Q99PV2_RAT Loading...

Syntaxin binding protein 3

AlphaFold DB , UniProt , Accession Q99PV2, Species RAT (Rattus norvegicus, Rat), Gene Stxbp3, Length 593 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M27.2Very low52.6Low239 Ų23984.5 Ų84.5100%1.17746%0.457SS*.  0131.20-79.2169141.500107
2A25.7Very low55.9Low75 Ų7580.3 Ų80.362%0.6244%0.438SS*.PPolyproline II helixtrans-60.8138.8165.100000107.3
3P27.6Very low58.8Low51 Ų5176.3 Ų76.333%0.33142%0.418SS..PPolyproline II helixtrans-56.6150.7176.721.7-30.4000110.2E7P3-E7 HydrophobicContact CB-CB 4.2Å; P3-E7 WeakPolarHBondContact CB-OE2 3.5Å
4P30.4Very low61.4Low80 Ų8070.9 Ų70.952%0.51939%0.388SS..PPolyproline II helixtrans-54.8149.2-179.522.5-31.4000110.6T6 E7P4-T6 PolarHBondContact O-N 3.1Å; P4-E7 PolarHBondContact O-N 2.8Å
5V37.2Very low63.6Low107 Ų10768.8 Ų68.865%0.64837%0.372SS*.Hα-helixtrans-50.1-29.8-177.51780000112E7 R8 G9V5-E7 VanDerWaalsContact C-N 3.27Å; V5-E7 PolarHBondContact O-N 3.17Å; V5-R8 PolarHBondContact O-N 2.75Å; V5-G9 PolarHBondContact O-N 3.13Å
6T41.4Very low65.5Low66 Ų6672.2 Ų72.241%0.40538%0.378SS..Hα-helixtrans-55.3-33.8174.353.60000113.7P4 S12P4-T6 PolarHBondContact O-N 3.1Å; T6-S12 WeakPolarHBondContact O-CB 3.46Å; T6-S12 PolarHBondContact O-OG 3.43Å
7E50.7Low67.2Low111 Ų11170.1 Ų70.152%0.51937%0.365SS..Hα-helixtrans-80.2-16.3178.8-72-174-177.500113.8P3 P4 V5 R16P3-E7 HydrophobicContact CB-CB 4.2Å; P3-E7 WeakPolarHBondContact CB-OE2 3.5Å; P4-E7 PolarHBondContact O-N 2.8Å; V5-E7 VanDerWaalsContact C-N 3.27Å; V5-E7 PolarHBondContact O-N 3.17Å; E7-R16 PolarHBondContact O-NH2 3.39Å
8R64.3Low68.7Low157 Ų15766.2 Ų66.259%0.59235%0.345SS*.Hα-helixtrans-102.6-16.8-174.6-69.3-171.2177.1-158.8-3.6114.9V5V5-R8 PolarHBondContact O-N 2.75Å
9G87.4Confident70.1Confident3 Ų366.4 Ų66.43%0.03134%0.343CS..SBendtrans-67.6161.4-177.700000114.7V5 K11 S12 V13V5-G9 PolarHBondContact O-N 3.13Å; G9-K11 PolarHBondContact O-N 2.91Å; G9-S12 WeakPolarHBondContact O-CB 3.39Å; G9-S12 PolarHBondContact O-N 3.43Å; G9-V13 PolarHBondContact O-N 3.21Å; G9-V13 VanDerWaalsContact O-N 3.09Å
10L93.7Very high71.2Confident3 Ų367.4 Ų67.42%0.01635%0.352CS..Hα-helixtrans-53.2-37.3179.1-173.962000113.2S12 V13 V14 F140 P142 S145 Y148 L188 I561L10-S12 VanDerWaalsContact C-N 3.33Å; L10-S12 PolarHBondContact O-N 3.41Å; L10-V13 PolarHBondContact O-N 3.34Å; L10-V14 WeakPolarHBondContact O-CG2 3.23Å; L10-V14 PolarHBondContact O-N 2.91Å; L10-F140 HydrophobicContact CD1-CE2 4.17Å; L10-F140 HydrophobicContact CD1-CZ 4.23Å; L10-F140 HydrophobicContact CD2-CE2 3.92Å; L10-F140 HydrophobicContact CG-CE2 4.13Å; L10-P142 HydrophobicContact CB-CB 4.44Å; L10-P142 HydrophobicContact CD2-CB 4.16Å; L10-P142 HydrophobicContact CG-CB 3.95Å; L10-S145 WeakPolarHBondContact CB-O 3.47Å; L10-S145 PolarHBondContact N-O 2.68Å; L10-Y148 HydrophobicContact CD2-CD1 4.41Å; L10-Y148 HydrophobicContact CD2-CG 4.45Å; L10-L188 HydrophobicContact CD1-CD2 3.8Å; L10-L188 HydrophobicContact CD1-CG 4.46Å; L10-I561 HydrophobicContact CD2-CG2 4.34Å
11K93.4Very high72.3Confident38 Ų3865.5 Ų65.517%0.16534%0.343CS..Hα-helixtrans-56-46.1173.5-73.7-176.3169.9-176.80112.5G9 V14 W15 S47 C48 P142 H143 E284G9-K11 PolarHBondContact O-N 2.91Å; K11-V14 PolarHBondContact O-N 2.89Å; K11-W15 WeakPolarHBondContact O-CB 3.16Å; K11-W15 PolarHBondContact O-N 3.14Å; K11-S47 WeakPolarHBondContact CD-O 3.34Å; K11-S47 WeakPolarHBondContact CE-O 3.45Å; K11-S47 PolarHBondContact NZ-O 3.38Å; K11-C48 HydrophobicContact CB-CB 4.46Å; K11-P142 WeakPolarHBondContact CE-O 3.47Å; K11-P142 HydrophobicContact CG-CB 3.84Å; K11-P142 HydrophobicContact CG-CG 4.11Å; K11-H143 WeakPolarHBondContact CE-O 3.24Å; K11-H143 PolarHBondContact NZ-O 3.11Å; K11-E284 HydrophobicContact CD-CB 4.34Å; K11-E284 HydrophobicContact CD-CG 4.11Å
12S92.4Very high75.5Confident33 Ų3354.1 Ų54.123%0.23129%0.287CS..Hα-helixtrans-70.5-33.2179-67.90000112.3T6 G9 L10 R16T6-S12 WeakPolarHBondContact O-CB 3.46Å; T6-S12 PolarHBondContact O-OG 3.43Å; G9-S12 WeakPolarHBondContact O-CB 3.39Å; G9-S12 PolarHBondContact O-N 3.43Å; L10-S12 VanDerWaalsContact C-N 3.33Å; L10-S12 PolarHBondContact O-N 3.41Å; S12-R16 WeakPolarHBondContact O-CB 3.45Å; S12-R16 PolarHBondContact O-N 2.87Å
13V93.2Very high78.8Confident29 Ų2950.7 Ų50.718%0.17626%0.258CS..Hα-helixtrans-63-48.6171.2177.70000111.1G9 L10 R16 K17 T187G9-V13 PolarHBondContact O-N 3.21Å; G9-V13 VanDerWaalsContact O-N 3.09Å; L10-V13 PolarHBondContact O-N 3.34Å; V13-R16 PolarHBondContact O-N 3.09Å; V13-K17 WeakPolarHBondContact O-CB 3.48Å; V13-K17 PolarHBondContact O-N 3.48Å; V13-T187 HydrophobicContact CG1-CG2 4.02Å; V13-T187 WeakPolarHBondContact CG1-O 3.41Å
14V95.3Very high81.9Confident0 Ų051.5 Ų51.50%026%0.26CS..Hα-helixtrans-62.5-48.8178170.10000111.2L10 K11 R16 K17 I18 L44 C48 I138 F140 P142 T187L10-V14 WeakPolarHBondContact O-CG2 3.23Å; L10-V14 PolarHBondContact O-N 2.91Å; K11-V14 PolarHBondContact O-N 2.89Å; V14-R16 PolarHBondContact O-N 2.96Å; V14-K17 PolarHBondContact O-N 3.35Å; V14-I18 HydrophobicContact CG1-CD1 3.89Å; V14-I18 HydrophobicContact CG1-CG1 4.49Å; V14-I18 WeakPolarHBondContact O-CG1 3.45Å; V14-I18 PolarHBondContact O-N 2.79Å; V14-L44 HydrophobicContact CG1-CD1 3.82Å; V14-C48 HydrophobicContact CG1-CB 4.47Å; V14-I138 HydrophobicContact CG1-CG2 4.18Å; V14-F140 HydrophobicContact CG2-CE2 3.82Å; V14-F140 HydrophobicContact CG2-CZ 3.6Å; V14-P142 HydrophobicContact CB-CG 4.08Å; V14-P142 HydrophobicContact CG1-CG 4.14Å; V14-P142 HydrophobicContact CG2-CB 4.19Å; V14-P142 HydrophobicContact CG2-CG 3.95Å; V14-T187 HydrophobicContact CG2-CG2 3.99Å
15W94.5Very high84.9Confident40 Ų4050.1 Ų50.115%0.15225%0.248CC..Hα-helixtrans-58.8-46.4178.3173.7-126.4000111.9K11 K17 I18 K19 F23 L45 C48 C49 D53 L54 E57K11-W15 WeakPolarHBondContact O-CB 3.16Å; K11-W15 PolarHBondContact O-N 3.14Å; W15-K17 VanDerWaalsContact C-N 3.32Å; W15-K17 PolarHBondContact O-N 3.31Å; W15-I18 HydrophobicContact CZ3-CG2 4.38Å; W15-I18 PolarHBondContact O-N 3.29Å; W15-K19 WeakPolarHBondContact O-CB 3.42Å; W15-K19 PolarHBondContact O-N 3.38Å; W15-F23 HydrophobicContact CH2-CD2 4.06Å; W15-F23 AromaticContact CH2-CE2 3.63Å; W15-F23 HydrophobicContact CH2-CE2 3.63Å; W15-F23 HydrophobicContact CZ3-CD2 4.31Å; W15-F23 AromaticContact CZ3-CE2 3.62Å; W15-F23 HydrophobicContact CZ3-CE2 3.62Å; W15-L45 HydrophobicContact CZ3-CD2 4.43Å; W15-C48 HydrophobicContact CB-CB 4.15Å; W15-C49 HydrophobicContact CD2-CB 3.8Å; W15-C49 HydrophobicContact CE3-CB 3.46Å; W15-C49 VanDerWaalsContact CE3-CB 3.46Å; W15-C49 HydrophobicContact CH2-CB 3.88Å; W15-C49 HydrophobicContact CZ2-CB 4.19Å; W15-C49 HydrophobicContact CZ3-CB 3.49Å; W15-C49 VanDerWaalsContact CZ3-CB 3.49Å; W15-C49 VanDerWaalsContact CZ3-SG 3.59Å; W15-D53 HydrophobicContact CH2-CB 4.22Å; W15-D53 HydrophobicContact CZ2-CB 3.75Å; W15-L54 HydrophobicContact CH2-CD2 4.02Å; W15-L54 HydrophobicContact CZ3-CD2 4.17Å; W15-E57 HydrophobicContact CH2-CG 4.39Å; W15-E57 HydrophobicContact CZ2-CG 4.43Å
16R93.6Very high87.5Confident123 Ų12345.2 Ų45.246%0.46422%0.218SC..Hα-helixtrans-59.7-43176.7-171.8-174.9-53.6102.53.6111.6E7 S12 V13 V14 K19 T20E7-R16 PolarHBondContact O-NH2 3.39Å; S12-R16 WeakPolarHBondContact O-CB 3.45Å; S12-R16 PolarHBondContact O-N 2.87Å; V13-R16 PolarHBondContact O-N 3.09Å; V14-R16 PolarHBondContact O-N 2.96Å; R16-K19 PolarHBondContact O-N 2.88Å; R16-T20 PolarHBondContact O-N 3.47Å; R16-T20 PolarHBondContact O-OG1 3.39Å; R16-T20 VanDerWaalsContact O-OG1 3.04Å
17K93.9Very high89.7Confident37 Ų3749.4 Ų49.416%0.16123%0.227CC..Hα-helixtrans-60.8-50.8176.6-172.5173.3168.8-1780110.5V13 V14 W15 K19 T20 T21 I136 N137 I138 T187V13-K17 WeakPolarHBondContact O-CB 3.48Å; V13-K17 PolarHBondContact O-N 3.48Å; V14-K17 PolarHBondContact O-N 3.35Å; W15-K17 VanDerWaalsContact C-N 3.32Å; W15-K17 PolarHBondContact O-N 3.31Å; K17-K19 VanDerWaalsContact C-N 3.31Å; K17-K19 PolarHBondContact O-N 3.25Å; K17-T20 PolarHBondContact O-N 2.99Å; K17-T21 HydrophobicContact CG-CG2 4.22Å; K17-T21 WeakPolarHBondContact O-CB 3.27Å; K17-T21 WeakPolarHBondContact O-CG2 3.24Å; K17-T21 PolarHBondContact O-N 3.41Å; K17-T21 PolarHBondContact O-OG1 2.96Å; K17-I136 WeakPolarHBondContact CE-O 3.25Å; K17-I136 HydrophobicContact CG-CG2 4.49Å; K17-I136 PolarHBondContact NZ-O 3.47Å; K17-I136 VanDerWaalsContact NZ-O 3.14Å; K17-N137 PolarHBondContact NZ-O 3.15Å; K17-I138 HydrophobicContact CB-CD1 4.13Å; K17-I138 HydrophobicContact CD-CD1 3.72Å; K17-I138 HydrophobicContact CD-CG1 3.84Å; K17-I138 HydrophobicContact CG-CD1 3.87Å; K17-T187 HydrophobicContact CD-CG2 3.92Å; K17-T187 PolarHBondContact NZ-OG1 3.32Å
18I95.1Very high91.4Very high0 Ų049.8 Ų49.80%023%0.227CC..Hα-helixtrans-56-46.6176.6-66.6171.5000110.6V14 W15 T20 T21 V22 F23 L44 L45 F80 I138V14-I18 HydrophobicContact CG1-CD1 3.89Å; V14-I18 HydrophobicContact CG1-CG1 4.49Å; V14-I18 WeakPolarHBondContact O-CG1 3.45Å; V14-I18 PolarHBondContact O-N 2.79Å; W15-I18 HydrophobicContact CZ3-CG2 4.38Å; W15-I18 PolarHBondContact O-N 3.29Å; I18-T20 PolarHBondContact O-N 2.91Å; I18-T21 PolarHBondContact O-N 3.5Å; I18-V22 HydrophobicContact CG2-CB 4.34Å; I18-V22 HydrophobicContact CG2-CG2 4.1Å; I18-V22 WeakPolarHBondContact O-CA 3.38Å; I18-V22 WeakPolarHBondContact O-CB 3.47Å; I18-V22 WeakPolarHBondContact O-CG2 3.21Å; I18-V22 PolarHBondContact O-N 2.76Å; I18-F23 HydrophobicContact CG2-CD2 4.25Å; I18-F23 HydrophobicContact CG2-CE2 3.75Å; I18-L44 HydrophobicContact CD1-CD2 4.32Å; I18-L44 HydrophobicContact CD1-CG 4.27Å; I18-L45 HydrophobicContact CD1-CD2 3.99Å; I18-L45 HydrophobicContact CG2-CD2 4.2Å; I18-F80 HydrophobicContact CD1-CE1 4.19Å; I18-F80 HydrophobicContact CD1-CZ 4.21Å; I18-F80 HydrophobicContact CG1-CZ 4.33Å; I18-I138 HydrophobicContact CD1-CD1 4.48Å; I18-I138 HydrophobicContact CG1-CD1 3.72Å
19K94.4Very high92.4Very high70 Ų7051.5 Ų51.530%0.30424%0.242SC..Iπ-helixtrans-55.6-54.6177.4-175.6172.5175.5147.50112.5W15 R16 K17 T21 F23 D24 E57W15-K19 WeakPolarHBondContact O-CB 3.42Å; W15-K19 PolarHBondContact O-N 3.38Å; R16-K19 PolarHBondContact O-N 2.88Å; K17-K19 VanDerWaalsContact C-N 3.31Å; K17-K19 PolarHBondContact O-N 3.25Å; K19-T21 PolarHBondContact O-N 3.18Å; K19-F23 PolarHBondContact O-N 3.03Å; K19-F23 VanDerWaalsContact O-N 3.11Å; K19-D24 PolarHBondContact O-N 3.5Å; K19-E57 WeakPolarHBondContact CE-OE1 3.29Å; K19-E57 IonicContact NZ-OE1 3.97Å; K19-E57 PolarHBondContact NZ-OE1 3.19Å
20T93.5Very high92.3Very high85 Ų8555.2 Ų55.252%0.52128%0.279SS..Iπ-helixtrans-66.5-39.3-178-53.70000112.4R16 K17 I18R16-T20 PolarHBondContact O-N 3.47Å; R16-T20 PolarHBondContact O-OG1 3.39Å; R16-T20 VanDerWaalsContact O-OG1 3.04Å; K17-T20 PolarHBondContact O-N 2.99Å; I18-T20 PolarHBondContact O-N 2.91Å
21T93.2Very high92.1Very high28 Ų2857.3 Ų57.317%0.17229%0.289CS..Iπ-helixtrans-89.4-23.4-172.662.10000114.3K17 I18 K19 D25 Y109 I136K17-T21 HydrophobicContact CG-CG2 4.22Å; K17-T21 WeakPolarHBondContact O-CB 3.27Å; K17-T21 WeakPolarHBondContact O-CG2 3.24Å; K17-T21 PolarHBondContact O-N 3.41Å; K17-T21 PolarHBondContact O-OG1 2.96Å; I18-T21 PolarHBondContact O-N 3.5Å; K19-T21 PolarHBondContact O-N 3.18Å; T21-D25 WeakPolarHBondContact O-CB 3.21Å; T21-Y109 VanDerWaalsContact O-CE1 3.28Å; T21-Y109 WeakPolarHBondContact O-CE1 3.36Å; T21-I136 HydrophobicContact CG2-CG2 4.42Å; T21-I136 VanDerWaalsContact OG1-CG2 3.28Å; T21-I136 WeakPolarHBondContact OG1-CG2 3.46Å
22V94.8Very high92.1Very high0 Ų062 Ų620%031%0.306CS..Iπ-helixtrans-110-64.5-176.5-175.10000110.8I18 C26 L78 Y109 I136I18-V22 HydrophobicContact CG2-CB 4.34Å; I18-V22 HydrophobicContact CG2-CG2 4.1Å; I18-V22 WeakPolarHBondContact O-CA 3.38Å; I18-V22 WeakPolarHBondContact O-CB 3.47Å; I18-V22 WeakPolarHBondContact O-CG2 3.21Å; I18-V22 PolarHBondContact O-N 2.76Å; V22-C26 PolarHBondContact O-N 3.11Å; V22-C26 PolarHBondContact O-SG 3.4Å; V22-L78 HydrophobicContact CG1-CD1 3.86Å; V22-L78 HydrophobicContact CG1-CD2 3.99Å; V22-L78 HydrophobicContact CG1-CG 4.38Å; V22-Y109 HydrophobicContact CG1-CD2 3.77Å; V22-Y109 HydrophobicContact CG1-CE2 3.98Å; V22-Y109 HydrophobicContact CG1-CG 4.04Å; V22-Y109 HydrophobicContact CG2-CD1 4.16Å; V22-Y109 HydrophobicContact CG2-CG 4.15Å; V22-I136 HydrophobicContact CG2-CD1 3.23Å; V22-I136 HydrophobicContact CG2-CG1 4.37Å
23F93.8Very high92.3Very high4 Ų460.7 Ų60.72%0.01830%0.296CS..Iπ-helixtrans-71.1-48.7-168.7-65.8-58.3000110.8W15 I18 K19 D25 C26 R27 M35 L54 E57 V59 L78W15-F23 HydrophobicContact CH2-CD2 4.06Å; W15-F23 AromaticContact CH2-CE2 3.63Å; W15-F23 HydrophobicContact CH2-CE2 3.63Å; W15-F23 HydrophobicContact CZ3-CD2 4.31Å; W15-F23 AromaticContact CZ3-CE2 3.62Å; W15-F23 HydrophobicContact CZ3-CE2 3.62Å; I18-F23 HydrophobicContact CG2-CD2 4.25Å; I18-F23 HydrophobicContact CG2-CE2 3.75Å; K19-F23 PolarHBondContact O-N 3.03Å; K19-F23 VanDerWaalsContact O-N 3.11Å; F23-D25 PolarHBondContact O-N 3.08Å; F23-C26 PolarHBondContact O-N 3.45Å; F23-R27 WeakPolarHBondContact O-CA 3.35Å; F23-R27 WeakPolarHBondContact O-CB 3.45Å; F23-R27 PolarHBondContact O-N 2.93Å; F23-M35 HydrophobicContact CE1-CE 4.07Å; F23-M35 HydrophobicContact CE1-SD 4.29Å; F23-M35 HydrophobicContact CZ-CE 3.72Å; F23-M35 HydrophobicContact CZ-SD 4.12Å; F23-L54 HydrophobicContact CE1-CD2 4.34Å; F23-L54 HydrophobicContact CE2-CD2 3.95Å; F23-L54 HydrophobicContact CZ-CD2 3.47Å; F23-L54 VanDerWaalsContact CZ-CD2 3.47Å; F23-E57 HydrophobicContact CB-CB 4.02Å; F23-E57 HydrophobicContact CB-CG 4.11Å; F23-E57 HydrophobicContact CD1-CB 3.8Å; F23-E57 HydrophobicContact CD1-CG 4.46Å; F23-E57 HydrophobicContact CD2-CB 4.17Å; F23-E57 HydrophobicContact CD2-CG 3.94Å; F23-E57 HydrophobicContact CE1-CB 4.34Å; F23-E57 HydrophobicContact CG-CB 3.73Å; F23-E57 HydrophobicContact CG-CG 3.92Å; F23-V59 HydrophobicContact CD1-CG2 4.39Å; F23-V59 HydrophobicContact CE1-CG2 3.7Å; F23-L78 HydrophobicContact CD1-CD2 4.05Å; F23-L78 HydrophobicContact CE1-CD2 3.63Å
24D93.8Very high92.4Very high68 Ų6859.6 Ų59.636%0.36429%0.289SS..Hα-helixtrans-65.1-37.3178.1-70.7-30.6000112.5K19 C26 R27K19-D24 PolarHBondContact O-N 3.5Å; D24-C26 VanDerWaalsContact C-N 3.33Å; D24-C26 PolarHBondContact O-N 3.34Å; D24-R27 WeakPolarHBondContact O-CB 3.26Å; D24-R27 PolarHBondContact O-N 3.33Å; D24-R27 IonicContact OD1-NH1 3.8Å
25D92.9Very high92.5Very high50 Ų5059.6 Ų59.627%0.26729%0.289SS..Hα-helixtrans-67.3-31.7179.3-178.760.8000113.2T21 F23 Y109 R132T21-D25 WeakPolarHBondContact O-CB 3.21Å; F23-D25 PolarHBondContact O-N 3.08Å; D25-Y109 HydrophobicContact CB-CE1 4.48Å; D25-Y109 PolarHBondContact OD2-OH 3.25Å; D25-R132 IonicContact OD1-CZ 3.83Å; D25-R132 IonicContact OD1-NH2 3.81Å; D25-R132 IonicContact OD2-NE 2.8Å
26C91.4Very high92.6Very high4 Ų457.7 Ų57.73%0.02728%0.282CS..Hα-helixtrans-100.5317880.10000114V22 F23 D24 K28 K33 Y107 Y109V22-C26 PolarHBondContact O-N 3.11Å; V22-C26 PolarHBondContact O-SG 3.4Å; F23-C26 PolarHBondContact O-N 3.45Å; D24-C26 VanDerWaalsContact C-N 3.33Å; D24-C26 PolarHBondContact O-N 3.34Å; C26-K28 PolarHBondContact O-N 3.36Å; C26-K33 WeakPolarHBondContact O-CE 3.42Å; C26-K33 PolarHBondContact O-NZ 3.44Å; C26-Y107 HydrophobicContact CB-CD1 3.67Å; C26-Y107 HydrophobicContact CB-CE1 3.92Å; C26-Y107 HydrophobicContact CB-CG 4.05Å; C26-Y109 HydrophobicContact CB-CE2 4.33Å; C26-Y109 WeakPolarHBondContact CB-OH 3.5Å
27R88.2Confident92.8Very high155 Ų15552 Ų5259%0.58526%0.261SS*.  trans-65.3132.8-173.3-165169-179.6170.71.2111.5F23 D24F23-R27 WeakPolarHBondContact O-CA 3.35Å; F23-R27 WeakPolarHBondContact O-CB 3.45Å; F23-R27 PolarHBondContact O-N 2.93Å; D24-R27 WeakPolarHBondContact O-CB 3.26Å; D24-R27 PolarHBondContact O-N 3.33Å; D24-R27 IonicContact OD1-NH1 3.8Å
28K87.6Confident93Very high119 Ų11950.4 Ų50.452%0.51725%0.254SS..  trans-144.7124.4172.2-70.8-166.1174.4-1600108C26 G30 E31C26-K28 PolarHBondContact O-N 3.36Å; K28-G30 PolarHBondContact O-N 3.26Å; K28-E31 HydrophobicContact CB-CB 3.88Å; K28-E31 PolarHBondContact O-N 3.31Å; K28-E31 VanDerWaalsContact O-N 3.12Å
29E84.2Confident93Very high193 Ų19353.7 Ų53.790%0.90227%0.271SS*.THydrogen-bonded Turntrans-56133.8-179.6-68.6-176.5170.600111E31E29-E31 PolarHBondContact O-N 3.23Å
30G84.7Confident93Very high80 Ų8051.6 Ų51.683%0.82526%0.263SS*.THydrogen-bonded Turntrans72.2-1.2-178.800000116K28K28-G30 PolarHBondContact O-N 3.26Å
31E90.5Very high93.2Very high48 Ų4847.6 Ų47.622%0.22424%0.238CC..  trans-98.8102.3-178.4-174.6171.5-10300112.8K28 E29 K33 K76K28-E31 HydrophobicContact CB-CB 3.88Å; K28-E31 PolarHBondContact O-N 3.31Å; K28-E31 VanDerWaalsContact O-N 3.12Å; E29-E31 PolarHBondContact O-N 3.23Å; E31-K33 PolarHBondContact O-NZ 3.38Å; E31-K33 VanDerWaalsContact O-NZ 3.11Å; E31-K76 WeakPolarHBondContact OE1-CE 3.47Å; E31-K76 IonicContact OE1-NZ 2.63Å; E31-K76 PolarHBondContact OE1-NZ 2.94Å; E31-K76 IonicContact OE2-NZ 2.97Å; E31-K76 PolarHBondContact OE2-NZ 3.28Å
32W93.5Very high93.3Very high136 Ų13649 Ų4952%0.51525%0.246SC..  trans-72.4143.1169.3-65.8107.7000112.6L55 G58 T60 M75W32-L55 WeakPolarHBondContact CZ3-O 3.26Å; W32-G58 WeakPolarHBondContact CA-O 3.39Å; W32-T60 HydrophobicContact CB-CG2 3.71Å; W32-T60 HydrophobicContact CD2-CG2 3.51Å; W32-T60 HydrophobicContact CE3-CG2 3.26Å; W32-T60 HydrophobicContact CG-CG2 3.73Å; W32-T60 HydrophobicContact CZ3-CG2 4.05Å; W32-M75 VanDerWaalsContact C-CE 3.46Å; W32-M75 HydrophobicContact CB-CE 3.65Å; W32-M75 WeakPolarHBondContact O-CE 3.23Å
33K95.3Very high93.3Very high6 Ų654 Ų543%0.02627%0.265CS..EExtended strand (participates in β ladder)trans-130.4152-178.2-57.3176.5-164.7690111C26 E31 G58 V59 T60 Y107C26-K33 WeakPolarHBondContact O-CE 3.42Å; C26-K33 PolarHBondContact O-NZ 3.44Å; E31-K33 PolarHBondContact O-NZ 3.38Å; E31-K33 VanDerWaalsContact O-NZ 3.11Å; K33-G58 PolarHBondContact N-O 2.86Å; K33-V59 WeakPolarHBondContact O-CA 3.46Å; K33-T60 PolarHBondContact O-N 3.26Å; K33-T60 PolarHBondContact O-OG1 3.16Å; K33-Y107 HydrophobicContact CD-CD2 4.45Å; K33-Y107 HydrophobicContact CD-CE2 4.34Å
34I95.7Very high93.4Very high5 Ų553.9 Ų53.93%0.02627%0.265CS..EExtended strand (participates in β ladder)trans-95.3129.7168.8-57.1174.8000107.1L36 V61 V72 M75 K76 A77 L78 Y103I34-L36 HydrophobicContact CB-CD2 4.33Å; I34-L36 HydrophobicContact CG2-CD2 3.91Å; I34-L36 WeakPolarHBondContact O-CD2 3.3Å; I34-V61 HydrophobicContact CG2-CB 4.28Å; I34-V72 HydrophobicContact CD1-CB 3.57Å; I34-V72 HydrophobicContact CD1-CG1 3.85Å; I34-V72 HydrophobicContact CD1-CG2 3.73Å; I34-M75 HydrophobicContact CD1-CB 4.15Å; I34-M75 HydrophobicContact CD1-SD 4.07Å; I34-M75 HydrophobicContact CG1-CB 4.29Å; I34-M75 HydrophobicContact CG1-CE 3.99Å; I34-M75 HydrophobicContact CG1-SD 3.94Å; I34-K76 PolarHBondContact N-O 2.98Å; I34-K76 VanDerWaalsContact N-O 3.12Å; I34-A77 CarbonylContact O-C 3.53Å; I34-A77 WeakPolarHBondContact O-CA 3.41Å; I34-L78 PolarHBondContact O-N 3.17Å; I34-Y103 HydrophobicContact CD1-CD1 4.28Å; I34-Y103 HydrophobicContact CD1-CE1 3.98Å
35M97Very high93.4Very high0 Ų050.9 Ų50.90%025%0.249CC..EExtended strand (participates in β ladder)trans-99.3131.8179.1-168.8175.4-159.100110.8F23 L37 L45 L54 V59 V61 I62 E63 L78 F80F23-M35 HydrophobicContact CE1-CE 4.07Å; F23-M35 HydrophobicContact CE1-SD 4.29Å; F23-M35 HydrophobicContact CZ-CE 3.72Å; F23-M35 HydrophobicContact CZ-SD 4.12Å; M35-L37 HydrophobicContact CE-CD2 3.82Å; M35-L37 HydrophobicContact CG-CD2 3.86Å; M35-L37 HydrophobicContact CG-CG 4.32Å; M35-L37 HydrophobicContact SD-CD2 4.06Å; M35-L45 HydrophobicContact CE-CD1 3.46Å; M35-L45 VanDerWaalsContact CE-CD1 3.46Å; M35-L45 HydrophobicContact SD-CD1 3.75Å; M35-L54 HydrophobicContact SD-CD2 4.35Å; M35-V59 HydrophobicContact CB-CG1 3.5Å; M35-V59 VanDerWaalsContact CB-CG1 3.5Å; M35-V59 HydrophobicContact CB-CG2 4.26Å; M35-V59 HydrophobicContact SD-CG1 4.43Å; M35-V59 HydrophobicContact SD-CG2 4.3Å; M35-V61 PolarHBondContact N-O 2.92Å; M35-I62 HydrophobicContact CB-CG1 4.47Å; M35-I62 CarbonylContact O-C 3.55Å; M35-I62 WeakPolarHBondContact O-CA 3.35Å; M35-E63 PolarHBondContact O-N 3.47Å; M35-L78 CarbonylContact C-O 3.14Å; M35-L78 WeakPolarHBondContact CA-O 3.45Å; M35-L78 HydrophobicContact CE-CD2 4.06Å; M35-L78 HydrophobicContact CG-CD2 4.2Å; M35-L78 HydrophobicContact CG-CG 4.37Å; M35-L78 HydrophobicContact SD-CD2 4.4Å; M35-F80 HydrophobicContact CE-CB 3.76Å; M35-F80 HydrophobicContact CE-CD1 3.99Å; M35-F80 HydrophobicContact CE-CG 4.26Å
36L98Very high93.3Very high0 Ų052.8 Ų52.80%027%0.266CS..EExtended strand (participates in β ladder)trans-116.8121-176.3-69.4-59.1000108I34 E63 A77 L78 Y79 F80 Y103I34-L36 HydrophobicContact CB-CD2 4.33Å; I34-L36 HydrophobicContact CG2-CD2 3.91Å; I34-L36 WeakPolarHBondContact O-CD2 3.3Å; L36-E63 WeakPolarHBondContact CA-O 3.41Å; L36-E63 HydrophobicContact CD1-CB 3.91Å; L36-A77 HydrophobicContact CD2-CB 3.59Å; L36-L78 PolarHBondContact N-O 3.45Å; L36-Y79 HydrophobicContact CB-CD1 3.57Å; L36-Y79 HydrophobicContact CB-CE1 3.8Å; L36-Y79 HydrophobicContact CB-CG 4.16Å; L36-Y79 HydrophobicContact CG-CD1 4.03Å; L36-Y79 HydrophobicContact CG-CE1 3.73Å; L36-F80 PolarHBondContact O-N 3.28Å; L36-Y103 HydrophobicContact CD2-CE2 4.43Å
