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Thiamine transporter 2

High-affinity transporter for the intake of thiamine^1,2,3. Unlike the human ortholog, lacks H(+)-dependent pyridoxine transport activity due to an absence of seven critical amino-acids required for pyridoxine transport^4,5.

AlphaFold DB , UniProt , Accession Q99PL8, Species MOUSE (Mus musculus, Mouse), Gene Slc19a3, Length 488 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	37.9	Very low	43.5	Very low	234 Å²	234	134.6 Å²	134.6	100%	1.153	77%	0.77	S	S	*	*				0	87.3	0	-87.5	179	167.6	0	0	105.5	S3	M1-S3 VanDerWaalsContact C-N 3.32Å; M1-S3 PolarHBondContact O-N 2.96Å
2	D	36.1	Very low	46.3	Very low	157 Å²	157	128.8 Å²	128.8	84%	0.84	74%	0.743	S	S	*	*			trans	-75.3	91.3	-179.1	-65.5	-26	0	0	0	107.9	S4	D2-S4 PolarHBondContact O-N 2.84Å
3	S	38.9	Very low	49.3	Very low	108 Å²	108	121.5 Å²	121.5	76%	0.755	70%	0.696	S	S	*	*			trans	-64.6	89.7	162.6	51.8	0	0	0	0	106.6	M1 C5	M1-S3 VanDerWaalsContact C-N 3.32Å; M1-S3 PolarHBondContact O-N 2.96Å; S3-C5 PolarHBondContact O-N 3.46Å
4	S	41.5	Very low	52.2	Low	102 Å²	102	116.6 Å²	116.6	71%	0.713	67%	0.669	S	S	*	*			trans	-49.2	109.7	172.4	-60.2	0	0	0	0	108.8	D2 R6	D2-S4 PolarHBondContact O-N 2.84Å; S4-R6 PolarHBondContact O-N 3.36Å
5	C	40.1	Very low	54.8	Low	125 Å²	125	117.2 Å²	117.2	85%	0.845	66%	0.657	S	S	*	*			trans	-58.7	87.3	160.8	-75.8	0	0	0	0	107.1	S3 T7	S3-C5 PolarHBondContact O-N 3.46Å; C5-T7 VanDerWaalsContact C-N 3.33Å; C5-T7 PolarHBondContact O-N 2.93Å
6	R	36.2	Very low	57.1	Low	227 Å²	227	110.3 Å²	110.3	86%	0.857	62%	0.619	S	S	*	*			trans	-60.2	104.5	165.7	-78.2	-176.7	-177.3	178.4	1.2	105.5	S4 P8	S4-R6 PolarHBondContact O-N 3.36Å; R6-P8 VanDerWaalsContact O-N 3.15Å
7	T	39.8	Very low	59.2	Low	125 Å²	125	104.3 Å²	104.3	77%	0.767	59%	0.586	S	S	*	*			trans	-45.2	123.4	156.1	40	0	0	0	0	106.1	C5 P9	C5-T7 VanDerWaalsContact C-N 3.33Å; C5-T7 PolarHBondContact O-N 2.93Å; T7-P9 VanDerWaalsContact O-N 3.17Å
8	P	44.3	Very low	61.2	Low	96 Å²	96	102.6 Å²	102.6	62%	0.623	58%	0.578	S	S	*	*			trans	-53.5	131.1	178.2	19	-28.2	0	0	0	106.9	R6 S10	R6-P8 VanDerWaalsContact O-N 3.15Å; P8-S10 PolarHBondContact O-N 3.45Å
9	P	46	Very low	63	Low	98 Å²	98	98.2 Å²	98.2	64%	0.636	55%	0.553	S	S	*	*			trans	-51.6	139.4	-173.1	18.4	-30.4	0	0	0	109.1	T7 N11 S12	T7-P9 VanDerWaalsContact O-N 3.17Å; P9-N11 PolarHBondContact O-N 2.76Å; P9-S12 VanDerWaalsContact O-CB 3.31Å; P9-S12 WeakPolarHBondContact O-CB 3.15Å; P9-S12 PolarHBondContact O-N 3.49Å; P9-S12 PolarHBondContact O-OG 3.47Å
10	S	55.6	Low	64.5	Low	98 Å²	98	93.5 Å²	93.5	69%	0.685	53%	0.526	S	S	*	.	T	Hydrogen-bonded Turn	trans	-49.8	-20.5	-171.5	66.5	0	0	0	0	114.9	P8 W13	P8-S10 PolarHBondContact O-N 3.45Å; S10-W13 PolarHBondContact O-NE1 2.91Å
11	N	61.8	Low	66.1	Low	111 Å²	111	90.1 Å²	90.1	59%	0.594	51%	0.508	S	S	*	.	T	Hydrogen-bonded Turn	trans	-100.5	13.1	-179.7	-62.9	-15.2	0	0	0	113.9	P9 W13 V14	P9-N11 PolarHBondContact O-N 2.76Å; N11-W13 PolarHBondContact O-N 3.08Å; N11-V14 HydrophobicContact CB-CG2 4.08Å; N11-V14 WeakPolarHBondContact O-CB 3.43Å; N11-V14 PolarHBondContact O-N 3.15Å
12	S	77.3	Confident	68.9	Low	64 Å²	64	81.9 Å²	81.9	45%	0.448	47%	0.468	S	S	.	.	T	Hydrogen-bonded Turn	trans	-62.1	-25.8	-177.1	66.8	0	0	0	0	113.4	P9 P16	P9-S12 VanDerWaalsContact O-CB 3.31Å; P9-S12 WeakPolarHBondContact O-CB 3.15Å; P9-S12 PolarHBondContact O-N 3.49Å; P9-S12 PolarHBondContact O-OG 3.47Å; S12-P16 WeakPolarHBondContact O-CD 3.26Å; S12-P16 WeakPolarHBondContact O-CG 3.46Å
13	W	85.3	Confident	71.8	Confident	34 Å²	34	74.5 Å²	74.5	13%	0.129	43%	0.429	C	S	.	.	T	Hydrogen-bonded Turn	trans	-81	-19.4	177	67.2	-91.7	0	0	0	113.3	S10 N11 P16 T17 V132 H136 K139 V140	S10-W13 PolarHBondContact O-NE1 2.91Å; N11-W13 PolarHBondContact O-N 3.08Å; W13-P16 WeakPolarHBondContact O-CD 3.41Å; W13-T17 HydrophobicContact CZ3-CG2 4.41Å; W13-T17 VanDerWaalsContact O-CB 3.25Å; W13-T17 WeakPolarHBondContact O-CB 3.41Å; W13-T17 PolarHBondContact O-N 3.05Å; W13-T17 VanDerWaalsContact O-N 3.13Å; W13-T17 PolarHBondContact O-OG1 3.29Å; W13-V132 HydrophobicContact CB-CG1 4.3Å; W13-V132 HydrophobicContact CB-CG2 4.39Å; W13-H136 AromaticContact CD1-CE1 3.93Å; W13-H136 AromaticContact CD1-NE2 3.82Å; W13-H136 AromaticContact CE2-CD2 3.48Å; W13-H136 VanDerWaalsContact CE2-CD2 3.48Å; W13-H136 AromaticContact CE2-NE2 3.74Å; W13-H136 AromaticContact CZ2-CD2 3.78Å; W13-H136 AromaticContact NE1-CD2 3.47Å; W13-H136 PolarHBondContact NE1-CD2 3.27Å; W13-H136 AromaticContact NE1-CE1 3.8Å; W13-H136 AromaticContact NE1-NE2 3.24Å; W13-H136 PolarHBondContact NE1-NE2 3.02Å; W13-K139 HydrophobicContact CH2-CD 4.33Å; W13-V140 HydrophobicContact CE3-CG2 3.58Å; W13-V140 HydrophobicContact CZ3-CG2 3.73Å
14	V	90.1	Very high	74.5	Confident	54 Å²	54	69.3 Å²	69.3	33%	0.327	39%	0.393	S	S	.	.	H	α-helix	trans	-68.2	-49.1	-174.6	179.3	0	0	0	0	110.9	N11 T17 V18	N11-V14 HydrophobicContact CB-CG2 4.08Å; N11-V14 WeakPolarHBondContact O-CB 3.43Å; N11-V14 PolarHBondContact O-N 3.15Å; V14-T17 PolarHBondContact O-N 3.08Å; V14-V18 HydrophobicContact CG1-CG2 4.12Å; V14-V18 VanDerWaalsContact O-CG2 3.32Å; V14-V18 WeakPolarHBondContact O-CG2 3.23Å; V14-V18 PolarHBondContact O-N 2.75Å
15	Y	91.1	Very high	77.2	Confident	125 Å²	125	67 Å²	67	49%	0.49	37%	0.37	S	S	.	.	H	α-helix	trans	-58.9	-53.4	-179.8	170.7	-90.9	0	0	0	112.9	T17 V18 I19 F190	Y15-T17 VanDerWaalsContact C-N 3.25Å; Y15-T17 PolarHBondContact O-N 3.5Å; Y15-V18 PolarHBondContact O-N 3.38Å; Y15-I19 HydrophobicContact CD2-CG1 4.32Å; Y15-I19 HydrophobicContact CE1-CG1 4.18Å; Y15-I19 HydrophobicContact CE2-CD1 4.13Å; Y15-I19 HydrophobicContact CE2-CG1 3.88Å; Y15-I19 WeakPolarHBondContact O-CG1 3.44Å; Y15-I19 PolarHBondContact O-N 3.43Å; Y15-I19 VanDerWaalsContact O-N 3.1Å; Y15-F190 PolarHBondContact OH-O 2.95Å
16	P	90.9	Very high	80	Confident	7 Å²	7	63.7 Å²	63.7	5%	0.045	34%	0.342	C	S	.	.	H	α-helix	trans	-55.8	-41.6	175.1	-18.6	25.4	0	0	0	112.3	S12 W13 I19 L20 M131 P192	S12-P16 WeakPolarHBondContact O-CD 3.26Å; S12-P16 WeakPolarHBondContact O-CG 3.46Å; W13-P16 WeakPolarHBondContact O-CD 3.41Å; P16-I19 PolarHBondContact O-N 3.43Å; P16-L20 WeakPolarHBondContact O-CB 3.31Å; P16-L20 PolarHBondContact O-N 2.67Å; P16-M131 HydrophobicContact CB-CE 4.11Å; P16-M131 HydrophobicContact CG-CE 3.87Å; P16-P192 HydrophobicContact CB-CG 3.86Å; P16-P192 HydrophobicContact CG-CG 3.91Å
17	T	92.9	Very high	82.8	Confident	8 Å²	8	53.2 Å²	53.2	5%	0.049	30%	0.303	C	S	.	.	H	α-helix	trans	-64.3	-44.6	-179.9	-61	0	0	0	0	112	W13 V14 Y15 L20 C21 V140 Y143	W13-T17 HydrophobicContact CZ3-CG2 4.41Å; W13-T17 VanDerWaalsContact O-CB 3.25Å; W13-T17 WeakPolarHBondContact O-CB 3.41Å; W13-T17 PolarHBondContact O-N 3.05Å; W13-T17 VanDerWaalsContact O-N 3.13Å; W13-T17 PolarHBondContact O-OG1 3.29Å; V14-T17 PolarHBondContact O-N 3.08Å; Y15-T17 VanDerWaalsContact C-N 3.25Å; Y15-T17 PolarHBondContact O-N 3.5Å; T17-L20 PolarHBondContact O-N 3.23Å; T17-C21 WeakPolarHBondContact O-CB 3.32Å; T17-C21 PolarHBondContact O-N 2.98Å; T17-C21 PolarHBondContact O-SG 3.34Å; T17-V140 HydrophobicContact CG2-CG1 3.78Å; T17-V140 HydrophobicContact CG2-CG2 4.26Å; T17-Y143 HydrophobicContact CG2-CD2 4.4Å
18	V	95.1	Very high	85.4	Confident	74 Å²	74	48.6 Å²	48.6	45%	0.448	27%	0.273	S	S	.	.	H	α-helix	trans	-62.5	-47.9	178.9	169.7	0	0	0	0	110.7	V14 Y15 L20 C21 L22	V14-V18 HydrophobicContact CG1-CG2 4.12Å; V14-V18 VanDerWaalsContact O-CG2 3.32Å; V14-V18 WeakPolarHBondContact O-CG2 3.23Å; V14-V18 PolarHBondContact O-N 2.75Å; Y15-V18 PolarHBondContact O-N 3.38Å; V18-L20 VanDerWaalsContact C-N 3.31Å; V18-L20 PolarHBondContact O-N 3.02Å; V18-C21 PolarHBondContact O-N 3.15Å; V18-L22 HydrophobicContact CG1-CD1 4.01Å; V18-L22 WeakPolarHBondContact O-CG 3.31Å; V18-L22 PolarHBondContact O-N 3.17Å
19	I	95.5	Very high	87.9	Confident	19 Å²	19	45.3 Å²	45.3	10%	0.097	25%	0.249	C	C	.	.	H	α-helix	trans	-63.6	-39.9	178.3	-59	-58.3	0	0	0	110.9	Y15 P16 L22 F23 F187 F190 L191	Y15-I19 HydrophobicContact CD2-CG1 4.32Å; Y15-I19 HydrophobicContact CE1-CG1 4.18Å; Y15-I19 HydrophobicContact CE2-CD1 4.13Å; Y15-I19 HydrophobicContact CE2-CG1 3.88Å; Y15-I19 WeakPolarHBondContact O-CG1 3.44Å; Y15-I19 PolarHBondContact O-N 3.43Å; Y15-I19 VanDerWaalsContact O-N 3.1Å; P16-I19 PolarHBondContact O-N 3.43Å; I19-L22 PolarHBondContact O-N 3.48Å; I19-F23 WeakPolarHBondContact O-CB 3.09Å; I19-F23 PolarHBondContact O-N 3.36Å; I19-F187 HydrophobicContact CD1-CD1 4.4Å; I19-F187 HydrophobicContact CG2-CB 4.45Å; I19-F187 WeakPolarHBondContact CG2-O 3.39Å; I19-F190 HydrophobicContact CG2-CB 4.24Å; I19-L191 HydrophobicContact CB-CD2 4.14Å; I19-L191 HydrophobicContact CG2-CD2 3.69Å; I19-L191 HydrophobicContact CG2-CG 3.96Å
20	L	94.5	Very high	90.2	Very high	4 Å²	4	41.4 Å²	41.4	2%	0.021	22%	0.221	C	C	.	.	H	α-helix	trans	-66.2	-40.9	177.2	-170.7	67.1	0	0	0	112.2	P16 T17 V18 F23 G24 Y124 Y127 I128 L191	P16-L20 WeakPolarHBondContact O-CB 3.31Å; P16-L20 PolarHBondContact O-N 2.67Å; T17-L20 PolarHBondContact O-N 3.23Å; V18-L20 VanDerWaalsContact C-N 3.31Å; V18-L20 PolarHBondContact O-N 3.02Å; L20-F23 WeakPolarHBondContact O-CB 3.41Å; L20-F23 PolarHBondContact O-N 3.17Å; L20-G24 PolarHBondContact O-N 3.25Å; L20-Y124 HydrophobicContact CD1-CD2 3.59Å; L20-Y124 HydrophobicContact CD1-CE2 3.49Å; L20-Y124 VanDerWaalsContact CD1-CE2 3.49Å; L20-Y124 HydrophobicContact CG-CD2 4.23Å; L20-Y124 HydrophobicContact CG-CE2 3.65Å; L20-Y124 WeakPolarHBondContact O-CE2 3.21Å; L20-Y127 HydrophobicContact CD1-CD1 3.73Å; L20-Y127 HydrophobicContact CD1-CE1 4.12Å; L20-Y127 HydrophobicContact CD1-CG 4.45Å; L20-Y127 HydrophobicContact CD2-CD1 3.73Å; L20-Y127 HydrophobicContact CD2-CE1 4.24Å; L20-Y127 HydrophobicContact CG-CD1 4.31Å; L20-I128 HydrophobicContact CD2-CG1 3.56Å; L20-L191 HydrophobicContact CB-CD2 4.11Å; L20-L191 HydrophobicContact CD1-CD1 4.4Å; L20-L191 HydrophobicContact CD1-CD2 4.12Å
21	C	96.6	Very high	92.1	Very high	22 Å²	22	36.7 Å²	36.7	15%	0.149	19%	0.189	C	C	.	.	H	α-helix	trans	-65.8	-39	174.8	-72.8	0	0	0	0	112.1	T17 V18 G24 F25 I147	T17-C21 WeakPolarHBondContact O-CB 3.32Å; T17-C21 PolarHBondContact O-N 2.98Å; T17-C21 PolarHBondContact O-SG 3.34Å; V18-C21 PolarHBondContact O-N 3.15Å; C21-G24 PolarHBondContact O-N 3.12Å; C21-F25 WeakPolarHBondContact O-CB 3.37Å; C21-F25 PolarHBondContact O-N 3.08Å; C21-I147 HydrophobicContact CB-CG2 4.15Å
22	L	97.4	Very high	93.8	Very high	61 Å²	61	31.4 Å²	31.4	32%	0.319	16%	0.161	S	C	.	.	H	α-helix	trans	-63.9	-46.7	174.1	-72	168	0	0	0	110.9	V18 I19 G24 F25 F26 F187	V18-L22 HydrophobicContact CG1-CD1 4.01Å; V18-L22 WeakPolarHBondContact O-CG 3.31Å; V18-L22 PolarHBondContact O-N 3.17Å; I19-L22 PolarHBondContact O-N 3.48Å; L22-G24 PolarHBondContact O-N 2.79Å; L22-F25 PolarHBondContact O-N 3.19Å; L22-F26 HydrophobicContact CD2-CE2 4.44Å; L22-F26 WeakPolarHBondContact O-CD2 3.48Å; L22-F26 PolarHBondContact O-N 3.03Å; L22-F187 HydrophobicContact CB-CD1 3.98Å; L22-F187 HydrophobicContact CB-CD2 4.09Å; L22-F187 HydrophobicContact CB-CE1 4.05Å; L22-F187 HydrophobicContact CB-CE2 4.15Å; L22-F187 HydrophobicContact CB-CG 4.01Å; L22-F187 HydrophobicContact CB-CZ 4.13Å; L22-F187 HydrophobicContact CD1-CD1 4.09Å; L22-F187 HydrophobicContact CD1-CE1 3.55Å; L22-F187 HydrophobicContact CD1-CZ 3.91Å; L22-F187 HydrophobicContact CD2-CZ 4.48Å; L22-F187 HydrophobicContact CG-CE1 4.35Å; L22-F187 HydrophobicContact CG-CZ 4.4Å
23	F	96.9	Very high	94.5	Very high	2 Å²	2	30.1 Å²	30.1	1%	0.009	15%	0.147	C	C	.	.	H	α-helix	trans	-53.8	-52.4	171.6	170.6	-86.7	0	0	0	111.2	I19 L20 F25 F26 S27 I84 V88 Y124 A184 F187	I19-F23 WeakPolarHBondContact O-CB 3.09Å; I19-F23 PolarHBondContact O-N 3.36Å; L20-F23 WeakPolarHBondContact O-CB 3.41Å; L20-F23 PolarHBondContact O-N 3.17Å; F23-F25 VanDerWaalsContact C-N 3.32Å; F23-F25 PolarHBondContact O-N 3.49Å; F23-F26 PolarHBondContact O-N 3.43Å; F23-S27 VanDerWaalsContact O-CB 3.23Å; F23-S27 WeakPolarHBondContact O-CB 3.44Å; F23-S27 PolarHBondContact O-N 3.36Å; F23-S27 PolarHBondContact O-OG 2.72Å; F23-S27 VanDerWaalsContact O-OG 3.1Å; F23-I84 HydrophobicContact CD2-CG2 4.15Å; F23-I84 HydrophobicContact CE1-CG2 3.96Å; F23-I84 HydrophobicContact CE2-CG2 3.48Å; F23-I84 VanDerWaalsContact CE2-CG2 3.48Å; F23-I84 HydrophobicContact CZ-CG2 3.41Å; F23-I84 VanDerWaalsContact CZ-CG2 3.41Å; F23-V88 HydrophobicContact CE2-CG2 3.4Å; F23-V88 HydrophobicContact CZ-CG2 3.79Å; F23-Y124 AromaticContact CD1-CD2 3.54Å; F23-Y124 HydrophobicContact CD1-CD2 3.54Å; F23-Y124 AromaticContact CD1-CE2 3.65Å; F23-Y124 HydrophobicContact CD1-CE2 3.65Å; F23-Y124 AromaticContact CE1-CD2 3.58Å; F23-Y124 HydrophobicContact CE1-CD2 3.58Å; F23-Y124 HydrophobicContact CE1-CE2 4.14Å; F23-Y124 HydrophobicContact CE1-CG 4.37Å; F23-A184 HydrophobicContact CD2-CB 4.28Å; F23-A184 WeakPolarHBondContact CD2-O 2.88Å; F23-A184 HydrophobicContact CE2-CB 4.44Å; F23-F187 HydrophobicContact CB-CB 4.23Å
24	G	96.1	Very high	95	Very high	0 Å²	0	28.6 Å²	28.6	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-63.9	-34.6	-177.9	0	0	0	0	0	113.3	L20 C21 L22 S27 M28	L20-G24 PolarHBondContact O-N 3.25Å; C21-G24 PolarHBondContact O-N 3.12Å; L22-G24 PolarHBondContact O-N 2.79Å; G24-S27 WeakPolarHBondContact CA-OG 3.3Å; G24-S27 PolarHBondContact O-OG 2.93Å; G24-M28 VanDerWaalsContact O-CB 3.29Å; G24-M28 WeakPolarHBondContact O-CB 3.44Å; G24-M28 WeakPolarHBondContact O-CG 3.49Å; G24-M28 PolarHBondContact O-N 3.17Å
25	F	97.8	Very high	95.3	Very high	54 Å²	54	26 Å²	26	24%	0.237	13%	0.127	C	C	.	.	H	α-helix	trans	-63.4	-57.2	173.4	-175.9	-91	0	0	0	110.6	C21 L22 F23 S27 M28 F29 I147 V150 A151	C21-F25 WeakPolarHBondContact O-CB 3.37Å; C21-F25 PolarHBondContact O-N 3.08Å; L22-F25 PolarHBondContact O-N 3.19Å; F23-F25 VanDerWaalsContact C-N 3.32Å; F23-F25 PolarHBondContact O-N 3.49Å; F25-S27 VanDerWaalsContact C-N 3.33Å; F25-S27 PolarHBondContact O-N 3.22Å; F25-M28 PolarHBondContact O-N 2.9Å; F25-F29 HydrophobicContact CE1-CB 4.5Å; F25-F29 HydrophobicContact CE1-CD2 4.07Å; F25-F29 HydrophobicContact CE1-CG 4.5Å; F25-F29 AromaticContact CZ-CD2 3.88Å; F25-F29 HydrophobicContact CZ-CD2 3.88Å; F25-F29 HydrophobicContact CZ-CE2 4.39Å; F25-F29 VanDerWaalsContact O-CB 3.3Å; F25-F29 WeakPolarHBondContact O-CB 3.45Å; F25-F29 PolarHBondContact O-N 3.37Å; F25-I147 HydrophobicContact CB-CD1 4.42Å; F25-I147 HydrophobicContact CB-CG1 3.83Å; F25-I147 HydrophobicContact CD2-CD1 3.74Å; F25-I147 HydrophobicContact CD2-CG1 3.95Å; F25-I147 HydrophobicContact CG-CD1 4.49Å; F25-I147 HydrophobicContact CG-CG1 4.37Å; F25-V150 HydrophobicContact CE2-CG1 4.5Å; F25-A151 HydrophobicContact CB-CB 4.43Å; F25-A151 HydrophobicContact CD2-CB 3.61Å; F25-A151 HydrophobicContact CE2-CB 3.96Å; F25-A151 HydrophobicContact CG-CB 4.04Å; F25-A151 VanDerWaalsContact O-CB 3.25Å; F25-A151 WeakPolarHBondContact O-CB 3.29Å
26	F	97.8	Very high	95.5	Very high	55 Å²	55	21.2 Å²	21.2	24%	0.241	11%	0.109	C	C	.	.	H	α-helix	trans	-70.8	-29	-175.4	-74.7	-67.9	0	0	0	113.2	L22 F23 C180 V183 A184 F187	L22-F26 HydrophobicContact CD2-CE2 4.44Å; L22-F26 WeakPolarHBondContact O-CD2 3.48Å; L22-F26 PolarHBondContact O-N 3.03Å; F23-F26 PolarHBondContact O-N 3.43Å; F26-C180 CarbonylContact O-C 3.46Å; F26-C180 WeakPolarHBondContact O-CB 3.41Å; F26-V183 HydrophobicContact CB-CB 4.45Å; F26-V183 HydrophobicContact CB-CG1 4.35Å; F26-V183 HydrophobicContact CD1-CB 4.08Å; F26-V183 HydrophobicContact CD1-CG1 3.81Å; F26-V183 HydrophobicContact CD2-CG1 3.61Å; F26-V183 HydrophobicContact CE1-CB 4.5Å; F26-V183 HydrophobicContact CE1-CG1 3.95Å; F26-V183 HydrophobicContact CE2-CG1 3.77Å; F26-V183 HydrophobicContact CG-CB 4.11Å; F26-V183 HydrophobicContact CG-CG1 3.66Å; F26-V183 HydrophobicContact CZ-CG1 3.93Å; F26-A184 HydrophobicContact CB-CB 3.88Å; F26-F187 AromaticContact CD2-CD2 3.87Å; F26-F187 HydrophobicContact CD2-CD2 3.87Å; F26-F187 AromaticContact CD2-CE2 3.65Å; F26-F187 HydrophobicContact CD2-CE2 3.65Å; F26-F187 HydrophobicContact CE2-CD2 4.28Å; F26-F187 AromaticContact CE2-CE2 3.58Å; F26-F187 HydrophobicContact CE2-CE2 3.58Å; F26-F187 HydrophobicContact CE2-CZ 4.42Å
27	S	95.6	Very high	95.8	Very high	7 Å²	7	21.1 Å²	21.1	5%	0.049	11%	0.108	C	C	.	.	H	α-helix	trans	-72.4	-29.9	175.7	71.8	0	0	0	0	111.9	F23 G24 F25 R30	F23-S27 VanDerWaalsContact O-CB 3.23Å; F23-S27 WeakPolarHBondContact O-CB 3.44Å; F23-S27 PolarHBondContact O-N 3.36Å; F23-S27 PolarHBondContact O-OG 2.72Å; F23-S27 VanDerWaalsContact O-OG 3.1Å; G24-S27 WeakPolarHBondContact CA-OG 3.3Å; G24-S27 PolarHBondContact O-OG 2.93Å; F25-S27 VanDerWaalsContact C-N 3.33Å; F25-S27 PolarHBondContact O-N 3.22Å; S27-R30 PolarHBondContact O-NE 3.28Å; S27-R30 PolarHBondContact O-NH2 3.5Å
28	M	95.1	Very high	95.9	Very high	27 Å²	27	20.8 Å²	20.8	13%	0.133	11%	0.106	C	C	.	.	H	α-helix	trans	-100.6	-12.5	-178.3	-66.3	-62.1	-70.9	0	0	114.5	G24 F25 R30 T148 A151 Y152	G24-M28 VanDerWaalsContact O-CB 3.29Å; G24-M28 WeakPolarHBondContact O-CB 3.44Å; G24-M28 WeakPolarHBondContact O-CG 3.49Å; G24-M28 PolarHBondContact O-N 3.17Å; F25-M28 PolarHBondContact O-N 2.9Å; M28-R30 PolarHBondContact O-N 2.89Å; M28-T148 HydrophobicContact CG-CG2 3.75Å; M28-A151 HydrophobicContact CB-CB 4.08Å; M28-Y152 HydrophobicContact CE-CD2 4.44Å
29	F	96.9	Very high	96	Very high	28 Å²	28	17.5 Å²	17.5	12%	0.123	9%	0.086	C	C	.	.			trans	-72.1	89.4	172.4	-166.5	-82.6	0	0	0	109.9	F25 P31 A151 A154 L158 C180	F25-F29 HydrophobicContact CE1-CB 4.5Å; F25-F29 HydrophobicContact CE1-CD2 4.07Å; F25-F29 HydrophobicContact CE1-CG 4.5Å; F25-F29 AromaticContact CZ-CD2 3.88Å; F25-F29 HydrophobicContact CZ-CD2 3.88Å; F25-F29 HydrophobicContact CZ-CE2 4.39Å; F25-F29 VanDerWaalsContact O-CB 3.3Å; F25-F29 WeakPolarHBondContact O-CB 3.45Å; F25-F29 PolarHBondContact O-N 3.37Å; F29-P31 HydrophobicContact CE1-CG 4.37Å; F29-A151 HydrophobicContact CB-CB 4.28Å; F29-A151 WeakPolarHBondContact CD2-O 3.12Å; F29-A154 HydrophobicContact CD2-CB 4.2Å; F29-A154 HydrophobicContact CE2-CB 3.72Å; F29-L158 HydrophobicContact CE1-CD2 3.77Å; F29-L158 HydrophobicContact CZ-CB 4.29Å; F29-L158 HydrophobicContact CZ-CD2 3.6Å; F29-C180 VanDerWaalsContact CD1-SG 3.56Å
30	R	94.6	Very high	96	Very high	15 Å²	15	16.6 Å²	16.6	6%	0.057	8%	0.081	C	C	.	.			trans	-127.8	78.2	-170.7	-62.9	169.6	-172.3	171.3	7	111.2	S27 M28 S32 E33 F91	S27-R30 PolarHBondContact O-NE 3.28Å; S27-R30 PolarHBondContact O-NH2 3.5Å; M28-R30 PolarHBondContact O-N 2.89Å; R30-S32 PolarHBondContact O-N 2.76Å; R30-E33 HydrophobicContact CB-CB 4.32Å; R30-E33 WeakPolarHBondContact O-CB 3.39Å; R30-E33 PolarHBondContact O-N 3.4Å; R30-F91 HydrophobicContact CG-CZ 4.05Å
31	P	95.8	Very high	96	Very high	0 Å²	0	17.3 Å²	17.3	0%	0	9%	0.086	C	C	.	.	T	Hydrogen-bonded Turn	trans	-59.7	-27.5	179.6	21.9	-33.3	0	0	0	114	F29 E33 G155 A159 L173 I176 S177	F29-P31 HydrophobicContact CE1-CG 4.37Å; P31-E33 VanDerWaalsContact C-N 3.26Å; P31-E33 PolarHBondContact O-N 3.19Å; P31-G155 WeakPolarHBondContact CA-O 3.25Å; P31-G155 WeakPolarHBondContact CB-O 3.35Å; P31-A159 HydrophobicContact CB-CB 3.68Å; P31-A159 WeakPolarHBondContact O-CB 3.4Å; P31-L173 HydrophobicContact CB-CD2 4.45Å; P31-I176 HydrophobicContact CG-CB 4.04Å; P31-I176 HydrophobicContact CG-CG2 3.66Å; P31-S177 VanDerWaalsContact CD-OG 3.25Å; P31-S177 WeakPolarHBondContact CD-OG 3.23Å
32	S	95.8	Very high	95.8	Very high	0 Å²	0	18.1 Å²	18.1	0%	0	9%	0.088	C	C	.	.	T	Hydrogen-bonded Turn	trans	-63.9	-25.5	176.9	50.3	0	0	0	0	114.8	R30 A34 F35 L36 Y95 S177	R30-S32 PolarHBondContact O-N 2.76Å; S32-A34 VanDerWaalsContact C-N 3.33Å; S32-A34 PolarHBondContact O-N 2.99Å; S32-F35 CarbonylContact O-C 3.5Å; S32-F35 PolarHBondContact O-N 3.36Å; S32-L36 PolarHBondContact O-N 3.45Å; S32-Y95 WeakPolarHBondContact OG-CE1 3.45Å; S32-Y95 PolarHBondContact OG-OH 2.78Å; S32-S177 WeakPolarHBondContact CB-OG 3.21Å; S32-S177 PolarHBondContact N-OG 2.85Å; S32-S177 WeakPolarHBondContact OG-CB 3.35Å; S32-S177 PolarHBondContact OG-OG 3.41Å
33	E	93.1	Very high	95.5	Very high	36 Å²	36	20.1 Å²	20.1	17%	0.168	11%	0.105	C	C	.	.	G	3₁₀ helix	trans	-58.9	-42.3	-165.2	-165	72	-176.1	0	0	112.8	R30 P31 F35 Y95 Y152 Q294	R30-E33 HydrophobicContact CB-CB 4.32Å; R30-E33 WeakPolarHBondContact O-CB 3.39Å; R30-E33 PolarHBondContact O-N 3.4Å; P31-E33 VanDerWaalsContact C-N 3.26Å; P31-E33 PolarHBondContact O-N 3.19Å; E33-F35 PolarHBondContact O-N 3.04Å; E33-Y95 PolarHBondContact OE2-OH 3.22Å; E33-Y152 HydrophobicContact CB-CE2 4.45Å; E33-Y152 HydrophobicContact CG-CE2 4.17Å; E33-Q294 PolarHBondContact O-NE2 2.87Å
34	A	95	Very high	95.2	Very high	3 Å²	3	23 Å²	23	3%	0.025	13%	0.125	C	C	.	.	G	3₁₀ helix	trans	-72.6	-6.9	-179.1	0	0	0	0	0	114	S32 Q294 N310 E314	S32-A34 VanDerWaalsContact C-N 3.33Å; S32-A34 PolarHBondContact O-N 2.99Å; A34-Q294 PolarHBondContact O-OE1 3.32Å; A34-N310 HydrophobicContact CB-CB 4.17Å; A34-N310 WeakPolarHBondContact O-CB 3.32Å; A34-N310 PolarHBondContact O-ND2 3.18Å; A34-N310 VanDerWaalsContact O-ND2 3.13Å; A34-E314 HydrophobicContact CB-CB 4.35Å
35	F	96.2	Very high	95	Very high	0 Å²	0	23.4 Å²	23.4	0%	0	13%	0.127	C	C	.	.	G	3₁₀ helix	trans	-126.5	19.6	-174.1	-62.9	-83.3	0	0	0	112.3	S32 E33 P38 F39 A159 V163 Y170 L173 I308 N310	S32-F35 CarbonylContact O-C 3.5Å; S32-F35 PolarHBondContact O-N 3.36Å; E33-F35 PolarHBondContact O-N 3.04Å; F35-P38 HydrophobicContact CD1-CG 4.33Å; F35-F39 VanDerWaalsContact O-CB 3.25Å; F35-F39 WeakPolarHBondContact O-CB 3.41Å; F35-F39 PolarHBondContact O-N 3.14Å; F35-A159 HydrophobicContact CD2-CB 4.02Å; F35-A159 HydrophobicContact CE2-CB 3.65Å; F35-V163 HydrophobicContact CD1-CG2 4.32Å; F35-V163 HydrophobicContact CD2-CG2 4.44Å; F35-V163 HydrophobicContact CE1-CB 4.31Å; F35-V163 HydrophobicContact CE1-CG1 4.06Å; F35-V163 HydrophobicContact CE1-CG2 3.97Å; F35-V163 HydrophobicContact CE2-CG2 4.1Å; F35-V163 HydrophobicContact CZ-CB 4.14Å; F35-V163 HydrophobicContact CZ-CG1 4.33Å; F35-V163 HydrophobicContact CZ-CG2 3.85Å; F35-Y170 HydrophobicContact CB-CD1 3.98Å; F35-Y170 HydrophobicContact CB-CE1 4.37Å; F35-Y170 AromaticContact CD1-CD1 3.96Å; F35-Y170 HydrophobicContact CD1-CD1 3.96Å; F35-Y170 AromaticContact CD1-CE1 3.52Å; F35-Y170 HydrophobicContact CD1-CE1 3.52Å; F35-Y170 HydrophobicContact CE1-CE1 4.11Å; F35-Y170 HydrophobicContact CG-CD1 4.14Å; F35-Y170 HydrophobicContact CG-CE1 4.17Å; F35-L173 HydrophobicContact CB-CD1 4.04Å; F35-L173 HydrophobicContact CD2-CD1 3.6Å; F35-L173 HydrophobicContact CE2-CD1 4.29Å; F35-L173 HydrophobicContact CG-CD1 3.92Å; F35-I308 HydrophobicContact CD1-CD1 3.77Å; F35-I308 HydrophobicContact CE1-CD1 3.68Å; F35-I308 HydrophobicContact CE1-CG1 4.14Å; F35-N310 HydrophobicContact CE1-CB 4.36Å
36	L	96.4	Very high	94.7	Very high	24 Å²	24	27.5 Å²	27.5	13%	0.126	15%	0.151	C	C	.	.	H	α-helix	trans	-59.3	-52	178	177.2	61.8	0	0	0	111.9	S32 F39 L40 L98 F174	S32-L36 PolarHBondContact O-N 3.45Å; L36-F39 WeakPolarHBondContact O-CB 3.42Å; L36-F39 PolarHBondContact O-N 2.82Å; L36-L40 HydrophobicContact CD1-CD1 4.08Å; L36-L40 HydrophobicContact CD1-CG 4.22Å; L36-L40 HydrophobicContact CG-CD1 4.26Å; L36-L40 WeakPolarHBondContact O-CG 3.39Å; L36-L40 PolarHBondContact O-N 3.35Å; L36-L98 HydrophobicContact CD1-CD1 4.05Å; L36-L98 HydrophobicContact CD1-CD2 4.06Å; L36-F174 HydrophobicContact CD1-CE1 4.07Å; L36-F174 HydrophobicContact CD1-CZ 3.85Å
37	I	96.6	Very high	94.6	Very high	5 Å²	5	25.8 Å²	25.8	3%	0.026	15%	0.145	C	C	.	.	H	α-helix	trans	-69.1	-44.5	-178.8	-56.9	-56.3	0	0	0	112.1	F39 L40 S41 L57 Q294 V295 E298	I37-F39 VanDerWaalsContact C-N 3.25Å; I37-F39 PolarHBondContact O-N 2.71Å; I37-L40 PolarHBondContact O-N 3.08Å; I37-S41 VanDerWaalsContact O-CB 3.3Å; I37-S41 WeakPolarHBondContact O-CB 3.16Å; I37-S41 PolarHBondContact O-N 3.14Å; I37-S41 PolarHBondContact O-OG 3.15Å; I37-L57 HydrophobicContact CD1-CD1 4.09Å; I37-L57 HydrophobicContact CD1-CD2 4.37Å; I37-Q294 HydrophobicContact CB-CB 3.85Å; I37-Q294 HydrophobicContact CG1-CB 3.42Å; I37-Q294 VanDerWaalsContact CG1-CB 3.42Å; I37-V295 HydrophobicContact CD1-CG2 3.82Å; I37-V295 HydrophobicContact CG1-CG2 3.92Å; I37-V295 HydrophobicContact CG2-CG2 4.34Å; I37-E298 HydrophobicContact CG2-CB 3.91Å; I37-E298 HydrophobicContact CG2-CG 4.2Å
38	P	95.6	Very high	94.5	Very high	0 Å²	0	28.9 Å²	28.9	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-52.1	-42.6	170.5	-31.4	35.8	0	0	0	113.5	F35 S41 E42 Y170 I308	F35-P38 HydrophobicContact CD1-CG 4.33Å; P38-S41 PolarHBondContact O-N 2.75Å; P38-E42 PolarHBondContact O-N 3.5Å; P38-Y170 HydrophobicContact CB-CD2 4.13Å; P38-Y170 HydrophobicContact CB-CE1 4.32Å; P38-Y170 HydrophobicContact CB-CE2 3.7Å; P38-I308 HydrophobicContact CB-CD1 4.06Å; P38-I308 HydrophobicContact CG-CD1 3.65Å
39	F	96	Very high	94.4	Very high	5 Å²	5	30.2 Å²	30.2	2%	0.022	18%	0.175	C	C	.	.	H	α-helix	trans	-65	-45.3	176.8	171	-106.2	0	0	0	113	F35 L36 I37 S41 E42 L98 F174	F35-F39 VanDerWaalsContact O-CB 3.25Å; F35-F39 WeakPolarHBondContact O-CB 3.41Å; F35-F39 PolarHBondContact O-N 3.14Å; L36-F39 WeakPolarHBondContact O-CB 3.42Å; L36-F39 PolarHBondContact O-N 2.82Å; I37-F39 VanDerWaalsContact C-N 3.25Å; I37-F39 PolarHBondContact O-N 2.71Å; F39-S41 PolarHBondContact O-N 2.66Å; F39-E42 WeakPolarHBondContact O-CB 3.29Å; F39-E42 PolarHBondContact O-N 3.45Å; F39-L98 HydrophobicContact CE1-CB 4.33Å; F39-L98 VanDerWaalsContact CE1-O 3.26Å; F39-L98 WeakPolarHBondContact CE1-O 3.39Å; F39-L98 WeakPolarHBondContact CZ-O 3.28Å; F39-F174 HydrophobicContact CB-CD2 4.4Å; F39-F174 HydrophobicContact CB-CE2 3.47Å; F39-F174 VanDerWaalsContact CB-CE2 3.47Å; F39-F174 HydrophobicContact CB-CZ 3.97Å; F39-F174 HydrophobicContact CD1-CD2 4.13Å; F39-F174 HydrophobicContact CD1-CE1 4.16Å; F39-F174 AromaticContact CD1-CE2 3.51Å; F39-F174 HydrophobicContact CD1-CE2 3.51Å; F39-F174 AromaticContact CD1-CZ 3.51Å; F39-F174 HydrophobicContact CD1-CZ 3.51Å; F39-F174 HydrophobicContact CD2-CD2 4.07Å; F39-F174 AromaticContact CD2-CE2 3.93Å; F39-F174 HydrophobicContact CD2-CE2 3.93Å; F39-F174 HydrophobicContact CE1-CD2 4.42Å; F39-F174 HydrophobicContact CE1-CE1 4.41Å; F39-F174 HydrophobicContact CE1-CE2 4.2Å; F39-F174 HydrophobicContact CE1-CZ 4.16Å; F39-F174 HydrophobicContact CE2-CD2 4.37Å; F39-F174 AromaticContact CG-CD2 3.93Å; F39-F174 HydrophobicContact CG-CD2 3.93Å; F39-F174 AromaticContact CG-CE2 3.34Å; F39-F174 HydrophobicContact CG-CE2 3.34Å; F39-F174 AromaticContact CG-CZ 3.83Å; F39-F174 HydrophobicContact CG-CZ 3.83Å
40	L	96.3	Very high	94.2	Very high	1 Å²	1	32 Å²	32	1%	0.005	19%	0.19	C	C	.	.	H	α-helix	trans	-68.5	-22.4	176.7	-66.6	-179.2	0	0	0	113	L36 I37 E42 K45 L47 M52 L98 M107	L36-L40 HydrophobicContact CD1-CD1 4.08Å; L36-L40 HydrophobicContact CD1-CG 4.22Å; L36-L40 HydrophobicContact CG-CD1 4.26Å; L36-L40 WeakPolarHBondContact O-CG 3.39Å; L36-L40 PolarHBondContact O-N 3.35Å; I37-L40 PolarHBondContact O-N 3.08Å; L40-E42 VanDerWaalsContact C-N 3.34Å; L40-K45 WeakPolarHBondContact O-CB 3.45Å; L40-L47 HydrophobicContact CB-CD1 4.3Å; L40-L47 HydrophobicContact CD2-CD1 4.19Å; L40-M52 HydrophobicContact CB-CG 4.45Å; L40-M52 HydrophobicContact CB-SD 3.46Å; L40-M52 WeakPolarHBondContact CB-SD 3.33Å; L40-L98 HydrophobicContact CD2-CD2 4.18Å; L40-M107 HydrophobicContact CD2-CG 4.35Å; L40-M107 HydrophobicContact CD2-SD 3.46Å; L40-M107 WeakPolarHBondContact CD2-SD 3.32Å
41	S	94.2	Very high	94.3	Very high	18 Å²	18	33.9 Å²	33.9	13%	0.126	20%	0.199	C	C	.	.	T	Hydrogen-bonded Turn	trans	-86.5	-2.9	176.4	-52.2	0	0	0	0	113	I37 P38 F39 M52 Q304	I37-S41 VanDerWaalsContact O-CB 3.3Å; I37-S41 WeakPolarHBondContact O-CB 3.16Å; I37-S41 PolarHBondContact O-N 3.14Å; I37-S41 PolarHBondContact O-OG 3.15Å; P38-S41 PolarHBondContact O-N 2.75Å; F39-S41 PolarHBondContact O-N 2.66Å; S41-M52 WeakPolarHBondContact OG-CE 3.25Å; S41-Q304 PolarHBondContact O-NE2 2.82Å
42	E	93	Very high	94.3	Very high	40 Å²	40	34.3 Å²	34.3	19%	0.187	20%	0.201	C	C	.	.	S	Bend	trans	-62.5	144.9	174.1	-76	-174.1	176.5	0	0	110.6	P38 F39 L40 S44 K45 Y170	P38-E42 PolarHBondContact O-N 3.5Å; F39-E42 WeakPolarHBondContact O-CB 3.29Å; F39-E42 PolarHBondContact O-N 3.45Å; L40-E42 VanDerWaalsContact C-N 3.34Å; E42-S44 PolarHBondContact O-N 3.29Å; E42-S44 PolarHBondContact OE2-OG 3.33Å; E42-K45 PolarHBondContact O-N 3.47Å; E42-Y170 HydrophobicContact CG-CD2 4.08Å; E42-Y170 WeakPolarHBondContact OE1-CD2 3.31Å
43	P	90.1	Very high	94.4	Very high	102 Å²	102	34.4 Å²	34.4	66%	0.662	20%	0.202	S	C	*	.	T	Hydrogen-bonded Turn	trans	-56	-24.1	175.7	-25.5	35	0	0	0	113.6	K45 N46	P43-K45 VanDerWaalsContact C-N 3.26Å; P43-K45 PolarHBondContact O-N 2.83Å; P43-N46 PolarHBondContact O-N 3.48Å
44	S	90.4	Very high	94.5	Very high	64 Å²	64	33 Å²	33	45%	0.448	20%	0.195	S	C	.	.	T	Hydrogen-bonded Turn	trans	-65.4	-24.4	177.6	68.9	0	0	0	0	113.9	E42 Q102	E42-S44 PolarHBondContact O-N 3.29Å; E42-S44 PolarHBondContact OE2-OG 3.33Å; S44-Q102 PolarHBondContact O-NE2 3.47Å; S44-Q102 PolarHBondContact O-OE1 2.99Å
45	K	92.9	Very high	94.6	Very high	7 Å²	7	35.1 Å²	35.1	3%	0.03	21%	0.205	C	C	.	.	T	Hydrogen-bonded Turn	trans	-94.8	-24.8	179	-67.9	-71.9	165	-174.9	0	112.9	L40 E42 P43 L47 L98 L99 G101	L40-K45 WeakPolarHBondContact O-CB 3.45Å; E42-K45 PolarHBondContact O-N 3.47Å; P43-K45 VanDerWaalsContact C-N 3.26Å; P43-K45 PolarHBondContact O-N 2.83Å; K45-L47 VanDerWaalsContact C-N 3.3Å; K45-L47 HydrophobicContact CB-CD1 4.19Å; K45-L47 HydrophobicContact CB-CG 4.3Å; K45-L47 PolarHBondContact O-N 2.77Å; K45-L98 WeakPolarHBondContact CE-O 3.4Å; K45-L98 PolarHBondContact NZ-O 3.12Å; K45-L99 PolarHBondContact NZ-O 2.93Å; K45-G101 PolarHBondContact NZ-O 3.17Å
46	N	91.4	Very high	94.7	Very high	140 Å²	140	35.1 Å²	35.1	75%	0.749	21%	0.205	S	C	*	.			trans	51.3	45.6	177.8	-167.9	48.2	0	0	0	113.1	P43	P43-N46 PolarHBondContact O-N 3.48Å
47	L	94.9	Very high	94.8	Very high	20 Å²	20	34.2 Å²	34.2	11%	0.105	20%	0.2	C	C	.	.			trans	-107.7	138	177.3	-62.8	168.3	0	0	0	110.1	L40 K45 M52 I56 V104 M107	L40-L47 HydrophobicContact CB-CD1 4.3Å; L40-L47 HydrophobicContact CD2-CD1 4.19Å; K45-L47 VanDerWaalsContact C-N 3.3Å; K45-L47 HydrophobicContact CB-CD1 4.19Å; K45-L47 HydrophobicContact CB-CG 4.3Å; K45-L47 PolarHBondContact O-N 2.77Å; L47-M52 HydrophobicContact CB-CG 4Å; L47-M52 HydrophobicContact CB-SD 4.37Å; L47-M52 HydrophobicContact CD1-CG 4.34Å; L47-I56 HydrophobicContact CD1-CD1 4Å; L47-I56 HydrophobicContact CD2-CD1 4.06Å; L47-V104 HydrophobicContact CD2-CG2 4.09Å; L47-M107 HydrophobicContact CD1-CG 3.78Å
48	T	94	Very high	94.9	Very high	72 Å²	72	34 Å²	34	44%	0.442	20%	0.199	S	C	.	.			trans	-85.2	156.4	174.2	67.9	0	0	0	0	111.2	E51 M52	T48-E51 WeakPolarHBondContact CB-OE2 3.38Å; T48-E51 WeakPolarHBondContact CG2-OE2 3.48Å; T48-E51 PolarHBondContact N-OE2 2.9Å; T48-E51 PolarHBondContact O-N 2.79Å; T48-E51 WeakPolarHBondContact OG1-CB 3.42Å; T48-E51 WeakPolarHBondContact OG1-CG 3.36Å; T48-E51 PolarHBondContact OG1-N 3.38Å; T48-E51 PolarHBondContact OG1-OE2 2.86Å; T48-M52 PolarHBondContact O-N 3.43Å
49	S	92.4	Very high	95	Very high	54 Å²	54	35.4 Å²	35.4	38%	0.378	21%	0.207	S	C	.	.	H	α-helix	trans	-57.6	-42.7	176.5	176.2	0	0	0	0	113.2	M52 T53	S49-M52 PolarHBondContact O-N 3.14Å; S49-T53 VanDerWaalsContact O-CB 3.28Å; S49-T53 WeakPolarHBondContact O-CB 3.43Å; S49-T53 PolarHBondContact O-N 3.38Å; S49-T53 PolarHBondContact O-OG1 3.49Å
50	P	94.5	Very high	95.1	Very high	66 Å²	66	36.3 Å²	36.3	43%	0.429	21%	0.211	S	C	.	.	H	α-helix	trans	-62.5	-40.4	173.7	-24.8	36	0	0	0	113.9	T53 N54	P50-T53 PolarHBondContact O-N 3.15Å; P50-N54 VanDerWaalsContact O-CB 3.31Å; P50-N54 WeakPolarHBondContact O-CB 3.17Å; P50-N54 PolarHBondContact O-N 3.42Å; P50-N54 PolarHBondContact O-OD1 3.15Å
51	E	96.1	Very high	95.2	Very high	55 Å²	55	36.3 Å²	36.3	26%	0.257	21%	0.211	S	C	.	.	I	π-helix	trans	-62	-46.6	176.7	-74.4	164.4	147.9	0	0	111	T48 T53 E55 I56 V104	T48-E51 WeakPolarHBondContact CB-OE2 3.38Å; T48-E51 WeakPolarHBondContact CG2-OE2 3.48Å; T48-E51 PolarHBondContact N-OE2 2.9Å; T48-E51 PolarHBondContact O-N 2.79Å; T48-E51 WeakPolarHBondContact OG1-CB 3.42Å; T48-E51 WeakPolarHBondContact OG1-CG 3.36Å; T48-E51 PolarHBondContact OG1-N 3.38Å; T48-E51 PolarHBondContact OG1-OE2 2.86Å; E51-T53 PolarHBondContact O-N 2.86Å; E51-E55 WeakPolarHBondContact O-CA 3.35Å; E51-E55 VanDerWaalsContact O-CB 3.31Å; E51-E55 WeakPolarHBondContact O-CB 3.3Å; E51-E55 PolarHBondContact O-N 3.4Å; E51-E55 VanDerWaalsContact O-N 3.1Å; E51-I56 PolarHBondContact O-N 2.89Å; E51-V104 HydrophobicContact CB-CG2 4.01Å; E51-V104 HydrophobicContact CG-CG2 3.98Å
52	M	95.5	Very high	95.4	Very high	8 Å²	8	38.5 Å²	38.5	4%	0.039	22%	0.217	C	C	.	.	I	π-helix	trans	-60.1	-47.6	175.7	-71	-174.8	-75	0	0	111.8	L40 S41 L47 T48 S49 I56 L57	L40-M52 HydrophobicContact CB-CG 4.45Å; L40-M52 HydrophobicContact CB-SD 3.46Å; L40-M52 WeakPolarHBondContact CB-SD 3.33Å; S41-M52 WeakPolarHBondContact OG-CE 3.25Å; L47-M52 HydrophobicContact CB-CG 4Å; L47-M52 HydrophobicContact CB-SD 4.37Å; L47-M52 HydrophobicContact CD1-CG 4.34Å; T48-M52 PolarHBondContact O-N 3.43Å; S49-M52 PolarHBondContact O-N 3.14Å; M52-I56 HydrophobicContact CG-CD1 4.31Å; M52-L57 WeakPolarHBondContact O-CB 3.18Å; M52-L57 VanDerWaalsContact O-CG 3.27Å; M52-L57 WeakPolarHBondContact O-CG 3.32Å; M52-L57 PolarHBondContact O-N 3.22Å
53	T	96.9	Very high	95.6	Very high	2 Å²	2	36.9 Å²	36.9	1%	0.012	21%	0.21	C	C	.	.	I	π-helix	trans	-74.6	-46.4	-172	-51.5	0	0	0	0	112.9	S49 P50 E51 P58 Y292 V295 V420	S49-T53 VanDerWaalsContact O-CB 3.28Å; S49-T53 WeakPolarHBondContact O-CB 3.43Å; S49-T53 PolarHBondContact O-N 3.38Å; S49-T53 PolarHBondContact O-OG1 3.49Å; P50-T53 PolarHBondContact O-N 3.15Å; E51-T53 PolarHBondContact O-N 2.86Å; T53-P58 WeakPolarHBondContact O-CD 3.14Å; T53-Y292 HydrophobicContact CG2-CD1 4.21Å; T53-Y292 HydrophobicContact CG2-CE1 4.39Å; T53-V295 HydrophobicContact CG2-CG1 4.4Å; T53-V295 WeakPolarHBondContact OG1-CG1 3.36Å; T53-V420 HydrophobicContact CG2-CG1 4.42Å; T53-V420 WeakPolarHBondContact O-CG1 3.37Å
54	N	97.1	Very high	96	Very high	6 Å²	6	33.5 Å²	33.5	3%	0.032	18%	0.184	C	C	.	.	I	π-helix	trans	-105.9	-13.3	-165.6	-53.7	102	0	0	0	113.2	P50 V420 Q422 Q426 L427	P50-N54 VanDerWaalsContact O-CB 3.31Å; P50-N54 WeakPolarHBondContact O-CB 3.17Å; P50-N54 PolarHBondContact O-N 3.42Å; P50-N54 PolarHBondContact O-OD1 3.15Å; N54-V420 WeakPolarHBondContact CB-O 3.37Å; N54-V420 PolarHBondContact ND2-O 2.91Å; N54-Q422 PolarHBondContact O-N 2.89Å; N54-Q426 HydrophobicContact CB-CG 3.85Å; N54-L427 PolarHBondContact ND2-O 2.67Å
55	E	97.1	Very high	96.3	Very high	49 Å²	49	32.1 Å²	32.1	23%	0.229	17%	0.171	C	C	.	.	I	π-helix	trans	-119.1	-38.8	-179.3	-55.3	-174.8	-134.5	0	0	113.8	E51 V104 Q108 Q422	E51-E55 WeakPolarHBondContact O-CA 3.35Å; E51-E55 VanDerWaalsContact O-CB 3.31Å; E51-E55 WeakPolarHBondContact O-CB 3.3Å; E51-E55 PolarHBondContact O-N 3.4Å; E51-E55 VanDerWaalsContact O-N 3.1Å; E55-V104 HydrophobicContact CB-CG1 4.08Å; E55-Q108 PolarHBondContact O-NE2 3.25Å; E55-Q422 HydrophobicContact CG-CG 4.45Å
56	I	97.8	Very high	96.6	Very high	0 Å²	0	35 Å²	35	0%	0	20%	0.196	C	C	.	.	I	π-helix	trans	-88.3	-64.8	-174.9	-64.3	167.8	0	0	0	111.3	L47 E51 M52 P58 V59 V104 M107 Q108 E111	L47-I56 HydrophobicContact CD1-CD1 4Å; L47-I56 HydrophobicContact CD2-CD1 4.06Å; E51-I56 PolarHBondContact O-N 2.89Å; M52-I56 HydrophobicContact CG-CD1 4.31Å; I56-P58 VanDerWaalsContact C-N 3.35Å; I56-V59 WeakPolarHBondContact O-CB 3.22Å; I56-V59 PolarHBondContact O-N 3.13Å; I56-V104 HydrophobicContact CD1-CG1 4.49Å; I56-V104 HydrophobicContact CD1-CG2 4.49Å; I56-V104 HydrophobicContact CG1-CG1 3.95Å; I56-M107 HydrophobicContact CD1-CB 3.63Å; I56-M107 HydrophobicContact CD1-CG 4.09Å; I56-M107 HydrophobicContact CG1-CB 3.97Å; I56-M107 HydrophobicContact CG2-CB 3.77Å; I56-Q108 HydrophobicContact CG1-CG 4.28Å; I56-E111 HydrophobicContact CG2-CG 3.58Å
57	L	97.6	Very high	96.8	Very high	4 Å²	4	29.2 Å²	29.2	2%	0.021	17%	0.166	C	C	.	.	T	Hydrogen-bonded Turn	trans	-59	-29.7	-174.4	-68.7	174.4	0	0	0	115.7	I37 M52 V59 W60 N291 Y292 V295	I37-L57 HydrophobicContact CD1-CD1 4.09Å; I37-L57 HydrophobicContact CD1-CD2 4.37Å; M52-L57 WeakPolarHBondContact O-CB 3.18Å; M52-L57 VanDerWaalsContact O-CG 3.27Å; M52-L57 WeakPolarHBondContact O-CG 3.32Å; M52-L57 PolarHBondContact O-N 3.22Å; L57-V59 PolarHBondContact O-N 2.85Å; L57-W60 PolarHBondContact O-N 3.47Å; L57-N291 PolarHBondContact O-ND2 2.68Å; L57-Y292 HydrophobicContact CB-CD1 4.46Å; L57-Y292 HydrophobicContact CB-CE1 3.72Å; L57-Y292 HydrophobicContact CD1-CD1 3.83Å; L57-Y292 HydrophobicContact CD1-CE1 3.91Å; L57-V295 HydrophobicContact CD1-CG2 3.52Å
58	P	98.3	Very high	96.8	Very high	1 Å²	1	28.9 Å²	28.9	1%	0.006	16%	0.164	C	C	.	.	H	α-helix	trans	-58.8	-29.8	173.1	-31.6	40.8	0	0	0	113.9	T53 I56 W60 T61 Y62 T416 V420	T53-P58 WeakPolarHBondContact O-CD 3.14Å; I56-P58 VanDerWaalsContact C-N 3.35Å; P58-W60 VanDerWaalsContact C-N 3.28Å; P58-W60 PolarHBondContact O-N 3.09Å; P58-T61 WeakPolarHBondContact O-CB 3.49Å; P58-T61 PolarHBondContact O-N 3.15Å; P58-Y62 HydrophobicContact CB-CD2 4.42Å; P58-Y62 HydrophobicContact CB-CE2 3.78Å; P58-Y62 VanDerWaalsContact O-CD2 3.25Å; P58-Y62 WeakPolarHBondContact O-CD2 3.47Å; P58-Y62 PolarHBondContact O-N 3.35Å; P58-Y62 VanDerWaalsContact O-N 3.13Å; P58-T416 HydrophobicContact CB-CG2 3.6Å; P58-T416 HydrophobicContact CG-CG2 4.14Å; P58-V420 HydrophobicContact CG-CG1 3.96Å
59	V	98.3	Very high	96.7	Very high	29 Å²	29	28.1 Å²	28.1	18%	0.176	16%	0.161	C	C	.	.	H	α-helix	trans	-62.7	-35.1	-177.7	179.1	0	0	0	0	111.8	I56 L57 T61 Y62 S63 Q108 E111 F112	I56-V59 WeakPolarHBondContact O-CB 3.22Å; I56-V59 PolarHBondContact O-N 3.13Å; L57-V59 PolarHBondContact O-N 2.85Å; V59-T61 VanDerWaalsContact C-N 3.34Å; V59-T61 PolarHBondContact O-N 3.13Å; V59-Y62 PolarHBondContact O-N 3.24Å; V59-S63 VanDerWaalsContact O-CB 3.26Å; V59-S63 WeakPolarHBondContact O-CB 3.48Å; V59-S63 PolarHBondContact O-N 3.17Å; V59-S63 PolarHBondContact O-OG 3.49Å; V59-Q108 WeakPolarHBondContact CG1-O 3.38Å; V59-Q108 HydrophobicContact CG2-CB 4.04Å; V59-Q108 HydrophobicContact CG2-CG 3.8Å; V59-E111 HydrophobicContact CB-CB 4.08Å; V59-E111 HydrophobicContact CG1-CB 4.35Å; V59-F112 HydrophobicContact CG1-CB 3.98Å
60	W	98.2	Very high	96.7	Very high	24 Å²	24	28.7 Å²	28.7	9%	0.091	16%	0.163	C	C	.	.	H	α-helix	trans	-59.1	-45.5	172.8	168.1	76.1	0	0	0	111.7	L57 P58 Y62 S63 Y64 E111 F114 S118 N287 N291	L57-W60 PolarHBondContact O-N 3.47Å; P58-W60 VanDerWaalsContact C-N 3.28Å; P58-W60 PolarHBondContact O-N 3.09Å; W60-Y62 PolarHBondContact O-N 2.93Å; W60-S63 WeakPolarHBondContact CA-OG 3.46Å; W60-S63 PolarHBondContact O-N 2.89Å; W60-S63 PolarHBondContact O-OG 3.1Å; W60-S63 VanDerWaalsContact O-OG 3.08Å; W60-Y64 HydrophobicContact CH2-CD1 4.49Å; W60-Y64 AromaticContact CZ2-CD1 3.85Å; W60-Y64 HydrophobicContact CZ2-CD1 3.85Å; W60-Y64 HydrophobicContact CZ2-CE1 4.3Å; W60-Y64 WeakPolarHBondContact O-CB 3.44Å; W60-Y64 PolarHBondContact O-N 3.26Å; W60-E111 HydrophobicContact CB-CB 4.31Å; W60-E111 WeakPolarHBondContact CB-OE2 3.36Å; W60-F114 AromaticContact CD1-CD1 3.51Å; W60-F114 HydrophobicContact CG-CD1 4.36Å; W60-F114 AromaticContact NE1-CD1 3.76Å; W60-S118 PolarHBondContact NE1-OG 3.01Å; W60-N287 HydrophobicContact CH2-CB 4.36Å; W60-N291 HydrophobicContact CE3-CB 4.19Å; W60-N291 VanDerWaalsContact CE3-OD1 3.3Å; W60-N291 HydrophobicContact CZ3-CB 3.87Å
61	T	98	Very high	96.6	Very high	2 Å²	2	26 Å²	26	1%	0.012	15%	0.146	C	C	.	.	H	α-helix	trans	-61.2	-46.5	179.2	-63.1	0	0	0	0	111	P58 V59 L65 Q412 T416	P58-T61 WeakPolarHBondContact O-CB 3.49Å; P58-T61 PolarHBondContact O-N 3.15Å; V59-T61 VanDerWaalsContact C-N 3.34Å; V59-T61 PolarHBondContact O-N 3.13Å; T61-L65 PolarHBondContact O-N 3.29Å; T61-Q412 HydrophobicContact CG2-CB 4.49Å; T61-Q412 HydrophobicContact CG2-CG 3.79Å; T61-Q412 PolarHBondContact OG1-NE2 3.29Å; T61-T416 PolarHBondContact OG1-OG1 3.25Å
62	Y	98.3	Very high	96.2	Very high	64 Å²	64	28.7 Å²	28.7	25%	0.251	16%	0.157	S	C	.	.	H	α-helix	trans	-67.1	-46.4	-178.8	-57.9	-40.1	0	0	0	112.6	P58 V59 W60 Y64 L65 A66 T413 T416 M417 D421	P58-Y62 HydrophobicContact CB-CD2 4.42Å; P58-Y62 HydrophobicContact CB-CE2 3.78Å; P58-Y62 VanDerWaalsContact O-CD2 3.25Å; P58-Y62 WeakPolarHBondContact O-CD2 3.47Å; P58-Y62 PolarHBondContact O-N 3.35Å; P58-Y62 VanDerWaalsContact O-N 3.13Å; V59-Y62 PolarHBondContact O-N 3.24Å; W60-Y62 PolarHBondContact O-N 2.93Å; Y62-Y64 VanDerWaalsContact C-N 3.34Å; Y62-L65 PolarHBondContact O-N 3.29Å; Y62-A66 VanDerWaalsContact O-CB 3.3Å; Y62-A66 WeakPolarHBondContact O-CB 3.49Å; Y62-A66 PolarHBondContact O-N 3.15Å; Y62-T413 HydrophobicContact CD1-CG2 3.71Å; Y62-T413 HydrophobicContact CE1-CG2 3.9Å; Y62-T416 HydrophobicContact CE1-CG2 4.15Å; Y62-M417 HydrophobicContact CE1-CB 4.48Å; Y62-M417 WeakPolarHBondContact OH-CA 3.34Å; Y62-D421 VanDerWaalsContact CE2-OD2 3.24Å; Y62-D421 WeakPolarHBondContact CE2-OD2 3.25Å; Y62-D421 WeakPolarHBondContact OH-CB 3.36Å; Y62-D421 PolarHBondContact OH-OD2 3.38Å
