77 Å²	77	70.3 Å²	70.3	30%	0.302	37%	0.365	S	S	.	.	H	α-helix	trans	-60.5	-45.2	174.9	-66.8	-76.9	0	0	0	112	F44 F48 Q306 E307 V313 I314	F44-Y310 AromaticContact CE2-CE1 3.54Å; F44-Y310 HydrophobicContact CE2-CE1 3.54Å; F44-Y310 AromaticContact CE2-CZ 3.52Å; F44-Y310 WeakPolarHBondContact CE2-OH 3.38Å; F44-Y310 HydrophobicContact CZ-CD1 4.21Å; F44-Y310 AromaticContact CZ-CE1 3.29Å; F44-Y310 HydrophobicContact CZ-CE1 3.29Å; F44-Y310 HydrophobicContact CZ-CE2 4.21Å; F44-Y310 AromaticContact CZ-CZ 3.27Å; F44-Y310 WeakPolarHBondContact CZ-OH 3.33Å; F48-Y310 HydrophobicContact CD1-CD1 4.41Å; F48-Y310 AromaticContact CE1-CD1 3.56Å; F48-Y310 HydrophobicContact CE1-CD1 3.56Å; F48-Y310 AromaticContact CE1-CE1 3.74Å; F48-Y310 HydrophobicContact CE1-CE1 3.74Å; F48-Y310 HydrophobicContact CE2-CD1 4.38Å; F48-Y310 AromaticContact CE2-CE1 3.71Å; F48-Y310 HydrophobicContact CE2-CE1 3.71Å; F48-Y310 AromaticContact CZ-CD1 3.58Å; F48-Y310 HydrophobicContact CZ-CD1 3.58Å; F48-Y310 AromaticContact CZ-CE1 3.24Å; F48-Y310 HydrophobicContact CZ-CE1 3.24Å; Q306-Y310 VanDerWaalsContact C-CD2 3.5Å; Q306-Y310 HydrophobicContact CB-CD2 4.45Å; Q306-Y310 HydrophobicContact CB-CE2 3.95Å; Q306-Y310 WeakPolarHBondContact O-CD2 3.5Å; Q306-Y310 PolarHBondContact O-N 3.49Å; E307-Y310 PolarHBondContact O-N 3.22Å; Y310-V313 PolarHBondContact O-N 3.28Å; Y310-I314 WeakPolarHBondContact O-CG1 3.5Å; Y310-I314 PolarHBondContact O-N 3.32Å; Y310-I314 VanDerWaalsContact O-N 3.17Å
311	A	91	Very high	90.9	Very high	34 Å²	34	67 Å²	67	28%	0.281	35%	0.347	S	S	.	.	H	α-helix	trans	-60.9	-46.5	179.2	0	0	0	0	0	111.1	F293 E307 R308 F309 V313 I314 I315	F293-A311 HydrophobicContact CD2-CB 4.49Å; F293-A311 HydrophobicContact CE2-CB 3.96Å; E307-A311 WeakPolarHBondContact O-CB 3.04Å; E307-A311 PolarHBondContact O-N 2.54Å; R308-A311 PolarHBondContact O-N 3.17Å; F309-A311 PolarHBondContact O-N 2.85Å; A311-V313 VanDerWaalsContact C-N 3.32Å; A311-V313 PolarHBondContact O-N 2.96Å; A311-I314 PolarHBondContact O-N 3.03Å; A311-I315 HydrophobicContact CB-CD1 4.23Å; A311-I315 WeakPolarHBondContact O-CB 3.34Å; A311-I315 WeakPolarHBondContact O-CD1 3.48Å; A311-I315 WeakPolarHBondContact O-CG1 3.21Å; A311-I315 PolarHBondContact O-N 3.38Å
312	S	90	Very high	91.1	Very high	23 Å²	23	61.5 Å²	61.5	16%	0.161	32%	0.319	C	S	.	.	H	α-helix	trans	-61.4	-39.8	-179.8	79.9	0	0	0	0	112.1	R308 F309 Q316	R308-S312 WeakPolarHBondContact O-CB 3.03Å; R308-S312 PolarHBondContact O-N 3.42Å; F309-S312 PolarHBondContact O-N 2.95Å; F309-S312 PolarHBondContact O-OG 3.24Å; S312-Q316 VanDerWaalsContact O-CB 3.31Å; S312-Q316 WeakPolarHBondContact O-CB 3.29Å; S312-Q316 WeakPolarHBondContact O-CG 3.46Å; S312-Q316 PolarHBondContact O-N 2.99Å; S312-Q316 PolarHBondContact O-NE2 3.19Å
313	V	87.7	Confident	91.3	Very high	14 Å²	14	59.7 Å²	59.7	9%	0.085	31%	0.31	C	S	.	.	H	α-helix	trans	-64.9	-45.6	179.2	169	0	0	0	0	111.5	Q52 F309 Y310 A311 N317	Q52-V313 HydrophobicContact CB-CG1 4.49Å; Q52-V313 HydrophobicContact CG-CG1 4.4Å; F309-V313 HydrophobicContact CD1-CG2 4.48Å; F309-V313 HydrophobicContact CE1-CG2 4.12Å; F309-V313 HydrophobicContact CE2-CG2 4.49Å; F309-V313 HydrophobicContact CZ-CG2 4.13Å; F309-V313 WeakPolarHBondContact O-CG2 3.28Å; F309-V313 PolarHBondContact O-N 2.81Å; F309-V313 VanDerWaalsContact O-N 3.15Å; Y310-V313 PolarHBondContact O-N 3.28Å; A311-V313 VanDerWaalsContact C-N 3.32Å; A311-V313 PolarHBondContact O-N 2.96Å; V313-N317 PolarHBondContact O-ND2 3.34Å; V313-N317 VanDerWaalsContact O-ND2 3.17Å
314	I	91.2	Very high	91.5	Very high	112 Å²	112	56 Å²	56	57%	0.574	29%	0.286	S	S	*	.	H	α-helix	trans	-67.9	-47.1	179.4	-65.4	168.9	0	0	0	110.3	Y310 A311 Q316 N317	Y310-I314 WeakPolarHBondContact O-CG1 3.5Å; Y310-I314 PolarHBondContact O-N 3.32Å; Y310-I314 VanDerWaalsContact O-N 3.17Å; A311-I314 PolarHBondContact O-N 3.03Å; I314-Q316 VanDerWaalsContact C-N 3.33Å; I314-Q316 PolarHBondContact O-N 3.43Å; I314-N317 PolarHBondContact O-N 2.98Å