37L97.9Very high93.4Very high4 Ų453.5 Ų53.52%0.02127%0.271CS..EExtended strand (participates in β ladder)trans-121.1147.7-175.7-54.7179.3000110.3M35 T42 L45 I62 E63 N64 I65 F80M35-L37 HydrophobicContact CE-CD2 3.82Å; M35-L37 HydrophobicContact CG-CD2 3.86Å; M35-L37 HydrophobicContact CG-CG 4.32Å; M35-L37 HydrophobicContact SD-CD2 4.06Å; L37-T42 WeakPolarHBondContact CB-OG1 3.47Å; L37-L45 HydrophobicContact CD1-CD1 3.68Å; L37-L45 HydrophobicContact CD2-CD1 3.65Å; L37-L45 HydrophobicContact CG-CD1 4.32Å; L37-I62 HydrophobicContact CD1-CG2 3.39Å; L37-I62 HydrophobicContact CG-CG2 3.92Å; L37-E63 PolarHBondContact N-O 2.89Å; L37-N64 CarbonylContact O-C 3.54Å; L37-N64 WeakPolarHBondContact O-CA 3.5Å; L37-I65 PolarHBondContact O-N 3.22Å; L37-F80 HydrophobicContact CD2-CB 3.95Å; L37-F80 HydrophobicContact CD2-CD1 4.08Å; L37-F80 HydrophobicContact CD2-CG 4.49Å
38D97.3Very high93.5Very high3 Ų347 Ų472%0.01625%0.249CC..  trans-90.2-178.7159.968.111.1000111.2F40 T41 T42 I65 Y66 I81 S82 S87D38-F40 VanDerWaalsContact C-N 3.3Å; D38-F40 PolarHBondContact O-N 3.34Å; D38-F40 PolarHBondContact OD1-N 2.85Å; D38-T41 PolarHBondContact N-OG1 2.68Å; D38-T41 PolarHBondContact O-OG1 3.25Å; D38-T41 WeakPolarHBondContact OD1-CB 3.31Å; D38-T41 WeakPolarHBondContact OD1-CG2 3.26Å; D38-T41 PolarHBondContact OD1-N 2.91Å; D38-T41 PolarHBondContact OD1-OG1 2.92Å; D38-T42 VanDerWaalsContact O-CB 3.29Å; D38-T42 WeakPolarHBondContact O-CB 3.41Å; D38-T42 PolarHBondContact O-N 2.75Å; D38-T42 PolarHBondContact O-OG1 3.35Å; D38-I65 HydrophobicContact CB-CG2 3.92Å; D38-Y66 HydrophobicContact CB-CE2 4.01Å; D38-I81 HydrophobicContact CB-CG2 4.38Å; D38-S82 WeakPolarHBondContact OD2-CA 3.01Å; D38-S82 WeakPolarHBondContact OD2-CB 3.26Å; D38-S82 PolarHBondContact OD2-N 3.04Å; D38-S82 PolarHBondContact OD2-OG 2.61Å; D38-S87 PolarHBondContact OD2-OG 2.86Å
39D95.5Very high93.6Very high69 Ų6942.1 Ų42.137%0.36923%0.23SC..Hα-helixtrans-64.7-36.6-174.4-58.8-29.8000111.8R43 N64 Y66D39-R43 PolarHBondContact O-N 3.4Å; D39-R43 PolarHBondContact O-NH1 3.02Å; D39-N64 PolarHBondContact OD1-ND2 3.44Å; D39-Y66 WeakPolarHBondContact OD2-CE2 3.31Å
40F95.3Very high93.8Very high27 Ų2737.4 Ų37.412%0.11821%0.206CC..Hα-helixtrans-68.7-52.4177.9170.5-99000111.5D38 T42 R43 L44 S82 T111 I141D38-F40 VanDerWaalsContact C-N 3.3Å; D38-F40 PolarHBondContact O-N 3.34Å; D38-F40 PolarHBondContact OD1-N 2.85Å; F40-T42 VanDerWaalsContact C-N 3.26Å; F40-T42 PolarHBondContact O-N 3.2Å; F40-R43 WeakPolarHBondContact O-CB 3.39Å; F40-R43 PolarHBondContact O-N 3.3Å; F40-L44 HydrophobicContact CE1-CD2 4.07Å; F40-L44 HydrophobicContact CZ-CD2 4.41Å; F40-L44 PolarHBondContact O-N 3.11Å; F40-S82 WeakPolarHBondContact CD1-OG 3.37Å; F40-T111 HydrophobicContact CD1-CG2 3.98Å; F40-T111 HydrophobicContact CE1-CG2 3.79Å; F40-I141 HydrophobicContact CD2-CD1 4Å; F40-I141 HydrophobicContact CE2-CD1 3.5Å; F40-I141 VanDerWaalsContact CE2-CD1 3.5Å; F40-I141 HydrophobicContact CE2-CG1 3.99Å; F40-I141 HydrophobicContact CZ-CD1 3.99Å
41T96.6Very high94Very high0 Ų037.6 Ų37.60%019%0.187CC..Hα-helixtrans-65.4-29.4-179.749.40000112.9D38 L44 L45 F80 T111D38-T41 PolarHBondContact N-OG1 2.68Å; D38-T41 PolarHBondContact O-OG1 3.25Å; D38-T41 WeakPolarHBondContact OD1-CB 3.31Å; D38-T41 WeakPolarHBondContact OD1-CG2 3.26Å; D38-T41 PolarHBondContact OD1-N 2.91Å; D38-T41 PolarHBondContact OD1-OG1 2.92Å; T41-L44 PolarHBondContact O-N 2.88Å; T41-L45 PolarHBondContact O-N 3.33Å; T41-F80 WeakPolarHBondContact CB-O 3.4Å; T41-F80 HydrophobicContact CG2-CD1 3.96Å; T41-F80 HydrophobicContact CG2-CD2 4.38Å; T41-F80 HydrophobicContact CG2-CE1 4.03Å; T41-F80 HydrophobicContact CG2-CE2 4.41Å; T41-F80 HydrophobicContact CG2-CG 4.15Å; T41-F80 HydrophobicContact CG2-CZ 4.26Å; T41-F80 WeakPolarHBondContact CG2-O 3.31Å; T41-F80 PolarHBondContact OG1-O 3.48Å; T41-T111 HydrophobicContact CG2-CG2 3.29Å
42T95.9Very high94Very high57 Ų5739 Ų3935%0.3520%0.199SC..Hα-helixtrans-60.4-48.7169.1-58.90000111L37 D38 F40 S46L37-T42 WeakPolarHBondContact CB-OG1 3.47Å; D38-T42 VanDerWaalsContact O-CB 3.29Å; D38-T42 WeakPolarHBondContact O-CB 3.41Å; D38-T42 PolarHBondContact O-N 2.75Å; D38-T42 PolarHBondContact O-OG1 3.35Å; F40-T42 VanDerWaalsContact C-N 3.26Å; F40-T42 PolarHBondContact O-N 3.2Å; T42-S46 WeakPolarHBondContact O-CB 3.3Å; T42-S46 PolarHBondContact O-N 3.03Å; T42-S46 PolarHBondContact O-OG 3.41Å
43R94.2Very high93.9Very high107 Ų10734.5 Ų34.540%0.40419%0.185SC..Hα-helixtrans-63.2-45.9176.4-71.3-170.4-65.4-79.48.8111.4D39 F40 L45 S46 S47 I141 D151D39-R43 PolarHBondContact O-N 3.4Å; D39-R43 PolarHBondContact O-NH1 3.02Å; F40-R43 WeakPolarHBondContact O-CB 3.39Å; F40-R43 PolarHBondContact O-N 3.3Å; R43-L45 PolarHBondContact O-N 3.19Å; R43-S46 WeakPolarHBondContact CA-OG 3.3Å; R43-S46 PolarHBondContact O-N 3.15Å; R43-S46 PolarHBondContact O-OG 3.31Å; R43-S47 PolarHBondContact O-N 2.81Å; R43-I141 HydrophobicContact CB-CD1 4.18Å; R43-D151 IonicContact CZ-OD2 2.81Å; R43-D151 IonicContact NE-OD2 3.75Å; R43-D151 PolarHBondContact NE-OD2 2.87Å; R43-D151 IonicContact NH2-OD2 3.16Å; R43-D151 PolarHBondContact NH2-OD2 3.27Å
44L95.7Very high93.7Very high0 Ų034.5 Ų34.50%019%0.185CC..Hα-helixtrans-55.7-51.8178.3177.956.9000111.8V14 I18 F40 T41 S47 C48 F80 I138 F140 I141 P142V14-L44 HydrophobicContact CG1-CD1 3.82Å; I18-L44 HydrophobicContact CD1-CD2 4.32Å; I18-L44 HydrophobicContact CD1-CG 4.27Å; F40-L44 HydrophobicContact CE1-CD2 4.07Å; F40-L44 HydrophobicContact CZ-CD2 4.41Å; F40-L44 PolarHBondContact O-N 3.11Å; T41-L44 PolarHBondContact O-N 2.88Å; L44-S47 PolarHBondContact O-N 3.43Å; L44-S47 PolarHBondContact O-OG 3.16Å; L44-C48 PolarHBondContact O-SG 2.76Å; L44-F80 HydrophobicContact CD2-CE1 4Å; L44-F80 HydrophobicContact CD2-CZ 3.76Å; L44-I138 HydrophobicContact CD1-CG2 4.11Å; L44-I138 HydrophobicContact CD2-CB 4.5Å; L44-I138 HydrophobicContact CD2-CG2 3.78Å; L44-F140 WeakPolarHBondContact CD1-O 3.16Å; L44-I141 HydrophobicContact CB-CD1 3.81Å; L44-I141 HydrophobicContact CD1-CD1 4.32Å; L44-P142 HydrophobicContact CD1-CG 4.5Å
45L94.2Very high93.6Very high5 Ų537.9 Ų37.93%0.02620%0.202CC..Hα-helixtrans-65-43178.5-73.6-179000112.1W15 I18 M35 L37 T41 R43 S47 C48 C49 F80W15-L45 HydrophobicContact CZ3-CD2 4.43Å; I18-L45 HydrophobicContact CD1-CD2 3.99Å; I18-L45 HydrophobicContact CG2-CD2 4.2Å; M35-L45 HydrophobicContact CE-CD1 3.46Å; M35-L45 VanDerWaalsContact CE-CD1 3.46Å; M35-L45 HydrophobicContact SD-CD1 3.75Å; L37-L45 HydrophobicContact CD1-CD1 3.68Å; L37-L45 HydrophobicContact CD2-CD1 3.65Å; L37-L45 HydrophobicContact CG-CD1 4.32Å; T41-L45 PolarHBondContact O-N 3.33Å; R43-L45 PolarHBondContact O-N 3.19Å; L45-S47 PolarHBondContact O-N 2.72Å; L45-S47 VanDerWaalsContact O-N 3.13Å; L45-C48 PolarHBondContact O-N 3.21Å; L45-C48 VanDerWaalsContact O-N 3.12Å; L45-C49 PolarHBondContact O-N 3.15Å; L45-C49 PolarHBondContact O-SG 3.1Å; L45-F80 HydrophobicContact CD1-CD1 4.13Å; L45-F80 HydrophobicContact CD2-CD1 4.4Å; L45-F80 HydrophobicContact CD2-CE1 4.12Å; L45-F80 HydrophobicContact CG-CD1 4.2Å; L45-F80 HydrophobicContact CG-CE1 4.13Å
46S91.8Very high93.3Very high90 Ų9044.7 Ų44.763%0.62923%0.234SC*.Hα-helixtrans-59.9-26177.271.60000113.2T42 R43T42-S46 WeakPolarHBondContact O-CB 3.3Å; T42-S46 PolarHBondContact O-N 3.03Å; T42-S46 PolarHBondContact O-OG 3.41Å; R43-S46 WeakPolarHBondContact CA-OG 3.3Å; R43-S46 PolarHBondContact O-N 3.15Å; R43-S46 PolarHBondContact O-OG 3.31Å
47S91.6Very high93Very high20 Ų2045.7 Ų45.714%0.1424%0.239CC..Hα-helixtrans-78.6-23.1179.9760000114K11 R43 L44 L45 P142K11-S47 WeakPolarHBondContact CD-O 3.34Å; K11-S47 WeakPolarHBondContact CE-O 3.45Å; K11-S47 PolarHBondContact NZ-O 3.38Å; R43-S47 PolarHBondContact O-N 2.81Å; L44-S47 PolarHBondContact O-N 3.43Å; L44-S47 PolarHBondContact O-OG 3.16Å; L45-S47 PolarHBondContact O-N 2.72Å; L45-S47 VanDerWaalsContact O-N 3.13Å; S47-P142 WeakPolarHBondContact OG-CD 3.21Å; S47-P142 WeakPolarHBondContact OG-CG 3.25Å
48C90.9Very high92.7Very high18 Ų1846.2 Ų46.212%0.12225%0.246CC..Hα-helixtrans-127.9-9-168.866.40000115.4K11 V14 W15 L44 L45 P142K11-C48 HydrophobicContact CB-CB 4.46Å; V14-C48 HydrophobicContact CG1-CB 4.47Å; W15-C48 HydrophobicContact CB-CB 4.15Å; L44-C48 PolarHBondContact O-SG 2.76Å; L45-C48 PolarHBondContact O-N 3.21Å; L45-C48 VanDerWaalsContact O-N 3.12Å; C48-P142 HydrophobicContact CB-CG 4.45Å
49C89.9Confident92.5Very high16 Ų1646.1 Ų46.111%0.10825%0.245CC..  trans-150.7162.5178.470.50000113W15 L45 D53W15-C49 HydrophobicContact CD2-CB 3.8Å; W15-C49 HydrophobicContact CE3-CB 3.46Å; W15-C49 VanDerWaalsContact CE3-CB 3.46Å; W15-C49 HydrophobicContact CH2-CB 3.88Å; W15-C49 HydrophobicContact CZ2-CB 4.19Å; W15-C49 HydrophobicContact CZ3-CB 3.49Å; W15-C49 VanDerWaalsContact CZ3-CB 3.49Å; W15-C49 VanDerWaalsContact CZ3-SG 3.59Å; L45-C49 PolarHBondContact O-N 3.15Å; L45-C49 PolarHBondContact O-SG 3.1Å; C49-D53 HydrophobicContact CB-CB 4.26Å
50K88.7Confident92.4Very high95 Ų9545 Ų4541%0.41324%0.241SC..  trans-104.1165.4175.4-69175.1179.8151.90111.4T52 D53 L54 D285K50-T52 WeakPolarHBondContact CB-OG1 3.34Å; K50-T52 PolarHBondContact O-N 2.95Å; K50-D53 PolarHBondContact N-OD2 3.41Å; K50-D53 WeakPolarHBondContact O-CB 3.29Å; K50-D53 PolarHBondContact O-N 3.28Å; K50-L54 PolarHBondContact O-N 3.11Å; K50-D285 WeakPolarHBondContact CE-OD2 3.44Å; K50-D285 IonicContact NZ-OD2 2.74Å; K50-D285 PolarHBondContact NZ-OD2 2.71Å
51M88.8Confident92.3Very high84 Ų8446.9 Ų46.941%0.41425%0.254SS..Hα-helixtrans-57.9-32.4171.9-170.464-167.400112.5D53 L54 L55 I62M51-D53 VanDerWaalsContact C-N 3.31Å; M51-D53 PolarHBondContact O-N 3.44Å; M51-L54 PolarHBondContact O-N 3.32Å; M51-L55 HydrophobicContact CE-CD2 4.12Å; M51-L55 HydrophobicContact CE-CG 4.13Å; M51-L55 HydrophobicContact CG-CD1 4.29Å; M51-L55 HydrophobicContact CG-CG 4.49Å; M51-L55 VanDerWaalsContact O-CG 3.28Å; M51-L55 WeakPolarHBondContact O-CG 3.44Å; M51-L55 PolarHBondContact O-N 3.27Å; M51-I62 HydrophobicContact SD-CD1 3.65Å; M51-I62 HydrophobicContact SD-CG1 4.33Å
52T90.1Very high92.2Very high77 Ų7749.9 Ų49.947%0.47227%0.27SS..Hα-helixtrans-60.2-42.8174.947.70000111.7K50 L54 L55 E56K50-T52 WeakPolarHBondContact CB-OG1 3.34Å; K50-T52 PolarHBondContact O-N 2.95Å; T52-L54 VanDerWaalsContact C-N 3.35Å; T52-L54 PolarHBondContact O-N 3.02Å; T52-L55 PolarHBondContact O-N 3.35Å; T52-E56 WeakPolarHBondContact O-CG 3.5Å; T52-E56 PolarHBondContact O-N 2.85Å; T52-E56 VanDerWaalsContact O-N 3.1Å
53D91.6Very high92.2Very high42 Ų4249.9 Ų49.923%0.22527%0.265CS..Hα-helixtrans-68.3-39.5-178.3-45.8-29.4000109.9W15 C49 K50 M51 E56 E57W15-D53 HydrophobicContact CH2-CB 4.22Å; W15-D53 HydrophobicContact CZ2-CB 3.75Å; C49-D53 HydrophobicContact CB-CB 4.26Å; K50-D53 PolarHBondContact N-OD2 3.41Å; K50-D53 WeakPolarHBondContact O-CB 3.29Å; K50-D53 PolarHBondContact O-N 3.28Å; M51-D53 VanDerWaalsContact C-N 3.31Å; M51-D53 PolarHBondContact O-N 3.44Å; D53-E56 WeakPolarHBondContact O-CB 3.41Å; D53-E56 PolarHBondContact O-N 3.43Å; D53-E57 WeakPolarHBondContact O-CG 3.47Å; D53-E57 PolarHBondContact O-N 3.44Å
54L92.2Very high92.3Very high5 Ų546.3 Ų46.33%0.02626%0.255CS..Hα-helixtrans-67.8-36.8176.9-64.1174.4000112.8W15 F23 M35 K50 M51 T52 E56 E57 G58 V59 I62W15-L54 HydrophobicContact CH2-CD2 4.02Å; W15-L54 HydrophobicContact CZ3-CD2 4.17Å; F23-L54 HydrophobicContact CE1-CD2 4.34Å; F23-L54 HydrophobicContact CE2-CD2 3.95Å; F23-L54 HydrophobicContact CZ-CD2 3.47Å; F23-L54 VanDerWaalsContact CZ-CD2 3.47Å; M35-L54 HydrophobicContact SD-CD2 4.35Å; K50-L54 PolarHBondContact O-N 3.11Å; M51-L54 PolarHBondContact O-N 3.32Å; T52-L54 VanDerWaalsContact C-N 3.35Å; T52-L54 PolarHBondContact O-N 3.02Å; L54-E56 VanDerWaalsContact C-N 3.33Å; L54-E57 PolarHBondContact O-N 3.15Å; L54-G58 PolarHBondContact O-N 3.15Å; L54-V59 HydrophobicContact CB-CB 4.28Å; L54-V59 WeakPolarHBondContact O-CB 3.17Å; L54-V59 PolarHBondContact O-N 3.3Å; L54-I62 HydrophobicContact CD1-CD1 3.34Å; L54-I62 HydrophobicContact CD1-CG1 4.37Å
55L92Very high92.4Very high76 Ų7646.3 Ų46.340%0.39826%0.255SS..Hα-helixtrans-62.9-40.3173.6-73.5166.3000111.4W32 M51 T52 E57 G58 V59W32-L55 WeakPolarHBondContact CZ3-O 3.26Å; M51-L55 HydrophobicContact CE-CD2 4.12Å; M51-L55 HydrophobicContact CE-CG 4.13Å; M51-L55 HydrophobicContact CG-CD1 4.29Å; M51-L55 HydrophobicContact CG-CG 4.49Å; M51-L55 VanDerWaalsContact O-CG 3.28Å; M51-L55 WeakPolarHBondContact O-CG 3.44Å; M51-L55 PolarHBondContact O-N 3.27Å; T52-L55 PolarHBondContact O-N 3.35Å; L55-E57 VanDerWaalsContact C-N 3.26Å; L55-E57 PolarHBondContact O-N 3.02Å; L55-G58 PolarHBondContact O-N 3.2Å; L55-G58 VanDerWaalsContact O-N 3.12Å; L55-V59 WeakPolarHBondContact CD2-O 3.46Å
56E91.1Very high92.5Very high144 Ų14448.7 Ų48.767%0.67326%0.264SS*.Hα-helixtrans-63.1-31.8175.7-71.7175.6-170.600112.5T52 D53 L54 G58T52-E56 WeakPolarHBondContact O-CG 3.5Å; T52-E56 PolarHBondContact O-N 2.85Å; T52-E56 VanDerWaalsContact O-N 3.1Å; D53-E56 WeakPolarHBondContact O-CB 3.41Å; D53-E56 PolarHBondContact O-N 3.43Å; L54-E56 VanDerWaalsContact C-N 3.33Å; E56-G58 VanDerWaalsContact C-N 3.26Å; E56-G58 PolarHBondContact O-N 2.98Å
57E91.4Very high92.7Very high21 Ų2151.4 Ų51.410%0.09826%0.264CS..THydrogen-bonded Turntrans-846.9175.8-59.6-53148.900114.1W15 K19 F23 D53 L54 L55W15-E57 HydrophobicContact CH2-CG 4.39Å; W15-E57 HydrophobicContact CZ2-CG 4.43Å; K19-E57 WeakPolarHBondContact CE-OE1 3.29Å; K19-E57 IonicContact NZ-OE1 3.97Å; K19-E57 PolarHBondContact NZ-OE1 3.19Å; F23-E57 HydrophobicContact CB-CB 4.02Å; F23-E57 HydrophobicContact CB-CG 4.11Å; F23-E57 HydrophobicContact CD1-CB 3.8Å; F23-E57 HydrophobicContact CD1-CG 4.46Å; F23-E57 HydrophobicContact CD2-CB 4.17Å; F23-E57 HydrophobicContact CD2-CG 3.94Å; F23-E57 HydrophobicContact CE1-CB 4.34Å; F23-E57 HydrophobicContact CG-CB 3.73Å; F23-E57 HydrophobicContact CG-CG 3.92Å; D53-E57 WeakPolarHBondContact O-CG 3.47Å; D53-E57 PolarHBondContact O-N 3.44Å; L54-E57 PolarHBondContact O-N 3.15Å; L55-E57 VanDerWaalsContact C-N 3.26Å; L55-E57 PolarHBondContact O-N 3.02Å
58G92.3Very high92.7Very high15 Ų1557.8 Ų57.816%0.15530%0.296CS..THydrogen-bonded Turntrans83.921175.400000114.9W32 K33 L54 L55 E56W32-G58 WeakPolarHBondContact CA-O 3.39Å; K33-G58 PolarHBondContact N-O 2.86Å; L54-G58 PolarHBondContact O-N 3.15Å; L55-G58 PolarHBondContact O-N 3.2Å; L55-G58 VanDerWaalsContact O-N 3.12Å; E56-G58 VanDerWaalsContact C-N 3.26Å; E56-G58 PolarHBondContact O-N 2.98Å
59V93.9Very high92.9Very high1 Ų157.4 Ų57.41%0.00629%0.292CS..EExtended strand (participates in β ladder)trans-95.1118.1172.2176.90000110F23 K33 M35 L54 L55 I62 L78F23-V59 HydrophobicContact CD1-CG2 4.39Å; F23-V59 HydrophobicContact CE1-CG2 3.7Å; K33-V59 WeakPolarHBondContact O-CA 3.46Å; M35-V59 HydrophobicContact CB-CG1 3.5Å; M35-V59 VanDerWaalsContact CB-CG1 3.5Å; M35-V59 HydrophobicContact CB-CG2 4.26Å; M35-V59 HydrophobicContact SD-CG1 4.43Å; M35-V59 HydrophobicContact SD-CG2 4.3Å; L54-V59 HydrophobicContact CB-CB 4.28Å; L54-V59 WeakPolarHBondContact O-CB 3.17Å; L54-V59 PolarHBondContact O-N 3.3Å; L55-V59 WeakPolarHBondContact CD2-O 3.46Å; V59-I62 HydrophobicContact CG1-CG1 4.15Å; V59-L78 HydrophobicContact CG2-CD2 4.44Å
60T91.7Very high93Very high46 Ų4664.3 Ų64.328%0.28232%0.323SS..EExtended strand (participates in β ladder)trans-89.8-35.2-179.9510000113.5W32 K33 M75W32-T60 HydrophobicContact CB-CG2 3.71Å; W32-T60 HydrophobicContact CD2-CG2 3.51Å; W32-T60 HydrophobicContact CE3-CG2 3.26Å; W32-T60 HydrophobicContact CG-CG2 3.73Å; W32-T60 HydrophobicContact CZ3-CG2 4.05Å; K33-T60 PolarHBondContact O-N 3.26Å; K33-T60 PolarHBondContact O-OG1 3.16Å; T60-M75 WeakPolarHBondContact OG1-CE 3.41Å
61V93.1Very high93.2Very high65 Ų6562.8 Ų62.839%0.39432%0.323SS..EExtended strand (participates in β ladder)trans-141.9138.9-171-178.50000108.5I34 M35 E63I34-V61 HydrophobicContact CG2-CB 4.28Å; M35-V61 PolarHBondContact N-O 2.92Å; V61-E63 HydrophobicContact CG1-CG 3.85Å
62I95Very high93.4Very high64 Ų6460.4 Ų60.433%0.32831%0.313SS..EExtended strand (participates in β ladder)trans-113.9126.8173.3-56.3170.3000107.7M35 L37 M51 L54 V59M35-I62 HydrophobicContact CB-CG1 4.47Å; M35-I62 CarbonylContact O-C 3.55Å; M35-I62 WeakPolarHBondContact O-CA 3.35Å; L37-I62 HydrophobicContact CD1-CG2 3.39Å; L37-I62 HydrophobicContact CG-CG2 3.92Å; M51-I62 HydrophobicContact SD-CD1 3.65Å; M51-I62 HydrophobicContact SD-CG1 4.33Å; L54-I62 HydrophobicContact CD1-CD1 3.34Å; L54-I62 HydrophobicContact CD1-CG1 4.37Å; V59-I62 HydrophobicContact CG1-CG1 4.15Å
63E96.5Very high93.5Very high56 Ų5663 Ų6326%0.26231%0.314SS..EExtended strand (participates in β ladder)trans-129152175.7-59.1-168.7111.400111.8M35 L36 L37 V61 R69M35-E63 PolarHBondContact O-N 3.47Å; L36-E63 WeakPolarHBondContact CA-O 3.41Å; L36-E63 HydrophobicContact CD1-CB 3.91Å; L37-E63 PolarHBondContact N-O 2.89Å; V61-E63 HydrophobicContact CG1-CG 3.85Å; E63-R69 HydrophobicContact CB-CG 4.21Å; E63-R69 WeakPolarHBondContact OE2-CD 3.31Å; E63-R69 WeakPolarHBondContact OE2-CG 3.45Å
64N97Very high93.5Very high33 Ų3367.7 Ų67.718%0.17634%0.335CS..EExtended strand (participates in β ladder)trans-81.4129.6174-175.6-52.6000110.1L37 D39 Y66 K67 R69L37-N64 CarbonylContact O-C 3.54Å; L37-N64 WeakPolarHBondContact O-CA 3.5Å; D39-N64 PolarHBondContact OD1-ND2 3.44Å; N64-Y66 PolarHBondContact O-N 2.96Å; N64-Y66 WeakPolarHBondContact OD1-CB 3.38Å; N64-Y66 WeakPolarHBondContact OD1-CD2 3.41Å; N64-Y66 PolarHBondContact OD1-N 2.82Å; N64-K67 HydrophobicContact CB-CD 4.17Å; N64-K67 HydrophobicContact CB-CG 4.11Å; N64-K67 PolarHBondContact O-N 2.91Å; N64-R69 PolarHBondContact O-NH1 3.28Å
65I97.4Very high93.6Very high0 Ų069.3 Ų69.30%034%0.343CS..THydrogen-bonded Turntrans-64.5-20.7-177.3-163.6174.6000113.6L37 D38 R69 Y79 I81 S87 C90 F91L37-I65 PolarHBondContact O-N 3.22Å; D38-I65 HydrophobicContact CB-CG2 3.92Å; I65-R69 PolarHBondContact O-NH1 3.26Å; I65-R69 PolarHBondContact O-NH2 3.01Å; I65-Y79 HydrophobicContact CD1-CD1 3.87Å; I65-Y79 HydrophobicContact CD1-CE1 4.06Å; I65-Y79 HydrophobicContact CG1-CE1 4.44Å; I65-I81 HydrophobicContact CD1-CD1 4.1Å; I65-I81 HydrophobicContact CD1-CG2 3.96Å; I65-S87 WeakPolarHBondContact CD1-O 3.33Å; I65-C90 HydrophobicContact CD1-CB 4.23Å; I65-C90 HydrophobicContact CG1-CB 3.83Å; I65-F91 HydrophobicContact CD1-CB 4.15Å
66Y96.6Very high93.7Very high55 Ų5566.5 Ų66.522%0.21633%0.327CS..THydrogen-bonded Turntrans-88.1-17.2178.8-52.2-46.3000114D38 D39 N64 K86 S87D38-Y66 HydrophobicContact CB-CE2 4.01Å; D39-Y66 WeakPolarHBondContact OD2-CE2 3.31Å; N64-Y66 PolarHBondContact O-N 2.96Å; N64-Y66 WeakPolarHBondContact OD1-CB 3.38Å; N64-Y66 WeakPolarHBondContact OD1-CD2 3.41Å; N64-Y66 PolarHBondContact OD1-N 2.82Å; Y66-K86 HydrophobicContact CD1-CD 4.13Å; Y66-K86 HydrophobicContact CD1-CG 4.07Å; Y66-K86 HydrophobicContact CE1-CB 4.3Å; Y66-K86 HydrophobicContact CE1-CD 3.7Å; Y66-K86 HydrophobicContact CE1-CG 3.61Å; Y66-K86 HydrophobicContact CE2-CD 4.49Å; Y66-S87 PolarHBondContact OH-OG 2.94Å
67K95.4Very high94Very high146 Ų14659.7 Ų59.764%0.63530%0.295SS*.SBendtrans-77.9159.1178.1-68.8-173.9178.2-178.60111.6N64 R69N64-K67 HydrophobicContact CB-CD 4.17Å; N64-K67 HydrophobicContact CB-CG 4.11Å; N64-K67 PolarHBondContact O-N 2.91Å; K67-R69 PolarHBondContact O-NH1 3.25Å
68N91.4Very high94.3Very high154 Ų15458.7 Ų58.782%0.82429%0.291SS*.  trans-76.7132.4165-166.321.7000109K102N68-K102 PolarHBondContact OD1-NZ 3.02Å
69R94.2Very high94.5Very high10 Ų1058 Ų584%0.03828%0.284CS..  trans-125.9148.9-172.5-61.8169.3-65.7-79.81.8110.4E63 N64 I65 K67 D94 K102 Y103E63-R69 HydrophobicContact CB-CG 4.21Å; E63-R69 WeakPolarHBondContact OE2-CD 3.31Å; E63-R69 WeakPolarHBondContact OE2-CG 3.45Å; N64-R69 PolarHBondContact O-NH1 3.28Å; I65-R69 PolarHBondContact O-NH1 3.26Å; I65-R69 PolarHBondContact O-NH2 3.01Å; K67-R69 PolarHBondContact O-NH1 3.25Å; R69-D94 IonicContact CZ-OD1 2.73Å; R69-D94 IonicContact CZ-OD2 3.59Å; R69-D94 IonicContact NE-OD2 3.35Å; R69-D94 VanDerWaalsContact NH2-CG 3.27Å; R69-D94 IonicContact NH2-OD1 3.47Å; R69-D94 PolarHBondContact NH2-OD1 3.17Å; R69-D94 IonicContact NH2-OD2 2.58Å; R69-D94 PolarHBondContact NH2-OD2 2.78Å; R69-K102 PolarHBondContact O-NZ 3Å; R69-Y103 WeakPolarHBondContact CD-OH 3.31Å; R69-Y103 PolarHBondContact NE-OH 3.18Å
70E91.9Very high94.7Very high161 Ų16158 Ų5875%0.75228%0.283SS*.  trans-73.7138.7175.4-65.7-170.9164.500111.4V72E70-V72 PolarHBondContact O-N 2.71Å