63	S	98.3	Very high	95.8	Very high	5 Å²	5	32.3 Å²	32.3	4%	0.035	18%	0.179	C	C	.	.	H	α-helix	trans	-65.7	-37.9	179.5	57.2	0	0	0	0	111.5	V59 W60 A66 T67 F112 G115	V59-S63 VanDerWaalsContact O-CB 3.26Å; V59-S63 WeakPolarHBondContact O-CB 3.48Å; V59-S63 PolarHBondContact O-N 3.17Å; V59-S63 PolarHBondContact O-OG 3.49Å; W60-S63 WeakPolarHBondContact CA-OG 3.46Å; W60-S63 PolarHBondContact O-N 2.89Å; W60-S63 PolarHBondContact O-OG 3.1Å; W60-S63 VanDerWaalsContact O-OG 3.08Å; S63-A66 PolarHBondContact O-N 3.06Å; S63-T67 VanDerWaalsContact O-CB 3.26Å; S63-T67 WeakPolarHBondContact O-CB 3.29Å; S63-T67 WeakPolarHBondContact O-CG2 3.47Å; S63-T67 PolarHBondContact O-N 3.42Å; S63-T67 PolarHBondContact O-OG1 3.24Å; S63-F112 PolarHBondContact OG-O 3.34Å; S63-G115 WeakPolarHBondContact OG-CA 3.43Å
64	Y	98	Very high	95.4	Very high	32 Å²	32	35.6 Å²	35.6	13%	0.125	20%	0.196	C	C	.	.	H	α-helix	trans	-61.6	-50.5	175.3	-172.3	-171.7	0	0	0	111.3	W60 Y62 A66 T67 L68 A119 L409	W60-Y64 HydrophobicContact CH2-CD1 4.49Å; W60-Y64 AromaticContact CZ2-CD1 3.85Å; W60-Y64 HydrophobicContact CZ2-CD1 3.85Å; W60-Y64 HydrophobicContact CZ2-CE1 4.3Å; W60-Y64 WeakPolarHBondContact O-CB 3.44Å; W60-Y64 PolarHBondContact O-N 3.26Å; Y62-Y64 VanDerWaalsContact C-N 3.34Å; Y64-A66 PolarHBondContact O-N 3.43Å; Y64-T67 PolarHBondContact O-N 3.47Å; Y64-T67 PolarHBondContact O-OG1 3.18Å; Y64-L68 HydrophobicContact CD2-CB 4.43Å; Y64-L68 HydrophobicContact CE2-CB 4.45Å; Y64-L68 HydrophobicContact CE2-CD1 4.38Å; Y64-L68 VanDerWaalsContact O-CB 3.28Å; Y64-L68 WeakPolarHBondContact O-CB 3.46Å; Y64-L68 PolarHBondContact O-N 3.36Å; Y64-A119 HydrophobicContact CD2-CB 4.09Å; Y64-A119 HydrophobicContact CE2-CB 4.25Å; Y64-L409 HydrophobicContact CD1-CD1 4.1Å; Y64-L409 HydrophobicContact CD1-CD2 3.68Å; Y64-L409 HydrophobicContact CD2-CD1 3.78Å; Y64-L409 HydrophobicContact CE1-CD1 4.11Å; Y64-L409 HydrophobicContact CE1-CD2 3.64Å; Y64-L409 HydrophobicContact CE2-CD1 3.75Å; Y64-L409 HydrophobicContact CG-CD1 3.94Å; Y64-L409 HydrophobicContact CG-CD2 4.29Å
65	L	97.8	Very high	94.9	Very high	34 Å²	34	35.7 Å²	35.7	18%	0.178	20%	0.197	C	C	.	.	H	α-helix	trans	-59.4	-45.8	176.1	176.1	64.3	0	0	0	112	T61 Y62 T67 P69 F406 L409 V410 T413	T61-L65 PolarHBondContact O-N 3.29Å; Y62-L65 PolarHBondContact O-N 3.29Å; L65-T67 PolarHBondContact O-N 3.12Å; L65-P69 WeakPolarHBondContact O-CD 3.23Å; L65-F406 HydrophobicContact CD1-CD2 4.06Å; L65-F406 HydrophobicContact CD1-CE2 3.73Å; L65-F406 HydrophobicContact CD1-CZ 4.44Å; L65-L409 HydrophobicContact CB-CB 4.31Å; L65-L409 HydrophobicContact CD1-CB 3.77Å; L65-V410 HydrophobicContact CD1-CG2 3.8Å; L65-V410 HydrophobicContact CD2-CG2 4.31Å; L65-T413 HydrophobicContact CD2-CG2 3.85Å; L65-T413 WeakPolarHBondContact CD2-OG1 3.37Å
66	A	97.7	Very high	94.1	Very high	67 Å²	67	33.8 Å²	33.8	55%	0.554	19%	0.188	S	C	*	.	H	α-helix	trans	-67.7	-34.5	-175.8	0	0	0	0	0	113	Y62 S63 Y64 P70	Y62-A66 VanDerWaalsContact O-CB 3.3Å; Y62-A66 WeakPolarHBondContact O-CB 3.49Å; Y62-A66 PolarHBondContact O-N 3.15Å; S63-A66 PolarHBondContact O-N 3.06Å; Y64-A66 PolarHBondContact O-N 3.43Å; A66-P70 VanDerWaalsContact O-CD 3.28Å; A66-P70 WeakPolarHBondContact O-CD 3.35Å
67	T	96.7	Very high	93.2	Very high	20 Å²	20	41.4 Å²	41.4	12%	0.123	22%	0.218	C	C	.	.	H	α-helix	trans	-90.7	-21.8	-175.4	60.2	0	0	0	0	113	S63 Y64 L65 P70 V71 V116 A119	S63-T67 VanDerWaalsContact O-CB 3.26Å; S63-T67 WeakPolarHBondContact O-CB 3.29Å; S63-T67 WeakPolarHBondContact O-CG2 3.47Å; S63-T67 PolarHBondContact O-N 3.42Å; S63-T67 PolarHBondContact O-OG1 3.24Å; Y64-T67 PolarHBondContact O-N 3.47Å; Y64-T67 PolarHBondContact O-OG1 3.18Å; L65-T67 PolarHBondContact O-N 3.12Å; T67-P70 WeakPolarHBondContact O-CD 3.4Å; T67-V71 VanDerWaalsContact O-CB 3.28Å; T67-V71 WeakPolarHBondContact O-CB 3.43Å; T67-V71 WeakPolarHBondContact O-CG2 3.49Å; T67-V71 PolarHBondContact O-N 3.02Å; T67-V116 HydrophobicContact CG2-CG2 3.87Å; T67-A119 WeakPolarHBondContact OG1-CB 3.48Å
68	L	94.8	Very high	92.6	Very high	12 Å²	12	44.3 Å²	44.3	6%	0.063	23%	0.233	C	C	.	.	H	α-helix	trans	-56.4	-53.5	-179.7	174.8	69.8	0	0	0	113.2	Y64 V71 F72 A119 I122 T405 L409	Y64-L68 HydrophobicContact CD2-CB 4.43Å; Y64-L68 HydrophobicContact CE2-CB 4.45Å; Y64-L68 HydrophobicContact CE2-CD1 4.38Å; Y64-L68 VanDerWaalsContact O-CB 3.28Å; Y64-L68 WeakPolarHBondContact O-CB 3.46Å; Y64-L68 PolarHBondContact O-N 3.36Å; L68-V71 PolarHBondContact O-N 3.2Å; L68-F72 WeakPolarHBondContact O-CB 3.4Å; L68-F72 PolarHBondContact O-N 3.23Å; L68-A119 HydrophobicContact CB-CB 4.45Å; L68-I122 HydrophobicContact CD1-CD1 3.22Å; L68-T405 HydrophobicContact CD2-CG2 4.24Å; L68-L409 HydrophobicContact CB-CD1 4.2Å; L68-L409 HydrophobicContact CD2-CD1 3.47Å; L68-L409 VanDerWaalsContact CD2-CD1 3.47Å; L68-L409 HydrophobicContact CD2-CG 4.49Å; L68-L409 HydrophobicContact CG-CD1 4.39Å
69	P	91.9	Very high	91.9	Very high	56 Å²	56	48.6 Å²	48.6	36%	0.364	25%	0.249	S	C	.	.	H	α-helix	trans	-63.1	-46.2	-178.9	-16.9	27.9	0	0	0	113.7	L65 V71 F72 V73 F406	L65-P69 WeakPolarHBondContact O-CD 3.23Å; P69-V71 PolarHBondContact O-N 3.32Å; P69-F72 PolarHBondContact O-N 3.41Å; P69-V73 WeakPolarHBondContact O-CG2 3.49Å; P69-V73 PolarHBondContact O-N 2.99Å; P69-V73 VanDerWaalsContact O-N 3.12Å; P69-F406 HydrophobicContact CG-CD2 4.26Å; P69-F406 HydrophobicContact CG-CE2 3.91Å
70	P	92.6	Very high	91.4	Very high	67 Å²	67	47.4 Å²	47.4	44%	0.435	24%	0.242	S	C	.	.	H	α-helix	trans	-57.6	-45.2	173.2	-26.3	34.4	0	0	0	113	A66 T67 F72 V73 L74	A66-P70 VanDerWaalsContact O-CD 3.28Å; A66-P70 WeakPolarHBondContact O-CD 3.35Å; T67-P70 WeakPolarHBondContact O-CD 3.4Å; P70-F72 VanDerWaalsContact C-N 3.32Å; P70-F72 PolarHBondContact O-N 3.29Å; P70-V73 PolarHBondContact O-N 3.17Å; P70-L74 WeakPolarHBondContact O-CB 2.87Å; P70-L74 VanDerWaalsContact O-CG 3.23Å; P70-L74 WeakPolarHBondContact O-CG 3.45Å; P70-L74 PolarHBondContact O-N 3.31Å
71	V	92.6	Very high	91.1	Very high	9 Å²	9	47.9 Å²	47.9	6%	0.055	24%	0.244	C	C	.	.	H	α-helix	trans	-63.6	-39.5	179.1	168.4	0	0	0	0	111.1	T67 L68 P69 V73 L74 T75 V83 A119 T120	T67-V71 VanDerWaalsContact O-CB 3.28Å; T67-V71 WeakPolarHBondContact O-CB 3.43Å; T67-V71 WeakPolarHBondContact O-CG2 3.49Å; T67-V71 PolarHBondContact O-N 3.02Å; L68-V71 PolarHBondContact O-N 3.2Å; P69-V71 PolarHBondContact O-N 3.32Å; V71-V73 PolarHBondContact O-N 3.4Å; V71-L74 PolarHBondContact O-N 3.45Å; V71-T75 VanDerWaalsContact O-CB 3.29Å; V71-T75 WeakPolarHBondContact O-CB 3.33Å; V71-T75 PolarHBondContact O-N 2.91Å; V71-T75 PolarHBondContact O-OG1 3.1Å; V71-V83 HydrophobicContact CG1-CG1 3.96Å; V71-A119 HydrophobicContact CB-CB 4.16Å; V71-A119 HydrophobicContact CG1-CB 4.34Å; V71-A119 WeakPolarHBondContact CG1-O 3.48Å; V71-A119 HydrophobicContact CG2-CB 4.01Å; V71-T120 HydrophobicContact CG1-CG2 3.84Å; V71-T120 HydrophobicContact CG2-CG2 3.92Å
72	F	86.8	Confident	90.8	Very high	112 Å²	112	50.1 Å²	50.1	49%	0.491	26%	0.259	S	S	.	.	H	α-helix	trans	-59.2	-48.1	175.9	-178.4	-97.3	0	0	0	111.8	L68 P69 P70 T75 F199	L68-F72 WeakPolarHBondContact O-CB 3.4Å; L68-F72 PolarHBondContact O-N 3.23Å; P69-F72 PolarHBondContact O-N 3.41Å; P70-F72 VanDerWaalsContact C-N 3.32Å; P70-F72 PolarHBondContact O-N 3.29Å; F72-T75 PolarHBondContact O-N 3.18Å; F72-F199 HydrophobicContact CZ-CE2 4.44Å
73	V	87	Confident	90.6	Very high	84 Å²	84	47.2 Å²	47.2	51%	0.509	25%	0.248	S	C	.	.	H	α-helix	trans	-63.8	-45.7	177.1	176	0	0	0	0	111.3	P69 P70 V71 T75 Y77	P69-V73 WeakPolarHBondContact O-CG2 3.49Å; P69-V73 PolarHBondContact O-N 2.99Å; P69-V73 VanDerWaalsContact O-N 3.12Å; P70-V73 PolarHBondContact O-N 3.17Å; V71-V73 PolarHBondContact O-N 3.4Å; V73-T75 VanDerWaalsContact C-N 3.27Å; V73-T75 PolarHBondContact O-N 3.29Å; V73-Y77 WeakPolarHBondContact O-CB 3.33Å; V73-Y77 PolarHBondContact O-N 3.16Å; V73-Y77 VanDerWaalsContact O-N 3.15Å
74	L	88.1	Confident	90.4	Very high	70 Å²	70	47.1 Å²	47.1	37%	0.366	25%	0.247	S	C	.	.	H	α-helix	trans	-64	-31.7	179.2	-72.9	171.4	0	0	0	112.6	P70 V71 Y77 L78 V83	P70-L74 WeakPolarHBondContact O-CB 2.87Å; P70-L74 VanDerWaalsContact O-CG 3.23Å; P70-L74 WeakPolarHBondContact O-CG 3.45Å; P70-L74 PolarHBondContact O-N 3.31Å; V71-L74 PolarHBondContact O-N 3.45Å; L74-Y77 PolarHBondContact O-N 2.98Å; L74-L78 HydrophobicContact CB-CD1 4.36Å; L74-L78 HydrophobicContact CD2-CD1 4.16Å; L74-L78 HydrophobicContact CD2-CG 4.45Å; L74-L78 VanDerWaalsContact O-CB 3.23Å; L74-L78 WeakPolarHBondContact O-CB 3.4Å; L74-L78 WeakPolarHBondContact O-CG 3.48Å; L74-L78 PolarHBondContact O-N 3.38Å; L74-V83 HydrophobicContact CB-CG2 4.39Å
75	T	87.6	Confident	90.3	Very high	9 Å²	9	47.7 Å²	47.7	6%	0.055	25%	0.252	C	S	.	.	H	α-helix	trans	-62.7	-46.1	-178.4	-64.9	0	0	0	0	111.7	V71 F72 V73 R79 Y80 A123	V71-T75 VanDerWaalsContact O-CB 3.29Å; V71-T75 WeakPolarHBondContact O-CB 3.33Å; V71-T75 PolarHBondContact O-N 2.91Å; V71-T75 PolarHBondContact O-OG1 3.1Å; F72-T75 PolarHBondContact O-N 3.18Å; V73-T75 VanDerWaalsContact C-N 3.27Å; V73-T75 PolarHBondContact O-N 3.29Å; T75-R79 PolarHBondContact O-N 2.9Å; T75-Y80 HydrophobicContact CG2-CD1 3.25Å; T75-Y80 HydrophobicContact CG2-CE1 3.54Å; T75-Y80 HydrophobicContact CG2-CG 4.19Å; T75-Y80 PolarHBondContact O-N 3.38Å; T75-A123 HydrophobicContact CG2-CB 3.74Å
76	D	79.1	Confident	90.1	Very high	9 Å²	9	49.5 Å²	49.5	5%	0.048	26%	0.261	C	S	.	.	H	α-helix	trans	-74.3	-41.6	175.8	-158.8	59.2	0	0	0	111.5	L78 R79 Y80 S197 M198 F199 F200	D76-L78 PolarHBondContact O-N 2.92Å; D76-R79 PolarHBondContact O-N 2.65Å; D76-Y80 PolarHBondContact OD1-OH 2.83Å; D76-S197 WeakPolarHBondContact OD1-CB 3.42Å; D76-S197 WeakPolarHBondContact OD2-CB 3.38Å; D76-S197 PolarHBondContact OD2-OG 3.46Å; D76-M198 PolarHBondContact OD1-N 2.95Å; D76-F199 PolarHBondContact OD1-N 3.44Å; D76-F199 PolarHBondContact OD2-N 2.83Å; D76-F200 HydrophobicContact CB-CD2 4.17Å; D76-F200 HydrophobicContact CB-CE2 4.43Å; D76-F200 WeakPolarHBondContact OD2-CD2 3.4Å; D76-F200 PolarHBondContact OD2-N 2.84Å
77	Y	80.2	Confident	90.1	Very high	160 Å²	160	46.7 Å²	46.7	63%	0.627	24%	0.237	S	C	*	.	H	α-helix	trans	-62	-44.8	-178.3	-176.9	-102.6	0	0	0	112.8	V73 L74 R79	V73-Y77 WeakPolarHBondContact O-CB 3.33Å; V73-Y77 PolarHBondContact O-N 3.16Å; V73-Y77 VanDerWaalsContact O-N 3.15Å; L74-Y77 PolarHBondContact O-N 2.98Å; Y77-R79 VanDerWaalsContact C-N 3.33Å
78	L	84	Confident	90.1	Very high	64 Å²	64	46 Å²	46	34%	0.335	23%	0.232	S	C	.	.	T	Hydrogen-bonded Turn	trans	-89	3.6	-178.7	-60.3	179.7	0	0	0	113.6	L74 D76 Y80 P82 V83	L74-L78 HydrophobicContact CB-CD1 4.36Å; L74-L78 HydrophobicContact CD2-CD1 4.16Å; L74-L78 HydrophobicContact CD2-CG 4.45Å; L74-L78 VanDerWaalsContact O-CB 3.23Å; L74-L78 WeakPolarHBondContact O-CB 3.4Å; L74-L78 WeakPolarHBondContact O-CG 3.48Å; L74-L78 PolarHBondContact O-N 3.38Å; D76-L78 PolarHBondContact O-N 2.92Å; L78-Y80 PolarHBondContact O-N 2.95Å; L78-P82 HydrophobicContact CB-CB 4.12Å; L78-P82 HydrophobicContact CB-CG 4Å; L78-P82 HydrophobicContact CD1-CB 4.12Å; L78-P82 WeakPolarHBondContact O-CD 3.45Å; L78-P82 WeakPolarHBondContact O-CG 3.47Å; L78-V83 HydrophobicContact CD1-CG2 4.45Å
79	R	85	Confident	90.1	Very high	91 Å²	91	48.8 Å²	48.8	34%	0.343	25%	0.249	S	C	.	.	T	Hydrogen-bonded Turn	trans	55.7	50.2	-178.1	-50	-176.5	-174.2	-174.8	-2.2	112.7	T75 D76 Y77 K81 M193 P194	T75-R79 PolarHBondContact O-N 2.9Å; D76-R79 PolarHBondContact O-N 2.65Å; Y77-R79 VanDerWaalsContact C-N 3.33Å; R79-K81 PolarHBondContact O-N 3.17Å; R79-M193 HydrophobicContact CB-CE 4.25Å; R79-P194 VanDerWaalsContact CD-O 3.31Å; R79-P194 WeakPolarHBondContact CD-O 3.4Å; R79-P194 VanDerWaalsContact O-CD 3.3Å; R79-P194 WeakPolarHBondContact O-CD 3.25Å
80	Y	88	Confident	90.4	Very high	4 Å²	4	46.2 Å²	46.2	2%	0.016	23%	0.233	C	C	.	.	S	Bend	trans	66.5	-52.1	166.1	-47	-88.3	0	0	0	117	T75 D76 L78 V83 I84 A126 P194 M198	T75-Y80 HydrophobicContact CG2-CD1 3.25Å; T75-Y80 HydrophobicContact CG2-CE1 3.54Å; T75-Y80 HydrophobicContact CG2-CG 4.19Å; T75-Y80 PolarHBondContact O-N 3.38Å; D76-Y80 PolarHBondContact OD1-OH 2.83Å; L78-Y80 PolarHBondContact O-N 2.95Å; Y80-V83 WeakPolarHBondContact O-CA 3.48Å; Y80-V83 WeakPolarHBondContact O-CB 3.38Å; Y80-V83 PolarHBondContact O-N 2.97Å; Y80-I84 PolarHBondContact O-N 3.13Å; Y80-A126 HydrophobicContact CD1-CB 3.96Å; Y80-A126 HydrophobicContact CE1-CB 3.67Å; Y80-P194 HydrophobicContact CD2-CB 4.27Å; Y80-P194 HydrophobicContact CD2-CG 3.98Å; Y80-M198 HydrophobicContact CE1-CE 4.35Å; Y80-M198 WeakPolarHBondContact OH-CE 3.12Å; Y80-M198 WeakPolarHBondContact OH-CG 3.3Å
81	K	90.5	Very high	90.6	Very high	34 Å²	34	43.1 Å²	43.1	15%	0.148	21%	0.213	C	C	.	.	H	α-helix	trans	-56.9	-45.4	-172.7	-179.2	-176.7	-178.1	174	0	113.3	R79 V83 I84 M85 S188 L189 L191 M193	R79-K81 PolarHBondContact O-N 3.17Å; K81-V83 PolarHBondContact O-N 3.36Å; K81-I84 WeakPolarHBondContact O-CB 3.38Å; K81-I84 PolarHBondContact O-N 3.35Å; K81-M85 HydrophobicContact CD-CE 4.27Å; K81-M85 HydrophobicContact CG-CE 4.12Å; K81-M85 WeakPolarHBondContact O-CG 3.4Å; K81-M85 PolarHBondContact O-N 3.37Å; K81-S188 VanDerWaalsContact CE-O 3.3Å; K81-S188 WeakPolarHBondContact CE-O 3.21Å; K81-L189 PolarHBondContact NZ-O 2.89Å; K81-L191 HydrophobicContact CD-CB 4.49Å; K81-L191 VanDerWaalsContact CD-O 3.32Å; K81-L191 WeakPolarHBondContact CD-O 3.31Å; K81-L191 WeakPolarHBondContact CE-O 3.32Å; K81-L191 PolarHBondContact NZ-O 3.5Å; K81-M193 HydrophobicContact CB-SD 3.55Å; K81-M193 VanDerWaalsContact CB-SD 3.55Å; K81-M193 HydrophobicContact CD-CG 4.05Å; K81-M193 HydrophobicContact CD-SD 3.44Å; K81-M193 WeakPolarHBondContact CD-SD 3.18Å; K81-M193 HydrophobicContact CG-SD 4Å
82	P	92.7	Very high	90.8	Very high	50 Å²	50	43.8 Å²	43.8	33%	0.325	22%	0.219	S	C	.	.	H	α-helix	trans	-61.6	-32.2	175.9	-25.9	38.7	0	0	0	113.1	L78 M85 L86	L78-P82 HydrophobicContact CB-CB 4.12Å; L78-P82 HydrophobicContact CB-CG 4Å; L78-P82 HydrophobicContact CD1-CB 4.12Å; L78-P82 WeakPolarHBondContact O-CD 3.45Å; L78-P82 WeakPolarHBondContact O-CG 3.47Å; P82-M85 PolarHBondContact O-N 3.12Å; P82-L86 WeakPolarHBondContact O-CB 3.36Å; P82-L86 PolarHBondContact O-N 3.32Å
83	V	94.2	Very high	91.4	Very high	3 Å²	3	40.2 Å²	40.2	2%	0.018	21%	0.207	C	C	.	.	H	α-helix	trans	-73.2	-36.1	176.2	-176.6	0	0	0	0	111.4	V71 L74 L78 Y80 K81 M85 L86 H87 T120 A123	V71-V83 HydrophobicContact CG1-CG1 3.96Å; L74-V83 HydrophobicContact CB-CG2 4.39Å; L78-V83 HydrophobicContact CD1-CG2 4.45Å; Y80-V83 WeakPolarHBondContact O-CA 3.48Å; Y80-V83 WeakPolarHBondContact O-CB 3.38Å; Y80-V83 PolarHBondContact O-N 2.97Å; K81-V83 PolarHBondContact O-N 3.36Å; V83-M85 VanDerWaalsContact C-N 3.29Å; V83-M85 PolarHBondContact O-N 2.95Å; V83-L86 WeakPolarHBondContact O-CB 3.42Å; V83-L86 PolarHBondContact O-N 3.41Å; V83-H87 PolarHBondContact O-N 3.21Å; V83-T120 HydrophobicContact CG1-CG2 3.8Å; V83-A123 HydrophobicContact CB-CB 4Å; V83-A123 HydrophobicContact CG1-CB 3.65Å
84	I	94	Very high	91.9	Very high	2 Å²	2	36.3 Å²	36.3	1%	0.01	18%	0.183	C	C	.	.	H	α-helix	trans	-62.6	-37.5	171	-67.9	171.3	0	0	0	111.2	F23 Y80 K81 H87 V88 A123 Y127 L191	F23-I84 HydrophobicContact CD2-CG2 4.15Å; F23-I84 HydrophobicContact CE1-CG2 3.96Å; F23-I84 HydrophobicContact CE2-CG2 3.48Å; F23-I84 VanDerWaalsContact CE2-CG2 3.48Å; F23-I84 HydrophobicContact CZ-CG2 3.41Å; F23-I84 VanDerWaalsContact CZ-CG2 3.41Å; Y80-I84 PolarHBondContact O-N 3.13Å; K81-I84 WeakPolarHBondContact O-CB 3.38Å; K81-I84 PolarHBondContact O-N 3.35Å; I84-H87 WeakPolarHBondContact O-CB 3.42Å; I84-H87 PolarHBondContact O-N 3.47Å; I84-V88 PolarHBondContact O-N 3.34Å; I84-A123 HydrophobicContact CG1-CB 4.33Å; I84-Y127 HydrophobicContact CD1-CD2 3.6Å; I84-Y127 HydrophobicContact CD1-CE2 4.32Å; I84-Y127 HydrophobicContact CD1-CG 3.77Å; I84-L191 HydrophobicContact CD1-CD1 4.09Å; I84-L191 HydrophobicContact CG2-CD1 3.88Å
85	M	94.4	Very high	92.3	Very high	45 Å²	45	33.1 Å²	33.1	22%	0.222	17%	0.166	C	C	.	.	H	α-helix	trans	-68	-43.3	173.4	-69	177.4	169.2	0	0	111.6	K81 P82 V83 H87 V88 V89 S188 L189	K81-M85 HydrophobicContact CD-CE 4.27Å; K81-M85 HydrophobicContact CG-CE 4.12Å; K81-M85 WeakPolarHBondContact O-CG 3.4Å; K81-M85 PolarHBondContact O-N 3.37Å; P82-M85 PolarHBondContact O-N 3.12Å; V83-M85 VanDerWaalsContact C-N 3.29Å; V83-M85 PolarHBondContact O-N 2.95Å; M85-H87 VanDerWaalsContact C-N 3.25Å; M85-H87 PolarHBondContact O-N 3.34Å; M85-V88 PolarHBondContact O-N 3.48Å; M85-V89 WeakPolarHBondContact O-CG2 3.4Å; M85-V89 PolarHBondContact O-N 2.88Å; M85-S188 WeakPolarHBondContact CE-O 3.23Å; M85-L189 HydrophobicContact CE-CD2 3.8Å
86	L	95.5	Very high	92.8	Very high	72 Å²	72	36.5 Å²	36.5	38%	0.377	18%	0.184	S	C	.	.	H	α-helix	trans	-57	-40.1	174.4	177.6	63.2	0	0	0	111.6	P82 V83 V88 V89 A90 V116 T120	P82-L86 WeakPolarHBondContact O-CB 3.36Å; P82-L86 PolarHBondContact O-N 3.32Å; V83-L86 WeakPolarHBondContact O-CB 3.42Å; V83-L86 PolarHBondContact O-N 3.41Å; L86-V88 VanDerWaalsContact C-N 3.35Å; L86-V88 PolarHBondContact O-N 3.11Å; L86-V89 PolarHBondContact O-N 2.99Å; L86-A90 VanDerWaalsContact O-CB 3.26Å; L86-A90 WeakPolarHBondContact O-CB 3.37Å; L86-A90 PolarHBondContact O-N 3.4Å; L86-V116 HydrophobicContact CG-CG1 4.46Å; L86-T120 HydrophobicContact CD2-CG2 4Å; L86-T120 HydrophobicContact CG-CG2 4.18Å
87	H	96	Very high	93.7	Very high	8 Å²	8	39 Å²	39	4%	0.037	19%	0.194	C	C	.	.	H	α-helix	trans	-53.1	-51.6	175.4	179.1	88.5	0	0	0	111.6	V83 I84 M85 F91 V117 T120	V83-H87 PolarHBondContact O-N 3.21Å; I84-H87 WeakPolarHBondContact O-CB 3.42Å; I84-H87 PolarHBondContact O-N 3.47Å; M85-H87 VanDerWaalsContact C-N 3.25Å; M85-H87 PolarHBondContact O-N 3.34Å; H87-F91 WeakPolarHBondContact O-CB 3.36Å; H87-F91 PolarHBondContact O-N 3.33Å; H87-V117 VanDerWaalsContact CE1-CG1 3.5Å; H87-V117 WeakPolarHBondContact CE1-CG1 3.39Å; H87-V117 PolarHBondContact CE1-O 3.33Å; H87-V117 PolarHBondContact ND1-O 3.25Å; H87-T120 VanDerWaalsContact CA-OG1 3.29Å; H87-T120 WeakPolarHBondContact CA-OG1 3.22Å; H87-T120 VanDerWaalsContact CB-OG1 3.28Å; H87-T120 WeakPolarHBondContact CB-OG1 3.31Å; H87-T120 PolarHBondContact ND1-OG1 3.34Å
88	V	96.6	Very high	94.5	Very high	4 Å²	4	31.6 Å²	31.6	2%	0.024	17%	0.165	C	C	.	.	H	α-helix	trans	-71.5	-37.7	-177.1	-176.7	0	0	0	0	112.2	F23 I84 M85 L86 F91 A92 V181 A184 F185	F23-V88 HydrophobicContact CE2-CG2 3.4Å; F23-V88 HydrophobicContact CZ-CG2 3.79Å; I84-V88 PolarHBondContact O-N 3.34Å; M85-V88 PolarHBondContact O-N 3.48Å; L86-V88 VanDerWaalsContact C-N 3.35Å; L86-V88 PolarHBondContact O-N 3.11Å; V88-F91 WeakPolarHBondContact O-CB 3.36Å; V88-F91 PolarHBondContact O-N 3.38Å; V88-A92 WeakPolarHBondContact O-CB 3.41Å; V88-A92 PolarHBondContact O-N 2.82Å; V88-V181 HydrophobicContact CG1-CG1 3.62Å; V88-V181 VanDerWaalsContact CG1-O 3.22Å; V88-V181 WeakPolarHBondContact CG1-O 3.36Å; V88-A184 HydrophobicContact CG2-CB 4.45Å; V88-F185 HydrophobicContact CB-CB 4.48Å; V88-F185 HydrophobicContact CB-CD2 4.31Å; V88-F185 HydrophobicContact CG1-CB 3.57Å; V88-F185 HydrophobicContact CG1-CD2 4.12Å; V88-F185 HydrophobicContact CG1-CG 4.33Å
89	V	96.6	Very high	95.1	Very high	71 Å²	71	29.3 Å²	29.3	43%	0.43	15%	0.153	S	C	.	.	H	α-helix	trans	-63.3	-49.1	175.7	173	0	0	0	0	110.4	M85 L86 F91 A92 T93 F185	M85-V89 WeakPolarHBondContact O-CG2 3.4Å; M85-V89 PolarHBondContact O-N 2.88Å; L86-V89 PolarHBondContact O-N 2.99Å; V89-F91 VanDerWaalsContact C-N 3.26Å; V89-F91 PolarHBondContact O-N 2.88Å; V89-A92 PolarHBondContact O-N 2.9Å; V89-T93 WeakPolarHBondContact O-CB 3.31Å; V89-T93 PolarHBondContact O-N 3.44Å; V89-T93 PolarHBondContact O-OG1 3.37Å; V89-F185 HydrophobicContact CG2-CD2 4.48Å; V89-F185 HydrophobicContact CG2-CE2 4.07Å
90	A	97.9	Very high	95.6	Very high	2 Å²	2	31.2 Å²	31.2	2%	0.017	16%	0.164	C	C	.	.	H	α-helix	trans	-59	-40	176.4	0	0	0	0	0	111.5	L86 T93 S94 F113 V116 V117	L86-A90 VanDerWaalsContact O-CB 3.26Å; L86-A90 WeakPolarHBondContact O-CB 3.37Å; L86-A90 PolarHBondContact O-N 3.4Å; A90-T93 PolarHBondContact O-N 3.42Å; A90-S94 WeakPolarHBondContact O-CB 3.38Å; A90-S94 PolarHBondContact O-N 3.01Å; A90-F113 HydrophobicContact CB-CD1 4.23Å; A90-V116 HydrophobicContact CB-CB 4.08Å; A90-V116 HydrophobicContact CB-CG1 3.81Å; A90-V117 HydrophobicContact CB-CG2 3.99Å
91	F	96.9	Very high	95.9	Very high	2 Å²	2	31.1 Å²	31.1	1%	0.009	17%	0.165	C	C	.	.	H	α-helix	trans	-61.2	-52.5	175.9	-159	-69	0	0	0	112.1	R30 H87 V88 V89 T93 S94 Y95 F114 V117 V181	R30-F91 HydrophobicContact CG-CZ 4.05Å; H87-F91 WeakPolarHBondContact O-CB 3.36Å; H87-F91 PolarHBondContact O-N 3.33Å; V88-F91 WeakPolarHBondContact O-CB 3.36Å; V88-F91 PolarHBondContact O-N 3.38Å; V89-F91 VanDerWaalsContact C-N 3.26Å; V89-F91 PolarHBondContact O-N 2.88Å; F91-T93 VanDerWaalsContact C-N 3.29Å; F91-T93 PolarHBondContact O-N 2.94Å; F91-S94 WeakPolarHBondContact O-CB 3.26Å; F91-S94 PolarHBondContact O-N 3.22Å; F91-Y95 AromaticContact CD1-CD2 3.73Å; F91-Y95 HydrophobicContact CD1-CD2 3.73Å; F91-Y95 AromaticContact CD1-CE2 3.93Å; F91-Y95 HydrophobicContact CD1-CE2 3.93Å; F91-Y95 HydrophobicContact CD1-CG 4.19Å; F91-Y95 HydrophobicContact CE1-CD1 4.07Å; F91-Y95 AromaticContact CE1-CD2 3.31Å; F91-Y95 HydrophobicContact CE1-CD2 3.31Å; F91-Y95 AromaticContact CE1-CE1 3.85Å; F91-Y95 HydrophobicContact CE1-CE1 3.85Å; F91-Y95 AromaticContact CE1-CE2 3.08Å; F91-Y95 HydrophobicContact CE1-CE2 3.08Å; F91-Y95 AromaticContact CE1-CG 3.82Å; F91-Y95 HydrophobicContact CE1-CG 3.82Å; F91-Y95 AromaticContact CE1-CZ 3.37Å; F91-Y95 HydrophobicContact CE2-CE2 4.27Å; F91-Y95 AromaticContact CZ-CD2 3.97Å; F91-Y95 HydrophobicContact CZ-CD2 3.97Å; F91-Y95 HydrophobicContact CZ-CE1 4.37Å; F91-Y95 AromaticContact CZ-CE2 3.28Å; F91-Y95 HydrophobicContact CZ-CE2 3.28Å; F91-Y95 AromaticContact CZ-CZ 3.51Å; F91-Y95 PolarHBondContact O-N 3.3Å; F91-F114 HydrophobicContact CE2-CD2 4.47Å; F91-F114 AromaticContact CE2-CE2 3.92Å; F91-F114 HydrophobicContact CE2-CE2 3.92Å; F91-F114 HydrophobicContact CZ-CE2 4.4Å; F91-V117 VanDerWaalsContact CA-CG2 3.43Å; F91-V117 HydrophobicContact CB-CG2 3.69Å; F91-V117 HydrophobicContact CD2-CB 4.32Å; F91-V117 HydrophobicContact CD2-CG1 3.54Å; F91-V117 HydrophobicContact CD2-CG2 3.79Å; F91-V117 HydrophobicContact CE2-CG1 4.05Å; F91-V117 HydrophobicContact CG-CG2 4.14Å; F91-V117 VanDerWaalsContact N-CG2 3.32Å; F91-V181 HydrophobicContact CB-CG1 3.98Å; F91-V181 HydrophobicContact CD1-CB 4.13Å; F91-V181 HydrophobicContact CD1-CG1 3.8Å; F91-V181 HydrophobicContact CD1-CG2 3.29Å; F91-V181 HydrophobicContact CE1-CG2 3.44Å; F91-V181 VanDerWaalsContact CE1-CG2 3.44Å; F91-V181 HydrophobicContact CG-CG1 4.12Å; F91-V181 HydrophobicContact CG-CG2 3.98Å; F91-V181 HydrophobicContact CZ-CG2 4.3Å
92	A	97	Very high	96.1	Very high	24 Å²	24	34.4 Å²	34.4	20%	0.198	18%	0.181	C	C	.	.	H	α-helix	trans	-58.9	-43.5	178.6	0	0	0	0	0	110.9	V88 V89 Y95 L96 L178 V181	V88-A92 WeakPolarHBondContact O-CB 3.41Å; V88-A92 PolarHBondContact O-N 2.82Å; V89-A92 PolarHBondContact O-N 2.9Å; A92-Y95 PolarHBondContact O-N 2.89Å; A92-L96 VanDerWaalsContact O-CG 3.24Å; A92-L96 WeakPolarHBondContact O-CG 3.43Å; A92-L96 PolarHBondContact O-N 3.2Å; A92-L178 HydrophobicContact CB-CD1 4.02Å; A92-V181 HydrophobicContact CB-CG1 4.27Å
93	T	97.7	Very high	96.2	Very high	37 Å²	37	33.5 Å²	33.5	23%	0.227	18%	0.181	C	C	.	.	H	α-helix	trans	-60.1	-46.8	176.2	-58.6	0	0	0	0	112.2	V89 A90 F91 Y95 L96 F97 F113	V89-T93 WeakPolarHBondContact O-CB 3.31Å; V89-T93 PolarHBondContact O-N 3.44Å; V89-T93 PolarHBondContact O-OG1 3.37Å; A90-T93 PolarHBondContact O-N 3.42Å; F91-T93 VanDerWaalsContact C-N 3.29Å; F91-T93 PolarHBondContact O-N 2.94Å; T93-Y95 VanDerWaalsContact C-N 3.3Å; T93-Y95 PolarHBondContact O-N 3.36Å; T93-L96 PolarHBondContact O-N 3.16Å; T93-F97 HydrophobicContact CG2-CD2 3.87Å; T93-F97 HydrophobicContact CG2-CE2 3.58Å; T93-F97 WeakPolarHBondContact O-CD2 3.3Å; T93-F97 PolarHBondContact O-N 2.91Å; T93-F97 VanDerWaalsContact O-N 3.1Å; T93-F113 HydrophobicContact CG2-CD1 4.04Å; T93-F113 HydrophobicContact CG2-CD2 3.67Å; T93-F113 HydrophobicContact CG2-CE1 3.95Å; T93-F113 HydrophobicContact CG2-CE2 3.6Å; T93-F113 HydrophobicContact CG2-CG 3.91Å; T93-F113 HydrophobicContact CG2-CZ 3.74Å
94	S	97.9	Very high	96.3	Very high	1 Å²	1	34.7 Å²	34.7	1%	0.007	19%	0.188	C	C	.	.	H	α-helix	trans	-54.9	-47.7	175.5	179	0	0	0	0	111.2	A90 F91 L96 F97 L98 A110	A90-S94 WeakPolarHBondContact O-CB 3.38Å; A90-S94 PolarHBondContact O-N 3.01Å; F91-S94 WeakPolarHBondContact O-CB 3.26Å; F91-S94 PolarHBondContact O-N 3.22Å; S94-L96 PolarHBondContact O-N 3.43Å; S94-F97 PolarHBondContact O-N 2.92Å; S94-L98 WeakPolarHBondContact O-CG 3.27Å; S94-L98 PolarHBondContact O-N 3.12Å; S94-A110 WeakPolarHBondContact CB-O 3.34Å; S94-A110 PolarHBondContact OG-O 3.07Å
95	Y	96.9	Very high	96.5	Very high	3 Å²	3	41 Å²	41	1%	0.012	22%	0.219	C	C	.	.	H	α-helix	trans	-71	-32.3	-177.7	-88.4	-124.6	0	0	0	113.6	S32 E33 F91 A92 T93 F97 L98 L99 F174 S177	S32-Y95 WeakPolarHBondContact OG-CE1 3.45Å; S32-Y95 PolarHBondContact OG-OH 2.78Å; E33-Y95 PolarHBondContact OE2-OH 3.22Å; F91-Y95 AromaticContact CD1-CD2 3.73Å; F91-Y95 HydrophobicContact CD1-CD2 3.73Å; F91-Y95 AromaticContact CD1-CE2 3.93Å; F91-Y95 HydrophobicContact CD1-CE2 3.93Å; F91-Y95 HydrophobicContact CD1-CG 4.19Å; F91-Y95 HydrophobicContact CE1-CD1 4.07Å; F91-Y95 AromaticContact CE1-CD2 3.31Å; F91-Y95 HydrophobicContact CE1-CD2 3.31Å; F91-Y95 AromaticContact CE1-CE1 3.85Å; F91-Y95 HydrophobicContact CE1-CE1 3.85Å; F91-Y95 AromaticContact CE1-CE2 3.08Å; F91-Y95 HydrophobicContact CE1-CE2 3.08Å; F91-Y95 AromaticContact CE1-CG 3.82Å; F91-Y95 HydrophobicContact CE1-CG 3.82Å; F91-Y95 AromaticContact CE1-CZ 3.37Å; F91-Y95 HydrophobicContact CE2-CE2 4.27Å; F91-Y95 AromaticContact CZ-CD2 3.97Å; F91-Y95 HydrophobicContact CZ-CD2 3.97Å; F91-Y95 HydrophobicContact CZ-CE1 4.37Å; F91-Y95 AromaticContact CZ-CE2 3.28Å; F91-Y95 HydrophobicContact CZ-CE2 3.28Å; F91-Y95 AromaticContact CZ-CZ 3.51Å; F91-Y95 PolarHBondContact O-N 3.3Å; A92-Y95 PolarHBondContact O-N 2.89Å; T93-Y95 VanDerWaalsContact C-N 3.3Å; T93-Y95 PolarHBondContact O-N 3.36Å; Y95-F97 VanDerWaalsContact C-N 3.33Å; Y95-L98 HydrophobicContact CD2-CD1 4.11Å; Y95-L98 HydrophobicContact CE2-CD1 4.21Å; Y95-L98 PolarHBondContact O-N 3.23Å; Y95-L99 WeakPolarHBondContact O-CB 3.47Å; Y95-L99 WeakPolarHBondContact O-CG 3.39Å; Y95-L99 PolarHBondContact O-N 3.41Å; Y95-F174 AromaticContact CD1-CD1 3.87Å; Y95-F174 HydrophobicContact CD1-CD1 3.87Å; Y95-F174 AromaticContact CE1-CD1 3.75Å; Y95-F174 HydrophobicContact CE1-CD1 3.75Å; Y95-F174 HydrophobicContact CE1-CE1 4.27Å; Y95-S177 VanDerWaalsContact CE1-CB 3.45Å
96	L	97.6	Very high	96.6	Very high	81 Å²	81	41.3 Å²	41.3	42%	0.424	22%	0.221	S	C	.	.	H	α-helix	trans	-63.2	-41.8	171.4	-71	172	0	0	0	111	A92 T93 S94 F100 L178	A92-L96 VanDerWaalsContact O-CG 3.24Å; A92-L96 WeakPolarHBondContact O-CG 3.43Å; A92-L96 PolarHBondContact O-N 3.2Å; T93-L96 PolarHBondContact O-N 3.16Å; S94-L96 PolarHBondContact O-N 3.43Å; L96-F100 HydrophobicContact CD2-CD2 4.09Å; L96-F100 HydrophobicContact CD2-CE2 3.73Å; L96-F100 WeakPolarHBondContact O-CB 3.07Å; L96-F100 WeakPolarHBondContact O-CD2 3.38Å; L96-F100 PolarHBondContact O-N 2.64Å; L96-L178 HydrophobicContact CD2-CD2 3.99Å
97	F	97.7	Very high	96.7	Very high	60 Å²	60	37.9 Å²	37.9	26%	0.263	20%	0.203	S	C	.	.	H	α-helix	trans	-66.2	-40.1	172.8	-76.8	-65.5	0	0	0	112.3	T93 S94 Y95 G101 L106 M107 T109 A110 F113	T93-F97 HydrophobicContact CG2-CD2 3.87Å; T93-F97 HydrophobicContact CG2-CE2 3.58Å; T93-F97 WeakPolarHBondContact O-CD2 3.3Å; T93-F97 PolarHBondContact O-N 2.91Å; T93-F97 VanDerWaalsContact O-N 3.1Å; S94-F97 PolarHBondContact O-N 2.92Å; Y95-F97 VanDerWaalsContact C-N 3.33Å; F97-G101 WeakPolarHBondContact O-CA 3.34Å; F97-G101 PolarHBondContact O-N 3.46Å; F97-L106 HydrophobicContact CD1-CB 4.44Å; F97-L106 HydrophobicContact CD1-CD2 4.05Å; F97-L106 HydrophobicContact CE1-CD2 3.92Å; F97-M107 VanDerWaalsContact O-CE 3.3Å; F97-M107 WeakPolarHBondContact O-CE 3.19Å; F97-T109 HydrophobicContact CD1-CG2 4.49Å; F97-T109 HydrophobicContact CD2-CG2 3.92Å; F97-T109 HydrophobicContact CE1-CG2 4.2Å; F97-T109 HydrophobicContact CE2-CG2 3.59Å; F97-T109 HydrophobicContact CG-CG2 4.37Å; F97-T109 HydrophobicContact CZ-CG2 3.74Å; F97-A110 HydrophobicContact CB-CB 3.74Å; F97-F113 HydrophobicContact CD2-CD2 4.24Å; F97-F113 HydrophobicContact CD2-CE2 4.45Å; F97-F113 HydrophobicContact CE2-CD2 4.11Å; F97-F113 AromaticContact CE2-CE2 3.86Å; F97-F113 HydrophobicContact CE2-CE2 3.86Å
98	L	96.9	Very high	96.8	Very high	5 Å²	5	40.1 Å²	40.1	3%	0.026	21%	0.214	C	C	.	.	H	α-helix	trans	-62.4	-45.2	175.7	-70	170.7	0	0	0	111.7	L36 F39 L40 K45 S94 Y95 M107 A110 F174	L36-L98 HydrophobicContact CD1-CD1 4.05Å; L36-L98 HydrophobicContact CD1-CD2 4.06Å; F39-L98 HydrophobicContact CE1-CB 4.33Å; F39-L98 VanDerWaalsContact CE1-O 3.26Å; F39-L98 WeakPolarHBondContact CE1-O 3.39Å; F39-L98 WeakPolarHBondContact CZ-O 3.28Å; L40-L98 HydrophobicContact CD2-CD2 4.18Å; K45-L98 WeakPolarHBondContact CE-O 3.4Å; K45-L98 PolarHBondContact NZ-O 3.12Å; S94-L98 WeakPolarHBondContact O-CG 3.27Å; S94-L98 PolarHBondContact O-N 3.12Å; Y95-L98 HydrophobicContact CD2-CD1 4.11Å; Y95-L98 HydrophobicContact CE2-CD1 4.21Å; Y95-L98 PolarHBondContact O-N 3.23Å; L98-M107 HydrophobicContact CD2-SD 4.04Å; L98-A110 HydrophobicContact CD2-CB 3.79Å; L98-A110 HydrophobicContact CG-CB 3.78Å; L98-F174 HydrophobicContact CB-CD1 4.34Å; L98-F174 HydrophobicContact CB-CE1 4.24Å; L98-F174 HydrophobicContact CD1-CD1 4.4Å; L98-F174 HydrophobicContact CD1-CE1 3.83Å
99	L	96.7	Very high	96.9	Very high	16 Å²	16	42 Å²	42	8%	0.084	23%	0.225	C	C	.	.	H	α-helix	trans	-68.2	-55.2	-178.9	-79.2	165.3	0	0	0	111.9	K45 Y95 F174 Y175 L178	K45-L99 PolarHBondContact NZ-O 2.93Å; Y95-L99 WeakPolarHBondContact O-CB 3.47Å; Y95-L99 WeakPolarHBondContact O-CG 3.39Å; Y95-L99 PolarHBondContact O-N 3.41Å; L99-F174 HydrophobicContact CD1-CB 4.26Å; L99-F174 HydrophobicContact CD2-CB 3.49Å; L99-F174 VanDerWaalsContact CD2-CB 3.49Å; L99-F174 HydrophobicContact CD2-CG 4.37Å; L99-F174 HydrophobicContact CG-CB 3.88Å; L99-Y175 HydrophobicContact CD1-CD1 3.78Å; L99-Y175 HydrophobicContact CD1-CE1 3.75Å; L99-Y175 HydrophobicContact CD2-CD1 4.26Å; L99-Y175 HydrophobicContact CD2-CD2 4.38Å; L99-Y175 HydrophobicContact CD2-CE1 3.99Å; L99-Y175 HydrophobicContact CD2-CE2 4.11Å; L99-Y175 HydrophobicContact CD2-CG 4.44Å; L99-Y175 HydrophobicContact CG-CE1 4.41Å; L99-L178 HydrophobicContact CD1-CD2 4.01Å
100	F	96.3	Very high	97	Very high	131 Å²	131	38.6 Å²	38.6	58%	0.575	21%	0.205	S	C	*	.	H	α-helix	trans	-101.1	-16.4	-167.5	-56.4	-66.7	0	0	0	114.2	L96 Y175	L96-F100 HydrophobicContact CD2-CD2 4.09Å; L96-F100 HydrophobicContact CD2-CE2 3.73Å; L96-F100 WeakPolarHBondContact O-CB 3.07Å; L96-F100 WeakPolarHBondContact O-CD2 3.38Å; L96-F100 PolarHBondContact O-N 2.64Å; F100-Y175 HydrophobicContact CZ-CE1 4.08Å
101	G	94.4	Very high	97	Very high	3 Å²	3	38.8 Å²	38.8	3%	0.031	21%	0.205	C	C	.	.			trans	-73	151.4	177.4	0	0	0	0	0	112.7	K45 F97 M107	K45-G101 PolarHBondContact NZ-O 3.17Å; F97-G101 WeakPolarHBondContact O-CA 3.34Å; F97-G101 PolarHBondContact O-N 3.46Å; G101-M107 WeakPolarHBondContact O-CE 3.28Å
102	Q	94.2	Very high	97.1	Very high	102 Å²	102	42.9 Å²	42.9	48%	0.477	22%	0.223	S	C	.	.			trans	-134.8	140.9	177.6	-69.6	-67.7	-3.8	0	0	109.6	S44	S44-Q102 PolarHBondContact O-NE2 3.47Å; S44-Q102 PolarHBondContact O-OE1 2.99Å
103	G	94.9	Very high	97.2	Very high	32 Å²	32	44.4 Å²	44.4	33%	0.33	23%	0.225	S	C	.	.	S	Bend	trans	77.7	167.8	-179.6	0	0	0	0	0	115.2	M105 L106 M107	G103-M105 PolarHBondContact O-N 3.36Å; G103-L106 PolarHBondContact O-N 3.46Å; G103-M107 WeakPolarHBondContact O-CG 3.27Å; G103-M107 PolarHBondContact O-N 3.06Å
104	V	96.9	Very high	97.2	Very high	28 Å²	28	44 Å²	44	17%	0.17	22%	0.221	C	C	.	.	H	α-helix	trans	-57.3	-45.3	-170.5	177.1	0	0	0	0	112.9	L47 E51 E55 I56 L106 M107 Q108	L47-V104 HydrophobicContact CD2-CG2 4.09Å; E51-V104 HydrophobicContact CB-CG2 4.01Å; E51-V104 HydrophobicContact CG-CG2 3.98Å; E55-V104 HydrophobicContact CB-CG1 4.08Å; I56-V104 HydrophobicContact CD1-CG1 4.49Å; I56-V104 HydrophobicContact CD1-CG2 4.49Å; I56-V104 HydrophobicContact CG1-CG1 3.95Å; V104-L106 PolarHBondContact O-N 3.01Å; V104-M107 PolarHBondContact O-N 3.36Å; V104-Q108 HydrophobicContact CG1-CG 4.09Å; V104-Q108 WeakPolarHBondContact O-CB 3.21Å; V104-Q108 WeakPolarHBondContact O-CG 3.39Å; V104-Q108 PolarHBondContact O-N 2.84Å
105	M	97.2	Very high	97.2	Very high	134 Å²	134	44 Å²	44	66%	0.66	22%	0.22	S	C	*	.	H	α-helix	trans	-59.7	-42.8	-175.7	-174.9	-172.5	73.5	0	0	113.2	G103 T109	G103-M105 PolarHBondContact O-N 3.36Å; M105-T109 PolarHBondContact O-N 3.01Å; M105-T109 PolarHBondContact O-OG1 2.89Å
106	L	97.6	Very high	97.2	Very high	51 Å²	51	44.7 Å²	44.7	27%	0.267	23%	0.225	S	C	.	.	H	α-helix	trans	-74.4	-32.9	-179.7	-65.9	-177	0	0	0	111.6	F97 G103 V104 T109 A110	F97-L106 HydrophobicContact CD1-CB 4.44Å; F97-L106 HydrophobicContact CD1-CD2 4.05Å; F97-L106 HydrophobicContact CE1-CD2 3.92Å; G103-L106 PolarHBondContact O-N 3.46Å; V104-L106 PolarHBondContact O-N 3.01Å; L106-T109 WeakPolarHBondContact O-CB 3.12Å; L106-T109 PolarHBondContact O-N 3.39Å; L106-A110 PolarHBondContact O-N 3.15Å
107	M	97.8	Very high	97.2	Very high	1 Å²	1	40.9 Å²	40.9	1%	0.005	21%	0.205	C	C	.	.	H	α-helix	trans	-68.7	-41	172.7	-61.2	-56.9	113.3	0	0	112	L40 L47 I56 F97 L98 G101 G103 V104 T109 A110 E111	L40-M107 HydrophobicContact CD2-CG 4.35Å; L40-M107 HydrophobicContact CD2-SD 3.46Å; L40-M107 WeakPolarHBondContact CD2-SD 3.32Å; L47-M107 HydrophobicContact CD1-CG 3.78Å; I56-M107 HydrophobicContact CD1-CB 3.63Å; I56-M107 HydrophobicContact CD1-CG 4.09Å; I56-M107 HydrophobicContact CG1-CB 3.97Å; I56-M107 HydrophobicContact CG2-CB 3.77Å; F97-M107 VanDerWaalsContact O-CE 3.3Å; F97-M107 WeakPolarHBondContact O-CE 3.19Å; L98-M107 HydrophobicContact CD2-SD 4.04Å; G101-M107 WeakPolarHBondContact O-CE 3.28Å; G103-M107 WeakPolarHBondContact O-CG 3.27Å; G103-M107 PolarHBondContact O-N 3.06Å; V104-M107 PolarHBondContact O-N 3.36Å; M107-T109 PolarHBondContact O-N 3.42Å; M107-A110 WeakPolarHBondContact O-CA 3.43Å; M107-A110 WeakPolarHBondContact O-CB 3.28Å; M107-A110 PolarHBondContact O-N 3.46Å; M107-A110 VanDerWaalsContact O-N 3.07Å; M107-E111 WeakPolarHBondContact O-CG 3.49Å; M107-E111 PolarHBondContact O-N 3.24Å
108	Q	98.3	Very high	97.1	Very high	55 Å²	55	38.6 Å²	38.6	26%	0.257	20%	0.197	S	C	.	.	H	α-helix	trans	-58.5	-39.1	171.1	-74.9	177.8	-24.5	0	0	111.6	E55 I56 V59 V104 A110 E111 F112	E55-Q108 PolarHBondContact O-NE2 3.25Å; I56-Q108 HydrophobicContact CG1-CG 4.28Å; V59-Q108 WeakPolarHBondContact CG1-O 3.38Å; V59-Q108 HydrophobicContact CG2-CB 4.04Å; V59-Q108 HydrophobicContact CG2-CG 3.8Å; V104-Q108 HydrophobicContact CG1-CG 4.09Å; V104-Q108 WeakPolarHBondContact O-CB 3.21Å; V104-Q108 WeakPolarHBondContact O-CG 3.39Å; V104-Q108 PolarHBondContact O-N 2.84Å; Q108-A110 VanDerWaalsContact C-N 3.34Å; Q108-E111 PolarHBondContact O-N 2.88Å; Q108-F112 PolarHBondContact O-N 3.48Å
109	T	98.3	Very high	97.1	Very high	42 Å²	42	38.4 Å²	38.4	26%	0.258	20%	0.195	S	C	.	.	H	α-helix	trans	-64.5	-40.7	175	-54.8	0	0	0	0	110.9	F97 M105 L106 M107 F112 F113	F97-T109 HydrophobicContact CD1-CG2 4.49Å; F97-T109 HydrophobicContact CD2-CG2 3.92Å; F97-T109 HydrophobicContact CE1-CG2 4.2Å; F97-T109 HydrophobicContact CE2-CG2 3.59Å; F97-T109 HydrophobicContact CG-CG2 4.37Å; F97-T109 HydrophobicContact CZ-CG2 3.74Å; M105-T109 PolarHBondContact O-N 3.01Å; M105-T109 PolarHBondContact O-OG1 2.89Å; L106-T109 WeakPolarHBondContact O-CB 3.12Å; L106-T109 PolarHBondContact O-N 3.39Å; M107-T109 PolarHBondContact O-N 3.42Å; T109-F112 WeakPolarHBondContact O-CB 3.41Å; T109-F112 PolarHBondContact O-N 3.2Å; T109-F113 HydrophobicContact CG2-CD2 4.06Å; T109-F113 HydrophobicContact CG2-CE2 3.88Å; T109-F113 VanDerWaalsContact O-CD2 3.27Å; T109-F113 WeakPolarHBondContact O-CD2 3.35Å; T109-F113 PolarHBondContact O-N 3.35Å; T109-F113 VanDerWaalsContact O-N 3.17Å
110	A	98.4	Very high	97	Very high	0 Å²	0	37.7 Å²	37.7	0%	0	19%	0.192	C	C	.	.	H	α-helix	trans	-60.5	-46	174.4	0	0	0	0	0	112.5	S94 F97 L98 L106 M107 Q108 F112 F113 F114	S94-A110 WeakPolarHBondContact CB-O 3.34Å; S94-A110 PolarHBondContact OG-O 3.07Å; F97-A110 HydrophobicContact CB-CB 3.74Å; L98-A110 HydrophobicContact CD2-CB 3.79Å; L98-A110 HydrophobicContact CG-CB 3.78Å; L106-A110 PolarHBondContact O-N 3.15Å; M107-A110 WeakPolarHBondContact O-CA 3.43Å; M107-A110 WeakPolarHBondContact O-CB 3.28Å; M107-A110 PolarHBondContact O-N 3.46Å; M107-A110 VanDerWaalsContact O-N 3.07Å; Q108-A110 VanDerWaalsContact C-N 3.34Å; A110-F112 VanDerWaalsContact C-N 3.34Å; A110-F112 PolarHBondContact O-N 3.23Å; A110-F113 PolarHBondContact O-N 3.04Å; A110-F114 PolarHBondContact O-N 3.37Å
111	E	98.3	Very high	96.8	Very high	6 Å²	6	34.2 Å²	34.2	3%	0.028	18%	0.177	C	C	.	.	H	α-helix	trans	-63.6	-37.3	177	-69.1	-56.6	149.2	0	0	112.2	I56 V59 W60 M107 Q108 F113 F114 G115	I56-E111 HydrophobicContact CG2-CG 3.58Å; V59-E111 HydrophobicContact CB-CB 4.08Å; V59-E111 HydrophobicContact CG1-CB 4.35Å; W60-E111 HydrophobicContact CB-CB 4.31Å; W60-E111 WeakPolarHBondContact CB-OE2 3.36Å; M107-E111 WeakPolarHBondContact O-CG 3.49Å; M107-E111 PolarHBondContact O-N 3.24Å; Q108-E111 PolarHBondContact O-N 2.88Å; E111-F113 PolarHBondContact O-N 2.99Å; E111-F114 PolarHBondContact O-N 3.39Å; E111-G115 PolarHBondContact O-N 3.33Å
112	F	98.6	Very high	96.4	Very high	88 Å²	88	36.4 Å²	36.4	39%	0.386	19%	0.188	S	C	.	.	H	α-helix	trans	-58.3	-49.1	173.8	172.7	-90.1	0	0	0	111.6	V59 S63 Q108 T109 A110 F114 G115 V116	V59-F112 HydrophobicContact CG1-CB 3.98Å; S63-F112 PolarHBondContact OG-O 3.34Å; Q108-F112 PolarHBondContact O-N 3.48Å; T109-F112 WeakPolarHBondContact O-CB 3.41Å; T109-F112 PolarHBondContact O-N 3.2Å; A110-F112 VanDerWaalsContact C-N 3.34Å; A110-F112 PolarHBondContact O-N 3.23Å; F112-F114 VanDerWaalsContact C-N 3.28Å; F112-F114 PolarHBondContact O-N 3.36Å; F112-G115 PolarHBondContact O-N 2.88Å; F112-G115 VanDerWaalsContact O-N 3.17Å; F112-V116 HydrophobicContact CE1-CG2 4.18Å; F112-V116 HydrophobicContact CZ-CG2 4.5Å; F112-V116 PolarHBondContact O-N 3.08Å
113	F	98.5	Very high	96.1	Very high	57 Å²	57	31.6 Å²	31.6	25%	0.25	17%	0.165	C	C	.	.	H	α-helix	trans	-66.6	-31.8	177.1	-80.5	-74.1	0	0	0	112.1	A90 T93 F97 T109 A110 E111 G115 V116 V117	A90-F113 HydrophobicContact CB-CD1 4.23Å; T93-F113 HydrophobicContact CG2-CD1 4.04Å; T93-F113 HydrophobicContact CG2-CD2 3.67Å; T93-F113 HydrophobicContact CG2-CE1 3.95Å; T93-F113 HydrophobicContact CG2-CE2 3.6Å; T93-F113 HydrophobicContact CG2-CG 3.91Å; T93-F113 HydrophobicContact CG2-CZ 3.74Å; F97-F113 HydrophobicContact CD2-CD2 4.24Å; F97-F113 HydrophobicContact CD2-CE2 4.45Å; F97-F113 HydrophobicContact CE2-CD2 4.11Å; F97-F113 AromaticContact CE2-CE2 3.86Å; F97-F113 HydrophobicContact CE2-CE2 3.86Å; T109-F113 HydrophobicContact CG2-CD2 4.06Å; T109-F113 HydrophobicContact CG2-CE2 3.88Å; T109-F113 VanDerWaalsContact O-CD2 3.27Å; T109-F113 WeakPolarHBondContact O-CD2 3.35Å; T109-F113 PolarHBondContact O-N 3.35Å; T109-F113 VanDerWaalsContact O-N 3.17Å; A110-F113 PolarHBondContact O-N 3.04Å; E111-F113 PolarHBondContact O-N 2.99Å; F113-G115 VanDerWaalsContact C-N 3.31Å; F113-G115 PolarHBondContact O-N 3.29Å; F113-V116 WeakPolarHBondContact O-CB 3.39Å; F113-V116 PolarHBondContact O-N 3.25Å; F113-V117 WeakPolarHBondContact O-CG2 3.23Å; F113-V117 PolarHBondContact O-N 3.1Å
114	F	97.8	Very high	95.8	Very high	29 Å²	29	30.5 Å²	30.5	13%	0.127	15%	0.151	C	C	.	.	H	α-helix	trans	-68.2	-30.7	173.4	-162	-113.4	0	0	0	112.6	W60 F91 A110 E111 F112 V117 S118	W60-F114 AromaticContact CD1-CD1 3.51Å; W60-F114 HydrophobicContact CG-CD1 4.36Å; W60-F114 AromaticContact NE1-CD1 3.76Å; F91-F114 HydrophobicContact CE2-CD2 4.47Å; F91-F114 AromaticContact CE2-CE2 3.92Å; F91-F114 HydrophobicContact CE2-CE2 3.92Å; F91-F114 HydrophobicContact CZ-CE2 4.4Å; A110-F114 PolarHBondContact O-N 3.37Å; E111-F114 PolarHBondContact O-N 3.39Å; F112-F114 VanDerWaalsContact C-N 3.28Å; F112-F114 PolarHBondContact O-N 3.36Å; F114-V117 HydrophobicContact CD2-CB 4.38Å; F114-V117 HydrophobicContact CD2-CG1 4.45Å; F114-V117 HydrophobicContact CE2-CG1 4.45Å; F114-V117 WeakPolarHBondContact O-CB 3.48Å; F114-V117 PolarHBondContact O-N 3.24Å; F114-S118 PolarHBondContact O-N 2.95Å; F114-S118 PolarHBondContact O-OG 3.45Å