315	I	94.2	Very high	92	Very high	25 Å²	25	51 Å²	51	13%	0.128	26%	0.259	C	S	.	.	H	α-helix	trans	-64.6	-36.3	-175.2	-72.2	170.5	0	0	0	111.7	P289 Y290 F293 A311 N317 L318	P289-I315 HydrophobicContact CB-CG1 4.43Å; Y290-I315 HydrophobicContact CD2-CG2 4.27Å; F293-I315 HydrophobicContact CB-CD1 3.85Å; F293-I315 HydrophobicContact CB-CG2 4.13Å; F293-I315 HydrophobicContact CD2-CD1 3.61Å; F293-I315 HydrophobicContact CE2-CD1 4.4Å; F293-I315 HydrophobicContact CG-CD1 3.84Å; F293-I315 HydrophobicContact CG-CG2 4.5Å; A311-I315 HydrophobicContact CB-CD1 4.23Å; A311-I315 WeakPolarHBondContact O-CB 3.34Å; A311-I315 WeakPolarHBondContact O-CD1 3.48Å; A311-I315 WeakPolarHBondContact O-CG1 3.21Å; A311-I315 PolarHBondContact O-N 3.38Å; I315-N317 PolarHBondContact O-N 3.2Å; I315-N317 VanDerWaalsContact O-N 3.17Å; I315-L318 WeakPolarHBondContact O-CB 3.39Å; I315-L318 WeakPolarHBondContact O-CG 3.48Å; I315-L318 PolarHBondContact O-N 2.95Å; I315-L318 VanDerWaalsContact O-N 3.09Å
316	Q	91.5	Very high	92.2	Very high	102 Å²	102	48.6 Å²	48.6	48%	0.477	24%	0.244	S	C	.	.	T	Hydrogen-bonded Turn	trans	-62.7	-19.9	177.6	-80.2	178.3	95.4	0	0	114.1	S312 I314	S312-Q316 VanDerWaalsContact O-CB 3.31Å; S312-Q316 WeakPolarHBondContact O-CB 3.29Å; S312-Q316 WeakPolarHBondContact O-CG 3.46Å; S312-Q316 PolarHBondContact O-N 2.99Å; S312-Q316 PolarHBondContact O-NE2 3.19Å; I314-Q316 VanDerWaalsContact C-N 3.33Å; I314-Q316 PolarHBondContact O-N 3.43Å
317	N	93.2	Very high	92.7	Very high	19 Å²	19	43.2 Å²	43.2	10%	0.102	22%	0.219	C	C	.	.	T	Hydrogen-bonded Turn	trans	-84.6	-15.4	177	-63.3	-42.4	0	0	0	113.2	L59 V313 I314 I315 A320 L321	L59-N317 HydrophobicContact CD1-CB 4.31Å; V313-N317 PolarHBondContact O-ND2 3.34Å; V313-N317 VanDerWaalsContact O-ND2 3.17Å; I314-N317 PolarHBondContact O-N 2.98Å; I315-N317 PolarHBondContact O-N 3.2Å; I315-N317 VanDerWaalsContact O-N 3.17Å; N317-A320 PolarHBondContact O-N 3.37Å; N317-L321 PolarHBondContact O-N 3.08Å
318	L	96	Very high	93	Very high	33 Å²	33	40.6 Å²	40.6	17%	0.173	21%	0.209	C	C	.	.	H	α-helix	trans	-64.7	-38.5	-175.9	-60.9	175.5	0	0	0	114.1	C286 P289 I315 A320 L321 N322	C286-L318 HydrophobicContact CB-CB 4.48Å; C286-L318 WeakPolarHBondContact CB-O 3.33Å; C286-L318 WeakPolarHBondContact O-CB 3.41Å; P289-L318 HydrophobicContact CB-CD1 3.63Å; P289-L318 HydrophobicContact CG-CD1 3.76Å; I315-L318 WeakPolarHBondContact O-CB 3.39Å; I315-L318 WeakPolarHBondContact O-CG 3.48Å; I315-L318 PolarHBondContact O-N 2.95Å; I315-L318 VanDerWaalsContact O-N 3.09Å; L318-A320 VanDerWaalsContact C-N 3.29Å; L318-A320 PolarHBondContact O-N 3.01Å; L318-L321 HydrophobicContact CD2-CD2 4.18Å; L318-L321 WeakPolarHBondContact O-CB 3.29Å; L318-L321 PolarHBondContact O-N 3.05Å; L318-L321 VanDerWaalsContact O-N 3.15Å; L318-N322 PolarHBondContact O-N 3.4Å
319	P	94.1	Very high	93.3	Very high	24 Å²	24	38.4 Å²	38.4	16%	0.156	20%	0.202	C	C	.	.	H	α-helix	trans	-55.4	-41.1	170.9	-31.4	39.3	0	0	0	113.8	W287 Y290 N322	W287-P319 HydrophobicContact CE3-CG 4.2Å; W287-P319 HydrophobicContact CH2-CB 3.55Å; W287-P319 HydrophobicContact CH2-CG 3.9Å; W287-P319 HydrophobicContact CZ2-CB 3.96Å; W287-P319 HydrophobicContact CZ3-CB 3.93Å; W287-P319 HydrophobicContact CZ3-CG 3.72Å; Y290-P319 HydrophobicContact CD1-CG 4.29Å; Y290-P319 HydrophobicContact CD2-CG 3.76Å; Y290-P319 HydrophobicContact CE2-CG 4.16Å; Y290-P319 HydrophobicContact CG-CG 3.84Å; P319-N322 WeakPolarHBondContact O-CB 3.5Å; P319-N322 PolarHBondContact O-N 2.84Å
320	A	95.2	Very high	93.5	Very high	11 Å²	11	35.8 Å²	35.8	9%	0.091	19%	0.19	C	C	.	.	H	α-helix	trans	-68.2	-39	176.3	0	0	0	0	0	111.4	L59 I102 N317 L318 N322 S323 A324	L59-A320 HydrophobicContact CB-CB 4.48Å; L59-A320 HydrophobicContact CD1-CB 3.85Å; I102-A320 HydrophobicContact CD1-CB 3.79Å; I102-A320 HydrophobicContact CG1-CB 4Å; N317-A320 PolarHBondContact O-N 3.37Å; L318-A320 VanDerWaalsContact C-N 3.29Å; L318-A320 PolarHBondContact O-N 3.01Å; A320-N322 VanDerWaalsContact C-N 3.27Å; A320-N322 PolarHBondContact O-N 2.87Å; A320-S323 PolarHBondContact O-N 3.42Å; A320-A324 PolarHBondContact O-N 2.93Å; A320-A324 VanDerWaalsContact O-N 3.13Å