71P92.6Very high95Very high63 Ų6355.8 Ų55.841%0.40927%0.27SS..  trans-65.1120.1174.5-24.836.1000112.8R73 K102P71-R73 HydrophobicContact CB-CG 4.38Å; P71-K102 CarbonylContact C-O 3.42Å; P71-K102 HydrophobicContact CG-CG 4.43Å
72V93.4Very high95.1Very high34 Ų3453.3 Ų53.321%0.20626%0.256CS..BIsolated β-bridgetrans-114.273.4173.9-166.90000110.1I34 E70 Q74 M75 K102 Y103I34-V72 HydrophobicContact CD1-CB 3.57Å; I34-V72 HydrophobicContact CD1-CG1 3.85Å; I34-V72 HydrophobicContact CD1-CG2 3.73Å; E70-V72 PolarHBondContact O-N 2.71Å; V72-Q74 HydrophobicContact CG1-CG 4.44Å; V72-Q74 VanDerWaalsContact CG1-NE2 3.29Å; V72-Q74 PolarHBondContact O-N 3.19Å; V72-Q74 VanDerWaalsContact O-N 3.16Å; V72-M75 HydrophobicContact CG1-CB 4.03Å; V72-M75 HydrophobicContact CG1-CG 3.86Å; V72-M75 HydrophobicContact CG1-SD 4.01Å; V72-M75 PolarHBondContact O-N 3.11Å; V72-M75 VanDerWaalsContact O-N 3.15Å; V72-K102 CarbonylContact C-O 3.6Å; V72-K102 PolarHBondContact N-O 3.4Å; V72-Y103 HydrophobicContact CB-CD1 4.48Å
73R92Very high95.1Very high133 Ų13351.3 Ų51.350%0.50225%0.247SC..THydrogen-bonded Turntrans-67-18-167.2-62.8-172.4179.891.4-4.7115.1P71 K101 K102 K104P71-R73 HydrophobicContact CB-CG 4.38Å; R73-K101 WeakPolarHBondContact CG-O 3.41Å; R73-K101 PolarHBondContact NE-O 3.42Å; R73-K102 PolarHBondContact N-O 3.13Å; R73-K104 WeakPolarHBondContact O-CB 3.41Å; R73-K104 PolarHBondContact O-N 2.8Å
74Q92Very high95Very high139 Ų13951 Ų5165%0.6525%0.249SC*.THydrogen-bonded Turntrans-80.3-25.2177.969.5-78.715.600112.9V72V72-Q74 HydrophobicContact CG1-CG 4.44Å; V72-Q74 VanDerWaalsContact CG1-NE2 3.29Å; V72-Q74 PolarHBondContact O-N 3.19Å; V72-Q74 VanDerWaalsContact O-N 3.16Å
75M94.3Very high95Very high39 Ų3953.2 Ų53.219%0.19227%0.265CS..SBendtrans-98156.6-177.4-65.1-170.97200112W32 I34 T60 V72 K104W32-M75 VanDerWaalsContact C-CE 3.46Å; W32-M75 HydrophobicContact CB-CE 3.65Å; W32-M75 WeakPolarHBondContact O-CE 3.23Å; I34-M75 HydrophobicContact CD1-CB 4.15Å; I34-M75 HydrophobicContact CD1-SD 4.07Å; I34-M75 HydrophobicContact CG1-CB 4.29Å; I34-M75 HydrophobicContact CG1-CE 3.99Å; I34-M75 HydrophobicContact CG1-SD 3.94Å; T60-M75 WeakPolarHBondContact OG1-CE 3.41Å; V72-M75 HydrophobicContact CG1-CB 4.03Å; V72-M75 HydrophobicContact CG1-CG 3.86Å; V72-M75 HydrophobicContact CG1-SD 4.01Å; V72-M75 PolarHBondContact O-N 3.11Å; V72-M75 VanDerWaalsContact O-N 3.15Å; M75-K104 VanDerWaalsContact O-CB 3.26Å; M75-K104 WeakPolarHBondContact O-CB 3.17Å; M75-K104 PolarHBondContact O-N 3.12Å
76K95.1Very high94.9Very high18 Ų1859 Ų598%0.07829%0.29CS..EExtended strand (participates in β ladder)trans-92.5149.7169.3-59.9-178.6-171.5159.70109.8E31 I34 K104 A105 Y107E31-K76 WeakPolarHBondContact OE1-CE 3.47Å; E31-K76 IonicContact OE1-NZ 2.63Å; E31-K76 PolarHBondContact OE1-NZ 2.94Å; E31-K76 IonicContact OE2-NZ 2.97Å; E31-K76 PolarHBondContact OE2-NZ 3.28Å; I34-K76 PolarHBondContact N-O 2.98Å; I34-K76 VanDerWaalsContact N-O 3.12Å; K76-K104 HydrophobicContact CG-CB 4.29Å; K76-A105 WeakPolarHBondContact CA-O 3.33Å; K76-A105 HydrophobicContact CD-CB 4.35Å; K76-A105 HydrophobicContact CG-CB 4.15Å; K76-Y107 HydrophobicContact CB-CD2 4.47Å; K76-Y107 HydrophobicContact CB-CE2 4.03Å; K76-Y107 HydrophobicContact CD-CE2 3.52Å; K76-Y107 HydrophobicContact CG-CE2 4.44Å; K76-Y107 PolarHBondContact NZ-OH 2.9Å; K76-Y107 VanDerWaalsContact NZ-OH 3.07Å
77A96.8Very high94.9Very high0 Ų056.4 Ų56.40%028%0.28CS..EExtended strand (participates in β ladder)trans-105.3134178.500000111I34 L36 Y79 Y103 A105 A106 Y107I34-A77 CarbonylContact O-C 3.53Å; I34-A77 WeakPolarHBondContact O-CA 3.41Å; L36-A77 HydrophobicContact CD2-CB 3.59Å; A77-Y79 HydrophobicContact CB-CD2 4.12Å; A77-Y79 HydrophobicContact CB-CE2 3.46Å; A77-Y79 VanDerWaalsContact CB-CE2 3.46Å; A77-Y103 HydrophobicContact CB-CD1 4.09Å; A77-Y103 HydrophobicContact CB-CD2 3.45Å; A77-Y103 VanDerWaalsContact CB-CD2 3.45Å; A77-Y103 HydrophobicContact CB-CE2 3.94Å; A77-Y103 HydrophobicContact CB-CG 3.52Å; A77-A105 PolarHBondContact N-O 2.84Å; A77-A106 CarbonylContact O-C 3.55Å; A77-A106 WeakPolarHBondContact O-CA 3.37Å; A77-Y107 PolarHBondContact O-N 3.38Å
78L97.2Very high95Very high1 Ų149.4 Ų49.41%0.00525%0.25CC..EExtended strand (participates in β ladder)trans-102.8104.8171.9174.164.8000108.3V22 F23 I34 M35 L36 V59 Y109V22-L78 HydrophobicContact CG1-CD1 3.86Å; V22-L78 HydrophobicContact CG1-CD2 3.99Å; V22-L78 HydrophobicContact CG1-CG 4.38Å; F23-L78 HydrophobicContact CD1-CD2 4.05Å; F23-L78 HydrophobicContact CE1-CD2 3.63Å; I34-L78 PolarHBondContact O-N 3.17Å; M35-L78 CarbonylContact C-O 3.14Å; M35-L78 WeakPolarHBondContact CA-O 3.45Å; M35-L78 HydrophobicContact CE-CD2 4.06Å; M35-L78 HydrophobicContact CG-CD2 4.2Å; M35-L78 HydrophobicContact CG-CG 4.37Å; M35-L78 HydrophobicContact SD-CD2 4.4Å; L36-L78 PolarHBondContact N-O 3.45Å; V59-L78 HydrophobicContact CG2-CD2 4.44Å; L78-Y109 HydrophobicContact CD1-CD2 3.37Å; L78-Y109 HydrophobicContact CD1-CE2 3.35Å
79Y98Very high95.2Very high0 Ų045.3 Ų45.30%023%0.228CC..EExtended strand (participates in β ladder)trans-89.4113.5174.6-65-95.3000108.5L36 I65 A77 F91 D94 F95 Y103 A106 Y107 I108 Y109L36-Y79 HydrophobicContact CB-CD1 3.57Å; L36-Y79 HydrophobicContact CB-CE1 3.8Å; L36-Y79 HydrophobicContact CB-CG 4.16Å; L36-Y79 HydrophobicContact CG-CD1 4.03Å; L36-Y79 HydrophobicContact CG-CE1 3.73Å; I65-Y79 HydrophobicContact CD1-CD1 3.87Å; I65-Y79 HydrophobicContact CD1-CE1 4.06Å; I65-Y79 HydrophobicContact CG1-CE1 4.44Å; A77-Y79 HydrophobicContact CB-CD2 4.12Å; A77-Y79 HydrophobicContact CB-CE2 3.46Å; A77-Y79 VanDerWaalsContact CB-CE2 3.46Å; Y79-F91 AromaticContact CD1-CD2 3.82Å; Y79-F91 HydrophobicContact CD1-CD2 3.82Å; Y79-F91 AromaticContact CD2-CD2 3.92Å; Y79-F91 HydrophobicContact CD2-CD2 3.92Å; Y79-F91 AromaticContact CD2-CE2 3.97Å; Y79-F91 HydrophobicContact CD2-CE2 3.97Å; Y79-F91 HydrophobicContact CE1-CB 4.42Å; Y79-F91 AromaticContact CE1-CD2 3.66Å; Y79-F91 HydrophobicContact CE1-CD2 3.66Å; Y79-F91 HydrophobicContact CE1-CE2 4.5Å; Y79-F91 AromaticContact CE2-CD2 3.75Å; Y79-F91 HydrophobicContact CE2-CD2 3.75Å; Y79-F91 AromaticContact CE2-CE2 3.77Å; Y79-F91 HydrophobicContact CE2-CE2 3.77Å; Y79-F91 AromaticContact CG-CD2 3.94Å; Y79-F91 HydrophobicContact CG-CD2 3.94Å; Y79-F91 HydrophobicContact CG-CE2 4.41Å; Y79-F91 AromaticContact CZ-CD2 3.61Å; Y79-D94 WeakPolarHBondContact OH-CB 3.45Å; Y79-D94 PolarHBondContact OH-OD2 3.33Å; Y79-F95 AromaticContact CE2-CE2 3.91Å; Y79-F95 HydrophobicContact CE2-CE2 3.91Å; Y79-F95 HydrophobicContact CE2-CZ 4.37Å; Y79-F95 AromaticContact CZ-CE2 3.99Å; Y79-F95 WeakPolarHBondContact OH-CE2 3.31Å; Y79-Y103 VanDerWaalsContact OH-CD2 3.25Å; Y79-Y103 WeakPolarHBondContact OH-CD2 3.45Å; Y79-Y103 WeakPolarHBondContact OH-CE2 3.24Å; Y79-A106 HydrophobicContact CD2-CB 3.94Å; Y79-A106 HydrophobicContact CE2-CB 3.79Å; Y79-Y107 PolarHBondContact N-O 2.93Å; Y79-I108 CarbonylContact O-C 3.52Å; Y79-Y109 PolarHBondContact O-N 2.8Å
80F97.8Very high95.2Very high0 Ų045.4 Ų45.40%023%0.229CC..EExtended strand (participates in β ladder)trans-114.3102.7167179.2-136.1000106.4I18 M35 L36 L37 T41 L44 L45 Y109 T111 I136I18-F80 HydrophobicContact CD1-CE1 4.19Å; I18-F80 HydrophobicContact CD1-CZ 4.21Å; I18-F80 HydrophobicContact CG1-CZ 4.33Å; M35-F80 HydrophobicContact CE-CB 3.76Å; M35-F80 HydrophobicContact CE-CD1 3.99Å; M35-F80 HydrophobicContact CE-CG 4.26Å; L36-F80 PolarHBondContact O-N 3.28Å; L37-F80 HydrophobicContact CD2-CB 3.95Å; L37-F80 HydrophobicContact CD2-CD1 4.08Å; L37-F80 HydrophobicContact CD2-CG 4.49Å; T41-F80 WeakPolarHBondContact CB-O 3.4Å; T41-F80 HydrophobicContact CG2-CD1 3.96Å; T41-F80 HydrophobicContact CG2-CD2 4.38Å; T41-F80 HydrophobicContact CG2-CE1 4.03Å; T41-F80 HydrophobicContact CG2-CE2 4.41Å; T41-F80 HydrophobicContact CG2-CG 4.15Å; T41-F80 HydrophobicContact CG2-CZ 4.26Å; T41-F80 WeakPolarHBondContact CG2-O 3.31Å; T41-F80 PolarHBondContact OG1-O 3.48Å; L44-F80 HydrophobicContact CD2-CE1 4Å; L44-F80 HydrophobicContact CD2-CZ 3.76Å; L45-F80 HydrophobicContact CD1-CD1 4.13Å; L45-F80 HydrophobicContact CD2-CD1 4.4Å; L45-F80 HydrophobicContact CD2-CE1 4.12Å; L45-F80 HydrophobicContact CG-CD1 4.2Å; L45-F80 HydrophobicContact CG-CE1 4.13Å; F80-Y109 WeakPolarHBondContact CA-O 3.36Å; F80-T111 HydrophobicContact CD2-CG2 4.46Å; F80-T111 HydrophobicContact CE2-CG2 3.84Å; F80-T111 HydrophobicContact CZ-CG2 4.13Å; F80-I136 HydrophobicContact CD2-CD1 4.07Å; F80-I136 HydrophobicContact CE2-CD1 3.71Å
81I97.8Very high95.4Very high0 Ų037.8 Ų37.80%019%0.194CC..EExtended strand (participates in β ladder)trans-144.3157.9-166.457.1175.4000111.5D38 I65 Y109 F110 T111D38-I81 HydrophobicContact CB-CG2 4.38Å; I65-I81 HydrophobicContact CD1-CD1 4.1Å; I65-I81 HydrophobicContact CD1-CG2 3.96Å; I81-Y109 PolarHBondContact N-O 3.37Å; I81-F110 HydrophobicContact CD1-CE1 3.9Å; I81-F110 HydrophobicContact CG1-CD1 4Å; I81-F110 HydrophobicContact CG1-CE1 3.87Å; I81-F110 VanDerWaalsContact O-CA 3.27Å; I81-F110 WeakPolarHBondContact O-CA 3.37Å; I81-T111 PolarHBondContact O-N 2.87Å; I81-T111 VanDerWaalsContact O-N 3.09Å
82S95.7Very high95.5Very high14 Ų1435.5 Ų35.510%0.09818%0.178CC..  trans-75.9144169.5-38.50000110.3D38 F40 T84 S87 T111D38-S82 WeakPolarHBondContact OD2-CA 3.01Å; D38-S82 WeakPolarHBondContact OD2-CB 3.26Å; D38-S82 PolarHBondContact OD2-N 3.04Å; D38-S82 PolarHBondContact OD2-OG 2.61Å; F40-S82 WeakPolarHBondContact CD1-OG 3.37Å; S82-T84 PolarHBondContact O-N 2.85Å; S82-S87 WeakPolarHBondContact O-CB 3.24Å; S82-T111 WeakPolarHBondContact CA-OG1 3.45Å
83P94.7Very high95.5Very high21 Ų2141 Ų4114%0.13620%0.195CC..  trans-76.855.5-178.132.5-35.7000112.4F110 D112 F113 C114 L118P83-F110 HydrophobicContact CB-CB 4.39Å; P83-F110 HydrophobicContact CB-CD1 3.73Å; P83-F110 HydrophobicContact CB-CE1 4.22Å; P83-F110 HydrophobicContact CB-CG 4.12Å; P83-D112 HydrophobicContact CG-CB 4.11Å; P83-F113 VanDerWaalsContact CG-O 3.28Å; P83-F113 WeakPolarHBondContact CG-O 3.3Å; P83-C114 HydrophobicContact CB-CB 4.02Å; P83-L118 WeakPolarHBondContact O-CD1 3.47Å
84T94.3Very high95.6Very high51 Ų5134.7 Ų34.731%0.31317%0.172SC..  trans-95.3152.3177.971.20000111.4S82 K86 S87 V88S82-T84 PolarHBondContact O-N 2.85Å; T84-K86 PolarHBondContact O-N 3.3Å; T84-S87 PolarHBondContact O-N 3.09Å; T84-S87 WeakPolarHBondContact OG1-CB 3.43Å; T84-S87 PolarHBondContact OG1-N 3.11Å; T84-S87 VanDerWaalsContact OG1-N 3.11Å; T84-S87 PolarHBondContact OG1-OG 3.18Å; T84-V88 WeakPolarHBondContact O-CG2 3.39Å; T84-V88 PolarHBondContact O-N 2.9Å
85P96Very high95.7Very high79 Ų7928.5 Ų28.551%0.51314%0.143SC..Hα-helixtrans-53.1-41.6173.8-26.534.1000112.6V88 D89 L118P85-V88 PolarHBondContact O-N 2.94Å; P85-D89 VanDerWaalsContact O-CB 3.28Å; P85-D89 WeakPolarHBondContact O-CB 3.13Å; P85-D89 PolarHBondContact O-N 2.89Å; P85-L118 HydrophobicContact CB-CD2 4.34Å; P85-L118 HydrophobicContact CG-CD1 4.45Å; P85-L118 HydrophobicContact CG-CD2 4.3Å
86K96.6Very high95Very high121 Ų12129.9 Ų29.953%0.52617%0.166SC..Hα-helixtrans-62.5-46.3179.2-169.9-171.9175.6-173.10112.3Y66 T84 C90Y66-K86 HydrophobicContact CD1-CD 4.13Å; Y66-K86 HydrophobicContact CD1-CG 4.07Å; Y66-K86 HydrophobicContact CE1-CB 4.3Å; Y66-K86 HydrophobicContact CE1-CD 3.7Å; Y66-K86 HydrophobicContact CE1-CG 3.61Å; Y66-K86 HydrophobicContact CE2-CD 4.49Å; T84-K86 PolarHBondContact O-N 3.3Å; K86-C90 PolarHBondContact O-N 2.85Å; K86-C90 VanDerWaalsContact O-N 3.15Å; K86-C90 PolarHBondContact O-SG 3.49Å
87S96.5Very high94.3Very high0 Ų030.6 Ų30.60%017%0.174CC..Hα-helixtrans-66.4-43.9178.7-62.60000111.2D38 I65 Y66 S82 T84 C90 F91D38-S87 PolarHBondContact OD2-OG 2.86Å; I65-S87 WeakPolarHBondContact CD1-O 3.33Å; Y66-S87 PolarHBondContact OH-OG 2.94Å; S82-S87 WeakPolarHBondContact O-CB 3.24Å; T84-S87 PolarHBondContact O-N 3.09Å; T84-S87 WeakPolarHBondContact OG1-CB 3.43Å; T84-S87 PolarHBondContact OG1-N 3.11Å; T84-S87 VanDerWaalsContact OG1-N 3.11Å; T84-S87 PolarHBondContact OG1-OG 3.18Å; S87-C90 PolarHBondContact O-N 3.47Å; S87-F91 WeakPolarHBondContact O-CB 3.08Å; S87-F91 PolarHBondContact O-N 2.91Å
88V96.1Very high93.1Very high0 Ų039.5 Ų39.50%021%0.213CC..Hα-helixtrans-64.9-42.4178.4172.70000111.5T84 P85 C90 F91 L92 F110 L118 I122T84-V88 WeakPolarHBondContact O-CG2 3.39Å; T84-V88 PolarHBondContact O-N 2.9Å; P85-V88 PolarHBondContact O-N 2.94Å; V88-C90 VanDerWaalsContact C-N 3.34Å; V88-C90 PolarHBondContact O-N 2.92Å; V88-F91 WeakPolarHBondContact O-CB 3.47Å; V88-F91 PolarHBondContact O-N 3.44Å; V88-L92 HydrophobicContact CG1-CD1 4.03Å; V88-L92 HydrophobicContact CG1-CG 4.28Å; V88-L92 WeakPolarHBondContact O-CB 3.47Å; V88-L92 VanDerWaalsContact O-CG 3.26Å; V88-L92 WeakPolarHBondContact O-CG 3.46Å; V88-L92 PolarHBondContact O-N 2.75Å; V88-F110 HydrophobicContact CG2-CE1 4.21Å; V88-F110 HydrophobicContact CG2-CZ 4.33Å; V88-L118 HydrophobicContact CB-CD2 4.5Å; V88-L118 HydrophobicContact CG2-CB 4.31Å; V88-L118 HydrophobicContact CG2-CD1 4.19Å; V88-I122 HydrophobicContact CG1-CD1 3.97Å; V88-I122 HydrophobicContact CG1-CG1 3.76Å; V88-I122 HydrophobicContact CG2-CD1 4.23Å
89D95.5Very high92.3Very high68 Ų6844 Ų4436%0.36424%0.244SC..Hα-helixtrans-64.4-39.4177.9-73.4-11.3000112.4P85 L92 R93 K121P85-D89 VanDerWaalsContact O-CB 3.28Å; P85-D89 WeakPolarHBondContact O-CB 3.13Å; P85-D89 PolarHBondContact O-N 2.89Å; D89-L92 PolarHBondContact O-N 2.76Å; D89-R93 PolarHBondContact O-N 3.35Å; D89-R93 VanDerWaalsContact O-N 3.07Å; D89-K121 WeakPolarHBondContact OD1-CE 3.47Å; D89-K121 IonicContact OD1-NZ 2.6Å; D89-K121 PolarHBondContact OD1-NZ 2.69Å; D89-K121 IonicContact OD2-NZ 3.67Å
90C95.8Very high91.6Very high11 Ų1150.5 Ų50.57%0.07427%0.274CS..Hα-helixtrans-66.3-40.2174.4-67.90000111.9I65 K86 S87 V88 R93 D94I65-C90 HydrophobicContact CD1-CB 4.23Å; I65-C90 HydrophobicContact CG1-CB 3.83Å; K86-C90 PolarHBondContact O-N 2.85Å; K86-C90 VanDerWaalsContact O-N 3.15Å; K86-C90 PolarHBondContact O-SG 3.49Å; S87-C90 PolarHBondContact O-N 3.47Å; V88-C90 VanDerWaalsContact C-N 3.34Å; V88-C90 PolarHBondContact O-N 2.92Å; C90-R93 PolarHBondContact O-N 3.15Å; C90-R93 PolarHBondContact SG-NH2 2.82Å; C90-D94 PolarHBondContact O-N 2.81Å
91F95.6Very high91.2Very high1 Ų153.1 Ų53.10%0.00429%0.286CS..Hα-helixtrans-60.5-47.9173.3163.6-103.3000111.7I65 Y79 S87 V88 R93 D94 F95 A106 I108 I122 C126 I130I65-F91 HydrophobicContact CD1-CB 4.15Å; Y79-F91 AromaticContact CD1-CD2 3.82Å; Y79-F91 HydrophobicContact CD1-CD2 3.82Å; Y79-F91 AromaticContact CD2-CD2 3.92Å; Y79-F91 HydrophobicContact CD2-CD2 3.92Å; Y79-F91 AromaticContact CD2-CE2 3.97Å; Y79-F91 HydrophobicContact CD2-CE2 3.97Å; Y79-F91 HydrophobicContact CE1-CB 4.42Å; Y79-F91 AromaticContact CE1-CD2 3.66Å; Y79-F91 HydrophobicContact CE1-CD2 3.66Å; Y79-F91 HydrophobicContact CE1-CE2 4.5Å; Y79-F91 AromaticContact CE2-CD2 3.75Å; Y79-F91 HydrophobicContact CE2-CD2 3.75Å; Y79-F91 AromaticContact CE2-CE2 3.77Å; Y79-F91 HydrophobicContact CE2-CE2 3.77Å; Y79-F91 AromaticContact CG-CD2 3.94Å; Y79-F91 HydrophobicContact CG-CD2 3.94Å; Y79-F91 HydrophobicContact CG-CE2 4.41Å; Y79-F91 AromaticContact CZ-CD2 3.61Å; S87-F91 WeakPolarHBondContact O-CB 3.08Å; S87-F91 PolarHBondContact O-N 2.91Å; V88-F91 WeakPolarHBondContact O-CB 3.47Å; V88-F91 PolarHBondContact O-N 3.44Å; F91-R93 VanDerWaalsContact C-N 3.27Å; F91-R93 PolarHBondContact O-N 3.11Å; F91-D94 WeakPolarHBondContact O-CB 3.49Å; F91-D94 PolarHBondContact O-N 3.13Å; F91-D94 VanDerWaalsContact O-N 3.09Å; F91-F95 HydrophobicContact CD2-CD2 4.33Å; F91-F95 HydrophobicContact CD2-CE2 4.19Å; F91-F95 AromaticContact CE2-CD2 3.76Å; F91-F95 HydrophobicContact CE2-CD2 3.76Å; F91-F95 AromaticContact CE2-CE2 3.56Å; F91-F95 HydrophobicContact CE2-CE2 3.56Å; F91-F95 HydrophobicContact CZ-CD2 4.08Å; F91-F95 HydrophobicContact CZ-CE2 4.24Å; F91-A106 HydrophobicContact CE2-CB 3.72Å; F91-A106 HydrophobicContact CZ-CB 4.22Å; F91-I108 HydrophobicContact CD1-CD1 4.27Å; F91-I108 HydrophobicContact CD2-CD1 4.35Å; F91-I108 HydrophobicContact CE1-CD1 3.55Å; F91-I108 HydrophobicContact CE2-CD1 3.67Å; F91-I108 HydrophobicContact CE2-CG1 3.99Å; F91-I108 HydrophobicContact CZ-CD1 3.24Å; F91-I108 HydrophobicContact CZ-CG1 4.07Å; F91-I122 HydrophobicContact CD1-CG1 4.35Å; F91-I122 HydrophobicContact CE1-CG1 4.31Å; F91-I122 HydrophobicContact CE1-CG2 4.06Å; F91-C126 WeakPolarHBondContact CE1-SG 3.37Å; F91-I130 HydrophobicContact CE1-CD1 4.25Å; F91-I130 HydrophobicContact CZ-CD1 4.03Å; F91-I130 HydrophobicContact CZ-CG1 4.06Å
92L94.3Very high91Very high16 Ų1654.3 Ų54.38%0.08429%0.291CS..Hα-helixtrans-59.7-39179.7-72.7176.3000112.1V88 D89 D94 F95 G96 K121 I122V88-L92 HydrophobicContact CG1-CD1 4.03Å; V88-L92 HydrophobicContact CG1-CG 4.28Å; V88-L92 WeakPolarHBondContact O-CB 3.47Å; V88-L92 VanDerWaalsContact O-CG 3.26Å; V88-L92 WeakPolarHBondContact O-CG 3.46Å; V88-L92 PolarHBondContact O-N 2.75Å; D89-L92 PolarHBondContact O-N 2.76Å; L92-D94 VanDerWaalsContact C-N 3.27Å; L92-D94 PolarHBondContact O-N 2.89Å; L92-F95 CarbonylContact O-C 3.59Å; L92-F95 PolarHBondContact O-N 3.25Å; L92-F95 VanDerWaalsContact O-N 3.1Å; L92-G96 PolarHBondContact O-N 2.99Å; L92-G96 VanDerWaalsContact O-N 3.07Å; L92-K121 HydrophobicContact CD1-CB 4.47Å; L92-K121 HydrophobicContact CD1-CD 3.67Å; L92-K121 HydrophobicContact CD1-CG 3.64Å; L92-I122 HydrophobicContact CD2-CG1 4.4Å
93R92.9Very high91Very high150 Ų15053.7 Ų53.757%0.56629%0.287SS*.Hα-helixtrans-62.1-31.8176.9-173.9173.160.7-139-3.3112.9D89 C90 F91 F95 G96D89-R93 PolarHBondContact O-N 3.35Å; D89-R93 VanDerWaalsContact O-N 3.07Å; C90-R93 PolarHBondContact O-N 3.15Å; C90-R93 PolarHBondContact SG-NH2 2.82Å; F91-R93 VanDerWaalsContact C-N 3.27Å; F91-R93 PolarHBondContact O-N 3.11Å; R93-F95 PolarHBondContact O-N 3.48Å; R93-G96 PolarHBondContact O-N 3.05Å
94D95Very high91Very high0 Ų058.8 Ų58.80%031%0.307CS..THydrogen-bonded Turntrans-66.4-17177.1-70.3-17.5000113.1R69 Y79 C90 F91 L92 K101 K102 Y103R69-D94 IonicContact CZ-OD1 2.73Å; R69-D94 IonicContact CZ-OD2 3.59Å; R69-D94 IonicContact NE-OD2 3.35Å; R69-D94 VanDerWaalsContact NH2-CG 3.27Å; R69-D94 IonicContact NH2-OD1 3.47Å; R69-D94 PolarHBondContact NH2-OD1 3.17Å; R69-D94 IonicContact NH2-OD2 2.58Å; R69-D94 PolarHBondContact NH2-OD2 2.78Å; Y79-D94 WeakPolarHBondContact OH-CB 3.45Å; Y79-D94 PolarHBondContact OH-OD2 3.33Å; C90-D94 PolarHBondContact O-N 2.81Å; F91-D94 WeakPolarHBondContact O-CB 3.49Å; F91-D94 PolarHBondContact O-N 3.13Å; F91-D94 VanDerWaalsContact O-N 3.09Å; L92-D94 VanDerWaalsContact C-N 3.27Å; L92-D94 PolarHBondContact O-N 2.89Å; D94-K101 WeakPolarHBondContact O-CA 3.46Å; D94-K102 HydrophobicContact CB-CB 4.34Å; D94-K102 HydrophobicContact CB-CG 4.37Å; D94-K102 PolarHBondContact O-N 3.25Å; D94-K102 WeakPolarHBondContact OD1-CD 3.4Å; D94-Y103 HydrophobicContact CB-CE2 4.37Å
95F93.2Very high91Very high9 Ų956.4 Ų56.44%0.03929%0.292CS..THydrogen-bonded Turntrans-126.517.5-179.4-62.5-82.3000113.6Y79 F91 L92 R93 S97 K101 Y103 A106 C126Y79-F95 AromaticContact CE2-CE2 3.91Å; Y79-F95 HydrophobicContact CE2-CE2 3.91Å; Y79-F95 HydrophobicContact CE2-CZ 4.37Å; Y79-F95 AromaticContact CZ-CE2 3.99Å; Y79-F95 WeakPolarHBondContact OH-CE2 3.31Å; F91-F95 HydrophobicContact CD2-CD2 4.33Å; F91-F95 HydrophobicContact CD2-CE2 4.19Å; F91-F95 AromaticContact CE2-CD2 3.76Å; F91-F95 HydrophobicContact CE2-CD2 3.76Å; F91-F95 AromaticContact CE2-CE2 3.56Å; F91-F95 HydrophobicContact CE2-CE2 3.56Å; F91-F95 HydrophobicContact CZ-CD2 4.08Å; F91-F95 HydrophobicContact CZ-CE2 4.24Å; L92-F95 CarbonylContact O-C 3.59Å; L92-F95 PolarHBondContact O-N 3.25Å; L92-F95 VanDerWaalsContact O-N 3.1Å; R93-F95 PolarHBondContact O-N 3.48Å; F95-S97 VanDerWaalsContact C-N 3.33Å; F95-S97 PolarHBondContact O-N 2.82Å; F95-K101 HydrophobicContact CD1-CB 4.41Å; F95-K101 HydrophobicContact CD1-CD 4.14Å; F95-K101 HydrophobicContact CD1-CG 4.23Å; F95-Y103 HydrophobicContact CZ-CD2 4.19Å; F95-A106 HydrophobicContact CE2-CB 3.84Å; F95-A106 HydrophobicContact CZ-CB 3.75Å; F95-C126 HydrophobicContact CB-CB 3.79Å
96G81.1Confident91Very high67 Ų6752.6 Ų52.669%0.69127%0.267SS*.SBendtrans-60.8-33.1-170.300000115.1L92 R93L92-G96 PolarHBondContact O-N 2.99Å; L92-G96 VanDerWaalsContact O-N 3.07Å; R93-G96 PolarHBondContact O-N 3.05Å
97S79Confident91Very high34 Ų3447.2 Ų47.224%0.23824%0.243CC..SBendtrans-131.5152.3174.781.20000111.5F95 S99 E100 K101F95-S97 VanDerWaalsContact C-N 3.33Å; F95-S97 PolarHBondContact O-N 2.82Å; S97-S99 VanDerWaalsContact C-N 3.3Å; S97-S99 PolarHBondContact O-N 3.22Å; S97-E100 PolarHBondContact O-N 3.03Å; S97-E100 WeakPolarHBondContact OG-CB 3.31Å; S97-E100 VanDerWaalsContact OG-CD 3.32Å; S97-E100 WeakPolarHBondContact OG-CG 3.35Å; S97-E100 PolarHBondContact OG-N 3.37Å; S97-E100 VanDerWaalsContact OG-N 3.13Å; S97-E100 PolarHBondContact OG-OE2 3.39Å; S97-K101 VanDerWaalsContact O-CG 3.3Å; S97-K101 WeakPolarHBondContact O-CG 3.42Å; S97-K101 PolarHBondContact O-N 3.14Å
