Q99NV7_RAT Loading...

Brain-derived neurotrophic factor

During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. Important signaling molecule that activates signaling cascades downstream of NTRK2. Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2. Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD). Binding to NGFR and SORCS2 promotes neuronal apoptosis. Promotes neuronal growth cone collapse. Important signaling molecule that activates signaling cascades downstream of NTRK2. During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.

AlphaFold DB , UniProt , Accession Q99NV7, Species RAT (Rattus norvegicus, Rat), Gene Bdnf, Length 188 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	Y	33.1	Very low	42.2	Very low	284 Å²	284	159.4 Å²	159.4	100%	1.114	85%	0.849	S	S	*	*				0	95.6	0	-97.4	-93.9	0	0	0	108.4
2	F	37.7	Very low	42.3	Very low	218 Å²	218	162.3 Å²	162.3	96%	0.956	85%	0.854	S	S	*	*			trans	-127.8	95.9	170	-79.3	-79.6	0	0	0	106.6
3	G	38.7	Very low	41.9	Very low	64 Å²	64	157.7 Å²	157.7	66%	0.66	85%	0.853	S	S	*	*			trans	-79.5	150.7	170.8	0	0	0	0	0	110	M5	G3-M5 PolarHBondContact O-N 3.2Å
4	C	49	Very low	41.9	Very low	107 Å²	107	157.4 Å²	157.4	72%	0.723	85%	0.851	S	S	*	*			trans	-54.8	115.2	175.2	-61.4	0	0	0	0	109.9	K6	C4-K6 PolarHBondContact O-N 2.9Å; C4-K6 VanDerWaalsContact O-N 3.14Å
5	M	48.8	Very low	41.5	Very low	185 Å²	185	155.4 Å²	155.4	91%	0.911	85%	0.846	S	S	*	*			trans	-66.9	114.7	179.2	-65.6	170.4	87.8	0	0	108.3	G3 A7	G3-M5 PolarHBondContact O-N 3.2Å; M5-A7 PolarHBondContact O-N 3.46Å
6	K	47	Very low	41.2	Very low	202 Å²	202	157.3 Å²	157.3	88%	0.878	85%	0.846	S	S	*	*	P	Polyproline II helix	trans	-63.9	122.9	169.1	-153.4	168.4	-174.4	172.7	0	107.2	C4 A8	C4-K6 PolarHBondContact O-N 2.9Å; C4-K6 VanDerWaalsContact O-N 3.14Å; K6-A8 PolarHBondContact O-N 3.03Å; K6-A8 VanDerWaalsContact O-N 3.16Å
7	A	47.9	Very low	40.6	Very low	99 Å²	99	152.5 Å²	152.5	82%	0.818	84%	0.843	S	S	*	*	P	Polyproline II helix	trans	-59.3	121.1	176.2	0	0	0	0	0	109.2	M5	M5-A7 PolarHBondContact O-N 3.46Å
8	A	37.8	Very low	40.4	Very low	82 Å²	82	155.4 Å²	155.4	68%	0.678	85%	0.849	S	S	*	*	P	Polyproline II helix	trans	-75	143.7	177.3	0	0	0	0	0	109.8	K6 M10	K6-A8 PolarHBondContact O-N 3.03Å; K6-A8 VanDerWaalsContact O-N 3.16Å; A8-M10 PolarHBondContact O-N 3.1Å
9	P	42.3	Very low	39.8	Very low	123 Å²	123	151.3 Å²	151.3	80%	0.799	85%	0.846	S	S	*	*	P	Polyproline II helix	trans	-66.9	128.9	174.4	28.1	-30.8	0	0	0	108.9	K11	P9-K11 PolarHBondContact O-N 2.89Å
10	M	37.2	Very low	39.6	Very low	191 Å²	191	151.7 Å²	151.7	94%	0.941	85%	0.846	S	S	*	*	P	Polyproline II helix	trans	-67.2	116.8	175	-73.7	-165	62.9	0	0	109.3	A8	A8-M10 PolarHBondContact O-N 3.1Å
11	K	44.8	Very low	39.3	Very low	198 Å²	198	152.2 Å²	152.2	86%	0.861	85%	0.847	S	S	*	*	P	Polyproline II helix	trans	-89.6	120.2	172.8	-163.6	176.6	-176.9	-178.7	0	107.7	P9 A13	P9-K11 PolarHBondContact O-N 2.89Å; K11-A13 PolarHBondContact O-N 2.78Å
12	E	43.4	Very low	39.3	Very low	195 Å²	195	143.3 Å²	143.3	91%	0.911	83%	0.832	S	S	*	*	P	Polyproline II helix	trans	-60.8	118.5	172.4	-71	177	166.5	0	0	109.4
13	A	37.1	Very low	39.1	Very low	102 Å²	102	143.6 Å²	143.6	84%	0.843	83%	0.828	S	S	*	*			trans	-110.1	100.1	172.1	0	0	0	0	0	108.3	K11	K11-A13 PolarHBondContact O-N 2.78Å
14	N	41.6	Very low	39.1	Very low	154 Å²	154	146.5 Å²	146.5	82%	0.824	84%	0.835	S	S	*	*			trans	-76.4	127.4	155.6	-170.6	4	0	0	0	107.4
15	V	35.8	Very low	38.3	Very low	127 Å²	127	146 Å²	146	77%	0.77	84%	0.838	S	S	*	*			trans	166.8	138.7	135.2	156.7	0	0	0	0	111.7
16	H	37.4	Very low	37.7	Very low	185 Å²	185	143.8 Å²	143.8	86%	0.856	84%	0.835	S	S	*	*			trans	-33	151.8	164	-83.1	30.1	0	0	0	117.1
17	G	31	Very low	37	Very low	76 Å²	76	144.6 Å²	144.6	78%	0.784	83%	0.833	S	S	*	*			trans	140.4	126	142.1	0	0	0	0	0	116.1
18	Q	36.5	Very low	36.4	Very low	206 Å²	206	146.5 Å²	146.5	96%	0.963	84%	0.835	S	S	*	*			trans	-50.3	154.9	179.5	-63.2	166.8	-41.5	0	0	116.3
19	G	30.3	Very low	36.1	Very low	76 Å²	76	150.7 Å²	150.7	78%	0.784	84%	0.84	S	S	*	*			trans	148.8	112.6	150	0	0	0	0	0	115.8
20	N	35.5	Very low	35.6	Very low	159 Å²	159	148.5 Å²	148.5	85%	0.85	84%	0.839	S	S	*	*			trans	-46.6	144.5	172.8	-71.3	-34.4	0	0	0	114.7
21	L	33	Very low	35.4	Very low	164 Å²	164	145.2 Å²	145.2	86%	0.859	83%	0.83	S	S	*	*				-168.4	115.4	125.4	-125.4	74.2	0	0	0	113.1
22	A	32.7	Very low	34.9	Very low	97 Å²	97	143.6 Å²	143.6	80%	0.802	83%	0.83	S	S	*	*			trans	22.9	113.1	147.2	0	0	0	0	0	121.2
23	Y	32.6	Very low	34.3	Very low	224 Å²	224	142.7 Å²	142.7	88%	0.878	83%	0.826	S	S	*	*			trans	-114.8	138.5	143.5	-79.7	-86.7	0	0	0	109.1	A25	Y23-A25 PolarHBondContact O-N 2.78Å
24	P	39.8	Very low	34.1	Very low	124 Å²	124	142.5 Å²	142.5	81%	0.805	82%	0.819	S	S	*	*	P	Polyproline II helix	trans	-76	126.9	-179.9	29.1	-30.3	0	0	0	111.1
25	A	31.5	Very low	33.7	Very low	96 Å²	96	142.3 Å²	142.3	79%	0.793	82%	0.822	S	S	*	*	P	Polyproline II helix	trans	-69.7	133.3	174.5	0	0	0	0	0	111.7	Y23 R27	Y23-A25 PolarHBondContact O-N 2.78Å; A25-R27 PolarHBondContact O-N 3.44Å
26	V	36.8	Very low	33.4	Very low	139 Å²	139	143.5 Å²	143.5	84%	0.842	83%	0.825	S	S	*	*	P	Polyproline II helix	trans	-72.8	118.1	165.6	179.2	0	0	0	0	107.8	T28	V26-T28 PolarHBondContact O-N 3.2Å
27	R	31.6	Very low	33.1	Very low	219 Å²	219	138.1 Å²	138.1	83%	0.826	82%	0.819	S	S	*	*	P	Polyproline II helix	trans	-65.7	121.9	175.2	-76.9	179.9	172.1	-173.5	-2.3	110.4	A25	A25-R27 PolarHBondContact O-N 3.44Å
28	T	35.4	Very low	33.6	Very low	140 Å²	140	140.5 Å²	140.5	86%	0.859	82%	0.82	S	S	*	*	P	Polyproline II helix	trans	-89.8	123.7	155.3	45.1	0	0	0	0	108.3	V26	V26-T28 PolarHBondContact O-N 3.2Å
29	H	31.6	Very low	33.8	Very low	169 Å²	169	142.7 Å²	142.7	78%	0.782	82%	0.82	S	S	*	*	P	Polyproline II helix	trans	-94	124.2	164.3	-104.2	-90.2	0	0	0	107.8
30	G	32.1	Very low	33.8	Very low	77 Å²	77	144.2 Å²	144.2	79%	0.794	83%	0.825	S	S	*	*			trans	-176.8	75.7	178.2	0	0	0	0	0	109.8
31	T	33.1	Very low	33.5	Very low	122 Å²	122	140.2 Å²	140.2	75%	0.748	82%	0.822	S	S	*	*			trans	-78.8	124.1	177.3	-46.2	0	0	0	0	110
32	L	33.7	Very low	34.1	Very low	165 Å²	165	138 Å²	138	86%	0.864	82%	0.82	S	S	*	*			trans	-154.1	111.8	140.5	-152.2	94.2	0	0	0	111
33	E	31.7	Very low	34.3	Very low	176 Å²	176	145 Å²	145	82%	0.822	83%	0.825	S	S	*	*			trans	2.5	142.1	159.2	-58.3	179.1	146.4	0	0	122.7
34	S	32	Very low	34.8	Very low	98 Å²	98	138 Å²	138	69%	0.685	82%	0.821	S	S	*	*			trans	-85	137	176.4	177	0	0	0	0	112.2
35	V	32.8	Very low	34.8	Very low	149 Å²	149	140.3 Å²	140.3	90%	0.903	83%	0.826	S	S	*	*			trans	-137.4	129.1	153.1	172.1	0	0	0	0	109
36	N	31.1	Very low	35.1	Very low	153 Å²	153	141.3 Å²	141.3	82%	0.818	82%	0.823	S	S	*	*			trans	-93.3	139	-177.1	-92.7	-46.1	0	0	0	113.5
37	G	29.5	Very low	35.4	Very low	71 Å²	71	141.1 Å²	141.1	73%	0.732	82%	0.822	S	S	*	*			trans	109.3	158.6	139.9	0	0	0	0	0	118.5
38	P	43.1	Very low	36.1	Very low	126 Å²	126	136.4 Å²	136.4	82%	0.818	82%	0.817	S	S	*	*			cis	-134.4	157.3	-28.1	37.5	-19.8	0	0	0	115.8
39	R	39.5	Very low	36.8	Very low	252 Å²	252	132.5 Å²	132.5	95%	0.951	80%	0.796	S	S	*	*			trans	28.5	116.6	153.1	-64.5	-178.6	177.8	-179.7	-0.7	120.9
40	A	30.6	Very low	37.8	Very low	109 Å²	109	130.6 Å²	130.6	90%	0.901	79%	0.791	S	S	*	*			trans	-167.9	142.6	133.3	0	0	0	0	0	111.7
41	G	29.1	Very low	38.8	Very low	75 Å²	75	129.7 Å²	129.7	77%	0.773	78%	0.776	S	S	*	*			trans	98.3	85.2	150.4	0	0	0	0	0	117.4
42	S	46	Very low	39.7	Very low	116 Å²	116	128.2 Å²	128.2	81%	0.811	76%	0.763	S	S	*	*			trans	-46.4	130.8	150.2	46.5	0	0	0	0	112.3
43	R	36.8	Very low	41	Very low	245 Å²	245	124 Å²	124	93%	0.925	75%	0.745	S	S	*	*			trans	-165.1	127.7	144.1	-103.4	156.1	-170.8	-159.8	1.2	109.1
44	G	43.5	Very low	42.5	Very low	77 Å²	77	119.9 Å²	119.9	79%	0.794	72%	0.724	S	S	*	*			trans	-58.5	137	-170.5	0	0	0	0	0	112.6
45	L	38.9	Very low	43.8	Very low	173 Å²	173	118.9 Å²	118.9	91%	0.906	71%	0.709	S	S	*	*			trans	-100.6	99.3	164.3	-139.3	72.1	0	0	0	106.4	T47	L45-T47 PolarHBondContact O-N 3.37Å
46	T	39.1	Very low	45	Very low	117 Å²	117	117.6 Å²	117.6	72%	0.718	69%	0.693	S	S	*	*			trans	-52.5	130.9	168.5	43.5	0	0	0	0	109	T48	T46-T48 PolarHBondContact O-N 2.92Å