115	G	98.2	Very high	95.3	Very high	0 Å²	0	31.7 Å²	31.7	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-63.6	-39.8	168.1	0	0	0	0	0	112.6	S63 E111 F112 F113 S118 A119	S63-G115 WeakPolarHBondContact OG-CA 3.43Å; E111-G115 PolarHBondContact O-N 3.33Å; F112-G115 PolarHBondContact O-N 2.88Å; F112-G115 VanDerWaalsContact O-N 3.17Å; F113-G115 VanDerWaalsContact C-N 3.31Å; F113-G115 PolarHBondContact O-N 3.29Å; G115-S118 WeakPolarHBondContact O-CB 3.45Å; G115-S118 PolarHBondContact O-N 3.44Å; G115-A119 PolarHBondContact O-N 3.37Å
116	V	98	Very high	94.8	Very high	17 Å²	17	26.1 Å²	26.1	10%	0.103	13%	0.13	C	C	.	.	H	α-helix	trans	-63.2	-42.1	172.5	179.8	0	0	0	0	111.2	T67 L86 A90 F112 F113 S118 A119 T120	T67-V116 HydrophobicContact CG2-CG2 3.87Å; L86-V116 HydrophobicContact CG-CG1 4.46Å; A90-V116 HydrophobicContact CB-CB 4.08Å; A90-V116 HydrophobicContact CB-CG1 3.81Å; F112-V116 HydrophobicContact CE1-CG2 4.18Å; F112-V116 HydrophobicContact CZ-CG2 4.5Å; F112-V116 PolarHBondContact O-N 3.08Å; F113-V116 WeakPolarHBondContact O-CB 3.39Å; F113-V116 PolarHBondContact O-N 3.25Å; V116-S118 VanDerWaalsContact C-N 3.29Å; V116-S118 PolarHBondContact O-N 3.23Å; V116-A119 PolarHBondContact O-N 3.25Å; V116-T120 HydrophobicContact CG1-CG2 4.12Å; V116-T120 WeakPolarHBondContact O-CB 3.29Å; V116-T120 VanDerWaalsContact O-CG2 3.27Å; V116-T120 WeakPolarHBondContact O-CG2 3.47Å; V116-T120 PolarHBondContact O-N 3.09Å; V116-T120 PolarHBondContact O-OG1 3.46Å
117	V	97.3	Very high	94.4	Very high	2 Å²	2	23.8 Å²	23.8	1%	0.012	12%	0.117	C	C	.	.	H	α-helix	trans	-55	-47.8	173.2	167.1	0	0	0	0	110.5	H87 A90 F91 F113 F114 A119 T120 E121	H87-V117 VanDerWaalsContact CE1-CG1 3.5Å; H87-V117 WeakPolarHBondContact CE1-CG1 3.39Å; H87-V117 PolarHBondContact CE1-O 3.33Å; H87-V117 PolarHBondContact ND1-O 3.25Å; A90-V117 HydrophobicContact CB-CG2 3.99Å; F91-V117 VanDerWaalsContact CA-CG2 3.43Å; F91-V117 HydrophobicContact CB-CG2 3.69Å; F91-V117 HydrophobicContact CD2-CB 4.32Å; F91-V117 HydrophobicContact CD2-CG1 3.54Å; F91-V117 HydrophobicContact CD2-CG2 3.79Å; F91-V117 HydrophobicContact CE2-CG1 4.05Å; F91-V117 HydrophobicContact CG-CG2 4.14Å; F91-V117 VanDerWaalsContact N-CG2 3.32Å; F113-V117 WeakPolarHBondContact O-CG2 3.23Å; F113-V117 PolarHBondContact O-N 3.1Å; F114-V117 HydrophobicContact CD2-CB 4.38Å; F114-V117 HydrophobicContact CD2-CG1 4.45Å; F114-V117 HydrophobicContact CE2-CG1 4.45Å; F114-V117 WeakPolarHBondContact O-CB 3.48Å; F114-V117 PolarHBondContact O-N 3.24Å; V117-A119 PolarHBondContact O-N 2.67Å; V117-T120 WeakPolarHBondContact CA-OG1 3.24Å; V117-T120 PolarHBondContact O-N 3.41Å; V117-T120 PolarHBondContact O-OG1 3.05Å; V117-E121 PolarHBondContact O-N 2.85Å
118	S	95.7	Very high	93.8	Very high	12 Å²	12	23.8 Å²	23.8	8%	0.084	12%	0.117	C	C	.	.	H	α-helix	trans	-63	-43.3	-178.7	-54.7	0	0	0	0	111.6	W60 F114 G115 V116	W60-S118 PolarHBondContact NE1-OG 3.01Å; F114-S118 PolarHBondContact O-N 2.95Å; F114-S118 PolarHBondContact O-OG 3.45Å; G115-S118 WeakPolarHBondContact O-CB 3.45Å; G115-S118 PolarHBondContact O-N 3.44Å; V116-S118 VanDerWaalsContact C-N 3.29Å; V116-S118 PolarHBondContact O-N 3.23Å
119	A	95.7	Very high	93.1	Very high	0 Å²	0	24.3 Å²	24.3	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-64.6	-40.9	175.7	0	0	0	0	0	113	Y64 T67 L68 V71 G115 V116 V117	Y64-A119 HydrophobicContact CD2-CB 4.09Å; Y64-A119 HydrophobicContact CE2-CB 4.25Å; T67-A119 WeakPolarHBondContact OG1-CB 3.48Å; L68-A119 HydrophobicContact CB-CB 4.45Å; V71-A119 HydrophobicContact CB-CB 4.16Å; V71-A119 HydrophobicContact CG1-CB 4.34Å; V71-A119 WeakPolarHBondContact CG1-O 3.48Å; V71-A119 HydrophobicContact CG2-CB 4.01Å; G115-A119 PolarHBondContact O-N 3.37Å; V116-A119 PolarHBondContact O-N 3.25Å; V117-A119 PolarHBondContact O-N 2.67Å
120	T	95.3	Very high	92.4	Very high	1 Å²	1	23 Å²	23	1%	0.006	11%	0.11	C	C	.	.	H	α-helix	trans	-78.6	-16.7	-176.2	53.6	0	0	0	0	113.8	V71 V83 L86 H87 V116 V117 I122 A123	V71-T120 HydrophobicContact CG1-CG2 3.84Å; V71-T120 HydrophobicContact CG2-CG2 3.92Å; V83-T120 HydrophobicContact CG1-CG2 3.8Å; L86-T120 HydrophobicContact CD2-CG2 4Å; L86-T120 HydrophobicContact CG-CG2 4.18Å; H87-T120 VanDerWaalsContact CA-OG1 3.29Å; H87-T120 WeakPolarHBondContact CA-OG1 3.22Å; H87-T120 VanDerWaalsContact CB-OG1 3.28Å; H87-T120 WeakPolarHBondContact CB-OG1 3.31Å; H87-T120 PolarHBondContact ND1-OG1 3.34Å; V116-T120 HydrophobicContact CG1-CG2 4.12Å; V116-T120 WeakPolarHBondContact O-CB 3.29Å; V116-T120 VanDerWaalsContact O-CG2 3.27Å; V116-T120 WeakPolarHBondContact O-CG2 3.47Å; V116-T120 PolarHBondContact O-N 3.09Å; V116-T120 PolarHBondContact O-OG1 3.46Å; V117-T120 WeakPolarHBondContact CA-OG1 3.24Å; V117-T120 PolarHBondContact O-N 3.41Å; V117-T120 PolarHBondContact O-OG1 3.05Å; T120-I122 PolarHBondContact O-N 3.41Å; T120-A123 VanDerWaalsContact O-CB 3.31Å; T120-A123 WeakPolarHBondContact O-CB 3.23Å; T120-A123 PolarHBondContact O-N 2.93Å
121	E	92.2	Very high	91.7	Very high	59 Å²	59	25.3 Å²	25.3	28%	0.276	12%	0.121	S	C	.	.	H	α-helix	trans	-58.3	-31.7	174.7	-173.1	176	-170.7	0	0	112.4	V117 A123 Y124 F125	V117-E121 PolarHBondContact O-N 2.85Å; E121-A123 PolarHBondContact O-N 3.38Å; E121-A123 VanDerWaalsContact O-N 3.16Å; E121-Y124 VanDerWaalsContact O-CB 3.31Å; E121-Y124 WeakPolarHBondContact O-CB 3.4Å; E121-Y124 PolarHBondContact O-N 3.44Å; E121-F125 HydrophobicContact CG-CE2 4.37Å
122	I	85.3	Confident	91	Very high	49 Å²	49	25.7 Å²	25.7	25%	0.251	12%	0.124	S	C	.	.	H	α-helix	trans	-57.5	-34	177.3	-61.6	173.8	0	0	0	111.4	L68 T120 Y124 F125 A126	L68-I122 HydrophobicContact CD1-CD1 3.22Å; T120-I122 PolarHBondContact O-N 3.41Å; I122-Y124 VanDerWaalsContact C-N 3.28Å; I122-Y124 PolarHBondContact O-N 3.36Å; I122-F125 PolarHBondContact O-N 2.96Å; I122-A126 WeakPolarHBondContact O-CB 3.49Å; I122-A126 PolarHBondContact O-N 3.46Å
123	A	87.4	Confident	90.3	Very high	0 Å²	0	23.4 Å²	23.4	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-64.5	-31.5	178.4	0	0	0	0	0	112.5	T75 V83 I84 T120 E121 A126 Y127	T75-A123 HydrophobicContact CG2-CB 3.74Å; V83-A123 HydrophobicContact CB-CB 4Å; V83-A123 HydrophobicContact CG1-CB 3.65Å; I84-A123 HydrophobicContact CG1-CB 4.33Å; T120-A123 VanDerWaalsContact O-CB 3.31Å; T120-A123 WeakPolarHBondContact O-CB 3.23Å; T120-A123 PolarHBondContact O-N 2.93Å; E121-A123 PolarHBondContact O-N 3.38Å; E121-A123 VanDerWaalsContact O-N 3.16Å; A123-A126 PolarHBondContact O-N 3.39Å; A123-Y127 VanDerWaalsContact O-CB 3.25Å; A123-Y127 WeakPolarHBondContact O-CB 3.46Å; A123-Y127 PolarHBondContact O-N 3.02Å
124	Y	89.3	Confident	89.4	Confident	10 Å²	10	25 Å²	25	4%	0.039	14%	0.136	C	C	.	.	H	α-helix	trans	-62.2	-48.7	177.4	169.5	-102.6	0	0	0	111.4	L20 F23 E121 I122 C144 T148	L20-Y124 HydrophobicContact CD1-CD2 3.59Å; L20-Y124 HydrophobicContact CD1-CE2 3.49Å; L20-Y124 VanDerWaalsContact CD1-CE2 3.49Å; L20-Y124 HydrophobicContact CG-CD2 4.23Å; L20-Y124 HydrophobicContact CG-CE2 3.65Å; L20-Y124 WeakPolarHBondContact O-CE2 3.21Å; F23-Y124 AromaticContact CD1-CD2 3.54Å; F23-Y124 HydrophobicContact CD1-CD2 3.54Å; F23-Y124 AromaticContact CD1-CE2 3.65Å; F23-Y124 HydrophobicContact CD1-CE2 3.65Å; F23-Y124 AromaticContact CE1-CD2 3.58Å; F23-Y124 HydrophobicContact CE1-CD2 3.58Å; F23-Y124 HydrophobicContact CE1-CE2 4.14Å; F23-Y124 HydrophobicContact CE1-CG 4.37Å; E121-Y124 VanDerWaalsContact O-CB 3.31Å; E121-Y124 WeakPolarHBondContact O-CB 3.4Å; E121-Y124 PolarHBondContact O-N 3.44Å; I122-Y124 VanDerWaalsContact C-N 3.28Å; I122-Y124 PolarHBondContact O-N 3.36Å; Y124-C144 HydrophobicContact CE1-CB 4.37Å; Y124-C144 PolarHBondContact OH-O 3.5Å; Y124-T148 HydrophobicContact CE1-CG2 3.78Å
125	F	86.5	Confident	88.8	Confident	53 Å²	53	31.4 Å²	31.4	23%	0.232	17%	0.166	C	C	.	.	H	α-helix	trans	-72.1	-36.2	178.3	-66.9	-66	0	0	0	112.2	E121 I122 Y127 I128 Y129 R145	E121-F125 HydrophobicContact CG-CE2 4.37Å; I122-F125 PolarHBondContact O-N 2.96Å; F125-Y127 VanDerWaalsContact C-N 3.31Å; F125-Y127 PolarHBondContact O-N 2.83Å; F125-I128 HydrophobicContact CD1-CD1 4.34Å; F125-I128 WeakPolarHBondContact O-CB 3.47Å; F125-I128 PolarHBondContact O-N 3.02Å; F125-Y129 WeakPolarHBondContact O-CD2 3.36Å; F125-Y129 WeakPolarHBondContact O-CE2 3.28Å; F125-R145 HydrophobicContact CD1-CG 4.33Å; F125-R145 HydrophobicContact CE1-CG 3.7Å
126	A	87.1	Confident	88.3	Confident	17 Å²	17	33.5 Å²	33.5	14%	0.14	18%	0.175	C	C	.	.	H	α-helix	trans	-67.1	-31.4	177.8	0	0	0	0	0	112.9	Y80 I122 A123 I128 Y129 M198	Y80-A126 HydrophobicContact CD1-CB 3.96Å; Y80-A126 HydrophobicContact CE1-CB 3.67Å; I122-A126 WeakPolarHBondContact O-CB 3.49Å; I122-A126 PolarHBondContact O-N 3.46Å; A123-A126 PolarHBondContact O-N 3.39Å; A126-I128 PolarHBondContact O-N 3.1Å; A126-Y129 PolarHBondContact O-N 2.86Å; A126-M198 HydrophobicContact CB-CE 4.34Å
127	Y	88.4	Confident	87.6	Confident	1 Å²	1	35 Å²	35	0%	0.004	18%	0.179	C	C	.	.	H	α-helix	trans	-59.9	-32.1	177.8	179.9	-85.1	0	0	0	113.2	L20 I84 A123 F125 Y129 S130 M131 L191 P192 P194	L20-Y127 HydrophobicContact CD1-CD1 3.73Å; L20-Y127 HydrophobicContact CD1-CE1 4.12Å; L20-Y127 HydrophobicContact CD1-CG 4.45Å; L20-Y127 HydrophobicContact CD2-CD1 3.73Å; L20-Y127 HydrophobicContact CD2-CE1 4.24Å; L20-Y127 HydrophobicContact CG-CD1 4.31Å; I84-Y127 HydrophobicContact CD1-CD2 3.6Å; I84-Y127 HydrophobicContact CD1-CE2 4.32Å; I84-Y127 HydrophobicContact CD1-CG 3.77Å; A123-Y127 VanDerWaalsContact O-CB 3.25Å; A123-Y127 WeakPolarHBondContact O-CB 3.46Å; A123-Y127 PolarHBondContact O-N 3.02Å; F125-Y127 VanDerWaalsContact C-N 3.31Å; F125-Y127 PolarHBondContact O-N 2.83Å; Y127-Y129 VanDerWaalsContact C-N 3.26Å; Y127-Y129 PolarHBondContact O-N 2.93Å; Y127-S130 PolarHBondContact O-N 3Å; Y127-S130 PolarHBondContact O-OG 3.45Å; Y127-M131 HydrophobicContact CD1-CG 4.09Å; Y127-M131 HydrophobicContact CE1-CB 4.25Å; Y127-M131 HydrophobicContact CE1-CG 3.52Å; Y127-M131 HydrophobicContact CE2-CG 3.99Å; Y127-M131 VanDerWaalsContact CZ-CG 3.44Å; Y127-M131 PolarHBondContact O-N 3.4Å; Y127-L191 HydrophobicContact CE1-CD2 4Å; Y127-P192 WeakPolarHBondContact OH-CD 3.41Å; Y127-P192 WeakPolarHBondContact OH-CG 3.22Å; Y127-P192 PolarHBondContact OH-O 2.9Å; Y127-P194 HydrophobicContact CD2-CG 3.86Å; Y127-P194 HydrophobicContact CE2-CG 3.57Å
128	I	86	Confident	87	Confident	2 Å²	2	42.9 Å²	42.9	1%	0.01	22%	0.216	C	C	.	.	H	α-helix	trans	-54.9	-47	177.6	-61.7	168.3	0	0	0	110.4	L20 F125 A126 S130 M131 V132 V140 C144	L20-I128 HydrophobicContact CD2-CG1 3.56Å; F125-I128 HydrophobicContact CD1-CD1 4.34Å; F125-I128 WeakPolarHBondContact O-CB 3.47Å; F125-I128 PolarHBondContact O-N 3.02Å; A126-I128 PolarHBondContact O-N 3.1Å; I128-S130 VanDerWaalsContact C-N 3.29Å; I128-S130 PolarHBondContact O-N 3.2Å; I128-M131 PolarHBondContact O-N 2.82Å; I128-V132 WeakPolarHBondContact O-CB 3.29Å; I128-V132 WeakPolarHBondContact O-CG2 3.5Å; I128-V132 PolarHBondContact O-N 2.8Å; I128-V140 HydrophobicContact CG2-CB 4.04Å; I128-V140 HydrophobicContact CG2-CG1 3.62Å; I128-C144 HydrophobicContact CD1-CB 3.48Å; I128-C144 VanDerWaalsContact CD1-CB 3.48Å; I128-C144 HydrophobicContact CG1-CB 4.37Å
129	Y	83.7	Confident	86.7	Confident	65 Å²	65	47.1 Å²	47.1	26%	0.255	23%	0.233	S	C	.	.	H	α-helix	trans	-77.9	-12.6	-174.2	-52.4	-67.7	0	0	0	113.5	F125 A126 Y127 Y137 S141	F125-Y129 WeakPolarHBondContact O-CD2 3.36Å; F125-Y129 WeakPolarHBondContact O-CE2 3.28Å; A126-Y129 PolarHBondContact O-N 2.86Å; Y127-Y129 VanDerWaalsContact C-N 3.26Å; Y127-Y129 PolarHBondContact O-N 2.93Å; Y129-Y137 AromaticContact CD1-CD1 3.82Å; Y129-Y137 HydrophobicContact CD1-CD1 3.82Å; Y129-Y137 AromaticContact CD1-CD2 3.75Å; Y129-Y137 HydrophobicContact CD1-CD2 3.75Å; Y129-Y137 HydrophobicContact CD1-CE1 4.03Å; Y129-Y137 HydrophobicContact CD1-CE2 4Å; Y129-Y137 AromaticContact CD1-CG 3.68Å; Y129-Y137 HydrophobicContact CD1-CG 3.68Å; Y129-Y137 HydrophobicContact CE1-CD1 4.49Å; Y129-Y137 HydrophobicContact CE1-CD2 4.23Å; Y129-Y137 HydrophobicContact CE1-CG 4.05Å; Y129-Y137 PolarHBondContact O-OH 2.8Å; Y129-Y137 VanDerWaalsContact O-OH 3.08Å; Y129-S141 WeakPolarHBondContact CE1-OG 3.42Å; Y129-S141 VanDerWaalsContact CZ-OG 3.31Å; Y129-S141 PolarHBondContact OH-OG 3.34Å
130	S	82.8	Confident	86.5	Confident	16 Å²	16	47.1 Å²	47.1	11%	0.112	23%	0.233	C	C	.	.	H	α-helix	trans	-92.9	-16	175.8	68.8	0	0	0	0	113.7	Y127 I128 P194	Y127-S130 PolarHBondContact O-N 3Å; Y127-S130 PolarHBondContact O-OG 3.45Å; I128-S130 VanDerWaalsContact C-N 3.29Å; I128-S130 PolarHBondContact O-N 3.2Å; S130-P194 WeakPolarHBondContact OG-CB 3.38Å; S130-P194 WeakPolarHBondContact OG-CG 3.2Å
131	M	83.4	Confident	86.3	Confident	47 Å²	47	47.5 Å²	47.5	23%	0.232	24%	0.236	C	C	.	.	H	α-helix	trans	-109.4	-18.1	-175.4	-75.9	-59.5	-49.4	0	0	114.9	P16 Y127 I128 P192 P194	P16-M131 HydrophobicContact CB-CE 4.11Å; P16-M131 HydrophobicContact CG-CE 3.87Å; Y127-M131 HydrophobicContact CD1-CG 4.09Å; Y127-M131 HydrophobicContact CE1-CB 4.25Å; Y127-M131 HydrophobicContact CE1-CG 3.52Å; Y127-M131 HydrophobicContact CE2-CG 3.99Å; Y127-M131 VanDerWaalsContact CZ-CG 3.44Å; Y127-M131 PolarHBondContact O-N 3.4Å; I128-M131 PolarHBondContact O-N 2.82Å; M131-P192 HydrophobicContact CE-CB 3.85Å; M131-P192 HydrophobicContact CE-CG 3.41Å; M131-P192 VanDerWaalsContact CE-CG 3.41Å; M131-P192 HydrophobicContact SD-CG 4.27Å; M131-P194 HydrophobicContact CG-CB 4.48Å; M131-P194 HydrophobicContact CG-CG 4.09Å; M131-P194 VanDerWaalsContact SD-CA 3.54Å; M131-P194 HydrophobicContact SD-CB 3.91Å; M131-P194 HydrophobicContact SD-CG 3.83Å
132	V	84.2	Confident	86.2	Confident	14 Å²	14	47.5 Å²	47.5	9%	0.085	24%	0.242	C	C	.	.	S	Bend	trans	-115	152.3	-170.4	-179.5	0	0	0	0	109.3	W13 I128 H136 Y137 V140	W13-V132 HydrophobicContact CB-CG1 4.3Å; W13-V132 HydrophobicContact CB-CG2 4.39Å; I128-V132 WeakPolarHBondContact O-CB 3.29Å; I128-V132 WeakPolarHBondContact O-CG2 3.5Å; I128-V132 PolarHBondContact O-N 2.8Å; V132-H136 HydrophobicContact CG1-CB 3.37Å; V132-Y137 HydrophobicContact CB-CD1 4.39Å; V132-Y137 HydrophobicContact CB-CE1 4.42Å; V132-Y137 HydrophobicContact CG1-CD1 4.36Å; V132-Y137 WeakPolarHBondContact O-CE1 3.45Å; V132-V140 HydrophobicContact CG1-CG2 3.97Å; V132-V140 HydrophobicContact CG2-CG1 4.25Å; V132-V140 HydrophobicContact CG2-CG2 4.26Å
133	S	83.2	Confident	86.6	Confident	41 Å²	41	50.3 Å²	50.3	29%	0.287	25%	0.25	S	S	.	.			trans	-76.5	151.7	171.9	61.9	0	0	0	0	110.9	E135 H136 Y137	S133-E135 PolarHBondContact O-N 3.33Å; S133-H136 PolarHBondContact O-N 3.4Å; S133-H136 PolarHBondContact OG-ND1 3.1Å; S133-Y137 WeakPolarHBondContact O-CD1 3.41Å
134	P	80.9	Confident	86.9	Confident	91 Å²	91	50.3 Å²	50.3	59%	0.591	25%	0.25	S	S	*	.	G	3₁₀ helix	trans	-51.9	-33.6	-179	-29.7	35.9	0	0	0	115.1	H136 Y137	P134-H136 PolarHBondContact O-N 3.35Å; P134-H136 VanDerWaalsContact O-N 3.09Å; P134-Y137 HydrophobicContact CB-CD2 4.17Å; P134-Y137 HydrophobicContact CB-CE2 3.94Å; P134-Y137 HydrophobicContact CG-CE2 4.02Å; P134-Y137 WeakPolarHBondContact O-CB 3.35Å; P134-Y137 PolarHBondContact O-N 3.25Å; P134-Y137 VanDerWaalsContact O-N 3.15Å
135	E	84.6	Confident	87	Confident	163 Å²	163	55.9 Å²	55.9	76%	0.762	27%	0.272	S	S	*	.	G	3₁₀ helix	trans	-53.5	-28.1	175.6	-62.7	149.8	-141	0	0	113.7	S133	S133-E135 PolarHBondContact O-N 3.33Å
136	H	86.8	Confident	87.3	Confident	43 Å²	43	56.7 Å²	56.7	20%	0.199	28%	0.283	C	S	.	.	G	3₁₀ helix	trans	-109.2	-1.2	-175.2	-59.8	92.3	0	0	0	113.1	W13 V132 S133 P134 Q138 K139 V140	W13-H136 AromaticContact CD1-CE1 3.93Å; W13-H136 AromaticContact CD1-NE2 3.82Å; W13-H136 AromaticContact CE2-CD2 3.48Å; W13-H136 VanDerWaalsContact CE2-CD2 3.48Å; W13-H136 AromaticContact CE2-NE2 3.74Å; W13-H136 AromaticContact CZ2-CD2 3.78Å; W13-H136 AromaticContact NE1-CD2 3.47Å; W13-H136 PolarHBondContact NE1-CD2 3.27Å; W13-H136 AromaticContact NE1-CE1 3.8Å; W13-H136 AromaticContact NE1-NE2 3.24Å; W13-H136 PolarHBondContact NE1-NE2 3.02Å; V132-H136 HydrophobicContact CG1-CB 3.37Å; S133-H136 PolarHBondContact O-N 3.4Å; S133-H136 PolarHBondContact OG-ND1 3.1Å; P134-H136 PolarHBondContact O-N 3.35Å; P134-H136 VanDerWaalsContact O-N 3.09Å; H136-Q138 PolarHBondContact O-N 3.35Å; H136-K139 PolarHBondContact O-N 2.93Å; H136-V140 HydrophobicContact CB-CG2 4.27Å; H136-V140 WeakPolarHBondContact O-CG2 3.47Å; H136-V140 PolarHBondContact O-N 2.92Å
137	Y	84.3	Confident	87.8	Confident	48 Å²	48	58 Å²	58	19%	0.188	29%	0.288	C	S	.	.	H	α-helix	trans	-54.8	-50.3	-176.7	-77	-4.5	0	0	0	112.8	Y129 V132 S133 P134 K139 S141 L394	Y129-Y137 AromaticContact CD1-CD1 3.82Å; Y129-Y137 HydrophobicContact CD1-CD1 3.82Å; Y129-Y137 AromaticContact CD1-CD2 3.75Å; Y129-Y137 HydrophobicContact CD1-CD2 3.75Å; Y129-Y137 HydrophobicContact CD1-CE1 4.03Å; Y129-Y137 HydrophobicContact CD1-CE2 4Å; Y129-Y137 AromaticContact CD1-CG 3.68Å; Y129-Y137 HydrophobicContact CD1-CG 3.68Å; Y129-Y137 HydrophobicContact CE1-CD1 4.49Å; Y129-Y137 HydrophobicContact CE1-CD2 4.23Å; Y129-Y137 HydrophobicContact CE1-CG 4.05Å; Y129-Y137 PolarHBondContact O-OH 2.8Å; Y129-Y137 VanDerWaalsContact O-OH 3.08Å; V132-Y137 HydrophobicContact CB-CD1 4.39Å; V132-Y137 HydrophobicContact CB-CE1 4.42Å; V132-Y137 HydrophobicContact CG1-CD1 4.36Å; V132-Y137 WeakPolarHBondContact O-CE1 3.45Å; S133-Y137 WeakPolarHBondContact O-CD1 3.41Å; P134-Y137 HydrophobicContact CB-CD2 4.17Å; P134-Y137 HydrophobicContact CB-CE2 3.94Å; P134-Y137 HydrophobicContact CG-CE2 4.02Å; P134-Y137 WeakPolarHBondContact O-CB 3.35Å; P134-Y137 PolarHBondContact O-N 3.25Å; P134-Y137 VanDerWaalsContact O-N 3.15Å; Y137-K139 VanDerWaalsContact C-N 3.34Å; Y137-K139 PolarHBondContact O-N 2.87Å; Y137-S141 WeakPolarHBondContact O-CB 3.37Å; Y137-S141 PolarHBondContact O-N 2.96Å; Y137-S141 PolarHBondContact O-OG 3.44Å; Y137-L394 HydrophobicContact CD2-CD1 4.44Å; Y137-L394 HydrophobicContact CE2-CD1 4.43Å
138	Q	84.3	Confident	88.1	Confident	168 Å²	168	58.6 Å²	58.6	79%	0.785	29%	0.291	S	S	*	.	H	α-helix	trans	-59.3	-47.9	-179.5	-174.8	179.6	6.5	0	0	111.1	H136 S142	H136-Q138 PolarHBondContact O-N 3.35Å; Q138-S142 WeakPolarHBondContact O-CB 3.4Å; Q138-S142 PolarHBondContact O-N 2.91Å; Q138-S142 PolarHBondContact O-OG 3.01Å
139	K	89.8	Confident	88.4	Confident	101 Å²	101	62.1 Å²	62.1	44%	0.439	31%	0.31	S	S	.	.	H	α-helix	trans	-65.1	-48.5	-176.4	-172.6	175.7	-177.1	178.5	0	112	W13 H136 Y137 S142 Y143	W13-K139 HydrophobicContact CH2-CD 4.33Å; H136-K139 PolarHBondContact O-N 2.93Å; Y137-K139 VanDerWaalsContact C-N 3.34Å; Y137-K139 PolarHBondContact O-N 2.87Å; K139-S142 WeakPolarHBondContact O-CB 3.28Å; K139-S142 PolarHBondContact O-N 3.16Å; K139-Y143 HydrophobicContact CD-CE2 4.18Å; K139-Y143 WeakPolarHBondContact CE-OH 3.4Å; K139-Y143 HydrophobicContact CG-CD2 4.3Å; K139-Y143 HydrophobicContact CG-CE2 3.6Å; K139-Y143 WeakPolarHBondContact O-CD2 3.39Å; K139-Y143 PolarHBondContact O-N 3.49Å
140	V	91.6	Very high	89	Confident	0 Å²	0	63 Å²	63	0%	0	32%	0.322	C	S	.	.	H	α-helix	trans	-70.2	-41	-178.9	179.5	0	0	0	0	111.3	W13 T17 I128 V132 H136 S142 Y143 C144	W13-V140 HydrophobicContact CE3-CG2 3.58Å; W13-V140 HydrophobicContact CZ3-CG2 3.73Å; T17-V140 HydrophobicContact CG2-CG1 3.78Å; T17-V140 HydrophobicContact CG2-CG2 4.26Å; I128-V140 HydrophobicContact CG2-CB 4.04Å; I128-V140 HydrophobicContact CG2-CG1 3.62Å; V132-V140 HydrophobicContact CG1-CG2 3.97Å; V132-V140 HydrophobicContact CG2-CG1 4.25Å; V132-V140 HydrophobicContact CG2-CG2 4.26Å; H136-V140 HydrophobicContact CB-CG2 4.27Å; H136-V140 WeakPolarHBondContact O-CG2 3.47Å; H136-V140 PolarHBondContact O-N 2.92Å; V140-S142 VanDerWaalsContact C-N 3.3Å; V140-S142 PolarHBondContact O-N 3.46Å; V140-Y143 PolarHBondContact O-N 2.95Å; V140-C144 WeakPolarHBondContact O-CB 3.26Å; V140-C144 PolarHBondContact O-N 3.35Å; V140-C144 PolarHBondContact O-SG 3.48Å
141	S	90.2	Very high	89.6	Confident	9 Å²	9	62.2 Å²	62.2	6%	0.063	32%	0.316	C	S	.	.	H	α-helix	trans	-61.4	-38.9	173.7	-67.6	0	0	0	0	112	Y129 Y137 R145	Y129-S141 WeakPolarHBondContact CE1-OG 3.42Å; Y129-S141 VanDerWaalsContact CZ-OG 3.31Å; Y129-S141 PolarHBondContact OH-OG 3.34Å; Y137-S141 WeakPolarHBondContact O-CB 3.37Å; Y137-S141 PolarHBondContact O-N 2.96Å; Y137-S141 PolarHBondContact O-OG 3.44Å; S141-R145 WeakPolarHBondContact O-CB 3.39Å; S141-R145 WeakPolarHBondContact O-CG 3.47Å; S141-R145 PolarHBondContact O-N 3.01Å
142	S	91.1	Very high	90.2	Very high	59 Å²	59	62 Å²	62	41%	0.413	31%	0.313	S	S	.	.	H	α-helix	trans	-61.3	-48.3	172	-70.2	0	0	0	0	111.8	Q138 K139 V140 C144 R145 S146	Q138-S142 WeakPolarHBondContact O-CB 3.4Å; Q138-S142 PolarHBondContact O-N 2.91Å; Q138-S142 PolarHBondContact O-OG 3.01Å; K139-S142 WeakPolarHBondContact O-CB 3.28Å; K139-S142 PolarHBondContact O-N 3.16Å; V140-S142 VanDerWaalsContact C-N 3.3Å; V140-S142 PolarHBondContact O-N 3.46Å; S142-C144 PolarHBondContact O-N 3.29Å; S142-R145 PolarHBondContact O-N 3.45Å; S142-S146 VanDerWaalsContact O-CB 3.28Å; S142-S146 WeakPolarHBondContact O-CB 3.5Å; S142-S146 PolarHBondContact O-N 3.04Å; S142-S146 PolarHBondContact O-OG 2.78Å
143	Y	93.5	Very high	90.7	Very high	108 Å²	108	63 Å²	63	42%	0.424	32%	0.32	S	S	.	.	H	α-helix	trans	-59.6	-46.8	177.3	-63.9	-28.9	0	0	0	112.7	T17 K139 V140 R145 S146 I147	T17-Y143 HydrophobicContact CG2-CD2 4.4Å; K139-Y143 HydrophobicContact CD-CE2 4.18Å; K139-Y143 WeakPolarHBondContact CE-OH 3.4Å; K139-Y143 HydrophobicContact CG-CD2 4.3Å; K139-Y143 HydrophobicContact CG-CE2 3.6Å; K139-Y143 WeakPolarHBondContact O-CD2 3.39Å; K139-Y143 PolarHBondContact O-N 3.49Å; V140-Y143 PolarHBondContact O-N 2.95Å; Y143-R145 VanDerWaalsContact C-N 3.34Å; Y143-R145 PolarHBondContact O-N 3.37Å; Y143-S146 PolarHBondContact O-N 3.05Å; Y143-I147 WeakPolarHBondContact O-CB 3.29Å; Y143-I147 WeakPolarHBondContact O-CG2 3.3Å; Y143-I147 PolarHBondContact O-N 3.02Å
144	C	93.9	Very high	91.3	Very high	0 Å²	0	63 Å²	63	0%	0	32%	0.322	C	S	.	.	H	α-helix	trans	-66.9	-33.3	-178.8	-63.9	0	0	0	0	112.7	Y124 I128 V140 S142 I147 T148	Y124-C144 HydrophobicContact CE1-CB 4.37Å; Y124-C144 PolarHBondContact OH-O 3.5Å; I128-C144 HydrophobicContact CD1-CB 3.48Å; I128-C144 VanDerWaalsContact CD1-CB 3.48Å; I128-C144 HydrophobicContact CG1-CB 4.37Å; V140-C144 WeakPolarHBondContact O-CB 3.26Å; V140-C144 PolarHBondContact O-N 3.35Å; V140-C144 PolarHBondContact O-SG 3.48Å; S142-C144 PolarHBondContact O-N 3.29Å; C144-I147 WeakPolarHBondContact O-CG2 3.25Å; C144-T148 VanDerWaalsContact O-CG2 3.29Å; C144-T148 WeakPolarHBondContact O-CG2 3.4Å; C144-T148 PolarHBondContact O-OG1 2.77Å
145	R	91.5	Very high	92.1	Very high	128 Å²	128	58.7 Å²	58.7	48%	0.483	29%	0.294	S	S	.	.	H	α-helix	trans	-77.6	-39.7	174.3	-75.5	-177	170.9	163.2	-1.6	112.7	F125 S141 S142 Y143 T148 L149	F125-R145 HydrophobicContact CD1-CG 4.33Å; F125-R145 HydrophobicContact CE1-CG 3.7Å; S141-R145 WeakPolarHBondContact O-CB 3.39Å; S141-R145 WeakPolarHBondContact O-CG 3.47Å; S141-R145 PolarHBondContact O-N 3.01Å; S142-R145 PolarHBondContact O-N 3.45Å; Y143-R145 VanDerWaalsContact C-N 3.34Å; Y143-R145 PolarHBondContact O-N 3.37Å; R145-T148 PolarHBondContact O-OG1 3.13Å; R145-L149 WeakPolarHBondContact O-CG 3.17Å; R145-L149 PolarHBondContact O-N 3.25Å
146	S	93.4	Very high	92.7	Very high	69 Å²	69	51 Å²	51	48%	0.483	26%	0.258	S	S	.	.	H	α-helix	trans	-64.9	-42.1	177.8	-67.7	0	0	0	0	111.3	S142 Y143 T148 L149 V150	S142-S146 VanDerWaalsContact O-CB 3.28Å; S142-S146 WeakPolarHBondContact O-CB 3.5Å; S142-S146 PolarHBondContact O-N 3.04Å; S142-S146 PolarHBondContact O-OG 2.78Å; Y143-S146 PolarHBondContact O-N 3.05Å; S146-T148 PolarHBondContact O-N 2.67Å; S146-L149 PolarHBondContact O-N 3.36Å; S146-V150 WeakPolarHBondContact O-CB 3.26Å; S146-V150 VanDerWaalsContact O-CG2 3.29Å; S146-V150 WeakPolarHBondContact O-CG2 3.28Å; S146-V150 PolarHBondContact O-N 3.36Å
147	I	96.5	Very high	93.1	Very high	46 Å²	46	52 Å²	52	24%	0.236	27%	0.267	C	S	.	.	H	α-helix	trans	-67.8	-36.7	-178.3	-162	65	0	0	0	112.4	C21 F25 Y143 C144 V150 A151	C21-I147 HydrophobicContact CB-CG2 4.15Å; F25-I147 HydrophobicContact CB-CD1 4.42Å; F25-I147 HydrophobicContact CB-CG1 3.83Å; F25-I147 HydrophobicContact CD2-CD1 3.74Å; F25-I147 HydrophobicContact CD2-CG1 3.95Å; F25-I147 HydrophobicContact CG-CD1 4.49Å; F25-I147 HydrophobicContact CG-CG1 4.37Å; Y143-I147 WeakPolarHBondContact O-CB 3.29Å; Y143-I147 WeakPolarHBondContact O-CG2 3.3Å; Y143-I147 PolarHBondContact O-N 3.02Å; C144-I147 WeakPolarHBondContact O-CG2 3.25Å; I147-V150 PolarHBondContact O-N 2.91Å; I147-A151 VanDerWaalsContact O-CB 3.25Å; I147-A151 WeakPolarHBondContact O-CB 3.41Å; I147-A151 PolarHBondContact O-N 3.48Å
148	T	94.4	Very high	93.7	Very high	12 Å²	12	52.5 Å²	52.5	7%	0.074	27%	0.273	C	S	.	.	H	α-helix	trans	-68.1	-39.1	176.8	53.7	0	0	0	0	111.6	M28 Y124 C144 R145 S146 A151 Y152	M28-T148 HydrophobicContact CG-CG2 3.75Å; Y124-T148 HydrophobicContact CE1-CG2 3.78Å; C144-T148 VanDerWaalsContact O-CG2 3.29Å; C144-T148 WeakPolarHBondContact O-CG2 3.4Å; C144-T148 PolarHBondContact O-OG1 2.77Å; R145-T148 PolarHBondContact O-OG1 3.13Å; S146-T148 PolarHBondContact O-N 2.67Å; T148-A151 PolarHBondContact O-N 3.31Å; T148-Y152 WeakPolarHBondContact O-CB 3.48Å; T148-Y152 PolarHBondContact O-N 2.93Å
149	L	93.2	Very high	94.3	Very high	77 Å²	77	44.5 Å²	44.5	40%	0.403	24%	0.235	S	C	.	.	H	α-helix	trans	-63.8	-47.2	172.9	-72.3	170.3	0	0	0	111.9	R145 S146 A151 Y152 T153 T318 A322	R145-L149 WeakPolarHBondContact O-CG 3.17Å; R145-L149 PolarHBondContact O-N 3.25Å; S146-L149 PolarHBondContact O-N 3.36Å; L149-A151 VanDerWaalsContact C-N 3.33Å; L149-A151 PolarHBondContact O-N 2.95Å; L149-Y152 PolarHBondContact O-N 3.33Å; L149-T153 WeakPolarHBondContact O-CB 3.44Å; L149-T153 PolarHBondContact O-N 3.17Å; L149-T153 PolarHBondContact O-OG1 2.96Å; L149-T153 VanDerWaalsContact O-OG1 3.1Å; L149-T318 HydrophobicContact CD2-CG2 3.87Å; L149-A322 HydrophobicContact CD1-CB 4.43Å
150	V	95	Very high	94.5	Very high	82 Å²	82	40.4 Å²	40.4	50%	0.497	22%	0.218	S	C	.	.	H	α-helix	trans	-59.8	-45.3	177	167.9	0	0	0	0	110.9	F25 S146 I147 T153 A154	F25-V150 HydrophobicContact CE2-CG1 4.5Å; S146-V150 WeakPolarHBondContact O-CB 3.26Å; S146-V150 VanDerWaalsContact O-CG2 3.29Å; S146-V150 WeakPolarHBondContact O-CG2 3.28Å; S146-V150 PolarHBondContact O-N 3.36Å; I147-V150 PolarHBondContact O-N 2.91Å; V150-T153 PolarHBondContact O-N 2.98Å; V150-A154 WeakPolarHBondContact O-CB 3.5Å; V150-A154 PolarHBondContact O-N 2.9Å
151	A	96.8	Very high	94.7	Very high	0 Å²	0	44.6 Å²	44.6	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-61.5	-45.6	178.6	0	0	0	0	0	112.1	F25 M28 F29 I147 T148 L149 A154 G155	F25-A151 HydrophobicContact CB-CB 4.43Å; F25-A151 HydrophobicContact CD2-CB 3.61Å; F25-A151 HydrophobicContact CE2-CB 3.96Å; F25-A151 HydrophobicContact CG-CB 4.04Å; F25-A151 VanDerWaalsContact O-CB 3.25Å; F25-A151 WeakPolarHBondContact O-CB 3.29Å; M28-A151 HydrophobicContact CB-CB 4.08Å; F29-A151 HydrophobicContact CB-CB 4.28Å; F29-A151 WeakPolarHBondContact CD2-O 3.12Å; I147-A151 VanDerWaalsContact O-CB 3.25Å; I147-A151 WeakPolarHBondContact O-CB 3.41Å; I147-A151 PolarHBondContact O-N 3.48Å; T148-A151 PolarHBondContact O-N 3.31Å; L149-A151 VanDerWaalsContact C-N 3.33Å; L149-A151 PolarHBondContact O-N 2.95Å; A151-A154 PolarHBondContact O-N 3.15Å; A151-G155 PolarHBondContact O-N 3.41Å
152	Y	95.1	Very high	94.9	Very high	42 Å²	42	45.8 Å²	45.8	17%	0.165	25%	0.245	C	C	.	.	H	α-helix	trans	-62.4	-49.9	177.9	-169.5	-99.6	0	0	0	111.2	M28 E33 T148 L149 A154 G155 S156 E314 T318	M28-Y152 HydrophobicContact CE-CD2 4.44Å; E33-Y152 HydrophobicContact CB-CE2 4.45Å; E33-Y152 HydrophobicContact CG-CE2 4.17Å; T148-Y152 WeakPolarHBondContact O-CB 3.48Å; T148-Y152 PolarHBondContact O-N 2.93Å; L149-Y152 PolarHBondContact O-N 3.33Å; Y152-A154 PolarHBondContact O-N 3.37Å; Y152-G155 PolarHBondContact O-N 2.83Å; Y152-S156 PolarHBondContact O-N 3.01Å; Y152-S156 PolarHBondContact O-OG 3Å; Y152-E314 HydrophobicContact CE1-CG 3.62Å; Y152-E314 WeakPolarHBondContact OH-CG 3.49Å; Y152-E314 PolarHBondContact OH-OE1 3.26Å; Y152-T318 HydrophobicContact CD1-CG2 4.03Å; Y152-T318 WeakPolarHBondContact CD1-OG1 3.41Å; Y152-T318 WeakPolarHBondContact CE1-OG1 3.35Å
153	T	95.5	Very high	94.9	Very high	37 Å²	37	44 Å²	44	23%	0.227	23%	0.232	C	C	.	.	H	α-helix	trans	-59.6	-45.5	176.5	-59.6	0	0	0	0	112.1	L149 V150 G155 S156 V157 A315 T318	L149-T153 WeakPolarHBondContact O-CB 3.44Å; L149-T153 PolarHBondContact O-N 3.17Å; L149-T153 PolarHBondContact O-OG1 2.96Å; L149-T153 VanDerWaalsContact O-OG1 3.1Å; V150-T153 PolarHBondContact O-N 2.98Å; T153-G155 VanDerWaalsContact C-N 3.33Å; T153-G155 PolarHBondContact O-N 3.19Å; T153-S156 PolarHBondContact O-N 2.99Å; T153-V157 HydrophobicContact CG2-CG2 4.44Å; T153-V157 WeakPolarHBondContact O-CG2 3.47Å; T153-V157 PolarHBondContact O-N 3.25Å; T153-A315 HydrophobicContact CG2-CB 4.16Å; T153-T318 WeakPolarHBondContact OG1-CG2 3.49Å
154	A	96.2	Very high	94.8	Very high	40 Å²	40	41.7 Å²	41.7	33%	0.331	23%	0.232	S	C	.	.	H	α-helix	trans	-63.7	-39.6	178.6	0	0	0	0	0	111.7	F29 V150 A151 Y152 V157 L158	F29-A154 HydrophobicContact CD2-CB 4.2Å; F29-A154 HydrophobicContact CE2-CB 3.72Å; V150-A154 WeakPolarHBondContact O-CB 3.5Å; V150-A154 PolarHBondContact O-N 2.9Å; A151-A154 PolarHBondContact O-N 3.15Å; Y152-A154 PolarHBondContact O-N 3.37Å; A154-V157 PolarHBondContact O-N 2.87Å; A154-L158 WeakPolarHBondContact O-CB 3.37Å; A154-L158 PolarHBondContact O-N 2.9Å
155	G	97.3	Very high	94.7	Very high	0 Å²	0	48 Å²	48	0%	0	27%	0.265	C	S	.	.	H	α-helix	trans	-60.2	-48.8	173	0	0	0	0	0	112	P31 A151 Y152 T153 V157 L158 A159	P31-G155 WeakPolarHBondContact CA-O 3.25Å; P31-G155 WeakPolarHBondContact CB-O 3.35Å; A151-G155 PolarHBondContact O-N 3.41Å; Y152-G155 PolarHBondContact O-N 2.83Å; T153-G155 VanDerWaalsContact C-N 3.33Å; T153-G155 PolarHBondContact O-N 3.19Å; G155-V157 PolarHBondContact O-N 2.69Å; G155-L158 PolarHBondContact O-N 3.47Å; G155-A159 WeakPolarHBondContact O-CB 3.29Å; G155-A159 PolarHBondContact O-N 3.32Å
156	S	96.5	Very high	94.4	Very high	1 Å²	1	45.4 Å²	45.4	1%	0.007	26%	0.263	C	S	.	.	H	α-helix	trans	-64.6	-39.2	178.8	-51.3	0	0	0	0	113	Y152 T153 A159 Q160 G311	Y152-S156 PolarHBondContact O-N 3.01Å; Y152-S156 PolarHBondContact O-OG 3Å; T153-S156 PolarHBondContact O-N 2.99Å; S156-A159 PolarHBondContact O-N 3.41Å; S156-Q160 PolarHBondContact O-N 3.39Å; S156-G311 VanDerWaalsContact CB-O 3.31Å; S156-G311 WeakPolarHBondContact CB-O 3.3Å; S156-G311 CarbonylContact O-C 3.56Å
157	V	96.2	Very high	93.8	Very high	65 Å²	65	49.2 Å²	49.2	39%	0.394	28%	0.278	S	S	.	.	H	α-helix	trans	-64.9	-47.7	174.5	170.7	0	0	0	0	110.7	T153 A154 G155 A159 Q160 L161 A315	T153-V157 HydrophobicContact CG2-CG2 4.44Å; T153-V157 WeakPolarHBondContact O-CG2 3.47Å; T153-V157 PolarHBondContact O-N 3.25Å; A154-V157 PolarHBondContact O-N 2.87Å; G155-V157 PolarHBondContact O-N 2.69Å; V157-A159 VanDerWaalsContact C-N 3.3Å; V157-A159 PolarHBondContact O-N 3.47Å; V157-Q160 PolarHBondContact O-N 2.66Å; V157-L161 HydrophobicContact CG1-CD1 3.95Å; V157-L161 HydrophobicContact CG1-CG 4.38Å; V157-L161 WeakPolarHBondContact O-CG 3.32Å; V157-L161 PolarHBondContact O-N 3.43Å; V157-A315 HydrophobicContact CG2-CB 3.75Å
158	L	96.2	Very high	93.3	Very high	58 Å²	58	50.2 Å²	50.2	30%	0.304	28%	0.284	S	S	.	.	H	α-helix	trans	-58.3	-45.7	176.8	177.7	63.9	0	0	0	110.7	F29 A154 G155 Q160 L161 L162	F29-L158 HydrophobicContact CE1-CD2 3.77Å; F29-L158 HydrophobicContact CZ-CB 4.29Å; F29-L158 HydrophobicContact CZ-CD2 3.6Å; A154-L158 WeakPolarHBondContact O-CB 3.37Å; A154-L158 PolarHBondContact O-N 2.9Å; G155-L158 PolarHBondContact O-N 3.47Å; L158-Q160 VanDerWaalsContact C-N 3.34Å; L158-Q160 PolarHBondContact O-N 2.95Å; L158-L161 PolarHBondContact O-N 3.43Å; L158-L162 HydrophobicContact CD1-CD1 4.02Å; L158-L162 HydrophobicContact CD1-CD2 4.41Å; L158-L162 HydrophobicContact CD1-CG 3.98Å; L158-L162 HydrophobicContact CD2-CD1 4.43Å; L158-L162 HydrophobicContact CG-CD1 3.88Å; L158-L162 HydrophobicContact CG-CG 4.25Å; L158-L162 VanDerWaalsContact O-CG 3.31Å; L158-L162 WeakPolarHBondContact O-CG 3.34Å; L158-L162 PolarHBondContact O-N 2.92Å
159	A	95.6	Very high	93.2	Very high	0 Å²	0	52.9 Å²	52.9	0%	0	30%	0.301	C	S	.	.	H	α-helix	trans	-56.8	-48.1	178.1	0	0	0	0	0	111.8	P31 F35 G155 S156 V157 L161 L162 V163 L173	P31-A159 HydrophobicContact CB-CB 3.68Å; P31-A159 WeakPolarHBondContact O-CB 3.4Å; F35-A159 HydrophobicContact CD2-CB 4.02Å; F35-A159 HydrophobicContact CE2-CB 3.65Å; G155-A159 WeakPolarHBondContact O-CB 3.29Å; G155-A159 PolarHBondContact O-N 3.32Å; S156-A159 PolarHBondContact O-N 3.41Å; V157-A159 VanDerWaalsContact C-N 3.3Å; V157-A159 PolarHBondContact O-N 3.47Å; A159-L161 PolarHBondContact O-N 3.44Å; A159-L162 PolarHBondContact O-N 3.39Å; A159-V163 WeakPolarHBondContact O-CG2 3.49Å; A159-V163 PolarHBondContact O-N 2.96Å; A159-L173 HydrophobicContact CB-CD1 4.41Å; A159-L173 HydrophobicContact CB-CD2 4.46Å
160	Q	95.6	Very high	93.2	Very high	15 Å²	15	50.7 Å²	50.7	7%	0.07	29%	0.288	C	S	.	.	H	α-helix	trans	-63	-42.4	178.4	-169.5	65.5	49.5	0	0	112.1	S156 V157 L158 S164 I308 Y309 A312	S156-Q160 PolarHBondContact O-N 3.39Å; V157-Q160 PolarHBondContact O-N 2.66Å; L158-Q160 VanDerWaalsContact C-N 3.34Å; L158-Q160 PolarHBondContact O-N 2.95Å; Q160-S164 PolarHBondContact NE2-OG 3.48Å; Q160-S164 VanDerWaalsContact O-CB 3.26Å; Q160-S164 WeakPolarHBondContact O-CB 3.15Å; Q160-S164 PolarHBondContact O-N 3.23Å; Q160-S164 PolarHBondContact O-OG 3.2Å; Q160-I308 PolarHBondContact NE2-O 2.94Å; Q160-I308 VanDerWaalsContact NE2-O 3.12Å; Q160-Y309 VanDerWaalsContact OE1-CA 3.24Å; Q160-Y309 PolarHBondContact OE1-O 3.18Å; Q160-A312 HydrophobicContact CB-CB 4.48Å; Q160-A312 HydrophobicContact CG-CB 3.88Å; Q160-A312 VanDerWaalsContact OE1-N 3.16Å
161	L	95.2	Very high	93.2	Very high	89 Å²	89	48.3 Å²	48.3	47%	0.466	27%	0.274	S	S	.	.	H	α-helix	trans	-62.6	-44.2	177.8	-70.1	173.2	0	0	0	111.5	V157 L158 A159 L165	V157-L161 HydrophobicContact CG1-CD1 3.95Å; V157-L161 HydrophobicContact CG1-CG 4.38Å; V157-L161 WeakPolarHBondContact O-CG 3.32Å; V157-L161 PolarHBondContact O-N 3.43Å; L158-L161 PolarHBondContact O-N 3.43Å; A159-L161 PolarHBondContact O-N 3.44Å; L161-L165 HydrophobicContact CB-CD1 4.38Å; L161-L165 HydrophobicContact CD2-CD1 4.01Å; L161-L165 WeakPolarHBondContact O-CB 3.49Å; L161-L165 VanDerWaalsContact O-CG 3.28Å; L161-L165 WeakPolarHBondContact O-CG 3.14Å; L161-L165 PolarHBondContact O-N 2.87Å
162	L	94.7	Very high	93.2	Very high	33 Å²	33	49.6 Å²	49.6	17%	0.173	28%	0.284	C	S	.	.	H	α-helix	trans	-63.8	-48.4	178.5	-68.7	176.2	0	0	0	111.4	L158 A159 S164 T166 L168 L173 I176	L158-L162 HydrophobicContact CD1-CD1 4.02Å; L158-L162 HydrophobicContact CD1-CD2 4.41Å; L158-L162 HydrophobicContact CD1-CG 3.98Å; L158-L162 HydrophobicContact CD2-CD1 4.43Å; L158-L162 HydrophobicContact CG-CD1 3.88Å; L158-L162 HydrophobicContact CG-CG 4.25Å; L158-L162 VanDerWaalsContact O-CG 3.31Å; L158-L162 WeakPolarHBondContact O-CG 3.34Å; L158-L162 PolarHBondContact O-N 2.92Å; A159-L162 PolarHBondContact O-N 3.39Å; L162-S164 PolarHBondContact O-N 3.5Å; L162-T166 PolarHBondContact O-N 3.36Å; L162-T166 PolarHBondContact O-OG1 3.28Å; L162-L168 HydrophobicContact CB-CD1 4.33Å; L162-L168 HydrophobicContact CD2-CD1 3.99Å; L162-L173 HydrophobicContact CB-CD2 4.14Å; L162-L173 HydrophobicContact CD1-CD2 3.89Å; L162-I176 HydrophobicContact CD1-CD1 3.64Å
163	V	91.9	Very high	93.3	Very high	22 Å²	22	47.7 Å²	47.7	13%	0.133	28%	0.276	C	S	.	.	H	α-helix	trans	-63	-44.7	179.5	172.2	0	0	0	0	111.3	F35 A159 Y170 L173	F35-V163 HydrophobicContact CD1-CG2 4.32Å; F35-V163 HydrophobicContact CD2-CG2 4.44Å; F35-V163 HydrophobicContact CE1-CB 4.31Å; F35-V163 HydrophobicContact CE1-CG1 4.06Å; F35-V163 HydrophobicContact CE1-CG2 3.97Å; F35-V163 HydrophobicContact CE2-CG2 4.1Å; F35-V163 HydrophobicContact CZ-CB 4.14Å; F35-V163 HydrophobicContact CZ-CG1 4.33Å; F35-V163 HydrophobicContact CZ-CG2 3.85Å; A159-V163 WeakPolarHBondContact O-CG2 3.49Å; A159-V163 PolarHBondContact O-N 2.96Å; V163-Y170 HydrophobicContact CG1-CE1 4.05Å; V163-Y170 HydrophobicContact CG2-CD1 4.14Å; V163-Y170 HydrophobicContact CG2-CE1 3.96Å; V163-L173 HydrophobicContact CG2-CD1 3.79Å
164	S	90.8	Very high	93.3	Very high	60 Å²	60	45.9 Å²	45.9	42%	0.42	27%	0.265	S	S	.	.	H	α-helix	trans	-79.4	-28.9	-175.6	-63.6	0	0	0	0	114.8	Q160 L162	Q160-S164 PolarHBondContact NE2-OG 3.48Å; Q160-S164 VanDerWaalsContact O-CB 3.26Å; Q160-S164 WeakPolarHBondContact O-CB 3.15Å; Q160-S164 PolarHBondContact O-N 3.23Å; Q160-S164 PolarHBondContact O-OG 3.2Å; L162-S164 PolarHBondContact O-N 3.5Å
165	L	91	Very high	93.4	Very high	132 Å²	132	49.3 Å²	49.3	69%	0.691	27%	0.27	S	S	*	.	H	α-helix	trans	-103.4	-27.9	-173.9	-58.8	177.3	0	0	0	114	L161	L161-L165 HydrophobicContact CB-CD1 4.38Å; L161-L165 HydrophobicContact CD2-CD1 4.01Å; L161-L165 WeakPolarHBondContact O-CB 3.49Å; L161-L165 VanDerWaalsContact O-CG 3.28Å; L161-L165 WeakPolarHBondContact O-CG 3.14Å; L161-L165 PolarHBondContact O-N 2.87Å
166	T	84.9	Confident	93.4	Very high	73 Å²	73	51.8 Å²	51.8	45%	0.448	28%	0.283	S	S	.	.	H	α-helix	trans	-116.3	-1.4	-167.6	62.9	0	0	0	0	114.6	L162 L168	L162-T166 PolarHBondContact O-N 3.36Å; L162-T166 PolarHBondContact O-OG1 3.28Å; T166-L168 PolarHBondContact O-N 2.88Å; T166-L168 VanDerWaalsContact OG1-CD1 3.24Å; T166-L168 WeakPolarHBondContact OG1-CD1 3.43Å; T166-L168 WeakPolarHBondContact OG1-CG 3.33Å
167	N	81	Confident	93.4	Very high	150 Å²	150	51.8 Å²	51.8	80%	0.802	28%	0.283	S	S	*	.			trans	46.9	28.4	-174.6	-67.3	-26.7	0	0	0	112.8
168	L	87.1	Confident	93.4	Very high	67 Å²	67	50 Å²	50	35%	0.351	27%	0.271	S	S	.	.			trans	-65.7	139	179.8	-79.9	172.9	0	0	0	109.4	L162 T166	L162-L168 HydrophobicContact CB-CD1 4.33Å; L162-L168 HydrophobicContact CD2-CD1 3.99Å; T166-L168 PolarHBondContact O-N 2.88Å; T166-L168 VanDerWaalsContact OG1-CD1 3.24Å; T166-L168 WeakPolarHBondContact OG1-CD1 3.43Å; T166-L168 WeakPolarHBondContact OG1-CG 3.33Å
169	P	91.8	Very high	93.5	Very high	67 Å²	67	49.9 Å²	49.9	44%	0.435	28%	0.278	S	S	.	.			trans	-63.7	148.3	175.5	27.9	-33.8	0	0	0	109.8	S171 S172	P169-S171 PolarHBondContact O-N 3.2Å; P169-S171 VanDerWaalsContact O-N 3.12Å; P169-S172 VanDerWaalsContact O-CB 3.28Å; P169-S172 WeakPolarHBondContact O-CB 3.47Å; P169-S172 PolarHBondContact O-N 3.43Å; P169-S172 PolarHBondContact O-OG 3.21Å
170	Y	94	Very high	93.6	Very high	32 Å²	32	50.6 Å²	50.6	13%	0.125	28%	0.283	C	S	.	.	H	α-helix	trans	-58.9	-31.3	-175.5	-63.5	-56.6	0	0	0	112.3	F35 P38 E42 V163 S172 L173 F174 I308	F35-Y170 HydrophobicContact CB-CD1 3.98Å; F35-Y170 HydrophobicContact CB-CE1 4.37Å; F35-Y170 AromaticContact CD1-CD1 3.96Å; F35-Y170 HydrophobicContact CD1-CD1 3.96Å; F35-Y170 AromaticContact CD1-CE1 3.52Å; F35-Y170 HydrophobicContact CD1-CE1 3.52Å; F35-Y170 HydrophobicContact CE1-CE1 4.11Å; F35-Y170 HydrophobicContact CG-CD1 4.14Å; F35-Y170 HydrophobicContact CG-CE1 4.17Å; P38-Y170 HydrophobicContact CB-CD2 4.13Å; P38-Y170 HydrophobicContact CB-CE1 4.32Å; P38-Y170 HydrophobicContact CB-CE2 3.7Å; E42-Y170 HydrophobicContact CG-CD2 4.08Å; E42-Y170 WeakPolarHBondContact OE1-CD2 3.31Å; V163-Y170 HydrophobicContact CG1-CE1 4.05Å; V163-Y170 HydrophobicContact CG2-CD1 4.14Å; V163-Y170 HydrophobicContact CG2-CE1 3.96Å; Y170-S172 PolarHBondContact O-N 3.32Å; Y170-S172 VanDerWaalsContact O-N 3.11Å; Y170-L173 HydrophobicContact CD1-CD1 4.29Å; Y170-L173 VanDerWaalsContact O-CB 3.3Å; Y170-L173 WeakPolarHBondContact O-CB 3.28Å; Y170-L173 PolarHBondContact O-N 2.94Å; Y170-F174 WeakPolarHBondContact O-CD2 3.24Å; Y170-I308 WeakPolarHBondContact OH-CD1 3.38Å
171	S	94.9	Very high	93.6	Very high	31 Å²	31	50 Å²	50	22%	0.217	28%	0.281	C	S	.	.	H	α-helix	trans	-51.6	-32.5	173.1	59.4	0	0	0	0	113.8	P169 L173 F174 Y175	P169-S171 PolarHBondContact O-N 3.2Å; P169-S171 VanDerWaalsContact O-N 3.12Å; S171-L173 VanDerWaalsContact C-N 3.29Å; S171-L173 PolarHBondContact O-N 3.11Å; S171-F174 WeakPolarHBondContact O-CB 3.44Å; S171-F174 PolarHBondContact O-N 3.39Å; S171-Y175 WeakPolarHBondContact O-CD2 3.47Å; S171-Y175 PolarHBondContact O-N 3.45Å
172	S	96	Very high	93.6	Very high	28 Å²	28	48.9 Å²	48.9	20%	0.196	28%	0.28	C	S	.	.	H	α-helix	trans	-61.2	-37.9	175.6	-54.8	0	0	0	0	112	P169 Y170 F174 Y175 I176	P169-S172 VanDerWaalsContact O-CB 3.28Å; P169-S172 WeakPolarHBondContact O-CB 3.47Å; P169-S172 PolarHBondContact O-N 3.43Å; P169-S172 PolarHBondContact O-OG 3.21Å; Y170-S172 PolarHBondContact O-N 3.32Å; Y170-S172 VanDerWaalsContact O-N 3.11Å; S172-F174 VanDerWaalsContact C-N 3.32Å; S172-F174 PolarHBondContact O-N 3.26Å; S172-Y175 PolarHBondContact O-N 2.94Å; S172-I176 VanDerWaalsContact O-CG1 3.3Å; S172-I176 WeakPolarHBondContact O-CG1 3.44Å; S172-I176 PolarHBondContact O-N 3.44Å
