CEP41_MOUSE Loading...

Isoform 2 of Centrosomal protein of 41 kDa AlphaSync

Canonical isoform description: Required during ciliogenesis for tubulin glutamylation in cilium. Probably acts by participating in the transport of TTLL6, a tubulin polyglutamylase, between the basal body and the cilium.

AlphaFold DB , UniProt , Accession Q99NF3-2 (canonical: Q99NF3), Species MOUSE (Mus musculus, Mouse), Gene Cep41, Length 43 aa.

						>CEP41_MOUSE|Q99NF3-2|Cep41
MSARRHIGNPEYLTRRIPQNPRYQHVKSRLDTACASQLRVFGI
					

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(Predicted Aligned Error values between residue pairs)

Download Structure AlphaSync Parameters PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	46.6	Very low	63.5	Low	240 Å²	240	139 Å²	139	100%	1.182	72%	0.723	S	S	*	*				0	101.4	0	-64.6	179.4	79	0	0	108.3
2	S	57.8	Low	63.7	Low	128 Å²	128	140.3 Å²	140.3	90%	0.895	71%	0.713	S	S	*	*			trans	-124.9	113.7	159.4	-84.2	0	0	0	0	106.6
3	A	61.5	Low	64.3	Low	97 Å²	97	139 Å²	139	80%	0.802	71%	0.708	S	S	*	*			trans	-54.7	137.8	-169.7	0	0	0	0	0	111	R5	A3-R5 PolarHBondContact O-N 3.33Å
4	R	62.9	Low	64.8	Low	237 Å²	237	137.3 Å²	137.3	89%	0.894	71%	0.708	S	S	*	*			trans	13.4	101.5	153.2	-72.8	175.1	164.4	98.6	-0.9	113.3	H6	R4-H6 PolarHBondContact O-N 3.08Å
5	R	63.1	Low	65.2	Low	239 Å²	239	137.7 Å²	137.7	90%	0.902	70%	0.697	S	S	*	*			trans	-46.2	108.6	162	-53.1	-179.5	80.7	-158.4	4.7	106	A3 I7	A3-R5 PolarHBondContact O-N 3.33Å; R5-I7 PolarHBondContact O-N 2.87Å; R5-I7 VanDerWaalsContact O-N 3.08Å
6	H	64.2	Low	65.8	Low	131 Å²	131	141.9 Å²	141.9	61%	0.606	70%	0.702	S	S	*	*			trans	-53.2	120.8	-175.7	-172.5	-86.6	0	0	0	107.3	R4 G8	R4-H6 PolarHBondContact O-N 3.08Å; H6-G8 PolarHBondContact ND1-O 2.96Å; H6-G8 PolarHBondContact O-N 2.83Å
7	I	67.5	Low	66.2	Low	167 Å²	167	138.5 Å²	138.5	86%	0.856	69%	0.686	S	S	*	*	S	Bend	trans	-65.7	105.8	-177.5	-67.8	156.7	0	0	0	106	R5	R5-I7 PolarHBondContact O-N 2.87Å; R5-I7 VanDerWaalsContact O-N 3.08Å
8	G	65.2	Low	66.8	Low	52 Å²	52	137.3 Å²	137.3	54%	0.536	69%	0.69	S	S	.	*	S	Bend	trans	79.6	149	178.9	0	0	0	0	0	114.3	H6	H6-G8 PolarHBondContact ND1-O 2.96Å; H6-G8 PolarHBondContact O-N 2.83Å
9	N	68.9	Low	67.3	Low	66 Å²	66	137.7 Å²	137.7	35%	0.353	69%	0.689	S	S	.	*			trans	-65	121.4	172.1	177.6	-3.5	0	0	0	108.7	E11 Y12	N9-E11 PolarHBondContact ND2-OE2 3.07Å; N9-E11 PolarHBondContact O-N 3.5Å; N9-E11 VanDerWaalsContact OD1-CB 3.25Å; N9-E11 WeakPolarHBondContact OD1-CB 3.2Å; N9-E11 WeakPolarHBondContact OD1-CG 3.25Å; N9-E11 PolarHBondContact OD1-N 3.06Å; N9-Y12 HydrophobicContact CB-CD2 3.89Å; N9-Y12 HydrophobicContact CB-CE2 3.96Å; N9-Y12 PolarHBondContact O-N 3.14Å; N9-Y12 VanDerWaalsContact O-N 3.14Å
