TWST2_HUMAN Loading...

Twist-related protein 2

Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of pro-inflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism (By similarity). Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.

AlphaFold DB , UniProt , Accession Q8WVJ9, Species HUMAN (Homo sapiens, Human), Gene TWIST2, Length 160 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	46.3	Very low	50.8	Low	233 Å²	233	137.5 Å²	137.5	100%	1.148	84%	0.837	S	S	*	*				0	118.5	0	-72.3	-178.4	-179.1	0	0	105.6	E3	M1-E3 PolarHBondContact O-N 3.21Å
2	E	47.2	Very low	51.6	Low	197 Å²	197	136.8 Å²	136.8	92%	0.921	83%	0.831	S	S	*	*			trans	-70.6	104.7	-177.2	-61.9	-78.9	120.2	0	0	108.3
3	E	50.2	Low	50.9	Low	182 Å²	182	137.1 Å²	137.1	85%	0.85	83%	0.826	S	S	*	*	P	Polyproline II helix	trans	-91.9	121.2	173.3	-76.2	-70.9	135.6	0	0	109	M1	M1-E3 PolarHBondContact O-N 3.21Å
4	G	43.2	Very low	51.1	Low	72 Å²	72	136.1 Å²	136.1	74%	0.742	83%	0.828	S	S	*	*	P	Polyproline II helix	trans	-66.9	140.8	-164.4	0	0	0	0	0	115.2	S6	G4-S6 PolarHBondContact O-N 3.49Å
5	S	45.6	Very low	50.7	Low	110 Å²	110	137.9 Å²	137.9	77%	0.769	83%	0.83	S	S	*	*	P	Polyproline II helix	trans	-54.2	118.2	158.8	153.2	0	0	0	0	111
6	S	51.1	Low	49.9	Very low	125 Å²	125	133.6 Å²	133.6	87%	0.874	82%	0.822	S	S	*	*			trans	-121.4	103.8	158.8	-155.7	0	0	0	0	108.5	G4	G4-S6 PolarHBondContact O-N 3.49Å
7	S	46.7	Very low	49.2	Very low	99 Å²	99	132.6 Å²	132.6	69%	0.692	82%	0.816	S	S	*	*	P	Polyproline II helix	trans	-84.2	162.5	-179.5	-82.7	0	0	0	0	111.3
8	P	54.5	Low	48.9	Very low	118 Å²	118	131.9 Å²	131.9	77%	0.766	82%	0.818	S	S	*	*	P	Polyproline II helix	trans	-92.4	153	-142.8	34.7	-34.9	0	0	0	115.1
9	V	58.2	Low	48.7	Very low	142 Å²	142	134.7 Å²	134.7	86%	0.861	82%	0.82	S	S	*	*	P	Polyproline II helix	trans	-74.5	122.6	170.1	40.9	0	0	0	0	110.5
10	S	51.3	Low	48.4	Very low	105 Å²	105	136.3 Å²	136.3	73%	0.734	82%	0.818	S	S	*	*	P	Polyproline II helix	trans	-66.5	133.9	178.1	-49.8	0	0	0	0	112.5
11	P	64.5	Low	47.8	Very low	130 Å²	130	139.2 Å²	139.2	84%	0.844	82%	0.823	S	S	*	*	P	Polyproline II helix	trans	-75.2	127.8	167.8	26.7	-26.8	0	0	0	110.7
12	V	60.9	Low	47.5	Very low	128 Å²	128	134.8 Å²	134.8	78%	0.776	80%	0.804	S	S	*	*	P	Polyproline II helix	trans	-69	144.1	178.6	52.4	0	0	0	0	112.3
13	D	42.6	Very low	47	Very low	141 Å²	141	133.7 Å²	133.7	75%	0.754	80%	0.798	S	S	*	*			trans	-40.4	125.9	177.8	-70.3	-70.7	0	0	0	115
14	S	53.5	Low	46.4	Very low	124 Å²	124	136.4 Å²	136.4	87%	0.867	80%	0.801	S	S	*	*			trans	-109.7	87.4	161.1	-69.3	0	0	0	0	108.7	G16	S14-G16 PolarHBondContact O-N 2.78Å; S14-G16 VanDerWaalsContact O-N 3.11Å
15	L	45.5	Very low	46.2	Very low	162 Å²	162	140.6 Å²	140.6	85%	0.848	80%	0.801	S	S	*	*			trans	-72.3	91	167	-83.1	153.9	0	0	0	108.8
16	G	38.1	Very low	46.1	Very low	69 Å²	69	140.5 Å²	140.5	71%	0.711	80%	0.798	S	S	*	*			trans	-122.9	71.7	173.1	0	0	0	0	0	110.6	S14	S14-G16 PolarHBondContact O-N 2.78Å; S14-G16 VanDerWaalsContact O-N 3.11Å
17	T	36.7	Very low	45.5	Very low	117 Å²	117	143 Å²	143	72%	0.718	79%	0.793	S	S	*	*			trans	-117.3	81.5	168.3	29.4	0	0	0	0	108.4
18	S	44.5	Very low	45.5	Very low	121 Å²	121	149.5 Å²	149.5	85%	0.846	80%	0.802	S	S	*	*			trans	-89.8	98.9	157.4	49.8	0	0	0	0	107.1	E20	S18-E20 PolarHBondContact O-N 2.97Å
19	E	44.9	Very low	44.9	Very low	184 Å²	184	152.6 Å²	152.6	86%	0.86	80%	0.804	S	S	*	*			trans	-73.2	110.3	172.6	-57.7	179.1	115.9	0	0	108.6
20	E	41.8	Very low	44.1	Very low	167 Å²	167	149.3 Å²	149.3	78%	0.78	80%	0.799	S	S	*	*			trans	-130.8	75.3	164.5	-135.5	-166.6	131.7	0	0	108.3	S18 L22	S18-E20 PolarHBondContact O-N 2.97Å; E20-L22 PolarHBondContact O-N 3.21Å
21	E	36.7	Very low	43.9	Very low	197 Å²	197	156.2 Å²	156.2	92%	0.921	81%	0.809	S	S	*	*			trans	-85.5	87.4	176.3	-168	171.1	123.8	0	0	109.2	E23	E21-E23 PolarHBondContact O-N 3.14Å
22	L	39.7	Very low	42.9	Very low	141 Å²	141	159.6 Å²	159.6	74%	0.738	81%	0.81	S	S	*	*			trans	-67.7	114.2	170.1	-83.3	159.6	0	0	0	110.2	E20 R24	E20-L22 PolarHBondContact O-N 3.21Å; L22-R24 PolarHBondContact O-N 2.98Å
23	E	36.1	Very low	42.1	Very low	174 Å²	174	165.4 Å²	165.4	81%	0.813	82%	0.818	S	S	*	*			trans	-33.4	103.2	172.4	-86.9	-160	108.9	0	0	113.9	E21 Q25	E21-E23 PolarHBondContact O-N 3.14Å; E23-Q25 PolarHBondContact O-N 3.24Å
24	R	39.2	Very low	42.2	Very low	239 Å²	239	170.1 Å²	170.1	90%	0.902	83%	0.826	S	S	*	*			trans	-90.5	94	160.6	-78.7	-175.7	178.8	169.8	1.8	109.4	L22 P26	L22-R24 PolarHBondContact O-N 2.98Å; R24-P26 WeakPolarHBondContact O-CD 3.31Å
25	Q	38.3	Very low	41.6	Very low	159 Å²	159	174.5 Å²	174.5	74%	0.743	83%	0.825	S	S	*	*			trans	-51.7	124.3	169.5	-85.3	-160.9	12.4	0	0	111.8	E23 K27	E23-Q25 PolarHBondContact O-N 3.24Å; Q25-K27 PolarHBondContact O-N 2.96Å
26	P	43	Very low	41.8	Very low	109 Å²	109	172.3 Å²	172.3	71%	0.708	82%	0.823	S	S	*	*			trans	-80.3	103.5	177.4	29.5	-31.5	0	0	0	111	R24 R28	R24-P26 WeakPolarHBondContact O-CD 3.31Å; P26-R28 VanDerWaalsContact C-N 3.31Å; P26-R28 HydrophobicContact CB-CG 4.49Å; P26-R28 PolarHBondContact O-N 2.67Å
27	K	40	Very low	42.1	Very low	177 Å²	177	177.9 Å²	177.9	77%	0.77	83%	0.828	S	S	*	*			trans	-67.5	86.3	166.2	-69.4	-167.3	-179.6	-178.3	0	110.3	Q25 F29	Q25-K27 PolarHBondContact O-N 2.96Å; K27-F29 VanDerWaalsContact C-N 3.35Å; K27-F29 HydrophobicContact CB-CD2 4.14Å; K27-F29 HydrophobicContact CB-CE2 4.02Å; K27-F29 HydrophobicContact CD-CE2 4.09Å; K27-F29 PolarHBondContact O-N 3.21Å
28	R	45.8	Very low	42.5	Very low	235 Å²	235	182 Å²	182	89%	0.887	84%	0.836	S	S	*	*			trans	-75.6	82.1	173.2	-59.3	-169.6	98	-178.9	8.2	110.1	P26 G30	P26-R28 VanDerWaalsContact C-N 3.31Å; P26-R28 HydrophobicContact CB-CG 4.49Å; P26-R28 PolarHBondContact O-N 2.67Å; R28-G30 PolarHBondContact O-N 2.76Å
29	F	42.2	Very low	42.3	Very low	183 Å²	183	180.5 Å²	180.5	80%	0.803	83%	0.826	S	S	*	*			trans	-71.2	118.3	166.1	-78.6	-82.7	0	0	0	109.7	K27 R31	K27-F29 VanDerWaalsContact C-N 3.35Å; K27-F29 HydrophobicContact CB-CD2 4.14Å; K27-F29 HydrophobicContact CB-CE2 4.02Å; K27-F29 HydrophobicContact CD-CE2 4.09Å; K27-F29 PolarHBondContact O-N 3.21Å; F29-R31 PolarHBondContact O-N 3.21Å
30	G	41.5	Very low	42.1	Very low	74 Å²	74	176.9 Å²	176.9	76%	0.763	82%	0.82	S	S	*	*			trans	-58.4	128.5	-172.9	0	0	0	0	0	113.8	R28 K32	R28-G30 PolarHBondContact O-N 2.76Å; G30-K32 PolarHBondContact O-N 3.03Å
31	R	46.4	Very low	42.2	Very low	249 Å²	249	177.7 Å²	177.7	94%	0.94	82%	0.824	S	S	*	*			trans	-75.5	102	166.1	-82.1	-179.6	169.3	173.7	-3.2	109.4	F29 R33	F29-R31 PolarHBondContact O-N 3.21Å; R31-R33 PolarHBondContact O-N 3.49Å
32	K	42.9	Very low	42.6	Very low	201 Å²	201	176.4 Å²	176.4	87%	0.874	82%	0.824	S	S	*	*			trans	-65.9	95.6	175.2	-156.6	170.4	-174	173	0	109.7	G30 R34	G30-K32 PolarHBondContact O-N 3.03Å; K32-R34 PolarHBondContact O-N 3.38Å; K32-R34 VanDerWaalsContact O-N 3.12Å
33	R	44.2	Very low	42.6	Very low	250 Å²	250	173 Å²	173	94%	0.943	82%	0.823	S	S	*	*			trans	-64.4	106.6	171.5	-97.7	-177.4	143.3	168.1	-5.3	109.2	R31 Y35	R31-R33 PolarHBondContact O-N 3.49Å; R33-Y35 PolarHBondContact O-N 2.87Å
34	R	45.4	Very low	42.9	Very low	240 Å²	240	170.4 Å²	170.4	91%	0.906	82%	0.824	S	S	*	*			trans	-74.4	115.8	168.4	-79.7	-175.2	173.1	-177.5	-1.5	109.1	K32	K32-R34 PolarHBondContact O-N 3.38Å; K32-R34 VanDerWaalsContact O-N 3.12Å
35	Y	40.6	Very low	43.3	Very low	216 Å²	216	164.5 Å²	164.5	85%	0.847	82%	0.817	S	S	*	*			trans	-76.1	114.8	166.8	-178.1	-95.8	0	0	0	107.8	R33	R33-Y35 PolarHBondContact O-N 2.87Å
36	S	50.9	Low	43.5	Very low	117 Å²	117	163.6 Å²	163.6	82%	0.818	82%	0.822	S	S	*	*			trans	-111.1	115.2	169.6	-160.9	0	0	0	0	109.6
37	K	42.9	Very low	43.6	Very low	185 Å²	185	164.6 Å²	164.6	80%	0.804	83%	0.828	S	S	*	*			trans	-57.1	129.9	178.1	-179.6	174.1	179.2	168.4	0	111.2
38	K	45.1	Very low	43.7	Very low	203 Å²	203	159.5 Å²	159.5	88%	0.883	83%	0.826	S	S	*	*			trans	-132.3	124.4	161	-157.3	161.5	-176.2	176.5	0	110.1
39	S	40.7	Very low	43.6	Very low	91 Å²	91	158.5 Å²	158.5	64%	0.636	83%	0.828	S	S	*	*			trans	-51.2	139	179.9	42.2	0	0	0	0	113.5
40	S	41.4	Very low	43.8	Very low	107 Å²	107	161.8 Å²	161.8	75%	0.748	84%	0.836	S	S	*	*				55.9	122.1	99.5	-40.9	0	0	0	0	111
41	E	43.9	Very low	44.1	Very low	184 Å²	184	161.5 Å²	161.5	86%	0.86	83%	0.832	S	S	*	*				-162.6	135.9	53.9	-70.1	177.3	108.2	0	0	108.7
42	D	43.6	Very low	44.1	Very low	171 Å²	171	159.5 Å²	159.5	91%	0.914	83%	0.83	S	S	*	*				97.4	128	113.1	-168.2	33.5	0	0	0	113.9
43	G	40.4	Very low	44.4	Very low	70 Å²	70	160.2 Å²	160.2	72%	0.722	83%	0.833	S	S	*	*			trans	139.4	68.3	-175.4	0	0	0	0	0	116