47	T	42.1	Very low	46.5	Very low	135 Å²	135	114 Å²	114	83%	0.828	68%	0.676	S	S	*	*			trans	-56.1	98.1	165.3	47.9	0	0	0	0	108.2	L45 S49	L45-T47 PolarHBondContact O-N 3.37Å; T47-S49 PolarHBondContact O-N 2.78Å
48	T	47.2	Very low	48.2	Very low	119 Å²	119	111.2 Å²	111.2	73%	0.73	64%	0.644	S	S	*	*			trans	-64	108.6	172.9	42.4	0	0	0	0	107.6	T46	T46-T48 PolarHBondContact O-N 2.92Å
49	S	49.6	Very low	49	Very low	59 Å²	59	109.5 Å²	109.5	41%	0.413	63%	0.625	S	S	.	*			trans	-70.2	139.1	-177.1	-178.5	0	0	0	0	109.5	T47 A51 D52 T53	T47-S49 PolarHBondContact O-N 2.78Å; S49-A51 PolarHBondContact O-N 2.89Å; S49-A51 VanDerWaalsContact O-N 3.11Å; S49-A51 PolarHBondContact OG-N 2.87Å; S49-D52 WeakPolarHBondContact O-CB 3.34Å; S49-D52 PolarHBondContact O-N 2.81Å; S49-T53 PolarHBondContact O-N 3.49Å
50	L	52.4	Low	50	Low	129 Å²	129	105.1 Å²	105.1	68%	0.675	62%	0.615	S	S	*	*	H	α-helix	trans	-55	-27.3	172.5	-85.5	139.6	0	0	0	112.6	T53 F54 M150	L50-T53 WeakPolarHBondContact CA-OG1 3.47Å; L50-T53 PolarHBondContact O-N 2.91Å; L50-T53 PolarHBondContact O-OG1 2.77Å; L50-F54 PolarHBondContact O-N 3.48Å; L50-M150 HydrophobicContact CD2-CE 4.33Å
51	A	54	Low	51.4	Low	58 Å²	58	102.5 Å²	102.5	48%	0.479	59%	0.586	S	S	.	*	H	α-helix	trans	-65.1	-40.8	173.5	0	0	0	0	0	111.8	S49 T53 F54 E55	S49-A51 PolarHBondContact O-N 2.89Å; S49-A51 VanDerWaalsContact O-N 3.11Å; S49-A51 PolarHBondContact OG-N 2.87Å; A51-T53 VanDerWaalsContact C-N 3.32Å; A51-T53 PolarHBondContact O-N 3.11Å; A51-F54 PolarHBondContact O-N 3.23Å; A51-E55 WeakPolarHBondContact O-CG 3.31Å; A51-E55 PolarHBondContact O-N 2.87Å
52	D	50.3	Low	52.9	Low	91 Å²	91	100.9 Å²	100.9	49%	0.487	56%	0.559	S	S	.	*	H	α-helix	trans	-65.6	-37.4	178.8	-70.5	-30.3	0	0	0	111.3	S49 F54 H56	S49-D52 WeakPolarHBondContact O-CB 3.34Å; S49-D52 PolarHBondContact O-N 2.81Å; D52-F54 VanDerWaalsContact C-N 3.33Å; D52-F54 PolarHBondContact O-N 3.37Å; D52-H56 WeakPolarHBondContact O-CB 3.27Å; D52-H56 PolarHBondContact O-N 3.42Å; D52-H56 VanDerWaalsContact O-N 3.07Å; D52-H56 PolarHBondContact O-ND1 2.99Å
53	T	62.2	Low	53.1	Low	77 Å²	77	99.8 Å²	99.8	47%	0.472	54%	0.544	S	S	.	.	H	α-helix	trans	-67	-34.4	176.7	49.1	0	0	0	0	112.7	S49 L50 A51 V57	S49-T53 PolarHBondContact O-N 3.49Å; L50-T53 WeakPolarHBondContact CA-OG1 3.47Å; L50-T53 PolarHBondContact O-N 2.91Å; L50-T53 PolarHBondContact O-OG1 2.77Å; A51-T53 VanDerWaalsContact C-N 3.32Å; A51-T53 PolarHBondContact O-N 3.11Å; T53-V57 WeakPolarHBondContact O-CG2 3.45Å; T53-V57 PolarHBondContact O-N 2.86Å
54	F	63.7	Low	53.9	Low	88 Å²	88	94.4 Å²	94.4	39%	0.386	53%	0.53	S	S	.	.	H	α-helix	trans	-72.9	-44.3	179.2	178.3	-103.6	0	0	0	111.8	L50 A51 D52 V57 I58 V161	L50-F54 PolarHBondContact O-N 3.48Å; A51-F54 PolarHBondContact O-N 3.23Å; D52-F54 VanDerWaalsContact C-N 3.33Å; D52-F54 PolarHBondContact O-N 3.37Å; F54-V57 PolarHBondContact O-N 2.98Å; F54-I58 HydrophobicContact CD1-CD1 3.79Å; F54-I58 HydrophobicContact CD2-CD1 4.33Å; F54-I58 HydrophobicContact CE1-CD1 3.26Å; F54-I58 HydrophobicContact CE2-CD1 3.85Å; F54-I58 HydrophobicContact CG-CD1 4.32Å; F54-I58 HydrophobicContact CZ-CD1 3.31Å; F54-I58 HydrophobicContact CZ-CG1 4.41Å; F54-I58 WeakPolarHBondContact O-CG1 3.44Å; F54-I58 PolarHBondContact O-N 3.16Å; F54-I58 VanDerWaalsContact O-N 3.13Å; F54-V161 HydrophobicContact CE1-CG1 3.81Å; F54-V161 HydrophobicContact CZ-CG1 4.29Å
55	E	58.5	Low	54.1	Low	78 Å²	78	97.1 Å²	97.1	36%	0.364	53%	0.526	S	S	.	.	H	α-helix	trans	-62.5	-42.4	177	-65.9	-63.6	158.2	0	0	111.4	A51 V57 I58 E59	A51-E55 WeakPolarHBondContact O-CG 3.31Å; A51-E55 PolarHBondContact O-N 2.87Å; E55-V57 PolarHBondContact O-N 3.15Å; E55-I58 PolarHBondContact O-N 3.23Å; E55-E59 WeakPolarHBondContact O-CB 3.38Å; E55-E59 PolarHBondContact O-N 3.07Å
56	H	57.6	Low	54.1	Low	122 Å²	122	96.6 Å²	96.6	57%	0.565	52%	0.519	S	S	*	.	H	α-helix	trans	-64	-40.1	176.2	-80.1	77.9	0	0	0	113	D52 I58 E59 E60	D52-H56 WeakPolarHBondContact O-CB 3.27Å; D52-H56 PolarHBondContact O-N 3.42Å; D52-H56 VanDerWaalsContact O-N 3.07Å; D52-H56 PolarHBondContact O-ND1 2.99Å; H56-I58 VanDerWaalsContact C-N 3.31Å; H56-I58 PolarHBondContact O-N 3.48Å; H56-E59 PolarHBondContact O-N 3.06Å; H56-E60 WeakPolarHBondContact O-CB 3.32Å; H56-E60 PolarHBondContact O-N 3.23Å
57	V	63.2	Low	53.9	Low	76 Å²	76	100.2 Å²	100.2	46%	0.461	53%	0.525	S	S	.	.	H	α-helix	trans	-64.4	-38.4	178	168.1	0	0	0	0	110.8	T53 F54 E55 L61	T53-V57 WeakPolarHBondContact O-CG2 3.45Å; T53-V57 PolarHBondContact O-N 2.86Å; F54-V57 PolarHBondContact O-N 2.98Å; E55-V57 PolarHBondContact O-N 3.15Å; V57-L61 HydrophobicContact CG1-CD1 3.99Å; V57-L61 WeakPolarHBondContact O-CB 3.43Å; V57-L61 WeakPolarHBondContact O-CD1 3.46Å; V57-L61 WeakPolarHBondContact O-CG 3.43Å; V57-L61 PolarHBondContact O-N 3.39Å
58	I	65.5	Low	53.5	Low	13 Å²	13	100.4 Å²	100.4	7%	0.067	53%	0.525	C	S	.	.	H	α-helix	trans	-71.6	-39.4	176.9	-65.9	168.5	0	0	0	111.3	F54 E55 H56 L61 L62 V161 V163	F54-I58 HydrophobicContact CD1-CD1 3.79Å; F54-I58 HydrophobicContact CD2-CD1 4.33Å; F54-I58 HydrophobicContact CE1-CD1 3.26Å; F54-I58 HydrophobicContact CE2-CD1 3.85Å; F54-I58 HydrophobicContact CG-CD1 4.32Å; F54-I58 HydrophobicContact CZ-CD1 3.31Å; F54-I58 HydrophobicContact CZ-CG1 4.41Å; F54-I58 WeakPolarHBondContact O-CG1 3.44Å; F54-I58 PolarHBondContact O-N 3.16Å; F54-I58 VanDerWaalsContact O-N 3.13Å; E55-I58 PolarHBondContact O-N 3.23Å; H56-I58 VanDerWaalsContact C-N 3.31Å; H56-I58 PolarHBondContact O-N 3.48Å; I58-L61 PolarHBondContact O-N 2.75Å; I58-L62 HydrophobicContact CG2-CD1 3.56Å; I58-L62 HydrophobicContact CG2-CG 4.08Å; I58-L62 WeakPolarHBondContact O-CB 3.46Å; I58-L62 VanDerWaalsContact O-CG 3.25Å; I58-L62 WeakPolarHBondContact O-CG 3.48Å; I58-L62 PolarHBondContact O-N 3.34Å; I58-V161 HydrophobicContact CD1-CG1 4.07Å; I58-V163 HydrophobicContact CG2-CB 4.33Å; I58-V163 HydrophobicContact CG2-CG1 3.52Å
59	E	59.9	Low	52.9	Low	91 Å²	91	105.8 Å²	105.8	43%	0.425	53%	0.532	S	S	.	.	H	α-helix	trans	-62.4	-45.3	178.6	-167.9	170	-161.9	0	0	111.7	E55 H56 L61 L62 D63	E55-E59 WeakPolarHBondContact O-CB 3.38Å; E55-E59 PolarHBondContact O-N 3.07Å; H56-E59 PolarHBondContact O-N 3.06Å; E59-L61 VanDerWaalsContact C-N 3.32Å; E59-L61 PolarHBondContact O-N 3.14Å; E59-L62 PolarHBondContact O-N 3.18Å; E59-D63 PolarHBondContact O-N 3.43Å; E59-D63 VanDerWaalsContact O-N 3.12Å
60	E	60.1	Low	52.8	Low	159 Å²	159	108.8 Å²	108.8	74%	0.743	55%	0.551	S	S	*	*	H	α-helix	trans	-59.9	-40	174.5	-173.3	175.1	-171.2	0	0	112.3	H56 L62	H56-E60 WeakPolarHBondContact O-CB 3.32Å; H56-E60 PolarHBondContact O-N 3.23Å; E60-L62 VanDerWaalsContact C-N 3.34Å; E60-L62 PolarHBondContact O-N 3.43Å
61	L	60.3	Low	52.2	Low	54 Å²	54	110 Å²	110	28%	0.283	56%	0.558	S	S	.	*	H	α-helix	trans	-74.9	-21.1	179.4	-68.4	171.7	0	0	0	113.9	V57 I58 E59 D79 L80 L87	V57-L61 HydrophobicContact CG1-CD1 3.99Å; V57-L61 WeakPolarHBondContact O-CB 3.43Å; V57-L61 WeakPolarHBondContact O-CD1 3.46Å; V57-L61 WeakPolarHBondContact O-CG 3.43Å; V57-L61 PolarHBondContact O-N 3.39Å; I58-L61 PolarHBondContact O-N 2.75Å; E59-L61 VanDerWaalsContact C-N 3.32Å; E59-L61 PolarHBondContact O-N 3.14Å; L61-D79 HydrophobicContact CD2-CB 4.41Å; L61-D79 WeakPolarHBondContact CD2-O 3.12Å; L61-L80 HydrophobicContact CB-CD2 4.48Å; L61-L80 HydrophobicContact CD2-CD2 4.47Å; L61-L87 HydrophobicContact CB-CD1 3.71Å; L61-L87 HydrophobicContact CD1-CD1 3.87Å; L61-L87 HydrophobicContact CG-CD1 4.42Å
62	L	60.1	Low	51.5	Low	41 Å²	41	114.5 Å²	114.5	22%	0.215	57%	0.569	C	S	.	*	H	α-helix	trans	-95.7	-15.6	-179.2	-69.5	178.3	0	0	0	113	I58 E59 E60 E64 L87 V163 K165	I58-L62 HydrophobicContact CG2-CD1 3.56Å; I58-L62 HydrophobicContact CG2-CG 4.08Å; I58-L62 WeakPolarHBondContact O-CB 3.46Å; I58-L62 VanDerWaalsContact O-CG 3.25Å; I58-L62 WeakPolarHBondContact O-CG 3.48Å; I58-L62 PolarHBondContact O-N 3.34Å; E59-L62 PolarHBondContact O-N 3.18Å; E60-L62 VanDerWaalsContact C-N 3.34Å; E60-L62 PolarHBondContact O-N 3.43Å; L62-E64 PolarHBondContact O-N 3.48Å; L62-L87 HydrophobicContact CD2-CD1 4.45Å; L62-V163 HydrophobicContact CD1-CB 3.71Å; L62-V163 HydrophobicContact CD1-CG1 3.98Å; L62-V163 HydrophobicContact CD1-CG2 3.93Å; L62-K165 PolarHBondContact O-NZ 3.13Å