321	L	96.3	Very high	93.7	Very high	70 Å²	70	35 Å²	35	37%	0.366	20%	0.195	S	C	.	.	H	α-helix	trans	-59.4	-36.2	173.7	-178.6	62.6	0	0	0	112.5	L59 N317 L318 S323 A324 I325	L59-L321 HydrophobicContact CD2-CB 4.3Å; L59-L321 HydrophobicContact CD2-CD1 4.01Å; N317-L321 PolarHBondContact O-N 3.08Å; L318-L321 HydrophobicContact CD2-CD2 4.18Å; L318-L321 WeakPolarHBondContact O-CB 3.29Å; L318-L321 PolarHBondContact O-N 3.05Å; L318-L321 VanDerWaalsContact O-N 3.15Å; L321-S323 VanDerWaalsContact C-N 3.26Å; L321-S323 PolarHBondContact O-N 3.33Å; L321-A324 PolarHBondContact O-N 3.46Å; L321-A324 VanDerWaalsContact O-N 3.16Å; L321-I325 PolarHBondContact O-N 2.92Å
322	N	96.4	Very high	93.6	Very high	4 Å²	4	37.9 Å²	37.9	2%	0.021	21%	0.209	C	C	.	.	H	α-helix	trans	-58	-38.7	176.5	-176.4	-116.2	0	0	0	112.7	F283 C286 W287 L318 P319 A320 N326	F283-N322 WeakPolarHBondContact CA-ND2 3.29Å; C286-N322 HydrophobicContact CB-CB 3.69Å; W287-N322 PolarHBondContact NE1-OD1 2.98Å; W287-N322 VanDerWaalsContact NE1-OD1 3.16Å; L318-N322 PolarHBondContact O-N 3.4Å; P319-N322 WeakPolarHBondContact O-CB 3.5Å; P319-N322 PolarHBondContact O-N 2.84Å; A320-N322 VanDerWaalsContact C-N 3.27Å; A320-N322 PolarHBondContact O-N 2.87Å; N322-N326 PolarHBondContact O-ND2 3.43Å
323	S	96	Very high	93.5	Very high	4 Å²	4	37.8 Å²	37.8	3%	0.028	21%	0.206	C	C	.	.	H	α-helix	trans	-76.6	-33.9	177.2	-59.2	0	0	0	0	112.1	N67 T97 A320 L321	N67-S323 PolarHBondContact ND2-O 2.77Å; T97-S323 WeakPolarHBondContact CG2-OG 3.32Å; A320-S323 PolarHBondContact O-N 3.42Å; L321-S323 VanDerWaalsContact C-N 3.26Å; L321-S323 PolarHBondContact O-N 3.33Å
324	A	96.2	Very high	93.1	Very high	7 Å²	7	37.8 Å²	37.8	6%	0.058	21%	0.206	C	C	.	.	H	α-helix	trans	-73.4	-30.2	-177.4	0	0	0	0	0	113.7	L59 F62 T63 A320 L321 P327	L59-A324 HydrophobicContact CD2-CB 3.94Å; F62-A324 HydrophobicContact CB-CB 4.4Å; T63-A324 WeakPolarHBondContact OG1-CA 3.46Å; T63-A324 WeakPolarHBondContact OG1-CB 3.29Å; A320-A324 PolarHBondContact O-N 2.93Å; A320-A324 VanDerWaalsContact O-N 3.13Å; L321-A324 PolarHBondContact O-N 3.46Å; L321-A324 VanDerWaalsContact O-N 3.16Å; A324-P327 WeakPolarHBondContact O-CD 3.46Å
325	I	96.4	Very high	92	Very high	52 Å²	52	35.2 Å²	35.2	27%	0.267	20%	0.198	S	C	.	.	H	α-helix	trans	-80.7	-23.3	-176	-161	169.6	0	0	0	113.4	A282 L321 L328 I329	A282-I325 HydrophobicContact CB-CG2 4.03Å; L321-I325 PolarHBondContact O-N 2.92Å; I325-L328 HydrophobicContact CG1-CD1 4.47Å; I325-L328 WeakPolarHBondContact O-CB 3.03Å; I325-L328 PolarHBondContact O-N 2.79Å; I325-I329 HydrophobicContact CG1-CD1 4.3Å; I325-I329 HydrophobicContact CG1-CG1 4.33Å; I325-I329 HydrophobicContact CG2-CD1 4.15Å; I325-I329 WeakPolarHBondContact O-CG1 3.14Å; I325-I329 PolarHBondContact O-N 3.4Å
326	N	95.1	Very high	90.1	Very high	8 Å²	8	37.9 Å²	37.9	4%	0.043	22%	0.219	C	C	.	.	H	α-helix	trans	-57	-43.2	-176.3	-72.4	-22.7	0	0	0	113.8	D94 N322 L328 I329 Y330	D94-N326 PolarHBondContact OD2-ND2 2.81Å; N322-N326 PolarHBondContact O-ND2 3.43Å; N326-L328 VanDerWaalsContact C-N 3.35Å; N326-L328 PolarHBondContact O-N 3.14Å; N326-I329 PolarHBondContact O-N 3.37Å; N326-Y330 PolarHBondContact O-N 3.43Å
327	P	95.2	Very high	88.2	Confident	7 Å²	7	37.5 Å²	37.5	5%	0.045	22%	0.219	C	C	.	.	H	α-helix	trans	-57.6	-41	170.9	-29.1	36.5	0	0	0	114.5	N67 V70 A324 Y330 C331	N67-P327 HydrophobicContact CB-CG 4.4Å; N67-P327 WeakPolarHBondContact OD1-CG 3.42Å; V70-P327 HydrophobicContact CG2-CB 3.85Å; V70-P327 HydrophobicContact CG2-CG 4.19Å; A324-P327 WeakPolarHBondContact O-CD 3.46Å; P327-Y330 CarbonylContact O-C 3.54Å; P327-Y330 PolarHBondContact O-N 2.02Å; P327-C331 WeakPolarHBondContact O-CB 3.49Å; P327-C331 PolarHBondContact O-N 2.82Å; P327-C331 PolarHBondContact O-SG 3.42Å