10	P	68.9	Low	67.9	Low	68 Å²	68	135.2 Å²	135.2	44%	0.442	68%	0.678	S	S	.	*	T	Hydrogen-bonded Turn	trans	-59.3	-18.9	179.6	25.6	-35.4	0	0	0	113	Y12 L13 T14	P10-Y12 PolarHBondContact O-N 3.06Å; P10-L13 PolarHBondContact O-N 3Å; P10-T14 PolarHBondContact O-N 3.46Å
11	E	71.4	Confident	68.3	Low	104 Å²	104	133.7 Å²	133.7	49%	0.486	68%	0.678	S	S	.	*	H	α-helix	trans	-57.9	-28.1	174.9	-70.1	172.9	178.9	0	0	113.5	N9 T14 R15	N9-E11 PolarHBondContact ND2-OE2 3.07Å; N9-E11 PolarHBondContact O-N 3.5Å; N9-E11 VanDerWaalsContact OD1-CB 3.25Å; N9-E11 WeakPolarHBondContact OD1-CB 3.2Å; N9-E11 WeakPolarHBondContact OD1-CG 3.25Å; N9-E11 PolarHBondContact OD1-N 3.06Å; E11-T14 PolarHBondContact O-OG1 2.84Å; E11-T14 VanDerWaalsContact O-OG1 3.12Å; E11-R15 VanDerWaalsContact O-CG 3.25Å; E11-R15 WeakPolarHBondContact O-CG 3.25Å; E11-R15 PolarHBondContact O-N 3.19Å
12	Y	67	Low	69.9	Low	154 Å²	154	130.7 Å²	130.7	60%	0.604	65%	0.653	S	S	*	*	H	α-helix	trans	-76.2	-29	177.4	-67.1	-73	0	0	0	112.5	N9 P10	N9-Y12 HydrophobicContact CB-CD2 3.89Å; N9-Y12 HydrophobicContact CB-CE2 3.96Å; N9-Y12 PolarHBondContact O-N 3.14Å; N9-Y12 VanDerWaalsContact O-N 3.14Å; P10-Y12 PolarHBondContact O-N 3.06Å
13	L	70.3	Confident	70.9	Confident	124 Å²	124	130.3 Å²	130.3	65%	0.649	63%	0.633	S	S	*	*	H	α-helix	trans	-77.4	-26.1	178.3	-58.8	174.9	0	0	0	111.7	P10	P10-L13 PolarHBondContact O-N 3Å
14	T	72.3	Confident	71.6	Confident	115 Å²	115	132.8 Å²	132.8	71%	0.706	63%	0.628	S	S	*	*	H	α-helix	trans	-85.2	-16.1	176	59.7	0	0	0	0	113.3	P10 E11 R16	P10-T14 PolarHBondContact O-N 3.46Å; E11-T14 PolarHBondContact O-OG1 2.84Å; E11-T14 VanDerWaalsContact O-OG1 3.12Å; T14-R16 PolarHBondContact O-N 3.21Å
15	R	70.6	Confident	72.4	Confident	144 Å²	144	128.7 Å²	128.7	54%	0.543	62%	0.619	S	S	.	*	S	Bend	trans	-67.7	120.4	176.7	-79	169.8	-162.1	-161.4	4.7	109.7	E11 I17	E11-R15 VanDerWaalsContact O-CG 3.25Å; E11-R15 WeakPolarHBondContact O-CG 3.25Å; E11-R15 PolarHBondContact O-N 3.19Å; R15-I17 PolarHBondContact O-N 3.25Å
16	R	73.9	Confident	73	Confident	204 Å²	204	121.7 Å²	121.7	77%	0.77	60%	0.602	S	S	*	*	P	Polyproline II helix	trans	-56.5	120.9	172.8	-177.7	173.5	174.5	148.2	-3.1	109.2	T14	T14-R16 PolarHBondContact O-N 3.21Å
