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Signal peptide peptidase-like 3

Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane protein substrates in or close to their luminal transmembrane domain boundaries^1,2,3. Acts like a sheddase by mediating the proteolytic release and secretion of active site-containing ectodomains of glycan-modifiying glycosidase and glycosyltransferase enzymes such as MGAT5, B4GAT1 and B4GALT1^4,5. Catalyzes the intramembrane cleavage of the envelope glycoprotein gp130 and/or the leader peptide gp18LP of the simian foamy virus independent of prior ectodomain shedding by furin or furin-like proprotein convertase (PC)-mediated cleavage proteolysis⁶. May also have the ability to serve as a shedding protease for subsequent intramembrane proteolysis by SPPL2A and SPPL2B of the envelope glycoprotein gp130⁷. Plays a role in the regulation of cellular glycosylation processes⁸. Required to link T-cell antigen receptor (TCR) and calcineurin-NFAT signaling cascades in lymphocytes by promoting the association of STIM1 and ORAI1 during store-operated calcium entry (SOCE) in a protease-independent manner⁹.

AlphaFold DB , UniProt , Accession Q8TCT6, Species HUMAN (Homo sapiens, Human), Gene SPPL3, Length 384 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	48.3	Very low	51.4	Low	205 Å²	205	125.1 Å²	125.1	100%	1.01	63%	0.628	S	S	*	*				0	-47.2	0	-146.3	179.6	-73	0	0	111.9	Q4 T5	M1-Q4 PolarHBondContact O-N 2.88Å; M1-T5 PolarHBondContact O-N 2.7Å; M1-T5 PolarHBondContact O-OG1 3.35Å
2	A	49.4	Very low	51.3	Low	56 Å²	56	120.3 Å²	120.3	46%	0.463	61%	0.605	S	S	.	*	H	α-helix	trans	-62	-46.2	175.5	0	0	0	0	0	113.5	Q4 T5 Y6	A2-Q4 PolarHBondContact O-N 3.25Å; A2-T5 WeakPolarHBondContact CA-OG1 3.42Å; A2-T5 PolarHBondContact O-N 3.15Å; A2-T5 PolarHBondContact O-OG1 3.35Å; A2-T5 VanDerWaalsContact O-OG1 3.08Å; A2-Y6 HydrophobicContact CB-CD2 4.38Å; A2-Y6 HydrophobicContact CB-CE2 3.95Å; A2-Y6 WeakPolarHBondContact O-CD2 3.41Å; A2-Y6 PolarHBondContact O-N 3.13Å
3	E	49.7	Very low	51.8	Low	168 Å²	168	117.3 Å²	117.3	79%	0.785	60%	0.596	S	S	*	*	H	α-helix	trans	-59.6	-35.3	177.6	-69.1	-156.9	152.9	0	0	113.5	T5 Y6 S7	E3-T5 VanDerWaalsContact C-N 3.34Å; E3-Y6 PolarHBondContact O-N 3.28Å; E3-S7 PolarHBondContact O-N 3.37Å; E3-S7 PolarHBondContact O-OG 2.88Å
4	Q	51.5	Low	53.1	Low	147 Å²	147	111.5 Å²	111.5	69%	0.687	57%	0.567	S	S	*	*	H	α-helix	trans	-73.7	-27.3	178.9	-151.1	159.6	7.4	0	0	112.2	M1 A2 S7 W8	M1-Q4 PolarHBondContact O-N 2.88Å; A2-Q4 PolarHBondContact O-N 3.25Å; Q4-S7 WeakPolarHBondContact CA-OG 3.39Å; Q4-S7 PolarHBondContact O-OG 3.43Å; Q4-W8 WeakPolarHBondContact O-CB 3.48Å; Q4-W8 PolarHBondContact O-N 2.71Å
5	T	52.2	Low	54.6	Low	88 Å²	88	109.6 Å²	109.6	54%	0.54	57%	0.568	S	S	.	*	H	α-helix	trans	-76.4	-38.2	172	0.8	0	0	0	0	111.4	M1 A2 E3 W8 A9	M1-T5 PolarHBondContact O-N 2.7Å; M1-T5 PolarHBondContact O-OG1 3.35Å; A2-T5 WeakPolarHBondContact CA-OG1 3.42Å; A2-T5 PolarHBondContact O-N 3.15Å; A2-T5 PolarHBondContact O-OG1 3.35Å; A2-T5 VanDerWaalsContact O-OG1 3.08Å; E3-T5 VanDerWaalsContact C-N 3.34Å; T5-W8 VanDerWaalsContact O-CB 3.31Å; T5-W8 WeakPolarHBondContact O-CB 3.46Å; T5-W8 PolarHBondContact O-N 3.23Å; T5-A9 PolarHBondContact O-N 3.16Å
6	Y	52.2	Low	56	Low	151 Å²	151	103.1 Å²	103.1	59%	0.592	54%	0.535	S	S	*	.	H	α-helix	trans	-67	-43.5	174.5	-67.5	-64.8	0	0	0	111.8	A2 E3 W8 A9 Y10	A2-Y6 HydrophobicContact CB-CD2 4.38Å; A2-Y6 HydrophobicContact CB-CE2 3.95Å; A2-Y6 WeakPolarHBondContact O-CD2 3.41Å; A2-Y6 PolarHBondContact O-N 3.13Å; E3-Y6 PolarHBondContact O-N 3.28Å; Y6-W8 PolarHBondContact O-N 3.48Å; Y6-A9 PolarHBondContact O-N 2.74Å; Y6-A9 VanDerWaalsContact O-N 3.14Å; Y6-Y10 WeakPolarHBondContact O-CD2 3.33Å; Y6-Y10 PolarHBondContact O-N 2.98Å
7	S	52.7	Low	57.4	Low	69 Å²	69	99.1 Å²	99.1	48%	0.483	51%	0.513	S	S	.	.	H	α-helix	trans	-60.8	-32.7	172.1	64.1	0	0	0	0	111.9	E3 Q4 S11	E3-S7 PolarHBondContact O-N 3.37Å; E3-S7 PolarHBondContact O-OG 2.88Å; Q4-S7 WeakPolarHBondContact CA-OG 3.39Å; Q4-S7 PolarHBondContact O-OG 3.43Å; S7-S11 WeakPolarHBondContact O-CB 3.34Å; S7-S11 PolarHBondContact O-N 2.92Å
8	W	48.5	Very low	58.8	Low	176 Å²	176	97.1 Å²	97.1	67%	0.667	51%	0.506	S	S	*	.	H	α-helix	trans	-67.1	-46.2	173.3	-127.9	60.9	0	0	0	111.5	Q4 T5 Y6 S11 L12	Q4-W8 WeakPolarHBondContact O-CB 3.48Å; Q4-W8 PolarHBondContact O-N 2.71Å; T5-W8 VanDerWaalsContact O-CB 3.31Å; T5-W8 WeakPolarHBondContact O-CB 3.46Å; T5-W8 PolarHBondContact O-N 3.23Å; Y6-W8 PolarHBondContact O-N 3.48Å; W8-S11 CarbonylContact O-C 3.04Å; W8-S11 PolarHBondContact O-N 3.39Å; W8-L12 HydrophobicContact CD2-CD1 4.35Å; W8-L12 HydrophobicContact CE3-CD1 3.57Å; W8-L12 HydrophobicContact CE3-CD2 4.44Å; W8-L12 HydrophobicContact CE3-CG 4.11Å; W8-L12 HydrophobicContact CZ3-CD1 4.07Å; W8-L12 HydrophobicContact CZ3-CD2 4.4Å; W8-L12 WeakPolarHBondContact O-CA 3.35Å; W8-L12 WeakPolarHBondContact O-CB 3.49Å; W8-L12 WeakPolarHBondContact O-CD1 3.39Å; W8-L12 WeakPolarHBondContact O-CG 3.16Å; W8-L12 PolarHBondContact O-N 3.04Å
9	A	52	Low	60.1	Low	49 Å²	49	94 Å²	94	41%	0.405	49%	0.494	S	S	.	.	H	α-helix	trans	-64.7	-42.6	178.6	0	0	0	0	0	113.1	T5 Y6 S11 L12 V13	T5-A9 PolarHBondContact O-N 3.16Å; Y6-A9 PolarHBondContact O-N 2.74Å; Y6-A9 VanDerWaalsContact O-N 3.14Å; A9-S11 VanDerWaalsContact C-N 3.34Å; A9-L12 PolarHBondContact O-N 3.35Å; A9-V13 PolarHBondContact O-N 3.04Å
10	Y	52.7	Low	61.4	Low	193 Å²	193	89.5 Å²	89.5	76%	0.757	47%	0.47	S	S	*	.	H	α-helix	trans	-71	-26.7	175.5	-80.3	-78.5	0	0	0	113	Y6	Y6-Y10 WeakPolarHBondContact O-CD2 3.33Å; Y6-Y10 PolarHBondContact O-N 2.98Å
11	S	56.5	Low	62.7	Low	74 Å²	74	86.1 Å²	86.1	52%	0.517	45%	0.452	S	S	.	.	H	α-helix	trans	-82.2	-31.6	172.2	177.8	0	0	0	0	113.3	S7 W8 A9 V13 R334	S7-S11 WeakPolarHBondContact O-CB 3.34Å; S7-S11 PolarHBondContact O-N 2.92Å; W8-S11 CarbonylContact O-C 3.04Å; W8-S11 PolarHBondContact O-N 3.39Å; A9-S11 VanDerWaalsContact C-N 3.34Å; S11-V13 PolarHBondContact O-N 2.97Å; S11-R334 PolarHBondContact O-NH1 3.08Å; S11-R334 PolarHBondContact O-NH2 3.18Å
12	L	50	Low	64.7	Low	68 Å²	68	80.8 Å²	80.8	36%	0.356	43%	0.427	S	S	.	.	H	α-helix	trans	-61.7	-34.5	176.7	-87.8	167.4	0	0	0	110.7	W8 A9 Q17 R334	W8-L12 HydrophobicContact CD2-CD1 4.35Å; W8-L12 HydrophobicContact CE3-CD1 3.57Å; W8-L12 HydrophobicContact CE3-CD2 4.44Å; W8-L12 HydrophobicContact CE3-CG 4.11Å; W8-L12 HydrophobicContact CZ3-CD1 4.07Å; W8-L12 HydrophobicContact CZ3-CD2 4.4Å; W8-L12 WeakPolarHBondContact O-CA 3.35Å; W8-L12 WeakPolarHBondContact O-CB 3.49Å; W8-L12 WeakPolarHBondContact O-CD1 3.39Å; W8-L12 WeakPolarHBondContact O-CG 3.16Å; W8-L12 PolarHBondContact O-N 3.04Å; A9-L12 PolarHBondContact O-N 3.35Å; L12-Q17 PolarHBondContact O-OE1 3.27Å; L12-R334 PolarHBondContact O-NH2 3.22Å; L12-R334 VanDerWaalsContact O-NH2 3.08Å
13	V	57.6	Low	66.7	Low	81 Å²	81	79.9 Å²	79.9	49%	0.491	41%	0.414	S	S	.	.	S	Bend	trans	-108.4	71.3	178.9	-176.1	0	0	0	0	107.9	A9 S11 S15 V18	A9-V13 PolarHBondContact O-N 3.04Å; S11-V13 PolarHBondContact O-N 2.97Å; V13-S15 PolarHBondContact O-N 3.44Å; V13-V18 HydrophobicContact CB-CG2 4.32Å; V13-V18 HydrophobicContact CG1-CB 4.36Å; V13-V18 HydrophobicContact CG1-CG2 2.87Å
14	D	69.5	Low	68.8	Low	36 Å²	36	71.9 Å²	71.9	19%	0.193	38%	0.376	C	S	.	.			trans	-53.6	132	168.7	-176.3	7.4	0	0	0	107.4	S16 Q17 V18 S258	D14-S16 PolarHBondContact O-N 2.75Å; D14-S16 PolarHBondContact OD2-OG 3.29Å; D14-Q17 HydrophobicContact CB-CG 4.3Å; D14-Q17 PolarHBondContact O-N 3.12Å; D14-V18 PolarHBondContact O-N 3.31Å; D14-S258 PolarHBondContact OD1-OG 3.31Å; D14-S258 VanDerWaalsContact OD1-OG 3.13Å; D14-S258 PolarHBondContact OD2-OG 3.31Å
15	S	76.8	Confident	70.8	Confident	83 Å²	83	66.8 Å²	66.8	58%	0.58	35%	0.353	S	S	*	.	H	α-helix	trans	-52	-31.3	-178.3	-176.1	0	0	0	0	111.3	V13 S19	V13-S15 PolarHBondContact O-N 3.44Å; S15-S19 WeakPolarHBondContact O-CB 3.35Å; S15-S19 PolarHBondContact O-N 2.78Å; S15-S19 VanDerWaalsContact O-N 3.1Å
16	S	76.7	Confident	72.8	Confident	6 Å²	6	67.5 Å²	67.5	4%	0.042	35%	0.353	C	S	.	.	H	α-helix	trans	-62	-43.4	174.2	74	0	0	0	0	112.5	D14 S19 T20	D14-S16 PolarHBondContact O-N 2.75Å; D14-S16 PolarHBondContact OD2-OG 3.29Å; S16-S19 PolarHBondContact O-N 2.62Å; S16-S19 PolarHBondContact O-OG 3.04Å; S16-T20 WeakPolarHBondContact O-CG2 3.34Å; S16-T20 PolarHBondContact O-N 3.43Å
17	Q	78.6	Confident	74.9	Confident	34 Å²	34	61 Å²	61	16%	0.159	33%	0.329	C	S	.	.	H	α-helix	trans	-71.6	-37.6	-179	-67.2	-178.5	-11.2	0	0	112.4	L12 D14 S19 T20 F21 R334	L12-Q17 PolarHBondContact O-OE1 3.27Å; D14-Q17 HydrophobicContact CB-CG 4.3Å; D14-Q17 PolarHBondContact O-N 3.12Å; Q17-S19 VanDerWaalsContact C-N 3.28Å; Q17-S19 PolarHBondContact O-N 3.11Å; Q17-T20 PolarHBondContact O-N 3.22Å; Q17-T20 PolarHBondContact O-OG1 3.2Å; Q17-F21 WeakPolarHBondContact O-CD1 3.14Å; Q17-F21 WeakPolarHBondContact O-CG 3.47Å; Q17-F21 PolarHBondContact O-N 3.44Å; Q17-R334 VanDerWaalsContact CD-NH2 3.29Å
18	V	83.5	Confident	76.9	Confident	64 Å²	64	57.8 Å²	57.8	39%	0.388	31%	0.306	S	S	.	.	H	α-helix	trans	-60.3	-45.6	171.3	-175.5	0	0	0	0	110.2	V13 D14 T20 F21 L22	V13-V18 HydrophobicContact CB-CG2 4.32Å; V13-V18 HydrophobicContact CG1-CB 4.36Å; V13-V18 HydrophobicContact CG1-CG2 2.87Å; D14-V18 PolarHBondContact O-N 3.31Å; V18-T20 VanDerWaalsContact C-N 3.31Å; V18-T20 PolarHBondContact O-N 2.87Å; V18-F21 PolarHBondContact O-N 3.31Å; V18-L22 VanDerWaalsContact O-CB 3.26Å; V18-L22 WeakPolarHBondContact O-CB 3.45Å; V18-L22 PolarHBondContact O-N 3.38Å
19	S	83.9	Confident	79.2	Confident	38 Å²	38	51 Å²	51	27%	0.266	28%	0.284	S	S	.	.	H	α-helix	trans	-61.5	-42.3	179.9	76.3	0	0	0	0	111	S15 S16 Q17 F21 L22 I23	S15-S19 WeakPolarHBondContact O-CB 3.35Å; S15-S19 PolarHBondContact O-N 2.78Å; S15-S19 VanDerWaalsContact O-N 3.1Å; S16-S19 PolarHBondContact O-N 2.62Å; S16-S19 PolarHBondContact O-OG 3.04Å; Q17-S19 VanDerWaalsContact C-N 3.28Å; Q17-S19 PolarHBondContact O-N 3.11Å; S19-F21 PolarHBondContact O-N 3.31Å; S19-L22 PolarHBondContact O-N 3.08Å; S19-I23 VanDerWaalsContact O-CB 3.31Å; S19-I23 WeakPolarHBondContact O-CB 3.38Å; S19-I23 VanDerWaalsContact O-CD1 3.3Å; S19-I23 WeakPolarHBondContact O-CD1 3.24Å; S19-I23 WeakPolarHBondContact O-CG1 3.48Å; S19-I23 PolarHBondContact O-N 3.46Å
20	T	84.8	Confident	81.2	Confident	4 Å²	4	53.9 Å²	53.9	3%	0.025	29%	0.285	C	S	.	.	H	α-helix	trans	-64.4	-41.1	178.1	68	0	0	0	0	111.7	S16 Q17 V18 S24 F256 S265	S16-T20 WeakPolarHBondContact O-CG2 3.34Å; S16-T20 PolarHBondContact O-N 3.43Å; Q17-T20 PolarHBondContact O-N 3.22Å; Q17-T20 PolarHBondContact O-OG1 3.2Å; V18-T20 VanDerWaalsContact C-N 3.31Å; V18-T20 PolarHBondContact O-N 2.87Å; T20-S24 WeakPolarHBondContact O-CB 3.46Å; T20-S24 PolarHBondContact O-N 3.12Å; T20-S24 PolarHBondContact O-OG 2.86Å; T20-F256 HydrophobicContact CG2-CB 4.33Å; T20-F256 HydrophobicContact CG2-CD2 3.19Å; T20-F256 HydrophobicContact CG2-CE2 3.64Å; T20-F256 HydrophobicContact CG2-CG 3.96Å; T20-S265 WeakPolarHBondContact CG2-OG 3.46Å
21	F	89.6	Confident	83.2	Confident	19 Å²	19	44.7 Å²	44.7	8%	0.083	25%	0.249	C	C	.	.	H	α-helix	trans	-66.2	-46.4	178.6	-65.6	-0.9	0	0	0	111.5	Q17 V18 S19 S24 I25 F323 L326 L327 T330	Q17-F21 WeakPolarHBondContact O-CD1 3.14Å; Q17-F21 WeakPolarHBondContact O-CG 3.47Å; Q17-F21 PolarHBondContact O-N 3.44Å; V18-F21 PolarHBondContact O-N 3.31Å; S19-F21 PolarHBondContact O-N 3.31Å; F21-S24 PolarHBondContact O-N 3.43Å; F21-I25 WeakPolarHBondContact O-CG1 3.44Å; F21-I25 PolarHBondContact O-N 3.34Å; F21-F323 HydrophobicContact CD2-CE2 4.07Å; F21-L326 HydrophobicContact CB-CD2 4.17Å; F21-L326 HydrophobicContact CD1-CD2 3.19Å; F21-L326 HydrophobicContact CD1-CG 3.6Å; F21-L326 HydrophobicContact CE1-CD1 4.24Å; F21-L326 HydrophobicContact CE1-CD2 3.66Å; F21-L326 HydrophobicContact CE1-CG 3.47Å; F21-L326 VanDerWaalsContact CE1-CG 3.47Å; F21-L326 HydrophobicContact CG-CD2 3.77Å; F21-L326 HydrophobicContact CG-CG 4.34Å; F21-L326 HydrophobicContact CZ-CG 4.12Å; F21-L327 HydrophobicContact CE2-CD1 4.16Å; F21-T330 HydrophobicContact CE1-CG2 3.57Å; F21-T330 HydrophobicContact CZ-CG2 3.39Å
22	L	90.8	Very high	85	Confident	93 Å²	93	41.2 Å²	41.2	49%	0.487	23%	0.225	S	C	.	.	H	α-helix	trans	-61.3	-47.6	179	-172.5	158.5	0	0	0	110.2	V18 S19 S24 I25 L26	V18-L22 VanDerWaalsContact O-CB 3.26Å; V18-L22 WeakPolarHBondContact O-CB 3.45Å; V18-L22 PolarHBondContact O-N 3.38Å; S19-L22 PolarHBondContact O-N 3.08Å; L22-S24 PolarHBondContact O-N 2.98Å; L22-I25 PolarHBondContact O-N 2.91Å; L22-L26 HydrophobicContact CD2-CD1 3.41Å; L22-L26 VanDerWaalsContact CD2-CD1 3.41Å; L22-L26 HydrophobicContact CD2-CG 3.91Å; L22-L26 WeakPolarHBondContact O-CB 3.15Å; L22-L26 WeakPolarHBondContact O-CG 2.95Å; L22-L26 PolarHBondContact O-N 3.03Å
23	I	91.2	Very high	87	Confident	36 Å²	36	43.3 Å²	43.3	19%	0.185	23%	0.231	C	C	.	.	H	α-helix	trans	-62.4	-44.9	178.7	-68.9	163.2	0	0	0	110.4	S19 I25 L26 L27 M171 F256	S19-I23 VanDerWaalsContact O-CB 3.31Å; S19-I23 WeakPolarHBondContact O-CB 3.38Å; S19-I23 VanDerWaalsContact O-CD1 3.3Å; S19-I23 WeakPolarHBondContact O-CD1 3.24Å; S19-I23 WeakPolarHBondContact O-CG1 3.48Å; S19-I23 PolarHBondContact O-N 3.46Å; I23-I25 VanDerWaalsContact C-N 3.34Å; I23-I25 PolarHBondContact O-N 2.97Å; I23-L26 PolarHBondContact O-N 3.38Å; I23-L27 HydrophobicContact CG2-CD1 3.82Å; I23-L27 HydrophobicContact CG2-CG 4.16Å; I23-L27 VanDerWaalsContact O-CG 3.22Å; I23-L27 WeakPolarHBondContact O-CG 2.98Å; I23-L27 PolarHBondContact O-N 3.04Å; I23-M171 HydrophobicContact CG2-SD 3.94Å; I23-F256 HydrophobicContact CB-CZ 4.42Å; I23-F256 HydrophobicContact CD1-CD1 4.2Å; I23-F256 HydrophobicContact CD1-CE1 3.24Å; I23-F256 HydrophobicContact CD1-CE2 4.36Å; I23-F256 HydrophobicContact CD1-CZ 3.33Å; I23-F256 HydrophobicContact CG1-CZ 4.46Å; I23-F256 HydrophobicContact CG2-CZ 4.23Å
24	S	92.7	Very high	88.6	Confident	0 Å²	0	40.7 Å²	40.7	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-59.1	-45.1	178.1	-56.9	0	0	0	0	112.1	T20 F21 L22 L27 I28 L267 I272	T20-S24 WeakPolarHBondContact O-CB 3.46Å; T20-S24 PolarHBondContact O-N 3.12Å; T20-S24 PolarHBondContact O-OG 2.86Å; F21-S24 PolarHBondContact O-N 3.43Å; L22-S24 PolarHBondContact O-N 2.98Å; S24-L27 PolarHBondContact O-N 2.71Å; S24-I28 VanDerWaalsContact O-CG1 3.31Å; S24-I28 WeakPolarHBondContact O-CG1 3.33Å; S24-I28 PolarHBondContact O-N 2.95Å; S24-L267 WeakPolarHBondContact OG-CD2 3.38Å; S24-I272 WeakPolarHBondContact OG-CD1 3.42Å
25	I	94.6	Very high	89.7	Confident	40 Å²	40	39 Å²	39	21%	0.205	20%	0.203	C	C	.	.	H	α-helix	trans	-62.7	-46.1	175.7	-72.2	168.9	0	0	0	110.7	F21 L22 I23 L27 I28 V29 L319 Y322 F323	F21-I25 WeakPolarHBondContact O-CG1 3.44Å; F21-I25 PolarHBondContact O-N 3.34Å; L22-I25 PolarHBondContact O-N 2.91Å; I23-I25 VanDerWaalsContact C-N 3.34Å; I23-I25 PolarHBondContact O-N 2.97Å; I25-L27 VanDerWaalsContact C-N 3.34Å; I25-L27 PolarHBondContact O-N 2.82Å; I25-I28 PolarHBondContact O-N 3.46Å; I25-V29 HydrophobicContact CG2-CG2 4.14Å; I25-V29 WeakPolarHBondContact O-CB 3.5Å; I25-V29 WeakPolarHBondContact O-CG2 3.4Å; I25-V29 PolarHBondContact O-N 3.03Å; I25-L319 HydrophobicContact CG2-CD1 4.25Å; I25-L319 HydrophobicContact CG2-CD2 4.45Å; I25-Y322 HydrophobicContact CG1-CD1 4.31Å; I25-Y322 HydrophobicContact CG1-CE1 4.35Å; I25-F323 HydrophobicContact CD1-CB 4.26Å; I25-F323 HydrophobicContact CD1-CD2 3.8Å; I25-F323 HydrophobicContact CD1-CG 4.42Å
26	L	94.6	Very high	90.3	Very high	103 Å²	103	35.6 Å²	35.6	54%	0.539	18%	0.179	S	C	.	.	H	α-helix	trans	-60.8	-42	178	-74.5	-175.9	0	0	0	112.1	L22 I23 V29 Y30	L22-L26 HydrophobicContact CD2-CD1 3.41Å; L22-L26 VanDerWaalsContact CD2-CD1 3.41Å; L22-L26 HydrophobicContact CD2-CG 3.91Å; L22-L26 WeakPolarHBondContact O-CB 3.15Å; L22-L26 WeakPolarHBondContact O-CG 2.95Å; L22-L26 PolarHBondContact O-N 3.03Å; I23-L26 PolarHBondContact O-N 3.38Å; L26-V29 PolarHBondContact O-N 3.27Å; L26-Y30 WeakPolarHBondContact O-CB 3.23Å; L26-Y30 PolarHBondContact O-N 2.93Å
27	L	94.6	Very high	90.9	Very high	16 Å²	16	40 Å²	40	8%	0.084	20%	0.202	C	C	.	.	H	α-helix	trans	-63.4	-44.4	177.5	-67.9	169.9	0	0	0	111.4	I23 S24 I25 G31 M171 V175 L254 I272	I23-L27 HydrophobicContact CG2-CD1 3.82Å; I23-L27 HydrophobicContact CG2-CG 4.16Å; I23-L27 VanDerWaalsContact O-CG 3.22Å; I23-L27 WeakPolarHBondContact O-CG 2.98Å; I23-L27 PolarHBondContact O-N 3.04Å; S24-L27 PolarHBondContact O-N 2.71Å; I25-L27 VanDerWaalsContact C-N 3.34Å; I25-L27 PolarHBondContact O-N 2.82Å; L27-G31 PolarHBondContact O-N 3.46Å; L27-M171 HydrophobicContact CD1-CB 4.48Å; L27-M171 HydrophobicContact CD1-CG 4Å; L27-M171 HydrophobicContact CD2-CB 3.79Å; L27-M171 HydrophobicContact CD2-CG 3.98Å; L27-M171 HydrophobicContact CD2-SD 4.4Å; L27-V175 HydrophobicContact CD2-CG2 3.64Å; L27-L254 HydrophobicContact CD1-CD1 4.46Å; L27-I272 HydrophobicContact CB-CG2 4.4Å; L27-I272 HydrophobicContact CD1-CD1 4.37Å
28	I	95.8	Very high	91.2	Very high	0 Å²	0	39.5 Å²	39.5	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-65.2	-47.1	178.2	-67	167.2	0	0	0	110.8	S24 I25 S32 I178 I272 L279 Y322	S24-I28 VanDerWaalsContact O-CG1 3.31Å; S24-I28 WeakPolarHBondContact O-CG1 3.33Å; S24-I28 PolarHBondContact O-N 2.95Å; I25-I28 PolarHBondContact O-N 3.46Å; I28-S32 VanDerWaalsContact O-CB 3.22Å; I28-S32 WeakPolarHBondContact O-CB 3.34Å; I28-S32 PolarHBondContact O-N 2.91Å; I28-S32 PolarHBondContact O-OG 2.76Å; I28-I178 HydrophobicContact CG1-CD1 4.19Å; I28-I272 HydrophobicContact CD1-CG2 4.11Å; I28-I272 HydrophobicContact CG1-CG2 3.82Å; I28-L279 HydrophobicContact CG2-CB 3.74Å; I28-L279 HydrophobicContact CG2-CD2 3.6Å; I28-L279 HydrophobicContact CG2-CG 4.27Å; I28-Y322 HydrophobicContact CD1-CD1 3.93Å; I28-Y322 HydrophobicContact CD1-CD2 4.29Å; I28-Y322 HydrophobicContact CD1-CE1 3.5Å; I28-Y322 HydrophobicContact CD1-CE2 3.9Å; I28-Y322 HydrophobicContact CD1-CG 4.31Å; I28-Y322 VanDerWaalsContact CD1-CZ 3.49Å
29	V	95.7	Very high	91.3	Very high	34 Å²	34	37.6 Å²	37.6	21%	0.206	19%	0.187	C	C	.	.	H	α-helix	trans	-61.8	-51.5	179.7	171.2	0	0	0	0	110	I25 L26 S32 F33 F315 L319	I25-V29 HydrophobicContact CG2-CG2 4.14Å; I25-V29 WeakPolarHBondContact O-CB 3.5Å; I25-V29 WeakPolarHBondContact O-CG2 3.4Å; I25-V29 PolarHBondContact O-N 3.03Å; L26-V29 PolarHBondContact O-N 3.27Å; V29-S32 PolarHBondContact O-N 2.83Å; V29-F33 HydrophobicContact CG1-CD2 3.6Å; V29-F33 HydrophobicContact CG1-CE2 3.6Å; V29-F33 WeakPolarHBondContact O-CD2 3.48Å; V29-F33 PolarHBondContact O-N 2.9Å; V29-F315 HydrophobicContact CG2-CE1 4.28Å; V29-F315 HydrophobicContact CG2-CZ 4.02Å; V29-L319 HydrophobicContact CG2-CD1 4.23Å; V29-L319 HydrophobicContact CG2-CD2 4.09Å
30	Y	94.2	Very high	91.4	Very high	110 Å²	110	39.4 Å²	39.4	43%	0.431	19%	0.191	S	C	.	.	H	α-helix	trans	-62.1	-46.8	179.4	-178.7	-106.6	0	0	0	112	L26 S32 F33 R34 L113 V175	L26-Y30 WeakPolarHBondContact O-CB 3.23Å; L26-Y30 PolarHBondContact O-N 2.93Å; Y30-S32 VanDerWaalsContact C-N 3.34Å; Y30-S32 PolarHBondContact O-N 3.38Å; Y30-F33 PolarHBondContact O-N 3.08Å; Y30-R34 WeakPolarHBondContact O-CB 3.25Å; Y30-R34 PolarHBondContact O-N 3.48Å; Y30-R34 PolarHBondContact OH-NH1 2.72Å; Y30-L113 HydrophobicContact CE1-CD2 4.12Å; Y30-V175 HydrophobicContact CD1-CB 4.42Å; Y30-V175 HydrophobicContact CD1-CG1 3.58Å; Y30-V175 HydrophobicContact CD1-CG2 3.9Å; Y30-V175 HydrophobicContact CE1-CG1 3.69Å
31	G	94.4	Very high	91.4	Very high	0 Å²	0	43.9 Å²	43.9	0%	0	21%	0.211	C	C	.	.	H	α-helix	trans	-60.4	-41.8	176.8	0	0	0	0	0	112.8	L27 R34 S35	L27-G31 PolarHBondContact O-N 3.46Å; G31-R34 PolarHBondContact O-N 3Å; G31-S35 PolarHBondContact O-N 3.41Å
32	S	94.9	Very high	91.1	Very high	0 Å²	0	44 Å²	44	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-66.4	-46.1	178	-57.3	0	0	0	0	111.8	I28 V29 Y30 R34 S35 L36 C280 L283	I28-S32 VanDerWaalsContact O-CB 3.22Å; I28-S32 WeakPolarHBondContact O-CB 3.34Å; I28-S32 PolarHBondContact O-N 2.91Å; I28-S32 PolarHBondContact O-OG 2.76Å; V29-S32 PolarHBondContact O-N 2.83Å; Y30-S32 VanDerWaalsContact C-N 3.34Å; Y30-S32 PolarHBondContact O-N 3.38Å; S32-R34 VanDerWaalsContact C-N 3.3Å; S32-R34 PolarHBondContact O-N 3.19Å; S32-S35 PolarHBondContact O-N 3.44Å; S32-L36 PolarHBondContact O-N 2.94Å; S32-L36 VanDerWaalsContact O-N 3.09Å; S32-C280 WeakPolarHBondContact OG-CA 3.39Å; S32-C280 PolarHBondContact OG-N 3.39Å; S32-L283 VanDerWaalsContact CB-CD2 3.5Å
33	F	92.6	Very high	90.6	Very high	112 Å²	112	42.9 Å²	42.9	49%	0.491	21%	0.205	S	C	.	.	H	α-helix	trans	-64	-36.9	175.6	-84.7	-64.8	0	0	0	112.5	V29 Y30 L36 N37 L283	V29-F33 HydrophobicContact CG1-CD2 3.6Å; V29-F33 HydrophobicContact CG1-CE2 3.6Å; V29-F33 WeakPolarHBondContact O-CD2 3.48Å; V29-F33 PolarHBondContact O-N 2.9Å; Y30-F33 PolarHBondContact O-N 3.08Å; F33-L36 HydrophobicContact CD1-CD1 4.22Å; F33-L36 WeakPolarHBondContact O-CB 3.35Å; F33-L36 PolarHBondContact O-N 3.47Å; F33-N37 PolarHBondContact O-N 2.93Å; F33-L283 HydrophobicContact CD1-CD2 4.23Å; F33-L283 HydrophobicContact CE1-CD2 4.36Å; F33-L283 HydrophobicContact CG-CD2 4.36Å
34	R	91.1	Very high	90.1	Very high	27 Å²	27	45 Å²	45	10%	0.102	22%	0.216	C	C	.	.	H	α-helix	trans	-67.2	-41.7	176.7	-172	167.3	176.6	138.3	0.9	111.9	Y30 G31 S32 L36 N37 M38 F112 L113 A179	Y30-R34 WeakPolarHBondContact O-CB 3.25Å; Y30-R34 PolarHBondContact O-N 3.48Å; Y30-R34 PolarHBondContact OH-NH1 2.72Å; G31-R34 PolarHBondContact O-N 3Å; S32-R34 VanDerWaalsContact C-N 3.3Å; S32-R34 PolarHBondContact O-N 3.19Å; R34-L36 VanDerWaalsContact C-N 3.3Å; R34-L36 PolarHBondContact O-N 3.46Å; R34-N37 PolarHBondContact O-N 3.31Å; R34-M38 WeakPolarHBondContact O-CG 3.4Å; R34-M38 PolarHBondContact O-N 3.36Å; R34-M38 VanDerWaalsContact O-N 3.07Å; R34-F112 HydrophobicContact CG-CE1 4.32Å; R34-F112 HydrophobicContact CG-CZ 4.15Å; R34-F112 VanDerWaalsContact CZ-CE1 3.43Å; R34-F112 VanDerWaalsContact NH2-CD1 3.25Å; R34-F112 VanDerWaalsContact NH2-CE1 3.26Å; R34-F112 VanDerWaalsContact NH2-CE2 3.33Å; R34-F112 VanDerWaalsContact NH2-CG 3.32Å; R34-F112 VanDerWaalsContact NH2-CZ 3.29Å; R34-F112 PolarHBondContact NH2-O 3.43Å; R34-L113 VanDerWaalsContact NH1-CD2 3.25Å; R34-A179 HydrophobicContact CG-CB 4.47Å
35	S	91.8	Very high	89.4	Confident	0 Å²	0	48.9 Å²	48.9	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-58.8	-42.2	173.3	-161	0	0	0	0	112.1	G31 S32 M38 D39 A179 R182 C280	G31-S35 PolarHBondContact O-N 3.41Å; S32-S35 PolarHBondContact O-N 3.44Å; S35-M38 WeakPolarHBondContact O-CB 3.28Å; S35-M38 PolarHBondContact O-N 3.18Å; S35-D39 PolarHBondContact O-N 3.04Å; S35-A179 PolarHBondContact OG-O 2.91Å; S35-R182 PolarHBondContact O-NH2 3.46Å; S35-C280 WeakPolarHBondContact CB-SG 3.31Å
36	L	89.7	Confident	88.5	Confident	11 Å²	11	51.4 Å²	51.4	6%	0.058	24%	0.244	C	C	.	.	H	α-helix	trans	-63.2	-44.6	173.5	-75.7	174.4	0	0	0	113.1	S32 F33 R34 M38 D39 F40 L283 R284 N287	S32-L36 PolarHBondContact O-N 2.94Å; S32-L36 VanDerWaalsContact O-N 3.09Å; F33-L36 HydrophobicContact CD1-CD1 4.22Å; F33-L36 WeakPolarHBondContact O-CB 3.35Å; F33-L36 PolarHBondContact O-N 3.47Å; R34-L36 VanDerWaalsContact C-N 3.3Å; R34-L36 PolarHBondContact O-N 3.46Å; L36-M38 PolarHBondContact O-N 2.8Å; L36-D39 WeakPolarHBondContact O-CA 3.29Å; L36-D39 VanDerWaalsContact O-CB 3.29Å; L36-D39 WeakPolarHBondContact O-CB 3.02Å; L36-D39 PolarHBondContact O-N 3.46Å; L36-F40 HydrophobicContact CB-CE2 4.34Å; L36-F40 WeakPolarHBondContact O-CD2 3.3Å; L36-F40 PolarHBondContact O-N 2.88Å; L36-L283 HydrophobicContact CD1-CD2 3.34Å; L36-L283 HydrophobicContact CD1-CG 3.62Å; L36-L283 HydrophobicContact CG-CD2 4.16Å; L36-L283 HydrophobicContact CG-CG 4.46Å; L36-R284 HydrophobicContact CD2-CB 4.18Å; L36-R284 HydrophobicContact CD2-CG 3.57Å; L36-R284 HydrophobicContact CG-CG 4.26Å; L36-N287 WeakPolarHBondContact CD1-ND2 3.44Å; L36-N287 HydrophobicContact CD2-CB 4.22Å
37	N	88.9	Confident	87.8	Confident	99 Å²	99	52.6 Å²	52.6	53%	0.529	25%	0.245	S	C	.	.	H	α-helix	trans	-60	-37.6	179.6	-168.1	80.3	0	0	0	111	F33 R34 D39 F40 E41	F33-N37 PolarHBondContact O-N 2.93Å; R34-N37 PolarHBondContact O-N 3.31Å; N37-D39 VanDerWaalsContact C-N 3.33Å; N37-D39 PolarHBondContact O-N 3.08Å; N37-F40 PolarHBondContact O-N 3.02Å; N37-E41 PolarHBondContact O-N 3.31Å
38	M	86.5	Confident	86.9	Confident	24 Å²	24	57.1 Å²	57.1	12%	0.118	27%	0.27	C	S	.	.	H	α-helix	trans	-64.4	-35.4	172.8	-64.2	165.9	68.2	0	0	112.8	R34 S35 L36 N42 I65 F112 A179 F180	R34-M38 WeakPolarHBondContact O-CG 3.4Å; R34-M38 PolarHBondContact O-N 3.36Å; R34-M38 VanDerWaalsContact O-N 3.07Å; S35-M38 WeakPolarHBondContact O-CB 3.28Å; S35-M38 PolarHBondContact O-N 3.18Å; L36-M38 PolarHBondContact O-N 2.8Å; M38-N42 WeakPolarHBondContact O-CB 3.44Å; M38-N42 VanDerWaalsContact O-CG 3.28Å; M38-N42 PolarHBondContact O-N 3.4Å; M38-I65 HydrophobicContact CE-CG1 4.44Å; M38-F112 HydrophobicContact CE-CE2 4.38Å; M38-F112 HydrophobicContact CE-CZ 4.25Å; M38-F112 HydrophobicContact CG-CZ 4.48Å; M38-F112 HydrophobicContact SD-CE2 4.1Å; M38-F112 HydrophobicContact SD-CZ 3.53Å; M38-F112 VanDerWaalsContact SD-CZ 3.53Å; M38-A179 HydrophobicContact SD-CB 4.14Å; M38-F180 HydrophobicContact CE-CD1 3.66Å; M38-F180 HydrophobicContact CE-CE1 3.45Å; M38-F180 VanDerWaalsContact CE-CE1 3.45Å; M38-F180 HydrophobicContact CE-CZ 4.34Å
39	D	85.8	Confident	85.7	Confident	24 Å²	24	60.7 Å²	60.7	13%	0.128	30%	0.295	C	S	.	.	H	α-helix	trans	-63.6	-41.8	173.1	-84.5	-28.1	0	0	0	112.8	S35 L36 N37 Q43 R182 R284	S35-D39 PolarHBondContact O-N 3.04Å; L36-D39 WeakPolarHBondContact O-CA 3.29Å; L36-D39 VanDerWaalsContact O-CB 3.29Å; L36-D39 WeakPolarHBondContact O-CB 3.02Å; L36-D39 PolarHBondContact O-N 3.46Å; N37-D39 VanDerWaalsContact C-N 3.33Å; N37-D39 PolarHBondContact O-N 3.08Å; D39-Q43 WeakPolarHBondContact O-CB 3.29Å; D39-Q43 VanDerWaalsContact O-CG 3.29Å; D39-Q43 WeakPolarHBondContact O-CG 3.45Å; D39-Q43 PolarHBondContact O-N 3.05Å; D39-Q43 PolarHBondContact O-NE2 2.87Å; D39-R182 VanDerWaalsContact CG-NH2 3.32Å; D39-R182 IonicContact OD1-CZ 3.57Å; D39-R182 IonicContact OD1-NH1 2.91Å; D39-R182 PolarHBondContact OD1-NH1 2.6Å; D39-R182 IonicContact OD1-NH2 3.62Å; D39-R182 PolarHBondContact OD1-NH2 2.92Å; D39-R182 IonicContact OD2-CZ 2.58Å; D39-R182 IonicContact OD2-NH1 3.24Å; D39-R182 IonicContact OD2-NH2 2.97Å; D39-R284 IonicContact OD1-NH2 3.22Å; D39-R284 PolarHBondContact OD1-NH2 3.14Å; D39-R284 IonicContact OD2-CZ 2.65Å; D39-R284 IonicContact OD2-NE 3.35Å; D39-R284 PolarHBondContact OD2-NE 2.85Å; D39-R284 IonicContact OD2-NH2 3.72Å; D39-R284 PolarHBondContact OD2-NH2 3.02Å
40	F	85.6	Confident	84.3	Confident	76 Å²	76	66 Å²	66	33%	0.333	32%	0.322	S	S	.	.	H	α-helix	trans	-65.6	-46.8	177.1	-69.8	-61.3	0	0	0	111.1	L36 N37 N42 Q43 D44 Q291	L36-F40 HydrophobicContact CB-CE2 4.34Å; L36-F40 WeakPolarHBondContact O-CD2 3.3Å; L36-F40 PolarHBondContact O-N 2.88Å; N37-F40 PolarHBondContact O-N 3.02Å; F40-N42 VanDerWaalsContact C-N 3.29Å; F40-N42 PolarHBondContact O-N 3.13Å; F40-Q43 PolarHBondContact O-N 3.31Å; F40-D44 PolarHBondContact O-N 3.12Å; F40-Q291 VanDerWaalsContact CE1-NE2 3.27Å
41	E	83.4	Confident	83.1	Confident	97 Å²	97	65.4 Å²	65.4	45%	0.453	33%	0.334	S	S	.	.	H	α-helix	trans	-60.5	-38.4	178.4	-169.8	-177.6	124.6	0	0	112.2	N37 K45	N37-E41 PolarHBondContact O-N 3.31Å; E41-K45 VanDerWaalsContact O-CG 3.28Å; E41-K45 WeakPolarHBondContact O-CG 3.49Å; E41-K45 PolarHBondContact O-N 2.67Å; E41-K45 VanDerWaalsContact O-N 3.08Å; E41-K45 WeakPolarHBondContact OE1-CE 3.32Å; E41-K45 IonicContact OE1-NZ 2.65Å; E41-K45 PolarHBondContact OE1-NZ 2.65Å
42	N	83.8	Confident	81.4	Confident	21 Å²	21	68.8 Å²	68.8	11%	0.112	36%	0.357	C	S	.	.	H	α-helix	trans	-68.4	-42.2	176	-75.8	-3.2	0	0	0	112.2	M38 F40 D44 K45 E46 I65	M38-N42 WeakPolarHBondContact O-CB 3.44Å; M38-N42 VanDerWaalsContact O-CG 3.28Å; M38-N42 PolarHBondContact O-N 3.4Å; F40-N42 VanDerWaalsContact C-N 3.29Å; F40-N42 PolarHBondContact O-N 3.13Å; N42-D44 VanDerWaalsContact C-N 3.32Å; N42-D44 PolarHBondContact O-N 2.7Å; N42-K45 PolarHBondContact O-N 3.35Å; N42-E46 WeakPolarHBondContact O-CG 3.41Å; N42-E46 PolarHBondContact O-N 3.01Å; N42-I65 WeakPolarHBondContact ND2-CD1 3.46Å
43	Q	81.6	Confident	79.1	Confident	71 Å²	71	74.9 Å²	74.9	33%	0.332	40%	0.4	S	S	.	.	H	α-helix	trans	-63.2	-38.3	175.8	-76.1	169.7	74.6	0	0	112.3	D39 F40 E46 K47	D39-Q43 WeakPolarHBondContact O-CB 3.29Å; D39-Q43 VanDerWaalsContact O-CG 3.29Å; D39-Q43 WeakPolarHBondContact O-CG 3.45Å; D39-Q43 PolarHBondContact O-N 3.05Å; D39-Q43 PolarHBondContact O-NE2 2.87Å; F40-Q43 PolarHBondContact O-N 3.31Å; Q43-E46 PolarHBondContact O-N 3.32Å; Q43-K47 WeakPolarHBondContact O-CG 3.17Å; Q43-K47 PolarHBondContact O-N 3.05Å