98K72.9Confident91Very high187 Ų18747.2 Ų47.281%0.81324%0.243SC*.SBendtrans-64.1-34.8-179.4-76.2-174.8-175.8172.70112.6
99S78.6Confident91.1Very high95 Ų9547.2 Ų47.266%0.66424%0.243SC*.SBendtrans-80.6-24.4-179.743.10000113.2S97S97-S99 VanDerWaalsContact C-N 3.3Å; S97-S99 PolarHBondContact O-N 3.22Å
100E83.4Confident91.2Very high136 Ų13644 Ų4464%0.63623%0.227SC*.SBendtrans-112.118.2-173.8-52.9164.1147.400113.6S97 K102S97-E100 PolarHBondContact O-N 3.03Å; S97-E100 WeakPolarHBondContact OG-CB 3.31Å; S97-E100 VanDerWaalsContact OG-CD 3.32Å; S97-E100 WeakPolarHBondContact OG-CG 3.35Å; S97-E100 PolarHBondContact OG-N 3.37Å; S97-E100 VanDerWaalsContact OG-N 3.13Å; S97-E100 PolarHBondContact OG-OE2 3.39Å; E100-K102 PolarHBondContact O-N 3Å
101K91Very high91.2Very high55 Ų5543.7 Ų43.724%0.23922%0.224CC..  trans-53.5134.3173.5-61.6-173.3-177.7-169.10110.3R73 D94 F95 S97 S129R73-K101 WeakPolarHBondContact CG-O 3.41Å; R73-K101 PolarHBondContact NE-O 3.42Å; D94-K101 WeakPolarHBondContact O-CA 3.46Å; F95-K101 HydrophobicContact CD1-CB 4.41Å; F95-K101 HydrophobicContact CD1-CD 4.14Å; F95-K101 HydrophobicContact CD1-CG 4.23Å; S97-K101 VanDerWaalsContact O-CG 3.3Å; S97-K101 WeakPolarHBondContact O-CG 3.42Å; S97-K101 PolarHBondContact O-N 3.14Å; K101-S129 PolarHBondContact NZ-OG 2.86Å
102K93.8Very high90.9Very high26 Ų2644.6 Ų44.611%0.11323%0.229CC..SBendtrans-74.8-32.1173.3-65.3-154.8-177.4-158.60112.6N68 R69 P71 V72 R73 D94 E100N68-K102 PolarHBondContact OD1-NZ 3.02Å; R69-K102 PolarHBondContact O-NZ 3Å; P71-K102 CarbonylContact C-O 3.42Å; P71-K102 HydrophobicContact CG-CG 4.43Å; V72-K102 CarbonylContact C-O 3.6Å; V72-K102 PolarHBondContact N-O 3.4Å; R73-K102 PolarHBondContact N-O 3.13Å; D94-K102 HydrophobicContact CB-CB 4.34Å; D94-K102 HydrophobicContact CB-CG 4.37Å; D94-K102 PolarHBondContact O-N 3.25Å; D94-K102 WeakPolarHBondContact OD1-CD 3.4Å; E100-K102 PolarHBondContact O-N 3Å
103Y95.3Very high90.6Very high1 Ų149.2 Ų49.20%0.00425%0.249CC..BIsolated β-bridgetrans-134.5160.8-173.3-47.5-67.4000112.4I34 L36 R69 V72 A77 Y79 D94 F95I34-Y103 HydrophobicContact CD1-CD1 4.28Å; I34-Y103 HydrophobicContact CD1-CE1 3.98Å; L36-Y103 HydrophobicContact CD2-CE2 4.43Å; R69-Y103 WeakPolarHBondContact CD-OH 3.31Å; R69-Y103 PolarHBondContact NE-OH 3.18Å; V72-Y103 HydrophobicContact CB-CD1 4.48Å; A77-Y103 HydrophobicContact CB-CD1 4.09Å; A77-Y103 HydrophobicContact CB-CD2 3.45Å; A77-Y103 VanDerWaalsContact CB-CD2 3.45Å; A77-Y103 HydrophobicContact CB-CE2 3.94Å; A77-Y103 HydrophobicContact CB-CG 3.52Å; Y79-Y103 VanDerWaalsContact OH-CD2 3.25Å; Y79-Y103 WeakPolarHBondContact OH-CD2 3.45Å; Y79-Y103 WeakPolarHBondContact OH-CE2 3.24Å; D94-Y103 HydrophobicContact CB-CE2 4.37Å; F95-Y103 HydrophobicContact CZ-CD2 4.19Å
104K93.9Very high90.6Very high128 Ų12842.2 Ų42.256%0.55722%0.223SC*.SBendtrans-63.2-43.4179.7-172.4173.4-179.5174.70112.7R73 M75 K76R73-K104 WeakPolarHBondContact O-CB 3.41Å; R73-K104 PolarHBondContact O-N 2.8Å; M75-K104 VanDerWaalsContact O-CB 3.26Å; M75-K104 WeakPolarHBondContact O-CB 3.17Å; M75-K104 PolarHBondContact O-N 3.12Å; K76-K104 HydrophobicContact CG-CB 4.29Å
105A94.4Very high90.5Very high0 Ų044.6 Ų44.60%024%0.238CC..  trans-163164.4-17900000110.2K76 A77 S129 R131K76-A105 WeakPolarHBondContact CA-O 3.33Å; K76-A105 HydrophobicContact CD-CB 4.35Å; K76-A105 HydrophobicContact CG-CB 4.15Å; A77-A105 PolarHBondContact N-O 2.84Å; A105-S129 CarbonylContact C-O 3.52Å; A105-S129 VanDerWaalsContact CA-O 3.26Å; A105-S129 WeakPolarHBondContact CA-O 3.5Å; A105-S129 WeakPolarHBondContact CB-O 3.39Å; A105-R131 HydrophobicContact CB-CG 3.82Å
106A96.1Very high90.5Very high0 Ų049.4 Ų49.40%026%0.264CS..EExtended strand (participates in β ladder)trans-117.2138.3-18000000112.4A77 Y79 F91 F95 I108 S129 I130 R131A77-A106 CarbonylContact O-C 3.55Å; A77-A106 WeakPolarHBondContact O-CA 3.37Å; Y79-A106 HydrophobicContact CD2-CB 3.94Å; Y79-A106 HydrophobicContact CE2-CB 3.79Å; F91-A106 HydrophobicContact CE2-CB 3.72Å; F91-A106 HydrophobicContact CZ-CB 4.22Å; F95-A106 HydrophobicContact CE2-CB 3.84Å; F95-A106 HydrophobicContact CZ-CB 3.75Å; A106-I108 HydrophobicContact CB-CG1 4.3Å; A106-S129 PolarHBondContact N-O 3.16Å; A106-I130 CarbonylContact O-C 3.57Å; A106-I130 WeakPolarHBondContact O-CA 3.4Å; A106-R131 PolarHBondContact O-N 2.8Å
107Y97Very high91.2Very high7 Ų750.4 Ų50.43%0.02726%0.261CS..EExtended strand (participates in β ladder)trans-106.6127.7157.5-60-92.9000107C26 K33 K76 A77 Y79 R131 R132C26-Y107 HydrophobicContact CB-CD1 3.67Å; C26-Y107 HydrophobicContact CB-CE1 3.92Å; C26-Y107 HydrophobicContact CB-CG 4.05Å; K33-Y107 HydrophobicContact CD-CD2 4.45Å; K33-Y107 HydrophobicContact CD-CE2 4.34Å; K76-Y107 HydrophobicContact CB-CD2 4.47Å; K76-Y107 HydrophobicContact CB-CE2 4.03Å; K76-Y107 HydrophobicContact CD-CE2 3.52Å; K76-Y107 HydrophobicContact CG-CE2 4.44Å; K76-Y107 PolarHBondContact NZ-OH 2.9Å; K76-Y107 VanDerWaalsContact NZ-OH 3.07Å; A77-Y107 PolarHBondContact O-N 3.38Å; Y79-Y107 PolarHBondContact N-O 2.93Å; Y107-R131 HydrophobicContact CD1-CB 4Å; Y107-R131 HydrophobicContact CE1-CB 3.69Å; Y107-R132 HydrophobicContact CD1-CB 3.84Å; Y107-R132 HydrophobicContact CD1-CG 3.62Å; Y107-R132 HydrophobicContact CE1-CG 3.99Å
108I96.9Very high91.9Very high0 Ų049.6 Ų49.60%025%0.254CS..EExtended strand (participates in β ladder)trans-118.9128.6-176.7-49.2172.8000108.8Y79 F91 A106 F110 I122 I130 R132 C133 K134Y79-I108 CarbonylContact O-C 3.52Å; F91-I108 HydrophobicContact CD1-CD1 4.27Å; F91-I108 HydrophobicContact CD2-CD1 4.35Å; F91-I108 HydrophobicContact CE1-CD1 3.55Å; F91-I108 HydrophobicContact CE2-CD1 3.67Å; F91-I108 HydrophobicContact CE2-CG1 3.99Å; F91-I108 HydrophobicContact CZ-CD1 3.24Å; F91-I108 HydrophobicContact CZ-CG1 4.07Å; A106-I108 HydrophobicContact CB-CG1 4.3Å; I108-F110 HydrophobicContact CG2-CD2 4.24Å; I108-F110 HydrophobicContact CG2-CE1 4.08Å; I108-F110 HydrophobicContact CG2-CE2 3.75Å; I108-F110 HydrophobicContact CG2-CZ 3.66Å; I108-I122 HydrophobicContact CD1-CG2 4.44Å; I108-I130 HydrophobicContact CD1-CD1 3.68Å; I108-I130 HydrophobicContact CD1-CG1 3.95Å; I108-I130 HydrophobicContact CD1-CG2 4.14Å; I108-I130 HydrophobicContact CG1-CG2 4.45Å; I108-R132 PolarHBondContact N-O 2.85Å; I108-C133 CarbonylContact O-C 3.44Å; I108-C133 VanDerWaalsContact O-CA 3.22Å; I108-C133 WeakPolarHBondContact O-CA 3.41Å; I108-K134 PolarHBondContact O-N 3.39Å
109Y97.8Very high93Very high0 Ų044.7 Ų44.70%023%0.232CC..EExtended strand (participates in β ladder)trans-130.7112.4177.8-69.2-81.5000108.5T21 V22 D25 C26 L78 Y79 F80 I81 K134 I136T21-Y109 VanDerWaalsContact O-CE1 3.28Å; T21-Y109 WeakPolarHBondContact O-CE1 3.36Å; V22-Y109 HydrophobicContact CG1-CD2 3.77Å; V22-Y109 HydrophobicContact CG1-CE2 3.98Å; V22-Y109 HydrophobicContact CG1-CG 4.04Å; V22-Y109 HydrophobicContact CG2-CD1 4.16Å; V22-Y109 HydrophobicContact CG2-CG 4.15Å; D25-Y109 HydrophobicContact CB-CE1 4.48Å; D25-Y109 PolarHBondContact OD2-OH 3.25Å; C26-Y109 HydrophobicContact CB-CE2 4.33Å; C26-Y109 WeakPolarHBondContact CB-OH 3.5Å; L78-Y109 HydrophobicContact CD1-CD2 3.37Å; L78-Y109 HydrophobicContact CD1-CE2 3.35Å; Y79-Y109 PolarHBondContact O-N 2.8Å; F80-Y109 WeakPolarHBondContact CA-O 3.36Å; I81-Y109 PolarHBondContact N-O 3.37Å; Y109-K134 CarbonylContact C-O 3.59Å; Y109-K134 VanDerWaalsContact CA-O 3.28Å; Y109-K134 WeakPolarHBondContact CA-O 3.4Å; Y109-K134 HydrophobicContact CD1-CB 4.01Å; Y109-K134 HydrophobicContact CE1-CB 4.08Å; Y109-I136 HydrophobicContact CD1-CD1 4.01Å; Y109-I136 HydrophobicContact CD1-CG1 4.36Å; Y109-I136 HydrophobicContact CG-CD1 4.2Å
110F97.5Very high93.7Very high2 Ų244.4 Ų44.41%0.00922%0.223CC..EExtended strand (participates in β ladder)trans-86.9139.1176.1-67.7-63.9000111I81 P83 V88 I108 D112 C114 I122 K134 E135 I136I81-F110 HydrophobicContact CD1-CE1 3.9Å; I81-F110 HydrophobicContact CG1-CD1 4Å; I81-F110 HydrophobicContact CG1-CE1 3.87Å; I81-F110 VanDerWaalsContact O-CA 3.27Å; I81-F110 WeakPolarHBondContact O-CA 3.37Å; P83-F110 HydrophobicContact CB-CB 4.39Å; P83-F110 HydrophobicContact CB-CD1 3.73Å; P83-F110 HydrophobicContact CB-CE1 4.22Å; P83-F110 HydrophobicContact CB-CG 4.12Å; V88-F110 HydrophobicContact CG2-CE1 4.21Å; V88-F110 HydrophobicContact CG2-CZ 4.33Å; I108-F110 HydrophobicContact CG2-CD2 4.24Å; I108-F110 HydrophobicContact CG2-CE1 4.08Å; I108-F110 HydrophobicContact CG2-CE2 3.75Å; I108-F110 HydrophobicContact CG2-CZ 3.66Å; F110-D112 VanDerWaalsContact C-N 3.28Å; F110-D112 WeakPolarHBondContact CB-O 3.22Å; F110-C114 HydrophobicContact CD2-CB 3.81Å; F110-C114 HydrophobicContact CE2-CB 4.08Å; F110-C114 HydrophobicContact CG-CB 4.28Å; F110-I122 HydrophobicContact CE2-CD1 4.15Å; F110-I122 HydrophobicContact CZ-CD1 3.66Å; F110-K134 PolarHBondContact N-O 3.25Å; F110-E135 HydrophobicContact CB-CG 4.3Å; F110-I136 PolarHBondContact O-N 3.22Å
111T94.7Very high94.2Very high3 Ų342.3 Ų42.32%0.01821%0.212CC..SBendtrans-67-31.9175.957.10000112F40 T41 F80 I81 S82 N137 I138 S139F40-T111 HydrophobicContact CD1-CG2 3.98Å; F40-T111 HydrophobicContact CE1-CG2 3.79Å; T41-T111 HydrophobicContact CG2-CG2 3.29Å; F80-T111 HydrophobicContact CD2-CG2 4.46Å; F80-T111 HydrophobicContact CE2-CG2 3.84Å; F80-T111 HydrophobicContact CZ-CG2 4.13Å; I81-T111 PolarHBondContact O-N 2.87Å; I81-T111 VanDerWaalsContact O-N 3.09Å; S82-T111 WeakPolarHBondContact CA-OG1 3.45Å; T111-N137 CarbonylContact O-C 3.55Å; T111-N137 WeakPolarHBondContact O-CA 3.15Å; T111-N137 PolarHBondContact O-N 3.33Å; T111-I138 WeakPolarHBondContact CB-O 3.34Å; T111-I138 CarbonylContact O-C 3.53Å; T111-I138 PolarHBondContact O-N 3.16Å; T111-S139 PolarHBondContact O-OG 2.91Å
112D90Very high94.3Very high21 Ų2139.9 Ų39.911%0.11220%0.202CC..SBendtrans-135.1-178.9-178.4-139.5-36.8000111.5P83 F110 C114 S139P83-D112 HydrophobicContact CG-CB 4.11Å; F110-D112 VanDerWaalsContact C-N 3.28Å; F110-D112 WeakPolarHBondContact CB-O 3.22Å; D112-C114 PolarHBondContact O-N 2.91Å; D112-S139 WeakPolarHBondContact CB-OG 3.4Å; D112-S139 VanDerWaalsContact OD2-CB 3.24Å; D112-S139 WeakPolarHBondContact OD2-CB 3.44Å; D112-S139 PolarHBondContact OD2-OG 3.46Å
113F89Confident94.2Very high113 Ų11345 Ų4550%0.49622%0.224SC..PPolyproline II helixtrans-48.7126.3167.5178.4-102.2000111.6P83 P115P83-F113 VanDerWaalsContact CG-O 3.28Å; P83-F113 WeakPolarHBondContact CG-O 3.3Å; F113-P115 WeakPolarHBondContact O-CD 3.37Å
114C91.8Very high93.9Very high3 Ų349.1 Ų49.12%0.0226%0.259CS..PPolyproline II helixtrans-91.9117.1176.71800000110P83 F110 D112 D116 E135P83-C114 HydrophobicContact CB-CB 4.02Å; F110-C114 HydrophobicContact CD2-CB 3.81Å; F110-C114 HydrophobicContact CE2-CB 4.08Å; F110-C114 HydrophobicContact CG-CB 4.28Å; D112-C114 PolarHBondContact O-N 2.91Å; C114-D116 PolarHBondContact O-N 3.25Å; C114-E135 WeakPolarHBondContact CB-OE1 3.48Å; C114-E135 PolarHBondContact N-OE1 2.91Å
115P92.3Very high93.6Very high49 Ų4946.8 Ų46.832%0.31826%0.258SS..PPolyproline II helixtrans-53138.6175.8-26.633.8000112.6F113 S117 L118 F119F113-P115 WeakPolarHBondContact O-CD 3.37Å; P115-S117 PolarHBondContact O-N 3.23Å; P115-S117 VanDerWaalsContact O-N 3.08Å; P115-L118 HydrophobicContact CG-CD1 4.38Å; P115-L118 PolarHBondContact O-N 3.47Å; P115-F119 PolarHBondContact O-N 2.97Å
116D93.8Very high93Very high111 Ų11147.1 Ų47.159%0.59426%0.261SS*.Hα-helixtrans-53.7-34.4-179.3-76.7-27.6000112.8C114 L118 F119 N120C114-D116 PolarHBondContact O-N 3.25Å; D116-L118 PolarHBondContact O-N 2.94Å; D116-F119 PolarHBondContact O-N 3.45Å; D116-N120 VanDerWaalsContact O-CB 3.22Å; D116-N120 WeakPolarHBondContact O-CB 3.45Å; D116-N120 PolarHBondContact O-N 3.49Å; D116-N120 PolarHBondContact O-ND2 3.5Å
117S95.4Very high92.4Very high88 Ų8850.2 Ų50.262%0.61528%0.282SS*.Hα-helixtrans-60.7-43.8177.158.40000112.2P115 K121P115-S117 PolarHBondContact O-N 3.23Å; P115-S117 VanDerWaalsContact O-N 3.08Å; S117-K121 PolarHBondContact O-N 3.31Å
118L95.3Very high92Very high17 Ų1758.4 Ų58.49%0.08932%0.318CS..Hα-helixtrans-73.5-41.5177.3-64.6-176.1000111.3P83 P85 V88 P115 D116 N120 K121 I122P83-L118 WeakPolarHBondContact O-CD1 3.47Å; P85-L118 HydrophobicContact CB-CD2 4.34Å; P85-L118 HydrophobicContact CG-CD1 4.45Å; P85-L118 HydrophobicContact CG-CD2 4.3Å; V88-L118 HydrophobicContact CB-CD2 4.5Å; V88-L118 HydrophobicContact CG2-CB 4.31Å; V88-L118 HydrophobicContact CG2-CD1 4.19Å; P115-L118 HydrophobicContact CG-CD1 4.38Å; P115-L118 PolarHBondContact O-N 3.47Å; D116-L118 PolarHBondContact O-N 2.94Å; L118-N120 VanDerWaalsContact C-N 3.35Å; L118-N120 PolarHBondContact O-N 3.21Å; L118-K121 WeakPolarHBondContact O-CB 3.48Å; L118-K121 PolarHBondContact O-N 3.16Å; L118-I122 WeakPolarHBondContact O-CG1 3.17Å; L118-I122 PolarHBondContact O-N 3.07Å
119F94.2Very high91.7Very high83 Ų8358.8 Ų58.836%0.36432%0.32SS..Hα-helixtrans-61.2-43.4177.3-173.9-101000112P115 D116 K121 I122 K123P115-F119 PolarHBondContact O-N 2.97Å; D116-F119 PolarHBondContact O-N 3.45Å; F119-K121 VanDerWaalsContact C-N 3.32Å; F119-K121 PolarHBondContact O-N 3.43Å; F119-I122 WeakPolarHBondContact O-CB 3.31Å; F119-I122 PolarHBondContact O-N 2.73Å; F119-K123 PolarHBondContact O-N 3.26Å
120N94.6Very high91.5Very high89 Ų8960.2 Ų60.248%0.47633%0.328SS..Hα-helixtrans-64.2-36.6176.3-76.3-44.1000112.3D116 L118 I122 K123 A124D116-N120 VanDerWaalsContact O-CB 3.22Å; D116-N120 WeakPolarHBondContact O-CB 3.45Å; D116-N120 PolarHBondContact O-N 3.49Å; D116-N120 PolarHBondContact O-ND2 3.5Å; L118-N120 VanDerWaalsContact C-N 3.35Å; L118-N120 PolarHBondContact O-N 3.21Å; N120-I122 VanDerWaalsContact C-N 3.34Å; N120-I122 PolarHBondContact O-N 3.12Å; N120-K123 PolarHBondContact O-N 3.4Å; N120-A124 WeakPolarHBondContact O-CB 3.47Å; N120-A124 PolarHBondContact O-N 3.14Å
121K93.7Very high91.4Very high92 Ų9266.9 Ų66.940%0.435%0.353SS..Hα-helixtrans-60.1-44.2173.2-160.7-178.4-177171.20111.4D89 L92 S117 L118 F119 A124 S125D89-K121 WeakPolarHBondContact OD1-CE 3.47Å; D89-K121 IonicContact OD1-NZ 2.6Å; D89-K121 PolarHBondContact OD1-NZ 2.69Å; D89-K121 IonicContact OD2-NZ 3.67Å; L92-K121 HydrophobicContact CD1-CB 4.47Å; L92-K121 HydrophobicContact CD1-CD 3.67Å; L92-K121 HydrophobicContact CD1-CG 3.64Å; S117-K121 PolarHBondContact O-N 3.31Å; L118-K121 WeakPolarHBondContact O-CB 3.48Å; L118-K121 PolarHBondContact O-N 3.16Å; F119-K121 VanDerWaalsContact C-N 3.32Å; F119-K121 PolarHBondContact O-N 3.43Å; K121-A124 PolarHBondContact O-N 2.76Å; K121-S125 PolarHBondContact O-N 2.89Å; K121-S125 PolarHBondContact O-OG 3.04Å
122I93.1Very high91.3Very high4 Ų472.7 Ų72.72%0.02138%0.375CS..Hα-helixtrans-61.7-47.5175.8-67.8168.2000111.5V88 F91 L92 I108 F110 L118 F119 N120 A124 S125 C126 I130V88-I122 HydrophobicContact CG1-CD1 3.97Å; V88-I122 HydrophobicContact CG1-CG1 3.76Å; V88-I122 HydrophobicContact CG2-CD1 4.23Å; F91-I122 HydrophobicContact CD1-CG1 4.35Å; F91-I122 HydrophobicContact CE1-CG1 4.31Å; F91-I122 HydrophobicContact CE1-CG2 4.06Å; L92-I122 HydrophobicContact CD2-CG1 4.4Å; I108-I122 HydrophobicContact CD1-CG2 4.44Å; F110-I122 HydrophobicContact CE2-CD1 4.15Å; F110-I122 HydrophobicContact CZ-CD1 3.66Å; L118-I122 WeakPolarHBondContact O-CG1 3.17Å; L118-I122 PolarHBondContact O-N 3.07Å; F119-I122 WeakPolarHBondContact O-CB 3.31Å; F119-I122 PolarHBondContact O-N 2.73Å; N120-I122 VanDerWaalsContact C-N 3.34Å; N120-I122 PolarHBondContact O-N 3.12Å; I122-A124 VanDerWaalsContact C-N 3.32Å; I122-A124 PolarHBondContact O-N 3.35Å; I122-S125 PolarHBondContact O-N 2.77Å; I122-C126 PolarHBondContact O-N 3.15Å; I122-I130 HydrophobicContact CG2-CD1 3.28Å
123K90.9Very high91.5Very high133 Ų13374.1 Ų74.158%0.57839%0.386SS*.Hα-helixtrans-59.6-41.1-179.5-172.2177.8179.1-179.90112.2F119 N120 S127F119-K123 PolarHBondContact O-N 3.26Å; N120-K123 PolarHBondContact O-N 3.4Å; K123-S127 WeakPolarHBondContact O-CB 3.4Å; K123-S127 PolarHBondContact O-OG 3.07Å
124A89.9Confident91.8Very high89 Ų8973 Ų7374%0.73638%0.38SS*.Hα-helixtrans-69.1-38-179.300000113.2N120 K121 I122N120-A124 WeakPolarHBondContact O-CB 3.47Å; N120-A124 PolarHBondContact O-N 3.14Å; K121-A124 PolarHBondContact O-N 2.76Å; I122-A124 VanDerWaalsContact C-N 3.32Å; I122-A124 PolarHBondContact O-N 3.35Å
125S86.4Confident91.8Very high79 Ų7976 Ų7655%0.55239%0.394SS*.Hα-helixtrans-91.6-45.2-170-61.90000115K121 I122K121-S125 PolarHBondContact O-N 2.89Å; K121-S125 PolarHBondContact O-OG 3.04Å; I122-S125 PolarHBondContact O-N 2.77Å
126C83.4Confident91.8Very high7 Ų774 Ų745%0.04738%0.381CS..Hα-helixtrans-140.519.1-164.865.10000115.8F91 F95 I122 K128 S129F91-C126 WeakPolarHBondContact CE1-SG 3.37Å; F95-C126 HydrophobicContact CB-CB 3.79Å; I122-C126 PolarHBondContact O-N 3.15Å; C126-K128 PolarHBondContact O-N 2.88Å; C126-S129 WeakPolarHBondContact O-CB 3.35Å; C126-S129 PolarHBondContact O-N 3.45Å
127S82.3Confident91.7Very high64 Ų6470.3 Ų70.345%0.44836%0.361SS..G310 helixtrans-45.5-39.9-178.251.60000115.1K123 S129 I130K123-S127 WeakPolarHBondContact O-CB 3.4Å; K123-S127 PolarHBondContact O-OG 3.07Å; S127-S129 VanDerWaalsContact C-N 3.26Å; S127-S129 PolarHBondContact O-N 3.48Å; S127-I130 PolarHBondContact O-N 3.01Å
128K88.5Confident91.6Very high179 Ų17966.1 Ų66.178%0.77833%0.332SS*.G310 helixtrans-66.7-22.2-179.8-62.6-176.5-179.6-178.80114.5C126C126-K128 PolarHBondContact O-N 2.88Å
129S91.5Very high91.6Very high8 Ų865.6 Ų65.66%0.05633%0.329CS..G310 helixtrans-89.3-15.8179.8-55.20000112.4K101 A105 A106 C126 S127K101-S129 PolarHBondContact NZ-OG 2.86Å; A105-S129 CarbonylContact C-O 3.52Å; A105-S129 VanDerWaalsContact CA-O 3.26Å; A105-S129 WeakPolarHBondContact CA-O 3.5Å; A105-S129 WeakPolarHBondContact CB-O 3.39Å; A106-S129 PolarHBondContact N-O 3.16Å; C126-S129 WeakPolarHBondContact O-CB 3.35Å; C126-S129 PolarHBondContact O-N 3.45Å; S127-S129 VanDerWaalsContact C-N 3.26Å; S127-S129 PolarHBondContact O-N 3.48Å
130I94Very high91.8Very high31 Ų3161.6 Ų61.616%0.15931%0.312CS..EExtended strand (participates in β ladder)trans-86.5130.8-176.1-59.1172.3000109.2F91 A106 I108 I122 S127 R132 C133F91-I130 HydrophobicContact CE1-CD1 4.25Å; F91-I130 HydrophobicContact CZ-CD1 4.03Å; F91-I130 HydrophobicContact CZ-CG1 4.06Å; A106-I130 CarbonylContact O-C 3.57Å; A106-I130 WeakPolarHBondContact O-CA 3.4Å; I108-I130 HydrophobicContact CD1-CD1 3.68Å; I108-I130 HydrophobicContact CD1-CG1 3.95Å; I108-I130 HydrophobicContact CD1-CG2 4.14Å; I108-I130 HydrophobicContact CG1-CG2 4.45Å; I122-I130 HydrophobicContact CG2-CD1 3.28Å; S127-I130 PolarHBondContact O-N 3.01Å; I130-R132 VanDerWaalsContact CG2-O 3.26Å; I130-R132 WeakPolarHBondContact CG2-O 3.31Å; I130-C133 HydrophobicContact CG2-CB 4.19Å
131R94.2Very high91.9Very high142 Ų14258.1 Ų58.154%0.53629%0.293SS..EExtended strand (participates in β ladder)trans-100.8-34.7177.5-65.3-63.7-176.4-1263.7112.4A105 A106 Y107A105-R131 HydrophobicContact CB-CG 3.82Å; A106-R131 PolarHBondContact O-N 2.8Å; Y107-R131 HydrophobicContact CD1-CB 4Å; Y107-R131 HydrophobicContact CE1-CB 3.69Å
132R94Very high92.1Very high125 Ų12553.8 Ų53.847%0.47227%0.274SS..EExtended strand (participates in β ladder)trans-145.1145175.7-63.7-68.2-166164.47.4108.6D25 Y107 I108 I130D25-R132 IonicContact OD1-CZ 3.83Å; D25-R132 IonicContact OD1-NH2 3.81Å; D25-R132 IonicContact OD2-NE 2.8Å; Y107-R132 HydrophobicContact CD1-CB 3.84Å; Y107-R132 HydrophobicContact CD1-CG 3.62Å; Y107-R132 HydrophobicContact CE1-CG 3.99Å; I108-R132 PolarHBondContact N-O 2.85Å; I130-R132 VanDerWaalsContact CG2-O 3.26Å; I130-R132 WeakPolarHBondContact CG2-O 3.31Å
133C94.1Very high92.1Very high51 Ų5155.3 Ų55.335%0.34528%0.281SS..EExtended strand (participates in β ladder)trans-142114.6170.7-167.50000106.5I108 I130I108-C133 CarbonylContact O-C 3.44Å; I108-C133 VanDerWaalsContact O-CA 3.22Å; I108-C133 WeakPolarHBondContact O-CA 3.41Å; I130-C133 HydrophobicContact CG2-CB 4.19Å
134K94.4Very high92.4Very high88 Ų8849.1 Ų49.138%0.38326%0.255SS..EExtended strand (participates in β ladder)trans-143.4151.9-175.3-173.8171.3-176.9176.40111.3I108 Y109 F110I108-K134 PolarHBondContact O-N 3.39Å; Y109-K134 CarbonylContact C-O 3.59Å; Y109-K134 VanDerWaalsContact CA-O 3.28Å; Y109-K134 WeakPolarHBondContact CA-O 3.4Å; Y109-K134 HydrophobicContact CD1-CB 4.01Å; Y109-K134 HydrophobicContact CE1-CB 4.08Å; F110-K134 PolarHBondContact N-O 3.25Å
135E92.8Very high92.6Very high68 Ų6845.5 Ų45.532%0.31822%0.224SC..EExtended strand (participates in β ladder)trans-103.4139172.5-60.5168.9172.300109.2F110 C114F110-E135 HydrophobicContact CB-CG 4.3Å; C114-E135 WeakPolarHBondContact CB-OE1 3.48Å; C114-E135 PolarHBondContact N-OE1 2.91Å