17	I	74	Confident	73.3	Confident	85 Å²	85	123.8 Å²	123.8	44%	0.436	61%	0.61	S	S	.	*	P	Polyproline II helix	trans	-62.2	128.5	178.8	-62.1	162.9	0	0	0	108.4	R15 Q19 F41	R15-I17 PolarHBondContact O-N 3.25Å; I17-Q19 PolarHBondContact O-N 3.37Å; I17-Q19 VanDerWaalsContact O-N 3.16Å; I17-F41 HydrophobicContact CG2-CZ 3.6Å; I17-F41 HydrophobicContact CG2-CE1 3.32Å; I17-F41 HydrophobicContact CG2-CD1 4.42Å; I17-F41 HydrophobicContact CG1-CE1 3.97Å; I17-F41 HydrophobicContact CG1-CD1 4.33Å; I17-F41 HydrophobicContact CD1-CZ 4.08Å; I17-F41 HydrophobicContact CD1-CE1 3.26Å; I17-F41 HydrophobicContact CD1-CG 4.11Å; I17-F41 HydrophobicContact CB-CD1 4.28Å; I17-F41 HydrophobicContact CB-CE1 3.55Å; I17-F41 HydrophobicContact CD1-CD1 3.25Å; I17-F41 HydrophobicContact CB-CZ 4.33Å
18	P	75.8	Confident	73.4	Confident	117 Å²	117	119.5 Å²	119.5	76%	0.76	60%	0.595	S	S	*	*	P	Polyproline II helix	trans	-59.7	122.4	-179.2	23.5	-34	0	0	0	109.7	N20	P18-N20 PolarHBondContact O-N 3.12Å
19	Q	76.8	Confident	73.6	Confident	145 Å²	145	128.2 Å²	128.2	68%	0.678	61%	0.611	S	S	*	*	P	Polyproline II helix	trans	-72.9	123.8	169.1	-69.9	-177.8	-25.2	0	0	107.5	I17 P21	I17-Q19 PolarHBondContact O-N 3.37Å; I17-Q19 VanDerWaalsContact O-N 3.16Å; Q19-P21 VanDerWaalsContact O-CD 3.31Å; Q19-P21 WeakPolarHBondContact O-CD 3.31Å
20	N	78.4	Confident	73.7	Confident	87 Å²	87	131 Å²	131	47%	0.465	63%	0.626	S	S	.	*			trans	-70.6	115.6	-179.7	-171.1	-25	0	0	0	109.4	P18 R22 Y23 Q24	P18-N20 PolarHBondContact O-N 3.12Å; N20-R22 WeakPolarHBondContact OD1-CB 3.49Å; N20-R22 VanDerWaalsContact OD1-N 3.11Å; N20-R22 PolarHBondContact OD1-N 3.17Å; N20-R22 VanDerWaalsContact OD1-CB 3.26Å; N20-R22 VanDerWaalsContact O-N 3.15Å; N20-R22 PolarHBondContact O-N 3.11Å; N20-Y23 HydrophobicContact CB-CD2 3.96Å; N20-Y23 WeakPolarHBondContact ND2-CE2 3.26Å; N20-Y23 PolarHBondContact O-N 3.35Å; N20-Q24 PolarHBondContact O-N 3.29Å
21	P	77.7	Confident	73.4	Confident	103 Å²	103	135.6 Å²	135.6	67%	0.669	65%	0.647	S	S	*	*	G	3₁₀ helix	trans	-60.8	-28.5	-176.7	24.3	-34	0	0	0	112.2	Q19 Y23 Q24	Q19-P21 VanDerWaalsContact O-CD 3.31Å; Q19-P21 WeakPolarHBondContact O-CD 3.31Å; P21-Y23 PolarHBondContact O-N 3.26Å; P21-Q24 PolarHBondContact O-N 3.19Å
22	R	80.6	Confident	72.9	Confident	178 Å²	178	136 Å²	136	67%	0.672	66%	0.656	S	S	*	*	G	3₁₀ helix	trans	-60.5	-27.6	177.4	-172.4	177.7	173.7	-167.7	-2.9	113	N20 H25	N20-R22 WeakPolarHBondContact OD1-CB 3.49Å; N20-R22 VanDerWaalsContact OD1-N 3.11Å; N20-R22 PolarHBondContact OD1-N 3.17Å; N20-R22 VanDerWaalsContact OD1-CB 3.26Å; N20-R22 VanDerWaalsContact O-N 3.15Å; N20-R22 PolarHBondContact O-N 3.11Å; R22-H25 PolarHBondContact O-CE1 2.87Å