44	S	42.4	Very low	44.8	Very low	119 Å²	119	151.3 Å²	151.3	83%	0.832	82%	0.82	S	S	*	*			trans	27.5	141.8	152.8	-148.4	0	0	0	0	123.4
45	P	48	Very low	45.3	Very low	115 Å²	115	144.5 Å²	144.5	75%	0.747	81%	0.809	S	S	*	*			trans	-102.7	151.9	-162.6	38.7	-28.4	0	0	0	114.8
46	T	42.6	Very low	46.3	Very low	140 Å²	140	140.1 Å²	140.1	86%	0.859	81%	0.807	S	S	*	*			trans	-120.7	139	152	53.7	0	0	0	0	110.5
47	P	45.2	Very low	46.7	Very low	129 Å²	129	139 Å²	139	84%	0.838	80%	0.799	S	S	*	*			trans	-102.4	145.1	-160.9	36.2	-27.1	0	0	0	113.2
48	G	41.4	Very low	48	Very low	71 Å²	71	135 Å²	135	73%	0.732	80%	0.8	S	S	*	*				95.1	80.6	129.5	0	0	0	0	0	118
49	K	43.9	Very low	49.5	Very low	213 Å²	213	130.3 Å²	130.3	93%	0.926	78%	0.782	S	S	*	*				-149.1	89.6	125.9	-120	172.9	-178.1	177.8	0	109.3	G51	K49-G51 PolarHBondContact O-N 2.75Å
50	R	47.5	Very low	51.8	Low	253 Å²	253	128.2 Å²	128.2	96%	0.955	77%	0.767	S	S	*	*			trans	-69.5	78.3	170.8	-67.2	170.3	96.1	172.3	5.7	107.8	K52	R50-K52 PolarHBondContact O-N 3.48Å; R50-K52 VanDerWaalsContact O-N 3.16Å
51	G	48	Very low	54.2	Low	67 Å²	67	130.8 Å²	130.8	69%	0.691	77%	0.765	S	S	*	*			trans	-59	116.1	162.7	0	0	0	0	0	107.6	K49 K53	K49-G51 PolarHBondContact O-N 2.75Å; G51-K53 PolarHBondContact O-N 3.5Å
52	K	46.3	Very low	56.6	Low	207 Å²	207	128.2 Å²	128.2	90%	0.9	75%	0.753	S	S	*	*			trans	-27.5	120.1	174.1	-103	162.6	167.7	172.5	0	110.8	R50 G54	R50-K52 PolarHBondContact O-N 3.48Å; R50-K52 VanDerWaalsContact O-N 3.16Å; K52-G54 PolarHBondContact O-N 2.96Å
53	K	48	Very low	59.1	Low	216 Å²	216	124.7 Å²	124.7	94%	0.939	73%	0.731	S	S	*	*			trans	-60.2	83.3	164.9	-74.8	177.2	174.2	179.3	0	107.3	G51 S55	G51-K53 PolarHBondContact O-N 3.5Å; K53-S55 PolarHBondContact O-N 3.4Å; K53-S55 VanDerWaalsContact O-N 3.14Å
54	G	52.3	Low	61.7	Low	64 Å²	64	125.5 Å²	125.5	66%	0.66	72%	0.718	S	S	*	*			trans	-55.2	118.2	161.1	0	0	0	0	0	105.6	K52	K52-G54 PolarHBondContact O-N 2.96Å
55	S	56.3	Low	64.3	Low	96 Å²	96	123.3 Å²	123.3	67%	0.671	70%	0.695	S	S	*	*			trans	-39.8	135.1	163.9	178.2	0	0	0	0	107.7	K53 S57	K53-S55 PolarHBondContact O-N 3.4Å; K53-S55 VanDerWaalsContact O-N 3.14Å; S55-S57 PolarHBondContact O-N 3.03Å
56	P	61	Low	66.5	Low	124 Å²	124	121 Å²	121	81%	0.805	68%	0.682	S	S	*	*			trans	-65.2	78.7	172.9	27.8	-31.1	0	0	0	107.3	A58	P56-A58 PolarHBondContact O-N 2.89Å; P56-A58 VanDerWaalsContact O-N 3.16Å
57	S	60.2	Low	69.1	Low	95 Å²	95	119 Å²	119	66%	0.664	66%	0.662	S	S	*	*			trans	-54	122.4	170.2	50.6	0	0	0	0	104.7	S55 Q59	S55-S57 PolarHBondContact O-N 3.03Å; S57-Q59 PolarHBondContact O-N 3.33Å
58	A	69.2	Low	71.6	Confident	100 Å²	100	120.5 Å²	120.5	83%	0.826	65%	0.652	S	S	*	*			trans	-35.9	100.8	-178.6	0	0	0	0	0	109.4	P56 S60	P56-A58 PolarHBondContact O-N 2.89Å; P56-A58 VanDerWaalsContact O-N 3.16Å; A58-S60 PolarHBondContact O-N 3.27Å
59	Q	77.1	Confident	74.3	Confident	104 Å²	104	121.6 Å²	121.6	49%	0.486	64%	0.639	S	S	.	*			trans	-56.5	134.4	178.7	-72.4	179.9	-56.6	0	0	106.2	S57 L64	S57-Q59 PolarHBondContact O-N 3.33Å; Q59-L64 HydrophobicContact CB-CD1 3.3Å; Q59-L64 HydrophobicContact CG-CD1 4.45Å
60	S	89.7	Confident	76.9	Confident	48 Å²	48	117.3 Å²	117.3	34%	0.336	63%	0.626	S	S	.	*			trans	-59.4	148.8	-178.9	66.1	0	0	0	0	109.6	A58 E62 E63 L64	A58-S60 PolarHBondContact O-N 3.27Å; S60-E62 PolarHBondContact O-N 3.41Å; S60-E63 WeakPolarHBondContact O-CB 3.3Å; S60-E63 PolarHBondContact O-N 3.16Å; S60-E63 VanDerWaalsContact OG-CG 3.22Å; S60-E63 WeakPolarHBondContact OG-CG 3.37Å; S60-E63 PolarHBondContact OG-N 3.25Å; S60-E63 PolarHBondContact OG-OE1 2.9Å; S60-L64 WeakPolarHBondContact O-CD1 2.86Å; S60-L64 PolarHBondContact O-N 3.37Å; S60-L64 VanDerWaalsContact O-N 3.11Å
61	F	92.1	Very high	79.3	Confident	160 Å²	160	108 Å²	108	70%	0.702	60%	0.603	S	S	*	*	H	α-helix	trans	-54.8	-38.6	178.7	174.9	-97.3	0	0	0	111.7	L64 Q65	F61-L64 PolarHBondContact O-N 3.21Å; F61-Q65 PolarHBondContact O-N 2.98Å
62	E	94.5	Very high	81.7	Confident	131 Å²	131	109.6 Å²	109.6	61%	0.612	60%	0.596	S	S	*	*	H	α-helix	trans	-55.7	-47.1	172.2	-74.5	-77.1	154.9	0	0	112.9	S60 Q65 S66	S60-E62 PolarHBondContact O-N 3.41Å; E62-Q65 PolarHBondContact O-N 3.17Å; E62-S66 WeakPolarHBondContact O-CB 3.37Å; E62-S66 PolarHBondContact O-N 2.79Å; E62-S66 PolarHBondContact O-OG 3.3Å
63	E	94.5	Very high	84.2	Confident	96 Å²	96	103 Å²	103	45%	0.449	57%	0.572	S	S	.	*	H	α-helix	trans	-64.3	-40.9	176.8	-77.7	158.3	-131	0	0	112.1	S60 Q65 S66 Q67	S60-E63 WeakPolarHBondContact O-CB 3.3Å; S60-E63 PolarHBondContact O-N 3.16Å; S60-E63 VanDerWaalsContact OG-CG 3.22Å; S60-E63 WeakPolarHBondContact OG-CG 3.37Å; S60-E63 PolarHBondContact OG-N 3.25Å; S60-E63 PolarHBondContact OG-OE1 2.9Å; E63-Q65 VanDerWaalsContact C-N 3.33Å; E63-S66 PolarHBondContact O-N 2.87Å; E63-Q67 WeakPolarHBondContact O-CB 3.25Å; E63-Q67 VanDerWaalsContact O-CG 3.32Å; E63-Q67 WeakPolarHBondContact O-CG 3.43Å; E63-Q67 PolarHBondContact O-N 2.76Å; E63-Q67 PolarHBondContact O-NE2 3Å
64	L	95.3	Very high	86.6	Confident	87 Å²	87	101.7 Å²	101.7	46%	0.455	56%	0.562	S	S	.	*	H	α-helix	trans	-62	-43.6	175.3	-91.2	78.7	0	0	0	111.1	Q59 S60 F61 S66 Q67 R68	Q59-L64 HydrophobicContact CB-CD1 3.3Å; Q59-L64 HydrophobicContact CG-CD1 4.45Å; S60-L64 WeakPolarHBondContact O-CD1 2.86Å; S60-L64 PolarHBondContact O-N 3.37Å; S60-L64 VanDerWaalsContact O-N 3.11Å; F61-L64 PolarHBondContact O-N 3.21Å; L64-S66 VanDerWaalsContact C-N 3.35Å; L64-Q67 PolarHBondContact O-N 2.91Å; L64-R68 WeakPolarHBondContact O-CB 3.42Å; L64-R68 PolarHBondContact O-N 3Å
65	Q	96.5	Very high	88.8	Confident	74 Å²	74	102.9 Å²	102.9	35%	0.346	55%	0.55	S	S	.	*	H	α-helix	trans	-63.6	-43.4	178.5	-176.9	169.4	1.2	0	0	111	F61 E62 E63 R68 I69	F61-Q65 PolarHBondContact O-N 2.98Å; E62-Q65 PolarHBondContact O-N 3.17Å; E63-Q65 VanDerWaalsContact C-N 3.33Å; Q65-R68 WeakPolarHBondContact O-CB 3.14Å; Q65-R68 PolarHBondContact O-N 2.9Å; Q65-I69 HydrophobicContact CG-CD1 4.16Å; Q65-I69 WeakPolarHBondContact O-CG1 3.47Å; Q65-I69 PolarHBondContact O-N 2.99Å
66	S	96	Very high	90.8	Very high	67 Å²	67	107.1 Å²	107.1	47%	0.469	55%	0.551	S	S	.	*	H	α-helix	trans	-60.9	-45.6	176.8	-63	0	0	0	0	112.3	E62 E63 L64 R68 I69 L70	E62-S66 WeakPolarHBondContact O-CB 3.37Å; E62-S66 PolarHBondContact O-N 2.79Å; E62-S66 PolarHBondContact O-OG 3.3Å; E63-S66 PolarHBondContact O-N 2.87Å; L64-S66 VanDerWaalsContact C-N 3.35Å; S66-R68 VanDerWaalsContact C-N 3.32Å; S66-R68 PolarHBondContact O-N 3.45Å; S66-I69 PolarHBondContact O-N 3.45Å; S66-L70 PolarHBondContact O-N 2.87Å
67	Q	97.1	Very high	92.6	Very high	96 Å²	96	106.8 Å²	106.8	45%	0.449	54%	0.539	S	S	.	.	H	α-helix	trans	-62.2	-40	175.2	-74.4	171.7	53.3	0	0	112.1	E63 L64 L70 A71	E63-Q67 WeakPolarHBondContact O-CB 3.25Å; E63-Q67 VanDerWaalsContact O-CG 3.32Å; E63-Q67 WeakPolarHBondContact O-CG 3.43Å; E63-Q67 PolarHBondContact O-N 2.76Å; E63-Q67 PolarHBondContact O-NE2 3Å; L64-Q67 PolarHBondContact O-N 2.91Å; Q67-L70 PolarHBondContact O-N 3.23Å; Q67-A71 WeakPolarHBondContact O-CB 3.42Å; Q67-A71 PolarHBondContact O-N 3.32Å
68	R	97.1	Very high	94.4	Very high	162 Å²	162	110.3 Å²	110.3	61%	0.611	54%	0.538	S	S	*	.	H	α-helix	trans	-62.8	-42.6	176.1	-171.5	177.9	73.3	160	1.5	111.5	L64 Q65 S66 A71 N72	L64-R68 WeakPolarHBondContact O-CB 3.42Å; L64-R68 PolarHBondContact O-N 3Å; Q65-R68 WeakPolarHBondContact O-CB 3.14Å; Q65-R68 PolarHBondContact O-N 2.9Å; S66-R68 VanDerWaalsContact C-N 3.32Å; S66-R68 PolarHBondContact O-N 3.45Å; R68-A71 PolarHBondContact O-N 2.7Å; R68-N72 VanDerWaalsContact O-CG 3.26Å; R68-N72 PolarHBondContact O-N 3.4Å; R68-N72 PolarHBondContact O-ND2 3.38Å
69	I	98	Very high	95.8	Very high	93 Å²	93	108.4 Å²	108.4	48%	0.477	52%	0.516	S	S	.	.	H	α-helix	trans	-62.1	-48.4	176.5	-67.6	164.5	0	0	0	110.1	Q65 S66 A71 N72 V73	Q65-I69 HydrophobicContact CG-CD1 4.16Å; Q65-I69 WeakPolarHBondContact O-CG1 3.47Å; Q65-I69 PolarHBondContact O-N 2.99Å; S66-I69 PolarHBondContact O-N 3.45Å; I69-A71 VanDerWaalsContact C-N 3.31Å; I69-A71 PolarHBondContact O-N 3.38Å; I69-N72 WeakPolarHBondContact O-CB 3.41Å; I69-N72 PolarHBondContact O-N 3Å; I69-N72 VanDerWaalsContact O-N 3.14Å; I69-V73 WeakPolarHBondContact O-CG2 3.44Å; I69-V73 PolarHBondContact O-N 3.39Å
70	L	97.8	Very high	96.9	Very high	124 Å²	124	107.8 Å²	107.8	65%	0.649	51%	0.513	S	S	*	.	H	α-helix	trans	-60.7	-40.4	179.2	-176.2	62.4	0	0	0	112.2	S66 Q67 V73 R74	S66-L70 PolarHBondContact O-N 2.87Å; Q67-L70 PolarHBondContact O-N 3.23Å; L70-V73 PolarHBondContact O-N 2.98Å; L70-R74 PolarHBondContact O-N 3.43Å
