S29A3_MOUSE Loading...

Equilibrative nucleoside transporter 3

Uniporter that mediates the facilitative transport of nucleoside across lysosomal and mitochondrial membranes^1,2. Functions as a non-electrogenic Na(+)-independent transporter³. Substrate transport is pH-dependent and enhanced under acidic condition, probably reflecting the location of the transporter in acidic intracellular compartments⁴. Proton is not a cotransporting ion but most likely change the ionization state of the transporter which dictates transport-permissible/impermissible conformation for nucleoside translocation (By similarity). May direct the nucleoside transport from lysosomes to cytosol or cytosol to mitochondria to facilitate the fundamental function of salvage synthesis of nucleic acids⁵. Involved in the transport of nucleosides (adenosine, guanosine, uridine, thymidine, cytidine and inosine) and deoxynucleosides (deoxyadenosine, deoxycytidine)^6,7. Also mediates transport of purine nucleobases (adenine, guanine), and pyrimidine nucleobases (uracil)⁸. Also able to transport monoamine neurotransmitters dopamine, serotonin, noradrenaline and tyramine (By similarity). Capable of transporting ATP (By similarity). Mediates nucleoside export from lysosomes in macrophages, which regulates macrophage functions and numbers⁹.

AlphaFold DB , UniProt , Accession Q99P65, Species MOUSE (Mus musculus, Mouse), Gene Slc29a3, Length 475 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	32.9	Very low	33.7	Very low	232 Å²	232	107.6 Å²	107.6	100%	1.143	59%	0.593	S	S	*	*				0	104.6	0	-117.4	171.1	-168.2	0	0	106.8	F3	M1-F3 PolarHBondContact O-N 2.8Å
2	A	30.4	Very low	33.6	Very low	110 Å²	110	104.5 Å²	104.5	91%	0.909	58%	0.584	S	S	*	*			trans	-68.1	111.6	-176.5	0	0	0	0	0	109.1	A4	A2-A4 PolarHBondContact O-N 3.49Å
3	F	33.4	Very low	33.6	Very low	166 Å²	166	99.5 Å²	99.5	73%	0.728	56%	0.56	S	S	*	*	P	Polyproline II helix	trans	-67	120.6	171.3	-77.4	-88.1	0	0	0	108	M1	M1-F3 PolarHBondContact O-N 2.8Å
4	A	30.3	Very low	33.6	Very low	68 Å²	68	100.4 Å²	100.4	56%	0.562	56%	0.563	S	S	*	*	P	Polyproline II helix	trans	-56.7	139.4	170.1	0	0	0	0	0	109.5	A2	A2-A4 PolarHBondContact O-N 3.49Å
5	S	34.2	Very low	33.5	Very low	60 Å²	60	97.9 Å²	97.9	42%	0.42	56%	0.56	S	S	.	*	P	Polyproline II helix	trans	-56.2	145.1	-178	70.9	0	0	0	0	111.3	D7 N8	S5-D7 PolarHBondContact O-N 3.3Å; S5-N8 PolarHBondContact O-N 3.35Å
6	E	40.7	Very low	33.8	Very low	49 Å²	49	98.3 Å²	98.3	23%	0.229	57%	0.565	C	S	.	*	H	α-helix	trans	-51.8	-32.7	-179.4	-74.6	-168.7	133.6	0	0	111.8	N8 V9 Y10 R196	E6-N8 PolarHBondContact O-N 2.87Å; E6-V9 PolarHBondContact O-N 2.81Å; E6-Y10 HydrophobicContact CB-CD2 4.49Å; E6-Y10 WeakPolarHBondContact O-CB 3Å; E6-Y10 WeakPolarHBondContact O-CD2 3.3Å; E6-Y10 PolarHBondContact O-N 3.37Å; E6-R196 IonicContact OE1-NH1 3.95Å
7	D	36.2	Very low	34.1	Very low	110 Å²	110	98.2 Å²	98.2	59%	0.588	55%	0.554	S	S	*	*	H	α-helix	trans	-61.8	-37.1	176.6	-72	-25	0	0	0	113.6	S5 H11	S5-D7 PolarHBondContact O-N 3.3Å; D7-H11 VanDerWaalsContact O-CB 3.26Å; D7-H11 WeakPolarHBondContact O-CB 2.97Å; D7-H11 PolarHBondContact O-N 3.15Å
8	N	32	Very low	33.9	Very low	106 Å²	106	104.6 Å²	104.6	57%	0.567	57%	0.568	S	S	*	*	H	α-helix	trans	-74.1	-34.2	179.5	-87.7	-20.4	0	0	0	112.3	S5 E6 S12	S5-N8 PolarHBondContact O-N 3.35Å; E6-N8 PolarHBondContact O-N 2.87Å; N8-S12 WeakPolarHBondContact O-CB 3.45Å; N8-S12 PolarHBondContact O-N 2.99Å
9	V	36	Very low	33.9	Very low	77 Å²	77	103.4 Å²	103.4	47%	0.467	57%	0.574	S	S	.	*	H	α-helix	trans	-74.9	-37.5	176.2	-178.5	0	0	0	0	110.7	E6 S13	E6-V9 PolarHBondContact O-N 2.81Å; V9-S13 VanDerWaalsContact O-CB 3.28Å; V9-S13 WeakPolarHBondContact O-CB 3.5Å; V9-S13 PolarHBondContact O-N 3.01Å; V9-S13 PolarHBondContact O-OG 3.49Å
10	Y	33.9	Very low	33.7	Very low	68 Å²	68	104.5 Å²	104.5	27%	0.267	59%	0.585	S	S	.	*	H	α-helix	trans	-68.3	-44.5	174	-96.5	-76.7	0	0	0	112.9	E6 S13 N14 R45 P194	E6-Y10 HydrophobicContact CB-CD2 4.49Å; E6-Y10 WeakPolarHBondContact O-CB 3Å; E6-Y10 WeakPolarHBondContact O-CD2 3.3Å; E6-Y10 PolarHBondContact O-N 3.37Å; Y10-S13 PolarHBondContact O-N 3.34Å; Y10-N14 WeakPolarHBondContact O-CB 2.8Å; Y10-N14 PolarHBondContact O-N 3.12Å; Y10-R45 PolarHBondContact OH-NH2 3.34Å; Y10-P194 WeakPolarHBondContact OH-CB 3.29Å; Y10-P194 WeakPolarHBondContact OH-CG 3.46Å
11	H	31.2	Very low	33.7	Very low	138 Å²	138	104.1 Å²	104.1	64%	0.639	59%	0.59	S	S	*	*	H	α-helix	trans	-65.4	-41	174.7	-98.4	-69	0	0	0	111.6	D7 A15	D7-H11 VanDerWaalsContact O-CB 3.26Å; D7-H11 WeakPolarHBondContact O-CB 2.97Å; D7-H11 PolarHBondContact O-N 3.15Å; H11-A15 WeakPolarHBondContact O-CA 3.32Å; H11-A15 WeakPolarHBondContact O-CB 3.22Å; H11-A15 PolarHBondContact O-N 2.85Å
12	S	32	Very low	33.8	Very low	70 Å²	70	99.3 Å²	99.3	49%	0.49	57%	0.569	S	S	.	*	H	α-helix	trans	-64.9	-43.1	176.3	-176.9	0	0	0	0	111.8	N8 V16	N8-S12 WeakPolarHBondContact O-CB 3.45Å; N8-S12 PolarHBondContact O-N 2.99Å; S12-V16 WeakPolarHBondContact O-CB 3.45Å; S12-V16 WeakPolarHBondContact O-CG2 3.09Å; S12-V16 PolarHBondContact O-N 3.03Å; S12-V16 VanDerWaalsContact O-N 3.12Å
13	S	33.3	Very low	34.3	Very low	39 Å²	39	101.9 Å²	101.9	27%	0.273	56%	0.561	S	S	.	*	H	α-helix	trans	-66.2	-44.2	179.8	-57	0	0	0	0	110.7	V9 Y10 Y17	V9-S13 VanDerWaalsContact O-CB 3.28Å; V9-S13 WeakPolarHBondContact O-CB 3.5Å; V9-S13 PolarHBondContact O-N 3.01Å; V9-S13 PolarHBondContact O-OG 3.49Å; Y10-S13 PolarHBondContact O-N 3.34Å; S13-Y17 WeakPolarHBondContact O-CD2 3.39Å; S13-Y17 WeakPolarHBondContact O-CE2 3.36Å
14	N	33.5	Very low	34.7	Very low	112 Å²	112	101.8 Å²	101.8	60%	0.599	56%	0.563	S	S	*	*	H	α-helix	trans	-76.6	-28.6	178.5	-77.9	-17	0	0	0	114.1	Y10	Y10-N14 WeakPolarHBondContact O-CB 2.8Å; Y10-N14 PolarHBondContact O-N 3.12Å
15	A	33.3	Very low	35	Very low	63 Å²	63	106 Å²	106	52%	0.521	57%	0.571	S	S	.	*	H	α-helix	trans	-75.6	-31.6	178.7	0	0	0	0	0	112.6	H11 Y17 R18	H11-A15 WeakPolarHBondContact O-CA 3.32Å; H11-A15 WeakPolarHBondContact O-CB 3.22Å; H11-A15 PolarHBondContact O-N 2.85Å; A15-Y17 PolarHBondContact O-N 3.49Å; A15-R18 PolarHBondContact O-N 3.24Å
16	V	38.3	Very low	35.2	Very low	105 Å²	105	105.5 Å²	105.5	64%	0.636	57%	0.571	S	S	*	*	T	Hydrogen-bonded Turn	trans	-67.8	-15.5	177.7	170.5	0	0	0	0	112.6	S12	S12-V16 WeakPolarHBondContact O-CB 3.45Å; S12-V16 WeakPolarHBondContact O-CG2 3.09Å; S12-V16 PolarHBondContact O-N 3.03Å; S12-V16 VanDerWaalsContact O-N 3.12Å
17	Y	38.4	Very low	35.1	Very low	97 Å²	97	107 Å²	107	38%	0.38	58%	0.581	S	S	.	*	T	Hydrogen-bonded Turn	trans	-96	8.5	178.8	-59	-56.1	0	0	0	115.3	S13 A15 A19 Q370 G373	S13-Y17 WeakPolarHBondContact O-CD2 3.39Å; S13-Y17 WeakPolarHBondContact O-CE2 3.36Å; A15-Y17 PolarHBondContact O-N 3.49Å; Y17-A19 PolarHBondContact O-N 2.86Å; Y17-Q370 PolarHBondContact OH-O 3.07Å; Y17-G373 VanDerWaalsContact CE1-CA 3.45Å
18	R	29.4	Very low	35	Very low	213 Å²	213	108.7 Å²	108.7	80%	0.804	59%	0.585	S	S	*	*			trans	-90.3	101.7	172.1	-100.9	-175.8	-152	155.5	10.7	110.9	A15	A15-R18 PolarHBondContact O-N 3.24Å
19	A	33.9	Very low	35.3	Very low	82 Å²	82	108.6 Å²	108.6	68%	0.678	58%	0.581	S	S	*	*			trans	-107.5	145.8	159.3	0	0	0	0	0	109.6	Y17 S21	Y17-A19 PolarHBondContact O-N 2.86Å; A19-S21 PolarHBondContact O-N 3.4Å
20	P	31.2	Very low	35.3	Very low	125 Å²	125	107 Å²	107	81%	0.812	58%	0.577	S	S	*	*			trans	-84.3	105.7	-172.8	32.5	-30	0	0	0	110.4
21	S	32.7	Very low	35.4	Very low	97 Å²	97	109.1 Å²	109.1	68%	0.678	59%	0.592	S	S	*	*			trans	-155.2	129.5	163.4	59.9	0	0	0	0	112.4	A19	A19-S21 PolarHBondContact O-N 3.4Å
22	N	36.2	Very low	35.6	Very low	130 Å²	130	107.3 Å²	107.3	70%	0.695	59%	0.586	S	S	*	*			trans	57.4	87	178.8	-69.2	2.5	0	0	0	116.3	Q24 A26	N22-Q24 PolarHBondContact O-N 3.12Å; N22-A26 PolarHBondContact O-N 2.85Å
23	H	41.1	Very low	35.8	Very low	164 Å²	164	105.6 Å²	105.6	76%	0.759	58%	0.579	S	S	*	*	T	Hydrogen-bonded Turn	trans	-55.7	16.4	177.9	-81.7	-63.9	0	0	0	117.3	D27	H23-D27 IonicContact ND1-OD2 3.9Å
24	Q	39.9	Very low	35.8	Very low	165 Å²	165	110.1 Å²	110.1	77%	0.771	59%	0.594	S	S	*	*	T	Hydrogen-bonded Turn	trans	-132.1	-48	-176.2	-141.8	162.7	-11.1	0	0	113.2	N22 Q28	N22-Q24 PolarHBondContact O-N 3.12Å; Q24-Q28 WeakPolarHBondContact O-CB 2.9Å; Q24-Q28 PolarHBondContact O-N 2.78Å
25	E	38.5	Very low	35.8	Very low	155 Å²	155	111 Å²	111	72%	0.724	60%	0.598	S	S	*	*	H	α-helix	trans	-77.8	-37.1	173.5	-77.5	-176.7	147.2	0	0	112.6	D27 Q28 E29	E25-D27 VanDerWaalsContact C-N 3.33Å; E25-Q28 PolarHBondContact O-N 2.95Å; E25-E29 PolarHBondContact O-N 3.48Å
26	A	38.3	Very low	36.2	Very low	50 Å²	50	112.6 Å²	112.6	41%	0.413	60%	0.597	S	S	.	*	H	α-helix	trans	-68.6	-33.9	176.6	0	0	0	0	0	111.8	N22 A30	N22-A26 PolarHBondContact O-N 2.85Å; A26-A30 WeakPolarHBondContact O-CB 3.41Å; A26-A30 PolarHBondContact O-N 3.29Å
27	D	36.8	Very low	36.2	Very low	81 Å²	81	114.2 Å²	114.2	43%	0.433	60%	0.603	S	S	.	*	H	α-helix	trans	-73.5	-28.1	176.6	-81.4	-37.2	0	0	0	112	H23 E25 L31	H23-D27 IonicContact ND1-OD2 3.9Å; E25-D27 VanDerWaalsContact C-N 3.33Å; D27-L31 VanDerWaalsContact O-CB 3.3Å; D27-L31 WeakPolarHBondContact O-CB 3.39Å; D27-L31 PolarHBondContact O-N 3.37Å
28	Q	35.7	Very low	35.9	Very low	145 Å²	145	118.7 Å²	118.7	68%	0.678	62%	0.62	S	S	*	*	H	α-helix	trans	-79.8	-40.8	176.5	-146	167.1	-1	0	0	112.3	Q24 E25 A30 L31 L32	Q24-Q28 WeakPolarHBondContact O-CB 2.9Å; Q24-Q28 PolarHBondContact O-N 2.78Å; E25-Q28 PolarHBondContact O-N 2.95Å; Q28-A30 VanDerWaalsContact C-N 3.32Å; Q28-L31 PolarHBondContact O-N 3.45Å; Q28-L32 WeakPolarHBondContact O-CB 3.45Å; Q28-L32 PolarHBondContact O-N 2.9Å
29	E	37.4	Very low	36.3	Very low	104 Å²	104	111.3 Å²	111.3	49%	0.486	60%	0.6	S	S	.	*	H	α-helix	trans	-63.9	-36.6	167.3	-85.3	-163.1	157.1	0	0	111.1	E25 G33 R375	E25-E29 PolarHBondContact O-N 3.48Å; E29-G33 PolarHBondContact O-N 2.95Å; E29-R375 IonicContact OE2-CZ 3.84Å; E29-R375 IonicContact OE2-NH1 3.76Å; E29-R375 IonicContact OE2-NH2 3.3Å; E29-R375 PolarHBondContact OE2-NH2 2.83Å; E29-R375 VanDerWaalsContact OE2-NH2 3.12Å
30	A	37.1	Very low	36.5	Very low	45 Å²	45	111.3 Å²	111.3	37%	0.372	60%	0.6	S	S	.	*	H	α-helix	trans	-74.9	-31.5	177.9	0	0	0	0	0	113.5	A26 Q28 K34	A26-A30 WeakPolarHBondContact O-CB 3.41Å; A26-A30 PolarHBondContact O-N 3.29Å; Q28-A30 VanDerWaalsContact C-N 3.32Å; A30-K34 WeakPolarHBondContact O-CB 3.16Å; A30-K34 VanDerWaalsContact O-CG 3.32Å; A30-K34 WeakPolarHBondContact O-CG 3.26Å; A30-K34 PolarHBondContact O-N 2.73Å
31	L	35.7	Very low	36.7	Very low	111 Å²	111	112.1 Å²	112.1	58%	0.581	61%	0.605	S	S	*	*	H	α-helix	trans	-70.3	-39.5	171.2	-121	119.1	0	0	0	111	D27 Q28 K34 L35	D27-L31 VanDerWaalsContact O-CB 3.3Å; D27-L31 WeakPolarHBondContact O-CB 3.39Å; D27-L31 PolarHBondContact O-N 3.37Å; Q28-L31 PolarHBondContact O-N 3.45Å; L31-K34 PolarHBondContact O-N 2.97Å; L31-L35 HydrophobicContact CD2-CD1 4.21Å; L31-L35 WeakPolarHBondContact O-CB 3.28Å; L31-L35 PolarHBondContact O-N 3.35Å
32	L	35.7	Very low	37.3	Very low	100 Å²	100	111 Å²	111	52%	0.524	61%	0.61	S	S	.	*	H	α-helix	trans	-69	-40.3	176.9	-162	71.5	0	0	0	111.2	Q28 L35 L36	Q28-L32 WeakPolarHBondContact O-CB 3.45Å; Q28-L32 PolarHBondContact O-N 2.9Å; L32-L35 PolarHBondContact O-N 2.93Å; L32-L36 HydrophobicContact CG-CD1 4.34Å; L32-L36 WeakPolarHBondContact O-CB 3.45Å; L32-L36 WeakPolarHBondContact O-CD1 3.17Å; L32-L36 WeakPolarHBondContact O-CG 3.48Å; L32-L36 PolarHBondContact O-N 3.42Å
33	G	34.6	Very low	38	Very low	34 Å²	34	109.7 Å²	109.7	35%	0.351	60%	0.602	S	S	.	*	H	α-helix	trans	-65.2	-39.8	171.2	0	0	0	0	0	113.1	E29 L36 D37	E29-G33 PolarHBondContact O-N 2.95Å; G33-L36 PolarHBondContact O-N 3.05Å; G33-D37 PolarHBondContact O-N 2.82Å
34	K	33.7	Very low	39	Very low	135 Å²	135	110.7 Å²	110.7	59%	0.587	61%	0.607	S	S	*	*	H	α-helix	trans	-65.8	-35.7	172.7	-85.6	-179.2	174.4	179.2	0	112.5	A30 L31 Y38	A30-K34 WeakPolarHBondContact O-CB 3.16Å; A30-K34 VanDerWaalsContact O-CG 3.32Å; A30-K34 WeakPolarHBondContact O-CG 3.26Å; A30-K34 PolarHBondContact O-N 2.73Å; L31-K34 PolarHBondContact O-N 2.97Å; K34-Y38 WeakPolarHBondContact O-CD2 3.41Å; K34-Y38 PolarHBondContact O-N 3.47Å
35	L	33.7	Very low	40.7	Very low	130 Å²	130	107.5 Å²	107.5	68%	0.681	59%	0.588	S	S	*	*	H	α-helix	trans	-73.5	-27.8	176.4	-110.6	105.7	0	0	0	113	L31 L32	L31-L35 HydrophobicContact CD2-CD1 4.21Å; L31-L35 WeakPolarHBondContact O-CB 3.28Å; L31-L35 PolarHBondContact O-N 3.35Å; L32-L35 PolarHBondContact O-N 2.93Å
36	L	42.1	Very low	42.8	Very low	96 Å²	96	101.6 Å²	101.6	50%	0.503	56%	0.563	S	S	.	*	H	α-helix	trans	-80.5	-20.6	-179.8	-74	167.1	0	0	0	113.7	L32 G33 V267	L32-L36 HydrophobicContact CG-CD1 4.34Å; L32-L36 WeakPolarHBondContact O-CB 3.45Å; L32-L36 WeakPolarHBondContact O-CD1 3.17Å; L32-L36 WeakPolarHBondContact O-CG 3.48Å; L32-L36 PolarHBondContact O-N 3.42Å; G33-L36 PolarHBondContact O-N 3.05Å; L36-V267 HydrophobicContact CD2-CG2 4.43Å
37	D	37	Very low	45	Very low	140 Å²	140	105.5 Å²	105.5	75%	0.749	57%	0.573	S	S	*	*	S	Bend	trans	-108.6	2.4	-178.2	-88.5	-23.6	0	0	0	114.7	G33 P39	G33-D37 PolarHBondContact O-N 2.82Å; D37-P39 WeakPolarHBondContact O-CD 3.08Å
38	Y	33.6	Very low	47.4	Very low	190 Å²	190	102.4 Å²	102.4	75%	0.745	56%	0.556	S	S	*	*			trans	-78.6	110.6	165.5	-100.9	-84.9	0	0	0	108.9	K34	K34-Y38 WeakPolarHBondContact O-CD2 3.41Å; K34-Y38 PolarHBondContact O-N 3.47Å
39	P	36.8	Very low	49.8	Very low	58 Å²	58	104.6 Å²	104.6	38%	0.377	56%	0.558	S	S	.	*			trans	-60.9	145.3	161.8	-1.1	19	0	0	0	106.2	D37	D37-P39 WeakPolarHBondContact O-CD 3.08Å
40	A	39.3	Very low	52.2	Low	83 Å²	83	109 Å²	109	69%	0.686	58%	0.576	S	S	*	*	S	Bend	trans	-42.6	132.2	163.5	0	0	0	0	0	108.4	G42	A40-G42 PolarHBondContact O-N 3.4Å
41	P	34.5	Very low	54.8	Low	141 Å²	141	109.2 Å²	109.2	92%	0.916	57%	0.571	S	S	*	*	T	Hydrogen-bonded Turn	trans	-57.4	105.7	-167.9	21.7	-31.2	0	0	0	109
42	G	45.4	Very low	57.5	Low	75 Å²	75	104.9 Å²	104.9	77%	0.773	55%	0.553	S	S	*	*	T	Hydrogen-bonded Turn	trans	146.3	-16.2	-179.7	0	0	0	0	0	118.7	A40	A40-G42 PolarHBondContact O-N 3.4Å
43	L	51.3	Low	60.4	Low	101 Å²	101	100.1 Å²	100.1	53%	0.529	53%	0.528	S	S	.	.			trans	-104.4	98.9	174.6	-101.5	85.9	0	0	0	112	R45	L43-R45 PolarHBondContact O-N 2.92Å
44	Q	61.6	Low	63.3	Low	186 Å²	186	100.2 Å²	100.2	87%	0.869	52%	0.518	S	S	*	.	P	Polyproline II helix	trans	-58.9	131.6	167.3	-127.4	170.1	-3	0	0	109.4
45	R	75.3	Confident	66.2	Low	97 Å²	97	98.2 Å²	98.2	37%	0.366	51%	0.513	S	S	.	.	P	Polyproline II helix	trans	-61.4	123	177.2	-174.5	-179.6	-175.9	-166.6	-9	108.6	Y10 L43 E47 Y259 Y260	Y10-R45 PolarHBondContact OH-NH2 3.34Å; L43-R45 PolarHBondContact O-N 2.92Å; R45-E47 PolarHBondContact O-N 3.2Å; R45-Y259 HydrophobicContact CG-CE1 4.17Å; R45-Y260 PolarHBondContact NE-OH 3.15Å; R45-Y260 PolarHBondContact NH2-OH 3.35Å
46	P	82.8	Confident	69.2	Low	31 Å²	31	92.3 Å²	92.3	20%	0.201	48%	0.482	C	S	.	.	P	Polyproline II helix	trans	-66	136.5	179.7	24	-30.5	0	0	0	110.2	Y256 Y259	P46-Y256 WeakPolarHBondContact O-CD2 3.26Å; P46-Y256 WeakPolarHBondContact O-CE2 3.33Å; P46-Y259 HydrophobicContact CG-CD1 4.31Å; P46-Y259 HydrophobicContact CG-CD2 4.16Å; P46-Y259 HydrophobicContact CG-CG 3.78Å
47	E	85.3	Confident	71.9	Confident	133 Å²	133	87.8 Å²	87.8	62%	0.621	46%	0.458	S	S	*	.	P	Polyproline II helix	trans	-79.3	149.5	173.2	-66.4	-173	160.3	0	0	111.1	R45 R49	R45-E47 PolarHBondContact O-N 3.2Å; E47-R49 VanDerWaalsContact C-N 3.34Å; E47-R49 PolarHBondContact O-N 3.34Å
48	D	87.7	Confident	74.7	Confident	15 Å²	15	83.1 Å²	83.1	8%	0.08	43%	0.431	C	S	.	.			trans	-75.6	85.1	174.2	-171.2	13	0	0	0	110.2	F50 N51 G52 A53 Y54 Y256	D48-F50 PolarHBondContact O-N 3.01Å; D48-N51 PolarHBondContact O-N 3.05Å; D48-N51 VanDerWaalsContact OD2-C 3.28Å; D48-N51 WeakPolarHBondContact OD2-CA 3.43Å; D48-G52 PolarHBondContact OD1-N 2.92Å; D48-A53 WeakPolarHBondContact OD1-CB 3.21Å; D48-A53 PolarHBondContact OD1-N 3.04Å; D48-A53 PolarHBondContact OD2-N 3.36Å; D48-Y54 PolarHBondContact OD2-N 3.17Å; D48-Y256 HydrophobicContact CB-CD1 4.38Å; D48-Y256 HydrophobicContact CB-CD2 3.83Å; D48-Y256 HydrophobicContact CB-CE1 4.28Å; D48-Y256 HydrophobicContact CB-CE2 3.7Å; D48-Y256 HydrophobicContact CB-CG 4.14Å
49	R	85.1	Confident	77.7	Confident	192 Å²	192	75.5 Å²	75.5	73%	0.725	41%	0.406	S	S	*	.	G	3₁₀ helix	trans	-54.3	125.1	-178.7	-65.5	-168.6	-175.8	-176	4.7	110.7	E47 N51 G52	E47-R49 VanDerWaalsContact C-N 3.34Å; E47-R49 PolarHBondContact O-N 3.34Å; R49-N51 PolarHBondContact O-N 3.26Å; R49-N51 VanDerWaalsContact O-N 3.17Å; R49-G52 PolarHBondContact O-N 3.46Å; R49-G52 VanDerWaalsContact O-N 3.16Å
50	F	87.7	Confident	80.6	Confident	196 Å²	196	72.8 Å²	72.8	86%	0.86	39%	0.388	S	S	*	.	G	3₁₀ helix	trans	58	18.7	-176.8	-53.2	-75.2	0	0	0	115.1	D48 G52	D48-F50 PolarHBondContact O-N 3.01Å; F50-G52 PolarHBondContact O-N 3.35Å
51	N	91.6	Very high	83.3	Confident	50 Å²	50	68.9 Å²	68.9	27%	0.267	36%	0.356	S	S	.	.	G	3₁₀ helix	trans	55.7	32.1	-171.6	-53.9	-70.6	0	0	0	112.8	D48 R49 A53 Y54 I55 R196	D48-N51 PolarHBondContact O-N 3.05Å; D48-N51 VanDerWaalsContact OD2-C 3.28Å; D48-N51 WeakPolarHBondContact OD2-CA 3.43Å; R49-N51 PolarHBondContact O-N 3.26Å; R49-N51 VanDerWaalsContact O-N 3.17Å; N51-A53 PolarHBondContact O-N 2.82Å; N51-Y54 WeakPolarHBondContact O-CB 3.34Å; N51-Y54 PolarHBondContact O-N 3.12Å; N51-I55 WeakPolarHBondContact O-CG1 3.2Å; N51-I55 PolarHBondContact O-N 2.94Å; N51-R196 PolarHBondContact OD1-NH1 2.96Å; N51-R196 PolarHBondContact OD1-NH2 3.45Å
52	G	93.9	Very high	86.2	Confident	20 Å²	20	63 Å²	63	21%	0.206	32%	0.317	C	S	.	.	H	α-helix	trans	-59.4	-45.9	-175.1	0	0	0	0	0	112.5	D48 R49 F50 I55 I56	D48-G52 PolarHBondContact OD1-N 2.92Å; R49-G52 PolarHBondContact O-N 3.46Å; R49-G52 VanDerWaalsContact O-N 3.16Å; F50-G52 PolarHBondContact O-N 3.35Å; G52-I55 PolarHBondContact O-N 2.96Å; G52-I56 VanDerWaalsContact O-CG1 3.26Å; G52-I56 WeakPolarHBondContact O-CG1 3.42Å; G52-I56 PolarHBondContact O-N 3.44Å
53	A	94.7	Very high	88.4	Confident	0 Å²	0	59.5 Å²	59.5	0%	0	28%	0.28	C	S	.	.	H	α-helix	trans	-65.6	-40.3	177.5	0	0	0	0	0	111.5	D48 N51 I56 F57 L251 L254 Y256	D48-A53 WeakPolarHBondContact OD1-CB 3.21Å; D48-A53 PolarHBondContact OD1-N 3.04Å; D48-A53 PolarHBondContact OD2-N 3.36Å; N51-A53 PolarHBondContact O-N 2.82Å; A53-I56 PolarHBondContact O-N 3.48Å; A53-F57 WeakPolarHBondContact O-CD2 3.43Å; A53-F57 PolarHBondContact O-N 3.4Å; A53-L251 HydrophobicContact CB-CD1 4.09Å; A53-L254 HydrophobicContact CB-CD1 4.27Å; A53-Y256 HydrophobicContact CB-CD1 3.63Å; A53-Y256 HydrophobicContact CB-CE1 3.9Å
54	Y	95.4	Very high	90.3	Very high	35 Å²	35	54.7 Å²	54.7	14%	0.137	26%	0.256	C	S	.	.	H	α-helix	trans	-56.7	-49.7	174.5	-179	-85.2	0	0	0	112.3	D48 N51 I56 F57 F58 R196 Q199 A200 Q364	D48-Y54 PolarHBondContact OD2-N 3.17Å; N51-Y54 WeakPolarHBondContact O-CB 3.34Å; N51-Y54 PolarHBondContact O-N 3.12Å; Y54-I56 VanDerWaalsContact C-N 3.32Å; Y54-I56 PolarHBondContact O-N 3.06Å; Y54-F57 PolarHBondContact O-N 3.46Å; Y54-F58 PolarHBondContact O-N 3.32Å; Y54-R196 HydrophobicContact CD2-CG 3.77Å; Y54-R196 HydrophobicContact CE2-CG 3.81Å; Y54-Q199 PolarHBondContact OH-OE1 3.1Å; Y54-A200 HydrophobicContact CD1-CB 4.31Å; Y54-A200 HydrophobicContact CD2-CB 3.53Å; Y54-A200 HydrophobicContact CE1-CB 4.23Å; Y54-A200 HydrophobicContact CE2-CB 3.46Å; Y54-A200 VanDerWaalsContact CE2-CB 3.46Å; Y54-A200 HydrophobicContact CG-CB 3.97Å; Y54-Q364 PolarHBondContact OH-NE2 3.08Å
55	I	96.3	Very high	91.5	Very high	93 Å²	93	49.3 Å²	49.3	48%	0.477	23%	0.232	S	C	.	.	H	α-helix	trans	-62.4	-42.4	179.9	-67.1	167.2	0	0	0	110.3	N51 G52 F58 C59	N51-I55 WeakPolarHBondContact O-CG1 3.2Å; N51-I55 PolarHBondContact O-N 2.94Å; G52-I55 PolarHBondContact O-N 2.96Å; I55-F58 PolarHBondContact O-N 3.2Å; I55-C59 PolarHBondContact O-N 3.14Å; I55-C59 PolarHBondContact O-SG 3.38Å; I55-C59 VanDerWaalsContact O-SG 3.35Å
56	I	97	Very high	92.1	Very high	7 Å²	7	44.7 Å²	44.7	4%	0.036	22%	0.215	C	C	.	.	H	α-helix	trans	-61	-49.3	177.6	-68	168.9	0	0	0	110.8	G52 A53 Y54 F58 C59 L60 L247 L250 L251 L254	G52-I56 VanDerWaalsContact O-CG1 3.26Å; G52-I56 WeakPolarHBondContact O-CG1 3.42Å; G52-I56 PolarHBondContact O-N 3.44Å; A53-I56 PolarHBondContact O-N 3.48Å; Y54-I56 VanDerWaalsContact C-N 3.32Å; Y54-I56 PolarHBondContact O-N 3.06Å; I56-F58 VanDerWaalsContact C-N 3.3Å; I56-F58 PolarHBondContact O-N 2.91Å; I56-C59 PolarHBondContact O-N 2.66Å; I56-L60 HydrophobicContact CG2-CD1 3.87Å; I56-L60 HydrophobicContact CG2-CG 4.14Å; I56-L60 VanDerWaalsContact O-CG 3.29Å; I56-L60 WeakPolarHBondContact O-CG 3.34Å; I56-L60 PolarHBondContact O-N 3.3Å; I56-L247 HydrophobicContact CG1-CB 4.49Å; I56-L247 HydrophobicContact CG1-CD2 4.31Å; I56-L247 HydrophobicContact CG2-CB 4.08Å; I56-L250 HydrophobicContact CD1-CB 4.47Å; I56-L250 HydrophobicContact CD1-CD2 4.25Å; I56-L250 HydrophobicContact CD1-CG 4.25Å; I56-L251 HydrophobicContact CB-CD1 4.37Å; I56-L251 HydrophobicContact CD1-CB 4.22Å; I56-L251 HydrophobicContact CD1-CD1 4.21Å; I56-L251 HydrophobicContact CG2-CB 4.01Å; I56-L251 HydrophobicContact CG2-CD1 4.16Å; I56-L251 HydrophobicContact CG2-CD2 4.36Å; I56-L251 HydrophobicContact CG2-CG 4.4Å; I56-L254 HydrophobicContact CD1-CD1 3.75Å
57	F	96.9	Very high	92.3	Very high	0 Å²	0	43.2 Å²	43.2	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-60.7	-40.1	177.8	-80.9	-65.1	0	0	0	112.2	A53 Y54 L60 G61 V186 L189 T190 F193 N197 A200 L201 L251	A53-F57 WeakPolarHBondContact O-CD2 3.43Å; A53-F57 PolarHBondContact O-N 3.4Å; Y54-F57 PolarHBondContact O-N 3.46Å; F57-L60 HydrophobicContact CD1-CD1 4.43Å; F57-L60 PolarHBondContact O-N 2.86Å; F57-G61 PolarHBondContact O-N 2.95Å; F57-V186 HydrophobicContact CD1-CG1 4.08Å; F57-V186 HydrophobicContact CE1-CG1 4.1Å; F57-L189 HydrophobicContact CE1-CD2 4.31Å; F57-L189 HydrophobicContact CZ-CD2 4.33Å; F57-L189 HydrophobicContact CZ-CG 4.47Å; F57-T190 HydrophobicContact CD1-CG2 3.55Å; F57-T190 HydrophobicContact CE1-CG2 3.39Å; F57-T190 HydrophobicContact CG-CG2 4.27Å; F57-T190 HydrophobicContact CZ-CG2 3.98Å; F57-F193 AromaticContact CE2-CD1 3.78Å; F57-F193 HydrophobicContact CE2-CD1 3.78Å; F57-F193 AromaticContact CE2-CE1 3.81Å; F57-F193 HydrophobicContact CE2-CE1 3.81Å; F57-F193 HydrophobicContact CE2-CG 4.19Å; F57-F193 HydrophobicContact CE2-CZ 4.27Å; F57-F193 HydrophobicContact CZ-CD1 4.17Å; F57-F193 HydrophobicContact CZ-CD2 4.22Å; F57-F193 HydrophobicContact CZ-CE1 4.1Å; F57-F193 HydrophobicContact CZ-CE2 4.16Å; F57-F193 HydrophobicContact CZ-CG 4.22Å; F57-F193 HydrophobicContact CZ-CZ 4.09Å; F57-N197 HydrophobicContact CD2-CB 3.67Å; F57-N197 HydrophobicContact CE2-CB 3.88Å; F57-N197 HydrophobicContact CG-CB 4.37Å; F57-A200 HydrophobicContact CB-CB 4.13Å; F57-L201 HydrophobicContact CB-CB 4.27Å; F57-L201 HydrophobicContact CD1-CB 4.47Å; F57-L201 WeakPolarHBondContact O-CA 3.33Å; F57-L201 WeakPolarHBondContact O-CD1 3.17Å; F57-L251 HydrophobicContact CE1-CD2 4.11Å; F57-L251 HydrophobicContact CE2-CD1 4.19Å; F57-L251 HydrophobicContact CE2-CD2 4.26Å; F57-L251 HydrophobicContact CZ-CD2 3.82Å
58	F	96.8	Very high	92.4	Very high	42 Å²	42	40.8 Å²	40.8	18%	0.184	19%	0.191	C	C	.	.	H	α-helix	trans	-59	-47.7	174.1	-172.7	-94.8	0	0	0	112.1	Y54 I55 I56 L60 G61 I62 A200 G204 M207	Y54-F58 PolarHBondContact O-N 3.32Å; I55-F58 PolarHBondContact O-N 3.2Å; I56-F58 VanDerWaalsContact C-N 3.3Å; I56-F58 PolarHBondContact O-N 2.91Å; F58-L60 PolarHBondContact O-N 3.29Å; F58-G61 PolarHBondContact O-N 2.83Å; F58-G61 VanDerWaalsContact O-N 3.17Å; F58-I62 HydrophobicContact CD1-CD1 3.99Å; F58-I62 HydrophobicContact CE1-CD1 3.73Å; F58-I62 HydrophobicContact CE1-CG1 4.4Å; F58-I62 PolarHBondContact O-N 2.81Å; F58-I62 VanDerWaalsContact O-N 3.16Å; F58-A200 WeakPolarHBondContact CA-O 3.4Å; F58-A200 HydrophobicContact CB-CB 4.33Å; F58-A200 WeakPolarHBondContact CD2-O 3.31Å; F58-G204 VanDerWaalsContact O-CA 3.26Å; F58-G204 WeakPolarHBondContact O-CA 3.46Å; F58-M207 HydrophobicContact CE1-CB 4.32Å; F58-M207 HydrophobicContact CE1-CG 4.2Å; F58-M207 HydrophobicContact CZ-CB 3.79Å; F58-M207 HydrophobicContact CZ-CE 4.03Å; F58-M207 HydrophobicContact CZ-CG 4.04Å
59	C	96.8	Very high	92.4	Very high	31 Å²	31	41.5 Å²	41.5	21%	0.209	19%	0.194	C	C	.	.	H	α-helix	trans	-64.8	-39.3	177.1	-68.9	0	0	0	0	113	I55 I56 G61 I62 G63 L247	I55-C59 PolarHBondContact O-N 3.14Å; I55-C59 PolarHBondContact O-SG 3.38Å; I55-C59 VanDerWaalsContact O-SG 3.35Å; I56-C59 PolarHBondContact O-N 2.66Å; C59-G61 PolarHBondContact O-N 3.5Å; C59-I62 WeakPolarHBondContact O-CB 3.47Å; C59-I62 PolarHBondContact O-N 2.74Å; C59-G63 PolarHBondContact O-N 3.03Å; C59-L247 HydrophobicContact CB-CD1 3.4Å
60	L	97.1	Very high	92.6	Very high	0 Å²	0	32.4 Å²	32.4	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-61.7	-34.5	174.1	-68.6	175.4	0	0	0	111.4	I56 F57 F58 G63 G64 F182 V186 L201 C244 Y248	I56-L60 HydrophobicContact CG2-CD1 3.87Å; I56-L60 HydrophobicContact CG2-CG 4.14Å; I56-L60 VanDerWaalsContact O-CG 3.29Å; I56-L60 WeakPolarHBondContact O-CG 3.34Å; I56-L60 PolarHBondContact O-N 3.3Å; F57-L60 HydrophobicContact CD1-CD1 4.43Å; F57-L60 PolarHBondContact O-N 2.86Å; F58-L60 PolarHBondContact O-N 3.29Å; L60-G63 PolarHBondContact O-N 2.7Å; L60-G64 PolarHBondContact O-N 3.27Å; L60-F182 HydrophobicContact CB-CZ 4.26Å; L60-F182 HydrophobicContact CD2-CE2 4.31Å; L60-F182 HydrophobicContact CD2-CZ 4.02Å; L60-V186 HydrophobicContact CB-CG1 4.32Å; L60-V186 HydrophobicContact CD1-CG1 3.98Å; L60-L201 HydrophobicContact CB-CD1 4.05Å; L60-C244 HydrophobicContact CD2-CB 3.91Å; L60-C244 WeakPolarHBondContact CD2-O 3.2Å; L60-Y248 HydrophobicContact CD1-CD2 4.25Å
61	G	96.4	Very high	92.6	Very high	2 Å²	2	23.1 Å²	23.1	2%	0.021	12%	0.119	C	C	.	.	H	α-helix	trans	-63.2	-44.8	173.9	0	0	0	0	0	112.2	F57 F58 C59 G64 L201 G204 G205	F57-G61 PolarHBondContact O-N 2.95Å; F58-G61 PolarHBondContact O-N 2.83Å; F58-G61 VanDerWaalsContact O-N 3.17Å; C59-G61 PolarHBondContact O-N 3.5Å; G61-G64 PolarHBondContact O-N 3Å; G61-L201 WeakPolarHBondContact CA-O 3.15Å; G61-G204 CarbonylContact C-O 3.55Å; G61-G205 WeakPolarHBondContact O-CA 3.37Å
62	I	95.1	Very high	92.3	Very high	17 Å²	17	23.6 Å²	23.6	9%	0.087	12%	0.124	C	C	.	.	H	α-helix	trans	-58.7	-53.5	175.9	-62.3	169.8	0	0	0	109.8	F58 C59 G64 L65 L66 G204 M207 F240	F58-I62 HydrophobicContact CD1-CD1 3.99Å; F58-I62 HydrophobicContact CE1-CD1 3.73Å; F58-I62 HydrophobicContact CE1-CG1 4.4Å; F58-I62 PolarHBondContact O-N 2.81Å; F58-I62 VanDerWaalsContact O-N 3.16Å; C59-I62 WeakPolarHBondContact O-CB 3.47Å; C59-I62 PolarHBondContact O-N 2.74Å; I62-G64 PolarHBondContact O-N 2.65Å; I62-L65 PolarHBondContact O-N 3.45Å; I62-L66 HydrophobicContact CG2-CB 4.35Å; I62-L66 HydrophobicContact CG2-CD2 4.28Å; I62-L66 WeakPolarHBondContact O-CB 3.23Å; I62-L66 PolarHBondContact O-N 3.01Å; I62-G204 VanDerWaalsContact CA-O 3.28Å; I62-G204 WeakPolarHBondContact CA-O 3.33Å; I62-G204 WeakPolarHBondContact CG1-O 3.46Å; I62-G204 PolarHBondContact N-O 3.5Å; I62-M207 HydrophobicContact CD1-CB 4.27Å; I62-M207 HydrophobicContact CD1-CG 3.75Å; I62-M207 HydrophobicContact CG1-CB 3.94Å; I62-M207 HydrophobicContact CG1-CG 3.92Å; I62-F240 HydrophobicContact CG2-CD1 4.03Å; I62-F240 HydrophobicContact CG2-CE1 3.76Å
63	G	92.5	Very high	91.8	Very high	1 Å²	1	24.1 Å²	24.1	1%	0.01	12%	0.123	C	C	.	.	H	α-helix	trans	-67.2	-16.5	-178	0	0	0	0	0	114.7	C59 L60 P67 C244	C59-G63 PolarHBondContact O-N 3.03Å; L60-G63 PolarHBondContact O-N 2.7Å; G63-P67 WeakPolarHBondContact O-CD 3.35Å; G63-P67 WeakPolarHBondContact O-CG 3.44Å; G63-C244 VanDerWaalsContact CA-SG 3.59Å
64	G	90.5	Very high	91.3	Very high	1 Å²	1	24.3 Å²	24.3	1%	0.01	13%	0.125	C	C	.	.	H	α-helix	trans	-71.3	-30.8	175.3	0	0	0	0	0	114.3	L60 G61 I62 F182 N183	L60-G64 PolarHBondContact O-N 3.27Å; G61-G64 PolarHBondContact O-N 3Å; I62-G64 PolarHBondContact O-N 2.65Å; G64-F182 VanDerWaalsContact CA-CE1 3.47Å; G64-N183 WeakPolarHBondContact CA-OD1 3.41Å; G64-N183 PolarHBondContact O-ND2 3.07Å
65	L	86.7	Confident	90.5	Very high	72 Å²	72	28.3 Å²	28.3	38%	0.377	14%	0.143	S	C	.	.	H	α-helix	trans	-113.8	-30.8	-176.6	-69.5	178	0	0	0	113.4	I62 W68 N69 G205	I62-L65 PolarHBondContact O-N 3.45Å; L65-W68 PolarHBondContact O-N 3.17Å; L65-N69 PolarHBondContact O-N 2.77Å; L65-G205 WeakPolarHBondContact CD1-O 3.27Å
66	L	87.8	Confident	89.8	Confident	0 Å²	0	29 Å²	29	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-56.3	-44.8	-174.1	-165	77.9	0	0	0	113.9	I62 W68 N69 F70 G208 V211 S212 F240	I62-L66 HydrophobicContact CG2-CB 4.35Å; I62-L66 HydrophobicContact CG2-CD2 4.28Å; I62-L66 WeakPolarHBondContact O-CB 3.23Å; I62-L66 PolarHBondContact O-N 3.01Å; L66-W68 PolarHBondContact O-N 3.18Å; L66-N69 PolarHBondContact O-N 3.07Å; L66-F70 HydrophobicContact CD1-CE1 3.98Å; L66-F70 HydrophobicContact CD1-CE2 4.21Å; L66-F70 HydrophobicContact CD1-CZ 3.77Å; L66-F70 HydrophobicContact CD2-CE2 3.8Å; L66-F70 HydrophobicContact CD2-CZ 4.05Å; L66-F70 HydrophobicContact CG-CD2 4.17Å; L66-F70 HydrophobicContact CG-CE1 4.33Å; L66-F70 HydrophobicContact CG-CE2 3.76Å; L66-F70 HydrophobicContact CG-CZ 3.85Å; L66-F70 PolarHBondContact O-N 2.93Å; L66-G208 WeakPolarHBondContact CD1-O 3.5Å; L66-V211 HydrophobicContact CD1-CB 3.89Å; L66-V211 HydrophobicContact CD1-CG1 3.73Å; L66-S212 WeakPolarHBondContact CD1-OG 3.34Å; L66-F240 HydrophobicContact CD2-CB 4.19Å; L66-F240 HydrophobicContact CD2-CD1 3.96Å; L66-F240 HydrophobicContact CD2-CD2 3.75Å; L66-F240 HydrophobicContact CD2-CE1 4.26Å; L66-F240 HydrophobicContact CD2-CE2 4.06Å; L66-F240 HydrophobicContact CD2-CG 3.68Å; L66-F240 HydrophobicContact CD2-CZ 4.3Å
67	P	86.4	Confident	89.4	Confident	0 Å²	0	28.7 Å²	28.7	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-62.7	-44.9	-179.2	-22.2	34.6	0	0	0	112.5	G63 F70 F71 F146 A237 L241	G63-P67 WeakPolarHBondContact O-CD 3.35Å; G63-P67 WeakPolarHBondContact O-CG 3.44Å; P67-F70 PolarHBondContact O-N 2.96Å; P67-F71 PolarHBondContact O-N 3.26Å; P67-F71 VanDerWaalsContact O-N 3.07Å; P67-F146 HydrophobicContact CB-CD2 4.34Å; P67-F146 HydrophobicContact CB-CE2 3.4Å; P67-F146 VanDerWaalsContact CB-CE2 3.4Å; P67-F146 HydrophobicContact CB-CZ 3.54Å; P67-F146 WeakPolarHBondContact O-CZ 3.27Å; P67-A237 HydrophobicContact CB-CB 4.04Å; P67-L241 HydrophobicContact CB-CD1 4.34Å; P67-L241 HydrophobicContact CG-CD1 4.17Å; P67-L241 HydrophobicContact CG-CD2 3.85Å; P67-L241 HydrophobicContact CG-CG 3.83Å
68	W	87.9	Confident	88.9	Confident	83 Å²	83	28.9 Å²	28.9	31%	0.314	14%	0.143	S	C	.	.	H	α-helix	trans	-62.7	-44.3	177.3	-177.2	93.6	0	0	0	111	L65 L66 F70 F71 V72 M172	L65-W68 PolarHBondContact O-N 3.17Å; L66-W68 PolarHBondContact O-N 3.18Å; W68-F70 PolarHBondContact O-N 3.17Å; W68-F71 WeakPolarHBondContact O-CB 3.17Å; W68-F71 PolarHBondContact O-N 3.08Å; W68-V72 HydrophobicContact CD2-CG2 4.16Å; W68-V72 HydrophobicContact CE3-CG2 4.29Å; W68-V72 HydrophobicContact CH2-CG2 4Å; W68-V72 HydrophobicContact CZ2-CG2 3.87Å; W68-V72 HydrophobicContact CZ3-CG2 4.22Å; W68-V72 WeakPolarHBondContact O-CG2 3.49Å; W68-V72 PolarHBondContact O-N 2.93Å; W68-V72 VanDerWaalsContact O-N 3.12Å; W68-M172 HydrophobicContact CG-CE 4.47Å
69	N	88.2	Confident	88.3	Confident	29 Å²	29	29 Å²	29	16%	0.155	15%	0.152	C	C	.	.	H	α-helix	trans	-60.4	-45.1	178	-71.4	-15.2	0	0	0	112.1	L65 L66 F71 V72 T73 S212	L65-N69 PolarHBondContact O-N 2.77Å; L66-N69 PolarHBondContact O-N 3.07Å; N69-F71 VanDerWaalsContact C-N 3.31Å; N69-F71 PolarHBondContact O-N 3.29Å; N69-V72 PolarHBondContact O-N 2.73Å; N69-T73 VanDerWaalsContact O-CB 3.32Å; N69-T73 WeakPolarHBondContact O-CB 3.4Å; N69-T73 PolarHBondContact O-N 2.8Å; N69-T73 PolarHBondContact O-OG1 3.2Å; N69-S212 WeakPolarHBondContact CB-OG 3.37Å; N69-S212 PolarHBondContact ND2-OG 3.42Å
70	F	88.5	Confident	87.8	Confident	2 Å²	2	33.2 Å²	33.2	1%	0.009	16%	0.164	C	C	.	.	H	α-helix	trans	-64	-35.3	177.6	-77.2	-10.7	0	0	0	112.8	L66 P67 W68 T73 A74 V211 A215 F233 M236 A237	L66-F70 HydrophobicContact CD1-CE1 3.98Å; L66-F70 HydrophobicContact CD1-CE2 4.21Å; L66-F70 HydrophobicContact CD1-CZ 3.77Å; L66-F70 HydrophobicContact CD2-CE2 3.8Å; L66-F70 HydrophobicContact CD2-CZ 4.05Å; L66-F70 HydrophobicContact CG-CD2 4.17Å; L66-F70 HydrophobicContact CG-CE1 4.33Å; L66-F70 HydrophobicContact CG-CE2 3.76Å; L66-F70 HydrophobicContact CG-CZ 3.85Å; L66-F70 PolarHBondContact O-N 2.93Å; P67-F70 PolarHBondContact O-N 2.96Å; W68-F70 PolarHBondContact O-N 3.17Å; F70-T73 PolarHBondContact O-N 2.95Å; F70-A74 PolarHBondContact O-N 3.42Å; F70-V211 HydrophobicContact CZ-CG1 4.42Å; F70-A215 HydrophobicContact CE1-CB 3.85Å; F70-A215 HydrophobicContact CZ-CB 4.39Å; F70-F233 HydrophobicContact CB-CB 4.15Å; F70-F233 HydrophobicContact CB-CD1 4.4Å; F70-F233 AromaticContact CD1-CD1 3.73Å; F70-F233 HydrophobicContact CD1-CD1 3.73Å; F70-F233 HydrophobicContact CD1-CE1 4.17Å; F70-F233 HydrophobicContact CD2-CD1 4.38Å; F70-F233 VanDerWaalsContact CD2-O 3.27Å; F70-F233 WeakPolarHBondContact CD2-O 3.08Å; F70-F233 HydrophobicContact CE1-CD1 4.01Å; F70-F233 HydrophobicContact CE1-CE1 4.24Å; F70-F233 HydrophobicContact CG-CB 4.35Å; F70-F233 AromaticContact CG-CD1 3.93Å; F70-F233 HydrophobicContact CG-CD1 3.93Å; F70-F233 HydrophobicContact CZ-CD1 4.47Å; F70-M236 HydrophobicContact CD2-CB 4.3Å; F70-M236 HydrophobicContact CE2-CB 3.64Å; F70-M236 HydrophobicContact CE2-CE 4.38Å; F70-M236 HydrophobicContact CZ-CE 4.38Å; F70-A237 HydrophobicContact CD2-CB 4.16Å
71	F	88.1	Confident	87.3	Confident	0 Å²	0	34 Å²	34	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-62.6	-46.2	175.1	-162.8	-77.6	0	0	0	112.2	P67 W68 N69 W78 L107 M149 T168 M172 I175 F234	P67-F71 PolarHBondContact O-N 3.26Å; P67-F71 VanDerWaalsContact O-N 3.07Å; W68-F71 WeakPolarHBondContact O-CB 3.17Å; W68-F71 PolarHBondContact O-N 3.08Å; N69-F71 VanDerWaalsContact C-N 3.31Å; N69-F71 PolarHBondContact O-N 3.29Å; F71-W78 HydrophobicContact CD1-CH2 4.39Å; F71-W78 AromaticContact CD1-CZ2 3.7Å; F71-W78 HydrophobicContact CD1-CZ2 3.7Å; F71-W78 HydrophobicContact CD2-CZ2 4.3Å; F71-W78 AromaticContact CE1-CH2 3.72Å; F71-W78 HydrophobicContact CE1-CH2 3.72Å; F71-W78 AromaticContact CE1-CZ2 3.39Å; F71-W78 HydrophobicContact CE1-CZ2 3.39Å; F71-W78 AromaticContact CE2-CH2 3.88Å; F71-W78 HydrophobicContact CE2-CH2 3.88Å; F71-W78 HydrophobicContact CE2-CZ2 4.05Å; F71-W78 HydrophobicContact CG-CZ2 4.15Å; F71-W78 AromaticContact CZ-CH2 3.44Å; F71-W78 HydrophobicContact CZ-CH2 3.44Å; F71-W78 VanDerWaalsContact CZ-CH2 3.44Å; F71-W78 AromaticContact CZ-CZ2 3.61Å; F71-W78 HydrophobicContact CZ-CZ2 3.61Å; F71-W78 HydrophobicContact CZ-CZ3 4.42Å; F71-W78 PolarHBondContact O-NE1 3.49Å; F71-W78 VanDerWaalsContact O-NE1 3.07Å; F71-L107 HydrophobicContact CE1-CD1 4.43Å; F71-L107 HydrophobicContact CE1-CD2 3.87Å; F71-M149 HydrophobicContact CE2-CE 3.82Å; F71-M149 HydrophobicContact CE2-CG 4.09Å; F71-M149 HydrophobicContact CE2-SD 4.21Å; F71-M149 HydrophobicContact CZ-CE 4.11Å; F71-T168 HydrophobicContact CE1-CG2 4.32Å; F71-T168 HydrophobicContact CZ-CG2 3.9Å; F71-M172 HydrophobicContact CD1-CE 4.23Å; F71-M172 HydrophobicContact CD1-SD 3.46Å; F71-M172 WeakPolarHBondContact CD1-SD 3.38Å; F71-M172 HydrophobicContact CE1-CB 4.28Å; F71-M172 HydrophobicContact CE1-CG 4.39Å; F71-M172 HydrophobicContact CE1-SD 3.65Å; F71-M172 HydrophobicContact CG-SD 4.02Å; F71-M172 HydrophobicContact CZ-CB 4.45Å; F71-M172 HydrophobicContact CZ-SD 4.32Å; F71-I175 HydrophobicContact CD2-CD1 4.09Å; F71-I175 HydrophobicContact CE2-CD1 4.1Å; F71-F234 HydrophobicContact CD2-CE1 4.09Å; F71-F234 HydrophobicContact CD2-CZ 4.27Å; F71-F234 HydrophobicContact CE2-CZ 4.46Å
72	V	84.5	Confident	86.6	Confident	61 Å²	61	34.4 Å²	34.4	37%	0.37	17%	0.169	S	C	.	.	H	α-helix	trans	-71.4	-32.8	179.4	178.4	0	0	0	0	111.7	W68 N69 A74 M172	W68-V72 HydrophobicContact CD2-CG2 4.16Å; W68-V72 HydrophobicContact CE3-CG2 4.29Å; W68-V72 HydrophobicContact CH2-CG2 4Å; W68-V72 HydrophobicContact CZ2-CG2 3.87Å; W68-V72 HydrophobicContact CZ3-CG2 4.22Å; W68-V72 WeakPolarHBondContact O-CG2 3.49Å; W68-V72 PolarHBondContact O-N 2.93Å; W68-V72 VanDerWaalsContact O-N 3.12Å; N69-V72 PolarHBondContact O-N 2.73Å; V72-A74 VanDerWaalsContact C-N 3.25Å; V72-A74 PolarHBondContact O-N 3.39Å; V72-M172 HydrophobicContact CG2-CE 3.84Å
73	T	83.4	Confident	85.7	Confident	31 Å²	31	42.4 Å²	42.4	19%	0.19	20%	0.198	C	C	.	.	H	α-helix	trans	-65.7	-26.4	-179.1	-59	0	0	0	0	112.8	N69 F70 K75 L216 F233	N69-T73 VanDerWaalsContact O-CB 3.32Å; N69-T73 WeakPolarHBondContact O-CB 3.4Å; N69-T73 PolarHBondContact O-N 2.8Å; N69-T73 PolarHBondContact O-OG1 3.2Å; F70-T73 PolarHBondContact O-N 2.95Å; T73-K75 PolarHBondContact O-N 2.93Å; T73-L216 HydrophobicContact CG2-CB 3.84Å; T73-L216 HydrophobicContact CG2-CD1 3.83Å; T73-L216 HydrophobicContact CG2-CG 4.32Å; T73-F233 HydrophobicContact CG2-CE2 4.35Å; T73-F233 HydrophobicContact CG2-CZ 4.03Å
74	A	84.1	Confident	84.1	Confident	4 Å²	4	45 Å²	45	3%	0.033	21%	0.212	C	C	.	.			trans	-73	38.2	-178.3	0	0	0	0	0	114.4	F70 V72 E76 Y77 W78 T230	F70-A74 PolarHBondContact O-N 3.42Å; V72-A74 VanDerWaalsContact C-N 3.25Å; V72-A74 PolarHBondContact O-N 3.39Å; A74-E76 PolarHBondContact O-N 3.08Å; A74-Y77 WeakPolarHBondContact O-CB 3.5Å; A74-Y77 PolarHBondContact O-N 3.31Å; A74-Y77 VanDerWaalsContact O-N 3.08Å; A74-W78 HydrophobicContact CB-CZ2 4.43Å; A74-W78 PolarHBondContact O-N 3.23Å; A74-W78 PolarHBondContact O-NE1 3.09Å; A74-T230 HydrophobicContact CB-CG2 4.04Å
75	K	80	Confident	82.2	Confident	118 Å²	118	50.3 Å²	50.3	51%	0.513	25%	0.247	S	C	.	.	H	α-helix	trans	-52.4	-49	-176.1	-178.4	178.5	-179.2	142.8	0	113.3	T73 Y77 W78 A79 E104	T73-K75 PolarHBondContact O-N 2.93Å; K75-Y77 PolarHBondContact O-N 3.21Å; K75-W78 PolarHBondContact O-N 3.46Å; K75-A79 PolarHBondContact O-N 3.16Å; K75-A79 VanDerWaalsContact O-N 3.07Å; K75-E104 WeakPolarHBondContact CD-OE1 3.27Å; K75-E104 WeakPolarHBondContact CE-OE1 3.5Å; K75-E104 WeakPolarHBondContact CG-OE1 3.46Å; K75-E104 IonicContact NZ-OE1 2.66Å; K75-E104 PolarHBondContact NZ-OE1 2.92Å; K75-E104 IonicContact NZ-OE2 3.5Å; K75-E104 PolarHBondContact NZ-OE2 3.07Å
76	E	81.3	Confident	80.3	Confident	107 Å²	107	50.2 Å²	50.2	50%	0.5	25%	0.253	S	S	.	.	H	α-helix	trans	-63.6	-30.8	-177.6	-63.8	-165.4	173.3	0	0	111.8	A74 A79 Y80 V226	A74-E76 PolarHBondContact O-N 3.08Å; E76-A79 PolarHBondContact O-N 3.14Å; E76-Y80 WeakPolarHBondContact O-CB 3.22Å; E76-Y80 PolarHBondContact O-N 3.17Å; E76-V226 HydrophobicContact CB-CG1 3.83Å; E76-V226 HydrophobicContact CB-CG2 4.14Å
