Q99PI1_MOUSE Loading...

Downstream regulatory element antagonist T+ variant

AlphaFold DB , UniProt , Accession Q99PI1, Species MOUSE (Mus musculus, Mouse), Gene DREAM, Length 92 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M39.8Very low43Very low246 Ų246149 Ų149100%1.21285%0.849SS**  0123.10-83.1178.4-85.800108.5
2R43Very low43.2Very low258 Ų258142.9 Ų142.997%0.97483%0.83SS**  trans-126.7120.6169-81-176.4167.8175.9-3.6107
3Q48.3Very low43.8Very low186 Ų186141.9 Ų141.987%0.86983%0.834SS**  trans-96134.6-178.1-168.9178.5-5.100108.2
4L39.2Very low43.5Very low167 Ų167140.7 Ų140.787%0.87484%0.837SS**  trans-135.6155.7159.5-85.6176.7000108.3
5P38.4Very low43.4Very low110 Ų110135.6 Ų135.671%0.71483%0.825SS**PPolyproline II helix-96.2168.9-129.435.6-37.2000115.1G7P5-G7 PolarHBondContact O-N 3.36Å
6A55.3Low43Very low104 Ų104135.6 Ų135.686%0.8683%0.831SS**PPolyproline II helixtrans-54.2123.5175.100000112.2
7G36.6Very low43.1Very low65 Ų65139.6 Ų139.667%0.6783%0.834SS**PPolyproline II helixtrans-91.8144.916800000111.1P5P5-G7 PolarHBondContact O-N 3.36Å
8P40.1Very low43.5Very low118 Ų118137.1 Ų137.177%0.76683%0.831SS**PPolyproline II helixtrans-74.2148.4-163.831.3-36.4000113.7
9S39.9Very low43.6Very low100 Ų100133.3 Ų133.370%0.69982%0.822SS**SBendtrans-7.9139.6147.451.40000117.8
10S51.8Low43.4Very low118 Ų118138 Ų13883%0.82582%0.824SS**  trans18.1110.7145.5-1800000116.4
11L41Very low43.4Very low167 Ų167139 Ų13987%0.87483%0.825SS**  trans-131.5107.5157.3-109.2146.3000109
12A45.2Very low43.4Very low76 Ų76132.2 Ų132.263%0.62880%0.797SS**  trans-60.1145.7163.600000110.5
13C50.3Low43.3Very low130 Ų130125.8 Ų125.888%0.87879%0.786SS**  trans54.7123.4154.8-60.40000118.8
14S39.8Very low43.1Very low125 Ų125122.6 Ų122.687%0.87478%0.779SS**  trans-146.4115143.5-164.50000109.8
15G41.9Very low43.2Very low64 Ų64120.4 Ų120.466%0.6678%0.775SS**  trans-51.1141.1-171.500000113.5K17G15-K17 PolarHBondContact O-N 3.48Å
16C37Very low43.4Very low135 Ų135124.2 Ų124.291%0.91278%0.781SS**  trans-51.1112.5159-59.80000107A18C16-A18 PolarHBondContact O-N 3.31Å
17K45.2Very low42.6Very low204 Ų204123.9 Ų123.989%0.88777%0.772SS**  trans-54.5107.6179.3-71.9-169175.9-172.30108.4G15 G19G15-K17 PolarHBondContact O-N 3.48Å; K17-G19 PolarHBondContact O-N 3.41Å
18A50Low43Very low95 Ų95124.8 Ų124.879%0.78577%0.768SS**  trans-55131161.900000107.1C16 R20C16-A18 PolarHBondContact O-N 3.31Å; A18-R20 PolarHBondContact O-N 3.39Å
19G45.4Very low43.1Very low64 Ų64129.5 Ų129.566%0.6677%0.771SS**  trans-47.7134.4-179.100000111.2K17 L21K17-G19 PolarHBondContact O-N 3.41Å; G19-L21 PolarHBondContact O-N 3.49Å