71	A	97.8	Very high	97.3	Very high	56 Å²	56	109 Å²	109	46%	0.463	52%	0.522	S	S	.	.	H	α-helix	trans	-62.2	-43.2	175	0	0	0	0	0	112.1	Q67 R68 I69 R74 E75	Q67-A71 WeakPolarHBondContact O-CB 3.42Å; Q67-A71 PolarHBondContact O-N 3.32Å; R68-A71 PolarHBondContact O-N 2.7Å; I69-A71 VanDerWaalsContact C-N 3.31Å; I69-A71 PolarHBondContact O-N 3.38Å; A71-R74 PolarHBondContact O-N 3.34Å; A71-E75 PolarHBondContact O-N 2.94Å
72	N	98.6	Very high	97.6	Very high	101 Å²	101	105.5 Å²	105.5	54%	0.54	51%	0.51	S	S	.	.	H	α-helix	trans	-62.9	-42.1	176.5	-71.6	-17	0	0	0	112	R68 I69 R74 E75 R76	R68-N72 VanDerWaalsContact O-CG 3.26Å; R68-N72 PolarHBondContact O-N 3.4Å; R68-N72 PolarHBondContact O-ND2 3.38Å; I69-N72 WeakPolarHBondContact O-CB 3.41Å; I69-N72 PolarHBondContact O-N 3Å; I69-N72 VanDerWaalsContact O-N 3.14Å; N72-R74 VanDerWaalsContact C-N 3.32Å; N72-R74 PolarHBondContact O-N 3.15Å; N72-E75 PolarHBondContact O-N 3.27Å; N72-R76 PolarHBondContact O-N 3.41Å
73	V	98.6	Very high	97.8	Very high	68 Å²	68	102.4 Å²	102.4	41%	0.412	50%	0.497	S	S	.	.	H	α-helix	trans	-59	-45.4	175.2	171.2	0	0	0	0	110.6	I69 L70 E75 R76 Q77	I69-V73 WeakPolarHBondContact O-CG2 3.44Å; I69-V73 PolarHBondContact O-N 3.39Å; L70-V73 PolarHBondContact O-N 2.98Å; V73-E75 PolarHBondContact O-N 2.89Å; V73-R76 WeakPolarHBondContact O-CB 3.38Å; V73-R76 PolarHBondContact O-N 2.98Å; V73-Q77 WeakPolarHBondContact O-CG 3.45Å; V73-Q77 PolarHBondContact O-N 3.26Å
74	R	98.6	Very high	98	Very high	190 Å²	190	103 Å²	103	72%	0.717	50%	0.501	S	S	*	.	H	α-helix	trans	-62.2	-42.3	178.1	-172.5	179.7	-178.5	176.1	1.3	112.5	L70 A71 N72 R76 Q77 R78	L70-R74 PolarHBondContact O-N 3.43Å; A71-R74 PolarHBondContact O-N 3.34Å; N72-R74 VanDerWaalsContact C-N 3.32Å; N72-R74 PolarHBondContact O-N 3.15Å; R74-R76 VanDerWaalsContact C-N 3.32Å; R74-R76 PolarHBondContact O-N 2.92Å; R74-Q77 PolarHBondContact O-N 3.38Å; R74-R78 PolarHBondContact O-N 2.91Å
75	E	98.6	Very high	98.1	Very high	89 Å²	89	101.9 Å²	101.9	42%	0.416	50%	0.503	S	S	.	.	H	α-helix	trans	-66.9	-35.3	178.1	-170.5	58.4	-151.2	0	0	111.8	A71 N72 V73 R78 T79	A71-E75 PolarHBondContact O-N 2.94Å; N72-E75 PolarHBondContact O-N 3.27Å; V73-E75 PolarHBondContact O-N 2.89Å; E75-R78 PolarHBondContact O-N 3.5Å; E75-R78 IonicContact OE1-CZ 3.86Å; E75-R78 IonicContact OE1-NH1 3.87Å; E75-R78 PolarHBondContact OE1-NH1 3.25Å; E75-R78 IonicContact OE2-NH1 2.79Å; E75-R78 PolarHBondContact OE2-NH1 2.98Å; E75-T79 WeakPolarHBondContact O-CB 3.31Å; E75-T79 PolarHBondContact O-N 3.35Å; E75-T79 PolarHBondContact O-OG1 2.99Å
76	R	98.7	Very high	98.2	Very high	184 Å²	184	99.8 Å²	99.8	69%	0.694	49%	0.493	S	S	*	.	H	α-helix	trans	-62.1	-44.8	172.3	-170.2	-179.4	-172.8	-85.5	2.6	111.5	N72 V73 R74 T79 Q80	N72-R76 PolarHBondContact O-N 3.41Å; V73-R76 WeakPolarHBondContact O-CB 3.38Å; V73-R76 PolarHBondContact O-N 2.98Å; R74-R76 VanDerWaalsContact C-N 3.32Å; R74-R76 PolarHBondContact O-N 2.92Å; R76-T79 PolarHBondContact O-N 3.4Å; R76-Q80 WeakPolarHBondContact O-CB 3.31Å; R76-Q80 PolarHBondContact O-N 3.42Å
77	Q	98.7	Very high	98.3	Very high	117 Å²	117	98.8 Å²	98.8	55%	0.547	49%	0.489	S	S	.	.	H	α-helix	trans	-62.1	-43.4	176.4	-72	174.8	-11.2	0	0	112	V73 R74 T79 Q80 S81	V73-Q77 WeakPolarHBondContact O-CG 3.45Å; V73-Q77 PolarHBondContact O-N 3.26Å; R74-Q77 PolarHBondContact O-N 3.38Å; Q77-T79 VanDerWaalsContact C-N 3.33Å; Q77-T79 PolarHBondContact O-N 2.95Å; Q77-Q80 WeakPolarHBondContact O-CB 3.5Å; Q77-Q80 PolarHBondContact O-N 2.93Å; Q77-S81 PolarHBondContact O-N 2.97Å
78	R	98.7	Very high	98.4	Very high	169 Å²	169	96.9 Å²	96.9	64%	0.638	49%	0.489	S	S	*	.	H	α-helix	trans	-58.4	-45.7	174.3	-179.4	-174.5	171.6	-140.6	1.9	111.6	R74 E75 Q80 S81 L82	R74-R78 PolarHBondContact O-N 2.91Å; E75-R78 PolarHBondContact O-N 3.5Å; E75-R78 IonicContact OE1-CZ 3.86Å; E75-R78 IonicContact OE1-NH1 3.87Å; E75-R78 PolarHBondContact OE1-NH1 3.25Å; E75-R78 IonicContact OE2-NH1 2.79Å; E75-R78 PolarHBondContact OE2-NH1 2.98Å; R78-Q80 VanDerWaalsContact C-N 3.34Å; R78-S81 PolarHBondContact O-N 3.38Å; R78-L82 PolarHBondContact O-N 3.21Å; R78-L82 VanDerWaalsContact O-N 3.09Å
79	T	98.7	Very high	98.4	Very high	61 Å²	61	91.5 Å²	91.5	37%	0.374	47%	0.472	S	S	.	.	H	α-helix	trans	-65.2	-38.1	178	-59.2	0	0	0	0	111.9	E75 R76 Q77 L82 N83	E75-T79 WeakPolarHBondContact O-CB 3.31Å; E75-T79 PolarHBondContact O-N 3.35Å; E75-T79 PolarHBondContact O-OG1 2.99Å; R76-T79 PolarHBondContact O-N 3.4Å; Q77-T79 VanDerWaalsContact C-N 3.33Å; Q77-T79 PolarHBondContact O-N 2.95Å; T79-L82 PolarHBondContact O-N 3.4Å; T79-N83 VanDerWaalsContact O-CG 3.29Å; T79-N83 PolarHBondContact O-N 3.37Å; T79-N83 PolarHBondContact O-ND2 2.91Å
80	Q	98.7	Very high	98.4	Very high	91 Å²	91	90.8 Å²	90.8	43%	0.425	46%	0.464	S	S	.	.	H	α-helix	trans	-60.5	-50.5	174.4	179.3	-177.5	-11.6	0	0	111.3	R76 Q77 R78 L82 N83 E84	R76-Q80 WeakPolarHBondContact O-CB 3.31Å; R76-Q80 PolarHBondContact O-N 3.42Å; Q77-Q80 WeakPolarHBondContact O-CB 3.5Å; Q77-Q80 PolarHBondContact O-N 2.93Å; R78-Q80 VanDerWaalsContact C-N 3.34Å; Q80-L82 VanDerWaalsContact C-N 3.28Å; Q80-L82 PolarHBondContact O-N 3.16Å; Q80-N83 WeakPolarHBondContact O-CB 3.39Å; Q80-N83 PolarHBondContact O-N 3.16Å; Q80-E84 WeakPolarHBondContact CG-OE1 3.44Å; Q80-E84 PolarHBondContact NE2-OE1 3.16Å; Q80-E84 WeakPolarHBondContact O-CG 3.3Å; Q80-E84 PolarHBondContact O-N 3.37Å
81	S	98.5	Very high	98.3	Very high	74 Å²	74	93.5 Å²	93.5	52%	0.517	47%	0.47	S	S	.	.	H	α-helix	trans	-57.1	-41.3	177.4	175.7	0	0	0	0	112.2	Q77 R78 N83 E84 A85	Q77-S81 PolarHBondContact O-N 2.97Å; R78-S81 PolarHBondContact O-N 3.38Å; S81-N83 PolarHBondContact O-N 3.05Å; S81-E84 PolarHBondContact O-N 3.33Å; S81-A85 PolarHBondContact O-N 2.86Å
82	L	98.5	Very high	98.3	Very high	86 Å²	86	96.3 Å²	96.3	45%	0.45	48%	0.477	S	S	.	.	H	α-helix	trans	-62.1	-41.8	174.1	-178.8	153.6	0	0	0	112	R78 T79 Q80 E84 A85 F86	R78-L82 PolarHBondContact O-N 3.21Å; R78-L82 VanDerWaalsContact O-N 3.09Å; T79-L82 PolarHBondContact O-N 3.4Å; Q80-L82 VanDerWaalsContact C-N 3.28Å; Q80-L82 PolarHBondContact O-N 3.16Å; L82-E84 VanDerWaalsContact C-N 3.35Å; L82-A85 PolarHBondContact O-N 3.45Å; L82-F86 HydrophobicContact CD2-CD2 3.64Å; L82-F86 HydrophobicContact CD2-CE2 3.75Å; L82-F86 HydrophobicContact CG-CD2 4.39Å; L82-F86 HydrophobicContact CG-CE2 4.47Å; L82-F86 WeakPolarHBondContact O-CD2 3.3Å; L82-F86 PolarHBondContact O-N 2.89Å
83	N	98.4	Very high	98.1	Very high	65 Å²	65	92 Å²	92	35%	0.348	45%	0.453	S	S	.	.	H	α-helix	trans	-68.1	-35.2	178.9	-70.8	-28.2	0	0	0	112.2	T79 Q80 S81 F86 A87 K103	T79-N83 VanDerWaalsContact O-CG 3.29Å; T79-N83 PolarHBondContact O-N 3.37Å; T79-N83 PolarHBondContact O-ND2 2.91Å; Q80-N83 WeakPolarHBondContact O-CB 3.39Å; Q80-N83 PolarHBondContact O-N 3.16Å; S81-N83 PolarHBondContact O-N 3.05Å; N83-F86 WeakPolarHBondContact O-CB 3.36Å; N83-F86 PolarHBondContact O-N 3.49Å; N83-A87 PolarHBondContact O-N 2.83Å; N83-K103 VanDerWaalsContact OD1-CE 3.32Å; N83-K103 WeakPolarHBondContact OD1-CE 3.34Å; N83-K103 PolarHBondContact OD1-NZ 3.11Å
84	E	98.7	Very high	97.9	Very high	110 Å²	110	90.1 Å²	90.1	51%	0.514	44%	0.442	S	S	.	.	H	α-helix	trans	-62.6	-42.6	172.9	-71.6	169.1	-170.9	0	0	111.2	Q80 S81 L82 F86 A87 A88	Q80-E84 WeakPolarHBondContact CG-OE1 3.44Å; Q80-E84 PolarHBondContact NE2-OE1 3.16Å; Q80-E84 WeakPolarHBondContact O-CG 3.3Å; Q80-E84 PolarHBondContact O-N 3.37Å; S81-E84 PolarHBondContact O-N 3.33Å; L82-E84 VanDerWaalsContact C-N 3.35Å; E84-F86 VanDerWaalsContact C-N 3.34Å; E84-F86 PolarHBondContact O-N 3.11Å; E84-A87 WeakPolarHBondContact O-CB 3.47Å; E84-A87 PolarHBondContact O-N 2.81Å; E84-A87 VanDerWaalsContact O-N 3.08Å; E84-A88 PolarHBondContact O-N 2.96Å
85	A	98.6	Very high	97.5	Very high	62 Å²	62	82.9 Å²	82.9	51%	0.512	42%	0.42	S	S	.	.	H	α-helix	trans	-61.4	-40.9	173.4	0	0	0	0	0	112.3	S81 L82 A87 A88 L89	S81-A85 PolarHBondContact O-N 2.86Å; L82-A85 PolarHBondContact O-N 3.45Å; A85-A87 VanDerWaalsContact C-N 3.31Å; A85-A87 PolarHBondContact O-N 3.4Å; A85-A88 PolarHBondContact O-N 3.39Å; A85-L89 WeakPolarHBondContact O-CB 3.36Å; A85-L89 PolarHBondContact O-N 2.98Å