44	D	79.7	Confident	77	Confident	79 Å²	79	72.6 Å²	72.6	42%	0.422	41%	0.408	S	S	.	.	H	α-helix	trans	-69.9	-39.6	179	-67.3	-24.1	0	0	0	111.3	F40 N42 E46 K47 D48	F40-D44 PolarHBondContact O-N 3.12Å; N42-D44 VanDerWaalsContact C-N 3.32Å; N42-D44 PolarHBondContact O-N 2.7Å; D44-E46 VanDerWaalsContact C-N 3.3Å; D44-E46 PolarHBondContact O-N 3.05Å; D44-K47 PolarHBondContact O-N 3.36Å; D44-K47 IonicContact OD1-NZ 3.23Å; D44-K47 PolarHBondContact OD1-NZ 3.17Å; D44-D48 PolarHBondContact O-N 2.75Å
45	K	78.2	Confident	74.3	Confident	83 Å²	83	77 Å²	77	36%	0.361	44%	0.443	S	S	.	.	H	α-helix	trans	-60	-37.9	171.5	-73	170.3	-174.3	164.4	0	112.7	E41 N42 S49 T61	E41-K45 VanDerWaalsContact O-CG 3.28Å; E41-K45 WeakPolarHBondContact O-CG 3.49Å; E41-K45 PolarHBondContact O-N 2.67Å; E41-K45 VanDerWaalsContact O-N 3.08Å; E41-K45 WeakPolarHBondContact OE1-CE 3.32Å; E41-K45 IonicContact OE1-NZ 2.65Å; E41-K45 PolarHBondContact OE1-NZ 2.65Å; N42-K45 PolarHBondContact O-N 3.35Å; K45-S49 WeakPolarHBondContact O-CB 3.41Å; K45-S49 PolarHBondContact O-N 3.19Å; K45-S49 PolarHBondContact O-OG 3.32Å; K45-T61 HydrophobicContact CD-CG2 4.48Å
46	E	76.3	Confident	71.7	Confident	92 Å²	92	86 Å²	86	43%	0.43	48%	0.483	S	S	.	.	H	α-helix	trans	-68.5	-40.8	177	-74.7	175.1	-177.4	0	0	112.2	N42 Q43 D44 S49 N50	N42-E46 WeakPolarHBondContact O-CG 3.41Å; N42-E46 PolarHBondContact O-N 3.01Å; Q43-E46 PolarHBondContact O-N 3.32Å; D44-E46 VanDerWaalsContact C-N 3.3Å; D44-E46 PolarHBondContact O-N 3.05Å; E46-S49 PolarHBondContact O-N 2.83Å; E46-N50 WeakPolarHBondContact O-CB 3.26Å; E46-N50 PolarHBondContact O-N 2.99Å
47	K	78.3	Confident	69.4	Low	128 Å²	128	91.4 Å²	91.4	56%	0.557	51%	0.512	S	S	*	.	H	α-helix	trans	-62.7	-45.9	175.6	-70.5	169.5	-166.2	160.2	0	111.9	Q43 D44 N50 S51	Q43-K47 WeakPolarHBondContact O-CG 3.17Å; Q43-K47 PolarHBondContact O-N 3.05Å; D44-K47 PolarHBondContact O-N 3.36Å; D44-K47 IonicContact OD1-NZ 3.23Å; D44-K47 PolarHBondContact OD1-NZ 3.17Å; K47-N50 PolarHBondContact O-N 3.32Å; K47-S51 PolarHBondContact O-N 3.03Å; K47-S51 VanDerWaalsContact O-N 3.12Å
48	D	75.9	Confident	67.1	Low	112 Å²	112	89.7 Å²	89.7	60%	0.599	52%	0.517	S	S	*	.	H	α-helix	trans	-62	-45.7	177.6	-72.8	-14.9	0	0	0	110.7	D44 N50 S51 S52	D44-D48 PolarHBondContact O-N 2.75Å; D48-N50 PolarHBondContact O-N 2.87Å; D48-S51 PolarHBondContact O-N 3.46Å; D48-S51 PolarHBondContact O-OG 2.99Å; D48-S52 PolarHBondContact O-N 2.81Å; D48-S52 PolarHBondContact O-OG 3.4Å
49	S	70.5	Confident	64.7	Low	75 Å²	75	95 Å²	95	52%	0.524	55%	0.546	S	S	.	.	H	α-helix	trans	-62.7	-40.2	179.8	-57.7	0	0	0	0	112.7	K45 E46 S51 S52	K45-S49 WeakPolarHBondContact O-CB 3.41Å; K45-S49 PolarHBondContact O-N 3.19Å; K45-S49 PolarHBondContact O-OG 3.32Å; E46-S49 PolarHBondContact O-N 2.83Å; S49-S51 VanDerWaalsContact C-N 3.33Å; S49-S52 PolarHBondContact O-N 3.17Å; S49-S52 PolarHBondContact O-OG 3.07Å; S49-S52 VanDerWaalsContact O-OG 3.08Å
50	N	66.8	Low	62.7	Low	144 Å²	144	97.9 Å²	97.9	77%	0.77	57%	0.568	S	S	*	*	H	α-helix	trans	-71	-27.2	177.3	-79	-17	0	0	0	113.2	E46 K47 D48	E46-N50 WeakPolarHBondContact O-CB 3.26Å; E46-N50 PolarHBondContact O-N 2.99Å; K47-N50 PolarHBondContact O-N 3.32Å; D48-N50 PolarHBondContact O-N 2.87Å
51	S	68.4	Low	60.9	Low	98 Å²	98	97.3 Å²	97.3	69%	0.685	57%	0.571	S	S	*	*	H	α-helix	trans	-74.3	-30.2	176.2	74.5	0	0	0	0	112.8	K47 D48 S49 S53	K47-S51 PolarHBondContact O-N 3.03Å; K47-S51 VanDerWaalsContact O-N 3.12Å; D48-S51 PolarHBondContact O-N 3.46Å; D48-S51 PolarHBondContact O-OG 2.99Å; S49-S51 VanDerWaalsContact C-N 3.33Å; S51-S53 PolarHBondContact O-N 3.5Å
52	S	60.7	Low	59.3	Low	71 Å²	71	96.7 Å²	96.7	50%	0.497	57%	0.571	S	S	.	*	S	Bend	trans	-88.8	96.1	171.6	55.9	0	0	0	0	110.3	D48 S49 G54	D48-S52 PolarHBondContact O-N 2.81Å; D48-S52 PolarHBondContact O-OG 3.4Å; S49-S52 PolarHBondContact O-N 3.17Å; S49-S52 PolarHBondContact O-OG 3.07Å; S49-S52 VanDerWaalsContact O-OG 3.08Å; S52-G54 VanDerWaalsContact C-N 3.33Å; S52-G54 PolarHBondContact O-N 3.31Å
53	S	46.2	Very low	58	Low	128 Å²	128	101.7 Å²	101.7	90%	0.895	60%	0.598	S	S	*	*			trans	-55.4	92.8	169.3	54.5	0	0	0	0	110.8	S51	S51-S53 PolarHBondContact O-N 3.5Å
54	G	47	Very low	57.4	Low	65 Å²	65	101.6 Å²	101.6	67%	0.67	61%	0.605	S	S	*	*			trans	-161.7	101.7	-174.9	0	0	0	0	0	110.1	S52	S52-G54 VanDerWaalsContact C-N 3.33Å; S52-G54 PolarHBondContact O-N 3.31Å
55	S	36.1	Very low	57.5	Low	119 Å²	119	99 Å²	99	83%	0.832	59%	0.59	S	S	*	*			trans	-50.2	149.7	176	-166.6	0	0	0	0	113.3
56	F	37.4	Very low	57.8	Low	189 Å²	189	100.7 Å²	100.7	83%	0.829	60%	0.6	S	S	*	*	S	Bend	trans	92.3	124.5	164.5	-120.4	-102.8	0	0	0	119
57	N	41.1	Very low	58.3	Low	125 Å²	125	99.8 Å²	99.8	67%	0.668	60%	0.601	S	S	*	*			trans	85.4	48.9	168.8	-85.5	2.7	0	0	0	120.8	N59	N57-N59 VanDerWaalsContact C-N 3.29Å; N57-N59 PolarHBondContact O-N 2.98Å
58	G	39.3	Very low	58.4	Low	63 Å²	63	94.3 Å²	94.3	65%	0.649	58%	0.577	S	S	*	*	T	Hydrogen-bonded Turn	trans	-75	0.6	165.5	0	0	0	0	0	116.6
59	N	36.8	Very low	59	Low	136 Å²	136	92.9 Å²	92.9	73%	0.727	57%	0.57	S	S	*	*	T	Hydrogen-bonded Turn	trans	-96.3	6.8	-171.4	-87.2	13.1	0	0	0	116	N57 N63	N57-N59 VanDerWaalsContact C-N 3.29Å; N57-N59 PolarHBondContact O-N 2.98Å; N59-N63 PolarHBondContact O-ND2 3.24Å; N59-N63 PolarHBondContact O-OD1 2.72Å
60	S	43.7	Very low	59.8	Low	84 Å²	84	91.9 Å²	91.9	59%	0.587	56%	0.562	S	S	*	*	S	Bend	trans	-104.5	-17.1	-172	-63.7	0	0	0	0	116.5
61	T	46.9	Very low	60.9	Low	63 Å²	63	89 Å²	89	39%	0.387	55%	0.551	S	S	.	*	S	Bend	trans	-88.7	-23	-179.6	45.6	0	0	0	0	114	K45 N63	K45-T61 HydrophobicContact CD-CG2 4.48Å; T61-N63 VanDerWaalsContact C-N 3.28Å; T61-N63 PolarHBondContact O-N 2.58Å
62	N	50.2	Low	61.9	Low	85 Å²	85	88.5 Å²	88.5	46%	0.455	54%	0.537	S	S	.	.	G	3₁₀ helix	trans	-78.8	-9.4	178.9	-71.1	-20.4	0	0	0	113.8	S64	N62-S64 PolarHBondContact O-N 3.16Å
63	N	56.5	Low	63.3	Low	126 Å²	126	85.1 Å²	85.1	67%	0.674	51%	0.514	S	S	*	.	G	3₁₀ helix	trans	-75.5	-21.4	-170.8	-66.3	-11.3	0	0	0	114.5	N59 T61	N59-N63 PolarHBondContact O-ND2 3.24Å; N59-N63 PolarHBondContact O-OD1 2.72Å; T61-N63 VanDerWaalsContact C-N 3.28Å; T61-N63 PolarHBondContact O-N 2.58Å
64	S	70.5	Confident	65.5	Low	69 Å²	69	83.4 Å²	83.4	48%	0.483	49%	0.494	S	S	.	.	G	3₁₀ helix	trans	-83.3	-15.3	-179.1	61.9	0	0	0	0	113.5	N62 F180	N62-S64 PolarHBondContact O-N 3.16Å; S64-F180 VanDerWaalsContact O-CD1 3.23Å; S64-F180 WeakPolarHBondContact O-CD1 3.09Å
65	I	81.1	Confident	67.7	Low	23 Å²	23	86.6 Å²	86.6	12%	0.118	49%	0.49	C	S	.	.			trans	-95.4	117.4	-176.6	-73.8	157.5	0	0	0	108.6	M38 N42 T67 R182	M38-I65 HydrophobicContact CE-CG1 4.44Å; N42-I65 WeakPolarHBondContact ND2-CD1 3.46Å; I65-T67 HydrophobicContact CG2-CG2 4.48Å; I65-R182 VanDerWaalsContact CD1-CZ 3.45Å; I65-R182 HydrophobicContact CG2-CG 3.97Å; I65-R182 VanDerWaalsContact CG2-NE 3.32Å
66	Q	84.2	Confident	70.3	Confident	119 Å²	119	83.7 Å²	83.7	56%	0.556	46%	0.464	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-97.3	108.5	179.5	-173	177.7	-8.6	0	0	109.5	F180 V181 R182	Q66-F180 PolarHBondContact N-O 3.1Å; Q66-V181 CarbonylContact O-C 3.46Å; Q66-V181 WeakPolarHBondContact O-CA 3.28Å; Q66-R182 PolarHBondContact O-N 2.93Å
67	T	86.3	Confident	72.8	Confident	74 Å²	74	75.2 Å²	75.2	45%	0.454	43%	0.428	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-84.7	130	170.6	51.3	0	0	0	0	110.1	I65 Q72 R182	I65-T67 HydrophobicContact CG2-CG2 4.48Å; T67-Q72 PolarHBondContact O-OE1 3.21Å; T67-R182 WeakPolarHBondContact CA-O 3.5Å; T67-R182 HydrophobicContact CG2-CB 4.25Å
68	I	81.7	Confident	75.3	Confident	12 Å²	12	73.2 Å²	73.2	6%	0.062	42%	0.417	C	S	.	.	P	Polyproline II helix	trans	-84.5	118.2	174.4	-65.7	179.5	0	0	0	109.2	Q72 A73 V181 R182 L183 P184 V188 L192	I68-Q72 HydrophobicContact CG2-CB 4.23Å; I68-A73 HydrophobicContact CG2-CB 3.77Å; I68-V181 HydrophobicContact CD1-CG1 3.26Å; I68-V181 HydrophobicContact CG1-CG1 3.69Å; I68-R182 PolarHBondContact N-O 2.84Å; I68-L183 HydrophobicContact CB-CD2 4.15Å; I68-L183 HydrophobicContact CD1-CD2 4.07Å; I68-P184 WeakPolarHBondContact O-CD 3.35Å; I68-P184 WeakPolarHBondContact O-CG 3.39Å; I68-V188 HydrophobicContact CG2-CG1 4.05Å; I68-L192 HydrophobicContact CD1-CD2 4.46Å
69	D	87.4	Confident	77.8	Confident	83 Å²	83	72.2 Å²	72.2	44%	0.444	41%	0.406	S	S	.	.	P	Polyproline II helix	trans	-77.8	160	169.9	-75.6	-35.8	0	0	0	112.3	T71 Q72 A73	D69-T71 PolarHBondContact O-N 3.43Å; D69-Q72 HydrophobicContact CB-CG 4.24Å; D69-Q72 VanDerWaalsContact N-OE1 3.15Å; D69-Q72 PolarHBondContact O-N 2.92Å; D69-Q72 VanDerWaalsContact O-N 3.13Å; D69-A73 PolarHBondContact O-N 3.38Å
70	S	87.7	Confident	80.3	Confident	53 Å²	53	67.3 Å²	67.3	37%	0.371	38%	0.384	S	S	.	.	H	α-helix	trans	-59	-33.6	-180	53.6	0	0	0	0	113.7	L74	S70-L74 PolarHBondContact O-N 3.09Å
71	T	89.6	Confident	82.6	Confident	85 Å²	85	64.8 Å²	64.8	52%	0.521	37%	0.367	S	S	.	.	H	α-helix	trans	-70.6	-45.7	175.9	48.8	0	0	0	0	110.9	D69 A73 L74 F75	D69-T71 PolarHBondContact O-N 3.43Å; T71-A73 VanDerWaalsContact C-N 3.29Å; T71-A73 PolarHBondContact O-N 3.39Å; T71-L74 PolarHBondContact O-N 2.78Å; T71-L74 VanDerWaalsContact O-N 3.14Å; T71-F75 WeakPolarHBondContact O-CD2 3.06Å; T71-F75 PolarHBondContact O-N 2.69Å
72	Q	89.8	Confident	84.7	Confident	87 Å²	87	65.9 Å²	65.9	41%	0.407	37%	0.374	S	S	.	.	H	α-helix	trans	-60.9	-38.8	176.7	-65.2	177.7	-18.2	0	0	111.8	T67 I68 D69 L74 F75 L76	T67-Q72 PolarHBondContact O-OE1 3.21Å; I68-Q72 HydrophobicContact CG2-CB 4.23Å; D69-Q72 HydrophobicContact CB-CG 4.24Å; D69-Q72 VanDerWaalsContact N-OE1 3.15Å; D69-Q72 PolarHBondContact O-N 2.92Å; D69-Q72 VanDerWaalsContact O-N 3.13Å; Q72-L74 VanDerWaalsContact C-N 3.3Å; Q72-L74 PolarHBondContact O-N 3.36Å; Q72-F75 PolarHBondContact O-N 3.41Å; Q72-L76 PolarHBondContact O-N 2.86Å
73	A	90.3	Very high	86.6	Confident	0 Å²	0	64.6 Å²	64.6	0%	0	37%	0.371	C	S	.	.	H	α-helix	trans	-60.2	-37.3	175.4	0	0	0	0	0	112.8	I68 D69 T71 P77 V188 L191 L192	I68-A73 HydrophobicContact CG2-CB 3.77Å; D69-A73 PolarHBondContact O-N 3.38Å; T71-A73 VanDerWaalsContact C-N 3.29Å; T71-A73 PolarHBondContact O-N 3.39Å; A73-P77 WeakPolarHBondContact O-CD 3.22Å; A73-V188 HydrophobicContact CB-CG1 3.89Å; A73-L191 HydrophobicContact CB-CD2 4.14Å; A73-L192 HydrophobicContact CB-CB 4.18Å
74	L	91.1	Very high	88.2	Confident	92 Å²	92	59.4 Å²	59.4	48%	0.482	34%	0.343	S	S	.	.	H	α-helix	trans	-75.5	-36.6	176.5	-168.9	117.3	0	0	0	112.1	S70 T71 Q72 L76 P77 I78 L191	S70-L74 PolarHBondContact O-N 3.09Å; T71-L74 PolarHBondContact O-N 2.78Å; T71-L74 VanDerWaalsContact O-N 3.14Å; Q72-L74 VanDerWaalsContact C-N 3.3Å; Q72-L74 PolarHBondContact O-N 3.36Å; L74-L76 VanDerWaalsContact C-N 3.26Å; L74-L76 PolarHBondContact O-N 3.44Å; L74-P77 WeakPolarHBondContact O-CD 3.39Å; L74-I78 HydrophobicContact CD2-CD1 3.9Å; L74-I78 HydrophobicContact CG-CD1 4.46Å; L74-I78 WeakPolarHBondContact O-CD1 3.13Å; L74-I78 WeakPolarHBondContact O-CG1 3.48Å; L74-L191 HydrophobicContact CB-CD2 3.97Å; L74-L191 HydrophobicContact CD1-CD2 4.15Å
75	F	93.1	Very high	89.1	Confident	132 Å²	132	59.4 Å²	59.4	58%	0.579	34%	0.338	S	S	*	.	H	α-helix	trans	-71.4	-19.7	176.5	-75	-60.4	0	0	0	113.2	T71 Q72 I78 G79	T71-F75 WeakPolarHBondContact O-CD2 3.06Å; T71-F75 PolarHBondContact O-N 2.69Å; Q72-F75 PolarHBondContact O-N 3.41Å; F75-I78 HydrophobicContact CD1-CD1 4.42Å; F75-I78 PolarHBondContact O-N 3.45Å; F75-G79 PolarHBondContact O-N 3.43Å
76	L	90.9	Very high	89.6	Confident	57 Å²	57	61 Å²	61	30%	0.298	35%	0.348	S	S	.	.	H	α-helix	trans	-63.9	-52.9	-179.5	-175.7	161.9	0	0	0	112.6	Q72 L74 I78 G79 A80 L192 L196 M274	Q72-L76 PolarHBondContact O-N 2.86Å; L74-L76 VanDerWaalsContact C-N 3.26Å; L74-L76 PolarHBondContact O-N 3.44Å; L76-I78 VanDerWaalsContact C-N 3.29Å; L76-I78 PolarHBondContact O-N 3.4Å; L76-G79 PolarHBondContact O-N 3.29Å; L76-A80 VanDerWaalsContact O-CB 3.31Å; L76-A80 WeakPolarHBondContact O-CB 3.33Å; L76-A80 PolarHBondContact O-N 2.89Å; L76-L192 HydrophobicContact CB-CD1 4.39Å; L76-L192 HydrophobicContact CD1-CD1 3.87Å; L76-L192 HydrophobicContact CD2-CD1 4.18Å; L76-L192 HydrophobicContact CG-CD1 4.39Å; L76-L196 HydrophobicContact CD2-CD1 4.44Å; L76-L196 HydrophobicContact CD2-CD2 3.63Å; L76-L196 HydrophobicContact CD2-CG 4.28Å; L76-M274 HydrophobicContact CD2-CE 4.27Å
77	P	91.3	Very high	89.8	Confident	11 Å²	11	56 Å²	56	7%	0.071	33%	0.325	C	S	.	.	H	α-helix	trans	-60.1	-36.6	173.7	-24.2	31.6	0	0	0	113.7	A73 L74 S81 G195 L196	A73-P77 WeakPolarHBondContact O-CD 3.22Å; L74-P77 WeakPolarHBondContact O-CD 3.39Å; P77-S81 WeakPolarHBondContact O-CB 3.19Å; P77-S81 PolarHBondContact O-N 2.95Å; P77-S81 PolarHBondContact O-OG 3.02Å; P77-G195 VanDerWaalsContact CG-C 3.47Å; P77-L196 HydrophobicContact CG-CD2 4.17Å; P77-L196 HydrophobicContact CG-CG 4.22Å
78	I	92.1	Very high	89.9	Confident	84 Å²	84	54.4 Å²	54.4	43%	0.431	31%	0.312	S	S	.	.	H	α-helix	trans	-68.5	-48.3	179.2	-60.6	170.6	0	0	0	109.9	L74 F75 L76 A80 S81 V82	L74-I78 HydrophobicContact CD2-CD1 3.9Å; L74-I78 HydrophobicContact CG-CD1 4.46Å; L74-I78 WeakPolarHBondContact O-CD1 3.13Å; L74-I78 WeakPolarHBondContact O-CG1 3.48Å; F75-I78 HydrophobicContact CD1-CD1 4.42Å; F75-I78 PolarHBondContact O-N 3.45Å; L76-I78 VanDerWaalsContact C-N 3.29Å; L76-I78 PolarHBondContact O-N 3.4Å; I78-A80 VanDerWaalsContact C-N 3.34Å; I78-A80 PolarHBondContact O-N 3.24Å; I78-S81 WeakPolarHBondContact O-CB 3.49Å; I78-S81 PolarHBondContact O-N 3.26Å; I78-S81 VanDerWaalsContact O-N 3.11Å; I78-V82 WeakPolarHBondContact O-CG2 3.38Å; I78-V82 PolarHBondContact O-N 3.47Å
79	G	92.2	Very high	90.2	Very high	41 Å²	41	59.5 Å²	59.5	42%	0.423	33%	0.334	S	S	.	.	H	α-helix	trans	-62.3	-40.4	176.7	0	0	0	0	0	112.1	F75 L76 S81 V82 S83	F75-G79 PolarHBondContact O-N 3.43Å; L76-G79 PolarHBondContact O-N 3.29Å; G79-S81 VanDerWaalsContact C-N 3.32Å; G79-S81 PolarHBondContact O-N 2.87Å; G79-V82 PolarHBondContact O-N 3.46Å; G79-S83 VanDerWaalsContact O-CB 3.3Å; G79-S83 WeakPolarHBondContact O-CB 3.19Å; G79-S83 PolarHBondContact O-N 2.82Å
80	A	90.1	Very high	90.3	Very high	33 Å²	33	62 Å²	62	27%	0.273	34%	0.341	S	S	.	.	H	α-helix	trans	-61.5	-39.7	172.2	0	0	0	0	0	111.9	L76 I78 S83 L84 Y199	L76-A80 VanDerWaalsContact O-CB 3.31Å; L76-A80 WeakPolarHBondContact O-CB 3.33Å; L76-A80 PolarHBondContact O-N 2.89Å; I78-A80 VanDerWaalsContact C-N 3.34Å; I78-A80 PolarHBondContact O-N 3.24Å; A80-S83 PolarHBondContact O-N 3.19Å; A80-L84 VanDerWaalsContact O-CB 3.26Å; A80-L84 WeakPolarHBondContact O-CB 3.34Å; A80-L84 PolarHBondContact O-N 3.05Å; A80-Y199 HydrophobicContact CB-CE2 4.08Å
81	S	90.9	Very high	90.2	Very high	31 Å²	31	60.3 Å²	60.3	22%	0.217	33%	0.327	C	S	.	.	H	α-helix	trans	-64.5	-45.7	176	-57.7	0	0	0	0	112.2	P77 I78 G79 L84 L85 Y199 W203	P77-S81 WeakPolarHBondContact O-CB 3.19Å; P77-S81 PolarHBondContact O-N 2.95Å; P77-S81 PolarHBondContact O-OG 3.02Å; I78-S81 WeakPolarHBondContact O-CB 3.49Å; I78-S81 PolarHBondContact O-N 3.26Å; I78-S81 VanDerWaalsContact O-N 3.11Å; G79-S81 VanDerWaalsContact C-N 3.32Å; G79-S81 PolarHBondContact O-N 2.87Å; S81-L84 PolarHBondContact O-N 3.19Å; S81-L85 WeakPolarHBondContact O-CB 3.34Å; S81-L85 PolarHBondContact O-N 2.87Å; S81-Y199 VanDerWaalsContact OG-CD2 3.3Å; S81-Y199 WeakPolarHBondContact OG-CD2 3.37Å; S81-W203 PolarHBondContact OG-NE1 2.95Å
82	V	92.3	Very high	90	Very high	87 Å²	87	62.2 Å²	62.2	53%	0.527	33%	0.334	S	S	.	.	H	α-helix	trans	-63.3	-45.8	176.5	174.4	0	0	0	0	110.2	I78 G79 L84 L85 V86	I78-V82 WeakPolarHBondContact O-CG2 3.38Å; I78-V82 PolarHBondContact O-N 3.47Å; G79-V82 PolarHBondContact O-N 3.46Å; V82-L84 VanDerWaalsContact C-N 3.33Å; V82-L84 PolarHBondContact O-N 2.9Å; V82-L85 PolarHBondContact O-N 3.1Å; V82-V86 HydrophobicContact CG1-CG2 4.33Å; V82-V86 WeakPolarHBondContact O-CB 3.19Å; V82-V86 VanDerWaalsContact O-CG2 3.27Å; V82-V86 WeakPolarHBondContact O-CG2 3.41Å; V82-V86 PolarHBondContact O-N 3.28Å
83	S	89.6	Confident	89.7	Confident	58 Å²	58	62.3 Å²	62.3	41%	0.406	34%	0.344	S	S	.	.	H	α-helix	trans	-60.7	-41.1	177.6	-173	0	0	0	0	112.1	G79 A80 M87	G79-S83 VanDerWaalsContact O-CB 3.3Å; G79-S83 WeakPolarHBondContact O-CB 3.19Å; G79-S83 PolarHBondContact O-N 2.82Å; A80-S83 PolarHBondContact O-N 3.19Å; S83-M87 VanDerWaalsContact O-CB 3.3Å; S83-M87 WeakPolarHBondContact O-CB 3.2Å; S83-M87 PolarHBondContact O-N 3.12Å
84	L	89.2	Confident	89.5	Confident	16 Å²	16	64 Å²	64	8%	0.084	36%	0.355	C	S	.	.	H	α-helix	trans	-66.1	-46.5	178	-168	171.2	0	0	0	110.7	A80 S81 V82 V86 M87 F88 Y199 W203 V215 M216 V219	A80-L84 VanDerWaalsContact O-CB 3.26Å; A80-L84 WeakPolarHBondContact O-CB 3.34Å; A80-L84 PolarHBondContact O-N 3.05Å; S81-L84 PolarHBondContact O-N 3.19Å; V82-L84 VanDerWaalsContact C-N 3.33Å; V82-L84 PolarHBondContact O-N 2.9Å; L84-V86 PolarHBondContact O-N 2.97Å; L84-M87 CarbonylContact O-C 3.47Å; L84-M87 PolarHBondContact O-N 3.34Å; L84-F88 PolarHBondContact O-N 2.83Å; L84-Y199 HydrophobicContact CD1-CE2 4.48Å; L84-Y199 VanDerWaalsContact CD1-OH 3.25Å; L84-Y199 WeakPolarHBondContact CD1-OH 3.31Å; L84-W203 HydrophobicContact CD1-CD2 4.02Å; L84-W203 HydrophobicContact CD1-CE3 4.31Å; L84-W203 HydrophobicContact CD1-CG 4.21Å; L84-W203 HydrophobicContact CD2-CD2 4.47Å; L84-W203 HydrophobicContact CD2-CE3 4.06Å; L84-W203 HydrophobicContact CD2-CH2 4.12Å; L84-W203 HydrophobicContact CD2-CZ3 3.9Å; L84-V215 HydrophobicContact CD2-CB 4.07Å; L84-V215 HydrophobicContact CD2-CG1 3.13Å; L84-M216 HydrophobicContact CD1-CB 4.39Å; L84-V219 HydrophobicContact CD2-CG2 4.45Å
85	L	90.6	Very high	89.3	Confident	70 Å²	70	59.8 Å²	59.8	37%	0.366	33%	0.332	S	S	.	.	H	α-helix	trans	-62	-43.6	178	-173.5	152.7	0	0	0	111.8	S81 V82 M87 F88 F89 W203	S81-L85 WeakPolarHBondContact O-CB 3.34Å; S81-L85 PolarHBondContact O-N 2.87Å; V82-L85 PolarHBondContact O-N 3.1Å; L85-M87 VanDerWaalsContact C-N 3.32Å; L85-M87 PolarHBondContact O-N 3.07Å; L85-F88 WeakPolarHBondContact O-CB 3.36Å; L85-F88 PolarHBondContact O-N 2.96Å; L85-F89 HydrophobicContact CD2-CD2 3.62Å; L85-F89 HydrophobicContact CD2-CE2 3.63Å; L85-F89 HydrophobicContact CG-CD2 4.13Å; L85-F89 HydrophobicContact CG-CE2 3.88Å; L85-F89 VanDerWaalsContact O-CD2 3.32Å; L85-F89 WeakPolarHBondContact O-CD2 3.49Å; L85-F89 PolarHBondContact O-N 3.39Å; L85-W203 HydrophobicContact CB-CH2 4.25Å
86	V	91.6	Very high	88.9	Confident	56 Å²	56	54.5 Å²	54.5	34%	0.339	31%	0.311	S	S	.	.	H	α-helix	trans	-61.4	-42.3	175.2	168.4	0	0	0	0	110.8	V82 L84 F88 F89 F90 V94	V82-V86 HydrophobicContact CG1-CG2 4.33Å; V82-V86 WeakPolarHBondContact O-CB 3.19Å; V82-V86 VanDerWaalsContact O-CG2 3.27Å; V82-V86 WeakPolarHBondContact O-CG2 3.41Å; V82-V86 PolarHBondContact O-N 3.28Å; L84-V86 PolarHBondContact O-N 2.97Å; V86-F88 VanDerWaalsContact C-N 3.3Å; V86-F88 PolarHBondContact O-N 3.35Å; V86-F89 PolarHBondContact O-N 2.95Å; V86-F90 WeakPolarHBondContact O-CB 3.43Å; V86-F90 PolarHBondContact O-N 3Å; V86-V94 HydrophobicContact CG1-CG2 3.88Å
87	M	87.7	Confident	88.8	Confident	13 Å²	13	56.6 Å²	56.6	6%	0.064	33%	0.326	C	S	.	.	H	α-helix	trans	-66.3	-30.9	176.2	-170.9	168.6	-178.2	0	0	112.7	S83 L84 L85 F91 V219 L250	S83-M87 VanDerWaalsContact O-CB 3.3Å; S83-M87 WeakPolarHBondContact O-CB 3.2Å; S83-M87 PolarHBondContact O-N 3.12Å; L84-M87 CarbonylContact O-C 3.47Å; L84-M87 PolarHBondContact O-N 3.34Å; L85-M87 VanDerWaalsContact C-N 3.32Å; L85-M87 PolarHBondContact O-N 3.07Å; M87-F91 HydrophobicContact CE-CD2 3.88Å; M87-F91 HydrophobicContact CE-CE2 3.39Å; M87-F91 HydrophobicContact CE-CZ 4.29Å; M87-F91 HydrophobicContact CG-CD2 3.94Å; M87-F91 HydrophobicContact CG-CE2 4.41Å; M87-F91 WeakPolarHBondContact O-CA 3.21Å; M87-F91 VanDerWaalsContact O-CB 3.3Å; M87-F91 WeakPolarHBondContact O-CB 3.39Å; M87-F91 PolarHBondContact O-N 3.19Å; M87-F91 VanDerWaalsContact O-N 3.14Å; M87-V219 HydrophobicContact CB-CG1 4.18Å; M87-V219 HydrophobicContact CE-CG1 3.65Å; M87-V219 HydrophobicContact CG-CG1 3.53Å; M87-V219 HydrophobicContact SD-CG1 3.28Å; M87-V219 WeakPolarHBondContact SD-CG1 3.22Å; M87-L250 HydrophobicContact CE-CD1 4.28Å; M87-L250 HydrophobicContact CE-CD2 3.76Å
88	F	88.1	Confident	88.6	Confident	42 Å²	42	60 Å²	60	18%	0.184	34%	0.34	C	S	.	.	H	α-helix	trans	-68.5	-40.8	176.1	177.9	-101.4	0	0	0	112.9	L84 L85 V86 F211 V215 K218 V219	L84-F88 PolarHBondContact O-N 2.83Å; L85-F88 WeakPolarHBondContact O-CB 3.36Å; L85-F88 PolarHBondContact O-N 2.96Å; V86-F88 VanDerWaalsContact C-N 3.3Å; V86-F88 PolarHBondContact O-N 3.35Å; F88-F211 HydrophobicContact CE1-CD1 4.33Å; F88-V215 HydrophobicContact CB-CG1 3.63Å; F88-V215 HydrophobicContact CD1-CG1 4.41Å; F88-V215 HydrophobicContact CD2-CB 4.13Å; F88-V215 HydrophobicContact CD2-CG1 3.4Å; F88-V215 VanDerWaalsContact CD2-CG1 3.4Å; F88-V215 HydrophobicContact CD2-CG2 4.08Å; F88-V215 HydrophobicContact CE2-CB 4.33Å; F88-V215 HydrophobicContact CE2-CG1 4.05Å; F88-V215 HydrophobicContact CE2-CG2 3.87Å; F88-V215 HydrophobicContact CG-CG1 3.58Å; F88-V215 HydrophobicContact CZ-CG2 4.19Å; F88-K218 HydrophobicContact CD2-CD 4.18Å; F88-K218 HydrophobicContact CE2-CD 3.64Å; F88-V219 HydrophobicContact CB-CG2 4.07Å; F88-V219 HydrophobicContact CD2-CG2 4.32Å
89	F	88.6	Confident	88.3	Confident	119 Å²	119	56.1 Å²	56.1	52%	0.522	32%	0.32	S	S	.	.	H	α-helix	trans	-83.8	-35.9	179.1	-70.8	-66.7	0	0	0	113.3	L85 V86 F211	L85-F89 HydrophobicContact CD2-CD2 3.62Å; L85-F89 HydrophobicContact CD2-CE2 3.63Å; L85-F89 HydrophobicContact CG-CD2 4.13Å; L85-F89 HydrophobicContact CG-CE2 3.88Å; L85-F89 VanDerWaalsContact O-CD2 3.32Å; L85-F89 WeakPolarHBondContact O-CD2 3.49Å; L85-F89 PolarHBondContact O-N 3.39Å; V86-F89 PolarHBondContact O-N 2.95Å; F89-F211 HydrophobicContact CZ-CE1 4.33Å
90	F	89.9	Confident	88.2	Confident	136 Å²	136	58.2 Å²	58.2	60%	0.596	32%	0.321	S	S	*	.	S	Bend	trans	-119.7	41.2	-173.2	-59	-77.3	0	0	0	112.8	V86 D92 S93 V94	V86-F90 WeakPolarHBondContact O-CB 3.43Å; V86-F90 PolarHBondContact O-N 3Å; F90-D92 PolarHBondContact O-N 3.46Å; F90-S93 PolarHBondContact O-N 3.4Å; F90-V94 HydrophobicContact CB-CG2 3.83Å; F90-V94 WeakPolarHBondContact O-CB 3.48Å; F90-V94 VanDerWaalsContact O-CG2 3.28Å; F90-V94 WeakPolarHBondContact O-CG2 3.15Å; F90-V94 PolarHBondContact O-N 2.95Å
91	F	85.8	Confident	88.2	Confident	17 Å²	17	60.2 Å²	60.2	8%	0.075	33%	0.332	C	S	.	.	H	α-helix	trans	-50.5	-52.1	-174.7	-172.2	-95.7	0	0	0	112.6	M87 S93 V94 Q95 Q222	M87-F91 HydrophobicContact CE-CD2 3.88Å; M87-F91 HydrophobicContact CE-CE2 3.39Å; M87-F91 HydrophobicContact CE-CZ 4.29Å; M87-F91 HydrophobicContact CG-CD2 3.94Å; M87-F91 HydrophobicContact CG-CE2 4.41Å; M87-F91 WeakPolarHBondContact O-CA 3.21Å; M87-F91 VanDerWaalsContact O-CB 3.3Å; M87-F91 WeakPolarHBondContact O-CB 3.39Å; M87-F91 PolarHBondContact O-N 3.19Å; M87-F91 VanDerWaalsContact O-N 3.14Å; F91-S93 VanDerWaalsContact C-N 3.27Å; F91-S93 PolarHBondContact O-N 3.46Å; F91-V94 PolarHBondContact O-N 3.39Å; F91-Q95 HydrophobicContact CE1-CB 4.38Å; F91-Q95 HydrophobicContact CZ-CB 4.34Å; F91-Q95 VanDerWaalsContact O-CB 3.22Å; F91-Q95 WeakPolarHBondContact O-CB 3.22Å; F91-Q95 WeakPolarHBondContact O-CG 3.31Å; F91-Q95 PolarHBondContact O-N 3Å; F91-Q222 HydrophobicContact CD2-CB 4.34Å; F91-Q222 HydrophobicContact CE1-CB 3.71Å; F91-Q222 HydrophobicContact CE1-CG 4.43Å; F91-Q222 HydrophobicContact CE2-CB 3.48Å; F91-Q222 VanDerWaalsContact CE2-CB 3.48Å; F91-Q222 HydrophobicContact CE2-CG 4.27Å; F91-Q222 HydrophobicContact CZ-CB 3.14Å; F91-Q222 HydrophobicContact CZ-CG 4.16Å
92	D	84.2	Confident	88	Confident	124 Å²	124	59.3 Å²	59.3	66%	0.663	33%	0.325	S	S	*	.	H	α-helix	trans	-60.6	-33	-171.9	-65.2	-28	0	0	0	113.9	F90 Q95	F90-D92 PolarHBondContact O-N 3.46Å; D92-Q95 PolarHBondContact O-NE2 2.82Å
93	S	84.2	Confident	87.9	Confident	89 Å²	89	55.9 Å²	55.9	62%	0.622	31%	0.306	S	S	*	.	H	α-helix	trans	-90	-40	-179.7	-61.7	0	0	0	0	112.4	F90 F91	F90-S93 PolarHBondContact O-N 3.4Å; F91-S93 VanDerWaalsContact C-N 3.27Å; F91-S93 PolarHBondContact O-N 3.46Å
94	V	86.4	Confident	88	Confident	37 Å²	37	56.9 Å²	56.9	22%	0.224	31%	0.309	C	S	.	.	H	α-helix	trans	-78.5	-31.7	-172.9	177.3	0	0	0	0	111.6	V86 F90 F91 V96 V97 F98	V86-V94 HydrophobicContact CG1-CG2 3.88Å; F90-V94 HydrophobicContact CB-CG2 3.83Å; F90-V94 WeakPolarHBondContact O-CB 3.48Å; F90-V94 VanDerWaalsContact O-CG2 3.28Å; F90-V94 WeakPolarHBondContact O-CG2 3.15Å; F90-V94 PolarHBondContact O-N 2.95Å; F91-V94 PolarHBondContact O-N 3.39Å; V94-V96 VanDerWaalsContact C-N 3.25Å; V94-V96 PolarHBondContact O-N 2.87Å; V94-V97 PolarHBondContact O-N 2.82Å; V94-F98 PolarHBondContact O-N 3.38Å
95	Q	86.5	Confident	88.2	Confident	2 Å²	2	59 Å²	59	1%	0.009	32%	0.32	C	S	.	.	H	α-helix	trans	-57.1	-37.3	180	67.2	180	-20.1	0	0	113	F91 D92 F98 T99 A224	F91-Q95 HydrophobicContact CE1-CB 4.38Å; F91-Q95 HydrophobicContact CZ-CB 4.34Å; F91-Q95 VanDerWaalsContact O-CB 3.22Å; F91-Q95 WeakPolarHBondContact O-CB 3.22Å; F91-Q95 WeakPolarHBondContact O-CG 3.31Å; F91-Q95 PolarHBondContact O-N 3Å; D92-Q95 PolarHBondContact O-NE2 2.82Å; Q95-F98 PolarHBondContact O-N 3.08Å; Q95-T99 WeakPolarHBondContact O-CB 3.33Å; Q95-T99 PolarHBondContact O-N 2.76Å; Q95-T99 PolarHBondContact O-OG1 3.39Å; Q95-A224 HydrophobicContact CB-CB 4.32Å
96	V	85.9	Confident	88.3	Confident	22 Å²	22	56 Å²	56	13%	0.133	31%	0.305	C	S	.	.	H	α-helix	trans	-70.1	-43.7	-177.5	-179.5	0	0	0	0	109.6	V94 F98 T99 I100 V230	V94-V96 VanDerWaalsContact C-N 3.25Å; V94-V96 PolarHBondContact O-N 2.87Å; V96-F98 VanDerWaalsContact C-N 3.34Å; V96-F98 PolarHBondContact O-N 3.32Å; V96-T99 PolarHBondContact O-N 3.24Å; V96-I100 HydrophobicContact CG1-CD1 3.94Å; V96-I100 VanDerWaalsContact O-CG1 3.28Å; V96-I100 WeakPolarHBondContact O-CG1 2.92Å; V96-I100 PolarHBondContact O-N 3.12Å; V96-V230 HydrophobicContact CG1-CG1 4.49Å; V96-V230 HydrophobicContact CG1-CG2 4.32Å; V96-V230 HydrophobicContact CG2-CG2 3.88Å
97	V	88.4	Confident	88.3	Confident	101 Å²	101	54.3 Å²	54.3	61%	0.612	30%	0.295	S	S	*	.	H	α-helix	trans	-61.2	-45	176.1	178.8	0	0	0	0	110.4	V94 T99 I100 C101	V94-V97 PolarHBondContact O-N 2.82Å; V97-T99 VanDerWaalsContact C-N 3.34Å; V97-T99 PolarHBondContact O-N 2.96Å; V97-I100 PolarHBondContact O-N 3.02Å; V97-C101 WeakPolarHBondContact O-CB 3.4Å; V97-C101 PolarHBondContact O-N 3.47Å
98	F	86.3	Confident	88.5	Confident	82 Å²	82	58 Å²	58	36%	0.36	31%	0.314	S	S	.	.	H	α-helix	trans	-63.8	-39.3	178.1	-166.8	-93.2	0	0	0	112.3	V94 Q95 V96 C101 T102 L250	V94-F98 PolarHBondContact O-N 3.38Å; Q95-F98 PolarHBondContact O-N 3.08Å; V96-F98 VanDerWaalsContact C-N 3.34Å; V96-F98 PolarHBondContact O-N 3.32Å; F98-C101 PolarHBondContact O-N 3.05Å; F98-T102 WeakPolarHBondContact O-CB 3.28Å; F98-T102 PolarHBondContact O-N 2.91Å; F98-T102 PolarHBondContact O-OG1 3.32Å; F98-L250 HydrophobicContact CD1-CD2 3.4Å; F98-L250 HydrophobicContact CD1-CG 3.98Å; F98-L250 HydrophobicContact CE1-CD2 3.45Å; F98-L250 VanDerWaalsContact CE1-CD2 3.45Å; F98-L250 HydrophobicContact CE1-CG 4.17Å; F98-L250 HydrophobicContact CG-CD2 4.42Å; F98-L250 HydrophobicContact CZ-CD2 4.49Å
99	T	86.1	Confident	88.7	Confident	2 Å²	2	56 Å²	56	1%	0.012	31%	0.306	C	S	.	.	H	α-helix	trans	-67	-42.8	177.3	-56.7	0	0	0	0	111.7	Q95 V96 V97 T102 A103 P227 L248	Q95-T99 WeakPolarHBondContact O-CB 3.33Å; Q95-T99 PolarHBondContact O-N 2.76Å; Q95-T99 PolarHBondContact O-OG1 3.39Å; V96-T99 PolarHBondContact O-N 3.24Å; V97-T99 VanDerWaalsContact C-N 3.34Å; V97-T99 PolarHBondContact O-N 2.96Å; T99-T102 PolarHBondContact O-N 3.07Å; T99-A103 WeakPolarHBondContact O-CB 3.45Å; T99-A103 PolarHBondContact O-N 3.43Å; T99-P227 HydrophobicContact CG2-CG 4.23Å; T99-L248 HydrophobicContact CG2-CD2 4.11Å
100	I	89.1	Confident	88.9	Confident	86 Å²	86	51.9 Å²	51.9	44%	0.441	29%	0.287	S	S	.	.	H	α-helix	trans	-62.6	-47.7	174.5	-66.5	165.6	0	0	0	110.5	V96 V97 T102 A103 V104 P227	V96-I100 HydrophobicContact CG1-CD1 3.94Å; V96-I100 VanDerWaalsContact O-CG1 3.28Å; V96-I100 WeakPolarHBondContact O-CG1 2.92Å; V96-I100 PolarHBondContact O-N 3.12Å; V97-I100 PolarHBondContact O-N 3.02Å; I100-T102 VanDerWaalsContact C-N 3.27Å; I100-T102 PolarHBondContact O-N 2.88Å; I100-A103 WeakPolarHBondContact O-CB 3.37Å; I100-A103 PolarHBondContact O-N 3.24Å; I100-V104 WeakPolarHBondContact O-CG2 3.37Å; I100-V104 PolarHBondContact O-N 3.04Å; I100-P227 HydrophobicContact CD1-CB 4.45Å; I100-P227 HydrophobicContact CG1-CB 3.86Å
101	C	90.1	Very high	89	Confident	75 Å²	75	46 Å²	46	51%	0.507	26%	0.264	S	S	.	.	H	α-helix	trans	-57	-44.4	177.2	-176.4	0	0	0	0	111	V97 F98 V104 L105	V97-C101 WeakPolarHBondContact O-CB 3.4Å; V97-C101 PolarHBondContact O-N 3.47Å; F98-C101 PolarHBondContact O-N 3.05Å; C101-V104 PolarHBondContact O-N 3.22Å; C101-L105 WeakPolarHBondContact O-CB 3.18Å; C101-L105 PolarHBondContact O-N 3.42Å
102	T	87.7	Confident	89.1	Confident	12 Å²	12	46.7 Å²	46.7	7%	0.074	27%	0.267	C	S	.	.	H	α-helix	trans	-71.1	-34.7	179.6	-44.9	0	0	0	0	112.5	F98 T99 I100 L105 A106 L173 P251	F98-T102 WeakPolarHBondContact O-CB 3.28Å; F98-T102 PolarHBondContact O-N 2.91Å; F98-T102 PolarHBondContact O-OG1 3.32Å; T99-T102 PolarHBondContact O-N 3.07Å; I100-T102 VanDerWaalsContact C-N 3.27Å; I100-T102 PolarHBondContact O-N 2.88Å; T102-L105 PolarHBondContact O-N 3.44Å; T102-A106 WeakPolarHBondContact O-CB 3.33Å; T102-A106 PolarHBondContact O-N 3.42Å; T102-L173 HydrophobicContact CG2-CD2 4.26Å; T102-P251 HydrophobicContact CG2-CB 4.32Å; T102-P251 HydrophobicContact CG2-CG 3.25Å