20R40.8Very low43.2Very low227 Ų227132.4 Ų132.486%0.85778%0.778SS**  trans-36.5110.2173.2176.5179.5165.1-157.6-3.4111.4A18 V22A18-R20 PolarHBondContact O-N 3.39Å; R20-V22 HydrophobicContact CG-CG2 4.4Å; R20-V22 PolarHBondContact O-N 3.27Å
21L42.7Very low42.9Very low160 Ų160131.1 Ų131.184%0.83878%0.775SS**  trans-70.3112.5164.4-107.7119.2000107.8G19 T23G19-L21 PolarHBondContact O-N 3.49Å; L21-T23 PolarHBondContact O-N 3.37Å
22V40.2Very low42.9Very low103 Ų103132 Ų13262%0.62478%0.775SS**  trans-80.5106.1168.5176.80000106.8R20 V24R20-V22 HydrophobicContact CG-CG2 4.4Å; R20-V22 PolarHBondContact O-N 3.27Å; V22-V24 PolarHBondContact O-N 3.07Å
23T40.5Very low42.9Very low123 Ų123135.6 Ų135.676%0.75578%0.783SS**  trans-80.6114.9172.7-38.90000108.5L21L21-T23 PolarHBondContact O-N 3.37Å
24V44.3Very low42.4Very low119 Ų119136.2 Ų136.272%0.72177%0.773SS**PPolyproline II helixtrans-76.2133.4172.1-172.10000107.9V22 F26V22-V24 PolarHBondContact O-N 3.07Å; V24-F26 PolarHBondContact O-N 3.34Å
25P40.6Very low42.6Very low121 Ų121134.6 Ų134.679%0.78678%0.776SS**PPolyproline II helixtrans-67.1131-178.726.1-32.1000110.8S27P25-S27 PolarHBondContact O-N 2.96Å
26F43.9Very low42.6Very low190 Ų190135.2 Ų135.283%0.83377%0.77SS**PPolyproline II helixtrans-72118.8177.7-177.9-100.3000110.1V24V24-F26 PolarHBondContact O-N 3.34Å
27S37.7Very low43.1Very low97 Ų97140.7 Ų140.768%0.67877%0.772SS**  trans-95.1114.4166.7-179.10000108.2P25 R29P25-S27 PolarHBondContact O-N 2.96Å; S27-R29 VanDerWaalsContact C-N 3.25Å; S27-R29 PolarHBondContact O-N 2.91Å
28S45.6Very low43Very low85 Ų85138 Ų13859%0.59476%0.762SS**  trans-85.617.2-17565.70000114
29R40.3Very low42.6Very low216 Ų216137.4 Ų137.482%0.81577%0.766SS**THydrogen-bonded Turntrans-96.4-6.5-160.4-144.7170.8-172.91721.5116.6S27S27-R29 VanDerWaalsContact C-N 3.25Å; S27-R29 PolarHBondContact O-N 2.91Å
30D43.6Very low42.5Very low161 Ų161140.1 Ų140.186%0.86176%0.764SS**THydrogen-bonded Turntrans-102.78.2178.3-63.5-37.8000113.4
31A44.3Very low42.6Very low91 Ų91132.8 Ų132.875%0.75276%0.759SS**SBendtrans-89.92.3-174.700000114.8
32E42.7Very low42.5Very low187 Ų187136.2 Ų136.287%0.87476%0.761SS**SBendtrans-108.4-2.2-171.7-68.1-138.8111.300115.9
33D43.6Very low42.9Very low150 Ų150138.3 Ų138.380%0.80276%0.764SS**SBendtrans-139.858.5-177.2-154.935000114.4
34Q41.3Very low42.9Very low144 Ų144137 Ų13767%0.67376%0.758SS**  trans-155.985.6151.4-115.2178.671.500112S36Q34-S36 PolarHBondContact O-N 2.69Å