77	Y	87.8	Confident	78.2	Confident	1 Å²	1	53.9 Å²	53.9	0%	0.004	28%	0.278	C	S	.	.	H	α-helix	trans	-70	-41.9	177.2	167.7	-100.7	0	0	0	112.5	A74 K75 A79 Y80 K81 V153 F164 T230	A74-Y77 WeakPolarHBondContact O-CB 3.5Å; A74-Y77 PolarHBondContact O-N 3.31Å; A74-Y77 VanDerWaalsContact O-N 3.08Å; K75-Y77 PolarHBondContact O-N 3.21Å; Y77-A79 VanDerWaalsContact C-N 3.32Å; Y77-Y80 PolarHBondContact O-N 3.2Å; Y77-K81 HydrophobicContact CD2-CG 4.05Å; Y77-K81 HydrophobicContact CE1-CG 4.14Å; Y77-K81 HydrophobicContact CE2-CD 4.22Å; Y77-K81 HydrophobicContact CE2-CG 3.5Å; Y77-K81 WeakPolarHBondContact O-CB 3.35Å; Y77-K81 PolarHBondContact O-N 3.21Å; Y77-K81 WeakPolarHBondContact OH-CE 3.3Å; Y77-V153 HydrophobicContact CE1-CG2 4.39Å; Y77-V153 HydrophobicContact CE2-CB 4.41Å; Y77-V153 HydrophobicContact CE2-CG1 4.24Å; Y77-V153 HydrophobicContact CE2-CG2 4.03Å; Y77-V153 WeakPolarHBondContact OH-CA 3.15Å; Y77-F164 HydrophobicContact CE1-CZ 4.34Å; Y77-T230 WeakPolarHBondContact CB-OG1 3.42Å; Y77-T230 HydrophobicContact CD1-CG2 3.68Å; Y77-T230 HydrophobicContact CD2-CG2 4.02Å; Y77-T230 HydrophobicContact CE1-CG2 4.04Å; Y77-T230 HydrophobicContact CE2-CG2 4.37Å; Y77-T230 HydrophobicContact CG-CG2 3.67Å
78	W	88.1	Confident	76	Confident	5 Å²	5	59 Å²	59	2%	0.019	31%	0.312	C	S	.	.	H	α-helix	trans	-61.6	-45.2	175	-52.5	129	0	0	0	110.7	F71 A74 K75 Y80 K81 L82 F103 M149 F164 T168 F234	F71-W78 HydrophobicContact CD1-CH2 4.39Å; F71-W78 AromaticContact CD1-CZ2 3.7Å; F71-W78 HydrophobicContact CD1-CZ2 3.7Å; F71-W78 HydrophobicContact CD2-CZ2 4.3Å; F71-W78 AromaticContact CE1-CH2 3.72Å; F71-W78 HydrophobicContact CE1-CH2 3.72Å; F71-W78 AromaticContact CE1-CZ2 3.39Å; F71-W78 HydrophobicContact CE1-CZ2 3.39Å; F71-W78 AromaticContact CE2-CH2 3.88Å; F71-W78 HydrophobicContact CE2-CH2 3.88Å; F71-W78 HydrophobicContact CE2-CZ2 4.05Å; F71-W78 HydrophobicContact CG-CZ2 4.15Å; F71-W78 AromaticContact CZ-CH2 3.44Å; F71-W78 HydrophobicContact CZ-CH2 3.44Å; F71-W78 VanDerWaalsContact CZ-CH2 3.44Å; F71-W78 AromaticContact CZ-CZ2 3.61Å; F71-W78 HydrophobicContact CZ-CZ2 3.61Å; F71-W78 HydrophobicContact CZ-CZ3 4.42Å; F71-W78 PolarHBondContact O-NE1 3.49Å; F71-W78 VanDerWaalsContact O-NE1 3.07Å; A74-W78 HydrophobicContact CB-CZ2 4.43Å; A74-W78 PolarHBondContact O-N 3.23Å; A74-W78 PolarHBondContact O-NE1 3.09Å; K75-W78 PolarHBondContact O-N 3.46Å; W78-Y80 PolarHBondContact O-N 3.38Å; W78-K81 PolarHBondContact O-N 2.89Å; W78-L82 VanDerWaalsContact O-CB 3.26Å; W78-L82 WeakPolarHBondContact O-CB 3.23Å; W78-L82 VanDerWaalsContact O-CG 3.23Å; W78-L82 WeakPolarHBondContact O-CG 3.49Å; W78-L82 PolarHBondContact O-N 3.1Å; W78-F103 HydrophobicContact CB-CD1 3.69Å; W78-F103 HydrophobicContact CB-CE1 3.3Å; W78-F103 HydrophobicContact CB-CZ 4.02Å; W78-F103 AromaticContact CD1-CE1 3.6Å; W78-F103 AromaticContact CD2-CE1 3.76Å; W78-F103 HydrophobicContact CD2-CE1 3.76Å; W78-F103 AromaticContact CD2-CZ 3.98Å; W78-F103 HydrophobicContact CD2-CZ 3.98Å; W78-F103 HydrophobicContact CE3-CE1 4.32Å; W78-F103 HydrophobicContact CE3-CZ 4.08Å; W78-F103 HydrophobicContact CG-CD1 4.06Å; W78-F103 AromaticContact CG-CE1 3.25Å; W78-F103 HydrophobicContact CG-CE1 3.25Å; W78-F103 AromaticContact CG-CZ 3.93Å; W78-F103 HydrophobicContact CG-CZ 3.93Å; W78-M149 HydrophobicContact CH2-CE 3.58Å; W78-M149 HydrophobicContact CZ3-CE 3.97Å; W78-F164 HydrophobicContact CZ3-CZ 4.13Å; W78-T168 HydrophobicContact CE3-CG2 4.03Å; W78-T168 HydrophobicContact CH2-CG2 3.88Å; W78-T168 HydrophobicContact CZ3-CG2 3.45Å; W78-T168 VanDerWaalsContact CZ3-CG2 3.45Å; W78-F234 HydrophobicContact CH2-CE2 4.42Å; W78-F234 AromaticContact CH2-CZ 3.77Å; W78-F234 HydrophobicContact CH2-CZ 3.77Å; W78-F234 AromaticContact CZ2-CZ 3.83Å; W78-F234 HydrophobicContact CZ2-CZ 3.83Å
79	A	83.9	Confident	73.8	Confident	44 Å²	44	60.3 Å²	60.3	36%	0.364	34%	0.34	S	S	.	.	H	α-helix	trans	-59.6	-45	174.3	0	0	0	0	0	111.7	K75 E76 Y77 K81 R83	K75-A79 PolarHBondContact O-N 3.16Å; K75-A79 VanDerWaalsContact O-N 3.07Å; E76-A79 PolarHBondContact O-N 3.14Å; Y77-A79 VanDerWaalsContact C-N 3.32Å; A79-K81 PolarHBondContact O-N 2.81Å; A79-R83 VanDerWaalsContact O-CB 3.23Å; A79-R83 WeakPolarHBondContact O-CB 3.38Å; A79-R83 PolarHBondContact O-N 2.99Å
80	Y	85.4	Confident	71.4	Confident	119 Å²	119	64 Å²	64	47%	0.467	37%	0.368	S	S	.	.	H	α-helix	trans	-60.5	-45.5	177.6	169.1	-98.4	0	0	0	112.7	E76 Y77 W78 R227	E76-Y80 WeakPolarHBondContact O-CB 3.22Å; E76-Y80 PolarHBondContact O-N 3.17Å; Y77-Y80 PolarHBondContact O-N 3.2Å; W78-Y80 PolarHBondContact O-N 3.38Å; Y80-R227 HydrophobicContact CD1-CG 4.26Å; Y80-R227 HydrophobicContact CE1-CG 3.86Å
81	K	86.3	Confident	69.5	Low	16 Å²	16	66.9 Å²	66.9	7%	0.07	40%	0.399	C	S	.	.	H	α-helix	trans	-74.8	-31	-176.4	-82.3	-68.3	-162.5	162.5	0	114.2	Y77 W78 A79 L152 V155 T157 F164	Y77-K81 HydrophobicContact CD2-CG 4.05Å; Y77-K81 HydrophobicContact CE1-CG 4.14Å; Y77-K81 HydrophobicContact CE2-CD 4.22Å; Y77-K81 HydrophobicContact CE2-CG 3.5Å; Y77-K81 WeakPolarHBondContact O-CB 3.35Å; Y77-K81 PolarHBondContact O-N 3.21Å; Y77-K81 WeakPolarHBondContact OH-CE 3.3Å; W78-K81 PolarHBondContact O-N 2.89Å; A79-K81 PolarHBondContact O-N 2.81Å; K81-L152 PolarHBondContact NZ-O 3.2Å; K81-V155 PolarHBondContact NZ-O 3.47Å; K81-T157 WeakPolarHBondContact CD-OG1 3.49Å; K81-T157 PolarHBondContact NZ-OG1 2.9Å; K81-T157 VanDerWaalsContact NZ-OG1 3.1Å; K81-F164 HydrophobicContact CB-CD1 4.3Å; K81-F164 HydrophobicContact CB-CE1 3.6Å; K81-F164 HydrophobicContact CB-CZ 4.16Å; K81-F164 HydrophobicContact CD-CZ 4.48Å; K81-F164 HydrophobicContact CG-CE1 4.07Å; K81-F164 HydrophobicContact CG-CZ 4.12Å
82	L	82.8	Confident	67.8	Low	12 Å²	12	74.8 Å²	74.8	6%	0.063	44%	0.436	C	S	.	.	H	α-helix	trans	-91.6	-17.2	-176.9	-64.8	171.1	0	0	0	112.5	W78 N84 I99 L100 F103 T161 F164 F165	W78-L82 VanDerWaalsContact O-CB 3.26Å; W78-L82 WeakPolarHBondContact O-CB 3.23Å; W78-L82 VanDerWaalsContact O-CG 3.23Å; W78-L82 WeakPolarHBondContact O-CG 3.49Å; W78-L82 PolarHBondContact O-N 3.1Å; L82-N84 PolarHBondContact O-N 2.77Å; L82-I99 HydrophobicContact CD1-CG2 4.29Å; L82-I99 HydrophobicContact CD2-CG2 4.29Å; L82-L100 HydrophobicContact CB-CD1 3.68Å; L82-F103 HydrophobicContact CD1-CB 4.36Å; L82-F103 HydrophobicContact CD1-CD1 4.25Å; L82-F103 HydrophobicContact CD1-CD2 3.28Å; L82-F103 HydrophobicContact CD1-CE1 4.43Å; L82-F103 HydrophobicContact CD1-CE2 3.54Å; L82-F103 HydrophobicContact CD1-CG 3.69Å; L82-F103 HydrophobicContact CD1-CZ 4.11Å; L82-T161 HydrophobicContact CD2-CG2 4.12Å; L82-F164 HydrophobicContact CD2-CD1 4.17Å; L82-F164 HydrophobicContact CD2-CE1 4.5Å; L82-F165 HydrophobicContact CD2-CB 3.87Å; L82-F165 HydrophobicContact CD2-CD2 4.28Å
83	R	76	Confident	66.5	Low	185 Å²	185	77 Å²	77	70%	0.698	45%	0.446	S	S	*	.	S	Bend	trans	-69.4	115.8	173.9	-161.1	171.9	-171.4	178.4	1.7	109.4	A79 C85	A79-R83 VanDerWaalsContact O-CB 3.23Å; A79-R83 WeakPolarHBondContact O-CB 3.38Å; A79-R83 PolarHBondContact O-N 2.99Å; R83-C85 PolarHBondContact O-N 3.37Å
84	N	58.7	Low	65.5	Low	54 Å²	54	79.9 Å²	79.9	29%	0.289	47%	0.465	S	S	.	.			trans	-72.8	90.5	-178.4	-164.9	-5.7	0	0	0	110.3	L82 S86 D96	L82-N84 PolarHBondContact O-N 2.77Å; N84-S86 PolarHBondContact O-N 2.9Å; N84-S86 WeakPolarHBondContact OD1-CB 3.11Å; N84-S86 PolarHBondContact OD1-N 3.07Å; N84-D96 PolarHBondContact ND2-OD2 3Å
85	C	50.3	Low	64.4	Low	113 Å²	113	86 Å²	86	76%	0.764	49%	0.493	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70	-5.2	175.4	-66	0	0	0	0	113.2	R83	R83-C85 PolarHBondContact O-N 3.37Å
86	S	45.9	Very low	63.7	Low	71 Å²	71	82.7 Å²	82.7	50%	0.497	48%	0.481	S	S	.	.	T	Hydrogen-bonded Turn	trans	-95.6	-7.9	-173	-48	0	0	0	0	114	N84 P88	N84-S86 PolarHBondContact O-N 2.9Å; N84-S86 WeakPolarHBondContact OD1-CB 3.11Å; N84-S86 PolarHBondContact OD1-N 3.07Å; S86-P88 VanDerWaalsContact O-CD 3.27Å; S86-P88 WeakPolarHBondContact O-CD 3.3Å
87	S	43.9	Very low	63	Low	76 Å²	76	81.7 Å²	81.7	53%	0.531	48%	0.477	S	S	.	.			trans	-109.5	96.9	179	-108.2	0	0	0	0	111.6	A89	S87-A89 PolarHBondContact O-N 2.88Å
88	P	41.6	Very low	62.4	Low	107 Å²	107	85.2 Å²	85.2	70%	0.695	50%	0.496	S	S	*	.			trans	-77.3	111	167.9	30.4	-28.6	0	0	0	109.3	S86 S90	S86-P88 VanDerWaalsContact O-CD 3.27Å; S86-P88 WeakPolarHBondContact O-CD 3.3Å; P88-S90 VanDerWaalsContact C-N 3.32Å; P88-S90 PolarHBondContact O-N 2.66Å
89	A	42.1	Very low	61.8	Low	111 Å²	111	86.2 Å²	86.2	92%	0.917	50%	0.502	S	S	*	.	S	Bend	trans	58.4	12.7	146.1	0	0	0	0	0	120.4	S87	S87-A89 PolarHBondContact O-N 2.88Å
90	S	37.6	Very low	61.4	Low	106 Å²	106	86.9 Å²	86.9	74%	0.741	50%	0.499	S	S	*	.	S	Bend	trans	-128.3	90.6	172.6	64.9	0	0	0	0	112	P88	P88-S90 VanDerWaalsContact C-N 3.32Å; P88-S90 PolarHBondContact O-N 2.66Å
91	G	47.2	Very low	61	Low	64 Å²	64	86 Å²	86	66%	0.66	50%	0.502	S	S	*	.			trans	82.6	85.9	175.4	0	0	0	0	0	112.5	D93	G91-D93 PolarHBondContact O-N 3.37Å
92	E	52.2	Low	60.8	Low	166 Å²	166	91 Å²	91	78%	0.776	52%	0.522	S	S	*	.			trans	-61.8	108.1	162.5	-73.6	178	149	0	0	107.4	P94	E92-P94 WeakPolarHBondContact O-CD 2.99Å
93	D	58.2	Low	60.9	Low	106 Å²	106	91 Å²	91	57%	0.567	52%	0.521	S	S	*	.			trans	-60.4	118.9	169.8	-100.5	-30.7	0	0	0	106.9	G91 E95 D96	G91-D93 PolarHBondContact O-N 3.37Å; D93-E95 PolarHBondContact O-N 3.33Å; D93-D96 PolarHBondContact O-N 2.9Å
94	P	61.8	Low	61.3	Low	92 Å²	92	87.2 Å²	87.2	60%	0.597	51%	0.511	S	S	*	.	H	α-helix	trans	-56.7	-27.7	-174.9	18.5	-29.6	0	0	0	112.4	E92 M97 D98	E92-P94 WeakPolarHBondContact O-CD 2.99Å; P94-M97 PolarHBondContact O-N 3.44Å; P94-D98 PolarHBondContact O-N 2.85Å; P94-D98 VanDerWaalsContact O-N 3.08Å
95	E	61	Low	62.6	Low	132 Å²	132	87.9 Å²	87.9	62%	0.617	52%	0.52	S	S	*	.	H	α-helix	trans	-64.9	-37.2	177.1	-62.6	-171.2	168.8	0	0	113.8	D93 M97 D98 I99	D93-E95 PolarHBondContact O-N 3.33Å; E95-M97 VanDerWaalsContact C-N 3.31Å; E95-M97 PolarHBondContact O-N 2.89Å; E95-D98 PolarHBondContact O-N 3.07Å; E95-I99 WeakPolarHBondContact O-CG1 3.5Å; E95-I99 PolarHBondContact O-N 2.91Å
96	D	65.1	Low	64.5	Low	50 Å²	50	87.5 Å²	87.5	27%	0.267	50%	0.504	S	S	.	.	H	α-helix	trans	-69.5	-33.2	179.8	-86.1	-6	0	0	0	110.8	N84 D93 L100	N84-D96 PolarHBondContact ND2-OD2 3Å; D93-D96 PolarHBondContact O-N 2.9Å; D96-L100 PolarHBondContact O-N 2.82Å
97	M	68	Low	66.6	Low	85 Å²	85	84.6 Å²	84.6	42%	0.419	48%	0.482	S	S	.	.	H	α-helix	trans	-69.9	-38.4	171.7	-88.9	-66.4	-98.4	0	0	112.2	P94 E95 I99 L100 N101	P94-M97 PolarHBondContact O-N 3.44Å; E95-M97 VanDerWaalsContact C-N 3.31Å; E95-M97 PolarHBondContact O-N 2.89Å; M97-I99 VanDerWaalsContact C-N 3.34Å; M97-I99 PolarHBondContact O-N 3.2Å; M97-L100 PolarHBondContact O-N 3.41Å; M97-N101 WeakPolarHBondContact O-CB 3.41Å; M97-N101 PolarHBondContact O-N 3.47Å; M97-N101 PolarHBondContact O-ND2 2.98Å; M97-N101 VanDerWaalsContact O-ND2 3.12Å
98	D	73.7	Confident	68.7	Low	75 Å²	75	83.2 Å²	83.2	40%	0.401	48%	0.476	S	S	.	.	H	α-helix	trans	-62.1	-41.2	175.2	-79.8	-17.2	0	0	0	112	P94 E95 L100 N101 Y102	P94-D98 PolarHBondContact O-N 2.85Å; P94-D98 VanDerWaalsContact O-N 3.08Å; E95-D98 PolarHBondContact O-N 3.07Å; D98-L100 VanDerWaalsContact C-N 3.31Å; D98-L100 PolarHBondContact O-N 2.71Å; D98-N101 PolarHBondContact O-N 3.17Å; D98-Y102 HydrophobicContact CB-CD2 4.21Å; D98-Y102 HydrophobicContact CB-CE2 4.5Å; D98-Y102 WeakPolarHBondContact O-CB 3.48Å; D98-Y102 VanDerWaalsContact O-CD2 3.27Å; D98-Y102 WeakPolarHBondContact O-CD2 3.34Å; D98-Y102 PolarHBondContact O-N 2.96Å
99	I	76.9	Confident	71	Confident	27 Å²	27	82.4 Å²	82.4	14%	0.138	47%	0.469	C	S	.	.	H	α-helix	trans	-57.3	-46.9	176.1	-69.8	169.9	0	0	0	110.5	L82 E95 M97 F103 R162 F165	L82-I99 HydrophobicContact CD1-CG2 4.29Å; L82-I99 HydrophobicContact CD2-CG2 4.29Å; E95-I99 WeakPolarHBondContact O-CG1 3.5Å; E95-I99 PolarHBondContact O-N 2.91Å; M97-I99 VanDerWaalsContact C-N 3.34Å; M97-I99 PolarHBondContact O-N 3.2Å; I99-F103 WeakPolarHBondContact O-CA 3.39Å; I99-F103 VanDerWaalsContact O-CB 3.25Å; I99-F103 WeakPolarHBondContact O-CB 3.41Å; I99-F103 PolarHBondContact O-N 3.46Å; I99-R162 HydrophobicContact CD1-CG 4.37Å; I99-F165 HydrophobicContact CG2-CD2 3.6Å; I99-F165 HydrophobicContact CG2-CE2 3.87Å; I99-F165 HydrophobicContact CG2-CG 4.02Å; I99-F165 HydrophobicContact CG2-CZ 4.48Å
100	L	75.3	Confident	73.4	Confident	58 Å²	58	77.7 Å²	77.7	30%	0.304	43%	0.43	S	S	.	.	H	α-helix	trans	-68.2	-43.3	-178.2	-153.6	88.4	0	0	0	111.9	L82 D96 M97 D98	L82-L100 HydrophobicContact CB-CD1 3.68Å; D96-L100 PolarHBondContact O-N 2.82Å; M97-L100 PolarHBondContact O-N 3.41Å; D98-L100 VanDerWaalsContact C-N 3.31Å; D98-L100 PolarHBondContact O-N 2.71Å
101	N	76.3	Confident	76.1	Confident	100 Å²	100	72.9 Å²	72.9	54%	0.535	40%	0.396	S	S	.	.	H	α-helix	trans	-69.6	-37.9	-175.9	-71.5	-28.5	0	0	0	112.5	M97 D98	M97-N101 WeakPolarHBondContact O-CB 3.41Å; M97-N101 PolarHBondContact O-N 3.47Å; M97-N101 PolarHBondContact O-ND2 2.98Å; M97-N101 VanDerWaalsContact O-ND2 3.12Å; D98-N101 PolarHBondContact O-N 3.17Å
102	Y	82.4	Confident	78.2	Confident	122 Å²	122	72.7 Å²	72.7	48%	0.478	38%	0.382	S	S	.	.	H	α-helix	trans	-104	7.1	-176.5	-60	-71.4	0	0	0	113.7	D98 E104 S105 Y106	D98-Y102 HydrophobicContact CB-CD2 4.21Å; D98-Y102 HydrophobicContact CB-CE2 4.5Å; D98-Y102 WeakPolarHBondContact O-CB 3.48Å; D98-Y102 VanDerWaalsContact O-CD2 3.27Å; D98-Y102 WeakPolarHBondContact O-CD2 3.34Å; D98-Y102 PolarHBondContact O-N 2.96Å; Y102-E104 VanDerWaalsContact C-N 3.29Å; Y102-E104 PolarHBondContact O-N 3.16Å; Y102-S105 WeakPolarHBondContact O-CA 3.47Å; Y102-S105 WeakPolarHBondContact O-CB 3.37Å; Y102-S105 PolarHBondContact O-N 3.36Å; Y102-Y106 WeakPolarHBondContact O-CD2 3.34Å; Y102-Y106 PolarHBondContact O-N 3.37Å
103	F	85.4	Confident	80.1	Confident	11 Å²	11	68.5 Å²	68.5	5%	0.048	37%	0.367	C	S	.	.	H	α-helix	trans	-51.3	-45.3	-176.8	-173.6	-107.5	0	0	0	113.5	W78 L82 I99 S105 Y106 L107 F165 T168 I169	W78-F103 HydrophobicContact CB-CD1 3.69Å; W78-F103 HydrophobicContact CB-CE1 3.3Å; W78-F103 HydrophobicContact CB-CZ 4.02Å; W78-F103 AromaticContact CD1-CE1 3.6Å; W78-F103 AromaticContact CD2-CE1 3.76Å; W78-F103 HydrophobicContact CD2-CE1 3.76Å; W78-F103 AromaticContact CD2-CZ 3.98Å; W78-F103 HydrophobicContact CD2-CZ 3.98Å; W78-F103 HydrophobicContact CE3-CE1 4.32Å; W78-F103 HydrophobicContact CE3-CZ 4.08Å; W78-F103 HydrophobicContact CG-CD1 4.06Å; W78-F103 AromaticContact CG-CE1 3.25Å; W78-F103 HydrophobicContact CG-CE1 3.25Å; W78-F103 AromaticContact CG-CZ 3.93Å; W78-F103 HydrophobicContact CG-CZ 3.93Å; L82-F103 HydrophobicContact CD1-CB 4.36Å; L82-F103 HydrophobicContact CD1-CD1 4.25Å; L82-F103 HydrophobicContact CD1-CD2 3.28Å; L82-F103 HydrophobicContact CD1-CE1 4.43Å; L82-F103 HydrophobicContact CD1-CE2 3.54Å; L82-F103 HydrophobicContact CD1-CG 3.69Å; L82-F103 HydrophobicContact CD1-CZ 4.11Å; I99-F103 WeakPolarHBondContact O-CA 3.39Å; I99-F103 VanDerWaalsContact O-CB 3.25Å; I99-F103 WeakPolarHBondContact O-CB 3.41Å; I99-F103 PolarHBondContact O-N 3.46Å; F103-S105 VanDerWaalsContact C-N 3.3Å; F103-S105 PolarHBondContact O-N 3.36Å; F103-Y106 PolarHBondContact O-N 3.39Å; F103-L107 HydrophobicContact CD1-CD1 3.9Å; F103-L107 HydrophobicContact CD1-CG 4.24Å; F103-L107 HydrophobicContact CE1-CD1 3.22Å; F103-L107 HydrophobicContact CE1-CD2 4.33Å; F103-L107 HydrophobicContact CE1-CG 3.69Å; F103-L107 HydrophobicContact CE2-CG 4.39Å; F103-L107 HydrophobicContact CZ-CD1 3.73Å; F103-L107 HydrophobicContact CZ-CD2 3.98Å; F103-L107 HydrophobicContact CZ-CG 3.77Å; F103-L107 PolarHBondContact O-N 2.66Å; F103-F165 AromaticContact CD2-CD2 3.79Å; F103-F165 HydrophobicContact CD2-CD2 3.79Å; F103-F165 AromaticContact CD2-CE2 3.63Å; F103-F165 HydrophobicContact CD2-CE2 3.63Å; F103-F165 AromaticContact CE2-CD2 3.74Å; F103-F165 HydrophobicContact CE2-CD2 3.74Å; F103-F165 AromaticContact CE2-CE2 3.84Å; F103-F165 HydrophobicContact CE2-CE2 3.84Å; F103-T168 HydrophobicContact CZ-CG2 4.1Å; F103-I169 HydrophobicContact CE2-CD1 4.25Å
104	E	83.5	Confident	81.8	Confident	105 Å²	105	64.6 Å²	64.6	49%	0.491	35%	0.348	S	S	.	.	H	α-helix	trans	-64.2	-37.4	178.8	-66	-175.4	165.1	0	0	112	K75 Y102 L107 A108	K75-E104 WeakPolarHBondContact CD-OE1 3.27Å; K75-E104 WeakPolarHBondContact CE-OE1 3.5Å; K75-E104 WeakPolarHBondContact CG-OE1 3.46Å; K75-E104 IonicContact NZ-OE1 2.66Å; K75-E104 PolarHBondContact NZ-OE1 2.92Å; K75-E104 IonicContact NZ-OE2 3.5Å; K75-E104 PolarHBondContact NZ-OE2 3.07Å; Y102-E104 VanDerWaalsContact C-N 3.29Å; Y102-E104 PolarHBondContact O-N 3.16Å; E104-L107 PolarHBondContact O-N 3.01Å; E104-A108 WeakPolarHBondContact O-CB 3.28Å; E104-A108 PolarHBondContact O-N 3.13Å
105	S	86.3	Confident	83.4	Confident	69 Å²	69	61.4 Å²	61.4	48%	0.483	33%	0.328	S	S	.	.	H	α-helix	trans	-66.2	-42.5	175.4	-63.3	0	0	0	0	110.7	Y102 F103 L107 A108 V109	Y102-S105 WeakPolarHBondContact O-CA 3.47Å; Y102-S105 WeakPolarHBondContact O-CB 3.37Å; Y102-S105 PolarHBondContact O-N 3.36Å; F103-S105 VanDerWaalsContact C-N 3.3Å; F103-S105 PolarHBondContact O-N 3.36Å; S105-L107 PolarHBondContact O-N 3.27Å; S105-A108 PolarHBondContact O-N 3.48Å; S105-V109 WeakPolarHBondContact O-CG2 3.44Å; S105-V109 PolarHBondContact O-N 3.07Å
106	Y	89.4	Confident	84.9	Confident	105 Å²	105	56.8 Å²	56.8	41%	0.412	31%	0.307	S	S	.	.	H	α-helix	trans	-61.1	-44.2	174.1	-68.7	-59.6	0	0	0	111.9	Y102 F103 V109 A110 F165	Y102-Y106 WeakPolarHBondContact O-CD2 3.34Å; Y102-Y106 PolarHBondContact O-N 3.37Å; F103-Y106 PolarHBondContact O-N 3.39Å; Y106-V109 PolarHBondContact O-N 3.42Å; Y106-A110 WeakPolarHBondContact O-CB 3.35Å; Y106-A110 PolarHBondContact O-N 3.13Å; Y106-F165 HydrophobicContact CD2-CE2 4.19Å; Y106-F165 AromaticContact CD2-CZ 3.89Å; Y106-F165 HydrophobicContact CD2-CZ 3.89Å; Y106-F165 HydrophobicContact CE2-CZ 4.37Å; Y106-F165 HydrophobicContact CG-CZ 4.07Å
107	L	90.1	Very high	86.4	Confident	9 Å²	9	59.9 Å²	59.9	5%	0.047	32%	0.323	C	S	.	.	H	α-helix	trans	-63	-40.7	174.8	-76.3	-176.7	0	0	0	112.7	F71 F103 E104 S105 A110 S111 I169 M172	F71-L107 HydrophobicContact CE1-CD1 4.43Å; F71-L107 HydrophobicContact CE1-CD2 3.87Å; F103-L107 HydrophobicContact CD1-CD1 3.9Å; F103-L107 HydrophobicContact CD1-CG 4.24Å; F103-L107 HydrophobicContact CE1-CD1 3.22Å; F103-L107 HydrophobicContact CE1-CD2 4.33Å; F103-L107 HydrophobicContact CE1-CG 3.69Å; F103-L107 HydrophobicContact CE2-CG 4.39Å; F103-L107 HydrophobicContact CZ-CD1 3.73Å; F103-L107 HydrophobicContact CZ-CD2 3.98Å; F103-L107 HydrophobicContact CZ-CG 3.77Å; F103-L107 PolarHBondContact O-N 2.66Å; E104-L107 PolarHBondContact O-N 3.01Å; S105-L107 PolarHBondContact O-N 3.27Å; L107-A110 PolarHBondContact O-N 3.42Å; L107-S111 WeakPolarHBondContact O-CB 3.27Å; L107-S111 PolarHBondContact O-N 3.27Å; L107-S111 PolarHBondContact O-OG 2.9Å; L107-I169 HydrophobicContact CD2-CD1 3.93Å; L107-I169 HydrophobicContact CG-CD1 4.41Å; L107-M172 HydrophobicContact CD2-CB 3.86Å; L107-M172 HydrophobicContact CD2-CG 3.73Å; L107-M172 HydrophobicContact CD2-SD 4.43Å
108	A	88.4	Confident	87.7	Confident	48 Å²	48	60 Å²	60	40%	0.397	32%	0.322	S	S	.	.	H	α-helix	trans	-63.7	-43	178.2	0	0	0	0	0	111.6	E104 S105 S111 T112	E104-A108 WeakPolarHBondContact O-CB 3.28Å; E104-A108 PolarHBondContact O-N 3.13Å; S105-A108 PolarHBondContact O-N 3.48Å; A108-S111 PolarHBondContact O-OG 2.91Å; A108-T112 VanDerWaalsContact O-CB 3.26Å; A108-T112 WeakPolarHBondContact O-CB 3.33Å; A108-T112 PolarHBondContact O-N 3.4Å; A108-T112 PolarHBondContact O-OG1 3.3Å
109	V	90.4	Very high	88.8	Confident	90 Å²	90	56.6 Å²	56.6	55%	0.545	30%	0.303	S	S	.	.	H	α-helix	trans	-68.2	-46.8	176	173.8	0	0	0	0	111	S105 Y106 S111 T112 V113	S105-V109 WeakPolarHBondContact O-CG2 3.44Å; S105-V109 PolarHBondContact O-N 3.07Å; Y106-V109 PolarHBondContact O-N 3.42Å; V109-S111 PolarHBondContact O-N 3.02Å; V109-T112 PolarHBondContact O-N 2.9Å; V109-V113 HydrophobicContact CG1-CG2 4.05Å; V109-V113 PolarHBondContact O-N 3.42Å
110	A	93.4	Very high	89.7	Confident	12 Å²	12	58.6 Å²	58.6	10%	0.099	32%	0.316	C	S	.	.	H	α-helix	trans	-63.8	-23.4	-180	0	0	0	0	0	113	Y106 L107 P114 I169 A173	Y106-A110 WeakPolarHBondContact O-CB 3.35Å; Y106-A110 PolarHBondContact O-N 3.13Å; L107-A110 PolarHBondContact O-N 3.42Å; A110-P114 WeakPolarHBondContact O-CD 3.41Å; A110-P114 WeakPolarHBondContact O-CG 3.48Å; A110-I169 HydrophobicContact CB-CG2 3.79Å; A110-A173 WeakPolarHBondContact O-CA 3.49Å; A110-A173 WeakPolarHBondContact O-CB 3.46Å
111	S	92.9	Very high	90.6	Very high	4 Å²	4	57.4 Å²	57.4	3%	0.028	32%	0.315	C	S	.	.	H	α-helix	trans	-87	-51.8	172.2	54.8	0	0	0	0	112.5	L107 A108 V109 S115 S176	L107-S111 WeakPolarHBondContact O-CB 3.27Å; L107-S111 PolarHBondContact O-N 3.27Å; L107-S111 PolarHBondContact O-OG 2.9Å; A108-S111 PolarHBondContact O-OG 2.91Å; V109-S111 PolarHBondContact O-N 3.02Å; S111-S115 WeakPolarHBondContact O-CB 3.18Å; S111-S115 PolarHBondContact O-N 3.41Å; S111-S115 VanDerWaalsContact O-N 3.1Å; S111-S115 PolarHBondContact O-OG 3.37Å; S111-S176 WeakPolarHBondContact CA-OG 3.38Å; S111-S176 WeakPolarHBondContact CB-OG 3.32Å
112	T	91.3	Very high	91.5	Very high	60 Å²	60	52.7 Å²	52.7	37%	0.368	29%	0.29	S	S	.	.	H	α-helix	trans	-68.6	-45.5	-169.8	-55	0	0	0	0	112.8	A108 V109 S115 L116	A108-T112 VanDerWaalsContact O-CB 3.26Å; A108-T112 WeakPolarHBondContact O-CB 3.33Å; A108-T112 PolarHBondContact O-N 3.4Å; A108-T112 PolarHBondContact O-OG1 3.3Å; V109-T112 PolarHBondContact O-N 2.9Å; T112-S115 PolarHBondContact O-N 3.14Å; T112-L116 HydrophobicContact CG2-CD1 4.2Å; T112-L116 WeakPolarHBondContact O-CG 3.23Å; T112-L116 PolarHBondContact O-N 3.16Å
113	V	92.3	Very high	92.1	Very high	78 Å²	78	47.8 Å²	47.8	47%	0.473	27%	0.271	S	S	.	.	H	α-helix	trans	-65.5	-50.9	-175.2	174.6	0	0	0	0	111.2	V109 S115 L116 L117	V109-V113 HydrophobicContact CG1-CG2 4.05Å; V109-V113 PolarHBondContact O-N 3.42Å; V113-S115 PolarHBondContact O-N 3.27Å; V113-L116 PolarHBondContact O-N 3.12Å; V113-L117 HydrophobicContact CG1-CD1 4.42Å; V113-L117 WeakPolarHBondContact O-CG 3.46Å; V113-L117 PolarHBondContact O-N 2.66Å
114	P	94.6	Very high	92.5	Very high	25 Å²	25	51.3 Å²	51.3	16%	0.162	29%	0.29	C	S	.	.	H	α-helix	trans	-63.2	-40.6	175.6	-25.2	38.9	0	0	0	112.4	A110 L116 L117 F118 A173 S177	A110-P114 WeakPolarHBondContact O-CD 3.41Å; A110-P114 WeakPolarHBondContact O-CG 3.48Å; P114-L116 VanDerWaalsContact C-N 3.34Å; P114-L116 PolarHBondContact O-N 2.89Å; P114-L117 PolarHBondContact O-N 3.27Å; P114-F118 WeakPolarHBondContact O-CB 3.2Å; P114-F118 WeakPolarHBondContact O-CD2 3.39Å; P114-F118 PolarHBondContact O-N 3.38Å; P114-A173 HydrophobicContact CG-CB 3.93Å; P114-S177 WeakPolarHBondContact CB-OG 3.34Å
115	S	94.6	Very high	92.9	Very high	25 Å²	25	49.7 Å²	49.7	18%	0.175	29%	0.285	C	S	.	.	H	α-helix	trans	-54.6	-47	176.3	-79.7	0	0	0	0	112.6	S111 T112 V113 L117 F118 L119 S176 T180	S111-S115 WeakPolarHBondContact O-CB 3.18Å; S111-S115 PolarHBondContact O-N 3.41Å; S111-S115 VanDerWaalsContact O-N 3.1Å; S111-S115 PolarHBondContact O-OG 3.37Å; T112-S115 PolarHBondContact O-N 3.14Å; V113-S115 PolarHBondContact O-N 3.27Å; S115-L117 PolarHBondContact O-N 2.62Å; S115-F118 PolarHBondContact O-N 2.9Å; S115-L119 VanDerWaalsContact O-CB 3.32Å; S115-L119 WeakPolarHBondContact O-CB 3.29Å; S115-L119 PolarHBondContact O-N 3.29Å; S115-S176 PolarHBondContact OG-O 3.44Å; S115-T180 VanDerWaalsContact CB-OG1 3.23Å; S115-T180 WeakPolarHBondContact CB-OG1 3.41Å; S115-T180 WeakPolarHBondContact O-CG2 3.38Å; S115-T180 PolarHBondContact OG-OG1 2.93Å
116	L	93.5	Very high	93.1	Very high	34 Å²	34	47 Å²	47	18%	0.178	27%	0.265	C	S	.	.	H	α-helix	trans	-62.7	-44.2	178.3	-74.5	172.7	0	0	0	112.4	T112 V113 P114 L119 V120 S458 M462	T112-L116 HydrophobicContact CG2-CD1 4.2Å; T112-L116 WeakPolarHBondContact O-CG 3.23Å; T112-L116 PolarHBondContact O-N 3.16Å; V113-L116 PolarHBondContact O-N 3.12Å; P114-L116 VanDerWaalsContact C-N 3.34Å; P114-L116 PolarHBondContact O-N 2.89Å; L116-L119 WeakPolarHBondContact O-CB 3.32Å; L116-L119 PolarHBondContact O-N 3Å; L116-V120 WeakPolarHBondContact O-CG2 3.28Å; L116-V120 PolarHBondContact O-N 3.49Å; L116-V120 VanDerWaalsContact O-N 3.15Å; L116-S458 VanDerWaalsContact CD2-CB 3.43Å; L116-M462 HydrophobicContact CD1-SD 3.69Å
117	L	95.5	Very high	93	Very high	116 Å²	116	45.7 Å²	45.7	61%	0.607	27%	0.265	S	S	*	.	H	α-helix	trans	-63.3	-43.9	178.1	-66.8	175.3	0	0	0	111.5	V113 P114 S115 L119 V120 A121	V113-L117 HydrophobicContact CG1-CD1 4.42Å; V113-L117 WeakPolarHBondContact O-CG 3.46Å; V113-L117 PolarHBondContact O-N 2.66Å; P114-L117 PolarHBondContact O-N 3.27Å; S115-L117 PolarHBondContact O-N 2.62Å; L117-L119 VanDerWaalsContact C-N 3.32Å; L117-L119 PolarHBondContact O-N 3.43Å; L117-V120 PolarHBondContact O-N 2.99Å; L117-A121 WeakPolarHBondContact O-CB 3.32Å; L117-A121 PolarHBondContact O-N 3.22Å
118	F	96.2	Very high	93	Very high	88 Å²	88	52.1 Å²	52.1	39%	0.386	29%	0.289	S	S	.	.	H	α-helix	trans	-72.7	-24.5	178.9	-87.2	-95.4	0	0	0	113.2	P114 S115 N122 S177 I181	P114-F118 WeakPolarHBondContact O-CB 3.2Å; P114-F118 WeakPolarHBondContact O-CD2 3.39Å; P114-F118 PolarHBondContact O-N 3.38Å; S115-F118 PolarHBondContact O-N 2.9Å; F118-N122 VanDerWaalsContact O-CB 3.3Å; F118-N122 WeakPolarHBondContact O-CB 3.22Å; F118-N122 PolarHBondContact O-N 2.87Å; F118-S177 WeakPolarHBondContact CD2-OG 3.32Å; F118-I181 HydrophobicContact CB-CG1 4.4Å; F118-I181 HydrophobicContact CD1-CD1 3.44Å; F118-I181 VanDerWaalsContact CD1-CD1 3.44Å; F118-I181 HydrophobicContact CD1-CG1 3.93Å; F118-I181 HydrophobicContact CE1-CD1 3.92Å
119	L	95.8	Very high	93.1	Very high	3 Å²	3	52 Å²	52	2%	0.016	28%	0.283	C	S	.	.	H	α-helix	trans	-66.9	-45	170.2	-174.7	57.4	0	0	0	111.2	S115 L116 L117 N122 F123 T180 V451 L454 F455	S115-L119 VanDerWaalsContact O-CB 3.32Å; S115-L119 WeakPolarHBondContact O-CB 3.29Å; S115-L119 PolarHBondContact O-N 3.29Å; L116-L119 WeakPolarHBondContact O-CB 3.32Å; L116-L119 PolarHBondContact O-N 3Å; L117-L119 VanDerWaalsContact C-N 3.32Å; L117-L119 PolarHBondContact O-N 3.43Å; L119-N122 PolarHBondContact O-N 3.48Å; L119-F123 PolarHBondContact O-N 3.48Å; L119-T180 HydrophobicContact CB-CG2 3.81Å; L119-T180 HydrophobicContact CD1-CG2 4.23Å; L119-V451 HydrophobicContact CD1-CG1 3.93Å; L119-L454 HydrophobicContact CD1-CB 4.25Å; L119-L454 HydrophobicContact CD2-CB 4.48Å; L119-F455 HydrophobicContact CD2-CB 4.09Å; L119-F455 HydrophobicContact CD2-CD2 4.3Å
120	V	95.5	Very high	93.2	Very high	68 Å²	68	54.9 Å²	54.9	41%	0.412	29%	0.291	S	S	.	.	H	α-helix	trans	-64	-44	173.4	176.4	0	0	0	0	110.5	L116 L117 N122 F123 L124 F455	L116-V120 WeakPolarHBondContact O-CG2 3.28Å; L116-V120 PolarHBondContact O-N 3.49Å; L116-V120 VanDerWaalsContact O-N 3.15Å; L117-V120 PolarHBondContact O-N 2.99Å; V120-N122 VanDerWaalsContact C-N 3.32Å; V120-N122 PolarHBondContact O-N 3.17Å; V120-F123 WeakPolarHBondContact O-CB 3.47Å; V120-F123 PolarHBondContact O-N 3.46Å; V120-L124 WeakPolarHBondContact O-CG 3.25Å; V120-L124 PolarHBondContact O-N 2.99Å; V120-L124 VanDerWaalsContact O-N 3.16Å; V120-F455 HydrophobicContact CG2-CD2 4.23Å; V120-F455 HydrophobicContact CG2-CE2 3.94Å
121	A	95.3	Very high	93.2	Very high	34 Å²	34	55.4 Å²	55.4	28%	0.281	29%	0.292	S	S	.	.	H	α-helix	trans	-59.1	-43.9	175.4	0	0	0	0	0	111.4	L117 F123 L124 L125	L117-A121 WeakPolarHBondContact O-CB 3.32Å; L117-A121 PolarHBondContact O-N 3.22Å; A121-F123 VanDerWaalsContact C-N 3.34Å; A121-F123 PolarHBondContact O-N 3.01Å; A121-L124 WeakPolarHBondContact O-CB 3.15Å; A121-L124 PolarHBondContact O-N 3.43Å; A121-L124 VanDerWaalsContact O-N 3.14Å; A121-L125 VanDerWaalsContact O-CG 3.28Å; A121-L125 WeakPolarHBondContact O-CG 3.4Å; A121-L125 PolarHBondContact O-N 2.92Å
122	N	95.3	Very high	93.1	Very high	1 Å²	1	58 Å²	58	1%	0.005	30%	0.304	C	S	.	.	H	α-helix	trans	-62	-41	178	-172	62.7	0	0	0	111.7	F118 L119 V120 L124 L125 V126 R134 S184 S185	F118-N122 VanDerWaalsContact O-CB 3.3Å; F118-N122 WeakPolarHBondContact O-CB 3.22Å; F118-N122 PolarHBondContact O-N 2.87Å; L119-N122 PolarHBondContact O-N 3.48Å; V120-N122 VanDerWaalsContact C-N 3.32Å; V120-N122 PolarHBondContact O-N 3.17Å; N122-L124 VanDerWaalsContact C-N 3.3Å; N122-L124 PolarHBondContact O-N 3.27Å; N122-L125 CarbonylContact O-C 3.55Å; N122-L125 PolarHBondContact O-N 3.31Å; N122-V126 WeakPolarHBondContact O-CG2 3.46Å; N122-V126 PolarHBondContact O-N 2.83Å; N122-R134 WeakPolarHBondContact OD1-CD 3.28Å; N122-R134 PolarHBondContact OD1-NE 3.32Å; N122-S184 PolarHBondContact ND2-OG 2.9Å; N122-S185 PolarHBondContact OD1-OG 3.35Å
123	F	94.5	Very high	93.3	Very high	18 Å²	18	58.9 Å²	58.9	8%	0.079	31%	0.309	C	S	.	.	H	α-helix	trans	-55.5	-44.3	173.2	175.9	-94	0	0	0	112.1	L119 V120 A121 L125 V126 P296 L298 A448 V451 V452	L119-F123 PolarHBondContact O-N 3.48Å; V120-F123 WeakPolarHBondContact O-CB 3.47Å; V120-F123 PolarHBondContact O-N 3.46Å; A121-F123 VanDerWaalsContact C-N 3.34Å; A121-F123 PolarHBondContact O-N 3.01Å; F123-L125 VanDerWaalsContact C-N 3.27Å; F123-L125 PolarHBondContact O-N 3.15Å; F123-V126 PolarHBondContact O-N 2.87Å; F123-P296 HydrophobicContact CE2-CB 4.08Å; F123-P296 HydrophobicContact CE2-CG 4.22Å; F123-P296 HydrophobicContact CZ-CB 3.81Å; F123-P296 HydrophobicContact CZ-CG 4.11Å; F123-L298 HydrophobicContact CE1-CB 4.19Å; F123-L298 HydrophobicContact CE1-CD1 4.05Å; F123-L298 HydrophobicContact CE2-CD1 4.17Å; F123-L298 HydrophobicContact CZ-CB 3.99Å; F123-L298 HydrophobicContact CZ-CD1 3.66Å; F123-L298 HydrophobicContact CZ-CG 4.37Å; F123-A448 HydrophobicContact CD2-CB 4.44Å; F123-A448 HydrophobicContact CE2-CB 3.97Å; F123-V451 HydrophobicContact CB-CG1 3.85Å; F123-V451 HydrophobicContact CD2-CB 4.46Å; F123-V451 HydrophobicContact CD2-CG1 4.4Å; F123-V452 HydrophobicContact CD2-CG2 3.83Å; F123-V452 HydrophobicContact CE2-CG2 3.55Å; F123-V452 HydrophobicContact CZ-CG2 4.46Å
124	L	93.8	Very high	93.5	Very high	86 Å²	86	55.8 Å²	55.8	45%	0.45	29%	0.289	S	S	.	.	H	α-helix	trans	-67.5	-28.6	177.6	-61.8	174	0	0	0	112.6	V120 A121 N122 T295	V120-L124 WeakPolarHBondContact O-CG 3.25Å; V120-L124 PolarHBondContact O-N 2.99Å; V120-L124 VanDerWaalsContact O-N 3.16Å; A121-L124 WeakPolarHBondContact O-CB 3.15Å; A121-L124 PolarHBondContact O-N 3.43Å; A121-L124 VanDerWaalsContact O-N 3.14Å; N122-L124 VanDerWaalsContact C-N 3.3Å; N122-L124 PolarHBondContact O-N 3.27Å; L124-T295 HydrophobicContact CD2-CG2 4.28Å
125	L	92	Very high	93.6	Very high	71 Å²	71	54.6 Å²	54.6	37%	0.372	28%	0.281	S	S	.	.	H	α-helix	trans	-84.9	-11.6	179.2	-66.4	173.4	0	0	0	113.9	A121 N122 F123 N127 R128 V129	A121-L125 VanDerWaalsContact O-CG 3.28Å; A121-L125 WeakPolarHBondContact O-CG 3.4Å; A121-L125 PolarHBondContact O-N 2.92Å; N122-L125 CarbonylContact O-C 3.55Å; N122-L125 PolarHBondContact O-N 3.31Å; F123-L125 VanDerWaalsContact C-N 3.27Å; F123-L125 PolarHBondContact O-N 3.15Å; L125-N127 VanDerWaalsContact C-N 3.3Å; L125-N127 PolarHBondContact O-N 3.45Å; L125-R128 PolarHBondContact O-N 2.95Å; L125-V129 HydrophobicContact CB-CG2 4.45Å; L125-V129 HydrophobicContact CD2-CG2 3.94Å; L125-V129 PolarHBondContact O-N 2.81Å
126	V	89.9	Confident	93.7	Very high	13 Å²	13	55.3 Å²	55.3	8%	0.079	28%	0.283	C	S	.	.	T	Hydrogen-bonded Turn	trans	-50	-48.7	-176.4	167.9	0	0	0	0	112.1	N122 F123 R134 P296 E447 A448 V451	N122-V126 WeakPolarHBondContact O-CG2 3.46Å; N122-V126 PolarHBondContact O-N 2.83Å; F123-V126 PolarHBondContact O-N 2.87Å; V126-R134 PolarHBondContact O-NH1 3.34Å; V126-P296 HydrophobicContact CB-CG 4.19Å; V126-P296 HydrophobicContact CG1-CG 4.34Å; V126-E447 HydrophobicContact CG1-CB 4.28Å; V126-E447 HydrophobicContact CG1-CG 3.78Å; V126-A448 HydrophobicContact CG1-CB 4.3Å; V126-V451 HydrophobicContact CG2-CG2 4.08Å
127	N	87.4	Confident	93.9	Very high	76 Å²	76	56.2 Å²	56.2	41%	0.406	30%	0.295	S	S	.	.	T	Hydrogen-bonded Turn	trans	-87.2	-6.1	-178.6	-68.9	5.6	0	0	0	113.7	L125 M293	L125-N127 VanDerWaalsContact C-N 3.3Å; L125-N127 PolarHBondContact O-N 3.45Å; N127-M293 PolarHBondContact ND2-O 3.42Å
128	R	89.6	Confident	93.9	Very high	145 Å²	145	50.9 Å²	50.9	55%	0.547	27%	0.268	S	S	.	.	T	Hydrogen-bonded Turn	trans	-105.8	-37.2	-171.6	-64.5	-65.7	-163.8	144.1	8.2	113.3	L125 H294	L125-R128 PolarHBondContact O-N 2.95Å; R128-H294 VanDerWaalsContact CZ-CB 3.4Å; R128-H294 VanDerWaalsContact CZ-ND1 3.31Å; R128-H294 PolarHBondContact NE-O 3.17Å; R128-H294 PolarHBondContact NH1-ND1 2.9Å; R128-H294 VanDerWaalsContact NH2-CB 3.25Å; R128-H294 VanDerWaalsContact NH2-CG 3.3Å
129	V	92.1	Very high	94	Very high	46 Å²	46	46.7 Å²	46.7	28%	0.279	25%	0.249	S	C	.	.	S	Bend	trans	-123.7	129.1	-174.5	-178.3	0	0	0	0	108.1	L125 V131 V133 R134	L125-V129 HydrophobicContact CB-CG2 4.45Å; L125-V129 HydrophobicContact CD2-CG2 3.94Å; L125-V129 PolarHBondContact O-N 2.81Å; V129-V131 PolarHBondContact O-N 2.93Å; V129-V133 HydrophobicContact CG1-CB 3.95Å; V129-V133 HydrophobicContact CG1-CG1 4.03Å; V129-R134 HydrophobicContact CB-CG 4.02Å; V129-R134 HydrophobicContact CG1-CG 3.61Å; V129-R134 PolarHBondContact O-NH1 3.23Å
130	Q	91.7	Very high	94	Very high	150 Å²	150	49.3 Å²	49.3	70%	0.701	27%	0.268	S	S	*	.			trans	-59.2	139	179.1	-64.7	179.9	-0.1	0	0	111.3	H132 V133 R134	Q130-H132 PolarHBondContact O-N 3.46Å; Q130-H132 VanDerWaalsContact O-N 3.08Å; Q130-V133 HydrophobicContact CB-CG2 4.45Å; Q130-V133 PolarHBondContact O-N 3.23Å; Q130-R134 PolarHBondContact O-N 3.24Å
131	V	92.8	Very high	94.1	Very high	22 Å²	22	49 Å²	49	13%	0.133	27%	0.266	C	S	.	.	H	α-helix	trans	-50.8	-36.5	178.4	66.8	0	0	0	0	112.6	V129 V133 R134 V135 L189	V129-V131 PolarHBondContact O-N 2.93Å; V131-V133 PolarHBondContact O-N 3.44Å; V131-R134 PolarHBondContact O-N 3.04Å; V131-V135 HydrophobicContact CG2-CG2 4.13Å; V131-V135 WeakPolarHBondContact O-CB 3.45Å; V131-V135 WeakPolarHBondContact O-CG2 3.28Å; V131-V135 PolarHBondContact O-N 3.09Å; V131-L189 HydrophobicContact CG1-CD1 4.25Å; V131-L189 HydrophobicContact CG2-CB 4.24Å
132	H	92.7	Very high	94.1	Very high	58 Å²	58	47.4 Å²	47.4	27%	0.269	25%	0.253	S	S	.	.	H	α-helix	trans	-62.1	-38.7	178.4	-160.4	-47.5	0	0	0	113.7	Q130 L136 Y248	Q130-H132 PolarHBondContact O-N 3.46Å; Q130-H132 VanDerWaalsContact O-N 3.08Å; H132-L136 WeakPolarHBondContact CE1-CD1 3.4Å; H132-L136 WeakPolarHBondContact ND1-CD1 3.3Å; H132-L136 WeakPolarHBondContact O-CB 3.3Å; H132-L136 WeakPolarHBondContact O-CG 3.46Å; H132-L136 PolarHBondContact O-N 3.31Å; H132-L136 VanDerWaalsContact O-N 3.14Å; H132-Y248 VanDerWaalsContact CA-OH 3.26Å; H132-Y248 WeakPolarHBondContact CA-OH 3.28Å; H132-Y248 HydrophobicContact CB-CE1 4.42Å; H132-Y248 AromaticContact CE1-CE1 3.96Å; H132-Y248 AromaticContact CG-CE1 3.85Å; H132-Y248 AromaticContact ND1-CE1 3.79Å
133	V	95.1	Very high	94.1	Very high	80 Å²	80	49.7 Å²	49.7	49%	0.485	27%	0.265	S	S	.	.	H	α-helix	trans	-71.2	-43.9	176.8	177.8	0	0	0	0	109.6	V129 Q130 V131 V135 A137	V129-V133 HydrophobicContact CG1-CB 3.95Å; V129-V133 HydrophobicContact CG1-CG1 4.03Å; Q130-V133 HydrophobicContact CB-CG2 4.45Å; Q130-V133 PolarHBondContact O-N 3.23Å; V131-V133 PolarHBondContact O-N 3.44Å; V133-V135 PolarHBondContact O-N 3.44Å; V133-A137 WeakPolarHBondContact O-CB 3.35Å; V133-A137 PolarHBondContact O-N 3.3Å
134	R	96	Very high	94.3	Very high	12 Å²	12	51.4 Å²	51.4	5%	0.045	28%	0.282	C	S	.	.	H	α-helix	trans	-61.9	-45.3	-179.8	-55.5	-168.5	-47.7	-111	3.2	111.9	N122 V126 V129 Q130 V131 S138 I181 S185 E447	N122-R134 WeakPolarHBondContact OD1-CD 3.28Å; N122-R134 PolarHBondContact OD1-NE 3.32Å; V126-R134 PolarHBondContact O-NH1 3.34Å; V129-R134 HydrophobicContact CB-CG 4.02Å; V129-R134 HydrophobicContact CG1-CG 3.61Å; V129-R134 PolarHBondContact O-NH1 3.23Å; Q130-R134 PolarHBondContact O-N 3.24Å; V131-R134 PolarHBondContact O-N 3.04Å; R134-S138 VanDerWaalsContact O-CB 3.32Å; R134-S138 WeakPolarHBondContact O-CB 3.34Å; R134-S138 PolarHBondContact O-N 3.47Å; R134-S138 VanDerWaalsContact O-N 3.14Å; R134-S138 PolarHBondContact O-OG 3.07Å; R134-I181 HydrophobicContact CB-CG2 4.09Å; R134-S185 WeakPolarHBondContact CB-OG 3.37Å; R134-S185 PolarHBondContact NE-OG 3.04Å; R134-E447 IonicContact CZ-OE1 3.48Å; R134-E447 IonicContact NH1-OE1 3.37Å; R134-E447 PolarHBondContact NH1-OE1 3.39Å; R134-E447 IonicContact NH2-OE1 2.66Å; R134-E447 PolarHBondContact NH2-OE1 3.41Å
135	V	96.2	Very high	94.4	Very high	0 Å²	0	48.5 Å²	48.5	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-66.8	-49.7	179.2	172	0	0	0	0	111.9	V131 V133 S138 L139 F182 V186 Y248	V131-V135 HydrophobicContact CG2-CG2 4.13Å; V131-V135 WeakPolarHBondContact O-CB 3.45Å; V131-V135 WeakPolarHBondContact O-CG2 3.28Å; V131-V135 PolarHBondContact O-N 3.09Å; V133-V135 PolarHBondContact O-N 3.44Å; V135-S138 PolarHBondContact O-OG 2.98Å; V135-L139 HydrophobicContact CG1-CD1 4.07Å; V135-L139 WeakPolarHBondContact O-CG 3.26Å; V135-L139 PolarHBondContact O-N 3.45Å; V135-L139 VanDerWaalsContact O-N 3.08Å; V135-F182 HydrophobicContact CG1-CD2 3.94Å; V135-F182 HydrophobicContact CG1-CE2 3.91Å; V135-V186 HydrophobicContact CG1-CG2 4.25Å; V135-V186 HydrophobicContact CG2-CG2 3.77Å; V135-Y248 HydrophobicContact CB-CD1 4.35Å; V135-Y248 HydrophobicContact CB-CD2 4.49Å; V135-Y248 HydrophobicContact CB-CE1 3.96Å; V135-Y248 HydrophobicContact CB-CE2 4.1Å; V135-Y248 HydrophobicContact CG1-CD1 3.7Å; V135-Y248 HydrophobicContact CG1-CD2 3.66Å; V135-Y248 HydrophobicContact CG1-CE1 3.82Å; V135-Y248 HydrophobicContact CG1-CE2 3.77Å; V135-Y248 HydrophobicContact CG1-CG 3.63Å; V135-Y248 HydrophobicContact CG2-CE2 4.08Å
136	L	96.9	Very high	94.5	Very high	41 Å²	41	45.1 Å²	45.1	22%	0.215	25%	0.249	C	C	.	.	H	α-helix	trans	-67.3	-42.8	-179.3	-74.4	-171.2	0	0	0	112.6	H132 S138 L139 S140 M245 Y248 L249	H132-L136 WeakPolarHBondContact CE1-CD1 3.4Å; H132-L136 WeakPolarHBondContact ND1-CD1 3.3Å; H132-L136 WeakPolarHBondContact O-CB 3.3Å; H132-L136 WeakPolarHBondContact O-CG 3.46Å; H132-L136 PolarHBondContact O-N 3.31Å; H132-L136 VanDerWaalsContact O-N 3.14Å; L136-S138 VanDerWaalsContact C-N 3.34Å; L136-S138 PolarHBondContact O-N 3.31Å; L136-L139 PolarHBondContact O-N 3.17Å; L136-S140 WeakPolarHBondContact O-CB 3.42Å; L136-S140 PolarHBondContact O-N 3.27Å; L136-S140 PolarHBondContact O-OG 3.03Å; L136-M245 HydrophobicContact CD2-CG 3.85Å; L136-Y248 HydrophobicContact CD2-CD1 3.97Å; L136-Y248 HydrophobicContact CG-CD1 4.31Å; L136-Y248 HydrophobicContact CG-CE1 4.44Å; L136-L249 HydrophobicContact CD1-CD2 4.05Å; L136-L249 HydrophobicContact CD2-CD2 4.18Å; L136-L249 HydrophobicContact CD2-CG 4.31Å
137	A	97	Very high	94.7	Very high	52 Å²	52	48.2 Å²	48.2	43%	0.43	27%	0.268	S	S	.	.	H	α-helix	trans	-61.1	-44.9	179.4	0	0	0	0	0	111.2	V133 S140 V141	V133-A137 WeakPolarHBondContact O-CB 3.35Å; V133-A137 PolarHBondContact O-N 3.3Å; A137-S140 PolarHBondContact O-N 2.87Å; A137-V141 VanDerWaalsContact O-CG2 3.29Å; A137-V141 WeakPolarHBondContact O-CG2 3.37Å; A137-V141 PolarHBondContact O-N 3.31Å
