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Isoform B of Reticulon-4 AlphaSync

Mainly function in endothelial cells and vascular smooth muscle cells, is also involved in immune system regulation (Probable). Modulator of vascular remodeling, promotes the migration of endothelial cells but inhibits the migration of vascular smooth muscle cells¹. Regulates endothelial sphingolipid biosynthesis with direct effects on vascular function and blood pressure. Inhibits serine palmitoyltransferase, SPTLC1, the rate-limiting enzyme of the novo sphingolipid biosynthetic pathway, thereby controlling production of endothelial sphingosine-1-phosphate (S1P)². Required to promote macrophage homing and functions such as cytokine/chemokine gene expression involved in angiogenesis, arteriogenesis and tissue repair³. Mediates ICAM1 induced transendothelial migration of leukocytes such as monocytes and neutrophils and acute inflammation⁴. Necessary for immune responses triggered by nucleic acid sensing TLRs, such as TLR9, is required for proper TLR9 location to endolysosomes⁵. Also involved in immune response to LPS⁶. Plays a role in liver regeneration through the modulation of hepatocytes proliferation⁷. Reduces the anti-apoptotic activity of Bcl-xl and Bcl-2. This is likely consecutive to their change in subcellular location, from the mitochondria to the endoplasmic reticulum, after binding and sequestration. With isoform C, inhibits BACE1 activity and amyloid precursor protein processing (By similarity).

AlphaFold DB , UniProt , Accession Q99P72-5 (canonical: Q99P72), Species MOUSE (Mus musculus, Mouse), Gene Rtn4, Length 356 aa.

Structure Viewer

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(Predicted Aligned Error values between residue pairs)

Download Structure AlphaSync Parameters PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	48.8	Very low	42.5	Very low	211 Å²	211	150.8 Å²	150.8	100%	1.039	84%	0.835	S	S	*	*				0	90.7	0	-118.7	141.8	179.7	0	0	105
2	E	43.2	Very low	41.9	Very low	138 Å²	138	147.2 Å²	147.2	65%	0.645	83%	0.828	S	S	*	*				79.3	135.1	93.8	-71.2	168.2	170.2	0	0	106.5
3	D	51.8	Low	41.1	Very low	160 Å²	160	144.4 Å²	144.4	86%	0.856	82%	0.824	S	S	*	*				-141.8	125.9	59.7	-67.6	-61.6	0	0	0	113.5
4	I	49.5	Very low	40.4	Very low	147 Å²	147	141 Å²	141	75%	0.754	82%	0.822	S	S	*	*			trans	-77	128.6	160.8	-95.5	157	0	0	0	106.5
5	D	48.9	Very low	40	Very low	145 Å²	145	141.3 Å²	141.3	78%	0.775	82%	0.82	S	S	*	*			trans	170.9	98.8	142.7	-90.5	-28.2	0	0	0	111.7
6	Q	41.3	Very low	39.5	Very low	191 Å²	191	138.5 Å²	138.5	89%	0.893	81%	0.81	S	S	*	*				171.4	132.6	105.2	-98.4	-179.7	44.1	0	0	112.7
7	S	38.5	Very low	40.2	Very low	109 Å²	109	137.3 Å²	137.3	76%	0.762	81%	0.808	S	S	*	*			trans	-84	144	172.4	48	0	0	0	0	113.3
8	S	37.9	Very low	40.4	Very low	127 Å²	127	136.8 Å²	136.8	89%	0.888	81%	0.809	S	S	*	*				-175.2	149.5	128.4	50.6	0	0	0	0	112.2
9	L	35.8	Very low	40.4	Very low	170 Å²	170	141.5 Å²	141.5	89%	0.89	81%	0.812	S	S	*	*			trans	-86	138.4	-168.4	-66.1	153.2	0	0	0	112.5
10	V	38.9	Very low	40.9	Very low	151 Å²	151	140.7 Å²	140.7	92%	0.915	81%	0.812	S	S	*	*			trans	-141.4	138	134.6	164.5	0	0	0	0	108.4
11	S	33.4	Very low	41.1	Very low	110 Å²	110	139.2 Å²	139.2	77%	0.769	81%	0.807	S	S	*	*			trans	-78.3	154.2	-162.8	-161.7	0	0	0	0	115
12	S	34.9	Very low	41.3	Very low	107 Å²	107	133.7 Å²	133.7	75%	0.748	79%	0.787	S	S	*	*				123.8	107.3	125.5	-151.6	0	0	0	0	115.5
13	S	31.6	Very low	41.1	Very low	111 Å²	111	132 Å²	132	78%	0.776	80%	0.797	S	S	*	*			trans	-26.3	153.8	154.1	-51.5	0	0	0	0	117.7
14	A	31.8	Very low	40.7	Very low	97 Å²	97	133 Å²	133	80%	0.802	79%	0.793	S	S	*	*			trans	94	113.3	142.4	0	0	0	0	0	117.8
15	D	33.4	Very low	39.9	Very low	146 Å²	146	135.2 Å²	135.2	78%	0.781	80%	0.798	S	S	*	*				116.5	111	123.9	-156.1	28.2	0	0	0	117.5
16	S	32.2	Very low	39.9	Very low	96 Å²	96	139.4 Å²	139.4	67%	0.671	80%	0.804	S	S	*	*			trans	71.9	167.1	145.8	-74.4	0	0	0	0	120.7
17	P	52	Low	39.5	Very low	118 Å²	118	138 Å²	138	77%	0.766	80%	0.798	S	S	*	*			cis	-134.4	-168.1	-43.6	41.4	-23.7	0	0	0	111.4
18	P	44.1	Very low	39.2	Very low	128 Å²	128	140.7 Å²	140.7	83%	0.831	80%	0.796	S	S	*	*			trans	-95.3	149.9	-161.7	37.3	-31.8	0	0	0	115.3
19	R	39.4	Very low	39.5	Very low	227 Å²	227	141.5 Å²	141.5	86%	0.857	80%	0.795	S	S	*	*			trans	-156.5	127.4	159.6	-175.3	178.6	-68.9	-144.4	-0.5	110.8
20	P	51.4	Low	39.3	Very low	125 Å²	125	138 Å²	138	81%	0.812	78%	0.781	S	S	*	*			trans	-96	137.7	174.3	34	-28.1	0	0	0	112.2
21	P	45.2	Very low	39.3	Very low	110 Å²	110	139 Å²	139	71%	0.714	78%	0.776	S	S	*	*			trans	-144	-179.2	155	41.8	-25.9	0	0	0	112.6
22	P	51.4	Low	39.9	Very low	95 Å²	95	138.8 Å²	138.8	62%	0.617	77%	0.771	S	S	*	*				-127.5	170.8	-58.8	36.6	-21.4	0	0	0	112.2	F24	P22-F24 HydrophobicContact CG-CD2 4.25Å; P22-F24 HydrophobicContact CG-CE2 3.92Å; P22-F24 PolarHBondContact O-N 2.79Å
23	A	40.5	Very low	40	Very low	103 Å²	103	141.4 Å²	141.4	85%	0.851	77%	0.772	S	S	*	*			trans	-70.6	116.4	172.6	0	0	0	0	0	111.4
24	F	41.9	Very low	40.8	Very low	180 Å²	180	144 Å²	144	79%	0.789	78%	0.777	S	S	*	*			trans	-96.7	105.2	171.8	-93	-87.9	0	0	0	110.2	P22	P22-F24 HydrophobicContact CG-CD2 4.25Å; P22-F24 HydrophobicContact CG-CE2 3.92Å; P22-F24 PolarHBondContact O-N 2.79Å
25	K	34.6	Very low	41.4	Very low	194 Å²	194	147 Å²	147	84%	0.843	78%	0.775	S	S	*	*			trans	-86.3	120.2	172.5	-157.1	174	-172.9	-179.5	0	107.1	Q27	K25-Q27 PolarHBondContact O-N 3.48Å
26	Y	47.4	Very low	41.6	Very low	233 Å²	233	148.4 Å²	148.4	91%	0.914	78%	0.776	S	S	*	*			trans	-68.2	128.8	174	-88.1	-92.7	0	0	0	109.8
27	Q	32.8	Very low	42.5	Very low	162 Å²	162	152 Å²	152	76%	0.757	79%	0.788	S	S	*	*			trans	-120.2	120.8	-176.1	-164.2	162.3	-32.1	0	0	108.6	K25	K25-Q27 PolarHBondContact O-N 3.48Å
28	F	32.5	Very low	41.9	Very low	164 Å²	164	155.1 Å²	155.1	72%	0.719	79%	0.793	S	S	*	*			trans	55.9	125.7	149.1	-71.6	-118.3	0	0	0	120.4
29	V	45.4	Very low	41.7	Very low	145 Å²	145	157.5 Å²	157.5	88%	0.879	79%	0.793	S	S	*	*				-141.7	130.7	120.7	178.9	0	0	0	0	108.2
30	T	31.4	Very low	41.6	Very low	95 Å²	95	153.4 Å²	153.4	58%	0.583	79%	0.788	S	S	*	*			trans	-94.5	156.6	-177.3	-57.5	0	0	0	0	110.5
31	E	38.6	Very low	41.1	Very low	173 Å²	173	155.7 Å²	155.7	81%	0.808	79%	0.788	S	S	*	*			trans	147.9	149.3	137.4	-83.5	160.8	110.1	0	0	112.6
32	P	44.9	Very low	41.2	Very low	105 Å²	105	160.1 Å²	160.1	68%	0.682	80%	0.799	S	S	*	*			cis	-133.3	160.4	-45.9	35.6	-18.1	0	0	0	113.9
33	E	38.6	Very low	40.5	Very low	163 Å²	163	164.2 Å²	164.2	76%	0.762	81%	0.809	S	S	*	*			trans	16.6	120	141.8	-61.3	164.8	161	0	0	121.2
34	D	48	Very low	40.5	Very low	164 Å²	164	167.5 Å²	167.5	88%	0.877	81%	0.807	S	S	*	*			trans	-150.6	85.2	134.3	-76.2	-44.3	0	0	0	103.8
35	E	43.5	Very low	40.7	Very low	161 Å²	161	166.5 Å²	166.5	75%	0.752	81%	0.805	S	S	*	*				43.6	95.8	99.9	-67.7	-171	178.6	0	0	112.5
36	E	38.3	Very low	41.3	Very low	175 Å²	175	164.6 Å²	164.6	82%	0.818	80%	0.804	S	S	*	*				71.9	102.2	101.4	-76.8	-174.2	-170.2	0	0	113.1
37	D	50.9	Low	41.1	Very low	173 Å²	173	161.9 Å²	161.9	93%	0.925	81%	0.805	S	S	*	*			trans	-149.8	105.9	142.8	-84.7	-38.3	0	0	0	107
38	E	38.3	Very low	42	Very low	183 Å²	183	162.1 Å²	162.1	86%	0.855	81%	0.806	S	S	*	*			trans	-73.1	-174.7	161.2	-65.9	-179	153.2	0	0	109.7
39	E	41.1	Very low	42.7	Very low	178 Å²	178	162.2 Å²	162.2	83%	0.832	82%	0.815	S	S	*	*			trans	96.2	95.5	178.9	-55	-178.1	-173.5	0	0	113.7
40	D	37.2	Very low	43	Very low	140 Å²	140	163.4 Å²	163.4	75%	0.749	82%	0.815	S	S	*	*				95.8	125.2	64	-77.6	-30.5	0	0	0	112.5
41	E	39.8	Very low	43.7	Very low	174 Å²	174	167.5 Å²	167.5	81%	0.813	83%	0.828	S	S	*	*			trans	51.3	112.7	143.1	-58.8	-178.1	174.8	0	0	120.3
42	E	47.4	Very low	44.3	Very low	203 Å²	203	168.4 Å²	168.4	95%	0.949	83%	0.832	S	S	*	*				-145.5	100.6	125.9	-71.1	-161.6	168.4	0	0	109
43	E	36.5	Very low	44.3	Very low	180 Å²	180	171.8 Å²	171.8	84%	0.841	84%	0.843	S	S	*	*			trans	-75.8	165.5	150.7	-72.4	-174.2	157.8	0	0	109.3
44	E	40.8	Very low	45	Very low	172 Å²	172	172.6 Å²	172.6	80%	0.804	85%	0.847	S	S	*	*			trans	86.2	134.7	173.5	-46.6	-146.2	165.7	0	0	114.4
45	E	46	Very low	45.1	Very low	159 Å²	159	171.2 Å²	171.2	74%	0.743	84%	0.844	S	S	*	*			cis	-167.2	146.7	33.6	-136.5	166.9	-167.9	0	0	106
46	D	48.2	Very low	45.4	Very low	155 Å²	155	171.7 Å²	171.7	83%	0.829	85%	0.851	S	S	*	*			trans	178.5	59.8	148.4	-85.9	-22.9	0	0	0	108.8
47	D	42.8	Very low	45.6	Very low	175 Å²	175	172.2 Å²	172.2	94%	0.936	85%	0.854	S	S	*	*			trans	-98.4	67.1	158.9	-85.9	-34.8	0	0	0	108.1
48	E	51.5	Low	45.2	Very low	167 Å²	167	175.4 Å²	175.4	78%	0.78	85%	0.853	S	S	*	*			trans	-120.8	99	167.9	-69.8	-167.2	162.7	0	0	108.2
49	D	47.4	Very low	45.1	Very low	167 Å²	167	176.1 Å²	176.1	89%	0.893	85%	0.853	S	S	*	*	S	Bend	trans	178.7	15.3	152.4	-92.7	-22	0	0	0	115.1
50	L	50.8	Low	44.8	Very low	170 Å²	170	173.5 Å²	173.5	89%	0.89	85%	0.851	S	S	*	*	S	Bend	trans	-134.4	21.6	-179.1	-136	92.4	0	0	0	117.9
51	E	47.7	Very low	44.4	Very low	180 Å²	180	171.5 Å²	171.5	84%	0.841	85%	0.854	S	S	*	*	S	Bend	trans	-112.3	-1.9	172	-74.7	-160.2	158.1	0	0	115.9	L53	E51-L53 VanDerWaalsContact C-N 3.26Å; E51-L53 PolarHBondContact O-N 3.45Å
52	E	49.9	Very low	44.1	Very low	193 Å²	193	168.3 Å²	168.3	90%	0.902	86%	0.858	S	S	*	*	T	Hydrogen-bonded Turn	trans	-80.2	3.8	178.9	-145.7	-170.9	147.2	0	0	114.8
53	L	46.6	Very low	43.4	Very low	175 Å²	175	162.3 Å²	162.3	92%	0.916	85%	0.85	S	S	*	*	T	Hydrogen-bonded Turn	trans	-109.2	2.1	-176	-106.2	104.3	0	0	0	117.5	E51	E51-L53 VanDerWaalsContact C-N 3.26Å; E51-L53 PolarHBondContact O-N 3.45Å
54	E	53.4	Low	43.2	Very low	180 Å²	180	162 Å²	162	84%	0.841	85%	0.854	S	S	*	*	S	Bend	trans	-122.4	9.6	-178	-140.7	178.8	169.3	0	0	116.7
55	V	49	Very low	42.6	Very low	135 Å²	135	159.7 Å²	159.7	82%	0.818	86%	0.856	S	S	*	*	T	Hydrogen-bonded Turn	trans	-101	24.8	-176.8	-164.5	0	0	0	0	114.8
56	L	49.1	Very low	42	Very low	172 Å²	172	156.9 Å²	156.9	90%	0.901	86%	0.86	S	S	*	*	T	Hydrogen-bonded Turn	trans	-116	3.1	171.7	-101.2	168.4	0	0	0	116.6
57	E	42.2	Very low	41	Very low	186 Å²	186	153.9 Å²	153.9	87%	0.869	86%	0.857	S	S	*	*			trans	-114.8	64.6	175.1	-86.9	-107.9	105.6	0	0	112
58	R	44.2	Very low	40.5	Very low	240 Å²	240	151.1 Å²	151.1	91%	0.906	85%	0.849	S	S	*	*			trans	-136.7	92.3	156.4	-105.3	-169	175.5	96	-1.6	111.9	P60	R58-P60 WeakPolarHBondContact O-CD 3.36Å
59	K	34.5	Very low	39.8	Very low	198 Å²	198	149.5 Å²	149.5	86%	0.861	85%	0.85	S	S	*	*			trans	-70.3	114.2	158.6	175.6	175.2	178.2	171.9	0	109.3
60	P	35	Very low	40	Very low	123 Å²	123	146.8 Å²	146.8	80%	0.799	84%	0.841	S	S	*	*			trans	-87.6	127.2	165.9	23.1	-8.6	0	0	0	109.4	R58	R58-P60 WeakPolarHBondContact O-CD 3.36Å
61	A	30.4	Very low	39.1	Very low	98 Å²	98	144.4 Å²	144.4	81%	0.81	84%	0.836	S	S	*	*			trans	-87.4	118.3	165.3	0	0	0	0	0	109
62	A	33.4	Very low	38.5	Very low	107 Å²	107	140.2 Å²	140.2	88%	0.884	83%	0.832	S	S	*	*			trans	177.6	135.4	146	0	0	0	0	0	110.2
63	G	32	Very low	37.7	Very low	77 Å²	77	135.6 Å²	135.6	79%	0.794	83%	0.827	S	S	*	*			trans	124.8	80.1	158.7	0	0	0	0	0	115.4
64	L	31.5	Very low	37.2	Very low	174 Å²	174	131.9 Å²	131.9	91%	0.911	82%	0.821	S	S	*	*			trans	-61.4	150.8	156.9	-77.6	107.4	0	0	0	111
65	S	28.3	Very low	36.5	Very low	123 Å²	123	128.4 Å²	128.4	86%	0.86	82%	0.815	S	S	*	*			trans	91.1	93.4	158.4	-161.7	0	0	0	0	118
66	A	33.6	Very low	35.7	Very low	99 Å²	99	129 Å²	129	82%	0.818	81%	0.812	S	S	*	*				166.2	120.7	118.5	0	0	0	0	0	111.7
67	A	26.6	Very low	34.8	Very low	93 Å²	93	127.9 Å²	127.9	77%	0.769	81%	0.807	S	S	*	*			trans	-70.5	161.3	154	0	0	0	0	0	109.3
68	P	33	Very low	34.4	Very low	117 Å²	117	125.5 Å²	125.5	76%	0.76	80%	0.8	S	S	*	*			cis	-133.5	150.4	36.8	27.4	-3.2	0	0	0	115.5
69	V	37.2	Very low	33.7	Very low	133 Å²	133	123.5 Å²	123.5	81%	0.806	80%	0.798	S	S	*	*				51.5	153.7	96.6	-124	0	0	0	0	117.9
70	P	50.9	Low	33.7	Very low	109 Å²	109	118.8 Å²	118.8	71%	0.708	79%	0.79	S	S	*	*				-116.9	-167.6	-110.6	41	-20.5	0	0	0	113.5
71	P	32.8	Very low	33.4	Very low	121 Å²	121	118.2 Å²	118.2	79%	0.786	79%	0.789	S	S	*	*				-153.9	166.8	100.5	37.8	-18.6	0	0	0	117.8
72	A	35.6	Very low	33.4	Very low	92 Å²	92	120.8 Å²	120.8	76%	0.76	79%	0.789	S	S	*	*			trans	73.7	105.1	147.8	0	0	0	0	0	119
73	A	32.2	Very low	33.5	Very low	95 Å²	95	120.6 Å²	120.6	79%	0.785	78%	0.781	S	S	*	*				78.6	99.1	80.3	0	0	0	0	0	112.7
74	A	36	Very low	33.7	Very low	97 Å²	97	123.8 Å²	123.8	80%	0.802	79%	0.785	S	S	*	*				102.7	163.3	96.7	0	0	0	0	0	110.9
75	P	39	Very low	34.1	Very low	108 Å²	108	120.9 Å²	120.9	70%	0.701	78%	0.776	S	S	*	*				-137.8	-175.6	-99.1	42.4	-23.3	0	0	0	115.3
76	L	31	Very low	34.5	Very low	146 Å²	146	120.9 Å²	120.9	76%	0.764	77%	0.774	S	S	*	*			trans	63.7	114.9	152.5	-66.4	-175.4	0	0	0	121.1
77	L	31	Very low	34.7	Very low	150 Å²	150	120.6 Å²	120.6	79%	0.785	77%	0.771	S	S	*	*				39.8	111.2	125.9	-56.1	-177.7	0	0	0	119
78	D	33.6	Very low	35.5	Very low	135 Å²	135	122.4 Å²	122.4	72%	0.722	78%	0.775	S	S	*	*			trans	-151.1	106.4	135.1	-161	-12.3	0	0	0	109.7	S80	D78-S80 PolarHBondContact OD1-N 3.03Å; D78-S80 PolarHBondContact OD1-OG 3.48Å
79	F	29.4	Very low	35.8	Very low	199 Å²	199	129 Å²	129	87%	0.873	79%	0.785	S	S	*	*			trans	-96	90	164.8	-92	-86.8	0	0	0	106.8
80	S	34.3	Very low	35.9	Very low	98 Å²	98	125.9 Å²	125.9	69%	0.685	78%	0.78	S	S	*	*			trans	-123.1	92.2	167.1	-67	0	0	0	0	108.1	D78 D82	D78-S80 PolarHBondContact OD1-N 3.03Å; D78-S80 PolarHBondContact OD1-OG 3.48Å; S80-D82 PolarHBondContact O-N 2.88Å
81	S	30	Very low	35.4	Very low	112 Å²	112	127 Å²	127	78%	0.783	79%	0.787	S	S	*	*			trans	-69.9	113.6	162.8	-57.9	0	0	0	0	108.4
82	D	29.8	Very low	35.6	Very low	151 Å²	151	129.4 Å²	129.4	81%	0.807	79%	0.792	S	S	*	*			trans	-156.3	133.3	154.8	-127	-39.5	0	0	0	114.1	S80	S80-D82 PolarHBondContact O-N 2.88Å
83	S	34.6	Very low	35.8	Very low	104 Å²	104	130.9 Å²	130.9	73%	0.727	79%	0.794	S	S	*	*			trans	69.3	104	149.4	-73.8	0	0	0	0	121.1
84	V	37.8	Very low	36	Very low	143 Å²	143	131.5 Å²	131.5	87%	0.867	80%	0.799	S	S	*	*			trans	-129.8	139.5	144.8	176.7	0	0	0	0	109.1
85	P	38.9	Very low	36.2	Very low	113 Å²	113	131.4 Å²	131.4	73%	0.734	80%	0.798	S	S	*	*			trans	-114.1	-157.6	-151.8	46.5	-32.4	0	0	0	112.6
86	P	36.3	Very low	36.2	Very low	124 Å²	124	132 Å²	132	81%	0.805	80%	0.802	S	S	*	*				-120.1	169.8	-109.7	29.8	-7.1	0	0	0	116.1
87	A	38.3	Very low	36.7	Very low	92 Å²	92	131 Å²	131	76%	0.76	81%	0.805	S	S	*	*	P	Polyproline II helix	trans	-83	158.1	178.1	0	0	0	0	0	114.7
88	P	43.6	Very low	37	Very low	131 Å²	131	130.8 Å²	130.8	85%	0.851	81%	0.81	S	S	*	*	P	Polyproline II helix	trans	-86.6	142	-177.6	14.5	1.8	0	0	0	113.6
89	R	38.9	Very low	37.2	Very low	256 Å²	256	128.6 Å²	128.6	97%	0.966	81%	0.81	S	S	*	*	P	Polyproline II helix	trans	-78.8	135.9	-179.8	-66.5	172.3	170.7	141.8	-2.5	111.9
90	G	40	Very low	37.7	Very low	68 Å²	68	125 Å²	125	70%	0.701	81%	0.807	S	S	*	*			trans	-147.1	143.6	160.2	0	0	0	0	0	110.1
91	P	39.7	Very low	37.7	Very low	133 Å²	133	129.9 Å²	129.9	86%	0.864	82%	0.819	S	S	*	*	P	Polyproline II helix	trans	-98.5	142	-152.8	27.2	-14.4	0	0	0	114.6
92	L	37.1	Very low	38	Very low	170 Å²	170	136 Å²	136	89%	0.89	83%	0.825	S	S	*	*	P	Polyproline II helix	trans	-81.2	139.7	173.3	-68.8	168.7	0	0	0	111.5
93	P	40.2	Very low	38.1	Very low	124 Å²	124	137 Å²	137	81%	0.805	83%	0.825	S	S	*	*	P	Polyproline II helix	trans	-85.2	144.2	169.4	30.4	-25.8	0	0	0	112.2
94	A	35.8	Very low	38.4	Very low	107 Å²	107	137.4 Å²	137.4	88%	0.884	83%	0.825	S	S	*	*	P	Polyproline II helix	trans	-76.2	141.3	-175.1	0	0	0	0	0	113.9
95	A	40	Very low	38.1	Very low	95 Å²	95	135.8 Å²	135.8	79%	0.785	82%	0.82	S	S	*	*			trans	-138.7	148.9	156.5	0	0	0	0	0	109.9
96	P	39.8	Very low	37.6	Very low	121 Å²	121	142.5 Å²	142.5	79%	0.786	83%	0.831	S	S	*	*			trans	-97.9	175.7	-147.9	40.2	-35.2	0	0	0	114.1
97	P	41.1	Very low	37.3	Very low	126 Å²	126	145.8 Å²	145.8	82%	0.818	84%	0.835	S	S	*	*	P	Polyproline II helix	trans	-93.2	141.5	-140.9	35.6	-34.4	0	0	0	114.2
98	T	38.8	Very low	36.9	Very low	145 Å²	145	152.8 Å²	152.8	89%	0.89	84%	0.842	S	S	*	*	P	Polyproline II helix	trans	-85.4	128.4	163.6	-37.8	0	0	0	0	108.9
99	A	36	Very low	36.2	Very low	89 Å²	89	151.8 Å²	151.8	74%	0.736	84%	0.839	S	S	*	*	P	Polyproline II helix	trans	-64.2	157.5	-173.9	0	0	0	0	0	113.5
100	P	40.9	Very low	35.9	Very low	124 Å²	124	145.6 Å²	145.6	81%	0.805	83%	0.831	S	S	*	*	P	Polyproline II helix	trans	-88.7	135	-157.4	25.3	-16.8	0	0	0	114	R102	P100-R102 PolarHBondContact O-N 3.31Å
101	E	34	Very low	35.5	Very low	200 Å²	200	147 Å²	147	94%	0.935	84%	0.836	S	S	*	*			trans	-64.4	114.2	168.8	-155.1	179.8	117.7	0	0	109.7
102	R	36	Very low	35.2	Very low	239 Å²	239	145.1 Å²	145.1	90%	0.902	83%	0.832	S	S	*	*			trans	-96.9	115.3	179.6	-176.6	178	-85	167.3	-6.6	109.5	P100	P100-R102 PolarHBondContact O-N 3.31Å
103	Q	33	Very low	35.2	Very low	173 Å²	173	143.1 Å²	143.1	81%	0.808	83%	0.832	S	S	*	*			trans	-58.4	144.3	173.8	-69.6	174.4	-75.6	0	0	112.6	S105	Q103-S105 PolarHBondContact O-N 2.96Å
104	P	40.8	Very low	34.6	Very low	113 Å²	113	141.8 Å²	141.8	73%	0.734	83%	0.832	S	S	*	*			trans	-84.5	97.6	174.4	31.3	-29.3	0	0	0	110.6	W106	P104-W106 PolarHBondContact O-N 3.24Å