103	A	90.1	Very high	89.4	Confident	15 Å²	15	42.4 Å²	42.4	12%	0.124	24%	0.244	C	C	.	.	H	α-helix	trans	-60.7	-45.4	172.6	0	0	0	0	0	111.1	T99 I100 A106 T107 V154 W157	T99-A103 WeakPolarHBondContact O-CB 3.45Å; T99-A103 PolarHBondContact O-N 3.43Å; I100-A103 WeakPolarHBondContact O-CB 3.37Å; I100-A103 PolarHBondContact O-N 3.24Å; A103-A106 PolarHBondContact O-N 2.92Å; A103-T107 WeakPolarHBondContact O-CG2 3.35Å; A103-T107 PolarHBondContact O-N 3.16Å; A103-V154 HydrophobicContact CB-CG1 4.16Å; A103-W157 HydrophobicContact CB-CZ3 4.22Å
104	V	92.2	Very high	89.6	Confident	78 Å²	78	39.8 Å²	39.8	47%	0.473	22%	0.223	S	C	.	.	H	α-helix	trans	-61.4	-49.4	175.4	173.6	0	0	0	0	110.7	I100 C101 A106 T107 I108	I100-V104 WeakPolarHBondContact O-CG2 3.37Å; I100-V104 PolarHBondContact O-N 3.04Å; C101-V104 PolarHBondContact O-N 3.22Å; V104-A106 VanDerWaalsContact C-N 3.28Å; V104-A106 PolarHBondContact O-N 2.86Å; V104-T107 PolarHBondContact O-N 2.64Å; V104-T107 VanDerWaalsContact O-N 3.14Å; V104-T107 PolarHBondContact O-OG1 2.98Å; V104-I108 HydrophobicContact CG1-CD1 4.07Å; V104-I108 WeakPolarHBondContact O-CG1 3.48Å; V104-I108 PolarHBondContact O-N 2.86Å; V104-I108 VanDerWaalsContact O-N 3.08Å
105	L	92.3	Very high	89.7	Confident	62 Å²	62	39.7 Å²	39.7	33%	0.325	22%	0.221	S	C	.	.	H	α-helix	trans	-62.7	-37.2	179.7	-172.8	58.6	0	0	0	112.1	C101 T102 I108 A109 L173 M177	C101-L105 WeakPolarHBondContact O-CB 3.18Å; C101-L105 PolarHBondContact O-N 3.42Å; T102-L105 PolarHBondContact O-N 3.44Å; L105-I108 PolarHBondContact O-N 2.91Å; L105-A109 VanDerWaalsContact O-CB 3.26Å; L105-A109 WeakPolarHBondContact O-CB 3.35Å; L105-A109 PolarHBondContact O-N 3.35Å; L105-L173 HydrophobicContact CB-CD1 4.46Å; L105-L173 HydrophobicContact CD1-CD1 4.42Å; L105-L173 HydrophobicContact CD2-CD1 3.39Å; L105-L173 HydrophobicContact CG-CD1 3.46Å; L105-L173 VanDerWaalsContact CG-CD1 3.46Å; L105-M177 HydrophobicContact CD2-CE 3.85Å
106	A	92.2	Very high	89.7	Confident	6 Å²	6	42.2 Å²	42.2	5%	0.05	24%	0.237	C	C	.	.	H	α-helix	trans	-65.8	-40.5	174.2	0	0	0	0	0	111.9	T102 A103 V104 I108 A109 F110 V154 L169	T102-A106 WeakPolarHBondContact O-CB 3.33Å; T102-A106 PolarHBondContact O-N 3.42Å; A103-A106 PolarHBondContact O-N 2.92Å; V104-A106 VanDerWaalsContact C-N 3.28Å; V104-A106 PolarHBondContact O-N 2.86Å; A106-I108 PolarHBondContact O-N 3.35Å; A106-A109 PolarHBondContact O-N 2.96Å; A106-F110 VanDerWaalsContact O-CB 3.28Å; A106-F110 WeakPolarHBondContact O-CB 3.27Å; A106-F110 PolarHBondContact O-N 3.14Å; A106-V154 HydrophobicContact CB-CG2 4.44Å; A106-L169 HydrophobicContact CB-CB 4.4Å; A106-L169 HydrophobicContact CB-CD2 4.25Å
107	T	92.4	Very high	89.7	Confident	20 Å²	20	46.6 Å²	46.6	12%	0.123	26%	0.258	C	S	.	.	H	α-helix	trans	-59.4	-46.2	173.7	59.2	0	0	0	0	111.5	A103 V104 F110 A111 S150 V151 V154	A103-T107 WeakPolarHBondContact O-CG2 3.35Å; A103-T107 PolarHBondContact O-N 3.16Å; V104-T107 PolarHBondContact O-N 2.64Å; V104-T107 VanDerWaalsContact O-N 3.14Å; V104-T107 PolarHBondContact O-OG1 2.98Å; T107-F110 PolarHBondContact O-N 3.2Å; T107-A111 VanDerWaalsContact O-CB 3.23Å; T107-A111 WeakPolarHBondContact O-CB 3.41Å; T107-A111 PolarHBondContact O-N 2.68Å; T107-S150 WeakPolarHBondContact O-CB 3.37Å; T107-S150 PolarHBondContact O-OG 2.81Å; T107-V151 HydrophobicContact CG2-CG2 4.36Å; T107-V154 HydrophobicContact CG2-CB 3.75Å; T107-V154 HydrophobicContact CG2-CG1 3.95Å; T107-V154 HydrophobicContact CG2-CG2 3.58Å
108	I	91.9	Very high	89.5	Confident	90 Å²	90	42 Å²	42	46%	0.462	23%	0.23	S	C	.	.	H	α-helix	trans	-63.6	-47.1	178.8	-63.3	167.7	0	0	0	110.4	V104 L105 A106 F110 A111 F112	V104-I108 HydrophobicContact CG1-CD1 4.07Å; V104-I108 WeakPolarHBondContact O-CG1 3.48Å; V104-I108 PolarHBondContact O-N 2.86Å; V104-I108 VanDerWaalsContact O-N 3.08Å; L105-I108 PolarHBondContact O-N 2.91Å; A106-I108 PolarHBondContact O-N 3.35Å; I108-F110 VanDerWaalsContact C-N 3.35Å; I108-F110 PolarHBondContact O-N 2.83Å; I108-A111 PolarHBondContact O-N 3.47Å; I108-F112 WeakPolarHBondContact O-CB 3.09Å; I108-F112 PolarHBondContact O-N 3.35Å
109	A	93	Very high	89.4	Confident	2 Å²	2	42.3 Å²	42.3	2%	0.017	23%	0.233	C	C	.	.	H	α-helix	trans	-60.5	-43.6	179.1	0	0	0	0	0	112.1	L105 A106 F112 L113 A176	L105-A109 VanDerWaalsContact O-CB 3.26Å; L105-A109 WeakPolarHBondContact O-CB 3.35Å; L105-A109 PolarHBondContact O-N 3.35Å; A106-A109 PolarHBondContact O-N 2.96Å; A109-F112 WeakPolarHBondContact O-CB 3.45Å; A109-F112 PolarHBondContact O-N 3.03Å; A109-L113 WeakPolarHBondContact O-CG 3.4Å; A109-L113 PolarHBondContact O-N 3.5Å; A109-A176 HydrophobicContact CB-CB 3.46Å; A109-A176 VanDerWaalsContact CB-CB 3.46Å
110	F	91.8	Very high	89.2	Confident	31 Å²	31	50.7 Å²	50.7	14%	0.136	27%	0.265	C	S	.	.	H	α-helix	trans	-75.9	-36.7	-178.2	-142.6	-93.4	0	0	0	112.2	A106 T107 I108 F112 L113 L114 L153 L169	A106-F110 VanDerWaalsContact O-CB 3.28Å; A106-F110 WeakPolarHBondContact O-CB 3.27Å; A106-F110 PolarHBondContact O-N 3.14Å; T107-F110 PolarHBondContact O-N 3.2Å; I108-F110 VanDerWaalsContact C-N 3.35Å; I108-F110 PolarHBondContact O-N 2.83Å; F110-F112 VanDerWaalsContact C-N 3.27Å; F110-F112 PolarHBondContact O-N 3.21Å; F110-L113 PolarHBondContact O-N 3.45Å; F110-L113 VanDerWaalsContact O-N 3.16Å; F110-L114 HydrophobicContact CD1-CD1 3.56Å; F110-L114 HydrophobicContact CD1-CD2 4.38Å; F110-L114 HydrophobicContact CD1-CG 3.7Å; F110-L114 HydrophobicContact CE1-CD1 3.77Å; F110-L114 HydrophobicContact CE1-CD2 3.94Å; F110-L114 HydrophobicContact CE1-CG 3.79Å; F110-L114 WeakPolarHBondContact O-CB 3.41Å; F110-L114 WeakPolarHBondContact O-CG 3.44Å; F110-L114 PolarHBondContact O-N 2.83Å; F110-L153 HydrophobicContact CD1-CD1 3.67Å; F110-L153 HydrophobicContact CE1-CD1 3.18Å; F110-L153 HydrophobicContact CZ-CD1 4.04Å; F110-L169 HydrophobicContact CB-CD2 4.5Å; F110-L169 HydrophobicContact CD2-CD2 3.94Å; F110-L169 HydrophobicContact CE2-CD2 4.46Å; F110-L169 HydrophobicContact CG-CD2 4.29Å
111	A	92.1	Very high	88.9	Confident	12 Å²	12	51.7 Å²	51.7	10%	0.099	27%	0.271	C	S	.	.	H	α-helix	trans	-56.8	-45.8	170.3	0	0	0	0	0	110.5	T107 I108 L114 L115 F147	T107-A111 VanDerWaalsContact O-CB 3.23Å; T107-A111 WeakPolarHBondContact O-CB 3.41Å; T107-A111 PolarHBondContact O-N 2.68Å; I108-A111 PolarHBondContact O-N 3.47Å; A111-L114 PolarHBondContact O-N 2.89Å; A111-L115 PolarHBondContact O-N 2.93Å; A111-F147 HydrophobicContact CB-CD2 4.34Å
112	F	89	Confident	88.3	Confident	33 Å²	33	49.6 Å²	49.6	15%	0.145	26%	0.256	C	S	.	.	H	α-helix	trans	-59	-50.4	173.7	174.7	-116.2	0	0	0	110.9	R34 M38 I108 A109 F110 L114 L115 P116 A176 A179 F180	R34-F112 HydrophobicContact CG-CE1 4.32Å; R34-F112 HydrophobicContact CG-CZ 4.15Å; R34-F112 VanDerWaalsContact CZ-CE1 3.43Å; R34-F112 VanDerWaalsContact NH2-CD1 3.25Å; R34-F112 VanDerWaalsContact NH2-CE1 3.26Å; R34-F112 VanDerWaalsContact NH2-CE2 3.33Å; R34-F112 VanDerWaalsContact NH2-CG 3.32Å; R34-F112 VanDerWaalsContact NH2-CZ 3.29Å; R34-F112 PolarHBondContact NH2-O 3.43Å; M38-F112 HydrophobicContact CE-CE2 4.38Å; M38-F112 HydrophobicContact CE-CZ 4.25Å; M38-F112 HydrophobicContact CG-CZ 4.48Å; M38-F112 HydrophobicContact SD-CE2 4.1Å; M38-F112 HydrophobicContact SD-CZ 3.53Å; M38-F112 VanDerWaalsContact SD-CZ 3.53Å; I108-F112 WeakPolarHBondContact O-CB 3.09Å; I108-F112 PolarHBondContact O-N 3.35Å; A109-F112 WeakPolarHBondContact O-CB 3.45Å; A109-F112 PolarHBondContact O-N 3.03Å; F110-F112 VanDerWaalsContact C-N 3.27Å; F110-F112 PolarHBondContact O-N 3.21Å; F112-L114 VanDerWaalsContact C-N 3.33Å; F112-L114 PolarHBondContact O-N 3.29Å; F112-L115 WeakPolarHBondContact O-CB 3.29Å; F112-L115 PolarHBondContact O-N 3.01Å; F112-P116 WeakPolarHBondContact O-CD 3.15Å; F112-A176 HydrophobicContact CD1-CB 4.48Å; F112-A179 HydrophobicContact CE1-CB 3.88Å; F112-A179 HydrophobicContact CZ-CB 4.24Å; F112-F180 HydrophobicContact CB-CE2 4.21Å; F112-F180 HydrophobicContact CB-CZ 4.32Å; F112-F180 AromaticContact CD1-CE2 3.59Å; F112-F180 HydrophobicContact CD1-CE2 3.59Å; F112-F180 AromaticContact CD1-CZ 3.92Å; F112-F180 HydrophobicContact CD1-CZ 3.92Å; F112-F180 HydrophobicContact CD2-CE1 4.48Å; F112-F180 HydrophobicContact CD2-CE2 4.04Å; F112-F180 AromaticContact CD2-CZ 3.5Å; F112-F180 HydrophobicContact CD2-CZ 3.5Å; F112-F180 AromaticContact CE1-CE2 3.8Å; F112-F180 HydrophobicContact CE1-CE2 3.8Å; F112-F180 AromaticContact CE1-CZ 3.98Å; F112-F180 HydrophobicContact CE1-CZ 3.98Å; F112-F180 HydrophobicContact CE2-CE1 4.24Å; F112-F180 HydrophobicContact CE2-CE2 4.26Å; F112-F180 AromaticContact CE2-CZ 3.61Å; F112-F180 HydrophobicContact CE2-CZ 3.61Å; F112-F180 AromaticContact CG-CE2 3.7Å; F112-F180 HydrophobicContact CG-CE2 3.7Å; F112-F180 AromaticContact CG-CZ 3.66Å; F112-F180 HydrophobicContact CG-CZ 3.66Å; F112-F180 HydrophobicContact CZ-CE1 4.41Å; F112-F180 HydrophobicContact CZ-CE2 4.14Å; F112-F180 AromaticContact CZ-CZ 3.84Å; F112-F180 HydrophobicContact CZ-CZ 3.84Å
113	L	88.8	Confident	87.5	Confident	34 Å²	34	58.9 Å²	58.9	18%	0.178	29%	0.29	C	S	.	.	H	α-helix	trans	-59.7	-39.6	179.7	-74.6	-163.1	0	0	0	114.3	Y30 R34 A109 F110 L115 P116 G172 V175	Y30-L113 HydrophobicContact CE1-CD2 4.12Å; R34-L113 VanDerWaalsContact NH1-CD2 3.25Å; A109-L113 WeakPolarHBondContact O-CG 3.4Å; A109-L113 PolarHBondContact O-N 3.5Å; F110-L113 PolarHBondContact O-N 3.45Å; F110-L113 VanDerWaalsContact O-N 3.16Å; L113-L115 VanDerWaalsContact C-N 3.34Å; L113-P116 VanDerWaalsContact O-CD 3.32Å; L113-P116 WeakPolarHBondContact O-CD 3.18Å; L113-P116 WeakPolarHBondContact O-CG 3.39Å; L113-G172 VanDerWaalsContact CD1-CA 3.44Å; L113-V175 HydrophobicContact CD2-CB 4.16Å; L113-V175 HydrophobicContact CD2-CG1 3.66Å
114	L	89.5	Confident	86.4	Confident	34 Å²	34	63.3 Å²	63.3	18%	0.178	32%	0.317	C	S	.	.	H	α-helix	trans	-76.6	-19.3	-179.8	-70.9	-179.4	0	0	0	113.4	F110 A111 F112 M117 C118 L149 L153	F110-L114 HydrophobicContact CD1-CD1 3.56Å; F110-L114 HydrophobicContact CD1-CD2 4.38Å; F110-L114 HydrophobicContact CD1-CG 3.7Å; F110-L114 HydrophobicContact CE1-CD1 3.77Å; F110-L114 HydrophobicContact CE1-CD2 3.94Å; F110-L114 HydrophobicContact CE1-CG 3.79Å; F110-L114 WeakPolarHBondContact O-CB 3.41Å; F110-L114 WeakPolarHBondContact O-CG 3.44Å; F110-L114 PolarHBondContact O-N 2.83Å; A111-L114 PolarHBondContact O-N 2.89Å; F112-L114 VanDerWaalsContact C-N 3.33Å; F112-L114 PolarHBondContact O-N 3.29Å; L114-M117 WeakPolarHBondContact O-CB 3.22Å; L114-M117 PolarHBondContact O-N 3.37Å; L114-M117 VanDerWaalsContact O-N 3.1Å; L114-C118 PolarHBondContact O-N 2.85Å; L114-C118 PolarHBondContact O-SG 3.39Å; L114-L149 HydrophobicContact CD1-CB 3.82Å; L114-L153 HydrophobicContact CD1-CD1 4.26Å
115	L	88.1	Confident	84.8	Confident	35 Å²	35	64.7 Å²	64.7	18%	0.183	33%	0.329	C	S	.	.	H	α-helix	trans	-51.9	-52.2	-178.2	-172.2	66.5	0	0	0	114	A111 F112 L113 M117 C118 Q119 A142 E143	A111-L115 PolarHBondContact O-N 2.93Å; F112-L115 WeakPolarHBondContact O-CB 3.29Å; F112-L115 PolarHBondContact O-N 3.01Å; L113-L115 VanDerWaalsContact C-N 3.34Å; L115-M117 VanDerWaalsContact C-N 3.28Å; L115-M117 PolarHBondContact O-N 3.26Å; L115-C118 PolarHBondContact O-N 3.29Å; L115-Q119 HydrophobicContact CD1-CG 4.38Å; L115-Q119 HydrophobicContact CG-CG 4.4Å; L115-Q119 WeakPolarHBondContact O-CB 3.2Å; L115-Q119 VanDerWaalsContact O-CG 3.3Å; L115-Q119 WeakPolarHBondContact O-CG 3.27Å; L115-Q119 PolarHBondContact O-N 3.32Å; L115-A142 HydrophobicContact CD1-CB 4.48Å; L115-E143 HydrophobicContact CD1-CB 4.38Å; L115-E143 HydrophobicContact CD1-CG 3.68Å
116	P	85.9	Confident	83.1	Confident	55 Å²	55	64.2 Å²	64.2	36%	0.357	33%	0.331	S	S	.	.	H	α-helix	trans	-60.7	-36	178	22.8	-34.9	0	0	0	112.9	F112 L113 Y120	F112-P116 WeakPolarHBondContact O-CD 3.15Å; L113-P116 VanDerWaalsContact O-CD 3.32Å; L113-P116 WeakPolarHBondContact O-CD 3.18Å; L113-P116 WeakPolarHBondContact O-CG 3.39Å; P116-Y120 WeakPolarHBondContact O-CB 3.3Å; P116-Y120 PolarHBondContact O-N 3.44Å
117	M	85.6	Confident	80.9	Confident	113 Å²	113	69.2 Å²	69.2	56%	0.557	36%	0.363	S	S	*	.	H	α-helix	trans	-67.5	-45.6	175.8	-62.1	-60.4	-70.9	0	0	110.7	L114 L115 Q119 Y120 L121	L114-M117 WeakPolarHBondContact O-CB 3.22Å; L114-M117 PolarHBondContact O-N 3.37Å; L114-M117 VanDerWaalsContact O-N 3.1Å; L115-M117 VanDerWaalsContact C-N 3.28Å; L115-M117 PolarHBondContact O-N 3.26Å; M117-Q119 VanDerWaalsContact C-N 3.35Å; M117-Q119 PolarHBondContact O-N 3.41Å; M117-Y120 WeakPolarHBondContact O-CB 3.13Å; M117-Y120 PolarHBondContact O-N 3.39Å; M117-L121 WeakPolarHBondContact O-CD1 3.31Å; M117-L121 PolarHBondContact O-N 3.47Å
118	C	86.2	Confident	79	Confident	5 Å²	5	77.3 Å²	77.3	3%	0.034	40%	0.399	C	S	.	.	H	α-helix	trans	-65	-38.4	178.2	-64.9	0	0	0	0	111.7	L114 L115 L121 T122 A142 L145	L114-C118 PolarHBondContact O-N 2.85Å; L114-C118 PolarHBondContact O-SG 3.39Å; L115-C118 PolarHBondContact O-N 3.29Å; C118-L121 PolarHBondContact O-N 2.88Å; C118-T122 VanDerWaalsContact O-CB 3.31Å; C118-T122 WeakPolarHBondContact O-CB 3.31Å; C118-T122 VanDerWaalsContact O-CG2 3.25Å; C118-T122 WeakPolarHBondContact O-CG2 3.39Å; C118-T122 PolarHBondContact O-N 3.3Å; C118-T122 PolarHBondContact O-OG1 2.92Å; C118-A142 HydrophobicContact CB-CB 4.36Å; C118-L145 HydrophobicContact CB-CD2 4.35Å
119	Q	84.2	Confident	76.9	Confident	89 Å²	89	79.1 Å²	79.1	42%	0.416	41%	0.41	S	S	.	.	H	α-helix	trans	-62.5	-42.5	173	-74.3	176.2	-15	0	0	111.3	L115 M117 T122 R123 A142	L115-Q119 HydrophobicContact CD1-CG 4.38Å; L115-Q119 HydrophobicContact CG-CG 4.4Å; L115-Q119 WeakPolarHBondContact O-CB 3.2Å; L115-Q119 VanDerWaalsContact O-CG 3.3Å; L115-Q119 WeakPolarHBondContact O-CG 3.27Å; L115-Q119 PolarHBondContact O-N 3.32Å; M117-Q119 VanDerWaalsContact C-N 3.35Å; M117-Q119 PolarHBondContact O-N 3.41Å; Q119-T122 WeakPolarHBondContact CA-OG1 3.45Å; Q119-T122 PolarHBondContact O-N 3.03Å; Q119-T122 PolarHBondContact O-OG1 2.89Å; Q119-R123 WeakPolarHBondContact O-CG 3.4Å; Q119-R123 PolarHBondContact O-N 3.18Å; Q119-A142 HydrophobicContact CB-CB 4.48Å; Q119-A142 HydrophobicContact CG-CB 3.73Å
120	Y	81.7	Confident	74.8	Confident	177 Å²	177	86.4 Å²	86.4	69%	0.694	44%	0.441	S	S	*	.	H	α-helix	trans	-62.7	-45.6	175	-179.3	-101.1	0	0	0	112.2	P116 M117 T122 P124	P116-Y120 WeakPolarHBondContact O-CB 3.3Å; P116-Y120 PolarHBondContact O-N 3.44Å; M117-Y120 WeakPolarHBondContact O-CB 3.13Å; M117-Y120 PolarHBondContact O-N 3.39Å; Y120-T122 PolarHBondContact O-N 2.84Å; Y120-P124 WeakPolarHBondContact O-CD 3.32Å
121	L	82.7	Confident	72.7	Confident	108 Å²	108	90.6 Å²	90.6	57%	0.565	46%	0.464	S	S	*	.	H	α-helix	trans	-67.5	-33.1	178.4	-88.1	79	0	0	0	113.1	M117 C118 P124	M117-L121 WeakPolarHBondContact O-CD1 3.31Å; M117-L121 PolarHBondContact O-N 3.47Å; C118-L121 PolarHBondContact O-N 2.88Å; L121-P124 WeakPolarHBondContact O-CD 3.22Å; L121-P124 WeakPolarHBondContact O-CG 3.22Å
122	T	77.5	Confident	70.3	Confident	30 Å²	30	93.3 Å²	93.3	18%	0.184	48%	0.482	C	S	.	.	H	α-helix	trans	-87.9	-18.5	-178.7	54.4	0	0	0	0	113.7	C118 Q119 Y120 C125 S126 L145	C118-T122 VanDerWaalsContact O-CB 3.31Å; C118-T122 WeakPolarHBondContact O-CB 3.31Å; C118-T122 VanDerWaalsContact O-CG2 3.25Å; C118-T122 WeakPolarHBondContact O-CG2 3.39Å; C118-T122 PolarHBondContact O-N 3.3Å; C118-T122 PolarHBondContact O-OG1 2.92Å; Q119-T122 WeakPolarHBondContact CA-OG1 3.45Å; Q119-T122 PolarHBondContact O-N 3.03Å; Q119-T122 PolarHBondContact O-OG1 2.89Å; Y120-T122 PolarHBondContact O-N 2.84Å; T122-C125 PolarHBondContact O-N 2.89Å; T122-S126 PolarHBondContact O-N 3.34Å; T122-L145 HydrophobicContact CG2-CD2 3.98Å
123	R	69.3	Low	68	Low	208 Å²	208	99 Å²	99	79%	0.785	51%	0.507	S	S	*	.	T	Hydrogen-bonded Turn	trans	-49.1	-47.7	173.6	-93.6	-149.3	-171.9	-147.4	5.1	114.5	Q119 C125	Q119-R123 WeakPolarHBondContact O-CG 3.4Å; Q119-R123 PolarHBondContact O-N 3.18Å; R123-C125 VanDerWaalsContact C-N 3.29Å; R123-C125 PolarHBondContact O-N 3.39Å
124	P	68.8	Low	65.8	Low	107 Å²	107	101.4 Å²	101.4	70%	0.695	54%	0.54	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.3	-26.4	178	25.4	-34.6	0	0	0	113.2	Y120 L121	Y120-P124 WeakPolarHBondContact O-CD 3.32Å; L121-P124 WeakPolarHBondContact O-CD 3.22Å; L121-P124 WeakPolarHBondContact O-CG 3.22Å
125	C	57.6	Low	63.3	Low	108 Å²	108	105.6 Å²	105.6	73%	0.73	57%	0.571	S	S	*	*	T	Hydrogen-bonded Turn	trans	-92.5	-18.3	-173.6	-65.4	0	0	0	0	114.1	T122 R123	T122-C125 PolarHBondContact O-N 2.89Å; R123-C125 VanDerWaalsContact C-N 3.29Å; R123-C125 PolarHBondContact O-N 3.39Å
126	S	55.7	Low	61	Low	52 Å²	52	108.2 Å²	108.2	36%	0.364	59%	0.591	S	S	.	*			trans	-126.8	97.5	-173.6	-166.2	0	0	0	0	112	T122 Q128	T122-S126 PolarHBondContact O-N 3.34Å; S126-Q128 VanDerWaalsContact C-N 3.33Å; S126-Q128 PolarHBondContact O-N 3.49Å
127	P	47	Very low	59.5	Low	110 Å²	110	107.6 Å²	107.6	71%	0.714	60%	0.595	S	S	*	*			trans	-68.7	90.5	168.4	27.7	-32	0	0	0	109.2	N129	P127-N129 PolarHBondContact O-N 2.99Å
128	Q	52.8	Low	58.3	Low	190 Å²	190	109.7 Å²	109.7	89%	0.888	60%	0.596	S	S	*	*	S	Bend	trans	41.8	12.4	162.3	-75.6	174.5	-21.8	0	0	119.5	S126 K130	S126-Q128 VanDerWaalsContact C-N 3.33Å; S126-Q128 PolarHBondContact O-N 3.49Å; Q128-K130 PolarHBondContact O-N 2.94Å; Q128-K130 VanDerWaalsContact O-N 3.11Å
129	N	46.8	Very low	57.2	Low	129 Å²	129	114.6 Å²	114.6	69%	0.69	62%	0.617	S	S	*	*			trans	-83.6	97.2	177	-90	-12	0	0	0	108.2	P127 I131	P127-N129 PolarHBondContact O-N 2.99Å; N129-I131 VanDerWaalsContact C-N 3.28Å; N129-I131 PolarHBondContact O-N 3.35Å
130	K	49.8	Very low	56.7	Low	155 Å²	155	113.3 Å²	113.3	67%	0.674	62%	0.615	S	S	*	*			trans	-60.7	91.5	166	-66.5	173.6	179.8	179.2	0	107.8	Q128 S132	Q128-K130 PolarHBondContact O-N 2.94Å; Q128-K130 VanDerWaalsContact O-N 3.11Å; K130-S132 PolarHBondContact O-N 2.83Å; K130-S132 VanDerWaalsContact O-N 3.12Å
131	I	48.5	Very low	56.7	Low	119 Å²	119	107.3 Å²	107.3	61%	0.61	60%	0.603	S	S	*	*			trans	-63.1	111.9	172.7	-63.3	169.5	0	0	0	106.9	N129	N129-I131 VanDerWaalsContact C-N 3.28Å; N129-I131 PolarHBondContact O-N 3.35Å
132	S	41	Very low	56.7	Low	69 Å²	69	102.2 Å²	102.2	48%	0.483	58%	0.576	S	S	.	*			trans	-89.7	110.4	179.3	-172	0	0	0	0	108.6	K130 G134	K130-S132 PolarHBondContact O-N 2.83Å; K130-S132 VanDerWaalsContact O-N 3.12Å; S132-G134 PolarHBondContact O-N 2.88Å
133	F	40.4	Very low	57.2	Low	152 Å²	152	104.2 Å²	104.2	67%	0.667	58%	0.583	S	S	*	*	B	Isolated β-bridge	trans	-83.2	108.5	169.1	-135.9	-94	0	0	0	108.1	C135 C136 G137	F133-C135 PolarHBondContact O-N 3.38Å; F133-C136 PolarHBondContact O-N 3.33Å; F133-G137 PolarHBondContact O-N 3.49Å
134	G	43.2	Very low	58.1	Low	84 Å²	84	100 Å²	100	87%	0.866	58%	0.576	S	S	*	*	T	Hydrogen-bonded Turn	trans	-59.6	-8.6	-168.2	0	0	0	0	0	117	S132	S132-G134 PolarHBondContact O-N 2.88Å
135	C	37.2	Very low	59.1	Low	123 Å²	123	98.2 Å²	98.2	83%	0.831	56%	0.56	S	S	*	*	T	Hydrogen-bonded Turn	trans	-104.6	-14.6	-179.7	-163.6	0	0	0	0	114.3	F133	F133-C135 PolarHBondContact O-N 3.38Å
136	C	40.3	Very low	60.8	Low	90 Å²	90	93.3 Å²	93.3	61%	0.608	53%	0.527	S	S	*	.	T	Hydrogen-bonded Turn	trans	-140.5	12.9	-170.1	-147.6	0	0	0	0	115.2	F133 F139	F133-C136 PolarHBondContact O-N 3.33Å; C136-F139 HydrophobicContact CB-CD2 4.46Å; C136-F139 HydrophobicContact CB-CE2 3.77Å; C136-F139 WeakPolarHBondContact O-CE2 3.34Å
137	G	53.4	Low	62.5	Low	42 Å²	42	95.8 Å²	95.8	43%	0.433	53%	0.531	S	S	.	.	B	Isolated β-bridge	trans	94.9	-176.4	177	0	0	0	0	0	113.7	F133 F139	F133-G137 PolarHBondContact O-N 3.49Å; G137-F139 PolarHBondContact O-N 2.83Å
138	R	60.1	Low	64.7	Low	156 Å²	156	94 Å²	94	59%	0.589	52%	0.521	S	S	*	.			trans	-85.4	89	-177.7	-59.9	177.9	74.6	78.4	-8.9	109.3
139	F	63.7	Low	66.6	Low	109 Å²	109	88.3 Å²	88.3	48%	0.478	50%	0.496	S	S	.	.			trans	-88.7	132.3	171.3	-71.2	-70.2	0	0	0	110.8	C136 G137	C136-F139 HydrophobicContact CB-CD2 4.46Å; C136-F139 HydrophobicContact CB-CE2 3.77Å; C136-F139 WeakPolarHBondContact O-CE2 3.34Å; G137-F139 PolarHBondContact O-N 2.83Å
140	T	73.8	Confident	68.9	Low	61 Å²	61	82.1 Å²	82.1	37%	0.374	46%	0.463	S	S	.	.			trans	-76.7	143.8	169.5	177.4	0	0	0	0	109.8	A142 E143 L144	T140-A142 HydrophobicContact CG2-CB 4.12Å; T140-A142 PolarHBondContact O-N 2.74Å; T140-E143 HydrophobicContact CG2-CB 3.87Å; T140-E143 HydrophobicContact CG2-CG 3.4Å; T140-E143 PolarHBondContact N-OE2 3.36Å; T140-E143 VanDerWaalsContact N-OE2 3.12Å; T140-E143 WeakPolarHBondContact O-CB 3.16Å; T140-E143 PolarHBondContact O-N 3.44Å; T140-L144 PolarHBondContact O-N 3.31Å
141	A	81.3	Confident	71	Confident	52 Å²	52	77 Å²	77	43%	0.43	45%	0.445	S	S	.	.	H	α-helix	trans	-54	-29.3	175.8	0	0	0	0	0	112	L145	A141-L145 VanDerWaalsContact O-CB 3.28Å; A141-L145 WeakPolarHBondContact O-CB 3.42Å; A141-L145 PolarHBondContact O-N 3.29Å
142	A	83.9	Confident	73.2	Confident	1 Å²	1	76.3 Å²	76.3	1%	0.008	44%	0.44	C	S	.	.	H	α-helix	trans	-65.2	-37.1	174.7	0	0	0	0	0	113.5	L115 C118 Q119 T140 S146	L115-A142 HydrophobicContact CD1-CB 4.48Å; C118-A142 HydrophobicContact CB-CB 4.36Å; Q119-A142 HydrophobicContact CB-CB 4.48Å; Q119-A142 HydrophobicContact CG-CB 3.73Å; T140-A142 HydrophobicContact CG2-CB 4.12Å; T140-A142 PolarHBondContact O-N 2.74Å; A142-S146 WeakPolarHBondContact O-CB 3.26Å; A142-S146 PolarHBondContact O-N 2.63Å; A142-S146 PolarHBondContact O-OG 3.41Å; A142-S146 VanDerWaalsContact O-OG 3.07Å
143	E	87.4	Confident	75.6	Confident	72 Å²	72	75.1 Å²	75.1	34%	0.336	43%	0.429	S	S	.	.	H	α-helix	trans	-70.2	-45.3	179.2	-80.6	163.3	178	0	0	110.7	L115 T140 L145 S146 F147	L115-E143 HydrophobicContact CD1-CB 4.38Å; L115-E143 HydrophobicContact CD1-CG 3.68Å; T140-E143 HydrophobicContact CG2-CB 3.87Å; T140-E143 HydrophobicContact CG2-CG 3.4Å; T140-E143 PolarHBondContact N-OE2 3.36Å; T140-E143 VanDerWaalsContact N-OE2 3.12Å; T140-E143 WeakPolarHBondContact O-CB 3.16Å; T140-E143 PolarHBondContact O-N 3.44Å; E143-L145 VanDerWaalsContact C-N 3.31Å; E143-L145 PolarHBondContact O-N 2.99Å; E143-S146 WeakPolarHBondContact CA-OG 3.47Å; E143-S146 PolarHBondContact O-N 3.29Å; E143-S146 PolarHBondContact O-OG 3.1Å; E143-F147 VanDerWaalsContact O-CB 3.28Å; E143-F147 WeakPolarHBondContact O-CB 3.38Å; E143-F147 PolarHBondContact O-N 3.45Å
144	L	88.1	Confident	78.1	Confident	120 Å²	120	68.3 Å²	68.3	63%	0.628	40%	0.399	S	S	*	.	H	α-helix	trans	-63.1	-41.7	177	-176.5	62.3	0	0	0	110.8	T140 F147 S148	T140-L144 PolarHBondContact O-N 3.31Å; L144-F147 PolarHBondContact O-N 3.44Å; L144-S148 VanDerWaalsContact O-CB 3.25Å; L144-S148 WeakPolarHBondContact O-CB 3.47Å; L144-S148 PolarHBondContact O-N 2.88Å
145	L	90.2	Very high	80.3	Confident	69 Å²	69	68.7 Å²	68.7	36%	0.361	38%	0.381	S	S	.	.	H	α-helix	trans	-63.9	-47.7	175.6	-178.7	62.1	0	0	0	111.4	C118 T122 A141 E143 F147 S148 L149	C118-L145 HydrophobicContact CB-CD2 4.35Å; T122-L145 HydrophobicContact CG2-CD2 3.98Å; A141-L145 VanDerWaalsContact O-CB 3.28Å; A141-L145 WeakPolarHBondContact O-CB 3.42Å; A141-L145 PolarHBondContact O-N 3.29Å; E143-L145 VanDerWaalsContact C-N 3.31Å; E143-L145 PolarHBondContact O-N 2.99Å; L145-F147 VanDerWaalsContact C-N 3.32Å; L145-F147 PolarHBondContact O-N 3.33Å; L145-S148 PolarHBondContact O-N 2.85Å; L145-L149 HydrophobicContact CD1-CD1 4.13Å; L145-L149 HydrophobicContact CD1-CG 4.2Å; L145-L149 HydrophobicContact CG-CD1 4.06Å; L145-L149 WeakPolarHBondContact O-CB 3.16Å; L145-L149 VanDerWaalsContact O-CG 3.3Å; L145-L149 WeakPolarHBondContact O-CG 3.17Å; L145-L149 PolarHBondContact O-N 2.91Å
146	S	92	Very high	82.8	Confident	4 Å²	4	65.7 Å²	65.7	3%	0.028	36%	0.356	C	S	.	.	H	α-helix	trans	-63.1	-39.2	178.5	59	0	0	0	0	112.2	A142 E143 S150	A142-S146 WeakPolarHBondContact O-CB 3.26Å; A142-S146 PolarHBondContact O-N 2.63Å; A142-S146 PolarHBondContact O-OG 3.41Å; A142-S146 VanDerWaalsContact O-OG 3.07Å; E143-S146 WeakPolarHBondContact CA-OG 3.47Å; E143-S146 PolarHBondContact O-N 3.29Å; E143-S146 PolarHBondContact O-OG 3.1Å; S146-S150 WeakPolarHBondContact O-CB 3.35Å; S146-S150 PolarHBondContact O-N 2.91Å; S146-S150 PolarHBondContact O-OG 3.46Å
147	F	92.4	Very high	85.1	Confident	105 Å²	105	61.5 Å²	61.5	46%	0.461	33%	0.328	S	S	.	.	H	α-helix	trans	-66.8	-47.2	176.9	-176.4	-103.3	0	0	0	111	A111 E143 L144 L145 L149 S150 V151	A111-F147 HydrophobicContact CB-CD2 4.34Å; E143-F147 VanDerWaalsContact O-CB 3.28Å; E143-F147 WeakPolarHBondContact O-CB 3.38Å; E143-F147 PolarHBondContact O-N 3.45Å; L144-F147 PolarHBondContact O-N 3.44Å; L145-F147 VanDerWaalsContact C-N 3.32Å; L145-F147 PolarHBondContact O-N 3.33Å; F147-L149 PolarHBondContact O-N 3.44Å; F147-S150 PolarHBondContact O-N 3.23Å; F147-S150 VanDerWaalsContact O-N 3.17Å; F147-S150 PolarHBondContact O-OG 3Å; F147-V151 HydrophobicContact CD1-CG2 4.33Å; F147-V151 HydrophobicContact CE1-CG2 3.93Å; F147-V151 HydrophobicContact CE2-CG2 4.33Å; F147-V151 HydrophobicContact CZ-CG2 3.93Å; F147-V151 WeakPolarHBondContact O-CG2 3.17Å; F147-V151 PolarHBondContact O-N 3.26Å
148	S	93.2	Very high	86.6	Confident	71 Å²	71	60 Å²	60	50%	0.497	31%	0.309	S	S	.	.	H	α-helix	trans	-59.7	-44.8	177.4	-177.6	0	0	0	0	112.3	L144 L145 S150 V151 M152	L144-S148 VanDerWaalsContact O-CB 3.25Å; L144-S148 WeakPolarHBondContact O-CB 3.47Å; L144-S148 PolarHBondContact O-N 2.88Å; L145-S148 PolarHBondContact O-N 2.85Å; S148-S150 VanDerWaalsContact C-N 3.34Å; S148-S150 PolarHBondContact O-N 3.49Å; S148-V151 PolarHBondContact O-N 3.38Å; S148-M152 WeakPolarHBondContact O-CB 3.19Å; S148-M152 PolarHBondContact O-N 2.92Å
149	L	93.3	Very high	87.8	Confident	71 Å²	71	57.5 Å²	57.5	37%	0.372	31%	0.308	S	S	.	.	H	α-helix	trans	-63.5	-39.3	175.6	-71.2	174.5	0	0	0	112.1	L114 L145 F147 M152 L153	L114-L149 HydrophobicContact CD1-CB 3.82Å; L145-L149 HydrophobicContact CD1-CD1 4.13Å; L145-L149 HydrophobicContact CD1-CG 4.2Å; L145-L149 HydrophobicContact CG-CD1 4.06Å; L145-L149 WeakPolarHBondContact O-CB 3.16Å; L145-L149 VanDerWaalsContact O-CG 3.3Å; L145-L149 WeakPolarHBondContact O-CG 3.17Å; L145-L149 PolarHBondContact O-N 2.91Å; F147-L149 PolarHBondContact O-N 3.44Å; L149-M152 PolarHBondContact O-N 3.31Å; L149-L153 WeakPolarHBondContact O-CG 3.38Å; L149-L153 PolarHBondContact O-N 3.24Å
150	S	94.3	Very high	88.8	Confident	0 Å²	0	56.1 Å²	56.1	0%	0	31%	0.308	C	S	.	.	H	α-helix	trans	-64.8	-43.2	178.3	74.9	0	0	0	0	112.5	T107 S146 F147 S148 M152 L153 V154	T107-S150 WeakPolarHBondContact O-CB 3.37Å; T107-S150 PolarHBondContact O-OG 2.81Å; S146-S150 WeakPolarHBondContact O-CB 3.35Å; S146-S150 PolarHBondContact O-N 2.91Å; S146-S150 PolarHBondContact O-OG 3.46Å; F147-S150 PolarHBondContact O-N 3.23Å; F147-S150 VanDerWaalsContact O-N 3.17Å; F147-S150 PolarHBondContact O-OG 3Å; S148-S150 VanDerWaalsContact C-N 3.34Å; S148-S150 PolarHBondContact O-N 3.49Å; S150-M152 VanDerWaalsContact C-N 3.31Å; S150-M152 PolarHBondContact O-N 2.72Å; S150-L153 PolarHBondContact O-N 3.27Å; S150-V154 WeakPolarHBondContact O-CG2 3.02Å; S150-V154 PolarHBondContact O-N 3.37Å
151	V	94.3	Very high	88.9	Confident	48 Å²	48	54.2 Å²	54.2	29%	0.291	30%	0.3	S	S	.	.	H	α-helix	trans	-62.3	-43.6	175.5	171.5	0	0	0	0	109.7	T107 F147 S148 L153 V154 L155	T107-V151 HydrophobicContact CG2-CG2 4.36Å; F147-V151 HydrophobicContact CD1-CG2 4.33Å; F147-V151 HydrophobicContact CE1-CG2 3.93Å; F147-V151 HydrophobicContact CE2-CG2 4.33Å; F147-V151 HydrophobicContact CZ-CG2 3.93Å; F147-V151 WeakPolarHBondContact O-CG2 3.17Å; F147-V151 PolarHBondContact O-N 3.26Å; S148-V151 PolarHBondContact O-N 3.38Å; V151-L153 PolarHBondContact O-N 3.32Å; V151-V154 PolarHBondContact O-N 2.98Å; V151-L155 HydrophobicContact CG1-CD1 3.97Å; V151-L155 HydrophobicContact CG1-CG 4.3Å; V151-L155 WeakPolarHBondContact O-CB 3.46Å; V151-L155 VanDerWaalsContact O-CG 3.28Å; V151-L155 WeakPolarHBondContact O-CG 3.13Å; V151-L155 PolarHBondContact O-N 2.99Å
152	M	93.7	Very high	88.9	Confident	103 Å²	103	55.8 Å²	55.8	51%	0.507	30%	0.299	S	S	.	.	H	α-helix	trans	-61.6	-44	179	-172.1	-98.2	-176.1	0	0	112.2	S148 L149 S150 L155 I156	S148-M152 WeakPolarHBondContact O-CB 3.19Å; S148-M152 PolarHBondContact O-N 2.92Å; L149-M152 PolarHBondContact O-N 3.31Å; S150-M152 VanDerWaalsContact C-N 3.31Å; S150-M152 PolarHBondContact O-N 2.72Å; M152-L155 PolarHBondContact O-N 2.88Å; M152-I156 HydrophobicContact CE-CD1 3.45Å; M152-I156 VanDerWaalsContact CE-CD1 3.45Å; M152-I156 HydrophobicContact CE-CG1 4.33Å; M152-I156 WeakPolarHBondContact O-CG1 3.06Å; M152-I156 PolarHBondContact O-N 3.49Å; M152-I156 HydrophobicContact SD-CD1 3.43Å; M152-I156 WeakPolarHBondContact SD-CD1 3.46Å; M152-I156 HydrophobicContact SD-CG1 4.36Å