136I91.4Very high93.1Very high7 Ų742.9 Ų42.94%0.03620%0.203CC..  trans-110.7-24-173.2-59.4161.7000112.5K17 T21 V22 F80 Y109 F110 I138K17-I136 WeakPolarHBondContact CE-O 3.25Å; K17-I136 HydrophobicContact CG-CG2 4.49Å; K17-I136 PolarHBondContact NZ-O 3.47Å; K17-I136 VanDerWaalsContact NZ-O 3.14Å; T21-I136 HydrophobicContact CG2-CG2 4.42Å; T21-I136 VanDerWaalsContact OG1-CG2 3.28Å; T21-I136 WeakPolarHBondContact OG1-CG2 3.46Å; V22-I136 HydrophobicContact CG2-CD1 3.23Å; V22-I136 HydrophobicContact CG2-CG1 4.37Å; F80-I136 HydrophobicContact CD2-CD1 4.07Å; F80-I136 HydrophobicContact CE2-CD1 3.71Å; Y109-I136 HydrophobicContact CD1-CD1 4.01Å; Y109-I136 HydrophobicContact CD1-CG1 4.36Å; Y109-I136 HydrophobicContact CG-CD1 4.2Å; F110-I136 PolarHBondContact O-N 3.22Å; I136-I138 HydrophobicContact CG2-CD1 3.59Å; I136-I138 HydrophobicContact CG2-CG1 3.9Å
137N90.8Very high93.8Very high32 Ų3242.5 Ų42.517%0.17120%0.2CC..  trans59.563.7-175.9-52.1-60.1000111.6K17 T111 T183 T187 Y218K17-N137 PolarHBondContact NZ-O 3.15Å; T111-N137 CarbonylContact O-C 3.55Å; T111-N137 WeakPolarHBondContact O-CA 3.15Å; T111-N137 PolarHBondContact O-N 3.33Å; N137-T183 HydrophobicContact CB-CG2 4.08Å; N137-T183 WeakPolarHBondContact O-CB 3.48Å; N137-T187 PolarHBondContact O-OG1 2.98Å; N137-Y218 HydrophobicContact CB-CE2 4.47Å
138I94.8Very high94.5Very high0 Ų039.5 Ų39.50%018%0.179CC..  trans-137.791.9168.8-57168.6000107.7V14 K17 I18 L44 T111 I136 F140V14-I138 HydrophobicContact CG1-CG2 4.18Å; K17-I138 HydrophobicContact CB-CD1 4.13Å; K17-I138 HydrophobicContact CD-CD1 3.72Å; K17-I138 HydrophobicContact CD-CG1 3.84Å; K17-I138 HydrophobicContact CG-CD1 3.87Å; I18-I138 HydrophobicContact CD1-CD1 4.48Å; I18-I138 HydrophobicContact CG1-CD1 3.72Å; L44-I138 HydrophobicContact CD1-CG2 4.11Å; L44-I138 HydrophobicContact CD2-CB 4.5Å; L44-I138 HydrophobicContact CD2-CG2 3.78Å; T111-I138 WeakPolarHBondContact CB-O 3.34Å; T111-I138 CarbonylContact O-C 3.53Å; T111-I138 PolarHBondContact O-N 3.16Å; I136-I138 HydrophobicContact CG2-CD1 3.59Å; I136-I138 HydrophobicContact CG2-CG1 3.9Å; I138-F140 HydrophobicContact CG2-CD1 4.44Å; I138-F140 HydrophobicContact CG2-CE1 4.21Å
139S95.2Very high95Very high6 Ų631.6 Ų31.64%0.04215%0.146CC..  trans-119.731.5-177.9-58.90000112.4T111 D112 Q180 T183T111-S139 PolarHBondContact O-OG 2.91Å; D112-S139 WeakPolarHBondContact CB-OG 3.4Å; D112-S139 VanDerWaalsContact OD2-CB 3.24Å; D112-S139 WeakPolarHBondContact OD2-CB 3.44Å; D112-S139 PolarHBondContact OD2-OG 3.46Å; S139-Q180 WeakPolarHBondContact O-CG 3.21Å; S139-Q180 PolarHBondContact O-NE2 3.33Å; S139-T183 PolarHBondContact N-OG1 2.84Å
140F97.6Very high95.3Very high0 Ų031.3 Ų31.30%014%0.144CC..SBendtrans-134.4164.5175.170-86.5000110.3L10 V14 L44 I138 P142 Y148 L150 V184 T187L10-F140 HydrophobicContact CD1-CE2 4.17Å; L10-F140 HydrophobicContact CD1-CZ 4.23Å; L10-F140 HydrophobicContact CD2-CE2 3.92Å; L10-F140 HydrophobicContact CG-CE2 4.13Å; V14-F140 HydrophobicContact CG2-CE2 3.82Å; V14-F140 HydrophobicContact CG2-CZ 3.6Å; L44-F140 WeakPolarHBondContact CD1-O 3.16Å; I138-F140 HydrophobicContact CG2-CD1 4.44Å; I138-F140 HydrophobicContact CG2-CE1 4.21Å; F140-P142 HydrophobicContact CE2-CB 4.43Å; F140-Y148 HydrophobicContact CD2-CG 4.49Å; F140-L150 HydrophobicContact CB-CD2 3.94Å; F140-V184 HydrophobicContact CB-CG2 3.84Å; F140-V184 HydrophobicContact CD1-CB 4.19Å; F140-V184 HydrophobicContact CD1-CG2 3.38Å; F140-V184 HydrophobicContact CD2-CG2 4.1Å; F140-V184 HydrophobicContact CE1-CB 4.25Å; F140-V184 HydrophobicContact CE1-CG2 3.9Å; F140-V184 HydrophobicContact CG-CG2 3.49Å; F140-V184 VanDerWaalsContact CG-CG2 3.49Å; F140-V184 HydrophobicContact CZ-CG2 4.43Å; F140-T187 HydrophobicContact CE1-CG2 4.19Å; F140-T187 HydrophobicContact CZ-CG2 3.91Å
141I97.2Very high95.3Very high16 Ų1632.5 Ų32.58%0.08215%0.151CC..EExtended strand (participates in β ladder)trans-107.1120.9176.8-54.2-61.3000109.5F40 R43 L44 H143 Y148 T149 D151F40-I141 HydrophobicContact CD2-CD1 4Å; F40-I141 HydrophobicContact CE2-CD1 3.5Å; F40-I141 VanDerWaalsContact CE2-CD1 3.5Å; F40-I141 HydrophobicContact CE2-CG1 3.99Å; F40-I141 HydrophobicContact CZ-CD1 3.99Å; R43-I141 HydrophobicContact CB-CD1 4.18Å; L44-I141 HydrophobicContact CB-CD1 3.81Å; L44-I141 HydrophobicContact CD1-CD1 4.32Å; I141-H143 PolarHBondContact O-N 3.21Å; I141-Y148 WeakPolarHBondContact O-CA 3.49Å; I141-T149 PolarHBondContact N-O 3.38Å; I141-T149 PolarHBondContact O-N 3.34Å; I141-D151 HydrophobicContact CG1-CB 4.22Å
142P96.6Very high95.4Very high0 Ų027.4 Ų27.40%014%0.135CC..EExtended strand (participates in β ladder)trans-74.4107.1169.732.5-34.8000109.5L10 K11 V14 L44 S47 C48 F140L10-P142 HydrophobicContact CB-CB 4.44Å; L10-P142 HydrophobicContact CD2-CB 4.16Å; L10-P142 HydrophobicContact CG-CB 3.95Å; K11-P142 WeakPolarHBondContact CE-O 3.47Å; K11-P142 HydrophobicContact CG-CB 3.84Å; K11-P142 HydrophobicContact CG-CG 4.11Å; V14-P142 HydrophobicContact CB-CG 4.08Å; V14-P142 HydrophobicContact CG1-CG 4.14Å; V14-P142 HydrophobicContact CG2-CB 4.19Å; V14-P142 HydrophobicContact CG2-CG 3.95Å; L44-P142 HydrophobicContact CD1-CG 4.5Å; S47-P142 WeakPolarHBondContact OG-CD 3.21Å; S47-P142 WeakPolarHBondContact OG-CG 3.25Å; C48-P142 HydrophobicContact CB-CG 4.45Å; F140-P142 HydrophobicContact CE2-CB 4.43Å
143H95Very high95.5Very high36 Ų3624.4 Ų24.417%0.16713%0.132CC..EExtended strand (participates in β ladder)trans-81.3-43-178-172.168.2000111.7K11 I141 V147 D267 I567K11-H143 WeakPolarHBondContact CE-O 3.24Å; K11-H143 PolarHBondContact NZ-O 3.11Å; I141-H143 PolarHBondContact O-N 3.21Å; H143-V147 HydrophobicContact CB-CB 4.5Å; H143-V147 HydrophobicContact CB-CG1 4.28Å; H143-V147 PolarHBondContact N-O 3.38Å; H143-D267 IonicContact CE1-OD2 3.65Å; H143-I567 HydrophobicContact CB-CD1 4.31Å; H143-I567 WeakPolarHBondContact CD2-CD1 2.99Å; H143-I567 WeakPolarHBondContact NE2-CD1 3.32Å
144E95.5Very high95.5Very high4 Ų426.3 Ų26.32%0.01914%0.139CC..EExtended strand (participates in β ladder)trans-140.7-179.6175.1-53-176.9155.800110.6Q146 V147 Q255 E284 R293 M545 Y549E144-Q146 PolarHBondContact O-N 3.29Å; E144-Q146 VanDerWaalsContact O-N 3.14Å; E144-V147 HydrophobicContact CB-CB 3.99Å; E144-V147 HydrophobicContact CB-CG2 4.14Å; E144-V147 HydrophobicContact CG-CB 4.26Å; E144-V147 HydrophobicContact CG-CG2 4.4Å; E144-V147 PolarHBondContact N-O 3.38Å; E144-V147 VanDerWaalsContact N-O 3.09Å; E144-V147 PolarHBondContact O-N 3.49Å; E144-Q255 PolarHBondContact OE1-NE2 2.93Å; E144-E284 HydrophobicContact CB-CG 4.32Å; E144-R293 IonicContact OE1-CZ 3.69Å; E144-R293 IonicContact OE1-NE 3.56Å; E144-R293 IonicContact OE1-NH1 3.67Å; E144-R293 PolarHBondContact OE1-NH1 2.68Å; E144-R293 IonicContact OE2-CZ 3.42Å; E144-R293 IonicContact OE2-NE 3.89Å; E144-R293 IonicContact OE2-NH1 2.75Å; E144-R293 IonicContact OE2-NH2 3.05Å; E144-R293 PolarHBondContact OE2-NH2 3.08Å; E144-M545 VanDerWaalsContact CD-CE 3.48Å; E144-M545 HydrophobicContact CG-CE 4.22Å; E144-M545 WeakPolarHBondContact OE1-CE 3.36Å; E144-Y549 WeakPolarHBondContact CB-OH 3.48Å; E144-Y549 WeakPolarHBondContact OE2-CE2 3.48Å; E144-Y549 PolarHBondContact OE2-OH 3.49Å
145S94.6Very high95.6Very high13 Ų1322.2 Ų22.29%0.09112%0.121CC..THydrogen-bonded Turntrans-54.6-31.8179-65.90000114L10 E284 Y549L10-S145 WeakPolarHBondContact CB-O 3.47Å; L10-S145 PolarHBondContact N-O 2.68Å; S145-E284 WeakPolarHBondContact CB-OE2 3.29Å; S145-E284 PolarHBondContact N-OE2 3.14Å; S145-E284 PolarHBondContact OG-OE2 2.92Å; S145-Y549 PolarHBondContact N-OH 2.94Å
146Q96.7Very high95.8Very high23 Ų2319 Ų1911%0.10711%0.106CC..THydrogen-bonded Turntrans-124.610.6-179.7-59.1-172.6-114.200113.3E144 Y549 S552 V560 I561 I562E144-Q146 PolarHBondContact O-N 3.29Å; E144-Q146 VanDerWaalsContact O-N 3.14Å; Q146-Y549 HydrophobicContact CB-CD1 4.41Å; Q146-Y549 HydrophobicContact CB-CE1 3.86Å; Q146-Y549 HydrophobicContact CB-CE2 4.25Å; Q146-Y549 HydrophobicContact CG-CD1 4.11Å; Q146-Y549 HydrophobicContact CG-CE1 3.68Å; Q146-Y549 PolarHBondContact N-OH 3.08Å; Q146-Y549 VanDerWaalsContact OE1-CE1 3.3Å; Q146-S552 VanDerWaalsContact NE2-CB 3.32Å; Q146-S552 PolarHBondContact NE2-OG 2.94Å; Q146-V560 PolarHBondContact NE2-O 3.05Å; Q146-I561 WeakPolarHBondContact O-CA 3.16Å; Q146-I562 PolarHBondContact O-N 3.41Å
147V98.2Very high96.1Very high0 Ų019.3 Ų19.30%011%0.107CC..EExtended strand (participates in β ladder)trans-126.3130.6-172.9-173.80000111.5H143 E144 I540 M545 Y549 I562H143-V147 HydrophobicContact CB-CB 4.5Å; H143-V147 HydrophobicContact CB-CG1 4.28Å; H143-V147 PolarHBondContact N-O 3.38Å; E144-V147 HydrophobicContact CB-CB 3.99Å; E144-V147 HydrophobicContact CB-CG2 4.14Å; E144-V147 HydrophobicContact CG-CB 4.26Å; E144-V147 HydrophobicContact CG-CG2 4.4Å; E144-V147 PolarHBondContact N-O 3.38Å; E144-V147 VanDerWaalsContact N-O 3.09Å; E144-V147 PolarHBondContact O-N 3.49Å; V147-I540 HydrophobicContact CG1-CD1 3.87Å; V147-M545 HydrophobicContact CB-CE 4.3Å; V147-M545 HydrophobicContact CG1-CE 3.97Å; V147-M545 HydrophobicContact CG1-CG 3.9Å; V147-M545 HydrophobicContact CG1-SD 4.11Å; V147-M545 HydrophobicContact CG2-CB 4.03Å; V147-M545 HydrophobicContact CG2-CE 3.96Å; V147-M545 HydrophobicContact CG2-CG 3.9Å; V147-Y549 HydrophobicContact CG2-CE2 3.94Å; V147-I562 CarbonylContact C-O 3.4Å; V147-I562 VanDerWaalsContact CA-O 3.23Å; V147-I562 WeakPolarHBondContact CA-O 3.38Å; V147-I562 HydrophobicContact CG2-CG2 3.94Å
148Y98.4Very high96.4Very high0 Ų019.4 Ų19.40%011%0.105CC..EExtended strand (participates in β ladder)trans-129.4156.3174.669.9-85.9000113.5L10 F140 I141 L150 V184 I533 I534 F535 I561 I562 G563 S564L10-Y148 HydrophobicContact CD2-CD1 4.41Å; L10-Y148 HydrophobicContact CD2-CG 4.45Å; F140-Y148 HydrophobicContact CD2-CG 4.49Å; I141-Y148 WeakPolarHBondContact O-CA 3.49Å; Y148-L150 HydrophobicContact CD2-CD2 4.22Å; Y148-L150 HydrophobicContact CE2-CD2 4.14Å; Y148-V184 HydrophobicContact CD1-CG1 4.41Å; Y148-V184 HydrophobicContact CD2-CG2 3.8Å; Y148-V184 HydrophobicContact CE1-CG1 4.15Å; Y148-V184 HydrophobicContact CE2-CG1 4.28Å; Y148-V184 HydrophobicContact CE2-CG2 3.73Å; Y148-V184 HydrophobicContact CG-CG2 4.46Å; Y148-I533 HydrophobicContact CE1-CG2 4.17Å; Y148-I534 PolarHBondContact OH-O 3.04Å; Y148-F535 AromaticContact CE2-CD2 3.94Å; Y148-F535 HydrophobicContact CE2-CD2 3.94Å; Y148-F535 HydrophobicContact CE2-CE2 4.35Å; Y148-I561 HydrophobicContact CD1-CG2 3.67Å; Y148-I561 HydrophobicContact CE1-CG2 3.89Å; Y148-I562 VanDerWaalsContact CD1-O 3.31Å; Y148-I562 WeakPolarHBondContact CD1-O 3.26Å; Y148-I562 PolarHBondContact N-O 2.99Å; Y148-G563 VanDerWaalsContact CE1-N 3.35Å; Y148-G563 WeakPolarHBondContact O-CA 3.32Å; Y148-S564 PolarHBondContact O-N 3.32Å
149T98.2Very high96.5Very high14 Ų1419.5 Ų19.59%0.08611%0.106CC..EExtended strand (participates in β ladder)trans-131.3145172.762.70000111.2I141 D151 S564 I567I141-T149 PolarHBondContact N-O 3.38Å; I141-T149 PolarHBondContact O-N 3.34Å; T149-D151 VanDerWaalsContact C-N 3.29Å; T149-S564 CarbonylContact C-O 3.55Å; T149-S564 VanDerWaalsContact CA-O 3.27Å; T149-S564 WeakPolarHBondContact CA-O 3.19Å; T149-I567 HydrophobicContact CG2-CD1 4.15Å; T149-I567 HydrophobicContact CG2-CG1 3.87Å
150L98Very high96.6Very high1 Ų119.6 Ų19.61%0.00511%0.105CC..  trans-82.5-8.1172.1-55.8-170.8000113.2F140 Y148 V152 M177 Q180 I181 V184 F535 S564F140-L150 HydrophobicContact CB-CD2 3.94Å; Y148-L150 HydrophobicContact CD2-CD2 4.22Å; Y148-L150 HydrophobicContact CE2-CD2 4.14Å; L150-V152 VanDerWaalsContact C-N 3.35Å; L150-V152 HydrophobicContact CB-CG2 3.81Å; L150-V152 PolarHBondContact O-N 2.91Å; L150-M177 HydrophobicContact CD1-CB 3.95Å; L150-M177 HydrophobicContact CD1-CG 3.92Å; L150-Q180 HydrophobicContact CD1-CB 4.16Å; L150-Q180 HydrophobicContact CD2-CB 3.74Å; L150-Q180 HydrophobicContact CG-CB 4.35Å; L150-Q180 PolarHBondContact O-NE2 3.24Å; L150-I181 HydrophobicContact CD1-CD1 4.4Å; L150-I181 HydrophobicContact CD1-CG1 3.99Å; L150-V184 HydrophobicContact CD2-CG2 4.44Å; L150-F535 HydrophobicContact CD1-CE1 4.38Å; L150-F535 HydrophobicContact CD1-CE2 3.45Å; L150-F535 VanDerWaalsContact CD1-CE2 3.45Å; L150-F535 HydrophobicContact CD1-CZ 3.35Å; L150-F535 HydrophobicContact CD2-CE2 4.37Å; L150-F535 HydrophobicContact CG-CE2 3.63Å; L150-F535 HydrophobicContact CG-CZ 3.99Å; L150-S564 PolarHBondContact N-O 3.06Å
151D94.5Very high96.6Very high57 Ų5720.2 Ų20.231%0.30511%0.11SC..  trans59.143.2178.3-163.628.8000113R43 I141 T149 P153 T565R43-D151 IonicContact CZ-OD2 2.81Å; R43-D151 IonicContact NE-OD2 3.75Å; R43-D151 PolarHBondContact NE-OD2 2.87Å; R43-D151 IonicContact NH2-OD2 3.16Å; R43-D151 PolarHBondContact NH2-OD2 3.27Å; I141-D151 HydrophobicContact CG1-CB 4.22Å; T149-D151 VanDerWaalsContact C-N 3.29Å; D151-P153 VanDerWaalsContact C-CD 3.47Å; D151-T565 WeakPolarHBondContact CA-O 3.37Å; D151-T565 PolarHBondContact N-O 3.33Å
152V95.4Very high96.5Very high35 Ų3522.7 Ų22.721%0.21213%0.127CC..  trans-128.262.4-179-67.30000111L150 D154 A155 M177 T565L150-V152 VanDerWaalsContact C-N 3.35Å; L150-V152 HydrophobicContact CB-CG2 3.81Å; L150-V152 PolarHBondContact O-N 2.91Å; V152-D154 PolarHBondContact O-N 2.98Å; V152-D154 VanDerWaalsContact O-N 3.16Å; V152-A155 HydrophobicContact CB-CB 4.41Å; V152-A155 HydrophobicContact CG2-CB 4.07Å; V152-A155 WeakPolarHBondContact O-CB 3.04Å; V152-A155 PolarHBondContact O-N 2.97Å; V152-M177 HydrophobicContact CG2-CG 3.99Å; V152-M177 HydrophobicContact CG2-SD 4.31Å; V152-T565 HydrophobicContact CG2-CG2 3.91Å; V152-T565 PolarHBondContact N-O 2.85Å
153P95.2Very high96.4Very high61 Ų6125 Ų2540%0.39614%0.139SC..THydrogen-bonded Turntrans-57.4-33.6-176.523.4-34000112.9D151 A155 F156 H566D151-P153 VanDerWaalsContact C-CD 3.47Å; P153-A155 PolarHBondContact O-N 3.49Å; P153-F156 WeakPolarHBondContact O-CB 3.32Å; P153-F156 PolarHBondContact O-N 3.11Å; P153-H566 HydrophobicContact CB-CB 4.26Å
154D94.9Very high96.2Very high92 Ų9228.6 Ų28.649%0.49217%0.165SC..THydrogen-bonded Turntrans-58.9-20.1176.5-78-27.4000114.6V152 F156 Y157 Y158 K584V152-D154 PolarHBondContact O-N 2.98Å; V152-D154 VanDerWaalsContact O-N 3.16Å; D154-F156 PolarHBondContact O-N 3.4Å; D154-Y157 PolarHBondContact O-N 3.28Å; D154-Y158 HydrophobicContact CB-CD2 4.14Å; D154-Y158 HydrophobicContact CB-CE2 3.86Å; D154-Y158 WeakPolarHBondContact O-CD2 2.75Å; D154-Y158 PolarHBondContact O-N 2.9Å; D154-Y158 VanDerWaalsContact O-N 3.12Å; D154-K584 IonicContact OD1-NZ 2.96Å; D154-K584 PolarHBondContact OD1-NZ 3.13Å; D154-K584 IonicContact OD2-NZ 3.73Å
155A96Very high96Very high1 Ų132.5 Ų32.51%0.00819%0.193CC..Hα-helixtrans-59.8-30174.300000112.3V152 P153 Y158 C159 V173 M177 T565V152-A155 HydrophobicContact CB-CB 4.41Å; V152-A155 HydrophobicContact CG2-CB 4.07Å; V152-A155 WeakPolarHBondContact O-CB 3.04Å; V152-A155 PolarHBondContact O-N 2.97Å; P153-A155 PolarHBondContact O-N 3.49Å; A155-Y158 PolarHBondContact O-N 3.42Å; A155-C159 WeakPolarHBondContact O-CB 3.46Å; A155-C159 PolarHBondContact O-N 3.22Å; A155-C159 PolarHBondContact O-SG 3.35Å; A155-V173 HydrophobicContact CB-CG1 3.54Å; A155-M177 HydrophobicContact CB-SD 3.91Å; A155-T565 HydrophobicContact CB-CG2 3.73Å
156F97.9Very high95.9Very high2 Ų232.1 Ų32.11%0.00919%0.19CC..Hα-helixtrans-56.5-54.2173.9-175.2-93.7000110.9P153 D154 Y160 R240 L445 G538 L573 D576 I577 L580P153-F156 WeakPolarHBondContact O-CB 3.32Å; P153-F156 PolarHBondContact O-N 3.11Å; D154-F156 PolarHBondContact O-N 3.4Å; F156-Y160 AromaticContact CD2-CD2 3.86Å; F156-Y160 HydrophobicContact CD2-CD2 3.86Å; F156-Y160 HydrophobicContact CD2-CE2 4.06Å; F156-Y160 AromaticContact CE2-CD2 3.99Å; F156-Y160 HydrophobicContact CE2-CD2 3.99Å; F156-Y160 HydrophobicContact CE2-CE2 4.26Å; F156-Y160 HydrophobicContact CG-CD2 4.26Å; F156-Y160 HydrophobicContact CZ-CD2 4.47Å; F156-Y160 WeakPolarHBondContact O-CD2 3.43Å; F156-Y160 PolarHBondContact O-N 3.48Å; F156-Y160 VanDerWaalsContact O-N 3.16Å; F156-R240 HydrophobicContact CE2-CG 4.3Å; F156-L445 HydrophobicContact CE2-CD2 4.06Å; F156-L445 HydrophobicContact CZ-CD1 4.18Å; F156-L445 HydrophobicContact CZ-CD2 4.03Å; F156-G538 WeakPolarHBondContact CD2-O 3.44Å; F156-L573 HydrophobicContact CE2-CD1 3.67Å; F156-L573 HydrophobicContact CZ-CD1 3.66Å; F156-D576 HydrophobicContact CD1-CB 3.67Å; F156-D576 HydrophobicContact CE1-CB 3.72Å; F156-D576 HydrophobicContact CG-CB 4.5Å; F156-I577 HydrophobicContact CE1-CG1 3.98Å; F156-I577 HydrophobicContact CZ-CD1 4.43Å; F156-I577 HydrophobicContact CZ-CG1 3.62Å; F156-L580 HydrophobicContact CD1-CD2 3.97Å; F156-L580 HydrophobicContact CE1-CD1 3.99Å; F156-L580 HydrophobicContact CE1-CD2 3.78Å; F156-L580 HydrophobicContact CE1-CG 4.05Å; F156-L580 HydrophobicContact CZ-CD1 4.39Å
157Y97.5Very high95.7Very high13 Ų1333.9 Ų33.95%0.05121%0.209CC..Hα-helixtrans-60.3-51178.8177.6-92.1000111.9D154 C159 Y160 S161 N166 M579 L580 K582 K584D154-Y157 PolarHBondContact O-N 3.28Å; Y157-C159 PolarHBondContact O-N 3.07Å; Y157-Y160 PolarHBondContact O-N 2.86Å; Y157-S161 WeakPolarHBondContact O-CA 3.23Å; Y157-S161 WeakPolarHBondContact O-CB 3.34Å; Y157-S161 PolarHBondContact O-N 3.1Å; Y157-N166 VanDerWaalsContact CE1-ND2 3.31Å; Y157-N166 WeakPolarHBondContact CE1-ND2 3.08Å; Y157-N166 PolarHBondContact OH-ND2 3.36Å; Y157-M579 WeakPolarHBondContact CE2-O 3.49Å; Y157-L580 HydrophobicContact CD2-CD2 4.46Å; Y157-K582 VanDerWaalsContact CE2-O 3.29Å; Y157-K582 WeakPolarHBondContact CE2-O 3.46Å; Y157-K582 PolarHBondContact OH-O 3.27Å; Y157-K584 HydrophobicContact CD1-CD 3.52Å; Y157-K584 HydrophobicContact CD1-CG 3.95Å; Y157-K584 HydrophobicContact CD2-CG 4.39Å; Y157-K584 HydrophobicContact CE1-CB 4Å; Y157-K584 HydrophobicContact CE1-CD 3.63Å; Y157-K584 HydrophobicContact CE1-CG 3.65Å; Y157-K584 HydrophobicContact CE2-CG 4.13Å; Y157-K584 HydrophobicContact CG-CD 4.05Å; Y157-K584 HydrophobicContact CG-CG 4.3Å; Y157-K584 PolarHBondContact OH-N 3.01Å; Y157-K584 VanDerWaalsContact OH-N 3.15Å
158Y96.6Very high95.6Very high34 Ų3436.3 Ų36.313%0.13323%0.233CC..Hα-helixtrans-69.9-30.6-174.7-64.4-58000113.6D154 A155 N166 R169 K170 V173 K584D154-Y158 HydrophobicContact CB-CD2 4.14Å; D154-Y158 HydrophobicContact CB-CE2 3.86Å; D154-Y158 WeakPolarHBondContact O-CD2 2.75Å; D154-Y158 PolarHBondContact O-N 2.9Å; D154-Y158 VanDerWaalsContact O-N 3.12Å; A155-Y158 PolarHBondContact O-N 3.42Å; Y158-N166 HydrophobicContact CD1-CB 4.26Å; Y158-R169 HydrophobicContact CD1-CB 3.78Å; Y158-R169 HydrophobicContact CE1-CB 3.88Å; Y158-R169 VanDerWaalsContact CE1-CD 3.42Å; Y158-R169 HydrophobicContact CE1-CG 4.3Å; Y158-R169 HydrophobicContact CG-CB 4.3Å; Y158-K170 WeakPolarHBondContact O-CB 3.34Å; Y158-K170 WeakPolarHBondContact O-CD 3.44Å; Y158-K170 WeakPolarHBondContact O-CG 3.45Å; Y158-V173 HydrophobicContact CD2-CG2 3.9Å; Y158-K584 HydrophobicContact CE1-CD 4.19Å
159C97.1Very high95.4Very high2 Ų241.2 Ų41.21%0.01425%0.252CS..Hα-helixtrans-75.8-34.3177.9-67.40000112.8A155 Y157 K170 N203 I537A155-C159 WeakPolarHBondContact O-CB 3.46Å; A155-C159 PolarHBondContact O-N 3.22Å; A155-C159 PolarHBondContact O-SG 3.35Å; Y157-C159 PolarHBondContact O-N 3.07Å; C159-K170 PolarHBondContact O-NZ 2.71Å; C159-N203 PolarHBondContact O-ND2 3.26Å; C159-I537 HydrophobicContact CB-CG2 4.12Å
160Y97.9Very high95.3Very high7 Ų742.7 Ų42.73%0.02726%0.257CS..Hα-helixtrans-109.5-13.8-171.8-61-62.4000115.4F156 Y157 L201 N203 D239 R240 H444 L445 I537F156-Y160 AromaticContact CD2-CD2 3.86Å; F156-Y160 HydrophobicContact CD2-CD2 3.86Å; F156-Y160 HydrophobicContact CD2-CE2 4.06Å; F156-Y160 AromaticContact CE2-CD2 3.99Å; F156-Y160 HydrophobicContact CE2-CD2 3.99Å; F156-Y160 HydrophobicContact CE2-CE2 4.26Å; F156-Y160 HydrophobicContact CG-CD2 4.26Å; F156-Y160 HydrophobicContact CZ-CD2 4.47Å; F156-Y160 WeakPolarHBondContact O-CD2 3.43Å; F156-Y160 PolarHBondContact O-N 3.48Å; F156-Y160 VanDerWaalsContact O-N 3.16Å; Y157-Y160 PolarHBondContact O-N 2.86Å; Y160-L201 HydrophobicContact CD1-CD1 3.91Å; Y160-L201 HydrophobicContact CE1-CD1 3.72Å; Y160-N203 WeakPolarHBondContact CE1-ND2 3.25Å; Y160-D239 WeakPolarHBondContact CE1-OD1 3.44Å; Y160-D239 WeakPolarHBondContact OH-CA 3.42Å; Y160-D239 PolarHBondContact OH-OD1 3.48Å; Y160-R240 HydrophobicContact CE2-CB 4.18Å; Y160-R240 PolarHBondContact OH-N 2.91Å; Y160-H444 WeakPolarHBondContact O-CB 3.47Å; Y160-L445 HydrophobicContact CD1-CD1 4.45Å; Y160-L445 HydrophobicContact CD1-CG 4.06Å; Y160-L445 HydrophobicContact CD2-CG 4.37Å; Y160-L445 HydrophobicContact CE1-CG 4.42Å; Y160-L445 HydrophobicContact CG-CD1 4.14Å; Y160-L445 HydrophobicContact CG-CG 4.07Å; Y160-I537 HydrophobicContact CE2-CG2 4.45Å; Y160-I537 PolarHBondContact OH-O 2.8Å; Y160-I537 VanDerWaalsContact OH-O 3.11Å