23	Y	77.1	Confident	72.3	Confident	120 Å²	120	133 Å²	133	47%	0.471	66%	0.663	S	S	.	*	G	3₁₀ helix	trans	-114.3	8.4	-175.8	-56.6	-68.2	0	0	0	113.5	N20 P21 H25 V26	N20-Y23 HydrophobicContact CB-CD2 3.96Å; N20-Y23 WeakPolarHBondContact ND2-CE2 3.26Å; N20-Y23 PolarHBondContact O-N 3.35Å; P21-Y23 PolarHBondContact O-N 3.26Å; Y23-H25 PolarHBondContact O-N 3.42Å; Y23-H25 VanDerWaalsContact O-N 3.15Å; Y23-V26 HydrophobicContact CD1-CG2 4.5Å; Y23-V26 PolarHBondContact O-N 3.16Å
24	Q	76.8	Confident	71.4	Confident	148 Å²	148	132.8 Å²	132.8	69%	0.692	67%	0.671	S	S	*	*	T	Hydrogen-bonded Turn	trans	-57.6	-32.2	-178.5	-174.3	178.4	12.6	0	0	113.3	N20 P21	N20-Q24 PolarHBondContact O-N 3.29Å; P21-Q24 PolarHBondContact O-N 3.19Å
25	H	79.1	Confident	70.7	Confident	151 Å²	151	130.2 Å²	130.2	70%	0.699	66%	0.661	S	S	*	*	T	Hydrogen-bonded Turn	trans	-85.3	-12.7	179.1	56.8	-91.3	0	0	0	113.2	R22 Y23 K27	R22-H25 PolarHBondContact O-CE1 2.87Å; Y23-H25 PolarHBondContact O-N 3.42Å; Y23-H25 VanDerWaalsContact O-N 3.15Å; H25-K27 PolarHBondContact O-N 3.28Å
26	V	76.6	Confident	69.7	Low	92 Å²	92	127.7 Å²	127.7	56%	0.558	67%	0.665	S	S	*	*			trans	-92.2	86.3	179.9	-173.7	0	0	0	0	108.6	Y23	Y23-V26 HydrophobicContact CD1-CG2 4.5Å; Y23-V26 PolarHBondContact O-N 3.16Å
27	K	69.5	Low	68.8	Low	175 Å²	175	123.7 Å²	123.7	76%	0.761	66%	0.656	S	S	*	*			trans	-82.5	139.9	168.3	-63	-178.9	-176.3	178	0	108.9	H25 R29	H25-K27 PolarHBondContact O-N 3.28Å; K27-R29 PolarHBondContact O-N 2.97Å
28	S	69.6	Low	67.8	Low	77 Å²	77	126.8 Å²	126.8	54%	0.538	67%	0.672	S	S	.	*			trans	-61.2	121.4	170.2	46.2	0	0	0	0	108.4	L30	S28-L30 PolarHBondContact O-N 3.15Å
29	R	70.8	Confident	66.7	Low	236 Å²	236	130.4 Å²	130.4	89%	0.891	67%	0.671	S	S	*	*			trans	-82.6	15.2	-178.6	-62.9	-176.2	-68.2	152.7	-0.7	113.1	K27 D31	K27-R29 PolarHBondContact O-N 2.97Å; R29-D31 PolarHBondContact O-N 3.42Å
30	L	71.1	Confident	65.6	Low	124 Å²	124	129.1 Å²	129.1	65%	0.649	67%	0.672	S	S	*	*			trans	-88.5	98.3	177.9	-71.5	176.3	0	0	0	107.6	S28 T32	S28-L30 PolarHBondContact O-N 3.15Å; L30-T32 PolarHBondContact O-N 3.15Å
31	D	61.9	Low	64.4	Low	165 Å²	165	131.3 Å²	131.3	88%	0.882	68%	0.678	S	S	*	*			trans	-69.8	33.9	167.6	-70	-32	0	0	0	111.7	R29 A33	R29-D31 PolarHBondContact O-N 3.42Å; D31-A33 PolarHBondContact O-N 3.2Å; D31-A33 VanDerWaalsContact O-N 3.11Å
32	T	60.4	Low	63.1	Low	111 Å²	111	129.2 Å²	129.2	68%	0.681	68%	0.675	S	S	*	*			trans	-73.5	105.7	166.1	-44.5	0	0	0	0	106.3	L30 C34	L30-T32 PolarHBondContact O-N 3.15Å; T32-C34 PolarHBondContact O-N 3.04Å; T32-C34 VanDerWaalsContact O-N 3.07Å
33	A	55.6	Low	61.4	Low	91 Å²	91	130.4 Å²	130.4	75%	0.752	69%	0.693	S	S	*	*			trans	-39.1	119	165.8	0	0	0	0	0	110.6	D31	D31-A33 PolarHBondContact O-N 3.2Å; D31-A33 VanDerWaalsContact O-N 3.11Å