153	L	92.4	Very high	88.6	Confident	45 Å²	45	61.3 Å²	61.3	24%	0.236	32%	0.32	C	S	.	.	H	α-helix	trans	-66.2	-39.8	176.5	-71.2	171.8	0	0	0	112.8	F110 L114 L149 S150 V151 I156 W157 L165	F110-L153 HydrophobicContact CD1-CD1 3.67Å; F110-L153 HydrophobicContact CE1-CD1 3.18Å; F110-L153 HydrophobicContact CZ-CD1 4.04Å; L114-L153 HydrophobicContact CD1-CD1 4.26Å; L149-L153 WeakPolarHBondContact O-CG 3.38Å; L149-L153 PolarHBondContact O-N 3.24Å; S150-L153 PolarHBondContact O-N 3.27Å; V151-L153 PolarHBondContact O-N 3.32Å; L153-I156 PolarHBondContact O-N 2.93Å; L153-W157 WeakPolarHBondContact O-CB 3.4Å; L153-W157 PolarHBondContact O-N 3.14Å; L153-L165 HydrophobicContact CD2-CD1 4.5Å
154	V	92.1	Very high	88.4	Confident	8 Å²	8	62.8 Å²	62.8	5%	0.048	33%	0.329	C	S	.	.	H	α-helix	trans	-67	-38.4	175.2	172.8	0	0	0	0	110.8	A103 A106 T107 S150 V151 W157 V158 L169	A103-V154 HydrophobicContact CB-CG1 4.16Å; A106-V154 HydrophobicContact CB-CG2 4.44Å; T107-V154 HydrophobicContact CG2-CB 3.75Å; T107-V154 HydrophobicContact CG2-CG1 3.95Å; T107-V154 HydrophobicContact CG2-CG2 3.58Å; S150-V154 WeakPolarHBondContact O-CG2 3.02Å; S150-V154 PolarHBondContact O-N 3.37Å; V151-V154 PolarHBondContact O-N 2.98Å; V154-W157 HydrophobicContact CG1-CE3 4.11Å; V154-W157 WeakPolarHBondContact O-CB 2.9Å; V154-W157 PolarHBondContact O-N 3.43Å; V154-W157 VanDerWaalsContact O-N 3.17Å; V154-V158 HydrophobicContact CG1-CG2 4.4Å; V154-V158 WeakPolarHBondContact O-CG2 3.28Å; V154-V158 PolarHBondContact O-N 3.17Å; V154-L169 HydrophobicContact CG2-CD1 4.26Å; V154-L169 HydrophobicContact CG2-CD2 3.76Å
155	L	90.2	Very high	88.3	Confident	92 Å²	92	58.7 Å²	58.7	48%	0.482	31%	0.308	S	S	.	.	H	α-helix	trans	-63.5	-43.7	174.2	-72	174.9	0	0	0	112	V151 M152 W157 V158 L159	V151-L155 HydrophobicContact CG1-CD1 3.97Å; V151-L155 HydrophobicContact CG1-CG 4.3Å; V151-L155 WeakPolarHBondContact O-CB 3.46Å; V151-L155 VanDerWaalsContact O-CG 3.28Å; V151-L155 WeakPolarHBondContact O-CG 3.13Å; V151-L155 PolarHBondContact O-N 2.99Å; M152-L155 PolarHBondContact O-N 2.88Å; L155-W157 VanDerWaalsContact C-N 3.25Å; L155-W157 PolarHBondContact O-N 2.89Å; L155-V158 PolarHBondContact O-N 3.31Å; L155-L159 WeakPolarHBondContact O-CB 3.3Å; L155-L159 VanDerWaalsContact O-CG 3.27Å; L155-L159 WeakPolarHBondContact O-CG 3.42Å; L155-L159 PolarHBondContact O-N 3.31Å
156	I	89.8	Confident	88	Confident	60 Å²	60	56 Å²	56	31%	0.308	29%	0.293	S	S	.	.	H	α-helix	trans	-58.1	-42.8	172	-68.3	166.4	0	0	0	110.1	M152 L153 L159 T160 L165	M152-I156 HydrophobicContact CE-CD1 3.45Å; M152-I156 VanDerWaalsContact CE-CD1 3.45Å; M152-I156 HydrophobicContact CE-CG1 4.33Å; M152-I156 WeakPolarHBondContact O-CG1 3.06Å; M152-I156 PolarHBondContact O-N 3.49Å; M152-I156 HydrophobicContact SD-CD1 3.43Å; M152-I156 WeakPolarHBondContact SD-CD1 3.46Å; M152-I156 HydrophobicContact SD-CG1 4.36Å; L153-I156 PolarHBondContact O-N 2.93Å; I156-L159 PolarHBondContact O-N 2.94Å; I156-T160 VanDerWaalsContact O-CB 3.29Å; I156-T160 WeakPolarHBondContact O-CB 3.31Å; I156-T160 PolarHBondContact O-N 3.21Å; I156-T160 PolarHBondContact O-OG1 3.29Å; I156-T160 VanDerWaalsContact O-OG1 3.1Å; I156-L165 HydrophobicContact CB-CD2 4.07Å; I156-L165 HydrophobicContact CG2-CD2 3.67Å
157	W	87.1	Confident	87.7	Confident	3 Å²	3	56.1 Å²	56.1	1%	0.011	29%	0.294	C	S	.	.	H	α-helix	trans	-61.4	-45.6	178	169.6	73.9	0	0	0	113	A103 L153 V154 L155 L159 G161 L165 M166 L169 L248 P251	A103-W157 HydrophobicContact CB-CZ3 4.22Å; L153-W157 WeakPolarHBondContact O-CB 3.4Å; L153-W157 PolarHBondContact O-N 3.14Å; V154-W157 HydrophobicContact CG1-CE3 4.11Å; V154-W157 WeakPolarHBondContact O-CB 2.9Å; V154-W157 PolarHBondContact O-N 3.43Å; V154-W157 VanDerWaalsContact O-N 3.17Å; L155-W157 VanDerWaalsContact C-N 3.25Å; L155-W157 PolarHBondContact O-N 2.89Å; W157-L159 VanDerWaalsContact C-N 3.27Å; W157-L159 PolarHBondContact O-N 2.91Å; W157-G161 WeakPolarHBondContact O-CA 3.25Å; W157-G161 PolarHBondContact O-N 2.71Å; W157-L165 HydrophobicContact CB-CB 4.49Å; W157-L165 HydrophobicContact CB-CD2 3.64Å; W157-L165 HydrophobicContact CB-CG 3.97Å; W157-M166 VanDerWaalsContact CE2-SD 3.52Å; W157-M166 HydrophobicContact CZ2-CE 3.89Å; W157-M166 HydrophobicContact CZ2-SD 3.55Å; W157-M166 VanDerWaalsContact CZ2-SD 3.55Å; W157-M166 VanDerWaalsContact NE1-CE 3.26Å; W157-M166 PolarHBondContact NE1-SD 3.22Å; W157-L169 HydrophobicContact CB-CD1 3.67Å; W157-L169 HydrophobicContact CD2-CD1 3.46Å; W157-L169 VanDerWaalsContact CD2-CD1 3.46Å; W157-L169 HydrophobicContact CE3-CD1 3.91Å; W157-L169 HydrophobicContact CG-CD1 3.33Å; W157-L248 HydrophobicContact CD2-CD2 4.44Å; W157-L248 HydrophobicContact CE3-CD2 4.23Å; W157-L248 HydrophobicContact CH2-CD2 3.33Å; W157-L248 HydrophobicContact CH2-CG 4.11Å; W157-L248 HydrophobicContact CZ2-CD2 3.57Å; W157-L248 HydrophobicContact CZ2-CG 3.82Å; W157-L248 HydrophobicContact CZ3-CD2 3.69Å; W157-P251 HydrophobicContact CH2-CG 4.47Å; W157-P251 HydrophobicContact CZ2-CG 4.45Å
158	V	85.9	Confident	87.6	Confident	9 Å²	9	52.3 Å²	52.3	6%	0.055	28%	0.282	C	S	.	.	H	α-helix	trans	-66.7	-31.4	177.9	-171.9	0	0	0	0	111.5	V154 L155 P227 L228 V245 L248	V154-V158 HydrophobicContact CG1-CG2 4.4Å; V154-V158 WeakPolarHBondContact O-CG2 3.28Å; V154-V158 PolarHBondContact O-N 3.17Å; L155-V158 PolarHBondContact O-N 3.31Å; V158-P227 HydrophobicContact CG1-CG 3.99Å; V158-L228 HydrophobicContact CB-CD1 4.02Å; V158-L228 HydrophobicContact CB-CG 4.45Å; V158-L228 HydrophobicContact CG1-CB 4.18Å; V158-L228 HydrophobicContact CG1-CD1 3.49Å; V158-L228 VanDerWaalsContact CG1-CD1 3.49Å; V158-L228 HydrophobicContact CG1-CG 3.51Å; V158-V245 WeakPolarHBondContact O-CG1 3.43Å; V158-L248 HydrophobicContact CG1-CD2 4.42Å; V158-L248 HydrophobicContact CG2-CD2 4.49Å
159	L	85.8	Confident	87.4	Confident	105 Å²	105	49.2 Å²	49.2	55%	0.55	26%	0.26	S	S	.	.	H	α-helix	trans	-80.1	-47	179	-69.9	171	0	0	0	113.3	L155 I156 W157 L228	L155-L159 WeakPolarHBondContact O-CB 3.3Å; L155-L159 VanDerWaalsContact O-CG 3.27Å; L155-L159 WeakPolarHBondContact O-CG 3.42Å; L155-L159 PolarHBondContact O-N 3.31Å; I156-L159 PolarHBondContact O-N 2.94Å; W157-L159 VanDerWaalsContact C-N 3.27Å; W157-L159 PolarHBondContact O-N 2.91Å; L159-L228 HydrophobicContact CD2-CD1 3.45Å; L159-L228 VanDerWaalsContact CD2-CD1 3.45Å; L159-L228 HydrophobicContact CG-CD1 3.94Å
160	T	83.2	Confident	87.2	Confident	79 Å²	79	45.9 Å²	45.9	49%	0.485	24%	0.242	S	C	.	.	H	α-helix	trans	-88.8	-26.8	-173	-49.2	0	0	0	0	112.5	I156 H162 P246	I156-T160 VanDerWaalsContact O-CB 3.29Å; I156-T160 WeakPolarHBondContact O-CB 3.31Å; I156-T160 PolarHBondContact O-N 3.21Å; I156-T160 PolarHBondContact O-OG1 3.29Å; I156-T160 VanDerWaalsContact O-OG1 3.1Å; T160-H162 HydrophobicContact CG2-CB 3.92Å; T160-H162 PolarHBondContact O-N 3.4Å; T160-H162 VanDerWaalsContact O-N 3.08Å; T160-P246 WeakPolarHBondContact O-CG 3.42Å
161	G	77.3	Confident	87.1	Confident	21 Å²	21	48.5 Å²	48.5	22%	0.216	26%	0.255	C	S	.	.			trans	55.3	24.5	-174.5	0	0	0	0	0	114.1	W157 W163	W157-G161 WeakPolarHBondContact O-CA 3.25Å; W157-G161 PolarHBondContact O-N 2.71Å; G161-W163 PolarHBondContact O-N 3.06Å
162	H	81.1	Confident	87	Confident	85 Å²	85	46.2 Å²	46.2	39%	0.394	24%	0.241	S	C	.	.			trans	-67	129.3	-174.3	-166.6	-79	0	0	0	110.7	T160 L164 L165 M166	T160-H162 HydrophobicContact CG2-CB 3.92Å; T160-H162 PolarHBondContact O-N 3.4Å; T160-H162 VanDerWaalsContact O-N 3.08Å; H162-L164 VanDerWaalsContact C-N 3.34Å; H162-L164 VanDerWaalsContact CE1-CB 3.47Å; H162-L164 WeakPolarHBondContact CE1-CB 3.42Å; H162-L164 VanDerWaalsContact ND1-CB 3.29Å; H162-L164 WeakPolarHBondContact ND1-CB 3.35Å; H162-L164 PolarHBondContact ND1-N 3.22Å; H162-L164 PolarHBondContact O-N 3.39Å; H162-L165 HydrophobicContact CB-CB 4.39Å; H162-L165 PolarHBondContact O-N 3.26Å; H162-M166 PolarHBondContact O-N 2.88Å; H162-M166 VanDerWaalsContact O-N 3.1Å
163	W	77.5	Confident	87	Confident	118 Å²	118	42.1 Å²	42.1	45%	0.447	22%	0.221	S	C	.	.	H	α-helix	trans	-55.1	-43.6	-178.1	71	-75.3	0	0	0	113.2	G161 L165 M166 D167 P257	G161-W163 PolarHBondContact O-N 3.06Å; W163-L165 VanDerWaalsContact C-N 3.26Å; W163-L165 PolarHBondContact O-N 3.18Å; W163-M166 VanDerWaalsContact O-CB 3.26Å; W163-M166 WeakPolarHBondContact O-CB 3.23Å; W163-M166 PolarHBondContact O-N 3.48Å; W163-M166 VanDerWaalsContact O-N 3.16Å; W163-D167 PolarHBondContact O-N 2.89Å; W163-P257 HydrophobicContact CE3-CG 4.31Å; W163-P257 VanDerWaalsContact CH2-CD 3.42Å; W163-P257 HydrophobicContact CH2-CG 3.29Å; W163-P257 HydrophobicContact CZ2-CG 3.96Å; W163-P257 HydrophobicContact CZ3-CG 3.52Å
164	L	82.5	Confident	87	Confident	103 Å²	103	40 Å²	40	54%	0.539	21%	0.21	S	C	.	.	H	α-helix	trans	-59.6	-36.1	176.9	-175.3	64.9	0	0	0	113	H162 D167 A168	H162-L164 VanDerWaalsContact C-N 3.34Å; H162-L164 VanDerWaalsContact CE1-CB 3.47Å; H162-L164 WeakPolarHBondContact CE1-CB 3.42Å; H162-L164 VanDerWaalsContact ND1-CB 3.29Å; H162-L164 WeakPolarHBondContact ND1-CB 3.35Å; H162-L164 PolarHBondContact ND1-N 3.22Å; H162-L164 PolarHBondContact O-N 3.39Å; L164-D167 PolarHBondContact O-N 3.19Å; L164-A168 WeakPolarHBondContact O-CB 3.23Å; L164-A168 PolarHBondContact O-N 3.43Å
165	L	85.4	Confident	87.1	Confident	34 Å²	34	39.8 Å²	39.8	18%	0.178	21%	0.209	C	C	.	.	H	α-helix	trans	-76.7	-33.2	-178.6	-154.3	62.5	0	0	0	110.3	L153 I156 W157 H162 W163 A168 L169	L153-L165 HydrophobicContact CD2-CD1 4.5Å; I156-L165 HydrophobicContact CB-CD2 4.07Å; I156-L165 HydrophobicContact CG2-CD2 3.67Å; W157-L165 HydrophobicContact CB-CB 4.49Å; W157-L165 HydrophobicContact CB-CD2 3.64Å; W157-L165 HydrophobicContact CB-CG 3.97Å; H162-L165 HydrophobicContact CB-CB 4.39Å; H162-L165 PolarHBondContact O-N 3.26Å; W163-L165 VanDerWaalsContact C-N 3.26Å; W163-L165 PolarHBondContact O-N 3.18Å; L165-A168 PolarHBondContact O-N 2.92Å; L165-L169 WeakPolarHBondContact O-CB 3.43Å; L165-L169 VanDerWaalsContact O-CG 3.24Å; L165-L169 WeakPolarHBondContact O-CG 3.28Å; L165-L169 PolarHBondContact O-N 3.47Å
166	M	84.1	Confident	87.2	Confident	12 Å²	12	35.7 Å²	35.7	6%	0.059	19%	0.189	C	C	.	.	H	α-helix	trans	-56.3	-51.5	167.5	-62.7	-97.1	178.2	0	0	111.3	W157 H162 W163 A168 L169 A170 L248	W157-M166 VanDerWaalsContact CE2-SD 3.52Å; W157-M166 HydrophobicContact CZ2-CE 3.89Å; W157-M166 HydrophobicContact CZ2-SD 3.55Å; W157-M166 VanDerWaalsContact CZ2-SD 3.55Å; W157-M166 VanDerWaalsContact NE1-CE 3.26Å; W157-M166 PolarHBondContact NE1-SD 3.22Å; H162-M166 PolarHBondContact O-N 2.88Å; H162-M166 VanDerWaalsContact O-N 3.1Å; W163-M166 VanDerWaalsContact O-CB 3.26Å; W163-M166 WeakPolarHBondContact O-CB 3.23Å; W163-M166 PolarHBondContact O-N 3.48Å; W163-M166 VanDerWaalsContact O-N 3.16Å; M166-A168 PolarHBondContact O-N 3Å; M166-L169 PolarHBondContact O-N 3.35Å; M166-A170 WeakPolarHBondContact O-CB 3.38Å; M166-A170 PolarHBondContact O-N 2.85Å; M166-L248 HydrophobicContact CE-CB 3.94Å; M166-L248 HydrophobicContact CE-CD1 3.82Å; M166-L248 HydrophobicContact CE-CG 3.46Å; M166-L248 VanDerWaalsContact CE-CG 3.46Å
167	D	86.8	Confident	87.4	Confident	6 Å²	6	36 Å²	36	3%	0.032	19%	0.19	C	C	.	.	H	α-helix	trans	-64.5	-40.8	-179.2	-74.4	-20.3	0	0	0	111.3	W163 L164 L169 A170 M171 L254 V255	W163-D167 PolarHBondContact O-N 2.89Å; L164-D167 PolarHBondContact O-N 3.19Å; D167-L169 PolarHBondContact O-N 3.34Å; D167-A170 PolarHBondContact O-N 3.42Å; D167-M171 WeakPolarHBondContact O-CB 3.43Å; D167-M171 VanDerWaalsContact O-CG 3.24Å; D167-M171 WeakPolarHBondContact O-CG 3.38Å; D167-M171 PolarHBondContact O-N 3.43Å; D167-L254 HydrophobicContact CB-CD2 4.34Å; D167-V255 PolarHBondContact OD1-N 2.93Å; D167-V255 VanDerWaalsContact OD2-O 3.07Å
168	A	89.2	Confident	87.8	Confident	26 Å²	26	35.9 Å²	35.9	22%	0.215	19%	0.189	C	C	.	.	H	α-helix	trans	-60.6	-43.3	176	0	0	0	0	0	112.5	L164 L165 M166 M171 G172	L164-A168 WeakPolarHBondContact O-CB 3.23Å; L164-A168 PolarHBondContact O-N 3.43Å; L165-A168 PolarHBondContact O-N 2.92Å; M166-A168 PolarHBondContact O-N 3Å; A168-M171 HydrophobicContact CB-CE 4.46Å; A168-G172 PolarHBondContact O-N 3.42Å
169	L	89	Confident	88.1	Confident	5 Å²	5	35.5 Å²	35.5	3%	0.026	19%	0.187	C	C	.	.	H	α-helix	trans	-67.8	-40.7	176.4	-68.2	173.3	0	0	0	111.7	A106 F110 V154 W157 L165 M166 D167 G172 L173	A106-L169 HydrophobicContact CB-CB 4.4Å; A106-L169 HydrophobicContact CB-CD2 4.25Å; F110-L169 HydrophobicContact CB-CD2 4.5Å; F110-L169 HydrophobicContact CD2-CD2 3.94Å; F110-L169 HydrophobicContact CE2-CD2 4.46Å; F110-L169 HydrophobicContact CG-CD2 4.29Å; V154-L169 HydrophobicContact CG2-CD1 4.26Å; V154-L169 HydrophobicContact CG2-CD2 3.76Å; W157-L169 HydrophobicContact CB-CD1 3.67Å; W157-L169 HydrophobicContact CD2-CD1 3.46Å; W157-L169 VanDerWaalsContact CD2-CD1 3.46Å; W157-L169 HydrophobicContact CE3-CD1 3.91Å; W157-L169 HydrophobicContact CG-CD1 3.33Å; L165-L169 WeakPolarHBondContact O-CB 3.43Å; L165-L169 VanDerWaalsContact O-CG 3.24Å; L165-L169 WeakPolarHBondContact O-CG 3.28Å; L165-L169 PolarHBondContact O-N 3.47Å; M166-L169 PolarHBondContact O-N 3.35Å; D167-L169 PolarHBondContact O-N 3.34Å; L169-G172 PolarHBondContact O-N 2.65Å; L169-L173 WeakPolarHBondContact O-CB 3.44Å; L169-L173 PolarHBondContact O-N 3.44Å
170	A	89.4	Confident	88.3	Confident	1 Å²	1	32.5 Å²	32.5	1%	0.008	17%	0.169	C	C	.	.	H	α-helix	trans	-61.9	-44.2	175.1	0	0	0	0	0	112.5	M166 D167 G172 L173 C174 L254 I269	M166-A170 WeakPolarHBondContact O-CB 3.38Å; M166-A170 PolarHBondContact O-N 2.85Å; D167-A170 PolarHBondContact O-N 3.42Å; A170-G172 VanDerWaalsContact C-N 3.32Å; A170-G172 PolarHBondContact O-N 2.97Å; A170-L173 PolarHBondContact O-N 3Å; A170-C174 WeakPolarHBondContact O-CB 3.2Å; A170-C174 PolarHBondContact O-N 3.42Å; A170-L254 HydrophobicContact CB-CD2 3.82Å; A170-I269 HydrophobicContact CB-CD1 3.52Å; A170-I269 HydrophobicContact CB-CG1 4.42Å
171	M	91.5	Very high	88.7	Confident	55 Å²	55	29.5 Å²	29.5	27%	0.271	15%	0.151	S	C	.	.	H	α-helix	trans	-60.4	-43.1	172.8	-73.4	-170.8	-68.8	0	0	111.1	I23 L27 D167 A168 C174 V175 L254	I23-M171 HydrophobicContact CG2-SD 3.94Å; L27-M171 HydrophobicContact CD1-CB 4.48Å; L27-M171 HydrophobicContact CD1-CG 4Å; L27-M171 HydrophobicContact CD2-CB 3.79Å; L27-M171 HydrophobicContact CD2-CG 3.98Å; L27-M171 HydrophobicContact CD2-SD 4.4Å; D167-M171 WeakPolarHBondContact O-CB 3.43Å; D167-M171 VanDerWaalsContact O-CG 3.24Å; D167-M171 WeakPolarHBondContact O-CG 3.38Å; D167-M171 PolarHBondContact O-N 3.43Å; A168-M171 HydrophobicContact CB-CE 4.46Å; M171-C174 WeakPolarHBondContact O-CB 3.45Å; M171-C174 PolarHBondContact O-N 2.99Å; M171-V175 WeakPolarHBondContact O-CG2 3.33Å; M171-V175 PolarHBondContact O-N 3.17Å; M171-L254 HydrophobicContact CG-CD2 3.92Å
172	G	92.9	Very high	89.3	Confident	0 Å²	0	29.4 Å²	29.4	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-61.4	-45.3	176.3	0	0	0	0	0	113.2	L113 A168 L169 A170 C174 V175 A176	L113-G172 VanDerWaalsContact CD1-CA 3.44Å; A168-G172 PolarHBondContact O-N 3.42Å; L169-G172 PolarHBondContact O-N 2.65Å; A170-G172 VanDerWaalsContact C-N 3.32Å; A170-G172 PolarHBondContact O-N 2.97Å; G172-C174 VanDerWaalsContact C-N 3.34Å; G172-C174 PolarHBondContact O-N 3.48Å; G172-V175 PolarHBondContact O-N 3.42Å; G172-A176 WeakPolarHBondContact O-CB 3.18Å; G172-A176 PolarHBondContact O-N 3.26Å
173	L	92.8	Very high	89.8	Confident	17 Å²	17	25.5 Å²	25.5	9%	0.089	13%	0.126	C	C	.	.	H	α-helix	trans	-58.8	-45.4	174	177.2	61.9	0	0	0	111.7	T102 L105 L169 A170 A176 M177	T102-L173 HydrophobicContact CG2-CD2 4.26Å; L105-L173 HydrophobicContact CB-CD1 4.46Å; L105-L173 HydrophobicContact CD1-CD1 4.42Å; L105-L173 HydrophobicContact CD2-CD1 3.39Å; L105-L173 HydrophobicContact CG-CD1 3.46Å; L105-L173 VanDerWaalsContact CG-CD1 3.46Å; L169-L173 WeakPolarHBondContact O-CB 3.44Å; L169-L173 PolarHBondContact O-N 3.44Å; A170-L173 PolarHBondContact O-N 3Å; L173-A176 PolarHBondContact O-N 2.85Å; L173-M177 HydrophobicContact CD1-CE 4.43Å; L173-M177 HydrophobicContact CD1-CG 4.15Å; L173-M177 WeakPolarHBondContact O-CB 3.48Å; L173-M177 VanDerWaalsContact O-CG 3.27Å; L173-M177 WeakPolarHBondContact O-CG 3.26Å; L173-M177 PolarHBondContact O-N 2.85Å
174	C	93.3	Very high	90.3	Very high	1 Å²	1	22 Å²	22	1%	0.007	12%	0.119	C	C	.	.	H	α-helix	trans	-59.1	-50.1	178.3	-178.8	0	0	0	0	111.5	A170 M171 G172 M177 I178 I269 I272 V273	A170-C174 WeakPolarHBondContact O-CB 3.2Å; A170-C174 PolarHBondContact O-N 3.42Å; M171-C174 WeakPolarHBondContact O-CB 3.45Å; M171-C174 PolarHBondContact O-N 2.99Å; G172-C174 VanDerWaalsContact C-N 3.34Å; G172-C174 PolarHBondContact O-N 3.48Å; C174-M177 PolarHBondContact O-N 3.21Å; C174-I178 WeakPolarHBondContact O-CG1 3.48Å; C174-I178 PolarHBondContact O-N 3.04Å; C174-I269 HydrophobicContact CB-CG2 4.24Å; C174-I272 VanDerWaalsContact SG-CG2 3.51Å; C174-V273 HydrophobicContact CB-CG2 4.05Å; C174-V273 VanDerWaalsContact SG-CG2 3.55Å
175	V	94.2	Very high	90.8	Very high	3 Å²	3	17.7 Å²	17.7	2%	0.018	10%	0.097	C	C	.	.	H	α-helix	trans	-63.9	-43.9	179.1	174.2	0	0	0	0	111.5	L27 Y30 L113 M171 G172 I178 A179	L27-V175 HydrophobicContact CD2-CG2 3.64Å; Y30-V175 HydrophobicContact CD1-CB 4.42Å; Y30-V175 HydrophobicContact CD1-CG1 3.58Å; Y30-V175 HydrophobicContact CD1-CG2 3.9Å; Y30-V175 HydrophobicContact CE1-CG1 3.69Å; L113-V175 HydrophobicContact CD2-CB 4.16Å; L113-V175 HydrophobicContact CD2-CG1 3.66Å; M171-V175 WeakPolarHBondContact O-CG2 3.33Å; M171-V175 PolarHBondContact O-N 3.17Å; G172-V175 PolarHBondContact O-N 3.42Å; V175-I178 PolarHBondContact O-N 2.98Å; V175-A179 VanDerWaalsContact O-CB 3.27Å; V175-A179 WeakPolarHBondContact O-CB 3.39Å; V175-A179 PolarHBondContact O-N 3.33Å
176	A	93.1	Very high	91.1	Very high	7 Å²	7	16.1 Å²	16.1	6%	0.058	9%	0.089	C	C	.	.	H	α-helix	trans	-61.9	-44.6	178.5	0	0	0	0	0	111.3	A109 F112 G172 L173 I178 A179 F180	A109-A176 HydrophobicContact CB-CB 3.46Å; A109-A176 VanDerWaalsContact CB-CB 3.46Å; F112-A176 HydrophobicContact CD1-CB 4.48Å; G172-A176 WeakPolarHBondContact O-CB 3.18Å; G172-A176 PolarHBondContact O-N 3.26Å; L173-A176 PolarHBondContact O-N 2.85Å; A176-I178 PolarHBondContact O-N 3.47Å; A176-A179 PolarHBondContact O-N 3.45Å; A176-F180 HydrophobicContact CB-CD2 4.21Å; A176-F180 HydrophobicContact CB-CE2 4.34Å; A176-F180 WeakPolarHBondContact O-CB 3.41Å; A176-F180 WeakPolarHBondContact O-CD2 3.39Å; A176-F180 PolarHBondContact O-N 3.41Å
177	M	93.2	Very high	91.6	Very high	67 Å²	67	20.5 Å²	20.5	33%	0.33	11%	0.107	S	C	.	.	H	α-helix	trans	-58.9	-48.5	175.3	-75.3	-63.4	-151.3	0	0	111.5	L105 L173 C174 A179 V181 V273	L105-M177 HydrophobicContact CD2-CE 3.85Å; L173-M177 HydrophobicContact CD1-CE 4.43Å; L173-M177 HydrophobicContact CD1-CG 4.15Å; L173-M177 WeakPolarHBondContact O-CB 3.48Å; L173-M177 VanDerWaalsContact O-CG 3.27Å; L173-M177 WeakPolarHBondContact O-CG 3.26Å; L173-M177 PolarHBondContact O-N 2.85Å; C174-M177 PolarHBondContact O-N 3.21Å; M177-A179 VanDerWaalsContact C-N 3.26Å; M177-A179 PolarHBondContact O-N 3.49Å; M177-V181 WeakPolarHBondContact O-CB 3.41Å; M177-V181 WeakPolarHBondContact O-CG2 3.32Å; M177-V181 PolarHBondContact O-N 2.96Å; M177-V181 HydrophobicContact SD-CG2 4.07Å; M177-V273 HydrophobicContact CB-CG1 3.87Å; M177-V273 HydrophobicContact CB-CG2 4.34Å
178	I	94.7	Very high	91.9	Very high	0 Å²	0	20.5 Å²	20.5	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-64	-32.5	178.7	-64.4	170.6	0	0	0	111.9	I28 C174 V175 A176 C280	I28-I178 HydrophobicContact CG1-CD1 4.19Å; C174-I178 WeakPolarHBondContact O-CG1 3.48Å; C174-I178 PolarHBondContact O-N 3.04Å; V175-I178 PolarHBondContact O-N 2.98Å; A176-I178 PolarHBondContact O-N 3.47Å; I178-C280 HydrophobicContact CG2-CB 3.97Å
179	A	92.4	Very high	92.1	Very high	0 Å²	0	19.3 Å²	19.3	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-75.3	-46.8	-179.5	0	0	0	0	0	113.1	R34 S35 M38 F112 V175 A176 M177	R34-A179 HydrophobicContact CG-CB 4.47Å; S35-A179 PolarHBondContact OG-O 2.91Å; M38-A179 HydrophobicContact SD-CB 4.14Å; F112-A179 HydrophobicContact CE1-CB 3.88Å; F112-A179 HydrophobicContact CZ-CB 4.24Å; V175-A179 VanDerWaalsContact O-CB 3.27Å; V175-A179 WeakPolarHBondContact O-CB 3.39Å; V175-A179 PolarHBondContact O-N 3.33Å; A176-A179 PolarHBondContact O-N 3.45Å; M177-A179 VanDerWaalsContact C-N 3.26Å; M177-A179 PolarHBondContact O-N 3.49Å
180	F	91	Very high	92.3	Very high	42 Å²	42	19.8 Å²	19.8	18%	0.184	10%	0.102	C	C	.	.	H	α-helix	trans	-87.8	-35.1	-172.9	-71.6	-64	0	0	0	114	M38 S64 Q66 F112 A176	M38-F180 HydrophobicContact CE-CD1 3.66Å; M38-F180 HydrophobicContact CE-CE1 3.45Å; M38-F180 VanDerWaalsContact CE-CE1 3.45Å; M38-F180 HydrophobicContact CE-CZ 4.34Å; S64-F180 VanDerWaalsContact O-CD1 3.23Å; S64-F180 WeakPolarHBondContact O-CD1 3.09Å; Q66-F180 PolarHBondContact N-O 3.1Å; F112-F180 HydrophobicContact CB-CE2 4.21Å; F112-F180 HydrophobicContact CB-CZ 4.32Å; F112-F180 AromaticContact CD1-CE2 3.59Å; F112-F180 HydrophobicContact CD1-CE2 3.59Å; F112-F180 AromaticContact CD1-CZ 3.92Å; F112-F180 HydrophobicContact CD1-CZ 3.92Å; F112-F180 HydrophobicContact CD2-CE1 4.48Å; F112-F180 HydrophobicContact CD2-CE2 4.04Å; F112-F180 AromaticContact CD2-CZ 3.5Å; F112-F180 HydrophobicContact CD2-CZ 3.5Å; F112-F180 AromaticContact CE1-CE2 3.8Å; F112-F180 HydrophobicContact CE1-CE2 3.8Å; F112-F180 AromaticContact CE1-CZ 3.98Å; F112-F180 HydrophobicContact CE1-CZ 3.98Å; F112-F180 HydrophobicContact CE2-CE1 4.24Å; F112-F180 HydrophobicContact CE2-CE2 4.26Å; F112-F180 AromaticContact CE2-CZ 3.61Å; F112-F180 HydrophobicContact CE2-CZ 3.61Å; F112-F180 AromaticContact CG-CE2 3.7Å; F112-F180 HydrophobicContact CG-CE2 3.7Å; F112-F180 AromaticContact CG-CZ 3.66Å; F112-F180 HydrophobicContact CG-CZ 3.66Å; F112-F180 HydrophobicContact CZ-CE1 4.41Å; F112-F180 HydrophobicContact CZ-CE2 4.14Å; F112-F180 AromaticContact CZ-CZ 3.84Å; F112-F180 HydrophobicContact CZ-CZ 3.84Å; A176-F180 HydrophobicContact CB-CD2 4.21Å; A176-F180 HydrophobicContact CB-CE2 4.34Å; A176-F180 WeakPolarHBondContact O-CB 3.41Å; A176-F180 WeakPolarHBondContact O-CD2 3.39Å; A176-F180 PolarHBondContact O-N 3.41Å
181	V	91.7	Very high	92.6	Very high	16 Å²	16	21.7 Å²	21.7	10%	0.097	11%	0.111	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-82.8	121.2	-179	179.9	0	0	0	0	109.1	Q66 I68 M177 L277	Q66-V181 CarbonylContact O-C 3.46Å; Q66-V181 WeakPolarHBondContact O-CA 3.28Å; I68-V181 HydrophobicContact CD1-CG1 3.26Å; I68-V181 HydrophobicContact CG1-CG1 3.69Å; M177-V181 WeakPolarHBondContact O-CB 3.41Å; M177-V181 WeakPolarHBondContact O-CG2 3.32Å; M177-V181 PolarHBondContact O-N 2.96Å; M177-V181 HydrophobicContact SD-CG2 4.07Å; V181-L277 HydrophobicContact CB-CD2 3.67Å; V181-L277 HydrophobicContact CG1-CD1 3.89Å; V181-L277 HydrophobicContact CG1-CD2 3.8Å; V181-L277 WeakPolarHBondContact O-CD2 3.46Å
182	R	89.2	Confident	92.7	Very high	19 Å²	19	19.1 Å²	19.1	7%	0.072	10%	0.099	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-119.8	132.7	-175.1	-65.5	-174	-176.1	-168.9	-15.9	111.9	S35 D39 I65 Q66 T67 I68	S35-R182 PolarHBondContact O-NH2 3.46Å; D39-R182 VanDerWaalsContact CG-NH2 3.32Å; D39-R182 IonicContact OD1-CZ 3.57Å; D39-R182 IonicContact OD1-NH1 2.91Å; D39-R182 PolarHBondContact OD1-NH1 2.6Å; D39-R182 IonicContact OD1-NH2 3.62Å; D39-R182 PolarHBondContact OD1-NH2 2.92Å; D39-R182 IonicContact OD2-CZ 2.58Å; D39-R182 IonicContact OD2-NH1 3.24Å; D39-R182 IonicContact OD2-NH2 2.97Å; I65-R182 VanDerWaalsContact CD1-CZ 3.45Å; I65-R182 HydrophobicContact CG2-CG 3.97Å; I65-R182 VanDerWaalsContact CG2-NE 3.32Å; Q66-R182 PolarHBondContact O-N 2.93Å; T67-R182 WeakPolarHBondContact CA-O 3.5Å; T67-R182 HydrophobicContact CG2-CB 4.25Å; I68-R182 PolarHBondContact N-O 2.84Å
183	L	91.3	Very high	92.8	Very high	4 Å²	4	19.2 Å²	19.2	2%	0.021	10%	0.099	C	C	.	.			trans	-91.6	126.6	171.7	-55.3	176.7	0	0	0	108.9	I68 V188 S189 L192 L277 F281	I68-L183 HydrophobicContact CB-CD2 4.15Å; I68-L183 HydrophobicContact CD1-CD2 4.07Å; L183-V188 HydrophobicContact CD2-CG1 4.31Å; L183-S189 WeakPolarHBondContact CD1-OG 3.39Å; L183-L192 HydrophobicContact CD2-CD2 3.93Å; L183-L277 HydrophobicContact CD1-CB 3.76Å; L183-L277 HydrophobicContact CG-CB 4.19Å; L183-F281 HydrophobicContact CB-CB 4.18Å; L183-F281 HydrophobicContact CB-CG 4.47Å; L183-F281 VanDerWaalsContact O-CD2 3.28Å; L183-F281 WeakPolarHBondContact O-CD2 3.27Å
184	P	89.2	Confident	92.8	Very high	45 Å²	45	20.9 Å²	20.9	29%	0.292	11%	0.112	S	C	.	.			trans	-78.1	-28.5	-176.2	29.7	-35.4	0	0	0	112.6	I68 V188 P371	I68-P184 WeakPolarHBondContact O-CD 3.35Å; I68-P184 WeakPolarHBondContact O-CG 3.39Å; P184-V188 HydrophobicContact CG-CB 4.22Å; P184-V188 HydrophobicContact CG-CG2 3.78Å; P184-P371 WeakPolarHBondContact O-CG 3.4Å
185	S	91.4	Very high	92.9	Very high	12 Å²	12	21.7 Å²	21.7	8%	0.084	12%	0.12	C	C	.	.	S	Bend	trans	-151.3	164.6	-176.3	69	0	0	0	0	113	K187 V188 S189 W368	S185-K187 PolarHBondContact O-N 2.91Å; S185-V188 PolarHBondContact O-N 3.23Å; S185-V188 PolarHBondContact OG-N 2.98Å; S185-S189 PolarHBondContact O-N 3.38Å; S185-S189 PolarHBondContact O-OG 2.89Å; S185-W368 WeakPolarHBondContact CB-O 3.19Å
186	L	93	Very high	92.8	Very high	0 Å²	0	22 Å²	22	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-62.9	-34.1	174.5	-172	73.6	0	0	0	111.1	V188 S189 C190 L278 F281 L354 L355 L364 M367 W368	L186-V188 PolarHBondContact O-N 3.49Å; L186-S189 WeakPolarHBondContact O-CB 3.34Å; L186-S189 PolarHBondContact O-N 2.89Å; L186-C190 PolarHBondContact O-N 2.85Å; L186-C190 PolarHBondContact O-SG 3.36Å; L186-C190 VanDerWaalsContact O-SG 3.33Å; L186-L278 HydrophobicContact CD1-CD1 4.42Å; L186-F281 HydrophobicContact CB-CE1 3.92Å; L186-F281 HydrophobicContact CB-CZ 4.28Å; L186-F281 HydrophobicContact CD1-CE1 4.09Å; L186-F281 VanDerWaalsContact N-CZ 3.31Å; L186-L354 HydrophobicContact CD1-CD2 3.37Å; L186-L354 HydrophobicContact CD1-CG 3.99Å; L186-L355 HydrophobicContact CD2-CD2 3.73Å; L186-L355 HydrophobicContact CG-CD2 4.49Å; L186-L364 HydrophobicContact CD2-CD1 3.81Å; L186-M367 HydrophobicContact CB-CB 4.42Å; L186-M367 HydrophobicContact CB-CG 4.02Å; L186-M367 WeakPolarHBondContact CB-O 3.17Å; L186-M367 HydrophobicContact CD1-CE 4.19Å; L186-M367 HydrophobicContact CD1-SD 4.09Å; L186-M367 HydrophobicContact CD2-CB 4.26Å; L186-M367 HydrophobicContact CD2-CG 4.21Å; L186-M367 HydrophobicContact CD2-SD 4.05Å; L186-M367 PolarHBondContact N-O 3.31Å; L186-W368 HydrophobicContact CD2-CE3 4.08Å; L186-W368 HydrophobicContact CG-CE3 4.38Å
187	K	93.3	Very high	92.8	Very high	104 Å²	104	23.5 Å²	23.5	45%	0.452	13%	0.129	S	C	.	.	H	α-helix	trans	-57.5	-49.2	175.9	179.9	-175.1	175.5	-175	0	111.5	S185 S189 C190 L191 W368	S185-K187 PolarHBondContact O-N 2.91Å; K187-S189 VanDerWaalsContact C-N 3.3Å; K187-S189 PolarHBondContact O-N 3.4Å; K187-C190 PolarHBondContact O-N 3.39Å; K187-L191 WeakPolarHBondContact O-CB 3.4Å; K187-L191 PolarHBondContact O-N 3.48Å; K187-W368 HydrophobicContact CB-CD2 4.09Å; K187-W368 HydrophobicContact CB-CG 4.33Å; K187-W368 HydrophobicContact CB-CZ2 4.17Å; K187-W368 WeakPolarHBondContact CB-O 3.47Å; K187-W368 HydrophobicContact CG-CZ2 3.99Å
188	V	93.5	Very high	92.9	Very high	7 Å²	7	26.1 Å²	26.1	4%	0.042	14%	0.143	C	C	.	.	H	α-helix	trans	-64.6	-39.2	179.3	179.5	0	0	0	0	110.6	I68 A73 L183 P184 S185 L186 L191 L192	I68-V188 HydrophobicContact CG2-CG1 4.05Å; A73-V188 HydrophobicContact CB-CG1 3.89Å; L183-V188 HydrophobicContact CD2-CG1 4.31Å; P184-V188 HydrophobicContact CG-CB 4.22Å; P184-V188 HydrophobicContact CG-CG2 3.78Å; S185-V188 PolarHBondContact O-N 3.23Å; S185-V188 PolarHBondContact OG-N 2.98Å; L186-V188 PolarHBondContact O-N 3.49Å; V188-L191 PolarHBondContact O-N 3Å; V188-L192 WeakPolarHBondContact O-CB 3.42Å; V188-L192 PolarHBondContact O-N 3.28Å
189	S	93.6	Very high	92.7	Very high	0 Å²	0	28.1 Å²	28.1	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-62.4	-45.7	177.1	-48.1	0	0	0	0	112.4	L183 S185 L186 K187 L192 L193 L278	L183-S189 WeakPolarHBondContact CD1-OG 3.39Å; S185-S189 PolarHBondContact O-N 3.38Å; S185-S189 PolarHBondContact O-OG 2.89Å; L186-S189 WeakPolarHBondContact O-CB 3.34Å; L186-S189 PolarHBondContact O-N 2.89Å; K187-S189 VanDerWaalsContact C-N 3.3Å; K187-S189 PolarHBondContact O-N 3.4Å; S189-L192 PolarHBondContact O-N 3.35Å; S189-L193 WeakPolarHBondContact O-CB 3.33Å; S189-L193 WeakPolarHBondContact O-CG 3.38Å; S189-L193 PolarHBondContact O-N 3.01Å; S189-L278 VanDerWaalsContact CB-CD1 3.49Å
190	C	94.2	Very high	92.6	Very high	16 Å²	16	28.4 Å²	28.4	11%	0.108	15%	0.152	C	C	.	.	H	α-helix	trans	-63.6	-42.1	175	-70.1	0	0	0	0	111.8	L186 K187 S194 W368	L186-C190 PolarHBondContact O-N 2.85Å; L186-C190 PolarHBondContact O-SG 3.36Å; L186-C190 VanDerWaalsContact O-SG 3.33Å; K187-C190 PolarHBondContact O-N 3.39Å; C190-S194 WeakPolarHBondContact O-CB 3.24Å; C190-S194 PolarHBondContact O-N 2.94Å; C190-S194 PolarHBondContact O-OG 3.23Å; C190-W368 HydrophobicContact CB-CH2 4.45Å; C190-W368 HydrophobicContact CB-CZ3 4.47Å