173	L	96.6	Very high	93.7	Very high	1 Å²	1	50 Å²	50	1%	0.005	29%	0.288	C	S	.	.	H	α-helix	trans	-65.2	-38.7	177.3	-54.4	179.1	0	0	0	111.3	P31 F35 A159 L162 V163 Y170 S171 I176 S177	P31-L173 HydrophobicContact CB-CD2 4.45Å; F35-L173 HydrophobicContact CB-CD1 4.04Å; F35-L173 HydrophobicContact CD2-CD1 3.6Å; F35-L173 HydrophobicContact CE2-CD1 4.29Å; F35-L173 HydrophobicContact CG-CD1 3.92Å; A159-L173 HydrophobicContact CB-CD1 4.41Å; A159-L173 HydrophobicContact CB-CD2 4.46Å; L162-L173 HydrophobicContact CB-CD2 4.14Å; L162-L173 HydrophobicContact CD1-CD2 3.89Å; V163-L173 HydrophobicContact CG2-CD1 3.79Å; Y170-L173 HydrophobicContact CD1-CD1 4.29Å; Y170-L173 VanDerWaalsContact O-CB 3.3Å; Y170-L173 WeakPolarHBondContact O-CB 3.28Å; Y170-L173 PolarHBondContact O-N 2.94Å; S171-L173 VanDerWaalsContact C-N 3.29Å; S171-L173 PolarHBondContact O-N 3.11Å; L173-I176 PolarHBondContact O-N 2.9Å; L173-S177 PolarHBondContact O-N 2.89Å; L173-S177 PolarHBondContact O-OG 3.15Å
174	F	97	Very high	94	Very high	0 Å²	0	49 Å²	49	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-66.5	-39.8	176	-76.6	-94.9	0	0	0	112.1	L36 F39 Y95 L98 L99 Y170 S171 S172 S177 L178	L36-F174 HydrophobicContact CD1-CE1 4.07Å; L36-F174 HydrophobicContact CD1-CZ 3.85Å; F39-F174 HydrophobicContact CB-CD2 4.4Å; F39-F174 HydrophobicContact CB-CE2 3.47Å; F39-F174 VanDerWaalsContact CB-CE2 3.47Å; F39-F174 HydrophobicContact CB-CZ 3.97Å; F39-F174 HydrophobicContact CD1-CD2 4.13Å; F39-F174 HydrophobicContact CD1-CE1 4.16Å; F39-F174 AromaticContact CD1-CE2 3.51Å; F39-F174 HydrophobicContact CD1-CE2 3.51Å; F39-F174 AromaticContact CD1-CZ 3.51Å; F39-F174 HydrophobicContact CD1-CZ 3.51Å; F39-F174 HydrophobicContact CD2-CD2 4.07Å; F39-F174 AromaticContact CD2-CE2 3.93Å; F39-F174 HydrophobicContact CD2-CE2 3.93Å; F39-F174 HydrophobicContact CE1-CD2 4.42Å; F39-F174 HydrophobicContact CE1-CE1 4.41Å; F39-F174 HydrophobicContact CE1-CE2 4.2Å; F39-F174 HydrophobicContact CE1-CZ 4.16Å; F39-F174 HydrophobicContact CE2-CD2 4.37Å; F39-F174 AromaticContact CG-CD2 3.93Å; F39-F174 HydrophobicContact CG-CD2 3.93Å; F39-F174 AromaticContact CG-CE2 3.34Å; F39-F174 HydrophobicContact CG-CE2 3.34Å; F39-F174 AromaticContact CG-CZ 3.83Å; F39-F174 HydrophobicContact CG-CZ 3.83Å; Y95-F174 AromaticContact CD1-CD1 3.87Å; Y95-F174 HydrophobicContact CD1-CD1 3.87Å; Y95-F174 AromaticContact CE1-CD1 3.75Å; Y95-F174 HydrophobicContact CE1-CD1 3.75Å; Y95-F174 HydrophobicContact CE1-CE1 4.27Å; L98-F174 HydrophobicContact CB-CD1 4.34Å; L98-F174 HydrophobicContact CB-CE1 4.24Å; L98-F174 HydrophobicContact CD1-CD1 4.4Å; L98-F174 HydrophobicContact CD1-CE1 3.83Å; L99-F174 HydrophobicContact CD1-CB 4.26Å; L99-F174 HydrophobicContact CD2-CB 3.49Å; L99-F174 VanDerWaalsContact CD2-CB 3.49Å; L99-F174 HydrophobicContact CD2-CG 4.37Å; L99-F174 HydrophobicContact CG-CB 3.88Å; Y170-F174 WeakPolarHBondContact O-CD2 3.24Å; S171-F174 WeakPolarHBondContact O-CB 3.44Å; S171-F174 PolarHBondContact O-N 3.39Å; S172-F174 VanDerWaalsContact C-N 3.32Å; S172-F174 PolarHBondContact O-N 3.26Å; F174-S177 PolarHBondContact O-N 3.36Å; F174-L178 WeakPolarHBondContact O-CB 3.43Å; F174-L178 PolarHBondContact O-N 3.44Å
175	Y	97.4	Very high	94.2	Very high	111 Å²	111	50 Å²	50	44%	0.435	28%	0.279	S	S	.	.	H	α-helix	trans	-62.9	-40.6	172.8	-70.4	-58.6	0	0	0	112.3	L99 F100 S171 S172 L178 A179	L99-Y175 HydrophobicContact CD1-CD1 3.78Å; L99-Y175 HydrophobicContact CD1-CE1 3.75Å; L99-Y175 HydrophobicContact CD2-CD1 4.26Å; L99-Y175 HydrophobicContact CD2-CD2 4.38Å; L99-Y175 HydrophobicContact CD2-CE1 3.99Å; L99-Y175 HydrophobicContact CD2-CE2 4.11Å; L99-Y175 HydrophobicContact CD2-CG 4.44Å; L99-Y175 HydrophobicContact CG-CE1 4.41Å; F100-Y175 HydrophobicContact CZ-CE1 4.08Å; S171-Y175 WeakPolarHBondContact O-CD2 3.47Å; S171-Y175 PolarHBondContact O-N 3.45Å; S172-Y175 PolarHBondContact O-N 2.94Å; Y175-L178 PolarHBondContact O-N 2.84Å; Y175-A179 WeakPolarHBondContact O-CB 3.46Å; Y175-A179 PolarHBondContact O-N 3.24Å
176	I	96.9	Very high	94.4	Very high	53 Å²	53	49 Å²	49	27%	0.272	27%	0.269	S	S	.	.	H	α-helix	trans	-62.7	-49	175.6	-65.4	164.3	0	0	0	110.4	P31 L162 S172 L173 L178 A179 C180	P31-I176 HydrophobicContact CG-CB 4.04Å; P31-I176 HydrophobicContact CG-CG2 3.66Å; L162-I176 HydrophobicContact CD1-CD1 3.64Å; S172-I176 VanDerWaalsContact O-CG1 3.3Å; S172-I176 WeakPolarHBondContact O-CG1 3.44Å; S172-I176 PolarHBondContact O-N 3.44Å; L173-I176 PolarHBondContact O-N 2.9Å; I176-L178 VanDerWaalsContact C-N 3.32Å; I176-L178 PolarHBondContact O-N 2.81Å; I176-A179 WeakPolarHBondContact O-CB 3.42Å; I176-A179 PolarHBondContact O-N 2.67Å; I176-C180 PolarHBondContact O-N 3.26Å; I176-C180 PolarHBondContact O-SG 3.49Å; I176-C180 VanDerWaalsContact O-SG 3.4Å
177	S	97.2	Very high	94.9	Very high	0 Å²	0	47.2 Å²	47.2	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-58.3	-43.1	176.2	-65.5	0	0	0	0	112.1	P31 S32 Y95 L173 F174 A179 C180 V181	P31-S177 VanDerWaalsContact CD-OG 3.25Å; P31-S177 WeakPolarHBondContact CD-OG 3.23Å; S32-S177 WeakPolarHBondContact CB-OG 3.21Å; S32-S177 PolarHBondContact N-OG 2.85Å; S32-S177 WeakPolarHBondContact OG-CB 3.35Å; S32-S177 PolarHBondContact OG-OG 3.41Å; Y95-S177 VanDerWaalsContact CE1-CB 3.45Å; L173-S177 PolarHBondContact O-N 2.89Å; L173-S177 PolarHBondContact O-OG 3.15Å; F174-S177 PolarHBondContact O-N 3.36Å; S177-A179 VanDerWaalsContact C-N 3.33Å; S177-A179 PolarHBondContact O-N 2.9Å; S177-C180 WeakPolarHBondContact O-CB 3.33Å; S177-C180 PolarHBondContact O-N 3.23Å; S177-V181 WeakPolarHBondContact O-CB 3.44Å; S177-V181 WeakPolarHBondContact O-CG2 3.47Å; S177-V181 PolarHBondContact O-N 3.25Å
178	L	96.6	Very high	95.5	Very high	27 Å²	27	40.1 Å²	40.1	14%	0.141	22%	0.217	C	C	.	.	H	α-helix	trans	-64	-37.6	177.4	-175.5	62.9	0	0	0	112	A92 L96 L99 F174 Y175 I176 V181 S182	A92-L178 HydrophobicContact CB-CD1 4.02Å; L96-L178 HydrophobicContact CD2-CD2 3.99Å; L99-L178 HydrophobicContact CD1-CD2 4.01Å; F174-L178 WeakPolarHBondContact O-CB 3.43Å; F174-L178 PolarHBondContact O-N 3.44Å; Y175-L178 PolarHBondContact O-N 2.84Å; I176-L178 VanDerWaalsContact C-N 3.32Å; I176-L178 PolarHBondContact O-N 2.81Å; L178-V181 PolarHBondContact O-N 3.43Å; L178-S182 WeakPolarHBondContact O-CB 3.49Å; L178-S182 PolarHBondContact O-N 3.4Å; L178-S182 PolarHBondContact O-OG 3.41Å
179	A	97.4	Very high	95.8	Very high	56 Å²	56	40.8 Å²	40.8	46%	0.463	22%	0.221	S	C	.	.	H	α-helix	trans	-63.8	-44.5	173.3	0	0	0	0	0	111.3	Y175 I176 S177 V181 S182 V183	Y175-A179 WeakPolarHBondContact O-CB 3.46Å; Y175-A179 PolarHBondContact O-N 3.24Å; I176-A179 WeakPolarHBondContact O-CB 3.42Å; I176-A179 PolarHBondContact O-N 2.67Å; S177-A179 VanDerWaalsContact C-N 3.33Å; S177-A179 PolarHBondContact O-N 2.9Å; A179-V181 PolarHBondContact O-N 2.9Å; A179-S182 WeakPolarHBondContact O-CB 3.46Å; A179-S182 PolarHBondContact O-N 3.27Å; A179-V183 WeakPolarHBondContact O-CG2 3.35Å; A179-V183 PolarHBondContact O-N 3.25Å
180	C	97.6	Very high	95.9	Very high	16 Å²	16	42.1 Å²	42.1	11%	0.108	22%	0.22	C	C	.	.	H	α-helix	trans	-60.4	-44.8	175.1	-68.1	0	0	0	0	111.9	F26 F29 I176 S177 S182 V183 A184	F26-C180 CarbonylContact O-C 3.46Å; F26-C180 WeakPolarHBondContact O-CB 3.41Å; F29-C180 VanDerWaalsContact CD1-SG 3.56Å; I176-C180 PolarHBondContact O-N 3.26Å; I176-C180 PolarHBondContact O-SG 3.49Å; I176-C180 VanDerWaalsContact O-SG 3.4Å; S177-C180 WeakPolarHBondContact O-CB 3.33Å; S177-C180 PolarHBondContact O-N 3.23Å; C180-S182 VanDerWaalsContact C-N 3.28Å; C180-S182 PolarHBondContact O-N 3.04Å; C180-V183 WeakPolarHBondContact O-CB 3.22Å; C180-V183 PolarHBondContact O-N 3.31Å; C180-V183 VanDerWaalsContact O-N 3.1Å; C180-A184 PolarHBondContact O-N 3.3Å
181	V	95.7	Very high	95.7	Very high	3 Å²	3	40.7 Å²	40.7	2%	0.018	21%	0.214	C	C	.	.	H	α-helix	trans	-61.5	-37.4	176	171.5	0	0	0	0	111.3	V88 F91 A92 S177 L178 A179 A184 F185	V88-V181 HydrophobicContact CG1-CG1 3.62Å; V88-V181 VanDerWaalsContact CG1-O 3.22Å; V88-V181 WeakPolarHBondContact CG1-O 3.36Å; F91-V181 HydrophobicContact CB-CG1 3.98Å; F91-V181 HydrophobicContact CD1-CB 4.13Å; F91-V181 HydrophobicContact CD1-CG1 3.8Å; F91-V181 HydrophobicContact CD1-CG2 3.29Å; F91-V181 HydrophobicContact CE1-CG2 3.44Å; F91-V181 VanDerWaalsContact CE1-CG2 3.44Å; F91-V181 HydrophobicContact CG-CG1 4.12Å; F91-V181 HydrophobicContact CG-CG2 3.98Å; F91-V181 HydrophobicContact CZ-CG2 4.3Å; A92-V181 HydrophobicContact CB-CG1 4.27Å; S177-V181 WeakPolarHBondContact O-CB 3.44Å; S177-V181 WeakPolarHBondContact O-CG2 3.47Å; S177-V181 PolarHBondContact O-N 3.25Å; L178-V181 PolarHBondContact O-N 3.43Å; A179-V181 PolarHBondContact O-N 2.9Å; V181-A184 WeakPolarHBondContact O-CB 3.47Å; V181-A184 PolarHBondContact O-N 3.48Å; V181-F185 PolarHBondContact O-N 3.38Å
182	S	95.3	Very high	95.4	Very high	65 Å²	65	40.9 Å²	40.9	46%	0.455	22%	0.215	S	C	.	.	H	α-helix	trans	-65.6	-37.5	174.8	-57.3	0	0	0	0	112.2	L178 A179 C180 F185 F186	L178-S182 WeakPolarHBondContact O-CB 3.49Å; L178-S182 PolarHBondContact O-N 3.4Å; L178-S182 PolarHBondContact O-OG 3.41Å; A179-S182 WeakPolarHBondContact O-CB 3.46Å; A179-S182 PolarHBondContact O-N 3.27Å; C180-S182 VanDerWaalsContact C-N 3.28Å; C180-S182 PolarHBondContact O-N 3.04Å; S182-F185 WeakPolarHBondContact O-CB 3.27Å; S182-F185 PolarHBondContact O-N 2.91Å; S182-F186 PolarHBondContact O-N 3.1Å; S182-F186 VanDerWaalsContact O-N 3.16Å
183	V	97.1	Very high	94.9	Very high	56 Å²	56	44.2 Å²	44.2	34%	0.339	23%	0.229	S	C	.	.	H	α-helix	trans	-67.8	-38.4	172	177.1	0	0	0	0	111	F26 A179 C180 F185 F186 F187	F26-V183 HydrophobicContact CB-CB 4.45Å; F26-V183 HydrophobicContact CB-CG1 4.35Å; F26-V183 HydrophobicContact CD1-CB 4.08Å; F26-V183 HydrophobicContact CD1-CG1 3.81Å; F26-V183 HydrophobicContact CD2-CG1 3.61Å; F26-V183 HydrophobicContact CE1-CB 4.5Å; F26-V183 HydrophobicContact CE1-CG1 3.95Å; F26-V183 HydrophobicContact CE2-CG1 3.77Å; F26-V183 HydrophobicContact CG-CB 4.11Å; F26-V183 HydrophobicContact CG-CG1 3.66Å; F26-V183 HydrophobicContact CZ-CG1 3.93Å; A179-V183 WeakPolarHBondContact O-CG2 3.35Å; A179-V183 PolarHBondContact O-N 3.25Å; C180-V183 WeakPolarHBondContact O-CB 3.22Å; C180-V183 PolarHBondContact O-N 3.31Å; C180-V183 VanDerWaalsContact O-N 3.1Å; V183-F185 VanDerWaalsContact C-N 3.31Å; V183-F185 PolarHBondContact O-N 3.43Å; V183-F186 WeakPolarHBondContact O-CB 3.43Å; V183-F186 PolarHBondContact O-N 3.42Å; V183-F187 HydrophobicContact CG1-CD2 3.93Å; V183-F187 HydrophobicContact CG1-CE2 3.62Å; V183-F187 VanDerWaalsContact O-CD2 3.27Å; V183-F187 WeakPolarHBondContact O-CD2 3.26Å; V183-F187 PolarHBondContact O-N 3.49Å; V183-F187 VanDerWaalsContact O-N 3.12Å
184	A	96.8	Very high	93.7	Very high	0 Å²	0	44.2 Å²	44.2	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-62	-39.4	173.2	0	0	0	0	0	111.7	F23 F26 V88 C180 V181 F186 F187 S188	F23-A184 HydrophobicContact CD2-CB 4.28Å; F23-A184 WeakPolarHBondContact CD2-O 2.88Å; F23-A184 HydrophobicContact CE2-CB 4.44Å; F26-A184 HydrophobicContact CB-CB 3.88Å; V88-A184 HydrophobicContact CG2-CB 4.45Å; C180-A184 PolarHBondContact O-N 3.3Å; V181-A184 WeakPolarHBondContact O-CB 3.47Å; V181-A184 PolarHBondContact O-N 3.48Å; A184-F186 VanDerWaalsContact C-N 3.32Å; A184-F186 PolarHBondContact O-N 2.79Å; A184-F187 PolarHBondContact O-N 2.96Å; A184-S188 PolarHBondContact O-N 3.5Å
185	F	95.2	Very high	92.2	Very high	81 Å²	81	53 Å²	53	36%	0.355	27%	0.267	S	S	.	.	H	α-helix	trans	-57.1	-47.6	173.9	-176	-106.8	0	0	0	110.8	V88 V89 V181 S182 V183 F187 S188 L189	V88-F185 HydrophobicContact CB-CB 4.48Å; V88-F185 HydrophobicContact CB-CD2 4.31Å; V88-F185 HydrophobicContact CG1-CB 3.57Å; V88-F185 HydrophobicContact CG1-CD2 4.12Å; V88-F185 HydrophobicContact CG1-CG 4.33Å; V89-F185 HydrophobicContact CG2-CD2 4.48Å; V89-F185 HydrophobicContact CG2-CE2 4.07Å; V181-F185 PolarHBondContact O-N 3.38Å; S182-F185 WeakPolarHBondContact O-CB 3.27Å; S182-F185 PolarHBondContact O-N 2.91Å; V183-F185 VanDerWaalsContact C-N 3.31Å; V183-F185 PolarHBondContact O-N 3.43Å; F185-F187 PolarHBondContact O-N 2.9Å; F185-S188 WeakPolarHBondContact O-CB 3.47Å; F185-S188 PolarHBondContact O-N 3.17Å; F185-S188 VanDerWaalsContact O-N 3.12Å; F185-S188 PolarHBondContact O-OG 3.38Å; F185-L189 HydrophobicContact CE1-CD1 4.26Å; F185-L189 HydrophobicContact CE1-CD2 4.38Å; F185-L189 HydrophobicContact CZ-CD2 4.28Å; F185-L189 PolarHBondContact O-N 2.89Å
186	F	95.7	Very high	90.5	Very high	112 Å²	112	53.8 Å²	53.8	49%	0.491	27%	0.273	S	S	.	.	H	α-helix	trans	-55.1	-49.8	176.4	175.1	-95.1	0	0	0	111.6	S182 V183 A184 S188 L189 F190	S182-F186 PolarHBondContact O-N 3.1Å; S182-F186 VanDerWaalsContact O-N 3.16Å; V183-F186 WeakPolarHBondContact O-CB 3.43Å; V183-F186 PolarHBondContact O-N 3.42Å; A184-F186 VanDerWaalsContact C-N 3.32Å; A184-F186 PolarHBondContact O-N 2.79Å; F186-S188 VanDerWaalsContact C-N 3.3Å; F186-S188 PolarHBondContact O-N 3.29Å; F186-L189 WeakPolarHBondContact O-CB 3.22Å; F186-L189 PolarHBondContact O-N 2.89Å; F186-F190 HydrophobicContact CD1-CD2 4.38Å; F186-F190 HydrophobicContact CD1-CE2 4.02Å; F186-F190 AromaticContact CD2-CE2 3.92Å; F186-F190 HydrophobicContact CD2-CE2 3.92Å; F186-F190 HydrophobicContact CE1-CD2 4.13Å; F186-F190 AromaticContact CE1-CE2 3.58Å; F186-F190 HydrophobicContact CE1-CE2 3.58Å; F186-F190 HydrophobicContact CE1-CZ 4.39Å; F186-F190 AromaticContact CE2-CE2 3.5Å; F186-F190 HydrophobicContact CE2-CE2 3.5Å; F186-F190 VanDerWaalsContact CE2-CE2 3.5Å; F186-F190 AromaticContact CE2-CZ 3.93Å; F186-F190 HydrophobicContact CE2-CZ 3.93Å; F186-F190 HydrophobicContact CG-CE2 4.17Å; F186-F190 HydrophobicContact CZ-CD2 4.28Å; F186-F190 AromaticContact CZ-CE2 3.31Å; F186-F190 HydrophobicContact CZ-CE2 3.31Å; F186-F190 AromaticContact CZ-CZ 3.75Å; F186-F190 HydrophobicContact CZ-CZ 3.75Å; F186-F190 WeakPolarHBondContact O-CD2 3.25Å
187	F	96.2	Very high	88.7	Confident	36 Å²	36	51.6 Å²	51.6	16%	0.158	26%	0.262	C	S	.	.	H	α-helix	trans	-64.4	-32.3	177.7	-75.2	-66	0	0	0	113.6	I19 L22 F23 F26 V183 A184 F185 L189 F190 L191	I19-F187 HydrophobicContact CD1-CD1 4.4Å; I19-F187 HydrophobicContact CG2-CB 4.45Å; I19-F187 WeakPolarHBondContact CG2-O 3.39Å; L22-F187 HydrophobicContact CB-CD1 3.98Å; L22-F187 HydrophobicContact CB-CD2 4.09Å; L22-F187 HydrophobicContact CB-CE1 4.05Å; L22-F187 HydrophobicContact CB-CE2 4.15Å; L22-F187 HydrophobicContact CB-CG 4.01Å; L22-F187 HydrophobicContact CB-CZ 4.13Å; L22-F187 HydrophobicContact CD1-CD1 4.09Å; L22-F187 HydrophobicContact CD1-CE1 3.55Å; L22-F187 HydrophobicContact CD1-CZ 3.91Å; L22-F187 HydrophobicContact CD2-CZ 4.48Å; L22-F187 HydrophobicContact CG-CE1 4.35Å; L22-F187 HydrophobicContact CG-CZ 4.4Å; F23-F187 HydrophobicContact CB-CB 4.23Å; F26-F187 AromaticContact CD2-CD2 3.87Å; F26-F187 HydrophobicContact CD2-CD2 3.87Å; F26-F187 AromaticContact CD2-CE2 3.65Å; F26-F187 HydrophobicContact CD2-CE2 3.65Å; F26-F187 HydrophobicContact CE2-CD2 4.28Å; F26-F187 AromaticContact CE2-CE2 3.58Å; F26-F187 HydrophobicContact CE2-CE2 3.58Å; F26-F187 HydrophobicContact CE2-CZ 4.42Å; V183-F187 HydrophobicContact CG1-CD2 3.93Å; V183-F187 HydrophobicContact CG1-CE2 3.62Å; V183-F187 VanDerWaalsContact O-CD2 3.27Å; V183-F187 WeakPolarHBondContact O-CD2 3.26Å; V183-F187 PolarHBondContact O-N 3.49Å; V183-F187 VanDerWaalsContact O-N 3.12Å; A184-F187 PolarHBondContact O-N 2.96Å; F185-F187 PolarHBondContact O-N 2.9Å; F187-L189 PolarHBondContact O-N 2.99Å; F187-F190 PolarHBondContact O-N 3.43Å; F187-F190 VanDerWaalsContact O-N 3.12Å; F187-L191 PolarHBondContact O-N 3.01Å
188	S	94	Very high	86.6	Confident	0 Å²	0	55.5 Å²	55.5	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-61	-28.9	176.4	82.7	0	0	0	0	113	K81 M85 A184 F185 F186 F190 L191	K81-S188 VanDerWaalsContact CE-O 3.3Å; K81-S188 WeakPolarHBondContact CE-O 3.21Å; M85-S188 WeakPolarHBondContact CE-O 3.23Å; A184-S188 PolarHBondContact O-N 3.5Å; F185-S188 WeakPolarHBondContact O-CB 3.47Å; F185-S188 PolarHBondContact O-N 3.17Å; F185-S188 VanDerWaalsContact O-N 3.12Å; F185-S188 PolarHBondContact O-OG 3.38Å; F186-S188 VanDerWaalsContact C-N 3.3Å; F186-S188 PolarHBondContact O-N 3.29Å; S188-F190 VanDerWaalsContact C-N 3.33Å; S188-F190 PolarHBondContact O-N 3.19Å; S188-L191 PolarHBondContact O-N 3.27Å
189	L	93.5	Very high	84.5	Confident	81 Å²	81	58.9 Å²	58.9	42%	0.424	30%	0.295	S	S	.	.	H	α-helix	trans	-66.1	-35.9	177	-60.9	170	0	0	0	111.9	K81 M85 F185 F186 F187	K81-L189 PolarHBondContact NZ-O 2.89Å; M85-L189 HydrophobicContact CE-CD2 3.8Å; F185-L189 HydrophobicContact CE1-CD1 4.26Å; F185-L189 HydrophobicContact CE1-CD2 4.38Å; F185-L189 HydrophobicContact CZ-CD2 4.28Å; F185-L189 PolarHBondContact O-N 2.89Å; F186-L189 WeakPolarHBondContact O-CB 3.22Å; F186-L189 PolarHBondContact O-N 2.89Å; F187-L189 PolarHBondContact O-N 2.99Å
190	F	93.2	Very high	82.1	Confident	96 Å²	96	62.9 Å²	62.9	42%	0.421	30%	0.302	S	S	.	.	H	α-helix	trans	-86.6	-4.2	-177.5	-62.6	-82.3	0	0	0	114	Y15 I19 F186 F187 S188	Y15-F190 PolarHBondContact OH-O 2.95Å; I19-F190 HydrophobicContact CG2-CB 4.24Å; F186-F190 HydrophobicContact CD1-CD2 4.38Å; F186-F190 HydrophobicContact CD1-CE2 4.02Å; F186-F190 AromaticContact CD2-CE2 3.92Å; F186-F190 HydrophobicContact CD2-CE2 3.92Å; F186-F190 HydrophobicContact CE1-CD2 4.13Å; F186-F190 AromaticContact CE1-CE2 3.58Å; F186-F190 HydrophobicContact CE1-CE2 3.58Å; F186-F190 HydrophobicContact CE1-CZ 4.39Å; F186-F190 AromaticContact CE2-CE2 3.5Å; F186-F190 HydrophobicContact CE2-CE2 3.5Å; F186-F190 VanDerWaalsContact CE2-CE2 3.5Å; F186-F190 AromaticContact CE2-CZ 3.93Å; F186-F190 HydrophobicContact CE2-CZ 3.93Å; F186-F190 HydrophobicContact CG-CE2 4.17Å; F186-F190 HydrophobicContact CZ-CD2 4.28Å; F186-F190 AromaticContact CZ-CE2 3.31Å; F186-F190 HydrophobicContact CZ-CE2 3.31Å; F186-F190 AromaticContact CZ-CZ 3.75Å; F186-F190 HydrophobicContact CZ-CZ 3.75Å; F186-F190 WeakPolarHBondContact O-CD2 3.25Å; F187-F190 PolarHBondContact O-N 3.43Å; F187-F190 VanDerWaalsContact O-N 3.12Å; S188-F190 VanDerWaalsContact C-N 3.33Å; S188-F190 PolarHBondContact O-N 3.19Å
191	L	90.6	Very high	79.3	Confident	1 Å²	1	66.6 Å²	66.6	1%	0.005	32%	0.318	C	S	.	.	S	Bend	trans	-62.6	129.7	172.4	-75.3	172.8	0	0	0	110.1	I19 L20 K81 I84 Y127 F187 S188	I19-L191 HydrophobicContact CB-CD2 4.14Å; I19-L191 HydrophobicContact CG2-CD2 3.69Å; I19-L191 HydrophobicContact CG2-CG 3.96Å; L20-L191 HydrophobicContact CB-CD2 4.11Å; L20-L191 HydrophobicContact CD1-CD1 4.4Å; L20-L191 HydrophobicContact CD1-CD2 4.12Å; K81-L191 HydrophobicContact CD-CB 4.49Å; K81-L191 VanDerWaalsContact CD-O 3.32Å; K81-L191 WeakPolarHBondContact CD-O 3.31Å; K81-L191 WeakPolarHBondContact CE-O 3.32Å; K81-L191 PolarHBondContact NZ-O 3.5Å; I84-L191 HydrophobicContact CD1-CD1 4.09Å; I84-L191 HydrophobicContact CG2-CD1 3.88Å; Y127-L191 HydrophobicContact CE1-CD2 4Å; F187-L191 PolarHBondContact O-N 3.01Å; S188-L191 PolarHBondContact O-N 3.27Å
192	P	88.1	Confident	77	Confident	36 Å²	36	69.4 Å²	69.4	23%	0.234	34%	0.341	C	S	.	.	P	Polyproline II helix	trans	-65.1	148.3	174.1	23.8	-31	0	0	0	111.3	P16 Y127 M131 P194	P16-P192 HydrophobicContact CB-CG 3.86Å; P16-P192 HydrophobicContact CG-CG 3.91Å; Y127-P192 WeakPolarHBondContact OH-CD 3.41Å; Y127-P192 WeakPolarHBondContact OH-CG 3.22Å; Y127-P192 PolarHBondContact OH-O 2.9Å; M131-P192 HydrophobicContact CE-CB 3.85Å; M131-P192 HydrophobicContact CE-CG 3.41Å; M131-P192 VanDerWaalsContact CE-CG 3.41Å; M131-P192 HydrophobicContact SD-CG 4.27Å; P192-P194 WeakPolarHBondContact O-CD 3.33Å
193	M	84.1	Confident	74.2	Confident	97 Å²	97	73.8 Å²	73.8	48%	0.478	35%	0.352	S	S	.	.	P	Polyproline II helix	trans	-74.2	124.5	172.1	-77.5	-65.3	-67.3	0	0	109.7	R79 K81	R79-M193 HydrophobicContact CB-CE 4.25Å; K81-M193 HydrophobicContact CB-SD 3.55Å; K81-M193 VanDerWaalsContact CB-SD 3.55Å; K81-M193 HydrophobicContact CD-CG 4.05Å; K81-M193 HydrophobicContact CD-SD 3.44Å; K81-M193 WeakPolarHBondContact CD-SD 3.18Å; K81-M193 HydrophobicContact CG-SD 4Å
194	P	72.9	Confident	71.2	Confident	1 Å²	1	75.7 Å²	75.7	1%	0.006	37%	0.368	C	S	.	.	P	Polyproline II helix	trans	-60.8	137.7	172.7	-21.8	34.4	0	0	0	111.1	R79 Y80 Y127 S130 M131 P192	R79-P194 VanDerWaalsContact CD-O 3.31Å; R79-P194 WeakPolarHBondContact CD-O 3.4Å; R79-P194 VanDerWaalsContact O-CD 3.3Å; R79-P194 WeakPolarHBondContact O-CD 3.25Å; Y80-P194 HydrophobicContact CD2-CB 4.27Å; Y80-P194 HydrophobicContact CD2-CG 3.98Å; Y127-P194 HydrophobicContact CD2-CG 3.86Å; Y127-P194 HydrophobicContact CE2-CG 3.57Å; S130-P194 WeakPolarHBondContact OG-CB 3.38Å; S130-P194 WeakPolarHBondContact OG-CG 3.2Å; M131-P194 HydrophobicContact CG-CB 4.48Å; M131-P194 HydrophobicContact CG-CG 4.09Å; M131-P194 VanDerWaalsContact SD-CA 3.54Å; M131-P194 HydrophobicContact SD-CB 3.91Å; M131-P194 HydrophobicContact SD-CG 3.83Å; P192-P194 WeakPolarHBondContact O-CD 3.33Å
195	K	65.9	Low	68.2	Low	186 Å²	186	80.1 Å²	80.1	81%	0.809	39%	0.392	S	S	*	.	S	Bend	trans	-84.1	-28.1	176.3	-67.2	-172.9	179.9	-176.6	0	112.4
196	K	60.6	Low	65.4	Low	126 Å²	126	86.9 Å²	86.9	55%	0.548	42%	0.415	S	S	.	.			trans	-102.7	136.7	-176	-59.6	-170.4	174.8	-156.4	0	110.5	D205	K196-D205 VanDerWaalsContact CE-OD2 3.26Å; K196-D205 WeakPolarHBondContact CE-OD2 3.41Å; K196-D205 IonicContact NZ-OD2 3.52Å; K196-D205 PolarHBondContact NZ-OD2 3.34Å
197	S	59.4	Low	62.5	Low	7 Å²	7	88.8 Å²	88.8	5%	0.049	43%	0.43	C	S	.	.			trans	-100.4	144.8	160.9	108.8	0	0	0	0	107.9	D76 F200 H201	D76-S197 WeakPolarHBondContact OD1-CB 3.42Å; D76-S197 WeakPolarHBondContact OD2-CB 3.38Å; D76-S197 PolarHBondContact OD2-OG 3.46Å; S197-F200 PolarHBondContact OG-N 3.24Å; S197-H201 PolarHBondContact OG-N 2.96Å; S197-H201 VanDerWaalsContact OG-N 3.08Å; S197-H201 PolarHBondContact OG-ND1 2.98Å; S197-H201 VanDerWaalsContact OG-ND1 3.12Å
198	M	53.6	Low	59.4	Low	83 Å²	83	93.7 Å²	93.7	41%	0.409	46%	0.458	S	S	.	.	S	Bend	trans	-78.1	-31.2	-174.1	-76.1	-162.5	-72.6	0	0	112.5	D76 Y80 A126	D76-M198 PolarHBondContact OD1-N 2.95Å; Y80-M198 HydrophobicContact CE1-CE 4.35Å; Y80-M198 WeakPolarHBondContact OH-CE 3.12Å; Y80-M198 WeakPolarHBondContact OH-CG 3.3Å; A126-M198 HydrophobicContact CB-CE 4.34Å
199	F	51.2	Low	56.1	Low	98 Å²	98	99.2 Å²	99.2	43%	0.43	50%	0.495	S	S	.	.	S	Bend	trans	-109.3	-47.1	-174	-75.5	-84.4	0	0	0	113.8	F72 D76	F72-F199 HydrophobicContact CZ-CE2 4.44Å; D76-F199 PolarHBondContact OD1-N 3.44Å; D76-F199 PolarHBondContact OD2-N 2.83Å
200	F	46.6	Very low	53.2	Low	140 Å²	140	100.9 Å²	100.9	61%	0.614	51%	0.511	S	S	*	.	S	Bend	trans	-91.4	-25	-169.5	-66.5	-70.6	0	0	0	115.7	D76 S197	D76-F200 HydrophobicContact CB-CD2 4.17Å; D76-F200 HydrophobicContact CB-CE2 4.43Å; D76-F200 WeakPolarHBondContact OD2-CD2 3.4Å; D76-F200 PolarHBondContact OD2-N 2.84Å; S197-F200 PolarHBondContact OG-N 3.24Å
201	H	40.1	Very low	50	Low	93 Å²	93	105.5 Å²	105.5	43%	0.431	53%	0.531	S	S	.	.			trans	-112.8	16.7	-170.9	-65	89.3	0	0	0	115.7	S197 K203	S197-H201 PolarHBondContact OG-N 2.96Å; S197-H201 VanDerWaalsContact OG-N 3.08Å; S197-H201 PolarHBondContact OG-ND1 2.98Å; S197-H201 VanDerWaalsContact OG-ND1 3.12Å; H201-K203 PolarHBondContact O-N 3.12Å
202	A	46.4	Very low	47.1	Very low	62 Å²	62	111.5 Å²	111.5	51%	0.512	57%	0.57	S	S	.	*	G	3₁₀ helix	trans	-59.6	-15.7	179.4	0	0	0	0	0	114.5
203	K	37.1	Very low	44.2	Very low	158 Å²	158	118 Å²	118	69%	0.687	60%	0.602	S	S	*	*	G	3₁₀ helix	trans	-75.6	-18.6	-173	-72.9	-173.3	179.2	177.7	0	115.8	H201	H201-K203 PolarHBondContact O-N 3.12Å
204	S	34.8	Very low	41.3	Very low	95 Å²	95	121.5 Å²	121.5	66%	0.664	62%	0.617	S	S	*	*	G	3₁₀ helix	trans	-80.9	-18.1	-175.3	87	0	0	0	0	115.2
205	D	33.9	Very low	38.9	Very low	93 Å²	93	129.8 Å²	129.8	50%	0.497	66%	0.656	S	S	.	*	S	Bend	trans	-99.2	-7.3	-176.4	-96	1.2	0	0	0	113.4	K196 D207	K196-D205 VanDerWaalsContact CE-OD2 3.26Å; K196-D205 WeakPolarHBondContact CE-OD2 3.41Å; K196-D205 IonicContact NZ-OD2 3.52Å; K196-D205 PolarHBondContact NZ-OD2 3.34Å; D205-D207 VanDerWaalsContact C-N 3.29Å; D205-D207 PolarHBondContact O-N 3.17Å
206	R	35.5	Very low	36.7	Very low	223 Å²	223	127.5 Å²	127.5	84%	0.842	66%	0.661	S	S	*	*	S	Bend	trans	-76.8	-15.7	177.2	-76.5	-168.4	179.1	-172.8	1.4	113.5
207	D	34.9	Very low	34.9	Very low	153 Å²	153	127.8 Å²	127.8	82%	0.818	67%	0.674	S	S	*	*	S	Bend	trans	-99.6	-4.3	-178.4	-77.3	-23.1	0	0	0	114.8	D205	D205-D207 VanDerWaalsContact C-N 3.29Å; D205-D207 PolarHBondContact O-N 3.17Å
208	D	31.2	Very low	33	Very low	139 Å²	139	133.1 Å²	133.1	74%	0.743	71%	0.706	S	S	*	*			trans	-117.4	29.4	-171.1	-121.3	2.1	0	0	0	115	P210	D208-P210 WeakPolarHBondContact O-CD 3.43Å
209	C	24.2	Very low	31.5	Very low	115 Å²	115	135.1 Å²	135.1	78%	0.777	73%	0.725	S	S	*	*			trans	-108.6	99.5	169.9	-151.2	0	0	0	0	110.4	K211	C209-K211 PolarHBondContact O-N 3.49Å
210	P	33.1	Very low	29.9	Very low	116 Å²	116	139.4 Å²	139.4	75%	0.753	74%	0.743	S	S	*	*			trans	-67.2	134.4	172.8	-11.4	26.2	0	0	0	109.6	D208	D208-P210 WeakPolarHBondContact O-CD 3.43Å
211	K	26.5	Very low	28.6	Very low	194 Å²	194	141.8 Å²	141.8	84%	0.843	76%	0.757	S	S	*	*			trans	-44.1	132.9	-179.6	-68.5	173.9	177.5	176.7	0	111.7	C209 L213	C209-K211 PolarHBondContact O-N 3.49Å; K211-L213 PolarHBondContact O-N 3.49Å
212	P	29.6	Very low	27.9	Very low	126 Å²	126	142.1 Å²	142.1	82%	0.818	78%	0.775	S	S	*	*	P	Polyproline II helix	trans	-65.6	126.5	-171.4	23.7	-30.9	0	0	0	111.4	E214	P212-E214 PolarHBondContact O-N 2.92Å
213	L	26.5	Very low	26.6	Very low	173 Å²	173	149.1 Å²	149.1	91%	0.906	80%	0.797	S	S	*	*	P	Polyproline II helix	trans	-59.6	130.2	168.9	-96.1	95.2	0	0	0	110.1	K211	K211-L213 PolarHBondContact O-N 3.49Å
214	E	24	Very low	26	Very low	170 Å²	170	147.1 Å²	147.1	79%	0.794	80%	0.803	S	S	*	*	P	Polyproline II helix	trans	-57.8	150.3	168.7	-72	176.8	130.7	0	0	112.4	P212	P212-E214 PolarHBondContact O-N 2.92Å
215	Q	22	Very low	25.3	Very low	176 Å²	176	149.3 Å²	149.3	82%	0.822	81%	0.807	S	S	*	*			trans	70.6	94.1	158.5	-68.1	170	4.7	0	0	117.3
216	C	20.5	Very low	24.8	Very low	137 Å²	137	155.1 Å²	155.1	93%	0.926	82%	0.822	S	S	*	*			trans	-137.4	127.9	138.3	-105	0	0	0	0	111.5
217	T	21.6	Very low	24.1	Very low	133 Å²	133	150.5 Å²	150.5	82%	0.816	82%	0.819	S	S	*	*	P	Polyproline II helix	trans	-68.9	140.3	-165.4	-48	0	0	0	0	112.9	P219	T217-P219 WeakPolarHBondContact O-CD 3.39Å
218	V	19.3	Very low	23.5	Very low	119 Å²	119	152 Å²	152	72%	0.721	82%	0.821	S	S	*	*	P	Polyproline II helix	trans	-48.5	129.4	175.4	178.7	0	0	0	0	113.6	K220	V218-K220 HydrophobicContact CG1-CG 4.37Å
219	P	21.9	Very low	23.2	Very low	124 Å²	124	151 Å²	151	81%	0.805	83%	0.825	S	S	*	*	P	Polyproline II helix	trans	-103.5	120.8	148	6.4	14.2	0	0	0	109.7	T217	T217-P219 WeakPolarHBondContact O-CD 3.39Å
220	K	19.1	Very low	23.4	Very low	188 Å²	188	153.4 Å²	153.4	82%	0.817	83%	0.825	S	S	*	*	P	Polyproline II helix	trans	-68.8	133.3	168.6	-71.1	171.8	172.4	174.1	0	109.5	V218	V218-K220 HydrophobicContact CG1-CG 4.37Å
221	E	19.7	Very low	22.9	Very low	191 Å²	191	155.7 Å²	155.7	89%	0.893	83%	0.83	S	S	*	*			trans	155.4	111.5	130.7	-88.6	177.9	173.5	0	0	111.2
222	A	24.7	Very low	22.7	Very low	100 Å²	100	155.1 Å²	155.1	83%	0.826	83%	0.828	S	S	*	*			trans	167.9	89	140.9	0	0	0	0	0	108.1	S224	A222-S224 PolarHBondContact O-N 3.08Å; A222-S224 VanDerWaalsContact O-N 3.13Å
223	Q	19.8	Very low	22.5	Very low	209 Å²	209	153.6 Å²	153.6	98%	0.977	83%	0.825	S	S	*	*			trans	-67.2	103.2	168	-75.5	171.3	-17.6	0	0	109
224	S	23.1	Very low	22.3	Very low	115 Å²	115	152.6 Å²	152.6	80%	0.804	82%	0.821	S	S	*	*			trans	-128.6	102.5	159.1	-177.9	0	0	0	0	109.5	A222	A222-S224 PolarHBondContact O-N 3.08Å; A222-S224 VanDerWaalsContact O-N 3.13Å
225	N	21.2	Very low	22.4	Very low	141 Å²	141	150.2 Å²	150.2	75%	0.754	82%	0.823	S	S	*	*			trans	-22.8	134.4	168.3	-77.4	-38.2	0	0	0	118
226	R	22.2	Very low	22.5	Very low	215 Å²	215	150.6 Å²	150.6	81%	0.811	82%	0.822	S	S	*	*			trans	89.6	94.4	142.4	-69.8	175.3	-173.9	-173.9	1.6	119.1
227	T	21.6	Very low	22.7	Very low	127 Å²	127	150.7 Å²	150.7	78%	0.779	81%	0.813	S	S	*	*				50	85	124.7	42.7	0	0	0	0	117.2
228	H	22.7	Very low	22.9	Very low	185 Å²	185	153 Å²	153	86%	0.856	82%	0.819	S	S	*	*			trans	-111.3	101.2	137.1	-82.5	-90.5	0	0	0	106.8	E230	H228-E230 PolarHBondContact O-N 2.88Å; H228-E230 VanDerWaalsContact O-N 3.15Å
229	S	24.7	Very low	23.2	Very low	117 Å²	117	154.7 Å²	154.7	82%	0.818	82%	0.82	S	S	*	*			trans	-59.9	114.7	176.6	-164.5	0	0	0	0	108.2	L231	S229-L231 PolarHBondContact O-N 2.7Å
230	E	27.3	Very low	23.4	Very low	166 Å²	166	156 Å²	156	78%	0.776	82%	0.82	S	S	*	*			trans	-55.6	119	176.8	-67.4	175.7	160	0	0	109.9	H228 F232	H228-E230 PolarHBondContact O-N 2.88Å; H228-E230 VanDerWaalsContact O-N 3.15Å; E230-F232 VanDerWaalsContact C-N 3.25Å; E230-F232 HydrophobicContact CB-CD2 4.18Å; E230-F232 PolarHBondContact O-N 3.5Å; E230-F232 VanDerWaalsContact O-N 3.15Å
231	L	22.7	Very low	23.7	Very low	164 Å²	164	159 Å²	159	86%	0.859	83%	0.826	S	S	*	*			trans	-88.9	64.3	-178.9	-146.1	153.3	0	0	0	108.1	S229	S229-L231 PolarHBondContact O-N 2.7Å
232	F	23.7	Very low	24.1	Very low	182 Å²	182	158.4 Å²	158.4	80%	0.798	82%	0.823	S	S	*	*			trans	-109	76.6	170	-74.2	-74.1	0	0	0	108.7	E230 N234	E230-F232 VanDerWaalsContact C-N 3.25Å; E230-F232 HydrophobicContact CB-CD2 4.18Å; E230-F232 PolarHBondContact O-N 3.5Å; E230-F232 VanDerWaalsContact O-N 3.15Å; F232-N234 PolarHBondContact O-N 2.86Å; F232-N234 VanDerWaalsContact O-N 3.14Å
233	A	25.3	Very low	24.2	Very low	93 Å²	93	162.5 Å²	162.5	77%	0.769	83%	0.827	S	S	*	*			trans	-74.1	103.2	173.9	0	0	0	0	0	109.9	S235	A233-S235 PolarHBondContact O-N 3.43Å; A233-S235 VanDerWaalsContact O-N 3.14Å
234	N	22.4	Very low	24.7	Very low	152 Å²	152	157.2 Å²	157.2	81%	0.813	81%	0.814	S	S	*	*			trans	-3.6	94.7	153.6	-68.2	-25.8	0	0	0	115.9	F232 K236	F232-N234 PolarHBondContact O-N 2.86Å; F232-N234 VanDerWaalsContact O-N 3.14Å; N234-K236 PolarHBondContact O-N 3.47Å; N234-K236 VanDerWaalsContact O-N 3.15Å
235	S	25.8	Very low	25.2	Very low	121 Å²	121	159.2 Å²	159.2	85%	0.846	82%	0.815	S	S	*	*			trans	-72.4	100.1	154.7	-178.6	0	0	0	0	107.3	A233 N237	A233-S235 PolarHBondContact O-N 3.43Å; A233-S235 VanDerWaalsContact O-N 3.14Å; S235-N237 PolarHBondContact O-N 3.17Å
236	K	23.5	Very low	26.2	Very low	184 Å²	184	156.5 Å²	156.5	80%	0.8	81%	0.805	S	S	*	*			trans	-61.6	124.7	174.3	-82.4	177.7	171.5	178	0	110.1	N234 L238	N234-K236 PolarHBondContact O-N 3.47Å; N234-K236 VanDerWaalsContact O-N 3.15Å; K236-L238 PolarHBondContact O-N 3.37Å
237	N	23.6	Very low	27.3	Very low	138 Å²	138	151.7 Å²	151.7	74%	0.738	80%	0.796	S	S	*	*			trans	7	103	149.6	-57.3	-2.8	0	0	0	115.5	S235	S235-N237 PolarHBondContact O-N 3.17Å
238	L	26.6	Very low	28.7	Very low	181 Å²	181	150.6 Å²	150.6	95%	0.948	79%	0.791	S	S	*	*			trans	-119	74.2	153.1	-138.2	102	0	0	0	106.7	K236	K236-L238 PolarHBondContact O-N 3.37Å
239	E	25	Very low	30.2	Very low	155 Å²	155	149.6 Å²	149.6	72%	0.724	79%	0.787	S	S	*	*			trans	-78.9	137.6	169.3	-77.7	177.8	155.9	0	0	109.7
240	D	25.8	Very low	31.9	Very low	151 Å²	151	148.2 Å²	148.2	81%	0.807	77%	0.77	S	S	*	*			trans	65.1	92.2	150.9	-55.4	-20.5	0	0	0	119.3
241	R	26.5	Very low	33.7	Very low	252 Å²	252	142.2 Å²	142.2	95%	0.951	75%	0.746	S	S	*	*			trans	-139.6	121	139.5	-147.6	170.4	-175.3	170.7	1.1	111.8
242	E	27.7	Very low	36.1	Very low	179 Å²	179	137.2 Å²	137.2	84%	0.836	73%	0.729	S	S	*	*			trans	-56.3	137.8	-167.2	-64.3	163.3	138.7	0	0	115.9	S244	E242-S244 PolarHBondContact O-N 3.43Å
243	M	28	Very low	38.5	Very low	185 Å²	185	134.6 Å²	134.6	91%	0.911	72%	0.722	S	S	*	*			trans	19.6	93.8	136.5	-157.6	85.5	91.3	0	0	117.3
244	S	30.6	Very low	40.9	Very low	99 Å²	99	137.5 Å²	137.5	69%	0.692	71%	0.714	S	S	*	*			trans	-142.7	121.4	149	47	0	0	0	0	108	E242 P246	E242-S244 PolarHBondContact O-N 3.43Å; S244-P246 WeakPolarHBondContact O-CD 3.47Å
245	N	32.7	Very low	43.3	Very low	156 Å²	156	135.1 Å²	135.1	83%	0.834	70%	0.697	S	S	*	*			trans	-50.2	109	179.9	-80	-25.5	0	0	0	109.5	D247	N245-D247 PolarHBondContact O-N 3.38Å
246	P	42.8	Very low	45.7	Very low	84 Å²	84	135.6 Å²	135.6	55%	0.545	69%	0.685	S	S	.	*			trans	-85	122.3	-175.1	29.6	-25.8	0	0	0	109.1	S244	S244-P246 WeakPolarHBondContact O-CD 3.47Å
247	D	44.1	Very low	48.4	Very low	115 Å²	115	129.3 Å²	129.3	62%	0.615	67%	0.667	S	S	*	*			trans	-47.8	135.3	165.8	-69.1	-51.4	0	0	0	110	N245 E249 N250 S251	N245-D247 PolarHBondContact O-N 3.38Å; D247-E249 PolarHBondContact O-N 2.92Å; D247-E249 VanDerWaalsContact O-N 3.08Å; D247-N250 PolarHBondContact O-N 3.49Å; D247-S251 PolarHBondContact O-N 2.84Å
248	P	52.3	Low	51	Low	103 Å²	103	128.3 Å²	128.3	67%	0.669	66%	0.657	S	S	*	*	H	α-helix	trans	-57.7	-30.9	-171.3	19.2	-30.6	0	0	0	113.1	S251 A252	P248-S251 WeakPolarHBondContact O-CB 3.5Å; P248-S251 PolarHBondContact O-N 2.76Å; P248-S251 PolarHBondContact O-OG 2.84Å; P248-A252 PolarHBondContact O-N 3.13Å
249	E	54	Low	53.6	Low	165 Å²	165	124.3 Å²	124.3	77%	0.771	63%	0.63	S	S	*	*	H	α-helix	trans	-62.5	-41.6	177.3	-106.8	-176.8	157.4	0	0	113	D247 S251 A252 L253	D247-E249 PolarHBondContact O-N 2.92Å; D247-E249 VanDerWaalsContact O-N 3.08Å; E249-S251 PolarHBondContact O-N 3.43Å; E249-A252 PolarHBondContact O-N 2.93Å; E249-L253 PolarHBondContact O-N 3.23Å
250	N	60	Low	56.3	Low	87 Å²	87	122.3 Å²	122.3	47%	0.465	62%	0.619	S	S	.	*	H	α-helix	trans	-68.7	-25.7	177.1	-86.9	-25	0	0	0	112.1	D247 R254	D247-N250 PolarHBondContact O-N 3.49Å; N250-R254 WeakPolarHBondContact O-CB 3.48Å; N250-R254 VanDerWaalsContact O-CG 3.23Å; N250-R254 WeakPolarHBondContact O-CG 3.46Å; N250-R254 PolarHBondContact O-N 3.18Å; N250-R254 VanDerWaalsContact O-N 3.17Å
251	S	65.3	Low	59	Low	40 Å²	40	120 Å²	120	28%	0.28	60%	0.603	S	S	.	*	H	α-helix	trans	-67.8	-50.2	176.7	84.2	0	0	0	0	110.9	D247 P248 E249 L253 R254 H255	D247-S251 PolarHBondContact O-N 2.84Å; P248-S251 WeakPolarHBondContact O-CB 3.5Å; P248-S251 PolarHBondContact O-N 2.76Å; P248-S251 PolarHBondContact O-OG 2.84Å; E249-S251 PolarHBondContact O-N 3.43Å; S251-L253 VanDerWaalsContact C-N 3.33Å; S251-L253 PolarHBondContact O-N 2.82Å; S251-R254 PolarHBondContact O-N 3.03Å; S251-H255 VanDerWaalsContact C-ND1 3.29Å; S251-H255 PolarHBondContact O-CE1 3.21Å; S251-H255 VanDerWaalsContact O-CG 3.32Å; S251-H255 PolarHBondContact O-N 3.47Å; S251-H255 PolarHBondContact O-ND1 3.43Å
252	A	72.4	Confident	61.7	Low	60 Å²	60	110.8 Å²	110.8	50%	0.496	57%	0.573	S	S	.	*	H	α-helix	trans	-61.3	-42.9	-177.4	0	0	0	0	0	111.8	P248 E249 R254 H255 F256	P248-A252 PolarHBondContact O-N 3.13Å; E249-A252 PolarHBondContact O-N 2.93Å; A252-R254 PolarHBondContact O-N 3.37Å; A252-H255 PolarHBondContact O-N 3.39Å; A252-F256 PolarHBondContact O-N 3.2Å
253	L	74.7	Confident	64.3	Low	126 Å²	126	103.6 Å²	103.6	66%	0.66	54%	0.54	S	S	*	.	H	α-helix	trans	-66.9	-37.4	179.8	-145.7	143.3	0	0	0	111.8	E249 S251 F256 A257	E249-L253 PolarHBondContact O-N 3.23Å; S251-L253 VanDerWaalsContact C-N 3.33Å; S251-L253 PolarHBondContact O-N 2.82Å; L253-F256 PolarHBondContact O-N 2.91Å; L253-A257 WeakPolarHBondContact O-CB 3.36Å; L253-A257 PolarHBondContact O-N 3.22Å
254	R	74.8	Confident	67	Low	155 Å²	155	101.9 Å²	101.9	59%	0.585	53%	0.527	S	S	*	.	H	α-helix	trans	-65.3	-43.1	171.2	-75.6	178.4	-167.9	-172.7	6.1	112.4	N250 S251 A252 F256 A257 H258	N250-R254 WeakPolarHBondContact O-CB 3.48Å; N250-R254 VanDerWaalsContact O-CG 3.23Å; N250-R254 WeakPolarHBondContact O-CG 3.46Å; N250-R254 PolarHBondContact O-N 3.18Å; N250-R254 VanDerWaalsContact O-N 3.17Å; S251-R254 PolarHBondContact O-N 3.03Å; A252-R254 PolarHBondContact O-N 3.37Å; R254-F256 VanDerWaalsContact C-N 3.34Å; R254-F256 PolarHBondContact O-N 3.46Å; R254-A257 PolarHBondContact O-N 3.49Å; R254-H258 PolarHBondContact O-CD2 3.23Å; R254-H258 PolarHBondContact O-N 2.83Å
255	H	73.8	Confident	69.5	Low	102 Å²	102	101.1 Å²	101.1	47%	0.472	51%	0.513	S	S	.	.	H	α-helix	trans	-62.7	-42.5	176.8	-62.4	115.7	0	0	0	111.1	S251 A252 H258 W259	S251-H255 VanDerWaalsContact C-ND1 3.29Å; S251-H255 PolarHBondContact O-CE1 3.21Å; S251-H255 VanDerWaalsContact O-CG 3.32Å; S251-H255 PolarHBondContact O-N 3.47Å; S251-H255 PolarHBondContact O-ND1 3.43Å; A252-H255 PolarHBondContact O-N 3.39Å; H255-H258 PolarHBondContact O-N 2.89Å; H255-W259 VanDerWaalsContact O-CB 3.29Å; H255-W259 WeakPolarHBondContact O-CB 3.27Å; H255-W259 PolarHBondContact O-N 3.23Å
256	F	76.1	Confident	71.8	Confident	131 Å²	131	94 Å²	94	58%	0.575	48%	0.475	S	S	*	.	H	α-helix	trans	-63.9	-41.2	174.8	-176	-98.8	0	0	0	112	A252 L253 R254 W259 F260	A252-F256 PolarHBondContact O-N 3.2Å; L253-F256 PolarHBondContact O-N 2.91Å; R254-F256 VanDerWaalsContact C-N 3.34Å; R254-F256 PolarHBondContact O-N 3.46Å; F256-W259 HydrophobicContact CD2-CE3 4.19Å; F256-W259 AromaticContact CE2-CE3 3.98Å; F256-W259 HydrophobicContact CE2-CE3 3.98Å; F256-W259 AromaticContact CE2-CZ3 3.97Å; F256-W259 HydrophobicContact CE2-CZ3 3.97Å; F256-W259 HydrophobicContact CZ-CZ3 4.44Å; F256-W259 PolarHBondContact O-N 3.15Å; F256-F260 WeakPolarHBondContact O-CB 3.45Å; F256-F260 PolarHBondContact O-N 3.13Å
257	A	79.8	Confident	73.9	Confident	51 Å²	51	92.7 Å²	92.7	42%	0.421	46%	0.46	S	S	.	.	H	α-helix	trans	-63.1	-43.9	176.2	0	0	0	0	0	112.3	L253 R254 F260 Q261	L253-A257 WeakPolarHBondContact O-CB 3.36Å; L253-A257 PolarHBondContact O-N 3.22Å; R254-A257 PolarHBondContact O-N 3.49Å; A257-F260 PolarHBondContact O-N 3.35Å; A257-Q261 WeakPolarHBondContact O-CB 3.21Å; A257-Q261 PolarHBondContact O-N 3.4Å
258	H	79.3	Confident	75.9	Confident	117 Å²	117	91.4 Å²	91.4	54%	0.542	46%	0.46	S	S	.	.	H	α-helix	trans	-62.4	-46.7	174	-80	-61.9	0	0	0	111.8	R254 H255 F260 Q261 D262	R254-H258 PolarHBondContact O-CD2 3.23Å; R254-H258 PolarHBondContact O-N 2.83Å; H255-H258 PolarHBondContact O-N 2.89Å; H258-F260 VanDerWaalsContact C-N 3.31Å; H258-F260 PolarHBondContact O-N 3.41Å; H258-Q261 PolarHBondContact O-N 3.32Å; H258-Q261 VanDerWaalsContact O-N 3.14Å; H258-D262 PolarHBondContact O-N 3.32Å
259	W	80.5	Confident	77.5	Confident	97 Å²	97	89 Å²	89	37%	0.367	45%	0.445	S	S	.	.	H	α-helix	trans	-57.6	-43.1	176	177.5	87.6	0	0	0	112.3	H255 F256 D262 L263 L399 I403	H255-W259 VanDerWaalsContact O-CB 3.29Å; H255-W259 WeakPolarHBondContact O-CB 3.27Å; H255-W259 PolarHBondContact O-N 3.23Å; F256-W259 HydrophobicContact CD2-CE3 4.19Å; F256-W259 AromaticContact CE2-CE3 3.98Å; F256-W259 HydrophobicContact CE2-CE3 3.98Å; F256-W259 AromaticContact CE2-CZ3 3.97Å; F256-W259 HydrophobicContact CE2-CZ3 3.97Å; F256-W259 HydrophobicContact CZ-CZ3 4.44Å; F256-W259 PolarHBondContact O-N 3.15Å; W259-D262 PolarHBondContact O-N 3.4Å; W259-L263 HydrophobicContact CH2-CD2 4.28Å; W259-L263 HydrophobicContact CZ3-CD2 4.34Å; W259-L263 WeakPolarHBondContact O-CB 3.44Å; W259-L263 PolarHBondContact O-N 2.86Å; W259-L399 VanDerWaalsContact CE2-CD1 3.47Å; W259-L399 HydrophobicContact CZ2-CD1 3.54Å; W259-I403 HydrophobicContact CH2-CD1 4.4Å; W259-I403 HydrophobicContact CZ2-CD1 4.2Å
260	F	80.6	Confident	79	Confident	113 Å²	113	88.8 Å²	88.8	50%	0.496	44%	0.442	S	S	.	.	H	α-helix	trans	-70.3	-33.3	177.1	-172.3	-100.7	0	0	0	112.7	F256 A257 H258 L263 K264	F256-F260 WeakPolarHBondContact O-CB 3.45Å; F256-F260 PolarHBondContact O-N 3.13Å; A257-F260 PolarHBondContact O-N 3.35Å; H258-F260 VanDerWaalsContact C-N 3.31Å; H258-F260 PolarHBondContact O-N 3.41Å; F260-L263 HydrophobicContact CD2-CD2 4.31Å; F260-L263 WeakPolarHBondContact O-CB 3.11Å; F260-L263 PolarHBondContact O-N 2.94Å; F260-K264 WeakPolarHBondContact O-CB 3.44Å; F260-K264 PolarHBondContact O-N 3.44Å
261	Q	83.5	Confident	80.3	Confident	103 Å²	103	87.1 Å²	87.1	48%	0.481	43%	0.431	S	S	.	.	H	α-helix	trans	-67.3	-46.9	173.3	-178.2	175.7	-14.5	0	0	111.3	A257 H258 L263 K264 E265	A257-Q261 WeakPolarHBondContact O-CB 3.21Å; A257-Q261 PolarHBondContact O-N 3.4Å; H258-Q261 PolarHBondContact O-N 3.32Å; H258-Q261 VanDerWaalsContact O-N 3.14Å; Q261-L263 PolarHBondContact O-N 2.93Å; Q261-K264 WeakPolarHBondContact O-CB 3.46Å; Q261-K264 PolarHBondContact O-N 3.18Å; Q261-K264 VanDerWaalsContact O-N 3.11Å; Q261-E265 PolarHBondContact NE2-OE1 2.65Å; Q261-E265 VanDerWaalsContact NE2-OE1 3.15Å; Q261-E265 WeakPolarHBondContact O-CG 3.4Å; Q261-E265 PolarHBondContact O-N 2.8Å
262	D	82.1	Confident	81.4	Confident	59 Å²	59	85.5 Å²	85.5	32%	0.316	42%	0.419	S	S	.	.	H	α-helix	trans	-57.4	-40.6	174.4	-83.8	-41	0	0	0	111.2	H258 W259 E265 C266 R396	H258-D262 PolarHBondContact O-N 3.32Å; W259-D262 PolarHBondContact O-N 3.4Å; D262-E265 PolarHBondContact O-N 3.34Å; D262-C266 PolarHBondContact O-N 2.98Å; D262-C266 PolarHBondContact O-SG 3.27Å; D262-R396 IonicContact OD1-CZ 3.62Å; D262-R396 IonicContact OD1-NE 3.7Å; D262-R396 IonicContact OD1-NH2 2.77Å; D262-R396 PolarHBondContact OD1-NH2 2.95Å
