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Keratin-associated protein 19-9b

In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

AlphaFold DB , UniProt , Accession Q99NG9, Species MOUSE (Mus musculus, Mouse), Gene Krtap19-9b, Length 58 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M40.1Very low55.5Low229 Ų229149.9 Ų149.9100%1.12877%0.767SS**  0126.50-141.782.9160.400107.2
2S47.3Very low55.8Low77 Ų77151.4 Ų151.454%0.53878%0.776SS.*  trans87.684151.7-55.30000120.8
3Y52.3Low55.7Low187 Ų187145.4 Ų145.473%0.73377%0.774SS**  87.3109115.9-52.2-47000120.6
4Y57Low55.9Low207 Ų207150.1 Ų150.181%0.81278%0.778SS**  52.390.4129.1-68.9-89.7000117.9
5Y57.5Low56.1Low201 Ų201143.9 Ų143.979%0.78877%0.765SS**  trans-156.952.1149-128.6-81.7000112.7Y8Y5-Y8 HydrophobicContact CD1-CE2 3.77Å; Y5-Y8 AromaticContact CE1-CE2 3.91Å; Y5-Y8 HydrophobicContact CE1-CE2 3.91Å; Y5-Y8 AromaticContact CD1-CE2 3.77Å
6G60.2Low56.2Low75 Ų75146.8 Ų146.877%0.77378%0.78SS**  trans-115.541.4-179.500000113.4
7N58.7Low56.2Low155 Ų155142.8 Ų142.883%0.82978%0.781SS**  trans-116.980.8172.5-100.6-67.4000108.8
8Y59.8Low55.9Low170 Ų170138.8 Ų138.867%0.66778%0.779SS**  trans-127.410.2178.6-91.5-74.5000114.8Y5Y5-Y8 HydrophobicContact CD1-CE2 3.77Å; Y5-Y8 AromaticContact CE1-CE2 3.91Å; Y5-Y8 HydrophobicContact CE1-CE2 3.91Å; Y5-Y8 AromaticContact CD1-CE2 3.77Å
9Y57.1Low55.7Low223 Ų223142.8 Ų142.888%0.87579%0.787SS**  trans-139.452.2177.3-73.6-82.3000112.2
10G58.1Low55.4Low81 Ų81139.9 Ų139.984%0.83579%0.791SS**  trans-92.9122.3151.300000108.1
11G62.2Low55.1Low44 Ų44136.5 Ų136.545%0.45479%0.788SS.*SBendtrans140.98.5161.900000119.6
12L59.8Low55.6Low168 Ų168136 Ų13688%0.8878%0.779SS**  trans-123.736.7178.7-67.4173.4000113.6
13G54.2Low55.7Low73 Ų73136.1 Ų136.175%0.75379%0.793SS**  trans-94.419.5172.600000114.4
14Y57.8Low55.7Low211 Ų211130.8 Ų130.883%0.82779%0.794SS**  trans-115.347.8-178.6-39.6-79.4000110.5
15G59.4Low55.5Low57 Ų57129.8 Ų129.859%0.58880%0.802SS**SBendtrans-114.197.5178.700000109.8G17G15-G17 PolarHBondContact O-N 2.72Å
16L57.4Low55.3Low191 Ų191123 Ų123100%179%0.794SS**  trans45.334.4131-70.7154.2000117.4
17G55.8Low54.9Low78 Ų78130.7 Ų130.780%0.80480%0.801SS**  trans-116.492.6-178.400000109.9G15G15-G17 PolarHBondContact O-N 2.72Å
18G52Low54.6Low71 Ų71127 Ų12773%0.73280%0.799SS**SBendtrans154.5-14.7166.900000117.4G20G18-G20 PolarHBondContact O-N 3.18Å
19F51.7Low54.1Low216 Ų216130.7 Ų130.795%0.94781%0.814SS**  trans-83.223.8170.3-76.5-83.3000112.8G21F19-G21 PolarHBondContact O-N 3.29Å