34	C	51.4	Low	60.6	Low	120 Å²	120	131 Å²	131	81%	0.811	70%	0.704	S	S	*	*	S	Bend	trans	77.4	117.3	155	-145.2	0	0	0	0	119.3	T32	T32-C34 PolarHBondContact O-N 3.04Å; T32-C34 VanDerWaalsContact O-N 3.07Å
35	A	56.3	Low	59.7	Low	62 Å²	62	130.1 Å²	130.1	51%	0.512	71%	0.705	S	S	.	*			trans	87.5	9.6	130.1	0	0	0	0	0	123.7
36	S	51.2	Low	58.7	Low	90 Å²	90	128.9 Å²	128.9	63%	0.629	71%	0.705	S	S	*	*	S	Bend	trans	-94.9	-35.6	174.4	60.6	0	0	0	0	115.8
37	Q	53.6	Low	57.6	Low	121 Å²	121	131.1 Å²	131.1	57%	0.565	71%	0.714	S	S	*	*	T	Hydrogen-bonded Turn	trans	-89.5	-24.9	-171.1	-62.2	-173.8	24.3	0	0	114.9	R39	Q37-R39 VanDerWaalsContact C-N 3.35Å
38	L	53.4	Low	56.9	Low	149 Å²	149	128.3 Å²	128.3	78%	0.78	71%	0.711	S	S	*	*	T	Hydrogen-bonded Turn	trans	-81.2	-14.9	171.6	-79.4	170.3	0	0	0	113.1	V40 F41 G42	L38-V40 VanDerWaalsContact C-N 3.33Å; L38-F41 PolarHBondContact O-N 3.11Å; L38-G42 PolarHBondContact O-N 3.37Å
39	R	53.9	Low	56	Low	194 Å²	194	131.7 Å²	131.7	73%	0.732	72%	0.722	S	S	*	*	T	Hydrogen-bonded Turn	trans	-76.8	-21.5	175.2	-161.6	-178.7	-74.2	-131.4	0.5	112.5	Q37 G42	Q37-R39 VanDerWaalsContact C-N 3.35Å; R39-G42 PolarHBondContact O-N 2.99Å
40	V	52.7	Low	55	Low	117 Å²	117	124.3 Å²	124.3	71%	0.709	71%	0.71	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77.3	-15	171.4	-175.6	0	0	0	0	111.8	L38	L38-V40 VanDerWaalsContact C-N 3.33Å
41	F	52.9	Low	53.7	Low	133 Å²	133	124.3 Å²	124.3	58%	0.583	72%	0.715	S	S	*	*	T	Hydrogen-bonded Turn	trans	-100.5	9.8	175.1	-110.5	-115.1	0	0	0	113.1	I17 L38	I17-F41 HydrophobicContact CG2-CZ 3.6Å; I17-F41 HydrophobicContact CG2-CE1 3.32Å; I17-F41 HydrophobicContact CG2-CD1 4.42Å; I17-F41 HydrophobicContact CG1-CE1 3.97Å; I17-F41 HydrophobicContact CG1-CD1 4.33Å; I17-F41 HydrophobicContact CD1-CZ 4.08Å; I17-F41 HydrophobicContact CD1-CE1 3.26Å; I17-F41 HydrophobicContact CD1-CG 4.11Å; I17-F41 HydrophobicContact CB-CD1 4.28Å; I17-F41 HydrophobicContact CB-CE1 3.55Å; I17-F41 HydrophobicContact CD1-CD1 3.25Å; I17-F41 HydrophobicContact CB-CZ 4.33Å; L38-F41 PolarHBondContact O-N 3.11Å
42	G	50	Low	53.1	Low	59 Å²	59	120.9 Å²	120.9	61%	0.608	70%	0.701	S	S	*	*			trans	-122.3	20.2	-170.7	0	0	0	0	0	115.8	L38 R39	L38-G42 PolarHBondContact O-N 3.37Å; R39-G42 PolarHBondContact O-N 2.99Å
43	I	45.5	Very low	52.4	Low	204 Å²	204	121.8 Å²	121.8	100%	1.046	70%	0.703	S	S	*	*			trans	-128.4	0	163.2	53.1	169.4	0	0	0	110.2

Retrieved 43 of 43 residues in 97.5 ms (Link to these results)

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