161S96.4Very high95.2Very high14 Ų1448.8 Ų48.810%0.09829%0.286CS..  trans-58.4131.9176156.40000111Y157 D163 N166Y157-S161 WeakPolarHBondContact O-CA 3.23Å; Y157-S161 WeakPolarHBondContact O-CB 3.34Å; Y157-S161 PolarHBondContact O-N 3.1Å; S161-D163 PolarHBondContact O-N 3.38Å; S161-D163 WeakPolarHBondContact OG-CB 3.27Å; S161-D163 PolarHBondContact OG-N 3.05Å; S161-D163 VanDerWaalsContact OG-N 3.07Å; S161-N166 PolarHBondContact OG-ND2 3.29Å; S161-N166 VanDerWaalsContact OG-ND2 3.08Å
162P95.6Very high95.3Very high68 Ų6849 Ų4944%0.44230%0.295SS..  trans-74.7-12173.234.1-38.2000113.4P164 L580P162-P164 WeakPolarHBondContact O-CD 3.47Å; P162-L580 WeakPolarHBondContact CD-O 3.39Å
163D94.1Very high95.3Very high49 Ų4948.8 Ų48.826%0.26229%0.294SS..  trans-65115.1-178.8-175.4-14.7000111.6S161 S165 N166S161-D163 PolarHBondContact O-N 3.38Å; S161-D163 WeakPolarHBondContact OG-CB 3.27Å; S161-D163 PolarHBondContact OG-N 3.05Å; S161-D163 VanDerWaalsContact OG-N 3.07Å; D163-S165 PolarHBondContact O-N 2.79Å; D163-S165 VanDerWaalsContact OD1-CB 3.26Å; D163-S165 WeakPolarHBondContact OD1-CB 3.25Å; D163-S165 PolarHBondContact OD1-N 3.48Å; D163-S165 PolarHBondContact OD1-OG 3.11Å; D163-S165 PolarHBondContact OD2-OG 3.41Å; D163-S165 VanDerWaalsContact OD2-OG 3.06Å; D163-N166 WeakPolarHBondContact O-CB 3.49Å; D163-N166 PolarHBondContact O-N 2.98Å
164P90.8Very high95.5Very high110 Ų11046.3 Ų46.371%0.71428%0.277SS*.G310 helixtrans-67-19.9-177.628.1-35.4000113.4P162 N166 A167P162-P164 WeakPolarHBondContact O-CD 3.47Å; P164-N166 PolarHBondContact O-N 3.13Å; P164-A167 WeakPolarHBondContact O-CB 3.33Å; P164-A167 PolarHBondContact O-N 3.1Å; P164-A167 VanDerWaalsContact O-N 3.15Å
165S92.8Very high95.5Very high86 Ų8644.7 Ų44.760%0.60127%0.267SS*.G310 helixtrans-63.7-20.4175.971.30000112.6D163 A167D163-S165 PolarHBondContact O-N 2.79Å; D163-S165 VanDerWaalsContact OD1-CB 3.26Å; D163-S165 WeakPolarHBondContact OD1-CB 3.25Å; D163-S165 PolarHBondContact OD1-N 3.48Å; D163-S165 PolarHBondContact OD1-OG 3.11Å; D163-S165 PolarHBondContact OD2-OG 3.41Å; D163-S165 VanDerWaalsContact OD2-OG 3.06Å; S165-A167 VanDerWaalsContact C-N 3.3Å; S165-A167 PolarHBondContact O-N 3.15Å
166N92.1Very high95.5Very high5 Ų546.5 Ų46.53%0.02728%0.282CS..G310 helixtrans-81.2-1.9177.8-71.6-44.6000113.9Y157 Y158 S161 D163 P164 G168 R169 K170Y157-N166 VanDerWaalsContact CE1-ND2 3.31Å; Y157-N166 WeakPolarHBondContact CE1-ND2 3.08Å; Y157-N166 PolarHBondContact OH-ND2 3.36Å; Y158-N166 HydrophobicContact CD1-CB 4.26Å; S161-N166 PolarHBondContact OG-ND2 3.29Å; S161-N166 VanDerWaalsContact OG-ND2 3.08Å; D163-N166 WeakPolarHBondContact O-CB 3.49Å; D163-N166 PolarHBondContact O-N 2.98Å; P164-N166 PolarHBondContact O-N 3.13Å; N166-G168 PolarHBondContact O-N 2.83Å; N166-R169 PolarHBondContact O-N 3.11Å; N166-K170 WeakPolarHBondContact O-CB 3.46Å; N166-K170 PolarHBondContact O-N 2.83Å
167A93.2Very high95.4Very high61 Ų6146.4 Ų46.450%0.50428%0.282SS..Hα-helixtrans-53.5-48.3-174.700000113.7P164 S165 R169 K170 E171P164-A167 WeakPolarHBondContact O-CB 3.33Å; P164-A167 PolarHBondContact O-N 3.1Å; P164-A167 VanDerWaalsContact O-N 3.15Å; S165-A167 VanDerWaalsContact C-N 3.3Å; S165-A167 PolarHBondContact O-N 3.15Å; A167-R169 PolarHBondContact O-N 3.05Å; A167-K170 WeakPolarHBondContact O-CB 3.22Å; A167-K170 PolarHBondContact O-N 3.44Å; A167-E171 PolarHBondContact O-N 3.26Å
168G94.8Very high95.5Very high50 Ų5045.8 Ų45.852%0.51528%0.279SS..Hα-helixtrans-67.5-34.5178.100000113.4N166 A172N166-G168 PolarHBondContact O-N 2.83Å; G168-A172 WeakPolarHBondContact O-CB 3.38Å; G168-A172 PolarHBondContact O-N 3.47Å
169R94.7Very high95.4Very high104 Ų10447.9 Ų47.939%0.39229%0.29SS..Hα-helixtrans-69.6-38175.1-66.2-178.8179.9164.7-6.2111.3Y158 N166 A167 A172 V173 D585Y158-R169 HydrophobicContact CD1-CB 3.78Å; Y158-R169 HydrophobicContact CE1-CB 3.88Å; Y158-R169 VanDerWaalsContact CE1-CD 3.42Å; Y158-R169 HydrophobicContact CE1-CG 4.3Å; Y158-R169 HydrophobicContact CG-CB 4.3Å; N166-R169 PolarHBondContact O-N 3.11Å; A167-R169 PolarHBondContact O-N 3.05Å; R169-A172 PolarHBondContact O-N 2.85Å; R169-V173 WeakPolarHBondContact O-CB 3.35Å; R169-V173 VanDerWaalsContact O-CG2 3.29Å; R169-V173 WeakPolarHBondContact O-CG2 3.36Å; R169-V173 PolarHBondContact O-N 3.04Å; R169-D585 IonicContact NH1-OD1 3.96Å; R169-D585 IonicContact NH2-OD1 2.81Å
170K96.1Very high95.4Very high44 Ų4448.9 Ų48.919%0.19130%0.295CS..Hα-helixtrans-61-47.1174.5179.2174179.6159.20111.2Y158 C159 N166 A167 V173 M174 N203Y158-K170 WeakPolarHBondContact O-CB 3.34Å; Y158-K170 WeakPolarHBondContact O-CD 3.44Å; Y158-K170 WeakPolarHBondContact O-CG 3.45Å; C159-K170 PolarHBondContact O-NZ 2.71Å; N166-K170 WeakPolarHBondContact O-CB 3.46Å; N166-K170 PolarHBondContact O-N 2.83Å; A167-K170 WeakPolarHBondContact O-CB 3.22Å; A167-K170 PolarHBondContact O-N 3.44Å; K170-V173 PolarHBondContact O-N 3.23Å; K170-M174 HydrophobicContact CD-CE 4.43Å; K170-M174 VanDerWaalsContact CE-CE 3.43Å; K170-M174 HydrophobicContact CG-CE 4.12Å; K170-M174 HydrophobicContact CG-SD 4.28Å; K170-M174 WeakPolarHBondContact O-CB 3.32Å; K170-M174 WeakPolarHBondContact O-CG 3.49Å; K170-M174 PolarHBondContact O-N 3.42Å; K170-N203 WeakPolarHBondContact CE-OD1 3.23Å; K170-N203 PolarHBondContact NZ-OD1 2.94Å
171E96.7Very high95.4Very high129 Ų12948.5 Ų48.560%0.60329%0.293SS*.Hα-helixtrans-60.5-49.1176.5-173.9173.5-167.100111.5A167 V173 M174 E175A167-E171 PolarHBondContact O-N 3.26Å; E171-V173 VanDerWaalsContact C-N 3.34Å; E171-V173 PolarHBondContact O-N 3.03Å; E171-M174 PolarHBondContact O-N 2.9Å; E171-E175 WeakPolarHBondContact O-CG 3.49Å; E171-E175 PolarHBondContact O-N 3.3Å
172A95.3Very high95.4Very high62 Ų6248.4 Ų48.451%0.51229%0.292SS..Hα-helixtrans-59.8-41.3178.100000113.1G168 R169 A176G168-A172 WeakPolarHBondContact O-CB 3.38Å; G168-A172 PolarHBondContact O-N 3.47Å; R169-A172 PolarHBondContact O-N 2.85Å; A172-A176 WeakPolarHBondContact O-CB 3.36Å; A172-A176 PolarHBondContact O-N 2.86Å
173V96.4Very high95.4Very high30 Ų3045.2 Ų45.218%0.18227%0.271CS..Hα-helixtrans-69.1-37.5176.9169.40000111.6A155 Y158 R169 K170 E171 A176 M177A155-V173 HydrophobicContact CB-CG1 3.54Å; Y158-V173 HydrophobicContact CD2-CG2 3.9Å; R169-V173 WeakPolarHBondContact O-CB 3.35Å; R169-V173 VanDerWaalsContact O-CG2 3.29Å; R169-V173 WeakPolarHBondContact O-CG2 3.36Å; R169-V173 PolarHBondContact O-N 3.04Å; K170-V173 PolarHBondContact O-N 3.23Å; E171-V173 VanDerWaalsContact C-N 3.34Å; E171-V173 PolarHBondContact O-N 3.03Å; V173-A176 PolarHBondContact O-N 2.75Å; V173-M177 HydrophobicContact CG1-CE 4.17Å; V173-M177 HydrophobicContact CG1-CG 4.41Å; V173-M177 HydrophobicContact CG1-SD 4.45Å; V173-M177 WeakPolarHBondContact O-CB 3.2Å; V173-M177 VanDerWaalsContact O-CG 3.3Å; V173-M177 WeakPolarHBondContact O-CG 3.27Å; V173-M177 PolarHBondContact O-N 2.96Å
174M97.9Very high95.6Very high9 Ų942.9 Ų42.94%0.04426%0.259CS..Hα-helixtrans-65.1-41.1175-76.3-177.3169.100112.3K170 E171 M177 A178 N203 K206 L207 L210K170-M174 HydrophobicContact CD-CE 4.43Å; K170-M174 VanDerWaalsContact CE-CE 3.43Å; K170-M174 HydrophobicContact CG-CE 4.12Å; K170-M174 HydrophobicContact CG-SD 4.28Å; K170-M174 WeakPolarHBondContact O-CB 3.32Å; K170-M174 WeakPolarHBondContact O-CG 3.49Å; K170-M174 PolarHBondContact O-N 3.42Å; E171-M174 PolarHBondContact O-N 2.9Å; M174-M177 HydrophobicContact CG-CE 4.14Å; M174-M177 PolarHBondContact O-N 3.4Å; M174-A178 WeakPolarHBondContact O-CB 3.18Å; M174-A178 PolarHBondContact O-N 3.02Å; M174-N203 HydrophobicContact CE-CB 3.64Å; M174-N203 WeakPolarHBondContact CE-OD1 3.12Å; M174-K206 HydrophobicContact SD-CB 4.04Å; M174-K206 HydrophobicContact SD-CD 4.38Å; M174-L207 WeakPolarHBondContact O-CD1 3.46Å; M174-L210 HydrophobicContact CB-CD1 3.81Å
175E96.4Very high95.8Very high58 Ų5837.6 Ų37.627%0.27123%0.225SC..Hα-helixtrans-61.7-47174.2-75.6-72.6178.100111.7E171 A178 E179 L210 K214E171-E175 WeakPolarHBondContact O-CG 3.49Å; E171-E175 PolarHBondContact O-N 3.3Å; E175-A178 WeakPolarHBondContact O-CB 3.43Å; E175-A178 PolarHBondContact O-N 3.49Å; E175-E179 PolarHBondContact O-N 3.48Å; E175-L210 HydrophobicContact CG-CD1 4.34Å; E175-L210 WeakPolarHBondContact OE1-CD2 3.37Å; E175-K214 WeakPolarHBondContact O-CE 3.43Å; E175-K214 WeakPolarHBondContact OE2-CE 3.48Å; E175-K214 IonicContact OE2-NZ 3.37Å; E175-K214 PolarHBondContact OE2-NZ 3.11Å
176A94.6Very high95.8Very high40 Ų4034.2 Ų34.233%0.33120%0.201SC..Hα-helixtrans-61.4-46.8176.700000111.7A172 V173 A178 E179 Q180A172-A176 WeakPolarHBondContact O-CB 3.36Å; A172-A176 PolarHBondContact O-N 2.86Å; V173-A176 PolarHBondContact O-N 2.75Å; A176-A178 VanDerWaalsContact C-N 3.27Å; A176-A178 PolarHBondContact O-N 3.12Å; A176-E179 PolarHBondContact O-N 3.24Å; A176-Q180 VanDerWaalsContact O-CG 3.29Å; A176-Q180 WeakPolarHBondContact O-CG 3.34Å; A176-Q180 PolarHBondContact O-N 3.48Å
177M97.7Very high95.9Very high0 Ų034.4 Ų34.40%020%0.203CC..Hα-helixtrans-59.4-40.1175.9-74.6-170-59.200111.7L150 V152 A155 V173 M174 Q180 I181 L207 F535 T565L150-M177 HydrophobicContact CD1-CB 3.95Å; L150-M177 HydrophobicContact CD1-CG 3.92Å; V152-M177 HydrophobicContact CG2-CG 3.99Å; V152-M177 HydrophobicContact CG2-SD 4.31Å; A155-M177 HydrophobicContact CB-SD 3.91Å; V173-M177 HydrophobicContact CG1-CE 4.17Å; V173-M177 HydrophobicContact CG1-CG 4.41Å; V173-M177 HydrophobicContact CG1-SD 4.45Å; V173-M177 WeakPolarHBondContact O-CB 3.2Å; V173-M177 VanDerWaalsContact O-CG 3.3Å; V173-M177 WeakPolarHBondContact O-CG 3.27Å; V173-M177 PolarHBondContact O-N 2.96Å; M174-M177 HydrophobicContact CG-CE 4.14Å; M174-M177 PolarHBondContact O-N 3.4Å; M177-Q180 PolarHBondContact O-N 2.85Å; M177-I181 WeakPolarHBondContact O-CB 3.35Å; M177-I181 WeakPolarHBondContact O-CD1 3.46Å; M177-I181 WeakPolarHBondContact O-CG1 3.48Å; M177-I181 PolarHBondContact O-N 3.44Å; M177-L207 HydrophobicContact CB-CD1 3.96Å; M177-L207 HydrophobicContact CE-CD1 4.41Å; M177-L207 HydrophobicContact CE-CD2 4.19Å; M177-F535 HydrophobicContact SD-CE1 4.34Å; M177-F535 HydrophobicContact SD-CZ 4.28Å; M177-T565 HydrophobicContact SD-CG2 3.46Å; M177-T565 WeakPolarHBondContact SD-CG2 3.26Å
178A98Very high95.8Very high0 Ų032 Ų320%018%0.181CC..Hα-helixtrans-62.3-44.3178.100000111.6M174 E175 A176 I181 V182 L207 L210 V211 K214M174-A178 WeakPolarHBondContact O-CB 3.18Å; M174-A178 PolarHBondContact O-N 3.02Å; E175-A178 WeakPolarHBondContact O-CB 3.43Å; E175-A178 PolarHBondContact O-N 3.49Å; A176-A178 VanDerWaalsContact C-N 3.27Å; A176-A178 PolarHBondContact O-N 3.12Å; A178-I181 PolarHBondContact O-N 2.67Å; A178-V182 WeakPolarHBondContact O-CG2 3.37Å; A178-V182 PolarHBondContact O-N 2.82Å; A178-L207 HydrophobicContact CB-CD1 3.99Å; A178-L210 HydrophobicContact CB-CB 3.63Å; A178-V211 HydrophobicContact CB-CG2 3.81Å; A178-K214 HydrophobicContact CB-CD 3.85Å
179E95.2Very high95.6Very high78 Ų7834.7 Ų34.736%0.36418%0.184SC..Hα-helixtrans-57.8-49.8174-71.8167.3-173.800111.2E175 A176 I181 V182 T183 K214E175-E179 PolarHBondContact O-N 3.48Å; A176-E179 PolarHBondContact O-N 3.24Å; E179-I181 VanDerWaalsContact C-N 3.34Å; E179-I181 PolarHBondContact O-N 3.02Å; E179-V182 WeakPolarHBondContact O-CB 3.05Å; E179-V182 PolarHBondContact O-N 3.05Å; E179-V182 VanDerWaalsContact O-N 3.09Å; E179-T183 WeakPolarHBondContact O-CG2 3.46Å; E179-T183 PolarHBondContact O-N 3.12Å; E179-K214 HydrophobicContact CB-CD 4.46Å; E179-K214 HydrophobicContact CG-CD 3.6Å; E179-K214 IonicContact OE1-NZ 2.98Å; E179-K214 PolarHBondContact OE1-NZ 3.37Å
180Q97.3Very high95.4Very high22 Ų2230.3 Ų30.310%0.10317%0.168CC..Hα-helixtrans-62.6-39.5179.8-60175.5-73.400112.2S139 L150 A176 M177 V182 T183 V184S139-Q180 WeakPolarHBondContact O-CG 3.21Å; S139-Q180 PolarHBondContact O-NE2 3.33Å; L150-Q180 HydrophobicContact CD1-CB 4.16Å; L150-Q180 HydrophobicContact CD2-CB 3.74Å; L150-Q180 HydrophobicContact CG-CB 4.35Å; L150-Q180 PolarHBondContact O-NE2 3.24Å; A176-Q180 VanDerWaalsContact O-CG 3.29Å; A176-Q180 WeakPolarHBondContact O-CG 3.34Å; A176-Q180 PolarHBondContact O-N 3.48Å; M177-Q180 PolarHBondContact O-N 2.85Å; Q180-V182 VanDerWaalsContact C-N 3.32Å; Q180-V182 PolarHBondContact O-N 3.31Å; Q180-T183 WeakPolarHBondContact O-CB 3.43Å; Q180-T183 PolarHBondContact O-N 2.94Å; Q180-T183 VanDerWaalsContact O-N 3.09Å; Q180-T183 PolarHBondContact O-OG1 3.37Å; Q180-V184 PolarHBondContact O-N 3.26Å; Q180-V184 VanDerWaalsContact O-N 3.07Å
181I98.3Very high95.2Very high0 Ų028.6 Ų28.60%016%0.161CC..Hα-helixtrans-64.1-37.6175.2-68.5163.9000111.2L150 M177 A178 E179 T183 V184 C185 L207 V211 L235 F535L150-I181 HydrophobicContact CD1-CD1 4.4Å; L150-I181 HydrophobicContact CD1-CG1 3.99Å; M177-I181 WeakPolarHBondContact O-CB 3.35Å; M177-I181 WeakPolarHBondContact O-CD1 3.46Å; M177-I181 WeakPolarHBondContact O-CG1 3.48Å; M177-I181 PolarHBondContact O-N 3.44Å; A178-I181 PolarHBondContact O-N 2.67Å; E179-I181 VanDerWaalsContact C-N 3.34Å; E179-I181 PolarHBondContact O-N 3.02Å; I181-T183 VanDerWaalsContact C-N 3.28Å; I181-T183 PolarHBondContact O-N 3.12Å; I181-V184 WeakPolarHBondContact O-CB 3.28Å; I181-V184 PolarHBondContact O-N 2.97Å; I181-V184 VanDerWaalsContact O-N 3.15Å; I181-C185 PolarHBondContact O-N 3.33Å; I181-C185 PolarHBondContact O-SG 3.01Å; I181-L207 HydrophobicContact CD1-CD1 4.34Å; I181-L207 HydrophobicContact CD1-CD2 3.96Å; I181-L207 HydrophobicContact CD1-CG 4.29Å; I181-V211 HydrophobicContact CB-CG2 4.06Å; I181-V211 HydrophobicContact CD1-CG2 3.96Å; I181-V211 HydrophobicContact CG2-CG1 3.9Å; I181-V211 HydrophobicContact CG2-CG2 3.98Å; I181-L235 HydrophobicContact CG2-CD2 3.66Å; I181-F535 HydrophobicContact CD1-CD1 3.62Å; I181-F535 HydrophobicContact CD1-CD2 4.16Å; I181-F535 HydrophobicContact CD1-CE1 3.8Å; I181-F535 HydrophobicContact CD1-CE2 4.32Å; I181-F535 HydrophobicContact CD1-CG 3.81Å; I181-F535 HydrophobicContact CD1-CZ 4.14Å; I181-F535 HydrophobicContact CG1-CD2 4.23Å; I181-F535 HydrophobicContact CG1-CE2 4.37Å; I181-F535 HydrophobicContact CG1-CG 4.31Å
182V96Very high95.1Very high11 Ų1122.5 Ų22.57%0.06713%0.132CC..Hα-helixtrans-60.5-40.6171.7173.10000110.6A178 E179 Q180 V184 C185 A186 K214 L215 Y218A178-V182 WeakPolarHBondContact O-CG2 3.37Å; A178-V182 PolarHBondContact O-N 2.82Å; E179-V182 WeakPolarHBondContact O-CB 3.05Å; E179-V182 PolarHBondContact O-N 3.05Å; E179-V182 VanDerWaalsContact O-N 3.09Å; Q180-V182 VanDerWaalsContact C-N 3.32Å; Q180-V182 PolarHBondContact O-N 3.31Å; V182-V184 VanDerWaalsContact C-N 3.29Å; V182-V184 PolarHBondContact O-N 3.19Å; V182-C185 PolarHBondContact O-N 3.38Å; V182-A186 WeakPolarHBondContact O-CB 3.16Å; V182-A186 PolarHBondContact O-N 3.25Å; V182-K214 HydrophobicContact CG2-CB 3.57Å; V182-L215 HydrophobicContact CB-CD2 4.41Å; V182-L215 HydrophobicContact CG1-CD2 4.19Å; V182-L215 HydrophobicContact CG2-CD2 3.99Å; V182-L215 HydrophobicContact CG2-CG 3.96Å; V182-Y218 HydrophobicContact CG1-CD1 4.47Å; V182-Y218 HydrophobicContact CG1-CD2 4.23Å; V182-Y218 HydrophobicContact CG1-CG 3.97Å
183T95.6Very high94.9Very high1 Ų119.7 Ų19.71%0.00611%0.11CC..Hα-helixtrans-63.5-32.2175.376.80000113.5N137 S139 E179 Q180 I181 T187N137-T183 HydrophobicContact CB-CG2 4.08Å; N137-T183 WeakPolarHBondContact O-CB 3.48Å; S139-T183 PolarHBondContact N-OG1 2.84Å; E179-T183 WeakPolarHBondContact O-CG2 3.46Å; E179-T183 PolarHBondContact O-N 3.12Å; Q180-T183 WeakPolarHBondContact O-CB 3.43Å; Q180-T183 PolarHBondContact O-N 2.94Å; Q180-T183 VanDerWaalsContact O-N 3.09Å; Q180-T183 PolarHBondContact O-OG1 3.37Å; I181-T183 VanDerWaalsContact C-N 3.28Å; I181-T183 PolarHBondContact O-N 3.12Å; T183-T187 VanDerWaalsContact O-CB 3.25Å; T183-T187 WeakPolarHBondContact O-CB 3.35Å; T183-T187 PolarHBondContact O-N 3.47Å; T183-T187 PolarHBondContact O-OG1 3.43Å
184V97.3Very high94.9Very high0 Ų018.2 Ų18.20%010%0.101CC..Hα-helixtrans-63.1-52.4171.7177.20000109.8F140 Y148 L150 Q180 I181 V182 A186 T187 L188F140-V184 HydrophobicContact CB-CG2 3.84Å; F140-V184 HydrophobicContact CD1-CB 4.19Å; F140-V184 HydrophobicContact CD1-CG2 3.38Å; F140-V184 HydrophobicContact CD2-CG2 4.1Å; F140-V184 HydrophobicContact CE1-CB 4.25Å; F140-V184 HydrophobicContact CE1-CG2 3.9Å; F140-V184 HydrophobicContact CG-CG2 3.49Å; F140-V184 VanDerWaalsContact CG-CG2 3.49Å; F140-V184 HydrophobicContact CZ-CG2 4.43Å; Y148-V184 HydrophobicContact CD1-CG1 4.41Å; Y148-V184 HydrophobicContact CD2-CG2 3.8Å; Y148-V184 HydrophobicContact CE1-CG1 4.15Å; Y148-V184 HydrophobicContact CE2-CG1 4.28Å; Y148-V184 HydrophobicContact CE2-CG2 3.73Å; Y148-V184 HydrophobicContact CG-CG2 4.46Å; L150-V184 HydrophobicContact CD2-CG2 4.44Å; Q180-V184 PolarHBondContact O-N 3.26Å; Q180-V184 VanDerWaalsContact O-N 3.07Å; I181-V184 WeakPolarHBondContact O-CB 3.28Å; I181-V184 PolarHBondContact O-N 2.97Å; I181-V184 VanDerWaalsContact O-N 3.15Å; V182-V184 VanDerWaalsContact C-N 3.29Å; V182-V184 PolarHBondContact O-N 3.19Å; V184-A186 PolarHBondContact O-N 2.87Å; V184-T187 PolarHBondContact O-N 2.94Å; V184-T187 VanDerWaalsContact O-N 3.15Å; V184-L188 HydrophobicContact CG1-CD1 4.03Å; V184-L188 WeakPolarHBondContact O-CG 3.37Å; V184-L188 PolarHBondContact O-N 3.04Å
185C95.2Very high94.8Very high0 Ų017.9 Ų17.90%010%0.099CC..Hα-helixtrans-58.7-46.5179.4-60.40000111.5I181 V182 T187 L188 D189 E190 L215I181-C185 PolarHBondContact O-N 3.33Å; I181-C185 PolarHBondContact O-SG 3.01Å; V182-C185 PolarHBondContact O-N 3.38Å; C185-T187 VanDerWaalsContact C-N 3.32Å; C185-T187 PolarHBondContact O-N 3.32Å; C185-L188 PolarHBondContact O-N 3.25Å; C185-D189 PolarHBondContact O-N 3.15Å; C185-D189 VanDerWaalsContact O-N 3.07Å; C185-E190 WeakPolarHBondContact CB-O 3.46Å; C185-E190 PolarHBondContact O-N 2.57Å; C185-L215 HydrophobicContact CB-CD2 3.78Å
186A92.7Very high94.9Very high14 Ų1416.8 Ų16.812%0.1169%0.093CC..Hα-helixtrans-63.1-35.3176.800000112.9V182 V184 D189 Y218V182-A186 WeakPolarHBondContact O-CB 3.16Å; V182-A186 PolarHBondContact O-N 3.25Å; V184-A186 PolarHBondContact O-N 2.87Å; A186-D189 PolarHBondContact O-N 3.3Å; A186-Y218 HydrophobicContact CB-CD1 4.46Å; A186-Y218 HydrophobicContact CB-CE1 3.6Å; A186-Y218 HydrophobicContact CB-CE2 4.4Å; A186-Y218 WeakPolarHBondContact CB-OH 3.3Å
187T93.6Very high95Very high10 Ų1016.9 Ų16.96%0.0619%0.086CC..Hα-helixtrans-72.7-31.8177.7-620000112.4V13 V14 K17 N137 F140 T183 V184 C185V13-T187 HydrophobicContact CG1-CG2 4.02Å; V13-T187 WeakPolarHBondContact CG1-O 3.41Å; V14-T187 HydrophobicContact CG2-CG2 3.99Å; K17-T187 HydrophobicContact CD-CG2 3.92Å; K17-T187 PolarHBondContact NZ-OG1 3.32Å; N137-T187 PolarHBondContact O-OG1 2.98Å; F140-T187 HydrophobicContact CE1-CG2 4.19Å; F140-T187 HydrophobicContact CZ-CG2 3.91Å; T183-T187 VanDerWaalsContact O-CB 3.25Å; T183-T187 WeakPolarHBondContact O-CB 3.35Å; T183-T187 PolarHBondContact O-N 3.47Å; T183-T187 PolarHBondContact O-OG1 3.43Å; V184-T187 PolarHBondContact O-N 2.94Å; V184-T187 VanDerWaalsContact O-N 3.15Å; C185-T187 VanDerWaalsContact C-N 3.32Å; C185-T187 PolarHBondContact O-N 3.32Å
188L93Very high95Very high9 Ų918.7 Ų18.75%0.04710%0.098CC..Hα-helixtrans-79.6-8.3172.7-67.3172.4000113.3L10 V184 C185 E190 R531 I533 I561L10-L188 HydrophobicContact CD1-CD2 3.8Å; L10-L188 HydrophobicContact CD1-CG 4.46Å; V184-L188 HydrophobicContact CG1-CD1 4.03Å; V184-L188 WeakPolarHBondContact O-CG 3.37Å; V184-L188 PolarHBondContact O-N 3.04Å; C185-L188 PolarHBondContact O-N 3.25Å; L188-E190 HydrophobicContact CB-CB 4.25Å; L188-E190 HydrophobicContact CB-CG 3.77Å; L188-R531 PolarHBondContact O-NH1 3.33Å; L188-I533 HydrophobicContact CD1-CD1 3.71Å; L188-I533 HydrophobicContact CD1-CG1 4.1Å; L188-I561 HydrophobicContact CD1-CD1 3.7Å; L188-I561 HydrophobicContact CD2-CD1 3.56Å; L188-I561 HydrophobicContact CG-CD1 4.29Å
189D90.7Very high94.8Very high108 Ų10826.1 Ų26.158%0.57813%0.131SC*.THydrogen-bonded Turntrans59.243.9-170.7-165.838.6000112.2C185 A186 K228C185-D189 PolarHBondContact O-N 3.15Å; C185-D189 VanDerWaalsContact O-N 3.07Å; A186-D189 PolarHBondContact O-N 3.3Å; D189-K228 PolarHBondContact O-NZ 3.19Å; D189-K228 IonicContact OD1-NZ 3.78Å; D189-K228 PolarHBondContact OD1-NZ 3.35Å; D189-K228 IonicContact OD2-NZ 2.68Å; D189-K228 PolarHBondContact OD2-NZ 2.85Å
190E90.4Very high94.7Very high11 Ų1126.8 Ų26.85%0.05114%0.141CC..  trans-120.9133.2-174.7-68.5-65.4176.100112.2C185 L188 P192 Y219 T231 S233 R531 I533C185-E190 WeakPolarHBondContact CB-O 3.46Å; C185-E190 PolarHBondContact O-N 2.57Å; L188-E190 HydrophobicContact CB-CB 4.25Å; L188-E190 HydrophobicContact CB-CG 3.77Å; E190-P192 VanDerWaalsContact C-CD 3.45Å; E190-P192 VanDerWaalsContact O-CD 3.25Å; E190-P192 WeakPolarHBondContact O-CD 3.46Å; E190-Y219 PolarHBondContact O-OH 3.15Å; E190-T231 WeakPolarHBondContact OE2-CB 3.29Å; E190-T231 PolarHBondContact OE2-OG1 3.34Å; E190-S233 WeakPolarHBondContact OE2-CB 3.22Å; E190-S233 PolarHBondContact OE2-OG 3.24Å; E190-R531 IonicContact OE1-CZ 3.51Å; E190-R531 IonicContact OE1-NE 3.05Å; E190-R531 IonicContact OE1-NH1 2.68Å; E190-R531 PolarHBondContact OE1-NH1 3.18Å; E190-I533 HydrophobicContact CB-CD1 4.38Å