35G42.8Very low42.8Very low90 Ų90138 Ų13893%0.92877%0.767SS**  trans-66.279.3157.600000110.3
36S43Very low43.1Very low78 Ų78136 Ų13655%0.54577%0.768SS.*SBendtrans-176.296.2159.5173.50000108.9Q34 E38Q34-S36 PolarHBondContact O-N 2.69Å; S36-E38 PolarHBondContact O-N 2.9Å
37R46.8Very low43.1Very low249 Ų249137.1 Ų137.194%0.9477%0.767SS**SBendtrans34.427.7144.6-142.1-173.2-173.7-152.10.8121
38E42.9Very low43.5Very low147 Ų147138 Ų13869%0.68777%0.773SS**  trans-131.888.4174.7-86.9159-171.100108S36 I40S36-E38 PolarHBondContact O-N 2.9Å; E38-I40 PolarHBondContact O-N 2.96Å
39G42.5Very low43.6Very low83 Ų83144.5 Ų144.586%0.85678%0.784SS**  trans-63.4103.1168.300000107.9G41G39-G41 PolarHBondContact O-N 3.2Å
40I41.7Very low43.8Very low122 Ų122137.9 Ų137.963%0.62678%0.776SS**  trans-68.685.6174.7-53.2177.5000107.4E38 W42E38-I40 PolarHBondContact O-N 2.96Å; I40-W42 PolarHBondContact O-N 2.79Å
41G44.4Very low43.8Very low73 Ų73136.6 Ų136.675%0.75377%0.765SS**  trans-74.210017200000109.3G39G39-G41 PolarHBondContact O-N 3.2Å
42W40.1Very low43.7Very low231 Ų231136.9 Ų136.988%0.87576%0.757SS**  trans-77.3125.3166.2-71.997.7000109.5I40I40-W42 PolarHBondContact O-N 2.79Å
43Q47.7Very low43.8Very low147 Ų147133.9 Ų133.969%0.68775%0.752SS**  trans-126.1151170.4-108-161.9-8.900112.4
44P40.7Very low43.6Very low97 Ų97135.1 Ų135.163%0.6375%0.753SS**  trans-70155.3-172.529.2-33.6000112.8G46P44-G46 PolarHBondContact O-N 3.37Å
45P42.1Very low43.8Very low139 Ų139134.7 Ų134.790%0.90375%0.751SS**THydrogen-bonded Turntrans-64.2129.1-175.725.1-32.4000111.3
46G46.7Very low43.7Very low80 Ų80139.3 Ų139.383%0.82575%0.748SS**THydrogen-bonded Turntrans122.89.6171.300000117.1P44P44-G46 PolarHBondContact O-N 3.37Å
47R45Very low44.1Very low213 Ų213138 Ų13880%0.80475%0.748SS**  trans-125.5139.2172.4-71.9-174.1177.9-117.5-0.1111.9
48S45.3Very low44.1Very low114 Ų114135.8 Ų135.880%0.79775%0.745SS**  trans-68147.8175.418.20000111.4A50S48-A50 PolarHBondContact O-N 3.03Å; S48-A50 VanDerWaalsContact O-N 3.12Å
49W48.9Very low44.1Very low222 Ų222136 Ų13684%0.84175%0.745SS**  trans-48.7115178.9-83.923.1000111.5H51W49-H51 AromaticContact CE3-CE1 3.22Å; W49-H51 AromaticContact CE3-NE2 3.18Å; W49-H51 AromaticContact CZ3-CE1 3.33Å; W49-H51 WeakPolarHBondContact CZ3-CE1 3.33Å; W49-H51 AromaticContact CZ3-NE2 3.59Å
50A44.8Very low44.2Very low78 Ų78139.3 Ų139.365%0.64574%0.738SS**  trans-95.498162.800000107.4S48 T52S48-A50 PolarHBondContact O-N 3.03Å; S48-A50 VanDerWaalsContact O-N 3.12Å; A50-T52 PolarHBondContact O-N 3.12Å