63	D	51.1	Low	51.5	Low	93 Å²	93	119.3 Å²	119.3	50%	0.497	59%	0.589	S	S	.	*			trans	-87.7	76.4	-178.3	-79	-19.6	0	0	0	113.6	E59 K165	E59-D63 PolarHBondContact O-N 3.43Å; E59-D63 VanDerWaalsContact O-N 3.12Å; D63-K165 IonicContact OD1-NZ 2.66Å
64	E	52.9	Low	50.7	Low	133 Å²	133	122 Å²	122	62%	0.621	60%	0.6	S	S	*	*			trans	-135.5	109.9	148	-83.3	-144	133	0	0	110.9	L62 K76	L62-E64 PolarHBondContact O-N 3.48Å; E64-K76 IonicContact OE1-NZ 2.6Å; E64-K76 PolarHBondContact OE1-NZ 2.98Å; E64-K76 WeakPolarHBondContact OE2-CD 3.4Å; E64-K76 WeakPolarHBondContact OE2-CE 3.48Å; E64-K76 IonicContact OE2-NZ 3.41Å; E64-K76 PolarHBondContact OE2-NZ 3.32Å
65	D	47.4	Very low	49.9	Very low	134 Å²	134	124.2 Å²	124.2	72%	0.717	61%	0.611	S	S	*	*			trans	-143	131.2	141.5	-162.7	29.6	0	0	0	112
66	Q	38.8	Very low	49.6	Very low	161 Å²	161	126.3 Å²	126.3	75%	0.752	62%	0.619	S	S	*	*			trans	82.8	100.8	158.3	-109.6	156.5	75.3	0	0	121.1
67	K	35.5	Very low	49.2	Very low	193 Å²	193	125.2 Å²	125.2	84%	0.839	62%	0.617	S	S	*	*				163.4	141.8	86.2	-159.8	173.7	-175	176.8	0	112.3
68	V	34.2	Very low	48.5	Very low	139 Å²	139	124.3 Å²	124.3	84%	0.842	62%	0.618	S	S	*	*			trans	103.2	138.8	166.1	-166.9	0	0	0	0	116.2
69	R	33.3	Very low	47.9	Very low	232 Å²	232	129.2 Å²	129.2	88%	0.875	64%	0.644	S	S	*	*			trans	-92.3	-170.2	-155.3	-52.4	171.7	168.6	171.4	-5.1	114
70	P	48.3	Very low	48.1	Very low	123 Å²	123	127.5 Å²	127.5	80%	0.799	64%	0.638	S	S	*	*				-92.4	171.2	-99.9	37.8	-22.2	0	0	0	112.2
71	N	39.1	Very low	48.3	Very low	154 Å²	154	125.7 Å²	125.7	82%	0.824	63%	0.625	S	S	*	*			trans	94.5	86.4	176.9	-160.1	52.3	0	0	0	113.6
72	E	40	Very low	48.9	Very low	153 Å²	153	126.9 Å²	126.9	72%	0.715	64%	0.635	S	S	*	*			trans	-178.7	66.6	147.1	-85.2	-107.3	145.1	0	0	105.1
73	E	50.3	Low	49.5	Very low	192 Å²	192	130.3 Å²	130.3	90%	0.897	66%	0.662	S	S	*	*	T	Hydrogen-bonded Turn	trans	-67.5	136	164.5	-75	-178.6	154.2	0	0	107.3
74	N	44.2	Very low	50.9	Low	132 Å²	132	137.2 Å²	137.2	71%	0.706	68%	0.681	S	S	*	*	T	Hydrogen-bonded Turn	trans	109.7	-3.4	161.8	-147.5	23.2	0	0	0	119.1
75	H	48.3	Very low	52.4	Low	136 Å²	136	134.7 Å²	134.7	63%	0.63	68%	0.675	S	S	*	*	S	Bend	trans	-101.4	-24.4	177.3	-86.1	-67.5	0	0	0	115.8
76	K	50.9	Low	54.2	Low	121 Å²	121	131.5 Å²	131.5	53%	0.526	66%	0.656	S	S	.	*	H	α-helix	trans	-83.5	-27.5	-176	-65.7	-177.6	169	-166.8	0	114.2	E64 A78	E64-K76 IonicContact OE1-NZ 2.6Å; E64-K76 PolarHBondContact OE1-NZ 2.98Å; E64-K76 WeakPolarHBondContact OE2-CD 3.4Å; E64-K76 WeakPolarHBondContact OE2-CE 3.48Å; E64-K76 IonicContact OE2-NZ 3.41Å; E64-K76 PolarHBondContact OE2-NZ 3.32Å; K76-A78 PolarHBondContact O-N 3.46Å
77	D	49.6	Very low	56.3	Low	99 Å²	99	125.5 Å²	125.5	53%	0.529	63%	0.629	S	S	.	*	H	α-helix	trans	-66.6	-32.9	177.5	-67.8	-42.2	0	0	0	110.8	D79 L80 Y81	D77-D79 VanDerWaalsContact C-N 3.31Å; D77-D79 PolarHBondContact O-N 3.41Å; D77-L80 PolarHBondContact O-N 2.8Å; D77-Y81 WeakPolarHBondContact O-CD2 3.45Å; D77-Y81 WeakPolarHBondContact O-CE2 3.16Å
78	A	49.3	Very low	58.4	Low	57 Å²	57	119.8 Å²	119.8	47%	0.471	61%	0.614	S	S	.	*	H	α-helix	trans	-63	-33.9	-177.1	0	0	0	0	0	113.3	K76 L80 Y81	K76-A78 PolarHBondContact O-N 3.46Å; A78-L80 VanDerWaalsContact C-N 3.28Å; A78-L80 PolarHBondContact O-N 2.95Å; A78-Y81 PolarHBondContact O-N 3.31Å; A78-Y81 VanDerWaalsContact O-N 3.11Å
79	D	53.5	Low	60.6	Low	116 Å²	116	119 Å²	119	62%	0.62	61%	0.614	S	S	*	*	H	α-helix	trans	-71	-24.4	-177.1	-65.3	-30.6	0	0	0	112.4	L61 D77 Y81	L61-D79 HydrophobicContact CD2-CB 4.41Å; L61-D79 WeakPolarHBondContact CD2-O 3.12Å; D77-D79 VanDerWaalsContact C-N 3.31Å; D77-D79 PolarHBondContact O-N 3.41Å; D79-Y81 PolarHBondContact O-N 2.6Å
80	L	62.9	Low	62.7	Low	56 Å²	56	115 Å²	115	29%	0.293	61%	0.606	S	S	.	*	T	Hydrogen-bonded Turn	trans	-71.7	-8	173.2	-61.6	173.6	0	0	0	113.4	L61 D77 A78 M86 L87	L61-L80 HydrophobicContact CB-CD2 4.48Å; L61-L80 HydrophobicContact CD2-CD2 4.47Å; D77-L80 PolarHBondContact O-N 2.8Å; A78-L80 VanDerWaalsContact C-N 3.28Å; A78-L80 PolarHBondContact O-N 2.95Å; L80-M86 WeakPolarHBondContact O-CA 3.46Å; L80-L87 HydrophobicContact CD2-CB 4.37Å; L80-L87 HydrophobicContact CD2-CD1 4.38Å; L80-L87 PolarHBondContact O-N 2.87Å
81	Y	65.3	Low	64.1	Low	120 Å²	120	113 Å²	113	47%	0.471	59%	0.591	S	S	.	*	E	Extended strand (participates in β ladder)	trans	-118.6	94	-179.8	-56.3	-90.4	0	0	0	111	D77 A78 D79 M86	D77-Y81 WeakPolarHBondContact O-CD2 3.45Å; D77-Y81 WeakPolarHBondContact O-CE2 3.16Å; A78-Y81 PolarHBondContact O-N 3.31Å; A78-Y81 VanDerWaalsContact O-N 3.11Å; D79-Y81 PolarHBondContact O-N 2.6Å; Y81-M86 HydrophobicContact CD1-CB 4.16Å; Y81-M86 HydrophobicContact CD1-CG 3.59Å; Y81-M86 HydrophobicContact CD1-SD 3.75Å; Y81-M86 HydrophobicContact CE1-CG 3.59Å; Y81-M86 HydrophobicContact CE1-SD 3.39Å; Y81-M86 WeakPolarHBondContact CE1-SD 3.48Å
82	T	71.4	Confident	65.7	Low	80 Å²	80	107 Å²	107	49%	0.491	56%	0.56	S	S	.	*	E	Extended strand (participates in β ladder)	trans	-87.6	152.1	159.5	177.7	0	0	0	0	109.4	R84 V85	T82-R84 PolarHBondContact O-N 3.07Å; T82-V85 HydrophobicContact CG2-CB 3.57Å; T82-V85 HydrophobicContact CG2-CG2 4.3Å; T82-V85 WeakPolarHBondContact CG2-O 3.42Å; T82-V85 PolarHBondContact N-O 2.91Å; T82-V85 PolarHBondContact O-N 3.11Å; T82-V85 VanDerWaalsContact O-N 3.08Å
83	S	72.8	Confident	66.9	Low	113 Å²	113	107.2 Å²	107.2	79%	0.79	57%	0.566	S	S	*	*	T	Hydrogen-bonded Turn	trans	-55.8	-16	-172.1	-50.5	0	0	0	0	114.9
84	R	81.7	Confident	67.5	Low	238 Å²	238	105.1 Å²	105.1	90%	0.898	56%	0.556	S	S	*	*	T	Hydrogen-bonded Turn	trans	-117.6	-16.2	179.4	-62.6	-179	-175.8	-87.9	-0.5	114.7	T82	T82-R84 PolarHBondContact O-N 3.07Å
85	V	84.3	Confident	68.3	Low	80 Å²	80	101.9 Å²	101.9	49%	0.485	54%	0.542	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-141.2	133.4	-172.4	-174.6	0	0	0	0	109	T82	T82-V85 HydrophobicContact CG2-CB 3.57Å; T82-V85 HydrophobicContact CG2-CG2 4.3Å; T82-V85 WeakPolarHBondContact CG2-O 3.42Å; T82-V85 PolarHBondContact N-O 2.91Å; T82-V85 PolarHBondContact O-N 3.11Å; T82-V85 VanDerWaalsContact O-N 3.08Å
86	M	83.8	Confident	69	Low	66 Å²	66	97 Å²	97	33%	0.325	52%	0.522	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-130.5	134.2	178.8	168.3	-174.2	64.9	0	0	108.4	L80 Y81 W138	L80-M86 WeakPolarHBondContact O-CA 3.46Å; Y81-M86 HydrophobicContact CD1-CB 4.16Å; Y81-M86 HydrophobicContact CD1-CG 3.59Å; Y81-M86 HydrophobicContact CD1-SD 3.75Å; Y81-M86 HydrophobicContact CE1-CG 3.59Å; Y81-M86 HydrophobicContact CE1-SD 3.39Å; Y81-M86 WeakPolarHBondContact CE1-SD 3.48Å; M86-W138 HydrophobicContact CE-CH2 4.28Å
87	L	84.3	Confident	69.4	Low	36 Å²	36	94.6 Å²	94.6	19%	0.188	52%	0.515	C	S	.	.			trans	-94.9	132.9	168.4	-62.1	-178.8	0	0	0	109.4	L61 L62 L80 L168	L61-L87 HydrophobicContact CB-CD1 3.71Å; L61-L87 HydrophobicContact CD1-CD1 3.87Å; L61-L87 HydrophobicContact CG-CD1 4.42Å; L62-L87 HydrophobicContact CD2-CD1 4.45Å; L80-L87 HydrophobicContact CD2-CB 4.37Å; L80-L87 HydrophobicContact CD2-CD1 4.38Å; L80-L87 PolarHBondContact O-N 2.87Å; L87-L168 HydrophobicContact CD2-CD1 4.06Å
88	S	80	Confident	69.5	Low	73 Å²	73	95 Å²	95	51%	0.51	52%	0.516	S	S	.	.			trans	-142.3	143.6	178.4	177.9	0	0	0	0	110.7	Q90	S88-Q90 VanDerWaalsContact C-N 3.29Å; S88-Q90 PolarHBondContact OG-N 3.06Å; S88-Q90 VanDerWaalsContact OG-N 3.13Å; S88-Q90 PolarHBondContact OG-O 2.96Å; S88-Q90 VanDerWaalsContact OG-O 3.1Å
89	S	79.7	Confident	69.7	Low	123 Å²	123	99.1 Å²	99.1	86%	0.86	52%	0.524	S	S	*	.	S	Bend	trans	-79.8	-12.9	172.8	58.1	0	0	0	0	112.9
90	Q	78	Confident	69.7	Low	147 Å²	147	96.8 Å²	96.8	69%	0.687	51%	0.511	S	S	*	.	S	Bend	trans	-112.9	146.5	-178.6	-63.4	179.9	35	0	0	110.9	S88	S88-Q90 VanDerWaalsContact C-N 3.29Å; S88-Q90 PolarHBondContact OG-N 3.06Å; S88-Q90 VanDerWaalsContact OG-N 3.13Å; S88-Q90 PolarHBondContact OG-O 2.96Å; S88-Q90 VanDerWaalsContact OG-O 3.1Å
91	V	77.3	Confident	69.3	Low	80 Å²	80	101.2 Å²	101.2	49%	0.485	53%	0.534	S	S	.	.			trans	-64.9	125.5	171	-179.3	0	0	0	0	107.5	L93 Y171	V91-L93 PolarHBondContact O-N 3.35Å; V91-L93 VanDerWaalsContact O-N 3.09Å; V91-Y171 HydrophobicContact CG1-CE1 4.45Å