328	L	94.2	Very high	85.7	Confident	99 Å²	99	39.4 Å²	39.4	52%	0.518	24%	0.235	S	C	.	.	H	α-helix	trans	-63.8	-44.2	178	-61.7	175.7	0	0	0	110.7	I325 N326 Y330 C331 V332	I325-L328 HydrophobicContact CG1-CD1 4.47Å; I325-L328 WeakPolarHBondContact O-CB 3.03Å; I325-L328 PolarHBondContact O-N 2.79Å; N326-L328 VanDerWaalsContact C-N 3.35Å; N326-L328 PolarHBondContact O-N 3.14Å; L328-Y330 VanDerWaalsContact C-N 3.35Å; L328-Y330 PolarHBondContact O-N 3.41Å; L328-C331 WeakPolarHBondContact O-CB 3.32Å; L328-C331 PolarHBondContact O-N 2.89Å; L328-C331 VanDerWaalsContact O-N 3.17Å; L328-V332 WeakPolarHBondContact O-CG2 3.41Å; L328-V332 PolarHBondContact O-N 3.45Å
329	I	94.5	Very high	82.5	Confident	11 Å²	11	47.6 Å²	47.6	6%	0.056	27%	0.269	C	S	.	.	H	α-helix	trans	-60	-48	175	-60.3	166.6	0	0	0	109.4	Y275 I278 I279 A282 I325 N326 C331 V332 F333	Y275-I329 HydrophobicContact CD2-CG2 3.8Å; Y275-I329 HydrophobicContact CE2-CG2 3.92Å; I278-I329 HydrophobicContact CB-CG2 4.28Å; I278-I329 HydrophobicContact CG2-CD1 3.99Å; I278-I329 HydrophobicContact CG2-CG1 3.94Å; I278-I329 HydrophobicContact CG2-CG2 3.83Å; I279-I329 HydrophobicContact CG1-CB 4.43Å; I279-I329 HydrophobicContact CG1-CD1 3.74Å; I279-I329 HydrophobicContact CG1-CG2 4.02Å; A282-I329 HydrophobicContact CB-CD1 3.95Å; I325-I329 HydrophobicContact CG1-CD1 4.3Å; I325-I329 HydrophobicContact CG1-CG1 4.33Å; I325-I329 HydrophobicContact CG2-CD1 4.15Å; I325-I329 WeakPolarHBondContact O-CG1 3.14Å; I325-I329 PolarHBondContact O-N 3.4Å; N326-I329 PolarHBondContact O-N 3.37Å; I329-C331 VanDerWaalsContact C-N 3.31Å; I329-C331 PolarHBondContact O-N 3Å; I329-V332 PolarHBondContact O-N 2.99Å; I329-F333 HydrophobicContact CG2-CD2 3.81Å; I329-F333 HydrophobicContact CG2-CE2 3.87Å; I329-F333 VanDerWaalsContact O-CD2 3.24Å; I329-F333 WeakPolarHBondContact O-CD2 3.32Å; I329-F333 PolarHBondContact O-N 3.06Å; I329-F333 VanDerWaalsContact O-N 3.08Å
330	Y	92.3	Very high	80.1	Confident	15 Å²	15	50.8 Å²	50.8	6%	0.059	29%	0.29	C	S	.	.	H	α-helix	trans	-59.5	-39.5	175.6	176.3	-99.1	0	0	0	112.5	V70 S73 T74 V87 N326 P327 L328 F333 S334	V70-Y330 HydrophobicContact CB-CD1 4.29Å; V70-Y330 HydrophobicContact CG1-CD1 4.05Å; V70-Y330 HydrophobicContact CG1-CD2 4.47Å; V70-Y330 HydrophobicContact CG1-CE1 4.3Å; V70-Y330 HydrophobicContact CG1-CG 4.1Å; V70-Y330 HydrophobicContact CG2-CD1 3.72Å; V70-Y330 HydrophobicContact CG2-CE1 4.45Å; V70-Y330 HydrophobicContact CG2-CG 4.1Å; S73-Y330 PolarHBondContact OG-OH 3.45Å; T74-Y330 HydrophobicContact CG2-CE2 4.19Å; V87-Y330 HydrophobicContact CG1-CD2 3.53Å; V87-Y330 HydrophobicContact CG1-CE2 3.79Å; V87-Y330 HydrophobicContact CG1-CG 4.24Å; V87-Y330 HydrophobicContact CG2-CD2 4.29Å; N326-Y330 PolarHBondContact O-N 3.43Å; P327-Y330 CarbonylContact O-C 3.54Å; P327-Y330 PolarHBondContact O-N 2.02Å; L328-Y330 VanDerWaalsContact C-N 3.35Å; L328-Y330 PolarHBondContact O-N 3.41Å; Y330-F333 CarbonylContact O-C 3.6Å; Y330-F333 PolarHBondContact O-N 3Å; Y330-S334 WeakPolarHBondContact O-CA 3.16Å; Y330-S334 WeakPolarHBondContact O-CB 3.23Å; Y330-S334 PolarHBondContact O-N 3.45Å; Y330-S334 PolarHBondContact O-OG 2.75Å
331	C	90.7	Very high	77.2	Confident	60 Å²	60	56.2 Å²	56.2	41%	0.405	33%	0.326	S	S	.	.	H	α-helix	trans	-61.3	-46.6	176.8	-76.5	0	0	0	0	111.9	P327 L328 I329 F333 S334 S335	P327-C331 WeakPolarHBondContact O-CB 3.49Å; P327-C331 PolarHBondContact O-N 2.82Å; P327-C331 PolarHBondContact O-SG 3.42Å; L328-C331 WeakPolarHBondContact O-CB 3.32Å; L328-C331 PolarHBondContact O-N 2.89Å; L328-C331 VanDerWaalsContact O-N 3.17Å; I329-C331 VanDerWaalsContact C-N 3.31Å; I329-C331 PolarHBondContact O-N 3Å; C331-F333 VanDerWaalsContact C-N 3.33Å; C331-F333 PolarHBondContact O-N 2.89Å; C331-S334 WeakPolarHBondContact CA-OG 3.35Å; C331-S334 PolarHBondContact O-N 3.36Å; C331-S334 PolarHBondContact O-OG 2.97Å; C331-S335 VanDerWaalsContact O-CB 3.26Å; C331-S335 WeakPolarHBondContact O-CB 3.29Å; C331-S335 PolarHBondContact O-N 3.31Å; C331-S335 PolarHBondContact O-OG 3.07Å