20G50.4Low53.9Low83 Ų83123.3 Ų123.386%0.85681%0.805SS**  trans-87.780.5173.600000110.9G18G18-G20 PolarHBondContact O-N 3.18Å
21G47.4Very low53.2Low70 Ų70123.5 Ų123.572%0.72279%0.794SS**  trans-150.36.1176.400000115.3F19 G23F19-G21 PolarHBondContact O-N 3.29Å; G21-G23 VanDerWaalsContact C-N 3.31Å
22F52.3Low52.7Low218 Ų218126.5 Ų126.596%0.95681%0.808SS**  trans-96.236.8173.4-85.6-89.6000111.7
23G47.7Very low52.1Low79 Ų79128.3 Ų128.381%0.81480%0.804SS**  trans-114.4102.1-179.800000111G21G21-G23 VanDerWaalsContact C-N 3.31Å
24G53.8Low51.9Low75 Ų75127.8 Ų127.877%0.77380%0.799SS**  trans167.616174.200000118G26G24-G26 VanDerWaalsContact O-N 3.11Å; G24-G26 PolarHBondContact O-N 3.21Å; G24-G26 VanDerWaalsContact C-N 3.29Å
25L51.5Low51.5Low187 Ų187127 Ų12798%0.97981%0.809SS**  trans-77.685.1161.8-71.3166.7000107.5
26G54.6Low50.9Low59 Ų59127.9 Ų127.961%0.60882%0.817SS**  trans-161.285.1-170.100000114.5G24G24-G26 VanDerWaalsContact O-N 3.11Å; G24-G26 PolarHBondContact O-N 3.21Å; G24-G26 VanDerWaalsContact C-N 3.29Å
27Y51.6Low50.5Low236 Ų236121.8 Ų121.893%0.92580%0.8SS**  trans33.6106.8138-69.1-93000119
28G51.2Low50.2Low76 Ų76129.3 Ų129.378%0.78481%0.806SS**  74.294.9125.700000118.6
29Y50Low49.9Very low249 Ų249129.8 Ų129.898%0.97681%0.811SS**  trans-169.9120.6140-142.7-103000109
30G53.3Low49.6Very low68 Ų68122 Ų12270%0.70179%0.792SS**  trans158.856.4173.500000116.1S32G30-S32 PolarHBondContact O-N 3.1Å; G30-S32 VanDerWaalsContact O-N 3.1Å
31S42.6Very low49.5Very low84 Ų84129.3 Ų129.359%0.58780%0.795SS**  trans-52109.9157.9-89.60000110.7Y33S31-Y33 WeakPolarHBondContact CB-OH 3.19Å; S31-Y33 PolarHBondContact OG-OH 3.11Å
32S53.1Low49.7Very low108 Ų108129 Ų12976%0.75579%0.791SS**  trans-154.274.9159.2-74.40000109.3G30 G34G30-S32 PolarHBondContact O-N 3.1Å; G30-S32 VanDerWaalsContact O-N 3.1Å; S32-G34 PolarHBondContact O-N 3.15Å; S32-G34 VanDerWaalsContact O-N 3.15Å
33Y46.2Very low49.5Very low205 Ų205129.5 Ų129.580%0.80479%0.789SS**  trans-41.8109.1147.78.6-94.8000109.1S31S31-Y33 WeakPolarHBondContact CB-OH 3.19Å; S31-Y33 PolarHBondContact OG-OH 3.11Å
34G51Low49.7Very low63 Ų63135.4 Ų135.465%0.64979%0.792SS**  trans-174.551.3-174.200000112.9S32 G36S32-G34 PolarHBondContact O-N 3.15Å; S32-G34 VanDerWaalsContact O-N 3.15Å; G34-G36 VanDerWaalsContact C-N 3.35Å; G34-G36 PolarHBondContact O-N 2.99Å
35L49.3Very low49.8Very low195 Ų195136.9 Ų136.9100%1.02179%0.791SS**  trans-60.897162-104.4149000108.2