263	L	83.7	Confident	82.3	Confident	28 Å²	28	84.6 Å²	84.6	15%	0.147	41%	0.407	C	S	.	.	H	α-helix	trans	-58.5	-50.4	174.1	-179.3	61.2	0	0	0	111.8	W259 F260 Q261 E265 C266 Y267 L399 I403	W259-L263 HydrophobicContact CH2-CD2 4.28Å; W259-L263 HydrophobicContact CZ3-CD2 4.34Å; W259-L263 WeakPolarHBondContact O-CB 3.44Å; W259-L263 PolarHBondContact O-N 2.86Å; F260-L263 HydrophobicContact CD2-CD2 4.31Å; F260-L263 WeakPolarHBondContact O-CB 3.11Å; F260-L263 PolarHBondContact O-N 2.94Å; Q261-L263 PolarHBondContact O-N 2.93Å; L263-E265 VanDerWaalsContact C-N 3.31Å; L263-E265 PolarHBondContact O-N 3.22Å; L263-C266 PolarHBondContact O-N 3.37Å; L263-Y267 HydrophobicContact CD1-CD2 3.51Å; L263-Y267 HydrophobicContact CD1-CE2 3.33Å; L263-Y267 HydrophobicContact CG-CD2 4.22Å; L263-Y267 HydrophobicContact CG-CE2 4.44Å; L263-Y267 WeakPolarHBondContact O-CD2 3.47Å; L263-Y267 PolarHBondContact O-N 3.27Å; L263-Y267 VanDerWaalsContact O-N 3.1Å; L263-L399 HydrophobicContact CB-CD2 4.33Å; L263-L399 HydrophobicContact CD1-CD2 4.4Å; L263-L399 HydrophobicContact CD1-CG 4.45Å; L263-I403 HydrophobicContact CD1-CD1 3.1Å; L263-I403 HydrophobicContact CD2-CD1 3.83Å; L263-I403 HydrophobicContact CG-CD1 4.08Å
264	K	84.3	Confident	83.2	Confident	148 Å²	148	81.8 Å²	81.8	64%	0.643	39%	0.388	S	S	*	.	H	α-helix	trans	-61.4	-40	178.9	-173.5	179.5	178.3	-177.3	0	111.7	F260 Q261 S268	F260-K264 WeakPolarHBondContact O-CB 3.44Å; F260-K264 PolarHBondContact O-N 3.44Å; Q261-K264 WeakPolarHBondContact O-CB 3.46Å; Q261-K264 PolarHBondContact O-N 3.18Å; Q261-K264 VanDerWaalsContact O-N 3.11Å; K264-S268 PolarHBondContact O-N 2.93Å; K264-S268 VanDerWaalsContact O-N 3.09Å; K264-S268 PolarHBondContact O-OG 3.27Å
265	E	83.2	Confident	84	Confident	84 Å²	84	74.8 Å²	74.8	39%	0.393	36%	0.362	S	S	.	.	H	α-helix	trans	-63.4	-43.6	176.1	-73.8	178.8	-163.8	0	0	111.7	Q261 D262 L263 S268 R396	Q261-E265 PolarHBondContact NE2-OE1 2.65Å; Q261-E265 VanDerWaalsContact NE2-OE1 3.15Å; Q261-E265 WeakPolarHBondContact O-CG 3.4Å; Q261-E265 PolarHBondContact O-N 2.8Å; D262-E265 PolarHBondContact O-N 3.34Å; L263-E265 VanDerWaalsContact C-N 3.31Å; L263-E265 PolarHBondContact O-N 3.22Å; E265-S268 WeakPolarHBondContact O-CB 3.26Å; E265-S268 PolarHBondContact O-N 3Å; E265-R396 IonicContact OE2-CZ 2.79Å; E265-R396 IonicContact OE2-NH1 3.55Å; E265-R396 IonicContact OE2-NH2 2.75Å; E265-R396 PolarHBondContact OE2-NH2 3.44Å
266	C	81.6	Confident	85	Confident	6 Å²	6	70.1 Å²	70.1	4%	0.041	34%	0.341	C	S	.	.	H	α-helix	trans	-60.1	-51.2	177.6	-66.7	0	0	0	0	111.6	D262 L263 S268 L392 V400	D262-C266 PolarHBondContact O-N 2.98Å; D262-C266 PolarHBondContact O-SG 3.27Å; L263-C266 PolarHBondContact O-N 3.37Å; C266-S268 PolarHBondContact O-N 3.32Å; C266-L392 HydrophobicContact CB-CD2 4.43Å; C266-V400 HydrophobicContact CB-CG2 3.95Å
267	Y	85	Confident	85.9	Confident	57 Å²	57	67.4 Å²	67.4	22%	0.224	33%	0.332	C	S	.	.	T	Hydrogen-bonded Turn	trans	-80.8	8.4	-179.2	-69	-82.1	0	0	0	114	L263 S269 L272 V273 V400 I403 D404	L263-Y267 HydrophobicContact CD1-CD2 3.51Å; L263-Y267 HydrophobicContact CD1-CE2 3.33Å; L263-Y267 HydrophobicContact CG-CD2 4.22Å; L263-Y267 HydrophobicContact CG-CE2 4.44Å; L263-Y267 WeakPolarHBondContact O-CD2 3.47Å; L263-Y267 PolarHBondContact O-N 3.27Å; L263-Y267 VanDerWaalsContact O-N 3.1Å; Y267-S269 VanDerWaalsContact C-N 3.3Å; Y267-L272 HydrophobicContact CD1-CD2 3.61Å; Y267-L272 HydrophobicContact CE1-CD2 3.79Å; Y267-L272 HydrophobicContact CG-CD2 4.16Å; Y267-V273 HydrophobicContact CD1-CG2 4.04Å; Y267-V273 WeakPolarHBondContact O-CG2 3.32Å; Y267-V400 HydrophobicContact CE2-CG2 4.22Å; Y267-I403 HydrophobicContact CE2-CG2 4.43Å; Y267-D404 PolarHBondContact OH-OD1 3.22Å
268	S	86	Confident	86.7	Confident	87 Å²	87	65 Å²	65	61%	0.608	31%	0.312	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75.5	-21.8	169.7	-67.6	0	0	0	0	112.3	K264 E265 C266 K270	K264-S268 PolarHBondContact O-N 2.93Å; K264-S268 VanDerWaalsContact O-N 3.09Å; K264-S268 PolarHBondContact O-OG 3.27Å; E265-S268 WeakPolarHBondContact O-CB 3.26Å; E265-S268 PolarHBondContact O-N 3Å; C266-S268 PolarHBondContact O-N 3.32Å; S268-K270 PolarHBondContact O-N 3.13Å
269	S	86.2	Confident	87.5	Confident	52 Å²	52	60 Å²	60	36%	0.364	29%	0.288	S	S	.	.			trans	-78.2	115.4	174.2	176.5	0	0	0	0	110.8	Y267 H271 L272 V273	Y267-S269 VanDerWaalsContact C-N 3.3Å; S269-H271 PolarHBondContact O-N 2.87Å; S269-L272 PolarHBondContact O-N 2.9Å; S269-L272 VanDerWaalsContact O-N 3.13Å; S269-V273 WeakPolarHBondContact O-CG2 3.41Å; S269-V273 PolarHBondContact O-N 3.08Å
270	K	86.8	Confident	88.3	Confident	162 Å²	162	55.5 Å²	55.5	70%	0.704	27%	0.272	S	S	*	.	H	α-helix	trans	-53.1	-43.4	175.4	-71.3	-176	-177.9	179	0	111.9	S268 L272 V273 Y274	S268-K270 PolarHBondContact O-N 3.13Å; K270-L272 PolarHBondContact O-N 3.28Å; K270-V273 PolarHBondContact O-N 3.21Å; K270-Y274 HydrophobicContact CB-CD2 4.49Å; K270-Y274 HydrophobicContact CB-CE2 4.02Å; K270-Y274 WeakPolarHBondContact O-CD2 3.12Å; K270-Y274 WeakPolarHBondContact O-CE2 3.2Å; K270-Y274 PolarHBondContact O-N 3.46Å; K270-Y274 VanDerWaalsContact O-N 3.12Å
271	H	86.5	Confident	89.2	Confident	52 Å²	52	54 Å²	54	24%	0.241	27%	0.265	C	S	.	.	H	α-helix	trans	-57.3	-50.7	178.6	-179.8	-96.2	0	0	0	111.2	S269 V273 Y274 W275 D336 Q387	S269-H271 PolarHBondContact O-N 2.87Å; H271-V273 PolarHBondContact O-N 3.15Å; H271-Y274 PolarHBondContact O-N 3.35Å; H271-W275 AromaticContact CD2-CD1 3.84Å; H271-W275 AromaticContact CD2-NE1 3.6Å; H271-W275 AromaticContact CE1-CD1 3.32Å; H271-W275 AromaticContact CE1-NE1 3.24Å; H271-W275 PolarHBondContact CE1-NE1 2.94Å; H271-W275 AromaticContact CG-CD1 3.98Å; H271-W275 AromaticContact ND1-CD1 3.66Å; H271-W275 AromaticContact ND1-NE1 3.98Å; H271-W275 AromaticContact NE2-CD1 3.4Å; H271-W275 AromaticContact NE2-NE1 2.9Å; H271-W275 PolarHBondContact NE2-NE1 2.71Å; H271-W275 VanDerWaalsContact O-CD1 3.23Å; H271-W275 PolarHBondContact O-N 3.18Å; H271-D336 IonicContact NE2-OD1 3.88Å; H271-Q387 PolarHBondContact CE1-OE1 3.41Å
272	L	88.3	Confident	89.9	Confident	6 Å²	6	49 Å²	49	3%	0.031	24%	0.242	C	C	.	.	H	α-helix	trans	-60	-45.7	179.1	-173.8	151.4	0	0	0	111.3	Y267 S269 K270 Y274 W275 S276 L392 V400	Y267-L272 HydrophobicContact CD1-CD2 3.61Å; Y267-L272 HydrophobicContact CE1-CD2 3.79Å; Y267-L272 HydrophobicContact CG-CD2 4.16Å; S269-L272 PolarHBondContact O-N 2.9Å; S269-L272 VanDerWaalsContact O-N 3.13Å; K270-L272 PolarHBondContact O-N 3.28Å; L272-Y274 VanDerWaalsContact C-N 3.34Å; L272-Y274 PolarHBondContact O-N 3.47Å; L272-W275 PolarHBondContact O-N 2.95Å; L272-S276 WeakPolarHBondContact CD2-OG 3.48Å; L272-S276 VanDerWaalsContact O-CB 3.26Å; L272-S276 WeakPolarHBondContact O-CB 3.48Å; L272-S276 PolarHBondContact O-N 3.26Å; L272-S276 PolarHBondContact O-OG 2.88Å; L272-L392 HydrophobicContact CD1-CD1 3.79Å; L272-L392 HydrophobicContact CD1-CD2 3.64Å; L272-L392 HydrophobicContact CD1-CG 3.89Å; L272-V400 HydrophobicContact CD2-CG1 4.4Å
273	V	91.9	Very high	90.6	Very high	40 Å²	40	46.9 Å²	46.9	24%	0.242	23%	0.231	C	C	.	.	H	α-helix	trans	-56.2	-46.2	179	172.5	0	0	0	0	111.5	Y267 S269 K270 H271 S276 L277	Y267-V273 HydrophobicContact CD1-CG2 4.04Å; Y267-V273 WeakPolarHBondContact O-CG2 3.32Å; S269-V273 WeakPolarHBondContact O-CG2 3.41Å; S269-V273 PolarHBondContact O-N 3.08Å; K270-V273 PolarHBondContact O-N 3.21Å; H271-V273 PolarHBondContact O-N 3.15Å; V273-S276 PolarHBondContact O-N 3.38Å; V273-L277 HydrophobicContact CG1-CD1 3.75Å; V273-L277 HydrophobicContact CG1-CG 4.2Å; V273-L277 WeakPolarHBondContact O-CB 2.92Å; V273-L277 WeakPolarHBondContact O-CG 3.45Å; V273-L277 PolarHBondContact O-N 3.41Å
274	Y	92.3	Very high	91.3	Very high	67 Å²	67	45.6 Å²	45.6	26%	0.263	22%	0.224	S	C	.	.	H	α-helix	trans	-68.3	-40.8	-177.4	-67.5	-60.5	0	0	0	113.3	K270 H271 L272 W278 R450	K270-Y274 HydrophobicContact CB-CD2 4.49Å; K270-Y274 HydrophobicContact CB-CE2 4.02Å; K270-Y274 WeakPolarHBondContact O-CD2 3.12Å; K270-Y274 WeakPolarHBondContact O-CE2 3.2Å; K270-Y274 PolarHBondContact O-N 3.46Å; K270-Y274 VanDerWaalsContact O-N 3.12Å; H271-Y274 PolarHBondContact O-N 3.35Å; L272-Y274 VanDerWaalsContact C-N 3.34Å; L272-Y274 PolarHBondContact O-N 3.47Å; Y274-W278 PolarHBondContact O-N 3.45Å; Y274-R450 VanDerWaalsContact CE1-CZ 3.4Å; Y274-R450 PolarHBondContact OH-NH1 3.41Å
275	W	93.4	Very high	92	Very high	9 Å²	9	38.5 Å²	38.5	3%	0.034	19%	0.193	C	C	.	.	H	α-helix	trans	-66	-40	174.9	-75.8	107.6	0	0	0	112.1	H271 L272 W278 W279 L343 I383 A384 Q387 I388	H271-W275 AromaticContact CD2-CD1 3.84Å; H271-W275 AromaticContact CD2-NE1 3.6Å; H271-W275 AromaticContact CE1-CD1 3.32Å; H271-W275 AromaticContact CE1-NE1 3.24Å; H271-W275 PolarHBondContact CE1-NE1 2.94Å; H271-W275 AromaticContact CG-CD1 3.98Å; H271-W275 AromaticContact ND1-CD1 3.66Å; H271-W275 AromaticContact ND1-NE1 3.98Å; H271-W275 AromaticContact NE2-CD1 3.4Å; H271-W275 AromaticContact NE2-NE1 2.9Å; H271-W275 PolarHBondContact NE2-NE1 2.71Å; H271-W275 VanDerWaalsContact O-CD1 3.23Å; H271-W275 PolarHBondContact O-N 3.18Å; L272-W275 PolarHBondContact O-N 2.95Å; W275-W278 PolarHBondContact O-N 3.04Å; W275-W279 WeakPolarHBondContact O-CB 3.26Å; W275-W279 PolarHBondContact O-N 3.4Å; W275-L343 HydrophobicContact CD2-CD1 4.41Å; W275-L343 HydrophobicContact CE3-CD1 3.89Å; W275-L343 HydrophobicContact CE3-CD2 4.05Å; W275-L343 HydrophobicContact CE3-CG 4.33Å; W275-L343 HydrophobicContact CH2-CD1 4.15Å; W275-L343 HydrophobicContact CH2-CD2 4.09Å; W275-L343 HydrophobicContact CH2-CG 4Å; W275-L343 HydrophobicContact CZ3-CD1 3.78Å; W275-L343 HydrophobicContact CZ3-CD2 3.4Å; W275-L343 VanDerWaalsContact CZ3-CD2 3.4Å; W275-L343 HydrophobicContact CZ3-CG 3.72Å; W275-I383 HydrophobicContact CH2-CG2 3.56Å; W275-I383 HydrophobicContact CZ2-CG2 4.44Å; W275-I383 HydrophobicContact CZ3-CG2 3.86Å; W275-A384 VanDerWaalsContact CE3-CA 3.47Å; W275-A384 HydrophobicContact CE3-CB 3.65Å; W275-A384 HydrophobicContact CZ3-CB 4.05Å; W275-Q387 HydrophobicContact CD2-CB 3.84Å; W275-Q387 HydrophobicContact CD2-CG 4.25Å; W275-Q387 HydrophobicContact CE3-CB 4.39Å; W275-Q387 HydrophobicContact CG-CB 4.02Å; W275-Q387 HydrophobicContact CH2-CG 4.11Å; W275-Q387 HydrophobicContact CZ2-CB 4.2Å; W275-Q387 HydrophobicContact CZ2-CG 3.69Å; W275-I388 HydrophobicContact CB-CD1 3.96Å; W275-I388 HydrophobicContact CB-CG1 3.72Å
276	S	94.2	Very high	92.7	Very high	3 Å²	3	35.3 Å²	35.3	2%	0.021	18%	0.178	C	C	.	.	H	α-helix	trans	-66.8	-41.8	178	-54.5	0	0	0	0	111.5	L272 V273 W279 A280 D404	L272-S276 WeakPolarHBondContact CD2-OG 3.48Å; L272-S276 VanDerWaalsContact O-CB 3.26Å; L272-S276 WeakPolarHBondContact O-CB 3.48Å; L272-S276 PolarHBondContact O-N 3.26Å; L272-S276 PolarHBondContact O-OG 2.88Å; V273-S276 PolarHBondContact O-N 3.38Å; S276-W279 WeakPolarHBondContact O-CB 3.34Å; S276-W279 PolarHBondContact O-N 2.94Å; S276-A280 WeakPolarHBondContact O-CB 3.49Å; S276-A280 PolarHBondContact O-N 3.02Å; S276-D404 WeakPolarHBondContact CA-OD2 3.48Å; S276-D404 WeakPolarHBondContact CB-OD1 3.25Å; S276-D404 VanDerWaalsContact CB-OD2 3.28Å; S276-D404 WeakPolarHBondContact CB-OD2 3.18Å; S276-D404 PolarHBondContact OG-OD2 2.94Å
277	L	94.6	Very high	93.5	Very high	75 Å²	75	36.2 Å²	36.2	39%	0.393	18%	0.182	S	C	.	.	H	α-helix	trans	-62.1	-49.2	173.3	-74.5	172.6	0	0	0	111	V273 W279 A280 F281	V273-L277 HydrophobicContact CG1-CD1 3.75Å; V273-L277 HydrophobicContact CG1-CG 4.2Å; V273-L277 WeakPolarHBondContact O-CB 2.92Å; V273-L277 WeakPolarHBondContact O-CG 3.45Å; V273-L277 PolarHBondContact O-N 3.41Å; L277-W279 VanDerWaalsContact C-N 3.29Å; L277-W279 PolarHBondContact O-N 3.33Å; L277-A280 PolarHBondContact O-N 3.34Å; L277-F281 HydrophobicContact CB-CD2 4.41Å; L277-F281 HydrophobicContact CB-CE2 4.44Å; L277-F281 HydrophobicContact CD2-CE2 4.11Å; L277-F281 WeakPolarHBondContact O-CD2 3.47Å; L277-F281 PolarHBondContact O-N 2.67Å
278	W	96.6	Very high	94.1	Very high	1 Å²	1	33.5 Å²	33.5	0%	0.004	17%	0.172	C	C	.	.	H	α-helix	trans	-56.5	-46.4	176.8	-178.7	84.3	0	0	0	111.1	Y274 W275 A280 F281 A282 L343 S347 L380 I381 A384 F447	Y274-W278 PolarHBondContact O-N 3.45Å; W275-W278 PolarHBondContact O-N 3.04Å; W278-A280 PolarHBondContact O-N 3.05Å; W278-F281 PolarHBondContact O-N 3.23Å; W278-A282 HydrophobicContact CD2-CB 4.06Å; W278-A282 HydrophobicContact CE3-CB 4.33Å; W278-A282 HydrophobicContact CH2-CB 3.7Å; W278-A282 HydrophobicContact CZ2-CB 3.4Å; W278-A282 VanDerWaalsContact CZ2-CB 3.4Å; W278-A282 HydrophobicContact CZ3-CB 4.17Å; W278-A282 WeakPolarHBondContact O-CB 3.21Å; W278-A282 PolarHBondContact O-N 2.84Å; W278-L343 HydrophobicContact CB-CD1 3.97Å; W278-L343 HydrophobicContact CD2-CD1 4.41Å; W278-L343 HydrophobicContact CD2-CD2 3.41Å; W278-L343 VanDerWaalsContact CD2-CD2 3.41Å; W278-L343 HydrophobicContact CD2-CG 4.42Å; W278-L343 HydrophobicContact CE3-CD2 3.85Å; W278-L343 HydrophobicContact CG-CD1 3.82Å; W278-L343 HydrophobicContact CG-CD2 3.69Å; W278-L343 HydrophobicContact CG-CG 4.22Å; W278-L343 HydrophobicContact CZ2-CD2 4.22Å; W278-L343 HydrophobicContact CZ3-CD2 4.42Å; W278-S347 PolarHBondContact NE1-OG 3.37Å; W278-L380 HydrophobicContact CH2-CB 3.21Å; W278-L380 HydrophobicContact CH2-CD1 3.97Å; W278-L380 HydrophobicContact CH2-CG 4.27Å; W278-L380 HydrophobicContact CZ2-CB 3.48Å; W278-L380 VanDerWaalsContact CZ2-CB 3.48Å; W278-L380 HydrophobicContact CZ2-CD1 3.28Å; W278-L380 HydrophobicContact CZ2-CG 4.05Å; W278-L380 HydrophobicContact CZ3-CB 4.02Å; W278-I381 HydrophobicContact CZ3-CD1 4.12Å; W278-A384 HydrophobicContact CE3-CB 3.73Å; W278-A384 HydrophobicContact CZ3-CB 3.74Å; W278-F447 HydrophobicContact CB-CE1 4.29Å; W278-F447 HydrophobicContact CB-CE2 3.83Å; W278-F447 HydrophobicContact CB-CZ 3.55Å; W278-F447 AromaticContact CD1-CD2 3.89Å; W278-F447 AromaticContact CD1-CE2 3.63Å; W278-F447 HydrophobicContact CG-CE2 4.12Å; W278-F447 HydrophobicContact CG-CZ 4.21Å
279	W	96.2	Very high	94.7	Very high	11 Å²	11	29.4 Å²	29.4	4%	0.042	14%	0.143	C	C	.	.	H	α-helix	trans	-53.3	-56.7	176	179.4	-30.5	0	0	0	110.4	W275 S276 L277 F281 A282 T283 I381 V385 I388 F401 D404	W275-W279 WeakPolarHBondContact O-CB 3.26Å; W275-W279 PolarHBondContact O-N 3.4Å; S276-W279 WeakPolarHBondContact O-CB 3.34Å; S276-W279 PolarHBondContact O-N 2.94Å; L277-W279 VanDerWaalsContact C-N 3.29Å; L277-W279 PolarHBondContact O-N 3.33Å; W279-F281 PolarHBondContact O-N 3.19Å; W279-A282 PolarHBondContact O-N 3.2Å; W279-T283 WeakPolarHBondContact O-CB 3.42Å; W279-T283 PolarHBondContact O-N 3.05Å; W279-T283 PolarHBondContact O-OG1 3.04Å; W279-I381 HydrophobicContact CB-CD1 4.36Å; W279-I381 HydrophobicContact CD2-CD1 3.83Å; W279-I381 HydrophobicContact CG-CD1 3.71Å; W279-V385 HydrophobicContact CE3-CG2 4.27Å; W279-V385 HydrophobicContact CH2-CG2 3.49Å; W279-V385 VanDerWaalsContact CH2-CG2 3.49Å; W279-V385 HydrophobicContact CZ2-CG2 4.11Å; W279-V385 HydrophobicContact CZ3-CB 4.39Å; W279-V385 HydrophobicContact CZ3-CG2 3.61Å; W279-I388 HydrophobicContact CE3-CD1 3.44Å; W279-I388 VanDerWaalsContact CE3-CD1 3.44Å; W279-I388 HydrophobicContact CZ3-CD1 3.86Å; W279-F401 AromaticContact CH2-CD2 3.35Å; W279-F401 HydrophobicContact CH2-CD2 3.35Å; W279-F401 AromaticContact CH2-CE2 3.74Å; W279-F401 HydrophobicContact CH2-CE2 3.74Å; W279-F401 HydrophobicContact CH2-CG 4.25Å; W279-F401 AromaticContact CZ2-CD2 3.59Å; W279-F401 HydrophobicContact CZ2-CD2 3.59Å; W279-F401 AromaticContact CZ2-CE2 3.56Å; W279-F401 HydrophobicContact CZ2-CE2 3.56Å; W279-F401 HydrophobicContact CZ2-CG 4.43Å; W279-F401 HydrophobicContact CZ2-CZ 4.44Å; W279-D404 HydrophobicContact CD2-CB 4.24Å; W279-D404 HydrophobicContact CG-CB 4.31Å
280	A	97.6	Very high	95.1	Very high	2 Å²	2	29.8 Å²	29.8	2%	0.017	14%	0.14	C	C	.	.	H	α-helix	trans	-59.6	-47.4	-173.7	0	0	0	0	0	111.8	S276 L277 W278 A284 I407 A408 I411	S276-A280 WeakPolarHBondContact O-CB 3.49Å; S276-A280 PolarHBondContact O-N 3.02Å; L277-A280 PolarHBondContact O-N 3.34Å; W278-A280 PolarHBondContact O-N 3.05Å; A280-A284 WeakPolarHBondContact O-CB 3.37Å; A280-A284 PolarHBondContact O-N 3.43Å; A280-A284 VanDerWaalsContact O-N 3.07Å; A280-I407 HydrophobicContact CB-CB 4.16Å; A280-I407 HydrophobicContact CB-CG2 3.81Å; A280-A408 WeakPolarHBondContact O-CA 3.44Å; A280-A408 WeakPolarHBondContact O-CB 3.39Å; A280-I411 HydrophobicContact CB-CD1 4.48Å
281	F	98	Very high	95.6	Very high	81 Å²	81	23.2 Å²	23.2	36%	0.355	11%	0.113	S	C	.	.	H	α-helix	trans	-65.4	-49.5	176.8	-74.5	-71	0	0	0	112	L277 W278 W279 T283 A284 G285 I411 Y439 I443	L277-F281 HydrophobicContact CB-CD2 4.41Å; L277-F281 HydrophobicContact CB-CE2 4.44Å; L277-F281 HydrophobicContact CD2-CE2 4.11Å; L277-F281 WeakPolarHBondContact O-CD2 3.47Å; L277-F281 PolarHBondContact O-N 2.67Å; W278-F281 PolarHBondContact O-N 3.23Å; W279-F281 PolarHBondContact O-N 3.19Å; F281-T283 VanDerWaalsContact C-N 3.3Å; F281-T283 PolarHBondContact O-N 3.32Å; F281-A284 PolarHBondContact O-N 3.42Å; F281-G285 PolarHBondContact O-N 2.85Å; F281-I411 HydrophobicContact CD1-CD1 3.77Å; F281-I411 HydrophobicContact CD1-CG2 4.35Å; F281-I411 HydrophobicContact CE1-CD1 3.76Å; F281-I411 HydrophobicContact CG-CD1 4.29Å; F281-I411 HydrophobicContact CZ-CD1 4.27Å; F281-Y439 VanDerWaalsContact CA-OH 3.27Å; F281-Y439 WeakPolarHBondContact CA-OH 3.41Å; F281-Y439 HydrophobicContact CD1-CE2 4.38Å; F281-Y439 WeakPolarHBondContact CD1-OH 3.36Å; F281-Y439 WeakPolarHBondContact O-CE1 3.22Å; F281-Y439 PolarHBondContact O-OH 3.36Å; F281-I443 HydrophobicContact CB-CD1 3.84Å; F281-I443 HydrophobicContact CB-CG1 4.42Å
282	A	98.2	Very high	96.2	Very high	0 Å²	0	20.7 Å²	20.7	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-62.8	-38.4	-178.4	0	0	0	0	0	112.1	W278 W279 G285 Y286 Y377 F440	W278-A282 HydrophobicContact CD2-CB 4.06Å; W278-A282 HydrophobicContact CE3-CB 4.33Å; W278-A282 HydrophobicContact CH2-CB 3.7Å; W278-A282 HydrophobicContact CZ2-CB 3.4Å; W278-A282 VanDerWaalsContact CZ2-CB 3.4Å; W278-A282 HydrophobicContact CZ3-CB 4.17Å; W278-A282 WeakPolarHBondContact O-CB 3.21Å; W278-A282 PolarHBondContact O-N 2.84Å; W279-A282 PolarHBondContact O-N 3.2Å; A282-G285 PolarHBondContact O-N 3.16Å; A282-Y286 WeakPolarHBondContact O-CB 3.42Å; A282-Y286 PolarHBondContact O-N 2.89Å; A282-Y377 HydrophobicContact CB-CE2 4.29Å; A282-F440 HydrophobicContact CB-CE1 4.24Å
283	T	97.9	Very high	96.6	Very high	14 Å²	14	20.6 Å²	20.6	9%	0.086	10%	0.101	C	C	.	.	H	α-helix	trans	-69.4	-41	178.7	-58.9	0	0	0	0	111.4	W279 F281 G285 Y286 N287 Y377 A408	W279-T283 WeakPolarHBondContact O-CB 3.42Å; W279-T283 PolarHBondContact O-N 3.05Å; W279-T283 PolarHBondContact O-OG1 3.04Å; F281-T283 VanDerWaalsContact C-N 3.3Å; F281-T283 PolarHBondContact O-N 3.32Å; T283-G285 PolarHBondContact O-N 2.83Å; T283-Y286 PolarHBondContact O-N 3.44Å; T283-N287 WeakPolarHBondContact O-CB 3.43Å; T283-N287 PolarHBondContact O-N 3.45Å; T283-N287 PolarHBondContact O-OD1 3.09Å; T283-Y377 PolarHBondContact OG1-OH 3.28Å; T283-A408 HydrophobicContact CG2-CB 4.02Å
284	A	98.5	Very high	96.8	Very high	0 Å²	0	19.9 Å²	19.9	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-58.9	-47.6	173.5	0	0	0	0	0	112	A280 F281 Q288 A408 I411 Q412	A280-A284 WeakPolarHBondContact O-CB 3.37Å; A280-A284 PolarHBondContact O-N 3.43Å; A280-A284 VanDerWaalsContact O-N 3.07Å; F281-A284 PolarHBondContact O-N 3.42Å; A284-Q288 VanDerWaalsContact O-CG 3.22Å; A284-Q288 WeakPolarHBondContact O-CG 3.27Å; A284-Q288 PolarHBondContact O-N 2.89Å; A284-A408 VanDerWaalsContact CB-O 3.25Å; A284-A408 WeakPolarHBondContact CB-O 3.39Å; A284-I411 HydrophobicContact CB-CB 3.83Å; A284-I411 HydrophobicContact CB-CG2 3.65Å; A284-Q412 HydrophobicContact CB-CB 4.12Å
285	G	98.3	Very high	97.1	Very high	0 Å²	0	16.9 Å²	16.9	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-66.2	-39.2	176.9	0	0	0	0	0	113.1	F281 A282 T283 Q288 I289	F281-G285 PolarHBondContact O-N 2.85Å; A282-G285 PolarHBondContact O-N 3.16Å; T283-G285 PolarHBondContact O-N 2.83Å; G285-Q288 WeakPolarHBondContact O-CB 3.4Å; G285-Q288 PolarHBondContact O-N 3.02Å; G285-I289 WeakPolarHBondContact O-CD1 3.12Å; G285-I289 WeakPolarHBondContact O-CG1 3.46Å; G285-I289 PolarHBondContact O-N 3.01Å; G285-I289 VanDerWaalsContact O-N 3.16Å
286	Y	98.4	Very high	97.3	Very high	17 Å²	17	16.4 Å²	16.4	7%	0.067	8%	0.082	C	C	.	.	H	α-helix	trans	-65.9	-44.4	178.4	-179.5	-111.5	0	0	0	112.2	A282 T283 Q288 I289 L290 V373 K374 Y377	A282-Y286 WeakPolarHBondContact O-CB 3.42Å; A282-Y286 PolarHBondContact O-N 2.89Å; T283-Y286 PolarHBondContact O-N 3.44Å; Y286-Q288 PolarHBondContact O-N 3.35Å; Y286-I289 WeakPolarHBondContact O-CB 3.09Å; Y286-I289 PolarHBondContact O-N 3.42Å; Y286-I289 VanDerWaalsContact O-N 3.13Å; Y286-L290 HydrophobicContact CD1-CD1 3.94Å; Y286-L290 HydrophobicContact CD1-CG 4.28Å; Y286-L290 HydrophobicContact CE1-CD1 3.36Å; Y286-L290 HydrophobicContact CE1-CD2 4.36Å; Y286-L290 HydrophobicContact CE1-CG 3.87Å; Y286-L290 HydrophobicContact CE2-CD2 4.15Å; Y286-L290 HydrophobicContact CE2-CG 4.2Å; Y286-L290 PolarHBondContact O-N 3.43Å; Y286-V373 HydrophobicContact CD2-CG1 4.27Å; Y286-V373 HydrophobicContact CE2-CG1 4.38Å; Y286-K374 WeakPolarHBondContact OH-CG 3.47Å; Y286-Y377 AromaticContact CD1-CD1 3.49Å; Y286-Y377 HydrophobicContact CD1-CD1 3.49Å; Y286-Y377 VanDerWaalsContact CD1-CD1 3.49Å; Y286-Y377 HydrophobicContact CD1-CD2 4.28Å; Y286-Y377 AromaticContact CD1-CE1 3.26Å; Y286-Y377 HydrophobicContact CD1-CE1 3.26Å; Y286-Y377 HydrophobicContact CD1-CE2 4.1Å; Y286-Y377 HydrophobicContact CD1-CG 4.01Å; Y286-Y377 AromaticContact CD1-CZ 3.59Å; Y286-Y377 AromaticContact CD2-CD1 3.81Å; Y286-Y377 HydrophobicContact CD2-CD1 3.81Å; Y286-Y377 HydrophobicContact CD2-CD2 4.13Å; Y286-Y377 HydrophobicContact CD2-CE1 4.41Å; Y286-Y377 AromaticContact CD2-CG 3.65Å; Y286-Y377 HydrophobicContact CD2-CG 3.65Å; Y286-Y377 AromaticContact CE1-CD1 3.5Å; Y286-Y377 HydrophobicContact CE1-CD1 3.5Å; Y286-Y377 VanDerWaalsContact CE1-CD1 3.5Å; Y286-Y377 AromaticContact CE1-CE1 3.45Å; Y286-Y377 HydrophobicContact CE1-CE1 3.45Å; Y286-Y377 VanDerWaalsContact CE1-CE1 3.45Å; Y286-Y377 HydrophobicContact CE1-CG 4.32Å; Y286-Y377 AromaticContact CE2-CD1 3.86Å; Y286-Y377 HydrophobicContact CE2-CD1 3.86Å; Y286-Y377 HydrophobicContact CE2-CG 4.04Å; Y286-Y377 AromaticContact CG-CD1 3.64Å; Y286-Y377 HydrophobicContact CG-CD1 3.64Å; Y286-Y377 AromaticContact CG-CD2 3.79Å; Y286-Y377 HydrophobicContact CG-CD2 3.79Å; Y286-Y377 AromaticContact CG-CE1 3.78Å; Y286-Y377 HydrophobicContact CG-CE1 3.78Å; Y286-Y377 AromaticContact CG-CE2 3.92Å; Y286-Y377 HydrophobicContact CG-CE2 3.92Å; Y286-Y377 AromaticContact CG-CG 3.64Å; Y286-Y377 HydrophobicContact CG-CG 3.64Å; Y286-Y377 AromaticContact CG-CZ 3.91Å; Y286-Y377 AromaticContact CZ-CD1 3.7Å
287	N	97.6	Very high	97.4	Very high	25 Å²	25	16.4 Å²	16.4	13%	0.134	8%	0.081	C	C	.	.	H	α-helix	trans	-59.1	-33.8	175.8	-72.1	-7.1	0	0	0	112.1	W60 T283 L290 N291 Q412	W60-N287 HydrophobicContact CH2-CB 4.36Å; T283-N287 WeakPolarHBondContact O-CB 3.43Å; T283-N287 PolarHBondContact O-N 3.45Å; T283-N287 PolarHBondContact O-OD1 3.09Å; N287-L290 PolarHBondContact O-N 2.91Å; N287-N291 WeakPolarHBondContact O-CB 3.32Å; N287-N291 PolarHBondContact O-N 3.38Å; N287-Q412 HydrophobicContact CB-CG 4.4Å; N287-Q412 VanDerWaalsContact CB-OE1 3.25Å; N287-Q412 PolarHBondContact ND2-OE1 3.32Å
288	Q	97.9	Very high	97.5	Very high	0 Å²	0	14 Å²	14	0%	0	7%	0.068	C	C	.	.	H	α-helix	trans	-69.8	-42.5	177.3	-70.2	-98.3	-4.2	0	0	111.6	A284 G285 Y286 L290 N291 Y292 Q412 M415 T416 Y436	A284-Q288 VanDerWaalsContact O-CG 3.22Å; A284-Q288 WeakPolarHBondContact O-CG 3.27Å; A284-Q288 PolarHBondContact O-N 2.89Å; G285-Q288 WeakPolarHBondContact O-CB 3.4Å; G285-Q288 PolarHBondContact O-N 3.02Å; Y286-Q288 PolarHBondContact O-N 3.35Å; Q288-L290 VanDerWaalsContact C-N 3.33Å; Q288-L290 PolarHBondContact O-N 2.83Å; Q288-N291 PolarHBondContact O-N 3.36Å; Q288-Y292 WeakPolarHBondContact O-CD2 3.3Å; Q288-Y292 PolarHBondContact O-N 3.3Å; Q288-Q412 HydrophobicContact CG-CG 3.94Å; Q288-Q412 PolarHBondContact NE2-O 2.86Å; Q288-M415 HydrophobicContact CB-CE 3.77Å; Q288-M415 HydrophobicContact CG-CE 3.29Å; Q288-T416 PolarHBondContact NE2-OG1 2.97Å; Q288-Y436 HydrophobicContact CB-CD1 4.28Å; Q288-Y436 HydrophobicContact CB-CE1 3.84Å; Q288-Y436 HydrophobicContact CB-CE2 4.27Å; Q288-Y436 HydrophobicContact CG-CE1 4.4Å; Q288-Y436 PolarHBondContact OE1-OH 3.35Å
289	I	98.2	Very high	97.4	Very high	0 Å²	0	19 Å²	19	0%	0	9%	0.091	C	C	.	.	H	α-helix	trans	-59.3	-48.9	173.2	-61.8	158.6	0	0	0	109.5	G285 Y286 N291 Y292 V293 L354 V373 F433 Y436 F440	G285-I289 WeakPolarHBondContact O-CD1 3.12Å; G285-I289 WeakPolarHBondContact O-CG1 3.46Å; G285-I289 PolarHBondContact O-N 3.01Å; G285-I289 VanDerWaalsContact O-N 3.16Å; Y286-I289 WeakPolarHBondContact O-CB 3.09Å; Y286-I289 PolarHBondContact O-N 3.42Å; Y286-I289 VanDerWaalsContact O-N 3.13Å; I289-N291 VanDerWaalsContact C-N 3.34Å; I289-N291 PolarHBondContact O-N 3.46Å; I289-Y292 PolarHBondContact O-N 2.74Å; I289-V293 WeakPolarHBondContact O-CB 3.39Å; I289-V293 PolarHBondContact O-N 2.96Å; I289-L354 HydrophobicContact CD1-CD1 3.66Å; I289-L354 HydrophobicContact CD1-CD2 3.79Å; I289-L354 HydrophobicContact CD1-CG 4.26Å; I289-L354 HydrophobicContact CG1-CD1 4.29Å; I289-L354 HydrophobicContact CG1-CD2 3.83Å; I289-L354 HydrophobicContact CG2-CD2 4.23Å; I289-V373 HydrophobicContact CD1-CG1 3.94Å; I289-V373 HydrophobicContact CG2-CG1 4.34Å; I289-F433 HydrophobicContact CG2-CE1 4.18Å; I289-F433 HydrophobicContact CG2-CZ 4.44Å; I289-Y436 HydrophobicContact CG1-CD2 4.44Å; I289-F440 HydrophobicContact CD1-CD2 4.33Å; I289-F440 HydrophobicContact CD1-CE2 3.68Å; I289-F440 HydrophobicContact CD1-CZ 4.44Å
290	L	96.5	Very high	97.3	Very high	60 Å²	60	20.4 Å²	20.4	31%	0.314	10%	0.098	S	C	.	.	H	α-helix	trans	-58.7	-43.2	179.2	-70.4	-173.1	0	0	0	112.9	Y286 N287 Q288 Y292 Y370	Y286-L290 HydrophobicContact CD1-CD1 3.94Å; Y286-L290 HydrophobicContact CD1-CG 4.28Å; Y286-L290 HydrophobicContact CE1-CD1 3.36Å; Y286-L290 HydrophobicContact CE1-CD2 4.36Å; Y286-L290 HydrophobicContact CE1-CG 3.87Å; Y286-L290 HydrophobicContact CE2-CD2 4.15Å; Y286-L290 HydrophobicContact CE2-CG 4.2Å; Y286-L290 PolarHBondContact O-N 3.43Å; N287-L290 PolarHBondContact O-N 2.91Å; Q288-L290 VanDerWaalsContact C-N 3.33Å; Q288-L290 PolarHBondContact O-N 2.83Å; L290-Y292 VanDerWaalsContact C-N 3.32Å; L290-Y292 PolarHBondContact O-N 3.03Å; L290-Y370 HydrophobicContact CD2-CE2 3.97Å
291	N	97	Very high	97.2	Very high	24 Å²	24	20.7 Å²	20.7	13%	0.128	10%	0.1	C	C	.	.	H	α-helix	trans	-67	-32.1	-177.1	-159	43.6	0	0	0	113	L57 W60 N287 Q288 I289	L57-N291 PolarHBondContact O-ND2 2.68Å; W60-N291 HydrophobicContact CE3-CB 4.19Å; W60-N291 VanDerWaalsContact CE3-OD1 3.3Å; W60-N291 HydrophobicContact CZ3-CB 3.87Å; N287-N291 WeakPolarHBondContact O-CB 3.32Å; N287-N291 PolarHBondContact O-N 3.38Å; Q288-N291 PolarHBondContact O-N 3.36Å; I289-N291 VanDerWaalsContact C-N 3.34Å; I289-N291 PolarHBondContact O-N 3.46Å
292	Y	97.8	Very high	97	Very high	0 Å²	0	19.3 Å²	19.3	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-114.7	-2.9	-171.8	-58.6	-71.5	0	0	0	114.7	T53 L57 Q288 I289 L290 Q294 V295 L296 V420 Y436	T53-Y292 HydrophobicContact CG2-CD1 4.21Å; T53-Y292 HydrophobicContact CG2-CE1 4.39Å; L57-Y292 HydrophobicContact CB-CD1 4.46Å; L57-Y292 HydrophobicContact CB-CE1 3.72Å; L57-Y292 HydrophobicContact CD1-CD1 3.83Å; L57-Y292 HydrophobicContact CD1-CE1 3.91Å; Q288-Y292 WeakPolarHBondContact O-CD2 3.3Å; Q288-Y292 PolarHBondContact O-N 3.3Å; I289-Y292 PolarHBondContact O-N 2.74Å; L290-Y292 VanDerWaalsContact C-N 3.32Å; L290-Y292 PolarHBondContact O-N 3.03Å; Y292-Q294 PolarHBondContact O-N 2.87Å; Y292-V295 WeakPolarHBondContact O-CB 3.5Å; Y292-V295 PolarHBondContact O-N 2.9Å; Y292-L296 PolarHBondContact O-N 3.43Å; Y292-V420 HydrophobicContact CE1-CG1 3.76Å; Y292-V420 HydrophobicContact CE2-CG1 4.46Å; Y292-V420 HydrophobicContact CE2-CG2 3.94Å; Y292-V420 WeakPolarHBondContact OH-CG1 3.49Å; Y292-Y436 HydrophobicContact CD2-CE2 4.33Å; Y292-Y436 VanDerWaalsContact CD2-OH 3.24Å; Y292-Y436 WeakPolarHBondContact CD2-OH 3.38Å
293	V	97.6	Very high	96.6	Very high	3 Å²	3	20 Å²	20	2%	0.018	10%	0.104	C	C	.	.	H	α-helix	trans	-63.6	-38.5	-177.4	69.9	0	0	0	0	113	I289 V295 L296 W297 M357 Y370 F433	I289-V293 WeakPolarHBondContact O-CB 3.39Å; I289-V293 PolarHBondContact O-N 2.96Å; V293-V295 VanDerWaalsContact C-N 3.31Å; V293-V295 PolarHBondContact O-N 3.2Å; V293-L296 WeakPolarHBondContact O-CB 3.43Å; V293-L296 PolarHBondContact O-N 3.46Å; V293-W297 HydrophobicContact CG1-CH2 4.31Å; V293-W297 HydrophobicContact CG1-CZ2 4.38Å; V293-W297 HydrophobicContact CG2-CD2 4.21Å; V293-W297 VanDerWaalsContact CG2-CE2 3.5Å; V293-W297 HydrophobicContact CG2-CH2 4.29Å; V293-W297 HydrophobicContact CG2-CZ2 3.55Å; V293-W297 VanDerWaalsContact O-CG 3.3Å; V293-W297 PolarHBondContact O-N 3.29Å; V293-M357 HydrophobicContact CG2-CE 4.02Å; V293-Y370 HydrophobicContact CB-CD2 4.49Å; V293-Y370 HydrophobicContact CG1-CD2 4.43Å; V293-Y370 HydrophobicContact CG1-CE2 4.09Å; V293-Y370 HydrophobicContact CG2-CD2 3.85Å; V293-Y370 HydrophobicContact CG2-CE2 4.35Å; V293-Y370 HydrophobicContact CG2-CG 4.3Å; V293-F433 HydrophobicContact CB-CZ 4.12Å; V293-F433 HydrophobicContact CG2-CZ 4.35Å
294	Q	96.9	Very high	96.1	Very high	25 Å²	25	25 Å²	25	12%	0.117	13%	0.126	C	C	.	.	H	α-helix	trans	-67.8	-33.3	177	-70.3	-173	44.1	0	0	112	E33 A34 I37 Y292 L296 W297 E298	E33-Q294 PolarHBondContact O-NE2 2.87Å; A34-Q294 PolarHBondContact O-OE1 3.32Å; I37-Q294 HydrophobicContact CB-CB 3.85Å; I37-Q294 HydrophobicContact CG1-CB 3.42Å; I37-Q294 VanDerWaalsContact CG1-CB 3.42Å; Y292-Q294 PolarHBondContact O-N 2.87Å; Q294-L296 VanDerWaalsContact C-N 3.33Å; Q294-W297 HydrophobicContact CB-CE3 4.45Å; Q294-W297 HydrophobicContact CG-CE3 3.95Å; Q294-W297 HydrophobicContact CG-CZ3 4Å; Q294-W297 PolarHBondContact O-N 2.97Å; Q294-E298 WeakPolarHBondContact O-CB 3.35Å; Q294-E298 PolarHBondContact O-N 3.33Å
295	V	97.2	Very high	95.5	Very high	4 Å²	4	31.6 Å²	31.6	2%	0.024	16%	0.162	C	C	.	.	H	α-helix	trans	-64	-41.6	172.8	-178.1	0	0	0	0	110.6	I37 T53 L57 Y292 V293 W297 E298 H299 V429	I37-V295 HydrophobicContact CD1-CG2 3.82Å; I37-V295 HydrophobicContact CG1-CG2 3.92Å; I37-V295 HydrophobicContact CG2-CG2 4.34Å; T53-V295 HydrophobicContact CG2-CG1 4.4Å; T53-V295 WeakPolarHBondContact OG1-CG1 3.36Å; L57-V295 HydrophobicContact CD1-CG2 3.52Å; Y292-V295 WeakPolarHBondContact O-CB 3.5Å; Y292-V295 PolarHBondContact O-N 2.9Å; V293-V295 VanDerWaalsContact C-N 3.31Å; V293-V295 PolarHBondContact O-N 3.2Å; V295-W297 VanDerWaalsContact C-N 3.33Å; V295-E298 PolarHBondContact O-N 3.48Å; V295-H299 WeakPolarHBondContact O-CB 3.34Å; V295-H299 PolarHBondContact O-N 2.89Å; V295-V429 HydrophobicContact CB-CG2 4.08Å; V295-V429 HydrophobicContact CG1-CB 3.93Å; V295-V429 HydrophobicContact CG1-CG1 4.16Å; V295-V429 HydrophobicContact CG1-CG2 3.92Å
296	L	97.1	Very high	94.9	Very high	0 Å²	0	33.9 Å²	33.9	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-62.4	-43.6	174.4	-177.6	69.4	0	0	0	110.8	Y292 V293 Q294 H299 K300 M357 V429 F433	Y292-L296 PolarHBondContact O-N 3.43Å; V293-L296 WeakPolarHBondContact O-CB 3.43Å; V293-L296 PolarHBondContact O-N 3.46Å; Q294-L296 VanDerWaalsContact C-N 3.33Å; L296-H299 PolarHBondContact O-N 2.91Å; L296-K300 HydrophobicContact CD1-CG 4.3Å; L296-K300 HydrophobicContact CG-CG 4.34Å; L296-K300 WeakPolarHBondContact O-CG 3.37Å; L296-K300 PolarHBondContact O-N 3.33Å; L296-M357 HydrophobicContact CD2-CB 4.18Å; L296-M357 HydrophobicContact CD2-CE 4.03Å; L296-V429 HydrophobicContact CB-CG2 3.94Å; L296-V429 HydrophobicContact CD1-CG1 4.34Å; L296-V429 HydrophobicContact CD1-CG2 4.44Å; L296-F433 HydrophobicContact CB-CD2 4.23Å; L296-F433 HydrophobicContact CB-CE2 3.81Å; L296-F433 HydrophobicContact CB-CZ 4.16Å; L296-F433 HydrophobicContact CD1-CD2 4.36Å; L296-F433 HydrophobicContact CD2-CD1 3.71Å; L296-F433 HydrophobicContact CD2-CD2 3.95Å; L296-F433 HydrophobicContact CD2-CE1 3.74Å; L296-F433 HydrophobicContact CD2-CE2 3.99Å; L296-F433 HydrophobicContact CD2-CG 3.83Å; L296-F433 HydrophobicContact CD2-CZ 3.9Å; L296-F433 HydrophobicContact CG-CD2 4.41Å; L296-F433 HydrophobicContact CG-CE2 4.39Å
297	W	97.1	Very high	94.4	Very high	3 Å²	3	37.2 Å²	37.2	1%	0.011	20%	0.203	C	C	.	.	H	α-helix	trans	-61.6	-46.9	177.9	-65.8	-17.9	0	0	0	112.2	V293 Q294 V295 H299 K300 A301 N310 V313 I363 Y367 Y370	V293-W297 HydrophobicContact CG1-CH2 4.31Å; V293-W297 HydrophobicContact CG1-CZ2 4.38Å; V293-W297 HydrophobicContact CG2-CD2 4.21Å; V293-W297 VanDerWaalsContact CG2-CE2 3.5Å; V293-W297 HydrophobicContact CG2-CH2 4.29Å; V293-W297 HydrophobicContact CG2-CZ2 3.55Å; V293-W297 VanDerWaalsContact O-CG 3.3Å; V293-W297 PolarHBondContact O-N 3.29Å; Q294-W297 HydrophobicContact CB-CE3 4.45Å; Q294-W297 HydrophobicContact CG-CE3 3.95Å; Q294-W297 HydrophobicContact CG-CZ3 4Å; Q294-W297 PolarHBondContact O-N 2.97Å; V295-W297 VanDerWaalsContact C-N 3.33Å; W297-H299 VanDerWaalsContact C-N 3.28Å; W297-H299 PolarHBondContact O-N 2.83Å; W297-K300 PolarHBondContact O-N 3.07Å; W297-K300 VanDerWaalsContact O-N 3.1Å; W297-A301 PolarHBondContact O-N 2.81Å; W297-N310 HydrophobicContact CE3-CB 4.18Å; W297-N310 HydrophobicContact CZ3-CB 4Å; W297-V313 HydrophobicContact CH2-CG1 3.99Å; W297-V313 HydrophobicContact CZ2-CG1 4.07Å; W297-I363 HydrophobicContact CB-CD1 3.65Å; W297-I363 HydrophobicContact CG-CD1 3.68Å; W297-Y367 HydrophobicContact CD2-CD1 4.08Å; W297-Y367 AromaticContact CD2-CE1 3.61Å; W297-Y367 HydrophobicContact CD2-CE1 3.61Å; W297-Y367 AromaticContact CE2-CD1 3.59Å; W297-Y367 AromaticContact CE2-CE1 3.64Å; W297-Y367 AromaticContact CE3-CE1 4Å; W297-Y367 HydrophobicContact CE3-CE1 4Å; W297-Y367 HydrophobicContact CG-CD1 4.44Å; W297-Y367 AromaticContact CG-CE1 3.94Å; W297-Y367 HydrophobicContact CG-CE1 3.94Å; W297-Y367 HydrophobicContact CH2-CD1 4.49Å; W297-Y367 HydrophobicContact CH2-CE1 4.44Å; W297-Y367 AromaticContact CZ2-CD1 3.84Å; W297-Y367 HydrophobicContact CZ2-CD1 3.84Å; W297-Y367 HydrophobicContact CZ2-CE1 4.08Å; W297-Y367 HydrophobicContact CZ3-CE1 4.39Å; W297-Y367 AromaticContact NE1-CD1 3.71Å; W297-Y367 AromaticContact NE1-CE1 3.96Å; W297-Y370 AromaticContact CH2-CD1 3.88Å; W297-Y370 HydrophobicContact CH2-CD1 3.88Å; W297-Y370 AromaticContact CH2-CE1 3.92Å; W297-Y370 HydrophobicContact CH2-CE1 3.92Å; W297-Y370 HydrophobicContact CH2-CG 4.34Å; W297-Y370 AromaticContact CZ2-CD1 3.65Å; W297-Y370 HydrophobicContact CZ2-CD1 3.65Å; W297-Y370 HydrophobicContact CZ2-CD2 4.37Å; W297-Y370 HydrophobicContact CZ2-CE1 4.15Å; W297-Y370 AromaticContact CZ2-CG 3.74Å; W297-Y370 HydrophobicContact CZ2-CG 3.74Å
298	E	96.1	Very high	94.2	Very high	24 Å²	24	36.6 Å²	36.6	11%	0.112	20%	0.2	C	C	.	.	H	α-helix	trans	-60.4	-39	176.2	-167.8	64.5	-158.5	0	0	111.6	I37 Q294 V295 K300 A301 P302 S303	I37-E298 HydrophobicContact CG2-CB 3.91Å; I37-E298 HydrophobicContact CG2-CG 4.2Å; Q294-E298 WeakPolarHBondContact O-CB 3.35Å; Q294-E298 PolarHBondContact O-N 3.33Å; V295-E298 PolarHBondContact O-N 3.48Å; E298-K300 PolarHBondContact O-N 3.34Å; E298-A301 CarbonylContact O-C 3.46Å; E298-P302 VanDerWaalsContact O-CA 3.27Å; E298-P302 WeakPolarHBondContact O-CA 3.24Å; E298-P302 WeakPolarHBondContact O-CD 3.37Å; E298-P302 VanDerWaalsContact O-N 3.14Å; E298-S303 WeakPolarHBondContact OE1-CB 3.33Å; E298-S303 PolarHBondContact OE1-N 3.02Å; E298-S303 PolarHBondContact OE1-OG 3Å; E298-S303 VanDerWaalsContact OE2-CB 3.25Å; E298-S303 WeakPolarHBondContact OE2-CB 3.44Å; E298-S303 PolarHBondContact OE2-N 3.42Å; E298-S303 PolarHBondContact OE2-OG 2.79Å
299	H	95.4	Very high	94.1	Very high	105 Å²	105	40.4 Å²	40.4	49%	0.486	22%	0.215	S	C	.	.	H	α-helix	trans	-65.8	-35.1	175.3	178.9	70.3	0	0	0	113.2	V295 L296 W297 V429 T430	V295-H299 WeakPolarHBondContact O-CB 3.34Å; V295-H299 PolarHBondContact O-N 2.89Å; L296-H299 PolarHBondContact O-N 2.91Å; W297-H299 VanDerWaalsContact C-N 3.28Å; W297-H299 PolarHBondContact O-N 2.83Å; H299-V429 HydrophobicContact CB-CG1 4.01Å; H299-T430 PolarHBondContact CD2-OG1 2.82Å; H299-T430 PolarHBondContact NE2-OG1 3.47Å
300	K	94.6	Very high	94	Very high	41 Å²	41	40.5 Å²	40.5	18%	0.178	22%	0.215	C	C	.	.	H	α-helix	trans	-85.6	-32.9	-177.1	-64	-72.5	-176.7	175.3	0	112.7	L296 W297 E298 N358 S360	L296-K300 HydrophobicContact CD1-CG 4.3Å; L296-K300 HydrophobicContact CG-CG 4.34Å; L296-K300 WeakPolarHBondContact O-CG 3.37Å; L296-K300 PolarHBondContact O-N 3.33Å; W297-K300 PolarHBondContact O-N 3.07Å; W297-K300 VanDerWaalsContact O-N 3.1Å; E298-K300 PolarHBondContact O-N 3.34Å; K300-N358 PolarHBondContact NZ-O 3.03Å; K300-S360 WeakPolarHBondContact CE-O 3.5Å; K300-S360 PolarHBondContact NZ-O 3.35Å
301	A	95.5	Very high	93.9	Very high	8 Å²	8	37.6 Å²	37.6	7%	0.066	20%	0.2	C	C	.	.	S	Bend	trans	-145.7	86.8	178.5	0	0	0	0	0	108.8	W297 E298 S303 I363	W297-A301 PolarHBondContact O-N 2.81Å; E298-A301 CarbonylContact O-C 3.46Å; A301-S303 PolarHBondContact O-N 3.49Å; A301-I363 HydrophobicContact CB-CB 3.8Å; A301-I363 HydrophobicContact CB-CD1 4.41Å; A301-I363 HydrophobicContact CB-CG1 4.04Å; A301-I363 HydrophobicContact CB-CG2 4.05Å
302	P	93.6	Very high	93.9	Very high	52 Å²	52	38 Å²	38	34%	0.338	21%	0.207	S	C	.	.			trans	-53.6	129.6	179.2	-27	35	0	0	0	111.3	E298 Q304 D305 S306	E298-P302 VanDerWaalsContact O-CA 3.27Å; E298-P302 WeakPolarHBondContact O-CA 3.24Å; E298-P302 WeakPolarHBondContact O-CD 3.37Å; E298-P302 VanDerWaalsContact O-N 3.14Å; P302-Q304 PolarHBondContact O-N 3.33Å; P302-Q304 VanDerWaalsContact O-N 3.13Å; P302-D305 PolarHBondContact O-N 3.2Å; P302-S306 WeakPolarHBondContact O-CB 3.25Å; P302-S306 PolarHBondContact O-N 2.81Å
303	S	90.4	Very high	93.9	Very high	14 Å²	14	38.5 Å²	38.5	10%	0.098	21%	0.21	C	C	.	.	T	Hydrogen-bonded Turn	trans	-62.9	-20.7	-174.2	59.4	0	0	0	0	113.9	E298 A301	E298-S303 WeakPolarHBondContact OE1-CB 3.33Å; E298-S303 PolarHBondContact OE1-N 3.02Å; E298-S303 PolarHBondContact OE1-OG 3Å; E298-S303 VanDerWaalsContact OE2-CB 3.25Å; E298-S303 WeakPolarHBondContact OE2-CB 3.44Å; E298-S303 PolarHBondContact OE2-N 3.42Å; E298-S303 PolarHBondContact OE2-OG 2.79Å; A301-S303 PolarHBondContact O-N 3.49Å
304	Q	85.9	Confident	93.8	Very high	120 Å²	120	38.8 Å²	38.8	56%	0.561	21%	0.211	S	C	*	.	T	Hydrogen-bonded Turn	trans	-75.5	-29.7	176.9	-59.8	-179.3	13.9	0	0	112.6	S41 P302	S41-Q304 PolarHBondContact O-NE2 2.82Å; P302-Q304 PolarHBondContact O-N 3.33Å; P302-Q304 VanDerWaalsContact O-N 3.13Å
305	D	85.7	Confident	93.8	Very high	139 Å²	139	38 Å²	38	74%	0.743	21%	0.208	S	C	*	.	T	Hydrogen-bonded Turn	trans	-112.1	-9.4	-172.4	-62.6	-37.2	0	0	0	113	P302	P302-D305 PolarHBondContact O-N 3.2Å
306	S	86.7	Confident	93.8	Very high	48 Å²	48	42.4 Å²	42.4	34%	0.336	23%	0.231	S	C	.	.	S	Bend	trans	-133.1	144.8	-170	-60.7	0	0	0	0	112.6	P302 I308	P302-S306 WeakPolarHBondContact O-CB 3.25Å; P302-S306 PolarHBondContact O-N 2.81Å; S306-I308 PolarHBondContact O-N 3.31Å
307	S	88.3	Confident	93.8	Very high	87 Å²	87	42.4 Å²	42.4	61%	0.608	23%	0.231	S	C	*	.			trans	-72	108.9	168.3	61.6	0	0	0	0	110.2	Y309	S307-Y309 WeakPolarHBondContact O-CE2 3.32Å
308	I	92.6	Very high	93.6	Very high	12 Å²	12	42.7 Å²	42.7	6%	0.062	23%	0.233	C	C	.	.			trans	-95.9	143.9	179.8	58.7	163.6	0	0	0	112.2	F35 P38 Q160 Y170 S306	F35-I308 HydrophobicContact CD1-CD1 3.77Å; F35-I308 HydrophobicContact CE1-CD1 3.68Å; F35-I308 HydrophobicContact CE1-CG1 4.14Å; P38-I308 HydrophobicContact CB-CD1 4.06Å; P38-I308 HydrophobicContact CG-CD1 3.65Å; Q160-I308 PolarHBondContact NE2-O 2.94Å; Q160-I308 VanDerWaalsContact NE2-O 3.12Å; Y170-I308 WeakPolarHBondContact OH-CD1 3.38Å; S306-I308 PolarHBondContact O-N 3.31Å
309	Y	95.5	Very high	93.4	Very high	80 Å²	80	48 Å²	48	31%	0.314	26%	0.256	S	S	.	.			trans	-121.8	29	-176.6	-61.1	-81.3	0	0	0	112.8	Q160 S307 G311 A312 V313 W364 Y367	Q160-Y309 VanDerWaalsContact OE1-CA 3.24Å; Q160-Y309 PolarHBondContact OE1-O 3.18Å; S307-Y309 WeakPolarHBondContact O-CE2 3.32Å; Y309-G311 VanDerWaalsContact C-N 3.29Å; Y309-G311 PolarHBondContact O-N 2.97Å; Y309-A312 PolarHBondContact O-N 3.07Å; Y309-A312 VanDerWaalsContact O-N 3.15Å; Y309-V313 VanDerWaalsContact O-CG2 3.27Å; Y309-V313 WeakPolarHBondContact O-CG2 3.42Å; Y309-V313 PolarHBondContact O-N 3.34Å; Y309-W364 AromaticContact CD2-CH2 3.62Å; Y309-W364 HydrophobicContact CD2-CH2 3.62Å; Y309-W364 AromaticContact CD2-CZ2 3.96Å; Y309-W364 HydrophobicContact CD2-CZ2 3.96Å; Y309-W364 HydrophobicContact CD2-CZ3 4.4Å; Y309-W364 AromaticContact CE2-CH2 3.73Å; Y309-W364 HydrophobicContact CE2-CH2 3.73Å; Y309-W364 AromaticContact CE2-CZ2 3.78Å; Y309-W364 HydrophobicContact CE2-CZ2 3.78Å; Y309-W364 HydrophobicContact CG-CH2 4.33Å; Y309-Y367 PolarHBondContact N-OH 3.37Å