332	V	90	Very high	74.2	Confident	95 Å²	95	63.7 Å²	63.7	58%	0.576	35%	0.349	S	S	*	.	H	α-helix	trans	-60.6	-42.1	176.9	172.9	0	0	0	0	111.6	L328 I329 S335	L328-V332 WeakPolarHBondContact O-CG2 3.41Å; L328-V332 PolarHBondContact O-N 3.45Å; I329-V332 PolarHBondContact O-N 2.99Å; V332-S335 PolarHBondContact O-OG 3.45Å; V332-S335 VanDerWaalsContact O-OG 3.13Å
333	F	87	Confident	71.3	Confident	21 Å²	21	70 Å²	70	9%	0.092	38%	0.378	C	S	.	.	H	α-helix	trans	-79.9	-23.4	177.3	-72.9	-77.2	0	0	0	112.8	K271 K274 Y275 I278 I329 Y330 C331 S336	K271-F333 WeakPolarHBondContact CE-O 3.34Å; K271-F333 HydrophobicContact CG-CD1 4.29Å; K271-F333 PolarHBondContact NZ-O 3.16Å; K274-F333 VanDerWaalsContact C-CZ 3.46Å; K274-F333 HydrophobicContact CB-CE1 3.45Å; K274-F333 VanDerWaalsContact CB-CE1 3.45Å; K274-F333 HydrophobicContact CB-CZ 3.8Å; Y275-F333 HydrophobicContact CD2-CB 4.23Å; Y275-F333 AromaticContact CD2-CD2 3.74Å; Y275-F333 HydrophobicContact CD2-CD2 3.74Å; Y275-F333 HydrophobicContact CD2-CE2 4.44Å; Y275-F333 HydrophobicContact CD2-CG 4.15Å; Y275-F333 HydrophobicContact CG-CD2 4.32Å; I278-F333 HydrophobicContact CB-CE2 4.15Å; I278-F333 HydrophobicContact CD1-CE2 3.65Å; I278-F333 HydrophobicContact CD1-CZ 3.53Å; I278-F333 HydrophobicContact CG1-CE2 4.15Å; I278-F333 HydrophobicContact CG1-CZ 4.07Å; I329-F333 HydrophobicContact CG2-CD2 3.81Å; I329-F333 HydrophobicContact CG2-CE2 3.87Å; I329-F333 VanDerWaalsContact O-CD2 3.24Å; I329-F333 WeakPolarHBondContact O-CD2 3.32Å; I329-F333 PolarHBondContact O-N 3.06Å; I329-F333 VanDerWaalsContact O-N 3.08Å; Y330-F333 CarbonylContact O-C 3.6Å; Y330-F333 PolarHBondContact O-N 3Å; C331-F333 VanDerWaalsContact C-N 3.33Å; C331-F333 PolarHBondContact O-N 2.89Å; F333-S336 PolarHBondContact O-OG 2.99Å
334	S	80.5	Confident	68.6	Low	14 Å²	14	77.8 Å²	77.8	10%	0.098	41%	0.414	C	S	.	.	H	α-helix	trans	-88.3	-27.8	178.4	64.6	0	0	0	0	112.7	Y330 C331 S336 I337 S338	Y330-S334 WeakPolarHBondContact O-CA 3.16Å; Y330-S334 WeakPolarHBondContact O-CB 3.23Å; Y330-S334 PolarHBondContact O-N 3.45Å; Y330-S334 PolarHBondContact O-OG 2.75Å; C331-S334 WeakPolarHBondContact CA-OG 3.35Å; C331-S334 PolarHBondContact O-N 3.36Å; C331-S334 PolarHBondContact O-OG 2.97Å; S334-S336 VanDerWaalsContact C-N 3.35Å; S334-I337 CarbonylContact O-C 3.58Å; S334-I337 VanDerWaalsContact O-CA 3.25Å; S334-I337 WeakPolarHBondContact O-CA 3.43Å; S334-I337 WeakPolarHBondContact O-CB 3.4Å; S334-I337 PolarHBondContact O-N 2.96Å; S334-S338 PolarHBondContact O-N 3.25Å; S334-S338 PolarHBondContact O-OG 3.37Å
335	S	66.1	Low	65.8	Low	58 Å²	58	88.6 Å²	88.6	41%	0.406	45%	0.453	S	S	.	.	H	α-helix	trans	-67.4	-32.8	174.1	64.2	0	0	0	0	112.7	C331 V332 I337 S338	C331-S335 VanDerWaalsContact O-CB 3.26Å; C331-S335 WeakPolarHBondContact O-CB 3.29Å; C331-S335 PolarHBondContact O-N 3.31Å; C331-S335 PolarHBondContact O-OG 3.07Å; V332-S335 PolarHBondContact O-OG 3.45Å; V332-S335 VanDerWaalsContact O-OG 3.13Å; S335-I337 PolarHBondContact O-N 3.39Å; S335-I337 VanDerWaalsContact O-N 3.16Å; S335-S338 WeakPolarHBondContact CA-OG 3.45Å; S335-S338 CarbonylContact O-C 3.39Å; S335-S338 VanDerWaalsContact O-C 3.24Å; S335-S338 WeakPolarHBondContact O-CA 3.48Å; S335-S338 PolarHBondContact O-N 3.05Å
336	S	56	Low	63.4	Low	81 Å²	81	87.5 Å²	87.5	57%	0.566	45%	0.451	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68	-7.1	166.3	58.1	0	0	0	0	113.8	K271 F333 S334	K271-S336 PolarHBondContact NZ-OG 3.31Å; F333-S336 PolarHBondContact O-OG 2.99Å; S334-S336 VanDerWaalsContact C-N 3.35Å