138	S	97	Very high	95.1	Very high	4 Å²	4	47.7 Å²	47.7	3%	0.028	27%	0.267	C	S	.	.	H	α-helix	trans	-64.6	-40.4	178.3	52.5	0	0	0	0	113.3	R134 V135 L136 S142 S178 F182	R134-S138 VanDerWaalsContact O-CB 3.32Å; R134-S138 WeakPolarHBondContact O-CB 3.34Å; R134-S138 PolarHBondContact O-N 3.47Å; R134-S138 VanDerWaalsContact O-N 3.14Å; R134-S138 PolarHBondContact O-OG 3.07Å; V135-S138 PolarHBondContact O-OG 2.98Å; L136-S138 VanDerWaalsContact C-N 3.34Å; L136-S138 PolarHBondContact O-N 3.31Å; S138-S142 WeakPolarHBondContact O-CB 3.44Å; S138-S142 PolarHBondContact O-N 3.16Å; S138-S142 PolarHBondContact O-OG 3.37Å; S138-S178 VanDerWaalsContact CB-O 3.24Å; S138-S178 WeakPolarHBondContact CB-O 3.42Å; S138-F182 WeakPolarHBondContact OG-CA 3.5Å; S138-F182 WeakPolarHBondContact OG-CB 3.46Å
139	L	96.5	Very high	95.3	Very high	1 Å²	1	40.8 Å²	40.8	1%	0.005	24%	0.241	C	C	.	.	H	α-helix	trans	-65.6	-43.2	173.8	-72.9	174.4	0	0	0	112.1	V135 L136 S142 L143 F182 L241 C244 M245	V135-L139 HydrophobicContact CG1-CD1 4.07Å; V135-L139 WeakPolarHBondContact O-CG 3.26Å; V135-L139 PolarHBondContact O-N 3.45Å; V135-L139 VanDerWaalsContact O-N 3.08Å; L136-L139 PolarHBondContact O-N 3.17Å; L139-S142 PolarHBondContact O-N 3.5Å; L139-L143 WeakPolarHBondContact O-CB 3.3Å; L139-L143 PolarHBondContact O-N 3.47Å; L139-F182 HydrophobicContact CD1-CD2 4.08Å; L139-F182 HydrophobicContact CD1-CE2 3.78Å; L139-F182 HydrophobicContact CD2-CD2 3.72Å; L139-F182 HydrophobicContact CD2-CE2 3.73Å; L139-F182 HydrophobicContact CD2-CG 4.13Å; L139-F182 HydrophobicContact CD2-CZ 4.14Å; L139-F182 HydrophobicContact CG-CD2 3.66Å; L139-F182 HydrophobicContact CG-CE2 3.82Å; L139-F182 HydrophobicContact CG-CG 4.42Å; L139-L241 HydrophobicContact CD2-CD2 3.79Å; L139-C244 HydrophobicContact CD1-CB 4.35Å; L139-C244 HydrophobicContact CD2-CB 4.2Å; L139-M245 HydrophobicContact CB-CE 3.88Å; L139-M245 HydrophobicContact CD1-CB 4.17Å
140	S	97.2	Very high	95.4	Very high	57 Å²	57	40 Å²	40	40%	0.399	24%	0.235	S	C	.	.	H	α-helix	trans	-61	-45.6	177.2	-65	0	0	0	0	112.1	L136 A137 L143 A144 M245	L136-S140 WeakPolarHBondContact O-CB 3.42Å; L136-S140 PolarHBondContact O-N 3.27Å; L136-S140 PolarHBondContact O-OG 3.03Å; A137-S140 PolarHBondContact O-N 2.87Å; S140-L143 PolarHBondContact O-N 3.35Å; S140-A144 WeakPolarHBondContact O-CB 3.28Å; S140-A144 PolarHBondContact O-N 3.11Å; S140-M245 WeakPolarHBondContact OG-CE 3.47Å
141	V	97	Very high	95.6	Very high	62 Å²	62	37 Å²	37	38%	0.376	23%	0.227	S	C	.	.	H	α-helix	trans	-63.4	-46.4	177.2	172.9	0	0	0	0	110.4	A137 L143 A144 I145 I174 S178	A137-V141 VanDerWaalsContact O-CG2 3.29Å; A137-V141 WeakPolarHBondContact O-CG2 3.37Å; A137-V141 PolarHBondContact O-N 3.31Å; V141-L143 VanDerWaalsContact C-N 3.34Å; V141-L143 PolarHBondContact O-N 3.1Å; V141-A144 PolarHBondContact O-N 3.3Å; V141-I145 WeakPolarHBondContact O-CG1 3.14Å; V141-I145 PolarHBondContact O-N 3.48Å; V141-I174 HydrophobicContact CG1-CG2 3.58Å; V141-S178 WeakPolarHBondContact CG1-OG 3.33Å
142	S	95.3	Very high	95.6	Very high	1 Å²	1	36.7 Å²	36.7	1%	0.007	22%	0.224	C	C	.	.	H	α-helix	trans	-59.1	-46	178.4	-55.7	0	0	0	0	111.3	S138 L139 A144 I145 F146 S178	S138-S142 WeakPolarHBondContact O-CB 3.44Å; S138-S142 PolarHBondContact O-N 3.16Å; S138-S142 PolarHBondContact O-OG 3.37Å; L139-S142 PolarHBondContact O-N 3.5Å; S142-A144 PolarHBondContact O-N 3.19Å; S142-I145 PolarHBondContact O-N 3.05Å; S142-F146 WeakPolarHBondContact O-CD2 3.14Å; S142-F146 PolarHBondContact O-N 3.03Å; S142-S178 VanDerWaalsContact OG-CB 3.27Å; S142-S178 WeakPolarHBondContact OG-CB 3.28Å
143	L	96.2	Very high	95.6	Very high	49 Å²	49	34 Å²	34	26%	0.257	21%	0.212	S	C	.	.	H	α-helix	trans	-61.6	-44	178.5	-176.8	63.3	0	0	0	111.6	L139 S140 V141 I145 F146 V147 A238 L241	L139-L143 WeakPolarHBondContact O-CB 3.3Å; L139-L143 PolarHBondContact O-N 3.47Å; S140-L143 PolarHBondContact O-N 3.35Å; V141-L143 VanDerWaalsContact C-N 3.34Å; V141-L143 PolarHBondContact O-N 3.1Å; L143-I145 PolarHBondContact O-N 3.36Å; L143-F146 PolarHBondContact O-N 2.82Å; L143-V147 WeakPolarHBondContact O-CG2 3.08Å; L143-V147 PolarHBondContact O-N 3.49Å; L143-A238 HydrophobicContact CD1-CB 3.91Å; L143-A238 WeakPolarHBondContact CD1-O 2.97Å; L143-L241 HydrophobicContact CD1-CB 4.21Å
144	A	97	Very high	95.4	Very high	54 Å²	54	35.1 Å²	35.1	45%	0.446	21%	0.21	S	C	.	.	H	α-helix	trans	-60.3	-43.2	177.8	0	0	0	0	0	112.1	S140 V141 S142 V147 V148	S140-A144 WeakPolarHBondContact O-CB 3.28Å; S140-A144 PolarHBondContact O-N 3.11Å; V141-A144 PolarHBondContact O-N 3.3Å; S142-A144 PolarHBondContact O-N 3.19Å; A144-V147 PolarHBondContact O-N 3.08Å; A144-V148 WeakPolarHBondContact O-CG2 3.43Å; A144-V148 PolarHBondContact O-N 3.49Å
145	I	95.9	Very high	95.2	Very high	25 Å²	25	37.4 Å²	37.4	13%	0.128	23%	0.226	C	C	.	.	H	α-helix	trans	-66.8	-40.8	177	-57.7	-61.5	0	0	0	111.2	V141 S142 L143 V147 V148 M149 C171 I174 I175	V141-I145 WeakPolarHBondContact O-CG1 3.14Å; V141-I145 PolarHBondContact O-N 3.48Å; S142-I145 PolarHBondContact O-N 3.05Å; L143-I145 PolarHBondContact O-N 3.36Å; I145-V147 VanDerWaalsContact C-N 3.29Å; I145-V147 PolarHBondContact O-N 3.43Å; I145-V148 WeakPolarHBondContact O-CB 3.25Å; I145-V148 PolarHBondContact O-N 2.88Å; I145-V148 VanDerWaalsContact O-N 3.12Å; I145-M149 HydrophobicContact CG2-CG 4.3Å; I145-M149 WeakPolarHBondContact O-CG 3.34Å; I145-M149 PolarHBondContact O-N 2.8Å; I145-C171 HydrophobicContact CG2-CB 3.65Å; I145-I174 HydrophobicContact CD1-CD1 4.33Å; I145-I174 HydrophobicContact CD1-CG2 4.1Å; I145-I174 HydrophobicContact CG1-CB 4.41Å; I145-I174 HydrophobicContact CG1-CG2 3.81Å; I145-I175 HydrophobicContact CB-CD1 4.14Å; I145-I175 HydrophobicContact CB-CG1 3.83Å; I145-I175 HydrophobicContact CG1-CG1 4.45Å; I145-I175 HydrophobicContact CG2-CD1 3.46Å; I145-I175 VanDerWaalsContact CG2-CD1 3.46Å; I145-I175 HydrophobicContact CG2-CG1 3.59Å
146	F	94.3	Very high	94.8	Very high	0 Å²	0	43 Å²	43	0%	0	26%	0.255	C	S	.	.	H	α-helix	trans	-61.1	-37.5	174.9	-91.1	-79.4	0	0	0	112.5	P67 S142 L143 M149 I150 I175 F234 A237 A238 L241	P67-F146 HydrophobicContact CB-CD2 4.34Å; P67-F146 HydrophobicContact CB-CE2 3.4Å; P67-F146 VanDerWaalsContact CB-CE2 3.4Å; P67-F146 HydrophobicContact CB-CZ 3.54Å; P67-F146 WeakPolarHBondContact O-CZ 3.27Å; S142-F146 WeakPolarHBondContact O-CD2 3.14Å; S142-F146 PolarHBondContact O-N 3.03Å; L143-F146 PolarHBondContact O-N 2.82Å; F146-M149 PolarHBondContact O-N 3.37Å; F146-I150 WeakPolarHBondContact O-CD1 3.48Å; F146-I150 VanDerWaalsContact O-CG1 3.22Å; F146-I150 WeakPolarHBondContact O-CG1 3.32Å; F146-I150 PolarHBondContact O-N 2.88Å; F146-I175 HydrophobicContact CD2-CD1 4.33Å; F146-I175 HydrophobicContact CE2-CD1 3.95Å; F146-I175 HydrophobicContact CE2-CG1 4.31Å; F146-I175 HydrophobicContact CE2-CG2 4.17Å; F146-I175 HydrophobicContact CZ-CD1 4.3Å; F146-F234 HydrophobicContact CD1-CB 4.14Å; F146-F234 HydrophobicContact CD1-CD1 4.26Å; F146-F234 HydrophobicContact CD1-CG 4.34Å; F146-F234 AromaticContact CE1-CD1 3.9Å; F146-F234 HydrophobicContact CE1-CD1 3.9Å; F146-F234 HydrophobicContact CE1-CG 4.43Å; F146-A237 HydrophobicContact CD1-CB 3.64Å; F146-A237 HydrophobicContact CE1-CB 3.41Å; F146-A237 VanDerWaalsContact CE1-CB 3.41Å; F146-A237 HydrophobicContact CE2-CB 4.38Å; F146-A237 HydrophobicContact CG-CB 4.23Å; F146-A237 HydrophobicContact CZ-CB 3.84Å; F146-A238 HydrophobicContact CB-CB 4.35Å; F146-L241 HydrophobicContact CD2-CD1 3.58Å; F146-L241 HydrophobicContact CE2-CD1 4.13Å; F146-L241 HydrophobicContact CG-CD1 4.31Å
147	V	95.5	Very high	94.3	Very high	77 Å²	77	41.1 Å²	41.1	47%	0.467	25%	0.246	S	C	.	.	H	α-helix	trans	-61.5	-44.1	172.7	172	0	0	0	0	111.3	L143 A144 I145 M149 I150 V151	L143-V147 WeakPolarHBondContact O-CG2 3.08Å; L143-V147 PolarHBondContact O-N 3.49Å; A144-V147 PolarHBondContact O-N 3.08Å; I145-V147 VanDerWaalsContact C-N 3.29Å; I145-V147 PolarHBondContact O-N 3.43Å; V147-M149 VanDerWaalsContact C-N 3.33Å; V147-M149 PolarHBondContact O-N 3.32Å; V147-I150 PolarHBondContact O-N 3.34Å; V147-V151 WeakPolarHBondContact O-CG2 3.35Å; V147-V151 PolarHBondContact O-N 3.06Å; V147-V151 VanDerWaalsContact O-N 3.14Å
148	V	95.1	Very high	93.6	Very high	65 Å²	65	41 Å²	41	39%	0.394	24%	0.241	S	C	.	.	H	α-helix	trans	-58.6	-46.1	174	172.5	0	0	0	0	110.9	A144 I145 I150 V151 L152	A144-V148 WeakPolarHBondContact O-CG2 3.43Å; A144-V148 PolarHBondContact O-N 3.49Å; I145-V148 WeakPolarHBondContact O-CB 3.25Å; I145-V148 PolarHBondContact O-N 2.88Å; I145-V148 VanDerWaalsContact O-N 3.12Å; V148-I150 PolarHBondContact O-N 3.21Å; V148-V151 PolarHBondContact O-N 2.91Å; V148-L152 HydrophobicContact CG1-CD1 3.91Å; V148-L152 HydrophobicContact CG1-CG 4.3Å; V148-L152 WeakPolarHBondContact O-CG 3.44Å; V148-L152 PolarHBondContact O-N 3.1Å
149	M	93.6	Very high	93	Very high	0 Å²	0	46 Å²	46	0%	0	28%	0.276	C	S	.	.	H	α-helix	trans	-63.4	-40	179.5	-65.9	-55.5	-56	0	0	112.5	F71 W78 I145 F146 V147 V151 L152 V153 C171 F234	F71-M149 HydrophobicContact CE2-CE 3.82Å; F71-M149 HydrophobicContact CE2-CG 4.09Å; F71-M149 HydrophobicContact CE2-SD 4.21Å; F71-M149 HydrophobicContact CZ-CE 4.11Å; W78-M149 HydrophobicContact CH2-CE 3.58Å; W78-M149 HydrophobicContact CZ3-CE 3.97Å; I145-M149 HydrophobicContact CG2-CG 4.3Å; I145-M149 WeakPolarHBondContact O-CG 3.34Å; I145-M149 PolarHBondContact O-N 2.8Å; F146-M149 PolarHBondContact O-N 3.37Å; V147-M149 VanDerWaalsContact C-N 3.33Å; V147-M149 PolarHBondContact O-N 3.32Å; M149-V151 VanDerWaalsContact C-N 3.29Å; M149-V151 PolarHBondContact O-N 3.01Å; M149-L152 PolarHBondContact O-N 2.72Å; M149-L152 HydrophobicContact SD-CD1 4.07Å; M149-V153 WeakPolarHBondContact O-CG2 3.43Å; M149-V153 PolarHBondContact O-N 3.43Å; M149-C171 HydrophobicContact SD-CB 3.98Å; M149-F234 HydrophobicContact CB-CD2 3.77Å; M149-F234 HydrophobicContact CB-CE2 3.84Å; M149-F234 HydrophobicContact CB-CG 4.49Å; M149-F234 HydrophobicContact CE-CE2 4.03Å; M149-F234 HydrophobicContact CE-CZ 4.32Å
150	I	95	Very high	92.5	Very high	30 Å²	30	50.7 Å²	50.7	15%	0.154	29%	0.294	C	S	.	.	H	α-helix	trans	-57.9	-43.4	174.3	-70.9	160.5	0	0	0	110.8	F146 V147 V148 L231 F234 L235 A238	F146-I150 WeakPolarHBondContact O-CD1 3.48Å; F146-I150 VanDerWaalsContact O-CG1 3.22Å; F146-I150 WeakPolarHBondContact O-CG1 3.32Å; F146-I150 PolarHBondContact O-N 2.88Å; V147-I150 PolarHBondContact O-N 3.34Å; V148-I150 PolarHBondContact O-N 3.21Å; I150-L231 HydrophobicContact CG2-CD1 4.04Å; I150-F234 HydrophobicContact CD1-CB 4.44Å; I150-F234 HydrophobicContact CG1-CB 3.64Å; I150-L235 HydrophobicContact CD1-CD2 3.88Å; I150-L235 HydrophobicContact CD1-CG 4.29Å; I150-L235 HydrophobicContact CG1-CD2 4.48Å; I150-L235 HydrophobicContact CG2-CD2 4.39Å; I150-A238 HydrophobicContact CD1-CB 4.04Å
151	V	95.1	Very high	91.9	Very high	87 Å²	87	49 Å²	49	53%	0.527	28%	0.281	S	S	.	.	H	α-helix	trans	-65.1	-45.7	176.8	175.6	0	0	0	0	110.7	V147 V148 M149 V153 K154 V155	V147-V151 WeakPolarHBondContact O-CG2 3.35Å; V147-V151 PolarHBondContact O-N 3.06Å; V147-V151 VanDerWaalsContact O-N 3.14Å; V148-V151 PolarHBondContact O-N 2.91Å; M149-V151 VanDerWaalsContact C-N 3.29Å; M149-V151 PolarHBondContact O-N 3.01Å; V151-V153 VanDerWaalsContact C-N 3.26Å; V151-V153 PolarHBondContact O-N 3.13Å; V151-K154 PolarHBondContact O-N 3.07Å; V151-V155 HydrophobicContact CG1-CG2 4.21Å; V151-V155 WeakPolarHBondContact O-CG2 3.17Å; V151-V155 PolarHBondContact O-N 3.29Å
152	L	93.3	Very high	91.3	Very high	16 Å²	16	53.8 Å²	53.8	8%	0.084	29%	0.293	C	S	.	.	H	α-helix	trans	-63.1	-27.1	-178.6	-70.5	174.9	0	0	0	114	K81 V148 M149 K154 V155 W160 F164 L167	K81-L152 PolarHBondContact NZ-O 3.2Å; V148-L152 HydrophobicContact CG1-CD1 3.91Å; V148-L152 HydrophobicContact CG1-CG 4.3Å; V148-L152 WeakPolarHBondContact O-CG 3.44Å; V148-L152 PolarHBondContact O-N 3.1Å; M149-L152 PolarHBondContact O-N 2.72Å; M149-L152 HydrophobicContact SD-CD1 4.07Å; L152-K154 PolarHBondContact O-N 3.04Å; L152-V155 PolarHBondContact O-N 3.27Å; L152-W160 HydrophobicContact CD2-CH2 4.45Å; L152-F164 HydrophobicContact CB-CE2 4.27Å; L152-F164 HydrophobicContact CD1-CE2 4.47Å; L152-L167 HydrophobicContact CD1-CD2 3.68Å; L152-L167 HydrophobicContact CD1-CG 4.31Å; L152-L167 HydrophobicContact CD2-CD2 4.25Å
153	V	92.8	Very high	91	Very high	0 Å²	0	55.3 Å²	55.3	0%	0	31%	0.308	C	S	.	.	H	α-helix	trans	-60.9	-32.7	172.9	171	0	0	0	0	111.8	Y77 M149 V151 R227 T230 L231 F234	Y77-V153 HydrophobicContact CE1-CG2 4.39Å; Y77-V153 HydrophobicContact CE2-CB 4.41Å; Y77-V153 HydrophobicContact CE2-CG1 4.24Å; Y77-V153 HydrophobicContact CE2-CG2 4.03Å; Y77-V153 WeakPolarHBondContact OH-CA 3.15Å; M149-V153 WeakPolarHBondContact O-CG2 3.43Å; M149-V153 PolarHBondContact O-N 3.43Å; V151-V153 VanDerWaalsContact C-N 3.26Å; V151-V153 PolarHBondContact O-N 3.13Å; V153-R227 HydrophobicContact CG1-CB 4.33Å; V153-R227 WeakPolarHBondContact CG1-O 3.33Å; V153-R227 PolarHBondContact O-NE 3.24Å; V153-R227 PolarHBondContact O-NH2 3.38Å; V153-T230 HydrophobicContact CG2-CG2 3.91Å; V153-L231 HydrophobicContact CB-CD1 4.22Å; V153-L231 HydrophobicContact CG1-CB 4.21Å; V153-L231 HydrophobicContact CG1-CD1 4.02Å; V153-F234 HydrophobicContact CG2-CD2 3.69Å; V153-F234 HydrophobicContact CG2-CE2 3.67Å
154	K	90	Very high	90.8	Very high	105 Å²	105	53 Å²	53	46%	0.457	30%	0.296	S	S	.	.	H	α-helix	trans	-91.2	-24.7	-179	-66.4	-64.4	-173.1	-175.9	0	113.8	V151 L152 R227 D228 L231	V151-K154 PolarHBondContact O-N 3.07Å; L152-K154 PolarHBondContact O-N 3.04Å; K154-R227 PolarHBondContact O-NH2 2.66Å; K154-D228 IonicContact NZ-OD1 3Å; K154-D228 PolarHBondContact NZ-OD1 3.37Å; K154-L231 HydrophobicContact CG-CD1 4.3Å
155	V	91.8	Very high	90.4	Very high	60 Å²	60	51.9 Å²	51.9	36%	0.364	28%	0.281	S	S	.	.	S	Bend	trans	-71.1	137.6	177.4	174.9	0	0	0	0	111.1	K81 V151 L152 T157	K81-V155 PolarHBondContact NZ-O 3.47Å; V151-V155 HydrophobicContact CG1-CG2 4.21Å; V151-V155 WeakPolarHBondContact O-CG2 3.17Å; V151-V155 PolarHBondContact O-N 3.29Å; L152-V155 PolarHBondContact O-N 3.27Å; V155-T157 HydrophobicContact CG1-CG2 4.39Å
156	D	87.9	Confident	90.2	Very high	117 Å²	117	54 Å²	54	63%	0.626	30%	0.299	S	S	*	.			trans	-77	125.6	169.5	-171.7	9.5	0	0	0	110.3	S158	D156-S158 VanDerWaalsContact CG-OG 3.25Å; D156-S158 VanDerWaalsContact OD1-CB 3.3Å; D156-S158 WeakPolarHBondContact OD1-CB 3.13Å; D156-S158 PolarHBondContact OD1-N 3Å; D156-S158 PolarHBondContact OD1-OG 3.08Å; D156-S158 PolarHBondContact OD2-OG 3.17Å
157	T	86.1	Confident	90.2	Very high	2 Å²	2	57 Å²	57	1%	0.012	31%	0.314	C	S	.	.			trans	-114.6	6.3	-175	52.5	0	0	0	0	112.3	K81 V155 S159 W160 T161 F164	K81-T157 WeakPolarHBondContact CD-OG1 3.49Å; K81-T157 PolarHBondContact NZ-OG1 2.9Å; K81-T157 VanDerWaalsContact NZ-OG1 3.1Å; V155-T157 HydrophobicContact CG1-CG2 4.39Å; T157-S159 PolarHBondContact O-N 3Å; T157-W160 HydrophobicContact CG2-CZ2 3.88Å; T157-W160 CarbonylContact O-C 3.43Å; T157-W160 PolarHBondContact O-N 3.42Å; T157-T161 PolarHBondContact O-N 3.31Å; T157-F164 HydrophobicContact CG2-CB 4.11Å; T157-F164 HydrophobicContact CG2-CD2 3.71Å; T157-F164 HydrophobicContact CG2-CE2 4.4Å; T157-F164 HydrophobicContact CG2-CG 4Å
158	S	82.4	Confident	90.1	Very high	48 Å²	48	53.3 Å²	53.3	34%	0.336	29%	0.292	S	S	.	.	T	Hydrogen-bonded Turn	trans	-55.4	-31.1	-178	57.9	0	0	0	0	114.1	D156	D156-S158 VanDerWaalsContact CG-OG 3.25Å; D156-S158 VanDerWaalsContact OD1-CB 3.3Å; D156-S158 WeakPolarHBondContact OD1-CB 3.13Å; D156-S158 PolarHBondContact OD1-N 3Å; D156-S158 PolarHBondContact OD1-OG 3.08Å; D156-S158 PolarHBondContact OD2-OG 3.17Å
159	S	84.2	Confident	90	Very high	110 Å²	110	52 Å²	52	77%	0.769	28%	0.282	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82.6	-15.1	179.3	58.6	0	0	0	0	114.6	T157	T157-S159 PolarHBondContact O-N 3Å
160	W	87.8	Confident	90.1	Very high	100 Å²	100	54.1 Å²	54.1	38%	0.379	30%	0.3	S	S	.	.			trans	-143.5	41.5	-172.4	66	-67.8	0	0	0	112.6	L152 T157 R162 G163 F164 L167	L152-W160 HydrophobicContact CD2-CH2 4.45Å; T157-W160 HydrophobicContact CG2-CZ2 3.88Å; T157-W160 CarbonylContact O-C 3.43Å; T157-W160 PolarHBondContact O-N 3.42Å; W160-R162 VanDerWaalsContact C-N 3.28Å; W160-R162 PolarHBondContact O-N 3.23Å; W160-G163 WeakPolarHBondContact O-CA 3.44Å; W160-G163 PolarHBondContact O-N 2.91Å; W160-F164 PolarHBondContact O-N 2.9Å; W160-L167 HydrophobicContact CH2-CD2 4.09Å; W160-L167 HydrophobicContact CZ3-CD2 4.41Å
161	T	84.3	Confident	90.1	Very high	20 Å²	20	53 Å²	53	12%	0.123	29%	0.294	C	S	.	.	H	α-helix	trans	-50.6	-42.7	-176.7	-48.7	0	0	0	0	113.4	L82 T157 G163 F164 F165	L82-T161 HydrophobicContact CD2-CG2 4.12Å; T157-T161 PolarHBondContact O-N 3.31Å; T161-G163 PolarHBondContact O-N 3.48Å; T161-F164 PolarHBondContact O-N 2.87Å; T161-F165 WeakPolarHBondContact O-CB 3.32Å; T161-F165 PolarHBondContact O-N 2.8Å
162	R	84	Confident	90.1	Very high	164 Å²	164	48.8 Å²	48.8	62%	0.619	27%	0.269	S	S	*	.	H	α-helix	trans	-64	-37.7	176.5	-77.8	-174.7	-86.5	162	-8.5	113.4	I99 W160 S166	I99-R162 HydrophobicContact CD1-CG 4.37Å; W160-R162 VanDerWaalsContact C-N 3.28Å; W160-R162 PolarHBondContact O-N 3.23Å; R162-S166 PolarHBondContact O-N 3.05Å; R162-S166 PolarHBondContact O-OG 3.4Å
163	G	89.7	Confident	90.2	Very high	32 Å²	32	49.2 Å²	49.2	33%	0.33	28%	0.275	S	S	.	.	H	α-helix	trans	-69.4	-40.1	174.7	0	0	0	0	0	111.7	W160 T161 S166 L167	W160-G163 WeakPolarHBondContact O-CA 3.44Å; W160-G163 PolarHBondContact O-N 2.91Å; T161-G163 PolarHBondContact O-N 3.48Å; G163-S166 PolarHBondContact O-N 3.47Å; G163-L167 VanDerWaalsContact O-CB 3.28Å; G163-L167 WeakPolarHBondContact O-CB 3.41Å; G163-L167 PolarHBondContact O-N 3.02Å
164	F	90.6	Very high	90.3	Very high	1 Å²	1	52.7 Å²	52.7	0%	0.004	29%	0.292	C	S	.	.	H	α-helix	trans	-62.6	-43	172.9	173.5	-101.9	0	0	0	112.3	Y77 W78 K81 L82 L152 T157 W160 T161 L167 T168	Y77-F164 HydrophobicContact CE1-CZ 4.34Å; W78-F164 HydrophobicContact CZ3-CZ 4.13Å; K81-F164 HydrophobicContact CB-CD1 4.3Å; K81-F164 HydrophobicContact CB-CE1 3.6Å; K81-F164 HydrophobicContact CB-CZ 4.16Å; K81-F164 HydrophobicContact CD-CZ 4.48Å; K81-F164 HydrophobicContact CG-CE1 4.07Å; K81-F164 HydrophobicContact CG-CZ 4.12Å; L82-F164 HydrophobicContact CD2-CD1 4.17Å; L82-F164 HydrophobicContact CD2-CE1 4.5Å; L152-F164 HydrophobicContact CB-CE2 4.27Å; L152-F164 HydrophobicContact CD1-CE2 4.47Å; T157-F164 HydrophobicContact CG2-CB 4.11Å; T157-F164 HydrophobicContact CG2-CD2 3.71Å; T157-F164 HydrophobicContact CG2-CE2 4.4Å; T157-F164 HydrophobicContact CG2-CG 4Å; W160-F164 PolarHBondContact O-N 2.9Å; T161-F164 PolarHBondContact O-N 2.87Å; F164-L167 PolarHBondContact O-N 3.17Å; F164-T168 WeakPolarHBondContact O-CB 3.3Å; F164-T168 PolarHBondContact O-N 2.88Å; F164-T168 PolarHBondContact O-OG1 3.47Å
165	F	89.8	Confident	90.5	Very high	30 Å²	30	47.7 Å²	47.7	13%	0.132	27%	0.271	C	S	.	.	H	α-helix	trans	-57.7	-53.9	174.2	169.3	-102	0	0	0	111	L82 I99 F103 Y106 T161 L167 T168 I169	L82-F165 HydrophobicContact CD2-CB 3.87Å; L82-F165 HydrophobicContact CD2-CD2 4.28Å; I99-F165 HydrophobicContact CG2-CD2 3.6Å; I99-F165 HydrophobicContact CG2-CE2 3.87Å; I99-F165 HydrophobicContact CG2-CG 4.02Å; I99-F165 HydrophobicContact CG2-CZ 4.48Å; F103-F165 AromaticContact CD2-CD2 3.79Å; F103-F165 HydrophobicContact CD2-CD2 3.79Å; F103-F165 AromaticContact CD2-CE2 3.63Å; F103-F165 HydrophobicContact CD2-CE2 3.63Å; F103-F165 AromaticContact CE2-CD2 3.74Å; F103-F165 HydrophobicContact CE2-CD2 3.74Å; F103-F165 AromaticContact CE2-CE2 3.84Å; F103-F165 HydrophobicContact CE2-CE2 3.84Å; Y106-F165 HydrophobicContact CD2-CE2 4.19Å; Y106-F165 AromaticContact CD2-CZ 3.89Å; Y106-F165 HydrophobicContact CD2-CZ 3.89Å; Y106-F165 HydrophobicContact CE2-CZ 4.37Å; Y106-F165 HydrophobicContact CG-CZ 4.07Å; T161-F165 WeakPolarHBondContact O-CB 3.32Å; T161-F165 PolarHBondContact O-N 2.8Å; F165-L167 VanDerWaalsContact C-N 3.3Å; F165-L167 PolarHBondContact O-N 3.3Å; F165-T168 WeakPolarHBondContact O-CB 3.43Å; F165-T168 PolarHBondContact O-N 3.38Å; F165-T168 VanDerWaalsContact O-N 3.09Å; F165-I169 HydrophobicContact CD2-CG1 4.19Å; F165-I169 HydrophobicContact CE1-CG1 4.18Å; F165-I169 HydrophobicContact CE2-CD1 3.94Å; F165-I169 HydrophobicContact CE2-CG1 3.73Å; F165-I169 HydrophobicContact CZ-CD1 4.22Å; F165-I169 HydrophobicContact CZ-CG1 3.74Å; F165-I169 WeakPolarHBondContact O-CG1 3.5Å; F165-I169 PolarHBondContact O-N 3.49Å
166	S	91.4	Very high	90.6	Very high	71 Å²	71	44.8 Å²	44.8	50%	0.497	25%	0.253	S	S	.	.	H	α-helix	trans	-59.2	-41.8	-179.4	-57.4	0	0	0	0	112.1	R162 G163 A170	R162-S166 PolarHBondContact O-N 3.05Å; R162-S166 PolarHBondContact O-OG 3.4Å; G163-S166 PolarHBondContact O-N 3.47Å; S166-A170 WeakPolarHBondContact O-CB 3.13Å; S166-A170 PolarHBondContact O-N 3.01Å
167	L	93.9	Very high	91	Very high	61 Å²	61	39.6 Å²	39.6	32%	0.319	23%	0.226	S	C	.	.	H	α-helix	trans	-63.8	-43.2	175.6	-179.4	59.9	0	0	0	111.7	L152 W160 G163 F164 F165 A170 C171	L152-L167 HydrophobicContact CD1-CD2 3.68Å; L152-L167 HydrophobicContact CD1-CG 4.31Å; L152-L167 HydrophobicContact CD2-CD2 4.25Å; W160-L167 HydrophobicContact CH2-CD2 4.09Å; W160-L167 HydrophobicContact CZ3-CD2 4.41Å; G163-L167 VanDerWaalsContact O-CB 3.28Å; G163-L167 WeakPolarHBondContact O-CB 3.41Å; G163-L167 PolarHBondContact O-N 3.02Å; F164-L167 PolarHBondContact O-N 3.17Å; F165-L167 VanDerWaalsContact C-N 3.3Å; F165-L167 PolarHBondContact O-N 3.3Å; L167-A170 PolarHBondContact O-N 2.84Å; L167-C171 WeakPolarHBondContact O-CB 3.27Å; L167-C171 PolarHBondContact O-N 3.44Å; L167-C171 PolarHBondContact O-SG 2.9Å
168	T	93.3	Very high	91.4	Very high	1 Å²	1	40 Å²	40	1%	0.006	23%	0.229	C	C	.	.	H	α-helix	trans	-62.6	-44.6	178.8	-60.3	0	0	0	0	111.3	F71 W78 F103 F164 F165 C171 M172	F71-T168 HydrophobicContact CE1-CG2 4.32Å; F71-T168 HydrophobicContact CZ-CG2 3.9Å; W78-T168 HydrophobicContact CE3-CG2 4.03Å; W78-T168 HydrophobicContact CH2-CG2 3.88Å; W78-T168 HydrophobicContact CZ3-CG2 3.45Å; W78-T168 VanDerWaalsContact CZ3-CG2 3.45Å; F103-T168 HydrophobicContact CZ-CG2 4.1Å; F164-T168 WeakPolarHBondContact O-CB 3.3Å; F164-T168 PolarHBondContact O-N 2.88Å; F164-T168 PolarHBondContact O-OG1 3.47Å; F165-T168 WeakPolarHBondContact O-CB 3.43Å; F165-T168 PolarHBondContact O-N 3.38Å; F165-T168 VanDerWaalsContact O-N 3.09Å; T168-C171 PolarHBondContact O-N 2.83Å; T168-M172 WeakPolarHBondContact O-CB 3.4Å; T168-M172 PolarHBondContact O-N 3.33Å
169	I	93.8	Very high	92	Very high	36 Å²	36	38.1 Å²	38.1	19%	0.185	22%	0.216	C	C	.	.	H	α-helix	trans	-62	-43.3	175.4	-65	-55.1	0	0	0	111	F103 L107 A110 F165 M172 A173	F103-I169 HydrophobicContact CE2-CD1 4.25Å; L107-I169 HydrophobicContact CD2-CD1 3.93Å; L107-I169 HydrophobicContact CG-CD1 4.41Å; A110-I169 HydrophobicContact CB-CG2 3.79Å; F165-I169 HydrophobicContact CD2-CG1 4.19Å; F165-I169 HydrophobicContact CE1-CG1 4.18Å; F165-I169 HydrophobicContact CE2-CD1 3.94Å; F165-I169 HydrophobicContact CE2-CG1 3.73Å; F165-I169 HydrophobicContact CZ-CD1 4.22Å; F165-I169 HydrophobicContact CZ-CG1 3.74Å; F165-I169 WeakPolarHBondContact O-CG1 3.5Å; F165-I169 PolarHBondContact O-N 3.49Å; I169-M172 PolarHBondContact O-N 2.76Å; I169-A173 PolarHBondContact O-N 2.96Å
170	A	95.7	Very high	92.6	Very high	46 Å²	46	33.9 Å²	33.9	38%	0.38	19%	0.185	S	C	.	.	H	α-helix	trans	-63	-44.1	175.6	0	0	0	0	0	112.2	S166 L167 M172 A173 I174	S166-A170 WeakPolarHBondContact O-CB 3.13Å; S166-A170 PolarHBondContact O-N 3.01Å; L167-A170 PolarHBondContact O-N 2.84Å; A170-M172 VanDerWaalsContact C-N 3.33Å; A170-M172 PolarHBondContact O-N 2.6Å; A170-A173 PolarHBondContact O-N 3.41Å; A170-I174 WeakPolarHBondContact O-CG1 3.11Å; A170-I174 PolarHBondContact O-N 2.8Å
171	C	94.8	Very high	92.9	Very high	5 Å²	5	30.8 Å²	30.8	3%	0.034	18%	0.176	C	C	.	.	H	α-helix	trans	-60	-42.4	174.7	-73.7	0	0	0	0	111.6	I145 M149 L167 T168 A173 I174 I175	I145-C171 HydrophobicContact CG2-CB 3.65Å; M149-C171 HydrophobicContact SD-CB 3.98Å; L167-C171 WeakPolarHBondContact O-CB 3.27Å; L167-C171 PolarHBondContact O-N 3.44Å; L167-C171 PolarHBondContact O-SG 2.9Å; T168-C171 PolarHBondContact O-N 2.83Å; C171-A173 PolarHBondContact O-N 3.21Å; C171-I174 PolarHBondContact O-N 3.18Å; C171-I175 WeakPolarHBondContact O-CB 3.35Å; C171-I175 WeakPolarHBondContact O-CG1 3.33Å; C171-I175 PolarHBondContact O-N 2.96Å
172	M	93.8	Very high	93.5	Very high	0 Å²	0	30 Å²	30	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-62.1	-42.4	177	-172.6	61.7	172.8	0	0	112	W68 F71 V72 L107 T168 I169 A170 S176	W68-M172 HydrophobicContact CG-CE 4.47Å; F71-M172 HydrophobicContact CD1-CE 4.23Å; F71-M172 HydrophobicContact CD1-SD 3.46Å; F71-M172 WeakPolarHBondContact CD1-SD 3.38Å; F71-M172 HydrophobicContact CE1-CB 4.28Å; F71-M172 HydrophobicContact CE1-CG 4.39Å; F71-M172 HydrophobicContact CE1-SD 3.65Å; F71-M172 HydrophobicContact CG-SD 4.02Å; F71-M172 HydrophobicContact CZ-CB 4.45Å; F71-M172 HydrophobicContact CZ-SD 4.32Å; V72-M172 HydrophobicContact CG2-CE 3.84Å; L107-M172 HydrophobicContact CD2-CB 3.86Å; L107-M172 HydrophobicContact CD2-CG 3.73Å; L107-M172 HydrophobicContact CD2-SD 4.43Å; T168-M172 WeakPolarHBondContact O-CB 3.4Å; T168-M172 PolarHBondContact O-N 3.33Å; I169-M172 PolarHBondContact O-N 2.76Å; A170-M172 VanDerWaalsContact C-N 3.33Å; A170-M172 PolarHBondContact O-N 2.6Å; M172-S176 VanDerWaalsContact O-CB 3.27Å; M172-S176 WeakPolarHBondContact O-CB 3.14Å; M172-S176 PolarHBondContact O-N 3.28Å; M172-S176 PolarHBondContact O-OG 2.97Å
173	A	95.7	Very high	94	Very high	24 Å²	24	23.5 Å²	23.5	20%	0.198	15%	0.148	C	C	.	.	H	α-helix	trans	-62.3	-43.5	176	0	0	0	0	0	112.2	A110 P114 I169 A170 C171 S177	A110-A173 WeakPolarHBondContact O-CA 3.49Å; A110-A173 WeakPolarHBondContact O-CB 3.46Å; P114-A173 HydrophobicContact CG-CB 3.93Å; I169-A173 PolarHBondContact O-N 2.96Å; A170-A173 PolarHBondContact O-N 3.41Å; C171-A173 PolarHBondContact O-N 3.21Å; A173-S177 VanDerWaalsContact O-CB 3.27Å; A173-S177 WeakPolarHBondContact O-CB 3.39Å; A173-S177 PolarHBondContact O-N 3.4Å; A173-S177 PolarHBondContact O-OG 2.83Å
174	I	95.5	Very high	94.3	Very high	73 Å²	73	22 Å²	22	37%	0.374	13%	0.133	S	C	.	.	H	α-helix	trans	-68.3	-44.9	179	-64.6	166.4	0	0	0	111.4	V141 I145 A170 C171 S177 S178	V141-I174 HydrophobicContact CG1-CG2 3.58Å; I145-I174 HydrophobicContact CD1-CD1 4.33Å; I145-I174 HydrophobicContact CD1-CG2 4.1Å; I145-I174 HydrophobicContact CG1-CB 4.41Å; I145-I174 HydrophobicContact CG1-CG2 3.81Å; A170-I174 WeakPolarHBondContact O-CG1 3.11Å; A170-I174 PolarHBondContact O-N 2.8Å; C171-I174 PolarHBondContact O-N 3.18Å; I174-S177 PolarHBondContact O-N 3.3Å; I174-S178 VanDerWaalsContact O-CB 3.29Å; I174-S178 WeakPolarHBondContact O-CB 3.39Å; I174-S178 PolarHBondContact O-N 2.94Å; I174-S178 PolarHBondContact O-OG 2.97Å
175	I	94.2	Very high	94.6	Very high	0 Å²	0	22 Å²	22	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-59.2	-52.4	175.9	-73.7	164.6	0	0	0	109.4	F71 I145 F146 C171 S177 S178 S179	F71-I175 HydrophobicContact CD2-CD1 4.09Å; F71-I175 HydrophobicContact CE2-CD1 4.1Å; I145-I175 HydrophobicContact CB-CD1 4.14Å; I145-I175 HydrophobicContact CB-CG1 3.83Å; I145-I175 HydrophobicContact CG1-CG1 4.45Å; I145-I175 HydrophobicContact CG2-CD1 3.46Å; I145-I175 VanDerWaalsContact CG2-CD1 3.46Å; I145-I175 HydrophobicContact CG2-CG1 3.59Å; F146-I175 HydrophobicContact CD2-CD1 4.33Å; F146-I175 HydrophobicContact CE2-CD1 3.95Å; F146-I175 HydrophobicContact CE2-CG1 4.31Å; F146-I175 HydrophobicContact CE2-CG2 4.17Å; F146-I175 HydrophobicContact CZ-CD1 4.3Å; C171-I175 WeakPolarHBondContact O-CB 3.35Å; C171-I175 WeakPolarHBondContact O-CG1 3.33Å; C171-I175 PolarHBondContact O-N 2.96Å; I175-S177 VanDerWaalsContact C-N 3.32Å; I175-S177 PolarHBondContact O-N 2.78Å; I175-S178 PolarHBondContact O-N 2.98Å; I175-S179 WeakPolarHBondContact O-CB 3.41Å; I175-S179 PolarHBondContact O-N 2.75Å; I175-S179 PolarHBondContact O-OG 3.26Å; I175-S179 VanDerWaalsContact O-OG 3.09Å
176	S	94.6	Very high	94.9	Very high	0 Å²	0	20.6 Å²	20.6	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-62.5	-40.4	-176.4	-55.7	0	0	0	0	111.8	S111 S115 M172 T180	S111-S176 WeakPolarHBondContact CA-OG 3.38Å; S111-S176 WeakPolarHBondContact CB-OG 3.32Å; S115-S176 PolarHBondContact OG-O 3.44Å; M172-S176 VanDerWaalsContact O-CB 3.27Å; M172-S176 WeakPolarHBondContact O-CB 3.14Å; M172-S176 PolarHBondContact O-N 3.28Å; M172-S176 PolarHBondContact O-OG 2.97Å; S176-T180 WeakPolarHBondContact O-CB 3.27Å; S176-T180 PolarHBondContact O-N 3.37Å; S176-T180 PolarHBondContact O-OG1 3.14Å
177	S	95.3	Very high	95.1	Very high	7 Å²	7	18.6 Å²	18.6	5%	0.049	11%	0.109	C	C	.	.	H	α-helix	trans	-62.6	-47.2	174.8	-59.2	0	0	0	0	111.8	P114 F118 A173 I174 I175 T180 I181	P114-S177 WeakPolarHBondContact CB-OG 3.34Å; F118-S177 WeakPolarHBondContact CD2-OG 3.32Å; A173-S177 VanDerWaalsContact O-CB 3.27Å; A173-S177 WeakPolarHBondContact O-CB 3.39Å; A173-S177 PolarHBondContact O-N 3.4Å; A173-S177 PolarHBondContact O-OG 2.83Å; I174-S177 PolarHBondContact O-N 3.3Å; I175-S177 VanDerWaalsContact C-N 3.32Å; I175-S177 PolarHBondContact O-N 2.78Å; S177-T180 WeakPolarHBondContact O-CB 3.37Å; S177-T180 PolarHBondContact O-N 2.92Å; S177-I181 WeakPolarHBondContact O-CG1 3.34Å; S177-I181 PolarHBondContact O-N 3.03Å
178	S	95.3	Very high	95.1	Very high	10 Å²	10	15.7 Å²	15.7	7%	0.07	9%	0.093	C	C	.	.	H	α-helix	trans	-65.4	-47.7	179.7	-59	0	0	0	0	111.3	S138 V141 S142 I174 I175 T180 I181 F182	S138-S178 VanDerWaalsContact CB-O 3.24Å; S138-S178 WeakPolarHBondContact CB-O 3.42Å; V141-S178 WeakPolarHBondContact CG1-OG 3.33Å; S142-S178 VanDerWaalsContact OG-CB 3.27Å; S142-S178 WeakPolarHBondContact OG-CB 3.28Å; I174-S178 VanDerWaalsContact O-CB 3.29Å; I174-S178 WeakPolarHBondContact O-CB 3.39Å; I174-S178 PolarHBondContact O-N 2.94Å; I174-S178 PolarHBondContact O-OG 2.97Å; I175-S178 PolarHBondContact O-N 2.98Å; S178-T180 PolarHBondContact O-N 3.35Å; S178-I181 PolarHBondContact O-N 3.33Å; S178-F182 WeakPolarHBondContact O-CB 3.49Å; S178-F182 PolarHBondContact O-N 2.68Å
179	S	94.9	Very high	95.1	Very high	9 Å²	9	15.9 Å²	15.9	6%	0.063	9%	0.094	C	C	.	.	H	α-helix	trans	-57.5	-34.5	172.8	-64.3	0	0	0	0	111.7	I175 N183	I175-S179 WeakPolarHBondContact O-CB 3.41Å; I175-S179 PolarHBondContact O-N 2.75Å; I175-S179 PolarHBondContact O-OG 3.26Å; I175-S179 VanDerWaalsContact O-OG 3.09Å; S179-N183 VanDerWaalsContact O-CB 3.32Å; S179-N183 WeakPolarHBondContact O-CB 3.3Å; S179-N183 PolarHBondContact O-N 3.32Å; S179-N183 PolarHBondContact O-ND2 3.26Å
180	T	95.5	Very high	95.1	Very high	21 Å²	21	14.3 Å²	14.3	13%	0.129	9%	0.086	C	C	.	.	H	α-helix	trans	-70.4	-43.6	176.8	-55.3	0	0	0	0	112.1	S115 L119 S176 S177 S178 F182 S184	S115-T180 VanDerWaalsContact CB-OG1 3.23Å; S115-T180 WeakPolarHBondContact CB-OG1 3.41Å; S115-T180 WeakPolarHBondContact O-CG2 3.38Å; S115-T180 PolarHBondContact OG-OG1 2.93Å; L119-T180 HydrophobicContact CB-CG2 3.81Å; L119-T180 HydrophobicContact CD1-CG2 4.23Å; S176-T180 WeakPolarHBondContact O-CB 3.27Å; S176-T180 PolarHBondContact O-N 3.37Å; S176-T180 PolarHBondContact O-OG1 3.14Å; S177-T180 WeakPolarHBondContact O-CB 3.37Å; S177-T180 PolarHBondContact O-N 2.92Å; S178-T180 PolarHBondContact O-N 3.35Å; T180-F182 VanDerWaalsContact C-N 3.32Å; T180-F182 PolarHBondContact O-N 3.08Å; T180-S184 WeakPolarHBondContact O-CB 3.32Å; T180-S184 PolarHBondContact O-N 3.49Å; T180-S184 PolarHBondContact O-OG 3.37Å
181	I	95.8	Very high	94.9	Very high	35 Å²	35	12.2 Å²	12.2	18%	0.179	7%	0.069	C	C	.	.	H	α-helix	trans	-61.2	-44.3	173.6	-65.2	166.9	0	0	0	110.4	F118 R134 S177 S178 S184 S185	F118-I181 HydrophobicContact CB-CG1 4.4Å; F118-I181 HydrophobicContact CD1-CD1 3.44Å; F118-I181 VanDerWaalsContact CD1-CD1 3.44Å; F118-I181 HydrophobicContact CD1-CG1 3.93Å; F118-I181 HydrophobicContact CE1-CD1 3.92Å; R134-I181 HydrophobicContact CB-CG2 4.09Å; S177-I181 WeakPolarHBondContact O-CG1 3.34Å; S177-I181 PolarHBondContact O-N 3.03Å; S178-I181 PolarHBondContact O-N 3.33Å; I181-S184 PolarHBondContact O-OG 3.3Å; I181-S185 WeakPolarHBondContact O-CB 3.23Å; I181-S185 PolarHBondContact O-N 2.89Å; I181-S185 PolarHBondContact O-OG 3.12Å
182	F	96.3	Very high	94.6	Very high	3 Å²	3	13.1 Å²	13.1	1%	0.013	8%	0.075	C	C	.	.	H	α-helix	trans	-58	-61.1	177	171	-108.4	0	0	0	111	L60 G64 V135 S138 L139 S178 T180 S184 S185 V186	L60-F182 HydrophobicContact CB-CZ 4.26Å; L60-F182 HydrophobicContact CD2-CE2 4.31Å; L60-F182 HydrophobicContact CD2-CZ 4.02Å; G64-F182 VanDerWaalsContact CA-CE1 3.47Å; V135-F182 HydrophobicContact CG1-CD2 3.94Å; V135-F182 HydrophobicContact CG1-CE2 3.91Å; S138-F182 WeakPolarHBondContact OG-CA 3.5Å; S138-F182 WeakPolarHBondContact OG-CB 3.46Å; L139-F182 HydrophobicContact CD1-CD2 4.08Å; L139-F182 HydrophobicContact CD1-CE2 3.78Å; L139-F182 HydrophobicContact CD2-CD2 3.72Å; L139-F182 HydrophobicContact CD2-CE2 3.73Å; L139-F182 HydrophobicContact CD2-CG 4.13Å; L139-F182 HydrophobicContact CD2-CZ 4.14Å; L139-F182 HydrophobicContact CG-CD2 3.66Å; L139-F182 HydrophobicContact CG-CE2 3.82Å; L139-F182 HydrophobicContact CG-CG 4.42Å; S178-F182 WeakPolarHBondContact O-CB 3.49Å; S178-F182 PolarHBondContact O-N 2.68Å; T180-F182 VanDerWaalsContact C-N 3.32Å; T180-F182 PolarHBondContact O-N 3.08Å; F182-S184 VanDerWaalsContact C-N 3.35Å; F182-S184 PolarHBondContact O-N 2.88Å; F182-S185 PolarHBondContact O-N 3.05Å; F182-V186 HydrophobicContact CD2-CG2 3.97Å; F182-V186 HydrophobicContact CE2-CG2 3.58Å; F182-V186 HydrophobicContact CZ-CG2 4Å; F182-V186 WeakPolarHBondContact O-CG2 3.47Å; F182-V186 PolarHBondContact O-N 3.32Å
183	N	95	Very high	94.5	Very high	28 Å²	28	13.1 Å²	13.1	15%	0.15	8%	0.075	C	C	.	.	H	α-helix	trans	-58.2	-48.3	-177.5	-79.5	-67.8	0	0	0	110.8	G64 S179 S185 V186 Y187	G64-N183 WeakPolarHBondContact CA-OD1 3.41Å; G64-N183 PolarHBondContact O-ND2 3.07Å; S179-N183 VanDerWaalsContact O-CB 3.32Å; S179-N183 WeakPolarHBondContact O-CB 3.3Å; S179-N183 PolarHBondContact O-N 3.32Å; S179-N183 PolarHBondContact O-ND2 3.26Å; N183-S185 VanDerWaalsContact C-N 3.33Å; N183-S185 PolarHBondContact O-N 3.08Å; N183-V186 PolarHBondContact O-N 3.06Å; N183-Y187 WeakPolarHBondContact O-CB 3.09Å; N183-Y187 WeakPolarHBondContact O-CD2 3.5Å; N183-Y187 PolarHBondContact O-N 3.34Å
184	S	95.6	Very high	94.3	Very high	1 Å²	1	12.2 Å²	12.2	1%	0.007	7%	0.068	C	C	.	.	H	α-helix	trans	-66.6	-33	-178.6	63.1	0	0	0	0	113.7	N122 T180 I181 F182 G188 L454	N122-S184 PolarHBondContact ND2-OG 2.9Å; T180-S184 WeakPolarHBondContact O-CB 3.32Å; T180-S184 PolarHBondContact O-N 3.49Å; T180-S184 PolarHBondContact O-OG 3.37Å; I181-S184 PolarHBondContact O-OG 3.3Å; F182-S184 VanDerWaalsContact C-N 3.35Å; F182-S184 PolarHBondContact O-N 2.88Å; S184-G188 PolarHBondContact O-N 3.32Å; S184-L454 VanDerWaalsContact CA-CD1 3.49Å
185	S	96.2	Very high	94.1	Very high	0 Å²	0	10.6 Å²	10.6	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-71.1	-42.5	174.7	-66.8	0	0	0	0	112.5	N122 R134 I181 F182 N183 G188 L189	N122-S185 PolarHBondContact OD1-OG 3.35Å; R134-S185 WeakPolarHBondContact CB-OG 3.37Å; R134-S185 PolarHBondContact NE-OG 3.04Å; I181-S185 WeakPolarHBondContact O-CB 3.23Å; I181-S185 PolarHBondContact O-N 2.89Å; I181-S185 PolarHBondContact O-OG 3.12Å; F182-S185 PolarHBondContact O-N 3.05Å; N183-S185 VanDerWaalsContact C-N 3.33Å; N183-S185 PolarHBondContact O-N 3.08Å; S185-G188 PolarHBondContact O-N 2.85Å; S185-L189 WeakPolarHBondContact O-CB 3.27Å; S185-L189 PolarHBondContact O-N 3.35Å
186	V	96.1	Very high	94	Very high	1 Å²	1	14.2 Å²	14.2	1%	0.006	7%	0.072	C	C	.	.	H	α-helix	trans	-71	-38.5	178.1	-176.6	0	0	0	0	111	F57 L60 V135 F182 N183 L189 T190 L201	F57-V186 HydrophobicContact CD1-CG1 4.08Å; F57-V186 HydrophobicContact CE1-CG1 4.1Å; L60-V186 HydrophobicContact CB-CG1 4.32Å; L60-V186 HydrophobicContact CD1-CG1 3.98Å; V135-V186 HydrophobicContact CG1-CG2 4.25Å; V135-V186 HydrophobicContact CG2-CG2 3.77Å; F182-V186 HydrophobicContact CD2-CG2 3.97Å; F182-V186 HydrophobicContact CE2-CG2 3.58Å; F182-V186 HydrophobicContact CZ-CG2 4Å; F182-V186 WeakPolarHBondContact O-CG2 3.47Å; F182-V186 PolarHBondContact O-N 3.32Å; N183-V186 PolarHBondContact O-N 3.06Å; V186-L189 WeakPolarHBondContact O-CB 3.14Å; V186-L189 PolarHBondContact O-N 2.81Å; V186-T190 WeakPolarHBondContact O-CG2 3.47Å; V186-T190 PolarHBondContact O-N 3.48Å; V186-L201 HydrophobicContact CB-CD1 4.47Å; V186-L201 HydrophobicContact CB-CD2 4.37Å; V186-L201 HydrophobicContact CG1-CD1 3.59Å; V186-L201 HydrophobicContact CG1-CD2 3.82Å; V186-L201 HydrophobicContact CG1-CG 4.37Å
187	Y	95	Very high	94	Very high	30 Å²	30	14.3 Å²	14.3	12%	0.118	7%	0.073	C	C	.	.	H	α-helix	trans	-60.9	-47.3	169.7	-96.9	-91.4	0	0	0	111.6	N183 L189 T190 G191 L201 I202 L434 S450 L454	N183-Y187 WeakPolarHBondContact O-CB 3.09Å; N183-Y187 WeakPolarHBondContact O-CD2 3.5Å; N183-Y187 PolarHBondContact O-N 3.34Å; Y187-L189 VanDerWaalsContact C-N 3.27Å; Y187-L189 PolarHBondContact O-N 3.26Å; Y187-T190 PolarHBondContact O-N 3.31Å; Y187-T190 VanDerWaalsContact O-N 3.08Å; Y187-T190 PolarHBondContact O-OG1 3.29Å; Y187-G191 PolarHBondContact O-N 3.06Å; Y187-L201 HydrophobicContact CD1-CD2 4.21Å; Y187-L201 HydrophobicContact CD2-CD2 3.57Å; Y187-L201 HydrophobicContact CD2-CG 4.32Å; Y187-L201 HydrophobicContact CE2-CD2 3.93Å; Y187-L201 HydrophobicContact CE2-CG 4.21Å; Y187-L201 HydrophobicContact CG-CD2 3.74Å; Y187-I202 HydrophobicContact CD1-CG1 4.49Å; Y187-I202 HydrophobicContact CE1-CD1 3.98Å; Y187-I202 HydrophobicContact CE1-CG1 3.35Å; Y187-I202 WeakPolarHBondContact OH-CG1 3.29Å; Y187-L434 HydrophobicContact CE1-CD1 4.18Å; Y187-S450 WeakPolarHBondContact O-CB 3.27Å; Y187-L454 HydrophobicContact CD1-CD1 4.42Å; Y187-L454 HydrophobicContact CD1-CD2 4.12Å; Y187-L454 HydrophobicContact CD1-CG 4.36Å; Y187-L454 HydrophobicContact CD2-CD1 3.94Å; Y187-L454 HydrophobicContact CD2-CD2 4.15Å; Y187-L454 HydrophobicContact CE1-CD2 4.13Å; Y187-L454 HydrophobicContact CE2-CD2 4.18Å; Y187-L454 HydrophobicContact CG-CD1 3.75Å; Y187-L454 HydrophobicContact CG-CD2 4.1Å; Y187-L454 HydrophobicContact CG-CG 4.18Å
188	G	94.3	Very high	94	Very high	0 Å²	0	14.1 Å²	14.1	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-46.2	-53.5	170.2	0	0	0	0	0	111.9	S184 S185 T190 G191 E447	S184-G188 PolarHBondContact O-N 3.32Å; S185-G188 PolarHBondContact O-N 2.85Å; G188-T190 VanDerWaalsContact C-N 3.31Å; G188-T190 PolarHBondContact O-N 2.95Å; G188-G191 PolarHBondContact O-N 2.96Å; G188-E447 VanDerWaalsContact O-CA 3.29Å; G188-E447 WeakPolarHBondContact O-CA 3.29Å
