Q99PN8_MOUSE Loading...

Alpha ENaC

AlphaFold DB , UniProt , Accession Q99PN8, Species MOUSE (Mus musculus, Mouse), Gene Scnn1a, Length 56 aa.

						>Q99PN8_MOUSE|Q99PN8|Scnn1a
MLDHTRAPELNLDLDLDVSNSPKGSMKGNNFKEQDLCPPLPMQGLGKGTSVKNRRW
					

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	41.5	Very low	56.6	Low	228 Å²	228	146.7 Å²	146.7	100%	1.123	77%	0.77	S	S	*	*				0	116	0	-78.1	171.9	-102.9	0	0	105.8
2	L	48.8	Very low	56.9	Low	150 Å²	150	146.4 Å²	146.4	79%	0.785	77%	0.768	S	S	*	*			trans	-89	102	-178.5	-93.3	147.3	0	0	0	107.3	H4	L2-H4 PolarHBondContact O-N 3.01Å
3	D	51.4	Low	57.5	Low	145 Å²	145	146.5 Å²	146.5	78%	0.775	77%	0.769	S	S	*	*			trans	-74.4	91.8	177.9	-64.1	-53.3	0	0	0	109.7	T5	D3-T5 PolarHBondContact O-N 2.95Å
4	H	60.4	Low	58	Low	160 Å²	160	146.5 Å²	146.5	74%	0.741	77%	0.769	S	S	*	*			trans	-87.4	74	171.7	-66.4	-41	0	0	0	110.6	L2	L2-H4 PolarHBondContact O-N 3.01Å
5	T	58.8	Low	58.5	Low	135 Å²	135	147.2 Å²	147.2	83%	0.828	77%	0.774	S	S	*	*			trans	-133.8	60.2	167.3	49.7	0	0	0	0	111.1	D3	D3-T5 PolarHBondContact O-N 2.95Å
6	R	55.8	Low	58.5	Low	197 Å²	197	146.6 Å²	146.6	74%	0.743	77%	0.771	S	S	*	*			trans	-120.7	109.7	160.5	-164.1	168.8	-177	173	-2.3	107.9	E9	R6-E9 IonicContact NE-OE1 3.62Å; R6-E9 IonicContact NH2-OE1 2.74Å; R6-E9 PolarHBondContact NH2-OE1 3.4Å; R6-E9 IonicContact NH2-OE2 3.52Å; R6-E9 IonicContact CZ-OE1 3.55Å
7	A	64.4	Low	58.8	Low	82 Å²	82	146.5 Å²	146.5	68%	0.678	77%	0.771	S	S	*	*			trans	-57.7	145.6	170.7	0	0	0	0	0	109.1	E9	A7-E9 PolarHBondContact O-N 3.27Å; A7-E9 VanDerWaalsContact O-N 3.16Å
8	P	58.2	Low	58.8	Low	113 Å²	113	144 Å²	144	73%	0.734	76%	0.762	S	S	*	*			trans	-64.6	119.6	-180	25.5	-31.4	0	0	0	109.4	L10	P8-L10 PolarHBondContact O-N 3.06Å; P8-L10 VanDerWaalsContact O-N 3.11Å
9	E	63	Low	58.8	Low	127 Å²	127	140.5 Å²	140.5	59%	0.593	75%	0.751	S	S	*	*			trans	-67.8	105.7	170.9	-78.9	174.8	-168.3	0	0	108.2	R6 A7 N11	R6-E9 IonicContact NE-OE1 3.62Å; R6-E9 IonicContact NH2-OE1 2.74Å; R6-E9 PolarHBondContact NH2-OE1 3.4Å; R6-E9 IonicContact NH2-OE2 3.52Å; R6-E9 IonicContact CZ-OE1 3.55Å; A7-E9 PolarHBondContact O-N 3.27Å; A7-E9 VanDerWaalsContact O-N 3.16Å; E9-N11 PolarHBondContact O-N 2.87Å; E9-N11 VanDerWaalsContact O-N 3.15Å
10	L	62.3	Low	58.7	Low	148 Å²	148	141.3 Å²	141.3	78%	0.775	76%	0.755	S	S	*	*			trans	-79.3	91.2	173.4	-66.3	177	0	0	0	108.5	P8 L12	P8-L10 PolarHBondContact O-N 3.06Å; P8-L10 VanDerWaalsContact O-N 3.11Å; L10-L12 PolarHBondContact O-N 2.85Å