337	I	50.6	Low	61.1	Low	94 Å²	94	93.1 Å²	93.1	48%	0.482	48%	0.477	S	S	.	.	T	Hydrogen-bonded Turn	trans	-96.8	-22	163.9	-92.4	149.7	0	0	0	110.7	K271 S334 S335	K271-I337 HydrophobicContact CD-CD1 4.05Å; K271-I337 HydrophobicContact CD-CG1 4.44Å; K271-I337 VanDerWaalsContact NZ-CD1 3.25Å; S334-I337 CarbonylContact O-C 3.58Å; S334-I337 VanDerWaalsContact O-CA 3.25Å; S334-I337 WeakPolarHBondContact O-CA 3.43Å; S334-I337 WeakPolarHBondContact O-CB 3.4Å; S334-I337 PolarHBondContact O-N 2.96Å; S335-I337 PolarHBondContact O-N 3.39Å; S335-I337 VanDerWaalsContact O-N 3.16Å
338	S	40.6	Very low	58.8	Low	60 Å²	60	97.3 Å²	97.3	42%	0.42	50%	0.499	S	S	.	.			trans	-120.8	60.8	-170.6	73.5	0	0	0	0	114.4	S334 S335 P340	S334-S338 PolarHBondContact O-N 3.25Å; S334-S338 PolarHBondContact O-OG 3.37Å; S335-S338 WeakPolarHBondContact CA-OG 3.45Å; S335-S338 CarbonylContact O-C 3.39Å; S335-S338 VanDerWaalsContact O-C 3.24Å; S335-S338 WeakPolarHBondContact O-CA 3.48Å; S335-S338 PolarHBondContact O-N 3.05Å; S338-P340 WeakPolarHBondContact O-CD 3.47Å
339	F	29.6	Very low	56.8	Low	204 Å²	204	97.2 Å²	97.2	90%	0.895	51%	0.506	S	S	*	.			trans	-86.6	81.8	138.9	-91.2	-86.6	0	0	0	108.2
340	P	42.2	Very low	54.8	Low	92 Å²	92	106 Å²	106	60%	0.597	54%	0.538	S	S	*	.			trans	-128.1	73	142.7	38.2	-30.6	0	0	0	107.7	S338	S338-P340 WeakPolarHBondContact O-CD 3.47Å
341	C	35.7	Very low	52.9	Low	124 Å²	124	107.1 Å²	107.1	84%	0.838	55%	0.545	S	S	*	.	S	Bend	trans	-149.2	48.2	164.8	-121.2	0	0	0	0	110.4
342	R	33.2	Very low	51.7	Low	227 Å²	227	108.1 Å²	108.1	86%	0.857	55%	0.549	S	S	*	.	S	Bend	trans	-163.8	-12.3	151.4	-138.1	175.3	166.9	170.8	-4.7	118.4
343	E	34.9	Very low	50.5	Low	136 Å²	136	111.9 Å²	111.9	64%	0.636	56%	0.558	S	S	*	*	S	Bend	trans	-97.9	-21.8	-174	-132.9	85.7	-144	0	0	115.9	R345 S346 Q347	E343-R345 VanDerWaalsContact C-N 3.32Å; E343-R345 PolarHBondContact O-N 3.2Å; E343-S346 PolarHBondContact O-N 3.4Å; E343-S346 PolarHBondContact O-OG 2.87Å; E343-S346 VanDerWaalsContact O-OG 3.12Å; E343-Q347 PolarHBondContact O-N 3.44Å
344	Q	40.1	Very low	49.5	Very low	168 Å²	168	119.6 Å²	119.6	79%	0.785	59%	0.587	S	S	*	*	H	α-helix	trans	-79.3	-15.5	-169.9	-142.9	155.5	0.4	0	0	113.9
345	R	37.2	Very low	48.7	Very low	234 Å²	234	123.4 Å²	123.4	88%	0.883	60%	0.603	S	S	*	*	H	α-helix	trans	-88.7	-14.8	174.6	-135.8	175.5	-171.6	178.3	0.8	113.2	E343 S349	E343-R345 VanDerWaalsContact C-N 3.32Å; E343-R345 PolarHBondContact O-N 3.2Å; R345-S349 PolarHBondContact O-OG 2.94Å; R345-S349 VanDerWaalsContact O-OG 3.12Å
346	S	45.7	Very low	48.4	Very low	30 Å²	30	127.5 Å²	127.5	21%	0.21	61%	0.61	C	S	.	*	H	α-helix	trans	-98.7	-16.1	-179.5	62	0	0	0	0	114.7	E343	E343-S346 PolarHBondContact O-N 3.4Å; E343-S346 PolarHBondContact O-OG 2.87Å; E343-S346 VanDerWaalsContact O-OG 3.12Å
347	Q	47.6	Very low	48.6	Very low	125 Å²	125	126.5 Å²	126.5	58%	0.584	60%	0.6	S	S	*	*	H	α-helix	trans	-82.6	-32.5	175.9	-87.8	-173.9	-17.3	0	0	113.1	E343 S349 R350 M351	E343-Q347 PolarHBondContact O-N 3.44Å; Q347-S349 VanDerWaalsContact C-N 3.31Å; Q347-S349 PolarHBondContact O-N 3.35Å; Q347-R350 PolarHBondContact O-N 3.45Å; Q347-M351 PolarHBondContact O-N 2.96Å
348	D	47.1	Very low	49.3	Very low	96 Å²	96	126 Å²	126	51%	0.513	60%	0.596	S	S	.	*	S	Bend	trans	-77.3	-20.5	-177	-132.2	13.5	0	0	0	113.1
349	S	51.2	Low	50.3	Low	96 Å²	96	128.7 Å²	128.7	67%	0.671	60%	0.597	S	S	*	*	S	Bend	trans	-89.5	-16	176.8	34.8	0	0	0	0	113.8	R345 Q347	R345-S349 PolarHBondContact O-OG 2.94Å; R345-S349 VanDerWaalsContact O-OG 3.12Å; Q347-S349 VanDerWaalsContact C-N 3.31Å; Q347-S349 PolarHBondContact O-N 3.35Å
350	R	51.8	Low	51.6	Low	195 Å²	195	124.5 Å²	124.5	74%	0.736	58%	0.58	S	S	*	*	S	Bend	trans	-101.8	-1.7	177	-92.2	-171.4	-86.7	-171.2	-7.8	114.3	Q347 T352	Q347-R350 PolarHBondContact O-N 3.45Å; R350-T352 PolarHBondContact O-N 2.96Å
351	M	53.2	Low	52	Low	40 Å²	40	126 Å²	126	20%	0.197	58%	0.578	C	S	.	*			trans	-73.4	119.8	-178.7	-149	155.2	-73.6	0	0	110.1	Q347 E355 R359	Q347-M351 PolarHBondContact O-N 2.96Å; M351-E355 WeakPolarHBondContact CA-OE2 3.11Å; M351-E355 HydrophobicContact CG-CB 3.5Å; M351-E355 VanDerWaalsContact CG-CB 3.5Å; M351-E355 HydrophobicContact SD-CB 4.43Å; M351-R359 PolarHBondContact SD-NH2 2.82Å