310	N	95.9	Very high	93.3	Very high	1 Å²	1	43.9 Å²	43.9	1%	0.005	24%	0.242	C	C	.	.	H	α-helix	trans	-55.3	-42.7	-173.7	-63.1	-1.6	0	0	0	112.3	A34 F35 W297 V313 E314 Y367	A34-N310 HydrophobicContact CB-CB 4.17Å; A34-N310 WeakPolarHBondContact O-CB 3.32Å; A34-N310 PolarHBondContact O-ND2 3.18Å; A34-N310 VanDerWaalsContact O-ND2 3.13Å; F35-N310 HydrophobicContact CE1-CB 4.36Å; W297-N310 HydrophobicContact CE3-CB 4.18Å; W297-N310 HydrophobicContact CZ3-CB 4Å; N310-V313 PolarHBondContact O-N 3.03Å; N310-E314 VanDerWaalsContact O-CB 3.3Å; N310-E314 WeakPolarHBondContact O-CB 3.45Å; N310-E314 PolarHBondContact O-N 3.36Å; N310-Y367 PolarHBondContact OD1-OH 2.96Å
311	G	96.1	Very high	93.4	Very high	0 Å²	0	42 Å²	42	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-65.5	-41.8	179.2	0	0	0	0	0	112.9	S156 Y309 E314 A315	S156-G311 VanDerWaalsContact CB-O 3.31Å; S156-G311 WeakPolarHBondContact CB-O 3.3Å; S156-G311 CarbonylContact O-C 3.56Å; Y309-G311 VanDerWaalsContact C-N 3.29Å; Y309-G311 PolarHBondContact O-N 2.97Å; G311-E314 PolarHBondContact O-N 3.38Å; G311-A315 WeakPolarHBondContact O-CB 3.48Å; G311-A315 PolarHBondContact O-N 2.95Å
312	A	96.4	Very high	93.2	Very high	32 Å²	32	43.5 Å²	43.5	26%	0.264	25%	0.247	S	C	.	.	H	α-helix	trans	-64.4	-43.5	174.3	0	0	0	0	0	111.6	Q160 Y309 A315 I316	Q160-A312 HydrophobicContact CB-CB 4.48Å; Q160-A312 HydrophobicContact CG-CB 3.88Å; Q160-A312 VanDerWaalsContact OE1-N 3.16Å; Y309-A312 PolarHBondContact O-N 3.07Å; Y309-A312 VanDerWaalsContact O-N 3.15Å; A312-A315 PolarHBondContact O-N 2.85Å; A312-I316 VanDerWaalsContact O-CG1 3.25Å; A312-I316 WeakPolarHBondContact O-CG1 3.46Å; A312-I316 PolarHBondContact O-N 3.4Å
313	V	97.5	Very high	93.2	Very high	10 Å²	10	45.8 Å²	45.8	6%	0.061	26%	0.256	C	S	.	.	H	α-helix	trans	-62.2	-45.8	178.9	172.4	0	0	0	0	110.2	W297 Y309 N310 A315 I316 A317 Y367 Y370 L371	W297-V313 HydrophobicContact CH2-CG1 3.99Å; W297-V313 HydrophobicContact CZ2-CG1 4.07Å; Y309-V313 VanDerWaalsContact O-CG2 3.27Å; Y309-V313 WeakPolarHBondContact O-CG2 3.42Å; Y309-V313 PolarHBondContact O-N 3.34Å; N310-V313 PolarHBondContact O-N 3.03Å; V313-A315 VanDerWaalsContact C-N 3.34Å; V313-A315 PolarHBondContact O-N 3.22Å; V313-I316 PolarHBondContact O-N 3.34Å; V313-A317 WeakPolarHBondContact O-CB 3.49Å; V313-A317 PolarHBondContact O-N 3.06Å; V313-Y367 HydrophobicContact CB-CD1 4.18Å; V313-Y367 HydrophobicContact CB-CE1 4.46Å; V313-Y367 HydrophobicContact CB-CG 4.37Å; V313-Y367 HydrophobicContact CG1-CD1 3.9Å; V313-Y367 HydrophobicContact CG1-CG 4.2Å; V313-Y367 HydrophobicContact CG2-CD1 3.61Å; V313-Y367 HydrophobicContact CG2-CD2 3.55Å; V313-Y367 HydrophobicContact CG2-CE1 3.93Å; V313-Y367 HydrophobicContact CG2-CE2 3.89Å; V313-Y367 HydrophobicContact CG2-CG 3.4Å; V313-Y370 HydrophobicContact CG1-CD1 3.72Å; V313-Y370 HydrophobicContact CG1-CE1 4.24Å; V313-L371 HydrophobicContact CG1-CD2 4.29Å
314	E	96.1	Very high	93.4	Very high	10 Å²	10	45.9 Å²	45.9	5%	0.047	26%	0.258	C	S	.	.	H	α-helix	trans	-64.6	-37.9	179.2	-164.7	54.9	-130.6	0	0	112.4	A34 Y152 N310 G311 A317 T318 Y370 K374	A34-E314 HydrophobicContact CB-CB 4.35Å; Y152-E314 HydrophobicContact CE1-CG 3.62Å; Y152-E314 WeakPolarHBondContact OH-CG 3.49Å; Y152-E314 PolarHBondContact OH-OE1 3.26Å; N310-E314 VanDerWaalsContact O-CB 3.3Å; N310-E314 WeakPolarHBondContact O-CB 3.45Å; N310-E314 PolarHBondContact O-N 3.36Å; G311-E314 PolarHBondContact O-N 3.38Å; E314-A317 PolarHBondContact O-N 3.33Å; E314-T318 WeakPolarHBondContact O-CB 3.49Å; E314-T318 PolarHBondContact O-N 3.3Å; E314-T318 PolarHBondContact O-OG1 2.91Å; E314-Y370 PolarHBondContact OE1-OH 3.21Å; E314-Y370 VanDerWaalsContact OE2-CE1 3.29Å; E314-Y370 WeakPolarHBondContact OE2-CE1 3.3Å; E314-Y370 PolarHBondContact OE2-OH 3.32Å; E314-K374 IonicContact OE1-NZ 2.59Å; E314-K374 PolarHBondContact OE1-NZ 2.86Å
315	A	96.3	Very high	93.8	Very high	7 Å²	7	41.9 Å²	41.9	6%	0.058	24%	0.243	C	C	.	.	H	α-helix	trans	-62.5	-50.5	173.1	0	0	0	0	0	111.8	T153 V157 G311 A312 V313 A317 T318 F319	T153-A315 HydrophobicContact CG2-CB 4.16Å; V157-A315 HydrophobicContact CG2-CB 3.75Å; G311-A315 WeakPolarHBondContact O-CB 3.48Å; G311-A315 PolarHBondContact O-N 2.95Å; A312-A315 PolarHBondContact O-N 2.85Å; V313-A315 VanDerWaalsContact C-N 3.34Å; V313-A315 PolarHBondContact O-N 3.22Å; A315-A317 VanDerWaalsContact C-N 3.32Å; A315-A317 PolarHBondContact O-N 3.26Å; A315-T318 PolarHBondContact O-N 3.47Å; A315-F319 WeakPolarHBondContact O-CB 3.45Å; A315-F319 PolarHBondContact O-N 3.45Å
316	I	96.7	Very high	94.1	Very high	98 Å²	98	41.3 Å²	41.3	50%	0.503	23%	0.234	S	C	.	.	H	α-helix	trans	-63.4	-40.9	178.5	-65.2	165.4	0	0	0	110.3	A312 V313 T318 F319 G320 L371	A312-I316 VanDerWaalsContact O-CG1 3.25Å; A312-I316 WeakPolarHBondContact O-CG1 3.46Å; A312-I316 PolarHBondContact O-N 3.4Å; V313-I316 PolarHBondContact O-N 3.34Å; I316-T318 VanDerWaalsContact C-N 3.34Å; I316-T318 PolarHBondContact O-N 3.04Å; I316-F319 PolarHBondContact O-N 3.4Å; I316-G320 PolarHBondContact O-N 2.93Å; I316-L371 HydrophobicContact CB-CD2 4.11Å; I316-L371 HydrophobicContact CG2-CD1 3.95Å; I316-L371 HydrophobicContact CG2-CD2 3.83Å
317	A	96.6	Very high	94.4	Very high	0 Å²	0	41.1 Å²	41.1	0%	0	23%	0.233	C	C	.	.	H	α-helix	trans	-63.9	-42.3	179.5	0	0	0	0	0	110.9	V313 E314 A315 G321 Y370 L371 K374	V313-A317 WeakPolarHBondContact O-CB 3.49Å; V313-A317 PolarHBondContact O-N 3.06Å; E314-A317 PolarHBondContact O-N 3.33Å; A315-A317 VanDerWaalsContact C-N 3.32Å; A315-A317 PolarHBondContact O-N 3.26Å; A317-G321 PolarHBondContact O-N 3.35Å; A317-Y370 HydrophobicContact CB-CD1 4.14Å; A317-Y370 HydrophobicContact CB-CE1 3.67Å; A317-L371 HydrophobicContact CB-CD2 3.51Å; A317-K374 HydrophobicContact CB-CB 4.27Å; A317-K374 HydrophobicContact CB-CD 3.4Å; A317-K374 HydrophobicContact CB-CG 4.28Å
318	T	93.7	Very high	94.5	Very high	9 Å²	9	37.7 Å²	37.7	6%	0.055	21%	0.208	C	C	.	.	H	α-helix	trans	-65.3	-46.1	177.1	-58.4	0	0	0	0	111.4	L149 Y152 T153 E314 A315 I316 G321 A322 K374	L149-T318 HydrophobicContact CD2-CG2 3.87Å; Y152-T318 HydrophobicContact CD1-CG2 4.03Å; Y152-T318 WeakPolarHBondContact CD1-OG1 3.41Å; Y152-T318 WeakPolarHBondContact CE1-OG1 3.35Å; T153-T318 WeakPolarHBondContact OG1-CG2 3.49Å; E314-T318 WeakPolarHBondContact O-CB 3.49Å; E314-T318 PolarHBondContact O-N 3.3Å; E314-T318 PolarHBondContact O-OG1 2.91Å; A315-T318 PolarHBondContact O-N 3.47Å; I316-T318 VanDerWaalsContact C-N 3.34Å; I316-T318 PolarHBondContact O-N 3.04Å; T318-G321 PolarHBondContact O-N 2.84Å; T318-A322 PolarHBondContact O-N 2.84Å; T318-K374 PolarHBondContact OG1-NZ 3.47Å
319	F	92.3	Very high	94.2	Very high	134 Å²	134	40.6 Å²	40.6	59%	0.588	24%	0.24	S	C	*	.	H	α-helix	trans	-63.8	-44.2	176.3	-177.7	-99.9	0	0	0	112.1	A315 I316 A322 L323	A315-F319 WeakPolarHBondContact O-CB 3.45Å; A315-F319 PolarHBondContact O-N 3.45Å; I316-F319 PolarHBondContact O-N 3.4Å; F319-A322 PolarHBondContact O-N 3.34Å; F319-L323 WeakPolarHBondContact O-CB 3.31Å; F319-L323 PolarHBondContact O-N 3.46Å
320	G	93.8	Very high	94	Very high	19 Å²	19	44.6 Å²	44.6	20%	0.196	26%	0.256	C	S	.	.	H	α-helix	trans	-61.6	-42.4	176.5	0	0	0	0	0	112.3	I316 L323 A324	I316-G320 PolarHBondContact O-N 2.93Å; G320-L323 PolarHBondContact O-N 3.44Å; G320-A324 VanDerWaalsContact O-CB 3.27Å; G320-A324 WeakPolarHBondContact O-CB 3.42Å; G320-A324 PolarHBondContact O-N 2.62Å
321	G	94.8	Very high	93.7	Very high	3 Å²	3	48 Å²	48	3%	0.031	27%	0.274	C	S	.	.	H	α-helix	trans	-60.3	-46	172.6	0	0	0	0	0	112.6	A317 T318 A324 S325 S378	A317-G321 PolarHBondContact O-N 3.35Å; T318-G321 PolarHBondContact O-N 2.84Å; G321-A324 PolarHBondContact O-N 3.35Å; G321-S325 PolarHBondContact O-N 2.9Å; G321-S325 PolarHBondContact O-OG 3.44Å; G321-S378 WeakPolarHBondContact CA-OG 3.33Å; G321-S378 WeakPolarHBondContact O-CB 3.48Å
322	A	93	Very high	93.3	Very high	38 Å²	38	58.1 Å²	58.1	31%	0.314	32%	0.318	S	S	.	.	H	α-helix	trans	-63	-43.2	177	0	0	0	0	0	112.4	L149 T318 F319 A324 S325 F326	L149-A322 HydrophobicContact CD1-CB 4.43Å; T318-A322 PolarHBondContact O-N 2.84Å; F319-A322 PolarHBondContact O-N 3.34Å; A322-A324 VanDerWaalsContact C-N 3.34Å; A322-S325 PolarHBondContact O-N 3.06Å; A322-F326 WeakPolarHBondContact O-CB 3.4Å; A322-F326 PolarHBondContact O-N 3.39Å
323	L	93.4	Very high	92.9	Very high	100 Å²	100	59 Å²	59	52%	0.524	32%	0.32	S	S	.	.	H	α-helix	trans	-64	-40.1	176.1	-177.3	61.8	0	0	0	111.6	F319 G320 F326 S327	F319-L323 WeakPolarHBondContact O-CB 3.31Å; F319-L323 PolarHBondContact O-N 3.46Å; G320-L323 PolarHBondContact O-N 3.44Å; L323-F326 PolarHBondContact O-N 3.31Å; L323-S327 PolarHBondContact O-N 2.88Å
324	A	94.8	Very high	92.5	Very high	17 Å²	17	62.9 Å²	62.9	14%	0.14	34%	0.34	C	S	.	.	H	α-helix	trans	-62.5	-48.1	175.8	0	0	0	0	0	111	G320 G321 A322 F326 S327 S375 F379	G320-A324 VanDerWaalsContact O-CB 3.27Å; G320-A324 WeakPolarHBondContact O-CB 3.42Å; G320-A324 PolarHBondContact O-N 2.62Å; G321-A324 PolarHBondContact O-N 3.35Å; A322-A324 VanDerWaalsContact C-N 3.34Å; A324-F326 VanDerWaalsContact C-N 3.33Å; A324-F326 PolarHBondContact O-N 3.47Å; A324-S327 WeakPolarHBondContact O-CB 3.27Å; A324-S327 PolarHBondContact O-N 3.29Å; A324-S327 PolarHBondContact O-OG 3.4Å; A324-S375 WeakPolarHBondContact CB-O 3.21Å; A324-F379 HydrophobicContact CB-CB 4.12Å
325	S	93.4	Very high	92	Very high	36 Å²	36	64 Å²	64	25%	0.252	34%	0.344	S	S	.	.	H	α-helix	trans	-58.4	-42.9	173.3	-67	0	0	0	0	112.5	G321 A322 S327 V328 S378 T382	G321-S325 PolarHBondContact O-N 2.9Å; G321-S325 PolarHBondContact O-OG 3.44Å; A322-S325 PolarHBondContact O-N 3.06Å; S325-S327 VanDerWaalsContact C-N 3.32Å; S325-S327 PolarHBondContact O-N 2.87Å; S325-V328 WeakPolarHBondContact O-CB 3.43Å; S325-V328 PolarHBondContact O-N 3.5Å; S325-S378 PolarHBondContact OG-O 3.44Å; S325-T382 VanDerWaalsContact CB-OG1 3.3Å; S325-T382 WeakPolarHBondContact CB-OG1 3.3Å; S325-T382 PolarHBondContact OG-OG1 2.93Å
326	F	91.4	Very high	91.4	Very high	127 Å²	127	69 Å²	69	56%	0.557	37%	0.37	S	S	*	.	H	α-helix	trans	-62.7	-38.6	177.6	-176.8	-107	0	0	0	112.2	A322 L323 A324 V328 G329 Y330	A322-F326 WeakPolarHBondContact O-CB 3.4Å; A322-F326 PolarHBondContact O-N 3.39Å; L323-F326 PolarHBondContact O-N 3.31Å; A324-F326 VanDerWaalsContact C-N 3.33Å; A324-F326 PolarHBondContact O-N 3.47Å; F326-V328 PolarHBondContact O-N 3.1Å; F326-G329 PolarHBondContact O-N 3.25Å; F326-G329 VanDerWaalsContact O-N 3.13Å; F326-Y330 HydrophobicContact CD1-CD2 4.45Å; F326-Y330 AromaticContact CD1-CE2 3.84Å; F326-Y330 HydrophobicContact CD1-CE2 3.84Å; F326-Y330 HydrophobicContact CE1-CD2 4.26Å; F326-Y330 AromaticContact CE1-CE2 3.3Å; F326-Y330 HydrophobicContact CE1-CE2 3.3Å; F326-Y330 AromaticContact CE1-CZ 3.88Å; F326-Y330 HydrophobicContact CE2-CE2 4.07Å; F326-Y330 HydrophobicContact CG-CE2 4.45Å; F326-Y330 AromaticContact CZ-CE2 3.44Å; F326-Y330 HydrophobicContact CZ-CE2 3.44Å; F326-Y330 VanDerWaalsContact CZ-CE2 3.44Å; F326-Y330 AromaticContact CZ-CZ 3.77Å; F326-Y330 WeakPolarHBondContact CZ-OH 3.4Å
327	S	92.8	Very high	90.9	Very high	44 Å²	44	67 Å²	67	31%	0.308	36%	0.36	S	S	.	.	H	α-helix	trans	-61	-28.4	-180	78	0	0	0	0	113.5	L323 A324 S325 G329 Y330	L323-S327 PolarHBondContact O-N 2.88Å; A324-S327 WeakPolarHBondContact O-CB 3.27Å; A324-S327 PolarHBondContact O-N 3.29Å; A324-S327 PolarHBondContact O-OG 3.4Å; S325-S327 VanDerWaalsContact C-N 3.32Å; S325-S327 PolarHBondContact O-N 2.87Å; S327-G329 PolarHBondContact O-N 2.64Å; S327-Y330 PolarHBondContact O-N 2.87Å
328	V	91	Very high	90.7	Very high	15 Å²	15	70.1 Å²	70.1	9%	0.091	38%	0.376	C	S	.	.	H	α-helix	trans	-56.6	-36.6	176.8	179	0	0	0	0	111.4	S325 F326 Y330 L331 F379 T382 I383	S325-V328 WeakPolarHBondContact O-CB 3.43Å; S325-V328 PolarHBondContact O-N 3.5Å; F326-V328 PolarHBondContact O-N 3.1Å; V328-Y330 PolarHBondContact O-N 3.49Å; V328-L331 PolarHBondContact O-N 2.92Å; V328-F379 HydrophobicContact CG2-CD2 3.58Å; V328-F379 HydrophobicContact CG2-CE2 3.61Å; V328-F379 HydrophobicContact CG2-CG 4.37Å; V328-F379 HydrophobicContact CG2-CZ 4.43Å; V328-T382 HydrophobicContact CB-CG2 4.09Å; V328-T382 HydrophobicContact CG1-CG2 4.27Å; V328-T382 HydrophobicContact CG2-CG2 4.05Å; V328-I383 HydrophobicContact CB-CG1 4.43Å; V328-I383 HydrophobicContact CG1-CG1 3.63Å; V328-I383 HydrophobicContact CG2-CD1 4.28Å; V328-I383 HydrophobicContact CG2-CG1 3.86Å
329	G	87.6	Confident	90.6	Very high	72 Å²	72	69.8 Å²	69.8	74%	0.742	37%	0.374	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.4	-16.8	179.4	0	0	0	0	0	114.7	F326 S327	F326-G329 PolarHBondContact O-N 3.25Å; F326-G329 VanDerWaalsContact O-N 3.13Å; S327-G329 PolarHBondContact O-N 2.64Å
330	Y	90.4	Very high	90.6	Very high	165 Å²	165	64.3 Å²	64.3	65%	0.647	35%	0.35	S	S	*	.	T	Hydrogen-bonded Turn	trans	-101.8	-8.6	180	-65.9	-89.4	0	0	0	113.3	F326 S327 V328 K332	F326-Y330 HydrophobicContact CD1-CD2 4.45Å; F326-Y330 AromaticContact CD1-CE2 3.84Å; F326-Y330 HydrophobicContact CD1-CE2 3.84Å; F326-Y330 HydrophobicContact CE1-CD2 4.26Å; F326-Y330 AromaticContact CE1-CE2 3.3Å; F326-Y330 HydrophobicContact CE1-CE2 3.3Å; F326-Y330 AromaticContact CE1-CZ 3.88Å; F326-Y330 HydrophobicContact CE2-CE2 4.07Å; F326-Y330 HydrophobicContact CG-CE2 4.45Å; F326-Y330 AromaticContact CZ-CE2 3.44Å; F326-Y330 HydrophobicContact CZ-CE2 3.44Å; F326-Y330 VanDerWaalsContact CZ-CE2 3.44Å; F326-Y330 AromaticContact CZ-CZ 3.77Å; F326-Y330 WeakPolarHBondContact CZ-OH 3.4Å; S327-Y330 PolarHBondContact O-N 2.87Å; V328-Y330 PolarHBondContact O-N 3.49Å; Y330-K332 PolarHBondContact O-N 3.03Å
331	L	88.7	Confident	90.6	Very high	72 Å²	72	66.2 Å²	66.2	38%	0.377	36%	0.356	S	S	.	.			trans	-82.8	110.3	-177.8	-69.6	177.8	0	0	0	111.3	V328 V333 W335 F379	V328-L331 PolarHBondContact O-N 2.92Å; L331-V333 VanDerWaalsContact C-N 3.3Å; L331-V333 HydrophobicContact CB-CG2 4.13Å; L331-V333 PolarHBondContact O-N 3.24Å; L331-V333 VanDerWaalsContact O-N 3.15Å; L331-W335 HydrophobicContact CB-CZ2 3.97Å; L331-W335 HydrophobicContact CD1-CH2 4.03Å; L331-W335 HydrophobicContact CD1-CZ2 3.98Å; L331-F379 HydrophobicContact CD1-CE2 3.58Å; L331-F379 HydrophobicContact CD1-CZ 3.45Å; L331-F379 VanDerWaalsContact CD1-CZ 3.45Å
332	K	88	Confident	90.6	Very high	213 Å²	213	66.7 Å²	66.7	93%	0.926	36%	0.361	S	S	*	.			trans	-87.1	69.4	170.7	-63.6	-176.1	-178.1	179.2	0	110.5	Y330	Y330-K332 PolarHBondContact O-N 3.03Å
333	V	88	Confident	90.7	Very high	49 Å²	49	65 Å²	65	30%	0.297	35%	0.346	S	S	.	.			trans	-111.3	139.3	-178	177.7	0	0	0	0	109.4	L331 W335 L338	L331-V333 VanDerWaalsContact C-N 3.3Å; L331-V333 HydrophobicContact CB-CG2 4.13Å; L331-V333 PolarHBondContact O-N 3.24Å; L331-V333 VanDerWaalsContact O-N 3.15Å; V333-W335 VanDerWaalsContact C-N 3.32Å; V333-W335 HydrophobicContact CB-CD2 4.2Å; V333-W335 HydrophobicContact CB-CH2 4.33Å; V333-W335 HydrophobicContact CB-CZ2 4Å; V333-W335 HydrophobicContact CG1-CD2 4.18Å; V333-W335 HydrophobicContact CG1-CE3 4.11Å; V333-W335 HydrophobicContact CG1-CH2 4.45Å; V333-W335 HydrophobicContact CG1-CZ3 4.25Å; V333-W335 HydrophobicContact CG2-CZ2 4.4Å; V333-W335 VanDerWaalsContact O-CD1 3.32Å; V333-W335 PolarHBondContact O-N 3.48Å; V333-L338 HydrophobicContact CG1-CB 3.87Å; V333-L338 HydrophobicContact CG1-CD1 3.8Å; V333-L338 HydrophobicContact CG1-CG 4.44Å
334	N	89	Confident	90.9	Very high	92 Å²	92	60.3 Å²	60.3	49%	0.492	32%	0.323	S	S	.	.			trans	-74.2	91	168.2	-176.3	-15.6	0	0	0	108.8	D336 L337 L338	N334-D336 PolarHBondContact O-N 2.73Å; N334-D336 WeakPolarHBondContact OD1-CB 3.45Å; N334-D336 PolarHBondContact OD1-N 2.97Å; N334-D336 VanDerWaalsContact OD1-N 3.13Å; N334-L337 HydrophobicContact CB-CB 4.38Å; N334-L337 PolarHBondContact O-N 2.91Å; N334-L337 VanDerWaalsContact O-N 3.15Å; N334-L337 PolarHBondContact OD1-N 3.33Å; N334-L338 PolarHBondContact O-N 3.46Å
335	W	86.4	Confident	91	Very high	35 Å²	35	63 Å²	63	13%	0.133	34%	0.337	C	S	.	.	H	α-helix	trans	-66.6	-21.8	-178.4	-64.7	114.3	0	0	0	113.5	L331 V333 L337 G339 F379 I383	L331-W335 HydrophobicContact CB-CZ2 3.97Å; L331-W335 HydrophobicContact CD1-CH2 4.03Å; L331-W335 HydrophobicContact CD1-CZ2 3.98Å; V333-W335 VanDerWaalsContact C-N 3.32Å; V333-W335 HydrophobicContact CB-CD2 4.2Å; V333-W335 HydrophobicContact CB-CH2 4.33Å; V333-W335 HydrophobicContact CB-CZ2 4Å; V333-W335 HydrophobicContact CG1-CD2 4.18Å; V333-W335 HydrophobicContact CG1-CE3 4.11Å; V333-W335 HydrophobicContact CG1-CH2 4.45Å; V333-W335 HydrophobicContact CG1-CZ3 4.25Å; V333-W335 HydrophobicContact CG2-CZ2 4.4Å; V333-W335 VanDerWaalsContact O-CD1 3.32Å; V333-W335 PolarHBondContact O-N 3.48Å; W335-L337 VanDerWaalsContact C-N 3.28Å; W335-L337 PolarHBondContact O-N 2.93Å; W335-G339 WeakPolarHBondContact O-CA 3.1Å; W335-G339 PolarHBondContact O-N 2.77Å; W335-F379 HydrophobicContact CH2-CZ 4.25Å; W335-I383 HydrophobicContact CD2-CG2 4.08Å; W335-I383 HydrophobicContact CE3-CD1 4.41Å; W335-I383 HydrophobicContact CE3-CG2 3.93Å; W335-I383 HydrophobicContact CH2-CD1 3.36Å; W335-I383 HydrophobicContact CH2-CG1 4.04Å; W335-I383 HydrophobicContact CZ2-CD1 3.97Å; W335-I383 HydrophobicContact CZ2-CG1 4.17Å; W335-I383 HydrophobicContact CZ3-CD1 3.62Å; W335-I383 HydrophobicContact CZ3-CG1 4.36Å; W335-I383 HydrophobicContact CZ3-CG2 4.22Å
336	D	84.1	Confident	91.2	Very high	110 Å²	110	64.4 Å²	64.4	59%	0.588	34%	0.339	S	S	*	.	H	α-helix	trans	-67.3	-32.6	173.3	-58.1	-35.6	0	0	0	111.6	H271 N334	H271-D336 IonicContact NE2-OD1 3.88Å; N334-D336 PolarHBondContact O-N 2.73Å; N334-D336 WeakPolarHBondContact OD1-CB 3.45Å; N334-D336 PolarHBondContact OD1-N 2.97Å; N334-D336 VanDerWaalsContact OD1-N 3.13Å
337	L	86.6	Confident	91.5	Very high	57 Å²	57	58.4 Å²	58.4	30%	0.298	31%	0.312	S	S	.	.	H	α-helix	trans	-93	-42.5	-179.9	-174.1	67.3	0	0	0	112.7	N334 W335 I454 L455 A458	N334-L337 HydrophobicContact CB-CB 4.38Å; N334-L337 PolarHBondContact O-N 2.91Å; N334-L337 VanDerWaalsContact O-N 3.15Å; N334-L337 PolarHBondContact OD1-N 3.33Å; W335-L337 VanDerWaalsContact C-N 3.28Å; W335-L337 PolarHBondContact O-N 2.93Å; L337-I454 HydrophobicContact CD1-CG2 4.14Å; L337-L455 HydrophobicContact CD1-CD1 3.86Å; L337-L455 HydrophobicContact CD2-CD1 4.39Å; L337-L455 HydrophobicContact CG-CD1 3.87Å; L337-A458 HydrophobicContact CD1-CB 3.77Å
338	L	92.1	Very high	91.8	Very high	66 Å²	66	58.7 Å²	58.7	35%	0.346	32%	0.317	S	S	.	.	H	α-helix	trans	-105.7	-6.5	-171.1	-65.3	175.3	0	0	0	113.5	V333 N334 L341 G342 L455	V333-L338 HydrophobicContact CG1-CB 3.87Å; V333-L338 HydrophobicContact CG1-CD1 3.8Å; V333-L338 HydrophobicContact CG1-CG 4.44Å; N334-L338 PolarHBondContact O-N 3.46Å; L338-L341 HydrophobicContact CD2-CD2 4.07Å; L338-L341 WeakPolarHBondContact O-CB 3.35Å; L338-L341 PolarHBondContact O-N 3.33Å; L338-G342 PolarHBondContact O-N 3.49Å; L338-L455 HydrophobicContact CD2-CD1 4.32Å
339	G	91.3	Very high	92.1	Very high	1 Å²	1	60.5 Å²	60.5	1%	0.01	33%	0.328	C	S	.	.	H	α-helix	trans	-59.3	-50.4	-178.8	0	0	0	0	0	112.6	W335 L341 G342 L343	W335-G339 WeakPolarHBondContact O-CA 3.1Å; W335-G339 PolarHBondContact O-N 2.77Å; G339-L341 VanDerWaalsContact C-N 3.26Å; G339-L341 PolarHBondContact O-N 3.4Å; G339-G342 WeakPolarHBondContact O-CA 3.28Å; G339-G342 PolarHBondContact O-N 2.99Å; G339-L343 WeakPolarHBondContact O-CG 3.3Å; G339-L343 PolarHBondContact O-N 3.42Å
340	E	91.6	Very high	92.7	Very high	19 Å²	19	57 Å²	57	9%	0.089	29%	0.293	C	S	.	.	H	α-helix	trans	-64.5	-31.2	177.8	-64.6	-164.9	174.6	0	0	112.8	L343 A344 F447 R450 S451 I454	E340-L343 PolarHBondContact O-N 3.33Å; E340-A344 WeakPolarHBondContact O-CB 3.45Å; E340-A344 PolarHBondContact O-N 3.21Å; E340-F447 HydrophobicContact CB-CD1 4.4Å; E340-F447 HydrophobicContact CG-CD1 4.32Å; E340-R450 IonicContact OE1-CZ 3.32Å; E340-R450 IonicContact OE1-NE 3.03Å; E340-R450 PolarHBondContact OE1-NE 3.49Å; E340-R450 IonicContact OE1-NH2 2.74Å; E340-R450 PolarHBondContact OE1-NH2 2.86Å; E340-R450 WeakPolarHBondContact OE2-CB 3.34Å; E340-R450 IonicContact OE2-CZ 3.93Å; E340-R450 IonicContact OE2-NE 3.3Å; E340-R450 PolarHBondContact OE2-NE 2.97Å; E340-R450 IonicContact OE2-NH2 3.81Å; E340-S451 PolarHBondContact OE2-N 3.46Å; E340-I454 HydrophobicContact CG-CD1 4.02Å; E340-I454 WeakPolarHBondContact OE1-CD1 3.46Å; E340-I454 WeakPolarHBondContact OE2-CD1 3.38Å
341	L	94.5	Very high	93.1	Very high	59 Å²	59	49.4 Å²	49.4	31%	0.309	26%	0.264	S	S	.	.	H	α-helix	trans	-65.4	-44.1	171.9	-174.3	59.3	0	0	0	110.7	L338 G339 A344 V345 S451	L338-L341 HydrophobicContact CD2-CD2 4.07Å; L338-L341 WeakPolarHBondContact O-CB 3.35Å; L338-L341 PolarHBondContact O-N 3.33Å; G339-L341 VanDerWaalsContact C-N 3.26Å; G339-L341 PolarHBondContact O-N 3.4Å; L341-A344 PolarHBondContact O-N 2.93Å; L341-V345 HydrophobicContact CD1-CG2 4.2Å; L341-V345 HydrophobicContact CG-CG2 4.33Å; L341-V345 WeakPolarHBondContact O-CG2 3.44Å; L341-V345 PolarHBondContact O-N 3.11Å; L341-S451 WeakPolarHBondContact CA-OG 3.41Å; L341-S451 VanDerWaalsContact CB-OG 3.26Å; L341-S451 WeakPolarHBondContact CB-OG 3.46Å; L341-S451 PolarHBondContact N-OG 3.44Å
342	G	94.6	Very high	93.5	Very high	14 Å²	14	47.9 Å²	47.9	14%	0.144	27%	0.266	C	S	.	.	H	α-helix	trans	-58.5	-47.7	175.2	0	0	0	0	0	111.8	L338 G339 A344 V345 F346	L338-G342 PolarHBondContact O-N 3.49Å; G339-G342 WeakPolarHBondContact O-CA 3.28Å; G339-G342 PolarHBondContact O-N 2.99Å; G342-A344 VanDerWaalsContact C-N 3.31Å; G342-A344 PolarHBondContact O-N 3.19Å; G342-V345 PolarHBondContact O-N 3.39Å; G342-F346 WeakPolarHBondContact O-CD2 3.32Å; G342-F346 PolarHBondContact O-N 2.91Å
343	L	95.3	Very high	94	Very high	1 Å²	1	38 Å²	38	1%	0.005	22%	0.223	C	C	.	.	H	α-helix	trans	-55.4	-47.3	175.4	-67.2	-178.3	0	0	0	111.1	W275 W278 G339 E340 S347 L380 F447	W275-L343 HydrophobicContact CD2-CD1 4.41Å; W275-L343 HydrophobicContact CE3-CD1 3.89Å; W275-L343 HydrophobicContact CE3-CD2 4.05Å; W275-L343 HydrophobicContact CE3-CG 4.33Å; W275-L343 HydrophobicContact CH2-CD1 4.15Å; W275-L343 HydrophobicContact CH2-CD2 4.09Å; W275-L343 HydrophobicContact CH2-CG 4Å; W275-L343 HydrophobicContact CZ3-CD1 3.78Å; W275-L343 HydrophobicContact CZ3-CD2 3.4Å; W275-L343 VanDerWaalsContact CZ3-CD2 3.4Å; W275-L343 HydrophobicContact CZ3-CG 3.72Å; W278-L343 HydrophobicContact CB-CD1 3.97Å; W278-L343 HydrophobicContact CD2-CD1 4.41Å; W278-L343 HydrophobicContact CD2-CD2 3.41Å; W278-L343 VanDerWaalsContact CD2-CD2 3.41Å; W278-L343 HydrophobicContact CD2-CG 4.42Å; W278-L343 HydrophobicContact CE3-CD2 3.85Å; W278-L343 HydrophobicContact CG-CD1 3.82Å; W278-L343 HydrophobicContact CG-CD2 3.69Å; W278-L343 HydrophobicContact CG-CG 4.22Å; W278-L343 HydrophobicContact CZ2-CD2 4.22Å; W278-L343 HydrophobicContact CZ3-CD2 4.42Å; G339-L343 WeakPolarHBondContact O-CG 3.3Å; G339-L343 PolarHBondContact O-N 3.42Å; E340-L343 PolarHBondContact O-N 3.33Å; L343-S347 WeakPolarHBondContact O-CB 3.41Å; L343-S347 PolarHBondContact O-N 3.19Å; L343-S347 PolarHBondContact O-OG 2.59Å; L343-L380 HydrophobicContact CD2-CD1 4.44Å; L343-L380 HydrophobicContact CD2-CD2 4.04Å; L343-F447 HydrophobicContact CB-CB 4.24Å; L343-F447 HydrophobicContact CB-CD1 4.13Å; L343-F447 HydrophobicContact CB-CG 4.09Å; L343-F447 HydrophobicContact CD1-CD1 3.61Å; L343-F447 HydrophobicContact CD1-CE1 3.54Å; L343-F447 HydrophobicContact CD1-CG 4.28Å; L343-F447 HydrophobicContact CD1-CZ 4.17Å
344	A	96.8	Very high	94.5	Very high	3 Å²	3	35.7 Å²	35.7	3%	0.025	21%	0.209	C	C	.	.	H	α-helix	trans	-62.5	-51.3	179	0	0	0	0	0	112.7	E340 L341 G342 S347 A348 F447 L448	E340-A344 WeakPolarHBondContact O-CB 3.45Å; E340-A344 PolarHBondContact O-N 3.21Å; L341-A344 PolarHBondContact O-N 2.93Å; G342-A344 VanDerWaalsContact C-N 3.31Å; G342-A344 PolarHBondContact O-N 3.19Å; A344-S347 PolarHBondContact O-N 3.24Å; A344-A348 WeakPolarHBondContact O-CB 3.26Å; A344-A348 PolarHBondContact O-N 3.22Å; A344-F447 HydrophobicContact CB-CB 4.04Å; A344-L448 HydrophobicContact CB-CB 3.96Å; A344-L448 HydrophobicContact CB-CD1 4.43Å
345	V	97.4	Very high	95	Very high	74 Å²	74	34.1 Å²	34.1	45%	0.448	20%	0.198	S	C	.	.	H	α-helix	trans	-62	-51.7	-176.5	169.5	0	0	0	0	111.3	L341 G342 A348 V349	L341-V345 HydrophobicContact CD1-CG2 4.2Å; L341-V345 HydrophobicContact CG-CG2 4.33Å; L341-V345 WeakPolarHBondContact O-CG2 3.44Å; L341-V345 PolarHBondContact O-N 3.11Å; G342-V345 PolarHBondContact O-N 3.39Å; V345-A348 WeakPolarHBondContact O-CB 3.37Å; V345-A348 PolarHBondContact O-N 2.67Å; V345-V349 WeakPolarHBondContact O-CG2 3.37Å; V345-V349 PolarHBondContact O-N 2.71Å
346	F	97.4	Very high	95.5	Very high	65 Å²	65	37 Å²	37	29%	0.285	22%	0.216	S	C	.	.	H	α-helix	trans	-74.8	-27.5	-176.6	-78.6	-83.1	0	0	0	112.2	G342 A348 V349 I350 F379 L380	G342-F346 WeakPolarHBondContact O-CD2 3.32Å; G342-F346 PolarHBondContact O-N 2.91Å; F346-A348 VanDerWaalsContact C-N 3.33Å; F346-V349 PolarHBondContact O-N 2.98Å; F346-I350 WeakPolarHBondContact O-CG1 3.48Å; F346-I350 PolarHBondContact O-N 3.03Å; F346-F379 HydrophobicContact CD1-CD1 4.43Å; F346-F379 HydrophobicContact CD2-CD1 4.07Å; F346-F379 HydrophobicContact CD2-CE1 4.02Å; F346-F379 HydrophobicContact CE1-CD1 4.2Å; F346-F379 AromaticContact CE2-CD1 3.83Å; F346-F379 HydrophobicContact CE2-CD1 3.83Å; F346-F379 AromaticContact CE2-CE1 3.48Å; F346-F379 HydrophobicContact CE2-CE1 3.48Å; F346-F379 VanDerWaalsContact CE2-CE1 3.48Å; F346-F379 HydrophobicContact CE2-CZ 4.39Å; F346-F379 HydrophobicContact CG-CD1 4.36Å; F346-F379 AromaticContact CZ-CD1 3.89Å; F346-F379 HydrophobicContact CZ-CD1 3.89Å; F346-F379 AromaticContact CZ-CE1 3.76Å; F346-F379 HydrophobicContact CZ-CE1 3.76Å; F346-F379 HydrophobicContact CZ-CZ 4.45Å; F346-L380 HydrophobicContact CB-CD1 3.47Å; F346-L380 VanDerWaalsContact CB-CD1 3.47Å; F346-L380 HydrophobicContact CB-CD2 3.81Å; F346-L380 HydrophobicContact CB-CG 3.62Å; F346-L380 HydrophobicContact CD2-CD2 4.07Å; F346-L380 HydrophobicContact CG-CD2 4.19Å; F346-L380 HydrophobicContact CG-CG 4.27Å
347	S	98.2	Very high	96.2	Very high	0 Å²	0	31.8 Å²	31.8	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-67.8	-34.5	169.5	-59.3	0	0	0	0	111.3	W278 L343 A344 I350 A351	W278-S347 PolarHBondContact NE1-OG 3.37Å; L343-S347 WeakPolarHBondContact O-CB 3.41Å; L343-S347 PolarHBondContact O-N 3.19Å; L343-S347 PolarHBondContact O-OG 2.59Å; A344-S347 PolarHBondContact O-N 3.24Å; S347-I350 PolarHBondContact O-N 2.89Å; S347-A351 PolarHBondContact O-N 3.49Å
348	A	98.3	Very high	96.6	Very high	50 Å²	50	29.6 Å²	29.6	41%	0.413	18%	0.177	S	C	.	.	H	α-helix	trans	-67.5	-36.8	171.1	0	0	0	0	0	112.2	A344 V345 F346 A351 G352 A444	A344-A348 WeakPolarHBondContact O-CB 3.26Å; A344-A348 PolarHBondContact O-N 3.22Å; V345-A348 WeakPolarHBondContact O-CB 3.37Å; V345-A348 PolarHBondContact O-N 2.67Å; F346-A348 VanDerWaalsContact C-N 3.33Å; A348-A351 PolarHBondContact O-N 3.36Å; A348-G352 PolarHBondContact O-N 3.38Å; A348-A444 HydrophobicContact CB-CB 3.98Å
349	V	98.5	Very high	96.8	Very high	53 Å²	53	34.6 Å²	34.6	32%	0.321	19%	0.192	S	C	.	.	H	α-helix	trans	-62.1	-43.1	172.4	172.1	0	0	0	0	111	V345 F346 S353	V345-V349 WeakPolarHBondContact O-CG2 3.37Å; V345-V349 PolarHBondContact O-N 2.71Å; F346-V349 PolarHBondContact O-N 2.98Å; V349-S353 WeakPolarHBondContact O-CB 3.42Å; V349-S353 PolarHBondContact O-N 3.27Å; V349-S353 PolarHBondContact O-OG 2.92Å
350	I	98.7	Very high	97	Very high	0 Å²	0	35.6 Å²	35.6	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-60.4	-50.6	174.4	-68.1	166.8	0	0	0	110.1	F346 S347 G352 S353 L354 V373 F440	F346-I350 WeakPolarHBondContact O-CG1 3.48Å; F346-I350 PolarHBondContact O-N 3.03Å; S347-I350 PolarHBondContact O-N 2.89Å; I350-G352 PolarHBondContact O-N 3.02Å; I350-S353 PolarHBondContact O-N 3.21Å; I350-L354 HydrophobicContact CG2-CD1 3.9Å; I350-L354 WeakPolarHBondContact O-CG 3.34Å; I350-L354 PolarHBondContact O-N 2.89Å; I350-V373 HydrophobicContact CG2-CG1 4.26Å; I350-V373 HydrophobicContact CG2-CG2 4.22Å; I350-F440 HydrophobicContact CB-CD1 4.19Å; I350-F440 HydrophobicContact CB-CG 4.3Å; I350-F440 HydrophobicContact CD1-CD1 4.37Å; I350-F440 HydrophobicContact CD1-CE1 4.13Å; I350-F440 HydrophobicContact CG2-CB 4.12Å; I350-F440 HydrophobicContact CG2-CD1 3.69Å; I350-F440 HydrophobicContact CG2-CD2 3.64Å; I350-F440 HydrophobicContact CG2-CE1 3.95Å; I350-F440 HydrophobicContact CG2-CE2 3.92Å; I350-F440 HydrophobicContact CG2-CG 3.53Å; I350-F440 HydrophobicContact CG2-CZ 4.05Å
351	A	98.7	Very high	97.1	Very high	4 Å²	4	45.7 Å²	45.7	3%	0.033	24%	0.236	C	C	.	.	H	α-helix	trans	-57.6	-48.9	178.5	0	0	0	0	0	112.5	S347 A348 S353 L354 F355 G437 F440 A441	S347-A351 PolarHBondContact O-N 3.49Å; A348-A351 PolarHBondContact O-N 3.36Å; A351-S353 VanDerWaalsContact C-N 3.31Å; A351-S353 PolarHBondContact O-N 3.43Å; A351-L354 PolarHBondContact O-N 3.29Å; A351-F355 HydrophobicContact CB-CE2 4.39Å; A351-F355 WeakPolarHBondContact O-CD2 3.46Å; A351-F355 WeakPolarHBondContact O-CG 3.06Å; A351-F355 PolarHBondContact O-N 3.19Å; A351-G437 WeakPolarHBondContact CB-O 3.27Å; A351-F440 HydrophobicContact CB-CB 3.88Å; A351-A441 HydrophobicContact CB-CB 4.04Å
352	G	98.6	Very high	97.1	Very high	40 Å²	40	45.1 Å²	45.1	41%	0.412	24%	0.237	S	C	.	.	H	α-helix	trans	-60.7	-39.6	177.7	0	0	0	0	0	112.7	A348 I350 F355 L356	A348-G352 PolarHBondContact O-N 3.38Å; I350-G352 PolarHBondContact O-N 3.02Å; G352-F355 PolarHBondContact O-N 2.89Å; G352-L356 WeakPolarHBondContact O-CB 3.21Å; G352-L356 PolarHBondContact O-N 2.9Å
353	S	98.5	Very high	97.2	Very high	6 Å²	6	45.6 Å²	45.6	4%	0.042	24%	0.236	C	C	.	.	H	α-helix	trans	-63.5	-43.7	175.5	-58.5	0	0	0	0	111.4	V349 I350 A351 L356 M357 L372	V349-S353 WeakPolarHBondContact O-CB 3.42Å; V349-S353 PolarHBondContact O-N 3.27Å; V349-S353 PolarHBondContact O-OG 2.92Å; I350-S353 PolarHBondContact O-N 3.21Å; A351-S353 VanDerWaalsContact C-N 3.31Å; A351-S353 PolarHBondContact O-N 3.43Å; S353-L356 WeakPolarHBondContact O-CB 3.48Å; S353-L356 PolarHBondContact O-N 3.01Å; S353-M357 WeakPolarHBondContact O-CG 3.24Å; S353-M357 PolarHBondContact O-N 3.23Å; S353-L372 WeakPolarHBondContact OG-CB 3.49Å
354	L	98.6	Very high	97.3	Very high	0 Å²	0	53.1 Å²	53.1	0%	0	27%	0.265	C	S	.	.	H	α-helix	trans	-66.1	-40.8	178.2	-66.5	167.2	0	0	0	112.5	I289 I350 A351 L356 M357 N358 V373 F433 F440	I289-L354 HydrophobicContact CD1-CD1 3.66Å; I289-L354 HydrophobicContact CD1-CD2 3.79Å; I289-L354 HydrophobicContact CD1-CG 4.26Å; I289-L354 HydrophobicContact CG1-CD1 4.29Å; I289-L354 HydrophobicContact CG1-CD2 3.83Å; I289-L354 HydrophobicContact CG2-CD2 4.23Å; I350-L354 HydrophobicContact CG2-CD1 3.9Å; I350-L354 WeakPolarHBondContact O-CG 3.34Å; I350-L354 PolarHBondContact O-N 2.89Å; A351-L354 PolarHBondContact O-N 3.29Å; L354-L356 VanDerWaalsContact C-N 3.33Å; L354-L356 PolarHBondContact O-N 2.95Å; L354-M357 HydrophobicContact CD2-SD 4.11Å; L354-M357 PolarHBondContact O-N 3.19Å; L354-N358 WeakPolarHBondContact O-CB 3.16Å; L354-N358 PolarHBondContact O-N 2.78Å; L354-V373 HydrophobicContact CD2-CG2 4.23Å; L354-V373 HydrophobicContact CG-CG2 4.24Å; L354-F433 HydrophobicContact CD2-CD1 3.7Å; L354-F433 HydrophobicContact CD2-CE1 3.84Å; L354-F440 HydrophobicContact CD1-CD2 3.81Å; L354-F440 HydrophobicContact CD1-CE2 4.42Å
355	F	98.4	Very high	97.3	Very high	60 Å²	60	55.1 Å²	55.1	26%	0.263	28%	0.276	S	S	.	.	H	α-helix	trans	-63	-41.3	173.3	-68.4	-47.6	0	0	0	111.8	A351 G352 N358 Y359 L434 A441	A351-F355 HydrophobicContact CB-CE2 4.39Å; A351-F355 WeakPolarHBondContact O-CD2 3.46Å; A351-F355 WeakPolarHBondContact O-CG 3.06Å; A351-F355 PolarHBondContact O-N 3.19Å; G352-F355 PolarHBondContact O-N 2.89Å; F355-N358 PolarHBondContact O-N 3.01Å; F355-Y359 WeakPolarHBondContact O-CD2 3.35Å; F355-Y359 PolarHBondContact O-N 2.84Å; F355-L434 HydrophobicContact CD1-CD1 3.91Å; F355-L434 HydrophobicContact CE1-CD1 3.8Å; F355-A441 HydrophobicContact CE2-CB 4.35Å
356	L	97.3	Very high	97.3	Very high	95 Å²	95	51.6 Å²	51.6	50%	0.497	26%	0.255	S	S	.	.	H	α-helix	trans	-62	-43.2	175.7	-175.5	66.8	0	0	0	111.5	G352 S353 L354 S360 V365	G352-L356 WeakPolarHBondContact O-CB 3.21Å; G352-L356 PolarHBondContact O-N 2.9Å; S353-L356 WeakPolarHBondContact O-CB 3.48Å; S353-L356 PolarHBondContact O-N 3.01Å; L354-L356 VanDerWaalsContact C-N 3.33Å; L354-L356 PolarHBondContact O-N 2.95Å; L356-S360 WeakPolarHBondContact O-CB 3.45Å; L356-S360 PolarHBondContact O-N 2.63Å; L356-V365 HydrophobicContact CD1-CG1 4.04Å; L356-V365 HydrophobicContact CD2-CG1 3.78Å; L356-V365 HydrophobicContact CG-CG1 3.53Å
357	M	98	Very high	97.4	Very high	0 Å²	0	48.8 Å²	48.8	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-61.6	-40.9	175	-66.4	166.6	68.7	0	0	112	V293 L296 S353 L354 F433	V293-M357 HydrophobicContact CG2-CE 4.02Å; L296-M357 HydrophobicContact CD2-CB 4.18Å; L296-M357 HydrophobicContact CD2-CE 4.03Å; S353-M357 WeakPolarHBondContact O-CG 3.24Å; S353-M357 PolarHBondContact O-N 3.23Å; L354-M357 HydrophobicContact CD2-SD 4.11Å; L354-M357 PolarHBondContact O-N 3.19Å; M357-F433 HydrophobicContact CE-CD1 4.24Å; M357-F433 HydrophobicContact CE-CE1 3.69Å
358	N	96.9	Very high	97.4	Very high	12 Å²	12	51.2 Å²	51.2	6%	0.064	26%	0.262	C	S	.	.	H	α-helix	trans	-63.7	-54.5	178.5	168.7	63.5	0	0	0	112.3	K300 L354 F355 T430 F433	K300-N358 PolarHBondContact NZ-O 3.03Å; L354-N358 WeakPolarHBondContact O-CB 3.16Å; L354-N358 PolarHBondContact O-N 2.78Å; F355-N358 PolarHBondContact O-N 3.01Å; N358-T430 WeakPolarHBondContact OD1-CG2 3.21Å; N358-T430 PolarHBondContact OD1-O 3.5Å; N358-F433 HydrophobicContact CB-CB 4.42Å
359	Y	96.2	Very high	97.4	Very high	170 Å²	170	48.8 Å²	48.8	67%	0.667	24%	0.243	S	C	*	.	H	α-helix	trans	-79.8	-21.9	-173	-70.1	-65.2	0	0	0	113.8	F355 L434	F355-Y359 WeakPolarHBondContact O-CD2 3.35Å; F355-Y359 PolarHBondContact O-N 2.84Å; Y359-L434 HydrophobicContact CE2-CD1 4.38Å
360	S	95.2	Very high	97.3	Very high	22 Å²	22	46.4 Å²	46.4	15%	0.154	23%	0.228	C	C	.	.			trans	-71.9	146.7	175.6	-175.6	0	0	0	0	111.9	K300 L356 S362 V365	K300-S360 WeakPolarHBondContact CE-O 3.5Å; K300-S360 PolarHBondContact NZ-O 3.35Å; L356-S360 WeakPolarHBondContact O-CB 3.45Å; L356-S360 PolarHBondContact O-N 2.63Å; S360-S362 PolarHBondContact OG-N 3.27Å; S360-V365 WeakPolarHBondContact OG-CB 3.46Å
361	R	93.9	Very high	97.3	Very high	231 Å²	231	48.6 Å²	48.6	87%	0.872	24%	0.239	S	C	*	.			trans	-96.8	-9.4	168	-63.1	-177	-177.6	173.2	-0.2	112.7
362	S	94.9	Very high	97.3	Very high	48 Å²	48	52.6 Å²	52.6	34%	0.336	26%	0.26	S	S	.	.			trans	-89.5	124.6	-176.7	175.1	0	0	0	0	111.1	S360 W364 V365 C366	S360-S362 PolarHBondContact OG-N 3.27Å; S362-W364 PolarHBondContact O-N 3.4Å; S362-W364 PolarHBondContact OG-N 2.88Å; S362-V365 PolarHBondContact O-N 3.27Å; S362-C366 PolarHBondContact O-N 3.42Å; S362-C366 VanDerWaalsContact O-N 3.15Å; S362-C366 PolarHBondContact O-SG 3.04Å; S362-C366 VanDerWaalsContact O-SG 3.35Å
363	I	95.8	Very high	97.3	Very high	24 Å²	24	50.7 Å²	50.7	12%	0.123	24%	0.24	C	C	.	.	H	α-helix	trans	-59.5	-34.3	172.7	-173.4	62.2	0	0	0	112	W297 A301 V365 C366 Y367	W297-I363 HydrophobicContact CB-CD1 3.65Å; W297-I363 HydrophobicContact CG-CD1 3.68Å; A301-I363 HydrophobicContact CB-CB 3.8Å; A301-I363 HydrophobicContact CB-CD1 4.41Å; A301-I363 HydrophobicContact CB-CG1 4.04Å; A301-I363 HydrophobicContact CB-CG2 4.05Å; I363-V365 VanDerWaalsContact C-N 3.33Å; I363-V365 PolarHBondContact O-N 2.86Å; I363-C366 HydrophobicContact CD1-CB 4.3Å; I363-C366 CarbonylContact O-C 3.55Å; I363-C366 WeakPolarHBondContact O-CA 3.42Å; I363-C366 VanDerWaalsContact O-CB 3.32Å; I363-C366 WeakPolarHBondContact O-CB 3.4Å; I363-C366 PolarHBondContact O-N 3.49Å; I363-Y367 HydrophobicContact CD1-CD1 4.18Å; I363-Y367 HydrophobicContact CD1-CE1 3.73Å; I363-Y367 HydrophobicContact CD1-CE2 4.44Å; I363-Y367 HydrophobicContact CG1-CD1 4.3Å; I363-Y367 HydrophobicContact CG1-CD2 4.14Å; I363-Y367 HydrophobicContact CG1-CE1 3.85Å; I363-Y367 HydrophobicContact CG1-CE2 3.64Å; I363-Y367 HydrophobicContact CG1-CG 4.46Å; I363-Y367 VanDerWaalsContact CG1-CZ 3.5Å; I363-Y367 PolarHBondContact O-N 3.12Å
364	W	97.1	Very high	97.2	Very high	159 Å²	159	51.4 Å²	51.4	60%	0.602	24%	0.242	S	C	*	.	H	α-helix	trans	-62.7	-39	177.1	-65.6	105.9	0	0	0	112.8	Y309 S362 C366 Y367 A368	Y309-W364 AromaticContact CD2-CH2 3.62Å; Y309-W364 HydrophobicContact CD2-CH2 3.62Å; Y309-W364 AromaticContact CD2-CZ2 3.96Å; Y309-W364 HydrophobicContact CD2-CZ2 3.96Å; Y309-W364 HydrophobicContact CD2-CZ3 4.4Å; Y309-W364 AromaticContact CE2-CH2 3.73Å; Y309-W364 HydrophobicContact CE2-CH2 3.73Å; Y309-W364 AromaticContact CE2-CZ2 3.78Å; Y309-W364 HydrophobicContact CE2-CZ2 3.78Å; Y309-W364 HydrophobicContact CG-CH2 4.33Å; S362-W364 PolarHBondContact O-N 3.4Å; S362-W364 PolarHBondContact OG-N 2.88Å; W364-C366 VanDerWaalsContact C-N 3.3Å; W364-Y367 HydrophobicContact CE3-CD2 4.18Å; W364-Y367 PolarHBondContact O-N 3.23Å; W364-A368 WeakPolarHBondContact O-CB 3.26Å; W364-A368 PolarHBondContact O-N 2.89Å
365	V	97.3	Very high	97.1	Very high	44 Å²	44	53 Å²	53	27%	0.267	25%	0.253	S	S	.	.	H	α-helix	trans	-67.8	-36.4	173.4	176.3	0	0	0	0	110.2	L356 S360 S362 I363 A368 G369	L356-V365 HydrophobicContact CD1-CG1 4.04Å; L356-V365 HydrophobicContact CD2-CG1 3.78Å; L356-V365 HydrophobicContact CG-CG1 3.53Å; S360-V365 WeakPolarHBondContact OG-CB 3.46Å; S362-V365 PolarHBondContact O-N 3.27Å; I363-V365 VanDerWaalsContact C-N 3.33Å; I363-V365 PolarHBondContact O-N 2.86Å; V365-A368 PolarHBondContact O-N 3.25Å; V365-G369 PolarHBondContact O-N 2.98Å
366	C	97.6	Very high	97.1	Very high	0 Å²	0	50.4 Å²	50.4	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-64.5	-42.3	175.6	-61.4	0	0	0	0	112	S362 I363 W364 G369 Y370	S362-C366 PolarHBondContact O-N 3.42Å; S362-C366 VanDerWaalsContact O-N 3.15Å; S362-C366 PolarHBondContact O-SG 3.04Å; S362-C366 VanDerWaalsContact O-SG 3.35Å; I363-C366 HydrophobicContact CD1-CB 4.3Å; I363-C366 CarbonylContact O-C 3.55Å; I363-C366 WeakPolarHBondContact O-CA 3.42Å; I363-C366 VanDerWaalsContact O-CB 3.32Å; I363-C366 WeakPolarHBondContact O-CB 3.4Å; I363-C366 PolarHBondContact O-N 3.49Å; W364-C366 VanDerWaalsContact C-N 3.3Å; C366-G369 PolarHBondContact O-N 2.64Å; C366-Y370 WeakPolarHBondContact O-CB 3.17Å; C366-Y370 PolarHBondContact O-N 2.84Å
367	Y	98.2	Very high	97.1	Very high	7 Å²	7	47 Å²	47	3%	0.027	22%	0.224	C	C	.	.	H	α-helix	trans	-62.4	-49.3	174	-67.5	-26.6	0	0	0	111.7	W297 Y309 N310 V313 I363 W364 G369 Y370 L371	W297-Y367 HydrophobicContact CD2-CD1 4.08Å; W297-Y367 AromaticContact CD2-CE1 3.61Å; W297-Y367 HydrophobicContact CD2-CE1 3.61Å; W297-Y367 AromaticContact CE2-CD1 3.59Å; W297-Y367 AromaticContact CE2-CE1 3.64Å; W297-Y367 AromaticContact CE3-CE1 4Å; W297-Y367 HydrophobicContact CE3-CE1 4Å; W297-Y367 HydrophobicContact CG-CD1 4.44Å; W297-Y367 AromaticContact CG-CE1 3.94Å; W297-Y367 HydrophobicContact CG-CE1 3.94Å; W297-Y367 HydrophobicContact CH2-CD1 4.49Å; W297-Y367 HydrophobicContact CH2-CE1 4.44Å; W297-Y367 AromaticContact CZ2-CD1 3.84Å; W297-Y367 HydrophobicContact CZ2-CD1 3.84Å; W297-Y367 HydrophobicContact CZ2-CE1 4.08Å; W297-Y367 HydrophobicContact CZ3-CE1 4.39Å; W297-Y367 AromaticContact NE1-CD1 3.71Å; W297-Y367 AromaticContact NE1-CE1 3.96Å; Y309-Y367 PolarHBondContact N-OH 3.37Å; N310-Y367 PolarHBondContact OD1-OH 2.96Å; V313-Y367 HydrophobicContact CB-CD1 4.18Å; V313-Y367 HydrophobicContact CB-CE1 4.46Å; V313-Y367 HydrophobicContact CB-CG 4.37Å; V313-Y367 HydrophobicContact CG1-CD1 3.9Å; V313-Y367 HydrophobicContact CG1-CG 4.2Å; V313-Y367 HydrophobicContact CG2-CD1 3.61Å; V313-Y367 HydrophobicContact CG2-CD2 3.55Å; V313-Y367 HydrophobicContact CG2-CE1 3.93Å; V313-Y367 HydrophobicContact CG2-CE2 3.89Å; V313-Y367 HydrophobicContact CG2-CG 3.4Å; I363-Y367 HydrophobicContact CD1-CD1 4.18Å; I363-Y367 HydrophobicContact CD1-CE1 3.73Å; I363-Y367 HydrophobicContact CD1-CE2 4.44Å; I363-Y367 HydrophobicContact CG1-CD1 4.3Å; I363-Y367 HydrophobicContact CG1-CD2 4.14Å; I363-Y367 HydrophobicContact CG1-CE1 3.85Å; I363-Y367 HydrophobicContact CG1-CE2 3.64Å; I363-Y367 HydrophobicContact CG1-CG 4.46Å; I363-Y367 VanDerWaalsContact CG1-CZ 3.5Å; I363-Y367 PolarHBondContact O-N 3.12Å; W364-Y367 HydrophobicContact CE3-CD2 4.18Å; W364-Y367 PolarHBondContact O-N 3.23Å; Y367-G369 VanDerWaalsContact C-N 3.33Å; Y367-G369 PolarHBondContact O-N 2.87Å; Y367-Y370 WeakPolarHBondContact O-CB 3.39Å; Y367-Y370 PolarHBondContact O-N 3.4Å; Y367-L371 WeakPolarHBondContact O-CG 3.47Å; Y367-L371 PolarHBondContact O-N 3.19Å