105	S	31	Very low	34.6	Very low	109 Å²	109	142.3 Å²	142.3	76%	0.762	83%	0.826	S	S	*	*			trans	-74.8	114.1	164.2	51.8	0	0	0	0	109.4	Q103 E107	Q103-S105 PolarHBondContact O-N 2.96Å; S105-E107 PolarHBondContact O-N 3.32Å
106	W	27.3	Very low	34.3	Very low	253 Å²	253	143.1 Å²	143.1	96%	0.958	83%	0.826	S	S	*	*			trans	-65.8	105.9	173.7	-71.7	72.4	0	0	0	110.1	P104	P104-W106 PolarHBondContact O-N 3.24Å
107	E	31.8	Very low	33.9	Very low	193 Å²	193	145.7 Å²	145.7	90%	0.902	83%	0.832	S	S	*	*			trans	-116.4	142.6	162.7	-95.7	-170	136.6	0	0	112	S105	S105-E107 PolarHBondContact O-N 3.32Å
108	R	28.3	Very low	33.9	Very low	239 Å²	239	145.2 Å²	145.2	90%	0.902	83%	0.829	S	S	*	*			trans	-80.3	141.6	-159.2	-178.2	177.4	-73.5	152.8	-4	111
109	S	29.1	Very low	33.7	Very low	111 Å²	111	144.3 Å²	144.3	78%	0.776	83%	0.826	S	S	*	*			trans	-38.9	141.6	172	-56.6	0	0	0	0	114.5
110	P	34.3	Very low	33.3	Very low	126 Å²	126	145 Å²	145	82%	0.818	83%	0.831	S	S	*	*			trans	-95.4	127.3	136.5	29.7	-18.4	0	0	0	109.3
111	A	30.9	Very low	33	Very low	96 Å²	96	144 Å²	144	79%	0.793	83%	0.834	S	S	*	*			trans	-65	164.5	162.8	0	0	0	0	0	110.8
112	A	33	Very low	32.9	Very low	95 Å²	95	139.1 Å²	139.1	79%	0.785	83%	0.827	S	S	*	*			trans	88.3	96.5	168.5	0	0	0	0	0	116.8
113	S	36.9	Very low	33	Very low	127 Å²	127	134.5 Å²	134.5	89%	0.888	83%	0.826	S	S	*	*				-175.1	92.7	115.4	-77.3	0	0	0	0	111
114	A	27.7	Very low	32.8	Very low	97 Å²	97	133.8 Å²	133.8	80%	0.802	83%	0.826	S	S	*	*			trans	-94.8	139.5	138.6	0	0	0	0	0	105.1
115	P	35.9	Very low	32.8	Very low	118 Å²	118	133.6 Å²	133.6	77%	0.766	83%	0.825	S	S	*	*				-139.2	166.5	59.2	29.1	-6.2	0	0	0	112.7
116	S	34.4	Very low	32.7	Very low	112 Å²	112	133.2 Å²	133.2	78%	0.783	82%	0.822	S	S	*	*				-178.1	123.2	91.8	-57.1	0	0	0	0	109.8
117	L	31.8	Very low	32.9	Very low	175 Å²	175	131 Å²	131	92%	0.916	82%	0.82	S	S	*	*	P	Polyproline II helix	trans	-85.1	136.3	164.2	-74.2	159.9	0	0	0	109
118	P	40.8	Very low	32.6	Very low	116 Å²	116	129.1 Å²	129.1	75%	0.753	82%	0.815	S	S	*	*	P	Polyproline II helix	trans	-88.3	152.2	164.5	33.7	-28.5	0	0	0	111.1
119	P	33.4	Very low	33	Very low	125 Å²	125	123 Å²	123	81%	0.812	81%	0.807	S	S	*	*	P	Polyproline II helix	trans	-92.8	164.5	-163.6	36.7	-34.8	0	0	0	114.2
120	A	27.5	Very low	33.1	Very low	104 Å²	104	125.5 Å²	125.5	86%	0.86	81%	0.806	S	S	*	*			trans	-36.2	130.4	169.8	0	0	0	0	0	115.6
121	A	35.1	Very low	32.8	Very low	103 Å²	103	126.6 Å²	126.6	85%	0.851	81%	0.805	S	S	*	*			trans	-119.3	112.7	151.6	0	0	0	0	0	108
122	A	32.1	Very low	33.2	Very low	97 Å²	97	129.9 Å²	129.9	80%	0.802	81%	0.809	S	S	*	*			trans	-73.4	130.4	175.8	0	0	0	0	0	110.7
123	V	37.5	Very low	33.1	Very low	143 Å²	143	133.3 Å²	133.3	87%	0.867	81%	0.809	S	S	*	*			trans	-144.1	93.4	154	-177.9	0	0	0	0	108.5
124	L	30	Very low	33.4	Very low	157 Å²	157	132.9 Å²	132.9	82%	0.822	80%	0.803	S	S	*	*			trans	-76.8	166.9	141.7	-81.9	161.8	0	0	0	107.5
125	P	40.4	Very low	34.4	Very low	109 Å²	109	133.6 Å²	133.6	71%	0.708	80%	0.8	S	S	*	*			cis	-147	171.6	24.9	39.7	-18.3	0	0	0	117.7
126	S	28	Very low	34.6	Very low	101 Å²	101	133 Å²	133	71%	0.706	81%	0.805	S	S	*	*			trans	55.3	121.3	138.6	-64.9	0	0	0	0	122
127	K	32	Very low	34.2	Very low	207 Å²	207	139.1 Å²	139.1	90%	0.9	81%	0.811	S	S	*	*				-151.4	115.5	123.3	-87.6	-126.7	175.1	-176.8	0	111.8
128	L	26.7	Very low	34.9	Very low	153 Å²	153	136.1 Å²	136.1	80%	0.801	80%	0.801	S	S	*	*			trans	-72	148.8	157.2	-79.6	142.2	0	0	0	110.1
129	P	36.2	Very low	34.9	Very low	112 Å²	112	136.3 Å²	136.3	73%	0.727	80%	0.803	S	S	*	*				-129.7	122.7	120.8	12	8.8	0	0	0	110.2
130	E	30.7	Very low	34.9	Very low	163 Å²	163	134.8 Å²	134.8	76%	0.762	80%	0.801	S	S	*	*				54.7	96.8	89.2	-74.9	179.1	103.5	0	0	111.7
131	D	28.8	Very low	35.6	Very low	148 Å²	148	136.2 Å²	136.2	79%	0.791	80%	0.801	S	S	*	*				87.5	107.5	89.6	-89.3	-53.5	0	0	0	112
132	D	39.3	Very low	35.5	Very low	166 Å²	166	136.3 Å²	136.3	89%	0.888	80%	0.802	S	S	*	*			trans	-166.2	119.5	144.5	-133.6	-74	0	0	0	110.2
133	E	31	Very low	35.6	Very low	166 Å²	166	135.1 Å²	135.1	78%	0.776	80%	0.8	S	S	*	*			trans	-103.8	140.3	172.5	163	173.3	108.8	0	0	106.6
134	P	41.9	Very low	35.3	Very low	119 Å²	119	132.7 Å²	132.7	77%	0.773	79%	0.794	S	S	*	*				-152.5	170.2	91.8	34.9	-11.2	0	0	0	118.3
135	P	49.4	Very low	35.6	Very low	112 Å²	112	130.8 Å²	130.8	73%	0.727	79%	0.794	S	S	*	*			trans	-109.2	156	-161.9	39	-28.2	0	0	0	113.7
136	A	39.2	Very low	35.9	Very low	106 Å²	106	131 Å²	131	88%	0.876	80%	0.796	S	S	*	*			trans	-161.5	107	157.3	0	0	0	0	0	112.1
137	R	26.8	Very low	36.2	Very low	240 Å²	240	134.5 Å²	134.5	91%	0.906	81%	0.806	S	S	*	*			trans	-106.6	132.4	158.5	176.1	-168.4	-69.8	-135.8	1.2	107.7
138	P	46	Very low	36.6	Very low	111 Å²	111	129.4 Å²	129.4	72%	0.721	80%	0.802	S	S	*	*			trans	-109.2	163	153.9	30.8	-17	0	0	0	111.8
139	P	40.7	Very low	36.9	Very low	120 Å²	120	131.1 Å²	131.1	78%	0.779	81%	0.806	S	S	*	*	P	Polyproline II helix	trans	-103.5	159	-153	37.1	-29.8	0	0	0	114.6
140	A	34.5	Very low	37.2	Very low	94 Å²	94	131.2 Å²	131.2	78%	0.777	81%	0.806	S	S	*	*	P	Polyproline II helix	trans	-75.2	142.1	169.4	0	0	0	0	0	111.4
141	P	40.7	Very low	37.8	Very low	133 Å²	133	128.3 Å²	128.3	86%	0.864	81%	0.81	S	S	*	*	P	Polyproline II helix	trans	-75.7	137	176.9	28	-30.7	0	0	0	112.3
142	A	33.9	Very low	38.4	Very low	105 Å²	105	125.6 Å²	125.6	87%	0.868	81%	0.808	S	S	*	*	P	Polyproline II helix	trans	-85.8	156.6	175	0	0	0	0	0	112.4
143	G	33.7	Very low	38.7	Very low	73 Å²	73	123.6 Å²	123.6	75%	0.753	80%	0.804	S	S	*	*			trans	152.6	84.1	172	0	0	0	0	0	108.6
144	A	31.9	Very low	39.5	Very low	92 Å²	92	121.2 Å²	121.2	76%	0.76	80%	0.804	S	S	*	*				62.5	102.9	51.2	0	0	0	0	0	113.8
145	S	35.9	Very low	39.5	Very low	117 Å²	117	121 Å²	121	82%	0.818	80%	0.804	S	S	*	*			trans	139.8	163.4	144.9	-61.4	0	0	0	0	112.7
146	P	47.4	Very low	39.5	Very low	114 Å²	114	122.1 Å²	122.1	74%	0.74	81%	0.81	S	S	*	*				-137.3	166.2	-78.6	37.3	-17.3	0	0	0	114.5
147	L	33	Very low	40	Very low	174 Å²	174	122.5 Å²	122.5	91%	0.911	80%	0.803	S	S	*	*			trans	50.7	109.3	138.8	-149.6	84.2	0	0	0	120.3
148	A	41.6	Very low	40.9	Very low	100 Å²	100	115.8 Å²	115.8	83%	0.826	80%	0.799	S	S	*	*			trans	176.4	95.1	133.8	0	0	0	0	0	112.5
149	E	33.1	Very low	41	Very low	189 Å²	189	114.6 Å²	114.6	88%	0.883	80%	0.799	S	S	*	*			trans	-77.9	157.2	141	-142.8	177.5	108.9	0	0	106.5
150	P	42.3	Very low	41.6	Very low	113 Å²	113	114.5 Å²	114.5	73%	0.734	80%	0.798	S	S	*	*			cis	-141.1	152.5	15.1	39.5	-20	0	0	0	116.4
151	A	43.5	Very low	42.2	Very low	102 Å²	102	118.8 Å²	118.8	84%	0.843	80%	0.799	S	S	*	*			trans	-174.3	114.8	141.9	0	0	0	0	0	110.6
152	A	41	Very low	42.6	Very low	91 Å²	91	123.9 Å²	123.9	75%	0.752	80%	0.801	S	S	*	*			trans	-2.8	141.1	167.7	0	0	0	0	0	120.6	P154	A152-P154 WeakPolarHBondContact O-CD 3.38Å
153	P	44.5	Very low	43.5	Very low	124 Å²	124	127.1 Å²	127.1	81%	0.805	79%	0.791	S	S	*	*			trans	-75.2	126.6	-171.3	31.7	-33.4	0	0	0	112	S155	P153-S155 PolarHBondContact O-N 2.8Å
154	P	48.9	Very low	44.5	Very low	117 Å²	117	125.7 Å²	125.7	76%	0.76	78%	0.776	S	S	*	*			trans	-80.7	111.1	160.1	30.1	-25.9	0	0	0	108	A152 T156	A152-P154 WeakPolarHBondContact O-CD 3.38Å; P154-T156 PolarHBondContact O-N 3.41Å; P154-T156 VanDerWaalsContact O-N 3.11Å
155	S	42.2	Very low	45.9	Very low	113 Å²	113	126.1 Å²	126.1	79%	0.79	77%	0.774	S	S	*	*			trans	1.6	95	156.9	-52.7	0	0	0	0	115.1	P153 P157	P153-S155 PolarHBondContact O-N 2.8Å; S155-P157 VanDerWaalsContact O-CD 3.26Å; S155-P157 WeakPolarHBondContact O-CD 3.34Å
156	T	49.6	Very low	47.3	Very low	137 Å²	137	122.7 Å²	122.7	84%	0.84	76%	0.757	S	S	*	*			trans	-66.9	116.6	167.4	-29.5	0	0	0	0	107.3	P154 A158	P154-T156 PolarHBondContact O-N 3.41Å; P154-T156 VanDerWaalsContact O-N 3.11Å; T156-A158 PolarHBondContact O-N 3.42Å
157	P	48.9	Very low	48.7	Very low	113 Å²	113	119.3 Å²	119.3	73%	0.734	74%	0.736	S	S	*	*			trans	-64.2	130.8	-178.1	-14	28	0	0	0	108.1	S155 A159	S155-P157 VanDerWaalsContact O-CD 3.26Å; S155-P157 WeakPolarHBondContact O-CD 3.34Å; P157-A159 PolarHBondContact O-N 3.49Å
158	A	46.3	Very low	50.9	Low	99 Å²	99	114.8 Å²	114.8	82%	0.818	72%	0.715	S	S	*	*			trans	-46.5	108.5	174.1	0	0	0	0	0	109.4	T156	T156-A158 PolarHBondContact O-N 3.42Å
159	A	48.2	Very low	52.7	Low	87 Å²	87	114.4 Å²	114.4	72%	0.719	70%	0.702	S	S	*	*			trans	-53.5	128.6	175.6	0	0	0	0	0	108	P157 K161	P157-A159 PolarHBondContact O-N 3.49Å; A159-K161 PolarHBondContact O-N 3.07Å
160	P	52.1	Low	55.1	Low	117 Å²	117	108.9 Å²	108.9	76%	0.76	68%	0.681	S	S	*	*			trans	-64.2	111.3	-178.8	24.9	-30.3	0	0	0	107	R162	P160-R162 PolarHBondContact O-N 3.28Å
161	K	48	Very low	57.1	Low	185 Å²	185	104.9 Å²	104.9	80%	0.804	65%	0.654	S	S	*	*			trans	-58.7	92.8	174	-166.3	165.8	-174.8	172.2	0	106.5	A159 R163	A159-K161 PolarHBondContact O-N 3.07Å; K161-R163 PolarHBondContact O-N 2.98Å
162	R	49.1	Very low	59	Low	240 Å²	240	101.9 Å²	101.9	91%	0.906	62%	0.623	S	S	*	*			trans	-58.8	87.8	168.9	-78.1	-173.9	175	-160.3	-0.6	106	P160 G164	P160-R162 PolarHBondContact O-N 3.28Å; R162-G164 PolarHBondContact O-N 2.95Å
163	R	51.9	Low	61	Low	173 Å²	173	99.2 Å²	99.2	65%	0.653	60%	0.596	S	S	*	*			trans	-67.1	84.4	164.7	-69	-172	-167.7	-127	8.7	104.9	K161	K161-R163 PolarHBondContact O-N 2.98Å
164	G	54.5	Low	62.7	Low	43 Å²	43	97.6 Å²	97.6	44%	0.443	58%	0.575	S	S	.	*			trans	-53	146.3	171.3	0	0	0	0	0	108.2	R162 G166 S167	R162-G164 PolarHBondContact O-N 2.95Å; G164-G166 PolarHBondContact O-N 3.31Å; G164-S167 WeakPolarHBondContact O-CA 3.25Å; G164-S167 WeakPolarHBondContact O-CB 3.35Å; G164-S167 PolarHBondContact O-N 2.84Å
165	S	62	Low	64.4	Low	101 Å²	101	95.9 Å²	95.9	71%	0.706	55%	0.553	S	S	*	*	H	α-helix	trans	-47.1	-30.7	177.1	48.2	0	0	0	0	113.4	S167 V168 V169	S165-S167 VanDerWaalsContact C-N 3.29Å; S165-S167 PolarHBondContact O-N 3.45Å; S165-V168 PolarHBondContact O-N 3.21Å; S165-V169 PolarHBondContact O-N 3.37Å
166	G	65.8	Low	66.5	Low	45 Å²	45	98.6 Å²	98.6	46%	0.464	55%	0.546	S	S	.	.	H	α-helix	trans	-57.8	-34.8	171.6	0	0	0	0	0	114.2	G164 V168 V169 V170	G164-G166 PolarHBondContact O-N 3.31Å; G166-V168 VanDerWaalsContact C-N 3.29Å; G166-V168 PolarHBondContact O-N 3.38Å; G166-V169 PolarHBondContact O-N 2.87Å; G166-V170 VanDerWaalsContact O-CB 3.28Å; G166-V170 WeakPolarHBondContact O-CB 3.33Å; G166-V170 WeakPolarHBondContact O-CG2 3.31Å; G166-V170 PolarHBondContact O-N 3.47Å
167	S	76.8	Confident	68.2	Low	43 Å²	43	95.5 Å²	95.5	30%	0.301	52%	0.524	S	S	.	.	H	α-helix	trans	-60.6	-40.1	173.3	-174.8	0	0	0	0	111	G164 S165 D171	G164-S167 WeakPolarHBondContact O-CA 3.25Å; G164-S167 WeakPolarHBondContact O-CB 3.35Å; G164-S167 PolarHBondContact O-N 2.84Å; S165-S167 VanDerWaalsContact C-N 3.29Å; S165-S167 PolarHBondContact O-N 3.45Å; S167-D171 WeakPolarHBondContact O-CB 3.47Å; S167-D171 PolarHBondContact O-N 3Å; S167-D171 PolarHBondContact OG-OD2 3.49Å
168	V	78.2	Confident	69.9	Low	79 Å²	79	95.8 Å²	95.8	48%	0.479	52%	0.519	S	S	.	.	H	α-helix	trans	-69.3	-46.9	-177.8	-179.1	0	0	0	0	110.1	S165 G166 V170 D171 L172	S165-V168 PolarHBondContact O-N 3.21Å; G166-V168 VanDerWaalsContact C-N 3.29Å; G166-V168 PolarHBondContact O-N 3.38Å; V168-V170 VanDerWaalsContact C-N 3.32Å; V168-V170 PolarHBondContact O-N 2.95Å; V168-D171 PolarHBondContact O-N 2.89Å; V168-L172 HydrophobicContact CG1-CD1 3.71Å; V168-L172 WeakPolarHBondContact O-CD1 3.38Å; V168-L172 PolarHBondContact O-N 2.93Å
169	V	79.8	Confident	71.9	Confident	92 Å²	92	99.9 Å²	99.9	56%	0.558	52%	0.518	S	S	*	.	H	α-helix	trans	-62.1	-41.9	177.7	-179.1	0	0	0	0	111.2	S165 G166 L172 L173	S165-V169 PolarHBondContact O-N 3.37Å; G166-V169 PolarHBondContact O-N 2.87Å; V169-L172 WeakPolarHBondContact O-CB 3.33Å; V169-L172 PolarHBondContact O-N 2.88Å; V169-L173 PolarHBondContact O-N 3.44Å
170	V	82.8	Confident	73.8	Confident	72 Å²	72	101.6 Å²	101.6	44%	0.436	51%	0.509	S	S	.	.	H	α-helix	trans	-65.2	-42.7	175.3	172	0	0	0	0	110.9	G166 V168 L172 L173 Y174	G166-V170 VanDerWaalsContact O-CB 3.28Å; G166-V170 WeakPolarHBondContact O-CB 3.33Å; G166-V170 WeakPolarHBondContact O-CG2 3.31Å; G166-V170 PolarHBondContact O-N 3.47Å; V168-V170 VanDerWaalsContact C-N 3.32Å; V168-V170 PolarHBondContact O-N 2.95Å; V170-L172 PolarHBondContact O-N 2.81Å; V170-L173 PolarHBondContact O-N 3.14Å; V170-L173 VanDerWaalsContact O-N 3.1Å; V170-Y174 HydrophobicContact CG1-CD2 3.58Å; V170-Y174 HydrophobicContact CG1-CE2 3.75Å; V170-Y174 WeakPolarHBondContact O-CB 2.96Å; V170-Y174 VanDerWaalsContact O-CD2 3.31Å; V170-Y174 WeakPolarHBondContact O-CD2 3.19Å; V170-Y174 PolarHBondContact O-N 3.15Å
171	D	84.7	Confident	75.6	Confident	30 Å²	30	96 Å²	96	16%	0.16	47%	0.473	C	S	.	.	H	α-helix	trans	-61.3	-34.1	176	-67.7	-14	0	0	0	111	S167 V168 R176	S167-D171 WeakPolarHBondContact O-CB 3.47Å; S167-D171 PolarHBondContact O-N 3Å; S167-D171 PolarHBondContact OG-OD2 3.49Å; V168-D171 PolarHBondContact O-N 2.89Å; D171-R176 HydrophobicContact CB-CB 4.27Å; D171-R176 HydrophobicContact CB-CG 4.47Å; D171-R176 PolarHBondContact O-N 3.39Å; D171-R176 WeakPolarHBondContact OD1-CD 3.2Å; D171-R176 IonicContact OD1-NE 3.28Å
172	L	83.8	Confident	77.6	Confident	39 Å²	39	88.4 Å²	88.4	20%	0.204	45%	0.447	C	S	.	.	H	α-helix	trans	-68.3	-43.1	172.5	-90.9	80.1	0	0	0	112.7	V168 V169 V170 W175 T181 V184	V168-L172 HydrophobicContact CG1-CD1 3.71Å; V168-L172 WeakPolarHBondContact O-CD1 3.38Å; V168-L172 PolarHBondContact O-N 2.93Å; V169-L172 WeakPolarHBondContact O-CB 3.33Å; V169-L172 PolarHBondContact O-N 2.88Å; V170-L172 PolarHBondContact O-N 2.81Å; L172-W175 PolarHBondContact O-N 3.4Å; L172-T181 VanDerWaalsContact CA-CG2 3.46Å; L172-T181 HydrophobicContact CB-CG2 4.32Å; L172-T181 HydrophobicContact CG-CG2 4.29Å; L172-T181 WeakPolarHBondContact O-CB 3.43Å; L172-T181 WeakPolarHBondContact O-CG2 3.33Å; L172-V184 HydrophobicContact CD2-CB 4.25Å; L172-V184 HydrophobicContact CD2-CG1 4.15Å; L172-V184 HydrophobicContact CD2-CG2 3.98Å
173	L	82.9	Confident	79.7	Confident	34 Å²	34	81.9 Å²	81.9	18%	0.178	43%	0.434	C	S	.	.	H	α-helix	trans	-71.7	-35.8	-176.8	-130.3	67.8	0	0	0	113	V169 V170 W175 L312 F313 P316	V169-L173 PolarHBondContact O-N 3.44Å; V170-L173 PolarHBondContact O-N 3.14Å; V170-L173 VanDerWaalsContact O-N 3.1Å; L173-W175 VanDerWaalsContact C-N 3.27Å; L173-W175 PolarHBondContact O-N 2.86Å; L173-L312 HydrophobicContact CD1-CD1 4.43Å; L173-L312 HydrophobicContact CD1-CD2 4.44Å; L173-L312 HydrophobicContact CD1-CG 3.89Å; L173-L312 HydrophobicContact CD2-CD1 4.11Å; L173-L312 HydrophobicContact CD2-CG 4.41Å; L173-L312 WeakPolarHBondContact CD2-O 3.35Å; L173-L312 VanDerWaalsContact CG-O 3.27Å; L173-L312 WeakPolarHBondContact CG-O 3.33Å; L173-F313 HydrophobicContact CD1-CD1 4.04Å; L173-F313 HydrophobicContact CD1-CD2 4.48Å; L173-F313 HydrophobicContact CD1-CE1 3.97Å; L173-F313 HydrophobicContact CD1-CE2 4.41Å; L173-F313 HydrophobicContact CD1-CG 4.31Å; L173-F313 HydrophobicContact CD1-CZ 4.16Å; L173-P316 HydrophobicContact CB-CG 4.46Å; L173-P316 HydrophobicContact CD2-CG 3.78Å; L173-P316 HydrophobicContact CG-CG 3.97Å
174	Y	79.8	Confident	81.6	Confident	91 Å²	91	76.8 Å²	76.8	36%	0.357	42%	0.421	S	S	.	.	T	Hydrogen-bonded Turn	trans	-86.4	11.6	178.1	-78.8	-97.6	0	0	0	113.4	V170 R176 P316	V170-Y174 HydrophobicContact CG1-CD2 3.58Å; V170-Y174 HydrophobicContact CG1-CE2 3.75Å; V170-Y174 WeakPolarHBondContact O-CB 2.96Å; V170-Y174 VanDerWaalsContact O-CD2 3.31Å; V170-Y174 WeakPolarHBondContact O-CD2 3.19Å; V170-Y174 PolarHBondContact O-N 3.15Å; Y174-R176 PolarHBondContact O-N 2.88Å; Y174-R176 VanDerWaalsContact O-N 3.08Å; Y174-P316 HydrophobicContact CD1-CB 4.38Å; Y174-P316 HydrophobicContact CD2-CB 4.28Å; Y174-P316 HydrophobicContact CE1-CB 4.21Å; Y174-P316 HydrophobicContact CE2-CB 4.11Å; Y174-P316 HydrophobicContact CG-CB 4.43Å
175	W	85.9	Confident	83.4	Confident	80 Å²	80	76.4 Å²	76.4	30%	0.303	41%	0.407	S	S	.	.	T	Hydrogen-bonded Turn	trans	55.7	26.8	179.9	-74	71.1	0	0	0	114.6	L172 L173 D177 I178 T181 F185 V317	L172-W175 PolarHBondContact O-N 3.4Å; L173-W175 VanDerWaalsContact C-N 3.27Å; L173-W175 PolarHBondContact O-N 2.86Å; W175-D177 PolarHBondContact O-N 3.01Å; W175-I178 HydrophobicContact CE3-CG1 4.3Å; W175-I178 HydrophobicContact CE3-CG2 4.31Å; W175-I178 HydrophobicContact CZ3-CG2 4.34Å; W175-I178 WeakPolarHBondContact O-CG1 3.49Å; W175-I178 PolarHBondContact O-N 2.83Å; W175-T181 VanDerWaalsContact CE3-OG1 3.25Å; W175-F185 HydrophobicContact CH2-CD1 4.3Å; W175-F185 HydrophobicContact CZ2-CD1 4.07Å; W175-F185 HydrophobicContact CZ2-CG 4.32Å; W175-V317 HydrophobicContact CB-CG2 4.35Å; W175-V317 HydrophobicContact CG-CG2 4.06Å
176	R	85.5	Confident	85	Confident	170 Å²	170	73.2 Å²	73.2	64%	0.642	39%	0.391	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.1	-34.4	-175.9	-61.7	-173.8	77.9	92.4	2.7	112	D171 Y174	D171-R176 HydrophobicContact CB-CB 4.27Å; D171-R176 HydrophobicContact CB-CG 4.47Å; D171-R176 PolarHBondContact O-N 3.39Å; D171-R176 WeakPolarHBondContact OD1-CD 3.2Å; D171-R176 IonicContact OD1-NE 3.28Å; Y174-R176 PolarHBondContact O-N 2.88Å; Y174-R176 VanDerWaalsContact O-N 3.08Å
