Q99PH5_MOUSE Loading...

Insulinoma associated-2

AlphaFold DB , UniProt , Accession Q99PH5, Species MOUSE (Mus musculus, Mouse), Gene IA-2, Length 41 aa.

						>Q99PH5_MOUSE|Q99PH5|IA-2
MRRPRRPGGSGGSGGSGGLRLLVCLLLLSGRPGGCSAISAH
					

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	42.4	Very low	58.2	Low	242 Å²	242	163.6 Å²	163.6	100%	1.192	87%	0.872	S	S	*	*				0	102.6	0	-63.6	161.5	77.3	0	0	109	R3	M1-R3 PolarHBondContact O-N 3.2Å
2	R	58.7	Low	58.2	Low	254 Å²	254	155.8 Å²	155.8	96%	0.958	86%	0.859	S	S	*	*			trans	-68.6	110	173.2	-91.8	178.3	163.2	-153	-2	107.7
3	R	64.4	Low	58.1	Low	233 Å²	233	151.7 Å²	151.7	88%	0.879	85%	0.848	S	S	*	*			trans	-55.6	131	169.9	-87.7	-176.8	178.5	-169.2	-0.2	108.2	M1 R5	M1-R3 PolarHBondContact O-N 3.2Å; R3-R5 PolarHBondContact O-N 3.07Å; R3-R5 VanDerWaalsContact O-N 3.07Å
4	P	58.8	Low	58.4	Low	117 Å²	117	147.6 Å²	147.6	76%	0.76	86%	0.858	S	S	*	*			trans	-60.7	116.6	168.7	-5.1	17.3	0	0	0	106.9	R6	P4-R6 PolarHBondContact O-N 3.24Å
5	R	62.1	Low	58.3	Low	245 Å²	245	140.8 Å²	140.8	93%	0.925	83%	0.831	S	S	*	*			trans	-67.5	94.6	162.8	-67.6	-177.5	-174.9	174.2	0.6	104.8	R3 P7	R3-R5 PolarHBondContact O-N 3.07Å; R3-R5 VanDerWaalsContact O-N 3.07Å; R5-P7 VanDerWaalsContact O-N 3.09Å; R5-P7 WeakPolarHBondContact O-CD 3.34Å
6	R	57.9	Low	58.5	Low	227 Å²	227	136.7 Å²	136.7	86%	0.857	81%	0.812	S	S	*	*			trans	-45.1	118.9	176.7	-93.8	-175.1	170.1	-176.7	-2.8	108.1	P4 G8	P4-R6 PolarHBondContact O-N 3.24Å; R6-G8 PolarHBondContact O-N 2.91Å
7	P	62	Low	59.4	Low	132 Å²	132	131.1 Å²	131.1	86%	0.857	79%	0.789	S	S	*	*			trans	-77.3	102.9	162.1	30.6	-24.1	0	0	0	105.1	R5	R5-P7 VanDerWaalsContact O-N 3.09Å; R5-P7 WeakPolarHBondContact O-CD 3.34Å
8	G	53.8	Low	60.4	Low	71 Å²	71	126.1 Å²	126.1	73%	0.732	77%	0.769	S	S	*	*			trans	159.8	123.9	175.3	0	0	0	0	0	114.6	R6	R6-G8 PolarHBondContact O-N 2.91Å
9	G	54.2	Low	61.5	Low	64 Å²	64	125.2 Å²	125.2	66%	0.66	76%	0.759	S	S	*	*			trans	122.9	74.7	156.6	0	0	0	0	0	113.4	G11	G9-G11 PolarHBondContact O-N 3.14Å; G9-G11 VanDerWaalsContact O-N 3.14Å
10	S	60	Low	62.5	Low	134 Å²	134	128.3 Å²	128.3	94%	0.937	76%	0.756	S	S	*	*				-8	106.5	127.8	44.3	0	0	0	0	113.4
11	G	65.6	Low	63.4	Low	81 Å²	81	128.3 Å²	128.3	84%	0.835	75%	0.752	S	S	*	*			trans	171.2	69.7	-179	0	0	0	0	0	114.4	G9	G9-G11 PolarHBondContact O-N 3.14Å; G9-G11 VanDerWaalsContact O-N 3.14Å
12	G	58.6	Low	65.5	Low	70 Å²	70	122 Å²	122	72%	0.722	72%	0.723	S	S	*	*	S	Bend	trans	-175.1	89.7	168.9	0	0	0	0	0	111.9
13	S	57.4	Low	66.7	Low	102 Å²	102	113.6 Å²	113.6	71%	0.713	70%	0.699	S	S	*	*			trans	84.5	66.4	-176.8	74.5	0	0	0	0	116.2	G15	S13-G15 PolarHBondContact O-N 3.43Å