191	L	94.3	Very high	92.6	Very high	41 Å²	41	28.9 Å²	28.9	22%	0.215	16%	0.159	C	C	.	.	H	α-helix	trans	-62.2	-50.2	177.3	-165.1	174.8	0	0	0	110.5	A73 L74 K187 V188 L193 S194 G195	A73-L191 HydrophobicContact CB-CD2 4.14Å; L74-L191 HydrophobicContact CB-CD2 3.97Å; L74-L191 HydrophobicContact CD1-CD2 4.15Å; K187-L191 WeakPolarHBondContact O-CB 3.4Å; K187-L191 PolarHBondContact O-N 3.48Å; V188-L191 PolarHBondContact O-N 3Å; L191-L193 PolarHBondContact O-N 2.91Å; L191-S194 PolarHBondContact O-N 3.47Å; L191-S194 PolarHBondContact O-OG 3.17Å; L191-S194 VanDerWaalsContact O-OG 3.06Å; L191-G195 PolarHBondContact O-N 3.47Å
192	L	94.1	Very high	92.6	Very high	1 Å²	1	32.2 Å²	32.2	1%	0.005	17%	0.172	C	C	.	.	H	α-helix	trans	-56.5	-52.7	178.5	177.1	64.8	0	0	0	111.6	I68 A73 L76 L183 V188 S189 G195 L196 L277	I68-L192 HydrophobicContact CD1-CD2 4.46Å; A73-L192 HydrophobicContact CB-CB 4.18Å; L76-L192 HydrophobicContact CB-CD1 4.39Å; L76-L192 HydrophobicContact CD1-CD1 3.87Å; L76-L192 HydrophobicContact CD2-CD1 4.18Å; L76-L192 HydrophobicContact CG-CD1 4.39Å; L183-L192 HydrophobicContact CD2-CD2 3.93Å; V188-L192 WeakPolarHBondContact O-CB 3.42Å; V188-L192 PolarHBondContact O-N 3.28Å; S189-L192 PolarHBondContact O-N 3.35Å; L192-G195 PolarHBondContact O-N 3.32Å; L192-L196 HydrophobicContact CD1-CD1 3.96Å; L192-L196 HydrophobicContact CD1-CG 4.39Å; L192-L196 HydrophobicContact CG-CD1 4.06Å; L192-L196 WeakPolarHBondContact O-CB 3.46Å; L192-L196 VanDerWaalsContact O-CG 3.3Å; L192-L196 WeakPolarHBondContact O-CG 3.34Å; L192-L196 PolarHBondContact O-N 2.87Å; L192-L277 HydrophobicContact CD2-CD1 4.19Å
193	L	94.7	Very high	92.6	Very high	2 Å²	2	31.8 Å²	31.8	1%	0.01	17%	0.17	C	C	.	.	H	α-helix	trans	-68.5	-38.6	-177	-71.9	176.7	0	0	0	112.7	S189 L191 L197 M274 L278 V347 L351	S189-L193 WeakPolarHBondContact O-CB 3.33Å; S189-L193 WeakPolarHBondContact O-CG 3.38Å; S189-L193 PolarHBondContact O-N 3.01Å; L191-L193 PolarHBondContact O-N 2.91Å; L193-L197 VanDerWaalsContact O-CB 3.28Å; L193-L197 WeakPolarHBondContact O-CB 3.36Å; L193-L197 PolarHBondContact O-N 3.34Å; L193-M274 HydrophobicContact CD2-CB 4.07Å; L193-L278 HydrophobicContact CD1-CB 4.05Å; L193-L278 HydrophobicContact CD1-CD1 4.49Å; L193-L278 HydrophobicContact CD1-CD2 3.76Å; L193-L278 HydrophobicContact CD1-CG 4.31Å; L193-V347 HydrophobicContact CB-CG1 4.08Å; L193-V347 HydrophobicContact CB-CG2 4.04Å; L193-V347 HydrophobicContact CD2-CG2 4.3Å; L193-L351 HydrophobicContact CB-CD1 4.18Å; L193-L351 HydrophobicContact CD1-CD1 4.24Å; L193-L351 HydrophobicContact CD1-CD2 3.94Å; L193-L351 HydrophobicContact CD1-CG 4Å
194	S	93.8	Very high	92.3	Very high	52 Å²	52	32.8 Å²	32.8	36%	0.364	18%	0.177	S	C	.	.	H	α-helix	trans	-68.8	-38.1	175.3	60.2	0	0	0	0	112.3	C190 L191 L197 I198	C190-S194 WeakPolarHBondContact O-CB 3.24Å; C190-S194 PolarHBondContact O-N 2.94Å; C190-S194 PolarHBondContact O-OG 3.23Å; L191-S194 PolarHBondContact O-N 3.47Å; L191-S194 PolarHBondContact O-OG 3.17Å; L191-S194 VanDerWaalsContact O-OG 3.06Å; S194-L197 WeakPolarHBondContact O-CB 3.28Å; S194-L197 PolarHBondContact O-N 3.48Å; S194-I198 WeakPolarHBondContact O-CG1 3.47Å; S194-I198 PolarHBondContact O-N 2.83Å
195	G	94.3	Very high	92.3	Very high	17 Å²	17	36.5 Å²	36.5	18%	0.175	19%	0.188	C	C	.	.	H	α-helix	trans	-64.7	-41.8	174.2	0	0	0	0	0	112.4	P77 L191 L192 I198 Y199	P77-G195 VanDerWaalsContact CG-C 3.47Å; L191-G195 PolarHBondContact O-N 3.47Å; L192-G195 PolarHBondContact O-N 3.32Å; G195-I198 PolarHBondContact O-N 3.39Å; G195-Y199 WeakPolarHBondContact O-CB 3.29Å; G195-Y199 PolarHBondContact O-N 3.33Å
196	L	93.1	Very high	92.1	Very high	9 Å²	9	40.7 Å²	40.7	5%	0.047	21%	0.205	C	C	.	.	H	α-helix	trans	-67.7	-34.9	174.5	-74.5	171.9	0	0	0	113	L76 P77 L192 Y199 D200 M274 L343	L76-L196 HydrophobicContact CD2-CD1 4.44Å; L76-L196 HydrophobicContact CD2-CD2 3.63Å; L76-L196 HydrophobicContact CD2-CG 4.28Å; P77-L196 HydrophobicContact CG-CD2 4.17Å; P77-L196 HydrophobicContact CG-CG 4.22Å; L192-L196 HydrophobicContact CD1-CD1 3.96Å; L192-L196 HydrophobicContact CD1-CG 4.39Å; L192-L196 HydrophobicContact CG-CD1 4.06Å; L192-L196 WeakPolarHBondContact O-CB 3.46Å; L192-L196 VanDerWaalsContact O-CG 3.3Å; L192-L196 WeakPolarHBondContact O-CG 3.34Å; L192-L196 PolarHBondContact O-N 2.87Å; L196-Y199 WeakPolarHBondContact O-CB 3.02Å; L196-Y199 PolarHBondContact O-N 3.47Å; L196-D200 WeakPolarHBondContact O-CB 3.48Å; L196-D200 PolarHBondContact O-N 2.95Å; L196-M274 HydrophobicContact CD1-CB 3.93Å; L196-M274 HydrophobicContact CD1-CE 4.07Å; L196-M274 HydrophobicContact CD1-CG 3.53Å; L196-M274 HydrophobicContact CD1-SD 3.44Å; L196-M274 WeakPolarHBondContact CD1-SD 3.23Å; L196-L343 HydrophobicContact CB-CD1 3.99Å
197	L	93.9	Very high	91.9	Very high	40 Å²	40	40.8 Å²	40.8	21%	0.209	21%	0.206	C	C	.	.	H	α-helix	trans	-61	-47.8	172.1	172.7	63.9	0	0	0	111.4	L193 S194 Y199 D200 V201 L344 V347	L193-L197 VanDerWaalsContact O-CB 3.28Å; L193-L197 WeakPolarHBondContact O-CB 3.36Å; L193-L197 PolarHBondContact O-N 3.34Å; S194-L197 WeakPolarHBondContact O-CB 3.28Å; S194-L197 PolarHBondContact O-N 3.48Å; L197-Y199 VanDerWaalsContact C-N 3.3Å; L197-Y199 PolarHBondContact O-N 3.44Å; L197-D200 PolarHBondContact O-N 3.46Å; L197-V201 HydrophobicContact CD1-CG2 4.13Å; L197-V201 WeakPolarHBondContact O-CB 3.39Å; L197-V201 VanDerWaalsContact O-CG2 3.31Å; L197-V201 WeakPolarHBondContact O-CG2 3.31Å; L197-V201 PolarHBondContact O-N 3.31Å; L197-L344 VanDerWaalsContact CD1-CA 3.44Å; L197-L344 HydrophobicContact CD1-CB 4.15Å; L197-L344 HydrophobicContact CD1-CD1 3.79Å; L197-V347 HydrophobicContact CB-CG2 4.37Å; L197-V347 HydrophobicContact CD2-CG1 4.26Å
198	I	93.5	Very high	91.5	Very high	121 Å²	121	37.3 Å²	37.3	62%	0.621	20%	0.197	S	C	*	.	H	α-helix	trans	-60.9	-43.5	177.2	-67.8	164.8	0	0	0	110.2	S194 G195 F202	S194-I198 WeakPolarHBondContact O-CG1 3.47Å; S194-I198 PolarHBondContact O-N 2.83Å; G195-I198 PolarHBondContact O-N 3.39Å; I198-F202 WeakPolarHBondContact O-CB 3.1Å; I198-F202 PolarHBondContact O-N 3.06Å
199	Y	91.8	Very high	91.2	Very high	42 Å²	42	46 Å²	46	17%	0.165	23%	0.23	C	C	.	.	H	α-helix	trans	-55.7	-51.2	174.6	160.9	-90.4	0	0	0	112.1	A80 S81 L84 G195 L196 L197 F202 W203	A80-Y199 HydrophobicContact CB-CE2 4.08Å; S81-Y199 VanDerWaalsContact OG-CD2 3.3Å; S81-Y199 WeakPolarHBondContact OG-CD2 3.37Å; L84-Y199 HydrophobicContact CD1-CE2 4.48Å; L84-Y199 VanDerWaalsContact CD1-OH 3.25Å; L84-Y199 WeakPolarHBondContact CD1-OH 3.31Å; G195-Y199 WeakPolarHBondContact O-CB 3.29Å; G195-Y199 PolarHBondContact O-N 3.33Å; L196-Y199 WeakPolarHBondContact O-CB 3.02Å; L196-Y199 PolarHBondContact O-N 3.47Å; L197-Y199 VanDerWaalsContact C-N 3.3Å; L197-Y199 PolarHBondContact O-N 3.44Å; Y199-F202 PolarHBondContact O-N 2.91Å; Y199-W203 AromaticContact CD2-CD1 3.21Å; Y199-W203 HydrophobicContact CD2-CG 4.42Å; Y199-W203 AromaticContact CD2-NE1 3.47Å; Y199-W203 AromaticContact CE2-CD1 3.12Å; Y199-W203 HydrophobicContact CE2-CG 4.1Å; Y199-W203 AromaticContact CE2-NE1 3.3Å; Y199-W203 VanDerWaalsContact CE2-NE1 3.3Å; Y199-W203 AromaticContact CG-CD1 3.95Å; Y199-W203 AromaticContact CZ-CD1 3.8Å; Y199-W203 VanDerWaalsContact O-CD1 3.26Å; Y199-W203 PolarHBondContact O-N 3.46Å
200	D	89.7	Confident	90.9	Very high	6 Å²	6	50 Å²	50	3%	0.032	25%	0.251	C	S	.	.	H	α-helix	trans	-66.2	-44.4	-175.2	-161	19.1	0	0	0	110.8	L196 L197 F202 W203 V204 P341	L196-D200 WeakPolarHBondContact O-CB 3.48Å; L196-D200 PolarHBondContact O-N 2.95Å; L197-D200 PolarHBondContact O-N 3.46Å; D200-F202 VanDerWaalsContact C-N 3.34Å; D200-F202 PolarHBondContact O-N 2.82Å; D200-W203 PolarHBondContact O-N 2.84Å; D200-V204 VanDerWaalsContact O-CB 3.3Å; D200-V204 WeakPolarHBondContact O-CB 3.49Å; D200-V204 VanDerWaalsContact O-CG2 3.25Å; D200-V204 WeakPolarHBondContact O-CG2 3.25Å; D200-V204 PolarHBondContact O-N 3.14Å; D200-P341 HydrophobicContact CB-CB 4.22Å; D200-P341 VanDerWaalsContact OD2-CA 3.26Å; D200-P341 WeakPolarHBondContact OD2-CA 3.21Å; D200-P341 WeakPolarHBondContact OD2-CB 3.23Å
201	V	91	Very high	90.5	Very high	53 Å²	53	52.5 Å²	52.5	32%	0.321	26%	0.26	S	S	.	.	H	α-helix	trans	-60.7	-43.3	175.1	172.2	0	0	0	0	111.6	L197 F205 L344	L197-V201 HydrophobicContact CD1-CG2 4.13Å; L197-V201 WeakPolarHBondContact O-CB 3.39Å; L197-V201 VanDerWaalsContact O-CG2 3.31Å; L197-V201 WeakPolarHBondContact O-CG2 3.31Å; L197-V201 PolarHBondContact O-N 3.31Å; V201-F205 HydrophobicContact CG1-CD2 4.13Å; V201-F205 PolarHBondContact O-N 3.38Å; V201-L344 HydrophobicContact CG2-CD1 3.94Å
202	F	91.7	Very high	90	Very high	86 Å²	86	57.9 Å²	57.9	38%	0.377	29%	0.289	S	S	.	.	I	π-helix	trans	-63.9	-49.3	178.2	178	-90.9	0	0	0	111.7	I198 Y199 D200 F206 S207	I198-F202 WeakPolarHBondContact O-CB 3.1Å; I198-F202 PolarHBondContact O-N 3.06Å; Y199-F202 PolarHBondContact O-N 2.91Å; D200-F202 VanDerWaalsContact C-N 3.34Å; D200-F202 PolarHBondContact O-N 2.82Å; F202-F206 HydrophobicContact CD2-CB 4.13Å; F202-F206 AromaticContact CD2-CD1 3.68Å; F202-F206 HydrophobicContact CD2-CD1 3.68Å; F202-F206 HydrophobicContact CD2-CE1 4.44Å; F202-F206 HydrophobicContact CD2-CG 4.25Å; F202-F206 HydrophobicContact CE2-CB 4.49Å; F202-F206 AromaticContact CE2-CD1 3.23Å; F202-F206 HydrophobicContact CE2-CD1 3.23Å; F202-F206 AromaticContact CE2-CE1 3.71Å; F202-F206 HydrophobicContact CE2-CE1 3.71Å; F202-F206 HydrophobicContact CE2-CG 4.22Å; F202-F206 AromaticContact CZ-CD1 3.85Å; F202-F206 HydrophobicContact CZ-CD1 3.85Å; F202-F206 HydrophobicContact CZ-CE1 4.34Å; F202-F206 CarbonylContact O-C 3.57Å; F202-F206 WeakPolarHBondContact O-CA 3.2Å; F202-F206 VanDerWaalsContact O-CB 3.26Å; F202-F206 WeakPolarHBondContact O-CB 3.31Å; F202-F206 PolarHBondContact O-N 3.38Å; F202-S207 PolarHBondContact O-N 3.38Å
203	W	89.3	Confident	89.5	Confident	9 Å²	9	59.6 Å²	59.6	3%	0.034	30%	0.301	C	S	.	.	I	π-helix	trans	-76.4	-25	-175.5	-77.9	105.5	0	0	0	114.1	S81 L84 L85 Y199 D200 S207 V215 M216	S81-W203 PolarHBondContact OG-NE1 2.95Å; L84-W203 HydrophobicContact CD1-CD2 4.02Å; L84-W203 HydrophobicContact CD1-CE3 4.31Å; L84-W203 HydrophobicContact CD1-CG 4.21Å; L84-W203 HydrophobicContact CD2-CD2 4.47Å; L84-W203 HydrophobicContact CD2-CE3 4.06Å; L84-W203 HydrophobicContact CD2-CH2 4.12Å; L84-W203 HydrophobicContact CD2-CZ3 3.9Å; L85-W203 HydrophobicContact CB-CH2 4.25Å; Y199-W203 AromaticContact CD2-CD1 3.21Å; Y199-W203 HydrophobicContact CD2-CG 4.42Å; Y199-W203 AromaticContact CD2-NE1 3.47Å; Y199-W203 AromaticContact CE2-CD1 3.12Å; Y199-W203 HydrophobicContact CE2-CG 4.1Å; Y199-W203 AromaticContact CE2-NE1 3.3Å; Y199-W203 VanDerWaalsContact CE2-NE1 3.3Å; Y199-W203 AromaticContact CG-CD1 3.95Å; Y199-W203 AromaticContact CZ-CD1 3.8Å; Y199-W203 VanDerWaalsContact O-CD1 3.26Å; Y199-W203 PolarHBondContact O-N 3.46Å; D200-W203 PolarHBondContact O-N 2.84Å; W203-S207 WeakPolarHBondContact O-CB 3.32Å; W203-V215 HydrophobicContact CE3-CB 4.02Å; W203-V215 HydrophobicContact CE3-CG1 4.32Å; W203-V215 HydrophobicContact CZ3-CB 3.8Å; W203-V215 HydrophobicContact CZ3-CG1 3.78Å; W203-V215 HydrophobicContact CZ3-CG2 4.16Å; W203-M216 HydrophobicContact CB-CB 4.47Å
204	V	85.8	Confident	88.9	Confident	26 Å²	26	62.7 Å²	62.7	16%	0.158	32%	0.317	C	S	.	.	I	π-helix	trans	-82.9	-47.9	175.7	176.5	0	0	0	0	111.7	D200 N214 M216 P341	D200-V204 VanDerWaalsContact O-CB 3.3Å; D200-V204 WeakPolarHBondContact O-CB 3.49Å; D200-V204 VanDerWaalsContact O-CG2 3.25Å; D200-V204 WeakPolarHBondContact O-CG2 3.25Å; D200-V204 PolarHBondContact O-N 3.14Å; V204-N214 PolarHBondContact O-OD1 2.88Å; V204-N214 VanDerWaalsContact O-OD1 3.06Å; V204-M216 HydrophobicContact CG2-SD 3.66Å; V204-P341 HydrophobicContact CG2-CB 4.19Å
205	F	88	Confident	88.5	Confident	122 Å²	122	60.3 Å²	60.3	54%	0.535	30%	0.301	S	S	.	.	I	π-helix	trans	-96.2	-44.2	-173.3	-63.1	-67	0	0	0	113.6	V201 P341	V201-F205 HydrophobicContact CG1-CD2 4.13Å; V201-F205 PolarHBondContact O-N 3.38Å; F205-P341 HydrophobicContact CE2-CG 3.96Å; F205-P341 HydrophobicContact CZ-CG 4.33Å
206	F	88.4	Confident	87.8	Confident	101 Å²	101	62.5 Å²	62.5	44%	0.443	31%	0.307	S	S	.	.	I	π-helix	trans	-85.6	-34.1	-171.4	-165.8	-109.9	0	0	0	112.6	F202 A208 Y209 I210	F202-F206 HydrophobicContact CD2-CB 4.13Å; F202-F206 AromaticContact CD2-CD1 3.68Å; F202-F206 HydrophobicContact CD2-CD1 3.68Å; F202-F206 HydrophobicContact CD2-CE1 4.44Å; F202-F206 HydrophobicContact CD2-CG 4.25Å; F202-F206 HydrophobicContact CE2-CB 4.49Å; F202-F206 AromaticContact CE2-CD1 3.23Å; F202-F206 HydrophobicContact CE2-CD1 3.23Å; F202-F206 AromaticContact CE2-CE1 3.71Å; F202-F206 HydrophobicContact CE2-CE1 3.71Å; F202-F206 HydrophobicContact CE2-CG 4.22Å; F202-F206 AromaticContact CZ-CD1 3.85Å; F202-F206 HydrophobicContact CZ-CD1 3.85Å; F202-F206 HydrophobicContact CZ-CE1 4.34Å; F202-F206 CarbonylContact O-C 3.57Å; F202-F206 WeakPolarHBondContact O-CA 3.2Å; F202-F206 VanDerWaalsContact O-CB 3.26Å; F202-F206 WeakPolarHBondContact O-CB 3.31Å; F202-F206 PolarHBondContact O-N 3.38Å; F206-A208 PolarHBondContact O-N 3.22Å; F206-Y209 WeakPolarHBondContact O-CB 3.26Å; F206-Y209 PolarHBondContact O-N 2.67Å; F206-I210 HydrophobicContact CD1-CD1 3.48Å; F206-I210 VanDerWaalsContact CD1-CD1 3.48Å; F206-I210 HydrophobicContact CD1-CG1 4.27Å; F206-I210 HydrophobicContact CE1-CD1 3.13Å; F206-I210 HydrophobicContact CE1-CG1 4.02Å; F206-I210 HydrophobicContact CZ-CD1 3.87Å; F206-I210 HydrophobicContact CZ-CG1 4.39Å; F206-I210 PolarHBondContact O-N 2.71Å
207	S	87.9	Confident	87.2	Confident	1 Å²	1	65.6 Å²	65.6	1%	0.007	33%	0.326	C	S	.	.	H	α-helix	trans	-59.9	-34.6	175.3	-177.1	0	0	0	0	112.8	F202 W203 Y209 I210 F211 V215	F202-S207 PolarHBondContact O-N 3.38Å; W203-S207 WeakPolarHBondContact O-CB 3.32Å; S207-Y209 VanDerWaalsContact C-N 3.26Å; S207-Y209 PolarHBondContact O-N 2.9Å; S207-I210 PolarHBondContact O-N 3.34Å; S207-F211 WeakPolarHBondContact O-CB 3.11Å; S207-F211 PolarHBondContact O-N 3.45Å; S207-V215 WeakPolarHBondContact OG-CB 3.36Å; S207-V215 WeakPolarHBondContact OG-CG2 3.23Å
208	A	85.1	Confident	86.6	Confident	32 Å²	32	68.5 Å²	68.5	26%	0.264	34%	0.337	S	S	.	.	H	α-helix	trans	-61.4	-37.6	175.6	0	0	0	0	0	112	F206 N212 N214	F206-A208 PolarHBondContact O-N 3.22Å; A208-N212 VanDerWaalsContact O-CA 3.26Å; A208-N212 WeakPolarHBondContact O-CA 2.99Å; A208-N212 PolarHBondContact O-N 2.94Å; A208-N214 WeakPolarHBondContact CB-OD1 3.47Å
209	Y	87.2	Confident	86.1	Confident	190 Å²	190	63.3 Å²	63.3	75%	0.745	31%	0.311	S	S	*	.	H	α-helix	trans	-70.8	-41.3	179.7	-176.2	-103.6	0	0	0	112.1	F206 S207	F206-Y209 WeakPolarHBondContact O-CB 3.26Å; F206-Y209 PolarHBondContact O-N 2.67Å; S207-Y209 VanDerWaalsContact C-N 3.26Å; S207-Y209 PolarHBondContact O-N 2.9Å
210	I	87.7	Confident	85.3	Confident	83 Å²	83	63.4 Å²	63.4	43%	0.426	32%	0.321	S	S	.	.	H	α-helix	trans	-78.1	-48.5	-178.3	-64.9	172.6	0	0	0	112.2	F206 S207	F206-I210 HydrophobicContact CD1-CD1 3.48Å; F206-I210 VanDerWaalsContact CD1-CD1 3.48Å; F206-I210 HydrophobicContact CD1-CG1 4.27Å; F206-I210 HydrophobicContact CE1-CD1 3.13Å; F206-I210 HydrophobicContact CE1-CG1 4.02Å; F206-I210 HydrophobicContact CZ-CD1 3.87Å; F206-I210 HydrophobicContact CZ-CG1 4.39Å; F206-I210 PolarHBondContact O-N 2.71Å; S207-I210 PolarHBondContact O-N 3.34Å
211	F	85	Confident	84.7	Confident	68 Å²	68	67.5 Å²	67.5	30%	0.298	35%	0.346	S	S	.	.	H	α-helix	trans	-96.9	8.3	-170.2	-67.3	-81.5	0	0	0	113.3	F88 F89 S207 S213 V215	F88-F211 HydrophobicContact CE1-CD1 4.33Å; F89-F211 HydrophobicContact CZ-CE1 4.33Å; S207-F211 WeakPolarHBondContact O-CB 3.11Å; S207-F211 PolarHBondContact O-N 3.45Å; F211-S213 PolarHBondContact O-N 2.95Å; F211-S213 PolarHBondContact O-OG 3.32Å; F211-V215 HydrophobicContact CB-CG2 3.76Å; F211-V215 HydrophobicContact CD2-CG2 3.85Å; F211-V215 HydrophobicContact CG-CG2 3.81Å
212	N	83.9	Confident	84	Confident	154 Å²	154	67.8 Å²	67.8	82%	0.824	34%	0.344	S	S	*	.	S	Bend	trans	49.8	15.8	-171.7	-77	-82.1	0	0	0	113.9	A208	A208-N212 VanDerWaalsContact O-CA 3.26Å; A208-N212 WeakPolarHBondContact O-CA 2.99Å; A208-N212 PolarHBondContact O-N 2.94Å
213	S	83	Confident	83.2	Confident	37 Å²	37	67.1 Å²	67.1	26%	0.259	35%	0.348	S	S	.	.	S	Bend	trans	-157.5	145.2	-175.3	58.4	0	0	0	0	110	F211 V215	F211-S213 PolarHBondContact O-N 2.95Å; F211-S213 PolarHBondContact O-OG 3.32Å; S213-V215 PolarHBondContact O-N 2.93Å
214	N	83.3	Confident	82.5	Confident	68 Å²	68	66.7 Å²	66.7	36%	0.364	35%	0.346	S	S	.	.			trans	-74.3	93	173.9	-74.1	-62.5	0	0	0	109	V204 A208 M216 V217 K218	V204-N214 PolarHBondContact O-OD1 2.88Å; V204-N214 VanDerWaalsContact O-OD1 3.06Å; A208-N214 WeakPolarHBondContact CB-OD1 3.47Å; N214-M216 PolarHBondContact O-N 3.25Å; N214-V217 HydrophobicContact CB-CB 3.88Å; N214-V217 HydrophobicContact CB-CG2 3.87Å; N214-V217 PolarHBondContact O-N 3.06Å; N214-K218 PolarHBondContact O-N 3Å
215	V	84.3	Confident	82.2	Confident	2 Å²	2	66.5 Å²	66.5	1%	0.012	34%	0.344	C	S	.	.	H	α-helix	trans	-56.2	-41.2	-177	-178.1	0	0	0	0	110.5	L84 F88 W203 S207 F211 S213 V217 K218 V219	L84-V215 HydrophobicContact CD2-CB 4.07Å; L84-V215 HydrophobicContact CD2-CG1 3.13Å; F88-V215 HydrophobicContact CB-CG1 3.63Å; F88-V215 HydrophobicContact CD1-CG1 4.41Å; F88-V215 HydrophobicContact CD2-CB 4.13Å; F88-V215 HydrophobicContact CD2-CG1 3.4Å; F88-V215 VanDerWaalsContact CD2-CG1 3.4Å; F88-V215 HydrophobicContact CD2-CG2 4.08Å; F88-V215 HydrophobicContact CE2-CB 4.33Å; F88-V215 HydrophobicContact CE2-CG1 4.05Å; F88-V215 HydrophobicContact CE2-CG2 3.87Å; F88-V215 HydrophobicContact CG-CG1 3.58Å; F88-V215 HydrophobicContact CZ-CG2 4.19Å; W203-V215 HydrophobicContact CE3-CB 4.02Å; W203-V215 HydrophobicContact CE3-CG1 4.32Å; W203-V215 HydrophobicContact CZ3-CB 3.8Å; W203-V215 HydrophobicContact CZ3-CG1 3.78Å; W203-V215 HydrophobicContact CZ3-CG2 4.16Å; S207-V215 WeakPolarHBondContact OG-CB 3.36Å; S207-V215 WeakPolarHBondContact OG-CG2 3.23Å; F211-V215 HydrophobicContact CB-CG2 3.76Å; F211-V215 HydrophobicContact CD2-CG2 3.85Å; F211-V215 HydrophobicContact CG-CG2 3.81Å; S213-V215 PolarHBondContact O-N 2.93Å; V215-V217 PolarHBondContact O-N 3.45Å; V215-K218 PolarHBondContact O-N 3.34Å; V215-V219 HydrophobicContact CG1-CG2 4.45Å; V215-V219 WeakPolarHBondContact O-CB 3.49Å; V215-V219 WeakPolarHBondContact O-CG2 3.46Å; V215-V219 PolarHBondContact O-N 3.45Å
216	M	79.7	Confident	81.7	Confident	63 Å²	63	60.8 Å²	60.8	31%	0.31	32%	0.319	S	S	.	.	H	α-helix	trans	-59.3	-46.5	175.5	-176.3	-176.3	-176.7	0	0	112.5	L84 W203 V204 N214 A220	L84-M216 HydrophobicContact CD1-CB 4.39Å; W203-M216 HydrophobicContact CB-CB 4.47Å; V204-M216 HydrophobicContact CG2-SD 3.66Å; N214-M216 PolarHBondContact O-N 3.25Å; M216-A220 WeakPolarHBondContact O-CB 3.37Å; M216-A220 PolarHBondContact O-N 3.36Å
217	V	80.6	Confident	81.2	Confident	73 Å²	73	57 Å²	57	44%	0.442	31%	0.305	S	S	.	.	H	α-helix	trans	-70.7	-41.5	-179.4	178.6	0	0	0	0	110.6	N214 V215 A220 T221	N214-V217 HydrophobicContact CB-CB 3.88Å; N214-V217 HydrophobicContact CB-CG2 3.87Å; N214-V217 PolarHBondContact O-N 3.06Å; V215-V217 PolarHBondContact O-N 3.45Å; V217-A220 PolarHBondContact O-N 3.3Å; V217-T221 HydrophobicContact CG1-CG2 4.07Å; V217-T221 WeakPolarHBondContact O-CB 3.28Å; V217-T221 VanDerWaalsContact O-CG2 3.23Å; V217-T221 WeakPolarHBondContact O-CG2 3.46Å; V217-T221 PolarHBondContact O-N 2.91Å; V217-T221 PolarHBondContact O-OG1 3.02Å
218	K	82.7	Confident	80.8	Confident	101 Å²	101	59.6 Å²	59.6	44%	0.439	32%	0.319	S	S	.	.	H	α-helix	trans	-59.4	-52.9	179	-166.3	-177.2	-173.1	-180	0	110.8	F88 N214 V215 A220 T221 Q222	F88-K218 HydrophobicContact CD2-CD 4.18Å; F88-K218 HydrophobicContact CE2-CD 3.64Å; N214-K218 PolarHBondContact O-N 3Å; V215-K218 PolarHBondContact O-N 3.34Å; K218-A220 PolarHBondContact O-N 2.7Å; K218-T221 PolarHBondContact O-N 3.25Å; K218-T221 PolarHBondContact O-OG1 2.77Å; K218-Q222 VanDerWaalsContact O-CG 3.29Å; K218-Q222 WeakPolarHBondContact O-CG 3.41Å; K218-Q222 PolarHBondContact O-N 3.44Å; K218-Q222 PolarHBondContact O-OE1 3.42Å
219	V	83.1	Confident	80.5	Confident	13 Å²	13	59.5 Å²	59.5	8%	0.079	31%	0.314	C	S	.	.	H	α-helix	trans	-64.9	-40.8	179.8	173	0	0	0	0	111.6	L84 M87 F88 V215 T221	L84-V219 HydrophobicContact CD2-CG2 4.45Å; M87-V219 HydrophobicContact CB-CG1 4.18Å; M87-V219 HydrophobicContact CE-CG1 3.65Å; M87-V219 HydrophobicContact CG-CG1 3.53Å; M87-V219 HydrophobicContact SD-CG1 3.28Å; M87-V219 WeakPolarHBondContact SD-CG1 3.22Å; F88-V219 HydrophobicContact CB-CG2 4.07Å; F88-V219 HydrophobicContact CD2-CG2 4.32Å; V215-V219 HydrophobicContact CG1-CG2 4.45Å; V215-V219 WeakPolarHBondContact O-CB 3.49Å; V215-V219 WeakPolarHBondContact O-CG2 3.46Å; V215-V219 PolarHBondContact O-N 3.45Å; V219-T221 VanDerWaalsContact C-N 3.29Å; V219-T221 PolarHBondContact O-N 2.97Å
220	A	74.2	Confident	80.1	Confident	44 Å²	44	51.8 Å²	51.8	36%	0.364	29%	0.286	S	S	.	.	H	α-helix	trans	-74.2	-18.7	-176.8	0	0	0	0	0	113.5	M216 V217 K218 K253	M216-A220 WeakPolarHBondContact O-CB 3.37Å; M216-A220 PolarHBondContact O-N 3.36Å; V217-A220 PolarHBondContact O-N 3.3Å; K218-A220 PolarHBondContact O-N 2.7Å; A220-K253 VanDerWaalsContact C-NZ 3.34Å; A220-K253 VanDerWaalsContact CB-NZ 3.31Å; A220-K253 PolarHBondContact O-NZ 2.85Å
221	T	76.3	Confident	79.7	Confident	92 Å²	92	52 Å²	52	56%	0.564	29%	0.288	S	S	*	.	H	α-helix	trans	-96.9	-10.7	-180	52.8	0	0	0	0	113.2	V217 K218 V219	V217-T221 HydrophobicContact CG1-CG2 4.07Å; V217-T221 WeakPolarHBondContact O-CB 3.28Å; V217-T221 VanDerWaalsContact O-CG2 3.23Å; V217-T221 WeakPolarHBondContact O-CG2 3.46Å; V217-T221 PolarHBondContact O-N 2.91Å; V217-T221 PolarHBondContact O-OG1 3.02Å; K218-T221 PolarHBondContact O-N 3.25Å; K218-T221 PolarHBondContact O-OG1 2.77Å; V219-T221 VanDerWaalsContact C-N 3.29Å; V219-T221 PolarHBondContact O-N 2.97Å
222	Q	77.7	Confident	79.4	Confident	59 Å²	59	49.5 Å²	49.5	28%	0.276	28%	0.279	S	S	.	.	S	Bend	trans	-76.4	126.4	177.4	-73.9	172.5	-72	0	0	110.8	F91 K218	F91-Q222 HydrophobicContact CD2-CB 4.34Å; F91-Q222 HydrophobicContact CE1-CB 3.71Å; F91-Q222 HydrophobicContact CE1-CG 4.43Å; F91-Q222 HydrophobicContact CE2-CB 3.48Å; F91-Q222 VanDerWaalsContact CE2-CB 3.48Å; F91-Q222 HydrophobicContact CE2-CG 4.27Å; F91-Q222 HydrophobicContact CZ-CB 3.14Å; F91-Q222 HydrophobicContact CZ-CG 4.16Å; K218-Q222 VanDerWaalsContact O-CG 3.29Å; K218-Q222 WeakPolarHBondContact O-CG 3.41Å; K218-Q222 PolarHBondContact O-N 3.44Å; K218-Q222 PolarHBondContact O-OE1 3.42Å
223	P	75.1	Confident	79.1	Confident	72 Å²	72	48.7 Å²	48.7	47%	0.468	26%	0.264	S	S	.	.	P	Polyproline II helix	trans	-70.7	140.7	174.5	30.1	-33.7	0	0	0	109.9	R247	P223-R247 HydrophobicContact CB-CB 4.07Å
224	A	73.7	Confident	79.1	Confident	0 Å²	0	54.8 Å²	54.8	0%	0	29%	0.286	C	S	.	.	B	Isolated β-bridge	trans	-87.6	150.4	176.9	0	0	0	0	0	112.5	Q95 R247 L248 L250	Q95-A224 HydrophobicContact CB-CB 4.32Å; A224-R247 WeakPolarHBondContact O-CD 3.4Å; A224-L248 WeakPolarHBondContact CA-O 3.26Å; A224-L248 WeakPolarHBondContact CB-O 2.91Å; A224-L248 PolarHBondContact N-O 2.9Å; A224-L248 PolarHBondContact O-N 3.13Å; A224-L250 HydrophobicContact CB-CD1 3.49Å; A224-L250 VanDerWaalsContact CB-CD1 3.49Å
225	D	78.9	Confident	79	Confident	21 Å²	21	56.4 Å²	56.4	11%	0.112	29%	0.294	C	S	.	.	P	Polyproline II helix	trans	-70	139.3	168.5	-75.6	0.9	0	0	0	111.1	V230 R233 R247	D225-V230 HydrophobicContact CB-CG2 4.36Å; D225-R233 IonicContact OD2-NH2 4Å; D225-R233 PolarHBondContact OD2-NH2 3Å; D225-R247 WeakPolarHBondContact OD1-CD 3.36Å; D225-R247 IonicContact OD1-CZ 3.78Å; D225-R247 IonicContact OD1-NE 4Å; D225-R247 PolarHBondContact OD1-NE 2.89Å; D225-R247 IonicContact OD1-NH1 3.44Å; D225-R247 PolarHBondContact OD1-NH1 3.43Å; D225-R247 IonicContact OD1-NH2 2.79Å
226	N	78.7	Confident	78.6	Confident	2 Å²	2	64.4 Å²	64.4	1%	0.011	33%	0.331	C	S	.	.	P	Polyproline II helix	trans	-70.7	136.4	177.2	-66	-20.5	0	0	0	110.8	L228 D229 V230 V245 P246 L248	N226-L228 PolarHBondContact O-N 3.38Å; N226-D229 HydrophobicContact CB-CB 4.18Å; N226-D229 PolarHBondContact O-N 2.88Å; N226-D229 VanDerWaalsContact O-N 3.08Å; N226-V230 PolarHBondContact O-N 3.26Å; N226-V245 PolarHBondContact ND2-O 2.9Å; N226-P246 VanDerWaalsContact ND2-C 3.26Å; N226-P246 PolarHBondContact ND2-O 2.8Å; N226-P246 PolarHBondContact OD1-O 3.35Å; N226-L248 WeakPolarHBondContact OD1-CB 3.4Å; N226-L248 WeakPolarHBondContact OD1-CD1 3.46Å; N226-L248 WeakPolarHBondContact OD1-CG 3.34Å; N226-L248 PolarHBondContact OD1-N 3.21Å
227	P	77.2	Confident	78	Confident	23 Å²	23	66.2 Å²	66.2	15%	0.149	34%	0.342	C	S	.	.	H	α-helix	trans	-62.6	-29.7	176.7	25.4	-33.4	0	0	0	111.8	T99 I100 V158 L231	T99-P227 HydrophobicContact CG2-CG 4.23Å; I100-P227 HydrophobicContact CD1-CB 4.45Å; I100-P227 HydrophobicContact CG1-CB 3.86Å; V158-P227 HydrophobicContact CG1-CG 3.99Å; P227-L231 VanDerWaalsContact O-CB 3.31Å; P227-L231 WeakPolarHBondContact O-CB 3.39Å; P227-L231 PolarHBondContact O-N 3.08Å
228	L	78.8	Confident	77.2	Confident	54 Å²	54	64.8 Å²	64.8	28%	0.283	34%	0.341	S	S	.	.	H	α-helix	trans	-68.7	-36.5	174.8	-70.9	-179.4	0	0	0	113.1	V158 L159 N226 L231 S232	V158-L228 HydrophobicContact CB-CD1 4.02Å; V158-L228 HydrophobicContact CB-CG 4.45Å; V158-L228 HydrophobicContact CG1-CB 4.18Å; V158-L228 HydrophobicContact CG1-CD1 3.49Å; V158-L228 VanDerWaalsContact CG1-CD1 3.49Å; V158-L228 HydrophobicContact CG1-CG 3.51Å; L159-L228 HydrophobicContact CD2-CD1 3.45Å; L159-L228 VanDerWaalsContact CD2-CD1 3.45Å; L159-L228 HydrophobicContact CG-CD1 3.94Å; N226-L228 PolarHBondContact O-N 3.38Å; L228-L231 PolarHBondContact O-N 3.32Å; L228-S232 WeakPolarHBondContact O-CB 3.41Å; L228-S232 PolarHBondContact O-N 3.46Å; L228-S232 PolarHBondContact O-OG 3.13Å
229	D	78.5	Confident	76.1	Confident	30 Å²	30	65.1 Å²	65.1	16%	0.16	35%	0.354	C	S	.	.	H	α-helix	trans	-64.6	-47.6	175	172.1	52.4	0	0	0	110	N226 L231 S232 R233	N226-D229 HydrophobicContact CB-CB 4.18Å; N226-D229 PolarHBondContact O-N 2.88Å; N226-D229 VanDerWaalsContact O-N 3.08Å; D229-L231 VanDerWaalsContact C-N 3.31Å; D229-L231 PolarHBondContact O-N 3.47Å; D229-S232 PolarHBondContact O-N 2.92Å; D229-S232 PolarHBondContact O-OG 2.62Å; D229-R233 PolarHBondContact O-N 3.38Å; D229-R233 IonicContact OD1-NE 3.12Å; D229-R233 IonicContact OD2-CZ 3.99Å; D229-R233 IonicContact OD2-NE 2.92Å; D229-R233 PolarHBondContact OD2-NE 3.31Å; D229-R233 VanDerWaalsContact OD2-NE 3.12Å; D229-R233 IonicContact OD2-NH2 3.42Å; D229-R233 PolarHBondContact OD2-NH2 3.47Å
230	V	79.4	Confident	74.9	Confident	29 Å²	29	71.7 Å²	71.7	18%	0.176	39%	0.388	C	S	.	.	H	α-helix	trans	-60.7	-40.6	176.6	-179.7	0	0	0	0	111.7	V96 D225 N226 R233 K234	V96-V230 HydrophobicContact CG1-CG1 4.49Å; V96-V230 HydrophobicContact CG1-CG2 4.32Å; V96-V230 HydrophobicContact CG2-CG2 3.88Å; D225-V230 HydrophobicContact CB-CG2 4.36Å; N226-V230 PolarHBondContact O-N 3.26Å; V230-R233 PolarHBondContact O-N 2.95Å; V230-K234 WeakPolarHBondContact O-CG 3.35Å; V230-K234 PolarHBondContact O-N 3.38Å
231	L	79.2	Confident	74.2	Confident	87 Å²	87	74.9 Å²	74.9	46%	0.455	40%	0.403	S	S	.	.	H	α-helix	trans	-66.8	-42.7	177	-174.8	64.4	0	0	0	111.8	P227 L228 D229 R233 K234 L235	P227-L231 VanDerWaalsContact O-CB 3.31Å; P227-L231 WeakPolarHBondContact O-CB 3.39Å; P227-L231 PolarHBondContact O-N 3.08Å; L228-L231 PolarHBondContact O-N 3.32Å; D229-L231 VanDerWaalsContact C-N 3.31Å; D229-L231 PolarHBondContact O-N 3.47Å; L231-R233 VanDerWaalsContact C-N 3.34Å; L231-R233 PolarHBondContact O-N 3.32Å; L231-K234 PolarHBondContact O-N 3.48Å; L231-L235 HydrophobicContact CD1-CD1 3.76Å; L231-L235 HydrophobicContact CD1-CG 4.05Å; L231-L235 HydrophobicContact CD2-CD1 4.36Å; L231-L235 HydrophobicContact CG-CD1 3.76Å; L231-L235 HydrophobicContact CG-CG 4.35Å; L231-L235 WeakPolarHBondContact O-CB 3.24Å; L231-L235 WeakPolarHBondContact O-CG 3.48Å; L231-L235 PolarHBondContact O-N 2.86Å
232	S	79	Confident	73.1	Confident	16 Å²	16	71 Å²	71	11%	0.112	38%	0.382	C	S	.	.	H	α-helix	trans	-63	-39.7	176.1	68.7	0	0	0	0	112.2	L228 D229 L235 H236 L237	L228-S232 WeakPolarHBondContact O-CB 3.41Å; L228-S232 PolarHBondContact O-N 3.46Å; L228-S232 PolarHBondContact O-OG 3.13Å; D229-S232 PolarHBondContact O-N 2.92Å; D229-S232 PolarHBondContact O-OG 2.62Å; S232-L235 PolarHBondContact O-N 2.9Å; S232-H236 PolarHBondContact O-N 3.38Å; S232-H236 VanDerWaalsContact O-N 3.11Å; S232-L237 PolarHBondContact O-N 2.89Å
233	R	78	Confident	71.9	Confident	137 Å²	137	78.2 Å²	78.2	52%	0.517	41%	0.407	S	S	.	.	H	α-helix	trans	-62.2	-44	173.8	-77.1	-170.5	-83.9	155.2	-7.9	111.8	D225 D229 V230 L231 H236	D225-R233 IonicContact OD2-NH2 4Å; D225-R233 PolarHBondContact OD2-NH2 3Å; D229-R233 PolarHBondContact O-N 3.38Å; D229-R233 IonicContact OD1-NE 3.12Å; D229-R233 IonicContact OD2-CZ 3.99Å; D229-R233 IonicContact OD2-NE 2.92Å; D229-R233 PolarHBondContact OD2-NE 3.31Å; D229-R233 VanDerWaalsContact OD2-NE 3.12Å; D229-R233 IonicContact OD2-NH2 3.42Å; D229-R233 PolarHBondContact OD2-NH2 3.47Å; V230-R233 PolarHBondContact O-N 2.95Å; L231-R233 VanDerWaalsContact C-N 3.34Å; L231-R233 PolarHBondContact O-N 3.32Å; R233-H236 PolarHBondContact O-CD2 3.47Å