368	A	98.1	Very high	97	Very high	50 Å²	50	47.9 Å²	47.9	41%	0.413	23%	0.229	S	C	.	.	H	α-helix	trans	-59.6	-42.8	177.5	0	0	0	0	0	112.3	W364 V365 L371 L372	W364-A368 WeakPolarHBondContact O-CB 3.26Å; W364-A368 PolarHBondContact O-N 2.89Å; V365-A368 PolarHBondContact O-N 3.25Å; A368-L371 PolarHBondContact O-N 3.38Å; A368-L372 PolarHBondContact O-N 2.94Å; A368-L372 VanDerWaalsContact O-N 3.11Å
369	G	98.2	Very high	97	Very high	0 Å²	0	48.2 Å²	48.2	0%	0	23%	0.231	C	C	.	.	H	α-helix	trans	-60.5	-44.4	174.5	0	0	0	0	0	112.3	V365 C366 Y367 L371 L372 V373	V365-G369 PolarHBondContact O-N 2.98Å; C366-G369 PolarHBondContact O-N 2.64Å; Y367-G369 VanDerWaalsContact C-N 3.33Å; Y367-G369 PolarHBondContact O-N 2.87Å; G369-L371 PolarHBondContact O-N 3.35Å; G369-L372 WeakPolarHBondContact O-CB 3.36Å; G369-L372 PolarHBondContact O-N 3.47Å; G369-V373 WeakPolarHBondContact O-CG2 3.37Å; G369-V373 PolarHBondContact O-N 3.16Å
370	Y	98.3	Very high	96.9	Very high	2 Å²	2	40.2 Å²	40.2	1%	0.008	20%	0.199	C	C	.	.	H	α-helix	trans	-61.8	-41.9	176	176.2	-110.7	0	0	0	112.8	L290 V293 W297 V313 E314 A317 C366 Y367 L372 V373 K374	L290-Y370 HydrophobicContact CD2-CE2 3.97Å; V293-Y370 HydrophobicContact CB-CD2 4.49Å; V293-Y370 HydrophobicContact CG1-CD2 4.43Å; V293-Y370 HydrophobicContact CG1-CE2 4.09Å; V293-Y370 HydrophobicContact CG2-CD2 3.85Å; V293-Y370 HydrophobicContact CG2-CE2 4.35Å; V293-Y370 HydrophobicContact CG2-CG 4.3Å; W297-Y370 AromaticContact CH2-CD1 3.88Å; W297-Y370 HydrophobicContact CH2-CD1 3.88Å; W297-Y370 AromaticContact CH2-CE1 3.92Å; W297-Y370 HydrophobicContact CH2-CE1 3.92Å; W297-Y370 HydrophobicContact CH2-CG 4.34Å; W297-Y370 AromaticContact CZ2-CD1 3.65Å; W297-Y370 HydrophobicContact CZ2-CD1 3.65Å; W297-Y370 HydrophobicContact CZ2-CD2 4.37Å; W297-Y370 HydrophobicContact CZ2-CE1 4.15Å; W297-Y370 AromaticContact CZ2-CG 3.74Å; W297-Y370 HydrophobicContact CZ2-CG 3.74Å; V313-Y370 HydrophobicContact CG1-CD1 3.72Å; V313-Y370 HydrophobicContact CG1-CE1 4.24Å; E314-Y370 PolarHBondContact OE1-OH 3.21Å; E314-Y370 VanDerWaalsContact OE2-CE1 3.29Å; E314-Y370 WeakPolarHBondContact OE2-CE1 3.3Å; E314-Y370 PolarHBondContact OE2-OH 3.32Å; A317-Y370 HydrophobicContact CB-CD1 4.14Å; A317-Y370 HydrophobicContact CB-CE1 3.67Å; C366-Y370 WeakPolarHBondContact O-CB 3.17Å; C366-Y370 PolarHBondContact O-N 2.84Å; Y367-Y370 WeakPolarHBondContact O-CB 3.39Å; Y367-Y370 PolarHBondContact O-N 3.4Å; Y370-L372 VanDerWaalsContact C-N 3.3Å; Y370-L372 PolarHBondContact O-N 3.44Å; Y370-V373 PolarHBondContact O-N 3.24Å; Y370-K374 PolarHBondContact O-N 3.38Å
371	L	98.3	Very high	97	Very high	47 Å²	47	40.3 Å²	40.3	25%	0.246	20%	0.198	C	C	.	.	H	α-helix	trans	-58.6	-42.4	175.1	-66.2	-178.2	0	0	0	111.9	V313 I316 A317 Y367 A368 G369 S375	V313-L371 HydrophobicContact CG1-CD2 4.29Å; I316-L371 HydrophobicContact CB-CD2 4.11Å; I316-L371 HydrophobicContact CG2-CD1 3.95Å; I316-L371 HydrophobicContact CG2-CD2 3.83Å; A317-L371 HydrophobicContact CB-CD2 3.51Å; Y367-L371 WeakPolarHBondContact O-CG 3.47Å; Y367-L371 PolarHBondContact O-N 3.19Å; A368-L371 PolarHBondContact O-N 3.38Å; G369-L371 PolarHBondContact O-N 3.35Å; L371-S375 VanDerWaalsContact O-CB 3.29Å; L371-S375 WeakPolarHBondContact O-CB 3.39Å; L371-S375 PolarHBondContact O-N 3.12Å; L371-S375 PolarHBondContact O-OG 3.49Å
372	L	97.9	Very high	97	Very high	88 Å²	88	31.3 Å²	31.3	46%	0.461	17%	0.168	S	C	.	.	H	α-helix	trans	-65.3	-43.8	176	-72.3	173.1	0	0	0	111.8	S353 A368 G369 Y370 S376	S353-L372 WeakPolarHBondContact OG-CB 3.49Å; A368-L372 PolarHBondContact O-N 2.94Å; A368-L372 VanDerWaalsContact O-N 3.11Å; G369-L372 WeakPolarHBondContact O-CB 3.36Å; G369-L372 PolarHBondContact O-N 3.47Å; Y370-L372 VanDerWaalsContact C-N 3.3Å; Y370-L372 PolarHBondContact O-N 3.44Å; L372-S376 WeakPolarHBondContact O-CB 3.47Å; L372-S376 PolarHBondContact O-N 2.94Å; L372-S376 PolarHBondContact O-OG 3.13Å
373	V	98.3	Very high	96.8	Very high	0 Å²	0	29.1 Å²	29.1	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-59.6	-53.6	176.9	170	0	0	0	0	110.7	Y286 I289 I350 L354 G369 Y370 S375 S376 Y377	Y286-V373 HydrophobicContact CD2-CG1 4.27Å; Y286-V373 HydrophobicContact CE2-CG1 4.38Å; I289-V373 HydrophobicContact CD1-CG1 3.94Å; I289-V373 HydrophobicContact CG2-CG1 4.34Å; I350-V373 HydrophobicContact CG2-CG1 4.26Å; I350-V373 HydrophobicContact CG2-CG2 4.22Å; L354-V373 HydrophobicContact CD2-CG2 4.23Å; L354-V373 HydrophobicContact CG-CG2 4.24Å; G369-V373 WeakPolarHBondContact O-CG2 3.37Å; G369-V373 PolarHBondContact O-N 3.16Å; Y370-V373 PolarHBondContact O-N 3.24Å; V373-S375 PolarHBondContact O-N 3.35Å; V373-S376 PolarHBondContact O-N 3.32Å; V373-Y377 WeakPolarHBondContact O-CB 3.27Å; V373-Y377 PolarHBondContact O-N 3.1Å
374	K	97.4	Very high	96.7	Very high	21 Å²	21	28 Å²	28	9%	0.091	15%	0.147	C	C	.	.	H	α-helix	trans	-63.1	-42.6	-176.5	-170.9	166.4	-164.9	-172	0	112	Y286 E314 A317 T318 Y370 S378	Y286-K374 WeakPolarHBondContact OH-CG 3.47Å; E314-K374 IonicContact OE1-NZ 2.59Å; E314-K374 PolarHBondContact OE1-NZ 2.86Å; A317-K374 HydrophobicContact CB-CB 4.27Å; A317-K374 HydrophobicContact CB-CD 3.4Å; A317-K374 HydrophobicContact CB-CG 4.28Å; T318-K374 PolarHBondContact OG1-NZ 3.47Å; Y370-K374 PolarHBondContact O-N 3.38Å; K374-S378 VanDerWaalsContact O-CB 3.3Å; K374-S378 WeakPolarHBondContact O-CB 3.42Å; K374-S378 PolarHBondContact O-N 2.97Å; K374-S378 PolarHBondContact O-OG 3.37Å
375	S	97.1	Very high	96.5	Very high	33 Å²	33	22.2 Å²	22.2	23%	0.231	13%	0.13	C	C	.	.	H	α-helix	trans	-67.4	-43.3	178.6	-54.4	0	0	0	0	111.9	A324 L371 V373 S378 F379	A324-S375 WeakPolarHBondContact CB-O 3.21Å; L371-S375 VanDerWaalsContact O-CB 3.29Å; L371-S375 WeakPolarHBondContact O-CB 3.39Å; L371-S375 PolarHBondContact O-N 3.12Å; L371-S375 PolarHBondContact O-OG 3.49Å; V373-S375 PolarHBondContact O-N 3.35Å; S375-S378 PolarHBondContact O-N 2.86Å; S375-F379 WeakPolarHBondContact O-CB 3.42Å; S375-F379 PolarHBondContact O-N 3.24Å
376	S	97.1	Very high	96.1	Very high	6 Å²	6	25.4 Å²	25.4	4%	0.042	14%	0.14	C	C	.	.	H	α-helix	trans	-66.5	-43.1	179.1	-59	0	0	0	0	112	L372 V373 F379 L380	L372-S376 WeakPolarHBondContact O-CB 3.47Å; L372-S376 PolarHBondContact O-N 2.94Å; L372-S376 PolarHBondContact O-OG 3.13Å; V373-S376 PolarHBondContact O-N 3.32Å; S376-F379 PolarHBondContact O-N 3.46Å; S376-L380 WeakPolarHBondContact O-CG 3.46Å; S376-L380 PolarHBondContact O-N 3.06Å
377	Y	98	Very high	95.7	Very high	23 Å²	23	25.8 Å²	25.8	9%	0.09	14%	0.142	C	C	.	.	H	α-helix	trans	-62.1	-48.7	174.9	174.6	-98.3	0	0	0	111	A282 T283 Y286 V373 F379 L380 I381	A282-Y377 HydrophobicContact CB-CE2 4.29Å; T283-Y377 PolarHBondContact OG1-OH 3.28Å; Y286-Y377 AromaticContact CD1-CD1 3.49Å; Y286-Y377 HydrophobicContact CD1-CD1 3.49Å; Y286-Y377 VanDerWaalsContact CD1-CD1 3.49Å; Y286-Y377 HydrophobicContact CD1-CD2 4.28Å; Y286-Y377 AromaticContact CD1-CE1 3.26Å; Y286-Y377 HydrophobicContact CD1-CE1 3.26Å; Y286-Y377 HydrophobicContact CD1-CE2 4.1Å; Y286-Y377 HydrophobicContact CD1-CG 4.01Å; Y286-Y377 AromaticContact CD1-CZ 3.59Å; Y286-Y377 AromaticContact CD2-CD1 3.81Å; Y286-Y377 HydrophobicContact CD2-CD1 3.81Å; Y286-Y377 HydrophobicContact CD2-CD2 4.13Å; Y286-Y377 HydrophobicContact CD2-CE1 4.41Å; Y286-Y377 AromaticContact CD2-CG 3.65Å; Y286-Y377 HydrophobicContact CD2-CG 3.65Å; Y286-Y377 AromaticContact CE1-CD1 3.5Å; Y286-Y377 HydrophobicContact CE1-CD1 3.5Å; Y286-Y377 VanDerWaalsContact CE1-CD1 3.5Å; Y286-Y377 AromaticContact CE1-CE1 3.45Å; Y286-Y377 HydrophobicContact CE1-CE1 3.45Å; Y286-Y377 VanDerWaalsContact CE1-CE1 3.45Å; Y286-Y377 HydrophobicContact CE1-CG 4.32Å; Y286-Y377 AromaticContact CE2-CD1 3.86Å; Y286-Y377 HydrophobicContact CE2-CD1 3.86Å; Y286-Y377 HydrophobicContact CE2-CG 4.04Å; Y286-Y377 AromaticContact CG-CD1 3.64Å; Y286-Y377 HydrophobicContact CG-CD1 3.64Å; Y286-Y377 AromaticContact CG-CD2 3.79Å; Y286-Y377 HydrophobicContact CG-CD2 3.79Å; Y286-Y377 AromaticContact CG-CE1 3.78Å; Y286-Y377 HydrophobicContact CG-CE1 3.78Å; Y286-Y377 AromaticContact CG-CE2 3.92Å; Y286-Y377 HydrophobicContact CG-CE2 3.92Å; Y286-Y377 AromaticContact CG-CG 3.64Å; Y286-Y377 HydrophobicContact CG-CG 3.64Å; Y286-Y377 AromaticContact CG-CZ 3.91Å; Y286-Y377 AromaticContact CZ-CD1 3.7Å; V373-Y377 WeakPolarHBondContact O-CB 3.27Å; V373-Y377 PolarHBondContact O-N 3.1Å; Y377-F379 VanDerWaalsContact C-N 3.29Å; Y377-F379 PolarHBondContact O-N 3.03Å; Y377-L380 PolarHBondContact O-N 3.49Å; Y377-I381 HydrophobicContact CD1-CG2 4.38Å; Y377-I381 HydrophobicContact CE1-CB 4.31Å; Y377-I381 HydrophobicContact CE1-CG2 4.1Å; Y377-I381 HydrophobicContact CE2-CB 4.42Å; Y377-I381 WeakPolarHBondContact O-CB 3.31Å; Y377-I381 VanDerWaalsContact O-CG2 3.27Å; Y377-I381 WeakPolarHBondContact O-CG2 3.46Å; Y377-I381 PolarHBondContact O-N 2.81Å
378	S	95.9	Very high	95.3	Very high	18 Å²	18	25.5 Å²	25.5	13%	0.126	14%	0.141	C	C	.	.	H	α-helix	trans	-59	-39.9	179.5	-57.8	0	0	0	0	112.3	G321 S325 K374 S375 I381 T382	G321-S378 WeakPolarHBondContact CA-OG 3.33Å; G321-S378 WeakPolarHBondContact O-CB 3.48Å; S325-S378 PolarHBondContact OG-O 3.44Å; K374-S378 VanDerWaalsContact O-CB 3.3Å; K374-S378 WeakPolarHBondContact O-CB 3.42Å; K374-S378 PolarHBondContact O-N 2.97Å; K374-S378 PolarHBondContact O-OG 3.37Å; S375-S378 PolarHBondContact O-N 2.86Å; S378-I381 WeakPolarHBondContact O-CG2 3.24Å; S378-T382 WeakPolarHBondContact O-CB 3.12Å; S378-T382 PolarHBondContact O-N 3.38Å; S378-T382 PolarHBondContact O-OG1 2.91Å
379	F	95.5	Very high	94.7	Very high	20 Å²	20	24.9 Å²	24.9	9%	0.088	14%	0.135	C	C	.	.	H	α-helix	trans	-60.9	-54.8	173.7	-176.8	-103.8	0	0	0	111.9	A324 V328 L331 W335 F346 S375 S376 Y377 T382 I383	A324-F379 HydrophobicContact CB-CB 4.12Å; V328-F379 HydrophobicContact CG2-CD2 3.58Å; V328-F379 HydrophobicContact CG2-CE2 3.61Å; V328-F379 HydrophobicContact CG2-CG 4.37Å; V328-F379 HydrophobicContact CG2-CZ 4.43Å; L331-F379 HydrophobicContact CD1-CE2 3.58Å; L331-F379 HydrophobicContact CD1-CZ 3.45Å; L331-F379 VanDerWaalsContact CD1-CZ 3.45Å; W335-F379 HydrophobicContact CH2-CZ 4.25Å; F346-F379 HydrophobicContact CD1-CD1 4.43Å; F346-F379 HydrophobicContact CD2-CD1 4.07Å; F346-F379 HydrophobicContact CD2-CE1 4.02Å; F346-F379 HydrophobicContact CE1-CD1 4.2Å; F346-F379 AromaticContact CE2-CD1 3.83Å; F346-F379 HydrophobicContact CE2-CD1 3.83Å; F346-F379 AromaticContact CE2-CE1 3.48Å; F346-F379 HydrophobicContact CE2-CE1 3.48Å; F346-F379 VanDerWaalsContact CE2-CE1 3.48Å; F346-F379 HydrophobicContact CE2-CZ 4.39Å; F346-F379 HydrophobicContact CG-CD1 4.36Å; F346-F379 AromaticContact CZ-CD1 3.89Å; F346-F379 HydrophobicContact CZ-CD1 3.89Å; F346-F379 AromaticContact CZ-CE1 3.76Å; F346-F379 HydrophobicContact CZ-CE1 3.76Å; F346-F379 HydrophobicContact CZ-CZ 4.45Å; S375-F379 WeakPolarHBondContact O-CB 3.42Å; S375-F379 PolarHBondContact O-N 3.24Å; S376-F379 PolarHBondContact O-N 3.46Å; Y377-F379 VanDerWaalsContact C-N 3.29Å; Y377-F379 PolarHBondContact O-N 3.03Å; F379-T382 PolarHBondContact O-N 3.2Å; F379-I383 HydrophobicContact CD1-CD1 3.77Å; F379-I383 HydrophobicContact CE1-CD1 3.35Å; F379-I383 HydrophobicContact CE2-CD1 4.3Å; F379-I383 HydrophobicContact CG-CD1 4.39Å; F379-I383 HydrophobicContact CZ-CD1 3.66Å; F379-I383 PolarHBondContact O-N 2.9Å
380	L	95.8	Very high	94.1	Very high	1 Å²	1	29.1 Å²	29.1	1%	0.005	16%	0.161	C	C	.	.	H	α-helix	trans	-67.3	-41.8	-175.7	-72.2	-175.3	0	0	0	113	W278 L343 F346 S376 Y377 T382 I383 A384	W278-L380 HydrophobicContact CH2-CB 3.21Å; W278-L380 HydrophobicContact CH2-CD1 3.97Å; W278-L380 HydrophobicContact CH2-CG 4.27Å; W278-L380 HydrophobicContact CZ2-CB 3.48Å; W278-L380 VanDerWaalsContact CZ2-CB 3.48Å; W278-L380 HydrophobicContact CZ2-CD1 3.28Å; W278-L380 HydrophobicContact CZ2-CG 4.05Å; W278-L380 HydrophobicContact CZ3-CB 4.02Å; L343-L380 HydrophobicContact CD2-CD1 4.44Å; L343-L380 HydrophobicContact CD2-CD2 4.04Å; F346-L380 HydrophobicContact CB-CD1 3.47Å; F346-L380 VanDerWaalsContact CB-CD1 3.47Å; F346-L380 HydrophobicContact CB-CD2 3.81Å; F346-L380 HydrophobicContact CB-CG 3.62Å; F346-L380 HydrophobicContact CD2-CD2 4.07Å; F346-L380 HydrophobicContact CG-CD2 4.19Å; F346-L380 HydrophobicContact CG-CG 4.27Å; S376-L380 WeakPolarHBondContact O-CG 3.46Å; S376-L380 PolarHBondContact O-N 3.06Å; Y377-L380 PolarHBondContact O-N 3.49Å; L380-T382 VanDerWaalsContact C-N 3.25Å; L380-T382 PolarHBondContact O-N 2.9Å; L380-I383 PolarHBondContact O-N 2.86Å; L380-I383 VanDerWaalsContact O-N 3.16Å; L380-A384 WeakPolarHBondContact O-CB 3.45Å; L380-A384 PolarHBondContact O-N 3.34Å
381	I	95.5	Very high	93	Very high	25 Å²	25	34.1 Å²	34.1	13%	0.128	19%	0.188	C	C	.	.	H	α-helix	trans	-64	-34.7	179.2	-164.9	62.7	0	0	0	111.2	W278 W279 Y377 S378 I383 A384 V385	W278-I381 HydrophobicContact CZ3-CD1 4.12Å; W279-I381 HydrophobicContact CB-CD1 4.36Å; W279-I381 HydrophobicContact CD2-CD1 3.83Å; W279-I381 HydrophobicContact CG-CD1 3.71Å; Y377-I381 HydrophobicContact CD1-CG2 4.38Å; Y377-I381 HydrophobicContact CE1-CB 4.31Å; Y377-I381 HydrophobicContact CE1-CG2 4.1Å; Y377-I381 HydrophobicContact CE2-CB 4.42Å; Y377-I381 WeakPolarHBondContact O-CB 3.31Å; Y377-I381 VanDerWaalsContact O-CG2 3.27Å; Y377-I381 WeakPolarHBondContact O-CG2 3.46Å; Y377-I381 PolarHBondContact O-N 2.81Å; S378-I381 WeakPolarHBondContact O-CG2 3.24Å; I381-I383 PolarHBondContact O-N 2.73Å; I381-A384 PolarHBondContact O-N 2.97Å; I381-V385 HydrophobicContact CG1-CG2 4.33Å; I381-V385 WeakPolarHBondContact O-CB 3.38Å; I381-V385 WeakPolarHBondContact O-CG2 3.36Å; I381-V385 PolarHBondContact O-N 3.1Å
382	T	94	Very high	92.2	Very high	41 Å²	41	33.3 Å²	33.3	25%	0.252	18%	0.184	S	C	.	.	H	α-helix	trans	-63.4	-42.8	175.1	-56.5	0	0	0	0	111.2	S325 V328 S378 F379 L380 F386	S325-T382 VanDerWaalsContact CB-OG1 3.3Å; S325-T382 WeakPolarHBondContact CB-OG1 3.3Å; S325-T382 PolarHBondContact OG-OG1 2.93Å; V328-T382 HydrophobicContact CB-CG2 4.09Å; V328-T382 HydrophobicContact CG1-CG2 4.27Å; V328-T382 HydrophobicContact CG2-CG2 4.05Å; S378-T382 WeakPolarHBondContact O-CB 3.12Å; S378-T382 PolarHBondContact O-N 3.38Å; S378-T382 PolarHBondContact O-OG1 2.91Å; F379-T382 PolarHBondContact O-N 3.2Å; L380-T382 VanDerWaalsContact C-N 3.25Å; L380-T382 PolarHBondContact O-N 2.9Å; T382-F386 WeakPolarHBondContact O-CB 3.44Å; T382-F386 PolarHBondContact O-N 3.28Å; T382-F386 VanDerWaalsContact O-N 3.11Å
383	I	92	Very high	91.3	Very high	2 Å²	2	32 Å²	32	1%	0.01	18%	0.182	C	C	.	.	H	α-helix	trans	-66	-47.4	175.5	-63.5	160.5	0	0	0	110.3	W275 V328 W335 F379 L380 I381 V385 F386 Q387	W275-I383 HydrophobicContact CH2-CG2 3.56Å; W275-I383 HydrophobicContact CZ2-CG2 4.44Å; W275-I383 HydrophobicContact CZ3-CG2 3.86Å; V328-I383 HydrophobicContact CB-CG1 4.43Å; V328-I383 HydrophobicContact CG1-CG1 3.63Å; V328-I383 HydrophobicContact CG2-CD1 4.28Å; V328-I383 HydrophobicContact CG2-CG1 3.86Å; W335-I383 HydrophobicContact CD2-CG2 4.08Å; W335-I383 HydrophobicContact CE3-CD1 4.41Å; W335-I383 HydrophobicContact CE3-CG2 3.93Å; W335-I383 HydrophobicContact CH2-CD1 3.36Å; W335-I383 HydrophobicContact CH2-CG1 4.04Å; W335-I383 HydrophobicContact CZ2-CD1 3.97Å; W335-I383 HydrophobicContact CZ2-CG1 4.17Å; W335-I383 HydrophobicContact CZ3-CD1 3.62Å; W335-I383 HydrophobicContact CZ3-CG1 4.36Å; W335-I383 HydrophobicContact CZ3-CG2 4.22Å; F379-I383 HydrophobicContact CD1-CD1 3.77Å; F379-I383 HydrophobicContact CE1-CD1 3.35Å; F379-I383 HydrophobicContact CE2-CD1 4.3Å; F379-I383 HydrophobicContact CG-CD1 4.39Å; F379-I383 HydrophobicContact CZ-CD1 3.66Å; F379-I383 PolarHBondContact O-N 2.9Å; L380-I383 PolarHBondContact O-N 2.86Å; L380-I383 VanDerWaalsContact O-N 3.16Å; I381-I383 PolarHBondContact O-N 2.73Å; I383-V385 PolarHBondContact O-N 3.36Å; I383-F386 WeakPolarHBondContact O-CB 3.31Å; I383-F386 PolarHBondContact O-N 2.82Å; I383-F386 VanDerWaalsContact O-N 3.15Å; I383-Q387 HydrophobicContact CG2-CG 4.04Å; I383-Q387 WeakPolarHBondContact O-CB 3.39Å; I383-Q387 VanDerWaalsContact O-CG 3.28Å; I383-Q387 WeakPolarHBondContact O-CG 3.47Å; I383-Q387 PolarHBondContact O-N 2.96Å
384	A	93.6	Very high	90.1	Very high	0 Å²	0	37.2 Å²	37.2	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-59.2	-47.4	-178.8	0	0	0	0	0	111.8	W275 W278 L380 I381 F386 Q387 I388	W275-A384 VanDerWaalsContact CE3-CA 3.47Å; W275-A384 HydrophobicContact CE3-CB 3.65Å; W275-A384 HydrophobicContact CZ3-CB 4.05Å; W278-A384 HydrophobicContact CE3-CB 3.73Å; W278-A384 HydrophobicContact CZ3-CB 3.74Å; L380-A384 WeakPolarHBondContact O-CB 3.45Å; L380-A384 PolarHBondContact O-N 3.34Å; I381-A384 PolarHBondContact O-N 2.97Å; A384-F386 VanDerWaalsContact C-N 3.32Å; A384-F386 PolarHBondContact O-N 3.19Å; A384-Q387 PolarHBondContact O-N 3.27Å; A384-I388 WeakPolarHBondContact O-CB 3.27Å; A384-I388 WeakPolarHBondContact O-CD1 3.23Å; A384-I388 VanDerWaalsContact O-CG1 3.31Å; A384-I388 WeakPolarHBondContact O-CG1 3.42Å; A384-I388 PolarHBondContact O-N 2.6Å
385	V	92.1	Very high	88.9	Confident	39 Å²	39	43.5 Å²	43.5	24%	0.236	24%	0.239	C	C	.	.	H	α-helix	trans	-56.7	-46.9	174.8	168.2	0	0	0	0	111	W279 I381 I383 I388 A389 Y397	W279-V385 HydrophobicContact CE3-CG2 4.27Å; W279-V385 HydrophobicContact CH2-CG2 3.49Å; W279-V385 VanDerWaalsContact CH2-CG2 3.49Å; W279-V385 HydrophobicContact CZ2-CG2 4.11Å; W279-V385 HydrophobicContact CZ3-CB 4.39Å; W279-V385 HydrophobicContact CZ3-CG2 3.61Å; I381-V385 HydrophobicContact CG1-CG2 4.33Å; I381-V385 WeakPolarHBondContact O-CB 3.38Å; I381-V385 WeakPolarHBondContact O-CG2 3.36Å; I381-V385 PolarHBondContact O-N 3.1Å; I383-V385 PolarHBondContact O-N 3.36Å; V385-I388 PolarHBondContact O-N 2.96Å; V385-A389 VanDerWaalsContact O-CB 3.23Å; V385-A389 WeakPolarHBondContact O-CB 3.33Å; V385-A389 PolarHBondContact O-N 3.35Å; V385-Y397 HydrophobicContact CG1-CE2 4.28Å; V385-Y397 VanDerWaalsContact CG1-OH 3.24Å; V385-Y397 WeakPolarHBondContact CG1-OH 3.01Å
386	F	88.9	Confident	88.1	Confident	110 Å²	110	45.6 Å²	45.6	48%	0.482	24%	0.242	S	C	.	.	H	α-helix	trans	-62.4	-44.3	178.5	174.2	-101.4	0	0	0	112.3	T382 I383 A384 I388 A389 V390	T382-F386 WeakPolarHBondContact O-CB 3.44Å; T382-F386 PolarHBondContact O-N 3.28Å; T382-F386 VanDerWaalsContact O-N 3.11Å; I383-F386 WeakPolarHBondContact O-CB 3.31Å; I383-F386 PolarHBondContact O-N 2.82Å; I383-F386 VanDerWaalsContact O-N 3.15Å; A384-F386 VanDerWaalsContact C-N 3.32Å; A384-F386 PolarHBondContact O-N 3.19Å; F386-I388 VanDerWaalsContact C-N 3.32Å; F386-I388 PolarHBondContact O-N 3.3Å; F386-A389 PolarHBondContact O-N 2.91Å; F386-V390 PolarHBondContact O-N 2.83Å
387	Q	89.8	Confident	87.4	Confident	9 Å²	9	47.9 Å²	47.9	4%	0.042	25%	0.25	C	S	.	.	H	α-helix	trans	-67.6	-31.1	-179.1	-71.8	-58.4	-32.3	0	0	113.4	H271 W275 I383 A384	H271-Q387 PolarHBondContact CE1-OE1 3.41Å; W275-Q387 HydrophobicContact CD2-CB 3.84Å; W275-Q387 HydrophobicContact CD2-CG 4.25Å; W275-Q387 HydrophobicContact CE3-CB 4.39Å; W275-Q387 HydrophobicContact CG-CB 4.02Å; W275-Q387 HydrophobicContact CH2-CG 4.11Å; W275-Q387 HydrophobicContact CZ2-CB 4.2Å; W275-Q387 HydrophobicContact CZ2-CG 3.69Å; I383-Q387 HydrophobicContact CG2-CG 4.04Å; I383-Q387 WeakPolarHBondContact O-CB 3.39Å; I383-Q387 VanDerWaalsContact O-CG 3.28Å; I383-Q387 WeakPolarHBondContact O-CG 3.47Å; I383-Q387 PolarHBondContact O-N 2.96Å; A384-Q387 PolarHBondContact O-N 3.27Å
388	I	88.6	Confident	86.5	Confident	1 Å²	1	48.9 Å²	48.9	1%	0.005	26%	0.263	C	S	.	.	H	α-helix	trans	-75.3	-43	172.6	-69	161.7	0	0	0	110.1	W275 W279 A384 V385 F386 V390 L392 Y397 V400	W275-I388 HydrophobicContact CB-CD1 3.96Å; W275-I388 HydrophobicContact CB-CG1 3.72Å; W279-I388 HydrophobicContact CE3-CD1 3.44Å; W279-I388 VanDerWaalsContact CE3-CD1 3.44Å; W279-I388 HydrophobicContact CZ3-CD1 3.86Å; A384-I388 WeakPolarHBondContact O-CB 3.27Å; A384-I388 WeakPolarHBondContact O-CD1 3.23Å; A384-I388 VanDerWaalsContact O-CG1 3.31Å; A384-I388 WeakPolarHBondContact O-CG1 3.42Å; A384-I388 PolarHBondContact O-N 2.6Å; V385-I388 PolarHBondContact O-N 2.96Å; F386-I388 VanDerWaalsContact C-N 3.32Å; F386-I388 PolarHBondContact O-N 3.3Å; I388-V390 PolarHBondContact O-N 3.23Å; I388-L392 HydrophobicContact CG2-CD1 3.77Å; I388-L392 WeakPolarHBondContact O-CD1 3.27Å; I388-L392 WeakPolarHBondContact O-CG 3.25Å; I388-Y397 HydrophobicContact CG2-CD2 4.39Å; I388-V400 HydrophobicContact CG2-CB 4.46Å; I388-V400 HydrophobicContact CG2-CG1 3.68Å
389	A	86.5	Confident	85.9	Confident	36 Å²	36	49 Å²	49	30%	0.298	26%	0.262	S	S	.	.	H	α-helix	trans	-67.4	-36.4	-176.1	0	0	0	0	0	113.8	V385 F386 N391 L392 Y397	V385-A389 VanDerWaalsContact O-CB 3.23Å; V385-A389 WeakPolarHBondContact O-CB 3.33Å; V385-A389 PolarHBondContact O-N 3.35Å; F386-A389 PolarHBondContact O-N 2.91Å; A389-N391 PolarHBondContact O-N 2.9Å; A389-L392 PolarHBondContact O-N 3.46Å; A389-L392 VanDerWaalsContact O-N 3.15Å; A389-Y397 HydrophobicContact CB-CD2 3.8Å; A389-Y397 HydrophobicContact CB-CE2 3.85Å
390	V	84.6	Confident	85.5	Confident	89 Å²	89	48 Å²	48	54%	0.539	26%	0.258	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.2	-23.9	-171.4	80.5	0	0	0	0	113.9	F386 I388	F386-V390 PolarHBondContact O-N 2.83Å; I388-V390 PolarHBondContact O-N 3.23Å
391	N	76.3	Confident	85.1	Confident	108 Å²	108	51.3 Å²	51.3	58%	0.578	27%	0.272	S	S	*	.	T	Hydrogen-bonded Turn	trans	-107.9	6.8	-176.4	-65.5	-57.8	0	0	0	113.7	A389	A389-N391 PolarHBondContact O-N 2.9Å
392	L	81.9	Confident	84.8	Confident	30 Å²	30	51.4 Å²	51.4	16%	0.157	28%	0.279	C	S	.	.	S	Bend	trans	-121.2	146	-174.3	-65.6	178.4	0	0	0	111.8	C266 L272 I388 A389 R396 V400	C266-L392 HydrophobicContact CB-CD2 4.43Å; L272-L392 HydrophobicContact CD1-CD1 3.79Å; L272-L392 HydrophobicContact CD1-CD2 3.64Å; L272-L392 HydrophobicContact CD1-CG 3.89Å; I388-L392 HydrophobicContact CG2-CD1 3.77Å; I388-L392 WeakPolarHBondContact O-CD1 3.27Å; I388-L392 WeakPolarHBondContact O-CG 3.25Å; A389-L392 PolarHBondContact O-N 3.46Å; A389-L392 VanDerWaalsContact O-N 3.15Å; L392-R396 HydrophobicContact CB-CB 4.3Å; L392-R396 HydrophobicContact CD2-CB 4.11Å; L392-V400 HydrophobicContact CD1-CB 4.12Å; L392-V400 HydrophobicContact CD1-CG2 3.81Å
393	S	79.3	Confident	84.6	Confident	61 Å²	61	50.9 Å²	50.9	43%	0.427	28%	0.275	S	S	.	.			trans	-66.4	159.4	161.2	64.1	0	0	0	0	110	E395 R396 Y397	S393-E395 VanDerWaalsContact C-N 3.29Å; S393-E395 PolarHBondContact O-N 3.48Å; S393-R396 PolarHBondContact O-N 3.42Å; S393-R396 VanDerWaalsContact O-N 3.16Å; S393-R396 WeakPolarHBondContact OG-CB 3.21Å; S393-R396 WeakPolarHBondContact OG-CG 3.31Å; S393-Y397 WeakPolarHBondContact O-CB 3.24Å; S393-Y397 PolarHBondContact O-N 3.03Å
394	L	72.4	Confident	84.7	Confident	109 Å²	109	50.9 Å²	50.9	57%	0.571	28%	0.275	S	S	*	.	H	α-helix	trans	-58.2	-39.8	-177.7	-170.9	143.9	0	0	0	112.7	Y137 Y397 A398	Y137-L394 HydrophobicContact CD2-CD1 4.44Å; Y137-L394 HydrophobicContact CE2-CD1 4.43Å; L394-Y397 PolarHBondContact O-N 3.47Å; L394-A398 PolarHBondContact O-N 3.15Å; L394-A398 VanDerWaalsContact O-N 3.1Å
395	E	73.1	Confident	84.7	Confident	153 Å²	153	51.8 Å²	51.8	72%	0.715	28%	0.28	S	S	*	.	H	α-helix	trans	-64.3	-45.7	176.6	-65	174.5	-177.9	0	0	111.7	S393 Y397 A398 L399	S393-E395 VanDerWaalsContact C-N 3.29Å; S393-E395 PolarHBondContact O-N 3.48Å; E395-Y397 VanDerWaalsContact C-N 3.35Å; E395-A398 PolarHBondContact O-N 3Å; E395-L399 PolarHBondContact O-N 3.31Å; E395-L399 VanDerWaalsContact O-N 3.17Å
396	R	79.4	Confident	84.9	Confident	76 Å²	76	54 Å²	54	29%	0.287	29%	0.287	S	S	.	.	H	α-helix	trans	-67.9	-34.9	177.7	-71.7	178	174.5	-162.9	-7.8	112.1	D262 E265 L392 S393 L399 V400	D262-R396 IonicContact OD1-CZ 3.62Å; D262-R396 IonicContact OD1-NE 3.7Å; D262-R396 IonicContact OD1-NH2 2.77Å; D262-R396 PolarHBondContact OD1-NH2 2.95Å; E265-R396 IonicContact OE2-CZ 2.79Å; E265-R396 IonicContact OE2-NH1 3.55Å; E265-R396 IonicContact OE2-NH2 2.75Å; E265-R396 PolarHBondContact OE2-NH2 3.44Å; L392-R396 HydrophobicContact CB-CB 4.3Å; L392-R396 HydrophobicContact CD2-CB 4.11Å; S393-R396 PolarHBondContact O-N 3.42Å; S393-R396 VanDerWaalsContact O-N 3.16Å; S393-R396 WeakPolarHBondContact OG-CB 3.21Å; S393-R396 WeakPolarHBondContact OG-CG 3.31Å; R396-L399 WeakPolarHBondContact O-CB 3.38Å; R396-L399 PolarHBondContact O-N 3.35Å; R396-V400 WeakPolarHBondContact O-CG2 3.17Å; R396-V400 PolarHBondContact O-N 3.35Å
397	Y	81.3	Confident	85.3	Confident	55 Å²	55	51.8 Å²	51.8	22%	0.216	28%	0.279	C	S	.	.	H	α-helix	trans	-62.7	-45.7	174.2	171.6	-102.6	0	0	0	111.9	V385 I388 A389 S393 L394 E395 L399 V400 F401	V385-Y397 HydrophobicContact CG1-CE2 4.28Å; V385-Y397 VanDerWaalsContact CG1-OH 3.24Å; V385-Y397 WeakPolarHBondContact CG1-OH 3.01Å; I388-Y397 HydrophobicContact CG2-CD2 4.39Å; A389-Y397 HydrophobicContact CB-CD2 3.8Å; A389-Y397 HydrophobicContact CB-CE2 3.85Å; S393-Y397 WeakPolarHBondContact O-CB 3.24Å; S393-Y397 PolarHBondContact O-N 3.03Å; L394-Y397 PolarHBondContact O-N 3.47Å; E395-Y397 VanDerWaalsContact C-N 3.35Å; Y397-L399 VanDerWaalsContact C-N 3.27Å; Y397-L399 PolarHBondContact O-N 2.79Å; Y397-V400 PolarHBondContact O-N 2.94Å; Y397-F401 VanDerWaalsContact O-CB 3.3Å; Y397-F401 WeakPolarHBondContact O-CB 3.34Å; Y397-F401 PolarHBondContact O-N 2.78Å
398	A	80.3	Confident	85.7	Confident	43 Å²	43	51.4 Å²	51.4	36%	0.355	28%	0.278	S	S	.	.	H	α-helix	trans	-61.8	-37.4	177	0	0	0	0	0	112.1	L394 E395 G402	L394-A398 PolarHBondContact O-N 3.15Å; L394-A398 VanDerWaalsContact O-N 3.1Å; E395-A398 PolarHBondContact O-N 3Å; A398-G402 PolarHBondContact O-N 2.87Å
399	L	82.6	Confident	86.1	Confident	20 Å²	20	51.5 Å²	51.5	11%	0.105	28%	0.278	C	S	.	.	H	α-helix	trans	-62.8	-52.2	174.6	177.5	58.3	0	0	0	112.2	W259 L263 E395 R396 Y397 F401 G402 I403	W259-L399 VanDerWaalsContact CE2-CD1 3.47Å; W259-L399 HydrophobicContact CZ2-CD1 3.54Å; L263-L399 HydrophobicContact CB-CD2 4.33Å; L263-L399 HydrophobicContact CD1-CD2 4.4Å; L263-L399 HydrophobicContact CD1-CG 4.45Å; E395-L399 PolarHBondContact O-N 3.31Å; E395-L399 VanDerWaalsContact O-N 3.17Å; R396-L399 WeakPolarHBondContact O-CB 3.38Å; R396-L399 PolarHBondContact O-N 3.35Å; Y397-L399 VanDerWaalsContact C-N 3.27Å; Y397-L399 PolarHBondContact O-N 2.79Å; L399-F401 VanDerWaalsContact C-N 3.34Å; L399-F401 PolarHBondContact O-N 3.21Å; L399-G402 PolarHBondContact O-N 2.95Å; L399-I403 HydrophobicContact CD1-CD1 3.71Å; L399-I403 HydrophobicContact CD1-CG1 4.35Å; L399-I403 HydrophobicContact CG-CD1 4.11Å; L399-I403 WeakPolarHBondContact O-CG1 3.17Å; L399-I403 PolarHBondContact O-N 3.33Å; L399-I403 VanDerWaalsContact O-N 3.08Å
400	V	88.5	Confident	86.7	Confident	0 Å²	0	52 Å²	52	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-61.1	-44.3	178.9	172.2	0	0	0	0	110.6	C266 Y267 L272 I388 L392 R396 Y397 G402 I403 D404	C266-V400 HydrophobicContact CB-CG2 3.95Å; Y267-V400 HydrophobicContact CE2-CG2 4.22Å; L272-V400 HydrophobicContact CD2-CG1 4.4Å; I388-V400 HydrophobicContact CG2-CB 4.46Å; I388-V400 HydrophobicContact CG2-CG1 3.68Å; L392-V400 HydrophobicContact CD1-CB 4.12Å; L392-V400 HydrophobicContact CD1-CG2 3.81Å; R396-V400 WeakPolarHBondContact O-CG2 3.17Å; R396-V400 PolarHBondContact O-N 3.35Å; Y397-V400 PolarHBondContact O-N 2.94Å; V400-G402 VanDerWaalsContact C-N 3.34Å; V400-G402 PolarHBondContact O-N 3.47Å; V400-I403 PolarHBondContact O-N 3.44Å; V400-D404 WeakPolarHBondContact O-CB 3.22Å; V400-D404 VanDerWaalsContact O-CG 3.26Å; V400-D404 PolarHBondContact O-N 2.9Å
401	F	87.3	Confident	87.3	Confident	70 Å²	70	49.4 Å²	49.4	31%	0.307	26%	0.26	S	S	.	.	H	α-helix	trans	-53.7	-49	174.3	178.9	-78.9	0	0	0	112.2	W279 Y397 L399 I403 T405	W279-F401 AromaticContact CH2-CD2 3.35Å; W279-F401 HydrophobicContact CH2-CD2 3.35Å; W279-F401 AromaticContact CH2-CE2 3.74Å; W279-F401 HydrophobicContact CH2-CE2 3.74Å; W279-F401 HydrophobicContact CH2-CG 4.25Å; W279-F401 AromaticContact CZ2-CD2 3.59Å; W279-F401 HydrophobicContact CZ2-CD2 3.59Å; W279-F401 AromaticContact CZ2-CE2 3.56Å; W279-F401 HydrophobicContact CZ2-CE2 3.56Å; W279-F401 HydrophobicContact CZ2-CG 4.43Å; W279-F401 HydrophobicContact CZ2-CZ 4.44Å; Y397-F401 VanDerWaalsContact O-CB 3.3Å; Y397-F401 WeakPolarHBondContact O-CB 3.34Å; Y397-F401 PolarHBondContact O-N 2.78Å; L399-F401 VanDerWaalsContact C-N 3.34Å; L399-F401 PolarHBondContact O-N 3.21Å; F401-I403 VanDerWaalsContact C-N 3.34Å; F401-I403 PolarHBondContact O-N 3.12Å; F401-T405 WeakPolarHBondContact O-CB 3.29Å; F401-T405 PolarHBondContact O-N 3.26Å; F401-T405 PolarHBondContact O-OG1 3.23Å
402	G	88.3	Confident	88.4	Confident	27 Å²	27	44.2 Å²	44.2	28%	0.278	23%	0.232	S	C	.	.	H	α-helix	trans	-64.2	-39.6	-178	0	0	0	0	0	112.4	A398 L399 V400 F406	A398-G402 PolarHBondContact O-N 2.87Å; L399-G402 PolarHBondContact O-N 2.95Å; V400-G402 VanDerWaalsContact C-N 3.34Å; V400-G402 PolarHBondContact O-N 3.47Å; G402-F406 WeakPolarHBondContact O-CB 3.08Å; G402-F406 PolarHBondContact O-N 3.11Å
403	I	90.5	Very high	89.2	Confident	31 Å²	31	43.9 Å²	43.9	16%	0.159	23%	0.231	C	C	.	.	H	α-helix	trans	-73.3	-44.2	-180	-70	172.7	0	0	0	111.4	W259 L263 Y267 L399 V400 F401 T405 F406 I407	W259-I403 HydrophobicContact CH2-CD1 4.4Å; W259-I403 HydrophobicContact CZ2-CD1 4.2Å; L263-I403 HydrophobicContact CD1-CD1 3.1Å; L263-I403 HydrophobicContact CD2-CD1 3.83Å; L263-I403 HydrophobicContact CG-CD1 4.08Å; Y267-I403 HydrophobicContact CE2-CG2 4.43Å; L399-I403 HydrophobicContact CD1-CD1 3.71Å; L399-I403 HydrophobicContact CD1-CG1 4.35Å; L399-I403 HydrophobicContact CG-CD1 4.11Å; L399-I403 WeakPolarHBondContact O-CG1 3.17Å; L399-I403 PolarHBondContact O-N 3.33Å; L399-I403 VanDerWaalsContact O-N 3.08Å; V400-I403 PolarHBondContact O-N 3.44Å; F401-I403 VanDerWaalsContact C-N 3.34Å; F401-I403 PolarHBondContact O-N 3.12Å; I403-T405 VanDerWaalsContact C-N 3.26Å; I403-T405 PolarHBondContact O-N 2.71Å; I403-F406 PolarHBondContact O-N 2.97Å; I403-F406 VanDerWaalsContact O-N 3.15Å; I403-I407 HydrophobicContact CG2-CD1 3.68Å; I403-I407 HydrophobicContact CG2-CG1 4.27Å; I403-I407 WeakPolarHBondContact O-CB 3.29Å; I403-I407 VanDerWaalsContact O-CG1 3.29Å; I403-I407 WeakPolarHBondContact O-CG1 3.3Å; I403-I407 PolarHBondContact O-N 3.04Å
404	D	94	Very high	90.1	Very high	2 Å²	2	44.9 Å²	44.9	1%	0.011	23%	0.231	C	C	.	.	H	α-helix	trans	-60.2	-40.5	176.2	-70.6	-4.1	0	0	0	110.9	Y267 S276 W279 V400 A408	Y267-D404 PolarHBondContact OH-OD1 3.22Å; S276-D404 WeakPolarHBondContact CA-OD2 3.48Å; S276-D404 WeakPolarHBondContact CB-OD1 3.25Å; S276-D404 VanDerWaalsContact CB-OD2 3.28Å; S276-D404 WeakPolarHBondContact CB-OD2 3.18Å; S276-D404 PolarHBondContact OG-OD2 2.94Å; W279-D404 HydrophobicContact CD2-CB 4.24Å; W279-D404 HydrophobicContact CG-CB 4.31Å; V400-D404 WeakPolarHBondContact O-CB 3.22Å; V400-D404 VanDerWaalsContact O-CG 3.26Å; V400-D404 PolarHBondContact O-N 2.9Å; D404-A408 WeakPolarHBondContact O-CB 3.41Å; D404-A408 PolarHBondContact O-N 3.36Å
405	T	94	Very high	91.3	Very high	18 Å²	18	40.5 Å²	40.5	11%	0.11	21%	0.208	C	C	.	.	H	α-helix	trans	-63	-46.8	174	-57.5	0	0	0	0	111.4	L68 F401 I403 A408 L409	L68-T405 HydrophobicContact CD2-CG2 4.24Å; F401-T405 WeakPolarHBondContact O-CB 3.29Å; F401-T405 PolarHBondContact O-N 3.26Å; F401-T405 PolarHBondContact O-OG1 3.23Å; I403-T405 VanDerWaalsContact C-N 3.26Å; I403-T405 PolarHBondContact O-N 2.71Å; T405-A408 WeakPolarHBondContact O-CB 3.3Å; T405-A408 PolarHBondContact O-N 2.92Å; T405-L409 WeakPolarHBondContact O-CG 3.41Å; T405-L409 PolarHBondContact O-N 3.39Å
406	F	95.1	Very high	92.5	Very high	86 Å²	86	33.2 Å²	33.2	38%	0.377	17%	0.174	S	C	.	.	H	α-helix	trans	-61.7	-45.9	178.1	178.8	-102.3	0	0	0	112	L65 P69 G402 I403 A408 L409 V410	L65-F406 HydrophobicContact CD1-CD2 4.06Å; L65-F406 HydrophobicContact CD1-CE2 3.73Å; L65-F406 HydrophobicContact CD1-CZ 4.44Å; P69-F406 HydrophobicContact CG-CD2 4.26Å; P69-F406 HydrophobicContact CG-CE2 3.91Å; G402-F406 WeakPolarHBondContact O-CB 3.08Å; G402-F406 PolarHBondContact O-N 3.11Å; I403-F406 PolarHBondContact O-N 2.97Å; I403-F406 VanDerWaalsContact O-N 3.15Å; F406-A408 VanDerWaalsContact C-N 3.31Å; F406-A408 PolarHBondContact O-N 3.31Å; F406-L409 PolarHBondContact O-N 3.13Å; F406-V410 HydrophobicContact CD1-CG2 4.24Å; F406-V410 HydrophobicContact CE1-CG2 3.82Å; F406-V410 HydrophobicContact CE2-CG2 4.34Å; F406-V410 HydrophobicContact CZ-CG2 3.87Å; F406-V410 WeakPolarHBondContact O-CG2 3.34Å; F406-V410 PolarHBondContact O-N 3.37Å
407	I	96.7	Very high	93.4	Very high	64 Å²	64	34.4 Å²	34.4	33%	0.328	18%	0.184	S	C	.	.	H	α-helix	trans	-61.2	-41.9	176.5	-66.1	169.9	0	0	0	110.3	A280 I403 L409 V410 I411	A280-I407 HydrophobicContact CB-CB 4.16Å; A280-I407 HydrophobicContact CB-CG2 3.81Å; I403-I407 HydrophobicContact CG2-CD1 3.68Å; I403-I407 HydrophobicContact CG2-CG1 4.27Å; I403-I407 WeakPolarHBondContact O-CB 3.29Å; I403-I407 VanDerWaalsContact O-CG1 3.29Å; I403-I407 WeakPolarHBondContact O-CG1 3.3Å; I403-I407 PolarHBondContact O-N 3.04Å; I407-L409 VanDerWaalsContact C-N 3.33Å; I407-L409 PolarHBondContact O-N 3.39Å; I407-V410 PolarHBondContact O-N 2.96Å; I407-I411 HydrophobicContact CG2-CD1 3.73Å; I407-I411 HydrophobicContact CG2-CG1 4.32Å; I407-I411 VanDerWaalsContact O-CG1 3.31Å; I407-I411 WeakPolarHBondContact O-CG1 3.43Å; I407-I411 PolarHBondContact O-N 3.14Å
408	A	98.2	Very high	94.1	Very high	1 Å²	1	35.7 Å²	35.7	1%	0.008	19%	0.194	C	C	.	.	H	α-helix	trans	-57.4	-45.8	174.8	0	0	0	0	0	111.6	A280 T283 A284 D404 T405 F406 V410 I411 Q412	A280-A408 WeakPolarHBondContact O-CA 3.44Å; A280-A408 WeakPolarHBondContact O-CB 3.39Å; T283-A408 HydrophobicContact CG2-CB 4.02Å; A284-A408 VanDerWaalsContact CB-O 3.25Å; A284-A408 WeakPolarHBondContact CB-O 3.39Å; D404-A408 WeakPolarHBondContact O-CB 3.41Å; D404-A408 PolarHBondContact O-N 3.36Å; T405-A408 WeakPolarHBondContact O-CB 3.3Å; T405-A408 PolarHBondContact O-N 2.92Å; F406-A408 VanDerWaalsContact C-N 3.31Å; F406-A408 PolarHBondContact O-N 3.31Å; A408-V410 PolarHBondContact O-N 3.19Å; A408-I411 PolarHBondContact O-N 3.22Å; A408-Q412 VanDerWaalsContact O-CB 3.22Å; A408-Q412 WeakPolarHBondContact O-CB 3.46Å; A408-Q412 PolarHBondContact O-N 2.96Å
409	L	98	Very high	95	Very high	3 Å²	3	34.2 Å²	34.2	2%	0.016	18%	0.18	C	C	.	.	H	α-helix	trans	-67.5	-34	178.1	-65.9	-170.2	0	0	0	113.1	Y64 L65 L68 T405 F406 I407 T413	Y64-L409 HydrophobicContact CD1-CD1 4.1Å; Y64-L409 HydrophobicContact CD1-CD2 3.68Å; Y64-L409 HydrophobicContact CD2-CD1 3.78Å; Y64-L409 HydrophobicContact CE1-CD1 4.11Å; Y64-L409 HydrophobicContact CE1-CD2 3.64Å; Y64-L409 HydrophobicContact CE2-CD1 3.75Å; Y64-L409 HydrophobicContact CG-CD1 3.94Å; Y64-L409 HydrophobicContact CG-CD2 4.29Å; L65-L409 HydrophobicContact CB-CB 4.31Å; L65-L409 HydrophobicContact CD1-CB 3.77Å; L68-L409 HydrophobicContact CB-CD1 4.2Å; L68-L409 HydrophobicContact CD2-CD1 3.47Å; L68-L409 VanDerWaalsContact CD2-CD1 3.47Å; L68-L409 HydrophobicContact CD2-CG 4.49Å; L68-L409 HydrophobicContact CG-CD1 4.39Å; T405-L409 WeakPolarHBondContact O-CG 3.41Å; T405-L409 PolarHBondContact O-N 3.39Å; F406-L409 PolarHBondContact O-N 3.13Å; I407-L409 VanDerWaalsContact C-N 3.33Å; I407-L409 PolarHBondContact O-N 3.39Å; L409-T413 VanDerWaalsContact O-CB 3.23Å; L409-T413 WeakPolarHBondContact O-CB 3.3Å; L409-T413 PolarHBondContact O-N 2.97Å; L409-T413 PolarHBondContact O-OG1 3.3Å
410	V	98.5	Very high	95.7	Very high	47 Å²	47	33.2 Å²	33.2	29%	0.285	18%	0.175	S	C	.	.	H	α-helix	trans	-64.7	-49.4	173.3	171	0	0	0	0	110.4	L65 F406 I407 A408 Q412 T413 I414	L65-V410 HydrophobicContact CD1-CG2 3.8Å; L65-V410 HydrophobicContact CD2-CG2 4.31Å; F406-V410 HydrophobicContact CD1-CG2 4.24Å; F406-V410 HydrophobicContact CE1-CG2 3.82Å; F406-V410 HydrophobicContact CE2-CG2 4.34Å; F406-V410 HydrophobicContact CZ-CG2 3.87Å; F406-V410 WeakPolarHBondContact O-CG2 3.34Å; F406-V410 PolarHBondContact O-N 3.37Å; I407-V410 PolarHBondContact O-N 2.96Å; A408-V410 PolarHBondContact O-N 3.19Å; V410-Q412 VanDerWaalsContact C-N 3.33Å; V410-Q412 PolarHBondContact O-N 3.36Å; V410-T413 PolarHBondContact O-N 2.93Å; V410-I414 HydrophobicContact CG1-CD1 3.87Å; V410-I414 WeakPolarHBondContact O-CG1 3.43Å; V410-I414 PolarHBondContact O-N 3.47Å
411	I	98.4	Very high	96	Very high	33 Å²	33	33.9 Å²	33.9	17%	0.169	18%	0.178	C	C	.	.	H	α-helix	trans	-60.5	-45.3	177.3	-65.7	165.3	0	0	0	110.2	A280 F281 A284 I407 A408 T413 I414 M415	A280-I411 HydrophobicContact CB-CD1 4.48Å; F281-I411 HydrophobicContact CD1-CD1 3.77Å; F281-I411 HydrophobicContact CD1-CG2 4.35Å; F281-I411 HydrophobicContact CE1-CD1 3.76Å; F281-I411 HydrophobicContact CG-CD1 4.29Å; F281-I411 HydrophobicContact CZ-CD1 4.27Å; A284-I411 HydrophobicContact CB-CB 3.83Å; A284-I411 HydrophobicContact CB-CG2 3.65Å; I407-I411 HydrophobicContact CG2-CD1 3.73Å; I407-I411 HydrophobicContact CG2-CG1 4.32Å; I407-I411 VanDerWaalsContact O-CG1 3.31Å; I407-I411 WeakPolarHBondContact O-CG1 3.43Å; I407-I411 PolarHBondContact O-N 3.14Å; A408-I411 PolarHBondContact O-N 3.22Å; I411-T413 VanDerWaalsContact C-N 3.32Å; I411-T413 PolarHBondContact O-N 2.72Å; I411-I414 PolarHBondContact O-N 3.4Å; I411-M415 WeakPolarHBondContact O-CB 3.41Å; I411-M415 PolarHBondContact O-N 3.06Å
412	Q	98.2	Very high	96.3	Very high	0 Å²	0	34.7 Å²	34.7	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-57.3	-46.5	175.8	-176.5	-172.9	-22.1	0	0	110.9	T61 A284 N287 Q288 A408 V410 M415 T416	T61-Q412 HydrophobicContact CG2-CB 4.49Å; T61-Q412 HydrophobicContact CG2-CG 3.79Å; T61-Q412 PolarHBondContact OG1-NE2 3.29Å; A284-Q412 HydrophobicContact CB-CB 4.12Å; N287-Q412 HydrophobicContact CB-CG 4.4Å; N287-Q412 VanDerWaalsContact CB-OE1 3.25Å; N287-Q412 PolarHBondContact ND2-OE1 3.32Å; Q288-Q412 HydrophobicContact CG-CG 3.94Å; Q288-Q412 PolarHBondContact NE2-O 2.86Å; A408-Q412 VanDerWaalsContact O-CB 3.22Å; A408-Q412 WeakPolarHBondContact O-CB 3.46Å; A408-Q412 PolarHBondContact O-N 2.96Å; V410-Q412 VanDerWaalsContact C-N 3.33Å; V410-Q412 PolarHBondContact O-N 3.36Å; Q412-M415 PolarHBondContact O-N 3.3Å; Q412-T416 PolarHBondContact O-N 3.2Å; Q412-T416 PolarHBondContact O-OG1 2.96Å
413	T	98.3	Very high	96.5	Very high	22 Å²	22	44.1 Å²	44.1	14%	0.135	21%	0.21	C	C	.	.	H	α-helix	trans	-64.3	-44	-179.2	-65.8	0	0	0	0	112.1	Y62 L65 L409 V410 I411 M415 T416 M417	Y62-T413 HydrophobicContact CD1-CG2 3.71Å; Y62-T413 HydrophobicContact CE1-CG2 3.9Å; L65-T413 HydrophobicContact CD2-CG2 3.85Å; L65-T413 WeakPolarHBondContact CD2-OG1 3.37Å; L409-T413 VanDerWaalsContact O-CB 3.23Å; L409-T413 WeakPolarHBondContact O-CB 3.3Å; L409-T413 PolarHBondContact O-N 2.97Å; L409-T413 PolarHBondContact O-OG1 3.3Å; V410-T413 PolarHBondContact O-N 2.93Å; I411-T413 VanDerWaalsContact C-N 3.32Å; I411-T413 PolarHBondContact O-N 2.72Å; T413-M415 VanDerWaalsContact C-N 3.3Å; T413-M415 PolarHBondContact O-N 3.18Å; T413-T416 PolarHBondContact O-N 3.46Å; T413-M417 WeakPolarHBondContact O-CB 3.4Å; T413-M417 PolarHBondContact O-N 3.49Å
414	I	98.3	Very high	96.7	Very high	83 Å²	83	44.3 Å²	44.3	43%	0.426	22%	0.221	S	C	.	.	H	α-helix	trans	-60.8	-43.8	175.1	-67.4	166.5	0	0	0	110	V410 I411 M417 I418	V410-I414 HydrophobicContact CG1-CD1 3.87Å; V410-I414 WeakPolarHBondContact O-CG1 3.43Å; V410-I414 PolarHBondContact O-N 3.47Å; I411-I414 PolarHBondContact O-N 3.4Å; I414-M417 PolarHBondContact O-N 2.95Å; I414-I418 HydrophobicContact CG2-CD1 3.73Å; I414-I418 WeakPolarHBondContact O-CG1 3.48Å; I414-I418 PolarHBondContact O-N 2.86Å
415	M	97.8	Very high	96.8	Very high	17 Å²	17	49.4 Å²	49.4	8%	0.084	25%	0.247	C	C	.	.	H	α-helix	trans	-64.3	-44.8	177.9	-169.5	158.9	69.2	0	0	111.8	Q288 I411 Q412 T413 M417 I418 V419 Y436 Y439	Q288-M415 HydrophobicContact CB-CE 3.77Å; Q288-M415 HydrophobicContact CG-CE 3.29Å; I411-M415 WeakPolarHBondContact O-CB 3.41Å; I411-M415 PolarHBondContact O-N 3.06Å; Q412-M415 PolarHBondContact O-N 3.3Å; T413-M415 VanDerWaalsContact C-N 3.3Å; T413-M415 PolarHBondContact O-N 3.18Å; M415-M417 PolarHBondContact O-N 3.49Å; M415-I418 PolarHBondContact O-N 3.4Å; M415-V419 HydrophobicContact CG-CG2 3.97Å; M415-V419 VanDerWaalsContact O-CB 3.23Å; M415-V419 WeakPolarHBondContact O-CB 3.39Å; M415-V419 WeakPolarHBondContact O-CG2 3.2Å; M415-V419 PolarHBondContact O-N 3.39Å; M415-Y436 HydrophobicContact CE-CD1 3.86Å; M415-Y436 HydrophobicContact CE-CE1 3.83Å; M415-Y436 HydrophobicContact CG-CE1 4.44Å; M415-Y436 HydrophobicContact SD-CD1 4.11Å; M415-Y436 HydrophobicContact SD-CE1 4.16Å; M415-Y439 HydrophobicContact SD-CD2 4.24Å; M415-Y439 HydrophobicContact SD-CE2 4.5Å