177	D	84.9	Confident	86.3	Confident	72 Å²	72	73.8 Å²	73.8	39%	0.385	39%	0.391	S	S	.	.	T	Hydrogen-bonded Turn	trans	-111.3	73.6	173.4	-79.4	-21.6	0	0	0	110.6	W175 K179 K180 T181	W175-D177 PolarHBondContact O-N 3.01Å; D177-K179 CarbonylContact O-C 3.24Å; D177-K179 PolarHBondContact O-N 2.99Å; D177-K180 HydrophobicContact CB-CB 4.06Å; D177-K180 HydrophobicContact CB-CD 4.16Å; D177-K180 HydrophobicContact CB-CG 4.21Å; D177-K180 PolarHBondContact O-N 3.15Å; D177-K180 IonicContact OD2-NZ 3.85Å; D177-K180 PolarHBondContact OD2-NZ 2.79Å; D177-T181 HydrophobicContact CB-CG2 4.44Å; D177-T181 VanDerWaalsContact O-CG2 3.28Å; D177-T181 WeakPolarHBondContact O-CG2 3.2Å; D177-T181 PolarHBondContact O-N 3.2Å; D177-T181 PolarHBondContact O-OG1 2.83Å
178	I	84.9	Confident	87	Confident	120 Å²	120	73.1 Å²	73.1	62%	0.615	39%	0.386	S	S	*	.	H	α-helix	trans	-42.6	-38	-175.3	-66.9	152.6	0	0	0	113.9	W175 T181 G182	W175-I178 HydrophobicContact CE3-CG1 4.3Å; W175-I178 HydrophobicContact CE3-CG2 4.31Å; W175-I178 HydrophobicContact CZ3-CG2 4.34Å; W175-I178 WeakPolarHBondContact O-CG1 3.49Å; W175-I178 PolarHBondContact O-N 2.83Å; I178-T181 WeakPolarHBondContact CA-OG1 3.14Å; I178-T181 PolarHBondContact O-OG1 2.79Å; I178-G182 WeakPolarHBondContact O-CA 3.45Å; I178-G182 PolarHBondContact O-N 3.34Å
179	K	88.6	Confident	87.7	Confident	184 Å²	184	71.7 Å²	71.7	80%	0.8	38%	0.376	S	S	*	.	H	α-helix	trans	-65.1	-46.1	177.6	-61.1	-178.5	-176.4	-179	0	112.4	D177 V183	D177-K179 CarbonylContact O-C 3.24Å; D177-K179 PolarHBondContact O-N 2.99Å; K179-V183 WeakPolarHBondContact O-CB 3.39Å; K179-V183 WeakPolarHBondContact O-CG2 3.13Å; K179-V183 PolarHBondContact O-N 2.93Å
180	K	88.2	Confident	88.3	Confident	124 Å²	124	74.5 Å²	74.5	54%	0.539	38%	0.381	S	S	.	.	H	α-helix	trans	-75.9	-45.4	180	-61.4	-178.2	-166.8	141.6	0	110.7	D177 V183 V184	D177-K180 HydrophobicContact CB-CB 4.06Å; D177-K180 HydrophobicContact CB-CD 4.16Å; D177-K180 HydrophobicContact CB-CG 4.21Å; D177-K180 PolarHBondContact O-N 3.15Å; D177-K180 IonicContact OD2-NZ 3.85Å; D177-K180 PolarHBondContact OD2-NZ 2.79Å; K180-V183 PolarHBondContact O-N 3.43Å; K180-V184 VanDerWaalsContact O-CG2 3.29Å; K180-V184 WeakPolarHBondContact O-CG2 3.36Å; K180-V184 PolarHBondContact O-N 3.47Å
181	T	89.3	Confident	88.7	Confident	0 Å²	0	74.9 Å²	74.9	0%	0	38%	0.38	C	S	.	.	H	α-helix	trans	-65.4	-42.1	-178.9	69.2	0	0	0	0	110.6	L172 W175 D177 I178 V184 F185	L172-T181 VanDerWaalsContact CA-CG2 3.46Å; L172-T181 HydrophobicContact CB-CG2 4.32Å; L172-T181 HydrophobicContact CG-CG2 4.29Å; L172-T181 WeakPolarHBondContact O-CB 3.43Å; L172-T181 WeakPolarHBondContact O-CG2 3.33Å; W175-T181 VanDerWaalsContact CE3-OG1 3.25Å; D177-T181 HydrophobicContact CB-CG2 4.44Å; D177-T181 VanDerWaalsContact O-CG2 3.28Å; D177-T181 WeakPolarHBondContact O-CG2 3.2Å; D177-T181 PolarHBondContact O-N 3.2Å; D177-T181 PolarHBondContact O-OG1 2.83Å; I178-T181 WeakPolarHBondContact CA-OG1 3.14Å; I178-T181 PolarHBondContact O-OG1 2.79Å; T181-V184 PolarHBondContact O-N 2.87Å; T181-F185 WeakPolarHBondContact O-CB 3.39Å; T181-F185 PolarHBondContact O-N 3.45Å
182	G	91.4	Very high	89	Confident	25 Å²	25	74.5 Å²	74.5	26%	0.258	38%	0.378	S	S	.	.	H	α-helix	trans	-65.1	-39.5	175.9	0	0	0	0	0	113.1	I178 G186	I178-G182 WeakPolarHBondContact O-CA 3.45Å; I178-G182 PolarHBondContact O-N 3.34Å; G182-G186 WeakPolarHBondContact O-CA 3.04Å; G182-G186 PolarHBondContact O-N 2.88Å
183	V	92.7	Very high	89.3	Confident	103 Å²	103	77.1 Å²	77.1	62%	0.624	39%	0.392	S	S	*	.	H	α-helix	trans	-67	-44.6	174.1	169.8	0	0	0	0	111.1	K179 K180 A187	K179-V183 WeakPolarHBondContact O-CB 3.39Å; K179-V183 WeakPolarHBondContact O-CG2 3.13Å; K179-V183 PolarHBondContact O-N 2.93Å; K180-V183 PolarHBondContact O-N 3.43Å; V183-A187 WeakPolarHBondContact O-CB 3.32Å; V183-A187 PolarHBondContact O-N 3.37Å
184	V	91.5	Very high	89.6	Confident	65 Å²	65	76.6 Å²	76.6	39%	0.394	39%	0.39	S	S	.	.	H	α-helix	trans	-66.9	-46.6	179.3	173.9	0	0	0	0	111.1	L172 K180 T181 S188 F313	L172-V184 HydrophobicContact CD2-CB 4.25Å; L172-V184 HydrophobicContact CD2-CG1 4.15Å; L172-V184 HydrophobicContact CD2-CG2 3.98Å; K180-V184 VanDerWaalsContact O-CG2 3.29Å; K180-V184 WeakPolarHBondContact O-CG2 3.36Å; K180-V184 PolarHBondContact O-N 3.47Å; T181-V184 PolarHBondContact O-N 2.87Å; V184-S188 VanDerWaalsContact O-CB 3.27Å; V184-S188 WeakPolarHBondContact O-CB 3.38Å; V184-S188 PolarHBondContact O-N 2.81Å; V184-S188 PolarHBondContact O-OG 3.47Å; V184-F313 HydrophobicContact CG1-CZ 4.43Å
185	F	93	Very high	90	Very high	35 Å²	35	73.3 Å²	73.3	15%	0.154	38%	0.379	C	S	.	.	H	α-helix	trans	-62.4	-46	175.8	176.9	-108.1	0	0	0	111.3	W175 T181 S188 L189 I310 F313	W175-F185 HydrophobicContact CH2-CD1 4.3Å; W175-F185 HydrophobicContact CZ2-CD1 4.07Å; W175-F185 HydrophobicContact CZ2-CG 4.32Å; T181-F185 WeakPolarHBondContact O-CB 3.39Å; T181-F185 PolarHBondContact O-N 3.45Å; F185-S188 WeakPolarHBondContact CA-OG 3.18Å; F185-S188 PolarHBondContact O-OG 2.93Å; F185-L189 HydrophobicContact CE1-CD2 4.08Å; F185-L189 HydrophobicContact CZ-CD2 4.06Å; F185-L189 WeakPolarHBondContact O-CB 3.49Å; F185-L189 PolarHBondContact O-N 3.41Å; F185-I310 HydrophobicContact CE2-CG1 4.23Å; F185-I310 HydrophobicContact CZ-CG1 4.1Å; F185-F313 HydrophobicContact CD2-CB 3.98Å; F185-F313 AromaticContact CD2-CD2 3.72Å; F185-F313 HydrophobicContact CD2-CD2 3.72Å; F185-F313 HydrophobicContact CD2-CE2 4.35Å; F185-F313 AromaticContact CD2-CG 3.84Å; F185-F313 HydrophobicContact CD2-CG 3.84Å; F185-F313 HydrophobicContact CE2-CB 4.27Å; F185-F313 HydrophobicContact CE2-CD2 4.4Å
186	G	93.9	Very high	90	Very high	34 Å²	34	71.7 Å²	71.7	35%	0.351	38%	0.378	S	S	.	.	H	α-helix	trans	-64.4	-44.8	178.2	0	0	0	0	0	112.8	G182 L189 F190	G182-G186 WeakPolarHBondContact O-CA 3.04Å; G182-G186 PolarHBondContact O-N 2.88Å; G186-L189 PolarHBondContact O-N 3.25Å; G186-F190 WeakPolarHBondContact O-CB 3.2Å; G186-F190 PolarHBondContact O-N 2.78Å
187	A	93.3	Very high	90	Very high	57 Å²	57	68.8 Å²	68.8	47%	0.471	38%	0.379	S	S	.	.	H	α-helix	trans	-66.9	-42.5	177.4	0	0	0	0	0	112	V183 L191	V183-A187 WeakPolarHBondContact O-CB 3.32Å; V183-A187 PolarHBondContact O-N 3.37Å; A187-L191 VanDerWaalsContact O-CB 3.25Å; A187-L191 WeakPolarHBondContact O-CB 3.36Å; A187-L191 PolarHBondContact O-N 2.75Å
188	S	92.7	Very high	90	Very high	29 Å²	29	71 Å²	71	20%	0.203	39%	0.385	C	S	.	.	H	α-helix	trans	-67	-40.8	175.9	52.9	0	0	0	0	112	V184 F185 L191 L192 L309	V184-S188 VanDerWaalsContact O-CB 3.27Å; V184-S188 WeakPolarHBondContact O-CB 3.38Å; V184-S188 PolarHBondContact O-N 2.81Å; V184-S188 PolarHBondContact O-OG 3.47Å; F185-S188 WeakPolarHBondContact CA-OG 3.18Å; F185-S188 PolarHBondContact O-OG 2.93Å; S188-L191 PolarHBondContact O-N 3.24Å; S188-L192 WeakPolarHBondContact O-CG 3.49Å; S188-L192 PolarHBondContact O-N 3Å; S188-L309 WeakPolarHBondContact OG-CD2 3.21Å
189	L	93	Very high	90	Very high	49 Å²	49	68.7 Å²	68.7	26%	0.257	38%	0.38	S	S	.	.	H	α-helix	trans	-66.4	-43.8	175	-175.8	64.3	0	0	0	111.7	F185 G186 L191 L192 L193 I306 L309 I310	F185-L189 HydrophobicContact CE1-CD2 4.08Å; F185-L189 HydrophobicContact CZ-CD2 4.06Å; F185-L189 WeakPolarHBondContact O-CB 3.49Å; F185-L189 PolarHBondContact O-N 3.41Å; G186-L189 PolarHBondContact O-N 3.25Å; L189-L191 VanDerWaalsContact C-N 3.34Å; L189-L192 PolarHBondContact O-N 3.04Å; L189-L193 VanDerWaalsContact O-CB 3.27Å; L189-L193 WeakPolarHBondContact O-CB 3.5Å; L189-L193 PolarHBondContact O-N 3.29Å; L189-I306 HydrophobicContact CD1-CG2 3.76Å; L189-L309 HydrophobicContact CB-CD2 4.31Å; L189-I310 HydrophobicContact CD1-CD1 4.36Å; L189-I310 HydrophobicContact CD1-CG1 4.32Å
190	F	92.3	Very high	89.8	Confident	152 Å²	152	64.5 Å²	64.5	67%	0.667	37%	0.365	S	S	*	.	H	α-helix	trans	-61.3	-43.4	175.6	177.1	-99.9	0	0	0	111.2	G186 L193 S194	G186-F190 WeakPolarHBondContact O-CB 3.2Å; G186-F190 PolarHBondContact O-N 2.78Å; F190-L193 PolarHBondContact O-N 3.37Å; F190-S194 WeakPolarHBondContact O-CB 3.33Å; F190-S194 PolarHBondContact O-N 3.23Å; F190-S194 PolarHBondContact O-OG 2.7Å
191	L	90.7	Very high	89.7	Confident	80 Å²	80	64 Å²	64	42%	0.419	37%	0.372	S	S	.	.	H	α-helix	trans	-60.4	-52.4	175	-178.5	62.5	0	0	0	110.2	A187 S188 L189 L193 S194 L195 V203	A187-L191 VanDerWaalsContact O-CB 3.25Å; A187-L191 WeakPolarHBondContact O-CB 3.36Å; A187-L191 PolarHBondContact O-N 2.75Å; S188-L191 PolarHBondContact O-N 3.24Å; L189-L191 VanDerWaalsContact C-N 3.34Å; L191-L193 VanDerWaalsContact C-N 3.28Å; L191-L193 PolarHBondContact O-N 2.78Å; L191-S194 PolarHBondContact O-N 3.18Å; L191-S194 VanDerWaalsContact O-N 3.14Å; L191-S194 PolarHBondContact O-OG 2.98Å; L191-L195 HydrophobicContact CD1-CD1 3.66Å; L191-L195 HydrophobicContact CG-CD1 3.83Å; L191-L195 WeakPolarHBondContact O-CD1 3.49Å; L191-L195 PolarHBondContact O-N 3.15Å; L191-V203 HydrophobicContact CD1-CG1 3.92Å
192	L	91.1	Very high	89.7	Confident	22 Å²	22	65.6 Å²	65.6	12%	0.115	38%	0.384	C	S	.	.	H	α-helix	trans	-59.5	-38.1	177.4	-70.8	-178.3	0	0	0	113	S188 L189 L195 T196 L305 I306 L309	S188-L192 WeakPolarHBondContact O-CG 3.49Å; S188-L192 PolarHBondContact O-N 3Å; L189-L192 PolarHBondContact O-N 3.04Å; L192-L195 WeakPolarHBondContact O-CB 3.29Å; L192-L195 PolarHBondContact O-N 3.49Å; L192-T196 WeakPolarHBondContact O-CG2 3.28Å; L192-T196 PolarHBondContact O-N 3.37Å; L192-T196 VanDerWaalsContact O-N 3.09Å; L192-L305 HydrophobicContact CD1-CG 4.08Å; L192-L305 HydrophobicContact CD2-CD2 3.39Å; L192-L305 HydrophobicContact CD2-CG 3.7Å; L192-I306 HydrophobicContact CB-CD1 4.31Å; L192-I306 HydrophobicContact CB-CG1 3.66Å; L192-I306 HydrophobicContact CD1-CG1 4.05Å; L192-I306 HydrophobicContact CG-CG1 4.48Å; L192-L309 HydrophobicContact CD1-CB 3.86Å; L192-L309 HydrophobicContact CD1-CD2 3.51Å; L192-L309 HydrophobicContact CD1-CG 4.26Å; L192-L309 HydrophobicContact CG-CD2 4.43Å
193	L	90	Very high	89.5	Confident	94 Å²	94	65.2 Å²	65.2	49%	0.492	38%	0.376	S	S	.	.	H	α-helix	trans	-67.8	-41.6	176.3	-171.4	66.3	0	0	0	111.2	L189 F190 L191 L195 T196 V197	L189-L193 VanDerWaalsContact O-CB 3.27Å; L189-L193 WeakPolarHBondContact O-CB 3.5Å; L189-L193 PolarHBondContact O-N 3.29Å; F190-L193 PolarHBondContact O-N 3.37Å; L191-L193 VanDerWaalsContact C-N 3.28Å; L191-L193 PolarHBondContact O-N 2.78Å; L193-L195 PolarHBondContact O-N 3.08Å; L193-T196 WeakPolarHBondContact O-CB 3.32Å; L193-T196 PolarHBondContact O-N 3.38Å; L193-T196 PolarHBondContact O-OG1 2.88Å; L193-V197 PolarHBondContact O-N 2.93Å
194	S	89.8	Confident	89.2	Confident	22 Å²	22	64.4 Å²	64.4	15%	0.154	37%	0.372	C	S	.	.	H	α-helix	trans	-60.4	-38	172.3	71	0	0	0	0	111	F190 L191 T196 V197 F198	F190-S194 WeakPolarHBondContact O-CB 3.33Å; F190-S194 PolarHBondContact O-N 3.23Å; F190-S194 PolarHBondContact O-OG 2.7Å; L191-S194 PolarHBondContact O-N 3.18Å; L191-S194 VanDerWaalsContact O-N 3.14Å; L191-S194 PolarHBondContact O-OG 2.98Å; S194-T196 PolarHBondContact O-N 2.86Å; S194-V197 PolarHBondContact O-N 3.24Å; S194-F198 WeakPolarHBondContact O-CA 3.28Å; S194-F198 VanDerWaalsContact O-CB 3.3Å; S194-F198 WeakPolarHBondContact O-CB 3.19Å; S194-F198 PolarHBondContact O-N 2.82Å
195	L	88.2	Confident	89.2	Confident	23 Å²	23	63.4 Å²	63.4	12%	0.12	37%	0.37	C	S	.	.	H	α-helix	trans	-65.9	-24.4	174.1	-88.9	78.4	0	0	0	112.8	L191 L192 L193 F198 I200 V203 L302	L191-L195 HydrophobicContact CD1-CD1 3.66Å; L191-L195 HydrophobicContact CG-CD1 3.83Å; L191-L195 WeakPolarHBondContact O-CD1 3.49Å; L191-L195 PolarHBondContact O-N 3.15Å; L192-L195 WeakPolarHBondContact O-CB 3.29Å; L192-L195 PolarHBondContact O-N 3.49Å; L193-L195 PolarHBondContact O-N 3.08Å; L195-F198 CarbonylContact C-O 3.51Å; L195-F198 VanDerWaalsContact C-O 3.24Å; L195-F198 VanDerWaalsContact CA-O 3.31Å; L195-F198 WeakPolarHBondContact CA-O 3.41Å; L195-I200 HydrophobicContact CD2-CB 4.28Å; L195-I200 HydrophobicContact CD2-CD1 3.61Å; L195-I200 HydrophobicContact CD2-CG1 3.51Å; L195-I200 HydrophobicContact CD2-CG2 4.15Å; L195-I200 HydrophobicContact CG-CB 4.46Å; L195-I200 HydrophobicContact CG-CD1 4.48Å; L195-I200 HydrophobicContact CG-CG1 3.85Å; L195-V203 HydrophobicContact CD1-CG1 4.27Å; L195-V203 HydrophobicContact CD1-CG2 4.43Å; L195-L302 HydrophobicContact CB-CD1 4.5Å; L195-L302 HydrophobicContact CB-CD2 3.96Å; L195-L302 HydrophobicContact CD2-CD2 4.27Å; L195-L302 WeakPolarHBondContact O-CD1 3.17Å
196	T	85.9	Confident	89.2	Confident	45 Å²	45	69 Å²	69	28%	0.276	39%	0.391	S	S	.	.	H	α-helix	trans	-77	-27	176.6	69.7	0	0	0	0	113.4	L192 L193 S194 L302 I306	L192-T196 WeakPolarHBondContact O-CG2 3.28Å; L192-T196 PolarHBondContact O-N 3.37Å; L192-T196 VanDerWaalsContact O-N 3.09Å; L193-T196 WeakPolarHBondContact O-CB 3.32Å; L193-T196 PolarHBondContact O-N 3.38Å; L193-T196 PolarHBondContact O-OG1 2.88Å; S194-T196 PolarHBondContact O-N 2.86Å; T196-L302 HydrophobicContact CG2-CB 3.76Å; T196-L302 HydrophobicContact CG2-CD1 4.27Å; T196-I306 HydrophobicContact CG2-CD1 3.46Å; T196-I306 VanDerWaalsContact CG2-CD1 3.46Å
197	V	84.3	Confident	89.1	Confident	110 Å²	110	71.7 Å²	71.7	67%	0.667	40%	0.397	S	S	*	.	H	α-helix	trans	-101	-32.5	-178.6	-177.6	0	0	0	0	111.2	L193 S194	L193-V197 PolarHBondContact O-N 2.93Å; S194-V197 PolarHBondContact O-N 3.24Å
198	F	85.7	Confident	89.1	Confident	117 Å²	117	71.4 Å²	71.4	51%	0.513	39%	0.394	S	S	.	.	S	Bend	trans	-118.4	148.8	-179.8	-66.4	-91.3	0	0	0	111.1	S194 L195 V203	S194-F198 WeakPolarHBondContact O-CA 3.28Å; S194-F198 VanDerWaalsContact O-CB 3.3Å; S194-F198 WeakPolarHBondContact O-CB 3.19Å; S194-F198 PolarHBondContact O-N 2.82Å; L195-F198 CarbonylContact C-O 3.51Å; L195-F198 VanDerWaalsContact C-O 3.24Å; L195-F198 VanDerWaalsContact CA-O 3.31Å; L195-F198 WeakPolarHBondContact CA-O 3.41Å; F198-V203 HydrophobicContact CB-CG2 3.83Å
199	S	85.4	Confident	89.1	Confident	73 Å²	73	75 Å²	75	51%	0.51	41%	0.411	S	S	.	.			trans	-60.9	141.2	173.6	178.4	0	0	0	0	111.9	V201 S202 V203	S199-V201 PolarHBondContact O-N 2.9Å; S199-V201 VanDerWaalsContact O-N 3.14Å; S199-V201 PolarHBondContact OG-N 2.79Å; S199-S202 PolarHBondContact N-OG 3.36Å; S199-S202 PolarHBondContact O-N 2.79Å; S199-S202 PolarHBondContact O-OG 2.85Å; S199-V203 WeakPolarHBondContact O-CG2 3.4Å; S199-V203 PolarHBondContact O-N 3.39Å
200	I	84.3	Confident	89.2	Confident	95 Å²	95	75 Å²	75	49%	0.487	42%	0.418	S	S	.	.	H	α-helix	trans	-53.8	-36.8	174.6	-49.6	-169.4	0	0	0	111.1	L195 T204	L195-I200 HydrophobicContact CD2-CB 4.28Å; L195-I200 HydrophobicContact CD2-CD1 3.61Å; L195-I200 HydrophobicContact CD2-CG1 3.51Å; L195-I200 HydrophobicContact CD2-CG2 4.15Å; L195-I200 HydrophobicContact CG-CB 4.46Å; L195-I200 HydrophobicContact CG-CD1 4.48Å; L195-I200 HydrophobicContact CG-CG1 3.85Å; I200-T204 WeakPolarHBondContact O-CB 3.39Å; I200-T204 PolarHBondContact O-N 2.8Å; I200-T204 PolarHBondContact O-OG1 3.36Å
201	V	85.7	Confident	89.2	Confident	113 Å²	113	73 Å²	73	69%	0.685	41%	0.414	S	S	*	.	H	α-helix	trans	-64.8	-45.8	179.2	-179.6	0	0	0	0	110.5	S199 T204 A205	S199-V201 PolarHBondContact O-N 2.9Å; S199-V201 VanDerWaalsContact O-N 3.14Å; S199-V201 PolarHBondContact OG-N 2.79Å; V201-T204 PolarHBondContact O-N 2.8Å; V201-A205 WeakPolarHBondContact O-CB 3.14Å; V201-A205 PolarHBondContact O-N 2.89Å
202	S	89.5	Confident	89.3	Confident	34 Å²	34	73.9 Å²	73.9	24%	0.238	42%	0.418	C	S	.	.	H	α-helix	trans	-69.6	-41.5	179.4	60.9	0	0	0	0	111.8	S199 T204 A205 Y206	S199-S202 PolarHBondContact N-OG 3.36Å; S199-S202 PolarHBondContact O-N 2.79Å; S199-S202 PolarHBondContact O-OG 2.85Å; S202-T204 VanDerWaalsContact C-N 3.28Å; S202-T204 PolarHBondContact O-N 3.31Å; S202-A205 PolarHBondContact O-N 3.35Å; S202-Y206 WeakPolarHBondContact O-CD2 3.12Å; S202-Y206 PolarHBondContact O-N 2.79Å
203	V	86.9	Confident	89.5	Confident	18 Å²	18	75.8 Å²	75.8	11%	0.109	43%	0.433	C	S	.	.	H	α-helix	trans	-56.6	-45.3	174.1	175.9	0	0	0	0	110.8	L191 L195 F198 S199 Y206 I207	L191-V203 HydrophobicContact CD1-CG1 3.92Å; L195-V203 HydrophobicContact CD1-CG1 4.27Å; L195-V203 HydrophobicContact CD1-CG2 4.43Å; F198-V203 HydrophobicContact CB-CG2 3.83Å; S199-V203 WeakPolarHBondContact O-CG2 3.4Å; S199-V203 PolarHBondContact O-N 3.39Å; V203-Y206 PolarHBondContact O-N 3.49Å; V203-I207 HydrophobicContact CG1-CD1 4.02Å; V203-I207 VanDerWaalsContact O-CG1 3.3Å; V203-I207 WeakPolarHBondContact O-CG1 3.25Å; V203-I207 PolarHBondContact O-N 2.82Å; V203-I207 VanDerWaalsContact O-N 3.09Å
204	T	86.1	Confident	89.7	Confident	86 Å²	86	75.9 Å²	75.9	53%	0.528	44%	0.438	S	S	.	.	H	α-helix	trans	-65.6	-43.5	178.2	-54.6	0	0	0	0	111.5	I200 V201 S202 I207 A208	I200-T204 WeakPolarHBondContact O-CB 3.39Å; I200-T204 PolarHBondContact O-N 2.8Å; I200-T204 PolarHBondContact O-OG1 3.36Å; V201-T204 PolarHBondContact O-N 2.8Å; S202-T204 VanDerWaalsContact C-N 3.28Å; S202-T204 PolarHBondContact O-N 3.31Å; T204-I207 PolarHBondContact O-N 2.88Å; T204-A208 WeakPolarHBondContact O-CB 3.45Å; T204-A208 PolarHBondContact O-N 3.09Å
205	A	92.5	Very high	89.7	Confident	44 Å²	44	77.3 Å²	77.3	36%	0.364	45%	0.445	S	S	.	.	H	α-helix	trans	-61.1	-46.3	177.5	0	0	0	0	0	111.6	V201 S202 I207 A208 L209	V201-A205 WeakPolarHBondContact O-CB 3.14Å; V201-A205 PolarHBondContact O-N 2.89Å; S202-A205 PolarHBondContact O-N 3.35Å; A205-I207 PolarHBondContact O-N 3.46Å; A205-A208 PolarHBondContact O-N 3.45Å; A205-L209 WeakPolarHBondContact O-CB 3.17Å; A205-L209 VanDerWaalsContact O-CG 3.26Å; A205-L209 WeakPolarHBondContact O-CG 3.11Å; A205-L209 PolarHBondContact O-N 2.82Å