234	K	81.8	Confident	71.1	Confident	164 Å²	164	81.6 Å²	81.6	71%	0.713	42%	0.421	S	S	*	.	H	α-helix	trans	-69.5	-34.4	178	-76.4	-171.1	177.3	-168.3	0	113.6	V230 L231	V230-K234 WeakPolarHBondContact O-CG 3.35Å; V230-K234 PolarHBondContact O-N 3.38Å; L231-K234 PolarHBondContact O-N 3.48Å
235	L	81.4	Confident	70.4	Confident	102 Å²	102	82.9 Å²	82.9	53%	0.534	43%	0.429	S	S	.	.	T	Hydrogen-bonded Turn	trans	-88.9	1.4	-177.9	-71.5	178.7	0	0	0	113.7	L231 S232 L237	L231-L235 HydrophobicContact CD1-CD1 3.76Å; L231-L235 HydrophobicContact CD1-CG 4.05Å; L231-L235 HydrophobicContact CD2-CD1 4.36Å; L231-L235 HydrophobicContact CG-CD1 3.76Å; L231-L235 HydrophobicContact CG-CG 4.35Å; L231-L235 WeakPolarHBondContact O-CB 3.24Å; L231-L235 WeakPolarHBondContact O-CG 3.48Å; L231-L235 PolarHBondContact O-N 2.86Å; S232-L235 PolarHBondContact O-N 2.9Å; L235-L237 HydrophobicContact CB-CD1 3.6Å; L235-L237 HydrophobicContact CB-CG 4.2Å; L235-L237 HydrophobicContact CD1-CD1 3.77Å; L235-L237 HydrophobicContact CG-CD1 4.35Å; L235-L237 PolarHBondContact O-N 3.14Å
236	H	75.4	Confident	69.7	Low	170 Å²	170	84.5 Å²	84.5	79%	0.787	44%	0.44	S	S	*	.	T	Hydrogen-bonded Turn	trans	47.4	26.7	-175.1	-55.9	152.7	0	0	0	113.7	S232 R233 G238	S232-H236 PolarHBondContact O-N 3.38Å; S232-H236 VanDerWaalsContact O-N 3.11Å; R233-H236 PolarHBondContact O-CD2 3.47Å; H236-G238 PolarHBondContact O-N 3.4Å
237	L	68.2	Low	68.9	Low	102 Å²	102	91.6 Å²	91.6	53%	0.534	47%	0.467	S	S	.	.			trans	-66.8	122	172.1	-80.1	145.1	0	0	0	105.9	S232 L235	S232-L237 PolarHBondContact O-N 2.89Å; L235-L237 HydrophobicContact CB-CD1 3.6Å; L235-L237 HydrophobicContact CB-CG 4.2Å; L235-L237 HydrophobicContact CD1-CD1 3.77Å; L235-L237 HydrophobicContact CG-CD1 4.35Å; L235-L237 PolarHBondContact O-N 3.14Å
238	G	63.4	Low	68.1	Low	42 Å²	42	90.6 Å²	90.6	43%	0.433	46%	0.46	S	S	.	.			trans	-47.7	160.9	-160.7	0	0	0	0	0	116.1	H236 N240 V241	H236-G238 PolarHBondContact O-N 3.4Å; G238-N240 PolarHBondContact O-N 3.08Å; G238-V241 PolarHBondContact O-N 3.34Å; G238-V241 VanDerWaalsContact O-N 3.17Å
239	P	59.4	Low	67.4	Low	109 Å²	109	91 Å²	91	71%	0.708	47%	0.467	S	S	*	.	H	α-helix	trans	-57.6	-10.4	-166.2	21.6	-33.8	0	0	0	116.3
240	N	57.6	Low	66.5	Low	150 Å²	150	91.4 Å²	91.4	80%	0.802	47%	0.469	S	S	*	.	H	α-helix	trans	-89.1	-14.1	-177.7	-67.1	-5.7	0	0	0	114.5	G238	G238-N240 PolarHBondContact O-N 3.08Å
241	V	59.7	Low	65.5	Low	111 Å²	111	90.5 Å²	90.5	67%	0.673	47%	0.465	S	S	*	.	H	α-helix	trans	-91.9	-29.8	-178.6	-177.4	0	0	0	0	112.2	G238	G238-V241 PolarHBondContact O-N 3.34Å; G238-V241 VanDerWaalsContact O-N 3.17Å
242	G	54.6	Low	64.6	Low	12 Å²	12	88.1 Å²	88.1	12%	0.124	46%	0.461	C	S	.	.	H	α-helix	trans	-101.5	-10.8	-172.3	0	0	0	0	0	116.3	V245	G242-V245 WeakPolarHBondContact O-CG2 3.33Å
243	R	52.6	Low	64.2	Low	210 Å²	210	90.5 Å²	90.5	79%	0.792	47%	0.469	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.3	-22.8	-167.2	-143.7	173.7	88.7	113.8	0.3	115.2
244	D	56.8	Low	63.8	Low	142 Å²	142	84 Å²	84	76%	0.759	45%	0.445	S	S	*	.	T	Hydrogen-bonded Turn	trans	-107.3	12.8	-172	-62.7	-29.3	0	0	0	113.5	P246	D244-P246 WeakPolarHBondContact O-CD 3.16Å
245	V	60	Low	63.2	Low	28 Å²	28	77.9 Å²	77.9	17%	0.17	42%	0.421	C	S	.	.	P	Polyproline II helix	trans	-81.4	119.6	179.5	-130.7	0	0	0	0	110.2	V158 N226 G242	V158-V245 WeakPolarHBondContact O-CG1 3.43Å; N226-V245 PolarHBondContact ND2-O 2.9Å; G242-V245 WeakPolarHBondContact O-CG2 3.33Å
246	P	64.5	Low	62.5	Low	55 Å²	55	74.1 Å²	74.1	36%	0.357	40%	0.4	S	S	.	.	P	Polyproline II helix	trans	-71.5	131.2	-172.9	27.4	-36.1	0	0	0	112.4	T160 N226 D244 L248	T160-P246 WeakPolarHBondContact O-CG 3.42Å; N226-P246 VanDerWaalsContact ND2-C 3.26Å; N226-P246 PolarHBondContact ND2-O 2.8Å; N226-P246 PolarHBondContact OD1-O 3.35Å; D244-P246 WeakPolarHBondContact O-CD 3.16Å; P246-L248 WeakPolarHBondContact O-CD1 3.16Å; P246-L248 PolarHBondContact O-N 3.4Å
247	R	62.3	Low	61.8	Low	151 Å²	151	68.8 Å²	68.8	57%	0.57	38%	0.381	S	S	*	.	P	Polyproline II helix	trans	-51.8	122	179.4	-66.5	-70.6	178.2	97.4	4	111.6	P223 A224 D225 S249	P223-R247 HydrophobicContact CB-CB 4.07Å; A224-R247 WeakPolarHBondContact O-CD 3.4Å; D225-R247 WeakPolarHBondContact OD1-CD 3.36Å; D225-R247 IonicContact OD1-CZ 3.78Å; D225-R247 IonicContact OD1-NE 4Å; D225-R247 PolarHBondContact OD1-NE 2.89Å; D225-R247 IonicContact OD1-NH1 3.44Å; D225-R247 PolarHBondContact OD1-NH1 3.43Å; D225-R247 IonicContact OD1-NH2 2.79Å; R247-S249 PolarHBondContact O-N 3.17Å
248	L	59.7	Low	61.2	Low	1 Å²	1	64.4 Å²	64.4	1%	0.005	36%	0.358	C	S	.	.	B	Isolated β-bridge	trans	-72.3	121.4	179.2	-96	47.4	0	0	0	109.8	T99 W157 V158 M166 A224 N226 P246	T99-L248 HydrophobicContact CG2-CD2 4.11Å; W157-L248 HydrophobicContact CD2-CD2 4.44Å; W157-L248 HydrophobicContact CE3-CD2 4.23Å; W157-L248 HydrophobicContact CH2-CD2 3.33Å; W157-L248 HydrophobicContact CH2-CG 4.11Å; W157-L248 HydrophobicContact CZ2-CD2 3.57Å; W157-L248 HydrophobicContact CZ2-CG 3.82Å; W157-L248 HydrophobicContact CZ3-CD2 3.69Å; V158-L248 HydrophobicContact CG1-CD2 4.42Å; V158-L248 HydrophobicContact CG2-CD2 4.49Å; M166-L248 HydrophobicContact CE-CB 3.94Å; M166-L248 HydrophobicContact CE-CD1 3.82Å; M166-L248 HydrophobicContact CE-CG 3.46Å; M166-L248 VanDerWaalsContact CE-CG 3.46Å; A224-L248 WeakPolarHBondContact CA-O 3.26Å; A224-L248 WeakPolarHBondContact CB-O 2.91Å; A224-L248 PolarHBondContact N-O 2.9Å; A224-L248 PolarHBondContact O-N 3.13Å; N226-L248 WeakPolarHBondContact OD1-CB 3.4Å; N226-L248 WeakPolarHBondContact OD1-CD1 3.46Å; N226-L248 WeakPolarHBondContact OD1-CG 3.34Å; N226-L248 PolarHBondContact OD1-N 3.21Å; P246-L248 WeakPolarHBondContact O-CD1 3.16Å; P246-L248 PolarHBondContact O-N 3.4Å
249	S	63.2	Low	60.4	Low	62 Å²	62	67.9 Å²	67.9	43%	0.434	38%	0.376	S	S	.	.	P	Polyproline II helix	trans	-66	134.1	160.5	50.1	0	0	0	0	108.5	R247	R247-S249 PolarHBondContact O-N 3.17Å
250	L	60.5	Low	60	Low	39 Å²	39	68 Å²	68	20%	0.204	38%	0.375	C	S	.	.	P	Polyproline II helix	trans	-51.5	130	175.5	-92.7	75.3	0	0	0	109	M87 F98 A224 G252	M87-L250 HydrophobicContact CE-CD1 4.28Å; M87-L250 HydrophobicContact CE-CD2 3.76Å; F98-L250 HydrophobicContact CD1-CD2 3.4Å; F98-L250 HydrophobicContact CD1-CG 3.98Å; F98-L250 HydrophobicContact CE1-CD2 3.45Å; F98-L250 VanDerWaalsContact CE1-CD2 3.45Å; F98-L250 HydrophobicContact CE1-CG 4.17Å; F98-L250 HydrophobicContact CG-CD2 4.42Å; F98-L250 HydrophobicContact CZ-CD2 4.49Å; A224-L250 HydrophobicContact CB-CD1 3.49Å; A224-L250 VanDerWaalsContact CB-CD1 3.49Å; L250-G252 PolarHBondContact O-N 3.39Å
251	P	57.5	Low	59.7	Low	11 Å²	11	64.4 Å²	64.4	7%	0.071	37%	0.374	C	S	.	.	T	Hydrogen-bonded Turn	trans	-73.3	37.9	179.9	32.4	-39.1	0	0	0	112.3	T102 W157 I269	T102-P251 HydrophobicContact CG2-CB 4.32Å; T102-P251 HydrophobicContact CG2-CG 3.25Å; W157-P251 HydrophobicContact CH2-CG 4.47Å; W157-P251 HydrophobicContact CZ2-CG 4.45Å; P251-I269 WeakPolarHBondContact O-CD1 3.42Å
252	G	61.5	Low	59.4	Low	37 Å²	37	62.8 Å²	62.8	38%	0.381	37%	0.367	S	S	.	.	T	Hydrogen-bonded Turn	trans	-95.3	0.4	174.4	0	0	0	0	0	113.8	L250 I269	L250-G252 PolarHBondContact O-N 3.39Å; G252-I269 PolarHBondContact O-N 3.12Å; G252-I269 VanDerWaalsContact O-N 3.1Å
253	K	69.9	Low	59.4	Low	65 Å²	65	68.5 Å²	68.5	28%	0.283	39%	0.391	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-137.7	139.8	-175.6	-64.3	176.1	177	176.2	0	110.3	A220 L267	A220-K253 VanDerWaalsContact C-NZ 3.34Å; A220-K253 VanDerWaalsContact CB-NZ 3.31Å; A220-K253 PolarHBondContact O-NZ 2.85Å; K253-L267 WeakPolarHBondContact CA-O 3.43Å
254	L	69	Low	59.9	Low	1 Å²	1	64.7 Å²	64.7	1%	0.005	38%	0.38	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-87.8	132.4	165.5	-65.7	169.1	0	0	0	108.8	L27 D167 A170 M171 F256 M266 L267 I272	L27-L254 HydrophobicContact CD1-CD1 4.46Å; D167-L254 HydrophobicContact CB-CD2 4.34Å; A170-L254 HydrophobicContact CB-CD2 3.82Å; M171-L254 HydrophobicContact CG-CD2 3.92Å; L254-F256 HydrophobicContact CB-CD2 4.32Å; L254-F256 HydrophobicContact CB-CE2 3.64Å; L254-F256 HydrophobicContact CB-CZ 4.23Å; L254-F256 HydrophobicContact CD1-CE2 4.2Å; L254-F256 HydrophobicContact CD1-CZ 4.4Å; L254-F256 HydrophobicContact CG-CE2 4.44Å; L254-M266 WeakPolarHBondContact O-CA 3.41Å; L254-L267 PolarHBondContact N-O 3.32Å; L254-L267 PolarHBondContact O-N 2.9Å; L254-L267 VanDerWaalsContact O-N 3.13Å; L254-I272 HydrophobicContact CD1-CD1 3.53Å
255	V	69.6	Low	60.2	Low	35 Å²	35	58.7 Å²	58.7	21%	0.212	35%	0.349	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-123.2	99.1	-176.2	-177.5	0	0	0	0	110.1	D167 F264	D167-V255 PolarHBondContact OD1-N 2.93Å; D167-V255 VanDerWaalsContact OD2-O 3.07Å; V255-F264 HydrophobicContact CG1-CB 3.92Å; V255-F264 HydrophobicContact CG1-CD1 3.58Å; V255-F264 HydrophobicContact CG1-CE1 4.39Å; V255-F264 HydrophobicContact CG1-CG 3.96Å
256	F	66.6	Low	60.6	Low	24 Å²	24	63.1 Å²	63.1	11%	0.105	37%	0.37	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-94.8	125.1	177.1	-61.4	-82.2	0	0	0	110.9	T20 I23 L254 S258 F264 S265	T20-F256 HydrophobicContact CG2-CB 4.33Å; T20-F256 HydrophobicContact CG2-CD2 3.19Å; T20-F256 HydrophobicContact CG2-CE2 3.64Å; T20-F256 HydrophobicContact CG2-CG 3.96Å; I23-F256 HydrophobicContact CB-CZ 4.42Å; I23-F256 HydrophobicContact CD1-CD1 4.2Å; I23-F256 HydrophobicContact CD1-CE1 3.24Å; I23-F256 HydrophobicContact CD1-CE2 4.36Å; I23-F256 HydrophobicContact CD1-CZ 3.33Å; I23-F256 HydrophobicContact CG1-CZ 4.46Å; I23-F256 HydrophobicContact CG2-CZ 4.23Å; L254-F256 HydrophobicContact CB-CD2 4.32Å; L254-F256 HydrophobicContact CB-CE2 3.64Å; L254-F256 HydrophobicContact CB-CZ 4.23Å; L254-F256 HydrophobicContact CD1-CE2 4.2Å; L254-F256 HydrophobicContact CD1-CZ 4.4Å; L254-F256 HydrophobicContact CG-CE2 4.44Å; F256-S258 PolarHBondContact O-N 3.1Å; F256-F264 WeakPolarHBondContact O-CA 3.29Å; F256-S265 PolarHBondContact N-O 3.39Å; F256-S265 PolarHBondContact O-N 3.16Å
257	P	61.3	Low	61.2	Low	58 Å²	58	61.3 Å²	61.3	38%	0.377	36%	0.357	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-66.7	126.7	170.4	27.1	-32.4	0	0	0	109	W163 F264	W163-P257 HydrophobicContact CE3-CG 4.31Å; W163-P257 VanDerWaalsContact CH2-CD 3.42Å; W163-P257 HydrophobicContact CH2-CG 3.29Å; W163-P257 HydrophobicContact CZ2-CG 3.96Å; W163-P257 HydrophobicContact CZ3-CG 3.52Å; P257-F264 HydrophobicContact CB-CD1 4.35Å; P257-F264 HydrophobicContact CB-CE1 4.07Å
258	S	54.6	Low	62	Low	9 Å²	9	55.1 Å²	55.1	6%	0.063	34%	0.34	C	S	.	.	P	Polyproline II helix	trans	-73.8	143.1	169.9	-177.9	0	0	0	0	110.1	D14 F256 T260 G261 H263	D14-S258 PolarHBondContact OD1-OG 3.31Å; D14-S258 VanDerWaalsContact OD1-OG 3.13Å; D14-S258 PolarHBondContact OD2-OG 3.31Å; F256-S258 PolarHBondContact O-N 3.1Å; S258-T260 PolarHBondContact O-N 3.01Å; S258-G261 PolarHBondContact O-N 3.26Å; S258-H263 WeakPolarHBondContact CB-O 3.44Å; S258-H263 PolarHBondContact N-O 3.02Å; S258-H263 VanDerWaalsContact N-O 3.13Å
259	S	48.2	Very low	63.3	Low	115 Å²	115	55.7 Å²	55.7	80%	0.804	34%	0.343	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58	-16.8	177	-171.8	0	0	0	0	113.1
260	T	51.3	Low	64.4	Low	111 Å²	111	54.4 Å²	54.4	68%	0.681	34%	0.339	S	S	*	.	T	Hydrogen-bonded Turn	trans	-91.8	7	-179.3	-42.7	0	0	0	0	112.9	S258 S262	S258-T260 PolarHBondContact O-N 3.01Å; T260-S262 PolarHBondContact O-N 3Å
261	G	50.7	Low	65.8	Low	75 Å²	75	54 Å²	54	77%	0.773	34%	0.337	S	S	*	.	S	Bend	trans	72.3	-16.6	166.4	0	0	0	0	0	117.2	S258	S258-G261 PolarHBondContact O-N 3.26Å
262	S	53	Low	67.5	Low	77 Å²	77	53.5 Å²	53.5	54%	0.538	33%	0.334	S	S	.	.	S	Bend	trans	-105.2	-12.6	-175.4	72.7	0	0	0	0	115.7	T260	T260-S262 PolarHBondContact O-N 3Å
263	H	55.3	Low	69	Low	133 Å²	133	52.3 Å²	52.3	62%	0.616	32%	0.319	S	S	*	.			trans	-133.3	132.5	-175.3	-62.6	-64.3	0	0	0	112.3	S258	S258-H263 WeakPolarHBondContact CB-O 3.44Å; S258-H263 PolarHBondContact N-O 3.02Å; S258-H263 VanDerWaalsContact N-O 3.13Å
264	F	62.5	Low	70.1	Confident	129 Å²	129	50.9 Å²	50.9	57%	0.566	31%	0.314	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-94	128	168	-68.6	-81.4	0	0	0	109.1	V255 F256 P257 M266	V255-F264 HydrophobicContact CG1-CB 3.92Å; V255-F264 HydrophobicContact CG1-CD1 3.58Å; V255-F264 HydrophobicContact CG1-CE1 4.39Å; V255-F264 HydrophobicContact CG1-CG 3.96Å; F256-F264 WeakPolarHBondContact O-CA 3.29Å; P257-F264 HydrophobicContact CB-CD1 4.35Å; P257-F264 HydrophobicContact CB-CE1 4.07Å; F264-M266 HydrophobicContact CB-CE 4.34Å
265	S	63.6	Low	71.3	Confident	17 Å²	17	50.8 Å²	50.8	12%	0.119	31%	0.314	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-82	116.7	171.3	-167.4	0	0	0	0	108.1	T20 F256	T20-S265 WeakPolarHBondContact CG2-OG 3.46Å; F256-S265 PolarHBondContact N-O 3.39Å; F256-S265 PolarHBondContact O-N 3.16Å
266	M	69	Low	72.5	Confident	121 Å²	121	49.1 Å²	49.1	60%	0.596	30%	0.303	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-107	132.1	-178.3	-61.8	-174.9	-179.1	0	0	109.9	L254 F264	L254-M266 WeakPolarHBondContact O-CA 3.41Å; F264-M266 HydrophobicContact CB-CE 4.34Å
267	L	75.2	Confident	73.9	Confident	17 Å²	17	48.4 Å²	48.4	9%	0.089	30%	0.3	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-131.5	130.6	173.9	-172.1	62.9	0	0	0	110.5	S24 K253 L254 I272 L326	S24-L267 WeakPolarHBondContact OG-CD2 3.38Å; K253-L267 WeakPolarHBondContact CA-O 3.43Å; L254-L267 PolarHBondContact N-O 3.32Å; L254-L267 PolarHBondContact O-N 2.9Å; L254-L267 VanDerWaalsContact O-N 3.13Å; L267-I272 HydrophobicContact CD2-CD1 3.77Å; L267-I272 HydrophobicContact CD2-CG1 3.96Å; L267-I272 HydrophobicContact CG-CD1 4.26Å; L267-I272 HydrophobicContact CG-CG1 4.34Å; L267-L326 HydrophobicContact CD1-CD1 4.13Å
268	G	80.9	Confident	75.6	Confident	21 Å²	21	45.6 Å²	45.6	22%	0.216	28%	0.282	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-71.5	133.6	178.3	0	0	0	0	0	111.3	G270 D271	G268-G270 PolarHBondContact O-N 3.3Å; G268-D271 PolarHBondContact O-N 3.31Å; G268-D271 VanDerWaalsContact O-N 3.13Å
269	I	85.8	Confident	77.5	Confident	13 Å²	13	45.2 Å²	45.2	7%	0.067	28%	0.279	C	S	.	.	H	α-helix	trans	-62.6	-33.1	175.7	-65.3	174.3	0	0	0	110.8	A170 C174 P251 G252 D271 I272 V273	A170-I269 HydrophobicContact CB-CD1 3.52Å; A170-I269 HydrophobicContact CB-CG1 4.42Å; C174-I269 HydrophobicContact CB-CG2 4.24Å; P251-I269 WeakPolarHBondContact O-CD1 3.42Å; G252-I269 PolarHBondContact O-N 3.12Å; G252-I269 VanDerWaalsContact O-N 3.1Å; I269-D271 VanDerWaalsContact C-N 3.26Å; I269-D271 PolarHBondContact O-N 3.33Å; I269-I272 PolarHBondContact O-N 2.93Å; I269-I272 VanDerWaalsContact O-N 3.12Å; I269-V273 HydrophobicContact CG2-CG2 3.6Å; I269-V273 WeakPolarHBondContact O-CB 3.19Å; I269-V273 WeakPolarHBondContact O-CG2 3.2Å; I269-V273 PolarHBondContact O-N 2.9Å
270	G	87	Confident	79.8	Confident	34 Å²	34	39.9 Å²	39.9	35%	0.351	24%	0.242	S	C	.	.	H	α-helix	trans	-57.8	-37.2	174.8	0	0	0	0	0	113.1	G268 I272 M274	G268-G270 PolarHBondContact O-N 3.3Å; G270-I272 PolarHBondContact O-N 3.45Å; G270-M274 VanDerWaalsContact O-CB 3.29Å; G270-M274 WeakPolarHBondContact O-CB 3.22Å; G270-M274 WeakPolarHBondContact O-CG 3.31Å; G270-M274 PolarHBondContact O-N 3.47Å
271	D	89.5	Confident	81.9	Confident	31 Å²	31	34.7 Å²	34.7	17%	0.166	21%	0.21	C	C	.	.	H	α-helix	trans	-72.6	-16.3	-179.5	-55.3	-34.1	0	0	0	112.8	G268 I269 P275 Y322 A342 L346	G268-D271 PolarHBondContact O-N 3.31Å; G268-D271 VanDerWaalsContact O-N 3.13Å; I269-D271 VanDerWaalsContact C-N 3.26Å; I269-D271 PolarHBondContact O-N 3.33Å; D271-P275 VanDerWaalsContact O-CD 3.28Å; D271-P275 WeakPolarHBondContact O-CD 3.5Å; D271-P275 WeakPolarHBondContact O-CG 3.28Å; D271-Y322 PolarHBondContact O-OH 3.47Å; D271-A342 HydrophobicContact CB-CB 4.2Å; D271-L346 HydrophobicContact CB-CD1 4Å
272	I	92.4	Very high	83.9	Confident	0 Å²	0	31.1 Å²	31.1	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-95.3	-50	174	-53	173.2	0	0	0	109.7	S24 L27 I28 C174 L254 L267 I269 G270 G276	S24-I272 WeakPolarHBondContact OG-CD1 3.42Å; L27-I272 HydrophobicContact CB-CG2 4.4Å; L27-I272 HydrophobicContact CD1-CD1 4.37Å; I28-I272 HydrophobicContact CD1-CG2 4.11Å; I28-I272 HydrophobicContact CG1-CG2 3.82Å; C174-I272 VanDerWaalsContact SG-CG2 3.51Å; L254-I272 HydrophobicContact CD1-CD1 3.53Å; L267-I272 HydrophobicContact CD2-CD1 3.77Å; L267-I272 HydrophobicContact CD2-CG1 3.96Å; L267-I272 HydrophobicContact CG-CD1 4.26Å; L267-I272 HydrophobicContact CG-CG1 4.34Å; I269-I272 PolarHBondContact O-N 2.93Å; I269-I272 VanDerWaalsContact O-N 3.12Å; G270-I272 PolarHBondContact O-N 3.45Å; I272-G276 WeakPolarHBondContact O-CA 3.39Å; I272-G276 PolarHBondContact O-N 3.5Å
273	V	93.7	Very high	85.9	Confident	12 Å²	12	28 Å²	28	7%	0.073	15%	0.15	C	C	.	.	H	α-helix	trans	-64.8	-48	-175.4	173.6	0	0	0	0	110.8	C174 M177 I269 G276 L277	C174-V273 HydrophobicContact CB-CG2 4.05Å; C174-V273 VanDerWaalsContact SG-CG2 3.55Å; M177-V273 HydrophobicContact CB-CG1 3.87Å; M177-V273 HydrophobicContact CB-CG2 4.34Å; I269-V273 HydrophobicContact CG2-CG2 3.6Å; I269-V273 WeakPolarHBondContact O-CB 3.19Å; I269-V273 WeakPolarHBondContact O-CG2 3.2Å; I269-V273 PolarHBondContact O-N 2.9Å; V273-G276 CarbonylContact O-C 3.6Å; V273-G276 WeakPolarHBondContact O-CA 3.4Å; V273-G276 PolarHBondContact O-N 2.68Å; V273-L277 HydrophobicContact CG1-CD1 4.39Å; V273-L277 HydrophobicContact CG1-CG 4.29Å; V273-L277 WeakPolarHBondContact O-CG 3.44Å; V273-L277 PolarHBondContact O-N 3.02Å
274	M	92.6	Very high	87.6	Confident	35 Å²	35	23.1 Å²	23.1	17%	0.172	13%	0.127	C	C	.	.	H	α-helix	trans	-66.8	-48.9	-170.5	-58.6	-65.4	179.1	0	0	112.5	L76 L193 L196 G270 G276 L277	L76-M274 HydrophobicContact CD2-CE 4.27Å; L193-M274 HydrophobicContact CD2-CB 4.07Å; L196-M274 HydrophobicContact CD1-CB 3.93Å; L196-M274 HydrophobicContact CD1-CE 4.07Å; L196-M274 HydrophobicContact CD1-CG 3.53Å; L196-M274 HydrophobicContact CD1-SD 3.44Å; L196-M274 WeakPolarHBondContact CD1-SD 3.23Å; G270-M274 VanDerWaalsContact O-CB 3.29Å; G270-M274 WeakPolarHBondContact O-CB 3.22Å; G270-M274 WeakPolarHBondContact O-CG 3.31Å; G270-M274 PolarHBondContact O-N 3.47Å; M274-G276 VanDerWaalsContact C-N 3.28Å; M274-G276 PolarHBondContact O-N 3.06Å; M274-L277 PolarHBondContact O-N 3.08Å; M274-L277 HydrophobicContact SD-CD1 4.3Å
275	P	94.4	Very high	88.9	Confident	0 Å²	0	17 Å²	17	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-65.2	-32.5	168.4	-22.5	37.3	0	0	0	112.5	D271 L277 L278 L279 Y322 L343 L346	D271-P275 VanDerWaalsContact O-CD 3.28Å; D271-P275 WeakPolarHBondContact O-CD 3.5Å; D271-P275 WeakPolarHBondContact O-CG 3.28Å; P275-L277 VanDerWaalsContact C-N 3.3Å; P275-L277 PolarHBondContact O-N 2.98Å; P275-L278 WeakPolarHBondContact O-CB 3.34Å; P275-L278 PolarHBondContact O-N 2.91Å; P275-L278 VanDerWaalsContact O-N 3.14Å; P275-L279 WeakPolarHBondContact O-CD1 3.4Å; P275-L279 PolarHBondContact O-N 3.1Å; P275-Y322 HydrophobicContact CB-CD2 3.59Å; P275-Y322 HydrophobicContact CB-CE2 3.72Å; P275-Y322 HydrophobicContact CG-CD2 4.12Å; P275-Y322 HydrophobicContact CG-CE2 3.89Å; P275-L343 HydrophobicContact CG-CD2 4.38Å; P275-L346 HydrophobicContact CG-CB 4.28Å; P275-L346 HydrophobicContact CG-CD1 4.29Å
276	G	95.8	Very high	90.2	Very high	0 Å²	0	16.7 Å²	16.7	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-58.1	-38.3	174.8	0	0	0	0	0	113.6	I272 V273 M274 L279 C280	I272-G276 WeakPolarHBondContact O-CA 3.39Å; I272-G276 PolarHBondContact O-N 3.5Å; V273-G276 CarbonylContact O-C 3.6Å; V273-G276 WeakPolarHBondContact O-CA 3.4Å; V273-G276 PolarHBondContact O-N 2.68Å; M274-G276 VanDerWaalsContact C-N 3.28Å; M274-G276 PolarHBondContact O-N 3.06Å; G276-L279 PolarHBondContact O-N 3.13Å; G276-C280 VanDerWaalsContact O-CB 3.29Å; G276-C280 WeakPolarHBondContact O-CB 3.49Å; G276-C280 PolarHBondContact O-N 2.88Å
277	L	95.3	Very high	91.1	Very high	8 Å²	8	12.6 Å²	12.6	4%	0.042	8%	0.078	C	C	.	.	H	α-helix	trans	-64.1	-41.3	174.5	-65.4	176.8	0	0	0	111.8	V181 L183 L192 V273 M274 P275 C280 F281	V181-L277 HydrophobicContact CB-CD2 3.67Å; V181-L277 HydrophobicContact CG1-CD1 3.89Å; V181-L277 HydrophobicContact CG1-CD2 3.8Å; V181-L277 WeakPolarHBondContact O-CD2 3.46Å; L183-L277 HydrophobicContact CD1-CB 3.76Å; L183-L277 HydrophobicContact CG-CB 4.19Å; L192-L277 HydrophobicContact CD2-CD1 4.19Å; V273-L277 HydrophobicContact CG1-CD1 4.39Å; V273-L277 HydrophobicContact CG1-CG 4.29Å; V273-L277 WeakPolarHBondContact O-CG 3.44Å; V273-L277 PolarHBondContact O-N 3.02Å; M274-L277 PolarHBondContact O-N 3.08Å; M274-L277 HydrophobicContact SD-CD1 4.3Å; P275-L277 VanDerWaalsContact C-N 3.3Å; P275-L277 PolarHBondContact O-N 2.98Å; L277-C280 PolarHBondContact O-N 3.38Å; L277-F281 PolarHBondContact O-N 3.13Å
278	L	96.2	Very high	91.6	Very high	0 Å²	0	14 Å²	14	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-62	-47.5	173.2	176.2	73.8	0	0	0	110.7	L186 S189 L193 P275 C280 F281 V282 L351 L354	L186-L278 HydrophobicContact CD1-CD1 4.42Å; S189-L278 VanDerWaalsContact CB-CD1 3.49Å; L193-L278 HydrophobicContact CD1-CB 4.05Å; L193-L278 HydrophobicContact CD1-CD1 4.49Å; L193-L278 HydrophobicContact CD1-CD2 3.76Å; L193-L278 HydrophobicContact CD1-CG 4.31Å; P275-L278 WeakPolarHBondContact O-CB 3.34Å; P275-L278 PolarHBondContact O-N 2.91Å; P275-L278 VanDerWaalsContact O-N 3.14Å; L278-C280 VanDerWaalsContact C-N 3.33Å; L278-C280 PolarHBondContact O-N 2.95Å; L278-F281 WeakPolarHBondContact O-CB 3.43Å; L278-F281 PolarHBondContact O-N 3.4Å; L278-V282 HydrophobicContact CG-CG2 4.47Å; L278-V282 VanDerWaalsContact O-CG2 3.27Å; L278-V282 WeakPolarHBondContact O-CG2 3.42Å; L278-V282 PolarHBondContact O-N 2.91Å; L278-L351 HydrophobicContact CD1-CD2 4.05Å; L278-L351 HydrophobicContact CD2-CD2 3.8Å; L278-L351 HydrophobicContact CD2-CG 4.47Å; L278-L354 HydrophobicContact CD1-CD2 3.73Å; L278-L354 HydrophobicContact CD2-CD2 4.25Å; L278-L354 HydrophobicContact CG-CD2 4.19Å
279	L	96.2	Very high	91.8	Very high	0 Å²	0	14.7 Å²	14.7	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-63.7	-39.4	-179.8	-94.1	77.6	0	0	0	112.2	I28 P275 G276 V282 L283 F315 L319	I28-L279 HydrophobicContact CG2-CB 3.74Å; I28-L279 HydrophobicContact CG2-CD2 3.6Å; I28-L279 HydrophobicContact CG2-CG 4.27Å; P275-L279 WeakPolarHBondContact O-CD1 3.4Å; P275-L279 PolarHBondContact O-N 3.1Å; G276-L279 PolarHBondContact O-N 3.13Å; L279-V282 PolarHBondContact O-N 3.23Å; L279-L283 WeakPolarHBondContact O-CB 3.12Å; L279-L283 PolarHBondContact O-N 3.11Å; L279-F315 HydrophobicContact CB-CD2 4.31Å; L279-F315 HydrophobicContact CB-CE2 3.95Å; L279-F315 HydrophobicContact CD2-CE2 4.1Å; L279-F315 HydrophobicContact CG-CD2 4.46Å; L279-F315 HydrophobicContact CG-CE2 4.3Å; L279-F315 WeakPolarHBondContact O-CD2 3.26Å; L279-L319 HydrophobicContact CD2-CB 3.95Å; L279-L319 HydrophobicContact CD2-CD1 3.41Å; L279-L319 VanDerWaalsContact CD2-CD1 3.41Å; L279-L319 HydrophobicContact CD2-CG 4.31Å
280	C	95.2	Very high	91.7	Very high	3 Å²	3	20 Å²	20	2%	0.02	10%	0.102	C	C	.	.	H	α-helix	trans	-59.1	-47.7	173	-179.1	0	0	0	0	110.9	S32 S35 I178 G276 L277 L278 V282 L283 R284	S32-C280 WeakPolarHBondContact OG-CA 3.39Å; S32-C280 PolarHBondContact OG-N 3.39Å; S35-C280 WeakPolarHBondContact CB-SG 3.31Å; I178-C280 HydrophobicContact CG2-CB 3.97Å; G276-C280 VanDerWaalsContact O-CB 3.29Å; G276-C280 WeakPolarHBondContact O-CB 3.49Å; G276-C280 PolarHBondContact O-N 2.88Å; L277-C280 PolarHBondContact O-N 3.38Å; L278-C280 VanDerWaalsContact C-N 3.33Å; L278-C280 PolarHBondContact O-N 2.95Å; C280-V282 PolarHBondContact O-N 3.03Å; C280-L283 PolarHBondContact O-N 3.28Å; C280-R284 VanDerWaalsContact O-CG 3.26Å; C280-R284 WeakPolarHBondContact O-CG 3.45Å; C280-R284 PolarHBondContact O-N 3.38Å
281	F	94.8	Very high	91.4	Very high	2 Å²	2	21.8 Å²	21.8	1%	0.009	10%	0.101	C	C	.	.	H	α-helix	trans	-57.1	-47.1	174.2	167.8	-105.2	0	0	0	112.7	L183 L186 L277 L278 L283 R284 Y285 M367 P371 F372	L183-F281 HydrophobicContact CB-CB 4.18Å; L183-F281 HydrophobicContact CB-CG 4.47Å; L183-F281 VanDerWaalsContact O-CD2 3.28Å; L183-F281 WeakPolarHBondContact O-CD2 3.27Å; L186-F281 HydrophobicContact CB-CE1 3.92Å; L186-F281 HydrophobicContact CB-CZ 4.28Å; L186-F281 HydrophobicContact CD1-CE1 4.09Å; L186-F281 VanDerWaalsContact N-CZ 3.31Å; L277-F281 PolarHBondContact O-N 3.13Å; L278-F281 WeakPolarHBondContact O-CB 3.43Å; L278-F281 PolarHBondContact O-N 3.4Å; F281-L283 VanDerWaalsContact C-N 3.34Å; F281-L283 PolarHBondContact O-N 3.2Å; F281-R284 WeakPolarHBondContact O-CB 3.27Å; F281-R284 PolarHBondContact O-N 3.13Å; F281-Y285 PolarHBondContact O-N 3.12Å; F281-M367 HydrophobicContact CD1-CE 4.08Å; F281-M367 HydrophobicContact CE1-CE 3.46Å; F281-M367 VanDerWaalsContact CE1-CE 3.46Å; F281-M367 HydrophobicContact CE1-CG 4.01Å; F281-M367 HydrophobicContact CE1-SD 4.46Å; F281-M367 HydrophobicContact CZ-CE 4.24Å; F281-M367 HydrophobicContact CZ-CG 4.05Å; F281-P371 HydrophobicContact CE2-CB 4.17Å; F281-P371 HydrophobicContact CE2-CG 3.66Å; F281-P371 HydrophobicContact CZ-CB 4.11Å; F281-P371 HydrophobicContact CZ-CG 3.85Å; F281-F372 HydrophobicContact CD2-CE2 4.3Å; F281-F372 HydrophobicContact CD2-CZ 4.27Å; F281-F372 AromaticContact CE2-CE2 3.97Å; F281-F372 HydrophobicContact CE2-CE2 3.97Å; F281-F372 HydrophobicContact CE2-CZ 4.1Å
282	V	94.4	Very high	91	Very high	0 Å²	0	22.3 Å²	22.3	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-62.9	-41.5	179.6	175.4	0	0	0	0	111.4	L278 L279 C280 R284 Y285 D286 Y314 F315 T318 L354 M367	L278-V282 HydrophobicContact CG-CG2 4.47Å; L278-V282 VanDerWaalsContact O-CG2 3.27Å; L278-V282 WeakPolarHBondContact O-CG2 3.42Å; L278-V282 PolarHBondContact O-N 2.91Å; L279-V282 PolarHBondContact O-N 3.23Å; C280-V282 PolarHBondContact O-N 3.03Å; V282-R284 VanDerWaalsContact C-N 3.33Å; V282-R284 PolarHBondContact O-N 2.93Å; V282-Y285 WeakPolarHBondContact O-CB 3.29Å; V282-Y285 PolarHBondContact O-N 3.42Å; V282-D286 PolarHBondContact O-N 3.4Å; V282-Y314 VanDerWaalsContact CG1-C 3.42Å; V282-F315 HydrophobicContact CG1-CB 4.31Å; V282-F315 VanDerWaalsContact CG1-N 3.3Å; V282-T318 HydrophobicContact CG1-CG2 4.5Å; V282-T318 HydrophobicContact CG2-CG2 4.35Å; V282-L354 HydrophobicContact CG1-CD1 4.23Å; V282-L354 HydrophobicContact CG2-CD1 3.76Å; V282-L354 HydrophobicContact CG2-CD2 3.52Å; V282-L354 HydrophobicContact CG2-CG 4.3Å; V282-M367 HydrophobicContact CB-CE 4.49Å; V282-M367 HydrophobicContact CG2-CE 3.87Å
283	L	93.6	Very high	90.1	Very high	11 Å²	11	25.6 Å²	25.6	6%	0.058	13%	0.133	C	C	.	.	H	α-helix	trans	-63.9	-39.4	177.5	-167.2	69.9	0	0	0	111.6	S32 F33 L36 L279 C280 F281 D286 N287 F315	S32-L283 VanDerWaalsContact CB-CD2 3.5Å; F33-L283 HydrophobicContact CD1-CD2 4.23Å; F33-L283 HydrophobicContact CE1-CD2 4.36Å; F33-L283 HydrophobicContact CG-CD2 4.36Å; L36-L283 HydrophobicContact CD1-CD2 3.34Å; L36-L283 HydrophobicContact CD1-CG 3.62Å; L36-L283 HydrophobicContact CG-CD2 4.16Å; L36-L283 HydrophobicContact CG-CG 4.46Å; L279-L283 WeakPolarHBondContact O-CB 3.12Å; L279-L283 PolarHBondContact O-N 3.11Å; C280-L283 PolarHBondContact O-N 3.28Å; F281-L283 VanDerWaalsContact C-N 3.34Å; F281-L283 PolarHBondContact O-N 3.2Å; L283-D286 PolarHBondContact O-N 2.97Å; L283-N287 PolarHBondContact O-N 3.33Å; L283-N287 VanDerWaalsContact O-N 3.08Å; L283-N287 PolarHBondContact O-ND2 3.29Å; L283-F315 HydrophobicContact CB-CB 4.45Å; L283-F315 HydrophobicContact CB-CD2 3.58Å; L283-F315 HydrophobicContact CB-CE2 4Å; L283-F315 HydrophobicContact CB-CG 4.16Å; L283-F315 HydrophobicContact CD1-CB 3.76Å; L283-F315 HydrophobicContact CD1-CD1 3.73Å; L283-F315 HydrophobicContact CD1-CD2 3.71Å; L283-F315 HydrophobicContact CD1-CE1 4.2Å; L283-F315 HydrophobicContact CD1-CE2 4.16Å; L283-F315 HydrophobicContact CD1-CG 3.45Å; L283-F315 VanDerWaalsContact CD1-CG 3.45Å; L283-F315 HydrophobicContact CD1-CZ 4.39Å; L283-F315 HydrophobicContact CD2-CE2 4.28Å; L283-F315 HydrophobicContact CG-CD2 4.08Å; L283-F315 HydrophobicContact CG-CE2 4.34Å; L283-F315 HydrophobicContact CG-CG 4.3Å
284	R	90.9	Very high	88.7	Confident	31 Å²	31	28 Å²	28	12%	0.117	16%	0.16	C	C	.	.	H	α-helix	trans	-62.8	-43.5	173.2	-66.1	173.2	79.4	-145.4	-1	111.8	L36 D39 C280 F281 V282 N287 Y288 F372	L36-R284 HydrophobicContact CD2-CB 4.18Å; L36-R284 HydrophobicContact CD2-CG 3.57Å; L36-R284 HydrophobicContact CG-CG 4.26Å; D39-R284 IonicContact OD1-NH2 3.22Å; D39-R284 PolarHBondContact OD1-NH2 3.14Å; D39-R284 IonicContact OD2-CZ 2.65Å; D39-R284 IonicContact OD2-NE 3.35Å; D39-R284 PolarHBondContact OD2-NE 2.85Å; D39-R284 IonicContact OD2-NH2 3.72Å; D39-R284 PolarHBondContact OD2-NH2 3.02Å; C280-R284 VanDerWaalsContact O-CG 3.26Å; C280-R284 WeakPolarHBondContact O-CG 3.45Å; C280-R284 PolarHBondContact O-N 3.38Å; F281-R284 WeakPolarHBondContact O-CB 3.27Å; F281-R284 PolarHBondContact O-N 3.13Å; V282-R284 VanDerWaalsContact C-N 3.33Å; V282-R284 PolarHBondContact O-N 2.93Å; R284-N287 PolarHBondContact O-N 3.49Å; R284-Y288 WeakPolarHBondContact O-CB 3.49Å; R284-Y288 PolarHBondContact O-N 3.03Å; R284-F372 HydrophobicContact CB-CE1 4.15Å; R284-F372 HydrophobicContact CB-CZ 3.98Å