189	L	93.7	Very high	94.1	Very high	5 Å²	5	13.7 Å²	13.7	3%	0.026	7%	0.069	C	C	.	.	H	α-helix	trans	-55.3	-45.4	178.9	-174.9	58.7	0	0	0	112.2	F57 V131 S185 V186 Y187 G191 S192 F193 Y248 L251 M261	F57-L189 HydrophobicContact CE1-CD2 4.31Å; F57-L189 HydrophobicContact CZ-CD2 4.33Å; F57-L189 HydrophobicContact CZ-CG 4.47Å; V131-L189 HydrophobicContact CG1-CD1 4.25Å; V131-L189 HydrophobicContact CG2-CB 4.24Å; S185-L189 WeakPolarHBondContact O-CB 3.27Å; S185-L189 PolarHBondContact O-N 3.35Å; V186-L189 WeakPolarHBondContact O-CB 3.14Å; V186-L189 PolarHBondContact O-N 2.81Å; Y187-L189 VanDerWaalsContact C-N 3.27Å; Y187-L189 PolarHBondContact O-N 3.26Å; L189-G191 PolarHBondContact O-N 3.38Å; L189-G191 VanDerWaalsContact O-N 3.14Å; L189-S192 PolarHBondContact O-N 3.3Å; L189-S192 VanDerWaalsContact O-N 3.17Å; L189-F193 HydrophobicContact CD1-CE2 3.93Å; L189-F193 HydrophobicContact CG-CD2 4.42Å; L189-F193 HydrophobicContact CG-CE2 3.9Å; L189-F193 VanDerWaalsContact O-CD2 3.29Å; L189-F193 WeakPolarHBondContact O-CD2 3.45Å; L189-Y248 HydrophobicContact CD2-CE2 4.12Å; L189-L251 HydrophobicContact CD2-CD2 4.21Å; L189-M261 HydrophobicContact CD1-CG 3.72Å; L189-M261 HydrophobicContact CD1-SD 3.76Å; L189-M261 HydrophobicContact CD2-SD 4.26Å
190	T	94.1	Very high	94.2	Very high	3 Å²	3	13.2 Å²	13.2	2%	0.018	7%	0.066	C	C	.	.	H	α-helix	trans	-63.3	-19.2	-179.9	64.2	0	0	0	0	114	F57 V186 Y187 G188 S192 F193 L201	F57-T190 HydrophobicContact CD1-CG2 3.55Å; F57-T190 HydrophobicContact CE1-CG2 3.39Å; F57-T190 HydrophobicContact CG-CG2 4.27Å; F57-T190 HydrophobicContact CZ-CG2 3.98Å; V186-T190 WeakPolarHBondContact O-CG2 3.47Å; V186-T190 PolarHBondContact O-N 3.48Å; Y187-T190 PolarHBondContact O-N 3.31Å; Y187-T190 VanDerWaalsContact O-N 3.08Å; Y187-T190 PolarHBondContact O-OG1 3.29Å; G188-T190 VanDerWaalsContact C-N 3.31Å; G188-T190 PolarHBondContact O-N 2.95Å; T190-S192 PolarHBondContact O-N 3.16Å; T190-F193 PolarHBondContact O-N 3.49Å; T190-L201 HydrophobicContact CG2-CB 4.22Å; T190-L201 HydrophobicContact CG2-CD2 3.75Å
191	G	90.9	Very high	94.2	Very high	1 Å²	1	12.3 Å²	12.3	1%	0.01	6%	0.06	C	C	.	.	T	Hydrogen-bonded Turn	trans	-56.4	-33.9	174	0	0	0	0	0	113.1	Y187 G188 L189 K439 A446 S450	Y187-G191 PolarHBondContact O-N 3.06Å; G188-G191 PolarHBondContact O-N 2.96Å; L189-G191 PolarHBondContact O-N 3.38Å; L189-G191 VanDerWaalsContact O-N 3.14Å; G191-K439 PolarHBondContact O-NZ 2.87Å; G191-A446 WeakPolarHBondContact O-CB 3.37Å; G191-S450 WeakPolarHBondContact CA-OG 3.37Å
192	S	87.9	Confident	94.3	Very high	24 Å²	24	10.8 Å²	10.8	17%	0.168	5%	0.052	C	C	.	.	T	Hydrogen-bonded Turn	trans	-83.2	-16.7	177.1	-63.7	0	0	0	0	113.8	L189 T190 Y260	L189-S192 PolarHBondContact O-N 3.3Å; L189-S192 VanDerWaalsContact O-N 3.17Å; T190-S192 PolarHBondContact O-N 3.16Å; S192-Y260 WeakPolarHBondContact O-CD1 3.33Å
193	F	92.1	Very high	94.3	Very high	1 Å²	1	10.6 Å²	10.6	0%	0.004	5%	0.051	C	C	.	.	S	Bend	trans	-92	166.5	-178.6	-78.5	-108.6	0	0	0	111.5	F57 L189 T190 N197 Y256 A257 Y260 M261 K439	F57-F193 AromaticContact CE2-CD1 3.78Å; F57-F193 HydrophobicContact CE2-CD1 3.78Å; F57-F193 AromaticContact CE2-CE1 3.81Å; F57-F193 HydrophobicContact CE2-CE1 3.81Å; F57-F193 HydrophobicContact CE2-CG 4.19Å; F57-F193 HydrophobicContact CE2-CZ 4.27Å; F57-F193 HydrophobicContact CZ-CD1 4.17Å; F57-F193 HydrophobicContact CZ-CD2 4.22Å; F57-F193 HydrophobicContact CZ-CE1 4.1Å; F57-F193 HydrophobicContact CZ-CE2 4.16Å; F57-F193 HydrophobicContact CZ-CG 4.22Å; F57-F193 HydrophobicContact CZ-CZ 4.09Å; L189-F193 HydrophobicContact CD1-CE2 3.93Å; L189-F193 HydrophobicContact CG-CD2 4.42Å; L189-F193 HydrophobicContact CG-CE2 3.9Å; L189-F193 VanDerWaalsContact O-CD2 3.29Å; L189-F193 WeakPolarHBondContact O-CD2 3.45Å; T190-F193 PolarHBondContact O-N 3.49Å; F193-N197 HydrophobicContact CB-CB 3.88Å; F193-N197 HydrophobicContact CD1-CB 4.41Å; F193-N197 HydrophobicContact CG-CB 4.48Å; F193-Y256 AromaticContact CD1-CE1 3.96Å; F193-Y256 HydrophobicContact CD1-CE1 3.96Å; F193-Y256 HydrophobicContact CE1-CD1 4.23Å; F193-Y256 HydrophobicContact CE1-CE1 4.13Å; F193-A257 HydrophobicContact CE1-CB 4.03Å; F193-A257 HydrophobicContact CZ-CB 3.94Å; F193-Y260 AromaticContact CD1-CD2 3.77Å; F193-Y260 HydrophobicContact CD1-CD2 3.77Å; F193-Y260 HydrophobicContact CD1-CG 4.04Å; F193-Y260 AromaticContact CE1-CD2 3.88Å; F193-Y260 HydrophobicContact CE1-CD2 3.88Å; F193-Y260 HydrophobicContact CE1-CG 4.29Å; F193-Y260 HydrophobicContact CG-CD2 4.37Å; F193-Y260 HydrophobicContact CG-CG 4.2Å; F193-M261 HydrophobicContact CE2-CG 3.92Å; F193-M261 HydrophobicContact CZ-CG 4.04Å; F193-K439 WeakPolarHBondContact O-CE 3.47Å; F193-K439 PolarHBondContact O-NZ 3.39Å
194	P	91.4	Very high	94.3	Very high	5 Å²	5	9.3 Å²	9.3	3%	0.032	4%	0.044	C	C	.	.			trans	-47.9	148.2	166.7	-38.1	48.3	0	0	0	114.1	Y10 R196 N197 A198 Y256 Y260	Y10-P194 WeakPolarHBondContact OH-CB 3.29Å; Y10-P194 WeakPolarHBondContact OH-CG 3.46Å; P194-R196 PolarHBondContact O-N 3.33Å; P194-R196 VanDerWaalsContact O-N 3.08Å; P194-N197 WeakPolarHBondContact CB-OD1 3.5Å; P194-N197 WeakPolarHBondContact CD-OD1 3.27Å; P194-N197 PolarHBondContact O-N 3.34Å; P194-A198 PolarHBondContact O-N 3.34Å; P194-Y256 VanDerWaalsContact CG-OH 3.3Å; P194-Y256 WeakPolarHBondContact CG-OH 3.14Å; P194-Y260 HydrophobicContact CG-CE1 4.08Å; P194-Y260 HydrophobicContact CG-CE2 4.46Å
195	M	91.9	Very high	94.3	Very high	38 Å²	38	9.6 Å²	9.6	19%	0.187	5%	0.048	C	C	.	.	H	α-helix	trans	-56.3	-29.2	176.8	-67	172.1	68	0	0	112.3	N197 A198 Q199 Q370 I435 Y436 K439	M195-N197 VanDerWaalsContact C-N 3.32Å; M195-N197 PolarHBondContact O-N 2.93Å; M195-A198 PolarHBondContact O-N 3.03Å; M195-Q199 VanDerWaalsContact O-CB 3.32Å; M195-Q199 WeakPolarHBondContact O-CB 3.27Å; M195-Q199 PolarHBondContact O-N 3.35Å; M195-Q370 VanDerWaalsContact CE-OE1 3.24Å; M195-I435 HydrophobicContact CB-CB 4.48Å; M195-I435 HydrophobicContact CE-CB 4.08Å; M195-I435 HydrophobicContact CE-CD1 3.58Å; M195-I435 HydrophobicContact CE-CG1 3.53Å; M195-Y436 HydrophobicContact CE-CD1 3.44Å; M195-Y436 VanDerWaalsContact CE-CD1 3.44Å; M195-Y436 HydrophobicContact CE-CE1 3.54Å; M195-K439 HydrophobicContact CG-CD 4.13Å; M195-K439 HydrophobicContact CG-CG 3.72Å; M195-K439 HydrophobicContact SD-CG 4.03Å
196	R	92.9	Very high	94.2	Very high	76 Å²	76	9.9 Å²	9.9	29%	0.287	5%	0.05	S	C	.	.	H	α-helix	trans	-60.2	-37.7	175.3	-169.1	-176.5	170.3	-158.5	-5.1	112.6	E6 N51 Y54 P194 A200	E6-R196 IonicContact OE1-NH1 3.95Å; N51-R196 PolarHBondContact OD1-NH1 2.96Å; N51-R196 PolarHBondContact OD1-NH2 3.45Å; Y54-R196 HydrophobicContact CD2-CG 3.77Å; Y54-R196 HydrophobicContact CE2-CG 3.81Å; P194-R196 PolarHBondContact O-N 3.33Å; P194-R196 VanDerWaalsContact O-N 3.08Å; R196-A200 WeakPolarHBondContact O-CB 3.11Å; R196-A200 PolarHBondContact O-N 3.34Å
197	N	94.6	Very high	94.2	Very high	3 Å²	3	12.4 Å²	12.4	2%	0.016	6%	0.062	C	C	.	.	H	α-helix	trans	-73.1	-40.3	177.7	-62	83	0	0	0	111.7	F57 F193 P194 M195 Q199 A200 L201 Y256	F57-N197 HydrophobicContact CD2-CB 3.67Å; F57-N197 HydrophobicContact CE2-CB 3.88Å; F57-N197 HydrophobicContact CG-CB 4.37Å; F193-N197 HydrophobicContact CB-CB 3.88Å; F193-N197 HydrophobicContact CD1-CB 4.41Å; F193-N197 HydrophobicContact CG-CB 4.48Å; P194-N197 WeakPolarHBondContact CB-OD1 3.5Å; P194-N197 WeakPolarHBondContact CD-OD1 3.27Å; P194-N197 PolarHBondContact O-N 3.34Å; M195-N197 VanDerWaalsContact C-N 3.32Å; M195-N197 PolarHBondContact O-N 2.93Å; N197-Q199 VanDerWaalsContact C-N 3.33Å; N197-A200 WeakPolarHBondContact O-CB 3.4Å; N197-A200 PolarHBondContact O-N 3.11Å; N197-L201 PolarHBondContact O-N 3.33Å; N197-Y256 PolarHBondContact OD1-OH 3.16Å
198	A	95	Very high	94.1	Very high	3 Å²	3	11 Å²	11	3%	0.025	6%	0.057	C	C	.	.	H	α-helix	trans	-60.6	-45	172.1	0	0	0	0	0	110.8	P194 M195 A200 L201 I202 I435	P194-A198 PolarHBondContact O-N 3.34Å; M195-A198 PolarHBondContact O-N 3.03Å; A198-A200 VanDerWaalsContact C-N 3.33Å; A198-A200 PolarHBondContact O-N 2.73Å; A198-L201 WeakPolarHBondContact O-CB 3.29Å; A198-L201 PolarHBondContact O-N 3.42Å; A198-I202 WeakPolarHBondContact O-CB 3.45Å; A198-I202 VanDerWaalsContact O-CD1 3.29Å; A198-I202 WeakPolarHBondContact O-CD1 3.33Å; A198-I202 WeakPolarHBondContact O-CG1 3.45Å; A198-I202 PolarHBondContact O-N 2.56Å; A198-I435 HydrophobicContact CB-CG2 3.83Å
199	Q	96.1	Very high	94	Very high	0 Å²	0	11.2 Å²	11.2	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-59.1	-42.9	174.6	-177.3	-79.4	-35.5	0	0	111.8	Y54 M195 N197 L201 I202 S203 R363 T366 T431 I435	Y54-Q199 PolarHBondContact OH-OE1 3.1Å; M195-Q199 VanDerWaalsContact O-CB 3.32Å; M195-Q199 WeakPolarHBondContact O-CB 3.27Å; M195-Q199 PolarHBondContact O-N 3.35Å; N197-Q199 VanDerWaalsContact C-N 3.33Å; Q199-L201 PolarHBondContact O-N 3.39Å; Q199-I202 PolarHBondContact O-N 3.09Å; Q199-S203 VanDerWaalsContact O-CB 3.26Å; Q199-S203 WeakPolarHBondContact O-CB 3.31Å; Q199-S203 PolarHBondContact O-N 3.42Å; Q199-R363 PolarHBondContact NE2-O 2.95Å; Q199-T366 WeakPolarHBondContact CG-OG1 3.06Å; Q199-T431 HydrophobicContact CB-CG2 4.39Å; Q199-T431 HydrophobicContact CG-CG2 3.99Å; Q199-I435 HydrophobicContact CB-CG2 4.32Å
200	A	96.9	Very high	94.1	Very high	0 Å²	0	11.6 Å²	11.6	0%	0	6%	0.062	C	C	.	.	H	α-helix	trans	-58.7	-48.5	176.9	0	0	0	0	0	111.5	Y54 F57 F58 R196 N197 A198 I202 S203 G204	Y54-A200 HydrophobicContact CD1-CB 4.31Å; Y54-A200 HydrophobicContact CD2-CB 3.53Å; Y54-A200 HydrophobicContact CE1-CB 4.23Å; Y54-A200 HydrophobicContact CE2-CB 3.46Å; Y54-A200 VanDerWaalsContact CE2-CB 3.46Å; Y54-A200 HydrophobicContact CG-CB 3.97Å; F57-A200 HydrophobicContact CB-CB 4.13Å; F58-A200 WeakPolarHBondContact CA-O 3.4Å; F58-A200 HydrophobicContact CB-CB 4.33Å; F58-A200 WeakPolarHBondContact CD2-O 3.31Å; R196-A200 WeakPolarHBondContact O-CB 3.11Å; R196-A200 PolarHBondContact O-N 3.34Å; N197-A200 WeakPolarHBondContact O-CB 3.4Å; N197-A200 PolarHBondContact O-N 3.11Å; A198-A200 VanDerWaalsContact C-N 3.33Å; A198-A200 PolarHBondContact O-N 2.73Å; A200-I202 PolarHBondContact O-N 3.07Å; A200-S203 PolarHBondContact O-N 2.8Å; A200-G204 PolarHBondContact O-N 3.41Å
201	L	97.2	Very high	94	Very high	2 Å²	2	14 Å²	14	1%	0.01	8%	0.076	C	C	.	.	H	α-helix	trans	-58.1	-48.4	176.3	-179.3	71	0	0	0	111.8	F57 L60 G61 V186 Y187 T190 N197 A198 Q199 G204 G205	F57-L201 HydrophobicContact CB-CB 4.27Å; F57-L201 HydrophobicContact CD1-CB 4.47Å; F57-L201 WeakPolarHBondContact O-CA 3.33Å; F57-L201 WeakPolarHBondContact O-CD1 3.17Å; L60-L201 HydrophobicContact CB-CD1 4.05Å; G61-L201 WeakPolarHBondContact CA-O 3.15Å; V186-L201 HydrophobicContact CB-CD1 4.47Å; V186-L201 HydrophobicContact CB-CD2 4.37Å; V186-L201 HydrophobicContact CG1-CD1 3.59Å; V186-L201 HydrophobicContact CG1-CD2 3.82Å; V186-L201 HydrophobicContact CG1-CG 4.37Å; Y187-L201 HydrophobicContact CD1-CD2 4.21Å; Y187-L201 HydrophobicContact CD2-CD2 3.57Å; Y187-L201 HydrophobicContact CD2-CG 4.32Å; Y187-L201 HydrophobicContact CE2-CD2 3.93Å; Y187-L201 HydrophobicContact CE2-CG 4.21Å; Y187-L201 HydrophobicContact CG-CD2 3.74Å; T190-L201 HydrophobicContact CG2-CB 4.22Å; T190-L201 HydrophobicContact CG2-CD2 3.75Å; N197-L201 PolarHBondContact O-N 3.33Å; A198-L201 WeakPolarHBondContact O-CB 3.29Å; A198-L201 PolarHBondContact O-N 3.42Å; Q199-L201 PolarHBondContact O-N 3.39Å; L201-G204 PolarHBondContact O-N 3.5Å; L201-G205 PolarHBondContact O-N 2.9Å; L201-G205 VanDerWaalsContact O-N 3.16Å
202	I	96.1	Very high	94.1	Very high	2 Å²	2	14.2 Å²	14.2	1%	0.01	8%	0.077	C	C	.	.	H	α-helix	trans	-61.8	-45	179.6	-67.9	159	0	0	0	111	Y187 A198 Q199 A200 G205 R363 T431 L434 I435	Y187-I202 HydrophobicContact CD1-CG1 4.49Å; Y187-I202 HydrophobicContact CE1-CD1 3.98Å; Y187-I202 HydrophobicContact CE1-CG1 3.35Å; Y187-I202 WeakPolarHBondContact OH-CG1 3.29Å; A198-I202 WeakPolarHBondContact O-CB 3.45Å; A198-I202 VanDerWaalsContact O-CD1 3.29Å; A198-I202 WeakPolarHBondContact O-CD1 3.33Å; A198-I202 WeakPolarHBondContact O-CG1 3.45Å; A198-I202 PolarHBondContact O-N 2.56Å; Q199-I202 PolarHBondContact O-N 3.09Å; A200-I202 PolarHBondContact O-N 3.07Å; I202-G205 PolarHBondContact O-N 3.26Å; I202-R363 HydrophobicContact CG2-CG 4.48Å; I202-R363 WeakPolarHBondContact O-CD 3.38Å; I202-T431 HydrophobicContact CB-CG2 4.21Å; I202-T431 HydrophobicContact CD1-CG2 4.01Å; I202-T431 HydrophobicContact CG2-CG2 3.82Å; I202-T431 VanDerWaalsContact CG2-OG1 3.28Å; I202-T431 WeakPolarHBondContact CG2-OG1 3.49Å; I202-L434 HydrophobicContact CD1-CB 3.76Å; I202-L434 HydrophobicContact CD1-CD1 4.38Å; I202-L434 HydrophobicContact CG1-CD1 4.38Å; I202-I435 HydrophobicContact CD1-CG2 3.46Å; I202-I435 VanDerWaalsContact CD1-CG2 3.46Å
203	S	96.9	Very high	94.3	Very high	0 Å²	0	13.3 Å²	13.3	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-64.6	-40.1	177.6	-165.7	0	0	0	0	111.8	Q199 A200 G205 A206 M207 L360 Q364	Q199-S203 VanDerWaalsContact O-CB 3.26Å; Q199-S203 WeakPolarHBondContact O-CB 3.31Å; Q199-S203 PolarHBondContact O-N 3.42Å; A200-S203 PolarHBondContact O-N 2.8Å; S203-G205 VanDerWaalsContact C-N 3.25Å; S203-G205 PolarHBondContact O-N 3.33Å; S203-A206 PolarHBondContact O-N 3.36Å; S203-A206 VanDerWaalsContact O-N 3.12Å; S203-M207 PolarHBondContact O-N 2.95Å; S203-L360 WeakPolarHBondContact O-CD1 3.31Å; S203-Q364 PolarHBondContact OG-OE1 3.42Å; S203-Q364 VanDerWaalsContact OG-OE1 3.05Å
204	G	96.3	Very high	94.4	Very high	0 Å²	0	16.6 Å²	16.6	0%	0	9%	0.091	C	C	.	.	H	α-helix	trans	-56.5	-39	173.6	0	0	0	0	0	112.8	F58 G61 I62 A200 L201 A206 M207 G208	F58-G204 VanDerWaalsContact O-CA 3.26Å; F58-G204 WeakPolarHBondContact O-CA 3.46Å; G61-G204 CarbonylContact C-O 3.55Å; I62-G204 VanDerWaalsContact CA-O 3.28Å; I62-G204 WeakPolarHBondContact CA-O 3.33Å; I62-G204 WeakPolarHBondContact CG1-O 3.46Å; I62-G204 PolarHBondContact N-O 3.5Å; A200-G204 PolarHBondContact O-N 3.41Å; L201-G204 PolarHBondContact O-N 3.5Å; G204-A206 PolarHBondContact O-N 3.16Å; G204-M207 WeakPolarHBondContact O-CB 3.26Å; G204-M207 PolarHBondContact O-N 3.38Å; G204-G208 PolarHBondContact O-N 2.98Å
205	G	94.8	Very high	94.3	Very high	8 Å²	8	17.1 Å²	17.1	8%	0.082	10%	0.097	C	C	.	.	H	α-helix	trans	-57.2	-46.9	173.6	0	0	0	0	0	113.3	G61 L65 L201 I202 S203 M207 G208 G209	G61-G205 WeakPolarHBondContact O-CA 3.37Å; L65-G205 WeakPolarHBondContact CD1-O 3.27Å; L201-G205 PolarHBondContact O-N 2.9Å; L201-G205 VanDerWaalsContact O-N 3.16Å; I202-G205 PolarHBondContact O-N 3.26Å; S203-G205 VanDerWaalsContact C-N 3.25Å; S203-G205 PolarHBondContact O-N 3.33Å; G205-M207 VanDerWaalsContact C-N 3.33Å; G205-M207 PolarHBondContact O-N 3.45Å; G205-G208 WeakPolarHBondContact O-CA 3.39Å; G205-G208 PolarHBondContact O-N 2.71Å; G205-G208 VanDerWaalsContact O-N 3.12Å; G205-G209 PolarHBondContact O-N 3.05Å; G205-G209 VanDerWaalsContact O-N 3.13Å
206	A	94.8	Very high	94.2	Very high	5 Å²	5	17.1 Å²	17.1	4%	0.041	10%	0.097	C	C	.	.	H	α-helix	trans	-68.3	-31.5	176.9	0	0	0	0	0	113.3	S203 G204 G208 G209 T210 D359 L360 R363	S203-A206 PolarHBondContact O-N 3.36Å; S203-A206 VanDerWaalsContact O-N 3.12Å; G204-A206 PolarHBondContact O-N 3.16Å; A206-G208 VanDerWaalsContact C-N 3.3Å; A206-G209 PolarHBondContact O-N 2.97Å; A206-T210 PolarHBondContact O-N 3.28Å; A206-T210 PolarHBondContact O-OG1 3.46Å; A206-D359 WeakPolarHBondContact CB-OD2 3.47Å; A206-L360 HydrophobicContact CB-CB 3.95Å; A206-L360 HydrophobicContact CB-CD1 4.19Å; A206-R363 HydrophobicContact CB-CG 4.47Å
207	M	95.2	Very high	94.2	Very high	55 Å²	55	14.6 Å²	14.6	27%	0.271	9%	0.089	S	C	.	.	H	α-helix	trans	-62.3	-41.1	170.2	178.7	62.9	76.6	0	0	110.5	F58 I62 S203 G204 G205 G209 T210 V211 L360	F58-M207 HydrophobicContact CE1-CB 4.32Å; F58-M207 HydrophobicContact CE1-CG 4.2Å; F58-M207 HydrophobicContact CZ-CB 3.79Å; F58-M207 HydrophobicContact CZ-CE 4.03Å; F58-M207 HydrophobicContact CZ-CG 4.04Å; I62-M207 HydrophobicContact CD1-CB 4.27Å; I62-M207 HydrophobicContact CD1-CG 3.75Å; I62-M207 HydrophobicContact CG1-CB 3.94Å; I62-M207 HydrophobicContact CG1-CG 3.92Å; S203-M207 PolarHBondContact O-N 2.95Å; G204-M207 WeakPolarHBondContact O-CB 3.26Å; G204-M207 PolarHBondContact O-N 3.38Å; G205-M207 VanDerWaalsContact C-N 3.33Å; G205-M207 PolarHBondContact O-N 3.45Å; M207-G209 VanDerWaalsContact C-N 3.32Å; M207-G209 PolarHBondContact O-N 2.84Å; M207-T210 PolarHBondContact O-N 3.17Å; M207-T210 VanDerWaalsContact O-N 3.15Å; M207-V211 HydrophobicContact CG-CG2 4.31Å; M207-V211 WeakPolarHBondContact O-CG2 3.39Å; M207-V211 PolarHBondContact O-N 3.42Å; M207-V211 HydrophobicContact SD-CG2 4.12Å; M207-L360 HydrophobicContact CB-CD1 4.15Å; M207-L360 HydrophobicContact CE-CD1 4.5Å; M207-L360 HydrophobicContact CE-CD2 3.57Å; M207-L360 HydrophobicContact SD-CD2 4.08Å
208	G	93	Very high	94	Very high	0 Å²	0	18.7 Å²	18.7	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-54.9	-46.1	171.4	0	0	0	0	0	112.5	L66 G204 G205 A206 V211 S212	L66-G208 WeakPolarHBondContact CD1-O 3.5Å; G204-G208 PolarHBondContact O-N 2.98Å; G205-G208 WeakPolarHBondContact O-CA 3.39Å; G205-G208 PolarHBondContact O-N 2.71Å; G205-G208 VanDerWaalsContact O-N 3.12Å; A206-G208 VanDerWaalsContact C-N 3.3Å; G208-V211 PolarHBondContact O-N 3.18Å; G208-S212 PolarHBondContact O-N 3.46Å; G208-S212 PolarHBondContact O-OG 3.28Å
209	G	92.6	Very high	93.7	Very high	5 Å²	5	19.6 Å²	19.6	5%	0.052	12%	0.118	C	C	.	.	H	α-helix	trans	-61.6	-41.6	173.8	0	0	0	0	0	113.9	G205 A206 M207 S212 A213 N356	G205-G209 PolarHBondContact O-N 3.05Å; G205-G209 VanDerWaalsContact O-N 3.13Å; A206-G209 PolarHBondContact O-N 2.97Å; M207-G209 VanDerWaalsContact C-N 3.32Å; M207-G209 PolarHBondContact O-N 2.84Å; G209-S212 PolarHBondContact O-N 2.96Å; G209-A213 PolarHBondContact O-N 2.99Å; G209-N356 VanDerWaalsContact CA-OD1 3.31Å; G209-N356 WeakPolarHBondContact CA-OD1 3.42Å
210	T	94.6	Very high	93.2	Very high	13 Å²	13	21 Å²	21	8%	0.08	13%	0.126	C	C	.	.	H	α-helix	trans	-65.3	-45.7	178	-55.7	0	0	0	0	111.3	A206 M207 S212 A213 V214 L353 N356 F357	A206-T210 PolarHBondContact O-N 3.28Å; A206-T210 PolarHBondContact O-OG1 3.46Å; M207-T210 PolarHBondContact O-N 3.17Å; M207-T210 VanDerWaalsContact O-N 3.15Å; T210-S212 VanDerWaalsContact C-N 3.31Å; T210-S212 PolarHBondContact O-N 3.2Å; T210-A213 PolarHBondContact O-N 3.08Å; T210-V214 WeakPolarHBondContact O-CG2 3.36Å; T210-V214 PolarHBondContact O-N 3.47Å; T210-L353 HydrophobicContact CG2-CD1 4.32Å; T210-N356 PolarHBondContact OG1-O 3.15Å; T210-F357 HydrophobicContact CG2-CD2 4.36Å
211	V	93.2	Very high	92.9	Very high	52 Å²	52	24.5 Å²	24.5	32%	0.315	16%	0.155	S	C	.	.	H	α-helix	trans	-60.6	-42.1	176.3	172.2	0	0	0	0	110.4	L66 F70 M207 G208 V214 A215	L66-V211 HydrophobicContact CD1-CB 3.89Å; L66-V211 HydrophobicContact CD1-CG1 3.73Å; F70-V211 HydrophobicContact CZ-CG1 4.42Å; M207-V211 HydrophobicContact CG-CG2 4.31Å; M207-V211 WeakPolarHBondContact O-CG2 3.39Å; M207-V211 PolarHBondContact O-N 3.42Å; M207-V211 HydrophobicContact SD-CG2 4.12Å; G208-V211 PolarHBondContact O-N 3.18Å; V211-V214 PolarHBondContact O-N 3.36Å; V211-A215 WeakPolarHBondContact O-CB 3.43Å; V211-A215 PolarHBondContact O-N 2.91Å
212	S	91.8	Very high	92.4	Very high	6 Å²	6	28.1 Å²	28.1	4%	0.042	18%	0.184	C	C	.	.	H	α-helix	trans	-62.7	-41.9	174.8	-59.7	0	0	0	0	113.2	L66 N69 G208 G209 T210 A215 L216	L66-S212 WeakPolarHBondContact CD1-OG 3.34Å; N69-S212 WeakPolarHBondContact CB-OG 3.37Å; N69-S212 PolarHBondContact ND2-OG 3.42Å; G208-S212 PolarHBondContact O-N 3.46Å; G208-S212 PolarHBondContact O-OG 3.28Å; G209-S212 PolarHBondContact O-N 2.96Å; T210-S212 VanDerWaalsContact C-N 3.31Å; T210-S212 PolarHBondContact O-N 3.2Å; S212-A215 PolarHBondContact O-N 2.93Å; S212-L216 WeakPolarHBondContact O-CB 3.33Å; S212-L216 PolarHBondContact O-N 3.19Å
213	A	93	Very high	91.7	Very high	6 Å²	6	30.3 Å²	30.3	5%	0.05	20%	0.2	C	C	.	.	H	α-helix	trans	-65.7	-38.9	177	0	0	0	0	0	112.5	G209 T210 L217 F352 L353	G209-A213 PolarHBondContact O-N 2.99Å; T210-A213 PolarHBondContact O-N 3.08Å; A213-L217 WeakPolarHBondContact O-CG 3.32Å; A213-L217 PolarHBondContact O-N 3.41Å; A213-L217 VanDerWaalsContact O-N 3.13Å; A213-F352 HydrophobicContact CB-CB 4.2Å; A213-L353 HydrophobicContact CB-CB 4.15Å; A213-L353 HydrophobicContact CB-CD1 4.19Å
214	V	93.7	Very high	91	Very high	69 Å²	69	36.4 Å²	36.4	42%	0.418	24%	0.243	S	C	.	.	H	α-helix	trans	-64	-44.9	172.8	172.7	0	0	0	0	110.5	T210 V211 L216 L217 V218 L353	T210-V214 WeakPolarHBondContact O-CG2 3.36Å; T210-V214 PolarHBondContact O-N 3.47Å; V211-V214 PolarHBondContact O-N 3.36Å; V214-L216 VanDerWaalsContact C-N 3.33Å; V214-L216 PolarHBondContact O-N 3.26Å; V214-L217 WeakPolarHBondContact O-CB 3.26Å; V214-L217 PolarHBondContact O-N 3.39Å; V214-L217 VanDerWaalsContact O-N 3.12Å; V214-V218 HydrophobicContact CG1-CG2 4.36Å; V214-V218 WeakPolarHBondContact O-CG2 3.16Å; V214-V218 PolarHBondContact O-N 3.25Å; V214-L353 HydrophobicContact CG2-CD1 3.66Å
215	A	90.7	Very high	90.6	Very high	17 Å²	17	39.7 Å²	39.7	14%	0.14	26%	0.26	C	S	.	.	H	α-helix	trans	-65.1	-37.6	-179.1	0	0	0	0	0	111.9	F70 V211 S212 L217 V218 D219 F233	F70-A215 HydrophobicContact CE1-CB 3.85Å; F70-A215 HydrophobicContact CZ-CB 4.39Å; V211-A215 WeakPolarHBondContact O-CB 3.43Å; V211-A215 PolarHBondContact O-N 2.91Å; S212-A215 PolarHBondContact O-N 2.93Å; A215-L217 PolarHBondContact O-N 3.03Å; A215-V218 PolarHBondContact O-N 2.6Å; A215-D219 WeakPolarHBondContact O-CB 3.15Å; A215-D219 PolarHBondContact O-N 3.19Å; A215-F233 HydrophobicContact CB-CE1 3.7Å
216	L	89.8	Confident	90.3	Very high	38 Å²	38	40.9 Å²	40.9	20%	0.199	27%	0.266	C	S	.	.	H	α-helix	trans	-58.8	-43.7	170.1	171.6	62.6	0	0	0	112	T73 S212 V214 D219 L220 P348 F352	T73-L216 HydrophobicContact CG2-CB 3.84Å; T73-L216 HydrophobicContact CG2-CD1 3.83Å; T73-L216 HydrophobicContact CG2-CG 4.32Å; S212-L216 WeakPolarHBondContact O-CB 3.33Å; S212-L216 PolarHBondContact O-N 3.19Å; V214-L216 VanDerWaalsContact C-N 3.33Å; V214-L216 PolarHBondContact O-N 3.26Å; L216-D219 PolarHBondContact O-N 2.98Å; L216-L220 VanDerWaalsContact O-CB 3.25Å; L216-L220 WeakPolarHBondContact O-CB 3.49Å; L216-L220 PolarHBondContact O-N 2.84Å; L216-P348 HydrophobicContact CD2-CB 4.34Å; L216-F352 HydrophobicContact CD2-CD2 3.95Å
217	L	91.8	Very high	90.1	Very high	23 Å²	23	43.8 Å²	43.8	12%	0.12	28%	0.276	C	S	.	.	H	α-helix	trans	-66.9	-39.9	178.4	-73.8	166.8	0	0	0	112.4	A213 V214 A215 L220 A221 F345 P348 L349 L353	A213-L217 WeakPolarHBondContact O-CG 3.32Å; A213-L217 PolarHBondContact O-N 3.41Å; A213-L217 VanDerWaalsContact O-N 3.13Å; V214-L217 WeakPolarHBondContact O-CB 3.26Å; V214-L217 PolarHBondContact O-N 3.39Å; V214-L217 VanDerWaalsContact O-N 3.12Å; A215-L217 PolarHBondContact O-N 3.03Å; L217-L220 PolarHBondContact O-N 2.94Å; L217-A221 WeakPolarHBondContact O-CB 3.24Å; L217-A221 PolarHBondContact O-N 3.22Å; L217-F345 HydrophobicContact CD2-CD1 3.83Å; L217-P348 HydrophobicContact CD2-CB 3.65Å; L217-P348 HydrophobicContact CG-CB 4.38Å; L217-L349 HydrophobicContact CD1-CD2 3.64Å; L217-L349 HydrophobicContact CD1-CG 4.43Å; L217-L349 HydrophobicContact CD2-CD2 3.95Å; L217-L349 HydrophobicContact CD2-CG 3.94Å; L217-L349 HydrophobicContact CG-CD2 4.48Å; L217-L353 HydrophobicContact CD1-CB 4.03Å; L217-L353 HydrophobicContact CD1-CD2 3.61Å; L217-L353 HydrophobicContact CD1-CG 4.31Å
218	V	90.9	Very high	89.8	Confident	88 Å²	88	45.2 Å²	45.2	53%	0.533	28%	0.284	S	S	.	.	H	α-helix	trans	-64.4	-46.2	175.9	171.8	0	0	0	0	110.4	V214 A215 L220 A221 A222	V214-V218 HydrophobicContact CG1-CG2 4.36Å; V214-V218 WeakPolarHBondContact O-CG2 3.16Å; V214-V218 PolarHBondContact O-N 3.25Å; A215-V218 PolarHBondContact O-N 2.6Å; V218-L220 PolarHBondContact O-N 3.44Å; V218-A221 PolarHBondContact O-N 2.77Å; V218-A222 WeakPolarHBondContact O-CB 3.44Å; V218-A222 PolarHBondContact O-N 3.34Å
219	D	87.5	Confident	89.7	Confident	23 Å²	23	46.1 Å²	46.1	12%	0.123	29%	0.291	C	S	.	.	H	α-helix	trans	-56	-52.5	174.9	178.8	44.4	0	0	0	110.7	A215 L216 A221 A222 S223 S229 F233	A215-D219 WeakPolarHBondContact O-CB 3.15Å; A215-D219 PolarHBondContact O-N 3.19Å; L216-D219 PolarHBondContact O-N 2.98Å; D219-A221 PolarHBondContact O-N 2.85Å; D219-A221 VanDerWaalsContact O-N 3.08Å; D219-A222 PolarHBondContact O-N 3.39Å; D219-S223 WeakPolarHBondContact O-CB 3.31Å; D219-S223 PolarHBondContact O-N 3.39Å; D219-S223 PolarHBondContact O-OG 3.06Å; D219-S223 WeakPolarHBondContact OD1-CB 3.46Å; D219-S223 PolarHBondContact OD1-OG 3.35Å; D219-S229 WeakPolarHBondContact OD1-CB 3.19Å; D219-S229 PolarHBondContact OD1-OG 2.7Å; D219-F233 HydrophobicContact CB-CE2 4.19Å; D219-F233 HydrophobicContact CB-CZ 3.81Å
220	L	87.1	Confident	89.6	Confident	30 Å²	30	46 Å²	46	16%	0.157	29%	0.289	C	S	.	.	H	α-helix	trans	-59.2	-26.8	179.2	-165.8	68.5	0	0	0	113.9	L216 L217 V218 K344 F345 P348	L216-L220 VanDerWaalsContact O-CB 3.25Å; L216-L220 WeakPolarHBondContact O-CB 3.49Å; L216-L220 PolarHBondContact O-N 2.84Å; L217-L220 PolarHBondContact O-N 2.94Å; V218-L220 PolarHBondContact O-N 3.44Å; L220-K344 HydrophobicContact CD1-CD 4.07Å; L220-K344 HydrophobicContact CD1-CG 4.16Å; L220-K344 HydrophobicContact CD2-CD 4.29Å; L220-K344 HydrophobicContact CD2-CG 4.06Å; L220-K344 HydrophobicContact CG-CD 3.9Å; L220-K344 HydrophobicContact CG-CG 4.15Å; L220-K344 PolarHBondContact O-NZ 3.2Å; L220-F345 HydrophobicContact CB-CE1 4.02Å; L220-F345 HydrophobicContact CD2-CD1 3.59Å; L220-F345 HydrophobicContact CD2-CE1 3.61Å; L220-F345 HydrophobicContact CD2-CG 4.44Å; L220-F345 HydrophobicContact CD2-CZ 4.46Å; L220-F345 HydrophobicContact CG-CD1 4.33Å; L220-F345 HydrophobicContact CG-CE1 3.83Å; L220-F345 HydrophobicContact CG-CZ 4.4Å; L220-P348 HydrophobicContact CD2-CG 4.11Å
221	A	89.1	Confident	89.5	Confident	73 Å²	73	46.9 Å²	46.9	60%	0.603	29%	0.293	S	S	*	.	H	α-helix	trans	-93.2	-31.8	-178.5	0	0	0	0	0	113.8	L217 V218 D219 F345	L217-A221 WeakPolarHBondContact O-CB 3.24Å; L217-A221 PolarHBondContact O-N 3.22Å; V218-A221 PolarHBondContact O-N 2.77Å; D219-A221 PolarHBondContact O-N 2.85Å; D219-A221 VanDerWaalsContact O-N 3.08Å; A221-F345 HydrophobicContact CB-CE1 4.21Å; A221-F345 HydrophobicContact CB-CZ 4.06Å
222	A	86.8	Confident	89.5	Confident	77 Å²	77	46.5 Å²	46.5	64%	0.636	30%	0.295	S	S	*	.	H	α-helix	trans	-124.2	-14.9	-165.2	0	0	0	0	0	114.8	V218 D219	V218-A222 WeakPolarHBondContact O-CB 3.44Å; V218-A222 PolarHBondContact O-N 3.34Å; D219-A222 PolarHBondContact O-N 3.39Å
223	S	82.7	Confident	89.5	Confident	48 Å²	48	46.5 Å²	46.5	34%	0.336	30%	0.295	S	S	.	.			trans	-78.9	130.6	-177.3	73.5	0	0	0	0	112.1	D219	D219-S223 WeakPolarHBondContact O-CB 3.31Å; D219-S223 PolarHBondContact O-N 3.39Å; D219-S223 PolarHBondContact O-OG 3.06Å; D219-S223 WeakPolarHBondContact OD1-CB 3.46Å; D219-S223 PolarHBondContact OD1-OG 3.35Å
224	S	82.4	Confident	89.5	Confident	128 Å²	128	46.2 Å²	46.2	90%	0.895	29%	0.292	S	S	*	.	S	Bend	trans	-106.2	-24.8	173.2	58	0	0	0	0	112.5
225	D	88.1	Confident	89.5	Confident	69 Å²	69	46.7 Å²	46.7	37%	0.369	29%	0.292	S	S	.	.			trans	-127.5	121.5	176.2	-169.9	-30.4	0	0	0	110	R227 D228 S229	D225-R227 VanDerWaalsContact C-N 3.28Å; D225-R227 PolarHBondContact O-N 2.87Å; D225-R227 WeakPolarHBondContact OD1-CB 3.41Å; D225-R227 PolarHBondContact OD1-N 2.9Å; D225-D228 HydrophobicContact CB-CB 4.43Å; D225-D228 PolarHBondContact O-N 2.94Å; D225-S229 PolarHBondContact O-N 3.22Å; D225-S229 VanDerWaalsContact O-N 3.14Å
226	V	87.9	Confident	89.6	Confident	34 Å²	34	49.6 Å²	49.6	21%	0.206	30%	0.304	C	S	.	.	H	α-helix	trans	-62.8	-33.2	-178.5	179.5	0	0	0	0	112.2	E76 T230	E76-V226 HydrophobicContact CB-CG1 3.83Å; E76-V226 HydrophobicContact CB-CG2 4.14Å; V226-T230 WeakPolarHBondContact O-CB 3.39Å; V226-T230 PolarHBondContact O-N 3.49Å; V226-T230 PolarHBondContact O-OG1 2.9Å
227	R	89.8	Confident	89.8	Confident	66 Å²	66	47.8 Å²	47.8	25%	0.249	29%	0.294	C	S	.	.	H	α-helix	trans	-70.6	-42.7	179.5	-66.9	174.3	60.8	-165.7	-1.2	111.6	Y80 V153 K154 D225 T230 L231	Y80-R227 HydrophobicContact CD1-CG 4.26Å; Y80-R227 HydrophobicContact CE1-CG 3.86Å; V153-R227 HydrophobicContact CG1-CB 4.33Å; V153-R227 WeakPolarHBondContact CG1-O 3.33Å; V153-R227 PolarHBondContact O-NE 3.24Å; V153-R227 PolarHBondContact O-NH2 3.38Å; K154-R227 PolarHBondContact O-NH2 2.66Å; D225-R227 VanDerWaalsContact C-N 3.28Å; D225-R227 PolarHBondContact O-N 2.87Å; D225-R227 WeakPolarHBondContact OD1-CB 3.41Å; D225-R227 PolarHBondContact OD1-N 2.9Å; R227-T230 PolarHBondContact O-N 2.97Å; R227-L231 WeakPolarHBondContact O-CB 3.48Å; R227-L231 PolarHBondContact O-N 3.26Å
228	D	89.7	Confident	90	Very high	84 Å²	84	47.3 Å²	47.3	45%	0.449	29%	0.294	S	S	.	.	H	α-helix	trans	-71.6	-37.2	-179.1	-74.7	-17.8	0	0	0	111.2	K154 D225 L231 A232	K154-D228 IonicContact NZ-OD1 3Å; K154-D228 PolarHBondContact NZ-OD1 3.37Å; D225-D228 HydrophobicContact CB-CB 4.43Å; D225-D228 PolarHBondContact O-N 2.94Å; D228-L231 PolarHBondContact O-N 2.97Å; D228-A232 PolarHBondContact O-N 3.15Å
229	S	89.7	Confident	90.1	Very high	19 Å²	19	48 Å²	48	13%	0.133	30%	0.298	C	S	.	.	H	α-helix	trans	-58	-48.3	169.3	173.4	0	0	0	0	112.2	D219 D225 L231 A232 F233	D219-S229 WeakPolarHBondContact OD1-CB 3.19Å; D219-S229 PolarHBondContact OD1-OG 2.7Å; D225-S229 PolarHBondContact O-N 3.22Å; D225-S229 VanDerWaalsContact O-N 3.14Å; S229-L231 PolarHBondContact O-N 2.89Å; S229-A232 WeakPolarHBondContact O-CB 3.37Å; S229-A232 PolarHBondContact O-N 3.24Å; S229-A232 VanDerWaalsContact O-N 3.11Å; S229-F233 WeakPolarHBondContact O-CD2 3.22Å; S229-F233 PolarHBondContact O-N 3.47Å; S229-F233 WeakPolarHBondContact OG-CE2 3.23Å
230	T	91.2	Very high	90.4	Very high	2 Å²	2	50 Å²	50	1%	0.012	31%	0.306	C	S	.	.	H	α-helix	trans	-65.6	-38.8	179.1	-58.7	0	0	0	0	112.7	A74 Y77 V153 V226 R227 A232 F233 F234	A74-T230 HydrophobicContact CB-CG2 4.04Å; Y77-T230 WeakPolarHBondContact CB-OG1 3.42Å; Y77-T230 HydrophobicContact CD1-CG2 3.68Å; Y77-T230 HydrophobicContact CD2-CG2 4.02Å; Y77-T230 HydrophobicContact CE1-CG2 4.04Å; Y77-T230 HydrophobicContact CE2-CG2 4.37Å; Y77-T230 HydrophobicContact CG-CG2 3.67Å; V153-T230 HydrophobicContact CG2-CG2 3.91Å; V226-T230 WeakPolarHBondContact O-CB 3.39Å; V226-T230 PolarHBondContact O-N 3.49Å; V226-T230 PolarHBondContact O-OG1 2.9Å; R227-T230 PolarHBondContact O-N 2.97Å; T230-A232 VanDerWaalsContact C-N 3.27Å; T230-A232 PolarHBondContact O-N 3.12Å; T230-F233 PolarHBondContact O-N 3.21Å; T230-F234 HydrophobicContact CG2-CD1 4.45Å; T230-F234 HydrophobicContact CG2-CD2 3.94Å; T230-F234 HydrophobicContact CG2-CE1 4.03Å; T230-F234 HydrophobicContact CG2-CE2 3.48Å; T230-F234 VanDerWaalsContact CG2-CE2 3.48Å; T230-F234 HydrophobicContact CG2-CG 4.41Å; T230-F234 HydrophobicContact CG2-CZ 3.52Å; T230-F234 WeakPolarHBondContact O-CG 3.4Å; T230-F234 PolarHBondContact O-N 3.25Å
231	L	93.3	Very high	90.8	Very high	32 Å²	32	48.8 Å²	48.8	17%	0.168	30%	0.299	C	S	.	.	H	α-helix	trans	-58.3	-44	173.2	-165.8	86.5	0	0	0	110.4	I150 V153 K154 R227 D228 S229 F234 L235	I150-L231 HydrophobicContact CG2-CD1 4.04Å; V153-L231 HydrophobicContact CB-CD1 4.22Å; V153-L231 HydrophobicContact CG1-CB 4.21Å; V153-L231 HydrophobicContact CG1-CD1 4.02Å; K154-L231 HydrophobicContact CG-CD1 4.3Å; R227-L231 WeakPolarHBondContact O-CB 3.48Å; R227-L231 PolarHBondContact O-N 3.26Å; D228-L231 PolarHBondContact O-N 2.97Å; S229-L231 PolarHBondContact O-N 2.89Å; L231-F234 PolarHBondContact O-N 3.2Å; L231-L235 HydrophobicContact CD2-CD1 4.01Å; L231-L235 HydrophobicContact CG-CD1 3.89Å; L231-L235 HydrophobicContact CG-CG 4.45Å; L231-L235 VanDerWaalsContact O-CB 3.29Å; L231-L235 WeakPolarHBondContact O-CB 2.89Å; L231-L235 VanDerWaalsContact O-CG 3.25Å; L231-L235 WeakPolarHBondContact O-CG 3.43Å; L231-L235 PolarHBondContact O-N 3.27Å
232	A	91.8	Very high	91.1	Very high	44 Å²	44	46.9 Å²	46.9	36%	0.364	29%	0.287	S	S	.	.	H	α-helix	trans	-62.3	-45	176.8	0	0	0	0	0	111.6	D228 S229 T230 F234 L235 M236	D228-A232 PolarHBondContact O-N 3.15Å; S229-A232 WeakPolarHBondContact O-CB 3.37Å; S229-A232 PolarHBondContact O-N 3.24Å; S229-A232 VanDerWaalsContact O-N 3.11Å; T230-A232 VanDerWaalsContact C-N 3.27Å; T230-A232 PolarHBondContact O-N 3.12Å; A232-F234 PolarHBondContact O-N 3.16Å; A232-L235 PolarHBondContact O-N 2.97Å; A232-M236 HydrophobicContact CB-CE 4.35Å; A232-M236 WeakPolarHBondContact O-CB 3.44Å; A232-M236 WeakPolarHBondContact O-CE 3.34Å; A232-M236 VanDerWaalsContact O-CG 3.29Å; A232-M236 WeakPolarHBondContact O-CG 3.33Å; A232-M236 PolarHBondContact O-N 2.95Å
233	F	91.8	Very high	91.6	Very high	6 Å²	6	47.2 Å²	47.2	3%	0.026	28%	0.278	C	S	.	.	H	α-helix	trans	-57.5	-48.8	175.1	-75.3	-49.3	0	0	0	112.5	F70 T73 A215 D219 S229 T230 M236 A237	F70-F233 HydrophobicContact CB-CB 4.15Å; F70-F233 HydrophobicContact CB-CD1 4.4Å; F70-F233 AromaticContact CD1-CD1 3.73Å; F70-F233 HydrophobicContact CD1-CD1 3.73Å; F70-F233 HydrophobicContact CD1-CE1 4.17Å; F70-F233 HydrophobicContact CD2-CD1 4.38Å; F70-F233 VanDerWaalsContact CD2-O 3.27Å; F70-F233 WeakPolarHBondContact CD2-O 3.08Å; F70-F233 HydrophobicContact CE1-CD1 4.01Å; F70-F233 HydrophobicContact CE1-CE1 4.24Å; F70-F233 HydrophobicContact CG-CB 4.35Å; F70-F233 AromaticContact CG-CD1 3.93Å; F70-F233 HydrophobicContact CG-CD1 3.93Å; F70-F233 HydrophobicContact CZ-CD1 4.47Å; T73-F233 HydrophobicContact CG2-CE2 4.35Å; T73-F233 HydrophobicContact CG2-CZ 4.03Å; A215-F233 HydrophobicContact CB-CE1 3.7Å; D219-F233 HydrophobicContact CB-CE2 4.19Å; D219-F233 HydrophobicContact CB-CZ 3.81Å; S229-F233 WeakPolarHBondContact O-CD2 3.22Å; S229-F233 PolarHBondContact O-N 3.47Å; S229-F233 WeakPolarHBondContact OG-CE2 3.23Å; T230-F233 PolarHBondContact O-N 3.21Å; F233-M236 HydrophobicContact CD1-CE 4.04Å; F233-M236 PolarHBondContact O-N 3.46Å; F233-A237 WeakPolarHBondContact O-CB 3.31Å; F233-A237 PolarHBondContact O-N 3.13Å
234	F	93.8	Very high	92.2	Very high	0 Å²	0	45 Å²	45	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-71.3	-35.6	-178.3	-64.6	-12	0	0	0	112.8	F71 W78 F146 M149 I150 V153 T230 L231 A232 A237 A238	F71-F234 HydrophobicContact CD2-CE1 4.09Å; F71-F234 HydrophobicContact CD2-CZ 4.27Å; F71-F234 HydrophobicContact CE2-CZ 4.46Å; W78-F234 HydrophobicContact CH2-CE2 4.42Å; W78-F234 AromaticContact CH2-CZ 3.77Å; W78-F234 HydrophobicContact CH2-CZ 3.77Å; W78-F234 AromaticContact CZ2-CZ 3.83Å; W78-F234 HydrophobicContact CZ2-CZ 3.83Å; F146-F234 HydrophobicContact CD1-CB 4.14Å; F146-F234 HydrophobicContact CD1-CD1 4.26Å; F146-F234 HydrophobicContact CD1-CG 4.34Å; F146-F234 AromaticContact CE1-CD1 3.9Å; F146-F234 HydrophobicContact CE1-CD1 3.9Å; F146-F234 HydrophobicContact CE1-CG 4.43Å; M149-F234 HydrophobicContact CB-CD2 3.77Å; M149-F234 HydrophobicContact CB-CE2 3.84Å; M149-F234 HydrophobicContact CB-CG 4.49Å; M149-F234 HydrophobicContact CE-CE2 4.03Å; M149-F234 HydrophobicContact CE-CZ 4.32Å; I150-F234 HydrophobicContact CD1-CB 4.44Å; I150-F234 HydrophobicContact CG1-CB 3.64Å; V153-F234 HydrophobicContact CG2-CD2 3.69Å; V153-F234 HydrophobicContact CG2-CE2 3.67Å; T230-F234 HydrophobicContact CG2-CD1 4.45Å; T230-F234 HydrophobicContact CG2-CD2 3.94Å; T230-F234 HydrophobicContact CG2-CE1 4.03Å; T230-F234 HydrophobicContact CG2-CE2 3.48Å; T230-F234 VanDerWaalsContact CG2-CE2 3.48Å; T230-F234 HydrophobicContact CG2-CG 4.41Å; T230-F234 HydrophobicContact CG2-CZ 3.52Å; T230-F234 WeakPolarHBondContact O-CG 3.4Å; T230-F234 PolarHBondContact O-N 3.25Å; L231-F234 PolarHBondContact O-N 3.2Å; A232-F234 PolarHBondContact O-N 3.16Å; F234-A237 PolarHBondContact O-N 3.5Å; F234-A238 WeakPolarHBondContact O-CB 3.34Å; F234-A238 PolarHBondContact O-N 3.5Å
235	L	94.2	Very high	92.9	Very high	79 Å²	79	40.9 Å²	40.9	41%	0.414	23%	0.229	S	C	.	.	H	α-helix	trans	-64.1	-45.5	172.9	-77	168.1	0	0	0	111.5	I150 L231 A232 A237 A238 V239	I150-L235 HydrophobicContact CD1-CD2 3.88Å; I150-L235 HydrophobicContact CD1-CG 4.29Å; I150-L235 HydrophobicContact CG1-CD2 4.48Å; I150-L235 HydrophobicContact CG2-CD2 4.39Å; L231-L235 HydrophobicContact CD2-CD1 4.01Å; L231-L235 HydrophobicContact CG-CD1 3.89Å; L231-L235 HydrophobicContact CG-CG 4.45Å; L231-L235 VanDerWaalsContact O-CB 3.29Å; L231-L235 WeakPolarHBondContact O-CB 2.89Å; L231-L235 VanDerWaalsContact O-CG 3.25Å; L231-L235 WeakPolarHBondContact O-CG 3.43Å; L231-L235 PolarHBondContact O-N 3.27Å; A232-L235 PolarHBondContact O-N 2.97Å; L235-A237 VanDerWaalsContact C-N 3.32Å; L235-A237 PolarHBondContact O-N 2.85Å; L235-A238 PolarHBondContact O-N 3.35Å; L235-V239 WeakPolarHBondContact O-CG2 3.35Å; L235-V239 PolarHBondContact O-N 2.86Å
236	M	92.4	Very high	93.3	Very high	78 Å²	78	39.5 Å²	39.5	38%	0.384	23%	0.231	S	C	.	.	H	α-helix	trans	-60.7	-42.9	175.9	-74.4	-172.8	-76.5	0	0	111.2	F70 A232 F233 A238 V239 F240	F70-M236 HydrophobicContact CD2-CB 4.3Å; F70-M236 HydrophobicContact CE2-CB 3.64Å; F70-M236 HydrophobicContact CE2-CE 4.38Å; F70-M236 HydrophobicContact CZ-CE 4.38Å; A232-M236 HydrophobicContact CB-CE 4.35Å; A232-M236 WeakPolarHBondContact O-CB 3.44Å; A232-M236 WeakPolarHBondContact O-CE 3.34Å; A232-M236 VanDerWaalsContact O-CG 3.29Å; A232-M236 WeakPolarHBondContact O-CG 3.33Å; A232-M236 PolarHBondContact O-N 2.95Å; F233-M236 HydrophobicContact CD1-CE 4.04Å; F233-M236 PolarHBondContact O-N 3.46Å; M236-A238 PolarHBondContact O-N 3.38Å; M236-V239 PolarHBondContact O-N 3.17Å; M236-F240 WeakPolarHBondContact O-CD2 3.36Å; M236-F240 PolarHBondContact O-N 3.01Å
237	A	93.8	Very high	93.8	Very high	0 Å²	0	39.3 Å²	39.3	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-58.5	-46.8	174.1	0	0	0	0	0	112.2	P67 F70 F146 F233 F234 L235 V239 F240 L241	P67-A237 HydrophobicContact CB-CB 4.04Å; F70-A237 HydrophobicContact CD2-CB 4.16Å; F146-A237 HydrophobicContact CD1-CB 3.64Å; F146-A237 HydrophobicContact CE1-CB 3.41Å; F146-A237 VanDerWaalsContact CE1-CB 3.41Å; F146-A237 HydrophobicContact CE2-CB 4.38Å; F146-A237 HydrophobicContact CG-CB 4.23Å; F146-A237 HydrophobicContact CZ-CB 3.84Å; F233-A237 WeakPolarHBondContact O-CB 3.31Å; F233-A237 PolarHBondContact O-N 3.13Å; F234-A237 PolarHBondContact O-N 3.5Å; L235-A237 VanDerWaalsContact C-N 3.32Å; L235-A237 PolarHBondContact O-N 2.85Å; A237-V239 PolarHBondContact O-N 3.03Å; A237-F240 PolarHBondContact O-N 2.93Å; A237-L241 WeakPolarHBondContact O-CB 3.2Å; A237-L241 WeakPolarHBondContact O-CG 3.3Å; A237-L241 PolarHBondContact O-N 3.2Å
238	A	95.2	Very high	94.1	Very high	14 Å²	14	36.3 Å²	36.3	12%	0.116	22%	0.217	C	C	.	.	H	α-helix	trans	-62.3	-43.4	178.8	0	0	0	0	0	112.5	L143 F146 I150 F234 L235 M236 L241 G242	L143-A238 HydrophobicContact CD1-CB 3.91Å; L143-A238 WeakPolarHBondContact CD1-O 2.97Å; F146-A238 HydrophobicContact CB-CB 4.35Å; I150-A238 HydrophobicContact CD1-CB 4.04Å; F234-A238 WeakPolarHBondContact O-CB 3.34Å; F234-A238 PolarHBondContact O-N 3.5Å; L235-A238 PolarHBondContact O-N 3.35Å; M236-A238 PolarHBondContact O-N 3.38Å; A238-L241 PolarHBondContact O-N 3.33Å; A238-G242 PolarHBondContact O-N 3.21Å