206	Y	91.9	Very high	89.9	Confident	152 Å²	152	80.3 Å²	80.3	60%	0.596	46%	0.461	S	S	*	.	H	α-helix	trans	-63.9	-39.5	177.9	-73.3	-56.7	0	0	0	112.8	S202 V203 L209 A210	S202-Y206 WeakPolarHBondContact O-CD2 3.12Å; S202-Y206 PolarHBondContact O-N 2.79Å; V203-Y206 PolarHBondContact O-N 3.49Å; Y206-L209 PolarHBondContact O-N 3.45Å; Y206-A210 WeakPolarHBondContact O-CB 3.25Å; Y206-A210 PolarHBondContact O-N 2.77Å
207	I	91.5	Very high	90.2	Very high	90 Å²	90	81.8 Å²	81.8	46%	0.462	47%	0.473	S	S	.	.	H	α-helix	trans	-63.3	-45.4	173.8	-67.5	167.3	0	0	0	110.1	V203 T204 A205 A210 L211	V203-I207 HydrophobicContact CG1-CD1 4.02Å; V203-I207 VanDerWaalsContact O-CG1 3.3Å; V203-I207 WeakPolarHBondContact O-CG1 3.25Å; V203-I207 PolarHBondContact O-N 2.82Å; V203-I207 VanDerWaalsContact O-N 3.09Å; T204-I207 PolarHBondContact O-N 2.88Å; A205-I207 PolarHBondContact O-N 3.46Å; I207-A210 PolarHBondContact O-N 3.38Å; I207-L211 HydrophobicContact CG2-CD1 4Å; I207-L211 HydrophobicContact CG2-CG 4.41Å; I207-L211 WeakPolarHBondContact O-CB 3.3Å; I207-L211 VanDerWaalsContact O-CG 3.25Å; I207-L211 WeakPolarHBondContact O-CG 3.26Å; I207-L211 PolarHBondContact O-N 3.2Å
208	A	92.8	Very high	90.5	Very high	51 Å²	51	80.1 Å²	80.1	42%	0.421	46%	0.457	S	S	.	.	H	α-helix	trans	-62.8	-43.2	178.1	0	0	0	0	0	111.9	T204 A205 L211 L212	T204-A208 WeakPolarHBondContact O-CB 3.45Å; T204-A208 PolarHBondContact O-N 3.09Å; A205-A208 PolarHBondContact O-N 3.45Å; A208-L211 PolarHBondContact O-N 2.92Å; A208-L212 WeakPolarHBondContact O-CB 3.38Å; A208-L212 PolarHBondContact O-N 3.5Å
209	L	94.6	Very high	90.5	Very high	105 Å²	105	77.2 Å²	77.2	55%	0.55	44%	0.442	S	S	.	.	H	α-helix	trans	-64.6	-41.8	175.8	-73.4	174.1	0	0	0	111.7	A205 Y206 L212 S213	A205-L209 WeakPolarHBondContact O-CB 3.17Å; A205-L209 VanDerWaalsContact O-CG 3.26Å; A205-L209 WeakPolarHBondContact O-CG 3.11Å; A205-L209 PolarHBondContact O-N 2.82Å; Y206-L209 PolarHBondContact O-N 3.45Å; L209-L212 PolarHBondContact O-N 2.85Å; L209-S213 WeakPolarHBondContact O-CB 3.27Å; L209-S213 PolarHBondContact O-N 2.78Å; L209-S213 PolarHBondContact O-OG 3.32Å
210	A	94.8	Very high	90.7	Very high	49 Å²	49	78.8 Å²	78.8	41%	0.405	44%	0.444	S	S	.	.	H	α-helix	trans	-64.6	-40.4	175.3	0	0	0	0	0	111.8	Y206 I207 S213 V214	Y206-A210 WeakPolarHBondContact O-CB 3.25Å; Y206-A210 PolarHBondContact O-N 2.77Å; I207-A210 PolarHBondContact O-N 3.38Å; A210-S213 WeakPolarHBondContact CA-OG 3.44Å; A210-S213 PolarHBondContact O-OG 3.43Å; A210-V214 WeakPolarHBondContact O-CB 3.04Å; A210-V214 WeakPolarHBondContact O-CG2 3.45Å; A210-V214 PolarHBondContact O-N 3.17Å
211	L	92.6	Very high	91	Very high	111 Å²	111	81.3 Å²	81.3	58%	0.581	45%	0.448	S	S	*	.	H	α-helix	trans	-68.3	-39.4	174.3	-68.9	174.1	0	0	0	111.4	I207 A208 T215	I207-L211 HydrophobicContact CG2-CD1 4Å; I207-L211 HydrophobicContact CG2-CG 4.41Å; I207-L211 WeakPolarHBondContact O-CB 3.3Å; I207-L211 VanDerWaalsContact O-CG 3.25Å; I207-L211 WeakPolarHBondContact O-CG 3.26Å; I207-L211 PolarHBondContact O-N 3.2Å; A208-L211 PolarHBondContact O-N 2.92Å; L211-T215 WeakPolarHBondContact O-CB 3.26Å; L211-T215 WeakPolarHBondContact O-CG2 3.27Å; L211-T215 PolarHBondContact O-N 3.28Å; L211-T215 PolarHBondContact O-OG1 2.88Å
212	L	92.1	Very high	90.9	Very high	98 Å²	98	79.1 Å²	79.1	51%	0.513	43%	0.43	S	S	.	.	H	α-helix	trans	-63.8	-46.5	174.8	-101.5	-177.9	0	0	0	111.5	A208 L209 V214 T215 I216	A208-L212 WeakPolarHBondContact O-CB 3.38Å; A208-L212 PolarHBondContact O-N 3.5Å; L209-L212 PolarHBondContact O-N 2.85Å; L212-V214 PolarHBondContact O-N 3.44Å; L212-T215 VanDerWaalsContact CA-OG1 3.32Å; L212-T215 WeakPolarHBondContact CA-OG1 3.06Å; L212-T215 PolarHBondContact O-N 3.11Å; L212-T215 PolarHBondContact O-OG1 2.92Å; L212-I216 HydrophobicContact CD2-CD1 4.26Å; L212-I216 HydrophobicContact CD2-CG1 4.49Å; L212-I216 WeakPolarHBondContact O-CB 3.17Å; L212-I216 WeakPolarHBondContact O-CD1 3.35Å; L212-I216 WeakPolarHBondContact O-CG1 3.49Å; L212-I216 PolarHBondContact O-N 2.72Å
213	S	96	Very high	90.7	Very high	61 Å²	61	79 Å²	79	43%	0.427	43%	0.434	S	S	.	.	H	α-helix	trans	-61.3	-46.7	178.3	69.2	0	0	0	0	110.8	L209 A210 T215 I216 S217	L209-S213 WeakPolarHBondContact O-CB 3.27Å; L209-S213 PolarHBondContact O-N 2.78Å; L209-S213 PolarHBondContact O-OG 3.32Å; A210-S213 WeakPolarHBondContact CA-OG 3.44Å; A210-S213 PolarHBondContact O-OG 3.43Å; S213-T215 PolarHBondContact O-N 3.31Å; S213-I216 PolarHBondContact O-N 3.04Å; S213-S217 WeakPolarHBondContact O-CB 2.98Å; S213-S217 PolarHBondContact O-N 2.77Å; S213-S217 PolarHBondContact O-OG 3.21Å
214	V	92.9	Very high	90.8	Very high	97 Å²	97	81.9 Å²	81.9	59%	0.588	45%	0.451	S	S	*	.	H	α-helix	trans	-59.9	-43.9	175.5	170.7	0	0	0	0	111.7	A210 L212 F218	A210-V214 WeakPolarHBondContact O-CB 3.04Å; A210-V214 WeakPolarHBondContact O-CG2 3.45Å; A210-V214 PolarHBondContact O-N 3.17Å; L212-V214 PolarHBondContact O-N 3.44Å; V214-F218 WeakPolarHBondContact O-CB 3.46Å; V214-F218 PolarHBondContact O-N 2.9Å
215	T	90.6	Very high	90.8	Very high	51 Å²	51	80 Å²	80	31%	0.313	44%	0.438	S	S	.	.	H	α-helix	trans	-69.2	-40.8	179.8	52.8	0	0	0	0	112.4	L211 L212 S213 F218 R219 F237	L211-T215 WeakPolarHBondContact O-CB 3.26Å; L211-T215 WeakPolarHBondContact O-CG2 3.27Å; L211-T215 PolarHBondContact O-N 3.28Å; L211-T215 PolarHBondContact O-OG1 2.88Å; L212-T215 VanDerWaalsContact CA-OG1 3.32Å; L212-T215 WeakPolarHBondContact CA-OG1 3.06Å; L212-T215 PolarHBondContact O-N 3.11Å; L212-T215 PolarHBondContact O-OG1 2.92Å; S213-T215 PolarHBondContact O-N 3.31Å; T215-F218 PolarHBondContact O-N 3.1Å; T215-R219 WeakPolarHBondContact O-CB 3.31Å; T215-R219 WeakPolarHBondContact O-CG 3.47Å; T215-R219 PolarHBondContact O-N 3.25Å; T215-F237 HydrophobicContact CG2-CE2 3.94Å; T215-F237 HydrophobicContact CG2-CZ 4.1Å
216	I	91.3	Very high	90.4	Very high	87 Å²	87	80.9 Å²	80.9	45%	0.446	43%	0.434	S	S	.	.	H	α-helix	trans	-64.6	-49.5	175.6	-68.2	164.8	0	0	0	110.3	L212 S213 F218 R219 I220	L212-I216 HydrophobicContact CD2-CD1 4.26Å; L212-I216 HydrophobicContact CD2-CG1 4.49Å; L212-I216 WeakPolarHBondContact O-CB 3.17Å; L212-I216 WeakPolarHBondContact O-CD1 3.35Å; L212-I216 WeakPolarHBondContact O-CG1 3.49Å; L212-I216 PolarHBondContact O-N 2.72Å; S213-I216 PolarHBondContact O-N 3.04Å; I216-F218 VanDerWaalsContact C-N 3.32Å; I216-F218 PolarHBondContact O-N 3.3Å; I216-R219 WeakPolarHBondContact O-CB 3.47Å; I216-R219 PolarHBondContact O-N 3.42Å; I216-R219 VanDerWaalsContact O-N 3.15Å; I216-I220 HydrophobicContact CG2-CD1 3.73Å; I216-I220 HydrophobicContact CG2-CG1 4.4Å; I216-I220 WeakPolarHBondContact O-CG1 3.31Å; I216-I220 PolarHBondContact O-N 3.44Å
217	S	92.8	Very high	90	Very high	75 Å²	75	77.3 Å²	77.3	52%	0.524	44%	0.436	S	S	.	.	H	α-helix	trans	-60.2	-42.4	177.5	-61.5	0	0	0	0	111.7	S213 I220 Y221	S213-S217 WeakPolarHBondContact O-CB 2.98Å; S213-S217 PolarHBondContact O-N 2.77Å; S213-S217 PolarHBondContact O-OG 3.21Å; S217-I220 PolarHBondContact O-N 2.88Å; S217-Y221 WeakPolarHBondContact O-CB 3.46Å; S217-Y221 PolarHBondContact O-N 3.01Å
218	F	89.7	Confident	89.9	Confident	76 Å²	76	78.9 Å²	78.9	33%	0.333	44%	0.444	S	S	.	.	H	α-helix	trans	-64.2	-40.1	175.4	-177	-97.9	0	0	0	112.4	V214 T215 I216 Y221 K222 P236 F237	V214-F218 WeakPolarHBondContact O-CB 3.46Å; V214-F218 PolarHBondContact O-N 2.9Å; T215-F218 PolarHBondContact O-N 3.1Å; I216-F218 VanDerWaalsContact C-N 3.32Å; I216-F218 PolarHBondContact O-N 3.3Å; F218-Y221 PolarHBondContact O-N 2.88Å; F218-K222 HydrophobicContact CD1-CG 4.26Å; F218-K222 HydrophobicContact CE1-CG 3.89Å; F218-K222 HydrophobicContact CE2-CG 4.3Å; F218-K222 HydrophobicContact CZ-CG 3.9Å; F218-K222 VanDerWaalsContact O-CB 3.31Å; F218-K222 WeakPolarHBondContact O-CB 3.43Å; F218-K222 PolarHBondContact O-N 2.85Å; F218-P236 HydrophobicContact CD1-CG 4.5Å; F218-P236 HydrophobicContact CE1-CB 3.87Å; F218-P236 HydrophobicContact CE1-CG 4.28Å; F218-F237 HydrophobicContact CB-CZ 4.11Å; F218-F237 HydrophobicContact CD1-CD1 4.34Å; F218-F237 AromaticContact CD1-CE1 3.39Å; F218-F237 HydrophobicContact CD1-CE1 3.39Å; F218-F237 AromaticContact CD1-CE2 3.89Å; F218-F237 HydrophobicContact CD1-CE2 3.89Å; F218-F237 AromaticContact CD1-CZ 3.1Å; F218-F237 HydrophobicContact CD1-CZ 3.1Å; F218-F237 HydrophobicContact CE1-CD1 4.08Å; F218-F237 AromaticContact CE1-CE1 3.39Å; F218-F237 HydrophobicContact CE1-CE1 3.39Å; F218-F237 AromaticContact CE1-CZ 3.66Å; F218-F237 HydrophobicContact CE1-CZ 3.66Å; F218-F237 HydrophobicContact CG-CE1 4.33Å; F218-F237 AromaticContact CG-CZ 3.87Å; F218-F237 HydrophobicContact CG-CZ 3.87Å; F218-F237 HydrophobicContact CZ-CE1 4.38Å
219	R	86.8	Confident	89.6	Confident	56 Å²	56	82.3 Å²	82.3	21%	0.211	45%	0.452	C	S	.	.	H	α-helix	trans	-62	-46.1	175.2	-75.5	-84.7	-162.7	-134.1	9.5	111.7	T215 I216 G223 H235 F237	T215-R219 WeakPolarHBondContact O-CB 3.31Å; T215-R219 WeakPolarHBondContact O-CG 3.47Å; T215-R219 PolarHBondContact O-N 3.25Å; I216-R219 WeakPolarHBondContact O-CB 3.47Å; I216-R219 PolarHBondContact O-N 3.42Å; I216-R219 VanDerWaalsContact O-N 3.15Å; R219-G223 PolarHBondContact O-N 3.45Å; R219-H235 VanDerWaalsContact CD-CE1 3.45Å; R219-H235 WeakPolarHBondContact CD-CE1 3.46Å; R219-H235 VanDerWaalsContact CZ-CG 3.48Å; R219-H235 PolarHBondContact NE-CE1 3.32Å; R219-H235 PolarHBondContact NE-ND1 3.24Å; R219-H235 PolarHBondContact NE-NE2 3.43Å; R219-H235 PolarHBondContact NH1-CE1 3.31Å; R219-H235 VanDerWaalsContact NH1-CE1 3.34Å; R219-H235 VanDerWaalsContact NH1-CG 3.29Å; R219-H235 PolarHBondContact NH1-ND1 3.45Å; R219-H235 PolarHBondContact NH2-CD2 3.39Å; R219-H235 PolarHBondContact NH2-CE1 2.98Å; R219-H235 PolarHBondContact NH2-NE2 3.06Å; R219-F237 HydrophobicContact CG-CD2 4.34Å; R219-F237 HydrophobicContact CG-CE2 3.93Å; R219-F237 VanDerWaalsContact NH1-CB 3.33Å; R219-F237 VanDerWaalsContact NH2-CD2 3.32Å
220	I	90.2	Very high	88.9	Confident	106 Å²	106	86.8 Å²	86.8	54%	0.544	47%	0.466	S	S	.	.	H	α-helix	trans	-63.5	-48.7	176.9	-65.6	165.5	0	0	0	109.8	I216 S217 K222 G223 V224	I216-I220 HydrophobicContact CG2-CD1 3.73Å; I216-I220 HydrophobicContact CG2-CG1 4.4Å; I216-I220 WeakPolarHBondContact O-CG1 3.31Å; I216-I220 PolarHBondContact O-N 3.44Å; S217-I220 PolarHBondContact O-N 2.88Å; I220-K222 PolarHBondContact O-N 3.38Å; I220-G223 PolarHBondContact O-N 3.41Å; I220-G223 VanDerWaalsContact O-N 3.14Å; I220-V224 HydrophobicContact CG2-CG2 4.38Å; I220-V224 WeakPolarHBondContact O-CG2 3.27Å; I220-V224 PolarHBondContact O-N 3.27Å
221	Y	89.4	Confident	87.8	Confident	147 Å²	147	85.9 Å²	85.9	58%	0.576	46%	0.457	S	S	*	.	H	α-helix	trans	-56.2	-51.2	177.7	173.7	-102.4	0	0	0	111.9	S217 F218 G223 V224 I225	S217-Y221 WeakPolarHBondContact O-CB 3.46Å; S217-Y221 PolarHBondContact O-N 3.01Å; F218-Y221 PolarHBondContact O-N 2.88Å; Y221-G223 VanDerWaalsContact C-N 3.33Å; Y221-G223 PolarHBondContact O-N 3.47Å; Y221-V224 PolarHBondContact O-N 2.64Å; Y221-I225 HydrophobicContact CE1-CG1 4.12Å; Y221-I225 HydrophobicContact CE2-CD1 4.34Å; Y221-I225 HydrophobicContact CE2-CG1 4.11Å; Y221-I225 WeakPolarHBondContact O-CG1 3.39Å; Y221-I225 PolarHBondContact O-N 3.02Å
222	K	84.5	Confident	86.7	Confident	68 Å²	68	88 Å²	88	30%	0.296	47%	0.469	S	S	.	.	H	α-helix	trans	-62.7	-38.9	176	-85.4	-76	-165.6	167.9	0	112	F218 I220 I225 Q226 E233 P236	F218-K222 HydrophobicContact CD1-CG 4.26Å; F218-K222 HydrophobicContact CE1-CG 3.89Å; F218-K222 HydrophobicContact CE2-CG 4.3Å; F218-K222 HydrophobicContact CZ-CG 3.9Å; F218-K222 VanDerWaalsContact O-CB 3.31Å; F218-K222 WeakPolarHBondContact O-CB 3.43Å; F218-K222 PolarHBondContact O-N 2.85Å; I220-K222 PolarHBondContact O-N 3.38Å; K222-I225 PolarHBondContact O-N 2.9Å; K222-Q226 WeakPolarHBondContact O-CB 3.06Å; K222-Q226 PolarHBondContact O-N 2.68Å; K222-E233 IonicContact NZ-OE2 3.23Å; K222-P236 HydrophobicContact CB-CB 3.96Å; K222-P236 HydrophobicContact CB-CG 3.69Å; K222-P236 HydrophobicContact CD-CB 4.11Å; K222-P236 HydrophobicContact CG-CB 3.74Å; K222-P236 HydrophobicContact CG-CG 3.99Å
223	G	85.6	Confident	85.4	Confident	32 Å²	32	88.9 Å²	88.9	33%	0.33	47%	0.47	S	S	.	.	H	α-helix	trans	-63.3	-40	176.1	0	0	0	0	0	112.9	R219 I220 Y221 Q226 A227	R219-G223 PolarHBondContact O-N 3.45Å; I220-G223 PolarHBondContact O-N 3.41Å; I220-G223 VanDerWaalsContact O-N 3.14Å; Y221-G223 VanDerWaalsContact C-N 3.33Å; Y221-G223 PolarHBondContact O-N 3.47Å; G223-Q226 PolarHBondContact O-N 2.93Å; G223-A227 WeakPolarHBondContact O-CB 3.29Å; G223-A227 PolarHBondContact O-N 2.99Å
224	V	88.6	Confident	84.1	Confident	77 Å²	77	87.8 Å²	87.8	47%	0.467	47%	0.469	S	S	.	.	H	α-helix	trans	-65.8	-47.5	174	172.6	0	0	0	0	110.6	I220 Y221 Q226 A227 I228	I220-V224 HydrophobicContact CG2-CG2 4.38Å; I220-V224 WeakPolarHBondContact O-CG2 3.27Å; I220-V224 PolarHBondContact O-N 3.27Å; Y221-V224 PolarHBondContact O-N 2.64Å; V224-Q226 VanDerWaalsContact C-N 3.3Å; V224-Q226 PolarHBondContact O-N 3.34Å; V224-A227 PolarHBondContact O-N 3.35Å; V224-I228 HydrophobicContact CG1-CD1 3.69Å; V224-I228 HydrophobicContact CG1-CG1 4.45Å; V224-I228 VanDerWaalsContact O-CG1 3.25Å; V224-I228 WeakPolarHBondContact O-CG1 3.33Å; V224-I228 PolarHBondContact O-N 3.39Å
225	I	86	Confident	83.1	Confident	47 Å²	47	87.9 Å²	87.9	24%	0.241	46%	0.463	C	S	.	.	H	α-helix	trans	-59.9	-41.6	175.6	-66.4	-64.3	0	0	0	111.1	Y221 K222 A227 I228 Q229	Y221-I225 HydrophobicContact CE1-CG1 4.12Å; Y221-I225 HydrophobicContact CE2-CD1 4.34Å; Y221-I225 HydrophobicContact CE2-CG1 4.11Å; Y221-I225 WeakPolarHBondContact O-CG1 3.39Å; Y221-I225 PolarHBondContact O-N 3.02Å; K222-I225 PolarHBondContact O-N 2.9Å; I225-A227 PolarHBondContact O-N 2.99Å; I225-I228 PolarHBondContact O-N 3.19Å; I225-Q229 HydrophobicContact CG2-CG 4.26Å; I225-Q229 WeakPolarHBondContact O-CB 3.38Å; I225-Q229 WeakPolarHBondContact O-CG 3.4Å; I225-Q229 PolarHBondContact O-N 2.81Å
226	Q	83.2	Confident	82.3	Confident	62 Å²	62	87.4 Å²	87.4	29%	0.29	46%	0.461	S	S	.	.	H	α-helix	trans	-60.9	-44.7	177.6	-167.5	-175.9	1.9	0	0	111.7	K222 G223 V224 K230 S231 E233	K222-Q226 WeakPolarHBondContact O-CB 3.06Å; K222-Q226 PolarHBondContact O-N 2.68Å; G223-Q226 PolarHBondContact O-N 2.93Å; V224-Q226 VanDerWaalsContact C-N 3.3Å; V224-Q226 PolarHBondContact O-N 3.34Å; Q226-K230 PolarHBondContact O-N 2.9Å; Q226-S231 WeakPolarHBondContact CG-O 3.17Å; Q226-S231 PolarHBondContact NE2-O 3.14Å; Q226-S231 PolarHBondContact O-N 3.37Å; Q226-E233 VanDerWaalsContact CD-O 3.32Å; Q226-E233 PolarHBondContact NE2-O 2.63Å
227	A	85	Confident	81.2	Confident	77 Å²	77	85.3 Å²	85.3	64%	0.636	45%	0.448	S	S	*	.	H	α-helix	trans	-65.8	-40.2	176.8	0	0	0	0	0	112.5	G223 V224 I225	G223-A227 WeakPolarHBondContact O-CB 3.29Å; G223-A227 PolarHBondContact O-N 2.99Å; V224-A227 PolarHBondContact O-N 3.35Å; I225-A227 PolarHBondContact O-N 2.99Å
228	I	88.7	Confident	80.2	Confident	124 Å²	124	88.6 Å²	88.6	64%	0.636	45%	0.449	S	S	*	.	H	α-helix	trans	-67.5	-42.6	178	-67.9	166.4	0	0	0	111	V224 I225 K230	V224-I228 HydrophobicContact CG1-CD1 3.69Å; V224-I228 HydrophobicContact CG1-CG1 4.45Å; V224-I228 VanDerWaalsContact O-CG1 3.25Å; V224-I228 WeakPolarHBondContact O-CG1 3.33Å; V224-I228 PolarHBondContact O-N 3.39Å; I225-I228 PolarHBondContact O-N 3.19Å; I228-K230 VanDerWaalsContact C-N 3.31Å; I228-K230 PolarHBondContact O-N 2.89Å
229	Q	85.6	Confident	79.5	Confident	123 Å²	123	88.6 Å²	88.6	58%	0.575	46%	0.463	S	S	*	.	H	α-helix	trans	-83.4	-5.3	-176.1	-68.4	-177.9	-15.5	0	0	113.4	I225 S231	I225-Q229 HydrophobicContact CG2-CG 4.26Å; I225-Q229 WeakPolarHBondContact O-CB 3.38Å; I225-Q229 WeakPolarHBondContact O-CG 3.4Å; I225-Q229 PolarHBondContact O-N 2.81Å; Q229-S231 PolarHBondContact O-N 3.27Å
230	K	80.5	Confident	79	Confident	198 Å²	198	94.2 Å²	94.2	86%	0.861	49%	0.486	S	S	*	.	T	Hydrogen-bonded Turn	trans	46.7	31.5	-170	-67.4	175.4	174.2	163	0	111.8	Q226 I228	Q226-K230 PolarHBondContact O-N 2.9Å; I228-K230 VanDerWaalsContact C-N 3.31Å; I228-K230 PolarHBondContact O-N 2.89Å
231	S	71.3	Confident	78.2	Confident	30 Å²	30	95 Å²	95	21%	0.21	49%	0.491	C	S	.	.			trans	-90.5	126.7	-176.2	56.3	0	0	0	0	108.7	Q226 Q229 E233	Q226-S231 WeakPolarHBondContact CG-O 3.17Å; Q226-S231 PolarHBondContact NE2-O 3.14Å; Q226-S231 PolarHBondContact O-N 3.37Å; Q229-S231 PolarHBondContact O-N 3.27Å; S231-E233 PolarHBondContact O-N 3.09Å
232	D	70.2	Confident	77.6	Confident	155 Å²	155	93.9 Å²	93.9	83%	0.829	49%	0.49	S	S	*	.			trans	-83.3	50.1	172.3	-160.2	0.5	0	0	0	110.9	G234	D232-G234 PolarHBondContact O-N 3.3Å
233	E	65.7	Low	77.1	Confident	117 Å²	117	93.9 Å²	93.9	55%	0.547	50%	0.499	S	S	.	.			trans	-76.6	103.1	168.5	-74.1	-168.5	171.1	0	0	107.2	K222 Q226 S231	K222-E233 IonicContact NZ-OE2 3.23Å; Q226-E233 VanDerWaalsContact CD-O 3.32Å; Q226-E233 PolarHBondContact NE2-O 2.63Å; S231-E233 PolarHBondContact O-N 3.09Å
234	G	68.3	Low	76.3	Confident	39 Å²	39	100.2 Å²	100.2	40%	0.402	52%	0.52	S	S	.	.			trans	-52.4	172.9	177.2	0	0	0	0	0	113.8	D232	D232-G234 PolarHBondContact O-N 3.3Å