11	N	57.9	Low	58.6	Low	129 Å²	129	138.8 Å²	138.8	69%	0.69	75%	0.748	S	S	*	*			trans	-77.6	103.9	168.5	-63.1	-60.1	0	0	0	107.9	E9	E9-N11 PolarHBondContact O-N 2.87Å; E9-N11 VanDerWaalsContact O-N 3.15Å
12	L	60.5	Low	59.4	Low	143 Å²	143	134 Å²	134	75%	0.749	74%	0.735	S	S	*	*			trans	-90.3	96.8	174.5	-83.9	150.3	0	0	0	108.4	L10 L14	L10-L12 PolarHBondContact O-N 2.85Å; L12-L14 PolarHBondContact O-N 2.85Å
13	D	64.8	Low	60.1	Low	147 Å²	147	137.4 Å²	137.4	79%	0.786	74%	0.743	S	S	*	*			trans	-75.7	104.3	169.5	-69.1	-30.1	0	0	0	108.4	D15	D13-D15 PolarHBondContact O-N 2.96Å
14	L	64.5	Low	60.2	Low	147 Å²	147	133.5 Å²	133.5	77%	0.77	74%	0.737	S	S	*	*			trans	-84.8	99.3	174.9	-72.8	167.4	0	0	0	108.6	L12 L16	L12-L14 PolarHBondContact O-N 2.85Å; L14-L16 VanDerWaalsContact C-N 3.29Å; L14-L16 PolarHBondContact O-N 3.21Å
15	D	64.4	Low	60	Low	157 Å²	157	131.7 Å²	131.7	84%	0.84	74%	0.743	S	S	*	*			trans	-66	92.5	166.4	-77.6	-30.6	0	0	0	108.8	D13 D17	D13-D15 PolarHBondContact O-N 2.96Å; D15-D17 VanDerWaalsContact C-N 3.27Å; D15-D17 PolarHBondContact O-N 3.07Å
16	L	59.8	Low	60.4	Low	138 Å²	138	134.1 Å²	134.1	72%	0.723	75%	0.747	S	S	*	*			trans	-79.8	77.2	-178.4	-153.1	86.1	0	0	0	109.3	L14 V18	L14-L16 VanDerWaalsContact C-N 3.29Å; L14-L16 PolarHBondContact O-N 3.21Å; L16-V18 HydrophobicContact CB-CG2 4.37Å; L16-V18 HydrophobicContact CD2-CG2 3.33Å; L16-V18 HydrophobicContact CG-CG2 3.55Å; L16-V18 PolarHBondContact O-N 3.03Å
17	D	62.7	Low	60.2	Low	145 Å²	145	134 Å²	134	78%	0.775	75%	0.752	S	S	*	*			trans	-72.8	78.3	170.2	-116.4	-24.3	0	0	0	109.3	D15 S19	D15-D17 VanDerWaalsContact C-N 3.27Å; D15-D17 PolarHBondContact O-N 3.07Å; D17-S19 PolarHBondContact O-N 2.91Å
18	V	58.7	Low	60.3	Low	101 Å²	101	133.4 Å²	133.4	61%	0.612	75%	0.753	S	S	*	*			trans	-75.7	64.6	175.1	-172.9	0	0	0	0	109	L16	L16-V18 HydrophobicContact CB-CG2 4.37Å; L16-V18 HydrophobicContact CD2-CG2 3.33Å; L16-V18 HydrophobicContact CG-CG2 3.55Å; L16-V18 PolarHBondContact O-N 3.03Å
19	S	58.7	Low	60.5	Low	78 Å²	78	134 Å²	134	55%	0.545	75%	0.75	S	S	.	*			trans	-129.7	20.1	179.8	67.2	0	0	0	0	113.7	D17	D17-S19 PolarHBondContact O-N 2.91Å
20	N	57.7	Low	60.2	Low	155 Å²	155	134.5 Å²	134.5	83%	0.829	76%	0.757	S	S	*	*			trans	-146.3	56.7	165.4	-78.5	-61.8	0	0	0	112.4	P22	N20-P22 WeakPolarHBondContact O-CD 3.45Å
21	S	57.2	Low	60.1	Low	89 Å²	89	136.7 Å²	136.7	62%	0.622	76%	0.761	S	S	*	*			trans	-69.3	123.8	164.9	-61.5	0	0	0	0	109.2	K23	S21-K23 PolarHBondContact O-N 2.88Å