239	V	94.6	Very high	94.4	Very high	102 Å²	102	35.7 Å²	35.7	62%	0.618	21%	0.213	S	C	*	.	H	α-helix	trans	-62.2	-45	176.4	170.7	0	0	0	0	111	L235 M236 A237 L241 G242 L243	L235-V239 WeakPolarHBondContact O-CG2 3.35Å; L235-V239 PolarHBondContact O-N 2.86Å; M236-V239 PolarHBondContact O-N 3.17Å; A237-V239 PolarHBondContact O-N 3.03Å; V239-L241 PolarHBondContact O-N 3.31Å; V239-G242 PolarHBondContact O-N 3.46Å; V239-L243 WeakPolarHBondContact O-CB 3.31Å; V239-L243 PolarHBondContact O-N 2.87Å
240	F	93.4	Very high	94.6	Very high	65 Å²	65	38.7 Å²	38.7	29%	0.285	23%	0.228	S	C	.	.	H	α-helix	trans	-65.3	-37.2	177.7	-96.1	-93	0	0	0	112.8	I62 L66 M236 A237 L243 C244	I62-F240 HydrophobicContact CG2-CD1 4.03Å; I62-F240 HydrophobicContact CG2-CE1 3.76Å; L66-F240 HydrophobicContact CD2-CB 4.19Å; L66-F240 HydrophobicContact CD2-CD1 3.96Å; L66-F240 HydrophobicContact CD2-CD2 3.75Å; L66-F240 HydrophobicContact CD2-CE1 4.26Å; L66-F240 HydrophobicContact CD2-CE2 4.06Å; L66-F240 HydrophobicContact CD2-CG 3.68Å; L66-F240 HydrophobicContact CD2-CZ 4.3Å; M236-F240 WeakPolarHBondContact O-CD2 3.36Å; M236-F240 PolarHBondContact O-N 3.01Å; A237-F240 PolarHBondContact O-N 2.93Å; F240-L243 PolarHBondContact O-N 3.21Å; F240-C244 WeakPolarHBondContact O-CB 3.49Å; F240-C244 PolarHBondContact O-N 2.65Å; F240-C244 PolarHBondContact O-SG 2.97Å
241	L	95.2	Very high	94.8	Very high	4 Å²	4	38.6 Å²	38.6	2%	0.021	23%	0.227	C	C	.	.	H	α-helix	trans	-63.7	-43.9	173.6	-75.9	170.7	0	0	0	111.6	P67 L139 L143 F146 A237 A238 V239 C244 M245	P67-L241 HydrophobicContact CB-CD1 4.34Å; P67-L241 HydrophobicContact CG-CD1 4.17Å; P67-L241 HydrophobicContact CG-CD2 3.85Å; P67-L241 HydrophobicContact CG-CG 3.83Å; L139-L241 HydrophobicContact CD2-CD2 3.79Å; L143-L241 HydrophobicContact CD1-CB 4.21Å; F146-L241 HydrophobicContact CD2-CD1 3.58Å; F146-L241 HydrophobicContact CE2-CD1 4.13Å; F146-L241 HydrophobicContact CG-CD1 4.31Å; A237-L241 WeakPolarHBondContact O-CB 3.2Å; A237-L241 WeakPolarHBondContact O-CG 3.3Å; A237-L241 PolarHBondContact O-N 3.2Å; A238-L241 PolarHBondContact O-N 3.33Å; V239-L241 PolarHBondContact O-N 3.31Å; L241-C244 PolarHBondContact O-N 3.48Å; L241-M245 PolarHBondContact O-N 3.38Å
242	G	96.1	Very high	94.6	Very high	33 Å²	33	38.6 Å²	38.6	34%	0.34	23%	0.23	S	C	.	.	H	α-helix	trans	-61.1	-43.1	174	0	0	0	0	0	112.5	A238 V239 M245 G246	A238-G242 PolarHBondContact O-N 3.21Å; V239-G242 PolarHBondContact O-N 3.46Å; G242-M245 WeakPolarHBondContact O-CB 3.33Å; G242-M245 PolarHBondContact O-N 2.7Å; G242-G246 PolarHBondContact O-N 3.19Å
243	L	96.1	Very high	94.5	Very high	85 Å²	85	42.4 Å²	42.4	45%	0.445	24%	0.24	S	C	.	.	H	α-helix	trans	-60.6	-45.4	174.2	178.6	63.4	0	0	0	111.5	V239 F240 M245 G246 L247	V239-L243 WeakPolarHBondContact O-CB 3.31Å; V239-L243 PolarHBondContact O-N 2.87Å; F240-L243 PolarHBondContact O-N 3.21Å; L243-M245 VanDerWaalsContact C-N 3.29Å; L243-M245 PolarHBondContact O-N 3.06Å; L243-G246 PolarHBondContact O-N 3.32Å; L243-L247 HydrophobicContact CD1-CD1 4.04Å; L243-L247 HydrophobicContact CD1-CD2 4.49Å; L243-L247 HydrophobicContact CD1-CG 4Å; L243-L247 HydrophobicContact CD2-CD1 4.44Å; L243-L247 HydrophobicContact CG-CD1 3.86Å; L243-L247 HydrophobicContact CG-CG 4.23Å; L243-L247 WeakPolarHBondContact O-CB 3.46Å; L243-L247 VanDerWaalsContact O-CG 3.29Å; L243-L247 WeakPolarHBondContact O-CG 3.42Å; L243-L247 PolarHBondContact O-N 2.97Å
244	C	96.7	Very high	94.5	Very high	1 Å²	1	44.4 Å²	44.4	1%	0.007	25%	0.251	C	S	.	.	H	α-helix	trans	-61	-38.7	177.2	-71.2	0	0	0	0	112.2	L60 G63 L139 F240 L241 Y248	L60-C244 HydrophobicContact CD2-CB 3.91Å; L60-C244 WeakPolarHBondContact CD2-O 3.2Å; G63-C244 VanDerWaalsContact CA-SG 3.59Å; L139-C244 HydrophobicContact CD1-CB 4.35Å; L139-C244 HydrophobicContact CD2-CB 4.2Å; F240-C244 WeakPolarHBondContact O-CB 3.49Å; F240-C244 PolarHBondContact O-N 2.65Å; F240-C244 PolarHBondContact O-SG 2.97Å; L241-C244 PolarHBondContact O-N 3.48Å; C244-Y248 VanDerWaalsContact O-CB 3.31Å; C244-Y248 WeakPolarHBondContact O-CB 3.21Å; C244-Y248 PolarHBondContact O-N 3.39Å
245	M	96.3	Very high	94.3	Very high	42 Å²	42	50.6 Å²	50.6	21%	0.207	28%	0.28	C	S	.	.	H	α-helix	trans	-62.4	-47.9	174.9	-173.3	178.5	-78.8	0	0	111.3	L136 L139 S140 L241 G242 L243 Y248 L249	L136-M245 HydrophobicContact CD2-CG 3.85Å; L139-M245 HydrophobicContact CB-CE 3.88Å; L139-M245 HydrophobicContact CD1-CB 4.17Å; S140-M245 WeakPolarHBondContact OG-CE 3.47Å; L241-M245 PolarHBondContact O-N 3.38Å; G242-M245 WeakPolarHBondContact O-CB 3.33Å; G242-M245 PolarHBondContact O-N 2.7Å; L243-M245 VanDerWaalsContact C-N 3.29Å; L243-M245 PolarHBondContact O-N 3.06Å; M245-Y248 PolarHBondContact O-N 2.97Å; M245-L249 WeakPolarHBondContact O-CG 3.34Å; M245-L249 PolarHBondContact O-N 2.95Å; M245-L249 VanDerWaalsContact O-N 3.09Å
246	G	96.7	Very high	94.2	Very high	39 Å²	39	47.2 Å²	47.2	40%	0.402	26%	0.262	S	S	.	.	H	α-helix	trans	-62.1	-44.7	176.7	0	0	0	0	0	113.2	G242 L243 Y248 L249 L250	G242-G246 PolarHBondContact O-N 3.19Å; L243-G246 PolarHBondContact O-N 3.32Å; G246-Y248 PolarHBondContact O-N 3.08Å; G246-L249 PolarHBondContact O-N 2.97Å; G246-L250 PolarHBondContact O-N 3.33Å
247	L	96.9	Very high	94.1	Very high	31 Å²	31	43.5 Å²	43.5	16%	0.162	24%	0.243	C	C	.	.	H	α-helix	trans	-65.9	-37.1	178.4	-69.2	177.3	0	0	0	112.3	I56 C59 L243 L250 L251	I56-L247 HydrophobicContact CG1-CB 4.49Å; I56-L247 HydrophobicContact CG1-CD2 4.31Å; I56-L247 HydrophobicContact CG2-CB 4.08Å; C59-L247 HydrophobicContact CB-CD1 3.4Å; L243-L247 HydrophobicContact CD1-CD1 4.04Å; L243-L247 HydrophobicContact CD1-CD2 4.49Å; L243-L247 HydrophobicContact CD1-CG 4Å; L243-L247 HydrophobicContact CD2-CD1 4.44Å; L243-L247 HydrophobicContact CG-CD1 3.86Å; L243-L247 HydrophobicContact CG-CG 4.23Å; L243-L247 WeakPolarHBondContact O-CB 3.46Å; L243-L247 VanDerWaalsContact O-CG 3.29Å; L243-L247 WeakPolarHBondContact O-CG 3.42Å; L243-L247 PolarHBondContact O-N 2.97Å; L247-L250 PolarHBondContact O-N 3.09Å; L247-L251 PolarHBondContact O-N 3.31Å
248	Y	96.3	Very high	93.9	Very high	2 Å²	2	50.1 Å²	50.1	1%	0.008	27%	0.268	C	S	.	.	H	α-helix	trans	-65.9	-41.3	175	-177.5	-100.2	0	0	0	112.1	L60 H132 V135 L136 L189 C244 M245 G246 L250 L251 S252	L60-Y248 HydrophobicContact CD1-CD2 4.25Å; H132-Y248 VanDerWaalsContact CA-OH 3.26Å; H132-Y248 WeakPolarHBondContact CA-OH 3.28Å; H132-Y248 HydrophobicContact CB-CE1 4.42Å; H132-Y248 AromaticContact CE1-CE1 3.96Å; H132-Y248 AromaticContact CG-CE1 3.85Å; H132-Y248 AromaticContact ND1-CE1 3.79Å; V135-Y248 HydrophobicContact CB-CD1 4.35Å; V135-Y248 HydrophobicContact CB-CD2 4.49Å; V135-Y248 HydrophobicContact CB-CE1 3.96Å; V135-Y248 HydrophobicContact CB-CE2 4.1Å; V135-Y248 HydrophobicContact CG1-CD1 3.7Å; V135-Y248 HydrophobicContact CG1-CD2 3.66Å; V135-Y248 HydrophobicContact CG1-CE1 3.82Å; V135-Y248 HydrophobicContact CG1-CE2 3.77Å; V135-Y248 HydrophobicContact CG1-CG 3.63Å; V135-Y248 HydrophobicContact CG2-CE2 4.08Å; L136-Y248 HydrophobicContact CD2-CD1 3.97Å; L136-Y248 HydrophobicContact CG-CD1 4.31Å; L136-Y248 HydrophobicContact CG-CE1 4.44Å; L189-Y248 HydrophobicContact CD2-CE2 4.12Å; C244-Y248 VanDerWaalsContact O-CB 3.31Å; C244-Y248 WeakPolarHBondContact O-CB 3.21Å; C244-Y248 PolarHBondContact O-N 3.39Å; M245-Y248 PolarHBondContact O-N 2.97Å; G246-Y248 PolarHBondContact O-N 3.08Å; Y248-L250 VanDerWaalsContact C-N 3.31Å; Y248-L250 PolarHBondContact O-N 3.45Å; Y248-L251 HydrophobicContact CD2-CD2 4.4Å; Y248-L251 WeakPolarHBondContact O-CB 3.39Å; Y248-L251 PolarHBondContact O-N 2.83Å; Y248-S252 PolarHBondContact O-N 3.46Å
249	L	95.9	Very high	93.6	Very high	71 Å²	71	52.1 Å²	52.1	37%	0.372	27%	0.273	S	S	.	.	H	α-helix	trans	-61.3	-41.7	173.3	-70.5	173	0	0	0	111.2	L136 M245 G246 L251 S252	L136-L249 HydrophobicContact CD1-CD2 4.05Å; L136-L249 HydrophobicContact CD2-CD2 4.18Å; L136-L249 HydrophobicContact CD2-CG 4.31Å; M245-L249 WeakPolarHBondContact O-CG 3.34Å; M245-L249 PolarHBondContact O-N 2.95Å; M245-L249 VanDerWaalsContact O-N 3.09Å; G246-L249 PolarHBondContact O-N 2.97Å; L249-L251 VanDerWaalsContact C-N 3.35Å; L249-L251 PolarHBondContact O-N 3.31Å; L249-S252 PolarHBondContact O-N 2.95Å; L249-S252 PolarHBondContact O-OG 2.98Å
250	L	95.7	Very high	93.3	Very high	82 Å²	82	47.9 Å²	47.9	43%	0.429	25%	0.246	S	C	.	.	H	α-helix	trans	-62.9	-39.7	174.5	-177.2	62.7	0	0	0	112.1	I56 G246 L247 Y248 S252 Q253 L254	I56-L250 HydrophobicContact CD1-CB 4.47Å; I56-L250 HydrophobicContact CD1-CD2 4.25Å; I56-L250 HydrophobicContact CD1-CG 4.25Å; G246-L250 PolarHBondContact O-N 3.33Å; L247-L250 PolarHBondContact O-N 3.09Å; Y248-L250 VanDerWaalsContact C-N 3.31Å; Y248-L250 PolarHBondContact O-N 3.45Å; L250-S252 VanDerWaalsContact C-N 3.28Å; L250-S252 PolarHBondContact O-N 2.97Å; L250-Q253 WeakPolarHBondContact O-CB 3.26Å; L250-Q253 PolarHBondContact O-N 2.96Å; L250-L254 PolarHBondContact O-N 3.09Å
251	L	94.6	Very high	93	Very high	0 Å²	0	47.5 Å²	47.5	0%	0	25%	0.246	C	C	.	.	H	α-helix	trans	-55.8	-44.5	176.5	-172.8	66.2	0	0	0	111.2	A53 I56 F57 L189 L247 Y248 L249 Q253 L254 A257 M261	A53-L251 HydrophobicContact CB-CD1 4.09Å; I56-L251 HydrophobicContact CB-CD1 4.37Å; I56-L251 HydrophobicContact CD1-CB 4.22Å; I56-L251 HydrophobicContact CD1-CD1 4.21Å; I56-L251 HydrophobicContact CG2-CB 4.01Å; I56-L251 HydrophobicContact CG2-CD1 4.16Å; I56-L251 HydrophobicContact CG2-CD2 4.36Å; I56-L251 HydrophobicContact CG2-CG 4.4Å; F57-L251 HydrophobicContact CE1-CD2 4.11Å; F57-L251 HydrophobicContact CE2-CD1 4.19Å; F57-L251 HydrophobicContact CE2-CD2 4.26Å; F57-L251 HydrophobicContact CZ-CD2 3.82Å; L189-L251 HydrophobicContact CD2-CD2 4.21Å; L247-L251 PolarHBondContact O-N 3.31Å; Y248-L251 HydrophobicContact CD2-CD2 4.4Å; Y248-L251 WeakPolarHBondContact O-CB 3.39Å; Y248-L251 PolarHBondContact O-N 2.83Å; L249-L251 VanDerWaalsContact C-N 3.35Å; L249-L251 PolarHBondContact O-N 3.31Å; L251-Q253 PolarHBondContact O-N 2.91Å; L251-Q253 VanDerWaalsContact O-N 3.11Å; L251-L254 HydrophobicContact CD1-CD1 4.3Å; L251-L254 PolarHBondContact O-N 3.05Å; L251-L254 VanDerWaalsContact O-N 3.1Å; L251-A257 HydrophobicContact CD1-CB 3.83Å; L251-A257 HydrophobicContact CG-CB 4.02Å; L251-A257 WeakPolarHBondContact O-CB 3.48Å; L251-M261 HydrophobicContact CG-CE 4.39Å
252	S	88.3	Confident	92.3	Very high	33 Å²	33	55 Å²	55	23%	0.231	27%	0.274	C	S	.	.	H	α-helix	trans	-60.2	-22.8	178.8	78.4	0	0	0	0	113.3	Y248 L249 L250 R258	Y248-S252 PolarHBondContact O-N 3.46Å; L249-S252 PolarHBondContact O-N 2.95Å; L249-S252 PolarHBondContact O-OG 2.98Å; L250-S252 VanDerWaalsContact C-N 3.28Å; L250-S252 PolarHBondContact O-N 2.97Å; S252-R258 WeakPolarHBondContact O-CG 3.45Å; S252-R258 PolarHBondContact O-NE 3.27Å
253	Q	90.5	Very high	91	Very high	123 Å²	123	59.6 Å²	59.6	58%	0.575	30%	0.298	S	S	*	.	H	α-helix	trans	-89.6	-17.3	179.8	-61.2	-175.1	-1.1	0	0	113.4	L250 L251 E255 R258	L250-Q253 WeakPolarHBondContact O-CB 3.26Å; L250-Q253 PolarHBondContact O-N 2.96Å; L251-Q253 PolarHBondContact O-N 2.91Å; L251-Q253 VanDerWaalsContact O-N 3.11Å; Q253-E255 PolarHBondContact O-N 2.87Å; Q253-R258 PolarHBondContact O-NE 3.08Å; Q253-R258 PolarHBondContact O-NH2 2.84Å
254	L	92.1	Very high	89.5	Confident	49 Å²	49	58.5 Å²	58.5	26%	0.257	30%	0.295	S	S	.	.			trans	-70.3	130.4	179	-65.5	177.4	0	0	0	111.3	A53 I56 L250 L251 Y256 A257 R258	A53-L254 HydrophobicContact CB-CD1 4.27Å; I56-L254 HydrophobicContact CD1-CD1 3.75Å; L250-L254 PolarHBondContact O-N 3.09Å; L251-L254 HydrophobicContact CD1-CD1 4.3Å; L251-L254 PolarHBondContact O-N 3.05Å; L251-L254 VanDerWaalsContact O-N 3.1Å; L254-Y256 PolarHBondContact O-N 2.95Å; L254-A257 HydrophobicContact CB-CB 4.08Å; L254-A257 PolarHBondContact O-N 3.46Å; L254-A257 VanDerWaalsContact O-N 3.09Å; L254-R258 WeakPolarHBondContact O-CG 3.29Å; L254-R258 PolarHBondContact O-N 3.16Å
255	E	89.8	Confident	87.4	Confident	130 Å²	130	62 Å²	62	61%	0.607	32%	0.324	S	S	*	.	H	α-helix	trans	-56.3	-41.8	176.9	-66.9	-179	168.5	0	0	111.8	Q253 A257 R258 Y259	Q253-E255 PolarHBondContact O-N 2.87Å; E255-A257 PolarHBondContact O-N 3.38Å; E255-R258 PolarHBondContact O-N 2.97Å; E255-Y259 PolarHBondContact O-N 3.14Å
256	Y	91.5	Very high	85.2	Confident	8 Å²	8	65 Å²	65	3%	0.031	35%	0.346	C	S	.	.	H	α-helix	trans	-53.1	-51.5	173.6	-178.5	-92.5	0	0	0	111.8	P46 D48 A53 F193 P194 N197 L254 Y259 Y260	P46-Y256 WeakPolarHBondContact O-CD2 3.26Å; P46-Y256 WeakPolarHBondContact O-CE2 3.33Å; D48-Y256 HydrophobicContact CB-CD1 4.38Å; D48-Y256 HydrophobicContact CB-CD2 3.83Å; D48-Y256 HydrophobicContact CB-CE1 4.28Å; D48-Y256 HydrophobicContact CB-CE2 3.7Å; D48-Y256 HydrophobicContact CB-CG 4.14Å; A53-Y256 HydrophobicContact CB-CD1 3.63Å; A53-Y256 HydrophobicContact CB-CE1 3.9Å; F193-Y256 AromaticContact CD1-CE1 3.96Å; F193-Y256 HydrophobicContact CD1-CE1 3.96Å; F193-Y256 HydrophobicContact CE1-CD1 4.23Å; F193-Y256 HydrophobicContact CE1-CE1 4.13Å; P194-Y256 VanDerWaalsContact CG-OH 3.3Å; P194-Y256 WeakPolarHBondContact CG-OH 3.14Å; N197-Y256 PolarHBondContact OD1-OH 3.16Å; L254-Y256 PolarHBondContact O-N 2.95Å; Y256-Y259 WeakPolarHBondContact O-CB 3.38Å; Y256-Y259 PolarHBondContact O-N 2.85Å; Y256-Y260 HydrophobicContact CD1-CD2 4.13Å; Y256-Y260 AromaticContact CD1-CE2 3.94Å; Y256-Y260 HydrophobicContact CD1-CE2 3.94Å; Y256-Y260 AromaticContact CD2-CE2 3.93Å; Y256-Y260 HydrophobicContact CD2-CE2 3.93Å; Y256-Y260 AromaticContact CE1-CD2 3.92Å; Y256-Y260 HydrophobicContact CE1-CD2 3.92Å; Y256-Y260 AromaticContact CE1-CE2 3.55Å; Y256-Y260 HydrophobicContact CE1-CE2 3.55Å; Y256-Y260 AromaticContact CE2-CE2 3.57Å; Y256-Y260 HydrophobicContact CE2-CE2 3.57Å; Y256-Y260 HydrophobicContact CG-CE2 4.12Å; Y256-Y260 AromaticContact CZ-CE2 3.37Å; Y256-Y260 WeakPolarHBondContact O-CD2 3.29Å; Y256-Y260 PolarHBondContact O-N 2.9Å
257	A	90.7	Very high	82.8	Confident	0 Å²	0	66.5 Å²	66.5	0%	0	35%	0.348	C	S	.	.	H	α-helix	trans	-69.7	-39.4	-177.7	0	0	0	0	0	112	F193 L251 L254 E255 Y259 Y260 M261	F193-A257 HydrophobicContact CE1-CB 4.03Å; F193-A257 HydrophobicContact CZ-CB 3.94Å; L251-A257 HydrophobicContact CD1-CB 3.83Å; L251-A257 HydrophobicContact CG-CB 4.02Å; L251-A257 WeakPolarHBondContact O-CB 3.48Å; L254-A257 HydrophobicContact CB-CB 4.08Å; L254-A257 PolarHBondContact O-N 3.46Å; L254-A257 VanDerWaalsContact O-N 3.09Å; E255-A257 PolarHBondContact O-N 3.38Å; A257-Y259 PolarHBondContact O-N 2.92Å; A257-Y260 PolarHBondContact O-N 3.31Å; A257-M261 HydrophobicContact CB-CE 3.84Å; A257-M261 WeakPolarHBondContact O-CB 3.44Å; A257-M261 WeakPolarHBondContact O-CG 3.42Å; A257-M261 PolarHBondContact O-N 3.32Å
258	R	89.7	Confident	80.1	Confident	139 Å²	139	73.2 Å²	73.2	53%	0.525	37%	0.371	S	S	.	.	H	α-helix	trans	-59.6	-34.5	174.7	-70.3	-170.9	-131	165	4.8	112.1	S252 Q253 L254 E255 R262	S252-R258 WeakPolarHBondContact O-CG 3.45Å; S252-R258 PolarHBondContact O-NE 3.27Å; Q253-R258 PolarHBondContact O-NE 3.08Å; Q253-R258 PolarHBondContact O-NH2 2.84Å; L254-R258 WeakPolarHBondContact O-CG 3.29Å; L254-R258 PolarHBondContact O-N 3.16Å; E255-R258 PolarHBondContact O-N 2.97Å; R258-R262 WeakPolarHBondContact O-CG 3.19Å; R258-R262 PolarHBondContact O-N 2.86Å
259	Y	89	Confident	77.8	Confident	56 Å²	56	75.7 Å²	75.7	22%	0.22	39%	0.386	C	S	.	.	H	α-helix	trans	-63.2	-45.5	176.4	177.1	-92.3	0	0	0	112.5	R45 P46 E255 Y256 A257 R443	R45-Y259 HydrophobicContact CG-CE1 4.17Å; P46-Y259 HydrophobicContact CG-CD1 4.31Å; P46-Y259 HydrophobicContact CG-CD2 4.16Å; P46-Y259 HydrophobicContact CG-CG 3.78Å; E255-Y259 PolarHBondContact O-N 3.14Å; Y256-Y259 WeakPolarHBondContact O-CB 3.38Å; Y256-Y259 PolarHBondContact O-N 2.85Å; A257-Y259 PolarHBondContact O-N 2.92Å; Y259-R443 PolarHBondContact O-NH2 3.39Å
260	Y	88	Confident	75.5	Confident	12 Å²	12	78 Å²	78	5%	0.047	39%	0.393	C	S	.	.	H	α-helix	trans	-77.3	-27.3	178.6	-62.6	-77.6	0	0	0	113.7	R45 S192 F193 P194 Y256 A257 R262 R443	R45-Y260 PolarHBondContact NE-OH 3.15Å; R45-Y260 PolarHBondContact NH2-OH 3.35Å; S192-Y260 WeakPolarHBondContact O-CD1 3.33Å; F193-Y260 AromaticContact CD1-CD2 3.77Å; F193-Y260 HydrophobicContact CD1-CD2 3.77Å; F193-Y260 HydrophobicContact CD1-CG 4.04Å; F193-Y260 AromaticContact CE1-CD2 3.88Å; F193-Y260 HydrophobicContact CE1-CD2 3.88Å; F193-Y260 HydrophobicContact CE1-CG 4.29Å; F193-Y260 HydrophobicContact CG-CD2 4.37Å; F193-Y260 HydrophobicContact CG-CG 4.2Å; P194-Y260 HydrophobicContact CG-CE1 4.08Å; P194-Y260 HydrophobicContact CG-CE2 4.46Å; Y256-Y260 HydrophobicContact CD1-CD2 4.13Å; Y256-Y260 AromaticContact CD1-CE2 3.94Å; Y256-Y260 HydrophobicContact CD1-CE2 3.94Å; Y256-Y260 AromaticContact CD2-CE2 3.93Å; Y256-Y260 HydrophobicContact CD2-CE2 3.93Å; Y256-Y260 AromaticContact CE1-CD2 3.92Å; Y256-Y260 HydrophobicContact CE1-CD2 3.92Å; Y256-Y260 AromaticContact CE1-CE2 3.55Å; Y256-Y260 HydrophobicContact CE1-CE2 3.55Å; Y256-Y260 AromaticContact CE2-CE2 3.57Å; Y256-Y260 HydrophobicContact CE2-CE2 3.57Å; Y256-Y260 HydrophobicContact CG-CE2 4.12Å; Y256-Y260 AromaticContact CZ-CE2 3.37Å; Y256-Y260 WeakPolarHBondContact O-CD2 3.29Å; Y256-Y260 PolarHBondContact O-N 2.9Å; A257-Y260 PolarHBondContact O-N 3.31Å; Y260-R262 VanDerWaalsContact C-N 3.32Å; Y260-R443 PolarHBondContact O-NH2 2.89Å
261	M	86	Confident	72.6	Confident	58 Å²	58	79.3 Å²	79.3	29%	0.286	41%	0.409	S	S	.	.	H	α-helix	trans	-80.3	-6.9	177.8	-72.4	-158.3	-103.2	0	0	114.5	L189 F193 L251 A257	L189-M261 HydrophobicContact CD1-CG 3.72Å; L189-M261 HydrophobicContact CD1-SD 3.76Å; L189-M261 HydrophobicContact CD2-SD 4.26Å; F193-M261 HydrophobicContact CE2-CG 3.92Å; F193-M261 HydrophobicContact CZ-CG 4.04Å; L251-M261 HydrophobicContact CG-CE 4.39Å; A257-M261 HydrophobicContact CB-CE 3.84Å; A257-M261 WeakPolarHBondContact O-CB 3.44Å; A257-M261 WeakPolarHBondContact O-CG 3.42Å; A257-M261 PolarHBondContact O-N 3.32Å
262	R	81	Confident	69.6	Low	160 Å²	160	82.5 Å²	82.5	60%	0.604	44%	0.442	S	S	*	.	S	Bend	trans	-60.7	133.5	176.4	-88.4	177.1	-174.9	-173.4	2.3	110.7	R258 Y260 V264	R258-R262 WeakPolarHBondContact O-CG 3.19Å; R258-R262 PolarHBondContact O-N 2.86Å; Y260-R262 VanDerWaalsContact C-N 3.32Å; R262-V264 PolarHBondContact O-N 3.32Å
263	P	69.8	Low	67	Low	130 Å²	130	89.2 Å²	89.2	84%	0.844	47%	0.47	S	S	*	.	P	Polyproline II helix	trans	-56.6	129.1	173.8	-21.4	31.1	0	0	0	110.5
264	V	63.8	Low	64.2	Low	63 Å²	63	91.2 Å²	91.2	38%	0.382	49%	0.485	S	S	.	.	P	Polyproline II helix	trans	-84.1	131	171.6	-177.7	0	0	0	0	107.4	R262 R443 E444	R262-V264 PolarHBondContact O-N 3.32Å; V264-R443 HydrophobicContact CG2-CG 4.1Å; V264-E444 HydrophobicContact CB-CG 4.04Å; V264-E444 HydrophobicContact CG1-CG 3.92Å
265	A	52.2	Low	61.3	Low	75 Å²	75	96 Å²	96	62%	0.62	51%	0.51	S	S	*	.	P	Polyproline II helix	trans	-61	135.5	175.9	0	0	0	0	0	109.3	V267 E444	A265-V267 PolarHBondContact O-N 3.07Å; A265-E444 VanDerWaalsContact O-OE1 3.12Å
266	P	50.3	Low	58.5	Low	104 Å²	104	95.3 Å²	95.3	68%	0.675	52%	0.517	S	S	*	.			trans	-66.7	106.5	-173.6	25	-32.3	0	0	0	110.7	E444	P266-E444 WeakPolarHBondContact CA-OE2 3.48Å
267	V	45.9	Very low	55.7	Low	71 Å²	71	100.3 Å²	100.3	43%	0.43	55%	0.553	S	S	.	*			trans	-85.6	130.1	170.6	-178.8	0	0	0	0	107.6	L36 A265 V269 E444	L36-V267 HydrophobicContact CD2-CG2 4.43Å; A265-V267 PolarHBondContact O-N 3.07Å; V267-V269 VanDerWaalsContact C-N 3.35Å; V267-V269 HydrophobicContact CB-CG2 4.14Å; V267-V269 HydrophobicContact CG1-CG2 3.98Å; V267-V269 WeakPolarHBondContact O-CG2 3.21Å; V267-V269 PolarHBondContact O-N 3.48Å; V267-E444 PolarHBondContact N-OE1 3.33Å; V267-E444 PolarHBondContact N-OE2 3.34Å
268	R	41.9	Very low	53	Low	172 Å²	172	108.4 Å²	108.4	65%	0.649	59%	0.591	S	S	*	*			trans	-67.5	90.8	174.7	-71.8	-175	-178.7	170.8	1.2	109.6
269	V	47.9	Very low	50.3	Low	53 Å²	53	109.5 Å²	109.5	32%	0.321	61%	0.607	S	S	.	*			trans	-94.1	-11.2	-179.2	-175.8	0	0	0	0	113.3	V267 P442	V267-V269 VanDerWaalsContact C-N 3.35Å; V267-V269 HydrophobicContact CB-CG2 4.14Å; V267-V269 HydrophobicContact CG1-CG2 3.98Å; V267-V269 WeakPolarHBondContact O-CG2 3.21Å; V267-V269 PolarHBondContact O-N 3.48Å; V269-P442 HydrophobicContact CB-CG 4.34Å; V269-P442 HydrophobicContact CG1-CG 3.77Å; V269-P442 HydrophobicContact CG2-CG 4.45Å
270	F	47.5	Very low	47.7	Very low	121 Å²	121	111.5 Å²	111.5	53%	0.531	64%	0.635	S	S	.	*	S	Bend	trans	-119.1	20.5	-174.6	-68.8	-78.1	0	0	0	116.1	P300 L445	F270-P300 HydrophobicContact CD1-CB 4.29Å; F270-P300 HydrophobicContact CE1-CB 3.95Å; F270-P300 HydrophobicContact CZ-CB 4.26Å; F270-L445 HydrophobicContact CD2-CD1 4.45Å; F270-L445 HydrophobicContact CE2-CD1 3.47Å; F270-L445 VanDerWaalsContact CE2-CD1 3.47Å; F270-L445 HydrophobicContact CZ-CD1 3.99Å
271	S	33.3	Very low	45.2	Very low	108 Å²	108	116.6 Å²	116.6	76%	0.755	67%	0.67	S	S	*	*			trans	-101.1	46.4	174	-66.3	0	0	0	0	112.8
272	G	32.5	Very low	42.6	Very low	67 Å²	67	119.4 Å²	119.4	69%	0.691	70%	0.695	S	S	*	*			trans	-140.1	54.4	-175.9	0	0	0	0	0	113.3
273	E	34.3	Very low	40.2	Very low	174 Å²	174	116.1 Å²	116.1	81%	0.813	70%	0.702	S	S	*	*	S	Bend	trans	-152.3	11.3	163.5	-116.1	171.9	124.6	0	0	114.1
274	D	31.5	Very low	38.3	Very low	166 Å²	166	115.5 Å²	115.5	89%	0.888	70%	0.701	S	S	*	*	S	Bend	trans	-106.7	116.9	169.3	-72.4	-34.5	0	0	0	109.4
275	N	30.2	Very low	36.7	Very low	148 Å²	148	117.8 Å²	117.8	79%	0.791	72%	0.72	S	S	*	*			trans	-34.9	139.5	-176.9	-71.6	-50.5	0	0	0	115.5	S277	N275-S277 VanDerWaalsContact C-N 3.3Å; N275-S277 PolarHBondContact O-N 2.86Å
276	P	32.4	Very low	35.7	Very low	117 Å²	117	120.3 Å²	120.3	76%	0.76	73%	0.727	S	S	*	*			trans	-74.5	90.2	159.8	31.5	-27.7	0	0	0	107.9	Q278	P276-Q278 VanDerWaalsContact C-N 3.27Å; P276-Q278 PolarHBondContact O-N 2.82Å
277	S	33	Very low	34.9	Very low	112 Å²	112	119.1 Å²	119.1	78%	0.783	73%	0.726	S	S	*	*			trans	-65.4	98.4	154.7	51.7	0	0	0	0	107.1	N275 D279	N275-S277 VanDerWaalsContact C-N 3.3Å; N275-S277 PolarHBondContact O-N 2.86Å; S277-D279 PolarHBondContact O-N 2.99Å; S277-D279 VanDerWaalsContact O-N 3.15Å
278	Q	33.4	Very low	34.3	Very low	170 Å²	170	119.5 Å²	119.5	79%	0.794	73%	0.73	S	S	*	*			trans	-56.6	109.4	157.8	-67.6	177.9	6.3	0	0	106.5	P276	P276-Q278 VanDerWaalsContact C-N 3.27Å; P276-Q278 PolarHBondContact O-N 2.82Å
279	D	33.3	Very low	33.9	Very low	163 Å²	163	115.7 Å²	115.7	87%	0.872	74%	0.735	S	S	*	*			trans	161.5	85.9	148.9	-80.4	-20	0	0	0	110.4	S277	S277-D279 PolarHBondContact O-N 2.99Å; S277-D279 VanDerWaalsContact O-N 3.15Å
280	A	33.9	Very low	33.5	Very low	97 Å²	97	117.4 Å²	117.4	80%	0.802	75%	0.75	S	S	*	*			trans	-166.9	117.4	150.7	0	0	0	0	0	110.4
281	P	35.5	Very low	33.3	Very low	119 Å²	119	123.4 Å²	123.4	77%	0.773	77%	0.769	S	S	*	*			trans	-87.3	133.9	170.7	32.1	-26.8	0	0	0	111
282	S	31.2	Very low	34.3	Very low	118 Å²	118	123.5 Å²	123.5	83%	0.825	76%	0.764	S	S	*	*			trans	55.7	92.6	153.1	57.3	0	0	0	0	118.9
283	A	31	Very low	35.7	Very low	91 Å²	91	125.2 Å²	125.2	75%	0.752	76%	0.756	S	S	*	*			trans	-149	112.6	141.6	0	0	0	0	0	109.7	S285	A283-S285 PolarHBondContact O-N 3.14Å; A283-S285 VanDerWaalsContact O-N 3.12Å
284	S	28.9	Very low	37.6	Very low	117 Å²	117	121.8 Å²	121.8	82%	0.818	74%	0.739	S	S	*	*			trans	11	86.1	159.2	54.6	0	0	0	0	116.5	V286	S284-V286 PolarHBondContact O-N 3.05Å
285	S	30.7	Very low	39.9	Very low	110 Å²	110	116.6 Å²	116.6	77%	0.769	71%	0.714	S	S	*	*			trans	-80.6	89.2	169.5	-157.8	0	0	0	0	108.8	A283 A287	A283-S285 PolarHBondContact O-N 3.14Å; A283-S285 VanDerWaalsContact O-N 3.12Å; S285-A287 PolarHBondContact O-N 3.16Å; S285-A287 VanDerWaalsContact O-N 3.14Å
286	V	32.1	Very low	42.5	Very low	129 Å²	129	109.8 Å²	109.8	78%	0.782	68%	0.678	S	S	*	*			trans	-51.5	116.4	152.9	175.1	0	0	0	0	105.6	S284	S284-V286 PolarHBondContact O-N 3.05Å
287	A	31.9	Very low	45.3	Very low	78 Å²	78	105.4 Å²	105.4	65%	0.645	65%	0.649	S	S	*	*			trans	-42.7	128.2	177.4	0	0	0	0	0	108.9	S285 A289	S285-A287 PolarHBondContact O-N 3.16Å; S285-A287 VanDerWaalsContact O-N 3.14Å; A287-A289 PolarHBondContact O-N 3.37Å
288	P	33.2	Very low	48.2	Very low	80 Å²	80	103.8 Å²	103.8	52%	0.519	63%	0.631	S	S	.	*			trans	-62.2	111.3	178.9	-11.1	23	0	0	0	106	S290	P288-S290 PolarHBondContact O-N 3.23Å
289	A	34.6	Very low	51	Low	92 Å²	92	98 Å²	98	76%	0.76	62%	0.618	S	S	*	*			trans	-43.4	117.8	169.6	0	0	0	0	0	106.3	A287 R291	A287-A289 PolarHBondContact O-N 3.37Å; A289-R291 PolarHBondContact O-N 3.42Å
290	S	38.5	Very low	53.9	Low	89 Å²	89	92.8 Å²	92.8	62%	0.622	59%	0.593	S	S	*	*			trans	-47.9	104.3	-178.9	49.4	0	0	0	0	108	P288 V292	P288-S290 PolarHBondContact O-N 3.23Å; S290-V292 PolarHBondContact O-N 3.41Å
291	R	43	Very low	56.8	Low	247 Å²	247	88.2 Å²	88.2	93%	0.932	56%	0.555	S	S	*	*			trans	-65.2	95.6	172.4	-89.7	-176.2	175.2	173.3	-0.8	105.4	A289 M293	A289-R291 PolarHBondContact O-N 3.42Å; R291-M293 PolarHBondContact O-N 3.49Å
292	V	55.5	Low	59.6	Low	109 Å²	109	85.4 Å²	85.4	66%	0.661	53%	0.533	S	S	*	.			trans	-56.8	105.9	171.8	177.3	0	0	0	0	105.6	S290 H294	S290-V292 PolarHBondContact O-N 3.41Å; V292-H294 PolarHBondContact O-N 3.13Å
293	M	61.2	Low	62.7	Low	104 Å²	104	87.6 Å²	87.6	51%	0.512	53%	0.528	S	S	.	.			trans	-71.1	106.4	-173.7	-149.7	177	155.1	0	0	107.6	N127 R291 T295 P297	N127-M293 PolarHBondContact ND2-O 3.42Å; R291-M293 PolarHBondContact O-N 3.49Å; M293-T295 WeakPolarHBondContact CG-O 3.31Å; M293-T295 PolarHBondContact O-N 3.49Å; M293-P297 HydrophobicContact CE-CB 3.71Å; M293-P297 HydrophobicContact CE-CG 4.48Å; M293-P297 HydrophobicContact SD-CB 4.1Å; M293-P297 HydrophobicContact SD-CG 4.33Å
294	H	73.9	Confident	65.7	Low	101 Å²	101	88.1 Å²	88.1	47%	0.468	51%	0.513	S	S	.	.	S	Bend	trans	-65.7	-17.4	-173.5	-85.7	-43.4	0	0	0	114.6	R128 V292	R128-H294 VanDerWaalsContact CZ-CB 3.4Å; R128-H294 VanDerWaalsContact CZ-ND1 3.31Å; R128-H294 PolarHBondContact NE-O 3.17Å; R128-H294 PolarHBondContact NH1-ND1 2.9Å; R128-H294 VanDerWaalsContact NH2-CB 3.25Å; R128-H294 VanDerWaalsContact NH2-CG 3.3Å; V292-H294 PolarHBondContact O-N 3.13Å
295	T	80.6	Confident	68.9	Low	58 Å²	58	82.5 Å²	82.5	36%	0.356	47%	0.474	S	S	.	.	S	Bend	trans	-132.4	145.6	173.8	48.4	0	0	0	0	108.8	L124 M293	L124-T295 HydrophobicContact CD2-CG2 4.28Å; M293-T295 WeakPolarHBondContact CG-O 3.31Å; M293-T295 PolarHBondContact O-N 3.49Å
296	P	85.5	Confident	72	Confident	4 Å²	4	79.8 Å²	79.8	3%	0.026	46%	0.458	C	S	.	.			trans	-62.3	142.2	175.1	-17.7	29.1	0	0	0	111.1	F123 V126 L298 I301 A448	F123-P296 HydrophobicContact CE2-CB 4.08Å; F123-P296 HydrophobicContact CE2-CG 4.22Å; F123-P296 HydrophobicContact CZ-CB 3.81Å; F123-P296 HydrophobicContact CZ-CG 4.11Å; V126-P296 HydrophobicContact CB-CG 4.19Å; V126-P296 HydrophobicContact CG1-CG 4.34Å; P296-L298 PolarHBondContact O-N 2.65Å; P296-I301 HydrophobicContact CB-CD1 4.15Å; P296-A448 HydrophobicContact CB-CB 3.42Å; P296-A448 VanDerWaalsContact CB-CB 3.42Å; P296-A448 HydrophobicContact CG-CB 3.51Å
297	P	91	Very high	75	Confident	25 Å²	25	76.9 Å²	76.9	16%	0.162	44%	0.444	C	S	.	.			trans	-68	94.2	178	27.9	-34.8	0	0	0	111.1	M293 G299 P300 I301 L445	M293-P297 HydrophobicContact CE-CB 3.71Å; M293-P297 HydrophobicContact CE-CG 4.48Å; M293-P297 HydrophobicContact SD-CB 4.1Å; M293-P297 HydrophobicContact SD-CG 4.33Å; P297-G299 PolarHBondContact O-N 2.84Å; P297-P300 HydrophobicContact CB-CG 4.14Å; P297-P300 WeakPolarHBondContact O-CD 3.41Å; P297-I301 WeakPolarHBondContact O-CD1 3.46Å; P297-I301 VanDerWaalsContact O-CG1 3.28Å; P297-I301 WeakPolarHBondContact O-CG1 3.41Å; P297-I301 PolarHBondContact O-N 3.18Å; P297-L445 HydrophobicContact CG-CD1 4.11Å; P297-L445 HydrophobicContact CG-CD2 3.84Å
298	L	92.5	Very high	78.1	Confident	78 Å²	78	73.4 Å²	73.4	41%	0.408	41%	0.414	S	S	.	.	H	α-helix	trans	-62.2	-45.9	-175	-178.1	63.7	0	0	0	113	F123 P296 I301 L302 V452	F123-L298 HydrophobicContact CE1-CB 4.19Å; F123-L298 HydrophobicContact CE1-CD1 4.05Å; F123-L298 HydrophobicContact CE2-CD1 4.17Å; F123-L298 HydrophobicContact CZ-CB 3.99Å; F123-L298 HydrophobicContact CZ-CD1 3.66Å; F123-L298 HydrophobicContact CZ-CG 4.37Å; P296-L298 PolarHBondContact O-N 2.65Å; L298-I301 PolarHBondContact O-N 3.22Å; L298-L302 HydrophobicContact CD1-CD1 3.96Å; L298-L302 HydrophobicContact CD1-CD2 4.1Å; L298-L302 HydrophobicContact CD1-CG 3.82Å; L298-L302 HydrophobicContact CD2-CD1 4.21Å; L298-L302 HydrophobicContact CG-CD1 3.7Å; L298-L302 HydrophobicContact CG-CG 4.01Å; L298-L302 WeakPolarHBondContact O-CG 3.39Å; L298-L302 PolarHBondContact O-N 3.2Å; L298-V452 HydrophobicContact CD1-CG2 4.07Å
299	G	93.1	Very high	81.1	Confident	50 Å²	50	69.7 Å²	69.7	52%	0.515	39%	0.39	S	S	.	.	H	α-helix	trans	-55.6	-54.4	-176.4	0	0	0	0	0	113.8	P297 I301 L302 K303	P297-G299 PolarHBondContact O-N 2.84Å; G299-I301 VanDerWaalsContact C-N 3.34Å; G299-I301 PolarHBondContact O-N 3.33Å; G299-L302 PolarHBondContact O-N 2.98Å; G299-K303 PolarHBondContact O-N 2.92Å
300	P	93.1	Very high	84.1	Confident	52 Å²	52	70.6 Å²	70.6	34%	0.338	38%	0.377	S	S	.	.	H	α-helix	trans	-58.8	-40.4	175.1	-28.1	36.2	0	0	0	113.9	F270 P297 K303 K304	F270-P300 HydrophobicContact CD1-CB 4.29Å; F270-P300 HydrophobicContact CE1-CB 3.95Å; F270-P300 HydrophobicContact CZ-CB 4.26Å; P297-P300 HydrophobicContact CB-CG 4.14Å; P297-P300 WeakPolarHBondContact O-CD 3.41Å; P300-K303 PolarHBondContact O-N 2.66Å; P300-K304 PolarHBondContact O-N 3.1Å
301	I	94.8	Very high	87	Confident	1 Å²	1	66.3 Å²	66.3	1%	0.005	35%	0.347	C	S	.	.	H	α-helix	trans	-61.6	-48.8	177.1	-67.2	168.4	0	0	0	110.1	P296 P297 L298 G299 K303 K304 T305 L445 A448 T449 V452	P296-I301 HydrophobicContact CB-CD1 4.15Å; P297-I301 WeakPolarHBondContact O-CD1 3.46Å; P297-I301 VanDerWaalsContact O-CG1 3.28Å; P297-I301 WeakPolarHBondContact O-CG1 3.41Å; P297-I301 PolarHBondContact O-N 3.18Å; L298-I301 PolarHBondContact O-N 3.22Å; G299-I301 VanDerWaalsContact C-N 3.34Å; G299-I301 PolarHBondContact O-N 3.33Å; I301-K303 PolarHBondContact O-N 2.91Å; I301-K304 PolarHBondContact O-N 3.17Å; I301-T305 HydrophobicContact CG2-CG2 4.48Å; I301-T305 WeakPolarHBondContact O-CB 3.2Å; I301-T305 WeakPolarHBondContact O-CG2 3.39Å; I301-T305 PolarHBondContact O-N 2.67Å; I301-T305 PolarHBondContact O-OG1 2.89Å; I301-L445 HydrophobicContact CG1-CD1 4.21Å; I301-A448 HydrophobicContact CD1-CB 4.02Å; I301-T449 HydrophobicContact CG2-CG2 4.15Å; I301-V452 HydrophobicContact CG2-CB 4.17Å; I301-V452 HydrophobicContact CG2-CG1 4.25Å; I301-V452 HydrophobicContact CG2-CG2 3.96Å
302	L	95.8	Very high	89.6	Confident	61 Å²	61	54.6 Å²	54.6	32%	0.319	30%	0.303	S	S	.	.	H	α-helix	trans	-61.2	-43.8	177.6	-66.4	176.8	0	0	0	111.8	L298 G299 K304 T305 A306 V452 Y456	L298-L302 HydrophobicContact CD1-CD1 3.96Å; L298-L302 HydrophobicContact CD1-CD2 4.1Å; L298-L302 HydrophobicContact CD1-CG 3.82Å; L298-L302 HydrophobicContact CD2-CD1 4.21Å; L298-L302 HydrophobicContact CG-CD1 3.7Å; L298-L302 HydrophobicContact CG-CG 4.01Å; L298-L302 WeakPolarHBondContact O-CG 3.39Å; L298-L302 PolarHBondContact O-N 3.2Å; G299-L302 PolarHBondContact O-N 2.98Å; L302-K304 PolarHBondContact O-N 3.05Å; L302-T305 PolarHBondContact O-N 3.37Å; L302-A306 WeakPolarHBondContact O-CA 3.41Å; L302-A306 WeakPolarHBondContact O-CB 3.45Å; L302-A306 PolarHBondContact O-N 3.06Å; L302-V452 HydrophobicContact CD2-CG1 3.8Å; L302-Y456 HydrophobicContact CD2-CE1 4.45Å; L302-Y456 WeakPolarHBondContact CD2-OH 3.46Å
303	K	95.1	Very high	91.6	Very high	163 Å²	163	51 Å²	51	71%	0.709	28%	0.281	S	S	*	.	H	α-helix	trans	-59.7	-45	177.3	-173.8	-179.2	178.5	-174.6	0	111.5	G299 P300 I301	G299-K303 PolarHBondContact O-N 2.92Å; P300-K303 PolarHBondContact O-N 2.66Å; I301-K303 PolarHBondContact O-N 2.91Å
304	K	94.8	Very high	93.3	Very high	102 Å²	102	46.5 Å²	46.5	44%	0.443	26%	0.26	S	S	.	.	H	α-helix	trans	-71.8	-36.4	-179.1	-161.1	72.3	173.2	-168.3	0	111.9	P300 I301 L302 I440 V441	P300-K304 PolarHBondContact O-N 3.1Å; I301-K304 PolarHBondContact O-N 3.17Å; L302-K304 PolarHBondContact O-N 3.05Å; K304-I440 VanDerWaalsContact CE-O 3.27Å; K304-I440 WeakPolarHBondContact CE-O 3.29Å; K304-I440 HydrophobicContact CG-CD1 4.2Å; K304-I440 HydrophobicContact CG-CG1 4.44Å; K304-I440 VanDerWaalsContact O-CD1 3.23Å; K304-I440 WeakPolarHBondContact O-CD1 3.29Å; K304-V441 HydrophobicContact CB-CG1 4.35Å; K304-V441 HydrophobicContact CG-CG1 4.17Å
305	T	95.7	Very high	94.5	Very high	0 Å²	0	41.7 Å²	41.7	0%	0	24%	0.238	C	C	.	.	H	α-helix	trans	-89.8	-6.7	-177.4	54.6	0	0	0	0	115	I301 L302 S307 L308 G309 I440 T449 M453	I301-T305 HydrophobicContact CG2-CG2 4.48Å; I301-T305 WeakPolarHBondContact O-CB 3.2Å; I301-T305 WeakPolarHBondContact O-CG2 3.39Å; I301-T305 PolarHBondContact O-N 2.67Å; I301-T305 PolarHBondContact O-OG1 2.89Å; L302-T305 PolarHBondContact O-N 3.37Å; T305-S307 VanDerWaalsContact C-N 3.3Å; T305-S307 PolarHBondContact O-N 2.85Å; T305-L308 CarbonylContact O-C 3.58Å; T305-L308 WeakPolarHBondContact O-CA 3.3Å; T305-L308 PolarHBondContact O-N 3.39Å; T305-G309 PolarHBondContact O-N 3.25Å; T305-I440 HydrophobicContact CG2-CD1 4.22Å; T305-T449 HydrophobicContact CG2-CG2 3.53Å; T305-M453 HydrophobicContact CG2-SD 4.22Å
306	A	95.5	Very high	95.3	Very high	53 Å²	53	39.7 Å²	39.7	44%	0.438	22%	0.224	S	C	.	.	H	α-helix	trans	-47.2	-45.9	-172	0	0	0	0	0	114.6	L302 G309 F310	L302-A306 WeakPolarHBondContact O-CA 3.41Å; L302-A306 WeakPolarHBondContact O-CB 3.45Å; L302-A306 PolarHBondContact O-N 3.06Å; A306-G309 PolarHBondContact O-N 3.34Å; A306-F310 PolarHBondContact O-N 3.38Å
307	S	95.6	Very high	95.9	Very high	68 Å²	68	41.5 Å²	41.5	48%	0.476	23%	0.231	S	C	.	.	H	α-helix	trans	-66.2	-40.1	179.1	-174	0	0	0	0	112.8	T305 C311	T305-S307 VanDerWaalsContact C-N 3.3Å; T305-S307 PolarHBondContact O-N 2.85Å; S307-C311 PolarHBondContact O-N 2.86Å; S307-C311 PolarHBondContact O-SG 3.25Å
308	L	97	Very high	96.2	Very high	5 Å²	5	40.3 Å²	40.3	3%	0.026	22%	0.223	C	C	.	.	H	α-helix	trans	-73.4	-35.3	176.6	-68.8	179.4	0	0	0	110.9	T305 C311 A312 L379 V433 I440 M453	T305-L308 CarbonylContact O-C 3.58Å; T305-L308 WeakPolarHBondContact O-CA 3.3Å; T305-L308 PolarHBondContact O-N 3.39Å; L308-C311 WeakPolarHBondContact O-CB 3.47Å; L308-C311 PolarHBondContact O-N 2.81Å; L308-A312 PolarHBondContact O-N 3.23Å; L308-L379 HydrophobicContact CD2-CD2 3.84Å; L308-V433 HydrophobicContact CB-CG1 4.22Å; L308-V433 WeakPolarHBondContact O-CG1 3.36Å; L308-I440 HydrophobicContact CD1-CD1 3.7Å; L308-I440 HydrophobicContact CD1-CG1 4.26Å; L308-I440 HydrophobicContact CG-CD1 4.49Å; L308-M453 HydrophobicContact CB-CE 3.92Å; L308-M453 HydrophobicContact CB-SD 4.38Å
309	G	97.2	Very high	96.4	Very high	1 Å²	1	37.1 Å²	37.1	1%	0.01	21%	0.207	C	C	.	.	H	α-helix	trans	-61.3	-45.6	172.9	0	0	0	0	0	112.2	T305 A306 C311 A312 V313 Y456	T305-G309 PolarHBondContact O-N 3.25Å; A306-G309 PolarHBondContact O-N 3.34Å; G309-C311 VanDerWaalsContact C-N 3.29Å; G309-C311 PolarHBondContact O-N 3.06Å; G309-A312 PolarHBondContact O-N 2.86Å; G309-V313 WeakPolarHBondContact O-CG2 3.49Å; G309-V313 PolarHBondContact O-N 2.96Å; G309-Y456 VanDerWaalsContact CA-CE2 3.49Å
310	F	97.3	Very high	96.5	Very high	111 Å²	111	35 Å²	35	49%	0.487	19%	0.185	S	C	.	.	H	α-helix	trans	-57.4	-43	172.1	174.2	-99	0	0	0	111.9	A306 S314 V384	A306-F310 PolarHBondContact O-N 3.38Å; F310-S314 VanDerWaalsContact O-CB 3.27Å; F310-S314 WeakPolarHBondContact O-CB 3.42Å; F310-S314 PolarHBondContact O-N 2.78Å; F310-S314 PolarHBondContact O-OG 2.95Å; F310-V384 HydrophobicContact CE1-CG2 4Å; F310-V384 HydrophobicContact CZ-CG2 4.23Å
311	C	98	Very high	96.6	Very high	0 Å²	0	33.7 Å²	33.7	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-62.8	-46.7	176.1	-67.2	0	0	0	0	111.6	S307 L308 G309 S314 L315 V383 V433	S307-C311 PolarHBondContact O-N 2.86Å; S307-C311 PolarHBondContact O-SG 3.25Å; L308-C311 WeakPolarHBondContact O-CB 3.47Å; L308-C311 PolarHBondContact O-N 2.81Å; G309-C311 VanDerWaalsContact C-N 3.29Å; G309-C311 PolarHBondContact O-N 3.06Å; C311-S314 PolarHBondContact O-N 3.13Å; C311-L315 WeakPolarHBondContact O-CB 3.46Å; C311-L315 WeakPolarHBondContact O-CD1 3.5Å; C311-L315 WeakPolarHBondContact O-CG 3.45Å; C311-L315 PolarHBondContact O-N 2.87Å; C311-V383 HydrophobicContact CB-CG2 4Å; C311-V433 HydrophobicContact CB-CG1 4.33Å; C311-V433 HydrophobicContact CB-CG2 3.65Å
312	A	97.7	Very high	96.6	Very high	1 Å²	1	33.6 Å²	33.6	1%	0.008	17%	0.174	C	C	.	.	H	α-helix	trans	-60	-52.7	178.2	0	0	0	0	0	111.2	L308 G309 S314 L315 Y316 V433 M453	L308-A312 PolarHBondContact O-N 3.23Å; G309-A312 PolarHBondContact O-N 2.86Å; A312-S314 VanDerWaalsContact C-N 3.32Å; A312-S314 PolarHBondContact O-N 3.21Å; A312-L315 PolarHBondContact O-N 3.02Å; A312-Y316 VanDerWaalsContact O-CD2 3.27Å; A312-Y316 WeakPolarHBondContact O-CD2 3.38Å; A312-Y316 PolarHBondContact O-N 3.43Å; A312-V433 HydrophobicContact CB-CG1 3.77Å; A312-M453 HydrophobicContact CB-CE 4.32Å
313	V	98.2	Very high	96.5	Very high	33 Å²	33	31.8 Å²	31.8	20%	0.2	16%	0.164	C	C	.	.	H	α-helix	trans	-56.1	-48.4	178.9	172.9	0	0	0	0	110.3	G309 L315 Y316 F317 Y456 V459 G460	G309-V313 WeakPolarHBondContact O-CG2 3.49Å; G309-V313 PolarHBondContact O-N 2.96Å; V313-L315 PolarHBondContact O-N 3.08Å; V313-Y316 PolarHBondContact O-N 2.89Å; V313-F317 WeakPolarHBondContact O-CB 3.37Å; V313-F317 PolarHBondContact O-N 2.92Å; V313-Y456 HydrophobicContact CG2-CD1 4.12Å; V313-Y456 WeakPolarHBondContact CG2-O 3.44Å; V313-V459 HydrophobicContact CG1-CG1 4.49Å; V313-V459 HydrophobicContact CG2-CB 4.43Å; V313-V459 HydrophobicContact CG2-CG1 4.32Å; V313-G460 WeakPolarHBondContact O-CA 3.47Å
314	S	98	Very high	96.2	Very high	9 Å²	9	27.2 Å²	27.2	6%	0.063	15%	0.151	C	C	.	.	H	α-helix	trans	-64.4	-41.7	-178.8	-59.9	0	0	0	0	112.9	F310 C311 A312 V318 V383	F310-S314 VanDerWaalsContact O-CB 3.27Å; F310-S314 WeakPolarHBondContact O-CB 3.42Å; F310-S314 PolarHBondContact O-N 2.78Å; F310-S314 PolarHBondContact O-OG 2.95Å; C311-S314 PolarHBondContact O-N 3.13Å; A312-S314 VanDerWaalsContact C-N 3.32Å; A312-S314 PolarHBondContact O-N 3.21Å; S314-V318 WeakPolarHBondContact O-CG2 3.49Å; S314-V318 PolarHBondContact O-N 3.41Å; S314-V318 VanDerWaalsContact O-N 3.08Å; S314-V383 VanDerWaalsContact CB-CG1 3.49Å
315	L	98	Very high	95.7	Very high	0 Å²	0	23 Å²	23	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-60.7	-50.9	178	-78.7	167.1	0	0	0	111.7	C311 A312 V313 T319 V383 L429 V433	C311-L315 WeakPolarHBondContact O-CB 3.46Å; C311-L315 WeakPolarHBondContact O-CD1 3.5Å; C311-L315 WeakPolarHBondContact O-CG 3.45Å; C311-L315 PolarHBondContact O-N 2.87Å; A312-L315 PolarHBondContact O-N 3.02Å; V313-L315 PolarHBondContact O-N 3.08Å; L315-T319 PolarHBondContact O-N 3.29Å; L315-T319 PolarHBondContact O-OG1 3.47Å; L315-T319 VanDerWaalsContact O-OG1 3.1Å; L315-V383 HydrophobicContact CD1-CG2 3.91Å; L315-V383 HydrophobicContact CD2-CB 4.39Å; L315-V383 HydrophobicContact CD2-CG1 4.13Å; L315-V383 HydrophobicContact CD2-CG2 3.89Å; L315-V383 HydrophobicContact CG-CB 4.31Å; L315-V383 HydrophobicContact CG-CG1 3.74Å; L315-V383 HydrophobicContact CG-CG2 3.75Å; L315-L429 HydrophobicContact CD1-CB 3.92Å; L315-L429 HydrophobicContact CD2-CB 3.66Å; L315-L429 HydrophobicContact CD2-CD1 4.01Å; L315-L429 HydrophobicContact CD2-CG 4.5Å; L315-L429 HydrophobicContact CG-CB 4.45Å; L315-V433 HydrophobicContact CD1-CG2 3.93Å