235	H	71.4	Confident	75.5	Confident	99 Å²	99	102.6 Å²	102.6	46%	0.458	54%	0.535	S	S	.	.			trans	-34.9	121.3	-171.8	-153.9	27.4	0	0	0	113.4	R219 F237 R238	R219-H235 VanDerWaalsContact CD-CE1 3.45Å; R219-H235 WeakPolarHBondContact CD-CE1 3.46Å; R219-H235 VanDerWaalsContact CZ-CG 3.48Å; R219-H235 PolarHBondContact NE-CE1 3.32Å; R219-H235 PolarHBondContact NE-ND1 3.24Å; R219-H235 PolarHBondContact NE-NE2 3.43Å; R219-H235 PolarHBondContact NH1-CE1 3.31Å; R219-H235 VanDerWaalsContact NH1-CE1 3.34Å; R219-H235 VanDerWaalsContact NH1-CG 3.29Å; R219-H235 PolarHBondContact NH1-ND1 3.45Å; R219-H235 PolarHBondContact NH2-CD2 3.39Å; R219-H235 PolarHBondContact NH2-CE1 2.98Å; R219-H235 PolarHBondContact NH2-NE2 3.06Å; H235-F237 PolarHBondContact O-N 3.04Å; H235-R238 HydrophobicContact CB-CB 4.3Å; H235-R238 WeakPolarHBondContact O-CB 2.97Å; H235-R238 PolarHBondContact O-N 2.73Å
236	P	73	Confident	75.1	Confident	40 Å²	40	103.4 Å²	103.4	26%	0.26	55%	0.548	S	S	.	.	T	Hydrogen-bonded Turn	trans	-68.5	-0.4	-167.1	26.9	-37.7	0	0	0	115.3	F218 K222	F218-P236 HydrophobicContact CD1-CG 4.5Å; F218-P236 HydrophobicContact CE1-CB 3.87Å; F218-P236 HydrophobicContact CE1-CG 4.28Å; K222-P236 HydrophobicContact CB-CB 3.96Å; K222-P236 HydrophobicContact CB-CG 3.69Å; K222-P236 HydrophobicContact CD-CB 4.11Å; K222-P236 HydrophobicContact CG-CB 3.74Å; K222-P236 HydrophobicContact CG-CG 3.99Å
237	F	69.7	Low	74.7	Confident	43 Å²	43	106.6 Å²	106.6	19%	0.189	57%	0.566	C	S	.	*	T	Hydrogen-bonded Turn	trans	-120.4	18.8	172.6	-54.7	-51.8	0	0	0	111.1	T215 F218 R219 H235 A239 Y240 L241	T215-F237 HydrophobicContact CG2-CE2 3.94Å; T215-F237 HydrophobicContact CG2-CZ 4.1Å; F218-F237 HydrophobicContact CB-CZ 4.11Å; F218-F237 HydrophobicContact CD1-CD1 4.34Å; F218-F237 AromaticContact CD1-CE1 3.39Å; F218-F237 HydrophobicContact CD1-CE1 3.39Å; F218-F237 AromaticContact CD1-CE2 3.89Å; F218-F237 HydrophobicContact CD1-CE2 3.89Å; F218-F237 AromaticContact CD1-CZ 3.1Å; F218-F237 HydrophobicContact CD1-CZ 3.1Å; F218-F237 HydrophobicContact CE1-CD1 4.08Å; F218-F237 AromaticContact CE1-CE1 3.39Å; F218-F237 HydrophobicContact CE1-CE1 3.39Å; F218-F237 AromaticContact CE1-CZ 3.66Å; F218-F237 HydrophobicContact CE1-CZ 3.66Å; F218-F237 HydrophobicContact CG-CE1 4.33Å; F218-F237 AromaticContact CG-CZ 3.87Å; F218-F237 HydrophobicContact CG-CZ 3.87Å; F218-F237 HydrophobicContact CZ-CE1 4.38Å; R219-F237 HydrophobicContact CG-CD2 4.34Å; R219-F237 HydrophobicContact CG-CE2 3.93Å; R219-F237 VanDerWaalsContact NH1-CB 3.33Å; R219-F237 VanDerWaalsContact NH2-CD2 3.32Å; H235-F237 PolarHBondContact O-N 3.04Å; F237-A239 VanDerWaalsContact C-N 3.29Å; F237-A239 PolarHBondContact O-N 2.63Å; F237-Y240 HydrophobicContact CB-CD2 4.34Å; F237-Y240 HydrophobicContact CD1-CD2 4.12Å; F237-Y240 CarbonylContact O-C 3.57Å; F237-Y240 WeakPolarHBondContact O-CA 3.4Å; F237-Y240 PolarHBondContact O-N 3.39Å; F237-L241 WeakPolarHBondContact O-CG 3.31Å; F237-L241 PolarHBondContact O-N 3.14Å
238	R	71.2	Confident	74.7	Confident	144 Å²	144	105.7 Å²	105.7	54%	0.543	56%	0.555	S	S	.	*	H	α-helix	trans	-57.4	-44.3	-179.1	-173.5	173.3	-176.7	138.1	10.8	111.2	H235 Y240 L241 E242	H235-R238 HydrophobicContact CB-CB 4.3Å; H235-R238 WeakPolarHBondContact O-CB 2.97Å; H235-R238 PolarHBondContact O-N 2.73Å; R238-Y240 PolarHBondContact O-N 3.39Å; R238-L241 PolarHBondContact O-N 2.88Å; R238-E242 HydrophobicContact CG-CG 4.08Å; R238-E242 WeakPolarHBondContact CG-OE1 3.22Å; R238-E242 IonicContact CZ-OE1 2.7Å; R238-E242 IonicContact NE-OE1 3.74Å; R238-E242 PolarHBondContact NE-OE1 2.82Å; R238-E242 IonicContact NH2-OE1 2.75Å; R238-E242 PolarHBondContact NH2-OE1 3.06Å; R238-E242 VanDerWaalsContact O-CB 3.27Å; R238-E242 WeakPolarHBondContact O-CB 3.35Å; R238-E242 VanDerWaalsContact O-CG 3.31Å; R238-E242 WeakPolarHBondContact O-CG 3.47Å; R238-E242 PolarHBondContact O-N 3.3Å
239	A	74.5	Confident	74.6	Confident	76 Å²	76	107 Å²	107	63%	0.628	56%	0.559	S	S	*	*	H	α-helix	trans	-59.2	-32.4	174.4	0	0	0	0	0	113.4	F237 S243	F237-A239 VanDerWaalsContact C-N 3.29Å; F237-A239 PolarHBondContact O-N 2.63Å; A239-S243 VanDerWaalsContact O-CB 3.28Å; A239-S243 WeakPolarHBondContact O-CB 3.3Å; A239-S243 PolarHBondContact O-N 2.98Å
240	Y	76.1	Confident	74.7	Confident	175 Å²	175	108.7 Å²	108.7	69%	0.686	57%	0.566	S	S	*	*	H	α-helix	trans	-81.7	-32.8	177	-66.9	-80	0	0	0	112.9	F237 R238	F237-Y240 HydrophobicContact CB-CD2 4.34Å; F237-Y240 HydrophobicContact CD1-CD2 4.12Å; F237-Y240 CarbonylContact O-C 3.57Å; F237-Y240 WeakPolarHBondContact O-CA 3.4Å; F237-Y240 PolarHBondContact O-N 3.39Å; R238-Y240 PolarHBondContact O-N 3.39Å
241	L	74.6	Confident	75.1	Confident	123 Å²	123	103.4 Å²	103.4	64%	0.644	55%	0.547	S	S	*	.	H	α-helix	trans	-75.1	-33	174.7	-70.3	174.1	0	0	0	112.3	F237 R238	F237-L241 WeakPolarHBondContact O-CG 3.31Å; F237-L241 PolarHBondContact O-N 3.14Å; R238-L241 PolarHBondContact O-N 2.88Å
242	E	75.3	Confident	75.9	Confident	122 Å²	122	105.5 Å²	105.5	57%	0.57	56%	0.558	S	S	*	*	H	α-helix	trans	-82.9	-21.1	175.5	-69.9	178.3	172.3	0	0	112.2	R238 E244	R238-E242 HydrophobicContact CG-CG 4.08Å; R238-E242 WeakPolarHBondContact CG-OE1 3.22Å; R238-E242 IonicContact CZ-OE1 2.7Å; R238-E242 IonicContact NE-OE1 3.74Å; R238-E242 PolarHBondContact NE-OE1 2.82Å; R238-E242 IonicContact NH2-OE1 2.75Å; R238-E242 PolarHBondContact NH2-OE1 3.06Å; R238-E242 VanDerWaalsContact O-CB 3.27Å; R238-E242 WeakPolarHBondContact O-CB 3.35Å; R238-E242 VanDerWaalsContact O-CG 3.31Å; R238-E242 WeakPolarHBondContact O-CG 3.47Å; R238-E242 PolarHBondContact O-N 3.3Å; E242-E244 PolarHBondContact O-N 2.74Å
243	S	74.7	Confident	76.9	Confident	69 Å²	69	103.6 Å²	103.6	48%	0.483	54%	0.544	S	S	.	.	S	Bend	trans	-63.2	111.1	168.7	-178.4	0	0	0	0	108	A239 V245	A239-S243 VanDerWaalsContact O-CB 3.28Å; A239-S243 WeakPolarHBondContact O-CB 3.3Å; A239-S243 PolarHBondContact O-N 2.98Å; S243-V245 WeakPolarHBondContact O-CG2 3.48Å; S243-V245 PolarHBondContact O-N 3.41Å
244	E	69.7	Low	78.2	Confident	164 Å²	164	105.1 Å²	105.1	77%	0.766	55%	0.549	S	S	*	.			trans	-62.8	100.7	176.1	-164.3	-178.6	177.6	0	0	108.9	E242 A246	E242-E244 PolarHBondContact O-N 2.74Å; E244-A246 HydrophobicContact CG-CB 3.54Å; E244-A246 PolarHBondContact O-N 3.35Å; E244-A246 VanDerWaalsContact O-N 3.07Å; E244-A246 WeakPolarHBondContact OE1-CB 3.13Å
245	V	70.5	Confident	79.2	Confident	128 Å²	128	110.9 Å²	110.9	78%	0.776	56%	0.56	S	S	*	*			trans	-75.2	19.9	170.8	-164.5	0	0	0	0	110.1	S243 I247	S243-V245 WeakPolarHBondContact O-CG2 3.48Å; S243-V245 PolarHBondContact O-N 3.41Å; V245-I247 PolarHBondContact O-N 2.75Å; V245-I247 VanDerWaalsContact O-N 3.09Å
246	A	77.8	Confident	80.2	Confident	63 Å²	63	108.7 Å²	108.7	52%	0.521	56%	0.556	S	S	.	*	P	Polyproline II helix	trans	-65.1	116.7	175.7	0	0	0	0	0	108.2	E244 S248	E244-A246 HydrophobicContact CG-CB 3.54Å; E244-A246 PolarHBondContact O-N 3.35Å; E244-A246 VanDerWaalsContact O-N 3.07Å; E244-A246 WeakPolarHBondContact OE1-CB 3.13Å; A246-S248 PolarHBondContact O-N 3.25Å
247	I	74.7	Confident	81.2	Confident	130 Å²	130	111.8 Å²	111.8	67%	0.667	57%	0.57	S	S	*	*	P	Polyproline II helix	trans	-63.9	124.7	166.6	-56.1	175.7	0	0	0	106	V245 E249 V252	V245-I247 PolarHBondContact O-N 2.75Å; V245-I247 VanDerWaalsContact O-N 3.09Å; I247-E249 PolarHBondContact O-N 2.97Å; I247-E249 VanDerWaalsContact O-N 3.11Å; I247-V252 HydrophobicContact CB-CG2 4.13Å; I247-V252 HydrophobicContact CG2-CG2 3.52Å
248	S	84.4	Confident	82.2	Confident	58 Å²	58	112.8 Å²	112.8	41%	0.406	58%	0.582	S	S	.	*	P	Polyproline II helix	trans	-49.3	120.5	179.5	174.2	0	0	0	0	110.8	A246 E250 L251 V252	A246-S248 PolarHBondContact O-N 3.25Å; S248-E250 PolarHBondContact O-N 2.94Å; S248-L251 WeakPolarHBondContact O-CB 3.25Å; S248-L251 PolarHBondContact O-N 3.46Å; S248-V252 PolarHBondContact O-N 3.2Å; S248-V252 VanDerWaalsContact O-N 3.11Å
249	E	87.4	Confident	83.3	Confident	152 Å²	152	108.2 Å²	108.2	71%	0.71	58%	0.576	S	S	*	*	H	α-helix	trans	-56.4	-33.6	-179.1	-65.6	-171.9	173.2	0	0	111.9	I247 L251 V252 Q253	I247-E249 PolarHBondContact O-N 2.97Å; I247-E249 VanDerWaalsContact O-N 3.11Å; E249-L251 VanDerWaalsContact C-N 3.34Å; E249-L251 PolarHBondContact O-N 2.95Å; E249-V252 PolarHBondContact O-N 2.83Å; E249-Q253 WeakPolarHBondContact O-CB 3.28Å; E249-Q253 WeakPolarHBondContact O-CG 3.42Å; E249-Q253 PolarHBondContact O-N 3.07Å
250	E	88.5	Confident	84.3	Confident	157 Å²	157	109.1 Å²	109.1	73%	0.734	57%	0.569	S	S	*	*	H	α-helix	trans	-63.1	-39.3	176.5	-63.3	-171.2	174	0	0	112.3	S248 K254	S248-E250 PolarHBondContact O-N 2.94Å; E250-K254 WeakPolarHBondContact O-CB 3.39Å; E250-K254 PolarHBondContact O-N 2.91Å
251	L	87.9	Confident	85.2	Confident	87 Å²	87	102.8 Å²	102.8	46%	0.455	56%	0.558	S	S	.	*	H	α-helix	trans	-67.3	-47.5	175.1	-66.2	179	0	0	0	109.9	S248 E249 Q253 K254 Y255	S248-L251 WeakPolarHBondContact O-CB 3.25Å; S248-L251 PolarHBondContact O-N 3.46Å; E249-L251 VanDerWaalsContact C-N 3.34Å; E249-L251 PolarHBondContact O-N 2.95Å; L251-Q253 PolarHBondContact O-N 3.41Å; L251-K254 PolarHBondContact O-N 3Å; L251-Y255 HydrophobicContact CB-CD2 4.42Å; L251-Y255 HydrophobicContact CB-CE2 4.47Å; L251-Y255 HydrophobicContact CD2-CE2 4.37Å; L251-Y255 WeakPolarHBondContact O-CD2 3.44Å; L251-Y255 PolarHBondContact O-N 3.28Å
252	V	89.2	Confident	86.2	Confident	74 Å²	74	102.8 Å²	102.8	45%	0.448	55%	0.554	S	S	.	*	H	α-helix	trans	-59.5	-46.8	178.3	-179.7	0	0	0	0	110.5	I247 S248 E249 Y255 S256	I247-V252 HydrophobicContact CB-CG2 4.13Å; I247-V252 HydrophobicContact CG2-CG2 3.52Å; S248-V252 PolarHBondContact O-N 3.2Å; S248-V252 VanDerWaalsContact O-N 3.11Å; E249-V252 PolarHBondContact O-N 2.83Å; V252-Y255 PolarHBondContact O-N 3.3Å; V252-S256 WeakPolarHBondContact O-CA 3.14Å; V252-S256 WeakPolarHBondContact O-CB 3.44Å; V252-S256 PolarHBondContact O-N 3.34Å; V252-S256 PolarHBondContact O-OG 2.92Å
253	Q	91.5	Very high	87.2	Confident	115 Å²	115	100.6 Å²	100.6	54%	0.537	55%	0.549	S	S	.	.	H	α-helix	trans	-64.4	-40.7	177.9	-74.9	-165.9	14.5	0	0	112.6	E249 L251 S256 N257	E249-Q253 WeakPolarHBondContact O-CB 3.28Å; E249-Q253 WeakPolarHBondContact O-CG 3.42Å; E249-Q253 PolarHBondContact O-N 3.07Å; L251-Q253 PolarHBondContact O-N 3.41Å; Q253-S256 WeakPolarHBondContact CA-OG 3.27Å; Q253-S256 PolarHBondContact O-OG 3.36Å; Q253-N257 WeakPolarHBondContact O-CB 3.13Å; Q253-N257 PolarHBondContact O-N 2.92Å; Q253-N257 PolarHBondContact O-ND2 2.82Å
254	K	91.1	Very high	88.2	Confident	149 Å²	149	101.6 Å²	101.6	65%	0.648	55%	0.549	S	S	*	.	H	α-helix	trans	-63.1	-48.2	177.6	-178.2	179.6	179.1	-179.7	0	111.4	E250 L251 S258	E250-K254 WeakPolarHBondContact O-CB 3.39Å; E250-K254 PolarHBondContact O-N 2.91Å; L251-K254 PolarHBondContact O-N 3Å; K254-S258 WeakPolarHBondContact O-CB 3.45Å; K254-S258 PolarHBondContact O-N 2.82Å
255	Y	89.6	Confident	89.4	Confident	161 Å²	161	97.6 Å²	97.6	63%	0.631	54%	0.539	S	S	*	.	H	α-helix	trans	-72.7	-37.7	179.3	-72.3	-68.4	0	0	0	111.9	L251 V252 S258 A259	L251-Y255 HydrophobicContact CB-CD2 4.42Å; L251-Y255 HydrophobicContact CB-CE2 4.47Å; L251-Y255 HydrophobicContact CD2-CE2 4.37Å; L251-Y255 WeakPolarHBondContact O-CD2 3.44Å; L251-Y255 PolarHBondContact O-N 3.28Å; V252-Y255 PolarHBondContact O-N 3.3Å; Y255-S258 PolarHBondContact O-N 2.77Å; Y255-A259 WeakPolarHBondContact O-CB 3.45Å; Y255-A259 PolarHBondContact O-N 3.32Å
256	S	93.6	Very high	90.5	Very high	53 Å²	53	95.3 Å²	95.3	37%	0.371	53%	0.525	S	S	.	.	H	α-helix	trans	-68.6	-43.8	179.1	72.7	0	0	0	0	111.5	V252 Q253 S258 A259 L260	V252-S256 WeakPolarHBondContact O-CA 3.14Å; V252-S256 WeakPolarHBondContact O-CB 3.44Å; V252-S256 PolarHBondContact O-N 3.34Å; V252-S256 PolarHBondContact O-OG 2.92Å; Q253-S256 WeakPolarHBondContact CA-OG 3.27Å; Q253-S256 PolarHBondContact O-OG 3.36Å; S256-S258 VanDerWaalsContact C-N 3.34Å; S256-S258 PolarHBondContact O-N 3.24Å; S256-A259 PolarHBondContact O-N 2.68Å; S256-L260 WeakPolarHBondContact O-CA 3.17Å; S256-L260 WeakPolarHBondContact O-CB 3.32Å; S256-L260 PolarHBondContact O-N 3.42Å
257	N	92.6	Very high	91.4	Very high	104 Å²	104	96.3 Å²	96.3	56%	0.556	52%	0.521	S	S	*	.	H	α-helix	trans	-63.6	-41.2	176.9	-75	-38.5	0	0	0	111.5	Q253 G261	Q253-N257 WeakPolarHBondContact O-CB 3.13Å; Q253-N257 PolarHBondContact O-N 2.92Å; Q253-N257 PolarHBondContact O-ND2 2.82Å; N257-G261 PolarHBondContact O-N 3.38Å
258	S	92	Very high	92.3	Very high	64 Å²	64	97.5 Å²	97.5	45%	0.448	52%	0.521	S	S	.	.	H	α-helix	trans	-65.8	-49.3	175.5	-179.5	0	0	0	0	111.5	K254 Y255 S256 L260 G261 H262	K254-S258 WeakPolarHBondContact O-CB 3.45Å; K254-S258 PolarHBondContact O-N 2.82Å; Y255-S258 PolarHBondContact O-N 2.77Å; S256-S258 VanDerWaalsContact C-N 3.34Å; S256-S258 PolarHBondContact O-N 3.24Å; S258-L260 PolarHBondContact O-N 2.81Å; S258-G261 PolarHBondContact O-N 3.45Å; S258-H262 PolarHBondContact O-CD2 3.36Å; S258-H262 PolarHBondContact O-N 2.94Å
259	A	94.4	Very high	92.7	Very high	49 Å²	49	98.5 Å²	98.5	41%	0.405	52%	0.52	S	S	.	.	H	α-helix	trans	-61.9	-44.5	178.7	0	0	0	0	0	111.5	Y255 S256 G261 H262 V263	Y255-A259 WeakPolarHBondContact O-CB 3.45Å; Y255-A259 PolarHBondContact O-N 3.32Å; S256-A259 PolarHBondContact O-N 2.68Å; A259-G261 VanDerWaalsContact C-N 3.34Å; A259-G261 PolarHBondContact O-N 3.22Å; A259-H262 PolarHBondContact O-N 2.83Å; A259-V263 WeakPolarHBondContact O-CB 3.19Å; A259-V263 VanDerWaalsContact O-CG2 3.25Å; A259-V263 WeakPolarHBondContact O-CG2 3.22Å; A259-V263 PolarHBondContact O-N 2.81Å
260	L	94.7	Very high	92.9	Very high	94 Å²	94	95.3 Å²	95.3	49%	0.492	51%	0.507	S	S	.	.	H	α-helix	trans	-63.8	-39.6	178.1	-173.3	64.5	0	0	0	111.2	S256 S258 N264	S256-L260 WeakPolarHBondContact O-CA 3.17Å; S256-L260 WeakPolarHBondContact O-CB 3.32Å; S256-L260 PolarHBondContact O-N 3.42Å; S258-L260 PolarHBondContact O-N 2.81Å; L260-N264 WeakPolarHBondContact CG-ND2 3.15Å; L260-N264 WeakPolarHBondContact O-CB 3.42Å; L260-N264 PolarHBondContact O-N 3.49Å; L260-N264 PolarHBondContact O-ND2 2.85Å
261	G	94.6	Very high	93.2	Very high	43 Å²	43	95.5 Å²	95.5	44%	0.443	50%	0.501	S	S	.	.	H	α-helix	trans	-58.3	-46.8	172	0	0	0	0	0	112.3	N257 S258 A259 S265	N257-G261 PolarHBondContact O-N 3.38Å; S258-G261 PolarHBondContact O-N 3.45Å; A259-G261 VanDerWaalsContact C-N 3.34Å; A259-G261 PolarHBondContact O-N 3.22Å; G261-S265 WeakPolarHBondContact O-CB 3.47Å; G261-S265 PolarHBondContact O-N 3.21Å
262	H	95.1	Very high	93.5	Very high	123 Å²	123	94.9 Å²	94.9	57%	0.569	49%	0.493	S	S	*	.	H	α-helix	trans	-65.9	-50	176.7	-70.2	-60.2	0	0	0	112.4	S258 A259 N264 S265 T266	S258-H262 PolarHBondContact O-CD2 3.36Å; S258-H262 PolarHBondContact O-N 2.94Å; A259-H262 PolarHBondContact O-N 2.83Å; H262-N264 PolarHBondContact O-N 3.39Å; H262-S265 WeakPolarHBondContact O-CB 3.27Å; H262-S265 PolarHBondContact O-N 3.38Å; H262-T266 WeakPolarHBondContact O-CB 3.43Å; H262-T266 PolarHBondContact O-N 2.76Å; H262-T266 PolarHBondContact O-OG1 3.4Å
263	V	96.5	Very high	93.7	Very high	76 Å²	76	92.2 Å²	92.2	46%	0.461	48%	0.476	S	S	.	.	H	α-helix	trans	-60.6	-45.6	-179.5	170.2	0	0	0	0	110.9	A259 S265 T266 I267	A259-V263 WeakPolarHBondContact O-CB 3.19Å; A259-V263 VanDerWaalsContact O-CG2 3.25Å; A259-V263 WeakPolarHBondContact O-CG2 3.22Å; A259-V263 PolarHBondContact O-N 2.81Å; V263-S265 VanDerWaalsContact C-N 3.35Å; V263-S265 PolarHBondContact O-N 2.88Å; V263-T266 PolarHBondContact O-N 3.31Å; V263-I267 HydrophobicContact CG1-CD1 3.63Å; V263-I267 HydrophobicContact CG1-CG1 4.31Å; V263-I267 WeakPolarHBondContact O-CB 3.15Å; V263-I267 VanDerWaalsContact O-CG1 3.28Å; V263-I267 WeakPolarHBondContact O-CG1 3.34Å; V263-I267 PolarHBondContact O-N 2.87Å
264	N	95.6	Very high	93.6	Very high	89 Å²	89	95.5 Å²	95.5	48%	0.476	49%	0.489	S	S	.	.	H	α-helix	trans	-63.6	-40.7	176.7	-75.7	-25.8	0	0	0	112	L260 H262 I267 K268	L260-N264 WeakPolarHBondContact CG-ND2 3.15Å; L260-N264 WeakPolarHBondContact O-CB 3.42Å; L260-N264 PolarHBondContact O-N 3.49Å; L260-N264 PolarHBondContact O-ND2 2.85Å; H262-N264 PolarHBondContact O-N 3.39Å; N264-I267 PolarHBondContact O-N 3.45Å; N264-K268 VanDerWaalsContact O-CB 3.31Å; N264-K268 WeakPolarHBondContact O-CB 3.49Å; N264-K268 PolarHBondContact O-N 3.11Å
265	S	95.1	Very high	93.4	Very high	80 Å²	80	94.5 Å²	94.5	56%	0.559	49%	0.49	S	S	*	.	H	α-helix	trans	-62.1	-44.4	174.6	-169.3	0	0	0	0	111.3	G261 H262 V263 K268 E269	G261-S265 WeakPolarHBondContact O-CB 3.47Å; G261-S265 PolarHBondContact O-N 3.21Å; H262-S265 WeakPolarHBondContact O-CB 3.27Å; H262-S265 PolarHBondContact O-N 3.38Å; V263-S265 VanDerWaalsContact C-N 3.35Å; V263-S265 PolarHBondContact O-N 2.88Å; S265-K268 PolarHBondContact O-N 3.09Å; S265-E269 WeakPolarHBondContact O-CB 3.41Å; S265-E269 PolarHBondContact O-N 3.17Å
266	T	94.1	Very high	93.4	Very high	80 Å²	80	90 Å²	90	49%	0.491	48%	0.479	S	S	.	.	H	α-helix	trans	-62.9	-48.7	177.2	-62.6	0	0	0	0	110.9	H262 V263 K268 E269 L270	H262-T266 WeakPolarHBondContact O-CB 3.43Å; H262-T266 PolarHBondContact O-N 2.76Å; H262-T266 PolarHBondContact O-OG1 3.4Å; V263-T266 PolarHBondContact O-N 3.31Å; T266-K268 VanDerWaalsContact C-N 3.31Å; T266-K268 PolarHBondContact O-N 3.26Å; T266-E269 PolarHBondContact O-N 3.49Å; T266-E269 VanDerWaalsContact O-N 3.15Å; T266-L270 HydrophobicContact CG2-CD1 3.4Å; T266-L270 WeakPolarHBondContact O-CD1 3.42Å; T266-L270 PolarHBondContact O-N 2.86Å
267	I	96.1	Very high	93.2	Very high	85 Å²	85	93.2 Å²	93.2	44%	0.436	49%	0.492	S	S	.	.	H	α-helix	trans	-60.2	-41.4	177.5	-69.4	168	0	0	0	111.3	V263 N264 E269 L270 R271	V263-I267 HydrophobicContact CG1-CD1 3.63Å; V263-I267 HydrophobicContact CG1-CG1 4.31Å; V263-I267 WeakPolarHBondContact O-CB 3.15Å; V263-I267 VanDerWaalsContact O-CG1 3.28Å; V263-I267 WeakPolarHBondContact O-CG1 3.34Å; V263-I267 PolarHBondContact O-N 2.87Å; N264-I267 PolarHBondContact O-N 3.45Å; I267-E269 VanDerWaalsContact C-N 3.32Å; I267-E269 PolarHBondContact O-N 2.8Å; I267-L270 PolarHBondContact O-N 3.17Å; I267-R271 WeakPolarHBondContact O-CB 3.29Å; I267-R271 PolarHBondContact O-N 3.28Å