22	P	57	Low	60.3	Low	128 Å²	128	139.3 Å²	139.3	83%	0.831	77%	0.766	S	S	*	*			trans	-62.4	111.4	177.3	-16.9	28.8	0	0	0	109.6	N20 G24	N20-P22 WeakPolarHBondContact O-CD 3.45Å; P22-G24 VanDerWaalsContact C-N 3.3Å; P22-G24 PolarHBondContact O-N 3.37Å
23	K	62.9	Low	60.5	Low	221 Å²	221	140.5 Å²	140.5	96%	0.961	77%	0.768	S	S	*	*			trans	-70.4	88.5	167.4	-83.3	177.7	174	167.7	0	108.1	S21	S21-K23 PolarHBondContact O-N 2.88Å
24	G	55.2	Low	60.5	Low	64 Å²	64	142 Å²	142	66%	0.66	77%	0.77	S	S	*	*			trans	-166	82.6	-176.5	0	0	0	0	0	114.6	P22	P22-G24 VanDerWaalsContact C-N 3.3Å; P22-G24 PolarHBondContact O-N 3.37Å
25	S	56.1	Low	60.4	Low	122 Å²	122	142.7 Å²	142.7	85%	0.853	78%	0.775	S	S	*	*			trans	38.7	104.9	145.8	-151.3	0	0	0	0	119.9
26	M	66.1	Low	60.5	Low	185 Å²	185	143.2 Å²	143.2	91%	0.911	78%	0.776	S	S	*	*			trans	-33.4	124	158.8	-175.7	156.6	57.1	0	0	115.7
27	K	52.3	Low	61	Low	195 Å²	195	142.3 Å²	142.3	85%	0.848	78%	0.78	S	S	*	*			trans	-140.9	100.1	147.3	-166.2	167.4	-178.9	179.4	0	108.4	N29	K27-N29 PolarHBondContact O-N 2.94Å
28	G	66.2	Low	61.5	Low	69 Å²	69	140.4 Å²	140.4	71%	0.711	78%	0.776	S	S	*	*			trans	-64	126.8	174.3	0	0	0	0	0	110.6
29	N	61.7	Low	62	Low	126 Å²	126	141.6 Å²	141.6	67%	0.674	79%	0.786	S	S	*	*			trans	-168.3	125.6	139.2	50.8	7.4	0	0	0	110.9	K27	K27-N29 PolarHBondContact O-N 2.94Å
30	N	57.5	Low	62.7	Low	137 Å²	137	145.3 Å²	145.3	73%	0.733	80%	0.799	S	S	*	*			trans	61.7	82.1	165.6	-55.8	-62.9	0	0	0	116.2	K32	N30-K32 PolarHBondContact O-N 3.01Å
31	F	60	Low	63.1	Low	195 Å²	195	143.4 Å²	143.4	86%	0.855	80%	0.795	S	S	*	*			trans	-55.6	97.6	144.4	-166.7	-95.4	0	0	0	106.3	E33	F31-E33 VanDerWaalsContact C-N 3.32Å; F31-E33 HydrophobicContact CD1-CG 4.22Å; F31-E33 HydrophobicContact CE1-CG 4.46Å; F31-E33 PolarHBondContact O-N 3.11Å
32	K	62.6	Low	63.7	Low	183 Å²	183	147.8 Å²	147.8	80%	0.796	81%	0.808	S	S	*	*			trans	-69.3	101.1	167.4	-77	-175.5	174.8	-174.6	0	104.9	N30 Q34	N30-K32 PolarHBondContact O-N 3.01Å; K32-Q34 PolarHBondContact O-N 3.01Å
33	E	65.3	Low	64.3	Low	168 Å²	168	150.7 Å²	150.7	79%	0.785	81%	0.81	S	S	*	*			trans	-45.1	119.5	162	-76	171.9	113.9	0	0	106.5	F31 D35	F31-E33 VanDerWaalsContact C-N 3.32Å; F31-E33 HydrophobicContact CD1-CG 4.22Å; F31-E33 HydrophobicContact CE1-CG 4.46Å; F31-E33 PolarHBondContact O-N 3.11Å; E33-D35 PolarHBondContact O-N 3.15Å