14	G	61.3	Low	67.6	Low	95 Å²	95	106 Å²	106	98%	0.979	68%	0.681	S	S	*	*	T	Hydrogen-bonded Turn	trans	-64.5	74.7	170	0	0	0	0	0	113.4
15	G	57.6	Low	68.8	Low	45 Å²	45	105.1 Å²	105.1	46%	0.464	67%	0.67	S	S	.	*	T	Hydrogen-bonded Turn	trans	-151.2	-38.3	168.1	0	0	0	0	0	111.6	S13 L19	S13-G15 PolarHBondContact O-N 3.43Å; G15-L19 VanDerWaalsContact O-CD1 3.31Å; G15-L19 WeakPolarHBondContact O-CD1 3.31Å; G15-L19 VanDerWaalsContact O-CG 3.28Å; G15-L19 WeakPolarHBondContact O-CG 3.29Å
16	S	61.5	Low	69.9	Low	75 Å²	75	99.4 Å²	99.4	52%	0.524	66%	0.657	S	S	.	*	H	α-helix	trans	-85.6	-34.3	-176.9	73.8	0	0	0	0	114.1	L19 R20	S16-L19 PolarHBondContact O-N 2.92Å; S16-R20 WeakPolarHBondContact O-CB 3.33Å; S16-R20 WeakPolarHBondContact O-CG 3.26Å; S16-R20 PolarHBondContact O-N 2.82Å
17	G	72.9	Confident	71	Confident	41 Å²	41	94.6 Å²	94.6	42%	0.423	65%	0.647	S	S	.	*	H	α-helix	trans	-64.9	-42.9	-179.6	0	0	0	0	0	112.5	R20 L21	G17-R20 PolarHBondContact O-N 3.11Å; G17-L21 VanDerWaalsContact O-CG 3.3Å; G17-L21 WeakPolarHBondContact O-CG 3.44Å; G17-L21 PolarHBondContact O-N 3.45Å
18	G	77.9	Confident	71.8	Confident	41 Å²	41	95.1 Å²	95.1	42%	0.423	64%	0.642	S	S	.	*	H	α-helix	trans	-65.6	-43.3	175.7	0	0	0	0	0	112.6	R20 L21 L22	G18-R20 VanDerWaalsContact C-N 3.34Å; G18-R20 PolarHBondContact O-N 3.44Å; G18-L21 PolarHBondContact O-N 2.83Å; G18-L21 VanDerWaalsContact O-N 3.17Å; G18-L22 VanDerWaalsContact O-CG 3.31Å; G18-L22 WeakPolarHBondContact O-CG 3.45Å; G18-L22 PolarHBondContact O-N 3.26Å
19	L	80.5	Confident	72.7	Confident	110 Å²	110	94.6 Å²	94.6	58%	0.576	63%	0.627	S	S	*	*	H	α-helix	trans	-62	-40.9	174.7	-72	170.4	0	0	0	112	G15 S16 L21 L22 V23	G15-L19 VanDerWaalsContact O-CD1 3.31Å; G15-L19 WeakPolarHBondContact O-CD1 3.31Å; G15-L19 VanDerWaalsContact O-CG 3.28Å; G15-L19 WeakPolarHBondContact O-CG 3.29Å; S16-L19 PolarHBondContact O-N 2.92Å; L19-L21 VanDerWaalsContact C-N 3.32Å; L19-L21 PolarHBondContact O-N 3.41Å; L19-L22 HydrophobicContact CD2-CD1 4.49Å; L19-L22 PolarHBondContact O-N 3.44Å; L19-V23 WeakPolarHBondContact O-CG2 3.28Å; L19-V23 PolarHBondContact O-N 3.32Å; L19-V23 VanDerWaalsContact O-CG2 3.29Å; L19-V23 WeakPolarHBondContact O-CB 3.23Å
20	R	81.8	Confident	73.1	Confident	187 Å²	187	93.9 Å²	93.9	71%	0.706	62%	0.62	S	S	*	*	H	α-helix	trans	-61.6	-41.4	173.7	-76.5	-76.2	-77.8	-133	-3	111.4	S16 G17 G18 C24	S16-R20 WeakPolarHBondContact O-CB 3.33Å; S16-R20 WeakPolarHBondContact O-CG 3.26Å; S16-R20 PolarHBondContact O-N 2.82Å; G17-R20 PolarHBondContact O-N 3.11Å; G18-R20 VanDerWaalsContact C-N 3.34Å; G18-R20 PolarHBondContact O-N 3.44Å; R20-C24 VanDerWaalsContact O-CB 3.28Å; R20-C24 WeakPolarHBondContact O-CB 3.28Å; R20-C24 PolarHBondContact O-N 3.48Å; R20-C24 PolarHBondContact O-SG 3Å