352	T	65.1	Low	53	Low	81 Å²	81	126.3 Å²	126.3	50%	0.497	57%	0.569	S	S	.	*			trans	-69.5	154.1	175.3	58.7	0	0	0	0	110	R350 R354 E355 R356	R350-T352 PolarHBondContact O-N 2.96Å; T352-R354 PolarHBondContact O-N 2.8Å; T352-R354 VanDerWaalsContact O-N 3.08Å; T352-E355 PolarHBondContact N-OE2 2.86Å; T352-E355 PolarHBondContact O-N 2.98Å; T352-E355 WeakPolarHBondContact OG1-CG 3.42Å; T352-E355 PolarHBondContact OG1-OE2 3.38Å; T352-R356 PolarHBondContact O-N 2.87Å
353	F	65.2	Low	53.9	Low	173 Å²	173	120.9 Å²	120.9	76%	0.759	55%	0.554	S	S	*	*	H	α-helix	trans	-51.6	-36.6	-179.4	-177.5	-102	0	0	0	112.3	R356 T357	F353-R356 PolarHBondContact O-N 3.23Å; F353-T357 PolarHBondContact O-N 2.93Å; F353-T357 VanDerWaalsContact O-N 3.11Å; F353-T357 PolarHBondContact O-OG1 3.41Å
354	R	65.9	Low	54.6	Low	184 Å²	184	120.4 Å²	120.4	69%	0.694	55%	0.554	S	S	*	*	H	α-helix	trans	-62.4	-44.3	176.9	-172.1	175.4	174.5	166.8	2.3	113.3	T352 R356 T357 E358	T352-R354 PolarHBondContact O-N 2.8Å; T352-R354 VanDerWaalsContact O-N 3.08Å; R354-R356 VanDerWaalsContact C-N 3.28Å; R354-R356 PolarHBondContact O-N 3.46Å; R354-T357 PolarHBondContact O-N 3.47Å; R354-E358 IonicContact NE-OE1 3.12Å; R354-E358 PolarHBondContact O-N 2.87Å
355	E	64	Low	54.9	Low	93 Å²	93	120 Å²	120	44%	0.435	56%	0.557	S	S	.	*	H	α-helix	trans	-67.7	-29.7	177.4	-70.3	170.1	140.8	0	0	112.2	M351 T352 R359	M351-E355 WeakPolarHBondContact CA-OE2 3.11Å; M351-E355 HydrophobicContact CG-CB 3.5Å; M351-E355 VanDerWaalsContact CG-CB 3.5Å; M351-E355 HydrophobicContact SD-CB 4.43Å; T352-E355 PolarHBondContact N-OE2 2.86Å; T352-E355 PolarHBondContact O-N 2.98Å; T352-E355 WeakPolarHBondContact OG1-CG 3.42Å; T352-E355 PolarHBondContact OG1-OE2 3.38Å; E355-R359 WeakPolarHBondContact O-CB 3.4Å; E355-R359 PolarHBondContact O-N 2.87Å; E355-R359 VanDerWaalsContact O-N 3.17Å
356	R	59.6	Low	55.3	Low	145 Å²	145	112.9 Å²	112.9	55%	0.547	54%	0.543	S	S	.	.	H	α-helix	trans	-69.3	-39.3	174	-171	177.2	-82.6	179.6	-4.3	111.3	T352 F353 R354 H360	T352-R356 PolarHBondContact O-N 2.87Å; F353-R356 PolarHBondContact O-N 3.23Å; R354-R356 VanDerWaalsContact C-N 3.28Å; R354-R356 PolarHBondContact O-N 3.46Å; R356-H360 PolarHBondContact O-N 2.72Å; R356-H360 VanDerWaalsContact O-N 3.11Å
357	T	61	Low	55	Low	60 Å²	60	119.7 Å²	119.7	37%	0.368	57%	0.568	S	S	.	*	H	α-helix	trans	-66.9	-47.2	176.6	-44.7	0	0	0	0	111.6	F353 R354 R359 H360 E361	F353-T357 PolarHBondContact O-N 2.93Å; F353-T357 VanDerWaalsContact O-N 3.11Å; F353-T357 PolarHBondContact O-OG1 3.41Å; R354-T357 PolarHBondContact O-N 3.47Å; T357-R359 VanDerWaalsContact C-N 3.27Å; T357-R359 PolarHBondContact O-N 2.73Å; T357-H360 WeakPolarHBondContact O-CA 3.5Å; T357-H360 WeakPolarHBondContact O-CB 3.32Å; T357-H360 PolarHBondContact O-N 3.12Å; T357-E361 PolarHBondContact O-N 3.3Å
358	E	63.6	Low	54.8	Low	84 Å²	84	118.3 Å²	118.3	39%	0.393	57%	0.57	S	S	.	*	H	α-helix	trans	-61.2	-35.6	178.1	-72.2	175.2	-173.5	0	0	112.1	R354 E361 M362	R354-E358 IonicContact NE-OE1 3.12Å; R354-E358 PolarHBondContact O-N 2.87Å; E358-E361 PolarHBondContact O-N 3.27Å; E358-M362 PolarHBondContact O-N 3.29Å
359	R	63.1	Low	54.6	Low	116 Å²	116	122.8 Å²	122.8	44%	0.438	59%	0.588	S	S	.	*	H	α-helix	trans	-69.5	-36.3	174.3	-163.8	-168.1	-74.3	-176.3	-12.4	112.3	M351 E355 T357 Q363	M351-R359 PolarHBondContact SD-NH2 2.82Å; E355-R359 WeakPolarHBondContact O-CB 3.4Å; E355-R359 PolarHBondContact O-N 2.87Å; E355-R359 VanDerWaalsContact O-N 3.17Å; T357-R359 VanDerWaalsContact C-N 3.27Å; T357-R359 PolarHBondContact O-N 2.73Å; R359-Q363 WeakPolarHBondContact O-CG 3.43Å; R359-Q363 PolarHBondContact O-N 2.81Å