86	F	98.6	Very high	97.1	Very high	31 Å²	31	83.6 Å²	83.6	14%	0.136	43%	0.425	C	S	.	.	H	α-helix	trans	-62.4	-37.3	171.9	-97.1	-81.4	0	0	0	112.4	L82 N83 E84 R90 K103 T106 L107	L82-F86 HydrophobicContact CD2-CD2 3.64Å; L82-F86 HydrophobicContact CD2-CE2 3.75Å; L82-F86 HydrophobicContact CG-CD2 4.39Å; L82-F86 HydrophobicContact CG-CE2 4.47Å; L82-F86 WeakPolarHBondContact O-CD2 3.3Å; L82-F86 PolarHBondContact O-N 2.89Å; N83-F86 WeakPolarHBondContact O-CB 3.36Å; N83-F86 PolarHBondContact O-N 3.49Å; E84-F86 VanDerWaalsContact C-N 3.34Å; E84-F86 PolarHBondContact O-N 3.11Å; F86-R90 VanDerWaalsContact C-NH1 3.27Å; F86-R90 WeakPolarHBondContact O-CG 3.1Å; F86-R90 PolarHBondContact O-N 3.49Å; F86-R90 VanDerWaalsContact O-N 3.11Å; F86-R90 PolarHBondContact O-NH1 2.81Å; F86-R90 VanDerWaalsContact O-NH1 3.11Å; F86-K103 HydrophobicContact CD1-CB 4.31Å; F86-K103 HydrophobicContact CD1-CG 4.11Å; F86-K103 HydrophobicContact CE1-CB 3.72Å; F86-K103 HydrophobicContact CE1-CG 3.96Å; F86-K103 HydrophobicContact CE2-CD 4.28Å; F86-K103 HydrophobicContact CE2-CG 4.44Å; F86-K103 HydrophobicContact CG-CG 4.43Å; F86-K103 HydrophobicContact CZ-CB 3.94Å; F86-K103 HydrophobicContact CZ-CD 4.32Å; F86-K103 HydrophobicContact CZ-CG 4.13Å; F86-T106 HydrophobicContact CD1-CG2 4.27Å; F86-L107 HydrophobicContact CE1-CD1 4.48Å; F86-L107 HydrophobicContact CE1-CD2 4.19Å; F86-L107 HydrophobicContact CE1-CG 4.04Å; F86-L107 HydrophobicContact CZ-CD1 4.2Å; F86-L107 HydrophobicContact CZ-CD2 4.22Å; F86-L107 HydrophobicContact CZ-CG 4.19Å
87	A	98	Very high	96.7	Very high	46 Å²	46	81.1 Å²	81.1	38%	0.38	43%	0.433	S	S	.	.	H	α-helix	trans	-67.2	-41.9	176.3	0	0	0	0	0	111.4	N83 E84 A85 R90 K91	N83-A87 PolarHBondContact O-N 2.83Å; E84-A87 WeakPolarHBondContact O-CB 3.47Å; E84-A87 PolarHBondContact O-N 2.81Å; E84-A87 VanDerWaalsContact O-N 3.08Å; A85-A87 VanDerWaalsContact C-N 3.31Å; A85-A87 PolarHBondContact O-N 3.4Å; A87-R90 PolarHBondContact O-N 2.9Å; A87-K91 PolarHBondContact O-N 3.3Å
88	A	98.3	Very high	96.2	Very high	55 Å²	55	79.6 Å²	79.6	46%	0.455	44%	0.436	S	S	.	.	H	α-helix	trans	-61.5	-45.1	174.1	0	0	0	0	0	111.7	E84 A85 R90 K91	E84-A88 PolarHBondContact O-N 2.96Å; A85-A88 PolarHBondContact O-N 3.39Å; A88-R90 VanDerWaalsContact C-N 3.35Å; A88-R90 PolarHBondContact O-N 3.12Å; A88-K91 WeakPolarHBondContact O-CB 3.37Å; A88-K91 PolarHBondContact O-N 3.33Å; A88-K91 VanDerWaalsContact O-N 3.16Å
89	L	98.4	Very high	95.8	Very high	49 Å²	49	74.3 Å²	74.3	26%	0.257	42%	0.42	S	S	.	.	H	α-helix	trans	-58.1	-45.2	176.8	-178.2	57.9	0	0	0	111.6	A85 K91 I92 I93 T106 A110	A85-L89 WeakPolarHBondContact O-CB 3.36Å; A85-L89 PolarHBondContact O-N 2.98Å; L89-K91 PolarHBondContact O-N 2.92Å; L89-K91 VanDerWaalsContact O-N 3.16Å; L89-I92 HydrophobicContact CD1-CD1 4.12Å; L89-I92 HydrophobicContact CD1-CG1 4.22Å; L89-I92 WeakPolarHBondContact O-CG1 3.42Å; L89-I92 PolarHBondContact O-N 3.39Å; L89-I92 VanDerWaalsContact O-N 3.11Å; L89-I93 HydrophobicContact CD1-CD1 3.95Å; L89-I93 HydrophobicContact CG-CD1 4.21Å; L89-I93 HydrophobicContact CG-CG1 4.49Å; L89-I93 WeakPolarHBondContact O-CG1 3.42Å; L89-I93 PolarHBondContact O-N 3.11Å; L89-T106 HydrophobicContact CB-CG2 4.34Å; L89-T106 HydrophobicContact CD2-CG2 3.74Å; L89-T106 HydrophobicContact CG-CG2 3.82Å; L89-A110 HydrophobicContact CD1-CB 4.28Å; L89-A110 HydrophobicContact CD2-CB 4.35Å
90	R	97.1	Very high	95.5	Very high	79 Å²	79	80.2 Å²	80.2	30%	0.298	44%	0.44	S	S	.	.	H	α-helix	trans	-57.9	-29.8	178.6	-73.9	-176.7	-163.4	92.2	-6.8	113.9	F86 A87 A88 I92 I93 L101 T106	F86-R90 VanDerWaalsContact C-NH1 3.27Å; F86-R90 WeakPolarHBondContact O-CG 3.1Å; F86-R90 PolarHBondContact O-N 3.49Å; F86-R90 VanDerWaalsContact O-N 3.11Å; F86-R90 PolarHBondContact O-NH1 2.81Å; F86-R90 VanDerWaalsContact O-NH1 3.11Å; A87-R90 PolarHBondContact O-N 2.9Å; A88-R90 VanDerWaalsContact C-N 3.35Å; A88-R90 PolarHBondContact O-N 3.12Å; R90-I92 PolarHBondContact O-N 3.34Å; R90-I93 PolarHBondContact O-N 2.91Å; R90-L101 HydrophobicContact CG-CB 4.44Å; R90-L101 HydrophobicContact CG-CD1 4.49Å; R90-L101 PolarHBondContact NE-O 3.46Å; R90-L101 PolarHBondContact NH2-O 2.91Å; R90-T106 HydrophobicContact CG-CG2 3.75Å; R90-T106 PolarHBondContact NE-OG1 3.42Å
91	K	96.6	Very high	95.3	Very high	181 Å²	181	76.9 Å²	76.9	79%	0.787	43%	0.425	S	S	*	.	H	α-helix	trans	-66	-25.5	180	-66.7	178.7	179	-178.1	0	113.3	A87 A88 L89	A87-K91 PolarHBondContact O-N 3.3Å; A88-K91 WeakPolarHBondContact O-CB 3.37Å; A88-K91 PolarHBondContact O-N 3.33Å; A88-K91 VanDerWaalsContact O-N 3.16Å; L89-K91 PolarHBondContact O-N 2.92Å; L89-K91 VanDerWaalsContact O-N 3.16Å
92	I	96.7	Very high	95.2	Very high	115 Å²	115	75.6 Å²	75.6	59%	0.59	42%	0.417	S	S	*	.	H	α-helix	trans	-104.1	-4.1	-178.5	63.5	163.1	0	0	0	112.7	L89 R90	L89-I92 HydrophobicContact CD1-CD1 4.12Å; L89-I92 HydrophobicContact CD1-CG1 4.22Å; L89-I92 WeakPolarHBondContact O-CG1 3.42Å; L89-I92 PolarHBondContact O-N 3.39Å; L89-I92 VanDerWaalsContact O-N 3.11Å; R90-I92 PolarHBondContact O-N 3.34Å
93	I	95.2	Very high	95.1	Very high	10 Å²	10	76 Å²	76	5%	0.051	42%	0.415	C	S	.	.	S	Bend	trans	-77.2	128.1	172.8	-54.7	-48	0	0	0	108	L89 R90 T95 L101 T106 L109 A110	L89-I93 HydrophobicContact CD1-CD1 3.95Å; L89-I93 HydrophobicContact CG-CD1 4.21Å; L89-I93 HydrophobicContact CG-CG1 4.49Å; L89-I93 WeakPolarHBondContact O-CG1 3.42Å; L89-I93 PolarHBondContact O-N 3.11Å; R90-I93 PolarHBondContact O-N 2.91Å; I93-T95 VanDerWaalsContact C-N 3.35Å; I93-T95 HydrophobicContact CG2-CG2 3.85Å; I93-T95 PolarHBondContact O-N 3.33Å; I93-L101 HydrophobicContact CB-CD1 4.33Å; I93-L101 HydrophobicContact CG2-CD1 4.13Å; I93-T106 HydrophobicContact CG1-CG2 4.31Å; I93-L109 HydrophobicContact CG2-CB 3.57Å; I93-L109 HydrophobicContact CG2-CD1 4.06Å; I93-L109 HydrophobicContact CG2-CG 4.38Å; I93-A110 HydrophobicContact CD1-CB 3.69Å
94	P	93.4	Very high	95.1	Very high	28 Å²	28	77.8 Å²	77.8	18%	0.182	42%	0.423	C	S	.	.			trans	-78.8	80.9	-174.6	33.7	-38.8	0	0	0	112	Y113 F145 W148	P94-Y113 HydrophobicContact CG-CD1 4.26Å; P94-Y113 HydrophobicContact CG-CD2 3.72Å; P94-Y113 HydrophobicContact CG-CE1 4.36Å; P94-Y113 HydrophobicContact CG-CE2 3.85Å; P94-Y113 HydrophobicContact CG-CG 3.95Å; P94-F145 HydrophobicContact CB-CE2 3.55Å; P94-F145 HydrophobicContact CB-CZ 3.57Å; P94-F145 HydrophobicContact CG-CE2 3.82Å; P94-F145 HydrophobicContact CG-CZ 4.3Å; P94-W148 HydrophobicContact CG-CH2 4.04Å; P94-W148 HydrophobicContact CG-CZ3 3.79Å
95	T	90.9	Very high	94.9	Very high	39 Å²	39	77 Å²	77	24%	0.239	42%	0.419	C	S	.	.			trans	-122.3	174.7	178.2	60.7	0	0	0	0	112.7	I93 D99 L101 L109	I93-T95 VanDerWaalsContact C-N 3.35Å; I93-T95 HydrophobicContact CG2-CG2 3.85Å; I93-T95 PolarHBondContact O-N 3.33Å; T95-D99 WeakPolarHBondContact CB-OD2 2.97Å; T95-L101 HydrophobicContact CG2-CD1 3.87Å; T95-L101 HydrophobicContact CG2-CD2 4.28Å; T95-L101 HydrophobicContact CG2-CG 4.48Å; T95-L109 HydrophobicContact CG2-CD1 3.89Å
96	L	90.4	Very high	94.8	Very high	103 Å²	103	74 Å²	74	54%	0.539	40%	0.395	S	S	.	.			trans	-71.6	149.4	173	-60.5	173	0	0	0	110.4	S98 D99	L96-S98 PolarHBondContact O-N 2.89Å; L96-S98 VanDerWaalsContact O-N 3.12Å; L96-D99 WeakPolarHBondContact CB-OD2 3.34Å; L96-D99 PolarHBondContact N-OD2 3.08Å; L96-D99 WeakPolarHBondContact O-CB 3.4Å; L96-D99 PolarHBondContact O-N 3.45Å
97	P	88.8	Confident	94.8	Very high	133 Å²	133	76.8 Å²	76.8	86%	0.864	41%	0.411	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.4	-26.3	178.1	-26	34.9	0	0	0	114.5	D99	P97-D99 VanDerWaalsContact C-N 3.32Å
98	S	90	Very high	94.6	Very high	85 Å²	85	79.5 Å²	79.5	59%	0.594	41%	0.414	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74.4	-19.7	176.2	50	0	0	0	0	113.6	L96 K100	L96-S98 PolarHBondContact O-N 2.89Å; L96-S98 VanDerWaalsContact O-N 3.12Å; S98-K100 PolarHBondContact O-N 3.38Å
99	D	90.3	Very high	94.5	Very high	58 Å²	58	77.4 Å²	77.4	31%	0.31	40%	0.395	S	S	.	.			trans	-71.5	126.9	-167	-65.8	-16.9	0	0	0	111.6	T95 L96 P97	T95-D99 WeakPolarHBondContact CB-OD2 2.97Å; L96-D99 WeakPolarHBondContact CB-OD2 3.34Å; L96-D99 PolarHBondContact N-OD2 3.08Å; L96-D99 WeakPolarHBondContact O-CB 3.4Å; L96-D99 PolarHBondContact O-N 3.45Å; P97-D99 VanDerWaalsContact C-N 3.32Å
100	K	92.2	Very high	94.4	Very high	184 Å²	184	75.7 Å²	75.7	80%	0.8	39%	0.388	S	S	*	.			trans	-103.4	93.1	176.5	-60	-56.2	-179.5	-169.6	0	109.9	S98 S102	S98-K100 PolarHBondContact O-N 3.38Å; K100-S102 PolarHBondContact O-N 3.44Å
101	L	93.6	Very high	94.4	Very high	21 Å²	21	74.2 Å²	74.2	11%	0.11	39%	0.393	C	S	.	.			trans	-79.6	120.5	-179.4	-56.1	180	0	0	0	111.9	R90 I93 T95 Q105 T106 L109	R90-L101 HydrophobicContact CG-CB 4.44Å; R90-L101 HydrophobicContact CG-CD1 4.49Å; R90-L101 PolarHBondContact NE-O 3.46Å; R90-L101 PolarHBondContact NH2-O 2.91Å; I93-L101 HydrophobicContact CB-CD1 4.33Å; I93-L101 HydrophobicContact CG2-CD1 4.13Å; T95-L101 HydrophobicContact CG2-CD1 3.87Å; T95-L101 HydrophobicContact CG2-CD2 4.28Å; T95-L101 HydrophobicContact CG2-CG 4.48Å; L101-Q105 HydrophobicContact CB-CB 4.43Å; L101-Q105 HydrophobicContact CD2-CB 4.33Å; L101-T106 WeakPolarHBondContact CB-OG1 3.41Å; L101-L109 HydrophobicContact CD1-CD1 3.78Å; L101-L109 HydrophobicContact CD2-CD1 3.62Å; L101-L109 HydrophobicContact CG-CD1 4.34Å