285	Y	91	Very high	86.9	Confident	0 Å²	0	33 Å²	33	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-62.8	-43.7	175.8	-173.7	-102.8	0	0	0	112.8	F281 V282 N287 Y288 K289 Y314 M367 P371	F281-Y285 PolarHBondContact O-N 3.12Å; V282-Y285 WeakPolarHBondContact O-CB 3.29Å; V282-Y285 PolarHBondContact O-N 3.42Å; Y285-N287 PolarHBondContact O-N 3.05Å; Y285-Y288 PolarHBondContact O-N 3.39Å; Y285-K289 WeakPolarHBondContact O-CB 3.34Å; Y285-K289 PolarHBondContact O-N 2.96Å; Y285-Y314 HydrophobicContact CD1-CD2 4.15Å; Y285-Y314 HydrophobicContact CD1-CE2 4.18Å; Y285-Y314 HydrophobicContact CE1-CD2 4.36Å; Y285-Y314 AromaticContact CE1-CE2 3.92Å; Y285-Y314 HydrophobicContact CE1-CE2 3.92Å; Y285-M367 HydrophobicContact CD1-CE 4.01Å; Y285-M367 HydrophobicContact CD1-CG 4.34Å; Y285-M367 HydrophobicContact CD1-SD 4.31Å; Y285-M367 HydrophobicContact CD2-CG 4.32Å; Y285-M367 HydrophobicContact CE1-CG 4.32Å; Y285-M367 HydrophobicContact CE1-SD 4.43Å; Y285-M367 HydrophobicContact CE2-CB 4.46Å; Y285-M367 HydrophobicContact CE2-CG 4.29Å; Y285-M367 HydrophobicContact CG-CE 4.15Å; Y285-M367 HydrophobicContact CG-CG 4.33Å; Y285-P371 HydrophobicContact CD2-CB 3.55Å; Y285-P371 HydrophobicContact CE2-CB 3.81Å
286	D	90.8	Very high	84.6	Confident	11 Å²	11	37 Å²	37	6%	0.059	22%	0.216	C	C	.	.	H	α-helix	trans	-57.8	-46.1	175.2	-90.8	-37	0	0	0	111.7	V282 L283 K289 K290 S313 Y314 F315	V282-D286 PolarHBondContact O-N 3.4Å; L283-D286 PolarHBondContact O-N 2.97Å; D286-K289 PolarHBondContact O-N 3.34Å; D286-K290 WeakPolarHBondContact O-CG 3.41Å; D286-K290 PolarHBondContact O-N 3.38Å; D286-S313 WeakPolarHBondContact OD2-CB 3.42Å; D286-Y314 WeakPolarHBondContact OD1-CD2 3.33Å; D286-Y314 PolarHBondContact OD1-N 3.01Å; D286-Y314 VanDerWaalsContact OD1-N 3.14Å; D286-Y314 PolarHBondContact OD2-N 3.45Å; D286-F315 WeakPolarHBondContact OD2-CB 3.46Å; D286-F315 PolarHBondContact OD2-N 2.9Å
287	N	87.1	Confident	81.9	Confident	36 Å²	36	43 Å²	43	19%	0.193	26%	0.256	C	S	.	.	H	α-helix	trans	-66.3	-43.4	178.4	-79	-75.1	0	0	0	112.3	L36 L283 R284 Y285 K289 K290 Q291	L36-N287 WeakPolarHBondContact CD1-ND2 3.44Å; L36-N287 HydrophobicContact CD2-CB 4.22Å; L283-N287 PolarHBondContact O-N 3.33Å; L283-N287 VanDerWaalsContact O-N 3.08Å; L283-N287 PolarHBondContact O-ND2 3.29Å; R284-N287 PolarHBondContact O-N 3.49Å; Y285-N287 PolarHBondContact O-N 3.05Å; N287-K289 VanDerWaalsContact C-N 3.31Å; N287-K289 PolarHBondContact O-N 2.86Å; N287-K290 WeakPolarHBondContact O-CB 3.09Å; N287-K290 PolarHBondContact O-N 3.49Å; N287-Q291 WeakPolarHBondContact O-CG 3.48Å; N287-Q291 PolarHBondContact O-N 3.35Å
288	Y	86.2	Confident	79.6	Confident	45 Å²	45	46.5 Å²	46.5	18%	0.176	29%	0.294	C	S	.	.	H	α-helix	trans	-58.3	-43.9	175.5	177.2	-111.7	0	0	0	111.9	R284 Y285 K290 Q291 A292 P371 F372 H373 S374	R284-Y288 WeakPolarHBondContact O-CB 3.49Å; R284-Y288 PolarHBondContact O-N 3.03Å; Y285-Y288 PolarHBondContact O-N 3.39Å; Y288-K290 PolarHBondContact O-N 3.06Å; Y288-Q291 PolarHBondContact O-N 3.39Å; Y288-A292 WeakPolarHBondContact O-CB 3.3Å; Y288-A292 PolarHBondContact O-N 2.99Å; Y288-P371 WeakPolarHBondContact CD1-O 3.08Å; Y288-P371 WeakPolarHBondContact CE1-O 3.49Å; Y288-F372 HydrophobicContact CD1-CD1 4.28Å; Y288-F372 HydrophobicContact CD2-CD1 4.47Å; Y288-F372 HydrophobicContact CG-CD1 4.06Å; Y288-H373 PolarHBondContact OH-O 2.83Å; Y288-S374 PolarHBondContact OH-N 3.46Å
289	K	84.5	Confident	77	Confident	36 Å²	36	50.7 Å²	50.7	16%	0.157	33%	0.328	C	S	.	.	H	α-helix	trans	-64.9	-38	176.9	-174.9	173	174.3	170.2	0	112.5	Y285 D286 N287 S293 D363	Y285-K289 WeakPolarHBondContact O-CB 3.34Å; Y285-K289 PolarHBondContact O-N 2.96Å; D286-K289 PolarHBondContact O-N 3.34Å; N287-K289 VanDerWaalsContact C-N 3.31Å; N287-K289 PolarHBondContact O-N 2.86Å; K289-S293 WeakPolarHBondContact O-CB 3.42Å; K289-S293 PolarHBondContact O-N 3.01Å; K289-S293 PolarHBondContact O-OG 3.19Å; K289-D363 IonicContact NZ-OD2 2.6Å; K289-D363 PolarHBondContact NZ-OD2 2.9Å
290	K	84.2	Confident	74.4	Confident	125 Å²	125	57 Å²	57	54%	0.543	37%	0.37	S	S	.	.	H	α-helix	trans	-63.1	-44.3	175.1	-75	174.5	-177	179.1	0	111.7	D286 N287 Y288 S293 G294	D286-K290 WeakPolarHBondContact O-CG 3.41Å; D286-K290 PolarHBondContact O-N 3.38Å; N287-K290 WeakPolarHBondContact O-CB 3.09Å; N287-K290 PolarHBondContact O-N 3.49Å; Y288-K290 PolarHBondContact O-N 3.06Å; K290-S293 PolarHBondContact O-N 3.36Å; K290-G294 PolarHBondContact O-N 2.88Å
291	Q	81.4	Confident	71.8	Confident	71 Å²	71	59.7 Å²	59.7	33%	0.332	40%	0.398	S	S	.	.	H	α-helix	trans	-63	-50	176.5	-68.7	169.3	24.6	0	0	111.2	F40 N287 Y288 S293 G294 D295	F40-Q291 VanDerWaalsContact CE1-NE2 3.27Å; N287-Q291 WeakPolarHBondContact O-CG 3.48Å; N287-Q291 PolarHBondContact O-N 3.35Å; Y288-Q291 PolarHBondContact O-N 3.39Å; Q291-S293 PolarHBondContact O-N 3.26Å; Q291-S293 VanDerWaalsContact O-N 3.16Å; Q291-G294 PolarHBondContact O-N 3.38Å; Q291-D295 PolarHBondContact O-N 3.41Å; Q291-D295 VanDerWaalsContact O-N 3.13Å
292	A	79.5	Confident	69.3	Low	42 Å²	42	65.1 Å²	65.1	35%	0.347	43%	0.433	S	S	.	.	H	α-helix	trans	-61.2	-28.6	179.1	0	0	0	0	0	113.9	Y288	Y288-A292 WeakPolarHBondContact O-CB 3.3Å; Y288-A292 PolarHBondContact O-N 2.99Å
293	S	73.3	Confident	66.9	Low	70 Å²	70	70.2 Å²	70.2	49%	0.49	48%	0.475	S	S	.	.	H	α-helix	trans	-83.9	-31.3	175.6	-50.4	0	0	0	0	112.2	K289 K290 Q291 S296	K289-S293 WeakPolarHBondContact O-CB 3.42Å; K289-S293 PolarHBondContact O-N 3.01Å; K289-S293 PolarHBondContact O-OG 3.19Å; K290-S293 PolarHBondContact O-N 3.36Å; Q291-S293 PolarHBondContact O-N 3.26Å; Q291-S293 VanDerWaalsContact O-N 3.16Å; S293-S296 PolarHBondContact O-N 2.77Å
294	G	64.7	Low	64.1	Low	63 Å²	63	75.2 Å²	75.2	65%	0.649	50%	0.502	S	S	*	.	H	α-helix	trans	-71	-32.1	179.5	0	0	0	0	0	113.9	K290 Q291 S296	K290-G294 PolarHBondContact O-N 2.88Å; Q291-G294 PolarHBondContact O-N 3.38Å; G294-S296 PolarHBondContact O-N 3.14Å
295	D	56.3	Low	62.2	Low	138 Å²	138	80.9 Å²	80.9	74%	0.738	53%	0.533	S	S	*	.	S	Bend	trans	-70.2	-17.6	174.4	-69.1	-24.4	0	0	0	112.8	Q291 C297	Q291-D295 PolarHBondContact O-N 3.41Å; Q291-D295 VanDerWaalsContact O-N 3.13Å; D295-C297 PolarHBondContact O-N 3.27Å; D295-C297 VanDerWaalsContact O-N 3.15Å
296	S	46.2	Very low	60.1	Low	86 Å²	86	84.7 Å²	84.7	60%	0.601	56%	0.56	S	S	*	*	S	Bend	trans	-80.4	96.4	172.9	-59.6	0	0	0	0	109.1	S293 G294 G298	S293-S296 PolarHBondContact O-N 2.77Å; G294-S296 PolarHBondContact O-N 3.14Å; S296-G298 PolarHBondContact O-N 3Å
297	C	37.8	Very low	58.1	Low	125 Å²	125	85.8 Å²	85.8	85%	0.845	57%	0.573	S	S	*	*			trans	-40.6	123.9	173.1	-70.8	0	0	0	0	112.5	D295	D295-C297 PolarHBondContact O-N 3.27Å; D295-C297 VanDerWaalsContact O-N 3.15Å
298	G	48.1	Very low	56.2	Low	82 Å²	82	94 Å²	94	85%	0.845	60%	0.602	S	S	*	*			trans	32.8	88.8	154.6	0	0	0	0	0	118.8	S296	S296-G298 PolarHBondContact O-N 3Å
299	A	40.2	Very low	54.2	Low	87 Å²	87	96 Å²	96	72%	0.719	61%	0.614	S	S	*	*			trans	-150.8	102.3	146.7	0	0	0	0	0	110	G301	A299-G301 PolarHBondContact O-N 3.4Å
300	P	41.5	Very low	52.8	Low	133 Å²	133	100.3 Å²	100.3	86%	0.864	64%	0.635	S	S	*	*			trans	-70.3	85.2	164.4	28.9	-29	0	0	0	107.9
301	G	41.8	Very low	51.4	Low	59 Å²	59	103 Å²	103	61%	0.608	65%	0.646	S	S	*	*			trans	-61.1	144.4	170	0	0	0	0	0	110.4	A299	A299-G301 PolarHBondContact O-N 3.4Å
302	P	42.6	Very low	50.7	Low	117 Å²	117	102.8 Å²	102.8	76%	0.76	65%	0.65	S	S	*	*			trans	-62.4	145.5	-163.4	24.8	-33.5	0	0	0	112	N304	P302-N304 PolarHBondContact O-N 3.1Å
303	A	43	Very low	50.9	Low	106 Å²	106	101.7 Å²	101.7	88%	0.876	64%	0.639	S	S	*	*			trans	-61.8	69.6	-179	0	0	0	0	0	112.9
304	N	35.9	Very low	51.7	Low	117 Å²	117	98.4 Å²	98.4	63%	0.626	62%	0.616	S	S	*	*			trans	-70.2	157	159.9	-96.2	-39.8	0	0	0	109	P302 S306 G307	P302-N304 PolarHBondContact O-N 3.1Å; N304-S306 PolarHBondContact O-N 3.3Å; N304-G307 PolarHBondContact O-N 2.89Å
305	I	50.9	Low	53.1	Low	149 Å²	149	95.6 Å²	95.6	76%	0.764	59%	0.586	S	S	*	*	H	α-helix	trans	-44.8	-31.2	177.1	-66.1	167.6	0	0	0	112	G307 R308 M309	I305-G307 VanDerWaalsContact C-N 3.34Å; I305-G307 PolarHBondContact O-N 2.88Å; I305-R308 PolarHBondContact O-N 3.08Å; I305-M309 PolarHBondContact O-N 3.38Å
306	S	46.1	Very low	54.8	Low	80 Å²	80	94.1 Å²	94.1	56%	0.559	58%	0.575	S	S	*	*	H	α-helix	trans	-54	-37.2	170.6	-51.9	0	0	0	0	115.1	N304 M309 Q310	N304-S306 PolarHBondContact O-N 3.3Å; S306-M309 PolarHBondContact O-N 2.94Å; S306-Q310 WeakPolarHBondContact O-CG 3.4Å; S306-Q310 PolarHBondContact O-N 2.75Å
307	G	49.1	Very low	57.1	Low	34 Å²	34	91.7 Å²	91.7	35%	0.351	56%	0.557	S	S	.	*	H	α-helix	trans	-68.3	-33.9	179.1	0	0	0	0	0	113.4	N304 I305 Q310 K311	N304-G307 PolarHBondContact O-N 2.89Å; I305-G307 VanDerWaalsContact C-N 3.34Å; I305-G307 PolarHBondContact O-N 2.88Å; G307-Q310 PolarHBondContact O-N 2.77Å; G307-K311 PolarHBondContact O-N 2.95Å
308	R	46.1	Very low	59.8	Low	210 Å²	210	85.8 Å²	85.8	79%	0.792	52%	0.517	S	S	*	.	H	α-helix	trans	-68.7	-40.6	173.4	-164.3	-173.9	-62.6	-174.9	1.6	110.8	I305 K311	I305-R308 PolarHBondContact O-N 3.08Å; R308-K311 WeakPolarHBondContact O-CB 3.49Å; R308-K311 PolarHBondContact O-N 2.99Å
309	M	45.8	Very low	62	Low	87 Å²	87	83.2 Å²	83.2	43%	0.429	48%	0.484	S	S	.	.	H	α-helix	trans	-70.2	-31.9	176.3	-61.8	-150	90.9	0	0	113	I305 S306 K311 V312 K361	I305-M309 PolarHBondContact O-N 3.38Å; S306-M309 PolarHBondContact O-N 2.94Å; M309-K311 VanDerWaalsContact C-N 3.27Å; M309-K311 PolarHBondContact O-N 3.39Å; M309-V312 PolarHBondContact O-N 2.85Å; M309-K361 WeakPolarHBondContact O-CE 3.5Å; M309-K361 PolarHBondContact O-NZ 3.02Å
310	Q	54.2	Low	64.6	Low	126 Å²	126	84.4 Å²	84.4	59%	0.589	48%	0.477	S	S	*	.	H	α-helix	trans	-63.9	-31.2	172	-80.1	-179.3	-58.8	0	0	112.6	S306 G307 V312	S306-Q310 WeakPolarHBondContact O-CG 3.4Å; S306-Q310 PolarHBondContact O-N 2.75Å; G307-Q310 PolarHBondContact O-N 2.77Å; Q310-V312 VanDerWaalsContact C-N 3.34Å
311	K	55.9	Low	67.2	Low	180 Å²	180	78.4 Å²	78.4	78%	0.783	44%	0.439	S	S	*	.	H	α-helix	trans	-70	-30.8	176.6	-159.7	175.7	-175.8	-175.8	0	112.7	G307 R308 M309 S313	G307-K311 PolarHBondContact O-N 2.95Å; R308-K311 WeakPolarHBondContact O-CB 3.49Å; R308-K311 PolarHBondContact O-N 2.99Å; M309-K311 VanDerWaalsContact C-N 3.27Å; M309-K311 PolarHBondContact O-N 3.39Å; K311-S313 PolarHBondContact O-N 3.41Å; K311-S313 VanDerWaalsContact O-N 3.12Å
312	V	65.8	Low	69.8	Low	67 Å²	67	75.6 Å²	75.6	41%	0.406	41%	0.41	S	S	.	.	S	Bend	trans	-70.6	110.8	173.3	-171.4	0	0	0	0	107.9	M309 Q310 M357 K361	M309-V312 PolarHBondContact O-N 2.85Å; Q310-V312 VanDerWaalsContact C-N 3.34Å; V312-M357 HydrophobicContact CB-CE 3.63Å; V312-M357 HydrophobicContact CG1-CE 3.55Å; V312-M357 VanDerWaalsContact O-CE 3.23Å; V312-M357 WeakPolarHBondContact O-CE 3.31Å; V312-K361 PolarHBondContact O-NZ 3.48Å
313	S	84	Confident	72.2	Confident	19 Å²	19	74 Å²	74	13%	0.133	39%	0.392	C	S	.	.			trans	-68.7	136.9	175.1	-55.9	0	0	0	0	108.8	D286 K311 F315 H316 C317	D286-S313 WeakPolarHBondContact OD2-CB 3.42Å; K311-S313 PolarHBondContact O-N 3.41Å; K311-S313 VanDerWaalsContact O-N 3.12Å; S313-F315 PolarHBondContact O-N 3Å; S313-H316 PolarHBondContact O-N 2.91Å; S313-H316 VanDerWaalsContact O-N 3.13Å; S313-C317 PolarHBondContact O-N 3.38Å
314	Y	90.6	Very high	74.7	Confident	1 Å²	1	71.6 Å²	71.6	0%	0.004	37%	0.366	C	S	.	.	H	α-helix	trans	-54.3	-37.3	177.4	-67.3	-80.6	0	0	0	110.7	V282 Y285 D286 H316 C317 T318 L354 M357 A358 K361 D363	V282-Y314 VanDerWaalsContact CG1-C 3.42Å; Y285-Y314 HydrophobicContact CD1-CD2 4.15Å; Y285-Y314 HydrophobicContact CD1-CE2 4.18Å; Y285-Y314 HydrophobicContact CE1-CD2 4.36Å; Y285-Y314 AromaticContact CE1-CE2 3.92Å; Y285-Y314 HydrophobicContact CE1-CE2 3.92Å; D286-Y314 WeakPolarHBondContact OD1-CD2 3.33Å; D286-Y314 PolarHBondContact OD1-N 3.01Å; D286-Y314 VanDerWaalsContact OD1-N 3.14Å; D286-Y314 PolarHBondContact OD2-N 3.45Å; Y314-H316 VanDerWaalsContact C-N 3.34Å; Y314-H316 PolarHBondContact O-N 3.1Å; Y314-C317 WeakPolarHBondContact O-CB 3.34Å; Y314-C317 PolarHBondContact O-N 2.85Å; Y314-T318 PolarHBondContact O-N 3.06Å; Y314-T318 PolarHBondContact O-OG1 2.91Å; Y314-T318 VanDerWaalsContact O-OG1 3.07Å; Y314-L354 HydrophobicContact CD1-CD1 4.2Å; Y314-M357 HydrophobicContact CD1-CB 4.13Å; Y314-M357 HydrophobicContact CD1-CG 3.77Å; Y314-M357 HydrophobicContact CD1-SD 3.34Å; Y314-M357 WeakPolarHBondContact CD1-SD 3.33Å; Y314-M357 HydrophobicContact CE1-CB 4.17Å; Y314-M357 HydrophobicContact CE1-CG 3.74Å; Y314-M357 HydrophobicContact CE1-SD 3.9Å; Y314-M357 HydrophobicContact CG-SD 4.04Å; Y314-A358 HydrophobicContact CE1-CB 4.36Å; Y314-K361 HydrophobicContact CE1-CD 3.69Å; Y314-K361 HydrophobicContact CE2-CD 4.11Å; Y314-K361 WeakPolarHBondContact OH-CB 3.26Å; Y314-K361 WeakPolarHBondContact OH-CD 3.38Å; Y314-D363 PolarHBondContact OH-OD2 3.3Å
315	F	93.4	Very high	77.5	Confident	5 Å²	5	66 Å²	66	2%	0.022	34%	0.336	C	S	.	.	H	α-helix	trans	-55.7	-45.4	178.7	179.8	-103.1	0	0	0	113.1	V29 L279 V282 L283 D286 S313 T318 L319	V29-F315 HydrophobicContact CG2-CE1 4.28Å; V29-F315 HydrophobicContact CG2-CZ 4.02Å; L279-F315 HydrophobicContact CB-CD2 4.31Å; L279-F315 HydrophobicContact CB-CE2 3.95Å; L279-F315 HydrophobicContact CD2-CE2 4.1Å; L279-F315 HydrophobicContact CG-CD2 4.46Å; L279-F315 HydrophobicContact CG-CE2 4.3Å; L279-F315 WeakPolarHBondContact O-CD2 3.26Å; V282-F315 HydrophobicContact CG1-CB 4.31Å; V282-F315 VanDerWaalsContact CG1-N 3.3Å; L283-F315 HydrophobicContact CB-CB 4.45Å; L283-F315 HydrophobicContact CB-CD2 3.58Å; L283-F315 HydrophobicContact CB-CE2 4Å; L283-F315 HydrophobicContact CB-CG 4.16Å; L283-F315 HydrophobicContact CD1-CB 3.76Å; L283-F315 HydrophobicContact CD1-CD1 3.73Å; L283-F315 HydrophobicContact CD1-CD2 3.71Å; L283-F315 HydrophobicContact CD1-CE1 4.2Å; L283-F315 HydrophobicContact CD1-CE2 4.16Å; L283-F315 HydrophobicContact CD1-CG 3.45Å; L283-F315 VanDerWaalsContact CD1-CG 3.45Å; L283-F315 HydrophobicContact CD1-CZ 4.39Å; L283-F315 HydrophobicContact CD2-CE2 4.28Å; L283-F315 HydrophobicContact CG-CD2 4.08Å; L283-F315 HydrophobicContact CG-CE2 4.34Å; L283-F315 HydrophobicContact CG-CG 4.3Å; D286-F315 WeakPolarHBondContact OD2-CB 3.46Å; D286-F315 PolarHBondContact OD2-N 2.9Å; S313-F315 PolarHBondContact O-N 3Å; F315-T318 WeakPolarHBondContact CA-OG1 2.9Å; F315-T318 PolarHBondContact O-N 3.35Å; F315-T318 PolarHBondContact O-OG1 3.46Å; F315-L319 HydrophobicContact CE1-CD2 4.13Å; F315-L319 WeakPolarHBondContact O-CB 3.5Å; F315-L319 PolarHBondContact O-N 3.46Å
316	H	92.5	Very high	79.4	Confident	107 Å²	107	59.1 Å²	59.1	50%	0.495	30%	0.301	S	S	.	.	H	α-helix	trans	-68.2	-40.4	-178.7	-71.7	74.9	0	0	0	110.8	S313 Y314 L319 I320	S313-H316 PolarHBondContact O-N 2.91Å; S313-H316 VanDerWaalsContact O-N 3.13Å; Y314-H316 VanDerWaalsContact C-N 3.34Å; Y314-H316 PolarHBondContact O-N 3.1Å; H316-L319 PolarHBondContact O-N 2.77Å; H316-I320 WeakPolarHBondContact O-CD1 3.28Å; H316-I320 WeakPolarHBondContact O-CG1 3.45Å; H316-I320 PolarHBondContact O-N 3.25Å
317	C	93.2	Very high	81.6	Confident	35 Å²	35	58.7 Å²	58.7	24%	0.236	29%	0.292	C	S	.	.	H	α-helix	trans	-60.9	-46.3	175.9	-177.8	0	0	0	0	111.2	S313 Y314 I320 G321 M357	S313-C317 PolarHBondContact O-N 3.38Å; Y314-C317 WeakPolarHBondContact O-CB 3.34Å; Y314-C317 PolarHBondContact O-N 2.85Å; C317-I320 PolarHBondContact O-N 3Å; C317-G321 PolarHBondContact O-N 2.97Å; C317-M357 HydrophobicContact CB-CE 4.38Å; C317-M357 HydrophobicContact CB-SD 3.77Å
318	T	94.6	Very high	83.6	Confident	0 Å²	0	59.2 Å²	59.2	0%	0	29%	0.288	C	S	.	.	H	α-helix	trans	-69	-32.5	177.3	50.5	0	0	0	0	113.6	V282 Y314 F315 G321 Y322 L354	V282-T318 HydrophobicContact CG1-CG2 4.5Å; V282-T318 HydrophobicContact CG2-CG2 4.35Å; Y314-T318 PolarHBondContact O-N 3.06Å; Y314-T318 PolarHBondContact O-OG1 2.91Å; Y314-T318 VanDerWaalsContact O-OG1 3.07Å; F315-T318 WeakPolarHBondContact CA-OG1 2.9Å; F315-T318 PolarHBondContact O-N 3.35Å; F315-T318 PolarHBondContact O-OG1 3.46Å; T318-G321 PolarHBondContact O-N 2.92Å; T318-Y322 PolarHBondContact O-N 3.39Å; T318-L354 HydrophobicContact CG2-CB 3.62Å; T318-L354 HydrophobicContact CG2-CD1 3.79Å; T318-L354 HydrophobicContact CG2-CD2 4.17Å; T318-L354 HydrophobicContact CG2-CG 4.06Å
319	L	95.3	Very high	85.7	Confident	29 Å²	29	49.7 Å²	49.7	15%	0.152	25%	0.254	C	S	.	.	H	α-helix	trans	-68.8	-40.8	176.2	-172.7	72.6	0	0	0	111.9	I25 V29 L279 F315 H316 G321 Y322 F323	I25-L319 HydrophobicContact CG2-CD1 4.25Å; I25-L319 HydrophobicContact CG2-CD2 4.45Å; V29-L319 HydrophobicContact CG2-CD1 4.23Å; V29-L319 HydrophobicContact CG2-CD2 4.09Å; L279-L319 HydrophobicContact CD2-CB 3.95Å; L279-L319 HydrophobicContact CD2-CD1 3.41Å; L279-L319 VanDerWaalsContact CD2-CD1 3.41Å; L279-L319 HydrophobicContact CD2-CG 4.31Å; F315-L319 HydrophobicContact CE1-CD2 4.13Å; F315-L319 WeakPolarHBondContact O-CB 3.5Å; F315-L319 PolarHBondContact O-N 3.46Å; H316-L319 PolarHBondContact O-N 2.77Å; L319-G321 VanDerWaalsContact C-N 3.32Å; L319-Y322 WeakPolarHBondContact O-CB 3.48Å; L319-Y322 PolarHBondContact O-N 2.9Å; L319-F323 PolarHBondContact O-N 3.38Å
320	I	94.7	Very high	87.6	Confident	111 Å²	111	46.9 Å²	46.9	57%	0.569	24%	0.242	S	C	*	.	H	α-helix	trans	-63.3	-43.1	171.6	-65.5	162.9	0	0	0	109.6	H316 C317 Y322 F323 V324	H316-I320 WeakPolarHBondContact O-CD1 3.28Å; H316-I320 WeakPolarHBondContact O-CG1 3.45Å; H316-I320 PolarHBondContact O-N 3.25Å; C317-I320 PolarHBondContact O-N 3Å; I320-Y322 VanDerWaalsContact C-N 3.34Å; I320-Y322 PolarHBondContact O-N 3.28Å; I320-F323 PolarHBondContact O-N 2.75Å; I320-V324 HydrophobicContact CG2-CG2 4.39Å; I320-V324 WeakPolarHBondContact O-CG2 3.38Å; I320-V324 PolarHBondContact O-N 3.18Å
321	G	95.6	Very high	89.3	Confident	7 Å²	7	43.9 Å²	43.9	7%	0.072	23%	0.232	C	C	.	.	H	α-helix	trans	-56.5	-44.9	173.3	0	0	0	0	0	112.9	C317 T318 L319 V324 G325 F349	C317-G321 PolarHBondContact O-N 2.97Å; T318-G321 PolarHBondContact O-N 2.92Å; L319-G321 VanDerWaalsContact C-N 3.32Å; G321-V324 PolarHBondContact O-N 2.89Å; G321-G325 PolarHBondContact O-N 3.42Å; G321-F349 CarbonylContact C-O 3.59Å; G321-F349 WeakPolarHBondContact CA-O 3.31Å; G321-F349 WeakPolarHBondContact O-CB 3.46Å
322	Y	95.7	Very high	90.9	Very high	0 Å²	0	35.8 Å²	35.8	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-58.8	-48	174.4	176.7	-100.5	0	0	0	112.1	I25 I28 D271 P275 T318 L319 I320 V324 G325 L326 L346 T350	I25-Y322 HydrophobicContact CG1-CD1 4.31Å; I25-Y322 HydrophobicContact CG1-CE1 4.35Å; I28-Y322 HydrophobicContact CD1-CD1 3.93Å; I28-Y322 HydrophobicContact CD1-CD2 4.29Å; I28-Y322 HydrophobicContact CD1-CE1 3.5Å; I28-Y322 HydrophobicContact CD1-CE2 3.9Å; I28-Y322 HydrophobicContact CD1-CG 4.31Å; I28-Y322 VanDerWaalsContact CD1-CZ 3.49Å; D271-Y322 PolarHBondContact O-OH 3.47Å; P275-Y322 HydrophobicContact CB-CD2 3.59Å; P275-Y322 HydrophobicContact CB-CE2 3.72Å; P275-Y322 HydrophobicContact CG-CD2 4.12Å; P275-Y322 HydrophobicContact CG-CE2 3.89Å; T318-Y322 PolarHBondContact O-N 3.39Å; L319-Y322 WeakPolarHBondContact O-CB 3.48Å; L319-Y322 PolarHBondContact O-N 2.9Å; I320-Y322 VanDerWaalsContact C-N 3.34Å; I320-Y322 PolarHBondContact O-N 3.28Å; Y322-V324 PolarHBondContact O-N 3.23Å; Y322-G325 PolarHBondContact O-N 2.93Å; Y322-L326 HydrophobicContact CE1-CD2 4.35Å; Y322-L326 WeakPolarHBondContact O-CB 3.44Å; Y322-L326 PolarHBondContact O-N 2.87Å; Y322-L346 HydrophobicContact CD2-CD2 3.66Å; Y322-L346 HydrophobicContact CE2-CD1 4.24Å; Y322-L346 HydrophobicContact CE2-CD2 3.69Å; Y322-L346 HydrophobicContact CG-CD2 4.47Å; Y322-T350 HydrophobicContact CD2-CG2 4.28Å
323	F	94.3	Very high	91.8	Very high	85 Å²	85	34.5 Å²	34.5	37%	0.373	19%	0.193	S	C	.	.	H	α-helix	trans	-60.3	-46.2	177.5	176.3	-102.7	0	0	0	112.3	F21 I25 L319 I320 G325 L326 L327	F21-F323 HydrophobicContact CD2-CE2 4.07Å; I25-F323 HydrophobicContact CD1-CB 4.26Å; I25-F323 HydrophobicContact CD1-CD2 3.8Å; I25-F323 HydrophobicContact CD1-CG 4.42Å; L319-F323 PolarHBondContact O-N 3.38Å; I320-F323 PolarHBondContact O-N 2.75Å; F323-G325 VanDerWaalsContact C-N 3.32Å; F323-G325 PolarHBondContact O-N 3.37Å; F323-L326 PolarHBondContact O-N 3.43Å; F323-L327 WeakPolarHBondContact O-CB 3.45Å; F323-L327 PolarHBondContact O-N 3.4Å
324	V	94.5	Very high	91.7	Very high	55 Å²	55	38.2 Å²	38.2	33%	0.333	20%	0.204	S	C	.	.	H	α-helix	trans	-63.8	-39	177.2	173.4	0	0	0	0	111.1	I320 G321 Y322 L327 T328 F349	I320-V324 HydrophobicContact CG2-CG2 4.39Å; I320-V324 WeakPolarHBondContact O-CG2 3.38Å; I320-V324 PolarHBondContact O-N 3.18Å; G321-V324 PolarHBondContact O-N 2.89Å; Y322-V324 PolarHBondContact O-N 3.23Å; V324-L327 PolarHBondContact O-N 3.21Å; V324-T328 WeakPolarHBondContact O-CB 2.95Å; V324-T328 PolarHBondContact O-N 2.67Å; V324-T328 PolarHBondContact O-OG1 3.31Å; V324-F349 HydrophobicContact CG1-CD1 3.95Å; V324-F349 HydrophobicContact CG1-CE1 3.92Å
325	G	94.5	Very high	91.5	Very high	0 Å²	0	44 Å²	44	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-63.7	-43.5	175.7	0	0	0	0	0	112.6	G321 Y322 F323 T328 A329	G321-G325 PolarHBondContact O-N 3.42Å; Y322-G325 PolarHBondContact O-N 2.93Å; F323-G325 VanDerWaalsContact C-N 3.32Å; F323-G325 PolarHBondContact O-N 3.37Å; G325-T328 PolarHBondContact O-N 3.37Å; G325-A329 WeakPolarHBondContact O-CB 3.33Å; G325-A329 PolarHBondContact O-N 3.3Å
326	L	91.8	Very high	91.1	Very high	4 Å²	4	49.5 Å²	49.5	2%	0.021	26%	0.259	C	S	.	.	H	α-helix	trans	-66.5	-43.6	177.4	-169.5	61.5	0	0	0	111.5	F21 L267 Y322 F323 T328 A329 T330 L346	F21-L326 HydrophobicContact CB-CD2 4.17Å; F21-L326 HydrophobicContact CD1-CD2 3.19Å; F21-L326 HydrophobicContact CD1-CG 3.6Å; F21-L326 HydrophobicContact CE1-CD1 4.24Å; F21-L326 HydrophobicContact CE1-CD2 3.66Å; F21-L326 HydrophobicContact CE1-CG 3.47Å; F21-L326 VanDerWaalsContact CE1-CG 3.47Å; F21-L326 HydrophobicContact CG-CD2 3.77Å; F21-L326 HydrophobicContact CG-CG 4.34Å; F21-L326 HydrophobicContact CZ-CG 4.12Å; L267-L326 HydrophobicContact CD1-CD1 4.13Å; Y322-L326 HydrophobicContact CE1-CD2 4.35Å; Y322-L326 WeakPolarHBondContact O-CB 3.44Å; Y322-L326 PolarHBondContact O-N 2.87Å; F323-L326 PolarHBondContact O-N 3.43Å; L326-T328 VanDerWaalsContact C-N 3.32Å; L326-T328 PolarHBondContact O-N 2.73Å; L326-A329 PolarHBondContact O-N 2.93Å; L326-T330 WeakPolarHBondContact O-CG2 3.48Å; L326-T330 PolarHBondContact O-N 2.95Å; L326-T330 PolarHBondContact O-OG1 3.41Å; L326-L346 HydrophobicContact CB-CD2 4.08Å
327	L	91.2	Very high	90.5	Very high	71 Å²	71	55.7 Å²	55.7	37%	0.372	28%	0.278	S	S	.	.	H	α-helix	trans	-57.9	-47	173.1	-176.7	66.8	0	0	0	110.8	F21 F323 V324 A329 T330 V331	F21-L327 HydrophobicContact CE2-CD1 4.16Å; F323-L327 WeakPolarHBondContact O-CB 3.45Å; F323-L327 PolarHBondContact O-N 3.4Å; V324-L327 PolarHBondContact O-N 3.21Å; L327-A329 PolarHBondContact O-N 3.05Å; L327-T330 PolarHBondContact O-N 2.68Å; L327-T330 PolarHBondContact O-OG1 2.86Å; L327-V331 WeakPolarHBondContact O-CG2 3.2Å; L327-V331 PolarHBondContact O-N 3.38Å
328	T	91.7	Very high	89.7	Confident	45 Å²	45	56.4 Å²	56.4	28%	0.276	29%	0.287	S	S	.	.	H	α-helix	trans	-62.7	-42.4	179.2	-53.7	0	0	0	0	111.6	V324 G325 L326 T330 V331 A332 Y345 F349	V324-T328 WeakPolarHBondContact O-CB 2.95Å; V324-T328 PolarHBondContact O-N 2.67Å; V324-T328 PolarHBondContact O-OG1 3.31Å; G325-T328 PolarHBondContact O-N 3.37Å; L326-T328 VanDerWaalsContact C-N 3.32Å; L326-T328 PolarHBondContact O-N 2.73Å; T328-T330 VanDerWaalsContact C-N 3.33Å; T328-T330 PolarHBondContact O-N 3Å; T328-V331 PolarHBondContact O-N 3Å; T328-A332 VanDerWaalsContact O-CB 3.23Å; T328-A332 WeakPolarHBondContact O-CB 3.44Å; T328-A332 PolarHBondContact O-N 2.91Å; T328-Y345 HydrophobicContact CG2-CD1 3.59Å; T328-Y345 HydrophobicContact CG2-CE1 4.02Å; T328-Y345 HydrophobicContact CG2-CG 4.48Å; T328-F349 HydrophobicContact CG2-CE2 3.95Å; T328-F349 HydrophobicContact CG2-CZ 4.4Å
329	A	90.3	Very high	88.6	Confident	9 Å²	9	60.4 Å²	60.4	7%	0.074	32%	0.32	C	S	.	.	H	α-helix	trans	-60.1	-42.8	176.4	0	0	0	0	0	111.9	G325 L326 L327 A332 S333 Y345	G325-A329 WeakPolarHBondContact O-CB 3.33Å; G325-A329 PolarHBondContact O-N 3.3Å; L326-A329 PolarHBondContact O-N 2.93Å; L327-A329 PolarHBondContact O-N 3.05Å; A329-A332 PolarHBondContact O-N 2.91Å; A329-S333 WeakPolarHBondContact O-CB 3.45Å; A329-S333 PolarHBondContact O-N 3.39Å; A329-Y345 HydrophobicContact CB-CD2 3.87Å; A329-Y345 HydrophobicContact CB-CG 4.11Å
330	T	86	Confident	87.9	Confident	28 Å²	28	60.9 Å²	60.9	17%	0.172	32%	0.321	C	S	.	.	H	α-helix	trans	-68.3	-43	178	59.3	0	0	0	0	113.1	F21 L326 L327 T328 A332 S333 R334	F21-T330 HydrophobicContact CE1-CG2 3.57Å; F21-T330 HydrophobicContact CZ-CG2 3.39Å; L326-T330 WeakPolarHBondContact O-CG2 3.48Å; L326-T330 PolarHBondContact O-N 2.95Å; L326-T330 PolarHBondContact O-OG1 3.41Å; L327-T330 PolarHBondContact O-N 2.68Å; L327-T330 PolarHBondContact O-OG1 2.86Å; T328-T330 VanDerWaalsContact C-N 3.33Å; T328-T330 PolarHBondContact O-N 3Å; T330-A332 VanDerWaalsContact C-N 3.32Å; T330-A332 PolarHBondContact O-N 3.23Å; T330-S333 PolarHBondContact O-N 2.93Å; T330-R334 WeakPolarHBondContact O-CG 3.06Å; T330-R334 PolarHBondContact O-N 3.35Å
331	V	88.9	Confident	87.4	Confident	64 Å²	64	55.8 Å²	55.8	39%	0.388	30%	0.296	S	S	.	.	H	α-helix	trans	-60.3	-45.9	175.8	170.5	0	0	0	0	110.1	L327 T328 R334 I335	L327-V331 WeakPolarHBondContact O-CG2 3.2Å; L327-V331 PolarHBondContact O-N 3.38Å; T328-V331 PolarHBondContact O-N 3Å; V331-R334 PolarHBondContact O-N 3.17Å; V331-I335 HydrophobicContact CG1-CD1 3.87Å; V331-I335 WeakPolarHBondContact O-CG1 3.3Å; V331-I335 PolarHBondContact O-N 3.48Å
332	A	89.5	Confident	86.9	Confident	10 Å²	10	56.1 Å²	56.1	8%	0.083	30%	0.297	C	S	.	.	H	α-helix	trans	-68.2	-37.4	-178.4	0	0	0	0	0	112.2	T328 A329 T330 R334 I335 H336 Q340 Y345	T328-A332 VanDerWaalsContact O-CB 3.23Å; T328-A332 WeakPolarHBondContact O-CB 3.44Å; T328-A332 PolarHBondContact O-N 2.91Å; A329-A332 PolarHBondContact O-N 2.91Å; T330-A332 VanDerWaalsContact C-N 3.32Å; T330-A332 PolarHBondContact O-N 3.23Å; A332-R334 PolarHBondContact O-N 2.75Å; A332-I335 PolarHBondContact O-N 3.43Å; A332-H336 PolarHBondContact O-N 3.33Å; A332-H336 PolarHBondContact O-ND1 3.41Å; A332-Q340 PolarHBondContact O-OE1 2.85Å; A332-Y345 HydrophobicContact CB-CE1 3.97Å; A332-Y345 HydrophobicContact CB-CE2 4.27Å; A332-Y345 WeakPolarHBondContact CB-OH 3.33Å
333	S	84.9	Confident	86.7	Confident	39 Å²	39	56.6 Å²	56.6	27%	0.273	30%	0.3	S	S	.	.	H	α-helix	trans	-64.4	-38.2	173.4	-178.9	0	0	0	0	112.4	A329 T330 R337 A338 Q340	A329-S333 WeakPolarHBondContact O-CB 3.45Å; A329-S333 PolarHBondContact O-N 3.39Å; T330-S333 PolarHBondContact O-N 2.93Å; S333-R337 WeakPolarHBondContact O-CA 3.25Å; S333-R337 PolarHBondContact O-N 2.99Å; S333-A338 PolarHBondContact OG-O 3.24Å; S333-Q340 VanDerWaalsContact N-OE1 3.08Å
334	R	82	Confident	86.6	Confident	98 Å²	98	55.4 Å²	55.4	37%	0.37	30%	0.297	S	S	.	.	H	α-helix	trans	-66.3	-39.6	175.2	-70.7	-156.6	-166.3	-139.6	16.7	112.6	S11 L12 Q17 T330 V331 A332	S11-R334 PolarHBondContact O-NH1 3.08Å; S11-R334 PolarHBondContact O-NH2 3.18Å; L12-R334 PolarHBondContact O-NH2 3.22Å; L12-R334 VanDerWaalsContact O-NH2 3.08Å; Q17-R334 VanDerWaalsContact CD-NH2 3.29Å; T330-R334 WeakPolarHBondContact O-CG 3.06Å; T330-R334 PolarHBondContact O-N 3.35Å; V331-R334 PolarHBondContact O-N 3.17Å; A332-R334 PolarHBondContact O-N 2.75Å
335	I	86.9	Confident	86.6	Confident	123 Å²	123	54.9 Å²	54.9	63%	0.631	29%	0.29	S	S	*	.	H	α-helix	trans	-64.6	-46.1	178.3	-69.2	166.9	0	0	0	110.7	V331 A332	V331-I335 HydrophobicContact CG1-CD1 3.87Å; V331-I335 WeakPolarHBondContact O-CG1 3.3Å; V331-I335 PolarHBondContact O-N 3.48Å; A332-I335 PolarHBondContact O-N 3.43Å
336	H	84.1	Confident	86.6	Confident	119 Å²	119	54.9 Å²	54.9	55%	0.551	29%	0.29	S	S	*	.	H	α-helix	trans	-84.8	-8.5	-175.7	-64.4	82.6	0	0	0	113.8	A332 A338 Q340	A332-H336 PolarHBondContact O-N 3.33Å; A332-H336 PolarHBondContact O-ND1 3.41Å; H336-A338 PolarHBondContact O-N 3.21Å; H336-Q340 PolarHBondContact ND1-NE2 3.46Å
337	R	80.8	Confident	86.7	Confident	237 Å²	237	55 Å²	55	89%	0.894	29%	0.29	S	S	*	.	T	Hydrogen-bonded Turn	trans	47.8	29.5	-173.2	-64.2	-162.7	172.7	140.4	-0.4	113.7	S333	S333-R337 WeakPolarHBondContact O-CA 3.25Å; S333-R337 PolarHBondContact O-N 2.99Å
338	A	76	Confident	86.9	Confident	51 Å²	51	53.9 Å²	53.9	42%	0.421	29%	0.287	S	S	.	.	S	Bend	trans	-130.7	147.7	178.2	0	0	0	0	0	108.3	S333 H336 Q340	S333-A338 PolarHBondContact OG-O 3.24Å; H336-A338 PolarHBondContact O-N 3.21Å; A338-Q340 PolarHBondContact O-N 2.95Å