34	Q	64.7	Low	64.1	Low	178 Å²	178	143.5 Å²	143.5	83%	0.832	80%	0.798	S	S	*	*			trans	-60.4	129.8	176.4	-65.9	-134.1	-17.3	0	0	107.3	K32 L36	K32-Q34 PolarHBondContact O-N 3.01Å; Q34-L36 PolarHBondContact O-N 3.29Å
35	D	61.3	Low	64.3	Low	163 Å²	163	148.5 Å²	148.5	87%	0.872	81%	0.809	S	S	*	*			trans	-50.2	112.1	176	-74.5	-48.6	0	0	0	108.2	E33 C37	E33-D35 PolarHBondContact O-N 3.15Å; D35-C37 PolarHBondContact O-N 3.23Å
36	L	67.3	Low	64.3	Low	167 Å²	167	146.1 Å²	146.1	87%	0.874	80%	0.804	S	S	*	*			trans	-53.2	121.1	173.8	-70.9	164.2	0	0	0	106.5	Q34	Q34-L36 PolarHBondContact O-N 3.29Å
37	C	69.5	Low	64	Low	119 Å²	119	147.1 Å²	147.1	80%	0.804	80%	0.803	S	S	*	*			trans	-41.6	128.7	179.6	-148.9	0	0	0	0	109.2	D35	D35-C37 PolarHBondContact O-N 3.23Å
38	P	73.9	Confident	64.2	Low	105 Å²	105	141.1 Å²	141.1	68%	0.682	80%	0.797	S	S	*	*	P	Polyproline II helix	trans	-57.4	137	-173.3	21.9	-31.8	0	0	0	109.1	L40	P38-L40 PolarHBondContact O-N 2.83Å
39	P	69.8	Low	63.2	Low	126 Å²	126	144.2 Å²	144.2	82%	0.818	80%	0.802	S	S	*	*	P	Polyproline II helix	trans	-57.4	129.7	-177.3	22.9	-31.9	0	0	0	108.9
40	L	71.6	Confident	62.9	Low	157 Å²	157	143 Å²	143	82%	0.822	80%	0.803	S	S	*	*	P	Polyproline II helix	trans	-55.1	139.1	174.8	-69	170.4	0	0	0	108.8	P38 M42	P38-L40 PolarHBondContact O-N 2.83Å; L40-M42 PolarHBondContact O-N 3.27Å
41	P	68.1	Low	62.9	Low	115 Å²	115	141.2 Å²	141.2	75%	0.747	80%	0.797	S	S	*	*	P	Polyproline II helix	trans	-60.3	116.9	-179.8	23.8	-31.9	0	0	0	108.9	Q43	P41-Q43 PolarHBondContact O-N 2.96Å
42	M	68.1	Low	62.7	Low	181 Å²	181	140.6 Å²	140.6	89%	0.892	79%	0.794	S	S	*	*			trans	-60	110.1	166.8	-75.9	-163	69.3	0	0	107.5	L40 G44	L40-M42 PolarHBondContact O-N 3.27Å; M42-G44 PolarHBondContact O-N 3.16Å
43	Q	70.8	Confident	62.4	Low	189 Å²	189	138.8 Å²	138.8	88%	0.883	79%	0.793	S	S	*	*			trans	-60.7	107.8	169.1	-68.2	-176.3	-7.6	0	0	107	P41 L45	P41-Q43 PolarHBondContact O-N 2.96Å; Q43-L45 PolarHBondContact O-N 3.15Å
44	G	57.9	Low	62	Low	69 Å²	69	142.2 Å²	142.2	71%	0.711	80%	0.799	S	S	*	*			trans	-55.7	126.6	-173.5	0	0	0	0	0	110.8	M42 G46	M42-G44 PolarHBondContact O-N 3.16Å; G44-G46 VanDerWaalsContact C-N 3.27Å; G44-G46 PolarHBondContact O-N 2.89Å
45	L	59.7	Low	61.7	Low	169 Å²	169	145.1 Å²	145.1	89%	0.885	80%	0.802	S	S	*	*			trans	-57.6	97.2	161.1	-174.4	67.6	0	0	0	107.1	Q43 K47	Q43-L45 PolarHBondContact O-N 3.15Å; L45-K47 PolarHBondContact O-N 2.99Å