51H41.7Very low44.4Very low133 Ų133139.1 Ų139.162%0.61674%0.743SS**  trans-69.496.8165.1-71.1-66.8000108.5W49 T53W49-H51 AromaticContact CE3-CE1 3.22Å; W49-H51 AromaticContact CE3-NE2 3.18Å; W49-H51 AromaticContact CZ3-CE1 3.33Å; W49-H51 WeakPolarHBondContact CZ3-CE1 3.33Å; W49-H51 AromaticContact CZ3-NE2 3.59Å; H51-T53 PolarHBondContact O-N 3.22Å
52T42.2Very low44.7Very low98 Ų98139.1 Ų139.160%0.60174%0.736SS**  trans-83.288166.545.60000108.7A50 A62A50-T52 PolarHBondContact O-N 3.12Å; T52-A62 HydrophobicContact CG2-CB 4Å
53T46.8Very low44.8Very low123 Ų123137.4 Ų137.476%0.75573%0.734SS**  trans-132.792165.347.40000109.4H51H51-T53 PolarHBondContact O-N 3.22Å
54E38.9Very low44.8Very low176 Ų176134.5 Ų134.582%0.82274%0.735SS**  -178.8121.3115.6-130.1172160.100107.8E56E54-E56 PolarHBondContact O-N 3.39Å
55Q45.3Very low45.1Very low136 Ų136135.6 Ų135.664%0.63674%0.741SS**  trans-89.8102.2174.2-177.9-177.54.200108G57 Q60Q55-G57 PolarHBondContact NE2-O 3.38Å; Q55-G57 WeakPolarHBondContact CG-O 3.44Å; Q55-Q60 HydrophobicContact CG-CG 4.27Å
56E41.3Very low45.4Very low186 Ų186135.5 Ų135.587%0.86974%0.737SS**  trans-100.699.5168.2-144.8-177.5178.300109E54E54-E56 PolarHBondContact O-N 3.39Å
57G50.2Low45.6Very low52 Ų52139.1 Ų139.154%0.53673%0.732SS.*SBendtrans82.1-168.6179.100000116.4Q55 H59Q55-G57 PolarHBondContact NE2-O 3.38Å; Q55-G57 WeakPolarHBondContact CG-O 3.44Å; G57-H59 PolarHBondContact O-N 3.15Å; G57-H59 VanDerWaalsContact O-N 3.15Å
58K46.2Very low45.9Very low201 Ų201134.3 Ų134.387%0.87473%0.729SS**SBendtrans-69-4.8-175.5-73.7-173.1178.9-178.20114.7
59H44.8Very low46.8Very low152 Ų152133.3 Ų133.370%0.70472%0.719SS**SBendtrans-124.9118.2-178.4-65.391.6000109.1G57 V61G57-H59 PolarHBondContact O-N 3.15Å; G57-H59 VanDerWaalsContact O-N 3.15Å; H59-V61 PolarHBondContact O-N 3.06Å
60Q44.1Very low47.1Very low152 Ų152124.9 Ų124.971%0.7170%0.702SS**  trans-74.9116.9174.6-69.5-178.96.500109Q55Q55-Q60 HydrophobicContact CG-CG 4.27Å
61V45.3Very low47.5Very low119 Ų119127.5 Ų127.572%0.72171%0.712SS**  trans-105.8102.5170.3-175.90000107.5H59 K63H59-V61 PolarHBondContact O-N 3.06Å; V61-K63 PolarHBondContact O-N 3.14Å; V61-K63 VanDerWaalsContact O-N 3.16Å
62A50.5Low48.1Very low73 Ų73128.4 Ų128.460%0.60372%0.721SS**  trans-72.9105.4175.800000109.6T52 A64T52-A62 HydrophobicContact CG2-CB 4Å; A62-A64 PolarHBondContact O-N 3.09Å
63K41.5Very low48.8Very low194 Ų194126 Ų12684%0.84371%0.712SS**  trans-83.599.3172.5-162.4178.2-175.4-179.50108.8V61V61-K63 PolarHBondContact O-N 3.14Å; V61-K63 VanDerWaalsContact O-N 3.16Å