316	Y	97.3	Very high	95.5	Very high	17 Å²	17	23.1 Å²	23.1	7%	0.067	14%	0.136	C	C	.	.	H	α-helix	trans	-75.9	-28.7	-177.3	-75.2	-77.9	0	0	0	112.2	A312 V313 A320 M457 L461	A312-Y316 VanDerWaalsContact O-CD2 3.27Å; A312-Y316 WeakPolarHBondContact O-CD2 3.38Å; A312-Y316 PolarHBondContact O-N 3.43Å; V313-Y316 PolarHBondContact O-N 2.89Å; Y316-A320 VanDerWaalsContact O-CB 3.23Å; Y316-A320 WeakPolarHBondContact O-CB 3.32Å; Y316-A320 PolarHBondContact O-N 3.25Å; Y316-M457 HydrophobicContact CD1-CG 3.82Å; Y316-M457 HydrophobicContact CD2-CB 3.83Å; Y316-M457 HydrophobicContact CD2-CG 3.58Å; Y316-M457 HydrophobicContact CE1-CG 3.69Å; Y316-M457 HydrophobicContact CE1-SD 3.86Å; Y316-M457 HydrophobicContact CE2-CB 3.81Å; Y316-M457 HydrophobicContact CE2-CG 3.47Å; Y316-M457 VanDerWaalsContact CE2-CG 3.47Å; Y316-M457 HydrophobicContact CE2-SD 4.03Å; Y316-M457 HydrophobicContact CG-CB 4.4Å; Y316-M457 HydrophobicContact CG-CG 3.76Å; Y316-M457 VanDerWaalsContact CZ-SD 3.56Å; Y316-L461 HydrophobicContact CD1-CD2 3.82Å; Y316-L461 HydrophobicContact CD1-CG 4.04Å; Y316-L461 HydrophobicContact CG-CD2 4.45Å; Y316-L461 HydrophobicContact CG-CG 4.37Å
317	F	97.6	Very high	95.3	Very high	41 Å²	41	20.7 Å²	20.7	18%	0.18	12%	0.115	C	C	.	.	H	α-helix	trans	-58.7	-55.8	169.5	178.2	-84.9	0	0	0	111.1	V313 T319 A320 F321 F387 G460 L463 C467	V313-F317 WeakPolarHBondContact O-CB 3.37Å; V313-F317 PolarHBondContact O-N 2.92Å; F317-T319 VanDerWaalsContact C-N 3.31Å; F317-T319 PolarHBondContact O-N 3.36Å; F317-A320 PolarHBondContact O-N 3.01Å; F317-F321 HydrophobicContact CE1-CB 4.4Å; F317-F321 HydrophobicContact CE1-CD2 4.28Å; F317-F321 HydrophobicContact CE1-CG 4.45Å; F317-F321 HydrophobicContact CZ-CD2 4.11Å; F317-F321 WeakPolarHBondContact O-CB 3.3Å; F317-F321 PolarHBondContact O-N 2.94Å; F317-F387 AromaticContact CD1-CE1 3.81Å; F317-F387 HydrophobicContact CD1-CE1 3.81Å; F317-F387 AromaticContact CD1-CZ 3.91Å; F317-F387 HydrophobicContact CD1-CZ 3.91Å; F317-F387 AromaticContact CE1-CE1 3.8Å; F317-F387 HydrophobicContact CE1-CE1 3.8Å; F317-F387 HydrophobicContact CE1-CZ 4.32Å; F317-G460 VanDerWaalsContact CA-O 3.24Å; F317-G460 WeakPolarHBondContact CA-O 3.41Å; F317-G460 PolarHBondContact N-O 3.4Å; F317-L463 HydrophobicContact CD2-CB 3.72Å; F317-L463 HydrophobicContact CE2-CB 4.07Å; F317-C467 HydrophobicContact CE2-CB 4.16Å; F317-C467 HydrophobicContact CZ-CB 4.09Å
318	V	97.7	Very high	95.1	Very high	0 Å²	0	19.5 Å²	19.5	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-60.8	-42.5	-178	172.5	0	0	0	0	111	S314 F321 I322 R386 F387 V390 L422	S314-V318 WeakPolarHBondContact O-CG2 3.49Å; S314-V318 PolarHBondContact O-N 3.41Å; S314-V318 VanDerWaalsContact O-N 3.08Å; V318-F321 PolarHBondContact O-N 3.19Å; V318-I322 HydrophobicContact CG1-CD1 3.9Å; V318-I322 WeakPolarHBondContact O-CG1 3.28Å; V318-I322 PolarHBondContact O-N 2.9Å; V318-R386 HydrophobicContact CG1-CB 4.17Å; V318-R386 WeakPolarHBondContact CG1-O 3.47Å; V318-F387 HydrophobicContact CG2-CD1 3.88Å; V318-F387 HydrophobicContact CG2-CD2 3.63Å; V318-F387 HydrophobicContact CG2-CE1 3.86Å; V318-F387 HydrophobicContact CG2-CE2 3.61Å; V318-F387 HydrophobicContact CG2-CG 3.78Å; V318-F387 HydrophobicContact CG2-CZ 3.72Å; V318-V390 HydrophobicContact CG1-CG2 4.33Å; V318-L422 HydrophobicContact CG1-CD1 4.5Å
319	T	97.3	Very high	94.8	Very high	11 Å²	11	21.2 Å²	21.2	7%	0.067	11%	0.114	C	C	.	.	H	α-helix	trans	-64.1	-48.5	178.6	-60.9	0	0	0	0	111.9	L315 F317 F321 I322 I323 F355 R386 N426	L315-T319 PolarHBondContact O-N 3.29Å; L315-T319 PolarHBondContact O-OG1 3.47Å; L315-T319 VanDerWaalsContact O-OG1 3.1Å; F317-T319 VanDerWaalsContact C-N 3.31Å; F317-T319 PolarHBondContact O-N 3.36Å; T319-F321 VanDerWaalsContact C-N 3.3Å; T319-F321 PolarHBondContact O-N 3.14Å; T319-I322 PolarHBondContact O-N 3.48Å; T319-I323 PolarHBondContact O-N 3.38Å; T319-F355 HydrophobicContact CG2-CE1 4.46Å; T319-F355 HydrophobicContact CG2-CE2 4.05Å; T319-F355 HydrophobicContact CG2-CZ 3.55Å; T319-R386 PolarHBondContact OG1-NH2 3.49Å; T319-N426 PolarHBondContact OG1-OD1 2.96Å
320	A	94.9	Very high	94.6	Very high	5 Å²	5	21.4 Å²	21.4	4%	0.041	12%	0.115	C	C	.	.	H	α-helix	trans	-70.2	-27	179	0	0	0	0	0	113.1	Y316 F317 I322 L461	Y316-A320 VanDerWaalsContact O-CB 3.23Å; Y316-A320 WeakPolarHBondContact O-CB 3.32Å; Y316-A320 PolarHBondContact O-N 3.25Å; F317-A320 PolarHBondContact O-N 3.01Å; A320-I322 VanDerWaalsContact C-N 3.32Å; A320-L461 HydrophobicContact CB-CD2 4.04Å; A320-L461 WeakPolarHBondContact CB-O 3.33Å
321	F	95.1	Very high	94.3	Very high	25 Å²	25	19 Å²	19	11%	0.11	11%	0.105	C	C	.	.	H	α-helix	trans	-66.8	-36.7	173.6	-167.9	-92.8	0	0	0	111.7	F317 V318 T319 I326 V390 C467 A468 L471	F317-F321 HydrophobicContact CE1-CB 4.4Å; F317-F321 HydrophobicContact CE1-CD2 4.28Å; F317-F321 HydrophobicContact CE1-CG 4.45Å; F317-F321 HydrophobicContact CZ-CD2 4.11Å; F317-F321 WeakPolarHBondContact O-CB 3.3Å; F317-F321 PolarHBondContact O-N 2.94Å; V318-F321 PolarHBondContact O-N 3.19Å; T319-F321 VanDerWaalsContact C-N 3.3Å; T319-F321 PolarHBondContact O-N 3.14Å; F321-I326 HydrophobicContact CD1-CD1 3.61Å; F321-I326 HydrophobicContact CE1-CD1 3.53Å; F321-I326 VanDerWaalsContact O-CD1 3.31Å; F321-I326 WeakPolarHBondContact O-CD1 3.42Å; F321-I326 WeakPolarHBondContact O-CG1 3.49Å; F321-V390 HydrophobicContact CD1-CG1 3.81Å; F321-V390 HydrophobicContact CD1-CG2 4.05Å; F321-V390 HydrophobicContact CE1-CG1 3.5Å; F321-V390 VanDerWaalsContact CE1-CG1 3.5Å; F321-C467 HydrophobicContact CD2-CB 3.67Å; F321-C467 HydrophobicContact CE2-CB 3.57Å; F321-A468 HydrophobicContact CD2-CB 4.32Å; F321-L471 HydrophobicContact CE1-CD2 3.93Å; F321-L471 HydrophobicContact CZ-CB 4.32Å; F321-L471 HydrophobicContact CZ-CD2 3.73Å
322	I	95.6	Very high	94	Very high	0 Å²	0	19.1 Å²	19.1	0%	0	11%	0.107	C	C	.	.	I	π-helix	trans	-87.8	-44.6	-178.4	-63.5	167.6	0	0	0	111.9	V318 T319 A320 I326 S327 L389 V390 F393 L422	V318-I322 HydrophobicContact CG1-CD1 3.9Å; V318-I322 WeakPolarHBondContact O-CG1 3.28Å; V318-I322 PolarHBondContact O-N 2.9Å; T319-I322 PolarHBondContact O-N 3.48Å; A320-I322 VanDerWaalsContact C-N 3.32Å; I322-I326 WeakPolarHBondContact O-CB 3.42Å; I322-I326 PolarHBondContact O-N 3.41Å; I322-I326 VanDerWaalsContact O-N 3.08Å; I322-S327 PolarHBondContact O-N 3.49Å; I322-S327 PolarHBondContact O-OG 3.41Å; I322-L389 HydrophobicContact CD1-CB 3.96Å; I322-V390 HydrophobicContact CD1-CG2 4Å; I322-V390 HydrophobicContact CG1-CG2 4.09Å; I322-F393 HydrophobicContact CD1-CD2 4.02Å; I322-F393 HydrophobicContact CD1-CE2 4.35Å; I322-F393 HydrophobicContact CG2-CB 4.25Å; I322-F393 HydrophobicContact CG2-CD1 3.76Å; I322-F393 HydrophobicContact CG2-CD2 3.79Å; I322-F393 HydrophobicContact CG2-CE1 3.97Å; I322-F393 HydrophobicContact CG2-CE2 3.99Å; I322-F393 HydrophobicContact CG2-CG 3.67Å; I322-F393 HydrophobicContact CG2-CZ 4.08Å; I322-L422 HydrophobicContact CB-CD2 4.17Å; I322-L422 HydrophobicContact CD1-CD1 3.83Å; I322-L422 HydrophobicContact CD1-CD2 4.35Å; I322-L422 HydrophobicContact CG2-CD2 3.84Å
323	I	92.8	Very high	93.6	Very high	23 Å²	23	23.1 Å²	23.1	12%	0.118	13%	0.126	C	C	.	.	I	π-helix	trans	-113.9	129.9	-175	-60.3	-176.1	0	0	0	110.4	T319 V351 F355 L422	T319-I323 PolarHBondContact O-N 3.38Å; I323-V351 HydrophobicContact CG2-CG1 4.35Å; I323-F355 HydrophobicContact CD1-CB 3.86Å; I323-F355 HydrophobicContact CD1-CD1 3.86Å; I323-F355 HydrophobicContact CD1-CD2 3.28Å; I323-F355 HydrophobicContact CD1-CE1 4.26Å; I323-F355 HydrophobicContact CD1-CE2 3.73Å; I323-F355 HydrophobicContact CD1-CG 3.36Å; I323-F355 HydrophobicContact CD1-CZ 4.2Å; I323-L422 HydrophobicContact CD1-CD2 3.65Å; I323-L422 HydrophobicContact CG1-CD2 3.89Å
324	P	88.3	Confident	93.2	Very high	67 Å²	67	26.5 Å²	26.5	44%	0.435	14%	0.139	S	C	.	.	I	π-helix	cis	-86.2	-25.6	-0	31.9	-33.2	0	0	0	114.3	I326 S327 T328 F352	P324-I326 PolarHBondContact O-N 2.91Å; P324-S327 PolarHBondContact O-N 3.09Å; P324-S327 VanDerWaalsContact O-N 3.16Å; P324-S327 PolarHBondContact O-OG 2.89Å; P324-T328 HydrophobicContact CB-CG2 3.73Å; P324-T328 WeakPolarHBondContact O-CG2 3.34Å; P324-T328 PolarHBondContact O-N 3.17Å; P324-T328 PolarHBondContact O-OG1 3.28Å; P324-F352 HydrophobicContact CB-CE1 4.31Å
325	A	85.8	Confident	92.6	Very high	14 Å²	14	30.2 Å²	30.2	12%	0.116	15%	0.154	C	C	.	.	I	π-helix	trans	-45.2	-59	-165.5	0	0	0	0	0	115.1	N329 A468 E472	A325-N329 PolarHBondContact O-ND2 2.89Å; A325-A468 HydrophobicContact CB-CB 3.66Å; A325-E472 WeakPolarHBondContact CA-OE1 3.37Å; A325-E472 HydrophobicContact CB-CG 4.38Å; A325-E472 VanDerWaalsContact CB-OE1 3.29Å; A325-E472 WeakPolarHBondContact CB-OE1 3.5Å
326	I	90.2	Very high	92	Very high	2 Å²	2	34.2 Å²	34.2	1%	0.01	20%	0.196	C	C	.	.	I	π-helix	trans	-73.3	-42.8	-177.1	-60.9	175.3	0	0	0	111	F321 I322 P324 F393 L394 Y398 L471	F321-I326 HydrophobicContact CD1-CD1 3.61Å; F321-I326 HydrophobicContact CE1-CD1 3.53Å; F321-I326 VanDerWaalsContact O-CD1 3.31Å; F321-I326 WeakPolarHBondContact O-CD1 3.42Å; F321-I326 WeakPolarHBondContact O-CG1 3.49Å; I322-I326 WeakPolarHBondContact O-CB 3.42Å; I322-I326 PolarHBondContact O-N 3.41Å; I322-I326 VanDerWaalsContact O-N 3.08Å; P324-I326 PolarHBondContact O-N 2.91Å; I326-F393 HydrophobicContact CG2-CB 4.02Å; I326-L394 HydrophobicContact CD1-CD2 4.03Å; I326-L394 HydrophobicContact CD1-CG 4.38Å; I326-L394 HydrophobicContact CG1-CD2 4.34Å; I326-L394 HydrophobicContact CG2-CD2 3.91Å; I326-L394 HydrophobicContact CG2-CG 4.41Å; I326-Y398 HydrophobicContact CG2-CD2 4.16Å; I326-Y398 HydrophobicContact CG2-CE2 4.32Å; I326-Y398 WeakPolarHBondContact O-CD2 3.38Å; I326-L471 HydrophobicContact CD1-CD2 3.95Å; I326-L471 HydrophobicContact CG1-CD2 4.38Å
327	S	92.4	Very high	91.6	Very high	1 Å²	1	37.9 Å²	37.9	1%	0.007	22%	0.22	C	C	.	.	H	α-helix	trans	-74.6	-34.9	-169.6	60.8	0	0	0	0	113.8	I322 P324 N329 I330 V351	I322-S327 PolarHBondContact O-N 3.49Å; I322-S327 PolarHBondContact O-OG 3.41Å; P324-S327 PolarHBondContact O-N 3.09Å; P324-S327 VanDerWaalsContact O-N 3.16Å; P324-S327 PolarHBondContact O-OG 2.89Å; S327-N329 PolarHBondContact O-N 2.99Å; S327-I330 WeakPolarHBondContact O-CB 3.24Å; S327-I330 PolarHBondContact O-N 3.39Å; S327-I330 VanDerWaalsContact O-N 3.16Å; S327-V351 WeakPolarHBondContact O-CG2 3.02Å; S327-V351 WeakPolarHBondContact OG-CG1 3.42Å
328	T	91.3	Very high	91	Very high	43 Å²	43	38.6 Å²	38.6	26%	0.264	24%	0.239	S	C	.	.	H	α-helix	trans	-70	-23.7	178.9	54.5	0	0	0	0	113	P324 I330 V347 V351 F352	P324-T328 HydrophobicContact CB-CG2 3.73Å; P324-T328 WeakPolarHBondContact O-CG2 3.34Å; P324-T328 PolarHBondContact O-N 3.17Å; P324-T328 PolarHBondContact O-OG1 3.28Å; T328-I330 VanDerWaalsContact C-N 3.28Å; T328-V347 HydrophobicContact CG2-CG1 3.88Å; T328-V351 HydrophobicContact CG2-CG1 4.23Å; T328-F352 HydrophobicContact CG2-CE1 4.43Å; T328-F352 HydrophobicContact CG2-CZ 3.83Å
329	N	90.6	Very high	90.8	Very high	41 Å²	41	40.4 Å²	40.4	22%	0.219	25%	0.252	C	S	.	.	T	Hydrogen-bonded Turn	trans	-79.9	-8.1	174.9	-76.7	-43.4	0	0	0	113	A325 S327 Q331 Y398 Q399 E472	A325-N329 PolarHBondContact O-ND2 2.89Å; S327-N329 PolarHBondContact O-N 2.99Å; N329-Q331 PolarHBondContact O-N 3.27Å; N329-Y398 HydrophobicContact CB-CD2 3.57Å; N329-Y398 HydrophobicContact CB-CE1 4.43Å; N329-Y398 HydrophobicContact CB-CE2 3.2Å; N329-Y398 HydrophobicContact CB-CG 4.32Å; N329-Y398 PolarHBondContact ND2-OH 3.44Å; N329-Y398 CarbonylContact O-C 3.55Å; N329-Q399 WeakPolarHBondContact CB-O 3.41Å; N329-Q399 PolarHBondContact O-N 3.31Å; N329-Q399 PolarHBondContact OD1-O 3.07Å; N329-E472 PolarHBondContact ND2-OE1 3.05Å
330	I	91.8	Very high	90.5	Very high	5 Å²	5	43.3 Å²	43.3	3%	0.026	27%	0.271	C	S	.	.	B	Isolated β-bridge	trans	-76.4	122.6	172.2	-60.6	171.5	0	0	0	109.3	S327 T328 F393 C396 N397 P415	S327-I330 WeakPolarHBondContact O-CB 3.24Å; S327-I330 PolarHBondContact O-N 3.39Å; S327-I330 VanDerWaalsContact O-N 3.16Å; T328-I330 VanDerWaalsContact C-N 3.28Å; I330-F393 HydrophobicContact CD1-CD1 3.67Å; I330-F393 HydrophobicContact CD1-CE1 4.45Å; I330-C396 HydrophobicContact CD1-CB 3.81Å; I330-C396 HydrophobicContact CG1-CB 4.24Å; I330-C396 HydrophobicContact CG2-CB 4.17Å; I330-N397 WeakPolarHBondContact CA-O 3.36Å; I330-P415 HydrophobicContact CD1-CB 4.46Å; I330-P415 HydrophobicContact CG2-CB 4Å; I330-P415 HydrophobicContact CG2-CG 4.14Å
331	Q	91.2	Very high	90.4	Very high	60 Å²	60	51.3 Å²	51.3	28%	0.28	30%	0.3	S	S	.	.			trans	-110.2	147.8	-178.5	-58.7	-167	14	0	0	111.8	N329 M333 K335 N397 Q399	N329-Q331 PolarHBondContact O-N 3.27Å; Q331-M333 PolarHBondContact O-N 3.32Å; Q331-K335 HydrophobicContact CB-CD 4.34Å; Q331-N397 PolarHBondContact N-O 3.03Å; Q331-N397 PolarHBondContact O-ND2 3.3Å; Q331-Q399 HydrophobicContact CB-CG 4.4Å; Q331-Q399 HydrophobicContact CG-CB 4.17Å; Q331-Q399 HydrophobicContact CG-CG 4.23Å
332	S	92.2	Very high	90.2	Very high	4 Å²	4	51.2 Å²	51.2	3%	0.028	30%	0.302	C	S	.	.			trans	-59.5	137.7	172	173	0	0	0	0	110.4	H334 K335 D412	S332-H334 PolarHBondContact O-N 2.86Å; S332-H334 PolarHBondContact OG-N 3.04Å; S332-K335 WeakPolarHBondContact O-CB 3.11Å; S332-K335 PolarHBondContact O-N 3.23Å; S332-K335 VanDerWaalsContact O-N 3.13Å; S332-D412 WeakPolarHBondContact CA-OD1 3.49Å; S332-D412 WeakPolarHBondContact CB-OD2 3.44Å; S332-D412 PolarHBondContact OG-OD2 3.36Å
333	M	90.2	Very high	89.8	Confident	84 Å²	84	54 Å²	54	41%	0.414	32%	0.322	S	S	.	.	T	Hydrogen-bonded Turn	trans	-57.6	-26.8	170.1	-67.6	-119.3	-73.1	0	0	112.7	Q331 Q410 D412	Q331-M333 PolarHBondContact O-N 3.32Å; M333-Q410 HydrophobicContact CE-CB 3.72Å; M333-Q410 WeakPolarHBondContact CG-O 3.37Å; M333-Q410 HydrophobicContact SD-CB 3.57Å; M333-Q410 VanDerWaalsContact SD-CB 3.57Å; M333-Q410 HydrophobicContact SD-CG 4.33Å; M333-D412 WeakPolarHBondContact CG-OD1 3.3Å; M333-D412 PolarHBondContact N-OD1 3.32Å
334	H	89.1	Confident	89.6	Confident	104 Å²	104	57.9 Å²	57.9	48%	0.481	34%	0.338	S	S	.	.	T	Hydrogen-bonded Turn	trans	-96.9	10.6	-177	-56.4	96.5	0	0	0	112.6	S332 G336 T337 T342 D412	S332-H334 PolarHBondContact O-N 2.86Å; S332-H334 PolarHBondContact OG-N 3.04Å; H334-G336 PolarHBondContact O-N 3.19Å; H334-G336 VanDerWaalsContact O-N 3.1Å; H334-T337 HydrophobicContact CB-CG2 4.05Å; H334-T337 VanDerWaalsContact O-CB 3.31Å; H334-T337 WeakPolarHBondContact O-CB 3.31Å; H334-T337 VanDerWaalsContact O-CG2 3.3Å; H334-T337 WeakPolarHBondContact O-CG2 3.46Å; H334-T337 PolarHBondContact O-N 2.45Å; H334-T337 PolarHBondContact O-OG1 3.36Å; H334-T342 HydrophobicContact CB-CG2 3.74Å; H334-T342 PolarHBondContact O-OG1 3.15Å; H334-D412 IonicContact ND1-OD2 3.12Å
335	K	86.2	Confident	89.9	Confident	87 Å²	87	56.1 Å²	56.1	38%	0.378	32%	0.323	S	S	.	.	G	3₁₀ helix	trans	-54.2	-33.2	179.1	-174.8	176.8	177.1	177.7	0	112.8	Q331 S332 T337 G338	Q331-K335 HydrophobicContact CB-CD 4.34Å; S332-K335 WeakPolarHBondContact O-CB 3.11Å; S332-K335 PolarHBondContact O-N 3.23Å; S332-K335 VanDerWaalsContact O-N 3.13Å; K335-T337 PolarHBondContact O-N 3.27Å; K335-G338 PolarHBondContact O-N 3.41Å
336	G	85.5	Confident	90.3	Very high	85 Å²	85	56.3 Å²	56.3	88%	0.876	32%	0.321	S	S	*	.	G	3₁₀ helix	trans	-66.7	-11.9	177	0	0	0	0	0	115.1	H334 G338	H334-G336 PolarHBondContact O-N 3.19Å; H334-G336 VanDerWaalsContact O-N 3.1Å; G336-G338 PolarHBondContact O-N 3.04Å
337	T	88.4	Confident	90.4	Very high	93 Å²	93	57.8 Å²	57.8	57%	0.571	33%	0.33	S	S	*	.	G	3₁₀ helix	trans	-73.2	-11.8	178.3	63.4	0	0	0	0	113.6	H334 K335 S339	H334-T337 HydrophobicContact CB-CG2 4.05Å; H334-T337 VanDerWaalsContact O-CB 3.31Å; H334-T337 WeakPolarHBondContact O-CB 3.31Å; H334-T337 VanDerWaalsContact O-CG2 3.3Å; H334-T337 WeakPolarHBondContact O-CG2 3.46Å; H334-T337 PolarHBondContact O-N 2.45Å; H334-T337 PolarHBondContact O-OG1 3.36Å; K335-T337 PolarHBondContact O-N 3.27Å; T337-S339 PolarHBondContact O-N 3.49Å; T337-S339 PolarHBondContact OG1-N 2.92Å
338	G	85.7	Confident	90.5	Very high	57 Å²	57	58.5 Å²	58.5	59%	0.588	34%	0.335	S	S	*	.			trans	75.7	-0.8	-176	0	0	0	0	0	114.3	K335 G336	K335-G338 PolarHBondContact O-N 3.41Å; G336-G338 PolarHBondContact O-N 3.04Å
339	S	92.8	Very high	90.6	Very high	37 Å²	37	59 Å²	59	26%	0.259	34%	0.336	S	S	.	.			trans	-65.5	126.7	177.6	174.3	0	0	0	0	111.1	T337 W341 T342 S343	T337-S339 PolarHBondContact O-N 3.49Å; T337-S339 PolarHBondContact OG1-N 2.92Å; S339-W341 PolarHBondContact O-N 3.06Å; S339-W341 VanDerWaalsContact O-N 3.08Å; S339-W341 PolarHBondContact OG-N 3.03Å; S339-T342 PolarHBondContact O-N 3.41Å; S339-T342 PolarHBondContact O-OG1 2.94Å; S339-S343 PolarHBondContact O-N 2.97Å; S339-S343 VanDerWaalsContact O-N 3.15Å; S339-S343 PolarHBondContact O-OG 3.1Å; S339-S343 VanDerWaalsContact O-OG 3.11Å
340	P	91.4	Very high	90.8	Very high	73 Å²	73	57.9 Å²	57.9	47%	0.474	33%	0.33	S	S	.	.	H	α-helix	trans	-54.3	-30.3	176.4	-25.8	33.5	0	0	0	113.4	T342 K344 F345	P340-T342 VanDerWaalsContact C-N 3.29Å; P340-T342 PolarHBondContact O-N 3.37Å; P340-K344 WeakPolarHBondContact O-CA 3.47Å; P340-K344 WeakPolarHBondContact O-CB 3.46Å; P340-K344 PolarHBondContact O-N 3.49Å; P340-F345 HydrophobicContact CB-CD2 4.22Å; P340-F345 HydrophobicContact CB-CE2 4.17Å; P340-F345 WeakPolarHBondContact O-CD2 3.47Å; P340-F345 PolarHBondContact O-N 2.8Å
341	W	91.4	Very high	90.9	Very high	173 Å²	173	57.9 Å²	57.9	66%	0.655	33%	0.33	S	S	*	.	H	α-helix	trans	-62.7	-35.9	177.4	-65.2	101.9	0	0	0	112.9	S339 F345 F346 L349	S339-W341 PolarHBondContact O-N 3.06Å; S339-W341 VanDerWaalsContact O-N 3.08Å; S339-W341 PolarHBondContact OG-N 3.03Å; W341-F345 HydrophobicContact CE3-CB 4.42Å; W341-F346 WeakPolarHBondContact O-CA 3.45Å; W341-F346 WeakPolarHBondContact O-CB 3.11Å; W341-F346 PolarHBondContact O-N 3.35Å; W341-L349 HydrophobicContact CE3-CD1 4.02Å; W341-L349 HydrophobicContact CZ3-CD1 4.09Å
342	T	90.7	Very high	91	Very high	22 Å²	22	58 Å²	58	14%	0.135	33%	0.33	C	S	.	.	H	α-helix	trans	-91.5	-24.3	-176.2	62.6	0	0	0	0	112.9	H334 S339 P340 F346	H334-T342 HydrophobicContact CB-CG2 3.74Å; H334-T342 PolarHBondContact O-OG1 3.15Å; S339-T342 PolarHBondContact O-N 3.41Å; S339-T342 PolarHBondContact O-OG1 2.94Å; P340-T342 VanDerWaalsContact C-N 3.29Å; P340-T342 PolarHBondContact O-N 3.37Å; T342-F346 WeakPolarHBondContact O-CB 3.39Å
343	S	88	Confident	91.2	Very high	60 Å²	60	59.9 Å²	59.9	42%	0.42	34%	0.34	S	S	.	.	H	α-helix	trans	-103.5	-48.6	-176.2	59.8	0	0	0	0	113.4	S339	S339-S343 PolarHBondContact O-N 2.97Å; S339-S343 VanDerWaalsContact O-N 3.15Å; S339-S343 PolarHBondContact O-OG 3.1Å; S339-S343 VanDerWaalsContact O-OG 3.11Å
344	K	89.4	Confident	91.5	Very high	104 Å²	104	57.8 Å²	57.8	45%	0.452	33%	0.33	S	S	.	.	T	Hydrogen-bonded Turn	trans	-93.8	-48.1	-173	-155.1	-166.5	-169.8	-167.7	0	111.9	L220 P340 P348	L220-K344 HydrophobicContact CD1-CD 4.07Å; L220-K344 HydrophobicContact CD1-CG 4.16Å; L220-K344 HydrophobicContact CD2-CD 4.29Å; L220-K344 HydrophobicContact CD2-CG 4.06Å; L220-K344 HydrophobicContact CG-CD 3.9Å; L220-K344 HydrophobicContact CG-CG 4.15Å; L220-K344 PolarHBondContact O-NZ 3.2Å; P340-K344 WeakPolarHBondContact O-CA 3.47Å; P340-K344 WeakPolarHBondContact O-CB 3.46Å; P340-K344 PolarHBondContact O-N 3.49Å; K344-P348 WeakPolarHBondContact O-CD 3.49Å
345	F	93.3	Very high	91.9	Very high	29 Å²	29	53.7 Å²	53.7	13%	0.127	31%	0.311	C	S	.	.	S	Bend	trans	-93.1	-17	-171.3	-65.5	-73.5	0	0	0	114.4	L217 L220 A221 P340 W341 V347 P348 L349	L217-F345 HydrophobicContact CD2-CD1 3.83Å; L220-F345 HydrophobicContact CB-CE1 4.02Å; L220-F345 HydrophobicContact CD2-CD1 3.59Å; L220-F345 HydrophobicContact CD2-CE1 3.61Å; L220-F345 HydrophobicContact CD2-CG 4.44Å; L220-F345 HydrophobicContact CD2-CZ 4.46Å; L220-F345 HydrophobicContact CG-CD1 4.33Å; L220-F345 HydrophobicContact CG-CE1 3.83Å; L220-F345 HydrophobicContact CG-CZ 4.4Å; A221-F345 HydrophobicContact CB-CE1 4.21Å; A221-F345 HydrophobicContact CB-CZ 4.06Å; P340-F345 HydrophobicContact CB-CD2 4.22Å; P340-F345 HydrophobicContact CB-CE2 4.17Å; P340-F345 WeakPolarHBondContact O-CD2 3.47Å; P340-F345 PolarHBondContact O-N 2.8Å; W341-F345 HydrophobicContact CE3-CB 4.42Å; F345-V347 PolarHBondContact O-N 3.4Å; F345-P348 WeakPolarHBondContact O-CD 3.44Å; F345-L349 HydrophobicContact CB-CD1 3.71Å; F345-L349 HydrophobicContact CB-CG 4.24Å; F345-L349 VanDerWaalsContact O-CB 3.24Å; F345-L349 WeakPolarHBondContact O-CB 3.34Å; F345-L349 VanDerWaalsContact O-CG 3.25Å; F345-L349 WeakPolarHBondContact O-CG 3.32Å; F345-L349 PolarHBondContact O-N 3.26Å
346	F	94.4	Very high	92.3	Very high	18 Å²	18	51.1 Å²	51.1	8%	0.079	30%	0.301	C	S	.	.	H	α-helix	trans	-54.9	-52.7	-173.7	-178.7	-101.3	0	0	0	112.5	W341 T342 T350 D412 P415	W341-F346 WeakPolarHBondContact O-CA 3.45Å; W341-F346 WeakPolarHBondContact O-CB 3.11Å; W341-F346 PolarHBondContact O-N 3.35Å; T342-F346 WeakPolarHBondContact O-CB 3.39Å; F346-T350 HydrophobicContact CD2-CG2 3.96Å; F346-T350 HydrophobicContact CE2-CG2 3.77Å; F346-T350 HydrophobicContact CZ-CG2 4.15Å; F346-T350 WeakPolarHBondContact O-CB 3.41Å; F346-T350 WeakPolarHBondContact O-CG2 3.43Å; F346-T350 PolarHBondContact O-N 3.38Å; F346-T350 PolarHBondContact O-OG1 2.98Å; F346-D412 HydrophobicContact CE2-CB 4.06Å; F346-D412 HydrophobicContact CZ-CB 4.44Å; F346-P415 HydrophobicContact CZ-CG 4.34Å
347	V	92.9	Very high	92.9	Very high	33 Å²	33	52.5 Å²	52.5	20%	0.2	28%	0.283	C	S	.	.	H	α-helix	trans	-66.4	-51.7	-179.3	172	0	0	0	0	111.2	T328 F345 L349 T350 V351 F352	T328-V347 HydrophobicContact CG2-CG1 3.88Å; F345-V347 PolarHBondContact O-N 3.4Å; V347-L349 VanDerWaalsContact C-N 3.29Å; V347-L349 PolarHBondContact O-N 3.47Å; V347-T350 PolarHBondContact O-N 2.78Å; V347-V351 HydrophobicContact CG1-CB 4.23Å; V347-V351 HydrophobicContact CG1-CG2 4.07Å; V347-V351 WeakPolarHBondContact O-CA 3.25Å; V347-V351 VanDerWaalsContact O-CB 3.24Å; V347-V351 WeakPolarHBondContact O-CB 3.24Å; V347-V351 PolarHBondContact O-N 3.49Å; V347-F352 HydrophobicContact CG1-CE2 4.39Å
348	P	93.1	Very high	93.4	Very high	16 Å²	16	48.3 Å²	48.3	10%	0.104	26%	0.258	C	S	.	.	I	π-helix	trans	-56.2	-38.3	176.5	-28.7	36.2	0	0	0	115	L216 L217 L220 K344 F345 F352 L353	L216-P348 HydrophobicContact CD2-CB 4.34Å; L217-P348 HydrophobicContact CD2-CB 3.65Å; L217-P348 HydrophobicContact CG-CB 4.38Å; L220-P348 HydrophobicContact CD2-CG 4.11Å; K344-P348 WeakPolarHBondContact O-CD 3.49Å; F345-P348 WeakPolarHBondContact O-CD 3.44Å; P348-F352 HydrophobicContact CB-CD2 4.47Å; P348-F352 WeakPolarHBondContact O-CB 3.42Å; P348-F352 PolarHBondContact O-N 3.35Å; P348-L353 PolarHBondContact O-N 2.86Å
349	L	94.9	Very high	93.9	Very high	55 Å²	55	45.9 Å²	45.9	29%	0.288	23%	0.232	S	C	.	.	I	π-helix	trans	-71.3	-53.5	177.7	-73.6	168.7	0	0	0	112	L217 W341 F345 V347 L353 L354	L217-L349 HydrophobicContact CD1-CD2 3.64Å; L217-L349 HydrophobicContact CD1-CG 4.43Å; L217-L349 HydrophobicContact CD2-CD2 3.95Å; L217-L349 HydrophobicContact CD2-CG 3.94Å; L217-L349 HydrophobicContact CG-CD2 4.48Å; W341-L349 HydrophobicContact CE3-CD1 4.02Å; W341-L349 HydrophobicContact CZ3-CD1 4.09Å; F345-L349 HydrophobicContact CB-CD1 3.71Å; F345-L349 HydrophobicContact CB-CG 4.24Å; F345-L349 VanDerWaalsContact O-CB 3.24Å; F345-L349 WeakPolarHBondContact O-CB 3.34Å; F345-L349 VanDerWaalsContact O-CG 3.25Å; F345-L349 WeakPolarHBondContact O-CG 3.32Å; F345-L349 PolarHBondContact O-N 3.26Å; V347-L349 VanDerWaalsContact C-N 3.29Å; V347-L349 PolarHBondContact O-N 3.47Å; L349-L353 HydrophobicContact CD2-CD2 4.07Å; L349-L354 VanDerWaalsContact O-CB 3.3Å; L349-L354 WeakPolarHBondContact O-CB 3.33Å; L349-L354 PolarHBondContact O-N 2.64Å
350	T	94.2	Very high	94.2	Very high	17 Å²	17	45 Å²	45	10%	0.104	22%	0.224	C	C	.	.	I	π-helix	trans	-82.7	-27.8	-169.6	61.4	0	0	0	0	113.6	F346 V347 V416 T419	F346-T350 HydrophobicContact CD2-CG2 3.96Å; F346-T350 HydrophobicContact CE2-CG2 3.77Å; F346-T350 HydrophobicContact CZ-CG2 4.15Å; F346-T350 WeakPolarHBondContact O-CB 3.41Å; F346-T350 WeakPolarHBondContact O-CG2 3.43Å; F346-T350 PolarHBondContact O-N 3.38Å; F346-T350 PolarHBondContact O-OG1 2.98Å; V347-T350 PolarHBondContact O-N 2.78Å; T350-V416 HydrophobicContact CG2-CG2 3.79Å; T350-T419 WeakPolarHBondContact O-CG2 2.95Å; T350-T419 PolarHBondContact O-OG1 3.41Å
351	V	94.1	Very high	94.5	Very high	4 Å²	4	43.6 Å²	43.6	2%	0.024	22%	0.216	C	C	.	.	I	π-helix	trans	-99	-50.1	-178.2	179.2	0	0	0	0	111.4	I323 S327 T328 V347 F355	I323-V351 HydrophobicContact CG2-CG1 4.35Å; S327-V351 WeakPolarHBondContact O-CG2 3.02Å; S327-V351 WeakPolarHBondContact OG-CG1 3.42Å; T328-V351 HydrophobicContact CG2-CG1 4.23Å; V347-V351 HydrophobicContact CG1-CB 4.23Å; V347-V351 HydrophobicContact CG1-CG2 4.07Å; V347-V351 WeakPolarHBondContact O-CA 3.25Å; V347-V351 VanDerWaalsContact O-CB 3.24Å; V347-V351 WeakPolarHBondContact O-CB 3.24Å; V347-V351 PolarHBondContact O-N 3.49Å; V351-F355 WeakPolarHBondContact O-CB 3.22Å
352	F	93	Very high	94.8	Very high	64 Å²	64	35.5 Å²	35.5	28%	0.281	19%	0.185	S	C	.	.	I	π-helix	trans	-88	-57.9	-174.1	-59.4	-51.7	0	0	0	112.2	A213 L216 P324 T328 V347 P348 N356	A213-F352 HydrophobicContact CB-CB 4.2Å; L216-F352 HydrophobicContact CD2-CD2 3.95Å; P324-F352 HydrophobicContact CB-CE1 4.31Å; T328-F352 HydrophobicContact CG2-CE1 4.43Å; T328-F352 HydrophobicContact CG2-CZ 3.83Å; V347-F352 HydrophobicContact CG1-CE2 4.39Å; P348-F352 HydrophobicContact CB-CD2 4.47Å; P348-F352 WeakPolarHBondContact O-CB 3.42Å; P348-F352 PolarHBondContact O-N 3.35Å; F352-N356 WeakPolarHBondContact O-CB 3.4Å; F352-N356 PolarHBondContact O-N 3.22Å; F352-N356 PolarHBondContact O-ND2 3.22Å
353	L	95.9	Very high	95.1	Very high	42 Å²	42	35.2 Å²	35.2	22%	0.22	18%	0.182	C	C	.	.	I	π-helix	trans	-65.1	-51.5	-176.2	178.8	64.9	0	0	0	111.4	T210 A213 V214 L217 P348 L349 F355 N356 F357	T210-L353 HydrophobicContact CG2-CD1 4.32Å; A213-L353 HydrophobicContact CB-CB 4.15Å; A213-L353 HydrophobicContact CB-CD1 4.19Å; V214-L353 HydrophobicContact CG2-CD1 3.66Å; L217-L353 HydrophobicContact CD1-CB 4.03Å; L217-L353 HydrophobicContact CD1-CD2 3.61Å; L217-L353 HydrophobicContact CD1-CG 4.31Å; P348-L353 PolarHBondContact O-N 2.86Å; L349-L353 HydrophobicContact CD2-CD2 4.07Å; L353-F355 PolarHBondContact O-N 3.18Å; L353-N356 PolarHBondContact O-N 3.11Å; L353-F357 VanDerWaalsContact O-CB 3.31Å; L353-F357 WeakPolarHBondContact O-CB 3.33Å; L353-F357 PolarHBondContact O-N 2.81Å
354	L	97.1	Very high	95.5	Very high	40 Å²	40	34.5 Å²	34.5	21%	0.209	17%	0.172	C	C	.	.	H	α-helix	trans	-63.1	-42.4	-176.1	-171.7	64.7	0	0	0	112.2	L349 A358 V416 T419 C420	L349-L354 VanDerWaalsContact O-CB 3.3Å; L349-L354 WeakPolarHBondContact O-CB 3.33Å; L349-L354 PolarHBondContact O-N 2.64Å; L354-A358 WeakPolarHBondContact O-CB 3.48Å; L354-A358 PolarHBondContact O-N 2.9Å; L354-V416 HydrophobicContact CD2-CB 4.14Å; L354-V416 HydrophobicContact CD2-CG1 3.69Å; L354-V416 HydrophobicContact CD2-CG2 4.37Å; L354-V416 WeakPolarHBondContact CD2-O 3.35Å; L354-T419 HydrophobicContact CB-CG2 4.3Å; L354-T419 HydrophobicContact CD2-CG2 4.36Å; L354-T419 HydrophobicContact CG-CG2 4.32Å; L354-C420 VanDerWaalsContact CD1-SG 3.56Å
355	F	97.1	Very high	95.8	Very high	19 Å²	19	32.2 Å²	32.2	8%	0.083	17%	0.167	C	C	.	.	H	α-helix	trans	-62.2	-51.6	175.7	174.5	-103.2	0	0	0	111.4	T319 I323 V351 L353 F357 A358 D359 T419 L422 N426	T319-F355 HydrophobicContact CG2-CE1 4.46Å; T319-F355 HydrophobicContact CG2-CE2 4.05Å; T319-F355 HydrophobicContact CG2-CZ 3.55Å; I323-F355 HydrophobicContact CD1-CB 3.86Å; I323-F355 HydrophobicContact CD1-CD1 3.86Å; I323-F355 HydrophobicContact CD1-CD2 3.28Å; I323-F355 HydrophobicContact CD1-CE1 4.26Å; I323-F355 HydrophobicContact CD1-CE2 3.73Å; I323-F355 HydrophobicContact CD1-CG 3.36Å; I323-F355 HydrophobicContact CD1-CZ 4.2Å; V351-F355 WeakPolarHBondContact O-CB 3.22Å; L353-F355 PolarHBondContact O-N 3.18Å; F355-F357 VanDerWaalsContact C-N 3.31Å; F355-F357 PolarHBondContact O-N 3.33Å; F355-A358 PolarHBondContact O-N 3.44Å; F355-D359 VanDerWaalsContact O-CB 3.27Å; F355-D359 WeakPolarHBondContact O-CB 3.11Å; F355-D359 PolarHBondContact O-N 3.47Å; F355-T419 HydrophobicContact CB-CG2 3.61Å; F355-L422 HydrophobicContact CD2-CD2 4.23Å; F355-L422 HydrophobicContact CD2-CG 4.37Å; F355-L422 HydrophobicContact CE2-CD2 4.15Å; F355-L422 HydrophobicContact CE2-CG 4.06Å; F355-N426 HydrophobicContact CE2-CB 4.43Å
356	N	96	Very high	96	Very high	32 Å²	32	30.9 Å²	30.9	17%	0.171	16%	0.161	C	C	.	.	H	α-helix	trans	-63.3	-38.9	-176.9	-81	-77.8	0	0	0	111.7	G209 T210 F352 L353 L360	G209-N356 VanDerWaalsContact CA-OD1 3.31Å; G209-N356 WeakPolarHBondContact CA-OD1 3.42Å; T210-N356 PolarHBondContact OG1-O 3.15Å; F352-N356 WeakPolarHBondContact O-CB 3.4Å; F352-N356 PolarHBondContact O-N 3.22Å; F352-N356 PolarHBondContact O-ND2 3.22Å; L353-N356 PolarHBondContact O-N 3.11Å; N356-L360 WeakPolarHBondContact O-CB 3.32Å; N356-L360 PolarHBondContact O-N 3.21Å
357	F	97.4	Very high	95.9	Very high	114 Å²	114	31 Å²	31	50%	0.5	17%	0.166	S	C	.	.	H	α-helix	trans	-68.3	-44.8	176.4	-174.9	-102.5	0	0	0	112	T210 L353 F355 D359 L360 C361	T210-F357 HydrophobicContact CG2-CD2 4.36Å; L353-F357 VanDerWaalsContact O-CB 3.31Å; L353-F357 WeakPolarHBondContact O-CB 3.33Å; L353-F357 PolarHBondContact O-N 2.81Å; F355-F357 VanDerWaalsContact C-N 3.31Å; F355-F357 PolarHBondContact O-N 3.33Å; F357-D359 VanDerWaalsContact C-N 3.34Å; F357-D359 PolarHBondContact O-N 2.64Å; F357-L360 WeakPolarHBondContact O-CB 3.47Å; F357-L360 PolarHBondContact O-N 3.44Å; F357-C361 PolarHBondContact O-N 3.25Å; F357-C361 PolarHBondContact O-SG 3.18Å; F357-C361 VanDerWaalsContact O-SG 3.35Å
358	A	98	Very high	95.8	Very high	6 Å²	6	38.3 Å²	38.3	5%	0.05	19%	0.19	C	C	.	.	H	α-helix	trans	-63.2	-40.1	175.4	0	0	0	0	0	111.9	L354 F355 C361 G362 L424	L354-A358 WeakPolarHBondContact O-CB 3.48Å; L354-A358 PolarHBondContact O-N 2.9Å; F355-A358 PolarHBondContact O-N 3.44Å; A358-C361 PolarHBondContact O-N 2.86Å; A358-G362 PolarHBondContact O-N 2.91Å; A358-L424 HydrophobicContact CB-CG 4.19Å; A358-L424 WeakPolarHBondContact O-CA 3.36Å; A358-L424 WeakPolarHBondContact O-CD2 3.44Å
359	D	97.9	Very high	95.9	Very high	6 Å²	6	41.9 Å²	41.9	3%	0.032	21%	0.207	C	C	.	.	H	α-helix	trans	-59.2	-51.2	172.3	-172.1	70	0	0	0	110.4	A206 F355 F357 C361 G362 R363 G423 N426 G427	A206-D359 WeakPolarHBondContact CB-OD2 3.47Å; F355-D359 VanDerWaalsContact O-CB 3.27Å; F355-D359 WeakPolarHBondContact O-CB 3.11Å; F355-D359 PolarHBondContact O-N 3.47Å; F357-D359 VanDerWaalsContact C-N 3.34Å; F357-D359 PolarHBondContact O-N 2.64Å; D359-C361 VanDerWaalsContact C-N 3.34Å; D359-C361 PolarHBondContact O-N 3.34Å; D359-G362 PolarHBondContact O-N 3.44Å; D359-G362 VanDerWaalsContact O-N 3.08Å; D359-R363 VanDerWaalsContact O-CG 3.31Å; D359-R363 WeakPolarHBondContact O-CG 3.44Å; D359-R363 PolarHBondContact O-N 3.14Å; D359-R363 IonicContact OD1-CZ 3.26Å; D359-R363 IonicContact OD1-NE 3.52Å; D359-R363 IonicContact OD1-NH2 3.83Å; D359-R363 PolarHBondContact OD1-NH2 3.31Å; D359-R363 IonicContact OD2-CZ 2.98Å; D359-R363 VanDerWaalsContact OD2-CZ 3.3Å; D359-R363 IonicContact OD2-NE 3.86Å; D359-R363 PolarHBondContact OD2-NE 3Å; D359-R363 IonicContact OD2-NH2 2.75Å; D359-R363 PolarHBondContact OD2-NH2 3.12Å; D359-G423 VanDerWaalsContact CA-O 3.27Å; D359-G423 WeakPolarHBondContact CA-O 3.11Å; D359-N426 PolarHBondContact OD1-ND2 2.89Å; D359-G427 WeakPolarHBondContact O-CA 3.29Å; D359-G427 WeakPolarHBondContact OD1-CA 3.37Å; D359-G427 PolarHBondContact OD1-N 3.45Å
360	L	97.7	Very high	95.8	Very high	17 Å²	17	40.7 Å²	40.7	9%	0.089	20%	0.2	C	C	.	.	H	α-helix	trans	-54.3	-47.5	175.3	174.9	64.1	0	0	0	112.1	S203 A206 M207 N356 F357 G362 R363 Q364	S203-L360 WeakPolarHBondContact O-CD1 3.31Å; A206-L360 HydrophobicContact CB-CB 3.95Å; A206-L360 HydrophobicContact CB-CD1 4.19Å; M207-L360 HydrophobicContact CB-CD1 4.15Å; M207-L360 HydrophobicContact CE-CD1 4.5Å; M207-L360 HydrophobicContact CE-CD2 3.57Å; M207-L360 HydrophobicContact SD-CD2 4.08Å; N356-L360 WeakPolarHBondContact O-CB 3.32Å; N356-L360 PolarHBondContact O-N 3.21Å; F357-L360 WeakPolarHBondContact O-CB 3.47Å; F357-L360 PolarHBondContact O-N 3.44Å; L360-G362 PolarHBondContact O-N 2.91Å; L360-R363 PolarHBondContact O-N 3.28Å; L360-Q364 WeakPolarHBondContact O-CB 3.31Å; L360-Q364 PolarHBondContact O-N 3.44Å
361	C	98	Very high	95.7	Very high	45 Å²	45	44 Å²	44	30%	0.304	22%	0.219	S	C	.	.	H	α-helix	trans	-58.3	-47.2	175.8	-70.6	0	0	0	0	111.4	F357 A358 D359 R363 Q364 V365 L424	F357-C361 PolarHBondContact O-N 3.25Å; F357-C361 PolarHBondContact O-SG 3.18Å; F357-C361 VanDerWaalsContact O-SG 3.35Å; A358-C361 PolarHBondContact O-N 2.86Å; D359-C361 VanDerWaalsContact C-N 3.34Å; D359-C361 PolarHBondContact O-N 3.34Å; C361-R363 VanDerWaalsContact C-N 3.35Å; C361-R363 PolarHBondContact O-N 3.41Å; C361-Q364 PolarHBondContact O-N 3.09Å; C361-Q364 VanDerWaalsContact O-N 3.15Å; C361-V365 WeakPolarHBondContact O-CG2 3.47Å; C361-V365 PolarHBondContact O-N 2.78Å; C361-L424 HydrophobicContact CB-CD2 3.76Å
362	G	97.9	Very high	95.7	Very high	2 Å²	2	44.8 Å²	44.8	2%	0.021	23%	0.225	C	C	.	.	H	α-helix	trans	-58.3	-44.8	177.3	0	0	0	0	0	112.4	A358 D359 L360 Q364 V365 G427 Y428	A358-G362 PolarHBondContact O-N 2.91Å; D359-G362 PolarHBondContact O-N 3.44Å; D359-G362 VanDerWaalsContact O-N 3.08Å; L360-G362 PolarHBondContact O-N 2.91Å; G362-Q364 VanDerWaalsContact C-N 3.33Å; G362-Q364 PolarHBondContact O-N 2.9Å; G362-V365 PolarHBondContact O-N 2.69Å; G362-G427 VanDerWaalsContact C-C 3.48Å; G362-Y428 WeakPolarHBondContact O-CA 3.35Å
363	R	97.6	Very high	95.5	Very high	16 Å²	16	41.8 Å²	41.8	6%	0.06	21%	0.212	C	C	.	.	H	α-helix	trans	-63.7	-39.9	175.7	-60.9	-171.4	-176	-75.7	-9.8	111.5	Q199 I202 A206 D359 L360 C361 T366 G427 S430 T431	Q199-R363 PolarHBondContact NE2-O 2.95Å; I202-R363 HydrophobicContact CG2-CG 4.48Å; I202-R363 WeakPolarHBondContact O-CD 3.38Å; A206-R363 HydrophobicContact CB-CG 4.47Å; D359-R363 VanDerWaalsContact O-CG 3.31Å; D359-R363 WeakPolarHBondContact O-CG 3.44Å; D359-R363 PolarHBondContact O-N 3.14Å; D359-R363 IonicContact OD1-CZ 3.26Å; D359-R363 IonicContact OD1-NE 3.52Å; D359-R363 IonicContact OD1-NH2 3.83Å; D359-R363 PolarHBondContact OD1-NH2 3.31Å; D359-R363 IonicContact OD2-CZ 2.98Å; D359-R363 VanDerWaalsContact OD2-CZ 3.3Å; D359-R363 IonicContact OD2-NE 3.86Å; D359-R363 PolarHBondContact OD2-NE 3Å; D359-R363 IonicContact OD2-NH2 2.75Å; D359-R363 PolarHBondContact OD2-NH2 3.12Å; L360-R363 PolarHBondContact O-N 3.28Å; C361-R363 VanDerWaalsContact C-N 3.35Å; C361-R363 PolarHBondContact O-N 3.41Å; R363-T366 PolarHBondContact O-N 2.99Å; R363-T366 PolarHBondContact O-OG1 2.94Å; R363-G427 VanDerWaalsContact CG-CA 3.49Å; R363-G427 WeakPolarHBondContact CG-O 3.44Å; R363-S430 PolarHBondContact NH1-OG 3.27Å; R363-S430 PolarHBondContact NH2-OG 3.25Å; R363-T431 VanDerWaalsContact CG-OG1 3.26Å; R363-T431 WeakPolarHBondContact CG-OG1 3.37Å; R363-T431 PolarHBondContact NH1-OG1 3.25Å
364	Q	95.8	Very high	95.2	Very high	45 Å²	45	41.8 Å²	41.8	21%	0.21	21%	0.214	C	C	.	.	H	α-helix	trans	-69.8	-34.5	-176.8	-165.2	50.6	58.5	0	0	112.1	Y54 S203 L360 C361 G362 T366 A367 W368	Y54-Q364 PolarHBondContact OH-NE2 3.08Å; S203-Q364 PolarHBondContact OG-OE1 3.42Å; S203-Q364 VanDerWaalsContact OG-OE1 3.05Å; L360-Q364 WeakPolarHBondContact O-CB 3.31Å; L360-Q364 PolarHBondContact O-N 3.44Å; C361-Q364 PolarHBondContact O-N 3.09Å; C361-Q364 VanDerWaalsContact O-N 3.15Å; G362-Q364 VanDerWaalsContact C-N 3.33Å; G362-Q364 PolarHBondContact O-N 2.9Å; Q364-T366 PolarHBondContact O-N 3.49Å; Q364-A367 VanDerWaalsContact O-CB 3.23Å; Q364-A367 WeakPolarHBondContact O-CB 3.45Å; Q364-A367 PolarHBondContact O-N 3.44Å; Q364-W368 HydrophobicContact CB-CZ3 4.47Å; Q364-W368 HydrophobicContact CG-CH2 3.72Å; Q364-W368 HydrophobicContact CG-CZ3 3.77Å; Q364-W368 WeakPolarHBondContact O-CZ3 3.44Å
365	V	96.4	Very high	94.7	Very high	57 Å²	57	48.7 Å²	48.7	35%	0.345	24%	0.238	S	C	.	.	H	α-helix	trans	-56.5	-33.2	174.5	174.8	0	0	0	0	111.8	C361 G362 A367 W368 I369 Y428	C361-V365 WeakPolarHBondContact O-CG2 3.47Å; C361-V365 PolarHBondContact O-N 2.78Å; G362-V365 PolarHBondContact O-N 2.69Å; V365-A367 PolarHBondContact O-N 2.89Å; V365-A367 VanDerWaalsContact O-N 3.17Å; V365-W368 PolarHBondContact O-N 3.29Å; V365-I369 HydrophobicContact CG1-CB 4.34Å; V365-I369 HydrophobicContact CG1-CD1 4.36Å; V365-I369 PolarHBondContact O-N 2.96Å; V365-Y428 HydrophobicContact CB-CD2 4.11Å; V365-Y428 HydrophobicContact CB-CE2 4.31Å; V365-Y428 HydrophobicContact CG1-CD2 3.99Å; V365-Y428 HydrophobicContact CG1-CE2 3.75Å
366	T	95.9	Very high	94.4	Very high	0 Å²	0	49.7 Å²	49.7	0%	0	25%	0.247	C	C	.	.	T	Hydrogen-bonded Turn	trans	-68.1	-11.1	178.5	70.5	0	0	0	0	114.8	Q199 R363 Q364 W368 Q370 Y428 T431 L432	Q199-T366 WeakPolarHBondContact CG-OG1 3.06Å; R363-T366 PolarHBondContact O-N 2.99Å; R363-T366 PolarHBondContact O-OG1 2.94Å; Q364-T366 PolarHBondContact O-N 3.49Å; T366-W368 PolarHBondContact O-N 3.4Å; T366-Q370 WeakPolarHBondContact O-CG 3.29Å; T366-Q370 PolarHBondContact O-NE2 3.47Å; T366-Q370 VanDerWaalsContact O-NE2 3.17Å; T366-Y428 HydrophobicContact CG2-CD2 3.43Å; T366-Y428 VanDerWaalsContact CG2-CD2 3.43Å; T366-Y428 HydrophobicContact CG2-CE2 3.64Å; T366-Y428 HydrophobicContact CG2-CG 4.15Å; T366-T431 HydrophobicContact CG2-CG2 4.18Å; T366-T431 WeakPolarHBondContact OG1-CG2 3.31Å; T366-L432 HydrophobicContact CG2-CD2 3.83Å; T366-L432 HydrophobicContact CG2-CG 4.08Å
367	A	92.3	Very high	94.2	Very high	22 Å²	22	56.7 Å²	56.7	18%	0.182	28%	0.276	C	S	.	.	T	Hydrogen-bonded Turn	trans	-66.2	-28.7	170.1	0	0	0	0	0	112.1	Q364 V365	Q364-A367 VanDerWaalsContact O-CB 3.23Å; Q364-A367 WeakPolarHBondContact O-CB 3.45Å; Q364-A367 PolarHBondContact O-N 3.44Å; V365-A367 PolarHBondContact O-N 2.89Å; V365-A367 VanDerWaalsContact O-N 3.17Å
368	W	92.2	Very high	94.1	Very high	186 Å²	186	56 Å²	56	71%	0.705	28%	0.277	S	S	*	.	T	Hydrogen-bonded Turn	trans	-110.9	-35.5	-178	-54.6	-77.8	0	0	0	112.8	Q364 V365 T366	Q364-W368 HydrophobicContact CB-CZ3 4.47Å; Q364-W368 HydrophobicContact CG-CH2 3.72Å; Q364-W368 HydrophobicContact CG-CZ3 3.77Å; Q364-W368 WeakPolarHBondContact O-CZ3 3.44Å; V365-W368 PolarHBondContact O-N 3.29Å; T366-W368 PolarHBondContact O-N 3.4Å