46	G	56.2	Low	61.6	Low	72 Å²	72	152.8 Å²	152.8	74%	0.742	82%	0.819	S	S	*	*			trans	-57.7	109.3	-177.9	0	0	0	0	0	110	G44 G48	G44-G46 VanDerWaalsContact C-N 3.27Å; G44-G46 PolarHBondContact O-N 2.89Å; G46-G48 PolarHBondContact O-N 2.93Å
47	K	60	Low	61.3	Low	206 Å²	206	152.1 Å²	152.1	90%	0.896	82%	0.816	S	S	*	*			trans	-65.1	118.6	173	-61.9	174.8	-179.4	-177.5	0	108.5	L45	L45-K47 PolarHBondContact O-N 2.99Å
48	G	55.9	Low	60.8	Low	70 Å²	70	153.8 Å²	153.8	72%	0.722	82%	0.817	S	S	*	*			trans	50.5	98.3	152.6	0	0	0	0	0	116.8	G46 S50	G46-G48 PolarHBondContact O-N 2.93Å; G48-S50 PolarHBondContact O-N 3.29Å
49	T	46.4	Very low	60.1	Low	134 Å²	134	156.5 Å²	156.5	82%	0.822	83%	0.825	S	S	*	*			trans	-61.7	99.5	154.6	44.5	0	0	0	0	108.6	V51	T49-V51 VanDerWaalsContact C-N 3.27Å; T49-V51 PolarHBondContact O-N 3.03Å
50	S	54	Low	59.6	Low	99 Å²	99	158.3 Å²	158.3	69%	0.692	83%	0.825	S	S	*	*			trans	-68.1	95.1	156.9	-177.4	0	0	0	0	106.7	G48 K52	G48-S50 PolarHBondContact O-N 3.29Å; S50-K52 VanDerWaalsContact C-N 3.27Å; S50-K52 PolarHBondContact O-N 3.05Å
51	V	57	Low	58.8	Low	101 Å²	101	158.4 Å²	158.4	61%	0.612	83%	0.825	S	S	*	*			trans	-67.8	90.6	170.7	-176.4	0	0	0	0	107.3	T49 N53	T49-V51 VanDerWaalsContact C-N 3.27Å; T49-V51 PolarHBondContact O-N 3.03Å; V51-N53 VanDerWaalsContact C-N 3.34Å; V51-N53 WeakPolarHBondContact CG1-OD1 3.19Å; V51-N53 PolarHBondContact O-N 3.26Å; V51-N53 VanDerWaalsContact O-N 3.15Å
52	K	56.9	Low	58.2	Low	181 Å²	181	161.3 Å²	161.3	79%	0.787	83%	0.83	S	S	*	*			trans	-76.2	93.8	160.3	-72.1	-172.8	-178.3	-178.3	0	107.2	S50 R54	S50-K52 VanDerWaalsContact C-N 3.27Å; S50-K52 PolarHBondContact O-N 3.05Å; K52-R54 PolarHBondContact O-N 2.74Å
53	N	56.8	Low	57.5	Low	145 Å²	145	159.9 Å²	159.9	78%	0.775	83%	0.826	S	S	*	*			trans	-56.6	103.1	167.1	-73.5	-26.7	0	0	0	108.9	V51	V51-N53 VanDerWaalsContact C-N 3.34Å; V51-N53 WeakPolarHBondContact CG1-OD1 3.19Å; V51-N53 PolarHBondContact O-N 3.26Å; V51-N53 VanDerWaalsContact O-N 3.15Å
54	R	55.3	Low	56.5	Low	240 Å²	240	157.6 Å²	157.6	91%	0.906	82%	0.821	S	S	*	*			trans	-90.8	109.8	159	-82.2	-166.6	-80.8	178.9	-4.5	107.4	K52	K52-R54 PolarHBondContact O-N 2.74Å
55	R	58.9	Low	56.3	Low	240 Å²	240	165 Å²	165	91%	0.906	83%	0.831	S	S	*	*			trans	-115.9	131.5	162.3	-174.9	173.2	-75.2	-169	-2.9	106.9
56	W	58.9	Low	56	Low	323 Å²	323	164.6 Å²	164.6	100%	1.223	83%	0.826	S	S	*	*			trans	-62.5	0	-178.4	-63.6	77.1	0	0	0	112.2

Retrieved 56 of 56 residues in 50.4 ms (Link to these results)

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