21	L	82.4	Confident	73.1	Confident	128 Å²	128	98.9 Å²	98.9	67%	0.67	62%	0.618	S	S	*	*	H	α-helix	trans	-66.6	-41.8	175.5	-68.1	175	0	0	0	112.2	G17 G18 L19 C24 L25	G17-L21 VanDerWaalsContact O-CG 3.3Å; G17-L21 WeakPolarHBondContact O-CG 3.44Å; G17-L21 PolarHBondContact O-N 3.45Å; G18-L21 PolarHBondContact O-N 2.83Å; G18-L21 VanDerWaalsContact O-N 3.17Å; L19-L21 VanDerWaalsContact C-N 3.32Å; L19-L21 PolarHBondContact O-N 3.41Å; L21-C24 PolarHBondContact O-N 3.17Å; L21-L25 VanDerWaalsContact O-CB 3.23Å; L21-L25 WeakPolarHBondContact O-CB 3.4Å; L21-L25 PolarHBondContact O-N 2.86Å
22	L	86.6	Confident	72.7	Confident	111 Å²	111	99.5 Å²	99.5	58%	0.581	61%	0.608	S	S	*	*	H	α-helix	trans	-62.9	-42.8	175.6	-71.2	171.1	0	0	0	111.8	G18 L19 L25 L26	G18-L22 VanDerWaalsContact O-CG 3.31Å; G18-L22 WeakPolarHBondContact O-CG 3.45Å; G18-L22 PolarHBondContact O-N 3.26Å; L19-L22 HydrophobicContact CD2-CD1 4.49Å; L19-L22 PolarHBondContact O-N 3.44Å; L22-L25 PolarHBondContact O-N 2.85Å; L22-L26 WeakPolarHBondContact O-CB 3.31Å; L22-L26 VanDerWaalsContact O-CB 3.26Å; L22-L26 PolarHBondContact O-N 3.46Å
23	V	82.8	Confident	72.7	Confident	77 Å²	77	98.8 Å²	98.8	47%	0.467	60%	0.6	S	S	.	*	H	α-helix	trans	-68.7	-43.1	176.1	171.6	0	0	0	0	111.1	L19 L25 L26 L27	L19-V23 WeakPolarHBondContact O-CG2 3.28Å; L19-V23 PolarHBondContact O-N 3.32Å; L19-V23 VanDerWaalsContact O-CG2 3.29Å; L19-V23 WeakPolarHBondContact O-CB 3.23Å; V23-L25 VanDerWaalsContact C-N 3.3Å; V23-L25 PolarHBondContact O-N 2.83Å; V23-L26 PolarHBondContact O-N 2.81Å; V23-L27 HydrophobicContact CG1-CD1 3.89Å; V23-L27 HydrophobicContact CG1-CG 4.29Å; V23-L27 WeakPolarHBondContact O-CB 3.4Å; V23-L27 VanDerWaalsContact O-CG 3.26Å; V23-L27 WeakPolarHBondContact O-CG 2.89Å; V23-L27 PolarHBondContact O-N 3.38Å
24	C	83.1	Confident	72.8	Confident	72 Å²	72	98.4 Å²	98.4	49%	0.486	61%	0.613	S	S	.	*	H	α-helix	trans	-60.7	-41.7	174.3	-72.8	0	0	0	0	111.3	R20 L21 L27 L28	R20-C24 VanDerWaalsContact O-CB 3.28Å; R20-C24 WeakPolarHBondContact O-CB 3.28Å; R20-C24 PolarHBondContact O-N 3.48Å; R20-C24 PolarHBondContact O-SG 3Å; L21-C24 PolarHBondContact O-N 3.17Å; C24-L27 PolarHBondContact O-N 2.84Å; C24-L28 WeakPolarHBondContact O-CB 3.26Å; C24-L28 PolarHBondContact O-N 2.78Å