268	K	94.4	Very high	93	Very high	155 Å²	155	90.8 Å²	90.8	67%	0.674	48%	0.479	S	S	*	.	H	α-helix	trans	-63	-41	176.9	-172.9	175.9	179.3	178.9	0	111.3	N264 S265 T266 R271 R272	N264-K268 VanDerWaalsContact O-CB 3.31Å; N264-K268 WeakPolarHBondContact O-CB 3.49Å; N264-K268 PolarHBondContact O-N 3.11Å; S265-K268 PolarHBondContact O-N 3.09Å; T266-K268 VanDerWaalsContact C-N 3.31Å; T266-K268 PolarHBondContact O-N 3.26Å; K268-R271 WeakPolarHBondContact O-CB 3.36Å; K268-R271 PolarHBondContact O-N 3.4Å; K268-R272 PolarHBondContact O-N 2.81Å
269	E	92.3	Very high	93	Very high	79 Å²	79	94 Å²	94	37%	0.369	49%	0.49	S	S	.	.	H	α-helix	trans	-68.9	-46.4	176.3	-162	57.6	-154.8	0	0	111.3	S265 T266 I267 R271 R272 L273	S265-E269 WeakPolarHBondContact O-CB 3.41Å; S265-E269 PolarHBondContact O-N 3.17Å; T266-E269 PolarHBondContact O-N 3.49Å; T266-E269 VanDerWaalsContact O-N 3.15Å; I267-E269 VanDerWaalsContact C-N 3.32Å; I267-E269 PolarHBondContact O-N 2.8Å; E269-R271 VanDerWaalsContact C-N 3.25Å; E269-R271 PolarHBondContact O-N 3.27Å; E269-R272 WeakPolarHBondContact O-CA 3.28Å; E269-R272 WeakPolarHBondContact O-CB 3.03Å; E269-R272 PolarHBondContact O-N 3.5Å; E269-R272 IonicContact OE1-NH1 3.41Å; E269-R272 PolarHBondContact OE1-NH1 2.97Å; E269-L273 HydrophobicContact CG-CD1 3.85Å; E269-L273 WeakPolarHBondContact O-CB 3.08Å; E269-L273 VanDerWaalsContact O-CD1 3.24Å; E269-L273 WeakPolarHBondContact O-CD1 3.5Å; E269-L273 PolarHBondContact O-N 3.4Å; E269-L273 WeakPolarHBondContact OE1-CD1 3.08Å
270	L	92.9	Very high	92.9	Very high	85 Å²	85	96 Å²	96	45%	0.445	50%	0.497	S	S	.	.	H	α-helix	trans	-56.5	-41.3	173.8	-89.4	83.3	0	0	0	111.7	T266 I267 L273 F274	T266-L270 HydrophobicContact CG2-CD1 3.4Å; T266-L270 WeakPolarHBondContact O-CD1 3.42Å; T266-L270 PolarHBondContact O-N 2.86Å; I267-L270 PolarHBondContact O-N 3.17Å; L270-L273 PolarHBondContact O-N 2.78Å; L270-F274 VanDerWaalsContact O-CB 3.24Å; L270-F274 WeakPolarHBondContact O-CB 3.45Å; L270-F274 PolarHBondContact O-N 3.39Å
271	R	93.6	Very high	92.6	Very high	161 Å²	161	93.8 Å²	93.8	61%	0.608	49%	0.486	S	S	*	.	H	α-helix	trans	-59.4	-49.2	174.4	-177.8	-174.4	-61	176.4	0.9	110.8	I267 K268 E269 L273 F274 L275	I267-R271 WeakPolarHBondContact O-CB 3.29Å; I267-R271 PolarHBondContact O-N 3.28Å; K268-R271 WeakPolarHBondContact O-CB 3.36Å; K268-R271 PolarHBondContact O-N 3.4Å; E269-R271 VanDerWaalsContact C-N 3.25Å; E269-R271 PolarHBondContact O-N 3.27Å; R271-L273 VanDerWaalsContact C-N 3.34Å; R271-L273 PolarHBondContact O-N 3.06Å; R271-F274 PolarHBondContact O-N 3.08Å; R271-L275 HydrophobicContact CG-CD1 3.48Å; R271-L275 VanDerWaalsContact CG-CD1 3.48Å; R271-L275 WeakPolarHBondContact O-CB 3.24Å; R271-L275 WeakPolarHBondContact O-CD1 3.35Å; R271-L275 PolarHBondContact O-N 3.38Å
272	R	93.7	Very high	92.6	Very high	73 Å²	73	92.7 Å²	92.7	28%	0.275	47%	0.472	S	S	.	.	H	α-helix	trans	-58	-44.9	177.3	-175.6	-175.3	169.1	-117.5	-5	111.9	K268 E269 V276 D277 D278 D281	K268-R272 PolarHBondContact O-N 2.81Å; E269-R272 WeakPolarHBondContact O-CA 3.28Å; E269-R272 WeakPolarHBondContact O-CB 3.03Å; E269-R272 PolarHBondContact O-N 3.5Å; E269-R272 IonicContact OE1-NH1 3.41Å; E269-R272 PolarHBondContact OE1-NH1 2.97Å; R272-V276 PolarHBondContact O-N 3.29Å; R272-D277 HydrophobicContact CG-CB 3.58Å; R272-D277 WeakPolarHBondContact CG-OD2 3.18Å; R272-D277 IonicContact NE-OD2 3.4Å; R272-D277 PolarHBondContact NE-OD2 3.28Å; R272-D277 WeakPolarHBondContact O-CB 3.17Å; R272-D277 PolarHBondContact O-N 3.28Å; R272-D278 IonicContact NH2-OD2 3.51Å; R272-D281 IonicContact CZ-OD2 2.95Å; R272-D281 IonicContact NH1-OD2 2.92Å; R272-D281 PolarHBondContact NH1-OD2 2.97Å; R272-D281 IonicContact NH2-OD2 3.55Å; R272-D281 PolarHBondContact NH2-OD2 3.35Å
273	L	93.4	Very high	92.5	Very high	19 Å²	19	92.2 Å²	92.2	10%	0.099	47%	0.473	C	S	.	.	H	α-helix	trans	-68.7	-40.5	179.9	-89.5	58	0	0	0	112.3	E269 L270 R271 V276 D281 S282 F285	E269-L273 HydrophobicContact CG-CD1 3.85Å; E269-L273 WeakPolarHBondContact O-CB 3.08Å; E269-L273 VanDerWaalsContact O-CD1 3.24Å; E269-L273 WeakPolarHBondContact O-CD1 3.5Å; E269-L273 PolarHBondContact O-N 3.4Å; E269-L273 WeakPolarHBondContact OE1-CD1 3.08Å; L270-L273 PolarHBondContact O-N 2.78Å; R271-L273 VanDerWaalsContact C-N 3.34Å; R271-L273 PolarHBondContact O-N 3.06Å; L273-V276 PolarHBondContact O-N 3.45Å; L273-D281 HydrophobicContact CD1-CB 4.34Å; L273-S282 VanDerWaalsContact O-CB 3.28Å; L273-S282 WeakPolarHBondContact O-CB 3.31Å; L273-S282 PolarHBondContact O-OG 3.01Å; L273-F285 HydrophobicContact CD2-CB 3.51Å; L273-F285 HydrophobicContact CD2-CD1 4.25Å; L273-F285 HydrophobicContact CD2-CD2 3.71Å; L273-F285 HydrophobicContact CD2-CE2 4.49Å; L273-F285 HydrophobicContact CD2-CG 3.57Å; L273-F285 HydrophobicContact CG-CB 4.22Å; L273-F285 HydrophobicContact CG-CG 4.48Å
274	F	89.9	Confident	92.2	Very high	183 Å²	183	95 Å²	95	80%	0.803	48%	0.479	S	S	*	.	H	α-helix	trans	-75.4	-35.7	-179.8	-165.3	-95.5	0	0	0	112.6	L270 R271 V276	L270-F274 VanDerWaalsContact O-CB 3.24Å; L270-F274 WeakPolarHBondContact O-CB 3.45Å; L270-F274 PolarHBondContact O-N 3.39Å; R271-F274 PolarHBondContact O-N 3.08Å; F274-V276 PolarHBondContact O-N 3.29Å
275	L	87.9	Confident	92.1	Very high	128 Å²	128	93.9 Å²	93.9	67%	0.67	47%	0.47	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.1	-2.4	168.6	-89.5	127.5	0	0	0	113.2	R271 D277	R271-L275 HydrophobicContact CG-CD1 3.48Å; R271-L275 VanDerWaalsContact CG-CD1 3.48Å; R271-L275 WeakPolarHBondContact O-CB 3.24Å; R271-L275 WeakPolarHBondContact O-CD1 3.35Å; R271-L275 PolarHBondContact O-N 3.38Å; L275-D277 PolarHBondContact O-N 3.11Å
276	V	89	Confident	92	Very high	67 Å²	67	92.5 Å²	92.5	41%	0.406	46%	0.463	S	S	.	.	T	Hydrogen-bonded Turn	trans	52.5	39.8	-179.3	-159.8	0	0	0	0	111.2	R272 L273 F274 D278 L279	R272-V276 PolarHBondContact O-N 3.29Å; L273-V276 PolarHBondContact O-N 3.45Å; F274-V276 PolarHBondContact O-N 3.29Å; V276-D278 PolarHBondContact O-N 2.94Å; V276-L279 HydrophobicContact CG1-CB 4.37Å; V276-L279 HydrophobicContact CG1-CD1 3.72Å
277	D	88.9	Confident	92.1	Very high	121 Å²	121	92.4 Å²	92.4	65%	0.647	46%	0.462	S	S	*	.	S	Bend	trans	-60.5	-31.4	174.7	-175.6	50.6	0	0	0	110.6	R272 L275	R272-D277 HydrophobicContact CG-CB 3.58Å; R272-D277 WeakPolarHBondContact CG-OD2 3.18Å; R272-D277 IonicContact NE-OD2 3.4Å; R272-D277 PolarHBondContact NE-OD2 3.28Å; R272-D277 WeakPolarHBondContact O-CB 3.17Å; R272-D277 PolarHBondContact O-N 3.28Å; L275-D277 PolarHBondContact O-N 3.11Å
278	D	89.7	Confident	92	Very high	53 Å²	53	93.1 Å²	93.1	28%	0.283	47%	0.467	S	S	.	.	S	Bend	trans	-125.4	113.3	166.9	-172.9	-57.4	0	0	0	110	R272 V276 V280 D281 S282	R272-D278 IonicContact NH2-OD2 3.51Å; V276-D278 PolarHBondContact O-N 2.94Å; D278-V280 VanDerWaalsContact C-N 3.27Å; D278-V280 PolarHBondContact O-N 3.44Å; D278-V280 WeakPolarHBondContact OD1-CA 3.35Å; D278-V280 WeakPolarHBondContact OD1-CB 3.4Å; D278-V280 PolarHBondContact OD1-N 3.45Å; D278-D281 HydrophobicContact CB-CB 3.98Å; D278-D281 PolarHBondContact O-N 3.18Å; D278-D281 PolarHBondContact OD1-N 2.77Å; D278-S282 WeakPolarHBondContact O-CB 3.34Å; D278-S282 PolarHBondContact O-N 3.27Å
279	L	90.2	Very high	92	Very high	130 Å²	130	89 Å²	89	68%	0.681	45%	0.45	S	S	*	.	H	α-helix	trans	-61.5	-36	-178.5	-173.7	72.1	0	0	0	112	V276 L283	V276-L279 HydrophobicContact CG1-CB 4.37Å; V276-L279 HydrophobicContact CG1-CD1 3.72Å; L279-L283 WeakPolarHBondContact O-CB 3.24Å; L279-L283 PolarHBondContact O-N 2.86Å
280	V	92.1	Very high	92	Very high	92 Å²	92	94 Å²	94	56%	0.558	47%	0.466	S	S	*	.	H	α-helix	trans	-74.4	-45	-176.9	178.1	0	0	0	0	110	D278 L283 K284	D278-V280 VanDerWaalsContact C-N 3.27Å; D278-V280 PolarHBondContact O-N 3.44Å; D278-V280 WeakPolarHBondContact OD1-CA 3.35Å; D278-V280 WeakPolarHBondContact OD1-CB 3.4Å; D278-V280 PolarHBondContact OD1-N 3.45Å; V280-L283 PolarHBondContact O-N 2.98Å; V280-K284 HydrophobicContact CG1-CD 3.93Å; V280-K284 WeakPolarHBondContact O-CB 3.39Å; V280-K284 WeakPolarHBondContact O-CD 3.49Å; V280-K284 WeakPolarHBondContact O-CG 3.37Å; V280-K284 PolarHBondContact O-N 2.91Å
281	D	90.5	Very high	92.1	Very high	48 Å²	48	93.5 Å²	93.5	26%	0.257	47%	0.467	S	S	.	.	H	α-helix	trans	-65.6	-42.6	176.1	-71.2	-21.7	0	0	0	111.3	R272 L273 D278 K284 F285	R272-D281 IonicContact CZ-OD2 2.95Å; R272-D281 IonicContact NH1-OD2 2.92Å; R272-D281 PolarHBondContact NH1-OD2 2.97Å; R272-D281 IonicContact NH2-OD2 3.55Å; R272-D281 PolarHBondContact NH2-OD2 3.35Å; L273-D281 HydrophobicContact CD1-CB 4.34Å; D278-D281 HydrophobicContact CB-CB 3.98Å; D278-D281 PolarHBondContact O-N 3.18Å; D278-D281 PolarHBondContact OD1-N 2.77Å; D281-K284 PolarHBondContact O-N 2.83Å; D281-F285 WeakPolarHBondContact O-CB 3.41Å; D281-F285 PolarHBondContact O-N 3.49Å
282	S	92.8	Very high	92	Very high	20 Å²	20	91.9 Å²	91.9	14%	0.14	46%	0.464	C	S	.	.	H	α-helix	trans	-62.5	-43.5	175.6	-172.2	0	0	0	0	112	L273 D278 F285 A286	L273-S282 VanDerWaalsContact O-CB 3.28Å; L273-S282 WeakPolarHBondContact O-CB 3.31Å; L273-S282 PolarHBondContact O-OG 3.01Å; D278-S282 WeakPolarHBondContact O-CB 3.34Å; D278-S282 PolarHBondContact O-N 3.27Å; S282-F285 PolarHBondContact O-N 2.86Å; S282-A286 WeakPolarHBondContact O-CB 3.2Å; S282-A286 PolarHBondContact O-N 3.46Å
283	L	93	Very high	91.8	Very high	113 Å²	113	92.7 Å²	92.7	59%	0.592	48%	0.477	S	S	*	.	H	α-helix	trans	-64.2	-42.2	175.4	-179	63	0	0	0	111.9	L279 V280 F285 A286 V287	L279-L283 WeakPolarHBondContact O-CB 3.24Å; L279-L283 PolarHBondContact O-N 2.86Å; V280-L283 PolarHBondContact O-N 2.98Å; L283-F285 VanDerWaalsContact C-N 3.3Å; L283-F285 PolarHBondContact O-N 3.18Å; L283-A286 PolarHBondContact O-N 3.23Å; L283-V287 HydrophobicContact CD1-CG2 4.47Å; L283-V287 WeakPolarHBondContact O-CG2 3.45Å; L283-V287 PolarHBondContact O-N 2.82Å
284	K	91.5	Very high	91.6	Very high	135 Å²	135	99.1 Å²	99.1	59%	0.587	50%	0.501	S	S	*	.	H	α-helix	trans	-61.9	-41.1	175.9	-72.4	162.9	78.9	-169.2	0	111.1	V280 D281 L288	V280-K284 HydrophobicContact CG1-CD 3.93Å; V280-K284 WeakPolarHBondContact O-CB 3.39Å; V280-K284 WeakPolarHBondContact O-CD 3.49Å; V280-K284 WeakPolarHBondContact O-CG 3.37Å; V280-K284 PolarHBondContact O-N 2.91Å; D281-K284 PolarHBondContact O-N 2.83Å; K284-L288 VanDerWaalsContact O-CB 3.31Å; K284-L288 WeakPolarHBondContact O-CB 3.01Å; K284-L288 PolarHBondContact O-N 3.1Å
285	F	93.2	Very high	91.5	Very high	64 Å²	64	92.9 Å²	92.9	28%	0.281	48%	0.478	S	S	.	.	H	α-helix	trans	-64.7	-42.4	174	179.6	-105.4	0	0	0	112.3	L273 D281 S282 L283 V287 L288 M289	L273-F285 HydrophobicContact CD2-CB 3.51Å; L273-F285 HydrophobicContact CD2-CD1 4.25Å; L273-F285 HydrophobicContact CD2-CD2 3.71Å; L273-F285 HydrophobicContact CD2-CE2 4.49Å; L273-F285 HydrophobicContact CD2-CG 3.57Å; L273-F285 HydrophobicContact CG-CB 4.22Å; L273-F285 HydrophobicContact CG-CG 4.48Å; D281-F285 WeakPolarHBondContact O-CB 3.41Å; D281-F285 PolarHBondContact O-N 3.49Å; S282-F285 PolarHBondContact O-N 2.86Å; L283-F285 VanDerWaalsContact C-N 3.3Å; L283-F285 PolarHBondContact O-N 3.18Å; F285-V287 PolarHBondContact O-N 3.46Å; F285-L288 PolarHBondContact O-N 3.15Å; F285-M289 HydrophobicContact CD1-CG 4.12Å; F285-M289 HydrophobicContact CD2-CG 4.32Å; F285-M289 HydrophobicContact CE1-CG 3.7Å; F285-M289 HydrophobicContact CE2-CE 4.13Å; F285-M289 HydrophobicContact CE2-CG 3.92Å; F285-M289 HydrophobicContact CE2-SD 4.3Å; F285-M289 HydrophobicContact CG-CG 4.41Å; F285-M289 HydrophobicContact CZ-CE 4.38Å; F285-M289 HydrophobicContact CZ-CG 3.59Å; F285-M289 HydrophobicContact CZ-SD 3.97Å; F285-M289 WeakPolarHBondContact O-CB 3.47Å; F285-M289 WeakPolarHBondContact O-CG 3.43Å; F285-M289 PolarHBondContact O-N 2.98Å
286	A	93.1	Very high	91.4	Very high	52 Å²	52	88.9 Å²	88.9	43%	0.43	47%	0.467	S	S	.	.	H	α-helix	trans	-62.1	-43.2	176.3	0	0	0	0	0	112.1	S282 L283 M289 W290	S282-A286 WeakPolarHBondContact O-CB 3.2Å; S282-A286 PolarHBondContact O-N 3.46Å; L283-A286 PolarHBondContact O-N 3.23Å; A286-M289 PolarHBondContact O-N 2.9Å; A286-W290 WeakPolarHBondContact O-CB 3.35Å; A286-W290 PolarHBondContact O-N 3.24Å
287	V	95.4	Very high	91.4	Very high	77 Å²	77	89.7 Å²	89.7	47%	0.467	48%	0.481	S	S	.	.	H	α-helix	trans	-64.7	-43.1	174.8	173.8	0	0	0	0	111.1	L283 F285 W290 V291	L283-V287 HydrophobicContact CD1-CG2 4.47Å; L283-V287 WeakPolarHBondContact O-CG2 3.45Å; L283-V287 PolarHBondContact O-N 2.82Å; F285-V287 PolarHBondContact O-N 3.46Å; V287-W290 PolarHBondContact O-N 2.74Å; V287-V291 WeakPolarHBondContact O-CG2 3.37Å; V287-V291 PolarHBondContact O-N 3.41Å
288	L	94.5	Very high	91.1	Very high	101 Å²	101	88.5 Å²	88.5	53%	0.529	48%	0.475	S	S	.	.	H	α-helix	trans	-59.5	-48	174.9	-172.1	165.2	0	0	0	110.5	K284 F285 W290 V291 F292	K284-L288 VanDerWaalsContact O-CB 3.31Å; K284-L288 WeakPolarHBondContact O-CB 3.01Å; K284-L288 PolarHBondContact O-N 3.1Å; F285-L288 PolarHBondContact O-N 3.15Å; L288-W290 VanDerWaalsContact C-N 3.32Å; L288-W290 PolarHBondContact O-N 3.44Å; L288-V291 PolarHBondContact O-N 2.94Å; L288-F292 WeakPolarHBondContact O-CB 3.41Å; L288-F292 PolarHBondContact O-N 3.49Å
289	M	93.8	Very high	91	Very high	68 Å²	68	90 Å²	90	34%	0.335	48%	0.478	S	S	.	.	H	α-helix	trans	-62	-37.5	176.2	-76.3	-67.4	103.2	0	0	112.1	F285 A286 F292 T293	F285-M289 HydrophobicContact CD1-CG 4.12Å; F285-M289 HydrophobicContact CD2-CG 4.32Å; F285-M289 HydrophobicContact CE1-CG 3.7Å; F285-M289 HydrophobicContact CE2-CE 4.13Å; F285-M289 HydrophobicContact CE2-CG 3.92Å; F285-M289 HydrophobicContact CE2-SD 4.3Å; F285-M289 HydrophobicContact CG-CG 4.41Å; F285-M289 HydrophobicContact CZ-CE 4.38Å; F285-M289 HydrophobicContact CZ-CG 3.59Å; F285-M289 HydrophobicContact CZ-SD 3.97Å; F285-M289 WeakPolarHBondContact O-CB 3.47Å; F285-M289 WeakPolarHBondContact O-CG 3.43Å; F285-M289 PolarHBondContact O-N 2.98Å; A286-M289 PolarHBondContact O-N 2.9Å; M289-F292 HydrophobicContact CE-CB 4.18Å; M289-F292 HydrophobicContact CE-CD1 4.36Å; M289-F292 HydrophobicContact CE-CG 4.24Å; M289-F292 CarbonylContact O-C 3.52Å; M289-F292 WeakPolarHBondContact O-CA 3.33Å; M289-F292 WeakPolarHBondContact O-CB 3.48Å; M289-F292 PolarHBondContact O-N 2.81Å; M289-F292 VanDerWaalsContact O-N 3.16Å; M289-T293 WeakPolarHBondContact O-CG2 3.04Å; M289-T293 PolarHBondContact O-N 2.97Å
290	W	93.8	Very high	90.8	Very high	184 Å²	184	88.3 Å²	88.3	70%	0.697	47%	0.47	S	S	*	.	H	α-helix	trans	-65.7	-40.3	175	177.8	69.5	0	0	0	112.8	A286 V287 L288 F292 T293 Y294	A286-W290 WeakPolarHBondContact O-CB 3.35Å; A286-W290 PolarHBondContact O-N 3.24Å; V287-W290 PolarHBondContact O-N 2.74Å; L288-W290 VanDerWaalsContact C-N 3.32Å; L288-W290 PolarHBondContact O-N 3.44Å; W290-F292 VanDerWaalsContact C-N 3.29Å; W290-T293 PolarHBondContact O-OG1 3.09Å; W290-Y294 PolarHBondContact O-N 3.13Å
291	V	94.6	Very high	90.4	Very high	75 Å²	75	86.4 Å²	86.4	46%	0.455	47%	0.469	S	S	.	.	H	α-helix	trans	-65	-39.2	170.6	175.9	0	0	0	0	110.1	V287 L288 Y294 V295	V287-V291 WeakPolarHBondContact O-CG2 3.37Å; V287-V291 PolarHBondContact O-N 3.41Å; L288-V291 PolarHBondContact O-N 2.94Å; V291-Y294 WeakPolarHBondContact O-CB 3.15Å; V291-Y294 PolarHBondContact O-N 3.38Å; V291-V295 HydrophobicContact CG1-CG2 4.49Å; V291-V295 WeakPolarHBondContact O-CG2 3.38Å; V291-V295 PolarHBondContact O-N 2.73Å
292	F	90.1	Very high	90.3	Very high	126 Å²	126	85.8 Å²	85.8	55%	0.553	47%	0.465	S	S	*	.	H	α-helix	trans	-65.6	-39.1	178.4	-171.9	-97.8	0	0	0	112.8	L288 M289 W290 Y294 V295 G296	L288-F292 WeakPolarHBondContact O-CB 3.41Å; L288-F292 PolarHBondContact O-N 3.49Å; M289-F292 HydrophobicContact CE-CB 4.18Å; M289-F292 HydrophobicContact CE-CD1 4.36Å; M289-F292 HydrophobicContact CE-CG 4.24Å; M289-F292 CarbonylContact O-C 3.52Å; M289-F292 WeakPolarHBondContact O-CA 3.33Å; M289-F292 WeakPolarHBondContact O-CB 3.48Å; M289-F292 PolarHBondContact O-N 2.81Å; M289-F292 VanDerWaalsContact O-N 3.16Å; W290-F292 VanDerWaalsContact C-N 3.29Å; F292-Y294 VanDerWaalsContact C-N 3.27Å; F292-Y294 PolarHBondContact O-N 3.46Å; F292-V295 PolarHBondContact O-N 3.28Å; F292-G296 PolarHBondContact O-N 3.48Å
293	T	90.9	Very high	90.1	Very high	90 Å²	90	87.4 Å²	87.4	55%	0.552	48%	0.475	S	S	*	.	H	α-helix	trans	-62.6	-37.8	174.1	58.7	0	0	0	0	111	M289 W290 G296 A297	M289-T293 WeakPolarHBondContact O-CG2 3.04Å; M289-T293 PolarHBondContact O-N 2.97Å; W290-T293 PolarHBondContact O-OG1 3.09Å; T293-G296 PolarHBondContact O-N 2.84Å; T293-A297 WeakPolarHBondContact O-CB 3.36Å; T293-A297 PolarHBondContact O-N 2.84Å
294	Y	89	Confident	90	Very high	155 Å²	155	85.1 Å²	85.1	61%	0.608	46%	0.463	S	S	*	.	H	α-helix	trans	-64.9	-46.5	173.6	-172.1	-106.4	0	0	0	111.9	W290 V291 F292 G296 A297 L298	W290-Y294 PolarHBondContact O-N 3.13Å; V291-Y294 WeakPolarHBondContact O-CB 3.15Å; V291-Y294 PolarHBondContact O-N 3.38Å; F292-Y294 VanDerWaalsContact C-N 3.27Å; F292-Y294 PolarHBondContact O-N 3.46Å; Y294-G296 VanDerWaalsContact C-N 3.32Å; Y294-G296 PolarHBondContact O-N 2.78Å; Y294-A297 WeakPolarHBondContact O-CB 3.44Å; Y294-A297 PolarHBondContact O-N 2.89Å; Y294-A297 VanDerWaalsContact O-N 3.15Å; Y294-L298 HydrophobicContact CD1-CD1 3.94Å; Y294-L298 HydrophobicContact CD1-CG 4.4Å; Y294-L298 HydrophobicContact CE1-CD1 3.54Å; Y294-L298 HydrophobicContact CE1-CD2 4.46Å; Y294-L298 HydrophobicContact CE1-CG 4.13Å; Y294-L298 WeakPolarHBondContact O-CG 3.25Å; Y294-L298 PolarHBondContact O-N 3.16Å; Y294-L298 VanDerWaalsContact O-N 3.1Å