92	P	71.8	Confident	68.8	Low	29 Å²	29	102.3 Å²	102.3	19%	0.188	54%	0.544	C	S	.	.			trans	-69	115	-178.3	28.4	-34	0	0	0	109.4	W138	P92-W138 HydrophobicContact CB-CD2 4.12Å; P92-W138 HydrophobicContact CB-CH2 3.81Å; P92-W138 HydrophobicContact CB-CZ2 3.2Å; P92-W138 HydrophobicContact CB-CZ3 4.46Å; P92-W138 HydrophobicContact CG-CD2 3.68Å; P92-W138 VanDerWaalsContact CG-CE2 3.49Å; P92-W138 HydrophobicContact CG-CE3 3.85Å; P92-W138 HydrophobicContact CG-CG 4.34Å; P92-W138 HydrophobicContact CG-CH2 3.66Å; P92-W138 HydrophobicContact CG-CZ2 3.48Å; P92-W138 VanDerWaalsContact CG-CZ2 3.48Å; P92-W138 HydrophobicContact CG-CZ3 3.84Å
93	L	66.3	Low	68	Low	158 Å²	158	102.4 Å²	102.4	83%	0.827	54%	0.539	S	S	*	.			trans	-85.7	-27.1	179.3	-61.6	178.4	0	0	0	111.7	V91	V91-L93 PolarHBondContact O-N 3.35Å; V91-L93 VanDerWaalsContact O-N 3.09Å
94	E	62.2	Low	67.1	Low	148 Å²	148	103.4 Å²	103.4	69%	0.692	53%	0.526	S	S	*	.	S	Bend	trans	-119.7	147.9	-178.9	-70.6	-177.1	169.3	0	0	110.8	W138	E94-W138 PolarHBondContact O-NE1 3.26Å
95	P	61.8	Low	65.8	Low	64 Å²	64	98.4 Å²	98.4	42%	0.416	51%	0.511	S	S	.	.	P	Polyproline II helix	trans	-51.9	136.6	168.8	20.2	-33.3	0	0	0	111.8	L97 Y173	P95-L97 PolarHBondContact O-N 3.06Å; P95-Y173 HydrophobicContact CB-CD2 4.29Å; P95-Y173 HydrophobicContact CB-CE1 4.36Å; P95-Y173 HydrophobicContact CB-CE2 3.23Å; P95-Y173 WeakPolarHBondContact CB-OH 3.28Å
96	P	62.7	Low	64.6	Low	33 Å²	33	99 Å²	99	21%	0.214	51%	0.511	C	S	.	.	P	Polyproline II helix	trans	-65	135.9	167.8	29.4	-25.9	0	0	0	107.9	L98 L100 W138 Y173	P96-L98 PolarHBondContact O-N 3.29Å; P96-L100 HydrophobicContact CB-CD2 4.36Å; P96-W138 VanDerWaalsContact CD-CZ2 3.45Å; P96-W138 HydrophobicContact CG-CH2 4.2Å; P96-W138 HydrophobicContact CG-CZ2 4.09Å; P96-Y173 VanDerWaalsContact CD-CD1 3.47Å; P96-Y173 VanDerWaalsContact CD-CD2 3.46Å; P96-Y173 HydrophobicContact CG-CD1 3.52Å; P96-Y173 HydrophobicContact CG-CD2 4.33Å; P96-Y173 HydrophobicContact CG-CE1 3.91Å; P96-Y173 HydrophobicContact CG-CG 3.73Å
97	L	58.1	Low	63.3	Low	70 Å²	70	102.3 Å²	102.3	37%	0.366	52%	0.521	S	S	.	.	P	Polyproline II helix	trans	-60.1	125.1	177.5	-57.9	179.8	0	0	0	108.3	P95 F99 L100 E103 Y107	P95-L97 PolarHBondContact O-N 3.06Å; L97-F99 PolarHBondContact O-N 3.24Å; L97-L100 PolarHBondContact O-N 3.38Å; L97-E103 HydrophobicContact CB-CB 4.45Å; L97-E103 HydrophobicContact CD1-CB 4.44Å; L97-Y107 HydrophobicContact CD1-CG 4.36Å
98	L	52.5	Low	61.9	Low	107 Å²	107	104.4 Å²	104.4	56%	0.56	53%	0.532	S	S	*	.	S	Bend	trans	-61.2	-12.3	-170.8	-72.8	171.3	0	0	0	113.2	P96 Y173	P96-L98 PolarHBondContact O-N 3.29Å; L98-Y173 HydrophobicContact CD2-CE1 3.76Å; L98-Y173 HydrophobicContact CG-CE1 4.45Å
99	F	53.4	Low	61	Low	144 Å²	144	104.9 Å²	104.9	63%	0.632	53%	0.529	S	S	*	.	S	Bend	trans	-123.9	72.8	170.4	-60.8	-81.3	0	0	0	109.8	L97 L101 E102 E103	L97-F99 PolarHBondContact O-N 3.24Å; F99-L101 PolarHBondContact O-N 3.19Å; F99-E102 PolarHBondContact O-N 3.12Å; F99-E103 HydrophobicContact CB-CB 4.19Å; F99-E103 VanDerWaalsContact O-CB 3.26Å; F99-E103 WeakPolarHBondContact O-CB 3.22Å; F99-E103 PolarHBondContact O-N 3.49Å
100	L	53.1	Low	59.9	Low	67 Å²	67	100 Å²	100	35%	0.351	50%	0.496	S	S	.	.	T	Hydrogen-bonded Turn	trans	-48.9	-23.1	-174	-84	169.5	0	0	0	115.8	P96 L97 Y104	P96-L100 HydrophobicContact CB-CD2 4.36Å; L97-L100 PolarHBondContact O-N 3.38Å; L100-Y104 WeakPolarHBondContact O-CB 3.37Å
101	L	55.6	Low	58.9	Low	149 Å²	149	95.2 Å²	95.2	78%	0.78	48%	0.481	S	S	*	.	T	Hydrogen-bonded Turn	trans	-103.5	-51.7	-176.7	-72.3	159.9	0	0	0	112.3	F99 K105	F99-L101 PolarHBondContact O-N 3.19Å; L101-K105 PolarHBondContact O-N 3.02Å
102	E	54.5	Low	58.2	Low	143 Å²	143	98.3 Å²	98.3	67%	0.668	50%	0.495	S	S	*	.	H	α-helix	trans	-67.9	-41.6	-178.5	-149.4	73.6	-148.1	0	0	111.2	F99 N106	F99-E102 PolarHBondContact O-N 3.12Å; E102-N106 PolarHBondContact O-N 3.19Å; E102-N106 PolarHBondContact O-ND2 2.98Å
103	E	54.5	Low	57.7	Low	83 Å²	83	100.6 Å²	100.6	39%	0.388	51%	0.505	S	S	.	.	H	α-helix	trans	-87.8	-24.5	-174.6	-143.2	162.4	-140.2	0	0	112.1	L97 F99 N106 Y107	L97-E103 HydrophobicContact CB-CB 4.45Å; L97-E103 HydrophobicContact CD1-CB 4.44Å; F99-E103 HydrophobicContact CB-CB 4.19Å; F99-E103 VanDerWaalsContact O-CB 3.26Å; F99-E103 WeakPolarHBondContact O-CB 3.22Å; F99-E103 PolarHBondContact O-N 3.49Å; E103-N106 CarbonylContact O-C 3.5Å; E103-N106 PolarHBondContact O-N 2.66Å; E103-Y107 WeakPolarHBondContact O-CA 3.45Å; E103-Y107 WeakPolarHBondContact O-CB 3.14Å; E103-Y107 PolarHBondContact O-N 2.93Å
104	Y	53.5	Low	57.9	Low	133 Å²	133	96.5 Å²	96.5	52%	0.522	49%	0.489	S	S	.	.	H	α-helix	trans	-67.3	-41.8	169.7	179.6	-106.1	0	0	0	111.7	L100 Y107 L108	L100-Y104 WeakPolarHBondContact O-CB 3.37Å; Y104-Y107 PolarHBondContact O-N 3.5Å; Y104-L108 HydrophobicContact CD1-CD1 3.77Å; Y104-L108 HydrophobicContact CD1-CG 4.19Å; Y104-L108 HydrophobicContact CD2-CG 4.4Å; Y104-L108 HydrophobicContact CE1-CD1 3.22Å; Y104-L108 HydrophobicContact CE1-CG 3.88Å; Y104-L108 HydrophobicContact CE2-CD1 4.28Å; Y104-L108 HydrophobicContact CE2-CD2 4.18Å; Y104-L108 HydrophobicContact CE2-CG 4.1Å; Y104-L108 HydrophobicContact CG-CD1 4.5Å; Y104-L108 HydrophobicContact CG-CG 4.44Å; Y104-L108 WeakPolarHBondContact O-CB 3.33Å; Y104-L108 WeakPolarHBondContact O-CG 3.13Å; Y104-L108 PolarHBondContact O-N 2.78Å
105	K	54.5	Low	57.9	Low	134 Å²	134	95.1 Å²	95.1	58%	0.583	48%	0.484	S	S	*	.	H	α-helix	trans	-61.4	-46.6	172.6	-169.1	-174.7	174.4	75.1	0	110.6	L101 Y107 L108 D109	L101-K105 PolarHBondContact O-N 3.02Å; K105-Y107 VanDerWaalsContact C-N 3.32Å; K105-Y107 PolarHBondContact O-N 2.87Å; K105-L108 PolarHBondContact O-N 2.72Å; K105-D109 VanDerWaalsContact O-CB 3.28Å; K105-D109 WeakPolarHBondContact O-CB 3.48Å; K105-D109 PolarHBondContact O-N 2.8Å
106	N	59	Low	58.3	Low	93 Å²	93	101.4 Å²	101.4	50%	0.497	50%	0.499	S	S	.	.	H	α-helix	trans	-63.6	-34.6	175.4	-67.8	-30.8	0	0	0	112.9	E102 E103 A110	E102-N106 PolarHBondContact O-N 3.19Å; E102-N106 PolarHBondContact O-ND2 2.98Å; E103-N106 CarbonylContact O-C 3.5Å; E103-N106 PolarHBondContact O-N 2.66Å; N106-A110 WeakPolarHBondContact O-CB 3.43Å; N106-A110 PolarHBondContact O-N 3.08Å
107	Y	55.6	Low	58.5	Low	134 Å²	134	102.9 Å²	102.9	53%	0.525	51%	0.508	S	S	.	.	H	α-helix	trans	-74.3	-41.8	177.7	179.1	-96.3	0	0	0	112	L97 E103 Y104 K105 D109 A110 A111	L97-Y107 HydrophobicContact CD1-CG 4.36Å; E103-Y107 WeakPolarHBondContact O-CA 3.45Å; E103-Y107 WeakPolarHBondContact O-CB 3.14Å; E103-Y107 PolarHBondContact O-N 2.93Å; Y104-Y107 PolarHBondContact O-N 3.5Å; K105-Y107 VanDerWaalsContact C-N 3.32Å; K105-Y107 PolarHBondContact O-N 2.87Å; Y107-D109 VanDerWaalsContact C-N 3.33Å; Y107-A110 CarbonylContact O-C 3.48Å; Y107-A110 PolarHBondContact O-N 3.4Å; Y107-A111 WeakPolarHBondContact O-CB 3.36Å; Y107-A111 PolarHBondContact O-N 3.21Å
108	L	56.5	Low	58.7	Low	80 Å²	80	104 Å²	104	42%	0.419	51%	0.507	S	S	.	.	H	α-helix	trans	-62.7	-43.3	172	-74.3	-176.7	0	0	0	110.7	Y104 K105 A110 A111 N112	Y104-L108 HydrophobicContact CD1-CD1 3.77Å; Y104-L108 HydrophobicContact CD1-CG 4.19Å; Y104-L108 HydrophobicContact CD2-CG 4.4Å; Y104-L108 HydrophobicContact CE1-CD1 3.22Å; Y104-L108 HydrophobicContact CE1-CG 3.88Å; Y104-L108 HydrophobicContact CE2-CD1 4.28Å; Y104-L108 HydrophobicContact CE2-CD2 4.18Å; Y104-L108 HydrophobicContact CE2-CG 4.1Å; Y104-L108 HydrophobicContact CG-CD1 4.5Å; Y104-L108 HydrophobicContact CG-CG 4.44Å; Y104-L108 WeakPolarHBondContact O-CB 3.33Å; Y104-L108 WeakPolarHBondContact O-CG 3.13Å; Y104-L108 PolarHBondContact O-N 2.78Å; K105-L108 PolarHBondContact O-N 2.72Å; L108-A110 VanDerWaalsContact C-N 3.32Å; L108-A110 PolarHBondContact O-N 3.22Å; L108-A111 PolarHBondContact O-N 3.25Å; L108-N112 PolarHBondContact O-N 2.87Å; L108-N112 VanDerWaalsContact O-N 3.09Å
109	D	60.3	Low	59	Low	83 Å²	83	106.6 Å²	106.6	44%	0.444	51%	0.509	S	S	.	.	H	α-helix	trans	-61.5	-41.8	173.6	-73.4	-19.2	0	0	0	110.4	K105 Y107 N112 M113	K105-D109 VanDerWaalsContact O-CB 3.28Å; K105-D109 WeakPolarHBondContact O-CB 3.48Å; K105-D109 PolarHBondContact O-N 2.8Å; Y107-D109 VanDerWaalsContact C-N 3.33Å; D109-N112 PolarHBondContact O-N 3.49Å; D109-M113 WeakPolarHBondContact O-CG 3.25Å; D109-M113 PolarHBondContact O-N 3.25Å