25	L	85	Confident	72.6	Confident	100 Å²	100	99 Å²	99	52%	0.524	60%	0.6	S	S	.	*	H	α-helix	trans	-67.1	-42.5	175.7	-172.2	64.1	0	0	0	110.7	L21 L22 V23 L27 L28 S29	L21-L25 VanDerWaalsContact O-CB 3.23Å; L21-L25 WeakPolarHBondContact O-CB 3.4Å; L21-L25 PolarHBondContact O-N 2.86Å; L22-L25 PolarHBondContact O-N 2.85Å; V23-L25 VanDerWaalsContact C-N 3.3Å; V23-L25 PolarHBondContact O-N 2.83Å; L25-L27 VanDerWaalsContact C-N 3.34Å; L25-L27 PolarHBondContact O-N 3.23Å; L25-L28 PolarHBondContact O-N 3.44Å; L25-S29 WeakPolarHBondContact O-CA 2.73Å; L25-S29 WeakPolarHBondContact O-CB 3.48Å; L25-S29 PolarHBondContact O-N 3.47Å; L25-S29 PolarHBondContact O-OG 2.78Å
26	L	84	Confident	72.5	Confident	125 Å²	125	101.9 Å²	101.9	65%	0.654	61%	0.614	S	S	*	*	H	α-helix	trans	-64.7	-34.5	175.9	-178.9	64.1	0	0	0	112.5	L22 V23 G30	L22-L26 WeakPolarHBondContact O-CB 3.31Å; L22-L26 VanDerWaalsContact O-CB 3.26Å; L22-L26 PolarHBondContact O-N 3.46Å; V23-L26 PolarHBondContact O-N 2.81Å; L26-G30 WeakPolarHBondContact O-CA 3.3Å; L26-G30 PolarHBondContact O-N 3.4Å
27	L	82.6	Confident	72.4	Confident	126 Å²	126	102.7 Å²	102.7	66%	0.66	62%	0.624	S	S	*	*	H	α-helix	trans	-77.2	-38.5	175.9	-70.6	172.7	0	0	0	112	V23 C24 L25 G30	V23-L27 HydrophobicContact CG1-CD1 3.89Å; V23-L27 HydrophobicContact CG1-CG 4.29Å; V23-L27 WeakPolarHBondContact O-CB 3.4Å; V23-L27 VanDerWaalsContact O-CG 3.26Å; V23-L27 WeakPolarHBondContact O-CG 2.89Å; V23-L27 PolarHBondContact O-N 3.38Å; C24-L27 PolarHBondContact O-N 2.84Å; L25-L27 VanDerWaalsContact C-N 3.34Å; L25-L27 PolarHBondContact O-N 3.23Å; L27-G30 WeakPolarHBondContact O-CA 3.1Å; L27-G30 PolarHBondContact O-N 2.66Å
28	L	79.1	Confident	71.8	Confident	142 Å²	142	107.9 Å²	107.9	74%	0.743	64%	0.641	S	S	*	*	H	α-helix	trans	-67.3	-45.9	175.5	-179.6	64.7	0	0	0	110.9	C24 L25 G30	C24-L28 WeakPolarHBondContact O-CB 3.26Å; C24-L28 PolarHBondContact O-N 2.78Å; L25-L28 PolarHBondContact O-N 3.44Å; L28-G30 VanDerWaalsContact C-N 3.28Å
29	S	71.4	Confident	71.1	Confident	61 Å²	61	110.5 Å²	110.5	43%	0.427	65%	0.653	S	S	.	*	H	α-helix	trans	-64.6	-38.8	168.7	-66	0	0	0	0	109.5	L25 R31 P32	L25-S29 WeakPolarHBondContact O-CA 2.73Å; L25-S29 WeakPolarHBondContact O-CB 3.48Å; L25-S29 PolarHBondContact O-N 3.47Å; L25-S29 PolarHBondContact O-OG 2.78Å; S29-R31 CarbonylContact O-C 3.17Å; S29-R31 WeakPolarHBondContact O-CA 3.36Å; S29-R31 PolarHBondContact O-N 2.7Å; S29-P32 WeakPolarHBondContact O-CG 3.08Å; S29-P32 WeakPolarHBondContact O-CD 3.43Å; S29-P32 WeakPolarHBondContact O-CB 2.93Å; S29-P32 VanDerWaalsContact C-CD 3.48Å
30	G	62.7	Low	69.9	Low	49 Å²	49	110.5 Å²	110.5	51%	0.505	67%	0.669	S	S	.	*	T	Hydrogen-bonded Turn	trans	-47.4	-0.6	-176.6	0	0	0	0	0	118.3	L26 L27 L28 P32	L26-G30 WeakPolarHBondContact O-CA 3.3Å; L26-G30 PolarHBondContact O-N 3.4Å; L27-G30 WeakPolarHBondContact O-CA 3.1Å; L27-G30 PolarHBondContact O-N 2.66Å; L28-G30 VanDerWaalsContact C-N 3.28Å; G30-P32 VanDerWaalsContact CA-CD 3.42Å