295	V	87.5	Confident	89.9	Confident	52 Å²	52	82.9 Å²	82.9	32%	0.315	46%	0.457	S	S	.	.	H	α-helix	trans	-60.7	-41.7	176.2	175.5	0	0	0	0	111.5	V291 F292 A297 L298 F299	V291-V295 HydrophobicContact CG1-CG2 4.49Å; V291-V295 WeakPolarHBondContact O-CG2 3.38Å; V291-V295 PolarHBondContact O-N 2.73Å; F292-V295 PolarHBondContact O-N 3.28Å; V295-A297 VanDerWaalsContact C-N 3.31Å; V295-A297 PolarHBondContact O-N 3.38Å; V295-L298 PolarHBondContact O-N 3.39Å; V295-F299 HydrophobicContact CG1-CD2 4.22Å; V295-F299 WeakPolarHBondContact O-CD2 3.39Å; V295-F299 PolarHBondContact O-N 2.91Å
296	G	86.6	Confident	89.9	Confident	43 Å²	43	81 Å²	81	44%	0.443	45%	0.449	S	S	.	.	H	α-helix	trans	-65.8	-31	175.7	0	0	0	0	0	113.6	F292 T293 Y294 L298	F292-G296 PolarHBondContact O-N 3.48Å; T293-G296 PolarHBondContact O-N 2.84Å; Y294-G296 VanDerWaalsContact C-N 3.32Å; Y294-G296 PolarHBondContact O-N 2.78Å; G296-L298 VanDerWaalsContact C-N 3.33Å
297	A	87.9	Confident	89.9	Confident	85 Å²	85	82 Å²	82	70%	0.702	45%	0.447	S	S	*	.	H	α-helix	trans	-72.4	-26.3	173.2	0	0	0	0	0	112.8	T293 Y294 V295	T293-A297 WeakPolarHBondContact O-CB 3.36Å; T293-A297 PolarHBondContact O-N 2.84Å; Y294-A297 WeakPolarHBondContact O-CB 3.44Å; Y294-A297 PolarHBondContact O-N 2.89Å; Y294-A297 VanDerWaalsContact O-N 3.15Å; V295-A297 VanDerWaalsContact C-N 3.31Å; V295-A297 PolarHBondContact O-N 3.38Å
298	L	82.5	Confident	89.8	Confident	96 Å²	96	81.1 Å²	81.1	50%	0.503	45%	0.448	S	S	.	.	H	α-helix	trans	-82.1	-30.2	180	-68.3	-178.9	0	0	0	113.5	Y294 V295 G296	Y294-L298 HydrophobicContact CD1-CD1 3.94Å; Y294-L298 HydrophobicContact CD1-CG 4.4Å; Y294-L298 HydrophobicContact CE1-CD1 3.54Å; Y294-L298 HydrophobicContact CE1-CD2 4.46Å; Y294-L298 HydrophobicContact CE1-CG 4.13Å; Y294-L298 WeakPolarHBondContact O-CG 3.25Å; Y294-L298 PolarHBondContact O-N 3.16Å; Y294-L298 VanDerWaalsContact O-N 3.1Å; V295-L298 PolarHBondContact O-N 3.39Å; G296-L298 VanDerWaalsContact C-N 3.33Å
299	F	87.5	Confident	89.7	Confident	83 Å²	83	77.6 Å²	77.6	36%	0.364	43%	0.429	S	S	.	.	S	Bend	trans	-130.2	128.3	-171.4	-59.8	-79.4	0	0	0	112	V295 G301 T303 L304 L307	V295-F299 HydrophobicContact CG1-CD2 4.22Å; V295-F299 WeakPolarHBondContact O-CD2 3.39Å; V295-F299 PolarHBondContact O-N 2.91Å; F299-G301 PolarHBondContact O-N 2.96Å; F299-T303 HydrophobicContact CD1-CG2 4.36Å; F299-L304 HydrophobicContact CB-CD1 4.1Å; F299-L304 HydrophobicContact CB-CD2 3.47Å; F299-L304 VanDerWaalsContact CB-CD2 3.47Å; F299-L304 HydrophobicContact CB-CG 3.48Å; F299-L304 VanDerWaalsContact CB-CG 3.48Å; F299-L304 HydrophobicContact CD1-CD2 4.14Å; F299-L304 HydrophobicContact CD2-CD2 3.68Å; F299-L304 HydrophobicContact CE2-CD2 4.44Å; F299-L304 HydrophobicContact CG-CD2 3.5Å; F299-L304 HydrophobicContact CG-CG 4.12Å; F299-L307 HydrophobicContact CD1-CD1 4.32Å; F299-L307 HydrophobicContact CE1-CD1 4.16Å
300	N	86.4	Confident	89.7	Confident	96 Å²	96	77.1 Å²	77.1	51%	0.513	43%	0.427	S	S	.	.			trans	-55.5	133.9	163.4	-179.1	-1.5	0	0	0	108.5	L302 T303 L304	N300-L302 PolarHBondContact O-N 3.25Å; N300-L302 VanDerWaalsContact O-N 3.08Å; N300-L302 PolarHBondContact OD1-N 2.77Å; N300-T303 WeakPolarHBondContact O-CA 3.44Å; N300-T303 VanDerWaalsContact O-CB 3.29Å; N300-T303 WeakPolarHBondContact O-CB 3.28Å; N300-T303 PolarHBondContact O-N 3.27Å; N300-L304 PolarHBondContact O-N 2.94Å
301	G	85	Confident	89.6	Confident	51 Å²	51	70.7 Å²	70.7	53%	0.526	41%	0.411	S	S	.	.	H	α-helix	trans	-53.8	-33.4	-177.9	0	0	0	0	0	112.6	F299 L304 L305	F299-G301 PolarHBondContact O-N 2.96Å; G301-L304 PolarHBondContact O-N 3.01Å; G301-L305 PolarHBondContact O-N 3.2Å
302	L	87.7	Confident	89.5	Confident	35 Å²	35	71.7 Å²	71.7	18%	0.183	41%	0.413	C	S	.	.	H	α-helix	trans	-69.3	-37.9	172.5	-73	168.2	0	0	0	113.5	L195 T196 N300 L304 L305 I306	L195-L302 HydrophobicContact CB-CD1 4.5Å; L195-L302 HydrophobicContact CB-CD2 3.96Å; L195-L302 HydrophobicContact CD2-CD2 4.27Å; L195-L302 WeakPolarHBondContact O-CD1 3.17Å; T196-L302 HydrophobicContact CG2-CB 3.76Å; T196-L302 HydrophobicContact CG2-CD1 4.27Å; N300-L302 PolarHBondContact O-N 3.25Å; N300-L302 VanDerWaalsContact O-N 3.08Å; N300-L302 PolarHBondContact OD1-N 2.77Å; L302-L304 VanDerWaalsContact C-N 3.33Å; L302-L304 PolarHBondContact O-N 3.42Å; L302-L305 WeakPolarHBondContact O-CB 3.48Å; L302-L305 PolarHBondContact O-N 3.25Å; L302-L305 VanDerWaalsContact O-N 3.17Å; L302-I306 WeakPolarHBondContact O-CG1 3.47Å; L302-I306 PolarHBondContact O-N 3.05Å
303	T	88.4	Confident	89.5	Confident	55 Å²	55	66.4 Å²	66.4	34%	0.337	39%	0.39	S	S	.	.	H	α-helix	trans	-62.2	-41.7	173	-57.5	0	0	0	0	111	F299 N300 L305 I306 L307	F299-T303 HydrophobicContact CD1-CG2 4.36Å; N300-T303 WeakPolarHBondContact O-CA 3.44Å; N300-T303 VanDerWaalsContact O-CB 3.29Å; N300-T303 WeakPolarHBondContact O-CB 3.28Å; N300-T303 PolarHBondContact O-N 3.27Å; T303-L305 VanDerWaalsContact C-N 3.3Å; T303-L305 PolarHBondContact O-N 2.83Å; T303-I306 PolarHBondContact O-N 2.79Å; T303-L307 HydrophobicContact CG2-CD1 4.34Å; T303-L307 WeakPolarHBondContact O-CB 3.46Å; T303-L307 WeakPolarHBondContact O-CG 3.24Å; T303-L307 PolarHBondContact O-N 3.47Å
304	L	90.4	Very high	89.4	Confident	65 Å²	65	63.9 Å²	63.9	34%	0.34	38%	0.376	S	S	.	.	H	α-helix	trans	-61.3	-40.3	173.1	-70.9	-176.9	0	0	0	111.8	F299 N300 G301 L302 L307 A308	F299-L304 HydrophobicContact CB-CD1 4.1Å; F299-L304 HydrophobicContact CB-CD2 3.47Å; F299-L304 VanDerWaalsContact CB-CD2 3.47Å; F299-L304 HydrophobicContact CB-CG 3.48Å; F299-L304 VanDerWaalsContact CB-CG 3.48Å; F299-L304 HydrophobicContact CD1-CD2 4.14Å; F299-L304 HydrophobicContact CD2-CD2 3.68Å; F299-L304 HydrophobicContact CE2-CD2 4.44Å; F299-L304 HydrophobicContact CG-CD2 3.5Å; F299-L304 HydrophobicContact CG-CG 4.12Å; N300-L304 PolarHBondContact O-N 2.94Å; G301-L304 PolarHBondContact O-N 3.01Å; L302-L304 VanDerWaalsContact C-N 3.33Å; L302-L304 PolarHBondContact O-N 3.42Å; L304-L307 PolarHBondContact O-N 3.3Å; L304-A308 VanDerWaalsContact O-CB 3.31Å; L304-A308 WeakPolarHBondContact O-CB 3.35Å; L304-A308 PolarHBondContact O-N 3.49Å
305	L	90.7	Very high	89.5	Confident	87 Å²	87	61.6 Å²	61.6	46%	0.455	37%	0.373	S	S	.	.	H	α-helix	trans	-64.8	-41	177.2	-172.8	57.8	0	0	0	111.9	L192 G301 L302 T303 A308 L309	L192-L305 HydrophobicContact CD1-CG 4.08Å; L192-L305 HydrophobicContact CD2-CD2 3.39Å; L192-L305 HydrophobicContact CD2-CG 3.7Å; G301-L305 PolarHBondContact O-N 3.2Å; L302-L305 WeakPolarHBondContact O-CB 3.48Å; L302-L305 PolarHBondContact O-N 3.25Å; L302-L305 VanDerWaalsContact O-N 3.17Å; T303-L305 VanDerWaalsContact C-N 3.3Å; T303-L305 PolarHBondContact O-N 2.83Å; L305-A308 PolarHBondContact O-N 3.25Å; L305-L309 PolarHBondContact O-N 3.03Å
306	I	92.4	Very high	89.6	Confident	24 Å²	24	59.9 Å²	59.9	12%	0.123	36%	0.363	C	S	.	.	H	α-helix	trans	-61.9	-48.6	173	-71.5	168	0	0	0	110.7	L189 L192 T196 L302 T303 A308 L309 I310	L189-I306 HydrophobicContact CD1-CG2 3.76Å; L192-I306 HydrophobicContact CB-CD1 4.31Å; L192-I306 HydrophobicContact CB-CG1 3.66Å; L192-I306 HydrophobicContact CD1-CG1 4.05Å; L192-I306 HydrophobicContact CG-CG1 4.48Å; T196-I306 HydrophobicContact CG2-CD1 3.46Å; T196-I306 VanDerWaalsContact CG2-CD1 3.46Å; L302-I306 WeakPolarHBondContact O-CG1 3.47Å; L302-I306 PolarHBondContact O-N 3.05Å; T303-I306 PolarHBondContact O-N 2.79Å; I306-A308 VanDerWaalsContact C-N 3.29Å; I306-A308 PolarHBondContact O-N 2.85Å; I306-L309 PolarHBondContact O-N 3.25Å; I306-I310 HydrophobicContact CG2-CD1 3.62Å; I306-I310 HydrophobicContact CG2-CG1 4.26Å; I306-I310 VanDerWaalsContact O-CG1 3.29Å; I306-I310 WeakPolarHBondContact O-CG1 3.35Å; I306-I310 PolarHBondContact O-N 3.47Å
307	L	92.8	Very high	89.7	Confident	75 Å²	75	60.3 Å²	60.3	39%	0.393	36%	0.357	S	S	.	.	H	α-helix	trans	-61.9	-38.4	178.2	-71.8	177	0	0	0	111.8	F299 T303 L304 I310 S311	F299-L307 HydrophobicContact CD1-CD1 4.32Å; F299-L307 HydrophobicContact CE1-CD1 4.16Å; T303-L307 HydrophobicContact CG2-CD1 4.34Å; T303-L307 WeakPolarHBondContact O-CB 3.46Å; T303-L307 WeakPolarHBondContact O-CG 3.24Å; T303-L307 PolarHBondContact O-N 3.47Å; L304-L307 PolarHBondContact O-N 3.3Å; L307-I310 PolarHBondContact O-N 2.81Å; L307-S311 WeakPolarHBondContact O-CB 3.25Å; L307-S311 PolarHBondContact O-N 3.2Å; L307-S311 PolarHBondContact O-OG 3.25Å
308	A	93	Very high	89.7	Confident	57 Å²	57	60.5 Å²	60.5	47%	0.471	35%	0.345	S	S	.	.	H	α-helix	trans	-64.1	-44.1	175.2	0	0	0	0	0	111.4	L304 L305 I306 S311 L312	L304-A308 VanDerWaalsContact O-CB 3.31Å; L304-A308 WeakPolarHBondContact O-CB 3.35Å; L304-A308 PolarHBondContact O-N 3.49Å; L305-A308 PolarHBondContact O-N 3.25Å; I306-A308 VanDerWaalsContact C-N 3.29Å; I306-A308 PolarHBondContact O-N 2.85Å; A308-S311 PolarHBondContact O-N 3.45Å; A308-L312 VanDerWaalsContact O-CB 3.27Å; A308-L312 WeakPolarHBondContact O-CB 3.44Å; A308-L312 PolarHBondContact O-N 2.92Å
309	L	93.7	Very high	90.1	Very high	27 Å²	27	59.7 Å²	59.7	14%	0.141	34%	0.336	C	S	.	.	H	α-helix	trans	-62.1	-49	175.3	-177.7	72.8	0	0	0	111.4	S188 L189 L192 L305 I306 S311 L312 F313	S188-L309 WeakPolarHBondContact OG-CD2 3.21Å; L189-L309 HydrophobicContact CB-CD2 4.31Å; L192-L309 HydrophobicContact CD1-CB 3.86Å; L192-L309 HydrophobicContact CD1-CD2 3.51Å; L192-L309 HydrophobicContact CD1-CG 4.26Å; L192-L309 HydrophobicContact CG-CD2 4.43Å; L305-L309 PolarHBondContact O-N 3.03Å; I306-L309 PolarHBondContact O-N 3.25Å; L309-S311 VanDerWaalsContact C-N 3.3Å; L309-S311 PolarHBondContact O-N 2.8Å; L309-L312 WeakPolarHBondContact O-CB 3.34Å; L309-L312 PolarHBondContact O-N 3.43Å; L309-F313 HydrophobicContact CD1-CD2 4.16Å; L309-F313 HydrophobicContact CD1-CE2 3.85Å; L309-F313 WeakPolarHBondContact O-CD2 3.34Å; L309-F313 PolarHBondContact O-N 3.39Å
310	I	93.4	Very high	90.1	Very high	58 Å²	58	61.6 Å²	61.6	30%	0.297	35%	0.346	S	S	.	.	H	α-helix	trans	-58.3	-46.7	176.9	-66.5	169.9	0	0	0	109.8	F185 L189 I306 L307 L312 F313 S314	F185-I310 HydrophobicContact CE2-CG1 4.23Å; F185-I310 HydrophobicContact CZ-CG1 4.1Å; L189-I310 HydrophobicContact CD1-CD1 4.36Å; L189-I310 HydrophobicContact CD1-CG1 4.32Å; I306-I310 HydrophobicContact CG2-CD1 3.62Å; I306-I310 HydrophobicContact CG2-CG1 4.26Å; I306-I310 VanDerWaalsContact O-CG1 3.29Å; I306-I310 WeakPolarHBondContact O-CG1 3.35Å; I306-I310 PolarHBondContact O-N 3.47Å; L307-I310 PolarHBondContact O-N 2.81Å; I310-L312 VanDerWaalsContact C-N 3.34Å; I310-L312 PolarHBondContact O-N 2.83Å; I310-F313 PolarHBondContact O-N 2.87Å; I310-S314 WeakPolarHBondContact O-CA 3.35Å; I310-S314 WeakPolarHBondContact O-CB 3.34Å; I310-S314 PolarHBondContact O-N 3.44Å; I310-S314 PolarHBondContact O-OG 2.81Å
311	S	92	Very high	90.2	Very high	50 Å²	50	66.9 Å²	66.9	35%	0.35	36%	0.359	S	S	.	.	H	α-helix	trans	-62.7	-40.3	178.6	-61.6	0	0	0	0	111.8	L307 A308 L309 F313 S314 I315	L307-S311 WeakPolarHBondContact O-CB 3.25Å; L307-S311 PolarHBondContact O-N 3.2Å; L307-S311 PolarHBondContact O-OG 3.25Å; A308-S311 PolarHBondContact O-N 3.45Å; L309-S311 VanDerWaalsContact C-N 3.3Å; L309-S311 PolarHBondContact O-N 2.8Å; S311-F313 VanDerWaalsContact C-N 3.28Å; S311-F313 PolarHBondContact O-N 2.81Å; S311-S314 PolarHBondContact O-N 3.25Å; S311-I315 WeakPolarHBondContact O-CB 3.27Å; S311-I315 WeakPolarHBondContact O-CG1 3.31Å; S311-I315 PolarHBondContact O-N 3.38Å
312	L	91.9	Very high	90.5	Very high	96 Å²	96	68 Å²	68	50%	0.503	35%	0.35	S	S	.	.	H	α-helix	trans	-59.5	-39.3	179.5	-175.4	64.5	0	0	0	111.9	L173 A308 L309 I310 P316	L173-L312 HydrophobicContact CD1-CD1 4.43Å; L173-L312 HydrophobicContact CD1-CD2 4.44Å; L173-L312 HydrophobicContact CD1-CG 3.89Å; L173-L312 HydrophobicContact CD2-CD1 4.11Å; L173-L312 HydrophobicContact CD2-CG 4.41Å; L173-L312 WeakPolarHBondContact CD2-O 3.35Å; L173-L312 VanDerWaalsContact CG-O 3.27Å; L173-L312 WeakPolarHBondContact CG-O 3.33Å; A308-L312 VanDerWaalsContact O-CB 3.27Å; A308-L312 WeakPolarHBondContact O-CB 3.44Å; A308-L312 PolarHBondContact O-N 2.92Å; L309-L312 WeakPolarHBondContact O-CB 3.34Å; L309-L312 PolarHBondContact O-N 3.43Å; I310-L312 VanDerWaalsContact C-N 3.34Å; I310-L312 PolarHBondContact O-N 2.83Å; L312-P316 WeakPolarHBondContact O-CD 3.33Å; L312-P316 WeakPolarHBondContact O-CG 2.98Å
313	F	90.5	Very high	90.6	Very high	14 Å²	14	70.9 Å²	70.9	6%	0.061	36%	0.363	C	S	.	.	H	α-helix	trans	-89.2	-25.9	176.7	-76.8	-88.5	0	0	0	114.1	L173 V184 F185 L309 I310 S311	L173-F313 HydrophobicContact CD1-CD1 4.04Å; L173-F313 HydrophobicContact CD1-CD2 4.48Å; L173-F313 HydrophobicContact CD1-CE1 3.97Å; L173-F313 HydrophobicContact CD1-CE2 4.41Å; L173-F313 HydrophobicContact CD1-CG 4.31Å; L173-F313 HydrophobicContact CD1-CZ 4.16Å; V184-F313 HydrophobicContact CG1-CZ 4.43Å; F185-F313 HydrophobicContact CD2-CB 3.98Å; F185-F313 AromaticContact CD2-CD2 3.72Å; F185-F313 HydrophobicContact CD2-CD2 3.72Å; F185-F313 HydrophobicContact CD2-CE2 4.35Å; F185-F313 AromaticContact CD2-CG 3.84Å; F185-F313 HydrophobicContact CD2-CG 3.84Å; F185-F313 HydrophobicContact CE2-CB 4.27Å; F185-F313 HydrophobicContact CE2-CD2 4.4Å; L309-F313 HydrophobicContact CD1-CD2 4.16Å; L309-F313 HydrophobicContact CD1-CE2 3.85Å; L309-F313 WeakPolarHBondContact O-CD2 3.34Å; L309-F313 PolarHBondContact O-N 3.39Å; I310-F313 PolarHBondContact O-N 2.87Å; S311-F313 VanDerWaalsContact C-N 3.28Å; S311-F313 PolarHBondContact O-N 2.81Å
314	S	89	Confident	90.7	Very high	37 Å²	37	72.2 Å²	72.2	26%	0.259	38%	0.38	S	S	.	.	H	α-helix	trans	-88.8	-39.5	-175.4	-56.6	0	0	0	0	112.4	I310 S311 V317 I318	I310-S314 WeakPolarHBondContact O-CA 3.35Å; I310-S314 WeakPolarHBondContact O-CB 3.34Å; I310-S314 PolarHBondContact O-N 3.44Å; I310-S314 PolarHBondContact O-OG 2.81Å; S311-S314 PolarHBondContact O-N 3.25Å; S314-V317 PolarHBondContact O-N 3.28Å; S314-I318 WeakPolarHBondContact O-CB 3.5Å; S314-I318 WeakPolarHBondContact O-CD1 3.28Å; S314-I318 WeakPolarHBondContact O-CG1 3.31Å; S314-I318 PolarHBondContact O-N 3.4Å
315	I	91	Very high	90.8	Very high	107 Å²	107	74.5 Å²	74.5	55%	0.549	39%	0.388	S	S	.	.	H	α-helix	trans	-55.7	-49.2	-178.5	-71.2	169.5	0	0	0	111.5	S311 V317 I318 Y319	S311-I315 WeakPolarHBondContact O-CB 3.27Å; S311-I315 WeakPolarHBondContact O-CG1 3.31Å; S311-I315 PolarHBondContact O-N 3.38Å; I315-V317 VanDerWaalsContact C-N 3.35Å; I315-V317 PolarHBondContact O-N 2.92Å; I315-I318 PolarHBondContact O-N 2.93Å; I315-Y319 WeakPolarHBondContact O-CB 3.46Å; I315-Y319 PolarHBondContact O-N 3.37Å
316	P	88.4	Confident	90.9	Very high	17 Å²	17	73 Å²	73	11%	0.11	38%	0.38	C	S	.	.	H	α-helix	trans	-61.2	-42.1	-179.5	-23.1	34.6	0	0	0	112.8	L173 Y174 L312 Y319 E320	L173-P316 HydrophobicContact CB-CG 4.46Å; L173-P316 HydrophobicContact CD2-CG 3.78Å; L173-P316 HydrophobicContact CG-CG 3.97Å; Y174-P316 HydrophobicContact CD1-CB 4.38Å; Y174-P316 HydrophobicContact CD2-CB 4.28Å; Y174-P316 HydrophobicContact CE1-CB 4.21Å; Y174-P316 HydrophobicContact CE2-CB 4.11Å; Y174-P316 HydrophobicContact CG-CB 4.43Å; L312-P316 WeakPolarHBondContact O-CD 3.33Å; L312-P316 WeakPolarHBondContact O-CG 2.98Å; P316-Y319 PolarHBondContact O-N 2.78Å; P316-E320 PolarHBondContact O-N 3.26Å
317	V	88.5	Confident	91	Very high	51 Å²	51	74.9 Å²	74.9	31%	0.309	39%	0.39	S	S	.	.	H	α-helix	trans	-69.9	-44.9	-179.4	178.2	0	0	0	0	111.8	W175 S314 I315 Y319 E320 R321	W175-V317 HydrophobicContact CB-CG2 4.35Å; W175-V317 HydrophobicContact CG-CG2 4.06Å; S314-V317 PolarHBondContact O-N 3.28Å; I315-V317 VanDerWaalsContact C-N 3.35Å; I315-V317 PolarHBondContact O-N 2.92Å; V317-Y319 VanDerWaalsContact C-N 3.26Å; V317-Y319 PolarHBondContact O-N 2.96Å; V317-E320 PolarHBondContact O-N 3.06Å; V317-R321 WeakPolarHBondContact O-CB 3.25Å; V317-R321 PolarHBondContact O-N 3.49Å
318	I	89.5	Confident	91	Very high	89 Å²	89	77.3 Å²	77.3	46%	0.456	40%	0.399	S	S	.	.	H	α-helix	trans	-63.2	-39	176.2	-67.6	165	0	0	0	109.6	S314 I315 R321 H322 I326	S314-I318 WeakPolarHBondContact O-CB 3.5Å; S314-I318 WeakPolarHBondContact O-CD1 3.28Å; S314-I318 WeakPolarHBondContact O-CG1 3.31Å; S314-I318 PolarHBondContact O-N 3.4Å; I315-I318 PolarHBondContact O-N 2.93Å; I318-R321 PolarHBondContact O-N 2.8Å; I318-H322 WeakPolarHBondContact O-CB 3.27Å; I318-H322 PolarHBondContact O-N 3.47Å; I318-I326 HydrophobicContact CG2-CD1 4.14Å
319	Y	89.7	Confident	91	Very high	80 Å²	80	82.1 Å²	82.1	31%	0.314	41%	0.407	S	S	.	.	H	α-helix	trans	-62.3	-49.5	175.7	-172.9	-100.8	0	0	0	111.8	I315 P316 V317 R321 H322 Q323 I326 D327	I315-Y319 WeakPolarHBondContact O-CB 3.46Å; I315-Y319 PolarHBondContact O-N 3.37Å; P316-Y319 PolarHBondContact O-N 2.78Å; V317-Y319 VanDerWaalsContact C-N 3.26Å; V317-Y319 PolarHBondContact O-N 2.96Å; Y319-R321 VanDerWaalsContact C-N 3.27Å; Y319-R321 PolarHBondContact O-N 3.46Å; Y319-H322 PolarHBondContact O-N 3.37Å; Y319-Q323 HydrophobicContact CE1-CG 3.91Å; Y319-Q323 HydrophobicContact CE2-CG 4.27Å; Y319-Q323 WeakPolarHBondContact O-CA 3.46Å; Y319-Q323 VanDerWaalsContact O-CB 3.25Å; Y319-Q323 WeakPolarHBondContact O-CB 3.42Å; Y319-Q323 PolarHBondContact O-N 2.87Å; Y319-Q323 PolarHBondContact OH-NE2 3.15Å; Y319-I326 HydrophobicContact CD2-CB 4.5Å; Y319-I326 HydrophobicContact CD2-CD1 4.25Å; Y319-I326 HydrophobicContact CD2-CG2 4.1Å; Y319-I326 HydrophobicContact CE2-CG2 4.21Å; Y319-D327 WeakPolarHBondContact CE2-OD1 3.31Å; Y319-D327 PolarHBondContact OH-OD1 2.99Å; Y319-D327 PolarHBondContact OH-OD2 3.45Å