369	I	93.9	Very high	94	Very high	91 Å²	91	55.8 Å²	55.8	47%	0.467	28%	0.275	S	S	.	.			trans	-125.9	105.9	-172.2	-53.1	176.4	0	0	0	109.9	V365 V371 Y428	V365-I369 HydrophobicContact CG1-CB 4.34Å; V365-I369 HydrophobicContact CG1-CD1 4.36Å; V365-I369 PolarHBondContact O-N 2.96Å; I369-V371 HydrophobicContact CG2-CB 4.27Å; I369-V371 HydrophobicContact CG2-CG2 3.92Å; I369-Y428 VanDerWaalsContact O-CE2 3.3Å; I369-Y428 WeakPolarHBondContact O-CE2 3.34Å; I369-Y428 PolarHBondContact O-OH 2.83Å
370	Q	93.1	Very high	93.9	Very high	30 Å²	30	56.8 Å²	56.8	14%	0.14	28%	0.282	C	S	.	.			trans	-109.6	55.3	-179.9	-62.5	177.6	2.8	0	0	111.6	Y17 M195 T366 L432 I435 Y436	Y17-Q370 PolarHBondContact OH-O 3.07Å; M195-Q370 VanDerWaalsContact CE-OE1 3.24Å; T366-Q370 WeakPolarHBondContact O-CG 3.29Å; T366-Q370 PolarHBondContact O-NE2 3.47Å; T366-Q370 VanDerWaalsContact O-NE2 3.17Å; Q370-L432 HydrophobicContact CB-CD2 4.12Å; Q370-L432 HydrophobicContact CG-CD2 4.3Å; Q370-I435 HydrophobicContact CG-CD1 4.3Å; Q370-Y436 VanDerWaalsContact C-OH 3.29Å; Q370-Y436 PolarHBondContact O-OH 3.11Å
371	V	93	Very high	93.9	Very high	85 Å²	85	58 Å²	58	52%	0.515	30%	0.298	S	S	.	.			trans	-101.3	138.8	179.4	175.8	0	0	0	0	108.1	I369 Y428 L432	I369-V371 HydrophobicContact CG2-CB 4.27Å; I369-V371 HydrophobicContact CG2-CG2 3.92Å; V371-Y428 PolarHBondContact N-OH 3.3Å; V371-Y428 WeakPolarHBondContact O-CE1 3.19Å; V371-Y428 PolarHBondContact O-OH 2.73Å; V371-L432 WeakPolarHBondContact O-CD1 3.48Å
372	P	93.2	Very high	93.8	Very high	22 Å²	22	59 Å²	59	14%	0.143	30%	0.3	C	S	.	.	S	Bend	cis	-102.8	6.9	18.9	39.5	-36.8	0	0	0	116.3	S376 L378 L379	P372-S376 WeakPolarHBondContact CB-OG 3.17Å; P372-S376 WeakPolarHBondContact O-CB 3.26Å; P372-L378 HydrophobicContact CB-CB 4.09Å; P372-L378 HydrophobicContact CB-CD2 4.01Å; P372-L378 HydrophobicContact CB-CG 4.46Å; P372-L378 HydrophobicContact CG-CB 4.02Å; P372-L378 HydrophobicContact CG-CD2 4.39Å; P372-L378 HydrophobicContact CG-CG 4.39Å; P372-L379 HydrophobicContact CG-CB 3.84Å
373	G	89.4	Confident	93.8	Very high	1 Å²	1	58.9 Å²	58.9	1%	0.01	30%	0.299	C	S	.	.			trans	97.2	161.3	-178.6	0	0	0	0	0	114.3	Y17 R375 S376 Y436	Y17-G373 VanDerWaalsContact CE1-CA 3.45Å; G373-R375 VanDerWaalsContact C-N 3.35Å; G373-R375 PolarHBondContact O-N 2.89Å; G373-S376 PolarHBondContact O-N 3.08Å; G373-Y436 VanDerWaalsContact C-CE2 3.42Å; G373-Y436 WeakPolarHBondContact CA-OH 3.42Å; G373-Y436 PolarHBondContact N-OH 3.35Å
374	P	88.7	Confident	93.7	Very high	41 Å²	41	61.4 Å²	61.4	27%	0.266	32%	0.316	S	S	.	.	T	Hydrogen-bonded Turn	trans	-67.6	-28.9	-170.9	25.3	-34.9	0	0	0	114.5	Y436 I440	P374-Y436 HydrophobicContact CB-CD1 4Å; P374-Y436 HydrophobicContact CB-CD2 4.07Å; P374-Y436 HydrophobicContact CB-CG 3.72Å; P374-Y436 HydrophobicContact CG-CD1 4.31Å; P374-I440 HydrophobicContact CB-CG2 3.71Å; P374-I440 HydrophobicContact CG-CG2 4.42Å
375	R	86.8	Confident	93.8	Very high	185 Å²	185	62.3 Å²	62.3	70%	0.698	33%	0.327	S	S	*	.	T	Hydrogen-bonded Turn	trans	-100	-0.2	-178	-64.2	-174.8	-179.7	-174.2	-1.2	113.2	E29 G373	E29-R375 IonicContact OE2-CZ 3.84Å; E29-R375 IonicContact OE2-NH1 3.76Å; E29-R375 IonicContact OE2-NH2 3.3Å; E29-R375 PolarHBondContact OE2-NH2 2.83Å; E29-R375 VanDerWaalsContact OE2-NH2 3.12Å; G373-R375 VanDerWaalsContact C-N 3.35Å; G373-R375 PolarHBondContact O-N 2.89Å
376	S	91.8	Very high	93.8	Very high	40 Å²	40	59.9 Å²	59.9	28%	0.28	31%	0.312	S	S	.	.			trans	-74.9	133	-176.2	179.4	0	0	0	0	112.3	P372 G373 L378 L379 P380	P372-S376 WeakPolarHBondContact CB-OG 3.17Å; P372-S376 WeakPolarHBondContact O-CB 3.26Å; G373-S376 PolarHBondContact O-N 3.08Å; S376-L378 PolarHBondContact O-N 2.99Å; S376-L378 WeakPolarHBondContact OG-CB 3.23Å; S376-L378 PolarHBondContact OG-N 3.45Å; S376-L379 PolarHBondContact O-N 3Å; S376-P380 WeakPolarHBondContact O-CD 3.47Å
377	K	91.2	Very high	93.9	Very high	180 Å²	180	63.9 Å²	63.9	78%	0.783	33%	0.33	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.3	-15.4	174.1	-59	-61.2	-175.7	179.5	0	113	L379 P380	K377-L379 VanDerWaalsContact C-N 3.29Å; K377-L379 PolarHBondContact O-N 3.36Å; K377-P380 WeakPolarHBondContact O-CD 3.33Å
378	L	95.5	Very high	94.1	Very high	98 Å²	98	66.9 Å²	66.9	51%	0.513	35%	0.348	S	S	.	.	H	α-helix	trans	-66.6	-33	176.1	-174.7	64.1	0	0	0	111.7	P372 S376 G381 L382	P372-L378 HydrophobicContact CB-CB 4.09Å; P372-L378 HydrophobicContact CB-CD2 4.01Å; P372-L378 HydrophobicContact CB-CG 4.46Å; P372-L378 HydrophobicContact CG-CB 4.02Å; P372-L378 HydrophobicContact CG-CD2 4.39Å; P372-L378 HydrophobicContact CG-CG 4.39Å; S376-L378 PolarHBondContact O-N 2.99Å; S376-L378 WeakPolarHBondContact OG-CB 3.23Å; S376-L378 PolarHBondContact OG-N 3.45Å; L378-G381 PolarHBondContact O-N 3.36Å; L378-L382 HydrophobicContact CD1-CG 4.28Å; L378-L382 HydrophobicContact CD2-CD1 4.36Å; L378-L382 HydrophobicContact CG-CD1 3.99Å; L378-L382 HydrophobicContact CG-CG 4.11Å; L378-L382 WeakPolarHBondContact O-CG 3.43Å; L378-L382 PolarHBondContact O-N 2.92Å
379	L	95.8	Very high	94.3	Very high	2 Å²	2	58.5 Å²	58.5	1%	0.01	32%	0.317	C	S	.	.	H	α-helix	trans	-61.3	-53.4	-177.3	176.4	64.8	0	0	0	112.1	L308 P372 S376 K377 G381 L382 V383 L429 V433 Y436	L308-L379 HydrophobicContact CD2-CD2 3.84Å; P372-L379 HydrophobicContact CG-CB 3.84Å; S376-L379 PolarHBondContact O-N 3Å; K377-L379 VanDerWaalsContact C-N 3.29Å; K377-L379 PolarHBondContact O-N 3.36Å; L379-G381 VanDerWaalsContact C-N 3.28Å; L379-G381 PolarHBondContact O-N 2.93Å; L379-L382 PolarHBondContact O-N 2.88Å; L379-V383 HydrophobicContact CD1-CG2 4.39Å; L379-V383 VanDerWaalsContact O-CG2 3.27Å; L379-V383 WeakPolarHBondContact O-CG2 3.35Å; L379-V383 PolarHBondContact O-N 3.5Å; L379-L429 HydrophobicContact CD1-CD2 3.97Å; L379-V433 HydrophobicContact CD1-CG2 4.29Å; L379-V433 HydrophobicContact CD2-CG2 4.01Å; L379-V433 HydrophobicContact CG-CG2 4.41Å; L379-Y436 HydrophobicContact CD2-CD2 4.15Å; L379-Y436 HydrophobicContact CD2-CE2 4.26Å
380	P	96.2	Very high	94.3	Very high	28 Å²	28	55.1 Å²	55.1	18%	0.182	30%	0.301	C	S	.	.	H	α-helix	trans	-55.4	-39.9	172.1	-26.1	31.9	0	0	0	113.9	S376 K377 V383 V384	S376-P380 WeakPolarHBondContact O-CD 3.47Å; K377-P380 WeakPolarHBondContact O-CD 3.33Å; P380-V383 PolarHBondContact O-N 3.07Å; P380-V384 WeakPolarHBondContact O-CG2 3.36Å; P380-V384 PolarHBondContact O-N 3.49Å
381	G	96.6	Very high	94.3	Very high	42 Å²	42	56.7 Å²	56.7	43%	0.433	31%	0.314	S	S	.	.	H	α-helix	trans	-61.5	-46.8	178.4	0	0	0	0	0	112.7	L378 L379 V383 V384 S385	L378-G381 PolarHBondContact O-N 3.36Å; L379-G381 VanDerWaalsContact C-N 3.28Å; L379-G381 PolarHBondContact O-N 2.93Å; G381-V383 VanDerWaalsContact C-N 3.32Å; G381-V383 PolarHBondContact O-N 3.49Å; G381-V384 PolarHBondContact O-N 3.12Å; G381-S385 WeakPolarHBondContact O-CB 3.35Å; G381-S385 PolarHBondContact O-N 3.34Å
382	L	97	Very high	94.3	Very high	66 Å²	66	55 Å²	55	35%	0.346	30%	0.302	S	S	.	.	H	α-helix	trans	-62.6	-39.8	175.7	-69.1	174.5	0	0	0	111.7	L378 L379 S385 L429	L378-L382 HydrophobicContact CD1-CG 4.28Å; L378-L382 HydrophobicContact CD2-CD1 4.36Å; L378-L382 HydrophobicContact CG-CD1 3.99Å; L378-L382 HydrophobicContact CG-CG 4.11Å; L378-L382 WeakPolarHBondContact O-CG 3.43Å; L378-L382 PolarHBondContact O-N 2.92Å; L379-L382 PolarHBondContact O-N 2.88Å; L382-S385 PolarHBondContact O-N 2.93Å; L382-S385 PolarHBondContact O-OG 3.4Å; L382-L429 HydrophobicContact CB-CD1 4.07Å; L382-L429 HydrophobicContact CB-CD2 4.18Å; L382-L429 HydrophobicContact CD1-CD2 4.17Å
383	V	97.4	Very high	94.4	Very high	0 Å²	0	54 Å²	54	0%	0	30%	0.295	C	S	.	.	H	α-helix	trans	-62.5	-50.2	176.6	170.4	0	0	0	0	111.4	C311 S314 L315 L379 P380 G381 S385 R386 L429	C311-V383 HydrophobicContact CB-CG2 4Å; S314-V383 VanDerWaalsContact CB-CG1 3.49Å; L315-V383 HydrophobicContact CD1-CG2 3.91Å; L315-V383 HydrophobicContact CD2-CB 4.39Å; L315-V383 HydrophobicContact CD2-CG1 4.13Å; L315-V383 HydrophobicContact CD2-CG2 3.89Å; L315-V383 HydrophobicContact CG-CB 4.31Å; L315-V383 HydrophobicContact CG-CG1 3.74Å; L315-V383 HydrophobicContact CG-CG2 3.75Å; L379-V383 HydrophobicContact CD1-CG2 4.39Å; L379-V383 VanDerWaalsContact O-CG2 3.27Å; L379-V383 WeakPolarHBondContact O-CG2 3.35Å; L379-V383 PolarHBondContact O-N 3.5Å; P380-V383 PolarHBondContact O-N 3.07Å; G381-V383 VanDerWaalsContact C-N 3.32Å; G381-V383 PolarHBondContact O-N 3.49Å; V383-S385 VanDerWaalsContact C-N 3.28Å; V383-S385 PolarHBondContact O-N 3.49Å; V383-R386 WeakPolarHBondContact O-CB 3.27Å; V383-R386 PolarHBondContact O-N 2.98Å; V383-R386 VanDerWaalsContact O-N 3.14Å; V383-L429 HydrophobicContact CG2-CD1 4.36Å
384	V	96.6	Very high	94.4	Very high	69 Å²	69	55.2 Å²	55.2	42%	0.418	30%	0.301	S	S	.	.	H	α-helix	trans	-64.9	-33.7	-179.7	173	0	0	0	0	111.4	F310 P380 G381 R386 F387	F310-V384 HydrophobicContact CE1-CG2 4Å; F310-V384 HydrophobicContact CZ-CG2 4.23Å; P380-V384 WeakPolarHBondContact O-CG2 3.36Å; P380-V384 PolarHBondContact O-N 3.49Å; G381-V384 PolarHBondContact O-N 3.12Å; V384-R386 PolarHBondContact O-N 2.96Å; V384-R386 VanDerWaalsContact O-N 3.09Å; V384-F387 WeakPolarHBondContact O-CB 3.41Å; V384-F387 WeakPolarHBondContact O-CD2 3.32Å; V384-F387 PolarHBondContact O-N 2.88Å; V384-F387 VanDerWaalsContact O-N 3.1Å
385	S	96.6	Very high	94.5	Very high	63 Å²	63	55.3 Å²	55.3	44%	0.441	30%	0.299	S	S	.	.	H	α-helix	trans	-58.9	-23.9	176	78.9	0	0	0	0	113.6	G381 L382 V383 F387 C388	G381-S385 WeakPolarHBondContact O-CB 3.35Å; G381-S385 PolarHBondContact O-N 3.34Å; L382-S385 PolarHBondContact O-N 2.93Å; L382-S385 PolarHBondContact O-OG 3.4Å; V383-S385 VanDerWaalsContact C-N 3.28Å; V383-S385 PolarHBondContact O-N 3.49Å; S385-F387 PolarHBondContact O-N 3.43Å; S385-C388 VanDerWaalsContact O-CB 3.28Å; S385-C388 WeakPolarHBondContact O-CB 3.5Å; S385-C388 PolarHBondContact O-N 2.94Å; S385-C388 VanDerWaalsContact O-N 3.08Å; S385-C388 PolarHBondContact O-SG 2.88Å
386	R	97.5	Very high	94.7	Very high	7 Å²	7	46.5 Å²	46.5	3%	0.026	27%	0.266	C	S	.	.	G	3₁₀ helix	trans	-66.3	-20.5	178.4	-66.7	-173.2	65.6	-160.1	-8.9	113.3	V318 T319 V383 V384 C388 L389 L422 S425 N426	V318-R386 HydrophobicContact CG1-CB 4.17Å; V318-R386 WeakPolarHBondContact CG1-O 3.47Å; T319-R386 PolarHBondContact OG1-NH2 3.49Å; V383-R386 WeakPolarHBondContact O-CB 3.27Å; V383-R386 PolarHBondContact O-N 2.98Å; V383-R386 VanDerWaalsContact O-N 3.14Å; V384-R386 PolarHBondContact O-N 2.96Å; V384-R386 VanDerWaalsContact O-N 3.09Å; R386-C388 PolarHBondContact O-N 3.38Å; R386-C388 VanDerWaalsContact O-N 3.16Å; R386-L389 HydrophobicContact CB-CD1 4.39Å; R386-L389 VanDerWaalsContact O-CB 3.27Å; R386-L389 WeakPolarHBondContact O-CB 3.48Å; R386-L389 WeakPolarHBondContact O-CG 3.43Å; R386-L389 PolarHBondContact O-N 2.96Å; R386-L422 PolarHBondContact NH2-O 3.39Å; R386-S425 PolarHBondContact NE-OG 3.3Å; R386-N426 PolarHBondContact NH1-OD1 3.35Å
387	F	97	Very high	94.7	Very high	83 Å²	83	45.7 Å²	45.7	36%	0.364	26%	0.259	S	S	.	.	G	3₁₀ helix	trans	-59.4	-24.5	172.6	-80.2	-94.2	0	0	0	112.3	F317 V318 V384 S385 L389 V390 P391	F317-F387 AromaticContact CD1-CE1 3.81Å; F317-F387 HydrophobicContact CD1-CE1 3.81Å; F317-F387 AromaticContact CD1-CZ 3.91Å; F317-F387 HydrophobicContact CD1-CZ 3.91Å; F317-F387 AromaticContact CE1-CE1 3.8Å; F317-F387 HydrophobicContact CE1-CE1 3.8Å; F317-F387 HydrophobicContact CE1-CZ 4.32Å; V318-F387 HydrophobicContact CG2-CD1 3.88Å; V318-F387 HydrophobicContact CG2-CD2 3.63Å; V318-F387 HydrophobicContact CG2-CE1 3.86Å; V318-F387 HydrophobicContact CG2-CE2 3.61Å; V318-F387 HydrophobicContact CG2-CG 3.78Å; V318-F387 HydrophobicContact CG2-CZ 3.72Å; V384-F387 WeakPolarHBondContact O-CB 3.41Å; V384-F387 WeakPolarHBondContact O-CD2 3.32Å; V384-F387 PolarHBondContact O-N 2.88Å; V384-F387 VanDerWaalsContact O-N 3.1Å; S385-F387 PolarHBondContact O-N 3.43Å; F387-L389 PolarHBondContact O-N 3.43Å; F387-V390 WeakPolarHBondContact O-CB 3.29Å; F387-V390 PolarHBondContact O-N 2.95Å; F387-P391 VanDerWaalsContact O-CD 3.3Å; F387-P391 WeakPolarHBondContact O-CD 3.27Å
388	C	96.6	Very high	94.4	Very high	85 Å²	85	37.5 Å²	37.5	57%	0.574	22%	0.223	S	C	*	.	G	3₁₀ helix	trans	-63.5	-19.4	172.8	-62.1	0	0	0	0	113.4	S385 R386 P391 L392	S385-C388 VanDerWaalsContact O-CB 3.28Å; S385-C388 WeakPolarHBondContact O-CB 3.5Å; S385-C388 PolarHBondContact O-N 2.94Å; S385-C388 VanDerWaalsContact O-N 3.08Å; S385-C388 PolarHBondContact O-SG 2.88Å; R386-C388 PolarHBondContact O-N 3.38Å; R386-C388 VanDerWaalsContact O-N 3.16Å; C388-P391 WeakPolarHBondContact O-CD 3.34Å; C388-P391 WeakPolarHBondContact O-CG 3.46Å; C388-L392 WeakPolarHBondContact O-CG 3.24Å
389	L	96.4	Very high	93.9	Very high	10 Å²	10	36 Å²	36	5%	0.052	21%	0.213	C	C	.	.	H	α-helix	trans	-70.1	-32.4	175.8	-63	172.9	0	0	0	111.9	I322 R386 F387 L392 F393 L421 L422	I322-L389 HydrophobicContact CD1-CB 3.96Å; R386-L389 HydrophobicContact CB-CD1 4.39Å; R386-L389 VanDerWaalsContact O-CB 3.27Å; R386-L389 WeakPolarHBondContact O-CB 3.48Å; R386-L389 WeakPolarHBondContact O-CG 3.43Å; R386-L389 PolarHBondContact O-N 2.96Å; F387-L389 PolarHBondContact O-N 3.43Å; L389-L392 HydrophobicContact CD2-CD1 4.22Å; L389-L392 WeakPolarHBondContact O-CB 3.32Å; L389-L392 PolarHBondContact O-N 3.48Å; L389-L392 VanDerWaalsContact O-N 3.1Å; L389-F393 HydrophobicContact CB-CD2 4.41Å; L389-F393 HydrophobicContact CB-CE2 4.48Å; L389-F393 WeakPolarHBondContact O-CD2 3.33Å; L389-F393 PolarHBondContact O-N 2.82Å; L389-L421 HydrophobicContact CD2-CD2 3.73Å; L389-L421 HydrophobicContact CD2-CG 4.09Å; L389-L422 HydrophobicContact CD1-CB 4.19Å; L389-L422 HydrophobicContact CD1-CD1 3.53Å; L389-L422 HydrophobicContact CD1-CG 4.49Å
390	V	94.3	Very high	93.3	Very high	21 Å²	21	40.2 Å²	40.2	13%	0.127	24%	0.24	C	C	.	.	H	α-helix	trans	-54.7	-55.6	-178.8	178	0	0	0	0	112.5	V318 F321 I322 F387 L392 F393 L394	V318-V390 HydrophobicContact CG1-CG2 4.33Å; F321-V390 HydrophobicContact CD1-CG1 3.81Å; F321-V390 HydrophobicContact CD1-CG2 4.05Å; F321-V390 HydrophobicContact CE1-CG1 3.5Å; F321-V390 VanDerWaalsContact CE1-CG1 3.5Å; I322-V390 HydrophobicContact CD1-CG2 4Å; I322-V390 HydrophobicContact CG1-CG2 4.09Å; F387-V390 WeakPolarHBondContact O-CB 3.29Å; F387-V390 PolarHBondContact O-N 2.95Å; V390-L392 VanDerWaalsContact C-N 3.28Å; V390-L392 PolarHBondContact O-N 3.5Å; V390-F393 PolarHBondContact O-N 3.28Å; V390-L394 HydrophobicContact CG1-CD1 4.1Å; V390-L394 PolarHBondContact O-N 3.5Å; V390-L394 VanDerWaalsContact O-N 3.11Å
391	P	92.4	Very high	92.2	Very high	63 Å²	63	40.9 Å²	40.9	41%	0.409	24%	0.24	S	C	.	.	H	α-helix	trans	-64.4	-31.9	177.3	25.3	-34.6	0	0	0	112.6	F387 C388 F393 L394 L395	F387-P391 VanDerWaalsContact O-CD 3.3Å; F387-P391 WeakPolarHBondContact O-CD 3.27Å; C388-P391 WeakPolarHBondContact O-CD 3.34Å; C388-P391 WeakPolarHBondContact O-CG 3.46Å; P391-F393 PolarHBondContact O-N 3.22Å; P391-L394 PolarHBondContact O-N 2.95Å; P391-L395 VanDerWaalsContact O-CB 3.27Å; P391-L395 WeakPolarHBondContact O-CB 3.41Å; P391-L395 WeakPolarHBondContact O-CD1 3.25Å; P391-L395 WeakPolarHBondContact O-CG 3.41Å; P391-L395 PolarHBondContact O-N 2.86Å
392	L	94.2	Very high	91.1	Very high	50 Å²	50	42.2 Å²	42.2	26%	0.262	24%	0.242	S	C	.	.	H	α-helix	trans	-61.5	-43.5	176.9	-66.6	175.5	0	0	0	111.6	C388 L389 V390 L395 C396 F409 F418	C388-L392 WeakPolarHBondContact O-CG 3.24Å; L389-L392 HydrophobicContact CD2-CD1 4.22Å; L389-L392 WeakPolarHBondContact O-CB 3.32Å; L389-L392 PolarHBondContact O-N 3.48Å; L389-L392 VanDerWaalsContact O-N 3.1Å; V390-L392 VanDerWaalsContact C-N 3.28Å; V390-L392 PolarHBondContact O-N 3.5Å; L392-L395 PolarHBondContact O-N 2.76Å; L392-C396 PolarHBondContact O-N 2.66Å; L392-C396 PolarHBondContact O-SG 2.69Å; L392-C396 VanDerWaalsContact O-SG 3.37Å; L392-F409 HydrophobicContact CD2-CE2 3.61Å; L392-F409 HydrophobicContact CD2-CZ 3.64Å; L392-F418 HydrophobicContact CB-CD2 3.95Å; L392-F418 HydrophobicContact CB-CE1 4.48Å; L392-F418 HydrophobicContact CB-CE2 3.78Å; L392-F418 HydrophobicContact CB-CG 4.4Å; L392-F418 HydrophobicContact CB-CZ 4.07Å; L392-F418 HydrophobicContact CD1-CD1 4.42Å; L392-F418 HydrophobicContact CD1-CE1 4.17Å; L392-F418 HydrophobicContact CD1-CZ 4.4Å; L392-F418 HydrophobicContact CD2-CZ 4.11Å; L392-F418 HydrophobicContact CG-CZ 4.42Å
393	F	93.5	Very high	90	Very high	0 Å²	0	46 Å²	46	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-67.7	-42.1	175.7	-84.5	-91	0	0	0	112.7	I322 I326 I330 L389 V390 P391 L395 C396 F418 L422	I322-F393 HydrophobicContact CD1-CD2 4.02Å; I322-F393 HydrophobicContact CD1-CE2 4.35Å; I322-F393 HydrophobicContact CG2-CB 4.25Å; I322-F393 HydrophobicContact CG2-CD1 3.76Å; I322-F393 HydrophobicContact CG2-CD2 3.79Å; I322-F393 HydrophobicContact CG2-CE1 3.97Å; I322-F393 HydrophobicContact CG2-CE2 3.99Å; I322-F393 HydrophobicContact CG2-CG 3.67Å; I322-F393 HydrophobicContact CG2-CZ 4.08Å; I326-F393 HydrophobicContact CG2-CB 4.02Å; I330-F393 HydrophobicContact CD1-CD1 3.67Å; I330-F393 HydrophobicContact CD1-CE1 4.45Å; L389-F393 HydrophobicContact CB-CD2 4.41Å; L389-F393 HydrophobicContact CB-CE2 4.48Å; L389-F393 WeakPolarHBondContact O-CD2 3.33Å; L389-F393 PolarHBondContact O-N 2.82Å; V390-F393 PolarHBondContact O-N 3.28Å; P391-F393 PolarHBondContact O-N 3.22Å; F393-L395 PolarHBondContact O-N 3.02Å; F393-C396 WeakPolarHBondContact O-CB 3.48Å; F393-C396 PolarHBondContact O-N 3.48Å; F393-F418 HydrophobicContact CD2-CB 4.18Å; F393-F418 HydrophobicContact CE1-CB 4.27Å; F393-F418 HydrophobicContact CE2-CB 3.59Å; F393-F418 VanDerWaalsContact CZ-C 3.48Å; F393-F418 HydrophobicContact CZ-CB 3.65Å; F393-L422 HydrophobicContact CE2-CB 4.26Å; F393-L422 HydrophobicContact CE2-CD2 4.18Å; F393-L422 HydrophobicContact CZ-CB 4.32Å; F393-L422 HydrophobicContact CZ-CD2 4.07Å
394	L	89.8	Confident	88.9	Confident	27 Å²	27	48.7 Å²	48.7	14%	0.141	27%	0.272	C	S	.	.	H	α-helix	trans	-63.4	-26.8	176.9	-70	171.5	0	0	0	113	I326 V390 P391 R401 L471 I475	I326-L394 HydrophobicContact CD1-CD2 4.03Å; I326-L394 HydrophobicContact CD1-CG 4.38Å; I326-L394 HydrophobicContact CG1-CD2 4.34Å; I326-L394 HydrophobicContact CG2-CD2 3.91Å; I326-L394 HydrophobicContact CG2-CG 4.41Å; V390-L394 HydrophobicContact CG1-CD1 4.1Å; V390-L394 PolarHBondContact O-N 3.5Å; V390-L394 VanDerWaalsContact O-N 3.11Å; P391-L394 PolarHBondContact O-N 2.95Å; L394-R401 PolarHBondContact O-NH2 2.74Å; L394-R401 VanDerWaalsContact O-NH2 3.09Å; L394-L471 HydrophobicContact CD2-CD2 4.1Å; L394-I475 HydrophobicContact CD2-CD1 4.23Å
395	L	91.2	Very high	87.7	Confident	42 Å²	42	51.3 Å²	51.3	22%	0.22	29%	0.288	C	S	.	.	T	Hydrogen-bonded Turn	trans	-89	-6.6	179.4	-69.8	174.2	0	0	0	114.2	P391 L392 F393 L408 F409	P391-L395 VanDerWaalsContact O-CB 3.27Å; P391-L395 WeakPolarHBondContact O-CB 3.41Å; P391-L395 WeakPolarHBondContact O-CD1 3.25Å; P391-L395 WeakPolarHBondContact O-CG 3.41Å; P391-L395 PolarHBondContact O-N 2.86Å; L392-L395 PolarHBondContact O-N 2.76Å; F393-L395 PolarHBondContact O-N 3.02Å; L395-L408 HydrophobicContact CB-CB 4.24Å; L395-L408 HydrophobicContact CD1-CD1 3.75Å; L395-L408 HydrophobicContact CD2-CD1 3.97Å; L395-L408 HydrophobicContact CG-CD1 4.32Å; L395-L408 PolarHBondContact O-N 3.44Å; L395-F409 HydrophobicContact CB-CD2 3.79Å; L395-F409 HydrophobicContact CB-CE2 3.94Å; L395-F409 HydrophobicContact CD1-CE2 4.47Å; L395-F409 PolarHBondContact O-N 3.28Å; L395-F409 VanDerWaalsContact O-N 3.07Å
396	C	92.1	Very high	86.9	Confident	0 Å²	0	55 Å²	55	0%	0	30%	0.296	C	S	.	.	B	Isolated β-bridge	trans	-70.3	177.6	166.3	-71.6	0	0	0	0	111.6	I330 L392 F393 Y398 R401 F418	I330-C396 HydrophobicContact CD1-CB 3.81Å; I330-C396 HydrophobicContact CG1-CB 4.24Å; I330-C396 HydrophobicContact CG2-CB 4.17Å; L392-C396 PolarHBondContact O-N 2.66Å; L392-C396 PolarHBondContact O-SG 2.69Å; L392-C396 VanDerWaalsContact O-SG 3.37Å; F393-C396 WeakPolarHBondContact O-CB 3.48Å; F393-C396 PolarHBondContact O-N 3.48Å; C396-Y398 PolarHBondContact O-N 2.9Å; C396-R401 PolarHBondContact O-NH2 3.42Å; C396-F418 VanDerWaalsContact SG-CD2 3.55Å; C396-F418 VanDerWaalsContact SG-CE2 3.59Å
397	N	90	Very high	86.3	Confident	24 Å²	24	56.2 Å²	56.2	13%	0.128	30%	0.304	C	S	.	.	S	Bend	trans	-70.4	57.1	178.5	-169.9	30.2	0	0	0	114.9	I330 Q331 Q399 V407	I330-N397 WeakPolarHBondContact CA-O 3.36Å; Q331-N397 PolarHBondContact N-O 3.03Å; Q331-N397 PolarHBondContact O-ND2 3.3Å; N397-Q399 PolarHBondContact OD1-NE2 2.86Å; N397-V407 HydrophobicContact CB-CG1 4.29Å
398	Y	86.5	Confident	85.9	Confident	8 Å²	8	56.9 Å²	56.9	3%	0.031	31%	0.311	C	S	.	.	B	Isolated β-bridge	trans	-61.6	138.8	169.5	-175.4	-87.1	0	0	0	111.1	I326 N329 C396 P400 R401 I475	I326-Y398 HydrophobicContact CG2-CD2 4.16Å; I326-Y398 HydrophobicContact CG2-CE2 4.32Å; I326-Y398 WeakPolarHBondContact O-CD2 3.38Å; N329-Y398 HydrophobicContact CB-CD2 3.57Å; N329-Y398 HydrophobicContact CB-CE1 4.43Å; N329-Y398 HydrophobicContact CB-CE2 3.2Å; N329-Y398 HydrophobicContact CB-CG 4.32Å; N329-Y398 PolarHBondContact ND2-OH 3.44Å; N329-Y398 CarbonylContact O-C 3.55Å; C396-Y398 PolarHBondContact O-N 2.9Å; Y398-P400 WeakPolarHBondContact CD1-O 3.41Å; Y398-P400 VanDerWaalsContact CE1-O 3.3Å; Y398-P400 WeakPolarHBondContact CE1-O 3.12Å; Y398-R401 VanDerWaalsContact O-CD 3.29Å; Y398-R401 WeakPolarHBondContact O-CD 3.48Å; Y398-R401 WeakPolarHBondContact O-CG 3.32Å; Y398-R401 PolarHBondContact O-NE 2.79Å; Y398-I475 HydrophobicContact CE1-CG2 4.32Å
399	Q	84.5	Confident	85.6	Confident	65 Å²	65	55 Å²	55	30%	0.304	29%	0.293	S	S	.	.	S	Bend	trans	-143.5	142.3	178.5	-63.7	-64.5	-19.5	0	0	110.1	N329 Q331 N397	N329-Q399 WeakPolarHBondContact CB-O 3.41Å; N329-Q399 PolarHBondContact O-N 3.31Å; N329-Q399 PolarHBondContact OD1-O 3.07Å; Q331-Q399 HydrophobicContact CB-CG 4.4Å; Q331-Q399 HydrophobicContact CG-CB 4.17Å; Q331-Q399 HydrophobicContact CG-CG 4.23Å; N397-Q399 PolarHBondContact OD1-NE2 2.86Å
400	P	82.3	Confident	84.9	Confident	91 Å²	91	60 Å²	60	59%	0.591	32%	0.317	S	S	*	.	S	Bend	cis	-75	159.2	-2.6	31.6	-34.5	0	0	0	112.7	Y398	Y398-P400 WeakPolarHBondContact CD1-O 3.41Å; Y398-P400 VanDerWaalsContact CE1-O 3.3Å; Y398-P400 WeakPolarHBondContact CE1-O 3.12Å
401	R	73.5	Confident	84.8	Confident	43 Å²	43	61.5 Å²	61.5	16%	0.162	33%	0.328	C	S	.	.			trans	-116.2	92.8	177.7	-76.9	174.3	171	-93.4	-5.5	110.4	L394 C396 Y398 L404 K406 V407	L394-R401 PolarHBondContact O-NH2 2.74Å; L394-R401 VanDerWaalsContact O-NH2 3.09Å; C396-R401 PolarHBondContact O-NH2 3.42Å; Y398-R401 VanDerWaalsContact O-CD 3.29Å; Y398-R401 WeakPolarHBondContact O-CD 3.48Å; Y398-R401 WeakPolarHBondContact O-CG 3.32Å; Y398-R401 PolarHBondContact O-NE 2.79Å; R401-L404 VanDerWaalsContact CB-O 3.31Å; R401-L404 WeakPolarHBondContact CB-O 3.34Å; R401-L404 WeakPolarHBondContact CD-O 3.39Å; R401-L404 WeakPolarHBondContact CG-O 3.39Å; R401-L404 PolarHBondContact NH1-O 2.98Å; R401-K406 PolarHBondContact NH1-O 3.41Å; R401-V407 VanDerWaalsContact CZ-CG2 3.48Å
402	S	73.4	Confident	84.8	Confident	70 Å²	70	60 Å²	60	49%	0.49	32%	0.317	S	S	.	.	S	Bend	trans	-82.4	-48.2	172.9	72.3	0	0	0	0	111.4	I475	S402-I475 VanDerWaalsContact CB-O 3.31Å; S402-I475 WeakPolarHBondContact CB-O 3.3Å; S402-I475 PolarHBondContact OG-O 3.33Å
403	H	74.4	Confident	84.8	Confident	146 Å²	146	62.1 Å²	62.1	68%	0.676	33%	0.327	S	S	*	.	S	Bend	trans	-110.1	-30.5	-173	-64.3	-61	0	0	0	113.7	T405 F474	H403-T405 PolarHBondContact O-N 3.47Å; H403-F474 PolarHBondContact CD2-O 3.26Å
404	L	74.2	Confident	84.9	Confident	56 Å²	56	66.6 Å²	66.6	29%	0.293	34%	0.344	S	S	.	.			trans	-92	86.7	177.9	-90	144.2	0	0	0	110.2	R401 I475	R401-L404 VanDerWaalsContact CB-O 3.31Å; R401-L404 WeakPolarHBondContact CB-O 3.34Å; R401-L404 WeakPolarHBondContact CD-O 3.39Å; R401-L404 WeakPolarHBondContact CG-O 3.39Å; R401-L404 PolarHBondContact NH1-O 2.98Å; L404-I475 HydrophobicContact CD1-CD1 4.05Å; L404-I475 HydrophobicContact CD1-CG2 4.22Å
405	T	72.1	Confident	85.1	Confident	124 Å²	124	65.6 Å²	65.6	76%	0.761	34%	0.34	S	S	*	.			trans	-80	-21.3	-176	52.9	0	0	0	0	114.3	H403	H403-T405 PolarHBondContact O-N 3.47Å
406	K	79.8	Confident	85.3	Confident	141 Å²	141	65.9 Å²	65.9	61%	0.613	34%	0.343	S	S	*	.			trans	-93.3	119.7	-174.9	-166.1	171.8	-177.8	176	0	112.3	R401	R401-K406 PolarHBondContact NH1-O 3.41Å
407	V	85.1	Confident	85.5	Confident	32 Å²	32	70.4 Å²	70.4	19%	0.194	37%	0.367	C	S	.	.			trans	-96.4	107.5	166.6	-175.4	0	0	0	0	108	N397 R401 Q410	N397-V407 HydrophobicContact CB-CG1 4.29Å; R401-V407 VanDerWaalsContact CZ-CG2 3.48Å; V407-Q410 HydrophobicContact CB-CG 4.23Å; V407-Q410 HydrophobicContact CG1-CB 4.48Å; V407-Q410 HydrophobicContact CG1-CG 3.75Å
408	L	88.3	Confident	85.9	Confident	97 Å²	97	70.4 Å²	70.4	51%	0.508	37%	0.366	S	S	.	.	S	Bend	trans	-82.9	-39.3	175.8	-91.4	160.5	0	0	0	111	L395	L395-L408 HydrophobicContact CB-CB 4.24Å; L395-L408 HydrophobicContact CD1-CD1 3.75Å; L395-L408 HydrophobicContact CD2-CD1 3.97Å; L395-L408 HydrophobicContact CG-CD1 4.32Å; L395-L408 PolarHBondContact O-N 3.44Å
409	F	88.9	Confident	86.4	Confident	45 Å²	45	70.1 Å²	70.1	20%	0.197	37%	0.365	C	S	.	.	B	Isolated β-bridge	trans	-104.3	83.3	-178.2	-57.9	-67.3	0	0	0	110	L392 L395 Y414 F418	L392-F409 HydrophobicContact CD2-CE2 3.61Å; L392-F409 HydrophobicContact CD2-CZ 3.64Å; L395-F409 HydrophobicContact CB-CD2 3.79Å; L395-F409 HydrophobicContact CB-CE2 3.94Å; L395-F409 HydrophobicContact CD1-CE2 4.47Å; L395-F409 PolarHBondContact O-N 3.28Å; L395-F409 VanDerWaalsContact O-N 3.07Å; F409-Y414 HydrophobicContact CB-CD2 3.7Å; F409-Y414 HydrophobicContact CB-CE2 4.46Å; F409-Y414 HydrophobicContact CB-CG 3.74Å; F409-Y414 AromaticContact CD1-CD1 3.75Å; F409-Y414 HydrophobicContact CD1-CD1 3.75Å; F409-Y414 HydrophobicContact CD1-CD2 4.11Å; F409-Y414 AromaticContact CD1-CE1 3.99Å; F409-Y414 HydrophobicContact CD1-CE1 3.99Å; F409-Y414 HydrophobicContact CD1-CE2 4.33Å; F409-Y414 AromaticContact CD1-CG 3.82Å; F409-Y414 HydrophobicContact CD1-CG 3.82Å; F409-Y414 HydrophobicContact CE1-CD1 4.47Å; F409-Y414 HydrophobicContact CG-CD1 4.47Å; F409-Y414 HydrophobicContact CG-CD2 4.39Å; F409-Y414 HydrophobicContact CG-CG 4.14Å; F409-F418 HydrophobicContact CB-CE2 4.45Å; F409-F418 HydrophobicContact CD1-CE2 4.35Å; F409-F418 HydrophobicContact CD1-CZ 4.06Å; F409-F418 AromaticContact CD2-CE2 3.75Å; F409-F418 HydrophobicContact CD2-CE2 3.75Å; F409-F418 HydrophobicContact CD2-CZ 4.08Å; F409-F418 AromaticContact CE1-CZ 4Å; F409-F418 HydrophobicContact CE1-CZ 4Å; F409-F418 HydrophobicContact CE2-CE2 4.04Å; F409-F418 HydrophobicContact CE2-CZ 4.03Å; F409-F418 AromaticContact CG-CE2 3.93Å; F409-F418 HydrophobicContact CG-CE2 3.93Å; F409-F418 HydrophobicContact CG-CZ 4.1Å; F409-F418 HydrophobicContact CZ-CE2 4.45Å; F409-F418 AromaticContact CZ-CZ 3.99Å; F409-F418 HydrophobicContact CZ-CZ 3.99Å
410	Q	83.7	Confident	87	Confident	116 Å²	116	68.7 Å²	68.7	54%	0.542	36%	0.362	S	S	.	.			trans	-72.2	-52.7	-176.3	-74.3	-170.7	4.2	0	0	111.8	M333 V407	M333-Q410 HydrophobicContact CE-CB 3.72Å; M333-Q410 WeakPolarHBondContact CG-O 3.37Å; M333-Q410 HydrophobicContact SD-CB 3.57Å; M333-Q410 VanDerWaalsContact SD-CB 3.57Å; M333-Q410 HydrophobicContact SD-CG 4.33Å; V407-Q410 HydrophobicContact CB-CG 4.23Å; V407-Q410 HydrophobicContact CG1-CB 4.48Å; V407-Q410 HydrophobicContact CG1-CG 3.75Å
411	S	92.1	Very high	87.7	Confident	52 Å²	52	68.8 Å²	68.8	36%	0.364	36%	0.357	S	S	.	.	S	Bend	trans	-59.3	139	-175.3	-178.5	0	0	0	0	114.3	I413 Y414 P415	S411-I413 PolarHBondContact O-N 2.89Å; S411-I413 WeakPolarHBondContact OG-CG2 3.34Å; S411-I413 PolarHBondContact OG-N 3.02Å; S411-Y414 VanDerWaalsContact O-CD2 3.3Å; S411-Y414 WeakPolarHBondContact O-CD2 3.11Å; S411-Y414 PolarHBondContact O-N 3.06Å; S411-P415 WeakPolarHBondContact O-CD 3.27Å
412	D	92.1	Very high	88.9	Confident	32 Å²	32	66.8 Å²	66.8	17%	0.171	35%	0.349	C	S	.	.	T	Hydrogen-bonded Turn	trans	-57.6	-18	175.6	-64.6	-0.1	0	0	0	113	S332 M333 H334 F346 Y414 P415 V416	S332-D412 WeakPolarHBondContact CA-OD1 3.49Å; S332-D412 WeakPolarHBondContact CB-OD2 3.44Å; S332-D412 PolarHBondContact OG-OD2 3.36Å; M333-D412 WeakPolarHBondContact CG-OD1 3.3Å; M333-D412 PolarHBondContact N-OD1 3.32Å; H334-D412 IonicContact ND1-OD2 3.12Å; F346-D412 HydrophobicContact CE2-CB 4.06Å; F346-D412 HydrophobicContact CZ-CB 4.44Å; D412-Y414 VanDerWaalsContact C-N 3.32Å; D412-Y414 PolarHBondContact O-N 2.94Å; D412-P415 WeakPolarHBondContact O-CD 3.32Å; D412-P415 VanDerWaalsContact O-CG 3.31Å; D412-P415 WeakPolarHBondContact O-CG 3.36Å; D412-V416 WeakPolarHBondContact O-CG2 3.49Å
413	I	94.4	Very high	90.1	Very high	94 Å²	94	63.4 Å²	63.4	48%	0.482	33%	0.326	S	S	.	.	H	α-helix	trans	-67.6	-30.7	176	-157.8	165.8	0	0	0	112.8	S411 V416 L417	S411-I413 PolarHBondContact O-N 2.89Å; S411-I413 WeakPolarHBondContact OG-CG2 3.34Å; S411-I413 PolarHBondContact OG-N 3.02Å; I413-V416 WeakPolarHBondContact O-CB 3.43Å; I413-V416 PolarHBondContact O-N 3.18Å; I413-L417 HydrophobicContact CG1-CD1 4.19Å; I413-L417 HydrophobicContact CG1-CG 4.36Å; I413-L417 VanDerWaalsContact O-CG 3.28Å; I413-L417 WeakPolarHBondContact O-CG 3.22Å; I413-L417 PolarHBondContact O-N 3.5Å
414	Y	94.7	Very high	91.2	Very high	93 Å²	93	60.2 Å²	60.2	37%	0.365	31%	0.313	S	S	.	.	H	α-helix	trans	-67.3	-51.8	-178.1	-64.8	-65.3	0	0	0	113.1	F409 S411 D412 V416 L417 F418	F409-Y414 HydrophobicContact CB-CD2 3.7Å; F409-Y414 HydrophobicContact CB-CE2 4.46Å; F409-Y414 HydrophobicContact CB-CG 3.74Å; F409-Y414 AromaticContact CD1-CD1 3.75Å; F409-Y414 HydrophobicContact CD1-CD1 3.75Å; F409-Y414 HydrophobicContact CD1-CD2 4.11Å; F409-Y414 AromaticContact CD1-CE1 3.99Å; F409-Y414 HydrophobicContact CD1-CE1 3.99Å; F409-Y414 HydrophobicContact CD1-CE2 4.33Å; F409-Y414 AromaticContact CD1-CG 3.82Å; F409-Y414 HydrophobicContact CD1-CG 3.82Å; F409-Y414 HydrophobicContact CE1-CD1 4.47Å; F409-Y414 HydrophobicContact CG-CD1 4.47Å; F409-Y414 HydrophobicContact CG-CD2 4.39Å; F409-Y414 HydrophobicContact CG-CG 4.14Å; S411-Y414 VanDerWaalsContact O-CD2 3.3Å; S411-Y414 WeakPolarHBondContact O-CD2 3.11Å; S411-Y414 PolarHBondContact O-N 3.06Å; D412-Y414 VanDerWaalsContact C-N 3.32Å; D412-Y414 PolarHBondContact O-N 2.94Å; Y414-V416 PolarHBondContact O-N 2.92Å; Y414-L417 PolarHBondContact O-N 3.27Å; Y414-L417 VanDerWaalsContact O-N 3.17Å; Y414-F418 HydrophobicContact CD1-CZ 4.43Å; Y414-F418 WeakPolarHBondContact O-CD2 3.18Å; Y414-F418 VanDerWaalsContact O-CG 3.23Å; Y414-F418 WeakPolarHBondContact O-CG 3.2Å; Y414-F418 PolarHBondContact O-N 2.87Å
415	P	93.6	Very high	92.3	Very high	7 Å²	7	58.6 Å²	58.6	5%	0.045	31%	0.306	C	S	.	.	H	α-helix	trans	-60.5	-34.4	175.4	22.7	-32.5	0	0	0	112.1	I330 F346 S411 D412 F418 T419	I330-P415 HydrophobicContact CD1-CB 4.46Å; I330-P415 HydrophobicContact CG2-CB 4Å; I330-P415 HydrophobicContact CG2-CG 4.14Å; F346-P415 HydrophobicContact CZ-CG 4.34Å; S411-P415 WeakPolarHBondContact O-CD 3.27Å; D412-P415 WeakPolarHBondContact O-CD 3.32Å; D412-P415 VanDerWaalsContact O-CG 3.31Å; D412-P415 WeakPolarHBondContact O-CG 3.36Å; P415-F418 PolarHBondContact O-N 2.53Å; P415-T419 WeakPolarHBondContact O-CB 3.48Å; P415-T419 PolarHBondContact O-N 2.89Å; P415-T419 PolarHBondContact O-OG1 3.08Å
416	V	95.6	Very high	93.5	Very high	48 Å²	48	52.9 Å²	52.9	29%	0.291	27%	0.271	S	S	.	.	H	α-helix	trans	-59.7	-50.9	173.1	169.1	0	0	0	0	111.2	T350 L354 D412 I413 Y414 F418 T419 C420	T350-V416 HydrophobicContact CG2-CG2 3.79Å; L354-V416 HydrophobicContact CD2-CB 4.14Å; L354-V416 HydrophobicContact CD2-CG1 3.69Å; L354-V416 HydrophobicContact CD2-CG2 4.37Å; L354-V416 WeakPolarHBondContact CD2-O 3.35Å; D412-V416 WeakPolarHBondContact O-CG2 3.49Å; I413-V416 WeakPolarHBondContact O-CB 3.43Å; I413-V416 PolarHBondContact O-N 3.18Å; Y414-V416 PolarHBondContact O-N 2.92Å; V416-F418 PolarHBondContact O-N 2.71Å; V416-T419 PolarHBondContact O-N 3.48Å; V416-C420 PolarHBondContact O-N 2.94Å; V416-C420 PolarHBondContact O-SG 3.44Å; V416-C420 VanDerWaalsContact O-SG 3.37Å
417	L	96.9	Very high	94.4	Very high	95 Å²	95	46.1 Å²	46.1	50%	0.497	24%	0.242	S	C	.	.	H	α-helix	trans	-63.5	-42.1	179.4	-71.2	171.3	0	0	0	112.2	I413 Y414 C420 L421	I413-L417 HydrophobicContact CG1-CD1 4.19Å; I413-L417 HydrophobicContact CG1-CG 4.36Å; I413-L417 VanDerWaalsContact O-CG 3.28Å; I413-L417 WeakPolarHBondContact O-CG 3.22Å; I413-L417 PolarHBondContact O-N 3.5Å; Y414-L417 PolarHBondContact O-N 3.27Å; Y414-L417 VanDerWaalsContact O-N 3.17Å; L417-C420 PolarHBondContact O-N 2.9Å; L417-L421 WeakPolarHBondContact O-CB 3.49Å; L417-L421 PolarHBondContact O-N 2.98Å
418	F	97	Very high	95	Very high	24 Å²	24	46.7 Å²	46.7	11%	0.105	24%	0.241	C	C	.	.	H	α-helix	trans	-68.1	-37.5	178.8	-59.5	-22.5	0	0	0	111.9	L392 F393 C396 F409 Y414 P415 V416 L421 L422	L392-F418 HydrophobicContact CB-CD2 3.95Å; L392-F418 HydrophobicContact CB-CE1 4.48Å; L392-F418 HydrophobicContact CB-CE2 3.78Å; L392-F418 HydrophobicContact CB-CG 4.4Å; L392-F418 HydrophobicContact CB-CZ 4.07Å; L392-F418 HydrophobicContact CD1-CD1 4.42Å; L392-F418 HydrophobicContact CD1-CE1 4.17Å; L392-F418 HydrophobicContact CD1-CZ 4.4Å; L392-F418 HydrophobicContact CD2-CZ 4.11Å; L392-F418 HydrophobicContact CG-CZ 4.42Å; F393-F418 HydrophobicContact CD2-CB 4.18Å; F393-F418 HydrophobicContact CE1-CB 4.27Å; F393-F418 HydrophobicContact CE2-CB 3.59Å; F393-F418 VanDerWaalsContact CZ-C 3.48Å; F393-F418 HydrophobicContact CZ-CB 3.65Å; C396-F418 VanDerWaalsContact SG-CD2 3.55Å; C396-F418 VanDerWaalsContact SG-CE2 3.59Å; F409-F418 HydrophobicContact CB-CE2 4.45Å; F409-F418 HydrophobicContact CD1-CE2 4.35Å; F409-F418 HydrophobicContact CD1-CZ 4.06Å; F409-F418 AromaticContact CD2-CE2 3.75Å; F409-F418 HydrophobicContact CD2-CE2 3.75Å; F409-F418 HydrophobicContact CD2-CZ 4.08Å; F409-F418 AromaticContact CE1-CZ 4Å; F409-F418 HydrophobicContact CE1-CZ 4Å; F409-F418 HydrophobicContact CE2-CE2 4.04Å; F409-F418 HydrophobicContact CE2-CZ 4.03Å; F409-F418 AromaticContact CG-CE2 3.93Å; F409-F418 HydrophobicContact CG-CE2 3.93Å; F409-F418 HydrophobicContact CG-CZ 4.1Å; F409-F418 HydrophobicContact CZ-CE2 4.45Å; F409-F418 AromaticContact CZ-CZ 3.99Å; F409-F418 HydrophobicContact CZ-CZ 3.99Å; Y414-F418 HydrophobicContact CD1-CZ 4.43Å; Y414-F418 WeakPolarHBondContact O-CD2 3.18Å; Y414-F418 VanDerWaalsContact O-CG 3.23Å; Y414-F418 WeakPolarHBondContact O-CG 3.2Å; Y414-F418 PolarHBondContact O-N 2.87Å; P415-F418 PolarHBondContact O-N 2.53Å; V416-F418 PolarHBondContact O-N 2.71Å; F418-L421 PolarHBondContact O-N 3.25Å; F418-L422 VanDerWaalsContact O-CB 3.27Å; F418-L422 WeakPolarHBondContact O-CB 3.17Å; F418-L422 PolarHBondContact O-N 3.45Å
419	T	97	Very high	95.5	Very high	2 Å²	2	42.5 Å²	42.5	1%	0.012	22%	0.219	C	C	.	.	H	α-helix	trans	-66.2	-41.7	173.6	-61.9	0	0	0	0	111.9	T350 L354 F355 P415 V416 L421 L422 G423	T350-T419 WeakPolarHBondContact O-CG2 2.95Å; T350-T419 PolarHBondContact O-OG1 3.41Å; L354-T419 HydrophobicContact CB-CG2 4.3Å; L354-T419 HydrophobicContact CD2-CG2 4.36Å; L354-T419 HydrophobicContact CG-CG2 4.32Å; F355-T419 HydrophobicContact CB-CG2 3.61Å; P415-T419 WeakPolarHBondContact O-CB 3.48Å; P415-T419 PolarHBondContact O-N 2.89Å; P415-T419 PolarHBondContact O-OG1 3.08Å; V416-T419 PolarHBondContact O-N 3.48Å; T419-L421 VanDerWaalsContact C-N 3.34Å; T419-L421 PolarHBondContact O-N 2.96Å; T419-L422 PolarHBondContact O-N 2.96Å; T419-G423 PolarHBondContact O-N 3.23Å
420	C	97.7	Very high	95.9	Very high	35 Å²	35	40.4 Å²	40.4	24%	0.236	21%	0.21	C	C	.	.	H	α-helix	trans	-57.7	-47.1	172.7	-75.5	0	0	0	0	111.6	L354 V416 L417 G423 L424	L354-C420 VanDerWaalsContact CD1-SG 3.56Å; V416-C420 PolarHBondContact O-N 2.94Å; V416-C420 PolarHBondContact O-SG 3.44Å; V416-C420 VanDerWaalsContact O-SG 3.37Å; L417-C420 PolarHBondContact O-N 2.9Å; C420-G423 PolarHBondContact O-N 3.41Å; C420-L424 WeakPolarHBondContact O-CB 3.46Å; C420-L424 WeakPolarHBondContact O-CG 3.27Å; C420-L424 PolarHBondContact O-N 3.45Å
421	L	97.8	Very high	96.5	Very high	93 Å²	93	34.9 Å²	34.9	49%	0.487	18%	0.184	S	C	.	.	H	α-helix	trans	-65	-42.1	179.2	-178.4	57.2	0	0	0	111.6	L389 L417 F418 T419 S425	L389-L421 HydrophobicContact CD2-CD2 3.73Å; L389-L421 HydrophobicContact CD2-CG 4.09Å; L417-L421 WeakPolarHBondContact O-CB 3.49Å; L417-L421 PolarHBondContact O-N 2.98Å; F418-L421 PolarHBondContact O-N 3.25Å; T419-L421 VanDerWaalsContact C-N 3.34Å; T419-L421 PolarHBondContact O-N 2.96Å; L421-S425 WeakPolarHBondContact O-CB 3.06Å; L421-S425 PolarHBondContact O-N 2.9Å; L421-S425 PolarHBondContact O-OG 3.22Å
422	L	97.9	Very high	96.8	Very high	0 Å²	0	32.4 Å²	32.4	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-61.5	-49	176.2	-174.8	72.5	0	0	0	111	V318 I322 I323 F355 R386 L389 F393 F418 T419 S425 N426	V318-L422 HydrophobicContact CG1-CD1 4.5Å; I322-L422 HydrophobicContact CB-CD2 4.17Å; I322-L422 HydrophobicContact CD1-CD1 3.83Å; I322-L422 HydrophobicContact CD1-CD2 4.35Å; I322-L422 HydrophobicContact CG2-CD2 3.84Å; I323-L422 HydrophobicContact CD1-CD2 3.65Å; I323-L422 HydrophobicContact CG1-CD2 3.89Å; F355-L422 HydrophobicContact CD2-CD2 4.23Å; F355-L422 HydrophobicContact CD2-CG 4.37Å; F355-L422 HydrophobicContact CE2-CD2 4.15Å; F355-L422 HydrophobicContact CE2-CG 4.06Å; R386-L422 PolarHBondContact NH2-O 3.39Å; L389-L422 HydrophobicContact CD1-CB 4.19Å; L389-L422 HydrophobicContact CD1-CD1 3.53Å; L389-L422 HydrophobicContact CD1-CG 4.49Å; F393-L422 HydrophobicContact CE2-CB 4.26Å; F393-L422 HydrophobicContact CE2-CD2 4.18Å; F393-L422 HydrophobicContact CZ-CB 4.32Å; F393-L422 HydrophobicContact CZ-CD2 4.07Å; F418-L422 VanDerWaalsContact O-CB 3.27Å; F418-L422 WeakPolarHBondContact O-CB 3.17Å; F418-L422 PolarHBondContact O-N 3.45Å; T419-L422 PolarHBondContact O-N 2.96Å; L422-S425 PolarHBondContact O-OG 3.03Å; L422-N426 WeakPolarHBondContact O-CB 3.37Å; L422-N426 PolarHBondContact O-N 2.92Å
423	G	97.8	Very high	97	Very high	0 Å²	0	31 Å²	31	0%	0	16%	0.159	C	C	.	.	H	α-helix	trans	-61.8	-55.5	178.1	0	0	0	0	0	112.1	D359 T419 C420 S425 N426 G427	D359-G423 VanDerWaalsContact CA-O 3.27Å; D359-G423 WeakPolarHBondContact CA-O 3.11Å; T419-G423 PolarHBondContact O-N 3.23Å; C420-G423 PolarHBondContact O-N 3.41Å; G423-S425 PolarHBondContact O-N 3.2Å; G423-N426 WeakPolarHBondContact O-CB 3.22Å; G423-N426 PolarHBondContact O-N 2.95Å; G423-N426 VanDerWaalsContact O-N 3.13Å; G423-G427 PolarHBondContact O-N 3.27Å
424	L	98.1	Very high	97.1	Very high	78 Å²	78	26.9 Å²	26.9	41%	0.408	14%	0.138	S	C	.	.	H	α-helix	trans	-57.8	-47	-178.9	-75.6	167	0	0	0	112.2	A358 C361 C420 N426 G427 Y428	A358-L424 HydrophobicContact CB-CG 4.19Å; A358-L424 WeakPolarHBondContact O-CA 3.36Å; A358-L424 WeakPolarHBondContact O-CD2 3.44Å; C361-L424 HydrophobicContact CB-CD2 3.76Å; C420-L424 WeakPolarHBondContact O-CB 3.46Å; C420-L424 WeakPolarHBondContact O-CG 3.27Å; C420-L424 PolarHBondContact O-N 3.45Å; L424-N426 VanDerWaalsContact C-N 3.34Å; L424-G427 PolarHBondContact O-N 2.94Å; L424-Y428 VanDerWaalsContact O-CB 3.3Å; L424-Y428 WeakPolarHBondContact O-CB 3.35Å; L424-Y428 PolarHBondContact O-N 3.01Å