191N91.6Very high94.7Very high9 Ų927.9 Ų27.95%0.04815%0.148CC..  trans-111.878168.1-174.15.1000108.9Y219 K228 G229 K230 T231N191-Y219 HydrophobicContact CB-CD2 3.7Å; N191-Y219 HydrophobicContact CB-CE2 3.43Å; N191-Y219 VanDerWaalsContact CB-CE2 3.43Å; N191-Y219 HydrophobicContact CB-CG 4.38Å; N191-K228 PolarHBondContact ND2-O 2.92Å; N191-G229 PolarHBondContact ND2-O 2.82Å; N191-K230 CarbonylContact O-C 3.52Å; N191-K230 VanDerWaalsContact O-CA 3.28Å; N191-K230 WeakPolarHBondContact O-CA 3.4Å; N191-K230 WeakPolarHBondContact O-CD 3.47Å; N191-T231 HydrophobicContact CB-CG2 4.34Å; N191-T231 PolarHBondContact N-OG1 3.45Å; N191-T231 PolarHBondContact O-N 3.22Å; N191-T231 PolarHBondContact O-OG1 3.29Å
192P93.2Very high94.6Very high0 Ų031.6 Ų31.60%017%0.168CC..PPolyproline II helixtrans-72.1156-166.628-35.4000113.2E190 V194 L215 K230 S233 L235E190-P192 VanDerWaalsContact C-CD 3.45Å; E190-P192 VanDerWaalsContact O-CD 3.25Å; E190-P192 WeakPolarHBondContact O-CD 3.46Å; P192-V194 PolarHBondContact O-N 2.86Å; P192-L215 HydrophobicContact CG-CD1 4.21Å; P192-K230 WeakPolarHBondContact O-CD 3.41Å; P192-K230 PolarHBondContact O-NZ 3.05Å; P192-S233 WeakPolarHBondContact CA-O 3.05Å; P192-S233 WeakPolarHBondContact CA-OG 3.25Å; P192-S233 WeakPolarHBondContact CB-OG 3.47Å; P192-L235 HydrophobicContact CB-CB 3.95Å; P192-L235 HydrophobicContact CG-CB 3.81Å
193G92.6Very high94.7Very high3 Ų331.2 Ų31.23%0.03117%0.165CC..EExtended strand (participates in β ladder)trans-69.1117.4158.300000110S233 Q234 L235G193-S233 PolarHBondContact N-O 2.86Å; G193-Q234 WeakPolarHBondContact O-CA 3.36Å; G193-L235 PolarHBondContact O-N 3.5Å
194V95.8Very high94.9Very high0 Ų031.1 Ų31.10%017%0.165CC..EExtended strand (participates in β ladder)trans-88.1125.6-178.2-1750000110.3P192 A208 V211 E212 L215 L235 I237 Y497 C498P192-V194 PolarHBondContact O-N 2.86Å; V194-A208 HydrophobicContact CG1-CB 3.8Å; V194-V211 HydrophobicContact CG2-CG1 4.28Å; V194-E212 WeakPolarHBondContact CG2-OE2 3.15Å; V194-L215 HydrophobicContact CG2-CD1 3.73Å; V194-L235 HydrophobicContact CG1-CD2 4.4Å; V194-L235 HydrophobicContact CG2-CB 4.43Å; V194-L235 HydrophobicContact CG2-CD2 4.23Å; V194-I237 HydrophobicContact CG1-CD1 4.46Å; V194-Y497 WeakPolarHBondContact O-CA 3.42Å; V194-C498 HydrophobicContact CB-CB 4.39Å; V194-C498 PolarHBondContact O-N 2.91Å
195R96.1Very high94.9Very high1 Ų132.1 Ų32.10%0.00417%0.172CC..EExtended strand (participates in β ladder)trans-126.4160172-55.5175.374.6173.42.4110.1Q234 L235 L236 I237 L490 W495 P496 Y497R195-Q234 VanDerWaalsContact CD-OE1 3.23Å; R195-L235 PolarHBondContact N-O 3.02Å; R195-L236 HydrophobicContact CB-CD2 3.64Å; R195-L236 HydrophobicContact CG-CD2 4.13Å; R195-L236 WeakPolarHBondContact O-CA 3.25Å; R195-I237 PolarHBondContact O-N 3.05Å; R195-L490 PolarHBondContact NH2-O 2.69Å; R195-L490 VanDerWaalsContact NH2-O 3.14Å; R195-W495 VanDerWaalsContact CZ-O 3.31Å; R195-W495 PolarHBondContact NE-O 2.78Å; R195-W495 PolarHBondContact NH2-O 3.46Å; R195-P496 VanDerWaalsContact CA-O 3.29Å; R195-P496 WeakPolarHBondContact CA-O 3.32Å; R195-P496 WeakPolarHBondContact CB-O 3.32Å; R195-Y497 VanDerWaalsContact CD-CZ 3.49Å; R195-Y497 HydrophobicContact CG-CD1 3.37Å; R195-Y497 HydrophobicContact CG-CD2 4.25Å; R195-Y497 HydrophobicContact CG-CE1 3.41Å; R195-Y497 VanDerWaalsContact CG-CE1 3.41Å; R195-Y497 HydrophobicContact CG-CE2 4.29Å; R195-Y497 HydrophobicContact CG-CG 3.82Å
196Y97.9Very high95Very high35 Ų3536.1 Ų36.114%0.13719%0.189CC..EExtended strand (participates in β ladder)trans-144.8155.2177.958.3-89.6000111.5S198 S205 A208 I237 W495 P496Y196-S198 PolarHBondContact O-N 2.75Å; Y196-S205 VanDerWaalsContact CD2-CA 3.48Å; Y196-S205 WeakPolarHBondContact CE2-OG 3.35Å; Y196-A208 HydrophobicContact CD1-CB 3.56Å; Y196-A208 HydrophobicContact CE1-CB 4.48Å; Y196-A208 HydrophobicContact CG-CB 3.95Å; Y196-I237 CarbonylContact C-O 3.54Å; Y196-I237 VanDerWaalsContact CA-O 3.23Å; Y196-I237 WeakPolarHBondContact CA-O 3.47Å; Y196-W495 WeakPolarHBondContact O-CA 3.49Å; Y196-P496 HydrophobicContact CD2-CG 4.14Å; Y196-P496 HydrophobicContact CE1-CG 3.96Å; Y196-P496 HydrophobicContact CE2-CG 3.51Å; Y196-P496 VanDerWaalsContact CZ-CG 3.41Å; Y196-P496 PolarHBondContact N-O 2.72Å; Y196-P496 WeakPolarHBondContact O-CD 3.44Å
197K97.5Very high95.3Very high43 Ų4335.4 Ų35.419%0.18718%0.183CC..  trans-73.3122.4168-177.159.2172175.90109.4K199 I237 I238 E494 W495K197-K199 WeakPolarHBondContact CE-O 3.37Å; K197-K199 WeakPolarHBondContact CG-O 3.36Å; K197-I237 PolarHBondContact N-O 3.07Å; K197-I238 HydrophobicContact CB-CG2 4.15Å; K197-E494 IonicContact NZ-OE2 3.67Å; K197-E494 PolarHBondContact NZ-OE2 2.88Å; K197-W495 HydrophobicContact CB-CE3 4.17Å; K197-W495 HydrophobicContact CB-CH2 3.88Å; K197-W495 HydrophobicContact CB-CZ2 4.31Å; K197-W495 HydrophobicContact CB-CZ3 3.82Å; K197-W495 HydrophobicContact CD-CD2 4.24Å; K197-W495 HydrophobicContact CD-CH2 4.2Å; K197-W495 HydrophobicContact CD-CZ2 3.74Å; K197-W495 HydrophobicContact CG-CH2 4.38Å; K197-W495 HydrophobicContact CG-CZ2 4.39Å
198S96.4Very high95.5Very high38 Ų3835 Ų3527%0.26618%0.181SC..  trans-82.9-18.7-169.963.90000116Y196 K493 E494Y196-S198 PolarHBondContact O-N 2.75Å; S198-K493 PolarHBondContact OG-O 3.35Å; S198-E494 PolarHBondContact N-O 3.04Å; S198-E494 PolarHBondContact OG-O 3.36Å
199K94.9Very high95.8Very high156 Ų15639.8 Ų39.868%0.67820%0.203SC*.SBendtrans-145155-175.2-73.4-172.1179.6-177.20110.4K197K197-K199 WeakPolarHBondContact CE-O 3.37Å; K197-K199 WeakPolarHBondContact CG-O 3.36Å
200P93.3Very high96.1Very high91 Ų9136.4 Ų36.459%0.59118%0.184SC*.SBendcis-84.2-21.24.831.8-35.2000114.9G446P200-G446 WeakPolarHBondContact CG-O 3.26Å
201L96.9Very high96.5Very high45 Ų4535.9 Ų35.924%0.23618%0.182CC..  trans-100168.7-179.2-60.6-178.3000112Y160Y160-L201 HydrophobicContact CD1-CD1 3.91Å; Y160-L201 HydrophobicContact CE1-CD1 3.72Å
202D96.8Very high96.6Very high78 Ų7836 Ų3642%0.41718%0.182SC..SBendtrans-1093-176.572.8-0.8000114.4A204 S205 K206D202-A204 PolarHBondContact O-N 2.87Å; D202-S205 PolarHBondContact O-N 3.44Å; D202-K206 WeakPolarHBondContact O-CG 3.4Å; D202-K206 PolarHBondContact O-N 3.18Å; D202-K206 IonicContact OD1-NZ 3.2Å; D202-K206 PolarHBondContact OD1-NZ 3.09Å; D202-K206 WeakPolarHBondContact OD2-CE 3.21Å; D202-K206 IonicContact OD2-NZ 3.66Å; D202-K206 PolarHBondContact OD2-NZ 2.84Å
203N98.2Very high96.7Very high3 Ų342.3 Ų42.32%0.01621%0.21CC..Hα-helixtrans-64.5-43.9-178.3-55.7-46.1000110.9C159 Y160 K170 M174 S205 K206 L207 D239 I537C159-N203 PolarHBondContact O-ND2 3.26Å; Y160-N203 WeakPolarHBondContact CE1-ND2 3.25Å; K170-N203 WeakPolarHBondContact CE-OD1 3.23Å; K170-N203 PolarHBondContact NZ-OD1 2.94Å; M174-N203 HydrophobicContact CE-CB 3.64Å; M174-N203 WeakPolarHBondContact CE-OD1 3.12Å; N203-S205 VanDerWaalsContact C-N 3.3Å; N203-S205 PolarHBondContact O-N 2.68Å; N203-K206 PolarHBondContact O-N 3.22Å; N203-L207 WeakPolarHBondContact O-CB 3.33Å; N203-L207 PolarHBondContact O-N 3.18Å; N203-D239 VanDerWaalsContact CB-OD1 3.26Å; N203-D239 WeakPolarHBondContact CB-OD1 3.47Å; N203-D239 PolarHBondContact ND2-OD1 3.19Å; N203-I537 HydrophobicContact CB-CD1 3.9Å
204A98.4Very high96.7Very high0 Ų044 Ų440%022%0.216CC..Hα-helixtrans-58.6-41.9176.700000112.2D202 A208 I237 D239 I537D202-A204 PolarHBondContact O-N 2.87Å; A204-A208 WeakPolarHBondContact O-CB 3.3Å; A204-A208 PolarHBondContact O-N 2.94Å; A204-I237 HydrophobicContact CB-CG2 4.12Å; A204-D239 WeakPolarHBondContact CB-OD2 3.35Å; A204-D239 PolarHBondContact N-OD2 3.41Å; A204-I537 HydrophobicContact CB-CD1 4.4Å
205S98Very high96.6Very high20 Ų2044 Ų4414%0.1422%0.216CC..Hα-helixtrans-63.6-49175.8-177.20000112.2Y196 D202 N203 A208 Q209Y196-S205 VanDerWaalsContact CD2-CA 3.48Å; Y196-S205 WeakPolarHBondContact CE2-OG 3.35Å; D202-S205 PolarHBondContact O-N 3.44Å; N203-S205 VanDerWaalsContact C-N 3.3Å; N203-S205 PolarHBondContact O-N 2.68Å; S205-A208 PolarHBondContact O-N 3.29Å; S205-Q209 WeakPolarHBondContact O-CG 3.34Å; S205-Q209 PolarHBondContact O-N 3.21Å; S205-Q209 PolarHBondContact OG-NE2 3.18Å
206K98.1Very high96.3Very high84 Ų8448 Ų4837%0.36524%0.235SC..Hα-helixtrans-58.9-50.7178.3-74.7168.9176.2158.40111.5M174 D202 N203 A208 Q209 L210M174-K206 HydrophobicContact SD-CB 4.04Å; M174-K206 HydrophobicContact SD-CD 4.38Å; D202-K206 WeakPolarHBondContact O-CG 3.4Å; D202-K206 PolarHBondContact O-N 3.18Å; D202-K206 IonicContact OD1-NZ 3.2Å; D202-K206 PolarHBondContact OD1-NZ 3.09Å; D202-K206 WeakPolarHBondContact OD2-CE 3.21Å; D202-K206 IonicContact OD2-NZ 3.66Å; D202-K206 PolarHBondContact OD2-NZ 2.84Å; N203-K206 PolarHBondContact O-N 3.22Å; K206-A208 VanDerWaalsContact C-N 3.33Å; K206-A208 PolarHBondContact O-N 2.85Å; K206-Q209 PolarHBondContact O-N 3.35Å; K206-L210 WeakPolarHBondContact O-CG 3.27Å; K206-L210 PolarHBondContact O-N 3.29Å; K206-L210 VanDerWaalsContact O-N 3.13Å
207L98.6Very high95.9Very high0 Ų049.7 Ų49.70%025%0.246CC..Hα-helixtrans-62.3-41.5179.1-177.859.9000111.4M174 M177 A178 I181 N203 Q209 L210 V211 I237 F535 I537M174-L207 WeakPolarHBondContact O-CD1 3.46Å; M177-L207 HydrophobicContact CB-CD1 3.96Å; M177-L207 HydrophobicContact CE-CD1 4.41Å; M177-L207 HydrophobicContact CE-CD2 4.19Å; A178-L207 HydrophobicContact CB-CD1 3.99Å; I181-L207 HydrophobicContact CD1-CD1 4.34Å; I181-L207 HydrophobicContact CD1-CD2 3.96Å; I181-L207 HydrophobicContact CD1-CG 4.29Å; N203-L207 WeakPolarHBondContact O-CB 3.33Å; N203-L207 PolarHBondContact O-N 3.18Å; L207-Q209 VanDerWaalsContact C-N 3.33Å; L207-Q209 PolarHBondContact O-N 2.92Å; L207-L210 PolarHBondContact O-N 3.29Å; L207-V211 HydrophobicContact CD1-CG2 4.25Å; L207-V211 HydrophobicContact CG-CG2 4.36Å; L207-V211 VanDerWaalsContact O-CG2 3.29Å; L207-V211 WeakPolarHBondContact O-CG2 3.41Å; L207-V211 PolarHBondContact O-N 2.92Å; L207-I237 HydrophobicContact CB-CG2 4.36Å; L207-I237 HydrophobicContact CD2-CD1 4.39Å; L207-I237 HydrophobicContact CD2-CG2 3.94Å; L207-I237 HydrophobicContact CG-CD1 4.09Å; L207-I237 HydrophobicContact CG-CG2 4.35Å; L207-F535 HydrophobicContact CD2-CD1 3.78Å; L207-F535 HydrophobicContact CD2-CE1 3.6Å; L207-I537 HydrophobicContact CB-CD1 4.14Å; L207-I537 HydrophobicContact CD2-CD1 3.73Å; L207-I537 HydrophobicContact CD2-CG1 3.72Å
208A98.2Very high95.5Very high0 Ų051.4 Ų51.40%025%0.252CS..Hα-helixtrans-64.7-35178.800000113.4V194 Y196 A204 S205 K206 E212 I237 C498V194-A208 HydrophobicContact CG1-CB 3.8Å; Y196-A208 HydrophobicContact CD1-CB 3.56Å; Y196-A208 HydrophobicContact CE1-CB 4.48Å; Y196-A208 HydrophobicContact CG-CB 3.95Å; A204-A208 WeakPolarHBondContact O-CB 3.3Å; A204-A208 PolarHBondContact O-N 2.94Å; S205-A208 PolarHBondContact O-N 3.29Å; K206-A208 VanDerWaalsContact C-N 3.33Å; K206-A208 PolarHBondContact O-N 2.85Å; A208-E212 WeakPolarHBondContact O-CB 3.18Å; A208-E212 PolarHBondContact O-N 3.36Å; A208-I237 HydrophobicContact CB-CB 4.48Å; A208-I237 HydrophobicContact CB-CD1 3.96Å; A208-I237 HydrophobicContact CB-CG1 4.48Å; A208-C498 VanDerWaalsContact C-SG 3.54Å; A208-C498 VanDerWaalsContact CB-SG 3.53Å; A208-C498 PolarHBondContact O-SG 3.07Å; A208-C498 VanDerWaalsContact O-SG 3.4Å
209Q97.8Very high94.9Very high111 Ų11150.2 Ų50.252%0.51924%0.242SC..Hα-helixtrans-67.7-41.9173.5-70171.623.500111.8S205 K206 L207 E212 K213S205-Q209 WeakPolarHBondContact O-CG 3.34Å; S205-Q209 PolarHBondContact O-N 3.21Å; S205-Q209 PolarHBondContact OG-NE2 3.18Å; K206-Q209 PolarHBondContact O-N 3.35Å; L207-Q209 VanDerWaalsContact C-N 3.33Å; L207-Q209 PolarHBondContact O-N 2.92Å; Q209-E212 PolarHBondContact O-N 3.16Å; Q209-K213 WeakPolarHBondContact O-CB 3.26Å; Q209-K213 PolarHBondContact O-N 3.3Å
210L98Very high94.1Very high36 Ų3648.5 Ų48.519%0.18824%0.235CC..Hα-helixtrans-62.5-46175.3-67.8176.6000111.5M174 E175 A178 K206 L207 K213 K214M174-L210 HydrophobicContact CB-CD1 3.81Å; E175-L210 HydrophobicContact CG-CD1 4.34Å; E175-L210 WeakPolarHBondContact OE1-CD2 3.37Å; A178-L210 HydrophobicContact CB-CB 3.63Å; K206-L210 WeakPolarHBondContact O-CG 3.27Å; K206-L210 PolarHBondContact O-N 3.29Å; K206-L210 VanDerWaalsContact O-N 3.13Å; L207-L210 PolarHBondContact O-N 3.29Å; L210-K213 PolarHBondContact O-N 3.31Å; L210-K214 WeakPolarHBondContact O-CG 3.3Å; L210-K214 PolarHBondContact O-N 3.32Å
211V97.5Very high92.8Very high0 Ų050.6 Ų50.60%024%0.239CC..Hα-helixtrans-61.9-46.5177172.30000111.2A178 I181 V194 L207 K213 K214 L215 L235 I237A178-V211 HydrophobicContact CB-CG2 3.81Å; I181-V211 HydrophobicContact CB-CG2 4.06Å; I181-V211 HydrophobicContact CD1-CG2 3.96Å; I181-V211 HydrophobicContact CG2-CG1 3.9Å; I181-V211 HydrophobicContact CG2-CG2 3.98Å; V194-V211 HydrophobicContact CG2-CG1 4.28Å; L207-V211 HydrophobicContact CD1-CG2 4.25Å; L207-V211 HydrophobicContact CG-CG2 4.36Å; L207-V211 VanDerWaalsContact O-CG2 3.29Å; L207-V211 WeakPolarHBondContact O-CG2 3.41Å; L207-V211 PolarHBondContact O-N 2.92Å; V211-K213 VanDerWaalsContact C-N 3.34Å; V211-K213 PolarHBondContact O-N 2.91Å; V211-K214 PolarHBondContact O-N 2.85Å; V211-L215 HydrophobicContact CG1-CD1 3.75Å; V211-L215 HydrophobicContact CG1-CG 4.13Å; V211-L215 WeakPolarHBondContact O-CB 3.28Å; V211-L215 VanDerWaalsContact O-CG 3.3Å; V211-L215 WeakPolarHBondContact O-CG 3.31Å; V211-L215 PolarHBondContact O-N 3.42Å; V211-L235 HydrophobicContact CG1-CD2 3.71Å; V211-I237 HydrophobicContact CB-CD1 4.47Å; V211-I237 HydrophobicContact CG2-CD1 4.11Å
212E94.9Very high90.9Very high11 Ų1151.5 Ų51.55%0.05125%0.245CC..Hα-helixtrans-59.1-46.5178.6-174.970.817300111.1V194 A208 Q209 K214 L215 E216 K230 C498 S499V194-E212 WeakPolarHBondContact CG2-OE2 3.15Å; A208-E212 WeakPolarHBondContact O-CB 3.18Å; A208-E212 PolarHBondContact O-N 3.36Å; Q209-E212 PolarHBondContact O-N 3.16Å; E212-K214 PolarHBondContact O-N 3.45Å; E212-L215 PolarHBondContact O-N 3.23Å; E212-E216 WeakPolarHBondContact O-CG 3.42Å; E212-E216 PolarHBondContact O-N 3.45Å; E212-K230 VanDerWaalsContact OE1-CE 3.27Å; E212-K230 WeakPolarHBondContact OE1-CE 3.37Å; E212-K230 IonicContact OE1-NZ 2.73Å; E212-K230 PolarHBondContact OE1-NZ 3.26Å; E212-K230 IonicContact OE2-NZ 3.69Å; E212-K230 PolarHBondContact OE2-NZ 3.49Å; E212-C498 HydrophobicContact CB-CB 3.89Å; E212-C498 HydrophobicContact CG-CB 3.87Å; E212-S499 WeakPolarHBondContact OE1-CB 3.43Å; E212-S499 PolarHBondContact OE1-OG 3.32Å
213K94.4Very high88.9Confident133 Ų13356.4 Ų56.458%0.57827%0.265SS*.Hα-helixtrans-59.3-47.8177-177.1-175.2174.6-1700111.8Q209 L210 V211 E216 D217Q209-K213 WeakPolarHBondContact O-CB 3.26Å; Q209-K213 PolarHBondContact O-N 3.3Å; L210-K213 PolarHBondContact O-N 3.31Å; V211-K213 VanDerWaalsContact C-N 3.34Å; V211-K213 PolarHBondContact O-N 2.91Å; K213-E216 WeakPolarHBondContact O-CB 3.29Å; K213-E216 PolarHBondContact O-N 3.19Å; K213-D217 PolarHBondContact O-N 3.11Å
214K93.8Very high86.9Confident38 Ų3862.1 Ų62.117%0.16530%0.295CS..Hα-helixtrans-68.8-34-179.5-68.7-177-166.9-80.80112.5E175 A178 E179 V182 L210 V211 E212 D217 Y218E175-K214 WeakPolarHBondContact O-CE 3.43Å; E175-K214 WeakPolarHBondContact OE2-CE 3.48Å; E175-K214 IonicContact OE2-NZ 3.37Å; E175-K214 PolarHBondContact OE2-NZ 3.11Å; A178-K214 HydrophobicContact CB-CD 3.85Å; E179-K214 HydrophobicContact CB-CD 4.46Å; E179-K214 HydrophobicContact CG-CD 3.6Å; E179-K214 IonicContact OE1-NZ 2.98Å; E179-K214 PolarHBondContact OE1-NZ 3.37Å; V182-K214 HydrophobicContact CG2-CB 3.57Å; L210-K214 WeakPolarHBondContact O-CG 3.3Å; L210-K214 PolarHBondContact O-N 3.32Å; V211-K214 PolarHBondContact O-N 2.85Å; E212-K214 PolarHBondContact O-N 3.45Å; K214-D217 PolarHBondContact O-N 2.99Å; K214-Y218 VanDerWaalsContact O-CB 3.27Å; K214-Y218 WeakPolarHBondContact O-CB 3.34Å; K214-Y218 PolarHBondContact O-N 3.34Å
215L92.7Very high84.7Confident0 Ų065.4 Ų65.40%033%0.33CS..Hα-helixtrans-64.2-42.7172.2-75.7172000111.3V182 C185 P192 V194 V211 E212 Y218 Y219V182-L215 HydrophobicContact CB-CD2 4.41Å; V182-L215 HydrophobicContact CG1-CD2 4.19Å; V182-L215 HydrophobicContact CG2-CD2 3.99Å; V182-L215 HydrophobicContact CG2-CG 3.96Å; C185-L215 HydrophobicContact CB-CD2 3.78Å; P192-L215 HydrophobicContact CG-CD1 4.21Å; V194-L215 HydrophobicContact CG2-CD1 3.73Å; V211-L215 HydrophobicContact CG1-CD1 3.75Å; V211-L215 HydrophobicContact CG1-CG 4.13Å; V211-L215 WeakPolarHBondContact O-CB 3.28Å; V211-L215 VanDerWaalsContact O-CG 3.3Å; V211-L215 WeakPolarHBondContact O-CG 3.31Å; V211-L215 PolarHBondContact O-N 3.42Å; E212-L215 PolarHBondContact O-N 3.23Å; L215-Y218 PolarHBondContact O-N 3.13Å; L215-Y219 HydrophobicContact CD2-CD2 4.45Å; L215-Y219 HydrophobicContact CD2-CE2 3.98Å; L215-Y219 VanDerWaalsContact O-CD2 3.32Å; L215-Y219 WeakPolarHBondContact O-CD2 3.44Å; L215-Y219 PolarHBondContact O-N 3.26Å
216E90.5Very high82.6Confident85 Ų8569.4 Ų69.440%0.39735%0.349SS..Hα-helixtrans-59.6-46.8174.3-75.9-173.8-164.200111.6E212 K213 K220E212-E216 WeakPolarHBondContact O-CG 3.42Å; E212-E216 PolarHBondContact O-N 3.45Å; K213-E216 WeakPolarHBondContact O-CB 3.29Å; K213-E216 PolarHBondContact O-N 3.19Å; E216-K220 VanDerWaalsContact O-CB 3.26Å; E216-K220 WeakPolarHBondContact O-CB 3.36Å; E216-K220 VanDerWaalsContact O-CD 3.32Å; E216-K220 WeakPolarHBondContact O-CD 3.44Å; E216-K220 WeakPolarHBondContact O-CG 3.17Å; E216-K220 PolarHBondContact O-N 3.15Å; E216-K220 IonicContact OE2-NZ 3.76Å; E216-K220 PolarHBondContact OE2-NZ 3.17Å
217D89.8Confident81Confident71 Ų7171.9 Ų71.938%0.3837%0.365SS..Hα-helixtrans-64.8-43.8-179.9-66.5-20.6000111.1K213 K214 Y219 K220 I221K213-D217 PolarHBondContact O-N 3.11Å; K214-D217 PolarHBondContact O-N 2.99Å; D217-Y219 PolarHBondContact O-N 3.48Å; D217-K220 PolarHBondContact O-N 2.95Å; D217-I221 VanDerWaalsContact O-CD1 3.29Å; D217-I221 WeakPolarHBondContact O-CD1 3.19Å; D217-I221 VanDerWaalsContact O-CG1 3.24Å; D217-I221 WeakPolarHBondContact O-CG1 3.46Å; D217-I221 PolarHBondContact O-N 3.05Å
218Y88.6Confident79.7Confident79 Ų7974 Ų7431%0.3137%0.374SS..Hα-helixtrans-59.3-48.1177.3-174.9-98.8000112.6N137 V182 A186 K214 L215 I221N137-Y218 HydrophobicContact CB-CE2 4.47Å; V182-Y218 HydrophobicContact CG1-CD1 4.47Å; V182-Y218 HydrophobicContact CG1-CD2 4.23Å; V182-Y218 HydrophobicContact CG1-CG 3.97Å; A186-Y218 HydrophobicContact CB-CD1 4.46Å; A186-Y218 HydrophobicContact CB-CE1 3.6Å; A186-Y218 HydrophobicContact CB-CE2 4.4Å; A186-Y218 WeakPolarHBondContact CB-OH 3.3Å; K214-Y218 VanDerWaalsContact O-CB 3.27Å; K214-Y218 WeakPolarHBondContact O-CB 3.34Å; K214-Y218 PolarHBondContact O-N 3.34Å; L215-Y218 PolarHBondContact O-N 3.13Å; Y218-I221 PolarHBondContact O-N 2.88Å
219Y84.4Confident78.9Confident13 Ų1376.3 Ų76.35%0.05140%0.398CS..Hα-helixtrans-85.6-10.6-176.8-71.8-61.4000114.8E190 N191 L215 D217 K228E190-Y219 PolarHBondContact O-OH 3.15Å; N191-Y219 HydrophobicContact CB-CD2 3.7Å; N191-Y219 HydrophobicContact CB-CE2 3.43Å; N191-Y219 VanDerWaalsContact CB-CE2 3.43Å; N191-Y219 HydrophobicContact CB-CG 4.38Å; L215-Y219 HydrophobicContact CD2-CD2 4.45Å; L215-Y219 HydrophobicContact CD2-CE2 3.98Å; L215-Y219 VanDerWaalsContact O-CD2 3.32Å; L215-Y219 WeakPolarHBondContact O-CD2 3.44Å; L215-Y219 PolarHBondContact O-N 3.26Å; D217-Y219 PolarHBondContact O-N 3.48Å; Y219-K228 HydrophobicContact CD1-CB 3.75Å; Y219-K228 HydrophobicContact CD1-CD 3.85Å; Y219-K228 HydrophobicContact CD1-CG 4.29Å; Y219-K228 HydrophobicContact CE1-CB 4.37Å; Y219-K228 HydrophobicContact CE1-CD 3.56Å; Y219-K228 HydrophobicContact CE1-CG 4.45Å; Y219-K228 HydrophobicContact CG-CB 4.3Å
220K78.1Confident78.4Confident120 Ų12073.2 Ų73.252%0.52238%0.383SS..Hα-helixtrans-73.7-28.3166.5-79.3166.2-166.7160.50112.2E216 D217E216-K220 VanDerWaalsContact O-CB 3.26Å; E216-K220 WeakPolarHBondContact O-CB 3.36Å; E216-K220 VanDerWaalsContact O-CD 3.32Å; E216-K220 WeakPolarHBondContact O-CD 3.44Å; E216-K220 WeakPolarHBondContact O-CG 3.17Å; E216-K220 PolarHBondContact O-N 3.15Å; E216-K220 IonicContact OE2-NZ 3.76Å; E216-K220 PolarHBondContact OE2-NZ 3.17Å; D217-K220 PolarHBondContact O-N 2.95Å
221I64.7Low77.9Confident135 Ų13572.2 Ų72.269%0.69238%0.378SS*.SBendtrans-88.7-2-172.7-64.3167.5000112.8D217 Y218 E223D217-I221 VanDerWaalsContact O-CD1 3.29Å; D217-I221 WeakPolarHBondContact O-CD1 3.19Å; D217-I221 VanDerWaalsContact O-CG1 3.24Å; D217-I221 WeakPolarHBondContact O-CG1 3.46Å; D217-I221 PolarHBondContact O-N 3.05Å; Y218-I221 PolarHBondContact O-N 2.88Å; I221-E223 PolarHBondContact O-N 2.91Å
222D58.1Low77.3Confident65 Ų6575 Ų7535%0.34839%0.391SS..  trans-51.7136.1-171.3-172.437.9000114.1N224 G225D222-N224 PolarHBondContact O-N 3.43Å; D222-G225 PolarHBondContact O-N 3.26Å
223E54.1Low77.1Confident180 Ų18074.6 Ų74.684%0.84139%0.389SS*.THydrogen-bonded Turntrans-58.7-20.1-166-65.5-178.4161.400113.7I221I221-E223 PolarHBondContact O-N 2.91Å