64A49Very low48.9Very low86 Ų86127.7 Ų127.771%0.71172%0.715SS**  trans-82.6115.4177.900000110.7A62A62-A64 PolarHBondContact O-N 3.09Å
65T45.8Very low49.8Very low121 Ų121125.3 Ų125.374%0.74271%0.707SS**PPolyproline II helixtrans-85.7117.3162.922.40000109.3
66V50.3Low50.1Low136 Ų136126.3 Ų126.382%0.82472%0.717SS**PPolyproline II helixtrans-89.3120.8179.5-179.10000108.9
67H49.2Very low50.7Low156 Ų156124.7 Ų124.772%0.72271%0.714SS**PPolyproline II helixtrans-92.2140.9170.2-65.9-80.8000110.2
68P52.4Low50.8Low113 Ų113130.6 Ų130.673%0.73473%0.727SS**PPolyproline II helixtrans-66.5147.5176.928.1-33.1000110.6
69P64.8Low50.8Low92 Ų92126.6 Ų126.660%0.59772%0.719SS**PPolyproline II helixtrans-63.1142.9177.625-31.6000111.4A73P69-A73 HydrophobicContact CB-CB 3.54Å
70G55.1Low50.9Low46 Ų46125.8 Ų125.847%0.47472%0.72SS.*PPolyproline II helixtrans-69.1169.5175.700000113.1D72 A73G70-D72 PolarHBondContact O-N 3.16Å; G70-D72 VanDerWaalsContact O-N 3.14Å; G70-A73 WeakPolarHBondContact O-CB 3.21Å; G70-A73 PolarHBondContact O-N 3.27Å
71P52.3Low51.3Low132 Ų132124 Ų12486%0.85772%0.722SS**THydrogen-bonded Turntrans-60.6-28.2-171.823.7-33.6000114
72D54.1Low51.4Low152 Ų152124.8 Ų124.881%0.81373%0.727SS**THydrogen-bonded Turntrans-94.57.8-179.3-53.9-51.4000113.4G70 L74G70-D72 PolarHBondContact O-N 3.16Å; G70-D72 VanDerWaalsContact O-N 3.14Å; D72-L74 PolarHBondContact O-N 3.48Å
73A57.1Low51.2Low48 Ų48129.8 Ų129.840%0.39774%0.737SS.*  trans-74101.917900000110.5P69 G70 L75P69-A73 HydrophobicContact CB-CB 3.54Å; G70-A73 WeakPolarHBondContact O-CB 3.21Å; G70-A73 PolarHBondContact O-N 3.27Å; A73-L75 PolarHBondContact O-N 2.72Å
74L48.1Very low51.2Low159 Ų159126.6 Ų126.683%0.83274%0.738SS**  trans-69.8109.4168.3-65.3174.4000109.5D72 L76D72-L74 PolarHBondContact O-N 3.48Å; L74-L76 VanDerWaalsContact O-N 3.14Å; L74-L76 PolarHBondContact O-N 3.4Å
75L57.8Low51.2Low125 Ų125128.2 Ų128.265%0.65474%0.743SS**  trans-72.6101.7174.2-66.7170.7000109.6A73 N77A73-L75 PolarHBondContact O-N 2.72Å; L75-N77 PolarHBondContact O-N 3.23Å; L75-N77 VanDerWaalsContact O-N 3.09Å
76L53.1Low51.1Low158 Ų158128.2 Ų128.283%0.82775%0.745SS**  trans-71.15.8179.1-81158.7000114.9L74L74-L76 VanDerWaalsContact O-N 3.14Å; L74-L76 PolarHBondContact O-N 3.4Å
77N53.5Low50.9Low152 Ų152127.6 Ų127.681%0.81374%0.742SS**  trans-116.240.5-175.2-72.1-26.4000113.6L75 V79L75-N77 PolarHBondContact O-N 3.23Å; L75-N77 VanDerWaalsContact O-N 3.09Å; N77-V79 VanDerWaalsContact C-N 3.34Å
78Q51.5Low50.6Low176 Ų176131.8 Ų131.882%0.82275%0.751SS**  trans-104.854.3156.4-65.2-1637300109.3D80Q78-D80 PolarHBondContact O-N 3.03Å