425	S	98	Very high	97.2	Very high	22 Å²	22	22.4 Å²	22.4	15%	0.154	12%	0.121	C	C	.	.	H	α-helix	trans	-67.2	-35.4	178.6	62.9	0	0	0	0	112.2	R386 L421 L422 G423 L429	R386-S425 PolarHBondContact NE-OG 3.3Å; L421-S425 WeakPolarHBondContact O-CB 3.06Å; L421-S425 PolarHBondContact O-N 2.9Å; L421-S425 PolarHBondContact O-OG 3.22Å; L422-S425 PolarHBondContact O-OG 3.03Å; G423-S425 PolarHBondContact O-N 3.2Å; S425-L429 VanDerWaalsContact O-CB 3.29Å; S425-L429 WeakPolarHBondContact O-CB 3.34Å; S425-L429 VanDerWaalsContact O-CG 3.32Å; S425-L429 WeakPolarHBondContact O-CG 3.2Å; S425-L429 PolarHBondContact O-N 2.91Å
426	N	97.8	Very high	97.3	Very high	4 Å²	4	22.2 Å²	22.2	2%	0.021	12%	0.119	C	C	.	.	H	α-helix	trans	-64.1	-53.1	173.5	-167.3	69	0	0	0	111.9	T319 F355 D359 R386 L422 G423 L424 Y428 S430	T319-N426 PolarHBondContact OG1-OD1 2.96Å; F355-N426 HydrophobicContact CE2-CB 4.43Å; D359-N426 PolarHBondContact OD1-ND2 2.89Å; R386-N426 PolarHBondContact NH1-OD1 3.35Å; L422-N426 WeakPolarHBondContact O-CB 3.37Å; L422-N426 PolarHBondContact O-N 2.92Å; G423-N426 WeakPolarHBondContact O-CB 3.22Å; G423-N426 PolarHBondContact O-N 2.95Å; G423-N426 VanDerWaalsContact O-N 3.13Å; L424-N426 VanDerWaalsContact C-N 3.34Å; N426-Y428 VanDerWaalsContact C-N 3.33Å; N426-Y428 PolarHBondContact O-N 3.3Å; N426-S430 WeakPolarHBondContact O-CB 3Å; N426-S430 PolarHBondContact O-N 3.27Å; N426-S430 PolarHBondContact O-OG 2.79Å
427	G	97.7	Very high	97.3	Very high	0 Å²	0	20 Å²	20	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-60.4	-46.4	-176.8	0	0	0	0	0	111.4	D359 G362 R363 G423 L424 T431	D359-G427 WeakPolarHBondContact O-CA 3.29Å; D359-G427 WeakPolarHBondContact OD1-CA 3.37Å; D359-G427 PolarHBondContact OD1-N 3.45Å; G362-G427 VanDerWaalsContact C-C 3.48Å; R363-G427 VanDerWaalsContact CG-CA 3.49Å; R363-G427 WeakPolarHBondContact CG-O 3.44Å; G423-G427 PolarHBondContact O-N 3.27Å; L424-G427 PolarHBondContact O-N 2.94Å; G427-T431 VanDerWaalsContact O-CB 3.25Å; G427-T431 WeakPolarHBondContact O-CB 3.34Å; G427-T431 PolarHBondContact O-N 3.08Å; G427-T431 PolarHBondContact O-OG1 2.89Å
428	Y	98.3	Very high	97.2	Very high	44 Å²	44	15.6 Å²	15.6	17%	0.173	8%	0.083	C	C	.	.	H	α-helix	trans	-65.1	-60.6	-179.7	-168.9	-104	0	0	0	111.7	G362 V365 T366 I369 V371 L424 N426 S430 T431 L432	G362-Y428 WeakPolarHBondContact O-CA 3.35Å; V365-Y428 HydrophobicContact CB-CD2 4.11Å; V365-Y428 HydrophobicContact CB-CE2 4.31Å; V365-Y428 HydrophobicContact CG1-CD2 3.99Å; V365-Y428 HydrophobicContact CG1-CE2 3.75Å; T366-Y428 HydrophobicContact CG2-CD2 3.43Å; T366-Y428 VanDerWaalsContact CG2-CD2 3.43Å; T366-Y428 HydrophobicContact CG2-CE2 3.64Å; T366-Y428 HydrophobicContact CG2-CG 4.15Å; I369-Y428 VanDerWaalsContact O-CE2 3.3Å; I369-Y428 WeakPolarHBondContact O-CE2 3.34Å; I369-Y428 PolarHBondContact O-OH 2.83Å; V371-Y428 PolarHBondContact N-OH 3.3Å; V371-Y428 WeakPolarHBondContact O-CE1 3.19Å; V371-Y428 PolarHBondContact O-OH 2.73Å; L424-Y428 VanDerWaalsContact O-CB 3.3Å; L424-Y428 WeakPolarHBondContact O-CB 3.35Å; L424-Y428 PolarHBondContact O-N 3.01Å; N426-Y428 VanDerWaalsContact C-N 3.33Å; N426-Y428 PolarHBondContact O-N 3.3Å; Y428-S430 PolarHBondContact O-N 3.22Å; Y428-T431 PolarHBondContact O-N 2.83Å; Y428-L432 HydrophobicContact CD1-CD1 4.02Å; Y428-L432 HydrophobicContact CE1-CD1 3.53Å; Y428-L432 HydrophobicContact CE1-CG 4.41Å; Y428-L432 WeakPolarHBondContact O-CG 3.48Å; Y428-L432 PolarHBondContact O-N 3.33Å; Y428-L432 VanDerWaalsContact O-N 3.13Å
429	L	98.1	Very high	97	Very high	9 Å²	9	18.2 Å²	18.2	5%	0.047	9%	0.094	C	C	.	.	H	α-helix	trans	-69.9	-37.6	-171.8	-60.6	175.5	0	0	0	112.6	L315 L379 L382 V383 S425 T431 L432 V433	L315-L429 HydrophobicContact CD1-CB 3.92Å; L315-L429 HydrophobicContact CD2-CB 3.66Å; L315-L429 HydrophobicContact CD2-CD1 4.01Å; L315-L429 HydrophobicContact CD2-CG 4.5Å; L315-L429 HydrophobicContact CG-CB 4.45Å; L379-L429 HydrophobicContact CD1-CD2 3.97Å; L382-L429 HydrophobicContact CB-CD1 4.07Å; L382-L429 HydrophobicContact CB-CD2 4.18Å; L382-L429 HydrophobicContact CD1-CD2 4.17Å; V383-L429 HydrophobicContact CG2-CD1 4.36Å; S425-L429 VanDerWaalsContact O-CB 3.29Å; S425-L429 WeakPolarHBondContact O-CB 3.34Å; S425-L429 VanDerWaalsContact O-CG 3.32Å; S425-L429 WeakPolarHBondContact O-CG 3.2Å; S425-L429 PolarHBondContact O-N 2.91Å; L429-T431 VanDerWaalsContact C-N 3.34Å; L429-L432 PolarHBondContact O-N 3.33Å; L429-V433 WeakPolarHBondContact O-CG2 3.18Å; L429-V433 PolarHBondContact O-N 3.07Å; L429-V433 VanDerWaalsContact O-N 3.07Å
430	S	97.2	Very high	96.8	Very high	1 Å²	1	19.9 Å²	19.9	1%	0.007	10%	0.102	C	C	.	.	H	α-helix	trans	-65.3	-40.5	177.7	68.1	0	0	0	0	111.3	R363 N426 Y428 V433 L434	R363-S430 PolarHBondContact NH1-OG 3.27Å; R363-S430 PolarHBondContact NH2-OG 3.25Å; N426-S430 WeakPolarHBondContact O-CB 3Å; N426-S430 PolarHBondContact O-N 3.27Å; N426-S430 PolarHBondContact O-OG 2.79Å; Y428-S430 PolarHBondContact O-N 3.22Å; S430-V433 PolarHBondContact O-N 3.26Å; S430-L434 WeakPolarHBondContact O-CB 3.41Å; S430-L434 VanDerWaalsContact O-CG 3.28Å; S430-L434 WeakPolarHBondContact O-CG 3.35Å; S430-L434 PolarHBondContact O-N 3.45Å
431	T	97.6	Very high	96.5	Very high	0 Å²	0	19.1 Å²	19.1	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-63.7	-45.9	177.9	-56.2	0	0	0	0	110.7	Q199 I202 R363 T366 G427 Y428 L429 V433 L434 I435	Q199-T431 HydrophobicContact CB-CG2 4.39Å; Q199-T431 HydrophobicContact CG-CG2 3.99Å; I202-T431 HydrophobicContact CB-CG2 4.21Å; I202-T431 HydrophobicContact CD1-CG2 4.01Å; I202-T431 HydrophobicContact CG2-CG2 3.82Å; I202-T431 VanDerWaalsContact CG2-OG1 3.28Å; I202-T431 WeakPolarHBondContact CG2-OG1 3.49Å; R363-T431 VanDerWaalsContact CG-OG1 3.26Å; R363-T431 WeakPolarHBondContact CG-OG1 3.37Å; R363-T431 PolarHBondContact NH1-OG1 3.25Å; T366-T431 HydrophobicContact CG2-CG2 4.18Å; T366-T431 WeakPolarHBondContact OG1-CG2 3.31Å; G427-T431 VanDerWaalsContact O-CB 3.25Å; G427-T431 WeakPolarHBondContact O-CB 3.34Å; G427-T431 PolarHBondContact O-N 3.08Å; G427-T431 PolarHBondContact O-OG1 2.89Å; Y428-T431 PolarHBondContact O-N 2.83Å; L429-T431 VanDerWaalsContact C-N 3.34Å; T431-V433 PolarHBondContact O-N 3.37Å; T431-L434 PolarHBondContact O-N 3.3Å; T431-I435 HydrophobicContact CG2-CG2 4.14Å; T431-I435 VanDerWaalsContact O-CG1 3.28Å; T431-I435 WeakPolarHBondContact O-CG1 3.5Å; T431-I435 WeakPolarHBondContact O-CG2 3.29Å; T431-I435 PolarHBondContact O-N 3.45Å
432	L	97.3	Very high	96.1	Very high	0 Å²	0	16.4 Å²	16.4	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-55.6	-49.3	176	-67.4	-175	0	0	0	112.4	T366 Q370 V371 Y428 L429 L434 I435 Y436	T366-L432 HydrophobicContact CG2-CD2 3.83Å; T366-L432 HydrophobicContact CG2-CG 4.08Å; Q370-L432 HydrophobicContact CB-CD2 4.12Å; Q370-L432 HydrophobicContact CG-CD2 4.3Å; V371-L432 WeakPolarHBondContact O-CD1 3.48Å; Y428-L432 HydrophobicContact CD1-CD1 4.02Å; Y428-L432 HydrophobicContact CE1-CD1 3.53Å; Y428-L432 HydrophobicContact CE1-CG 4.41Å; Y428-L432 WeakPolarHBondContact O-CG 3.48Å; Y428-L432 PolarHBondContact O-N 3.33Å; Y428-L432 VanDerWaalsContact O-N 3.13Å; L429-L432 PolarHBondContact O-N 3.33Å; L432-L434 VanDerWaalsContact C-N 3.34Å; L432-L434 PolarHBondContact O-N 3.37Å; L432-I435 HydrophobicContact CD2-CD1 4.12Å; L432-I435 VanDerWaalsContact O-CG1 3.32Å; L432-I435 WeakPolarHBondContact O-CG1 3.38Å; L432-I435 PolarHBondContact O-N 3.12Å; L432-Y436 HydrophobicContact CB-CD2 4.18Å; L432-Y436 HydrophobicContact CB-CE2 3.76Å; L432-Y436 HydrophobicContact CD1-CE2 4.47Å; L432-Y436 HydrophobicContact CD2-CE2 4.39Å; L432-Y436 HydrophobicContact CG-CE2 4.42Å; L432-Y436 WeakPolarHBondContact O-CB 3.41Å; L432-Y436 WeakPolarHBondContact O-CD2 3.33Å; L432-Y436 PolarHBondContact O-N 3.06Å
433	V	97	Very high	95.6	Very high	1 Å²	1	20.8 Å²	20.8	1%	0.006	10%	0.101	C	C	.	.	H	α-helix	trans	-60.3	-45.4	-179.5	170.4	0	0	0	0	111.2	L308 C311 A312 L315 L379 L429 S430 T431 G437 M453	L308-V433 HydrophobicContact CB-CG1 4.22Å; L308-V433 WeakPolarHBondContact O-CG1 3.36Å; C311-V433 HydrophobicContact CB-CG1 4.33Å; C311-V433 HydrophobicContact CB-CG2 3.65Å; A312-V433 HydrophobicContact CB-CG1 3.77Å; L315-V433 HydrophobicContact CD1-CG2 3.93Å; L379-V433 HydrophobicContact CD1-CG2 4.29Å; L379-V433 HydrophobicContact CD2-CG2 4.01Å; L379-V433 HydrophobicContact CG-CG2 4.41Å; L429-V433 WeakPolarHBondContact O-CG2 3.18Å; L429-V433 PolarHBondContact O-N 3.07Å; L429-V433 VanDerWaalsContact O-N 3.07Å; S430-V433 PolarHBondContact O-N 3.26Å; T431-V433 PolarHBondContact O-N 3.37Å; V433-G437 PolarHBondContact O-N 2.99Å; V433-G437 VanDerWaalsContact O-N 3.14Å; V433-M453 HydrophobicContact CG1-CE 3.44Å; V433-M453 VanDerWaalsContact CG1-CE 3.44Å
434	L	96.7	Very high	95.1	Very high	8 Å²	8	24 Å²	24	4%	0.042	12%	0.116	C	C	.	.	H	α-helix	trans	-68	-40.1	-179.5	-68.1	176.2	0	0	0	112.7	Y187 I202 S430 T431 L432 P438 M453	Y187-L434 HydrophobicContact CE1-CD1 4.18Å; I202-L434 HydrophobicContact CD1-CB 3.76Å; I202-L434 HydrophobicContact CD1-CD1 4.38Å; I202-L434 HydrophobicContact CG1-CD1 4.38Å; S430-L434 WeakPolarHBondContact O-CB 3.41Å; S430-L434 VanDerWaalsContact O-CG 3.28Å; S430-L434 WeakPolarHBondContact O-CG 3.35Å; S430-L434 PolarHBondContact O-N 3.45Å; T431-L434 PolarHBondContact O-N 3.3Å; L432-L434 VanDerWaalsContact C-N 3.34Å; L432-L434 PolarHBondContact O-N 3.37Å; L434-P438 WeakPolarHBondContact O-CD 3.41Å; L434-M453 HydrophobicContact CD2-CB 3.89Å
435	I	95.8	Very high	94.8	Very high	0 Å²	0	21.3 Å²	21.3	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-75.2	-29.7	178.1	67.4	-176.1	0	0	0	112.8	M195 A198 Q199 I202 Q370 T431 L432 K439	M195-I435 HydrophobicContact CB-CB 4.48Å; M195-I435 HydrophobicContact CE-CB 4.08Å; M195-I435 HydrophobicContact CE-CD1 3.58Å; M195-I435 HydrophobicContact CE-CG1 3.53Å; A198-I435 HydrophobicContact CB-CG2 3.83Å; Q199-I435 HydrophobicContact CB-CG2 4.32Å; I202-I435 HydrophobicContact CD1-CG2 3.46Å; I202-I435 VanDerWaalsContact CD1-CG2 3.46Å; Q370-I435 HydrophobicContact CG-CD1 4.3Å; T431-I435 HydrophobicContact CG2-CG2 4.14Å; T431-I435 VanDerWaalsContact O-CG1 3.28Å; T431-I435 WeakPolarHBondContact O-CG1 3.5Å; T431-I435 WeakPolarHBondContact O-CG2 3.29Å; T431-I435 PolarHBondContact O-N 3.45Å; L432-I435 HydrophobicContact CD2-CD1 4.12Å; L432-I435 VanDerWaalsContact O-CG1 3.32Å; L432-I435 WeakPolarHBondContact O-CG1 3.38Å; L432-I435 PolarHBondContact O-N 3.12Å; I435-K439 VanDerWaalsContact O-CG 3.25Å; I435-K439 WeakPolarHBondContact O-CG 3.14Å
436	Y	96.3	Very high	94.6	Very high	3 Å²	3	20.3 Å²	20.3	1%	0.012	10%	0.095	C	C	.	.	H	α-helix	trans	-73.9	-35.7	177.7	-71.2	-26.6	0	0	0	112.6	M195 Q370 G373 P374 L379 L432 K439 I440	M195-Y436 HydrophobicContact CE-CD1 3.44Å; M195-Y436 VanDerWaalsContact CE-CD1 3.44Å; M195-Y436 HydrophobicContact CE-CE1 3.54Å; Q370-Y436 VanDerWaalsContact C-OH 3.29Å; Q370-Y436 PolarHBondContact O-OH 3.11Å; G373-Y436 VanDerWaalsContact C-CE2 3.42Å; G373-Y436 WeakPolarHBondContact CA-OH 3.42Å; G373-Y436 PolarHBondContact N-OH 3.35Å; P374-Y436 HydrophobicContact CB-CD1 4Å; P374-Y436 HydrophobicContact CB-CD2 4.07Å; P374-Y436 HydrophobicContact CB-CG 3.72Å; P374-Y436 HydrophobicContact CG-CD1 4.31Å; L379-Y436 HydrophobicContact CD2-CD2 4.15Å; L379-Y436 HydrophobicContact CD2-CE2 4.26Å; L432-Y436 HydrophobicContact CB-CD2 4.18Å; L432-Y436 HydrophobicContact CB-CE2 3.76Å; L432-Y436 HydrophobicContact CD1-CE2 4.47Å; L432-Y436 HydrophobicContact CD2-CE2 4.39Å; L432-Y436 HydrophobicContact CG-CE2 4.42Å; L432-Y436 WeakPolarHBondContact O-CB 3.41Å; L432-Y436 WeakPolarHBondContact O-CD2 3.33Å; L432-Y436 PolarHBondContact O-N 3.06Å; Y436-K439 WeakPolarHBondContact O-CA 3.49Å; Y436-K439 PolarHBondContact O-N 3.38Å; Y436-I440 PolarHBondContact O-N 3.14Å
437	G	95.7	Very high	94.4	Very high	0 Å²	0	22 Å²	22	0%	0	10%	0.103	C	C	.	.	G	3₁₀ helix	trans	-47.4	-59.7	-177	0	0	0	0	0	114.7	V433 K439 I440 T449	V433-G437 PolarHBondContact O-N 2.99Å; V433-G437 VanDerWaalsContact O-N 3.14Å; G437-K439 PolarHBondContact O-N 3.42Å; G437-I440 WeakPolarHBondContact O-CG1 3.34Å; G437-I440 PolarHBondContact O-N 3.43Å; G437-T449 WeakPolarHBondContact O-CG2 3.22Å
438	P	94.5	Very high	94.2	Very high	4 Å²	4	22.1 Å²	22.1	3%	0.026	10%	0.104	C	C	.	.	G	3₁₀ helix	trans	-69.9	-9.5	179.1	26.7	-33.8	0	0	0	114.6	L434 V441 A446 S450	L434-P438 WeakPolarHBondContact O-CD 3.41Å; P438-V441 WeakPolarHBondContact O-CG2 3.42Å; P438-A446 HydrophobicContact CB-CB 4.01Å; P438-A446 WeakPolarHBondContact CB-O 3.36Å; P438-S450 VanDerWaalsContact CB-OG 3.3Å; P438-S450 WeakPolarHBondContact CB-OG 3.44Å; P438-S450 WeakPolarHBondContact CG-OG 3.03Å
439	K	93.4	Very high	94.1	Very high	79 Å²	79	20 Å²	20	34%	0.343	10%	0.096	S	C	.	.	G	3₁₀ helix	trans	-94.8	-11.2	-177.6	-58	-58.2	174.7	-160.5	0	114.2	G191 F193 M195 I435 Y436 G437 V441	G191-K439 PolarHBondContact O-NZ 2.87Å; F193-K439 WeakPolarHBondContact O-CE 3.47Å; F193-K439 PolarHBondContact O-NZ 3.39Å; M195-K439 HydrophobicContact CG-CD 4.13Å; M195-K439 HydrophobicContact CG-CG 3.72Å; M195-K439 HydrophobicContact SD-CG 4.03Å; I435-K439 VanDerWaalsContact O-CG 3.25Å; I435-K439 WeakPolarHBondContact O-CG 3.14Å; Y436-K439 WeakPolarHBondContact O-CA 3.49Å; Y436-K439 PolarHBondContact O-N 3.38Å; G437-K439 PolarHBondContact O-N 3.42Å; K439-V441 VanDerWaalsContact C-N 3.35Å
440	I	92.8	Very high	94	Very high	36 Å²	36	19.9 Å²	19.9	19%	0.185	10%	0.095	C	C	.	.	S	Bend	trans	-93.6	2.3	174.5	62.2	162.5	0	0	0	113.1	K304 T305 L308 P374 Y436 G437	K304-I440 VanDerWaalsContact CE-O 3.27Å; K304-I440 WeakPolarHBondContact CE-O 3.29Å; K304-I440 HydrophobicContact CG-CD1 4.2Å; K304-I440 HydrophobicContact CG-CG1 4.44Å; K304-I440 VanDerWaalsContact O-CD1 3.23Å; K304-I440 WeakPolarHBondContact O-CD1 3.29Å; T305-I440 HydrophobicContact CG2-CD1 4.22Å; L308-I440 HydrophobicContact CD1-CD1 3.7Å; L308-I440 HydrophobicContact CD1-CG1 4.26Å; L308-I440 HydrophobicContact CG-CD1 4.49Å; P374-I440 HydrophobicContact CB-CG2 3.71Å; P374-I440 HydrophobicContact CG-CG2 4.42Å; Y436-I440 PolarHBondContact O-N 3.14Å; G437-I440 WeakPolarHBondContact O-CG1 3.34Å; G437-I440 PolarHBondContact O-N 3.43Å
441	V	91.8	Very high	93.9	Very high	19 Å²	19	19.9 Å²	19.9	12%	0.115	10%	0.095	C	C	.	.	S	Bend	trans	-119	160.3	176.7	-63.6	0	0	0	0	110.4	K304 P438 K439 L445 T449	K304-V441 HydrophobicContact CB-CG1 4.35Å; K304-V441 HydrophobicContact CG-CG1 4.17Å; P438-V441 WeakPolarHBondContact O-CG2 3.42Å; K439-V441 VanDerWaalsContact C-N 3.35Å; V441-L445 HydrophobicContact CB-CB 4.34Å; V441-L445 HydrophobicContact CG2-CB 4.31Å; V441-T449 HydrophobicContact CG1-CG2 4.09Å; V441-T449 HydrophobicContact CG2-CG2 3.97Å; V441-T449 WeakPolarHBondContact CG2-OG1 3.39Å
442	P	89.5	Confident	93.8	Very high	37 Å²	37	20.1 Å²	20.1	24%	0.24	10%	0.097	C	C	.	.			trans	-57.8	149.3	170.6	-22.8	33.9	0	0	0	112	V269 E444 L445 A446	V269-P442 HydrophobicContact CB-CG 4.34Å; V269-P442 HydrophobicContact CG1-CG 3.77Å; V269-P442 HydrophobicContact CG2-CG 4.45Å; P442-E444 PolarHBondContact O-N 3.05Å; P442-E444 VanDerWaalsContact O-N 3.12Å; P442-L445 PolarHBondContact O-N 2.98Å; P442-A446 PolarHBondContact O-N 3.29Å
443	R	87.3	Confident	93.8	Very high	92 Å²	92	20.2 Å²	20.2	35%	0.347	10%	0.097	S	C	.	.	H	α-helix	trans	-54.6	-34.7	-176.5	-175.7	173.9	167.6	-170.3	-5.2	113.5	Y259 Y260 V264 L445 A446	Y259-R443 PolarHBondContact O-NH2 3.39Å; Y260-R443 PolarHBondContact O-NH2 2.89Å; V264-R443 HydrophobicContact CG2-CG 4.1Å; R443-L445 PolarHBondContact O-N 3.12Å; R443-A446 VanDerWaalsContact O-CB 3.3Å; R443-A446 WeakPolarHBondContact O-CB 3.25Å; R443-A446 PolarHBondContact O-N 3.48Å; R443-A446 VanDerWaalsContact O-N 3.16Å
444	E	87.2	Confident	93.7	Very high	68 Å²	68	20.6 Å²	20.6	32%	0.318	10%	0.099	S	C	.	.	H	α-helix	trans	-61	-28.1	176.6	-64.1	171.2	-145.5	0	0	113.4	V264 A265 P266 V267 P442	V264-E444 HydrophobicContact CB-CG 4.04Å; V264-E444 HydrophobicContact CG1-CG 3.92Å; A265-E444 VanDerWaalsContact O-OE1 3.12Å; P266-E444 WeakPolarHBondContact CA-OE2 3.48Å; V267-E444 PolarHBondContact N-OE1 3.33Å; V267-E444 PolarHBondContact N-OE2 3.34Å; P442-E444 PolarHBondContact O-N 3.05Å; P442-E444 VanDerWaalsContact O-N 3.12Å
445	L	91.7	Very high	93.7	Very high	21 Å²	21	23.9 Å²	23.9	11%	0.11	11%	0.113	C	C	.	.	H	α-helix	trans	-100.3	-3.1	179	-60.3	-172.9	0	0	0	112.9	F270 P297 I301 V441 P442 R443 E447 A448 T449	F270-L445 HydrophobicContact CD2-CD1 4.45Å; F270-L445 HydrophobicContact CE2-CD1 3.47Å; F270-L445 VanDerWaalsContact CE2-CD1 3.47Å; F270-L445 HydrophobicContact CZ-CD1 3.99Å; P297-L445 HydrophobicContact CG-CD1 4.11Å; P297-L445 HydrophobicContact CG-CD2 3.84Å; I301-L445 HydrophobicContact CG1-CD1 4.21Å; V441-L445 HydrophobicContact CB-CB 4.34Å; V441-L445 HydrophobicContact CG2-CB 4.31Å; P442-L445 PolarHBondContact O-N 2.98Å; R443-L445 PolarHBondContact O-N 3.12Å; L445-E447 VanDerWaalsContact C-N 3.33Å; L445-E447 PolarHBondContact O-N 2.96Å; L445-A448 PolarHBondContact O-N 3.38Å; L445-T449 VanDerWaalsContact O-CB 3.23Å; L445-T449 WeakPolarHBondContact O-CB 3.44Å; L445-T449 PolarHBondContact O-N 2.95Å; L445-T449 PolarHBondContact O-OG1 3.32Å
446	A	92.8	Very high	93.7	Very high	1 Å²	1	25.6 Å²	25.6	1%	0.008	12%	0.12	C	C	.	.	H	α-helix	trans	-64.1	-37.4	-172.4	0	0	0	0	0	112.6	G191 P438 P442 R443 T449 S450	G191-A446 WeakPolarHBondContact O-CB 3.37Å; P438-A446 HydrophobicContact CB-CB 4.01Å; P438-A446 WeakPolarHBondContact CB-O 3.36Å; P442-A446 PolarHBondContact O-N 3.29Å; R443-A446 VanDerWaalsContact O-CB 3.3Å; R443-A446 WeakPolarHBondContact O-CB 3.25Å; R443-A446 PolarHBondContact O-N 3.48Å; R443-A446 VanDerWaalsContact O-N 3.16Å; A446-T449 PolarHBondContact O-N 3.09Å; A446-S450 PolarHBondContact O-N 2.93Å; A446-S450 PolarHBondContact O-OG 3.43Å
447	E	93.5	Very high	93.7	Very high	40 Å²	40	27.4 Å²	27.4	19%	0.187	13%	0.129	C	C	.	.	H	α-helix	trans	-63.2	-55.2	176.7	-179.1	173.6	160.9	0	0	111.4	V126 R134 G188 L445 T449 S450 V451	V126-E447 HydrophobicContact CG1-CB 4.28Å; V126-E447 HydrophobicContact CG1-CG 3.78Å; R134-E447 IonicContact CZ-OE1 3.48Å; R134-E447 IonicContact NH1-OE1 3.37Å; R134-E447 PolarHBondContact NH1-OE1 3.39Å; R134-E447 IonicContact NH2-OE1 2.66Å; R134-E447 PolarHBondContact NH2-OE1 3.41Å; G188-E447 VanDerWaalsContact O-CA 3.29Å; G188-E447 WeakPolarHBondContact O-CA 3.29Å; L445-E447 VanDerWaalsContact C-N 3.33Å; L445-E447 PolarHBondContact O-N 2.96Å; E447-T449 VanDerWaalsContact C-N 3.26Å; E447-T449 PolarHBondContact O-N 2.87Å; E447-S450 PolarHBondContact O-N 3.44Å; E447-V451 PolarHBondContact O-N 3.01Å
448	A	94.1	Very high	93.6	Very high	2 Å²	2	28.6 Å²	28.6	2%	0.017	14%	0.137	C	C	.	.	H	α-helix	trans	-59.6	-38.4	177.8	0	0	0	0	0	112.2	F123 V126 P296 I301 L445 V451 V452	F123-A448 HydrophobicContact CD2-CB 4.44Å; F123-A448 HydrophobicContact CE2-CB 3.97Å; V126-A448 HydrophobicContact CG1-CB 4.3Å; P296-A448 HydrophobicContact CB-CB 3.42Å; P296-A448 VanDerWaalsContact CB-CB 3.42Å; P296-A448 HydrophobicContact CG-CB 3.51Å; I301-A448 HydrophobicContact CD1-CB 4.02Å; L445-A448 PolarHBondContact O-N 3.38Å; A448-V451 WeakPolarHBondContact O-CB 3.37Å; A448-V451 PolarHBondContact O-N 3.04Å; A448-V452 WeakPolarHBondContact O-CG2 3.49Å; A448-V452 PolarHBondContact O-N 2.86Å
449	T	95.9	Very high	93.7	Very high	0 Å²	0	30 Å²	30	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-66.5	-38.5	178.8	-59.7	0	0	0	0	111.8	I301 T305 G437 V441 L445 A446 E447 V451 V452 M453	I301-T449 HydrophobicContact CG2-CG2 4.15Å; T305-T449 HydrophobicContact CG2-CG2 3.53Å; G437-T449 WeakPolarHBondContact O-CG2 3.22Å; V441-T449 HydrophobicContact CG1-CG2 4.09Å; V441-T449 HydrophobicContact CG2-CG2 3.97Å; V441-T449 WeakPolarHBondContact CG2-OG1 3.39Å; L445-T449 VanDerWaalsContact O-CB 3.23Å; L445-T449 WeakPolarHBondContact O-CB 3.44Å; L445-T449 PolarHBondContact O-N 2.95Å; L445-T449 PolarHBondContact O-OG1 3.32Å; A446-T449 PolarHBondContact O-N 3.09Å; E447-T449 VanDerWaalsContact C-N 3.26Å; E447-T449 PolarHBondContact O-N 2.87Å; T449-V451 VanDerWaalsContact C-N 3.29Å; T449-V451 PolarHBondContact O-N 3.29Å; T449-V452 WeakPolarHBondContact O-CB 3.25Å; T449-V452 PolarHBondContact O-N 3.45Å; T449-V452 VanDerWaalsContact O-N 3.17Å; T449-M453 WeakPolarHBondContact O-CG 3.42Å; T449-M453 PolarHBondContact O-N 3.5Å
450	S	95.4	Very high	93.8	Very high	5 Å²	5	26.2 Å²	26.2	4%	0.035	13%	0.129	C	C	.	.	H	α-helix	trans	-63.1	-37.5	174.4	-53.1	0	0	0	0	111.6	Y187 G191 P438 A446 E447 M453 L454	Y187-S450 WeakPolarHBondContact O-CB 3.27Å; G191-S450 WeakPolarHBondContact CA-OG 3.37Å; P438-S450 VanDerWaalsContact CB-OG 3.3Å; P438-S450 WeakPolarHBondContact CB-OG 3.44Å; P438-S450 WeakPolarHBondContact CG-OG 3.03Å; A446-S450 PolarHBondContact O-N 2.93Å; A446-S450 PolarHBondContact O-OG 3.43Å; E447-S450 PolarHBondContact O-N 3.44Å; S450-M453 PolarHBondContact O-N 3.47Å; S450-L454 PolarHBondContact O-N 2.75Å; S450-L454 VanDerWaalsContact O-N 3.13Å
451	V	95.1	Very high	93.9	Very high	2 Å²	2	27.6 Å²	27.6	1%	0.012	14%	0.137	C	C	.	.	H	α-helix	trans	-64.3	-41	173.5	-178.6	0	0	0	0	111.2	L119 F123 V126 E447 A448 T449 M453 L454 F455	L119-V451 HydrophobicContact CD1-CG1 3.93Å; F123-V451 HydrophobicContact CB-CG1 3.85Å; F123-V451 HydrophobicContact CD2-CB 4.46Å; F123-V451 HydrophobicContact CD2-CG1 4.4Å; V126-V451 HydrophobicContact CG2-CG2 4.08Å; E447-V451 PolarHBondContact O-N 3.01Å; A448-V451 WeakPolarHBondContact O-CB 3.37Å; A448-V451 PolarHBondContact O-N 3.04Å; T449-V451 VanDerWaalsContact C-N 3.29Å; T449-V451 PolarHBondContact O-N 3.29Å; V451-M453 VanDerWaalsContact C-N 3.33Å; V451-M453 PolarHBondContact O-N 3.35Å; V451-L454 PolarHBondContact O-N 3.25Å; V451-F455 PolarHBondContact O-N 2.96Å
452	V	96.3	Very high	93.9	Very high	5 Å²	5	30.6 Å²	30.6	3%	0.03	15%	0.15	C	C	.	.	H	α-helix	trans	-63.4	-38	174.4	171.4	0	0	0	0	111.8	F123 L298 I301 L302 A448 T449 L454 F455 Y456	F123-V452 HydrophobicContact CD2-CG2 3.83Å; F123-V452 HydrophobicContact CE2-CG2 3.55Å; F123-V452 HydrophobicContact CZ-CG2 4.46Å; L298-V452 HydrophobicContact CD1-CG2 4.07Å; I301-V452 HydrophobicContact CG2-CB 4.17Å; I301-V452 HydrophobicContact CG2-CG1 4.25Å; I301-V452 HydrophobicContact CG2-CG2 3.96Å; L302-V452 HydrophobicContact CD2-CG1 3.8Å; A448-V452 WeakPolarHBondContact O-CG2 3.49Å; A448-V452 PolarHBondContact O-N 2.86Å; T449-V452 WeakPolarHBondContact O-CB 3.25Å; T449-V452 PolarHBondContact O-N 3.45Å; T449-V452 VanDerWaalsContact O-N 3.17Å; V452-L454 VanDerWaalsContact C-N 3.31Å; V452-L454 PolarHBondContact O-N 3.06Å; V452-F455 WeakPolarHBondContact O-CA 3.23Å; V452-F455 WeakPolarHBondContact O-CB 3.26Å; V452-F455 PolarHBondContact O-N 3.25Å; V452-F455 VanDerWaalsContact O-N 3.08Å; V452-Y456 HydrophobicContact CG1-CD2 4.09Å; V452-Y456 HydrophobicContact CG1-CE2 3.61Å; V452-Y456 WeakPolarHBondContact O-CD2 3.45Å; V452-Y456 PolarHBondContact O-N 3.05Å
453	M	97.1	Very high	94.1	Very high	2 Å²	2	32.3 Å²	32.3	1%	0.01	16%	0.157	C	C	.	.	H	α-helix	trans	-62.3	-38.9	174.8	-68.3	-51.6	-59.9	0	0	112.4	T305 L308 A312 V433 L434 T449 S450 V451 F455 Y456 M457	T305-M453 HydrophobicContact CG2-SD 4.22Å; L308-M453 HydrophobicContact CB-CE 3.92Å; L308-M453 HydrophobicContact CB-SD 4.38Å; A312-M453 HydrophobicContact CB-CE 4.32Å; V433-M453 HydrophobicContact CG1-CE 3.44Å; V433-M453 VanDerWaalsContact CG1-CE 3.44Å; L434-M453 HydrophobicContact CD2-CB 3.89Å; T449-M453 WeakPolarHBondContact O-CG 3.42Å; T449-M453 PolarHBondContact O-N 3.5Å; S450-M453 PolarHBondContact O-N 3.47Å; V451-M453 VanDerWaalsContact C-N 3.33Å; V451-M453 PolarHBondContact O-N 3.35Å; M453-F455 VanDerWaalsContact C-N 3.32Å; M453-Y456 PolarHBondContact O-N 2.88Å; M453-Y456 HydrophobicContact SD-CD2 4.09Å; M453-Y456 HydrophobicContact SD-CE2 4.47Å; M453-M457 PolarHBondContact O-N 2.97Å
454	L	95.8	Very high	94.5	Very high	8 Å²	8	28 Å²	28	4%	0.042	14%	0.141	C	C	.	.	H	α-helix	trans	-67.6	-32.9	172.1	-70.2	177.3	0	0	0	112.5	L119 S184 Y187 S450 V451 V452 M457 S458	L119-L454 HydrophobicContact CD1-CB 4.25Å; L119-L454 HydrophobicContact CD2-CB 4.48Å; S184-L454 VanDerWaalsContact CA-CD1 3.49Å; Y187-L454 HydrophobicContact CD1-CD1 4.42Å; Y187-L454 HydrophobicContact CD1-CD2 4.12Å; Y187-L454 HydrophobicContact CD1-CG 4.36Å; Y187-L454 HydrophobicContact CD2-CD1 3.94Å; Y187-L454 HydrophobicContact CD2-CD2 4.15Å; Y187-L454 HydrophobicContact CE1-CD2 4.13Å; Y187-L454 HydrophobicContact CE2-CD2 4.18Å; Y187-L454 HydrophobicContact CG-CD1 3.75Å; Y187-L454 HydrophobicContact CG-CD2 4.1Å; Y187-L454 HydrophobicContact CG-CG 4.18Å; S450-L454 PolarHBondContact O-N 2.75Å; S450-L454 VanDerWaalsContact O-N 3.13Å; V451-L454 PolarHBondContact O-N 3.25Å; V452-L454 VanDerWaalsContact C-N 3.31Å; V452-L454 PolarHBondContact O-N 3.06Å; L454-M457 HydrophobicContact CD2-CE 4.15Å; L454-M457 HydrophobicContact CD2-SD 4.11Å; L454-M457 WeakPolarHBondContact O-CB 3.23Å; L454-M457 PolarHBondContact O-N 3.4Å; L454-S458 PolarHBondContact O-N 3.45Å; L454-S458 PolarHBondContact O-OG 3.21Å; L454-S458 VanDerWaalsContact O-OG 3.08Å
455	F	95.4	Very high	94.7	Very high	77 Å²	77	27.6 Å²	27.6	34%	0.338	15%	0.146	S	C	.	.	H	α-helix	trans	-62.5	-44.7	173.4	-179.7	-95.7	0	0	0	111.4	L119 V120 V451 V452 M453 M457 S458 V459	L119-F455 HydrophobicContact CD2-CB 4.09Å; L119-F455 HydrophobicContact CD2-CD2 4.3Å; V120-F455 HydrophobicContact CG2-CD2 4.23Å; V120-F455 HydrophobicContact CG2-CE2 3.94Å; V451-F455 PolarHBondContact O-N 2.96Å; V452-F455 WeakPolarHBondContact O-CA 3.23Å; V452-F455 WeakPolarHBondContact O-CB 3.26Å; V452-F455 PolarHBondContact O-N 3.25Å; V452-F455 VanDerWaalsContact O-N 3.08Å; M453-F455 VanDerWaalsContact C-N 3.32Å; F455-M457 VanDerWaalsContact C-N 3.32Å; F455-M457 PolarHBondContact O-N 3.18Å; F455-S458 PolarHBondContact O-N 2.81Å; F455-V459 HydrophobicContact CD1-CG2 4.21Å; F455-V459 HydrophobicContact CE1-CG2 3.77Å; F455-V459 HydrophobicContact CE2-CG2 4.44Å; F455-V459 HydrophobicContact CZ-CG2 3.9Å; F455-V459 WeakPolarHBondContact O-CG2 3.33Å; F455-V459 PolarHBondContact O-N 3.01Å
456	Y	96.6	Very high	94.6	Very high	37 Å²	37	29 Å²	29	15%	0.145	16%	0.16	C	C	.	.	H	α-helix	trans	-59.8	-41.2	173.1	-69	-49.8	0	0	0	112.8	L302 G309 V313 V452 M453 V459 G460	L302-Y456 HydrophobicContact CD2-CE1 4.45Å; L302-Y456 WeakPolarHBondContact CD2-OH 3.46Å; G309-Y456 VanDerWaalsContact CA-CE2 3.49Å; V313-Y456 HydrophobicContact CG2-CD1 4.12Å; V313-Y456 WeakPolarHBondContact CG2-O 3.44Å; V452-Y456 HydrophobicContact CG1-CD2 4.09Å; V452-Y456 HydrophobicContact CG1-CE2 3.61Å; V452-Y456 WeakPolarHBondContact O-CD2 3.45Å; V452-Y456 PolarHBondContact O-N 3.05Å; M453-Y456 PolarHBondContact O-N 2.88Å; M453-Y456 HydrophobicContact SD-CD2 4.09Å; M453-Y456 HydrophobicContact SD-CE2 4.47Å; Y456-V459 PolarHBondContact O-N 3.39Å; Y456-G460 PolarHBondContact O-N 3.08Å
457	M	95.8	Very high	94.6	Very high	40 Å²	40	31.1 Å²	31.1	20%	0.197	18%	0.175	C	C	.	.	H	α-helix	trans	-56.8	-50.6	172.9	170.8	-175.9	103.6	0	0	111.3	Y316 M453 L454 F455 V459 G460 L461	Y316-M457 HydrophobicContact CD1-CG 3.82Å; Y316-M457 HydrophobicContact CD2-CB 3.83Å; Y316-M457 HydrophobicContact CD2-CG 3.58Å; Y316-M457 HydrophobicContact CE1-CG 3.69Å; Y316-M457 HydrophobicContact CE1-SD 3.86Å; Y316-M457 HydrophobicContact CE2-CB 3.81Å; Y316-M457 HydrophobicContact CE2-CG 3.47Å; Y316-M457 VanDerWaalsContact CE2-CG 3.47Å; Y316-M457 HydrophobicContact CE2-SD 4.03Å; Y316-M457 HydrophobicContact CG-CB 4.4Å; Y316-M457 HydrophobicContact CG-CG 3.76Å; Y316-M457 VanDerWaalsContact CZ-SD 3.56Å; M453-M457 PolarHBondContact O-N 2.97Å; L454-M457 HydrophobicContact CD2-CE 4.15Å; L454-M457 HydrophobicContact CD2-SD 4.11Å; L454-M457 WeakPolarHBondContact O-CB 3.23Å; L454-M457 PolarHBondContact O-N 3.4Å; F455-M457 VanDerWaalsContact C-N 3.32Å; F455-M457 PolarHBondContact O-N 3.18Å; M457-V459 VanDerWaalsContact C-N 3.33Å; M457-V459 PolarHBondContact O-N 3.32Å; M457-G460 PolarHBondContact O-N 3.26Å; M457-G460 VanDerWaalsContact O-N 3.16Å; M457-L461 HydrophobicContact CE-CD1 4.25Å; M457-L461 HydrophobicContact CG-CD1 4.15Å; M457-L461 PolarHBondContact O-N 2.91Å
458	S	94.4	Very high	94.5	Very high	26 Å²	26	29.3 Å²	29.3	18%	0.182	17%	0.167	C	C	.	.	H	α-helix	trans	-64.4	-36.4	-177.7	-57.6	0	0	0	0	112.9	L116 L454 F455 L461 M462	L116-S458 VanDerWaalsContact CD2-CB 3.43Å; L454-S458 PolarHBondContact O-N 3.45Å; L454-S458 PolarHBondContact O-OG 3.21Å; L454-S458 VanDerWaalsContact O-OG 3.08Å; F455-S458 PolarHBondContact O-N 2.81Å; S458-L461 PolarHBondContact O-N 3.21Å; S458-M462 WeakPolarHBondContact O-CB 3.35Å; S458-M462 PolarHBondContact O-N 3.18Å
459	V	95	Very high	94.2	Very high	33 Å²	33	32 Å²	32	20%	0.2	19%	0.189	C	C	.	.	H	α-helix	trans	-63.4	-44.4	173	171.1	0	0	0	0	110.9	V313 F455 Y456 M457 M462 L463	V313-V459 HydrophobicContact CG1-CG1 4.49Å; V313-V459 HydrophobicContact CG2-CB 4.43Å; V313-V459 HydrophobicContact CG2-CG1 4.32Å; F455-V459 HydrophobicContact CD1-CG2 4.21Å; F455-V459 HydrophobicContact CE1-CG2 3.77Å; F455-V459 HydrophobicContact CE2-CG2 4.44Å; F455-V459 HydrophobicContact CZ-CG2 3.9Å; F455-V459 WeakPolarHBondContact O-CG2 3.33Å; F455-V459 PolarHBondContact O-N 3.01Å; Y456-V459 PolarHBondContact O-N 3.39Å; M457-V459 VanDerWaalsContact C-N 3.33Å; M457-V459 PolarHBondContact O-N 3.32Å; V459-M462 PolarHBondContact O-N 3.14Å; V459-L463 HydrophobicContact CG1-CD1 3.75Å; V459-L463 HydrophobicContact CG1-CG 4.27Å; V459-L463 WeakPolarHBondContact O-CB 3.4Å; V459-L463 WeakPolarHBondContact O-CG 3.41Å; V459-L463 PolarHBondContact O-N 3Å
460	G	96.5	Very high	93.7	Very high	0 Å²	0	37 Å²	37	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-58.9	-48.2	175.7	0	0	0	0	0	112.4	V313 F317 Y456 M457 M462 L463 G464	V313-G460 WeakPolarHBondContact O-CA 3.47Å; F317-G460 VanDerWaalsContact CA-O 3.24Å; F317-G460 WeakPolarHBondContact CA-O 3.41Å; F317-G460 PolarHBondContact N-O 3.4Å; Y456-G460 PolarHBondContact O-N 3.08Å; M457-G460 PolarHBondContact O-N 3.26Å; M457-G460 VanDerWaalsContact O-N 3.16Å; G460-M462 PolarHBondContact O-N 3.03Å; G460-L463 PolarHBondContact O-N 3.48Å; G460-G464 PolarHBondContact O-N 3.27Å
461	L	94.1	Very high	93.2	Very high	64 Å²	64	38.9 Å²	38.9	34%	0.335	22%	0.224	S	C	.	.	H	α-helix	trans	-57.7	-49.6	176.2	-72.1	172.7	0	0	0	111.7	Y316 A320 M457 S458 G464 S465	Y316-L461 HydrophobicContact CD1-CD2 3.82Å; Y316-L461 HydrophobicContact CD1-CG 4.04Å; Y316-L461 HydrophobicContact CG-CD2 4.45Å; Y316-L461 HydrophobicContact CG-CG 4.37Å; A320-L461 HydrophobicContact CB-CD2 4.04Å; A320-L461 WeakPolarHBondContact CB-O 3.33Å; M457-L461 HydrophobicContact CE-CD1 4.25Å; M457-L461 HydrophobicContact CG-CD1 4.15Å; M457-L461 PolarHBondContact O-N 2.91Å; S458-L461 PolarHBondContact O-N 3.21Å; L461-G464 PolarHBondContact O-N 3.46Å; L461-S465 WeakPolarHBondContact O-CB 3.37Å; L461-S465 PolarHBondContact O-N 2.95Å; L461-S465 PolarHBondContact O-OG 2.84Å; L461-S465 VanDerWaalsContact O-OG 3.09Å
462	M	91.8	Very high	92.4	Very high	82 Å²	82	42.2 Å²	42.2	40%	0.404	24%	0.24	S	C	.	.	H	α-helix	trans	-61.2	-48.4	-178.6	-177.2	-173.4	73.3	0	0	112	L116 S458 V459 G460 A466	L116-M462 HydrophobicContact CD1-SD 3.69Å; S458-M462 WeakPolarHBondContact O-CB 3.35Å; S458-M462 PolarHBondContact O-N 3.18Å; V459-M462 PolarHBondContact O-N 3.14Å; G460-M462 PolarHBondContact O-N 3.03Å; M462-A466 VanDerWaalsContact O-CB 3.29Å; M462-A466 WeakPolarHBondContact O-CB 3.37Å; M462-A466 PolarHBondContact O-N 2.93Å
463	L	94.3	Very high	91.5	Very high	74 Å²	74	49.5 Å²	49.5	39%	0.387	27%	0.273	S	S	.	.	H	α-helix	trans	-65.6	-41.9	-179.6	-69.6	175.3	0	0	0	111.5	F317 V459 G460 A466 C467	F317-L463 HydrophobicContact CD2-CB 3.72Å; F317-L463 HydrophobicContact CE2-CB 4.07Å; V459-L463 HydrophobicContact CG1-CD1 3.75Å; V459-L463 HydrophobicContact CG1-CG 4.27Å; V459-L463 WeakPolarHBondContact O-CB 3.4Å; V459-L463 WeakPolarHBondContact O-CG 3.41Å; V459-L463 PolarHBondContact O-N 3Å; G460-L463 PolarHBondContact O-N 3.48Å; L463-A466 PolarHBondContact O-N 3.1Å; L463-C467 WeakPolarHBondContact O-CB 3.45Å; L463-C467 PolarHBondContact O-N 3.45Å; L463-C467 PolarHBondContact O-SG 3.38Å
464	G	95.2	Very high	90.4	Very high	0 Å²	0	56.5 Å²	56.5	0%	0	30%	0.304	C	S	.	.	H	α-helix	trans	-61.1	-49.6	177.5	0	0	0	0	0	111.8	G460 L461 C467 A468	G460-G464 PolarHBondContact O-N 3.27Å; L461-G464 PolarHBondContact O-N 3.46Å; G464-C467 PolarHBondContact O-N 3.34Å; G464-A468 WeakPolarHBondContact O-CB 3.45Å; G464-A468 PolarHBondContact O-N 3.26Å
465	S	91.2	Very high	89.1	Confident	60 Å²	60	57.9 Å²	57.9	42%	0.42	31%	0.311	S	S	.	.	H	α-helix	trans	-63.5	-41.6	177.9	-60.8	0	0	0	0	112.7	L461 A468 A469	L461-S465 WeakPolarHBondContact O-CB 3.37Å; L461-S465 PolarHBondContact O-N 2.95Å; L461-S465 PolarHBondContact O-OG 2.84Å; L461-S465 VanDerWaalsContact O-OG 3.09Å; S465-A468 PolarHBondContact O-N 3.02Å; S465-A469 PolarHBondContact O-N 2.92Å
466	A	90.1	Very high	88.8	Confident	50 Å²	50	56.9 Å²	56.9	41%	0.413	31%	0.309	S	S	.	.	H	α-helix	trans	-63.6	-44.4	177.9	0	0	0	0	0	111.7	M462 L463 A468 A469 L470	M462-A466 VanDerWaalsContact O-CB 3.29Å; M462-A466 WeakPolarHBondContact O-CB 3.37Å; M462-A466 PolarHBondContact O-N 2.93Å; L463-A466 PolarHBondContact O-N 3.1Å; A466-A468 VanDerWaalsContact C-N 3.33Å; A466-A469 PolarHBondContact O-N 2.65Å; A466-L470 WeakPolarHBondContact O-CG 3.41Å; A466-L470 PolarHBondContact O-N 3.45Å; A466-L470 VanDerWaalsContact O-N 3.08Å
467	C	93.4	Very high	88.4	Confident	47 Å²	47	57.9 Å²	57.9	32%	0.318	32%	0.318	S	S	.	.	H	α-helix	trans	-68	-33	176.6	-68.3	0	0	0	0	112.2	F317 F321 L463 G464 L471	F317-C467 HydrophobicContact CE2-CB 4.16Å; F317-C467 HydrophobicContact CZ-CB 4.09Å; F321-C467 HydrophobicContact CD2-CB 3.67Å; F321-C467 HydrophobicContact CE2-CB 3.57Å; L463-C467 WeakPolarHBondContact O-CB 3.45Å; L463-C467 PolarHBondContact O-N 3.45Å; L463-C467 PolarHBondContact O-SG 3.38Å; G464-C467 PolarHBondContact O-N 3.34Å; C467-L471 WeakPolarHBondContact O-CB 3.28Å; C467-L471 PolarHBondContact O-N 3.35Å
468	A	91.4	Very high	88	Confident	2 Å²	2	58.9 Å²	58.9	2%	0.017	33%	0.325	C	S	.	.	H	α-helix	trans	-65.8	-45.6	174.3	0	0	0	0	0	112.2	F321 A325 G464 S465 A466 L470 L471 E472	F321-A468 HydrophobicContact CD2-CB 4.32Å; A325-A468 HydrophobicContact CB-CB 3.66Å; G464-A468 WeakPolarHBondContact O-CB 3.45Å; G464-A468 PolarHBondContact O-N 3.26Å; S465-A468 PolarHBondContact O-N 3.02Å; A466-A468 VanDerWaalsContact C-N 3.33Å; A468-L470 VanDerWaalsContact C-N 3.3Å; A468-L470 PolarHBondContact O-N 3.07Å; A468-L471 WeakPolarHBondContact O-CB 3.44Å; A468-L471 PolarHBondContact O-N 3.21Å; A468-L471 VanDerWaalsContact O-N 3.09Å; A468-E472 PolarHBondContact O-N 3.17Å
469	A	86.5	Confident	87.6	Confident	58 Å²	58	60.9 Å²	60.9	48%	0.479	33%	0.333	S	S	.	.	H	α-helix	trans	-61.8	-38.8	176.7	0	0	0	0	0	112	S465 A466 H473	S465-A469 PolarHBondContact O-N 2.92Å; A466-A469 PolarHBondContact O-N 2.65Å; A469-H473 PolarHBondContact O-N 2.95Å
470	L	87.1	Confident	87.1	Confident	104 Å²	104	62.6 Å²	62.6	55%	0.545	34%	0.342	S	S	.	.	H	α-helix	trans	-62.8	-43.6	172.1	-72.4	172.1	0	0	0	111.4	A466 A468 H473 F474	A466-L470 WeakPolarHBondContact O-CG 3.41Å; A466-L470 PolarHBondContact O-N 3.45Å; A466-L470 VanDerWaalsContact O-N 3.08Å; A468-L470 VanDerWaalsContact C-N 3.3Å; A468-L470 PolarHBondContact O-N 3.07Å; L470-H473 WeakPolarHBondContact O-CB 3.35Å; L470-H473 PolarHBondContact O-N 3.02Å; L470-H473 VanDerWaalsContact O-N 3.15Å; L470-F474 WeakPolarHBondContact O-CD2 3.39Å; L470-F474 PolarHBondContact O-N 2.89Å
471	L	84.8	Confident	86.5	Confident	45 Å²	45	66.8 Å²	66.8	24%	0.236	36%	0.364	C	S	.	.	H	α-helix	trans	-61.4	-46.5	179.1	-175.4	71.4	0	0	0	111.5	F321 I326 L394 C467 A468 H473 F474 I475	F321-L471 HydrophobicContact CE1-CD2 3.93Å; F321-L471 HydrophobicContact CZ-CB 4.32Å; F321-L471 HydrophobicContact CZ-CD2 3.73Å; I326-L471 HydrophobicContact CD1-CD2 3.95Å; I326-L471 HydrophobicContact CG1-CD2 4.38Å; L394-L471 HydrophobicContact CD2-CD2 4.1Å; C467-L471 WeakPolarHBondContact O-CB 3.28Å; C467-L471 PolarHBondContact O-N 3.35Å; A468-L471 WeakPolarHBondContact O-CB 3.44Å; A468-L471 PolarHBondContact O-N 3.21Å; A468-L471 VanDerWaalsContact O-N 3.09Å; L471-H473 PolarHBondContact O-N 3.25Å; L471-F474 PolarHBondContact O-N 3.18Å; L471-I475 HydrophobicContact CD1-CD1 3.74Å; L471-I475 HydrophobicContact CD1-CG1 4.07Å; L471-I475 HydrophobicContact CD2-CD1 3.8Å; L471-I475 HydrophobicContact CG-CD1 3.48Å; L471-I475 VanDerWaalsContact CG-CD1 3.48Å; L471-I475 HydrophobicContact CG-CG1 4.09Å; L471-I475 WeakPolarHBondContact O-CG1 3.27Å; L471-I475 PolarHBondContact O-N 3.04Å
472	E	78.2	Confident	86	Confident	72 Å²	72	67 Å²	67	34%	0.336	37%	0.366	S	S	.	.	H	α-helix	trans	-61.4	-21.7	176.3	-72.6	-172.9	156	0	0	113.5	A325 N329 A468	A325-E472 WeakPolarHBondContact CA-OE1 3.37Å; A325-E472 HydrophobicContact CB-CG 4.38Å; A325-E472 VanDerWaalsContact CB-OE1 3.29Å; A325-E472 WeakPolarHBondContact CB-OE1 3.5Å; N329-E472 PolarHBondContact ND2-OE1 3.05Å; A468-E472 PolarHBondContact O-N 3.17Å
473	H	77.6	Confident	85.5	Confident	159 Å²	159	65.8 Å²	65.8	74%	0.736	36%	0.363	S	S	*	.	H	α-helix	trans	-80	-22	173.5	-163.7	64.9	0	0	0	112.9	A469 L470 L471	A469-H473 PolarHBondContact O-N 2.95Å; L470-H473 WeakPolarHBondContact O-CB 3.35Å; L470-H473 PolarHBondContact O-N 3.02Å; L470-H473 VanDerWaalsContact O-N 3.15Å; L471-H473 PolarHBondContact O-N 3.25Å
474	F	74.4	Confident	84.8	Confident	148 Å²	148	65.2 Å²	65.2	65%	0.649	36%	0.361	S	S	*	.	H	α-helix	trans	-100.9	-11.3	-178.7	-71	-64.1	0	0	0	114.2	H403 L470 L471	H403-F474 PolarHBondContact CD2-O 3.26Å; L470-F474 WeakPolarHBondContact O-CD2 3.39Å; L470-F474 PolarHBondContact O-N 2.89Å; L471-F474 PolarHBondContact O-N 3.18Å
475	I	67.6	Low	83.8	Confident	37 Å²	37	71.1 Å²	71.1	19%	0.19	39%	0.394	C	S	.	.			trans	-111.1	0	172.9	-44.4	170.4	0	0	0	108.1	L394 Y398 S402 L404 L471	L394-I475 HydrophobicContact CD2-CD1 4.23Å; Y398-I475 HydrophobicContact CE1-CG2 4.32Å; S402-I475 VanDerWaalsContact CB-O 3.31Å; S402-I475 WeakPolarHBondContact CB-O 3.3Å; S402-I475 PolarHBondContact OG-O 3.33Å; L404-I475 HydrophobicContact CD1-CD1 4.05Å; L404-I475 HydrophobicContact CD1-CG2 4.22Å; L471-I475 HydrophobicContact CD1-CD1 3.74Å; L471-I475 HydrophobicContact CD1-CG1 4.07Å; L471-I475 HydrophobicContact CD2-CD1 3.8Å; L471-I475 HydrophobicContact CG-CD1 3.48Å; L471-I475 VanDerWaalsContact CG-CD1 3.48Å; L471-I475 HydrophobicContact CG-CG1 4.09Å; L471-I475 WeakPolarHBondContact O-CG1 3.27Å; L471-I475 PolarHBondContact O-N 3.04Å

Retrieved 475 of 475 residues in 1398.2 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).