110	A	57.5	Low	59.3	Low	20 Å²	20	106.2 Å²	106.2	17%	0.165	51%	0.509	C	S	.	.	H	α-helix	trans	-72.5	-31.2	176.1	0	0	0	0	0	114	N106 Y107 L108 N112 M113 R118	N106-A110 WeakPolarHBondContact O-CB 3.43Å; N106-A110 PolarHBondContact O-N 3.08Å; Y107-A110 CarbonylContact O-C 3.48Å; Y107-A110 PolarHBondContact O-N 3.4Å; L108-A110 VanDerWaalsContact C-N 3.32Å; L108-A110 PolarHBondContact O-N 3.22Å; A110-N112 PolarHBondContact O-N 2.81Å; A110-M113 WeakPolarHBondContact O-CB 3.36Å; A110-M113 PolarHBondContact O-N 3.2Å; A110-R118 WeakPolarHBondContact O-CD 3.44Å; A110-R118 WeakPolarHBondContact O-CG 3.15Å; A110-R118 PolarHBondContact O-NE 3.02Å
111	A	56.7	Low	59.4	Low	47 Å²	47	105.2 Å²	105.2	39%	0.388	51%	0.508	S	S	.	.	H	α-helix	trans	-66.9	-28.8	174.1	0	0	0	0	0	110.3	Y107 L108 R118	Y107-A111 WeakPolarHBondContact O-CB 3.36Å; Y107-A111 PolarHBondContact O-N 3.21Å; L108-A111 PolarHBondContact O-N 3.25Å; A111-R118 PolarHBondContact O-NH2 3.13Å
112	N	61.9	Low	59.4	Low	145 Å²	145	101.4 Å²	101.4	78%	0.775	49%	0.488	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82	-9.1	170.9	-157.3	-0.3	0	0	0	113.6	L108 D109 A110	L108-N112 PolarHBondContact O-N 2.87Å; L108-N112 VanDerWaalsContact O-N 3.09Å; D109-N112 PolarHBondContact O-N 3.49Å; A110-N112 PolarHBondContact O-N 2.81Å
113	M	62.4	Low	59.7	Low	78 Å²	78	97.9 Å²	97.9	38%	0.384	48%	0.478	S	S	.	.	S	Bend	trans	-81.3	148.7	178.4	-71.7	-176.9	-170.6	0	0	112.8	D109 A110 V117 R118	D109-M113 WeakPolarHBondContact O-CG 3.25Å; D109-M113 PolarHBondContact O-N 3.25Å; A110-M113 WeakPolarHBondContact O-CB 3.36Å; A110-M113 PolarHBondContact O-N 3.2Å; M113-V117 HydrophobicContact CB-CB 4.03Å; M113-V117 HydrophobicContact CB-CG1 3.92Å; M113-V117 HydrophobicContact CG-CG1 3.98Å; M113-V117 HydrophobicContact SD-CB 4.42Å; M113-V117 HydrophobicContact SD-CG1 3.32Å; M113-V117 WeakPolarHBondContact SD-CG1 3.47Å; M113-R118 HydrophobicContact CB-CG 4.26Å; M113-R118 PolarHBondContact O-NE 2.91Å; M113-R118 PolarHBondContact O-NH1 2.83Å; M113-R118 PolarHBondContact O-NH2 3.09Å
114	S	70	Confident	59.9	Low	71 Å²	71	97.4 Å²	97.4	50%	0.497	49%	0.488	S	S	.	.			trans	-60.8	153.4	175.8	73.3	0	0	0	0	112.4	R116 V117 R118	S114-R116 PolarHBondContact O-N 2.76Å; S114-V117 PolarHBondContact O-N 2.89Å; S114-V117 WeakPolarHBondContact OG-CG2 3.09Å; S114-R118 PolarHBondContact O-N 3.19Å
115	M	62.6	Low	60	Low	119 Å²	119	99.2 Å²	99.2	59%	0.586	49%	0.494	S	S	*	.	H	α-helix	trans	-50.2	-29.5	175.5	-77.9	-65.9	-70.2	0	0	113.9	R118 R119	M115-R118 PolarHBondContact SD-NH1 3.1Å; M115-R119 WeakPolarHBondContact O-CG 3.45Å
116	R	69.4	Low	60.4	Low	197 Å²	197	101.1 Å²	101.1	74%	0.743	50%	0.497	S	S	*	.	H	α-helix	trans	-70.2	-42.3	176	-177.9	-179.7	-72.1	173.1	-2.7	111.6	S114 H120	S114-R116 PolarHBondContact O-N 2.76Å; R116-H120 PolarHBondContact O-CD2 2.75Å; R116-H120 VanDerWaalsContact O-CD2 3.29Å
117	V	66.4	Low	60.3	Low	64 Å²	64	99.2 Å²	99.2	39%	0.388	50%	0.5	S	S	.	.	H	α-helix	trans	-73.4	-39.5	-178.5	177.5	0	0	0	0	110.8	M113 S114 R119 H120 S121	M113-V117 HydrophobicContact CB-CB 4.03Å; M113-V117 HydrophobicContact CB-CG1 3.92Å; M113-V117 HydrophobicContact CG-CG1 3.98Å; M113-V117 HydrophobicContact SD-CB 4.42Å; M113-V117 HydrophobicContact SD-CG1 3.32Å; M113-V117 WeakPolarHBondContact SD-CG1 3.47Å; S114-V117 PolarHBondContact O-N 2.89Å; S114-V117 WeakPolarHBondContact OG-CG2 3.09Å; V117-R119 PolarHBondContact O-N 3.34Å; V117-H120 WeakPolarHBondContact O-CA 3.42Å; V117-H120 PolarHBondContact O-N 3.11Å; V117-S121 PolarHBondContact O-N 3.01Å
118	R	62.5	Low	60.9	Low	93 Å²	93	98.9 Å²	98.9	35%	0.351	50%	0.503	S	S	.	.	H	α-helix	trans	-57.8	-34.1	175.5	-63.5	-168	-157.7	104.7	-3.6	113.7	A110 A111 M113 S114 M115 H120 S121	A110-R118 WeakPolarHBondContact O-CD 3.44Å; A110-R118 WeakPolarHBondContact O-CG 3.15Å; A110-R118 PolarHBondContact O-NE 3.02Å; A111-R118 PolarHBondContact O-NH2 3.13Å; M113-R118 HydrophobicContact CB-CG 4.26Å; M113-R118 PolarHBondContact O-NE 2.91Å; M113-R118 PolarHBondContact O-NH1 2.83Å; M113-R118 PolarHBondContact O-NH2 3.09Å; S114-R118 PolarHBondContact O-N 3.19Å; M115-R118 PolarHBondContact SD-NH1 3.1Å; R118-H120 PolarHBondContact O-N 3.47Å; R118-S121 WeakPolarHBondContact CA-OG 3.23Å; R118-S121 PolarHBondContact O-N 3.47Å; R118-S121 PolarHBondContact O-OG 2.73Å
119	R	59	Low	61.7	Low	161 Å²	161	99.5 Å²	99.5	61%	0.608	51%	0.506	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.3	-18	176.2	-72.1	177.2	-174.7	166.8	2	113.8	M115 V117 R125	M115-R119 WeakPolarHBondContact O-CG 3.45Å; V117-R119 PolarHBondContact O-N 3.34Å; R119-R125 PolarHBondContact O-NH1 3.38Å
120	H	59.2	Low	62.6	Low	137 Å²	137	98.6 Å²	98.6	63%	0.634	51%	0.506	S	S	*	.	T	Hydrogen-bonded Turn	trans	-97.5	-16	176.1	-75.2	-70.3	0	0	0	113.2	R116 V117 R118	R116-H120 PolarHBondContact O-CD2 2.75Å; R116-H120 VanDerWaalsContact O-CD2 3.29Å; V117-H120 WeakPolarHBondContact O-CA 3.42Å; V117-H120 PolarHBondContact O-N 3.11Å; R118-H120 PolarHBondContact O-N 3.47Å
121	S	55.6	Low	63.9	Low	46 Å²	46	102.1 Å²	102.1	32%	0.322	53%	0.526	S	S	.	.			trans	-90.5	-3.2	177.7	61.5	0	0	0	0	113.8	V117 R118 P123	V117-S121 PolarHBondContact O-N 3.01Å; R118-S121 WeakPolarHBondContact CA-OG 3.23Å; R118-S121 PolarHBondContact O-N 3.47Å; R118-S121 PolarHBondContact O-OG 2.73Å; S121-P123 WeakPolarHBondContact O-CD 3.29Å; S121-P123 VanDerWaalsContact O-N 3.12Å
122	D	56.3	Low	65.2	Low	69 Å²	69	102.7 Å²	102.7	37%	0.369	53%	0.526	S	S	.	.			trans	-58.3	111.4	173.1	-178.4	-6.3	0	0	0	109.8	A124 R125 R126	D122-A124 PolarHBondContact O-N 3.31Å; D122-A124 WeakPolarHBondContact OD1-CB 3.45Å; D122-A124 PolarHBondContact OD1-N 3.41Å; D122-A124 VanDerWaalsContact OD1-N 3.08Å; D122-R125 HydrophobicContact CB-CB 4.24Å; D122-R125 HydrophobicContact CB-CG 4.06Å; D122-R125 PolarHBondContact O-N 3.47Å; D122-R126 PolarHBondContact O-N 2.68Å; D122-R126 VanDerWaalsContact O-N 3.13Å
123	P	59.9	Low	66.2	Low	69 Å²	69	97.8 Å²	97.8	45%	0.448	50%	0.5	S	S	.	.	H	α-helix	trans	-57.3	-33.4	-177	-24.7	35.4	0	0	0	112.5	S121 R125 R126 G127 E128	S121-P123 WeakPolarHBondContact O-CD 3.29Å; S121-P123 VanDerWaalsContact O-N 3.12Å; P123-R125 PolarHBondContact O-N 3.22Å; P123-R126 PolarHBondContact O-N 3.2Å; P123-R126 VanDerWaalsContact O-N 3.09Å; P123-G127 PolarHBondContact O-N 2.93Å; P123-E128 PolarHBondContact O-N 2.66Å
124	A	58.4	Low	67.3	Low	72 Å²	72	97.2 Å²	97.2	60%	0.595	50%	0.504	S	S	*	.	H	α-helix	trans	-64.9	-27.7	177.7	0	0	0	0	0	112.3	D122	D122-A124 PolarHBondContact O-N 3.31Å; D122-A124 WeakPolarHBondContact OD1-CB 3.45Å; D122-A124 PolarHBondContact OD1-N 3.41Å; D122-A124 VanDerWaalsContact OD1-N 3.08Å
125	R	56.7	Low	68	Low	172 Å²	172	97.9 Å²	97.9	65%	0.649	50%	0.501	S	S	*	.	H	α-helix	trans	-90.7	-16.1	175.6	-60.2	-173.8	76.3	-151.9	4.2	113.2	R119 D122 P123	R119-R125 PolarHBondContact O-NH1 3.38Å; D122-R125 HydrophobicContact CB-CB 4.24Å; D122-R125 HydrophobicContact CB-CG 4.06Å; D122-R125 PolarHBondContact O-N 3.47Å; P123-R125 PolarHBondContact O-N 3.22Å
126	R	62.1	Low	69.2	Low	173 Å²	173	94.1 Å²	94.1	65%	0.653	49%	0.486	S	S	*	.	H	α-helix	trans	-86.1	-13	176.4	-142.5	-178	-163	166.3	3.7	113.2	D122 P123	D122-R126 PolarHBondContact O-N 2.68Å; D122-R126 VanDerWaalsContact O-N 3.13Å; P123-R126 PolarHBondContact O-N 3.2Å; P123-R126 VanDerWaalsContact O-N 3.09Å
127	G	57.5	Low	70	Confident	53 Å²	53	89 Å²	89	55%	0.546	47%	0.47	S	S	.	.	T	Hydrogen-bonded Turn	trans	86.3	10.8	-179.9	0	0	0	0	0	114	P123 L129	P123-G127 PolarHBondContact O-N 2.93Å; G127-L129 PolarHBondContact O-N 3.45Å
128	E	67.8	Low	71.1	Confident	128 Å²	128	88.9 Å²	88.9	60%	0.598	46%	0.463	S	S	*	.			trans	-81.9	76.1	172.3	-67.9	174.1	-153.8	0	0	108.3	P123	P123-E128 PolarHBondContact O-N 2.66Å
129	L	73.4	Confident	72.4	Confident	93 Å²	93	85 Å²	85	49%	0.487	45%	0.449	S	S	.	.			trans	-87.4	137.9	177.6	-72	151.2	0	0	0	109.7	G127	G127-L129 PolarHBondContact O-N 3.45Å
130	S	78.3	Confident	74	Confident	63 Å²	63	79.2 Å²	79.2	44%	0.441	43%	0.432	S	S	.	.			trans	-64.9	149.4	170.1	58.6	0	0	0	0	110.7	C132	S130-C132 VanDerWaalsContact C-N 3.26Å; S130-C132 VanDerWaalsContact CB-O 3.28Å; S130-C132 WeakPolarHBondContact CB-O 3.41Å; S130-C132 PolarHBondContact O-N 3.46Å; S130-C132 PolarHBondContact OG-O 2.89Å