102	S	96.6	Very high	94.3	Very high	48 Å²	48	68.5 Å²	68.5	34%	0.336	37%	0.366	S	S	.	.			trans	-60.9	166.9	163.9	67.7	0	0	0	0	111.2	K100 I104 Q105 T106	K100-S102 PolarHBondContact O-N 3.44Å; S102-I104 VanDerWaalsContact C-N 3.31Å; S102-I104 PolarHBondContact O-N 3.11Å; S102-I104 WeakPolarHBondContact OG-CG2 3.35Å; S102-Q105 PolarHBondContact O-N 2.88Å; S102-Q105 WeakPolarHBondContact OG-CB 3.28Å; S102-Q105 VanDerWaalsContact OG-CG 3.3Å; S102-Q105 WeakPolarHBondContact OG-CG 3.39Å; S102-Q105 PolarHBondContact OG-N 3.04Å; S102-Q105 PolarHBondContact OG-OE1 2.79Å; S102-T106 WeakPolarHBondContact O-CB 3.45Å; S102-T106 PolarHBondContact O-N 2.89Å; S102-T106 PolarHBondContact O-OG1 2.97Å
103	K	97.3	Very high	94.3	Very high	95 Å²	95	66.2 Å²	66.2	41%	0.413	35%	0.351	S	S	.	.	H	α-helix	trans	-58.1	-44.7	178.5	-68.5	-174.8	177.4	-174.3	0	111.5	N83 F86 T106 L107	N83-K103 VanDerWaalsContact OD1-CE 3.32Å; N83-K103 WeakPolarHBondContact OD1-CE 3.34Å; N83-K103 PolarHBondContact OD1-NZ 3.11Å; F86-K103 HydrophobicContact CD1-CB 4.31Å; F86-K103 HydrophobicContact CD1-CG 4.11Å; F86-K103 HydrophobicContact CE1-CB 3.72Å; F86-K103 HydrophobicContact CE1-CG 3.96Å; F86-K103 HydrophobicContact CE2-CD 4.28Å; F86-K103 HydrophobicContact CE2-CG 4.44Å; F86-K103 HydrophobicContact CG-CG 4.43Å; F86-K103 HydrophobicContact CZ-CB 3.94Å; F86-K103 HydrophobicContact CZ-CD 4.32Å; F86-K103 HydrophobicContact CZ-CG 4.13Å; K103-T106 PolarHBondContact O-N 3.34Å; K103-L107 WeakPolarHBondContact O-CG 3.38Å; K103-L107 PolarHBondContact O-N 3.34Å
104	I	97	Very high	94.4	Very high	102 Å²	102	71 Å²	71	52%	0.523	38%	0.376	S	S	.	.	H	α-helix	trans	-67.1	-41.7	-179.7	-173.4	60.1	0	0	0	112.2	S102 T106 L107 K108	S102-I104 VanDerWaalsContact C-N 3.31Å; S102-I104 PolarHBondContact O-N 3.11Å; S102-I104 WeakPolarHBondContact OG-CG2 3.35Å; I104-T106 VanDerWaalsContact C-N 3.35Å; I104-T106 PolarHBondContact O-N 3.3Å; I104-L107 PolarHBondContact O-N 2.92Å; I104-K108 HydrophobicContact CG1-CD 4.48Å; I104-K108 WeakPolarHBondContact O-CG 3.48Å; I104-K108 PolarHBondContact O-N 3.09Å
105	Q	94.7	Very high	94.6	Very high	92 Å²	92	73.9 Å²	73.9	43%	0.43	39%	0.389	S	S	.	.	H	α-helix	trans	-63.6	-42.2	176.7	-74.2	166.9	-49.4	0	0	111.6	L101 S102 L107 K108 L109	L101-Q105 HydrophobicContact CB-CB 4.43Å; L101-Q105 HydrophobicContact CD2-CB 4.33Å; S102-Q105 PolarHBondContact O-N 2.88Å; S102-Q105 WeakPolarHBondContact OG-CB 3.28Å; S102-Q105 VanDerWaalsContact OG-CG 3.3Å; S102-Q105 WeakPolarHBondContact OG-CG 3.39Å; S102-Q105 PolarHBondContact OG-N 3.04Å; S102-Q105 PolarHBondContact OG-OE1 2.79Å; Q105-L107 VanDerWaalsContact C-N 3.3Å; Q105-L107 PolarHBondContact O-N 3.32Å; Q105-K108 PolarHBondContact O-N 3.07Å; Q105-L109 WeakPolarHBondContact O-CB 3.4Å; Q105-L109 WeakPolarHBondContact O-CG 3.44Å; Q105-L109 PolarHBondContact O-N 3.4Å
106	T	97	Very high	94.7	Very high	0 Å²	0	72.7 Å²	72.7	0%	0	38%	0.381	C	S	.	.	H	α-helix	trans	-56.9	-46.2	177.5	-52.9	0	0	0	0	110.5	F86 L89 R90 I93 L101 S102 K103 I104 A110	F86-T106 HydrophobicContact CD1-CG2 4.27Å; L89-T106 HydrophobicContact CB-CG2 4.34Å; L89-T106 HydrophobicContact CD2-CG2 3.74Å; L89-T106 HydrophobicContact CG-CG2 3.82Å; R90-T106 HydrophobicContact CG-CG2 3.75Å; R90-T106 PolarHBondContact NE-OG1 3.42Å; I93-T106 HydrophobicContact CG1-CG2 4.31Å; L101-T106 WeakPolarHBondContact CB-OG1 3.41Å; S102-T106 WeakPolarHBondContact O-CB 3.45Å; S102-T106 PolarHBondContact O-N 2.89Å; S102-T106 PolarHBondContact O-OG1 2.97Å; K103-T106 PolarHBondContact O-N 3.34Å; I104-T106 VanDerWaalsContact C-N 3.35Å; I104-T106 PolarHBondContact O-N 3.3Å; T106-A110 VanDerWaalsContact O-CB 3.28Å; T106-A110 WeakPolarHBondContact O-CB 3.41Å; T106-A110 PolarHBondContact O-N 2.97Å
107	L	98	Very high	95	Very high	90 Å²	90	70.8 Å²	70.8	47%	0.471	37%	0.371	S	S	.	.	H	α-helix	trans	-66	-45.9	178.5	-65.7	173.9	0	0	0	112.4	F86 K103 I104 Q105 L109 A110 A111	F86-L107 HydrophobicContact CE1-CD1 4.48Å; F86-L107 HydrophobicContact CE1-CD2 4.19Å; F86-L107 HydrophobicContact CE1-CG 4.04Å; F86-L107 HydrophobicContact CZ-CD1 4.2Å; F86-L107 HydrophobicContact CZ-CD2 4.22Å; F86-L107 HydrophobicContact CZ-CG 4.19Å; K103-L107 WeakPolarHBondContact O-CG 3.38Å; K103-L107 PolarHBondContact O-N 3.34Å; I104-L107 PolarHBondContact O-N 2.92Å; Q105-L107 VanDerWaalsContact C-N 3.3Å; Q105-L107 PolarHBondContact O-N 3.32Å; L107-L109 VanDerWaalsContact C-N 3.32Å; L107-L109 PolarHBondContact O-N 3.4Å; L107-A110 PolarHBondContact O-N 3Å; L107-A111 PolarHBondContact O-N 3.06Å
108	K	95.3	Very high	95.3	Very high	102 Å²	102	72 Å²	72	44%	0.443	36%	0.359	S	S	.	.	H	α-helix	trans	-62	-38.6	178.4	-76.7	-174.5	171.2	-172.4	0	112.6	I104 Q105 R112	I104-K108 HydrophobicContact CG1-CD 4.48Å; I104-K108 WeakPolarHBondContact O-CG 3.48Å; I104-K108 PolarHBondContact O-N 3.09Å; Q105-K108 PolarHBondContact O-N 3.07Å; K108-R112 WeakPolarHBondContact O-CG 3.39Å; K108-R112 PolarHBondContact O-N 3.39Å; K108-R112 PolarHBondContact O-NE 3.46Å; K108-R112 VanDerWaalsContact O-NE 3.11Å
109	L	94.6	Very high	95.5	Very high	11 Å²	11	74.2 Å²	74.2	6%	0.058	36%	0.36	C	S	.	.	H	α-helix	trans	-72.8	-40.7	176.6	-75.2	168.5	0	0	0	111.5	I93 T95 L101 Q105 L107 A111 R112 Y113 W154	I93-L109 HydrophobicContact CG2-CB 3.57Å; I93-L109 HydrophobicContact CG2-CD1 4.06Å; I93-L109 HydrophobicContact CG2-CG 4.38Å; T95-L109 HydrophobicContact CG2-CD1 3.89Å; L101-L109 HydrophobicContact CD1-CD1 3.78Å; L101-L109 HydrophobicContact CD2-CD1 3.62Å; L101-L109 HydrophobicContact CG-CD1 4.34Å; Q105-L109 WeakPolarHBondContact O-CB 3.4Å; Q105-L109 WeakPolarHBondContact O-CG 3.44Å; Q105-L109 PolarHBondContact O-N 3.4Å; L107-L109 VanDerWaalsContact C-N 3.32Å; L107-L109 PolarHBondContact O-N 3.4Å; L109-A111 PolarHBondContact O-N 3.34Å; L109-R112 PolarHBondContact O-N 2.76Å; L109-Y113 VanDerWaalsContact O-CB 3.3Å; L109-Y113 WeakPolarHBondContact O-CB 3.48Å; L109-Y113 PolarHBondContact O-N 3.29Å; L109-W154 HydrophobicContact CD2-CB 3.72Å; L109-W154 HydrophobicContact CD2-CD2 4.39Å; L109-W154 HydrophobicContact CD2-CE3 4.33Å; L109-W154 HydrophobicContact CD2-CG 4.2Å
110	A	97.4	Very high	95.6	Very high	13 Å²	13	72.7 Å²	72.7	11%	0.107	35%	0.353	C	S	.	.	H	α-helix	trans	-57.7	-49.2	175.5	0	0	0	0	0	111.9	L89 I93 T106 L107 R112 Y113 I114	L89-A110 HydrophobicContact CD1-CB 4.28Å; L89-A110 HydrophobicContact CD2-CB 4.35Å; I93-A110 HydrophobicContact CD1-CB 3.69Å; T106-A110 VanDerWaalsContact O-CB 3.28Å; T106-A110 WeakPolarHBondContact O-CB 3.41Å; T106-A110 PolarHBondContact O-N 2.97Å; L107-A110 PolarHBondContact O-N 3Å; A110-R112 PolarHBondContact O-N 3.28Å; A110-Y113 PolarHBondContact O-N 2.99Å; A110-I114 WeakPolarHBondContact O-CG1 3.48Å; A110-I114 PolarHBondContact O-N 3.38Å
111	A	96.9	Very high	95.6	Very high	49 Å²	49	69.4 Å²	69.4	41%	0.405	34%	0.344	S	S	.	.	H	α-helix	trans	-57.4	-50.3	178.4	0	0	0	0	0	111.7	L107 L109 Y113 I114 D115	L107-A111 PolarHBondContact O-N 3.06Å; L109-A111 PolarHBondContact O-N 3.34Å; A111-Y113 VanDerWaalsContact C-N 3.29Å; A111-Y113 PolarHBondContact O-N 3Å; A111-I114 WeakPolarHBondContact O-CB 3.47Å; A111-I114 PolarHBondContact O-N 3.34Å; A111-I114 VanDerWaalsContact O-N 3.16Å; A111-D115 PolarHBondContact O-N 3.18Å
112	R	94.3	Very high	95.4	Very high	61 Å²	61	72.4 Å²	72.4	23%	0.23	36%	0.357	C	S	.	.	H	α-helix	trans	-65.9	-31	178.6	-72	-177.2	-69.1	-175.7	-6.4	113.9	K108 L109 A110 D115 F116 W148 A153 W154	K108-R112 WeakPolarHBondContact O-CG 3.39Å; K108-R112 PolarHBondContact O-N 3.39Å; K108-R112 PolarHBondContact O-NE 3.46Å; K108-R112 VanDerWaalsContact O-NE 3.11Å; L109-R112 PolarHBondContact O-N 2.76Å; A110-R112 PolarHBondContact O-N 3.28Å; R112-D115 PolarHBondContact O-N 3.49Å; R112-F116 WeakPolarHBondContact O-CB 3.44Å; R112-F116 PolarHBondContact O-N 3.41Å; R112-W148 HydrophobicContact CB-CZ2 4Å; R112-A153 PolarHBondContact NH1-O 3.48Å; R112-W154 VanDerWaalsContact CZ-CB 3.5Å; R112-W154 VanDerWaalsContact NH1-CB 3.32Å; R112-W154 VanDerWaalsContact NH1-N 3.15Å
113	Y	96.5	Very high	94.8	Very high	66 Å²	66	73.1 Å²	73.1	26%	0.259	36%	0.362	S	S	.	.	H	α-helix	trans	-69.7	-38	175.8	-175.5	-136.2	0	0	0	110.9	P94 L109 A110 A111 F116 L117 W148	P94-Y113 HydrophobicContact CG-CD1 4.26Å; P94-Y113 HydrophobicContact CG-CD2 3.72Å; P94-Y113 HydrophobicContact CG-CE1 4.36Å; P94-Y113 HydrophobicContact CG-CE2 3.85Å; P94-Y113 HydrophobicContact CG-CG 3.95Å; L109-Y113 VanDerWaalsContact O-CB 3.3Å; L109-Y113 WeakPolarHBondContact O-CB 3.48Å; L109-Y113 PolarHBondContact O-N 3.29Å; A110-Y113 PolarHBondContact O-N 2.99Å; A111-Y113 VanDerWaalsContact C-N 3.29Å; A111-Y113 PolarHBondContact O-N 3Å; Y113-F116 AromaticContact CD2-CD1 3.93Å; Y113-F116 HydrophobicContact CD2-CD1 3.93Å; Y113-F116 AromaticContact CE2-CD1 3.97Å; Y113-F116 HydrophobicContact CE2-CD1 3.97Å; Y113-F116 HydrophobicContact CE2-CE1 4.37Å; Y113-F116 PolarHBondContact O-N 2.95Å; Y113-L117 HydrophobicContact CD1-CD1 4.32Å; Y113-L117 HydrophobicContact CD2-CD1 4.4Å; Y113-L117 HydrophobicContact CD2-CG 4.16Å; Y113-L117 HydrophobicContact CE1-CD1 3.93Å; Y113-L117 HydrophobicContact CE2-CD1 3.99Å; Y113-L117 HydrophobicContact CE2-CD2 3.87Å; Y113-L117 HydrophobicContact CE2-CG 3.81Å; Y113-L117 VanDerWaalsContact O-CG 3.31Å; Y113-L117 WeakPolarHBondContact O-CG 3.48Å; Y113-L117 PolarHBondContact O-N 2.77Å; Y113-W148 HydrophobicContact CD2-CH2 4.32Å