36G46.9Very low49.8Very low74 Ų74133.8 Ų133.876%0.76378%0.782SS**  trans140113.4168.500000113.6G34G34-G36 VanDerWaalsContact C-N 3.35Å; G34-G36 PolarHBondContact O-N 2.99Å
37G49.3Very low49.5Very low63 Ų63135 Ų13565%0.64978%0.781SS**  trans145.8108.8155.500000115.4
38Y49.2Very low49.4Very low237 Ų237132 Ų13293%0.92977%0.773SS**  trans66101.4142.5-67.4-90.9000119.3
39G44.5Very low49.4Very low80 Ų80139.8 Ų139.883%0.82578%0.78SS**  77.1119113.200000118.7
40G45.7Very low49.4Very low53 Ų53131.6 Ų131.655%0.54677%0.772SS.*  trans152.5145.3155.700000112.4
41Y48.5Very low49.1Very low237 Ų237131.6 Ų131.693%0.92977%0.772SS**  trans76.995.3168.1-26.5-67.4000113.9
42G52.5Low49.4Very low62 Ų62135.9 Ų135.964%0.63978%0.776SS**  cis91.198.730.800000111
43Y47.9Very low49.4Very low230 Ų230139 Ų13990%0.90278%0.784SS**  trans7395.5158.5-56.1-90000119.3
44F50.5Low49.4Very low203 Ų203134.9 Ų134.989%0.8979%0.785SS**  167.5105112.6-135.9-102.1000109.7
45S57.4Low49.4Very low106 Ų106137 Ų13774%0.74179%0.79SS**  trans-86139.6166.2-69.80000109.8
46P51.3Low49.4Very low121 Ų121131.2 Ų131.279%0.78678%0.777SS**  trans-100.7115.4130.428.3-17.5000107.4
47S48Very low49.6Very low86 Ų86137.3 Ų137.360%0.60178%0.783SS**  trans-43.9164.2162.6-49.30000111.4
48F49.9Very low49.5Very low173 Ų173149.1 Ų149.176%0.75981%0.81SS**  trans86.276.6-177.6-50.8-79000114.1
49Y50.7Low49.5Very low238 Ų238144.8 Ų144.893%0.93380%0.804SS**SBendtrans-171.92.1131.5-121.8-91.1000116.9
50G49.6Very low49.8Very low78 Ų78148.2 Ų148.280%0.80480%0.803SS**SBendtrans-160.2114.217700000113.2
51G47.6Very low50Low67 Ų67153.4 Ų153.469%0.69182%0.817SS**  trans136.747.1159.700000118.1
52Y49Very low50.1Low175 Ų175148.5 Ų148.569%0.68681%0.811SS**  trans-16683.4159.428.6-99.4000112
53L51.8Low49.9Very low174 Ų174153.9 Ų153.991%0.91182%0.821SS**  trans-146.3110.7142.3-82.2-177.8000108.9
54S46.8Very low50Low118 Ų118148.9 Ų148.983%0.82582%0.816SS**  trans-16.5128.3160.8-60.30000116.5
55S50.2Low50Low108 Ų108145 Ų14576%0.75581%0.811SS**  -170.976.6128.441.40000108.8F57S55-F57 VanDerWaalsContact C-N 3.35Å; S55-F57 PolarHBondContact O-N 3.21Å
56G49.6Very low49.4Very low73 Ų73148 Ų14875%0.75382%0.816SS**  trans-74.196.1154.700000107.9
57F52.3Low49.3Very low201 Ų201150.3 Ų150.388%0.88282%0.819SS**  trans-146114.5157.4-77.6-76.4000107.5S55S55-F57 VanDerWaalsContact C-N 3.35Å; S55-F57 PolarHBondContact O-N 3.21Å
58Y46.1Very low49.4Very low312 Ų312156.1 Ų156.1100%1.22484%0.838SS**  trans-63.40157.6-105.9-95.9000109.9

Retrieved 58 of 58 residues in 41.5 ms (Link to these results)