131	V	85.3	Confident	75.4	Confident	95 Å²	95	73 Å²	73	58%	0.576	41%	0.405	S	S	*	.	S	Bend	trans	-63.9	-36	176.3	172.5	0	0	0	0	110.9	C187 R188	V131-C187 HydrophobicContact CG1-CB 3.36Å; V131-R188 PolarHBondContact O-N 3.39Å
132	C	83.8	Confident	76.9	Confident	59 Å²	59	74.1 Å²	74.1	40%	0.399	42%	0.416	S	S	.	.	S	Bend	trans	-122.9	136	171.6	-65.6	0	0	0	0	109.7	S130 C187	S130-C132 VanDerWaalsContact C-N 3.26Å; S130-C132 VanDerWaalsContact CB-O 3.28Å; S130-C132 WeakPolarHBondContact CB-O 3.41Å; S130-C132 PolarHBondContact O-N 3.46Å; S130-C132 PolarHBondContact OG-O 2.89Å; C132-C187 PolarHBondContact SG-SG 2.98Å
133	D	84.6	Confident	78.5	Confident	42 Å²	42	76.6 Å²	76.6	23%	0.225	43%	0.43	C	S	.	.			trans	-72.6	138.8	169	-63.1	-28.5	0	0	0	109.2	N178	D133-N178 HydrophobicContact CB-CB 3.69Å; D133-N178 WeakPolarHBondContact O-CB 3.48Å; D133-N178 PolarHBondContact O-N 3.01Å
134	S	84.9	Confident	80	Confident	66 Å²	66	76.9 Å²	76.9	46%	0.462	42%	0.424	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-129.4	153.3	177.1	58.1	0	0	0	0	111.1	K176	S134-K176 CarbonylContact C-O 3.54Å; S134-K176 VanDerWaalsContact CA-O 3.23Å; S134-K176 WeakPolarHBondContact CA-O 3.36Å; S134-K176 WeakPolarHBondContact CB-O 3.5Å
135	I	85.1	Confident	81.7	Confident	85 Å²	85	80.5 Å²	80.5	44%	0.436	43%	0.426	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-120.6	131	174.5	-57.9	169.5	0	0	0	106.7	T175 K176 N178	I135-T175 WeakPolarHBondContact O-CA 3.22Å; I135-K176 PolarHBondContact N-O 2.89Å; I135-K176 PolarHBondContact O-N 3.32Å; I135-N178 HydrophobicContact CD1-CB 4.09Å; I135-N178 HydrophobicContact CG1-CB 4.02Å
136	S	86.6	Confident	83.5	Confident	40 Å²	40	76.1 Å²	76.1	28%	0.28	42%	0.419	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-121.1	139.4	-179.9	-49.6	0	0	0	0	111.2	Y173 E174 T175	S136-Y173 WeakPolarHBondContact CB-OH 2.87Å; S136-Y173 PolarHBondContact OG-OH 2.98Å; S136-E174 CarbonylContact C-O 3.59Å; S136-E174 VanDerWaalsContact CA-O 3.22Å; S136-E174 WeakPolarHBondContact CA-O 3.38Å; S136-T175 WeakPolarHBondContact CB-OG1 3.32Å; S136-T175 WeakPolarHBondContact OG-CB 3.4Å; S136-T175 VanDerWaalsContact OG-CG2 3.29Å; S136-T175 WeakPolarHBondContact OG-CG2 3.4Å; S136-T175 PolarHBondContact OG-OG1 2.9Å
137	E	87.2	Confident	85.1	Confident	88 Å²	88	69.4 Å²	69.4	41%	0.411	40%	0.4	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-147.3	151.5	-173.1	62.5	-175.5	167.2	0	0	111.7	V139 E174 K176	E137-V139 HydrophobicContact CG-CG2 3.81Å; E137-E174 PolarHBondContact N-O 3.46Å; E137-E174 PolarHBondContact O-N 3.31Å; E137-K176 IonicContact OE1-NZ 3.69Å; E137-K176 PolarHBondContact OE1-NZ 3.04Å
138	W	88.4	Confident	86.9	Confident	63 Å²	63	71.7 Å²	71.7	24%	0.239	40%	0.404	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-85.4	118.5	168.5	-72.9	109.1	0	0	0	109.5	M86 P92 E94 P96 F172 Y173	M86-W138 HydrophobicContact CE-CH2 4.28Å; P92-W138 HydrophobicContact CB-CD2 4.12Å; P92-W138 HydrophobicContact CB-CH2 3.81Å; P92-W138 HydrophobicContact CB-CZ2 3.2Å; P92-W138 HydrophobicContact CB-CZ3 4.46Å; P92-W138 HydrophobicContact CG-CD2 3.68Å; P92-W138 VanDerWaalsContact CG-CE2 3.49Å; P92-W138 HydrophobicContact CG-CE3 3.85Å; P92-W138 HydrophobicContact CG-CG 4.34Å; P92-W138 HydrophobicContact CG-CH2 3.66Å; P92-W138 HydrophobicContact CG-CZ2 3.48Å; P92-W138 VanDerWaalsContact CG-CZ2 3.48Å; P92-W138 HydrophobicContact CG-CZ3 3.84Å; E94-W138 PolarHBondContact O-NE1 3.26Å; P96-W138 VanDerWaalsContact CD-CZ2 3.45Å; P96-W138 HydrophobicContact CG-CH2 4.2Å; P96-W138 HydrophobicContact CG-CZ2 4.09Å; W138-F172 CarbonylContact C-O 3.59Å; W138-F172 WeakPolarHBondContact CA-O 3.35Å; W138-Y173 HydrophobicContact CD2-CD2 4.12Å; W138-Y173 HydrophobicContact CE3-CD2 4.46Å; W138-Y173 HydrophobicContact CZ2-CD2 4.37Å
139	V	91	Very high	88.2	Confident	10 Å²	10	68.7 Å²	68.7	6%	0.061	39%	0.392	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-107.9	137.3	-178.8	-175.4	0	0	0	0	109.3	E137 D143 K144 F172 E174	E137-V139 HydrophobicContact CG-CG2 3.81Å; V139-D143 HydrophobicContact CG1-CB 4.09Å; V139-K144 HydrophobicContact CG1-CB 3.7Å; V139-K144 HydrophobicContact CG1-CD 4.42Å; V139-F172 HydrophobicContact CB-CB 4.34Å; V139-F172 PolarHBondContact N-O 3.41Å; V139-F172 PolarHBondContact O-N 3.09Å; V139-E174 HydrophobicContact CB-CG 4.41Å; V139-E174 HydrophobicContact CG2-CB 4.02Å; V139-E174 HydrophobicContact CG2-CG 3.88Å
140	T	91.3	Very high	89.1	Confident	40 Å²	40	72.8 Å²	72.8	25%	0.245	41%	0.41	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-109.4	167	176.5	68.9	0	0	0	0	111.4	A142 D143 K144 Y171	T140-A142 PolarHBondContact O-N 3.3Å; T140-A142 VanDerWaalsContact O-N 3.15Å; T140-A142 WeakPolarHBondContact OG1-CB 3.5Å; T140-A142 PolarHBondContact OG1-N 3Å; T140-D143 PolarHBondContact O-N 3.03Å; T140-D143 PolarHBondContact OG1-OD2 2.71Å; T140-K144 PolarHBondContact O-N 3.44Å; T140-Y171 HydrophobicContact CG2-CD1 3.69Å; T140-Y171 HydrophobicContact CG2-CE1 3.66Å
141	A	89.4	Confident	89.9	Confident	8 Å²	8	74.5 Å²	74.5	7%	0.066	42%	0.423	C	S	.	.	T	Hydrogen-bonded Turn	trans	-63.2	-16.2	173.8	0	0	0	0	0	113.6	D143 K144 K145 V157 E159	A141-D143 VanDerWaalsContact C-N 3.31Å; A141-K144 WeakPolarHBondContact CA-O 3.44Å; A141-K145 WeakPolarHBondContact O-CG 3.28Å; A141-V157 HydrophobicContact CB-CG1 3.99Å; A141-E159 VanDerWaalsContact CB-CA 3.43Å; A141-E159 HydrophobicContact CB-CB 3.87Å; A141-E159 HydrophobicContact CB-CG 4.32Å
142	A	87.8	Confident	90.4	Very high	68 Å²	68	72.6 Å²	72.6	56%	0.562	42%	0.422	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.3	-40.7	172.3	0	0	0	0	0	111	T140	T140-A142 PolarHBondContact O-N 3.3Å; T140-A142 VanDerWaalsContact O-N 3.15Å; T140-A142 WeakPolarHBondContact OG1-CB 3.5Å; T140-A142 PolarHBondContact OG1-N 3Å
143	D	89.3	Confident	91.1	Very high	122 Å²	122	71.1 Å²	71.1	65%	0.652	42%	0.416	S	S	*	.	T	Hydrogen-bonded Turn	trans	-88	-33.9	-177.5	-48.7	-57.8	0	0	0	111.7	V139 T140 A141	V139-D143 HydrophobicContact CG1-CB 4.09Å; T140-D143 PolarHBondContact O-N 3.03Å; T140-D143 PolarHBondContact OG1-OD2 2.71Å; A141-D143 VanDerWaalsContact C-N 3.31Å
144	K	90.5	Very high	91.7	Very high	75 Å²	75	74.5 Å²	74.5	33%	0.326	44%	0.439	S	S	.	.			trans	-130.6	97.9	-176.5	-170.9	172.9	179.5	177.1	0	112.1	V139 T140 A141 T146 V157 E174	V139-K144 HydrophobicContact CG1-CB 3.7Å; V139-K144 HydrophobicContact CG1-CD 4.42Å; T140-K144 PolarHBondContact O-N 3.44Å; A141-K144 WeakPolarHBondContact CA-O 3.44Å; K144-T146 WeakPolarHBondContact CG-O 3.1Å; K144-V157 WeakPolarHBondContact O-CB 3.47Å; K144-E174 WeakPolarHBondContact CD-OE1 3.15Å; K144-E174 WeakPolarHBondContact CE-OE1 3.33Å; K144-E174 IonicContact NZ-OE1 2.68Å; K144-E174 PolarHBondContact NZ-OE1 3.24Å; K144-E174 IonicContact NZ-OE2 3.81Å
145	K	94.5	Very high	92.2	Very high	148 Å²	148	74.2 Å²	74.2	64%	0.643	43%	0.434	S	S	*	.			trans	-88	-15.1	-176.7	-64.9	-179.6	-178.8	179.5	0	114.8	A141 T156 V157	A141-K145 WeakPolarHBondContact O-CG 3.28Å; K145-T156 WeakPolarHBondContact O-CA 3.11Å; K145-V157 PolarHBondContact O-N 3.23Å
146	T	95.4	Very high	92.7	Very high	80 Å²	80	75.5 Å²	75.5	49%	0.491	45%	0.446	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-133.8	150.1	-176.4	59.4	0	0	0	0	111.3	K144 T154 V155	K144-T146 WeakPolarHBondContact CG-O 3.1Å; T146-T154 HydrophobicContact CG2-CG2 4.47Å; T146-V155 CarbonylContact C-O 3.56Å; T146-V155 VanDerWaalsContact CA-O 3.27Å; T146-V155 WeakPolarHBondContact CA-O 3.26Å
147	A	94.5	Very high	93	Very high	32 Å²	32	74.8 Å²	74.8	26%	0.264	44%	0.44	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-141.2	168.3	173.5	0	0	0	0	0	109.5	T154 V155 V157	A147-T154 CarbonylContact O-C 3.54Å; A147-T154 WeakPolarHBondContact O-CA 2.89Å; A147-V155 HydrophobicContact CB-CG2 4.14Å; A147-V155 PolarHBondContact N-O 3.41Å; A147-V155 WeakPolarHBondContact O-CG2 2.93Å; A147-V155 PolarHBondContact O-N 3.43Å; A147-V157 HydrophobicContact CB-CG2 3.85Å
148	V	95.9	Very high	93.3	Very high	101 Å²	101	75.1 Å²	75.1	61%	0.612	44%	0.444	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-107.3	126.9	171.5	-178.4	0	0	0	0	107.2	G153	V148-G153 CarbonylContact C-O 3.6Å; V148-G153 WeakPolarHBondContact CA-O 3.42Å