31	R	61.1	Low	68.5	Low	238 Å²	238	112.6 Å²	112.6	90%	0.898	69%	0.686	S	S	*	*			trans	-97.4	39.2	152	-66.2	-179.8	155.4	-165.9	-5.9	113.2	S29 G33	S29-R31 CarbonylContact O-C 3.17Å; S29-R31 WeakPolarHBondContact O-CA 3.36Å; S29-R31 PolarHBondContact O-N 2.7Å; R31-G33 PolarHBondContact O-N 3Å
32	P	57.4	Low	67.9	Low	95 Å²	95	111.8 Å²	111.8	62%	0.617	69%	0.687	S	S	*	*	S	Bend	trans	-105.2	69.5	172.5	39.5	-16.4	0	0	0	105.5	S29 G30	S29-P32 WeakPolarHBondContact O-CG 3.08Å; S29-P32 WeakPolarHBondContact O-CD 3.43Å; S29-P32 WeakPolarHBondContact O-CB 2.93Å; S29-P32 VanDerWaalsContact C-CD 3.48Å; G30-P32 VanDerWaalsContact CA-CD 3.42Å
33	G	57	Low	66.9	Low	55 Å²	55	111.8 Å²	111.8	57%	0.567	69%	0.692	S	S	*	*			trans	48.2	106.5	169.1	0	0	0	0	0	116.4	R31 C35	R31-G33 PolarHBondContact O-N 3Å; G33-C35 PolarHBondContact O-N 2.79Å; G33-C35 PolarHBondContact O-SG 3.43Å
34	G	60.9	Low	66	Low	94 Å²	94	113.8 Å²	113.8	97%	0.969	71%	0.705	S	S	*	*			trans	-53.2	98.7	160.7	0	0	0	0	0	111.7
35	C	56.2	Low	65	Low	106 Å²	106	116.2 Å²	116.2	72%	0.716	72%	0.718	S	S	*	*			trans	-146.5	82.5	161	41.9	0	0	0	0	107.3	G33 A37	G33-C35 PolarHBondContact O-N 2.79Å; G33-C35 PolarHBondContact O-SG 3.43Å; C35-A37 PolarHBondContact O-N 2.96Å
36	S	55.6	Low	63.7	Low	107 Å²	107	117.3 Å²	117.3	75%	0.748	73%	0.73	S	S	*	*			trans	-54.5	81.8	142.1	-78	0	0	0	0	107.4	I38	S36-I38 PolarHBondContact O-N 2.77Å
37	A	58.9	Low	62.4	Low	91 Å²	91	116.7 Å²	116.7	75%	0.752	74%	0.735	S	S	*	*			trans	-76.6	58.5	158.6	0	0	0	0	0	107.3	C35 S39	C35-A37 PolarHBondContact O-N 2.96Å; A37-S39 PolarHBondContact O-N 3.08Å; A37-S39 VanDerWaalsContact O-N 3.11Å
38	I	60.5	Low	60.9	Low	150 Å²	150	116.1 Å²	116.1	77%	0.769	74%	0.74	S	S	*	*			trans	-81	76	158.2	-45.5	158.6	0	0	0	103.5	S36	S36-I38 PolarHBondContact O-N 2.77Å
39	S	62.5	Low	59.5	Low	96 Å²	96	114.1 Å²	114.1	67%	0.671	74%	0.74	S	S	*	*			trans	-128.5	76.7	165.8	-168.1	0	0	0	0	106.1	A37 H41	A37-S39 PolarHBondContact O-N 3.08Å; A37-S39 VanDerWaalsContact O-N 3.11Å; S39-H41 PolarHBondContact O-N 3.11Å; S39-H41 VanDerWaalsContact O-N 3.08Å
40	A	56.3	Low	58.5	Low	110 Å²	110	118.5 Å²	118.5	91%	0.909	77%	0.766	S	S	*	*			trans	-68.8	90.3	153.5	0	0	0	0	0	106.2
41	H	53.3	Low	58.2	Low	231 Å²	231	124.8 Å²	124.8	100%	1.069	79%	0.79	S	S	*	*			trans	-137.3	0	164.1	-172.8	-57.7	0	0	0	107.9	S39	S39-H41 PolarHBondContact O-N 3.11Å; S39-H41 VanDerWaalsContact O-N 3.08Å

Retrieved 41 of 41 residues in 11.9 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).