416	T	98.3	Very high	96.9	Very high	0 Å²	0	52.9 Å²	52.9	0%	0	26%	0.262	C	S	.	.	I	π-helix	trans	-57.2	-49.1	174.3	-66.4	0	0	0	0	111.3	P58 T61 Y62 Q288 Q412 T413 I418 V420 D421	P58-T416 HydrophobicContact CB-CG2 3.6Å; P58-T416 HydrophobicContact CG-CG2 4.14Å; T61-T416 PolarHBondContact OG1-OG1 3.25Å; Y62-T416 HydrophobicContact CE1-CG2 4.15Å; Q288-T416 PolarHBondContact NE2-OG1 2.97Å; Q412-T416 PolarHBondContact O-N 3.2Å; Q412-T416 PolarHBondContact O-OG1 2.96Å; T413-T416 PolarHBondContact O-N 3.46Å; T416-I418 VanDerWaalsContact C-N 3.3Å; T416-I418 PolarHBondContact O-N 3.05Å; T416-V420 HydrophobicContact CG2-CB 4.33Å; T416-V420 WeakPolarHBondContact O-CA 3.31Å; T416-V420 WeakPolarHBondContact O-CB 3.44Å; T416-V420 PolarHBondContact O-N 3.42Å; T416-D421 PolarHBondContact O-N 3.44Å
417	M	97.7	Very high	97	Very high	100 Å²	100	50.5 Å²	50.5	49%	0.493	25%	0.253	S	S	.	.	I	π-helix	trans	-60.4	-39.1	-177.9	-176.3	-172.6	67.8	0	0	112.4	Y62 T413 I414 M415 G424	Y62-M417 HydrophobicContact CE1-CB 4.48Å; Y62-M417 WeakPolarHBondContact OH-CA 3.34Å; T413-M417 WeakPolarHBondContact O-CB 3.4Å; T413-M417 PolarHBondContact O-N 3.49Å; I414-M417 PolarHBondContact O-N 2.95Å; M415-M417 PolarHBondContact O-N 3.49Å; M417-G424 VanDerWaalsContact O-CA 3.31Å; M417-G424 WeakPolarHBondContact O-CA 3.39Å
418	I	97.9	Very high	97	Very high	83 Å²	83	51.1 Å²	51.1	43%	0.426	26%	0.261	S	S	.	.	I	π-helix	trans	-80.7	-49.1	-178.8	-64.8	169.6	0	0	0	111.3	I414 M415 T416 L425	I414-I418 HydrophobicContact CG2-CD1 3.73Å; I414-I418 WeakPolarHBondContact O-CG1 3.48Å; I414-I418 PolarHBondContact O-N 2.86Å; M415-I418 PolarHBondContact O-N 3.4Å; T416-I418 VanDerWaalsContact C-N 3.3Å; T416-I418 PolarHBondContact O-N 3.05Å; I418-L425 HydrophobicContact CG2-CD1 4.19Å; I418-L425 VanDerWaalsContact O-CB 3.27Å; I418-L425 WeakPolarHBondContact O-CB 3.42Å; I418-L425 VanDerWaalsContact O-CG 3.27Å; I418-L425 WeakPolarHBondContact O-CG 3.21Å; I418-L425 PolarHBondContact O-N 3.32Å
419	V	97.6	Very high	96.9	Very high	11 Å²	11	51.3 Å²	51.3	7%	0.067	26%	0.262	C	S	.	.	I	π-helix	trans	-88.3	-40.1	-165.9	174.3	0	0	0	0	111.6	M415 L427 Q432 V435	M415-V419 HydrophobicContact CG-CG2 3.97Å; M415-V419 VanDerWaalsContact O-CB 3.23Å; M415-V419 WeakPolarHBondContact O-CB 3.39Å; M415-V419 WeakPolarHBondContact O-CG2 3.2Å; M415-V419 PolarHBondContact O-N 3.39Å; V419-L427 HydrophobicContact CG1-CD1 3.99Å; V419-L427 VanDerWaalsContact O-CB 3.32Å; V419-L427 WeakPolarHBondContact O-CB 3.5Å; V419-L427 WeakPolarHBondContact O-CG 3.37Å; V419-L427 PolarHBondContact O-N 2.87Å; V419-Q432 HydrophobicContact CG1-CB 4.32Å; V419-Q432 HydrophobicContact CG1-CG 4.07Å; V419-V435 HydrophobicContact CG1-CB 4.37Å; V419-V435 HydrophobicContact CG1-CG1 4.33Å; V419-V435 HydrophobicContact CG1-CG2 4.42Å; V419-V435 HydrophobicContact CG2-CG1 3.93Å
420	V	97.5	Very high	96.8	Very high	0 Å²	0	52.8 Å²	52.8	0%	0	27%	0.271	C	S	.	.	I	π-helix	trans	-108.1	-45.9	-165.2	-174.3	0	0	0	0	112.7	T53 N54 P58 Y292 T416 Q432 Y436	T53-V420 HydrophobicContact CG2-CG1 4.42Å; T53-V420 WeakPolarHBondContact O-CG1 3.37Å; N54-V420 WeakPolarHBondContact CB-O 3.37Å; N54-V420 PolarHBondContact ND2-O 2.91Å; P58-V420 HydrophobicContact CG-CG1 3.96Å; Y292-V420 HydrophobicContact CE1-CG1 3.76Å; Y292-V420 HydrophobicContact CE2-CG1 4.46Å; Y292-V420 HydrophobicContact CE2-CG2 3.94Å; Y292-V420 WeakPolarHBondContact OH-CG1 3.49Å; T416-V420 HydrophobicContact CG2-CB 4.33Å; T416-V420 WeakPolarHBondContact O-CA 3.31Å; T416-V420 WeakPolarHBondContact O-CB 3.44Å; T416-V420 PolarHBondContact O-N 3.42Å; V420-Q432 HydrophobicContact CG2-CG 4.36Å; V420-Y436 WeakPolarHBondContact CG2-OH 3.35Å
421	D	95.7	Very high	96.7	Very high	13 Å²	13	53 Å²	53	7%	0.07	27%	0.273	C	S	.	.	S	Bend	trans	-58.9	144.9	-172.8	-161.8	-71.5	0	0	0	112.2	Y62 T416 R423 G424 Q426	Y62-D421 VanDerWaalsContact CE2-OD2 3.24Å; Y62-D421 WeakPolarHBondContact CE2-OD2 3.25Å; Y62-D421 WeakPolarHBondContact OH-CB 3.36Å; Y62-D421 PolarHBondContact OH-OD2 3.38Å; T416-D421 PolarHBondContact O-N 3.44Å; D421-R423 PolarHBondContact O-N 2.97Å; D421-R423 WeakPolarHBondContact OD1-CB 3.42Å; D421-R423 WeakPolarHBondContact OD1-CG 3.45Å; D421-R423 PolarHBondContact OD1-N 3.33Å; D421-G424 WeakPolarHBondContact O-CA 3.49Å; D421-G424 PolarHBondContact O-N 3.23Å; D421-Q426 PolarHBondContact O-N 3.2Å
422	Q	93.2	Very high	96.6	Very high	88 Å²	88	51.5 Å²	51.5	41%	0.411	27%	0.265	S	S	.	.	T	Hydrogen-bonded Turn	trans	-55.8	-26.7	172.7	59.7	175.7	-27.7	0	0	114	N54 E55 G424	N54-Q422 PolarHBondContact O-N 2.89Å; E55-Q422 HydrophobicContact CG-CG 4.45Å; Q422-G424 VanDerWaalsContact C-N 3.34Å
423	R	93.3	Very high	96.6	Very high	224 Å²	224	51.5 Å²	51.5	85%	0.845	27%	0.265	S	S	*	.	T	Hydrogen-bonded Turn	trans	-79.8	-17.8	175.1	-60.2	175.3	-173.9	-179	3.5	113	D421	D421-R423 PolarHBondContact O-N 2.97Å; D421-R423 WeakPolarHBondContact OD1-CB 3.42Å; D421-R423 WeakPolarHBondContact OD1-CG 3.45Å; D421-R423 PolarHBondContact OD1-N 3.33Å
424	G	94.8	Very high	96.6	Very high	36 Å²	36	53 Å²	53	37%	0.371	27%	0.272	S	S	.	.	T	Hydrogen-bonded Turn	trans	-91.8	-132.9	177.4	0	0	0	0	0	111.5	M417 D421 Q422	M417-G424 VanDerWaalsContact O-CA 3.31Å; M417-G424 WeakPolarHBondContact O-CA 3.39Å; D421-G424 WeakPolarHBondContact O-CA 3.49Å; D421-G424 PolarHBondContact O-N 3.23Å; Q422-G424 VanDerWaalsContact C-N 3.34Å
425	L	95.8	Very high	96.6	Very high	108 Å²	108	51.2 Å²	51.2	57%	0.565	27%	0.265	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83.8	-11.5	178.6	-64.9	174	0	0	0	113.6	I418 L427	I418-L425 HydrophobicContact CG2-CD1 4.19Å; I418-L425 VanDerWaalsContact O-CB 3.27Å; I418-L425 WeakPolarHBondContact O-CB 3.42Å; I418-L425 VanDerWaalsContact O-CG 3.27Å; I418-L425 WeakPolarHBondContact O-CG 3.21Å; I418-L425 PolarHBondContact O-N 3.32Å; L425-L427 HydrophobicContact CB-CD1 4.21Å; L425-L427 HydrophobicContact CB-CD2 4Å; L425-L427 HydrophobicContact CB-CG 3.69Å; L425-L427 HydrophobicContact CD1-CD1 4.08Å; L425-L427 HydrophobicContact CD1-CG 4.45Å; L425-L427 PolarHBondContact O-N 3.43Å; L425-L427 VanDerWaalsContact O-N 3.15Å
426	Q	96.1	Very high	96.6	Very high	92 Å²	92	50.4 Å²	50.4	43%	0.43	26%	0.261	S	S	.	.			trans	46.4	44.6	-178.2	-160.7	-177.2	5.7	0	0	112.9	N54 D421	N54-Q426 HydrophobicContact CB-CG 3.85Å; D421-Q426 PolarHBondContact O-N 3.2Å
427	L	97	Very high	96.7	Very high	35 Å²	35	50.4 Å²	50.4	18%	0.183	26%	0.261	C	S	.	.			trans	-68.8	142.7	-172.7	-64.6	176.8	0	0	0	110.6	N54 V419 L425 T431 Q432 V435	N54-L427 PolarHBondContact ND2-O 2.67Å; V419-L427 HydrophobicContact CG1-CD1 3.99Å; V419-L427 VanDerWaalsContact O-CB 3.32Å; V419-L427 WeakPolarHBondContact O-CB 3.5Å; V419-L427 WeakPolarHBondContact O-CG 3.37Å; V419-L427 PolarHBondContact O-N 2.87Å; L425-L427 HydrophobicContact CB-CD1 4.21Å; L425-L427 HydrophobicContact CB-CD2 4Å; L425-L427 HydrophobicContact CB-CG 3.69Å; L425-L427 HydrophobicContact CD1-CD1 4.08Å; L425-L427 HydrophobicContact CD1-CG 4.45Å; L425-L427 PolarHBondContact O-N 3.43Å; L425-L427 VanDerWaalsContact O-N 3.15Å; L427-T431 HydrophobicContact CB-CG2 4.41Å; L427-T431 HydrophobicContact CD1-CG2 4.06Å; L427-T431 HydrophobicContact CD2-CG2 4.13Å; L427-T431 HydrophobicContact CG-CG2 4.42Å; L427-Q432 HydrophobicContact CB-CG 4.09Å; L427-Q432 PolarHBondContact O-NE2 2.78Å; L427-V435 HydrophobicContact CD1-CG2 4.15Å
428	P	95.9	Very high	96.7	Very high	77 Å²	77	48.1 Å²	48.1	50%	0.5	26%	0.255	S	S	.	.			trans	-68.1	152.3	171.8	29.6	-34.8	0	0	0	110.2	T430 T431 Q432	P428-T430 PolarHBondContact O-N 2.87Å; P428-T431 WeakPolarHBondContact O-CA 3.49Å; P428-T431 PolarHBondContact O-N 3.36Å; P428-Q432 WeakPolarHBondContact O-CG 3.38Å; P428-Q432 PolarHBondContact O-N 3.49Å
429	V	96.2	Very high	96.7	Very high	6 Å²	6	46.2 Å²	46.2	4%	0.036	24%	0.243	C	C	.	.	H	α-helix	trans	-50.9	-39.3	-172.5	68.8	0	0	0	0	113.9	V295 L296 H299 T431 Q432 F433	V295-V429 HydrophobicContact CB-CG2 4.08Å; V295-V429 HydrophobicContact CG1-CB 3.93Å; V295-V429 HydrophobicContact CG1-CG1 4.16Å; V295-V429 HydrophobicContact CG1-CG2 3.92Å; L296-V429 HydrophobicContact CB-CG2 3.94Å; L296-V429 HydrophobicContact CD1-CG1 4.34Å; L296-V429 HydrophobicContact CD1-CG2 4.44Å; H299-V429 HydrophobicContact CB-CG1 4.01Å; V429-T431 PolarHBondContact O-N 2.82Å; V429-Q432 WeakPolarHBondContact O-CB 3.31Å; V429-Q432 PolarHBondContact O-N 2.9Å; V429-Q432 VanDerWaalsContact O-N 3.15Å; V429-F433 HydrophobicContact CG2-CD2 4.02Å; V429-F433 HydrophobicContact CG2-CE2 3.98Å; V429-F433 WeakPolarHBondContact O-CD2 3.5Å; V429-F433 PolarHBondContact O-N 2.76Å
430	T	95.3	Very high	96.8	Very high	33 Å²	33	45.8 Å²	45.8	20%	0.202	24%	0.24	C	C	.	.	H	α-helix	trans	-59.3	-47.3	176.9	-58.2	0	0	0	0	111.4	H299 N358 P428 Q432 F433 L434	H299-T430 PolarHBondContact CD2-OG1 2.82Å; H299-T430 PolarHBondContact NE2-OG1 3.47Å; N358-T430 WeakPolarHBondContact OD1-CG2 3.21Å; N358-T430 PolarHBondContact OD1-O 3.5Å; P428-T430 PolarHBondContact O-N 2.87Å; T430-Q432 VanDerWaalsContact C-N 3.32Å; T430-Q432 PolarHBondContact O-N 3.22Å; T430-F433 PolarHBondContact O-N 3.05Å; T430-L434 PolarHBondContact O-N 3.02Å
431	T	96.8	Very high	96.8	Very high	53 Å²	53	47.7 Å²	47.7	33%	0.325	26%	0.256	S	S	.	.	H	α-helix	trans	-68	-31.8	176.6	-50.9	0	0	0	0	111.9	L427 P428 V429 L434 V435	L427-T431 HydrophobicContact CB-CG2 4.41Å; L427-T431 HydrophobicContact CD1-CG2 4.06Å; L427-T431 HydrophobicContact CD2-CG2 4.13Å; L427-T431 HydrophobicContact CG-CG2 4.42Å; P428-T431 WeakPolarHBondContact O-CA 3.49Å; P428-T431 PolarHBondContact O-N 3.36Å; V429-T431 PolarHBondContact O-N 2.82Å; T431-L434 WeakPolarHBondContact O-CB 3.32Å; T431-L434 PolarHBondContact O-N 3.22Å; T431-V435 WeakPolarHBondContact O-CG2 3.28Å; T431-V435 PolarHBondContact O-N 2.79Å
432	Q	97.8	Very high	96.9	Very high	0 Å²	0	51.8 Å²	51.8	0%	0	28%	0.281	C	S	.	.	H	α-helix	trans	-61.2	-44.6	173.3	-57.9	175.9	8.5	0	0	111.5	V419 V420 L427 P428 V429 T430 L434 V435 Y436	V419-Q432 HydrophobicContact CG1-CB 4.32Å; V419-Q432 HydrophobicContact CG1-CG 4.07Å; V420-Q432 HydrophobicContact CG2-CG 4.36Å; L427-Q432 HydrophobicContact CB-CG 4.09Å; L427-Q432 PolarHBondContact O-NE2 2.78Å; P428-Q432 WeakPolarHBondContact O-CG 3.38Å; P428-Q432 PolarHBondContact O-N 3.49Å; V429-Q432 WeakPolarHBondContact O-CB 3.31Å; V429-Q432 PolarHBondContact O-N 2.9Å; V429-Q432 VanDerWaalsContact O-N 3.15Å; T430-Q432 VanDerWaalsContact C-N 3.32Å; T430-Q432 PolarHBondContact O-N 3.22Å; Q432-L434 VanDerWaalsContact C-N 3.29Å; Q432-L434 PolarHBondContact O-N 3.28Å; Q432-V435 CarbonylContact O-C 3.59Å; Q432-V435 WeakPolarHBondContact O-CA 3.47Å; Q432-V435 WeakPolarHBondContact O-CB 3.28Å; Q432-V435 PolarHBondContact O-N 2.97Å; Q432-Y436 HydrophobicContact CB-CE2 3.84Å; Q432-Y436 VanDerWaalsContact O-CD2 3.31Å; Q432-Y436 WeakPolarHBondContact O-CD2 3.26Å; Q432-Y436 PolarHBondContact O-N 3.35Å
433	F	98	Very high	97.2	Very high	0 Å²	0	48.2 Å²	48.2	0%	0	27%	0.265	C	S	.	.	H	α-helix	trans	-65.2	-30.5	176.8	-88.4	-101.8	0	0	0	113.2	I289 V293 L296 L354 M357 N358 V429 T430 Y436 G437	I289-F433 HydrophobicContact CG2-CE1 4.18Å; I289-F433 HydrophobicContact CG2-CZ 4.44Å; V293-F433 HydrophobicContact CB-CZ 4.12Å; V293-F433 HydrophobicContact CG2-CZ 4.35Å; L296-F433 HydrophobicContact CB-CD2 4.23Å; L296-F433 HydrophobicContact CB-CE2 3.81Å; L296-F433 HydrophobicContact CB-CZ 4.16Å; L296-F433 HydrophobicContact CD1-CD2 4.36Å; L296-F433 HydrophobicContact CD2-CD1 3.71Å; L296-F433 HydrophobicContact CD2-CD2 3.95Å; L296-F433 HydrophobicContact CD2-CE1 3.74Å; L296-F433 HydrophobicContact CD2-CE2 3.99Å; L296-F433 HydrophobicContact CD2-CG 3.83Å; L296-F433 HydrophobicContact CD2-CZ 3.9Å; L296-F433 HydrophobicContact CG-CD2 4.41Å; L296-F433 HydrophobicContact CG-CE2 4.39Å; L354-F433 HydrophobicContact CD2-CD1 3.7Å; L354-F433 HydrophobicContact CD2-CE1 3.84Å; M357-F433 HydrophobicContact CE-CD1 4.24Å; M357-F433 HydrophobicContact CE-CE1 3.69Å; N358-F433 HydrophobicContact CB-CB 4.42Å; V429-F433 HydrophobicContact CG2-CD2 4.02Å; V429-F433 HydrophobicContact CG2-CE2 3.98Å; V429-F433 WeakPolarHBondContact O-CD2 3.5Å; V429-F433 PolarHBondContact O-N 2.76Å; T430-F433 PolarHBondContact O-N 3.05Å; F433-Y436 HydrophobicContact CD2-CD2 4.29Å; F433-Y436 HydrophobicContact CD2-CE2 4.37Å; F433-Y436 HydrophobicContact CE2-CE2 4.45Å; F433-Y436 HydrophobicContact CG-CD2 4.35Å; F433-Y436 PolarHBondContact O-N 2.93Å; F433-G437 PolarHBondContact O-N 3.18Å
434	L	97.9	Very high	97.4	Very high	53 Å²	53	38 Å²	38	28%	0.277	23%	0.228	S	C	.	.	H	α-helix	trans	-64	-41.9	169.1	-177.7	69.7	0	0	0	111.6	F355 Y359 T430 T431 Q432 S438	F355-L434 HydrophobicContact CD1-CD1 3.91Å; F355-L434 HydrophobicContact CE1-CD1 3.8Å; Y359-L434 HydrophobicContact CE2-CD1 4.38Å; T430-L434 PolarHBondContact O-N 3.02Å; T431-L434 WeakPolarHBondContact O-CB 3.32Å; T431-L434 PolarHBondContact O-N 3.22Å; Q432-L434 VanDerWaalsContact C-N 3.29Å; Q432-L434 PolarHBondContact O-N 3.28Å; L434-S438 WeakPolarHBondContact O-CB 3.49Å; L434-S438 PolarHBondContact O-N 3.07Å; L434-S438 PolarHBondContact O-OG 3.15Å
435	V	98.3	Very high	97.6	Very high	46 Å²	46	37.6 Å²	37.6	28%	0.279	22%	0.224	S	C	.	.	H	α-helix	trans	-64.4	-45.3	175.3	175.5	0	0	0	0	110.8	V419 L427 T431 Q432 G437 S438 Y439	V419-V435 HydrophobicContact CG1-CB 4.37Å; V419-V435 HydrophobicContact CG1-CG1 4.33Å; V419-V435 HydrophobicContact CG1-CG2 4.42Å; V419-V435 HydrophobicContact CG2-CG1 3.93Å; L427-V435 HydrophobicContact CD1-CG2 4.15Å; T431-V435 WeakPolarHBondContact O-CG2 3.28Å; T431-V435 PolarHBondContact O-N 2.79Å; Q432-V435 CarbonylContact O-C 3.59Å; Q432-V435 WeakPolarHBondContact O-CA 3.47Å; Q432-V435 WeakPolarHBondContact O-CB 3.28Å; Q432-V435 PolarHBondContact O-N 2.97Å; V435-G437 PolarHBondContact O-N 2.78Å; V435-S438 WeakPolarHBondContact O-CB 3.44Å; V435-S438 PolarHBondContact O-N 3.47Å; V435-Y439 WeakPolarHBondContact O-CB 3.45Å; V435-Y439 PolarHBondContact O-N 2.9Å
436	Y	98.4	Very high	97.6	Very high	0 Å²	0	35.6 Å²	35.6	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-64.4	-40.4	178.1	-53	-31.2	0	0	0	112.3	Q288 I289 Y292 M415 V420 Q432 F433 S438 Y439 F440	Q288-Y436 HydrophobicContact CB-CD1 4.28Å; Q288-Y436 HydrophobicContact CB-CE1 3.84Å; Q288-Y436 HydrophobicContact CB-CE2 4.27Å; Q288-Y436 HydrophobicContact CG-CE1 4.4Å; Q288-Y436 PolarHBondContact OE1-OH 3.35Å; I289-Y436 HydrophobicContact CG1-CD2 4.44Å; Y292-Y436 HydrophobicContact CD2-CE2 4.33Å; Y292-Y436 VanDerWaalsContact CD2-OH 3.24Å; Y292-Y436 WeakPolarHBondContact CD2-OH 3.38Å; M415-Y436 HydrophobicContact CE-CD1 3.86Å; M415-Y436 HydrophobicContact CE-CE1 3.83Å; M415-Y436 HydrophobicContact CG-CE1 4.44Å; M415-Y436 HydrophobicContact SD-CD1 4.11Å; M415-Y436 HydrophobicContact SD-CE1 4.16Å; V420-Y436 WeakPolarHBondContact CG2-OH 3.35Å; Q432-Y436 HydrophobicContact CB-CE2 3.84Å; Q432-Y436 VanDerWaalsContact O-CD2 3.31Å; Q432-Y436 WeakPolarHBondContact O-CD2 3.26Å; Q432-Y436 PolarHBondContact O-N 3.35Å; F433-Y436 HydrophobicContact CD2-CD2 4.29Å; F433-Y436 HydrophobicContact CD2-CE2 4.37Å; F433-Y436 HydrophobicContact CE2-CE2 4.45Å; F433-Y436 HydrophobicContact CG-CD2 4.35Å; F433-Y436 PolarHBondContact O-N 2.93Å; Y436-S438 VanDerWaalsContact C-N 3.34Å; Y436-S438 PolarHBondContact O-N 3.44Å; Y436-Y439 WeakPolarHBondContact O-CB 3.15Å; Y436-Y439 PolarHBondContact O-N 3.36Å; Y436-F440 WeakPolarHBondContact O-CD2 3.44Å; Y436-F440 PolarHBondContact O-N 2.98Å
437	G	98.5	Very high	97.6	Very high	0 Å²	0	31.9 Å²	31.9	0%	0	20%	0.198	C	C	.	.	H	α-helix	trans	-59.8	-44.6	172.4	0	0	0	0	0	112.1	A351 F433 V435 Y439 F440 A441	A351-G437 WeakPolarHBondContact CB-O 3.27Å; F433-G437 PolarHBondContact O-N 3.18Å; V435-G437 PolarHBondContact O-N 2.78Å; G437-Y439 PolarHBondContact O-N 3.24Å; G437-F440 PolarHBondContact O-N 3.01Å; G437-A441 WeakPolarHBondContact O-CB 3.5Å; G437-A441 PolarHBondContact O-N 2.71Å
438	S	98.5	Very high	97.5	Very high	53 Å²	53	34 Å²	34	37%	0.371	21%	0.21	S	C	.	.	H	α-helix	trans	-64.7	-39.5	177	-55.9	0	0	0	0	112.1	L434 V435 Y436 A441 V442	L434-S438 WeakPolarHBondContact O-CB 3.49Å; L434-S438 PolarHBondContact O-N 3.07Å; L434-S438 PolarHBondContact O-OG 3.15Å; V435-S438 WeakPolarHBondContact O-CB 3.44Å; V435-S438 PolarHBondContact O-N 3.47Å; Y436-S438 VanDerWaalsContact C-N 3.34Å; Y436-S438 PolarHBondContact O-N 3.44Å; S438-A441 WeakPolarHBondContact O-CB 3.46Å; S438-A441 PolarHBondContact O-N 3.49Å; S438-V442 WeakPolarHBondContact O-CG2 3.45Å; S438-V442 PolarHBondContact O-N 2.91Å
439	Y	98.5	Very high	97.5	Very high	43 Å²	43	36.4 Å²	36.4	17%	0.169	22%	0.216	C	C	.	.	H	α-helix	trans	-58.4	-50.3	175.1	175.3	-94.2	0	0	0	111.8	F281 M415 V435 Y436 G437 A441 V442 I443	F281-Y439 VanDerWaalsContact CA-OH 3.27Å; F281-Y439 WeakPolarHBondContact CA-OH 3.41Å; F281-Y439 HydrophobicContact CD1-CE2 4.38Å; F281-Y439 WeakPolarHBondContact CD1-OH 3.36Å; F281-Y439 WeakPolarHBondContact O-CE1 3.22Å; F281-Y439 PolarHBondContact O-OH 3.36Å; M415-Y439 HydrophobicContact SD-CD2 4.24Å; M415-Y439 HydrophobicContact SD-CE2 4.5Å; V435-Y439 WeakPolarHBondContact O-CB 3.45Å; V435-Y439 PolarHBondContact O-N 2.9Å; Y436-Y439 WeakPolarHBondContact O-CB 3.15Å; Y436-Y439 PolarHBondContact O-N 3.36Å; G437-Y439 PolarHBondContact O-N 3.24Å; Y439-A441 VanDerWaalsContact C-N 3.32Å; Y439-A441 PolarHBondContact O-N 3.16Å; Y439-V442 PolarHBondContact O-N 3.38Å; Y439-I443 HydrophobicContact CD1-CD1 3.82Å; Y439-I443 HydrophobicContact CE1-CD1 3.41Å; Y439-I443 VanDerWaalsContact CE1-CD1 3.41Å; Y439-I443 WeakPolarHBondContact O-CG1 3.25Å; Y439-I443 PolarHBondContact O-N 3.12Å; Y439-I443 VanDerWaalsContact O-N 3.12Å
440	F	98.6	Very high	97.4	Very high	1 Å²	1	38.8 Å²	38.8	0%	0.004	22%	0.224	C	C	.	.	H	α-helix	trans	-68.1	-29.9	176	-83.8	-78.9	0	0	0	113.1	A282 I289 I350 A351 L354 Y436 G437 I443 A444	A282-F440 HydrophobicContact CB-CE1 4.24Å; I289-F440 HydrophobicContact CD1-CD2 4.33Å; I289-F440 HydrophobicContact CD1-CE2 3.68Å; I289-F440 HydrophobicContact CD1-CZ 4.44Å; I350-F440 HydrophobicContact CB-CD1 4.19Å; I350-F440 HydrophobicContact CB-CG 4.3Å; I350-F440 HydrophobicContact CD1-CD1 4.37Å; I350-F440 HydrophobicContact CD1-CE1 4.13Å; I350-F440 HydrophobicContact CG2-CB 4.12Å; I350-F440 HydrophobicContact CG2-CD1 3.69Å; I350-F440 HydrophobicContact CG2-CD2 3.64Å; I350-F440 HydrophobicContact CG2-CE1 3.95Å; I350-F440 HydrophobicContact CG2-CE2 3.92Å; I350-F440 HydrophobicContact CG2-CG 3.53Å; I350-F440 HydrophobicContact CG2-CZ 4.05Å; A351-F440 HydrophobicContact CB-CB 3.88Å; L354-F440 HydrophobicContact CD1-CD2 3.81Å; L354-F440 HydrophobicContact CD1-CE2 4.42Å; Y436-F440 WeakPolarHBondContact O-CD2 3.44Å; Y436-F440 PolarHBondContact O-N 2.98Å; G437-F440 PolarHBondContact O-N 3.01Å; F440-I443 HydrophobicContact CD1-CD1 4.19Å; F440-I443 HydrophobicContact CE1-CD1 4.43Å; F440-I443 PolarHBondContact O-N 3Å; F440-A444 WeakPolarHBondContact O-CB 3.44Å; F440-A444 PolarHBondContact O-N 3.17Å
441	A	98.6	Very high	97.3	Very high	40 Å²	40	37.4 Å²	37.4	33%	0.331	22%	0.215	S	C	.	.	H	α-helix	trans	-65.3	-39.5	173.7	0	0	0	0	0	111.9	A351 F355 G437 S438 Y439 A444 G445	A351-A441 HydrophobicContact CB-CB 4.04Å; F355-A441 HydrophobicContact CE2-CB 4.35Å; G437-A441 WeakPolarHBondContact O-CB 3.5Å; G437-A441 PolarHBondContact O-N 2.71Å; S438-A441 WeakPolarHBondContact O-CB 3.46Å; S438-A441 PolarHBondContact O-N 3.49Å; Y439-A441 VanDerWaalsContact C-N 3.32Å; Y439-A441 PolarHBondContact O-N 3.16Å; A441-A444 PolarHBondContact O-N 2.96Å; A441-G445 PolarHBondContact O-N 2.89Å
442	V	98.4	Very high	97.2	Very high	100 Å²	100	39.3 Å²	39.3	61%	0.606	22%	0.223	S	C	*	.	H	α-helix	trans	-64.1	-45.6	173.5	172.5	0	0	0	0	110.7	S438 Y439 A444 G445 V446	S438-V442 WeakPolarHBondContact O-CG2 3.45Å; S438-V442 PolarHBondContact O-N 2.91Å; Y439-V442 PolarHBondContact O-N 3.38Å; V442-A444 VanDerWaalsContact C-N 3.32Å; V442-A444 PolarHBondContact O-N 2.95Å; V442-G445 PolarHBondContact O-N 3.45Å; V442-V446 WeakPolarHBondContact O-CG2 3.32Å; V442-V446 PolarHBondContact O-N 3.39Å
443	I	97.8	Very high	97	Very high	13 Å²	13	47.1 Å²	47.1	7%	0.067	25%	0.254	C	S	.	.	H	α-helix	trans	-56.4	-49.2	174.8	-65.9	170.4	0	0	0	110.1	F281 Y439 F440 G445 V446 F447	F281-I443 HydrophobicContact CB-CD1 3.84Å; F281-I443 HydrophobicContact CB-CG1 4.42Å; Y439-I443 HydrophobicContact CD1-CD1 3.82Å; Y439-I443 HydrophobicContact CE1-CD1 3.41Å; Y439-I443 VanDerWaalsContact CE1-CD1 3.41Å; Y439-I443 WeakPolarHBondContact O-CG1 3.25Å; Y439-I443 PolarHBondContact O-N 3.12Å; Y439-I443 VanDerWaalsContact O-N 3.12Å; F440-I443 HydrophobicContact CD1-CD1 4.19Å; F440-I443 HydrophobicContact CE1-CD1 4.43Å; F440-I443 PolarHBondContact O-N 3Å; I443-G445 VanDerWaalsContact C-N 3.32Å; I443-G445 PolarHBondContact O-N 2.71Å; I443-V446 PolarHBondContact O-N 3.43Å; I443-F447 HydrophobicContact CG2-CD2 3.96Å; I443-F447 HydrophobicContact CG2-CE2 4.22Å; I443-F447 WeakPolarHBondContact O-CD2 3.4Å; I443-F447 PolarHBondContact O-N 2.82Å; I443-F447 VanDerWaalsContact O-N 3.1Å
444	A	98.3	Very high	96.6	Very high	8 Å²	8	48.9 Å²	48.9	7%	0.066	26%	0.262	C	S	.	.	H	α-helix	trans	-57.8	-44.4	178.1	0	0	0	0	0	111.9	A348 F440 A441 V442 F447 L448	A348-A444 HydrophobicContact CB-CB 3.98Å; F440-A444 WeakPolarHBondContact O-CB 3.44Å; F440-A444 PolarHBondContact O-N 3.17Å; A441-A444 PolarHBondContact O-N 2.96Å; V442-A444 VanDerWaalsContact C-N 3.32Å; V442-A444 PolarHBondContact O-N 2.95Å; A444-F447 PolarHBondContact O-N 2.91Å; A444-L448 WeakPolarHBondContact O-CB 3.15Å; A444-L448 PolarHBondContact O-N 2.77Å
445	G	97.9	Very high	96.3	Very high	28 Å²	28	48.9 Å²	48.9	29%	0.289	26%	0.263	S	S	.	.	H	α-helix	trans	-61.5	-44.6	177.5	0	0	0	0	0	113.2	A441 V442 I443 L448 M449	A441-G445 PolarHBondContact O-N 2.89Å; V442-G445 PolarHBondContact O-N 3.45Å; I443-G445 VanDerWaalsContact C-N 3.32Å; I443-G445 PolarHBondContact O-N 2.71Å; G445-L448 PolarHBondContact O-N 3.22Å; G445-M449 WeakPolarHBondContact O-CE 3.33Å; G445-M449 WeakPolarHBondContact O-CG 3.47Å; G445-M449 PolarHBondContact O-N 2.98Å
446	V	96.6	Very high	96.1	Very high	66 Å²	66	49.9 Å²	49.9	40%	0.4	27%	0.271	S	S	.	.	H	α-helix	trans	-61	-49.5	178.1	172	0	0	0	0	111.2	V442 I443 L448 M449 R450	V442-V446 WeakPolarHBondContact O-CG2 3.32Å; V442-V446 PolarHBondContact O-N 3.39Å; I443-V446 PolarHBondContact O-N 3.43Å; V446-L448 VanDerWaalsContact C-N 3.34Å; V446-L448 PolarHBondContact O-N 3.22Å; V446-M449 HydrophobicContact CG2-CE 4.43Å; V446-M449 PolarHBondContact O-N 2.9Å; V446-R450 WeakPolarHBondContact O-CG 3.42Å; V446-R450 PolarHBondContact O-N 3.27Å
447	F	95.9	Very high	95.7	Very high	14 Å²	14	52.2 Å²	52.2	6%	0.061	29%	0.287	C	S	.	.	H	α-helix	trans	-71.5	-28.5	179.8	-79.1	-80	0	0	0	112.8	W278 E340 L343 A344 I443 A444 R450 S451	W278-F447 HydrophobicContact CB-CE1 4.29Å; W278-F447 HydrophobicContact CB-CE2 3.83Å; W278-F447 HydrophobicContact CB-CZ 3.55Å; W278-F447 AromaticContact CD1-CD2 3.89Å; W278-F447 AromaticContact CD1-CE2 3.63Å; W278-F447 HydrophobicContact CG-CE2 4.12Å; W278-F447 HydrophobicContact CG-CZ 4.21Å; E340-F447 HydrophobicContact CB-CD1 4.4Å; E340-F447 HydrophobicContact CG-CD1 4.32Å; L343-F447 HydrophobicContact CB-CB 4.24Å; L343-F447 HydrophobicContact CB-CD1 4.13Å; L343-F447 HydrophobicContact CB-CG 4.09Å; L343-F447 HydrophobicContact CD1-CD1 3.61Å; L343-F447 HydrophobicContact CD1-CE1 3.54Å; L343-F447 HydrophobicContact CD1-CG 4.28Å; L343-F447 HydrophobicContact CD1-CZ 4.17Å; A344-F447 HydrophobicContact CB-CB 4.04Å; I443-F447 HydrophobicContact CG2-CD2 3.96Å; I443-F447 HydrophobicContact CG2-CE2 4.22Å; I443-F447 WeakPolarHBondContact O-CD2 3.4Å; I443-F447 PolarHBondContact O-N 2.82Å; I443-F447 VanDerWaalsContact O-N 3.1Å; A444-F447 PolarHBondContact O-N 2.91Å; F447-R450 PolarHBondContact O-N 3.48Å; F447-S451 WeakPolarHBondContact O-CB 3.38Å; F447-S451 PolarHBondContact O-N 3.23Å
448	L	96.3	Very high	95.2	Very high	80 Å²	80	54.1 Å²	54.1	42%	0.419	30%	0.303	S	S	.	.	H	α-helix	trans	-65.5	-47.5	173.9	-176.6	61.9	0	0	0	111.3	A344 A444 G445 V446 R450 S451 I452	A344-L448 HydrophobicContact CB-CB 3.96Å; A344-L448 HydrophobicContact CB-CD1 4.43Å; A444-L448 WeakPolarHBondContact O-CB 3.15Å; A444-L448 PolarHBondContact O-N 2.77Å; G445-L448 PolarHBondContact O-N 3.22Å; V446-L448 VanDerWaalsContact C-N 3.34Å; V446-L448 PolarHBondContact O-N 3.22Å; L448-R450 VanDerWaalsContact C-N 3.28Å; L448-R450 PolarHBondContact O-N 2.73Å; L448-S451 PolarHBondContact O-N 2.93Å; L448-I452 HydrophobicContact CD1-CD1 4.39Å; L448-I452 HydrophobicContact CG-CD1 4.14Å; L448-I452 VanDerWaalsContact O-CG1 3.3Å; L448-I452 WeakPolarHBondContact O-CG1 3.44Å; L448-I452 PolarHBondContact O-N 3.41Å
449	M	95.3	Very high	94.8	Very high	127 Å²	127	58 Å²	58	63%	0.626	31%	0.313	S	S	*	.	H	α-helix	trans	-58.4	-42.9	177.5	-72.4	-176.5	-70	0	0	111.6	G445 V446 Y453	G445-M449 WeakPolarHBondContact O-CE 3.33Å; G445-M449 WeakPolarHBondContact O-CG 3.47Å; G445-M449 PolarHBondContact O-N 2.98Å; V446-M449 HydrophobicContact CG2-CE 4.43Å; V446-M449 PolarHBondContact O-N 2.9Å; M449-Y453 PolarHBondContact O-N 2.94Å; M449-Y453 VanDerWaalsContact O-N 3.12Å
450	R	93.2	Very high	94.3	Very high	57 Å²	57	59.3 Å²	59.3	22%	0.215	33%	0.328	C	S	.	.	H	α-helix	trans	-70.5	-40.6	177.8	-64.2	178.8	52.9	70.7	9.7	112.9	Y274 E340 V446 F447 L448 I452 Y453 I454	Y274-R450 VanDerWaalsContact CE1-CZ 3.4Å; Y274-R450 PolarHBondContact OH-NH1 3.41Å; E340-R450 IonicContact OE1-CZ 3.32Å; E340-R450 IonicContact OE1-NE 3.03Å; E340-R450 PolarHBondContact OE1-NE 3.49Å; E340-R450 IonicContact OE1-NH2 2.74Å; E340-R450 PolarHBondContact OE1-NH2 2.86Å; E340-R450 WeakPolarHBondContact OE2-CB 3.34Å; E340-R450 IonicContact OE2-CZ 3.93Å; E340-R450 IonicContact OE2-NE 3.3Å; E340-R450 PolarHBondContact OE2-NE 2.97Å; E340-R450 IonicContact OE2-NH2 3.81Å; V446-R450 WeakPolarHBondContact O-CG 3.42Å; V446-R450 PolarHBondContact O-N 3.27Å; F447-R450 PolarHBondContact O-N 3.48Å; L448-R450 VanDerWaalsContact C-N 3.28Å; L448-R450 PolarHBondContact O-N 2.73Å; R450-I452 VanDerWaalsContact C-N 3.29Å; R450-I452 PolarHBondContact O-N 3.45Å; R450-Y453 CarbonylContact O-C 3.59Å; R450-Y453 WeakPolarHBondContact O-CA 3.5Å; R450-Y453 WeakPolarHBondContact O-CB 3.18Å; R450-Y453 PolarHBondContact O-N 2.9Å; R450-I454 WeakPolarHBondContact O-CG1 3.48Å; R450-I454 PolarHBondContact O-N 3.26Å
451	S	93.8	Very high	93.8	Very high	3 Å²	3	67.8 Å²	67.8	2%	0.021	36%	0.36	C	S	.	.	H	α-helix	trans	-56.8	-45.2	174.5	177.8	0	0	0	0	111.1	E340 L341 F447 L448 Y453 I454 L455	E340-S451 PolarHBondContact OE2-N 3.46Å; L341-S451 WeakPolarHBondContact CA-OG 3.41Å; L341-S451 VanDerWaalsContact CB-OG 3.26Å; L341-S451 WeakPolarHBondContact CB-OG 3.46Å; L341-S451 PolarHBondContact N-OG 3.44Å; F447-S451 WeakPolarHBondContact O-CB 3.38Å; F447-S451 PolarHBondContact O-N 3.23Å; L448-S451 PolarHBondContact O-N 2.93Å; S451-Y453 VanDerWaalsContact C-N 3.32Å; S451-Y453 PolarHBondContact O-N 3.46Å; S451-I454 PolarHBondContact O-N 2.94Å; S451-L455 WeakPolarHBondContact O-CB 3.43Å; S451-L455 PolarHBondContact O-N 3.21Å
452	I	94.5	Very high	93.1	Very high	94 Å²	94	72.5 Å²	72.5	48%	0.482	37%	0.373	S	S	.	.	H	α-helix	trans	-58.9	-44.9	174.6	-67.4	165.3	0	0	0	110.4	L448 R450 L455 C456	L448-I452 HydrophobicContact CD1-CD1 4.39Å; L448-I452 HydrophobicContact CG-CD1 4.14Å; L448-I452 VanDerWaalsContact O-CG1 3.3Å; L448-I452 WeakPolarHBondContact O-CG1 3.44Å; L448-I452 PolarHBondContact O-N 3.41Å; R450-I452 VanDerWaalsContact C-N 3.29Å; R450-I452 PolarHBondContact O-N 3.45Å; I452-L455 PolarHBondContact O-N 2.96Å; I452-C456 VanDerWaalsContact O-CB 3.24Å; I452-C456 WeakPolarHBondContact O-CB 3.4Å; I452-C456 PolarHBondContact O-N 2.84Å; I452-C456 PolarHBondContact O-SG 3.23Å
453	Y	93.1	Very high	92.3	Very high	164 Å²	164	73.3 Å²	73.3	64%	0.643	37%	0.37	S	S	*	.	H	α-helix	trans	-60.3	-45.8	176.7	173.9	-95.9	0	0	0	112.9	M449 R450 S451 S457	M449-Y453 PolarHBondContact O-N 2.94Å; M449-Y453 VanDerWaalsContact O-N 3.12Å; R450-Y453 CarbonylContact O-C 3.59Å; R450-Y453 WeakPolarHBondContact O-CA 3.5Å; R450-Y453 WeakPolarHBondContact O-CB 3.18Å; R450-Y453 PolarHBondContact O-N 2.9Å; S451-Y453 VanDerWaalsContact C-N 3.32Å; S451-Y453 PolarHBondContact O-N 3.46Å; Y453-S457 VanDerWaalsContact O-CB 3.26Å; Y453-S457 WeakPolarHBondContact O-CB 3.5Å; Y453-S457 PolarHBondContact O-N 2.94Å; Y453-S457 PolarHBondContact O-OG 3.49Å
454	I	91.2	Very high	91.5	Very high	36 Å²	36	77.4 Å²	77.4	19%	0.185	40%	0.395	C	S	.	.	H	α-helix	trans	-63.8	-45.7	178	-66.9	179	0	0	0	110.4	L337 E340 R450 S451 S457 A458	L337-I454 HydrophobicContact CD1-CG2 4.14Å; E340-I454 HydrophobicContact CG-CD1 4.02Å; E340-I454 WeakPolarHBondContact OE1-CD1 3.46Å; E340-I454 WeakPolarHBondContact OE2-CD1 3.38Å; R450-I454 WeakPolarHBondContact O-CG1 3.48Å; R450-I454 PolarHBondContact O-N 3.26Å; S451-I454 PolarHBondContact O-N 2.94Å; I454-S457 WeakPolarHBondContact CA-OG 3.17Å; I454-S457 PolarHBondContact O-N 2.99Å; I454-S457 PolarHBondContact O-OG 3.3Å; I454-A458 VanDerWaalsContact O-CB 3.26Å; I454-A458 WeakPolarHBondContact O-CB 3.46Å; I454-A458 PolarHBondContact O-N 2.98Å
455	L	91.6	Very high	90.5	Very high	54 Å²	54	82.6 Å²	82.6	28%	0.283	42%	0.418	S	S	.	.	H	α-helix	trans	-67.2	-41.4	-178.1	-138.1	71.8	0	0	0	111.8	L337 L338 S451 I452 K459	L337-L455 HydrophobicContact CD1-CD1 3.86Å; L337-L455 HydrophobicContact CD2-CD1 4.39Å; L337-L455 HydrophobicContact CG-CD1 3.87Å; L338-L455 HydrophobicContact CD2-CD1 4.32Å; S451-L455 WeakPolarHBondContact O-CB 3.43Å; S451-L455 PolarHBondContact O-N 3.21Å; I452-L455 PolarHBondContact O-N 2.96Å; L455-K459 WeakPolarHBondContact O-CB 3.48Å; L455-K459 WeakPolarHBondContact O-CG 3.35Å; L455-K459 PolarHBondContact O-N 3.15Å
456	C	92.4	Very high	89.6	Confident	67 Å²	67	85.3 Å²	85.3	45%	0.453	43%	0.426	S	S	.	.	H	α-helix	trans	-65.8	-46.3	175.1	-72	0	0	0	0	111.4	I452 A458 K459 C460	I452-C456 VanDerWaalsContact O-CB 3.24Å; I452-C456 WeakPolarHBondContact O-CB 3.4Å; I452-C456 PolarHBondContact O-N 2.84Å; I452-C456 PolarHBondContact O-SG 3.23Å; C456-A458 VanDerWaalsContact C-N 3.33Å; C456-A458 PolarHBondContact O-N 3.28Å; C456-K459 PolarHBondContact O-N 3.05Å; C456-C460 PolarHBondContact O-N 3.44Å; C456-C460 PolarHBondContact O-SG 2.97Å
457	S	90.8	Very high	88.6	Confident	49 Å²	49	88.1 Å²	88.1	34%	0.343	44%	0.438	S	S	.	.	H	α-helix	trans	-64.6	-36.5	178.5	61.9	0	0	0	0	112.8	Y453 I454 R461	Y453-S457 VanDerWaalsContact O-CB 3.26Å; Y453-S457 WeakPolarHBondContact O-CB 3.5Å; Y453-S457 PolarHBondContact O-N 2.94Å; Y453-S457 PolarHBondContact O-OG 3.49Å; I454-S457 WeakPolarHBondContact CA-OG 3.17Å; I454-S457 PolarHBondContact O-N 2.99Å; I454-S457 PolarHBondContact O-OG 3.3Å; S457-R461 WeakPolarHBondContact O-CB 3.4Å; S457-R461 PolarHBondContact O-N 3.21Å
458	A	89.1	Confident	87.5	Confident	40 Å²	40	90.4 Å²	90.4	33%	0.331	46%	0.46	S	S	.	.	H	α-helix	trans	-66.1	-42.3	173.6	0	0	0	0	0	112	L337 I454 C456 R461 K462	L337-A458 HydrophobicContact CD1-CB 3.77Å; I454-A458 VanDerWaalsContact O-CB 3.26Å; I454-A458 WeakPolarHBondContact O-CB 3.46Å; I454-A458 PolarHBondContact O-N 2.98Å; C456-A458 VanDerWaalsContact C-N 3.33Å; C456-A458 PolarHBondContact O-N 3.28Å; A458-R461 PolarHBondContact O-N 3.05Å; A458-K462 WeakPolarHBondContact O-CB 3.32Å; A458-K462 PolarHBondContact O-N 3.44Å
459	K	89	Confident	86.4	Confident	133 Å²	133	91.4 Å²	91.4	58%	0.578	47%	0.469	S	S	*	.	H	α-helix	trans	-61.7	-49.5	174	-77.8	179.4	179.9	-177	0	111.7	L455 C456 R461 K462 E463	L455-K459 WeakPolarHBondContact O-CB 3.48Å; L455-K459 WeakPolarHBondContact O-CG 3.35Å; L455-K459 PolarHBondContact O-N 3.15Å; C456-K459 PolarHBondContact O-N 3.05Å; K459-R461 VanDerWaalsContact C-N 3.31Å; K459-R461 PolarHBondContact O-N 3.06Å; K459-K462 WeakPolarHBondContact O-CB 3.36Å; K459-K462 PolarHBondContact O-N 3.26Å; K459-K462 VanDerWaalsContact O-N 3.09Å; K459-E463 PolarHBondContact O-N 3.35Å
460	C	88.4	Confident	84.9	Confident	71 Å²	71	90.5 Å²	90.5	48%	0.48	47%	0.471	S	S	.	.	H	α-helix	trans	-59.2	-41.2	177.6	-66	0	0	0	0	111.9	C456 K462 E463 V464	C456-C460 PolarHBondContact O-N 3.44Å; C456-C460 PolarHBondContact O-SG 2.97Å; C460-K462 VanDerWaalsContact C-N 3.33Å; C460-K462 PolarHBondContact O-N 2.78Å; C460-E463 PolarHBondContact O-N 2.9Å; C460-V464 WeakPolarHBondContact O-CG2 3.32Å; C460-V464 PolarHBondContact O-N 2.9Å
461	R	87	Confident	83.2	Confident	180 Å²	180	98.7 Å²	98.7	68%	0.679	50%	0.502	S	S	*	.	H	α-helix	trans	-62.4	-40.9	176	-169.8	-177.5	-66.2	-171.3	-0.3	111.8	S457 A458 K459 Q465	S457-R461 WeakPolarHBondContact O-CB 3.4Å; S457-R461 PolarHBondContact O-N 3.21Å; A458-R461 PolarHBondContact O-N 3.05Å; K459-R461 VanDerWaalsContact C-N 3.31Å; K459-R461 PolarHBondContact O-N 3.06Å; R461-Q465 WeakPolarHBondContact O-CB 3.21Å; R461-Q465 WeakPolarHBondContact O-CG 3.03Å; R461-Q465 PolarHBondContact O-N 3.06Å
462	K	84.8	Confident	81.3	Confident	138 Å²	138	103.4 Å²	103.4	60%	0.6	54%	0.535	S	S	*	.	H	α-helix	trans	-66.8	-40	177.7	-167.5	176.8	-177.7	179.9	0	112	A458 K459 C460 Q465 N466	A458-K462 WeakPolarHBondContact O-CB 3.32Å; A458-K462 PolarHBondContact O-N 3.44Å; K459-K462 WeakPolarHBondContact O-CB 3.36Å; K459-K462 PolarHBondContact O-N 3.26Å; K459-K462 VanDerWaalsContact O-N 3.09Å; C460-K462 VanDerWaalsContact C-N 3.33Å; C460-K462 PolarHBondContact O-N 2.78Å; K462-Q465 PolarHBondContact O-N 2.99Å; K462-N466 WeakPolarHBondContact O-CB 3.49Å; K462-N466 PolarHBondContact O-N 3.13Å; K462-N466 PolarHBondContact O-ND2 3.2Å; K462-N466 PolarHBondContact O-OD1 3.31Å
463	E	82.4	Confident	79.2	Confident	118 Å²	118	103.5 Å²	103.5	55%	0.551	54%	0.541	S	S	*	.	H	α-helix	trans	-63.2	-46.5	175.3	-74.3	174.4	179.3	0	0	111.8	K459 C460 Q465 N466 L467	K459-E463 PolarHBondContact O-N 3.35Å; C460-E463 PolarHBondContact O-N 2.9Å; E463-Q465 VanDerWaalsContact C-N 3.32Å; E463-Q465 PolarHBondContact O-N 3.35Å; E463-N466 PolarHBondContact O-N 2.84Å; E463-L467 WeakPolarHBondContact O-CB 3.27Å; E463-L467 WeakPolarHBondContact O-CD1 3.42Å; E463-L467 PolarHBondContact O-N 3.02Å
464	V	80.3	Confident	76.9	Confident	99 Å²	99	102.9 Å²	102.9	60%	0.6	55%	0.549	S	S	*	.	H	α-helix	trans	-60.8	-41.7	176.3	172.4	0	0	0	0	111.5	C460 L467 A468	C460-V464 WeakPolarHBondContact O-CG2 3.32Å; C460-V464 PolarHBondContact O-N 2.9Å; V464-L467 PolarHBondContact O-N 3.01Å; V464-A468 PolarHBondContact O-N 3.35Å
465	Q	77.8	Confident	74.6	Confident	116 Å²	116	110 Å²	110	54%	0.542	58%	0.582	S	S	.	*	H	α-helix	trans	-63.7	-44.4	176.2	-76.9	176.3	-16.5	0	0	112.2	R461 K462 E463 L467 A468 T469	R461-Q465 WeakPolarHBondContact O-CB 3.21Å; R461-Q465 WeakPolarHBondContact O-CG 3.03Å; R461-Q465 PolarHBondContact O-N 3.06Å; K462-Q465 PolarHBondContact O-N 2.99Å; E463-Q465 VanDerWaalsContact C-N 3.32Å; E463-Q465 PolarHBondContact O-N 3.35Å; Q465-L467 VanDerWaalsContact C-N 3.33Å; Q465-L467 PolarHBondContact O-N 3.21Å; Q465-A468 PolarHBondContact O-N 3.39Å; Q465-T469 PolarHBondContact O-N 3.05Å; Q465-T469 VanDerWaalsContact O-N 3.08Å; Q465-T469 PolarHBondContact O-OG1 2.82Å
466	N	78.3	Confident	72.4	Confident	86 Å²	86	113.2 Å²	113.2	46%	0.46	61%	0.606	S	S	.	*	H	α-helix	trans	-63.2	-38.7	177.1	-70.1	-13.1	0	0	0	112.2	K462 E463 A468 T469 T470	K462-N466 WeakPolarHBondContact O-CB 3.49Å; K462-N466 PolarHBondContact O-N 3.13Å; K462-N466 PolarHBondContact O-ND2 3.2Å; K462-N466 PolarHBondContact O-OD1 3.31Å; E463-N466 PolarHBondContact O-N 2.84Å; N466-A468 VanDerWaalsContact C-N 3.34Å; N466-T469 PolarHBondContact O-OG1 3.37Å; N466-T470 PolarHBondContact O-N 3.47Å; N466-T470 PolarHBondContact O-OG1 3.36Å
467	L	75.7	Confident	69.8	Low	124 Å²	124	118.8 Å²	118.8	65%	0.649	63%	0.625	S	S	*	*	H	α-helix	trans	-64.7	-36.6	174.8	-92.9	141.8	0	0	0	112.4	E463 V464 Q465	E463-L467 WeakPolarHBondContact O-CB 3.27Å; E463-L467 WeakPolarHBondContact O-CD1 3.42Å; E463-L467 PolarHBondContact O-N 3.02Å; V464-L467 PolarHBondContact O-N 3.01Å; Q465-L467 VanDerWaalsContact C-N 3.33Å; Q465-L467 PolarHBondContact O-N 3.21Å
468	A	73.5	Confident	67.7	Low	62 Å²	62	122.1 Å²	122.1	51%	0.512	65%	0.645	S	S	.	*	H	α-helix	trans	-68.8	-44.2	176.6	0	0	0	0	0	112.4	V464 Q465 N466 T470 R471	V464-A468 PolarHBondContact O-N 3.35Å; Q465-A468 PolarHBondContact O-N 3.39Å; N466-A468 VanDerWaalsContact C-N 3.34Å; A468-T470 VanDerWaalsContact C-N 3.31Å; A468-T470 PolarHBondContact O-N 3.15Å; A468-R471 PolarHBondContact O-N 3.32Å
469	T	71.3	Confident	65.4	Low	102 Å²	102	129.2 Å²	129.2	63%	0.626	67%	0.672	S	S	*	*	H	α-helix	trans	-65.4	-32.9	177.8	18.4	0	0	0	0	113	Q465 N466 R471 S472	Q465-T469 PolarHBondContact O-N 3.05Å; Q465-T469 VanDerWaalsContact O-N 3.08Å; Q465-T469 PolarHBondContact O-OG1 2.82Å; N466-T469 PolarHBondContact O-OG1 3.37Å; T469-R471 PolarHBondContact O-N 2.96Å; T469-S472 PolarHBondContact O-N 3.47Å
470	T	65.3	Low	63	Low	107 Å²	107	131.6 Å²	131.6	66%	0.656	69%	0.685	S	S	*	*	H	α-helix	trans	-71.2	-20.2	179.8	-43.9	0	0	0	0	112.6	N466 A468 P473	N466-T470 PolarHBondContact O-N 3.47Å; N466-T470 PolarHBondContact O-OG1 3.36Å; A468-T470 VanDerWaalsContact C-N 3.31Å; A468-T470 PolarHBondContact O-N 3.15Å; T470-P473 WeakPolarHBondContact O-CD 3.08Å
471	R	57.9	Low	60.9	Low	230 Å²	230	133.8 Å²	133.8	87%	0.868	70%	0.699	S	S	*	*	H	α-helix	trans	-86.6	-14.8	177.8	-92.2	-175.8	177.7	174.4	0	115	A468 T469	A468-R471 PolarHBondContact O-N 3.32Å; T469-R471 PolarHBondContact O-N 2.96Å
472	S	52.7	Low	58.7	Low	101 Å²	101	130.3 Å²	130.3	71%	0.706	70%	0.702	S	S	*	*			trans	-93.8	24	-179.3	-79.9	0	0	0	0	119	T469	T469-S472 PolarHBondContact O-N 3.47Å
473	P	49.8	Very low	56.6	Low	96 Å²	96	131.6 Å²	131.6	62%	0.623	72%	0.715	S	S	*	*	S	Bend	trans	-77.5	-8.7	172.8	-16.5	30.2	0	0	0	117.3	T470	T470-P473 WeakPolarHBondContact O-CD 3.08Å
474	N	45.3	Very low	54.7	Low	151 Å²	151	131.8 Å²	131.8	81%	0.807	72%	0.724	S	S	*	*			trans	-132.6	52.1	-166.1	-78.8	-17.8	0	0	0	115.2
475	E	42.7	Very low	52.8	Low	185 Å²	185	132.3 Å²	132.3	86%	0.864	73%	0.732	S	S	*	*			trans	-108.5	106.4	159.5	-82.4	-174.3	160.8	0	0	109.7	H477	E475-H477 PolarHBondContact O-N 3.1Å
476	P	45.4	Very low	51	Low	123 Å²	123	132.8 Å²	132.8	80%	0.799	74%	0.743	S	S	*	*			trans	-65	129.5	169	-9.1	23.9	0	0	0	108.6
477	H	38.2	Very low	48.9	Very low	183 Å²	183	138 Å²	138	85%	0.847	76%	0.761	S	S	*	*			trans	-42.8	124.3	177.7	-88.3	-51	0	0	0	112.6	E475 Q479	E475-H477 PolarHBondContact O-N 3.1Å; H477-Q479 PolarHBondContact O-N 2.88Å
478	P	46.7	Very low	47.3	Very low	119 Å²	119	145.2 Å²	145.2	77%	0.773	79%	0.788	S	S	*	*	P	Polyproline II helix	trans	-69.2	118.9	169.8	26.4	-28.1	0	0	0	108.3	E480	P478-E480 PolarHBondContact O-N 2.79Å
479	Q	40.7	Very low	46	Very low	189 Å²	189	149.4 Å²	149.4	88%	0.883	80%	0.802	S	S	*	*	P	Polyproline II helix	trans	-52.7	128.1	173.9	-76.4	178.6	-33.1	0	0	110.4	H477	H477-Q479 PolarHBondContact O-N 2.88Å
480	E	38.1	Very low	44.7	Very low	183 Å²	183	151.8 Å²	151.8	86%	0.855	81%	0.811	S	S	*	*	P	Polyproline II helix	trans	-54.8	135.9	173.4	-85.2	176.4	137.2	0	0	111.4	P478 S482	P478-E480 PolarHBondContact O-N 2.79Å; E480-S482 PolarHBondContact O-N 3.03Å
481	P	44.9	Very low	43.6	Very low	118 Å²	118	154.3 Å²	154.3	77%	0.766	82%	0.82	S	S	*	*			trans	-71.4	113.5	174.4	28.6	-31	0	0	0	109.4	N483	P481-N483 PolarHBondContact O-N 3.28Å
482	S	40.8	Very low	42.7	Very low	107 Å²	107	149.9 Å²	149.9	75%	0.748	82%	0.817	S	S	*	*			trans	-55.7	119.1	172.3	48.9	0	0	0	0	111.2	E480 V484	E480-S482 PolarHBondContact O-N 3.03Å; S482-V484 PolarHBondContact O-N 3Å
483	N	41.2	Very low	42.1	Very low	165 Å²	165	152.9 Å²	152.9	88%	0.882	82%	0.824	S	S	*	*			trans	-61.1	101.9	170.8	-84.5	-34.4	0	0	0	109.9	P481 S485	P481-N483 PolarHBondContact O-N 3.28Å; N483-S485 PolarHBondContact O-N 3.44Å; N483-S485 VanDerWaalsContact O-N 3.08Å
484	V	41.8	Very low	41.6	Very low	122 Å²	122	156.7 Å²	156.7	74%	0.739	84%	0.837	S	S	*	*			trans	-74.4	96.7	167	179.6	0	0	0	0	107.7	S482 T486	S482-V484 PolarHBondContact O-N 3Å; V484-T486 PolarHBondContact O-N 3.43Å
485	S	40.3	Very low	41.3	Very low	109 Å²	109	157.1 Å²	157.1	76%	0.762	84%	0.839	S	S	*	*			trans	-77.8	97.7	169.7	-164.9	0	0	0	0	108.6	N483 K487	N483-S485 PolarHBondContact O-N 3.44Å; N483-S485 VanDerWaalsContact O-N 3.08Å; S485-K487 PolarHBondContact O-N 3.05Å; S485-K487 VanDerWaalsContact O-N 3.15Å
486	T	40.6	Very low	41.2	Very low	126 Å²	126	155 Å²	155	77%	0.773	84%	0.837	S	S	*	*			trans	-75.2	94.4	167.7	18.6	0	0	0	0	109	V484	V484-T486 PolarHBondContact O-N 3.43Å
487	K	34.2	Very low	40.9	Very low	195 Å²	195	157.7 Å²	157.7	85%	0.848	84%	0.841	S	S	*	*			trans	-65.4	129	157.5	-86.8	-179.8	172.8	178.8	0	109.1	S485	S485-K487 PolarHBondContact O-N 3.05Å; S485-K487 VanDerWaalsContact O-N 3.15Å
488	F	42.8	Very low	41.1	Very low	276 Å²	276	155.4 Å²	155.4	100%	1.211	84%	0.84	S	S	*	*			trans	-84	0	144.7	-89	-82.4	0	0	0	109.2

Retrieved 488 of 488 residues in 99 ms (Link to these results)

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