149	D	94	Very high	93.4	Very high	65 Å²	65	78.1 Å²	78.1	35%	0.348	46%	0.461	S	S	.	.			trans	-77.2	178.7	178.7	80.1	-8.4	0	0	0	111.7	S151 G152 G153 V155	D149-S151 PolarHBondContact O-N 2.77Å; D149-S151 VanDerWaalsContact OD1-CA 3.31Å; D149-S151 WeakPolarHBondContact OD1-CA 3.39Å; D149-S151 WeakPolarHBondContact OD1-CB 2.94Å; D149-S151 PolarHBondContact OD1-N 3.26Å; D149-S151 PolarHBondContact OD1-OG 3.18Å; D149-S151 PolarHBondContact OD2-OG 3.08Å; D149-G152 PolarHBondContact O-N 3.09Å; D149-G152 VanDerWaalsContact O-N 3.1Å; D149-G152 PolarHBondContact OD1-N 3.28Å; D149-G153 PolarHBondContact N-O 2.88Å; D149-G153 PolarHBondContact OD1-N 3.2Å; D149-V155 HydrophobicContact CB-CG1 4.03Å; D149-V155 HydrophobicContact CB-CG2 4.36Å
150	M	92.6	Very high	93.4	Very high	178 Å²	178	81.9 Å²	81.9	88%	0.877	48%	0.476	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.2	-16.9	178.3	-61.7	-172.4	-62.7	0	0	113.6	L50 G152	L50-M150 HydrophobicContact CD2-CE 4.33Å; M150-G152 VanDerWaalsContact C-N 3.34Å
151	S	96.3	Very high	93.3	Very high	100 Å²	100	80.6 Å²	80.6	70%	0.699	47%	0.469	S	S	*	.	T	Hydrogen-bonded Turn	trans	-86.8	-6.5	175.6	79.5	0	0	0	0	112.9	D149	D149-S151 PolarHBondContact O-N 2.77Å; D149-S151 VanDerWaalsContact OD1-CA 3.31Å; D149-S151 WeakPolarHBondContact OD1-CA 3.39Å; D149-S151 WeakPolarHBondContact OD1-CB 2.94Å; D149-S151 PolarHBondContact OD1-N 3.26Å; D149-S151 PolarHBondContact OD1-OG 3.18Å; D149-S151 PolarHBondContact OD2-OG 3.08Å
152	G	95.6	Very high	93.3	Very high	54 Å²	54	83.4 Å²	83.4	56%	0.557	49%	0.486	S	S	*	.	S	Bend	trans	86.9	4.5	-176.2	0	0	0	0	0	113.9	D149 M150	D149-G152 PolarHBondContact O-N 3.09Å; D149-G152 VanDerWaalsContact O-N 3.1Å; D149-G152 PolarHBondContact OD1-N 3.28Å; M150-G152 VanDerWaalsContact C-N 3.34Å
153	G	97.4	Very high	93.3	Very high	28 Å²	28	81.1 Å²	81.1	29%	0.289	47%	0.465	S	S	.	.			trans	-77.5	142	176.7	0	0	0	0	0	112.1	V148 D149	V148-G153 CarbonylContact C-O 3.6Å; V148-G153 WeakPolarHBondContact CA-O 3.42Å; D149-G153 PolarHBondContact N-O 2.88Å; D149-G153 PolarHBondContact OD1-N 3.2Å
154	T	97	Very high	93.1	Very high	113 Å²	113	79.2 Å²	79.2	69%	0.693	46%	0.461	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-77.8	123.4	171.7	-59.1	0	0	0	0	109.5	T146 A147	T146-T154 HydrophobicContact CG2-CG2 4.47Å; A147-T154 CarbonylContact O-C 3.54Å; A147-T154 WeakPolarHBondContact O-CA 2.89Å
155	V	95.7	Very high	92.9	Very high	60 Å²	60	81.6 Å²	81.6	36%	0.364	47%	0.472	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-121.5	152.9	-179	-62.1	0	0	0	0	110.9	T146 A147 D149	T146-V155 CarbonylContact C-O 3.56Å; T146-V155 VanDerWaalsContact CA-O 3.27Å; T146-V155 WeakPolarHBondContact CA-O 3.26Å; A147-V155 HydrophobicContact CB-CG2 4.14Å; A147-V155 PolarHBondContact N-O 3.41Å; A147-V155 WeakPolarHBondContact O-CG2 2.93Å; A147-V155 PolarHBondContact O-N 3.43Å; D149-V155 HydrophobicContact CB-CG1 4.03Å; D149-V155 HydrophobicContact CB-CG2 4.36Å
156	T	95.4	Very high	92.5	Very high	113 Å²	113	76.3 Å²	76.3	69%	0.693	46%	0.459	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-86.3	134.5	175.9	50.9	0	0	0	0	110.8	K145	K145-T156 WeakPolarHBondContact O-CA 3.11Å
157	V	94.5	Very high	92.3	Very high	24 Å²	24	78.7 Å²	78.7	15%	0.145	46%	0.464	C	S	.	.	P	Polyproline II helix	trans	-85.8	129.8	176	176.9	0	0	0	0	109.2	A141 K144 K145 A147 F172	A141-V157 HydrophobicContact CB-CG1 3.99Å; K144-V157 WeakPolarHBondContact O-CB 3.47Å; K145-V157 PolarHBondContact O-N 3.23Å; A147-V157 HydrophobicContact CB-CG2 3.85Å; V157-F172 HydrophobicContact CG1-CD2 4.44Å; V157-F172 HydrophobicContact CG1-CE2 3.32Å; V157-F172 HydrophobicContact CG1-CZ 3.59Å
158	L	92.1	Very high	92	Very high	95 Å²	95	80 Å²	80	50%	0.497	47%	0.467	S	S	.	.	P	Polyproline II helix	trans	-86.8	139.2	178.4	-60.7	178.6	0	0	0	110.3	K160 Q170	L158-K160 VanDerWaalsContact C-N 3.33Å; L158-Q170 PolarHBondContact O-OE1 3.13Å
159	E	90.9	Very high	91.8	Very high	126 Å²	126	81.1 Å²	81.1	59%	0.589	46%	0.464	S	S	*	.	S	Bend	trans	-70.2	-35.8	173.6	-169.2	-171.1	153.9	0	0	111.7	A141 Q170	A141-E159 VanDerWaalsContact CB-CA 3.43Å; A141-E159 HydrophobicContact CB-CB 3.87Å; A141-E159 HydrophobicContact CB-CG 4.32Å; E159-Q170 PolarHBondContact O-N 3.35Å
160	K	90.9	Very high	91.6	Very high	89 Å²	89	80.6 Å²	80.6	39%	0.387	46%	0.459	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-133	135.1	179.4	-61.2	178.8	-172.9	173	0	110.3	L158 Q167 L168 K169	L158-K160 VanDerWaalsContact C-N 3.33Å; K160-Q167 HydrophobicContact CB-CB 4.26Å; K160-Q167 HydrophobicContact CD-CB 4.29Å; K160-L168 CarbonylContact C-O 3.58Å; K160-L168 WeakPolarHBondContact CA-O 3.37Å; K160-K169 HydrophobicContact CG-CG 4.47Å
161	V	89.8	Confident	91.5	Very high	14 Å²	14	75.4 Å²	75.4	9%	0.085	43%	0.43	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-90.9	122.5	174.2	-178.8	0	0	0	0	107.8	F54 I58 V163 Q167 L168 Q170	F54-V161 HydrophobicContact CE1-CG1 3.81Å; F54-V161 HydrophobicContact CZ-CG1 4.29Å; I58-V161 HydrophobicContact CD1-CG1 4.07Å; V161-V163 HydrophobicContact CG1-CG1 4.49Å; V161-Q167 CarbonylContact O-C 3.6Å; V161-Q167 WeakPolarHBondContact O-CA 3.33Å; V161-L168 PolarHBondContact N-O 2.92Å; V161-L168 PolarHBondContact O-N 2.99Å; V161-Q170 HydrophobicContact CG2-CB 4.22Å; V161-Q170 HydrophobicContact CG2-CG 4.49Å
162	P	89.5	Confident	91.2	Very high	67 Å²	67	73.5 Å²	73.5	44%	0.435	41%	0.409	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-66.4	139	172.6	30.1	-33.3	0	0	0	109.5
163	V	87.9	Confident	90.9	Very high	20 Å²	20	73.6 Å²	73.6	12%	0.121	39%	0.393	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-138	160.4	175	-61.7	0	0	0	0	109.2	I58 L62 V161 K165 G166 L168	I58-V163 HydrophobicContact CG2-CB 4.33Å; I58-V163 HydrophobicContact CG2-CG1 3.52Å; L62-V163 HydrophobicContact CD1-CB 3.71Å; L62-V163 HydrophobicContact CD1-CG1 3.98Å; L62-V163 HydrophobicContact CD1-CG2 3.93Å; V161-V163 HydrophobicContact CG1-CG1 4.49Å; V163-K165 PolarHBondContact O-N 3.18Å; V163-K165 VanDerWaalsContact O-N 3.11Å; V163-G166 PolarHBondContact N-O 2.82Å; V163-G166 CarbonylContact O-C 3.43Å; V163-G166 PolarHBondContact O-N 3.33Å; V163-L168 HydrophobicContact CG1-CD1 3.81Å; V163-L168 HydrophobicContact CG1-CG 3.94Å; V163-L168 HydrophobicContact CG2-CG 4Å
164	S	85.4	Confident	90.5	Very high	81 Å²	81	73.9 Å²	73.9	57%	0.566	39%	0.387	S	S	*	.	T	Hydrogen-bonded Turn	trans	-52	-37.9	179.8	58.6	0	0	0	0	112.8
165	K	84.5	Confident	90.1	Very high	126 Å²	126	71.4 Å²	71.4	55%	0.548	37%	0.372	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89.8	10	179.4	-60.9	-177.1	-177.3	178.5	0	114.6	L62 D63 V163	L62-K165 PolarHBondContact O-NZ 3.13Å; D63-K165 IonicContact OD1-NZ 2.66Å; V163-K165 PolarHBondContact O-N 3.18Å; V163-K165 VanDerWaalsContact O-N 3.11Å
166	G	87.9	Confident	89.7	Confident	37 Å²	37	73.2 Å²	73.2	38%	0.381	38%	0.375	S	S	.	.	E	Extended strand (participates in β ladder)	trans	134.4	-124.4	176.9	0	0	0	0	0	114.3	V163	V163-G166 PolarHBondContact N-O 2.82Å; V163-G166 CarbonylContact O-C 3.43Å; V163-G166 PolarHBondContact O-N 3.33Å
167	Q	90.1	Very high	89.3	Confident	129 Å²	129	72.7 Å²	72.7	60%	0.603	38%	0.375	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-138.9	133.3	-178.8	-68.9	-173.9	-31.8	0	0	110.5	K160 V161	K160-Q167 HydrophobicContact CB-CB 4.26Å; K160-Q167 HydrophobicContact CD-CB 4.29Å; V161-Q167 CarbonylContact O-C 3.6Å; V161-Q167 WeakPolarHBondContact O-CA 3.33Å
168	L	89.1	Confident	89	Confident	59 Å²	59	73.8 Å²	73.8	31%	0.309	38%	0.38	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-102.2	139.6	174.5	-62.9	-179.5	0	0	0	110.3	L87 K160 V161 V163	L87-L168 HydrophobicContact CD2-CD1 4.06Å; K160-L168 CarbonylContact C-O 3.58Å; K160-L168 WeakPolarHBondContact CA-O 3.37Å; V161-L168 PolarHBondContact N-O 2.92Å; V161-L168 PolarHBondContact O-N 2.99Å; V163-L168 HydrophobicContact CG1-CD1 3.81Å; V163-L168 HydrophobicContact CG1-CG 3.94Å; V163-L168 HydrophobicContact CG2-CG 4Å
169	K	90.4	Very high	88.5	Confident	126 Å²	126	74.7 Å²	74.7	55%	0.548	39%	0.391	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-76	133.8	172.1	-70	-175.7	-178	179.2	0	109.6	K160 Y171	K160-K169 HydrophobicContact CG-CG 4.47Å; K169-Y171 HydrophobicContact CB-CD2 4.33Å; K169-Y171 HydrophobicContact CB-CE2 3.54Å; K169-Y171 HydrophobicContact CD-CE2 4.39Å; K169-Y171 WeakPolarHBondContact CD-OH 3.15Å