114	I	97.5	Very high	94.1	Very high	112 Å²	112	71.6 Å²	71.6	57%	0.574	36%	0.359	S	S	*	.	H	α-helix	trans	-59.4	-49.2	169.9	-65.4	163.3	0	0	0	110.1	A110 A111 F116 L117 Y118	A110-I114 WeakPolarHBondContact O-CG1 3.48Å; A110-I114 PolarHBondContact O-N 3.38Å; A111-I114 WeakPolarHBondContact O-CB 3.47Å; A111-I114 PolarHBondContact O-N 3.34Å; A111-I114 VanDerWaalsContact O-N 3.16Å; I114-F116 VanDerWaalsContact C-N 3.29Å; I114-F116 PolarHBondContact O-N 3.29Å; I114-L117 PolarHBondContact O-N 3.48Å; I114-Y118 WeakPolarHBondContact O-CB 3.49Å; I114-Y118 PolarHBondContact O-N 2.95Å
115	D	96.4	Very high	93.2	Very high	88 Å²	88	72.3 Å²	72.3	47%	0.471	36%	0.36	S	S	.	.	H	α-helix	trans	-60.8	-38.9	179.9	-61.7	-30	0	0	0	112.3	A111 R112 Y118 Q119	A111-D115 PolarHBondContact O-N 3.18Å; R112-D115 PolarHBondContact O-N 3.49Å; D115-Y118 PolarHBondContact O-N 3.39Å; D115-Q119 WeakPolarHBondContact O-CG 3.46Å; D115-Q119 PolarHBondContact O-N 3.44Å; D115-Q119 PolarHBondContact O-NE2 3.02Å
116	F	94.8	Very high	92.2	Very high	14 Å²	14	74.8 Å²	74.8	6%	0.061	37%	0.373	C	S	.	.	H	α-helix	trans	-62.9	-51.1	174.9	167.4	-105.6	0	0	0	111.9	R112 Y113 I114 Y118 Q119 V120 A144 F145 W148	R112-F116 WeakPolarHBondContact O-CB 3.44Å; R112-F116 PolarHBondContact O-N 3.41Å; Y113-F116 AromaticContact CD2-CD1 3.93Å; Y113-F116 HydrophobicContact CD2-CD1 3.93Å; Y113-F116 AromaticContact CE2-CD1 3.97Å; Y113-F116 HydrophobicContact CE2-CD1 3.97Å; Y113-F116 HydrophobicContact CE2-CE1 4.37Å; Y113-F116 PolarHBondContact O-N 2.95Å; I114-F116 VanDerWaalsContact C-N 3.29Å; I114-F116 PolarHBondContact O-N 3.29Å; F116-Y118 PolarHBondContact O-N 3.35Å; F116-Q119 PolarHBondContact O-N 3.4Å; F116-Q119 VanDerWaalsContact O-N 3.15Å; F116-V120 HydrophobicContact CD1-CG2 4.5Å; F116-V120 HydrophobicContact CD2-CG2 4.13Å; F116-V120 HydrophobicContact CE1-CG2 4.05Å; F116-V120 HydrophobicContact CE2-CG2 3.64Å; F116-V120 HydrophobicContact CZ-CG2 3.59Å; F116-V120 WeakPolarHBondContact O-CG2 3.42Å; F116-V120 PolarHBondContact O-N 3.24Å; F116-A144 HydrophobicContact CE2-CB 4.18Å; F116-A144 HydrophobicContact CZ-CB 4.3Å; F116-F145 HydrophobicContact CE1-CB 4.43Å; F116-F145 HydrophobicContact CE1-CD2 4.06Å; F116-F145 HydrophobicContact CZ-CB 3.96Å; F116-F145 HydrophobicContact CZ-CD2 4.3Å; F116-W148 HydrophobicContact CB-CD2 4.24Å; F116-W148 HydrophobicContact CB-CG 4.15Å; F116-W148 HydrophobicContact CB-CZ2 4.44Å; F116-W148 HydrophobicContact CD2-CB 3.61Å; F116-W148 AromaticContact CD2-CD1 3.49Å; F116-W148 VanDerWaalsContact CD2-CD1 3.49Å; F116-W148 HydrophobicContact CD2-CD2 4.17Å; F116-W148 AromaticContact CD2-CG 3.46Å; F116-W148 HydrophobicContact CD2-CG 3.46Å; F116-W148 VanDerWaalsContact CD2-CG 3.46Å; F116-W148 HydrophobicContact CE2-CB 3.64Å; F116-W148 AromaticContact CE2-CG 3.99Å; F116-W148 HydrophobicContact CE2-CG 3.99Å; F116-W148 HydrophobicContact CG-CB 4.37Å; F116-W148 AromaticContact CG-CD1 3.79Å; F116-W148 HydrophobicContact CG-CD2 4.05Å; F116-W148 AromaticContact CG-CG 3.81Å; F116-W148 HydrophobicContact CG-CG 3.81Å; F116-W148 AromaticContact CG-NE1 3.99Å; F116-W148 HydrophobicContact CZ-CB 4.43Å
117	L	95.8	Very high	91	Very high	63 Å²	63	78.3 Å²	78.3	33%	0.33	39%	0.392	S	S	.	.	H	α-helix	trans	-61.6	-37.3	179.4	-68.8	177.2	0	0	0	111.3	Y113 I114 V120 L121	Y113-L117 HydrophobicContact CD1-CD1 4.32Å; Y113-L117 HydrophobicContact CD2-CD1 4.4Å; Y113-L117 HydrophobicContact CD2-CG 4.16Å; Y113-L117 HydrophobicContact CE1-CD1 3.93Å; Y113-L117 HydrophobicContact CE2-CD1 3.99Å; Y113-L117 HydrophobicContact CE2-CD2 3.87Å; Y113-L117 HydrophobicContact CE2-CG 3.81Å; Y113-L117 VanDerWaalsContact O-CG 3.31Å; Y113-L117 WeakPolarHBondContact O-CG 3.48Å; Y113-L117 PolarHBondContact O-N 2.77Å; I114-L117 PolarHBondContact O-N 3.48Å; L117-V120 PolarHBondContact O-N 3.06Å; L117-L121 VanDerWaalsContact O-CG 3.31Å; L117-L121 WeakPolarHBondContact O-CG 3.38Å; L117-L121 PolarHBondContact O-N 3.31Å
118	Y	96.1	Very high	89.8	Confident	157 Å²	157	78.8 Å²	78.8	62%	0.616	40%	0.395	S	S	*	.	H	α-helix	trans	-60.5	-46.4	174.1	-173.2	-93.3	0	0	0	112.1	I114 D115 F116 L121 Q122	I114-Y118 WeakPolarHBondContact O-CB 3.49Å; I114-Y118 PolarHBondContact O-N 2.95Å; D115-Y118 PolarHBondContact O-N 3.39Å; F116-Y118 PolarHBondContact O-N 3.35Å; Y118-L121 PolarHBondContact O-N 3.28Å; Y118-Q122 PolarHBondContact O-N 3.24Å
119	Q	93.1	Very high	88.6	Confident	133 Å²	133	83.6 Å²	83.6	62%	0.621	42%	0.416	S	S	*	.	H	α-helix	trans	-63.4	-41.7	176.7	-73.2	173.6	61.3	0	0	112.6	D115 F116 Q122 S123	D115-Q119 WeakPolarHBondContact O-CG 3.46Å; D115-Q119 PolarHBondContact O-N 3.44Å; D115-Q119 PolarHBondContact O-NE2 3.02Å; F116-Q119 PolarHBondContact O-N 3.4Å; F116-Q119 VanDerWaalsContact O-N 3.15Å; Q119-Q122 PolarHBondContact O-N 2.84Å; Q119-S123 PolarHBondContact O-N 3.39Å; Q119-S123 PolarHBondContact O-OG 3.27Å
120	V	92.5	Very high	87.4	Confident	26 Å²	26	87.7 Å²	87.7	16%	0.158	44%	0.436	C	S	.	.	H	α-helix	trans	-59.7	-48.5	176.5	170.8	0	0	0	0	110.4	F116 L117 Q122 S123 D124 L141	F116-V120 HydrophobicContact CD1-CG2 4.5Å; F116-V120 HydrophobicContact CD2-CG2 4.13Å; F116-V120 HydrophobicContact CE1-CG2 4.05Å; F116-V120 HydrophobicContact CE2-CG2 3.64Å; F116-V120 HydrophobicContact CZ-CG2 3.59Å; F116-V120 WeakPolarHBondContact O-CG2 3.42Å; F116-V120 PolarHBondContact O-N 3.24Å; L117-V120 PolarHBondContact O-N 3.06Å; V120-Q122 VanDerWaalsContact C-N 3.35Å; V120-Q122 PolarHBondContact O-N 3.37Å; V120-S123 PolarHBondContact O-N 3.38Å; V120-S123 PolarHBondContact O-OG 2.88Å; V120-D124 PolarHBondContact O-N 2.91Å; V120-L141 HydrophobicContact CG1-CD1 4.43Å
121	L	91.2	Very high	86.3	Confident	115 Å²	115	88.5 Å²	88.5	60%	0.602	44%	0.439	S	S	*	.	H	α-helix	trans	-61	-42.6	177.8	-70.7	171.3	0	0	0	112.2	L117 Y118 S123 D124 E125	L117-L121 VanDerWaalsContact O-CG 3.31Å; L117-L121 WeakPolarHBondContact O-CG 3.38Å; L117-L121 PolarHBondContact O-N 3.31Å; Y118-L121 PolarHBondContact O-N 3.28Å; L121-S123 VanDerWaalsContact C-N 3.3Å; L121-S123 PolarHBondContact O-N 2.94Å; L121-D124 WeakPolarHBondContact O-CB 3.3Å; L121-D124 PolarHBondContact O-N 3.04Å; L121-E125 PolarHBondContact O-N 3.37Å
122	Q	89.7	Confident	85.4	Confident	83 Å²	83	91.2 Å²	91.2	39%	0.388	46%	0.456	S	S	.	.	H	α-helix	trans	-64.9	-34.5	178.5	-170.4	60.1	74.3	0	0	112.8	Y118 Q119 V120 E125	Y118-Q122 PolarHBondContact O-N 3.24Å; Q119-Q122 PolarHBondContact O-N 2.84Å; V120-Q122 VanDerWaalsContact C-N 3.35Å; V120-Q122 PolarHBondContact O-N 3.37Å; Q122-E125 PolarHBondContact NE2-OE2 3.48Å
123	S	85.3	Confident	84.6	Confident	64 Å²	64	91.5 Å²	91.5	45%	0.448	47%	0.466	S	S	.	.	H	α-helix	trans	-71.8	-33.3	174.4	67.4	0	0	0	0	112.6	Q119 V120 L121 M126 D127	Q119-S123 PolarHBondContact O-N 3.39Å; Q119-S123 PolarHBondContact O-OG 3.27Å; V120-S123 PolarHBondContact O-N 3.38Å; V120-S123 PolarHBondContact O-OG 2.88Å; L121-S123 VanDerWaalsContact C-N 3.3Å; L121-S123 PolarHBondContact O-N 2.94Å; S123-M126 PolarHBondContact O-N 3.28Å; S123-D127 PolarHBondContact O-N 3.49Å
124	D	80.9	Confident	84.2	Confident	63 Å²	63	93.2 Å²	93.2	34%	0.337	49%	0.488	S	S	.	.	H	α-helix	trans	-65.7	-41.5	-179.9	-152.4	73.7	0	0	0	111.7	V120 L121 M126 D127 N128 T131	V120-D124 PolarHBondContact O-N 2.91Å; L121-D124 WeakPolarHBondContact O-CB 3.3Å; L121-D124 PolarHBondContact O-N 3.04Å; D124-M126 PolarHBondContact O-N 3.02Å; D124-M126 VanDerWaalsContact O-N 3.16Å; D124-D127 CarbonylContact O-C 3.37Å; D124-D127 WeakPolarHBondContact O-CA 3.45Å; D124-D127 PolarHBondContact O-N 3.32Å; D124-N128 PolarHBondContact O-N 3.45Å; D124-N128 PolarHBondContact O-OD1 2.96Å; D124-T131 VanDerWaalsContact CG-CG2 3.42Å; D124-T131 WeakPolarHBondContact OD1-CG2 3.46Å
125	E	79.5	Confident	83.8	Confident	117 Å²	117	95 Å²	95	55%	0.547	49%	0.488	S	S	.	.	H	α-helix	trans	-57.2	-31.2	176.4	-70.2	-176.7	153	0	0	112.7	L121 Q122	L121-E125 PolarHBondContact O-N 3.37Å; Q122-E125 PolarHBondContact NE2-OE2 3.48Å