339	A	72.4	Confident	87.1	Confident	84 Å²	84	55.2 Å²	55.2	69%	0.694	29%	0.289	S	S	*	.			trans	-62.6	123.8	168.9	0	0	0	0	0	108
340	Q	79.9	Confident	87.4	Confident	39 Å²	39	54.8 Å²	54.8	18%	0.182	29%	0.286	C	S	.	.			trans	-105.7	148.7	178.4	-73.8	-169.9	-33	0	0	110.5	A332 S333 H336 A338 A342 Y345	A332-Q340 PolarHBondContact O-OE1 2.85Å; S333-Q340 VanDerWaalsContact N-OE1 3.08Å; H336-Q340 PolarHBondContact ND1-NE2 3.46Å; A338-Q340 PolarHBondContact O-N 2.95Å; Q340-A342 PolarHBondContact O-N 2.9Å; Q340-A342 VanDerWaalsContact O-N 3.1Å; Q340-Y345 HydrophobicContact CB-CE2 4.25Å; Q340-Y345 PolarHBondContact NE2-OH 2.65Å; Q340-Y345 PolarHBondContact OE1-OH 2.97Å; Q340-Y345 VanDerWaalsContact OE1-OH 3.12Å
341	P	83.7	Confident	87.8	Confident	4 Å²	4	54.3 Å²	54.3	3%	0.026	28%	0.282	C	S	.	.			trans	-63.4	110.2	175.3	23.2	-28.8	0	0	0	109.4	D200 V204 F205 L343 L344	D200-P341 HydrophobicContact CB-CB 4.22Å; D200-P341 VanDerWaalsContact OD2-CA 3.26Å; D200-P341 WeakPolarHBondContact OD2-CA 3.21Å; D200-P341 WeakPolarHBondContact OD2-CB 3.23Å; V204-P341 HydrophobicContact CG2-CB 4.19Å; F205-P341 HydrophobicContact CE2-CG 3.96Å; F205-P341 HydrophobicContact CZ-CG 4.33Å; P341-L343 VanDerWaalsContact C-N 3.27Å; P341-L343 PolarHBondContact O-N 3.32Å; P341-L344 HydrophobicContact CB-CB 4.14Å; P341-L344 HydrophobicContact CG-CB 3.84Å; P341-L344 HydrophobicContact CG-CD2 3.93Å; P341-L344 VanDerWaalsContact O-CB 3.26Å; P341-L344 WeakPolarHBondContact O-CB 3.25Å; P341-L344 PolarHBondContact O-N 3.38Å
342	A	86.3	Confident	88.1	Confident	13 Å²	13	56.2 Å²	56.2	11%	0.107	29%	0.289	C	S	.	.	H	α-helix	trans	-66.3	-33.2	-175.8	0	0	0	0	0	111.6	D271 Q340 L344 Y345 L346	D271-A342 HydrophobicContact CB-CB 4.2Å; Q340-A342 PolarHBondContact O-N 2.9Å; Q340-A342 VanDerWaalsContact O-N 3.1Å; A342-L344 PolarHBondContact O-N 3.47Å; A342-Y345 PolarHBondContact O-N 2.93Å; A342-Y345 VanDerWaalsContact O-N 3.11Å; A342-L346 HydrophobicContact CB-CD1 4.08Å; A342-L346 VanDerWaalsContact O-CG 3.31Å; A342-L346 WeakPolarHBondContact O-CG 3.3Å; A342-L346 PolarHBondContact O-N 3.47Å
343	L	90.6	Very high	88.3	Confident	11 Å²	11	57.4 Å²	57.4	6%	0.058	30%	0.296	C	S	.	.	H	α-helix	trans	-62.8	-28	176.9	-67.5	179	0	0	0	112.7	L196 P275 P341 Y345 L346 V347	L196-L343 HydrophobicContact CB-CD1 3.99Å; P275-L343 HydrophobicContact CG-CD2 4.38Å; P341-L343 VanDerWaalsContact C-N 3.27Å; P341-L343 PolarHBondContact O-N 3.32Å; L343-Y345 PolarHBondContact O-N 3.11Å; L343-L346 PolarHBondContact O-N 2.87Å; L343-V347 HydrophobicContact CB-CG2 4.27Å; L343-V347 HydrophobicContact CD2-CG2 4.48Å; L343-V347 VanDerWaalsContact O-CB 3.31Å; L343-V347 WeakPolarHBondContact O-CB 3.27Å; L343-V347 VanDerWaalsContact O-CG2 3.22Å; L343-V347 WeakPolarHBondContact O-CG2 3.44Å; L343-V347 PolarHBondContact O-N 3.41Å
344	L	93.1	Very high	88.7	Confident	60 Å²	60	55.6 Å²	55.6	31%	0.314	28%	0.284	S	S	.	.	H	α-helix	trans	-56.6	-35.1	174.1	-177	63.1	0	0	0	112.7	L197 V201 P341 A342 P348	L197-L344 VanDerWaalsContact CD1-CA 3.44Å; L197-L344 HydrophobicContact CD1-CB 4.15Å; L197-L344 HydrophobicContact CD1-CD1 3.79Å; V201-L344 HydrophobicContact CG2-CD1 3.94Å; P341-L344 HydrophobicContact CB-CB 4.14Å; P341-L344 HydrophobicContact CG-CB 3.84Å; P341-L344 HydrophobicContact CG-CD2 3.93Å; P341-L344 VanDerWaalsContact O-CB 3.26Å; P341-L344 WeakPolarHBondContact O-CB 3.25Å; P341-L344 PolarHBondContact O-N 3.38Å; A342-L344 PolarHBondContact O-N 3.47Å; L344-P348 WeakPolarHBondContact O-CD 3.48Å; L344-P348 VanDerWaalsContact O-CG 3.23Å; L344-P348 WeakPolarHBondContact O-CG 3.48Å
345	Y	94	Very high	89.3	Confident	44 Å²	44	53 Å²	53	17%	0.173	28%	0.277	C	S	.	.	H	α-helix	trans	-92.3	-45.7	177.1	-59.9	-85.7	0	0	0	110.6	T328 A329 A332 Q340 A342 L343 V347 P348 F349	T328-Y345 HydrophobicContact CG2-CD1 3.59Å; T328-Y345 HydrophobicContact CG2-CE1 4.02Å; T328-Y345 HydrophobicContact CG2-CG 4.48Å; A329-Y345 HydrophobicContact CB-CD2 3.87Å; A329-Y345 HydrophobicContact CB-CG 4.11Å; A332-Y345 HydrophobicContact CB-CE1 3.97Å; A332-Y345 HydrophobicContact CB-CE2 4.27Å; A332-Y345 WeakPolarHBondContact CB-OH 3.33Å; Q340-Y345 HydrophobicContact CB-CE2 4.25Å; Q340-Y345 PolarHBondContact NE2-OH 2.65Å; Q340-Y345 PolarHBondContact OE1-OH 2.97Å; Q340-Y345 VanDerWaalsContact OE1-OH 3.12Å; A342-Y345 PolarHBondContact O-N 2.93Å; A342-Y345 VanDerWaalsContact O-N 3.11Å; L343-Y345 PolarHBondContact O-N 3.11Å; Y345-V347 PolarHBondContact O-N 3.22Å; Y345-P348 VanDerWaalsContact O-CD 3.26Å; Y345-P348 WeakPolarHBondContact O-CD 3.41Å; Y345-P348 VanDerWaalsContact O-CG 3.32Å; Y345-P348 WeakPolarHBondContact O-CG 3.3Å; Y345-F349 WeakPolarHBondContact O-CB 3.18Å; Y345-F349 WeakPolarHBondContact O-CD2 3.31Å; Y345-F349 PolarHBondContact O-N 3.21Å
346	L	93.9	Very high	89.6	Confident	0 Å²	0	51 Å²	51	0%	0	27%	0.27	C	S	.	.	H	α-helix	trans	-62.7	-40.6	-174.4	-69	167.9	0	0	0	113.4	D271 P275 Y322 L326 A342 L343 F349 T350	D271-L346 HydrophobicContact CB-CD1 4Å; P275-L346 HydrophobicContact CG-CB 4.28Å; P275-L346 HydrophobicContact CG-CD1 4.29Å; Y322-L346 HydrophobicContact CD2-CD2 3.66Å; Y322-L346 HydrophobicContact CE2-CD1 4.24Å; Y322-L346 HydrophobicContact CE2-CD2 3.69Å; Y322-L346 HydrophobicContact CG-CD2 4.47Å; L326-L346 HydrophobicContact CB-CD2 4.08Å; A342-L346 HydrophobicContact CB-CD1 4.08Å; A342-L346 VanDerWaalsContact O-CG 3.31Å; A342-L346 WeakPolarHBondContact O-CG 3.3Å; A342-L346 PolarHBondContact O-N 3.47Å; L343-L346 PolarHBondContact O-N 2.87Å; L346-F349 PolarHBondContact O-N 3.2Å; L346-T350 WeakPolarHBondContact O-CB 3.22Å; L346-T350 VanDerWaalsContact O-CG2 3.31Å; L346-T350 WeakPolarHBondContact O-CG2 3.3Å; L346-T350 PolarHBondContact O-N 2.88Å; L346-T350 PolarHBondContact O-OG1 3.16Å
347	V	95.1	Very high	89.9	Confident	6 Å²	6	46 Å²	46	4%	0.036	25%	0.247	C	C	.	.	H	α-helix	trans	-62.1	-54.9	-177	173.9	0	0	0	0	112.4	L193 L197 L343 Y345 F349 T350 L351	L193-V347 HydrophobicContact CB-CG1 4.08Å; L193-V347 HydrophobicContact CB-CG2 4.04Å; L193-V347 HydrophobicContact CD2-CG2 4.3Å; L197-V347 HydrophobicContact CB-CG2 4.37Å; L197-V347 HydrophobicContact CD2-CG1 4.26Å; L343-V347 HydrophobicContact CB-CG2 4.27Å; L343-V347 HydrophobicContact CD2-CG2 4.48Å; L343-V347 VanDerWaalsContact O-CB 3.31Å; L343-V347 WeakPolarHBondContact O-CB 3.27Å; L343-V347 VanDerWaalsContact O-CG2 3.22Å; L343-V347 WeakPolarHBondContact O-CG2 3.44Å; L343-V347 PolarHBondContact O-N 3.41Å; Y345-V347 PolarHBondContact O-N 3.22Å; V347-F349 PolarHBondContact O-N 3.39Å; V347-T350 PolarHBondContact O-N 2.95Å; V347-T350 PolarHBondContact O-OG1 3.46Å; V347-L351 HydrophobicContact CG1-CD1 3.68Å; V347-L351 HydrophobicContact CG1-CG 4.36Å; V347-L351 VanDerWaalsContact O-CB 3.31Å; V347-L351 WeakPolarHBondContact O-CB 3.42Å; V347-L351 PolarHBondContact O-N 3.4Å
348	P	95	Very high	90.4	Very high	47 Å²	47	34.7 Å²	34.7	31%	0.305	21%	0.205	S	C	.	.	H	α-helix	trans	-63.4	-39.9	177.2	23.1	-32.5	0	0	0	112.2	L344 Y345 T350 L352	L344-P348 WeakPolarHBondContact O-CD 3.48Å; L344-P348 VanDerWaalsContact O-CG 3.23Å; L344-P348 WeakPolarHBondContact O-CG 3.48Å; Y345-P348 VanDerWaalsContact O-CD 3.26Å; Y345-P348 WeakPolarHBondContact O-CD 3.41Å; Y345-P348 VanDerWaalsContact O-CG 3.32Å; Y345-P348 WeakPolarHBondContact O-CG 3.3Å; P348-T350 VanDerWaalsContact C-N 3.28Å; P348-T350 PolarHBondContact O-N 3.34Å; P348-L352 HydrophobicContact CB-CD1 3.98Å; P348-L352 HydrophobicContact CB-CG 4.49Å; P348-L352 WeakPolarHBondContact O-CB 3.26Å; P348-L352 VanDerWaalsContact O-CG 3.25Å; P348-L352 WeakPolarHBondContact O-CG 3.32Å; P348-L352 PolarHBondContact O-N 2.98Å
349	F	95.7	Very high	91.1	Very high	74 Å²	74	40.4 Å²	40.4	33%	0.325	22%	0.217	S	C	.	.	H	α-helix	trans	-71.4	-18	-179.3	-78.2	-68.2	0	0	0	114.2	G321 V324 T328 Y345 L346 V347 P353	G321-F349 CarbonylContact C-O 3.59Å; G321-F349 WeakPolarHBondContact CA-O 3.31Å; G321-F349 WeakPolarHBondContact O-CB 3.46Å; V324-F349 HydrophobicContact CG1-CD1 3.95Å; V324-F349 HydrophobicContact CG1-CE1 3.92Å; T328-F349 HydrophobicContact CG2-CE2 3.95Å; T328-F349 HydrophobicContact CG2-CZ 4.4Å; Y345-F349 WeakPolarHBondContact O-CB 3.18Å; Y345-F349 WeakPolarHBondContact O-CD2 3.31Å; Y345-F349 PolarHBondContact O-N 3.21Å; L346-F349 PolarHBondContact O-N 3.2Å; V347-F349 PolarHBondContact O-N 3.39Å; F349-P353 WeakPolarHBondContact O-CD 3.45Å; F349-P353 WeakPolarHBondContact O-CG 3.34Å
350	T	95.6	Very high	92	Very high	0 Å²	0	42.3 Å²	42.3	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-97.7	-42.5	174.3	53.3	0	0	0	0	112.5	Y322 L346 V347 P348 L354	Y322-T350 HydrophobicContact CD2-CG2 4.28Å; L346-T350 WeakPolarHBondContact O-CB 3.22Å; L346-T350 VanDerWaalsContact O-CG2 3.31Å; L346-T350 WeakPolarHBondContact O-CG2 3.3Å; L346-T350 PolarHBondContact O-N 2.88Å; L346-T350 PolarHBondContact O-OG1 3.16Å; V347-T350 PolarHBondContact O-N 2.95Å; V347-T350 PolarHBondContact O-OG1 3.46Å; P348-T350 VanDerWaalsContact C-N 3.28Å; P348-T350 PolarHBondContact O-N 3.34Å; T350-L354 WeakPolarHBondContact O-CB 3.28Å; T350-L354 PolarHBondContact O-N 3.36Å
351	L	95.3	Very high	92.3	Very high	17 Å²	17	42.5 Å²	42.5	9%	0.089	22%	0.215	C	C	.	.	H	α-helix	trans	-75.2	-41.6	-179	-72.1	-178.7	0	0	0	113.1	L193 L278 V347 L354 L355	L193-L351 HydrophobicContact CB-CD1 4.18Å; L193-L351 HydrophobicContact CD1-CD1 4.24Å; L193-L351 HydrophobicContact CD1-CD2 3.94Å; L193-L351 HydrophobicContact CD1-CG 4Å; L278-L351 HydrophobicContact CD1-CD2 4.05Å; L278-L351 HydrophobicContact CD2-CD2 3.8Å; L278-L351 HydrophobicContact CD2-CG 4.47Å; V347-L351 HydrophobicContact CG1-CD1 3.68Å; V347-L351 HydrophobicContact CG1-CG 4.36Å; V347-L351 VanDerWaalsContact O-CB 3.31Å; V347-L351 WeakPolarHBondContact O-CB 3.42Å; V347-L351 PolarHBondContact O-N 3.4Å; L351-L354 PolarHBondContact O-N 3.27Å; L351-L355 HydrophobicContact CB-CD1 4.38Å; L351-L355 WeakPolarHBondContact O-CB 3.44Å; L351-L355 VanDerWaalsContact O-CG 3.22Å; L351-L355 WeakPolarHBondContact O-CG 3.34Å; L351-L355 PolarHBondContact O-N 2.87Å
352	L	94.6	Very high	92.3	Very high	104 Å²	104	45.3 Å²	45.3	55%	0.545	24%	0.244	S	C	.	.	H	α-helix	trans	-64.9	-47.9	-176.7	-65.6	171.1	0	0	0	112.2	P348 L354 L355 T356	P348-L352 HydrophobicContact CB-CD1 3.98Å; P348-L352 HydrophobicContact CB-CG 4.49Å; P348-L352 WeakPolarHBondContact O-CB 3.26Å; P348-L352 VanDerWaalsContact O-CG 3.25Å; P348-L352 WeakPolarHBondContact O-CG 3.32Å; P348-L352 PolarHBondContact O-N 2.98Å; L352-L354 VanDerWaalsContact C-N 3.27Å; L352-L354 PolarHBondContact O-N 2.69Å; L352-L355 PolarHBondContact O-N 3.06Å; L352-T356 WeakPolarHBondContact O-CB 3.42Å; L352-T356 WeakPolarHBondContact O-CG2 3.29Å; L352-T356 PolarHBondContact O-N 3.01Å; L352-T356 PolarHBondContact O-OG1 3.4Å
353	P	93.5	Very high	92.3	Very high	35 Å²	35	46 Å²	46	23%	0.227	25%	0.246	C	C	.	.	H	α-helix	trans	-61.3	-37	175.2	-26	38.6	0	0	0	112.5	F349 T356 M357	F349-P353 WeakPolarHBondContact O-CD 3.45Å; F349-P353 WeakPolarHBondContact O-CG 3.34Å; P353-T356 VanDerWaalsContact CA-OG1 3.31Å; P353-T356 WeakPolarHBondContact CA-OG1 3.19Å; P353-T356 PolarHBondContact O-OG1 3.47Å; P353-M357 WeakPolarHBondContact O-CB 3.26Å; P353-M357 PolarHBondContact O-N 3.29Å
354	L	94.3	Very high	92.2	Very high	1 Å²	1	47.8 Å²	47.8	1%	0.005	26%	0.255	C	S	.	.	H	α-helix	trans	-64.6	-51.5	176.6	-177.1	54.4	0	0	0	112.1	L186 L278 V282 Y314 T318 T350 L351 L352 M357 A358 M367	L186-L354 HydrophobicContact CD1-CD2 3.37Å; L186-L354 HydrophobicContact CD1-CG 3.99Å; L278-L354 HydrophobicContact CD1-CD2 3.73Å; L278-L354 HydrophobicContact CD2-CD2 4.25Å; L278-L354 HydrophobicContact CG-CD2 4.19Å; V282-L354 HydrophobicContact CG1-CD1 4.23Å; V282-L354 HydrophobicContact CG2-CD1 3.76Å; V282-L354 HydrophobicContact CG2-CD2 3.52Å; V282-L354 HydrophobicContact CG2-CG 4.3Å; Y314-L354 HydrophobicContact CD1-CD1 4.2Å; T318-L354 HydrophobicContact CG2-CB 3.62Å; T318-L354 HydrophobicContact CG2-CD1 3.79Å; T318-L354 HydrophobicContact CG2-CD2 4.17Å; T318-L354 HydrophobicContact CG2-CG 4.06Å; T350-L354 WeakPolarHBondContact O-CB 3.28Å; T350-L354 PolarHBondContact O-N 3.36Å; L351-L354 PolarHBondContact O-N 3.27Å; L352-L354 VanDerWaalsContact C-N 3.27Å; L352-L354 PolarHBondContact O-N 2.69Å; L354-M357 PolarHBondContact O-N 2.94Å; L354-A358 WeakPolarHBondContact O-CB 3.38Å; L354-A358 PolarHBondContact O-N 2.97Å; L354-M367 HydrophobicContact CD1-CE 3.84Å; L354-M367 HydrophobicContact CD1-SD 4.17Å; L354-M367 HydrophobicContact CD2-CE 4.41Å; L354-M367 HydrophobicContact CG-CE 4.5Å
355	L	94.6	Very high	92	Very high	45 Å²	45	55.2 Å²	55.2	24%	0.236	28%	0.279	C	S	.	.	H	α-helix	trans	-64.6	-42.8	-178.5	-71.4	169.1	0	0	0	111.2	L186 L351 L352 A358 Y359 L364 W368	L186-L355 HydrophobicContact CD2-CD2 3.73Å; L186-L355 HydrophobicContact CG-CD2 4.49Å; L351-L355 HydrophobicContact CB-CD1 4.38Å; L351-L355 WeakPolarHBondContact O-CB 3.44Å; L351-L355 VanDerWaalsContact O-CG 3.22Å; L351-L355 WeakPolarHBondContact O-CG 3.34Å; L351-L355 PolarHBondContact O-N 2.87Å; L352-L355 PolarHBondContact O-N 3.06Å; L355-A358 PolarHBondContact O-N 3.06Å; L355-Y359 WeakPolarHBondContact O-CB 3.47Å; L355-Y359 PolarHBondContact O-N 3.23Å; L355-L364 HydrophobicContact CD2-CD1 3.72Å; L355-W368 HydrophobicContact CD2-CZ3 4.32Å
356	T	92.4	Very high	91.6	Very high	79 Å²	79	57.5 Å²	57.5	49%	0.485	29%	0.287	S	S	.	.	H	α-helix	trans	-63.5	-46.3	176.1	52.7	0	0	0	0	111.1	L352 P353 A358 Y359 L360	L352-T356 WeakPolarHBondContact O-CB 3.42Å; L352-T356 WeakPolarHBondContact O-CG2 3.29Å; L352-T356 PolarHBondContact O-N 3.01Å; L352-T356 PolarHBondContact O-OG1 3.4Å; P353-T356 VanDerWaalsContact CA-OG1 3.31Å; P353-T356 WeakPolarHBondContact CA-OG1 3.19Å; P353-T356 PolarHBondContact O-OG1 3.47Å; T356-A358 PolarHBondContact O-N 2.93Å; T356-Y359 PolarHBondContact O-N 3.4Å; T356-L360 WeakPolarHBondContact O-CB 3.41Å; T356-L360 WeakPolarHBondContact O-CG 3.33Å; T356-L360 PolarHBondContact O-N 3.11Å
357	M	90.8	Very high	91.3	Very high	15 Å²	15	57.5 Å²	57.5	7%	0.074	29%	0.287	C	S	.	.	H	α-helix	trans	-64.7	-39.2	176.8	-166.2	-172.6	-156.7	0	0	112.3	V312 Y314 C317 P353 L354 K361	V312-M357 HydrophobicContact CB-CE 3.63Å; V312-M357 HydrophobicContact CG1-CE 3.55Å; V312-M357 VanDerWaalsContact O-CE 3.23Å; V312-M357 WeakPolarHBondContact O-CE 3.31Å; Y314-M357 HydrophobicContact CD1-CB 4.13Å; Y314-M357 HydrophobicContact CD1-CG 3.77Å; Y314-M357 HydrophobicContact CD1-SD 3.34Å; Y314-M357 WeakPolarHBondContact CD1-SD 3.33Å; Y314-M357 HydrophobicContact CE1-CB 4.17Å; Y314-M357 HydrophobicContact CE1-CG 3.74Å; Y314-M357 HydrophobicContact CE1-SD 3.9Å; Y314-M357 HydrophobicContact CG-SD 4.04Å; C317-M357 HydrophobicContact CB-CE 4.38Å; C317-M357 HydrophobicContact CB-SD 3.77Å; P353-M357 WeakPolarHBondContact O-CB 3.26Å; P353-M357 PolarHBondContact O-N 3.29Å; L354-M357 PolarHBondContact O-N 2.94Å; M357-K361 HydrophobicContact CG-CD 4.34Å; M357-K361 WeakPolarHBondContact O-CB 3.45Å; M357-K361 WeakPolarHBondContact O-CG 3.28Å; M357-K361 PolarHBondContact O-N 3.41Å
358	A	91	Very high	91.1	Very high	0 Å²	0	62.2 Å²	62.2	0%	0	31%	0.305	C	S	.	.	H	α-helix	trans	-67.5	-37.9	176.8	0	0	0	0	0	111.9	Y314 L354 L355 T356 G362 D363 L364 M367	Y314-A358 HydrophobicContact CE1-CB 4.36Å; L354-A358 WeakPolarHBondContact O-CB 3.38Å; L354-A358 PolarHBondContact O-N 2.97Å; L355-A358 PolarHBondContact O-N 3.06Å; T356-A358 PolarHBondContact O-N 2.93Å; A358-G362 PolarHBondContact O-N 2.94Å; A358-D363 PolarHBondContact O-N 2.79Å; A358-L364 HydrophobicContact CB-CB 4.21Å; A358-L364 HydrophobicContact CB-CD1 3.93Å; A358-L364 PolarHBondContact O-N 3.33Å; A358-L364 VanDerWaalsContact O-N 3.12Å; A358-M367 HydrophobicContact CB-SD 4.31Å
359	Y	91.5	Very high	90.5	Very high	171 Å²	171	63.3 Å²	63.3	67%	0.671	31%	0.313	S	S	*	.	H	α-helix	trans	-66.4	-49.4	174.2	-178.5	-101.2	0	0	0	111.4	L355 T356 K361 G362 L364	L355-Y359 WeakPolarHBondContact O-CB 3.47Å; L355-Y359 PolarHBondContact O-N 3.23Å; T356-Y359 PolarHBondContact O-N 3.4Å; Y359-K361 VanDerWaalsContact C-N 3.28Å; Y359-K361 PolarHBondContact O-N 2.88Å; Y359-G362 PolarHBondContact O-N 3.48Å; Y359-L364 HydrophobicContact CD2-CD2 4.12Å
360	L	90.2	Very high	89.6	Confident	123 Å²	123	64.8 Å²	64.8	64%	0.644	32%	0.321	S	S	*	.	H	α-helix	trans	-61.6	-34.1	179.3	-71	173	0	0	0	112.9	T356 G362	T356-L360 WeakPolarHBondContact O-CB 3.41Å; T356-L360 WeakPolarHBondContact O-CG 3.33Å; T356-L360 PolarHBondContact O-N 3.11Å; L360-G362 VanDerWaalsContact C-N 3.33Å
361	K	86.7	Confident	88.7	Confident	44 Å²	44	65 Å²	65	19%	0.191	32%	0.322	C	S	.	.	T	Hydrogen-bonded Turn	trans	-82.5	-7.3	175.2	-74.8	177.2	171.8	178.9	0	113.6	M309 V312 Y314 M357 Y359 D363	M309-K361 WeakPolarHBondContact O-CE 3.5Å; M309-K361 PolarHBondContact O-NZ 3.02Å; V312-K361 PolarHBondContact O-NZ 3.48Å; Y314-K361 HydrophobicContact CE1-CD 3.69Å; Y314-K361 HydrophobicContact CE2-CD 4.11Å; Y314-K361 WeakPolarHBondContact OH-CB 3.26Å; Y314-K361 WeakPolarHBondContact OH-CD 3.38Å; M357-K361 HydrophobicContact CG-CD 4.34Å; M357-K361 WeakPolarHBondContact O-CB 3.45Å; M357-K361 WeakPolarHBondContact O-CG 3.28Å; M357-K361 PolarHBondContact O-N 3.41Å; Y359-K361 VanDerWaalsContact C-N 3.28Å; Y359-K361 PolarHBondContact O-N 2.88Å; K361-D363 PolarHBondContact O-N 3.27Å
362	G	84.4	Confident	87.8	Confident	62 Å²	62	67.6 Å²	67.6	64%	0.639	33%	0.333	S	S	*	.	T	Hydrogen-bonded Turn	trans	73.3	5	-177.7	0	0	0	0	0	115.1	A358 Y359 L360	A358-G362 PolarHBondContact O-N 2.94Å; Y359-G362 PolarHBondContact O-N 3.48Å; L360-G362 VanDerWaalsContact C-N 3.33Å
363	D	86.7	Confident	86.3	Confident	29 Å²	29	67.9 Å²	67.9	16%	0.155	33%	0.332	C	S	.	.			trans	-89	-3.5	-176.6	-73.1	-40.5	0	0	0	113.1	K289 Y314 A358 K361 R365 R366 M367	K289-D363 IonicContact NZ-OD2 2.6Å; K289-D363 PolarHBondContact NZ-OD2 2.9Å; Y314-D363 PolarHBondContact OH-OD2 3.3Å; A358-D363 PolarHBondContact O-N 2.79Å; K361-D363 PolarHBondContact O-N 3.27Å; D363-R365 VanDerWaalsContact C-N 3.35Å; D363-R365 PolarHBondContact O-N 2.79Å; D363-R366 WeakPolarHBondContact O-CB 3.3Å; D363-R366 PolarHBondContact O-N 3.44Å; D363-R366 VanDerWaalsContact O-N 3.1Å; D363-M367 PolarHBondContact O-N 3.12Å
364	L	88.2	Confident	84.2	Confident	47 Å²	47	70.2 Å²	70.2	25%	0.246	35%	0.349	C	S	.	.	H	α-helix	trans	-53.4	-47.6	-174.3	-177.9	65	0	0	0	112.8	L186 L355 A358 Y359 R366 M367 W368	L186-L364 HydrophobicContact CD2-CD1 3.81Å; L355-L364 HydrophobicContact CD2-CD1 3.72Å; A358-L364 HydrophobicContact CB-CB 4.21Å; A358-L364 HydrophobicContact CB-CD1 3.93Å; A358-L364 PolarHBondContact O-N 3.33Å; A358-L364 VanDerWaalsContact O-N 3.12Å; Y359-L364 HydrophobicContact CD2-CD2 4.12Å; L364-R366 VanDerWaalsContact C-N 3.31Å; L364-R366 PolarHBondContact O-N 3.03Å; L364-M367 PolarHBondContact O-N 3.33Å; L364-W368 WeakPolarHBondContact O-CB 3.32Å; L364-W368 PolarHBondContact O-N 3.17Å
365	R	87.9	Confident	81.7	Confident	217 Å²	217	79.6 Å²	79.6	82%	0.819	39%	0.39	S	S	*	.	H	α-helix	trans	-60.7	-42.7	-179.3	-175.7	177	177.5	-175.5	-0.6	111.5	D363 W368 S369	D363-R365 VanDerWaalsContact C-N 3.35Å; D363-R365 PolarHBondContact O-N 2.79Å; R365-W368 PolarHBondContact O-N 3.29Å; R365-S369 PolarHBondContact O-N 2.88Å; R365-S369 PolarHBondContact O-OG 3.42Å
366	R	86.9	Confident	78.8	Confident	91 Å²	91	82.3 Å²	82.3	34%	0.343	41%	0.412	S	S	.	.	H	α-helix	trans	-65.4	-47	177.8	-175.3	178.6	-177.1	-174.5	7.1	111	D363 L364 W368 E370 P371	D363-R366 WeakPolarHBondContact O-CB 3.3Å; D363-R366 PolarHBondContact O-N 3.44Å; D363-R366 VanDerWaalsContact O-N 3.1Å; L364-R366 VanDerWaalsContact C-N 3.31Å; L364-R366 PolarHBondContact O-N 3.03Å; R366-W368 VanDerWaalsContact C-N 3.25Å; R366-W368 PolarHBondContact O-N 3.14Å; R366-E370 CarbonylContact O-C 3.6Å; R366-E370 PolarHBondContact O-N 3.18Å; R366-E370 VanDerWaalsContact O-N 3.14Å; R366-P371 WeakPolarHBondContact O-CA 3.46Å; R366-P371 VanDerWaalsContact O-N 3.15Å
367	M	87.7	Confident	76.1	Confident	0 Å²	0	83.7 Å²	83.7	0%	0	43%	0.425	C	S	.	.	H	α-helix	trans	-64.8	-31.4	179.1	-154.8	-177	-173.3	0	0	112.4	L186 F281 V282 Y285 L354 A358 D363 L364	L186-M367 HydrophobicContact CB-CB 4.42Å; L186-M367 HydrophobicContact CB-CG 4.02Å; L186-M367 WeakPolarHBondContact CB-O 3.17Å; L186-M367 HydrophobicContact CD1-CE 4.19Å; L186-M367 HydrophobicContact CD1-SD 4.09Å; L186-M367 HydrophobicContact CD2-CB 4.26Å; L186-M367 HydrophobicContact CD2-CG 4.21Å; L186-M367 HydrophobicContact CD2-SD 4.05Å; L186-M367 PolarHBondContact N-O 3.31Å; F281-M367 HydrophobicContact CD1-CE 4.08Å; F281-M367 HydrophobicContact CE1-CE 3.46Å; F281-M367 VanDerWaalsContact CE1-CE 3.46Å; F281-M367 HydrophobicContact CE1-CG 4.01Å; F281-M367 HydrophobicContact CE1-SD 4.46Å; F281-M367 HydrophobicContact CZ-CE 4.24Å; F281-M367 HydrophobicContact CZ-CG 4.05Å; V282-M367 HydrophobicContact CB-CE 4.49Å; V282-M367 HydrophobicContact CG2-CE 3.87Å; Y285-M367 HydrophobicContact CD1-CE 4.01Å; Y285-M367 HydrophobicContact CD1-CG 4.34Å; Y285-M367 HydrophobicContact CD1-SD 4.31Å; Y285-M367 HydrophobicContact CD2-CG 4.32Å; Y285-M367 HydrophobicContact CE1-CG 4.32Å; Y285-M367 HydrophobicContact CE1-SD 4.43Å; Y285-M367 HydrophobicContact CE2-CB 4.46Å; Y285-M367 HydrophobicContact CE2-CG 4.29Å; Y285-M367 HydrophobicContact CG-CE 4.15Å; Y285-M367 HydrophobicContact CG-CG 4.33Å; L354-M367 HydrophobicContact CD1-CE 3.84Å; L354-M367 HydrophobicContact CD1-SD 4.17Å; L354-M367 HydrophobicContact CD2-CE 4.41Å; L354-M367 HydrophobicContact CG-CE 4.5Å; A358-M367 HydrophobicContact CB-SD 4.31Å; D363-M367 PolarHBondContact O-N 3.12Å; L364-M367 PolarHBondContact O-N 3.33Å
368	W	90.5	Very high	73.4	Confident	106 Å²	106	88.1 Å²	88.1	40%	0.402	46%	0.457	S	S	.	.	H	α-helix	trans	-72	-50.4	-177.3	-170.4	-91.1	0	0	0	114.3	S185 L186 K187 C190 L355 L364 R365 R366	S185-W368 WeakPolarHBondContact CB-O 3.19Å; L186-W368 HydrophobicContact CD2-CE3 4.08Å; L186-W368 HydrophobicContact CG-CE3 4.38Å; K187-W368 HydrophobicContact CB-CD2 4.09Å; K187-W368 HydrophobicContact CB-CG 4.33Å; K187-W368 HydrophobicContact CB-CZ2 4.17Å; K187-W368 WeakPolarHBondContact CB-O 3.47Å; K187-W368 HydrophobicContact CG-CZ2 3.99Å; C190-W368 HydrophobicContact CB-CH2 4.45Å; C190-W368 HydrophobicContact CB-CZ3 4.47Å; L355-W368 HydrophobicContact CD2-CZ3 4.32Å; L364-W368 WeakPolarHBondContact O-CB 3.32Å; L364-W368 PolarHBondContact O-N 3.17Å; R365-W368 PolarHBondContact O-N 3.29Å; R366-W368 VanDerWaalsContact C-N 3.25Å; R366-W368 PolarHBondContact O-N 3.14Å
369	S	82.3	Confident	71	Confident	69 Å²	69	93 Å²	93	48%	0.483	49%	0.492	S	S	.	.	H	α-helix	trans	-95.2	-51.8	-175.6	57.2	0	0	0	0	112.4	R365	R365-S369 PolarHBondContact O-N 2.88Å; R365-S369 PolarHBondContact O-OG 3.42Å
370	E	76.7	Confident	68.5	Low	105 Å²	105	96 Å²	96	49%	0.491	50%	0.502	S	S	.	.			trans	-147.6	77	-165.4	-70.2	178.3	-170.9	0	0	111.4	R366 F372 H373	R366-E370 CarbonylContact O-C 3.6Å; R366-E370 PolarHBondContact O-N 3.18Å; R366-E370 VanDerWaalsContact O-N 3.14Å; E370-F372 VanDerWaalsContact C-N 3.33Å; E370-F372 PolarHBondContact O-N 3.44Å; E370-H373 HydrophobicContact CB-CB 4.49Å; E370-H373 VanDerWaalsContact CD-ND1 3.31Å; E370-H373 IonicContact OE1-CE1 3.14Å; E370-H373 IonicContact OE2-CE1 2.72Å; E370-H373 PolarHBondContact OE2-CE1 3.47Å; E370-H373 IonicContact OE2-CG 2.69Å; E370-H373 IonicContact OE2-ND1 2.78Å; E370-H373 PolarHBondContact OE2-ND1 3.18Å
371	P	76	Confident	66.2	Low	4 Å²	4	98.1 Å²	98.1	3%	0.026	51%	0.506	C	S	.	.	T	Hydrogen-bonded Turn	trans	-66.4	-34	-176.4	19.5	-28.2	0	0	0	113.2	P184 F281 Y285 Y288 R366	P184-P371 WeakPolarHBondContact O-CG 3.4Å; F281-P371 HydrophobicContact CE2-CB 4.17Å; F281-P371 HydrophobicContact CE2-CG 3.66Å; F281-P371 HydrophobicContact CZ-CB 4.11Å; F281-P371 HydrophobicContact CZ-CG 3.85Å; Y285-P371 HydrophobicContact CD2-CB 3.55Å; Y285-P371 HydrophobicContact CE2-CB 3.81Å; Y288-P371 WeakPolarHBondContact CD1-O 3.08Å; Y288-P371 WeakPolarHBondContact CE1-O 3.49Å; R366-P371 WeakPolarHBondContact O-CA 3.46Å; R366-P371 VanDerWaalsContact O-N 3.15Å
372	F	77.6	Confident	64.1	Low	72 Å²	72	103.9 Å²	103.9	32%	0.316	54%	0.538	S	S	.	.	T	Hydrogen-bonded Turn	trans	-105.9	9.3	-168.4	-55.3	-65.2	0	0	0	115.2	F281 R284 Y288 E370 S374	F281-F372 HydrophobicContact CD2-CE2 4.3Å; F281-F372 HydrophobicContact CD2-CZ 4.27Å; F281-F372 AromaticContact CE2-CE2 3.97Å; F281-F372 HydrophobicContact CE2-CE2 3.97Å; F281-F372 HydrophobicContact CE2-CZ 4.1Å; R284-F372 HydrophobicContact CB-CE1 4.15Å; R284-F372 HydrophobicContact CB-CZ 3.98Å; Y288-F372 HydrophobicContact CD1-CD1 4.28Å; Y288-F372 HydrophobicContact CD2-CD1 4.47Å; Y288-F372 HydrophobicContact CG-CD1 4.06Å; E370-F372 VanDerWaalsContact C-N 3.33Å; E370-F372 PolarHBondContact O-N 3.44Å; F372-S374 PolarHBondContact O-N 2.98Å; F372-S374 VanDerWaalsContact O-N 3.16Å
373	H	61.5	Low	61.9	Low	111 Å²	111	108 Å²	108	51%	0.514	54%	0.541	S	S	.	.			trans	-66.4	119.4	173.4	-97.5	99	0	0	0	110	Y288 E370	Y288-H373 PolarHBondContact OH-O 2.83Å; E370-H373 HydrophobicContact CB-CB 4.49Å; E370-H373 VanDerWaalsContact CD-ND1 3.31Å; E370-H373 IonicContact OE1-CE1 3.14Å; E370-H373 IonicContact OE2-CE1 2.72Å; E370-H373 PolarHBondContact OE2-CE1 3.47Å; E370-H373 IonicContact OE2-CG 2.69Å; E370-H373 IonicContact OE2-ND1 2.78Å; E370-H373 PolarHBondContact OE2-ND1 3.18Å
374	S	51.3	Low	60.4	Low	84 Å²	84	116.5 Å²	116.5	59%	0.587	59%	0.593	S	S	*	*			trans	-56	138.7	154	53.2	0	0	0	0	106.4	Y288 F372 S376	Y288-S374 PolarHBondContact OH-N 3.46Å; F372-S374 PolarHBondContact O-N 2.98Å; F372-S374 VanDerWaalsContact O-N 3.16Å; S374-S376 VanDerWaalsContact C-N 3.33Å; S374-S376 PolarHBondContact O-N 3.2Å
375	K	40.3	Very low	59	Low	198 Å²	198	120 Å²	120	86%	0.861	61%	0.611	S	S	*	*			trans	-47.8	109.2	165.1	-71.2	178	-179.3	175.7	0	105.5	S377	K375-S377 VanDerWaalsContact C-N 3.26Å; K375-S377 PolarHBondContact O-N 2.93Å
376	S	34	Very low	57.4	Low	101 Å²	101	114.9 Å²	114.9	71%	0.706	60%	0.6	S	S	*	*			trans	-53.7	109.9	162.4	178.9	0	0	0	0	102.3	S374 S378	S374-S376 VanDerWaalsContact C-N 3.33Å; S374-S376 PolarHBondContact O-N 3.2Å; S376-S378 PolarHBondContact O-N 3.43Å
377	S	35.6	Very low	55.8	Low	109 Å²	109	116.2 Å²	116.2	76%	0.762	61%	0.614	S	S	*	*			trans	-51.6	107.4	168	-91.5	0	0	0	0	102.7	K375 S379	K375-S377 VanDerWaalsContact C-N 3.26Å; K375-S377 PolarHBondContact O-N 2.93Å; S377-S379 VanDerWaalsContact C-N 3.25Å; S377-S379 PolarHBondContact O-N 3.43Å
378	S	35.2	Very low	53.9	Low	107 Å²	107	123.1 Å²	123.1	75%	0.748	65%	0.65	S	S	*	*			trans	-45.5	105.2	175	-176.9	0	0	0	0	104	S376 R380	S376-S378 PolarHBondContact O-N 3.43Å; S378-R380 VanDerWaalsContact C-N 3.31Å; S378-R380 PolarHBondContact O-N 3.2Å
379	S	40.2	Very low	51.6	Low	104 Å²	104	124.1 Å²	124.1	73%	0.727	67%	0.666	S	S	*	*			trans	-54.2	110.5	178.9	44.2	0	0	0	0	103	S377 F381	S377-S379 VanDerWaalsContact C-N 3.25Å; S377-S379 PolarHBondContact O-N 3.43Å; S379-F381 PolarHBondContact O-N 3.06Å
380	R	38.9	Very low	49.6	Very low	234 Å²	234	127.8 Å²	127.8	88%	0.883	68%	0.678	S	S	*	*			trans	-41.2	116.5	-176.3	-86.5	-176.5	-99.6	175.1	-7	107.1	S378 L382	S378-R380 VanDerWaalsContact C-N 3.31Å; S378-R380 PolarHBondContact O-N 3.2Å; R380-L382 VanDerWaalsContact C-N 3.32Å; R380-L382 PolarHBondContact O-N 3.41Å
381	F	42.5	Very low	47.7	Very low	166 Å²	166	129.4 Å²	129.4	73%	0.728	69%	0.691	S	S	*	*			trans	-35.6	101.2	162	-153.5	-104.9	0	0	0	107.4	S379 E383	S379-F381 PolarHBondContact O-N 3.06Å; F381-E383 HydrophobicContact CD1-CB 3.78Å; F381-E383 HydrophobicContact CD1-CG 3.91Å; F381-E383 HydrophobicContact CE1-CB 3.66Å; F381-E383 HydrophobicContact CE1-CG 3.47Å; F381-E383 VanDerWaalsContact CE1-CG 3.47Å; F381-E383 WeakPolarHBondContact CE1-OE2 3.26Å; F381-E383 HydrophobicContact CZ-CG 3.95Å; F381-E383 PolarHBondContact O-N 2.86Å
382	L	41.4	Very low	45.5	Very low	166 Å²	166	139.1 Å²	139.1	87%	0.869	74%	0.743	S	S	*	*			trans	-94.5	64.9	173.5	-137	160.9	0	0	0	104.7	R380	R380-L382 VanDerWaalsContact C-N 3.32Å; R380-L382 PolarHBondContact O-N 3.41Å
383	E	38.2	Very low	42.8	Very low	148 Å²	148	144.7 Å²	144.7	69%	0.692	78%	0.778	S	S	*	*			trans	-99.5	108.2	155.2	-76.5	-162.9	165.9	0	0	106	F381	F381-E383 HydrophobicContact CD1-CB 3.78Å; F381-E383 HydrophobicContact CD1-CG 3.91Å; F381-E383 HydrophobicContact CE1-CB 3.66Å; F381-E383 HydrophobicContact CE1-CG 3.47Å; F381-E383 VanDerWaalsContact CE1-CG 3.47Å; F381-E383 WeakPolarHBondContact CE1-OE2 3.26Å; F381-E383 HydrophobicContact CZ-CG 3.95Å; F381-E383 PolarHBondContact O-N 2.86Å
384	V	54.8	Low	41.1	Very low	208 Å²	208	147.7 Å²	147.7	100%	1.261	80%	0.802	S	S	*	*			trans	-125.5	0	149.9	176.2	0	0	0	0	106.2

Retrieved 384 of 384 residues in 289 ms (Link to these results)

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