170	Q	90.1	Very high	87.9	Confident	54 Å²	54	76.5 Å²	76.5	25%	0.252	40%	0.402	S	S	.	.	P	Polyproline II helix	trans	-94.5	131.6	177.6	-166.5	172.1	31.5	0	0	110.8	L158 E159 V161 F172	L158-Q170 PolarHBondContact O-OE1 3.13Å; E159-Q170 PolarHBondContact O-N 3.35Å; V161-Q170 HydrophobicContact CG2-CB 4.22Å; V161-Q170 HydrophobicContact CG2-CG 4.49Å; Q170-F172 VanDerWaalsContact CD-CZ 3.41Å; Q170-F172 HydrophobicContact CG-CE2 3.85Å; Q170-F172 HydrophobicContact CG-CZ 3.86Å
171	Y	89.9	Confident	86.9	Confident	68 Å²	68	74 Å²	74	27%	0.267	40%	0.401	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-128.1	144.4	174.6	-62	-86.2	0	0	0	109.3	V91 T140 K169	V91-Y171 HydrophobicContact CG1-CE1 4.45Å; T140-Y171 HydrophobicContact CG2-CD1 3.69Å; T140-Y171 HydrophobicContact CG2-CE1 3.66Å; K169-Y171 HydrophobicContact CB-CD2 4.33Å; K169-Y171 HydrophobicContact CB-CE2 3.54Å; K169-Y171 HydrophobicContact CD-CE2 4.39Å; K169-Y171 WeakPolarHBondContact CD-OH 3.15Å
172	F	90.6	Very high	85.8	Confident	60 Å²	60	80.9 Å²	80.9	26%	0.263	43%	0.427	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-114.1	127.1	174.1	-60.9	-89.1	0	0	0	108.8	W138 V139 V157 Q170 E174	W138-F172 CarbonylContact C-O 3.59Å; W138-F172 WeakPolarHBondContact CA-O 3.35Å; V139-F172 HydrophobicContact CB-CB 4.34Å; V139-F172 PolarHBondContact N-O 3.41Å; V139-F172 PolarHBondContact O-N 3.09Å; V157-F172 HydrophobicContact CG1-CD2 4.44Å; V157-F172 HydrophobicContact CG1-CE2 3.32Å; V157-F172 HydrophobicContact CG1-CZ 3.59Å; Q170-F172 VanDerWaalsContact CD-CZ 3.41Å; Q170-F172 HydrophobicContact CG-CE2 3.85Å; Q170-F172 HydrophobicContact CG-CZ 3.86Å; F172-E174 HydrophobicContact CB-CG 4.24Å; F172-E174 PolarHBondContact O-N 2.66Å
173	Y	88.9	Confident	84.7	Confident	56 Å²	56	80.2 Å²	80.2	22%	0.22	42%	0.422	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-90	105.2	169.4	-176.9	-117.1	0	0	0	109	P95 P96 L98 S136 W138	P95-Y173 HydrophobicContact CB-CD2 4.29Å; P95-Y173 HydrophobicContact CB-CE1 4.36Å; P95-Y173 HydrophobicContact CB-CE2 3.23Å; P95-Y173 WeakPolarHBondContact CB-OH 3.28Å; P96-Y173 VanDerWaalsContact CD-CD1 3.47Å; P96-Y173 VanDerWaalsContact CD-CD2 3.46Å; P96-Y173 HydrophobicContact CG-CD1 3.52Å; P96-Y173 HydrophobicContact CG-CD2 4.33Å; P96-Y173 HydrophobicContact CG-CE1 3.91Å; P96-Y173 HydrophobicContact CG-CG 3.73Å; L98-Y173 HydrophobicContact CD2-CE1 3.76Å; L98-Y173 HydrophobicContact CG-CE1 4.45Å; S136-Y173 WeakPolarHBondContact CB-OH 2.87Å; S136-Y173 PolarHBondContact OG-OH 2.98Å; W138-Y173 HydrophobicContact CD2-CD2 4.12Å; W138-Y173 HydrophobicContact CE3-CD2 4.46Å; W138-Y173 HydrophobicContact CZ2-CD2 4.37Å
174	E	89.4	Confident	83.7	Confident	35 Å²	35	89.4 Å²	89.4	16%	0.164	46%	0.46	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-105.6	133.9	-177.9	-65	-165.4	-176.5	0	0	110.5	S136 E137 V139 K144 F172 K176	S136-E174 CarbonylContact C-O 3.59Å; S136-E174 VanDerWaalsContact CA-O 3.22Å; S136-E174 WeakPolarHBondContact CA-O 3.38Å; E137-E174 PolarHBondContact N-O 3.46Å; E137-E174 PolarHBondContact O-N 3.31Å; V139-E174 HydrophobicContact CB-CG 4.41Å; V139-E174 HydrophobicContact CG2-CB 4.02Å; V139-E174 HydrophobicContact CG2-CG 3.88Å; K144-E174 WeakPolarHBondContact CD-OE1 3.15Å; K144-E174 WeakPolarHBondContact CE-OE1 3.33Å; K144-E174 IonicContact NZ-OE1 2.68Å; K144-E174 PolarHBondContact NZ-OE1 3.24Å; K144-E174 IonicContact NZ-OE2 3.81Å; F172-E174 HydrophobicContact CB-CG 4.24Å; F172-E174 PolarHBondContact O-N 2.66Å; E174-K176 WeakPolarHBondContact OE2-CE 3.21Å; E174-K176 IonicContact OE2-NZ 2.72Å; E174-K176 PolarHBondContact OE2-NZ 3.31Å
175	T	87.9	Confident	83.3	Confident	61 Å²	61	94.6 Å²	94.6	37%	0.374	48%	0.475	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-116.3	126.6	171.5	-61.2	0	0	0	0	109	I135 S136	I135-T175 WeakPolarHBondContact O-CA 3.22Å; S136-T175 WeakPolarHBondContact CB-OG1 3.32Å; S136-T175 WeakPolarHBondContact OG-CB 3.4Å; S136-T175 VanDerWaalsContact OG-CG2 3.29Å; S136-T175 WeakPolarHBondContact OG-CG2 3.4Å; S136-T175 PolarHBondContact OG-OG1 2.9Å
176	K	88.4	Confident	82.8	Confident	97 Å²	97	90.8 Å²	90.8	42%	0.422	47%	0.472	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-122.6	153.2	-178.1	-65	168	-173.4	156.9	0	109.5	S134 I135 E137 E174 N178	S134-K176 CarbonylContact C-O 3.54Å; S134-K176 VanDerWaalsContact CA-O 3.23Å; S134-K176 WeakPolarHBondContact CA-O 3.36Å; S134-K176 WeakPolarHBondContact CB-O 3.5Å; I135-K176 PolarHBondContact N-O 2.89Å; I135-K176 PolarHBondContact O-N 3.32Å; E137-K176 IonicContact OE1-NZ 3.69Å; E137-K176 PolarHBondContact OE1-NZ 3.04Å; E174-K176 WeakPolarHBondContact OE2-CE 3.21Å; E174-K176 IonicContact OE2-NZ 2.72Å; E174-K176 PolarHBondContact OE2-NZ 3.31Å; K176-N178 PolarHBondContact O-N 2.75Å
177	C	87.8	Confident	82.5	Confident	103 Å²	103	91.7 Å²	91.7	70%	0.696	47%	0.472	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-63.3	137.1	171.2	-61.5	0	0	0	0	109.9	P179	C177-P179 WeakPolarHBondContact O-CD 3.38Å
178	N	86.4	Confident	82	Confident	46 Å²	46	91.4 Å²	91.4	25%	0.246	47%	0.465	C	S	.	.			trans	-66.6	117.7	172.9	-177.9	-10.4	0	0	0	108.9	D133 I135 K176 M180 G181	D133-N178 HydrophobicContact CB-CB 3.69Å; D133-N178 WeakPolarHBondContact O-CB 3.48Å; D133-N178 PolarHBondContact O-N 3.01Å; I135-N178 HydrophobicContact CD1-CB 4.09Å; I135-N178 HydrophobicContact CG1-CB 4.02Å; K176-N178 PolarHBondContact O-N 2.75Å; N178-M180 PolarHBondContact O-N 2.85Å; N178-M180 WeakPolarHBondContact OD1-CB 3.44Å; N178-M180 PolarHBondContact OD1-N 3.29Å; N178-G181 PolarHBondContact O-N 3.23Å
179	P	81.9	Confident	81.6	Confident	114 Å²	114	93 Å²	93	74%	0.74	47%	0.473	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.8	-21.9	-175.8	28.3	-36.1	0	0	0	113.1	C177 G181	C177-P179 WeakPolarHBondContact O-CD 3.38Å; P179-G181 VanDerWaalsContact C-N 3.26Å; P179-G181 PolarHBondContact O-N 2.93Å
180	M	78.7	Confident	81.1	Confident	164 Å²	164	91.3 Å²	91.3	81%	0.808	47%	0.469	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.5	-25.4	179.2	-68.4	-64.7	167.6	0	0	112	N178	N178-M180 PolarHBondContact O-N 2.85Å; N178-M180 WeakPolarHBondContact OD1-CB 3.44Å; N178-M180 PolarHBondContact OD1-N 3.29Å
181	G	69.9	Low	80.6	Confident	37 Å²	37	93.3 Å²	93.3	38%	0.381	48%	0.481	S	S	.	.			trans	54.5	170.3	-177.4	0	0	0	0	0	113.5	N178 P179	N178-G181 PolarHBondContact O-N 3.23Å; P179-G181 VanDerWaalsContact C-N 3.26Å; P179-G181 PolarHBondContact O-N 2.93Å
182	Y	67.1	Low	80.1	Confident	159 Å²	159	94.8 Å²	94.8	62%	0.624	49%	0.494	S	S	*	.	S	Bend	trans	-98.3	-28.6	171.9	-165.8	-99.3	0	0	0	112.3	R188	Y182-R188 VanDerWaalsContact CD1-NH1 3.35Å
183	T	65.9	Low	79.4	Confident	53 Å²	53	97 Å²	97	33%	0.325	51%	0.508	S	S	.	.			trans	-134.5	153	-178	90.9	0	0	0	0	111.8	E185 G186	T183-E185 VanDerWaalsContact C-N 3.31Å; T183-E185 PolarHBondContact OG1-N 3.22Å; T183-G186 PolarHBondContact OG1-N 2.86Å; T183-G186 PolarHBondContact OG1-O 3.03Å
184	K	68.3	Low	78.8	Confident	213 Å²	213	99.7 Å²	99.7	93%	0.926	53%	0.527	S	S	*	.	S	Bend	trans	-82.4	-13	175.6	-59.9	-178.6	-178.9	177.3	0	112.7
185	E	76.8	Confident	78.1	Confident	189 Å²	189	104.4 Å²	104.4	88%	0.883	55%	0.553	S	S	*	*	S	Bend	trans	-103.1	-1.9	-170.7	-54.8	-68.1	158.9	0	0	112.7	T183	T183-E185 VanDerWaalsContact C-N 3.31Å; T183-E185 PolarHBondContact OG1-N 3.22Å
186	G	73.8	Confident	77.3	Confident	47 Å²	47	107.7 Å²	107.7	49%	0.485	57%	0.567	S	S	.	*	S	Bend	trans	138.6	-149.2	177.8	0	0	0	0	0	113.3	T183	T183-G186 PolarHBondContact OG1-N 2.86Å; T183-G186 PolarHBondContact OG1-O 3.03Å
187	C	81.5	Confident	76.4	Confident	56 Å²	56	108.6 Å²	108.6	38%	0.378	58%	0.579	S	S	.	*			trans	-66.1	161.8	171.7	-56.6	0	0	0	0	111.2	V131 C132	V131-C187 HydrophobicContact CG1-CB 3.36Å; C132-C187 PolarHBondContact SG-SG 2.98Å
188	R	78.4	Confident	75.3	Confident	122 Å²	122	109.1 Å²	109.1	46%	0.46	57%	0.569	S	S	.	*			trans	-55.3	0	176.4	-177.7	-174.6	-63.6	-81.6	-4	112.4	V131 Y182	V131-R188 PolarHBondContact O-N 3.39Å; Y182-R188 VanDerWaalsContact CD1-NH1 3.35Å

Retrieved 188 of 188 residues in 232.6 ms (Link to these results)

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