360	H	55.6	Low	54.3	Low	116 Å²	116	127.4 Å²	127.4	54%	0.537	60%	0.597	S	S	.	*	H	α-helix	trans	-66.3	-42	173.7	-111.1	54.3	0	0	0	111.4	R356 T357 M362 Q363 I364	R356-H360 PolarHBondContact O-N 2.72Å; R356-H360 VanDerWaalsContact O-N 3.11Å; T357-H360 WeakPolarHBondContact O-CA 3.5Å; T357-H360 WeakPolarHBondContact O-CB 3.32Å; T357-H360 PolarHBondContact O-N 3.12Å; H360-M362 PolarHBondContact O-N 3.02Å; H360-Q363 PolarHBondContact O-N 2.83Å; H360-Q363 VanDerWaalsContact O-N 3.16Å; H360-I364 VanDerWaalsContact O-CG1 3.29Å; H360-I364 WeakPolarHBondContact O-CG1 3.4Å; H360-I364 PolarHBondContact O-N 2.98Å
361	E	51.2	Low	53.9	Low	122 Å²	122	129 Å²	129	57%	0.57	62%	0.617	S	S	*	*	H	α-helix	trans	-61.8	-43.3	175.6	-72.8	-178.3	161.1	0	0	111.9	T357 E358 Q363 I364 L365	T357-E361 PolarHBondContact O-N 3.3Å; E358-E361 PolarHBondContact O-N 3.27Å; E361-Q363 VanDerWaalsContact C-N 3.31Å; E361-Q363 PolarHBondContact O-N 3.24Å; E361-I364 PolarHBondContact O-N 3.12Å; E361-L365 PolarHBondContact O-N 2.93Å
362	M	56.2	Low	54	Low	132 Å²	132	133.5 Å²	133.5	65%	0.65	64%	0.639	S	S	*	*	H	α-helix	trans	-65.5	-30.4	174.3	-75	-168.2	-116	0	0	113.5	E358 H360 S366	E358-M362 PolarHBondContact O-N 3.29Å; H360-M362 PolarHBondContact O-N 3.02Å; M362-S366 PolarHBondContact O-N 2.78Å; M362-S366 PolarHBondContact O-OG 3.32Å
363	Q	52.5	Low	53.4	Low	113 Å²	113	136.3 Å²	136.3	53%	0.528	65%	0.646	S	S	.	*	H	α-helix	trans	-74.9	-31.5	174.9	-80.8	-175.9	-18.7	0	0	112.8	R359 H360 E361 S366	R359-Q363 WeakPolarHBondContact O-CG 3.43Å; R359-Q363 PolarHBondContact O-N 2.81Å; H360-Q363 PolarHBondContact O-N 2.83Å; H360-Q363 VanDerWaalsContact O-N 3.16Å; E361-Q363 VanDerWaalsContact C-N 3.31Å; E361-Q363 PolarHBondContact O-N 3.24Å; Q363-S366 WeakPolarHBondContact CA-OG 3.11Å; Q363-S366 PolarHBondContact O-OG 2.8Å
364	I	50.5	Low	52.7	Low	125 Å²	125	134.2 Å²	134.2	64%	0.641	64%	0.64	S	S	*	*	H	α-helix	trans	-69.8	-41.9	173.3	-66.1	164	0	0	0	109.8	H360 E361 S366 K367	H360-I364 VanDerWaalsContact O-CG1 3.29Å; H360-I364 WeakPolarHBondContact O-CG1 3.4Å; H360-I364 PolarHBondContact O-N 2.98Å; E361-I364 PolarHBondContact O-N 3.12Å; I364-S366 PolarHBondContact O-N 3.15Å; I364-K367 PolarHBondContact O-N 2.96Å
365	L	46.8	Very low	51.9	Low	160 Å²	160	131.3 Å²	131.3	84%	0.838	64%	0.636	S	S	*	*	H	α-helix	trans	-69.3	-15.7	-179.4	-134.7	112.6	0	0	0	114.3	E361	E361-L365 PolarHBondContact O-N 2.93Å
366	S	44.6	Very low	51.2	Low	84 Å²	84	133.7 Å²	133.7	59%	0.587	65%	0.649	S	S	*	*	T	Hydrogen-bonded Turn	trans	-98.4	6.1	-177.6	52.4	0	0	0	0	114.5	M362 Q363 I364 P368	M362-S366 PolarHBondContact O-N 2.78Å; M362-S366 PolarHBondContact O-OG 3.32Å; Q363-S366 WeakPolarHBondContact CA-OG 3.11Å; Q363-S366 PolarHBondContact O-OG 2.8Å; I364-S366 PolarHBondContact O-N 3.15Å; S366-P368 VanDerWaalsContact O-CD 3.24Å; S366-P368 WeakPolarHBondContact O-CD 3.26Å
367	K	40	Very low	50.6	Low	173 Å²	173	132.9 Å²	132.9	75%	0.752	66%	0.656	S	S	*	*	S	Bend	trans	-87.1	108.7	162.9	-80.5	-173.9	176.8	180	0	108.9	I364 E369	I364-K367 PolarHBondContact O-N 2.96Å; K367-E369 PolarHBondContact O-N 3.33Å
368	P	43.5	Very low	49.9	Very low	96 Å²	96	138.1 Å²	138.1	62%	0.623	68%	0.676	S	S	*	*			trans	-65.6	122.5	170.9	26.9	-30.4	0	0	0	108.2	S366 F370	S366-P368 VanDerWaalsContact O-CD 3.24Å; S366-P368 WeakPolarHBondContact O-CD 3.26Å; P368-F370 HydrophobicContact CG-CD2 4.41Å; P368-F370 HydrophobicContact CG-CE2 4.01Å; P368-F370 PolarHBondContact O-N 2.82Å
369	E	42.1	Very low	48.8	Very low	190 Å²	190	142.3 Å²	142.3	89%	0.888	70%	0.698	S	S	*	*			trans	-61.6	102.5	163.7	-71.6	-177.6	158.8	0	0	107.3	K367 I371	K367-E369 PolarHBondContact O-N 3.33Å; E369-I371 PolarHBondContact O-N 3.46Å
370	F	45.9	Very low	47.7	Very low	194 Å²	194	144.5 Å²	144.5	85%	0.851	72%	0.72	S	S	*	*			trans	-71.8	108.2	163.4	-81.1	-90.3	0	0	0	107.1	P368	P368-F370 HydrophobicContact CG-CD2 4.41Å; P368-F370 HydrophobicContact CG-CE2 4.01Å; P368-F370 PolarHBondContact O-N 2.82Å
371	I	43.1	Very low	46.9	Very low	229 Å²	229	147.1 Å²	147.1	100%	1.174	74%	0.737	S	S	*	*			trans	-80.6	0	151.5	-66.6	173.9	0	0	0	107.6	E369	E369-I371 PolarHBondContact O-N 3.46Å

Retrieved 371 of 371 residues in 276.2 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).