320	E	87.3	Confident	91	Very high	123 Å²	123	85.3 Å²	85.3	58%	0.575	42%	0.423	S	S	*	.	H	α-helix	trans	-59.9	-38.1	177.8	-170.7	176	-175	0	0	112	P316 V317	P316-E320 PolarHBondContact O-N 3.26Å; V317-E320 PolarHBondContact O-N 3.06Å
321	R	89.2	Confident	91.1	Very high	206 Å²	206	84.4 Å²	84.4	78%	0.777	43%	0.429	S	S	*	.	H	α-helix	trans	-76.6	-33.1	-178.3	-167.4	172.1	-169	169.3	2.2	114	V317 I318 Y319	V317-R321 WeakPolarHBondContact O-CB 3.25Å; V317-R321 PolarHBondContact O-N 3.49Å; I318-R321 PolarHBondContact O-N 2.8Å; Y319-R321 VanDerWaalsContact C-N 3.27Å; Y319-R321 PolarHBondContact O-N 3.46Å
322	H	90.9	Very high	91.2	Very high	76 Å²	76	86.4 Å²	86.4	35%	0.352	44%	0.435	S	S	.	.	H	α-helix	trans	-121.6	22.4	-172.9	-66.1	-80.8	0	0	0	113.4	I318 Y319 A324 Q325 I326	I318-H322 WeakPolarHBondContact O-CB 3.27Å; I318-H322 PolarHBondContact O-N 3.47Å; Y319-H322 PolarHBondContact O-N 3.37Å; H322-A324 VanDerWaalsContact C-N 3.35Å; H322-A324 PolarHBondContact O-N 3.45Å; H322-Q325 PolarHBondContact ND1-OE1 2.79Å; H322-Q325 PolarHBondContact O-N 2.95Å; H322-I326 HydrophobicContact CB-CD1 3.79Å; H322-I326 HydrophobicContact CB-CG1 4.11Å; H322-I326 WeakPolarHBondContact O-CG1 3.5Å; H322-I326 PolarHBondContact O-N 3.45Å
323	Q	89.1	Confident	91.4	Very high	94 Å²	94	84.2 Å²	84.2	44%	0.439	43%	0.43	S	S	.	.	H	α-helix	trans	-49	-52.5	-171.4	-172.1	174.7	3.5	0	0	112.7	Y319 Q325 I326 D327	Y319-Q323 HydrophobicContact CE1-CG 3.91Å; Y319-Q323 HydrophobicContact CE2-CG 4.27Å; Y319-Q323 WeakPolarHBondContact O-CA 3.46Å; Y319-Q323 VanDerWaalsContact O-CB 3.25Å; Y319-Q323 WeakPolarHBondContact O-CB 3.42Å; Y319-Q323 PolarHBondContact O-N 2.87Å; Y319-Q323 PolarHBondContact OH-NE2 3.15Å; Q323-Q325 VanDerWaalsContact C-N 3.29Å; Q323-Q325 PolarHBondContact O-N 2.81Å; Q323-I326 PolarHBondContact O-N 3.5Å; Q323-D327 WeakPolarHBondContact CG-OD2 3.36Å; Q323-D327 VanDerWaalsContact O-CB 3.28Å; Q323-D327 WeakPolarHBondContact O-CB 3.39Å; Q323-D327 VanDerWaalsContact O-CG 3.31Å; Q323-D327 PolarHBondContact O-N 2.87Å
324	A	91.8	Very high	91.7	Very high	84 Å²	84	87.3 Å²	87.3	69%	0.694	45%	0.448	S	S	*	.	H	α-helix	trans	-61.2	-36.1	-177.5	0	0	0	0	0	113.2	H322 H328	H322-A324 VanDerWaalsContact C-N 3.35Å; H322-A324 PolarHBondContact O-N 3.45Å; A324-H328 VanDerWaalsContact O-CB 3.24Å; A324-H328 WeakPolarHBondContact O-CB 3.37Å; A324-H328 PolarHBondContact O-N 3.26Å
325	Q	92.4	Very high	92	Very high	112 Å²	112	91.8 Å²	91.8	52%	0.523	46%	0.463	S	S	.	.	H	α-helix	trans	-73.8	-48.4	178.2	-67.2	176.2	-26.3	0	0	110.3	H322 Q323 D327 H328 Y329	H322-Q325 PolarHBondContact ND1-OE1 2.79Å; H322-Q325 PolarHBondContact O-N 2.95Å; Q323-Q325 VanDerWaalsContact C-N 3.29Å; Q323-Q325 PolarHBondContact O-N 2.81Å; Q325-D327 PolarHBondContact O-N 2.9Å; Q325-H328 PolarHBondContact O-N 3.5Å; Q325-Y329 HydrophobicContact CB-CE2 4.49Å; Q325-Y329 WeakPolarHBondContact O-CD2 3.18Å; Q325-Y329 PolarHBondContact O-N 3.39Å
326	I	92.8	Very high	92.1	Very high	55 Å²	55	89.8 Å²	89.8	28%	0.282	46%	0.458	S	S	.	.	H	α-helix	trans	-60.8	-48	179.9	-65.4	164.3	0	0	0	110.3	I318 Y319 H322 Q323 H328 Y329 L330	I318-I326 HydrophobicContact CG2-CD1 4.14Å; Y319-I326 HydrophobicContact CD2-CB 4.5Å; Y319-I326 HydrophobicContact CD2-CD1 4.25Å; Y319-I326 HydrophobicContact CD2-CG2 4.1Å; Y319-I326 HydrophobicContact CE2-CG2 4.21Å; H322-I326 HydrophobicContact CB-CD1 3.79Å; H322-I326 HydrophobicContact CB-CG1 4.11Å; H322-I326 WeakPolarHBondContact O-CG1 3.5Å; H322-I326 PolarHBondContact O-N 3.45Å; Q323-I326 PolarHBondContact O-N 3.5Å; I326-H328 VanDerWaalsContact C-N 3.31Å; I326-H328 PolarHBondContact O-N 2.91Å; I326-Y329 PolarHBondContact O-N 3.28Å; I326-L330 WeakPolarHBondContact O-CB 3.44Å; I326-L330 PolarHBondContact O-N 3.29Å
327	D	93.5	Very high	92.5	Very high	64 Å²	64	93.6 Å²	93.6	34%	0.342	48%	0.481	S	S	.	.	H	α-helix	trans	-63.2	-37.5	179.2	-73	-12.7	0	0	0	111.6	Y319 Q323 Q325 G331	Y319-D327 WeakPolarHBondContact CE2-OD1 3.31Å; Y319-D327 PolarHBondContact OH-OD1 2.99Å; Y319-D327 PolarHBondContact OH-OD2 3.45Å; Q323-D327 WeakPolarHBondContact CG-OD2 3.36Å; Q323-D327 VanDerWaalsContact O-CB 3.28Å; Q323-D327 WeakPolarHBondContact O-CB 3.39Å; Q323-D327 VanDerWaalsContact O-CG 3.31Å; Q323-D327 PolarHBondContact O-N 2.87Å; Q325-D327 PolarHBondContact O-N 2.9Å; D327-G331 PolarHBondContact O-N 3.29Å
328	H	93.8	Very high	92.8	Very high	126 Å²	126	98.3 Å²	98.3	58%	0.583	50%	0.497	S	S	*	.	H	α-helix	trans	-63.1	-49.9	174.3	-179.6	73.3	0	0	0	111.9	A324 Q325 I326 G331 L332	A324-H328 VanDerWaalsContact O-CB 3.24Å; A324-H328 WeakPolarHBondContact O-CB 3.37Å; A324-H328 PolarHBondContact O-N 3.26Å; Q325-H328 PolarHBondContact O-N 3.5Å; I326-H328 VanDerWaalsContact C-N 3.31Å; I326-H328 PolarHBondContact O-N 2.91Å; H328-G331 PolarHBondContact O-N 3.24Å; H328-L332 PolarHBondContact O-N 2.83Å
329	Y	93.2	Very high	93.1	Very high	158 Å²	158	97.7 Å²	97.7	62%	0.62	50%	0.495	S	S	*	.	H	α-helix	trans	-66.8	-39.7	178.9	-74.1	-64.6	0	0	0	112.4	Q325 I326 G331 L332 A333	Q325-Y329 HydrophobicContact CB-CE2 4.49Å; Q325-Y329 WeakPolarHBondContact O-CD2 3.18Å; Q325-Y329 PolarHBondContact O-N 3.39Å; I326-Y329 PolarHBondContact O-N 3.28Å; Y329-G331 VanDerWaalsContact C-N 3.33Å; Y329-L332 PolarHBondContact O-N 3.01Å; Y329-A333 WeakPolarHBondContact O-CB 3.48Å; Y329-A333 PolarHBondContact O-N 2.95Å
330	L	93.5	Very high	93.3	Very high	94 Å²	94	96.1 Å²	96.1	49%	0.492	50%	0.498	S	S	.	.	H	α-helix	trans	-66.2	-38.2	176.3	-170.1	65.2	0	0	0	110.9	I326 A333 N334	I326-L330 WeakPolarHBondContact O-CB 3.44Å; I326-L330 PolarHBondContact O-N 3.29Å; L330-A333 PolarHBondContact O-N 2.92Å; L330-N334 VanDerWaalsContact O-CB 3.24Å; L330-N334 WeakPolarHBondContact O-CB 3.24Å; L330-N334 VanDerWaalsContact O-CG 3.31Å; L330-N334 PolarHBondContact O-N 3.04Å; L330-N334 PolarHBondContact O-ND2 3.14Å; L330-N334 VanDerWaalsContact O-ND2 3.09Å
331	G	94	Very high	93.6	Very high	40 Å²	40	94.9 Å²	94.9	41%	0.412	49%	0.494	S	S	.	.	H	α-helix	trans	-61	-45.1	171.8	0	0	0	0	0	112.2	D327 H328 Y329 N334 K335	D327-G331 PolarHBondContact O-N 3.29Å; H328-G331 PolarHBondContact O-N 3.24Å; Y329-G331 VanDerWaalsContact C-N 3.33Å; G331-N334 PolarHBondContact O-N 2.84Å; G331-K335 WeakPolarHBondContact O-CB 3.49Å; G331-K335 PolarHBondContact O-N 2.95Å
332	L	95.2	Very high	93.7	Very high	92 Å²	92	87.4 Å²	87.4	48%	0.482	48%	0.476	S	S	.	.	H	α-helix	trans	-66.3	-42.3	177.3	-173.6	62.5	0	0	0	112.3	H328 Y329 K335 S336	H328-L332 PolarHBondContact O-N 2.83Å; Y329-L332 PolarHBondContact O-N 3.01Å; L332-K335 PolarHBondContact O-N 3.41Å; L332-S336 WeakPolarHBondContact O-CB 3.35Å; L332-S336 PolarHBondContact O-N 3.41Å; L332-S336 PolarHBondContact O-OG 3.27Å
333	A	95.9	Very high	93.7	Very high	49 Å²	49	90.8 Å²	90.8	41%	0.405	49%	0.489	S	S	.	.	H	α-helix	trans	-62.5	-48.2	175.2	0	0	0	0	0	111	Y329 L330 K335 S336 V337	Y329-A333 WeakPolarHBondContact O-CB 3.48Å; Y329-A333 PolarHBondContact O-N 2.95Å; L330-A333 PolarHBondContact O-N 2.92Å; A333-K335 VanDerWaalsContact C-N 3.32Å; A333-K335 PolarHBondContact O-N 3.41Å; A333-S336 PolarHBondContact O-N 2.87Å; A333-S336 VanDerWaalsContact O-N 3.13Å; A333-V337 WeakPolarHBondContact O-CG2 3.49Å; A333-V337 PolarHBondContact O-N 3.45Å
334	N	96	Very high	93.9	Very high	80 Å²	80	90.6 Å²	90.6	43%	0.428	49%	0.491	S	S	.	.	H	α-helix	trans	-59.6	-41.3	176.3	-83.2	-41.6	0	0	0	112.3	L330 G331 K338	L330-N334 VanDerWaalsContact O-CB 3.24Å; L330-N334 WeakPolarHBondContact O-CB 3.24Å; L330-N334 VanDerWaalsContact O-CG 3.31Å; L330-N334 PolarHBondContact O-N 3.04Å; L330-N334 PolarHBondContact O-ND2 3.14Å; L330-N334 VanDerWaalsContact O-ND2 3.09Å; G331-N334 PolarHBondContact O-N 2.84Å; N334-K338 WeakPolarHBondContact O-CB 3.27Å; N334-K338 VanDerWaalsContact O-CG 3.24Å; N334-K338 WeakPolarHBondContact O-CG 3.36Å; N334-K338 PolarHBondContact O-N 3.32Å
335	K	95.2	Very high	93.7	Very high	131 Å²	131	92.5 Å²	92.5	57%	0.57	49%	0.485	S	S	*	.	H	α-helix	trans	-62.4	-46.6	174.3	-174.3	177.2	179.7	179.7	0	111	G331 L332 A333 V337 K338 D339	G331-K335 WeakPolarHBondContact O-CB 3.49Å; G331-K335 PolarHBondContact O-N 2.95Å; L332-K335 PolarHBondContact O-N 3.41Å; A333-K335 VanDerWaalsContact C-N 3.32Å; A333-K335 PolarHBondContact O-N 3.41Å; K335-V337 VanDerWaalsContact C-N 3.35Å; K335-V337 PolarHBondContact O-N 2.85Å; K335-K338 PolarHBondContact O-N 2.81Å; K335-D339 WeakPolarHBondContact O-CB 3.34Å; K335-D339 VanDerWaalsContact O-CG 3.22Å; K335-D339 PolarHBondContact O-N 2.96Å
336	S	94.8	Very high	93.5	Very high	64 Å²	64	91 Å²	91	45%	0.448	49%	0.491	S	S	.	.	H	α-helix	trans	-62.6	-40.9	179.4	-56.1	0	0	0	0	112.1	L332 A333 A340	L332-S336 WeakPolarHBondContact O-CB 3.35Å; L332-S336 PolarHBondContact O-N 3.41Å; L332-S336 PolarHBondContact O-OG 3.27Å; A333-S336 PolarHBondContact O-N 2.87Å; A333-S336 VanDerWaalsContact O-N 3.13Å; S336-A340 VanDerWaalsContact O-CB 3.25Å; S336-A340 WeakPolarHBondContact O-CB 3.36Å; S336-A340 PolarHBondContact O-N 3.47Å
337	V	95.6	Very high	93.2	Very high	97 Å²	97	96.8 Å²	96.8	59%	0.588	52%	0.515	S	S	*	.	H	α-helix	trans	-65.7	-44.8	174.9	171.2	0	0	0	0	111	A333 K335 A340 M341	A333-V337 WeakPolarHBondContact O-CG2 3.49Å; A333-V337 PolarHBondContact O-N 3.45Å; K335-V337 VanDerWaalsContact C-N 3.35Å; K335-V337 PolarHBondContact O-N 2.85Å; V337-A340 PolarHBondContact O-N 2.73Å; V337-M341 VanDerWaalsContact O-CB 3.27Å; V337-M341 WeakPolarHBondContact O-CB 3.28Å; V337-M341 PolarHBondContact O-N 2.89Å
338	K	95.2	Very high	92.6	Very high	150 Å²	150	98.4 Å²	98.4	65%	0.652	52%	0.523	S	S	*	.	H	α-helix	trans	-63.1	-42.8	176.2	-75	174.8	-177.6	179.9	0	111.9	N334 K335 M341 A342	N334-K338 WeakPolarHBondContact O-CB 3.27Å; N334-K338 VanDerWaalsContact O-CG 3.24Å; N334-K338 WeakPolarHBondContact O-CG 3.36Å; N334-K338 PolarHBondContact O-N 3.32Å; K335-K338 PolarHBondContact O-N 2.81Å; K338-M341 PolarHBondContact O-N 3.48Å; K338-A342 VanDerWaalsContact O-CB 3.28Å; K338-A342 WeakPolarHBondContact O-CB 3.24Å; K338-A342 PolarHBondContact O-N 2.9Å
339	D	95.1	Very high	91.3	Very high	77 Å²	77	98.3 Å²	98.3	41%	0.412	53%	0.533	S	S	.	.	H	α-helix	trans	-66	-40.9	177.4	-71.6	-14	0	0	0	111.2	K335 A342 K343	K335-D339 WeakPolarHBondContact O-CB 3.34Å; K335-D339 VanDerWaalsContact O-CG 3.22Å; K335-D339 PolarHBondContact O-N 2.96Å; D339-A342 PolarHBondContact O-N 3.4Å; D339-K343 WeakPolarHBondContact O-CB 3.46Å; D339-K343 VanDerWaalsContact O-CG 3.27Å; D339-K343 WeakPolarHBondContact O-CG 3.19Å; D339-K343 PolarHBondContact O-N 3.22Å
340	A	94.4	Very high	90	Very high	46 Å²	46	93.5 Å²	93.5	38%	0.38	53%	0.532	S	S	.	.	H	α-helix	trans	-63.9	-45.9	173.5	0	0	0	0	0	111.4	S336 V337 A342 K343 I344	S336-A340 VanDerWaalsContact O-CB 3.25Å; S336-A340 WeakPolarHBondContact O-CB 3.36Å; S336-A340 PolarHBondContact O-N 3.47Å; V337-A340 PolarHBondContact O-N 2.73Å; A340-A342 VanDerWaalsContact C-N 3.35Å; A340-A342 PolarHBondContact O-N 2.84Å; A340-K343 PolarHBondContact O-N 3Å; A340-I344 WeakPolarHBondContact O-CB 3.37Å; A340-I344 VanDerWaalsContact O-CG1 3.25Å; A340-I344 WeakPolarHBondContact O-CG1 3.19Å; A340-I344 PolarHBondContact O-N 3.21Å
341	M	92.8	Very high	88.1	Confident	98 Å²	98	97 Å²	97	48%	0.483	55%	0.55	S	S	.	.	H	α-helix	trans	-60.9	-43.1	176	-173.7	63.1	179.4	0	0	111.4	V337 K338 I344 Q345	V337-M341 VanDerWaalsContact O-CB 3.27Å; V337-M341 WeakPolarHBondContact O-CB 3.28Å; V337-M341 PolarHBondContact O-N 2.89Å; K338-M341 PolarHBondContact O-N 3.48Å; M341-I344 PolarHBondContact O-N 3.47Å; M341-Q345 HydrophobicContact CE-CG 4.23Å; M341-Q345 WeakPolarHBondContact O-CB 3.4Å; M341-Q345 VanDerWaalsContact O-CG 3.31Å; M341-Q345 WeakPolarHBondContact O-CG 3.42Å; M341-Q345 PolarHBondContact O-N 3.38Å
342	A	92	Very high	86.2	Confident	49 Å²	49	104.9 Å²	104.9	41%	0.405	57%	0.573	S	S	.	*	H	α-helix	trans	-64.2	-40.7	176.7	0	0	0	0	0	111.9	K338 D339 A340 Q345 A346	K338-A342 VanDerWaalsContact O-CB 3.28Å; K338-A342 WeakPolarHBondContact O-CB 3.24Å; K338-A342 PolarHBondContact O-N 2.9Å; D339-A342 PolarHBondContact O-N 3.4Å; A340-A342 VanDerWaalsContact C-N 3.35Å; A340-A342 PolarHBondContact O-N 2.84Å; A342-Q345 PolarHBondContact O-N 3.4Å; A342-A346 WeakPolarHBondContact O-CB 3.18Å; A342-A346 PolarHBondContact O-N 2.98Å
343	K	92	Very high	83.8	Confident	146 Å²	146	112 Å²	112	64%	0.635	59%	0.593	S	S	*	*	H	α-helix	trans	-64.8	-41.1	173.8	-74.1	171.9	-174.7	175.3	0	112	D339 A340 A346 K347	D339-K343 WeakPolarHBondContact O-CB 3.46Å; D339-K343 VanDerWaalsContact O-CG 3.27Å; D339-K343 WeakPolarHBondContact O-CG 3.19Å; D339-K343 PolarHBondContact O-N 3.22Å; A340-K343 PolarHBondContact O-N 3Å; K343-A346 PolarHBondContact O-N 3.48Å; K343-K347 WeakPolarHBondContact O-CB 3.33Å; K343-K347 WeakPolarHBondContact O-CG 3.39Å; K343-K347 PolarHBondContact O-N 3.37Å
344	I	91.7	Very high	81.3	Confident	91 Å²	91	119.3 Å²	119.3	47%	0.467	62%	0.616	S	S	.	*	H	α-helix	trans	-63.4	-47	175.2	-69	163.9	0	0	0	109.5	A340 M341 A346 K347 I348	A340-I344 WeakPolarHBondContact O-CB 3.37Å; A340-I344 VanDerWaalsContact O-CG1 3.25Å; A340-I344 WeakPolarHBondContact O-CG1 3.19Å; A340-I344 PolarHBondContact O-N 3.21Å; M341-I344 PolarHBondContact O-N 3.47Å; I344-A346 VanDerWaalsContact C-N 3.34Å; I344-A346 PolarHBondContact O-N 2.9Å; I344-K347 CarbonylContact O-C 3.59Å; I344-K347 PolarHBondContact O-N 3.29Å; I344-K347 VanDerWaalsContact O-N 3.14Å; I344-I348 HydrophobicContact CG2-CD1 3.58Å; I344-I348 HydrophobicContact CG2-CG1 4.3Å; I344-I348 VanDerWaalsContact O-CG1 3.27Å; I344-I348 WeakPolarHBondContact O-CG1 3.4Å; I344-I348 PolarHBondContact O-N 2.93Å
345	Q	88.5	Confident	78.6	Confident	123 Å²	123	120.2 Å²	120.2	58%	0.575	63%	0.634	S	S	*	*	H	α-helix	trans	-61.5	-38.4	176.1	-75.4	180	-29.1	0	0	112.9	M341 A342 K347 I348	M341-Q345 HydrophobicContact CE-CG 4.23Å; M341-Q345 WeakPolarHBondContact O-CB 3.4Å; M341-Q345 VanDerWaalsContact O-CG 3.31Å; M341-Q345 WeakPolarHBondContact O-CG 3.42Å; M341-Q345 PolarHBondContact O-N 3.38Å; A342-Q345 PolarHBondContact O-N 3.4Å; Q345-K347 VanDerWaalsContact C-N 3.34Å; Q345-I348 PolarHBondContact O-N 3.21Å
346	A	88	Confident	76	Confident	80 Å²	80	126.6 Å²	126.6	66%	0.661	67%	0.666	S	S	*	*	H	α-helix	trans	-69.1	-32.8	175.4	0	0	0	0	0	112.4	A342 K343 I344	A342-A346 WeakPolarHBondContact O-CB 3.18Å; A342-A346 PolarHBondContact O-N 2.98Å; K343-A346 PolarHBondContact O-N 3.48Å; I344-A346 VanDerWaalsContact C-N 3.34Å; I344-A346 PolarHBondContact O-N 2.9Å
347	K	86.4	Confident	75	Confident	177 Å²	177	129.7 Å²	129.7	77%	0.77	68%	0.677	S	S	*	*	H	α-helix	trans	-84.1	-13.6	177.3	-75.7	-170.7	176.6	-170.2	0	114.3	K343 I344 Q345 P349	K343-K347 WeakPolarHBondContact O-CB 3.33Å; K343-K347 WeakPolarHBondContact O-CG 3.39Å; K343-K347 PolarHBondContact O-N 3.37Å; I344-K347 CarbonylContact O-C 3.59Å; I344-K347 PolarHBondContact O-N 3.29Å; I344-K347 VanDerWaalsContact O-N 3.14Å; Q345-K347 VanDerWaalsContact C-N 3.34Å; K347-P349 WeakPolarHBondContact O-CD 3.07Å
348	I	82.2	Confident	74	Confident	99 Å²	99	131.4 Å²	131.4	51%	0.508	68%	0.682	S	S	.	*	S	Bend	trans	-94	84.4	168.8	-62.1	169.5	0	0	0	106.5	I344 Q345 G350	I344-I348 HydrophobicContact CG2-CD1 3.58Å; I344-I348 HydrophobicContact CG2-CG1 4.3Å; I344-I348 VanDerWaalsContact O-CG1 3.27Å; I344-I348 WeakPolarHBondContact O-CG1 3.4Å; I344-I348 PolarHBondContact O-N 2.93Å; Q345-I348 PolarHBondContact O-N 3.21Å; I348-G350 VanDerWaalsContact C-N 3.35Å; I348-G350 PolarHBondContact O-N 3.28Å
349	P	66	Low	72.8	Confident	124 Å²	124	130.4 Å²	130.4	81%	0.805	68%	0.683	S	S	*	*	T	Hydrogen-bonded Turn	trans	-83.8	84.6	-173.6	9.1	15.3	0	0	0	106	K347	K347-P349 WeakPolarHBondContact O-CD 3.07Å
350	G	65.3	Low	71.5	Confident	57 Å²	57	133.5 Å²	133.5	59%	0.588	70%	0.699	S	S	*	*	T	Hydrogen-bonded Turn	trans	-177.2	-19.1	-175.6	0	0	0	0	0	118.5	I348	I348-G350 VanDerWaalsContact C-N 3.35Å; I348-G350 PolarHBondContact O-N 3.28Å
351	L	53.6	Low	70	Confident	166 Å²	166	139 Å²	139	87%	0.869	72%	0.719	S	S	*	*	T	Hydrogen-bonded Turn	trans	-95	2.1	-175.5	-124.4	72.7	0	0	0	115.6
352	K	53.8	Low	68.5	Low	207 Å²	207	141.7 Å²	141.7	90%	0.9	74%	0.735	S	S	*	*	T	Hydrogen-bonded Turn	trans	-111.6	26.4	174.6	-70.6	-156	-178.8	-170.2	0	114.9
353	R	45.7	Very low	66.9	Low	240 Å²	240	148.4 Å²	148.4	91%	0.906	76%	0.758	S	S	*	*			trans	-100	70	160.3	-99.2	-172	153.6	120.8	-2.5	110.6
354	K	43	Very low	64.9	Low	204 Å²	204	148.5 Å²	148.5	89%	0.887	77%	0.768	S	S	*	*			trans	-140.6	72.3	146.8	-77.8	-159	178	-170.3	0	107.4
355	A	40.4	Very low	62.7	Low	98 Å²	98	153.3 Å²	153.3	81%	0.81	79%	0.793	S	S	*	*			trans	-119.8	72.4	156.7	0	0	0	0	0	105.1
356	E	39.5	Very low	60.3	Low	265 Å²	265	156.1 Å²	156.1	100%	1.238	81%	0.813	S	S	*	*			trans	-169.4	0	144	-130.7	173.4	123.9	0	0	109

Retrieved 356 of 356 residues in 396.1 ms (Link to these results)

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