79V46.5Very low50.3Low116 Ų116133.7 Ų133.770%0.70376%0.755SS**  trans-71.5108.2150.6-174.80000103.7N77N77-V79 VanDerWaalsContact C-N 3.34Å
80D48.2Very low49.1Very low135 Ų135140.6 Ų140.672%0.72277%0.769SS**  trans-40.5130.2169.7-111.7-36.7000107.9Q78 V82Q78-D80 PolarHBondContact O-N 3.03Å; D80-V82 VanDerWaalsContact C-N 3.26Å; D80-V82 PolarHBondContact O-N 3.14Å
81P51.1Low48.5Very low116 Ų116147.2 Ų147.275%0.75379%0.787SS**  trans-57.6103.2169.324-29.9000105.8Q83P81-Q83 PolarHBondContact O-N 3.31Å
82V48.9Very low48.1Very low134 Ų134153.8 Ų153.881%0.81281%0.807SS**  trans-51.7112.9176.2175.30000105D80 C84D80-V82 VanDerWaalsContact C-N 3.26Å; D80-V82 PolarHBondContact O-N 3.14Å; V82-C84 PolarHBondContact O-N 3.18Å
83Q45.5Very low47.8Very low178 Ų178153.9 Ų153.983%0.83281%0.806SS**  trans-36.1131.5-174.9-83.9163.5-31.300111P81 C85P81-Q83 PolarHBondContact O-N 3.31Å; Q83-C85 PolarHBondContact O-N 2.84Å
84C42.2Very low47.3Very low127 Ų127159.5 Ų159.586%0.85883%0.828SS**SBendtrans-29.2126.3154.4-77.70000109.9V82V82-C84 PolarHBondContact O-N 3.18Å
85C48.8Very low47.2Very low121 Ų121159.5 Ų159.582%0.81883%0.828SS**SBendtrans-37.6138.3179.7-66.40000112.2Q83 T87Q83-C85 PolarHBondContact O-N 2.84Å; C85-T87 PolarHBondContact O-N 3.35Å
86P42.7Very low46.6Very low121 Ų121161.5 Ų161.579%0.78684%0.838SS**  trans-59.4132.5-170.323.4-33.3000111.2R88P86-R88 PolarHBondContact O-N 2.75Å; P86-R88 VanDerWaalsContact O-N 3.08Å
87T46.1Very low46.2Very low123 Ų123161.8 Ų161.876%0.75584%0.839SS**  trans-36115.3157.1-47.30000108.5C85 L89C85-T87 PolarHBondContact O-N 3.35Å; T87-L89 PolarHBondContact O-N 3.08Å
88R44Very low45.7Very low243 Ų243162.4 Ų162.492%0.91784%0.84SS**  trans-66.981.5169.3-72.1-167.7-169.6-151.34.4108.2P86 R90P86-R88 PolarHBondContact O-N 2.75Å; P86-R88 VanDerWaalsContact O-N 3.08Å; R88-R90 PolarHBondContact O-N 3.18Å
89L46.2Very low45.3Very low154 Ų154161.4 Ų161.481%0.80684%0.842SS**  trans-76.187.5151.7-87.6165.3000106.8T87T87-L89 PolarHBondContact O-N 3.08Å
90R39Very low45.2Very low237 Ų237164.9 Ų164.989%0.89485%0.852SS**  trans-124.1112.5146-78.5-145.6176.4-164.51108.7R88 Q92R88-R90 PolarHBondContact O-N 3.18Å; R90-Q92 PolarHBondContact O-N 3.43Å
91Q42.6Very low44.9Very low185 Ų185167.4 Ų167.486%0.86486%0.863SS**  trans-47.1123.1156.3-63.3176-7.400109.2
92Q42.2Very low44.4Very low270 Ų270172.1 Ų172.1100%1.26287%0.873SS**  trans-166.10133.9-101.8176.315.200107.9R90R90-Q92 PolarHBondContact O-N 3.43Å

Retrieved 92 of 92 residues in 17.7 ms (Link to these results)