126	M	72.7	Confident	83.4	Confident	144 Å²	144	92.7 Å²	92.7	71%	0.709	48%	0.477	S	S	*	.	H	α-helix	trans	-79.3	-23.9	177.3	-58.6	-61	100.6	0	0	112.2	S123 D124	S123-M126 PolarHBondContact O-N 3.28Å; D124-M126 PolarHBondContact O-N 3.02Å; D124-M126 VanDerWaalsContact O-N 3.16Å
127	D	73.4	Confident	83	Confident	73 Å²	73	93.4 Å²	93.4	39%	0.39	49%	0.486	S	S	.	.			trans	-111	14.6	-172.2	-85.3	-26.7	0	0	0	113.8	S123 D124 K129 M130 T131 R140	S123-D127 PolarHBondContact O-N 3.49Å; D124-D127 CarbonylContact O-C 3.37Å; D124-D127 WeakPolarHBondContact O-CA 3.45Å; D124-D127 PolarHBondContact O-N 3.32Å; D127-K129 PolarHBondContact O-N 2.98Å; D127-M130 PolarHBondContact O-N 2.86Å; D127-T131 HydrophobicContact CB-CG2 4.45Å; D127-R140 IonicContact OD2-CZ 3.38Å; D127-R140 IonicContact OD2-NH1 2.91Å; D127-R140 PolarHBondContact OD2-NH1 3Å
128	N	71.6	Confident	82.7	Confident	100 Å²	100	96.3 Å²	96.3	54%	0.535	50%	0.498	S	S	.	.	H	α-helix	trans	-39.5	-31.1	-173	-96.2	21.2	0	0	0	116.7	D124 T131	D124-N128 PolarHBondContact O-N 3.45Å; D124-N128 PolarHBondContact O-OD1 2.96Å; N128-T131 PolarHBondContact O-OG1 3.27Å
129	K	69.9	Low	82.6	Confident	204 Å²	204	93.4 Å²	93.4	89%	0.887	49%	0.49	S	S	*	.	H	α-helix	trans	-70.8	-34	178.5	-64.8	-177.1	-178.1	177.8	0	112.9	D127	D127-K129 PolarHBondContact O-N 2.98Å
130	M	69.5	Low	82.5	Confident	97 Å²	97	91.8 Å²	91.8	48%	0.478	48%	0.478	S	S	.	.	H	α-helix	trans	-82	-23.3	-176.5	-158.9	71.3	120.3	0	0	112.3	D127 S132 V136	D127-M130 PolarHBondContact O-N 2.86Å; M130-S132 VanDerWaalsContact C-N 3.33Å; M130-S132 PolarHBondContact O-N 3.44Å; M130-V136 HydrophobicContact CG-CG1 3.79Å; M130-V136 HydrophobicContact SD-CG1 4.36Å
131	T	74.3	Confident	82.4	Confident	29 Å²	29	94.5 Å²	94.5	18%	0.178	49%	0.491	C	S	.	.	H	α-helix	trans	-85.3	-11.2	-170.3	64.1	0	0	0	0	112.4	D124 D127 N128 C133	D124-T131 VanDerWaalsContact CG-CG2 3.42Å; D124-T131 WeakPolarHBondContact OD1-CG2 3.46Å; D127-T131 HydrophobicContact CB-CG2 4.45Å; N128-T131 PolarHBondContact O-OG1 3.27Å; T131-C133 PolarHBondContact O-N 2.97Å
132	S	77.6	Confident	82.6	Confident	107 Å²	107	91.1 Å²	91.1	75%	0.748	48%	0.477	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.9	-18.1	173.9	-64.3	0	0	0	0	113.9	M130	M130-S132 VanDerWaalsContact C-N 3.33Å; M130-S132 PolarHBondContact O-N 3.44Å
133	C	79.2	Confident	82.7	Confident	66 Å²	66	95 Å²	95	45%	0.446	49%	0.489	S	S	.	.	S	Bend	trans	-99.4	111.3	175.2	-175.5	0	0	0	0	110.3	T131 Y135 V136 A137	T131-C133 PolarHBondContact O-N 2.97Å; C133-Y135 VanDerWaalsContact C-N 3.27Å; C133-Y135 PolarHBondContact O-N 3.26Å; C133-V136 HydrophobicContact CB-CB 4.22Å; C133-V136 HydrophobicContact CB-CG2 4.1Å; C133-V136 PolarHBondContact O-N 3.37Å; C133-V136 VanDerWaalsContact O-N 3.14Å; C133-A137 PolarHBondContact O-N 3.42Å
134	S	87	Confident	83.1	Confident	103 Å²	103	93.5 Å²	93.5	72%	0.72	48%	0.48	S	S	*	.	H	α-helix	trans	-55	-39.3	-175.3	59	0	0	0	0	113.7	H138	S134-H138 VanDerWaalsContact O-CB 3.31Å; S134-H138 WeakPolarHBondContact O-CB 3.48Å; S134-H138 PolarHBondContact O-N 2.93Å
135	Y	89.9	Confident	83.7	Confident	149 Å²	149	92.7 Å²	92.7	58%	0.584	47%	0.474	S	S	*	.	H	α-helix	trans	-63.4	-49.4	178.4	-178.7	-94	0	0	0	111.6	C133 A137 H138 E139	C133-Y135 VanDerWaalsContact C-N 3.27Å; C133-Y135 PolarHBondContact O-N 3.26Å; Y135-A137 PolarHBondContact O-N 2.96Å; Y135-H138 PolarHBondContact O-N 3.37Å; Y135-E139 HydrophobicContact CD1-CG 4.41Å; Y135-E139 HydrophobicContact CE1-CG 3.9Å; Y135-E139 WeakPolarHBondContact CE1-OE1 3.49Å; Y135-E139 VanDerWaalsContact CE1-OE2 3.3Å; Y135-E139 WeakPolarHBondContact CE1-OE2 3.46Å; Y135-E139 VanDerWaalsContact CZ-OE1 3.26Å; Y135-E139 PolarHBondContact O-N 3.14Å; Y135-E139 PolarHBondContact OH-OE1 2.88Å
136	V	87.6	Confident	84.3	Confident	40 Å²	40	89.6 Å²	89.6	24%	0.242	47%	0.465	C	S	.	.	H	α-helix	trans	-66.5	-40.5	-178.8	179.6	0	0	0	0	111	M130 C133 H138 E139 R140	M130-V136 HydrophobicContact CG-CG1 3.79Å; M130-V136 HydrophobicContact SD-CG1 4.36Å; C133-V136 HydrophobicContact CB-CB 4.22Å; C133-V136 HydrophobicContact CB-CG2 4.1Å; C133-V136 PolarHBondContact O-N 3.37Å; C133-V136 VanDerWaalsContact O-N 3.14Å; V136-H138 VanDerWaalsContact C-N 3.34Å; V136-H138 PolarHBondContact O-N 3.16Å; V136-E139 PolarHBondContact O-N 3.44Å; V136-R140 WeakPolarHBondContact O-CG 3.4Å; V136-R140 PolarHBondContact O-N 3.29Å
137	A	87.1	Confident	85.2	Confident	29 Å²	29	85.6 Å²	85.6	24%	0.24	45%	0.449	C	S	.	.	H	α-helix	trans	-61	-44	174.7	0	0	0	0	0	111.4	C133 Y135 R140 L141	C133-A137 PolarHBondContact O-N 3.42Å; Y135-A137 PolarHBondContact O-N 2.96Å; A137-R140 PolarHBondContact O-N 3.46Å; A137-L141 WeakPolarHBondContact O-CB 3.32Å; A137-L141 PolarHBondContact O-N 3.02Å
138	H	89.5	Confident	86	Confident	124 Å²	124	83.7 Å²	83.7	57%	0.574	44%	0.436	S	S	*	.	H	α-helix	trans	-63.8	-42.3	177.6	-175	-83.1	0	0	0	112.3	S134 Y135 V136 L141 S142	S134-H138 VanDerWaalsContact O-CB 3.31Å; S134-H138 WeakPolarHBondContact O-CB 3.48Å; S134-H138 PolarHBondContact O-N 2.93Å; Y135-H138 PolarHBondContact O-N 3.37Å; V136-H138 VanDerWaalsContact C-N 3.34Å; V136-H138 PolarHBondContact O-N 3.16Å; H138-L141 PolarHBondContact O-N 3.24Å; H138-S142 PolarHBondContact CE1-OG 2.73Å; H138-S142 VanDerWaalsContact CE1-OG 3.27Å; H138-S142 PolarHBondContact ND1-OG 3.14Å; H138-S142 VanDerWaalsContact O-CB 3.25Å; H138-S142 WeakPolarHBondContact O-CB 3.47Å; H138-S142 PolarHBondContact O-N 3.42Å; H138-S142 PolarHBondContact O-OG 2.94Å
139	E	92.6	Very high	86.8	Confident	96 Å²	96	83.1 Å²	83.1	45%	0.449	43%	0.427	S	S	.	.	H	α-helix	trans	-62.2	-45.3	176.2	-74.9	-165.9	139.8	0	0	112.1	Y135 V136 S142 Y143	Y135-E139 HydrophobicContact CD1-CG 4.41Å; Y135-E139 HydrophobicContact CE1-CG 3.9Å; Y135-E139 WeakPolarHBondContact CE1-OE1 3.49Å; Y135-E139 VanDerWaalsContact CE1-OE2 3.3Å; Y135-E139 WeakPolarHBondContact CE1-OE2 3.46Å; Y135-E139 VanDerWaalsContact CZ-OE1 3.26Å; Y135-E139 PolarHBondContact O-N 3.14Å; Y135-E139 PolarHBondContact OH-OE1 2.88Å; V136-E139 PolarHBondContact O-N 3.44Å; E139-S142 PolarHBondContact O-N 2.9Å; E139-Y143 WeakPolarHBondContact O-CB 3.43Å; E139-Y143 PolarHBondContact O-N 3.39Å
140	R	90.6	Very high	87.5	Confident	98 Å²	98	80.9 Å²	80.9	37%	0.37	42%	0.421	S	S	.	.	H	α-helix	trans	-60.8	-47.2	177	-74.7	176.6	165.2	-138.9	-7.9	111.9	D127 V136 A137 Y143 A144	D127-R140 IonicContact OD2-CZ 3.38Å; D127-R140 IonicContact OD2-NH1 2.91Å; D127-R140 PolarHBondContact OD2-NH1 3Å; V136-R140 WeakPolarHBondContact O-CG 3.4Å; V136-R140 PolarHBondContact O-N 3.29Å; A137-R140 PolarHBondContact O-N 3.46Å; R140-Y143 PolarHBondContact O-N 2.95Å; R140-A144 WeakPolarHBondContact O-CB 3.4Å; R140-A144 PolarHBondContact O-N 2.76Å
141	L	92.2	Very high	87.6	Confident	84 Å²	84	83.4 Å²	83.4	44%	0.44	43%	0.432	S	S	.	.	H	α-helix	trans	-64.8	-41	178	-175.2	140	0	0	0	111.5	V120 A137 H138 Y143 A144 F145	V120-L141 HydrophobicContact CG1-CD1 4.43Å; A137-L141 WeakPolarHBondContact O-CB 3.32Å; A137-L141 PolarHBondContact O-N 3.02Å; H138-L141 PolarHBondContact O-N 3.24Å; L141-Y143 VanDerWaalsContact C-N 3.32Å; L141-Y143 PolarHBondContact O-N 3.02Å; L141-A144 PolarHBondContact O-N 3.29Å; L141-F145 WeakPolarHBondContact O-CB 3.32Å; L141-F145 PolarHBondContact O-N 3.22Å
142	S	93.4	Very high	86.8	Confident	43 Å²	43	83.6 Å²	83.6	30%	0.301	44%	0.439	S	S	.	.	H	α-helix	trans	-61.9	-40.3	175.9	-62.6	0	0	0	0	112	H138 E139 S146	H138-S142 PolarHBondContact CE1-OG 2.73Å; H138-S142 VanDerWaalsContact CE1-OG 3.27Å; H138-S142 PolarHBondContact ND1-OG 3.14Å; H138-S142 VanDerWaalsContact O-CB 3.25Å; H138-S142 WeakPolarHBondContact O-CB 3.47Å; H138-S142 PolarHBondContact O-N 3.42Å; H138-S142 PolarHBondContact O-OG 2.94Å; E139-S142 PolarHBondContact O-N 2.9Å; S142-S146 WeakPolarHBondContact O-CB 3.46Å; S142-S146 PolarHBondContact O-N 2.98Å; S142-S146 PolarHBondContact O-OG 3.22Å
143	Y	93.7	Very high	85.6	Confident	166 Å²	166	81.5 Å²	81.5	65%	0.651	43%	0.429	S	S	*	.	H	α-helix	trans	-66.6	-53.2	175.2	176.4	-100.5	0	0	0	111.6	E139 R140 L141 F145 S146 V147	E139-Y143 WeakPolarHBondContact O-CB 3.43Å; E139-Y143 PolarHBondContact O-N 3.39Å; R140-Y143 PolarHBondContact O-N 2.95Å; L141-Y143 VanDerWaalsContact C-N 3.32Å; L141-Y143 PolarHBondContact O-N 3.02Å; Y143-F145 PolarHBondContact O-N 3.11Å; Y143-S146 WeakPolarHBondContact O-CA 3.48Å; Y143-S146 WeakPolarHBondContact O-CB 3.44Å; Y143-S146 PolarHBondContact O-N 2.76Å; Y143-V147 HydrophobicContact CD1-CG2 4.28Å; Y143-V147 HydrophobicContact CD2-CG2 4.42Å; Y143-V147 HydrophobicContact CE1-CG2 3.82Å; Y143-V147 HydrophobicContact CE2-CG2 3.97Å; Y143-V147 WeakPolarHBondContact O-CG2 3.22Å; Y143-V147 PolarHBondContact O-N 2.62Å
144	A	93.1	Very high	84.6	Confident	32 Å²	32	82.4 Å²	82.4	26%	0.264	42%	0.423	S	S	.	.	H	α-helix	trans	-56	-42.5	178.6	0	0	0	0	0	111.4	F116 R140 L141 V147 W148	F116-A144 HydrophobicContact CE2-CB 4.18Å; F116-A144 HydrophobicContact CZ-CB 4.3Å; R140-A144 WeakPolarHBondContact O-CB 3.4Å; R140-A144 PolarHBondContact O-N 2.76Å; L141-A144 PolarHBondContact O-N 3.29Å; A144-V147 PolarHBondContact O-N 3.3Å; A144-W148 WeakPolarHBondContact O-CB 3.32Å; A144-W148 PolarHBondContact O-N 3.28Å
145	F	93.1	Very high	83.2	Confident	45 Å²	45	82.3 Å²	82.3	20%	0.197	42%	0.422	C	S	.	.	H	α-helix	trans	-66	-37.6	176.3	178.9	-108.1	0	0	0	112.9	P94 F116 L141 Y143 W148 R149	P94-F145 HydrophobicContact CB-CE2 3.55Å; P94-F145 HydrophobicContact CB-CZ 3.57Å; P94-F145 HydrophobicContact CG-CE2 3.82Å; P94-F145 HydrophobicContact CG-CZ 4.3Å; F116-F145 HydrophobicContact CE1-CB 4.43Å; F116-F145 HydrophobicContact CE1-CD2 4.06Å; F116-F145 HydrophobicContact CZ-CB 3.96Å; F116-F145 HydrophobicContact CZ-CD2 4.3Å; L141-F145 WeakPolarHBondContact O-CB 3.32Å; L141-F145 PolarHBondContact O-N 3.22Å; Y143-F145 PolarHBondContact O-N 3.11Å; F145-W148 HydrophobicContact CD2-CE3 4.1Å; F145-W148 AromaticContact CE2-CE3 3.88Å; F145-W148 HydrophobicContact CE2-CE3 3.88Å; F145-W148 AromaticContact CE2-CZ3 3.94Å; F145-W148 HydrophobicContact CE2-CZ3 3.94Å; F145-R149 HydrophobicContact CE1-CG 4.32Å; F145-R149 HydrophobicContact CE2-CG 4.18Å; F145-R149 HydrophobicContact CZ-CG 3.87Å; F145-R149 VanDerWaalsContact CZ-NE 3.34Å; F145-R149 WeakPolarHBondContact O-CB 3.36Å; F145-R149 PolarHBondContact O-N 3.45Å
146	S	92.6	Very high	81.2	Confident	52 Å²	52	82.4 Å²	82.4	36%	0.364	43%	0.429	S	S	.	.	H	α-helix	trans	-66.6	-42.5	175.7	-62	0	0	0	0	111.7	S142 Y143 R149 M150	S142-S146 WeakPolarHBondContact O-CB 3.46Å; S142-S146 PolarHBondContact O-N 2.98Å; S142-S146 PolarHBondContact O-OG 3.22Å; Y143-S146 WeakPolarHBondContact O-CA 3.48Å; Y143-S146 WeakPolarHBondContact O-CB 3.44Å; Y143-S146 PolarHBondContact O-N 2.76Å; S146-R149 PolarHBondContact O-N 3.12Å; S146-M150 VanDerWaalsContact O-CG 3.3Å; S146-M150 WeakPolarHBondContact O-CG 3.46Å; S146-M150 PolarHBondContact O-N 3.06Å
147	V	90.6	Very high	79.5	Confident	60 Å²	60	84.4 Å²	84.4	36%	0.364	45%	0.445	S	S	.	.	H	α-helix	trans	-62.2	-49.7	174.4	175.7	0	0	0	0	110.4	Y143 A144 R149 M150 E151	Y143-V147 HydrophobicContact CD1-CG2 4.28Å; Y143-V147 HydrophobicContact CD2-CG2 4.42Å; Y143-V147 HydrophobicContact CE1-CG2 3.82Å; Y143-V147 HydrophobicContact CE2-CG2 3.97Å; Y143-V147 WeakPolarHBondContact O-CG2 3.22Å; Y143-V147 PolarHBondContact O-N 2.62Å; A144-V147 PolarHBondContact O-N 3.3Å; V147-R149 VanDerWaalsContact C-N 3.25Å; V147-R149 PolarHBondContact O-N 3.16Å; V147-M150 PolarHBondContact O-N 3.21Å; V147-E151 PolarHBondContact O-N 3.11Å
148	W	90.9	Very high	77.8	Confident	34 Å²	34	88.3 Å²	88.3	13%	0.129	48%	0.477	C	S	.	.	H	α-helix	trans	-57.2	-38.6	177.7	178.6	80.2	0	0	0	112.6	P94 R112 Y113 F116 A144 F145 W154	P94-W148 HydrophobicContact CG-CH2 4.04Å; P94-W148 HydrophobicContact CG-CZ3 3.79Å; R112-W148 HydrophobicContact CB-CZ2 4Å; Y113-W148 HydrophobicContact CD2-CH2 4.32Å; F116-W148 HydrophobicContact CB-CD2 4.24Å; F116-W148 HydrophobicContact CB-CG 4.15Å; F116-W148 HydrophobicContact CB-CZ2 4.44Å; F116-W148 HydrophobicContact CD2-CB 3.61Å; F116-W148 AromaticContact CD2-CD1 3.49Å; F116-W148 VanDerWaalsContact CD2-CD1 3.49Å; F116-W148 HydrophobicContact CD2-CD2 4.17Å; F116-W148 AromaticContact CD2-CG 3.46Å; F116-W148 HydrophobicContact CD2-CG 3.46Å; F116-W148 VanDerWaalsContact CD2-CG 3.46Å; F116-W148 HydrophobicContact CE2-CB 3.64Å; F116-W148 AromaticContact CE2-CG 3.99Å; F116-W148 HydrophobicContact CE2-CG 3.99Å; F116-W148 HydrophobicContact CG-CB 4.37Å; F116-W148 AromaticContact CG-CD1 3.79Å; F116-W148 HydrophobicContact CG-CD2 4.05Å; F116-W148 AromaticContact CG-CG 3.81Å; F116-W148 HydrophobicContact CG-CG 3.81Å; F116-W148 AromaticContact CG-NE1 3.99Å; F116-W148 HydrophobicContact CZ-CB 4.43Å; A144-W148 WeakPolarHBondContact O-CB 3.32Å; A144-W148 PolarHBondContact O-N 3.28Å; F145-W148 HydrophobicContact CD2-CE3 4.1Å; F145-W148 AromaticContact CE2-CE3 3.88Å; F145-W148 HydrophobicContact CE2-CE3 3.88Å; F145-W148 AromaticContact CE2-CZ3 3.94Å; F145-W148 HydrophobicContact CE2-CZ3 3.94Å; W148-W154 PolarHBondContact O-NE1 3.02Å
149	R	88	Confident	75.7	Confident	88 Å²	88	87.8 Å²	87.8	33%	0.332	49%	0.488	S	S	.	.	H	α-helix	trans	-67.1	-44.7	172.1	-88.8	-158.4	-68.6	118.6	0	112.1	F145 S146 V147 E151 W154	F145-R149 HydrophobicContact CE1-CG 4.32Å; F145-R149 HydrophobicContact CE2-CG 4.18Å; F145-R149 HydrophobicContact CZ-CG 3.87Å; F145-R149 VanDerWaalsContact CZ-NE 3.34Å; F145-R149 WeakPolarHBondContact O-CB 3.36Å; F145-R149 PolarHBondContact O-N 3.45Å; S146-R149 PolarHBondContact O-N 3.12Å; V147-R149 VanDerWaalsContact C-N 3.25Å; V147-R149 PolarHBondContact O-N 3.16Å; R149-E151 VanDerWaalsContact C-N 3.32Å; R149-E151 PolarHBondContact O-N 3.34Å; R149-W154 VanDerWaalsContact CA-CZ2 3.47Å; R149-W154 HydrophobicContact CB-CH2 4.41Å; R149-W154 HydrophobicContact CB-CZ2 3.61Å; R149-W154 HydrophobicContact CG-CH2 4.08Å; R149-W154 HydrophobicContact CG-CZ2 3.57Å; R149-W154 WeakPolarHBondContact O-CZ2 3.45Å; R149-W154 PolarHBondContact O-NE1 3.23Å
150	M	84.2	Confident	73.2	Confident	156 Å²	156	95.2 Å²	95.2	77%	0.768	52%	0.522	S	S	*	.	H	α-helix	trans	-71.9	-23.7	-176.4	-70.6	-60.6	-64.3	0	0	114.1	S146 V147 G152	S146-M150 VanDerWaalsContact O-CG 3.3Å; S146-M150 WeakPolarHBondContact O-CG 3.46Å; S146-M150 PolarHBondContact O-N 3.06Å; V147-M150 PolarHBondContact O-N 3.21Å; M150-G152 PolarHBondContact O-N 3.28Å
151	E	71.5	Confident	72.4	Confident	151 Å²	151	95.1 Å²	95.1	71%	0.706	53%	0.529	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.9	3.7	-175.5	-155	166.5	-166.6	0	0	114.5	V147 R149 A153	V147-E151 PolarHBondContact O-N 3.11Å; R149-E151 VanDerWaalsContact C-N 3.32Å; R149-E151 PolarHBondContact O-N 3.34Å; E151-A153 PolarHBondContact O-N 3.45Å
152	G	58.1	Low	71.3	Confident	32 Å²	32	95.6 Å²	95.6	33%	0.33	53%	0.534	S	S	.	.			trans	74	-8.6	151.1	0	0	0	0	0	116.4	M150 W154 S155	M150-G152 PolarHBondContact O-N 3.28Å; G152-W154 PolarHBondContact O-N 2.88Å; G152-S155 PolarHBondContact O-N 3.44Å
153	A	52.9	Low	70.1	Confident	64 Å²	64	98.6 Å²	98.6	53%	0.529	55%	0.547	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66.3	-11.6	-179	0	0	0	0	0	113.6	R112 E151	R112-A153 PolarHBondContact NH1-O 3.48Å; E151-A153 PolarHBondContact O-N 3.45Å
154	W	58.4	Low	68.7	Low	85 Å²	85	94.6 Å²	94.6	32%	0.322	54%	0.541	S	S	.	.	T	Hydrogen-bonded Turn	trans	-94.9	-20.8	-178.7	38.4	-67.8	0	0	0	114.7	L109 R112 W148 R149 G152 M156	L109-W154 HydrophobicContact CD2-CB 3.72Å; L109-W154 HydrophobicContact CD2-CD2 4.39Å; L109-W154 HydrophobicContact CD2-CE3 4.33Å; L109-W154 HydrophobicContact CD2-CG 4.2Å; R112-W154 VanDerWaalsContact CZ-CB 3.5Å; R112-W154 VanDerWaalsContact NH1-CB 3.32Å; R112-W154 VanDerWaalsContact NH1-N 3.15Å; W148-W154 PolarHBondContact O-NE1 3.02Å; R149-W154 VanDerWaalsContact CA-CZ2 3.47Å; R149-W154 HydrophobicContact CB-CH2 4.41Å; R149-W154 HydrophobicContact CB-CZ2 3.61Å; R149-W154 HydrophobicContact CG-CH2 4.08Å; R149-W154 HydrophobicContact CG-CZ2 3.57Å; R149-W154 WeakPolarHBondContact O-CZ2 3.45Å; R149-W154 PolarHBondContact O-NE1 3.23Å; G152-W154 PolarHBondContact O-N 2.88Å; W154-M156 VanDerWaalsContact C-N 3.32Å
155	S	56.8	Low	67.2	Low	100 Å²	100	98.5 Å²	98.5	70%	0.699	56%	0.558	S	S	*	*	T	Hydrogen-bonded Turn	trans	-75.2	-25	172.7	-173	0	0	0	0	112	G152 S157	G152-S155 PolarHBondContact O-N 3.44Å; S155-S157 PolarHBondContact O-N 3.04Å
156	M	47.9	Very low	65.5	Low	151 Å²	151	102.1 Å²	102.1	74%	0.744	58%	0.582	S	S	*	*			trans	-81.4	89.7	-175.8	-60.2	-99.5	102.1	0	0	111.4	W154	W154-M156 VanDerWaalsContact C-N 3.32Å
157	S	53.3	Low	63.5	Low	82 Å²	82	105.6 Å²	105.6	57%	0.573	60%	0.598	S	S	*	*			trans	163.5	67.6	132	69.4	0	0	0	0	111	S155 S159	S155-S157 PolarHBondContact O-N 3.04Å; S157-S159 PolarHBondContact O-N 3.27Å
158	A	50.5	Low	61.5	Low	111 Å²	111	109.2 Å²	109.2	92%	0.917	62%	0.616	S	S	*	*			trans	-83.5	68.2	145.6	0	0	0	0	0	107.2
159	S	45.9	Very low	59	Low	114 Å²	114	115.4 Å²	115.4	80%	0.797	66%	0.657	S	S	*	*			trans	-115.8	94.6	160.9	-160.2	0	0	0	0	104.6	S157	S157-S159 PolarHBondContact O-N 3.27Å
160	H	40.8	Very low	56.4	Low	251 Å²	251	117.9 Å²	117.9	100%	1.162	69%	0.686	S	S	*	*			trans	-100.2	0	167.9	-149.3	-57	0	0	0	108.3

Retrieved 160 of 160 residues in 58.5 ms (Link to these results)

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