224N55.6Low77.1Confident123 Ų12368.3 Ų68.366%0.65836%0.362SS*.THydrogen-bonded Turntrans-96.1-0.9-178.6-64.2-47.3000114.2D222 L226D222-N224 PolarHBondContact O-N 3.43Å; N224-L226 HydrophobicContact CB-CD1 4.3Å; N224-L226 HydrophobicContact CB-CG 4.42Å; N224-L226 PolarHBondContact O-N 3.33Å; N224-L226 VanDerWaalsContact O-N 3.1Å
225G52.4Low77.3Confident70 Ų7066.5 Ų66.572%0.72235%0.354SS*.SBendtrans65.47.7-174.200000114.2D222D222-G225 PolarHBondContact O-N 3.26Å
226L54.7Low77.6Confident103 Ų10366.5 Ų66.554%0.53935%0.354SS..  trans-88.4105.6172.5-69.2168.7000107.4N224 K228N224-L226 HydrophobicContact CB-CD1 4.3Å; N224-L226 HydrophobicContact CB-CG 4.42Å; N224-L226 PolarHBondContact O-N 3.33Å; N224-L226 VanDerWaalsContact O-N 3.1Å; L226-K228 PolarHBondContact O-N 3.42Å
227I64.4Low78Confident136 Ų13662.5 Ų62.570%0.69734%0.335SS*.  trans-58.8108.4172.1-60.1170.1000107.6G229I227-G229 PolarHBondContact O-N 2.76Å
228K72.1Confident78.4Confident45 Ų4559.1 Ų59.120%0.19632%0.317CS..  trans-69.3105175.1-169.7178.5-177.6-176.60108.4D189 N191 Y219 L226D189-K228 PolarHBondContact O-NZ 3.19Å; D189-K228 IonicContact OD1-NZ 3.78Å; D189-K228 PolarHBondContact OD1-NZ 3.35Å; D189-K228 IonicContact OD2-NZ 2.68Å; D189-K228 PolarHBondContact OD2-NZ 2.85Å; N191-K228 PolarHBondContact ND2-O 2.92Å; Y219-K228 HydrophobicContact CD1-CB 3.75Å; Y219-K228 HydrophobicContact CD1-CD 3.85Å; Y219-K228 HydrophobicContact CD1-CG 4.29Å; Y219-K228 HydrophobicContact CE1-CB 4.37Å; Y219-K228 HydrophobicContact CE1-CD 3.56Å; Y219-K228 HydrophobicContact CE1-CG 4.45Å; Y219-K228 HydrophobicContact CG-CB 4.3Å; L226-K228 PolarHBondContact O-N 3.42Å
229G80.8Confident78.9Confident48 Ų4855.9 Ų55.950%0.49531%0.305SS..PPolyproline II helixtrans-60.9170.1175.400000112.5N191 I227 T231N191-G229 PolarHBondContact ND2-O 2.82Å; I227-G229 PolarHBondContact O-N 2.76Å; G229-T231 PolarHBondContact O-N 3.09Å
230K86.6Confident79.5Confident47 Ų4755.2 Ų55.220%0.20430%0.303CS..PPolyproline II helixtrans-56.7130.1173.4-67.1-66.2-170.4177.80109.8N191 P192 E212 A503N191-K230 CarbonylContact O-C 3.52Å; N191-K230 VanDerWaalsContact O-CA 3.28Å; N191-K230 WeakPolarHBondContact O-CA 3.4Å; N191-K230 WeakPolarHBondContact O-CD 3.47Å; P192-K230 WeakPolarHBondContact O-CD 3.41Å; P192-K230 PolarHBondContact O-NZ 3.05Å; E212-K230 VanDerWaalsContact OE1-CE 3.27Å; E212-K230 WeakPolarHBondContact OE1-CE 3.37Å; E212-K230 IonicContact OE1-NZ 2.73Å; E212-K230 PolarHBondContact OE1-NZ 3.26Å; E212-K230 IonicContact OE2-NZ 3.69Å; E212-K230 PolarHBondContact OE2-NZ 3.49Å; K230-A503 HydrophobicContact CB-CB 4.2Å; K230-A503 WeakPolarHBondContact O-CB 3.47Å
231T87.2Confident80.4Confident15 Ų1550 Ų509%0.09228%0.283CS..PPolyproline II helixtrans-82.4173.4174.457.10000110.1E190 N191 G229 S233 A503E190-T231 WeakPolarHBondContact OE2-CB 3.29Å; E190-T231 PolarHBondContact OE2-OG1 3.34Å; N191-T231 HydrophobicContact CB-CG2 4.34Å; N191-T231 PolarHBondContact N-OG1 3.45Å; N191-T231 PolarHBondContact O-N 3.22Å; N191-T231 PolarHBondContact O-OG1 3.29Å; G229-T231 PolarHBondContact O-N 3.09Å; T231-S233 PolarHBondContact O-N 3.41Å; T231-S233 VanDerWaalsContact O-N 3.08Å; T231-S233 PolarHBondContact OG1-OG 2.57Å; T231-A503 WeakPolarHBondContact O-CB 3.2Å
232Q85.2Confident81.9Confident57 Ų5745.2 Ų45.227%0.26626%0.258SS..SBendtrans-7621.5174.4-64.1-167.70.900113.4W505 L522Q232-W505 WeakPolarHBondContact O-CZ3 3.22Å; Q232-L522 VanDerWaalsContact NE2-CD2 3.25Å
233S91.8Very high83.8Confident3 Ų342.1 Ų42.12%0.02124%0.241CC..  trans-95.5157.8173.958.10000112.3E190 P192 G193 T231 R531E190-S233 WeakPolarHBondContact OE2-CB 3.22Å; E190-S233 PolarHBondContact OE2-OG 3.24Å; P192-S233 WeakPolarHBondContact CA-O 3.05Å; P192-S233 WeakPolarHBondContact CA-OG 3.25Å; P192-S233 WeakPolarHBondContact CB-OG 3.47Å; G193-S233 PolarHBondContact N-O 2.86Å; T231-S233 PolarHBondContact O-N 3.41Å; T231-S233 VanDerWaalsContact O-N 3.08Å; T231-S233 PolarHBondContact OG1-OG 2.57Å; S233-R531 CarbonylContact C-O 3.59Å; S233-R531 WeakPolarHBondContact CA-O 3.36Å; S233-R531 WeakPolarHBondContact CB-O 3.35Å
234Q94.4Very high85.8Confident2 Ų234.4 Ų34.41%0.00921%0.206CC..EExtended strand (participates in β ladder)trans-122.9145.9171.9-80.8-170.337.500110.8G193 R195 Y497 W505 R531 L532 I533G193-Q234 WeakPolarHBondContact O-CA 3.36Å; R195-Q234 VanDerWaalsContact CD-OE1 3.23Å; Q234-Y497 PolarHBondContact NE2-OH 3.45Å; Q234-W505 HydrophobicContact CB-CE3 4.19Å; Q234-W505 HydrophobicContact CB-CH2 4.2Å; Q234-W505 HydrophobicContact CB-CZ3 3.94Å; Q234-W505 HydrophobicContact CG-CD2 3.84Å; Q234-W505 HydrophobicContact CG-CE3 3.57Å; Q234-W505 HydrophobicContact CG-CG 4.37Å; Q234-W505 HydrophobicContact CG-CH2 4.37Å; Q234-W505 HydrophobicContact CG-CZ3 3.86Å; Q234-W505 VanDerWaalsContact NE2-CB 3.27Å; Q234-R531 PolarHBondContact N-O 3.48Å; Q234-L532 HydrophobicContact CB-CD1 3.92Å; Q234-I533 PolarHBondContact O-N 3.41Å
235L97.4Very high87.8Confident0 Ų029 Ų290%018%0.178CC..EExtended strand (participates in β ladder)trans-115.6120.5167.7171.362.4000108.5I181 P192 G193 V194 R195 V211 I237 I533 F535I181-L235 HydrophobicContact CG2-CD2 3.66Å; P192-L235 HydrophobicContact CB-CB 3.95Å; P192-L235 HydrophobicContact CG-CB 3.81Å; G193-L235 PolarHBondContact O-N 3.5Å; V194-L235 HydrophobicContact CG1-CD2 4.4Å; V194-L235 HydrophobicContact CG2-CB 4.43Å; V194-L235 HydrophobicContact CG2-CD2 4.23Å; R195-L235 PolarHBondContact N-O 3.02Å; V211-L235 HydrophobicContact CG1-CD2 3.71Å; L235-I237 HydrophobicContact CD1-CG1 4.4Å; L235-I237 HydrophobicContact CD2-CD1 4.21Å; L235-I237 HydrophobicContact CD2-CG1 4.33Å; L235-I237 HydrophobicContact CG-CG1 4.08Å; L235-I533 CarbonylContact C-O 3.59Å; L235-I533 VanDerWaalsContact CA-O 3.26Å; L235-I533 WeakPolarHBondContact CA-O 3.47Å; L235-I533 HydrophobicContact CD1-CB 3.96Å; L235-I533 HydrophobicContact CD1-CG2 3.67Å; L235-F535 HydrophobicContact CD1-CB 4.27Å
236L98.2Very high90Very high0 Ų026 Ų260%015%0.146CC..EExtended strand (participates in β ladder)trans-105.3125.6172.7-52.2-172.1000110.4R195 I481 A485 L490 W495 L532 I533 I534 F535R195-L236 HydrophobicContact CB-CD2 3.64Å; R195-L236 HydrophobicContact CG-CD2 4.13Å; R195-L236 WeakPolarHBondContact O-CA 3.25Å; L236-I481 HydrophobicContact CD1-CG2 4.07Å; L236-A485 HydrophobicContact CD1-CB 3.77Å; L236-L490 HydrophobicContact CD1-CD1 3.8Å; L236-L490 HydrophobicContact CD2-CD1 4.37Å; L236-W495 HydrophobicContact CB-CZ3 4.48Å; L236-L532 HydrophobicContact CD1-CD1 4.08Å; L236-L532 HydrophobicContact CG-CD1 3.94Å; L236-I533 PolarHBondContact N-O 3.2Å; L236-I534 HydrophobicContact CB-CD1 3.72Å; L236-I534 HydrophobicContact CD1-CD1 3.62Å; L236-I534 HydrophobicContact CG-CD1 3.77Å; L236-F535 PolarHBondContact O-N 3.25Å
237I98.8Very high92.1Very high0 Ų021.2 Ų21.20%012%0.121CC..EExtended strand (participates in β ladder)trans-109.1130.5176.1-54.3-168000110.5V194 R195 Y196 K197 A204 L207 A208 V211 L235 F535 I537V194-I237 HydrophobicContact CG1-CD1 4.46Å; R195-I237 PolarHBondContact O-N 3.05Å; Y196-I237 CarbonylContact C-O 3.54Å; Y196-I237 VanDerWaalsContact CA-O 3.23Å; Y196-I237 WeakPolarHBondContact CA-O 3.47Å; K197-I237 PolarHBondContact N-O 3.07Å; A204-I237 HydrophobicContact CB-CG2 4.12Å; L207-I237 HydrophobicContact CB-CG2 4.36Å; L207-I237 HydrophobicContact CD2-CD1 4.39Å; L207-I237 HydrophobicContact CD2-CG2 3.94Å; L207-I237 HydrophobicContact CG-CD1 4.09Å; L207-I237 HydrophobicContact CG-CG2 4.35Å; A208-I237 HydrophobicContact CB-CB 4.48Å; A208-I237 HydrophobicContact CB-CD1 3.96Å; A208-I237 HydrophobicContact CB-CG1 4.48Å; V211-I237 HydrophobicContact CB-CD1 4.47Å; V211-I237 HydrophobicContact CG2-CD1 4.11Å; L235-I237 HydrophobicContact CD1-CG1 4.4Å; L235-I237 HydrophobicContact CD2-CD1 4.21Å; L235-I237 HydrophobicContact CD2-CG1 4.33Å; L235-I237 HydrophobicContact CG-CG1 4.08Å; I237-F535 WeakPolarHBondContact CA-O 3.33Å; I237-F535 HydrophobicContact CG1-CB 4.44Å; I237-F535 HydrophobicContact CG2-CD1 4.35Å; I237-I537 HydrophobicContact CG2-CD1 4Å; I237-I537 HydrophobicContact CG2-CG1 4.17Å
238I98.6Very high93.7Very high0 Ų014.7 Ų14.70%09%0.088CC..EExtended strand (participates in β ladder)trans-137.3139.8-171.3-42.9173.4000110.3K197 F242 I481 W495 I534 F535 V536 I537K197-I238 HydrophobicContact CB-CG2 4.15Å; I238-F242 HydrophobicContact CG2-CB 3.72Å; I238-F242 HydrophobicContact CG2-CD1 3.61Å; I238-F242 HydrophobicContact CG2-CD2 4.32Å; I238-F242 HydrophobicContact CG2-CE1 4.29Å; I238-F242 HydrophobicContact CG2-CG 3.6Å; I238-I481 HydrophobicContact CD1-CD1 4.42Å; I238-I481 HydrophobicContact CD1-CG2 4.35Å; I238-W495 HydrophobicContact CD1-CH2 3.65Å; I238-W495 HydrophobicContact CD1-CZ3 3.98Å; I238-W495 HydrophobicContact CG1-CH2 3.74Å; I238-W495 HydrophobicContact CG1-CZ3 3.71Å; I238-W495 HydrophobicContact CG2-CH2 4.34Å; I238-I534 HydrophobicContact CD1-CG2 4.26Å; I238-F535 PolarHBondContact N-O 2.79Å; I238-V536 CarbonylContact O-C 3.56Å; I238-V536 WeakPolarHBondContact O-CA 3.32Å; I238-I537 PolarHBondContact O-N 3.09Å
239D98.5Very high94.9Very high11 Ų1113.2 Ų13.26%0.0598%0.082CC..EExtended strand (participates in β ladder)trans-75.6142.5168.3-89.1-77000112Y160 N203 A204 G241 F242Y160-D239 WeakPolarHBondContact CE1-OD1 3.44Å; Y160-D239 WeakPolarHBondContact OH-CA 3.42Å; Y160-D239 PolarHBondContact OH-OD1 3.48Å; N203-D239 VanDerWaalsContact CB-OD1 3.26Å; N203-D239 WeakPolarHBondContact CB-OD1 3.47Å; N203-D239 PolarHBondContact ND2-OD1 3.19Å; A204-D239 WeakPolarHBondContact CB-OD2 3.35Å; A204-D239 PolarHBondContact N-OD2 3.41Å; D239-G241 PolarHBondContact O-N 3Å; D239-G241 VanDerWaalsContact O-N 3.08Å; D239-F242 VanDerWaalsContact O-CD1 3.22Å; D239-F242 WeakPolarHBondContact O-CD1 3.22Å; D239-F242 PolarHBondContact O-N 2.78Å
240R97.4Very high95.7Very high0 Ų011.1 Ų11.10%06%0.059CC..G310 helixtrans-50.5-37.1-177.9-169.953.6-90.4173.8-6.3114.7F156 Y160 F242 D243 L445 I537 G539 E544F156-R240 HydrophobicContact CE2-CG 4.3Å; Y160-R240 HydrophobicContact CE2-CB 4.18Å; Y160-R240 PolarHBondContact OH-N 2.91Å; R240-F242 PolarHBondContact O-N 3.18Å; R240-D243 PolarHBondContact NH2-O 3.06Å; R240-L445 HydrophobicContact CB-CD2 4.22Å; R240-L445 HydrophobicContact CG-CD2 4.16Å; R240-I537 VanDerWaalsContact CB-O 3.28Å; R240-I537 WeakPolarHBondContact CB-O 3.14Å; R240-I537 PolarHBondContact N-O 2.6Å; R240-I537 VanDerWaalsContact N-O 3.12Å; R240-G539 WeakPolarHBondContact CD-O 3.49Å; R240-G539 PolarHBondContact NH1-O 3.32Å; R240-E544 IonicContact CZ-OE1 2.74Å; R240-E544 VanDerWaalsContact CZ-OE1 3.3Å; R240-E544 IonicContact CZ-OE2 2.7Å; R240-E544 VanDerWaalsContact NH1-CD 3.3Å; R240-E544 IonicContact NH1-OE1 2.65Å; R240-E544 PolarHBondContact NH1-OE1 3.21Å; R240-E544 VanDerWaalsContact NH1-OE1 3.12Å; R240-E544 IonicContact NH1-OE2 2.9Å; R240-E544 PolarHBondContact NH1-OE2 2.85Å; R240-E544 IonicContact NH2-OE1 3.17Å; R240-E544 PolarHBondContact NH2-OE1 2.77Å; R240-E544 IonicContact NH2-OE2 2.92Å
241G97Very high96.2Very high11 Ų1110 Ų1011%0.1135%0.054CC..G310 helixtrans-64.6-1.8-176.100000115.8D239 D243 V447D239-G241 PolarHBondContact O-N 3Å; D239-G241 VanDerWaalsContact O-N 3.08Å; G241-D243 VanDerWaalsContact C-N 3.31Å; G241-D243 PolarHBondContact O-N 3.38Å; G241-V447 WeakPolarHBondContact O-CG2 3.32Å
242F96.5Very high96.7Very high34 Ų349.5 Ų9.515%0.1495%0.051CC..G310 helixtrans-65.5-31.317984-80.5000113.9I238 D239 R240 F477 I478 I481 V536 E544I238-F242 HydrophobicContact CG2-CB 3.72Å; I238-F242 HydrophobicContact CG2-CD1 3.61Å; I238-F242 HydrophobicContact CG2-CD2 4.32Å; I238-F242 HydrophobicContact CG2-CE1 4.29Å; I238-F242 HydrophobicContact CG2-CG 3.6Å; D239-F242 VanDerWaalsContact O-CD1 3.22Å; D239-F242 WeakPolarHBondContact O-CD1 3.22Å; D239-F242 PolarHBondContact O-N 2.78Å; R240-F242 PolarHBondContact O-N 3.18Å; F242-F477 HydrophobicContact CD2-CB 4.36Å; F242-F477 HydrophobicContact CE2-CB 4.21Å; F242-I478 HydrophobicContact CE2-CB 3.88Å; F242-I478 HydrophobicContact CE2-CG1 4.11Å; F242-I478 HydrophobicContact CZ-CB 3.88Å; F242-I478 HydrophobicContact CZ-CD1 3.96Å; F242-I478 HydrophobicContact CZ-CG1 3.93Å; F242-I481 HydrophobicContact CD2-CD1 3.74Å; F242-I481 HydrophobicContact CE2-CD1 3.88Å; F242-V536 HydrophobicContact CE1-CG1 4.02Å; F242-V536 HydrophobicContact CE1-CG2 4.24Å; F242-E544 VanDerWaalsContact CZ-OE1 3.25Å; F242-E544 WeakPolarHBondContact CZ-OE1 3.42Å
243D97.2Very high97.4Very high0 Ų07.3 Ų7.30%04%0.042CC..  trans-138.282.4179.7-172.6-6.1000110R240 G241 V245 S246 P476 F477R240-D243 PolarHBondContact NH2-O 3.06Å; G241-D243 VanDerWaalsContact C-N 3.31Å; G241-D243 PolarHBondContact O-N 3.38Å; D243-V245 VanDerWaalsContact C-N 3.31Å; D243-V245 PolarHBondContact OD1-N 3.5Å; D243-S246 VanDerWaalsContact CG-CB 3.5Å; D243-S246 WeakPolarHBondContact OD1-CB 3.43Å; D243-S246 PolarHBondContact OD1-N 3.02Å; D243-S246 PolarHBondContact OD1-OG 2.73Å; D243-S246 VanDerWaalsContact OD2-CB 3.25Å; D243-S246 WeakPolarHBondContact OD2-CB 3.34Å; D243-S246 PolarHBondContact OD2-OG 3.2Å; D243-P476 WeakPolarHBondContact OD2-CA 3.45Å; D243-F477 HydrophobicContact CB-CB 4.06Å; D243-F477 HydrophobicContact CB-CD2 4.11Å; D243-F477 PolarHBondContact OD2-N 3.12Å
244P97.8Very high97.7Very high17 Ų177.1 Ų7.111%0.114%0.041CC..SBendtrans-77.5-17.1178.832.4-36.6000113T247 F413 W442 V447P244-T247 VanDerWaalsContact C-OG1 3.29Å; P244-T247 PolarHBondContact O-OG1 3.49Å; P244-F413 HydrophobicContact CB-CD1 4.23Å; P244-F413 HydrophobicContact CB-CD2 3.94Å; P244-F413 HydrophobicContact CB-CE1 3.98Å; P244-F413 HydrophobicContact CB-CE2 3.66Å; P244-F413 HydrophobicContact CB-CG 4.22Å; P244-F413 HydrophobicContact CB-CZ 3.68Å; P244-F413 HydrophobicContact CG-CD1 4.18Å; P244-F413 HydrophobicContact CG-CD2 4.19Å; P244-F413 HydrophobicContact CG-CE1 4.39Å; P244-F413 HydrophobicContact CG-CE2 4.39Å; P244-F413 HydrophobicContact CG-CG 4.09Å; P244-F413 HydrophobicContact CG-CZ 4.49Å; P244-F413 VanDerWaalsContact O-CE2 3.22Å; P244-F413 WeakPolarHBondContact O-CE2 3.01Å; P244-W442 HydrophobicContact CB-CE3 3.9Å; P244-W442 HydrophobicContact CB-CH2 4.11Å; P244-W442 HydrophobicContact CB-CZ3 3.49Å; P244-W442 VanDerWaalsContact CB-CZ3 3.49Å; P244-V447 HydrophobicContact CB-CG1 4.05Å; P244-V447 HydrophobicContact CB-CG2 4.01Å; P244-V447 HydrophobicContact CG-CG1 3.87Å; P244-V447 HydrophobicContact CG-CG2 4.11Å
245V97.9Very high97.9Very high9 Ų97.1 Ų7.16%0.0554%0.041CC..SBendtrans-74.5-50.3-178.8173.40000110.1D243 T247 V248 L249 A373 L410 F413 W474D243-V245 VanDerWaalsContact C-N 3.31Å; D243-V245 PolarHBondContact OD1-N 3.5Å; V245-T247 PolarHBondContact O-N 2.88Å; V245-V248 PolarHBondContact O-N 3.08Å; V245-V248 VanDerWaalsContact O-N 3.12Å; V245-L249 HydrophobicContact CG1-CD1 4.35Å; V245-L249 WeakPolarHBondContact O-CB 3.26Å; V245-L249 PolarHBondContact O-N 3Å; V245-A373 HydrophobicContact CG1-CB 3.7Å; V245-L410 HydrophobicContact CB-CD2 4.41Å; V245-L410 HydrophobicContact CG1-CD2 3.74Å; V245-F413 HydrophobicContact CG2-CB 3.87Å; V245-F413 HydrophobicContact CG2-CD2 4.15Å; V245-F413 HydrophobicContact CG2-CG 4.43Å; V245-W474 HydrophobicContact CB-CH2 3.78Å; V245-W474 HydrophobicContact CB-CZ2 3.46Å; V245-W474 VanDerWaalsContact CB-CZ2 3.46Å; V245-W474 HydrophobicContact CG1-CD2 3.72Å; V245-W474 VanDerWaalsContact CG1-CE2 3.42Å; V245-W474 HydrophobicContact CG1-CE3 3.97Å; V245-W474 HydrophobicContact CG1-CG 4.42Å; V245-W474 HydrophobicContact CG1-CH2 3.68Å; V245-W474 HydrophobicContact CG1-CZ2 3.42Å; V245-W474 VanDerWaalsContact CG1-CZ2 3.42Å; V245-W474 HydrophobicContact CG1-CZ3 3.94Å; V245-W474 HydrophobicContact CG2-CH2 4.01Å; V245-W474 HydrophobicContact CG2-CZ2 4.18Å
246S98.1Very high97.9Very high8 Ų87.6 Ų7.66%0.0564%0.044CC..THydrogen-bonded Turntrans-59.8-19.3-179.1-65.10000114.2D243 W474 P476D243-S246 VanDerWaalsContact CG-CB 3.5Å; D243-S246 WeakPolarHBondContact OD1-CB 3.43Å; D243-S246 PolarHBondContact OD1-N 3.02Å; D243-S246 PolarHBondContact OD1-OG 2.73Å; D243-S246 VanDerWaalsContact OD2-CB 3.25Å; D243-S246 WeakPolarHBondContact OD2-CB 3.34Å; D243-S246 PolarHBondContact OD2-OG 3.2Å; S246-W474 PolarHBondContact OG-NE1 3.4Å; S246-P476 VanDerWaalsContact OG-CA 3.27Å; S246-P476 WeakPolarHBondContact OG-CA 3.31Å; S246-P476 WeakPolarHBondContact OG-CB 3.34Å
247T98.2Very high97.9Very high2 Ų27.7 Ų7.71%0.0125%0.045CC..THydrogen-bonded Turntrans-85.3-16.3-178.752.90000114.9P244 V245 W442 T541 L573P244-T247 VanDerWaalsContact C-OG1 3.29Å; P244-T247 PolarHBondContact O-OG1 3.49Å; V245-T247 PolarHBondContact O-N 2.88Å; T247-W442 VanDerWaalsContact OG1-CH2 3.22Å; T247-W442 WeakPolarHBondContact OG1-CH2 3.48Å; T247-T541 HydrophobicContact CG2-CG2 3.78Å; T247-L573 VanDerWaalsContact CB-CD2 3.4Å; T247-L573 HydrophobicContact CG2-CD2 3.93Å
248V98.1Very high97.9Very high0 Ų07.7 Ų7.70%05%0.045CC..THydrogen-bonded Turntrans-125.5-13.3-177.7-59.50000113.5V245 R406 L409 L410 F413 W442 L574V245-V248 PolarHBondContact O-N 3.08Å; V245-V248 VanDerWaalsContact O-N 3.12Å; V248-R406 HydrophobicContact CB-CB 4.44Å; V248-R406 HydrophobicContact CB-CG 4.26Å; V248-R406 VanDerWaalsContact O-CZ 3.29Å; V248-R406 PolarHBondContact O-NE 3.06Å; V248-R406 PolarHBondContact O-NH2 3.47Å; V248-L409 HydrophobicContact CG1-CD1 4.05Å; V248-L409 HydrophobicContact CG2-CB 4.36Å; V248-L410 HydrophobicContact CG2-CD2 3.8Å; V248-L410 HydrophobicContact CG2-CG 3.89Å; V248-F413 HydrophobicContact CG2-CD2 4.37Å; V248-F413 HydrophobicContact CG2-CE2 3.9Å; V248-W442 HydrophobicContact CG1-CZ2 3.91Å; V248-L574 HydrophobicContact CG1-CD2 4.36Å
249L97.9Very high97.9Very high14 Ų148.5 Ų8.57%0.0735%0.048CC..SBendtrans-71137.3177.2-173.8107.8000111.4V245 E251 E369 A373 L410 W474V245-L249 HydrophobicContact CG1-CD1 4.35Å; V245-L249 WeakPolarHBondContact O-CB 3.26Å; V245-L249 PolarHBondContact O-N 3Å; L249-E251 PolarHBondContact O-N 3.03Å; L249-E369 HydrophobicContact CD1-CB 4.14Å; L249-A373 HydrophobicContact CD1-CB 3.71Å; L249-L410 HydrophobicContact CB-CD2 4.35Å; L249-L410 HydrophobicContact CD1-CD1 4.35Å; L249-L410 HydrophobicContact CD1-CD2 4.16Å; L249-W474 HydrophobicContact CD1-CB 4.39Å; L249-W474 HydrophobicContact CD2-CB 3.66Å; L249-W474 HydrophobicContact CD2-CG 3.85Å
250H98Very high97.8Very high4 Ų49.6 Ų9.62%0.0195%0.054CC..  trans-67.4130.1166.1-72.792.2000110.4D260 I362 E369 D403 R406H250-D260 IonicContact CD2-OD2 2.75Å; H250-D260 PolarHBondContact CD2-OD2 3.49Å; H250-D260 IonicContact CG-OD2 2.78Å; H250-D260 IonicContact NE2-OD2 2.85Å; H250-I362 HydrophobicContact CB-CG2 4.37Å; H250-E369 WeakPolarHBondContact CB-OE2 3.23Å; H250-E369 IonicContact CE1-OE1 3.29Å; H250-E369 IonicContact CG-OE1 2.71Å; H250-E369 IonicContact CG-OE2 3.16Å; H250-E369 PolarHBondContact N-OE2 3.25Å; H250-E369 VanDerWaalsContact ND1-CD 3.27Å; H250-E369 IonicContact ND1-OE1 4Å; H250-E369 PolarHBondContact ND1-OE1 2.97Å; H250-E369 IonicContact ND1-OE2 2.68Å; H250-E369 PolarHBondContact ND1-OE2 3.46Å; H250-D403 IonicContact CE1-OD1 2.91Å; H250-D403 IonicContact NE2-OD1 3.56Å; H250-R406 PolarHBondContact CD2-NH2 3.17Å; H250-R406 PolarHBondContact CE1-NH1 3.16Å; H250-R406 VanDerWaalsContact CE1-NH1 3.29Å; H250-R406 PolarHBondContact ND1-NH2 2.81Å; H250-R406 PolarHBondContact NE2-NH1 2.96Å
251E96.7Very high97.8Very high23 Ų2310.8 Ų10.811%0.1076%0.06CC..  trans-115.6135175.9-171.5-171.1176.900110.2L249 T253 A256 M257 S543 R546L249-E251 PolarHBondContact O-N 3.03Å; E251-T253 HydrophobicContact CG-CG2 4.18Å; E251-T253 VanDerWaalsContact OE1-CG2 3.31Å; E251-T253 WeakPolarHBondContact OE1-CG2 3.39Å; E251-T253 PolarHBondContact OE1-OG1 3.38Å; E251-A256 HydrophobicContact CB-CB 3.91Å; E251-A256 HydrophobicContact CG-CB 4.11Å; E251-A256 WeakPolarHBondContact OE2-CB 3.44Å; E251-M257 WeakPolarHBondContact O-CA 3.45Å; E251-M257 WeakPolarHBondContact O-CB 3.5Å; E251-M257 PolarHBondContact O-N 3.17Å; E251-S543 WeakPolarHBondContact OE2-CA 3.28Å; E251-S543 WeakPolarHBondContact OE2-CB 3.37Å; E251-S543 PolarHBondContact OE2-N 2.87Å; E251-R546 IonicContact OE1-CZ 3.85Å; E251-R546 IonicContact OE1-NE 3.9Å; E251-R546 PolarHBondContact OE1-NE 3.03Å; E251-R546 IonicContact OE1-NH2 2.86Å; E251-R546 PolarHBondContact OE1-NH2 2.81Å
252L97.8Very high97.8Very high5 Ų511.1 Ų11.13%0.0266%0.059CC..  trans-99.219.9-176.2-51.6-178.3000113.2M257 H296 I297 F358 L471 S472L252-M257 HydrophobicContact CD2-CE 4.17Å; L252-M257 HydrophobicContact CD2-SD 4.28Å; L252-H296 WeakPolarHBondContact CB-NE2 3.23Å; L252-H296 WeakPolarHBondContact O-CA 3.17Å; L252-I297 HydrophobicContact CB-CG2 4.19Å; L252-I297 PolarHBondContact O-N 2.96Å; L252-F358 HydrophobicContact CD1-CE2 3.87Å; L252-F358 HydrophobicContact CD1-CZ 4.18Å; L252-F358 HydrophobicContact CD2-CD2 3.79Å; L252-F358 HydrophobicContact CD2-CE2 3.69Å; L252-F358 HydrophobicContact CG-CE2 4.46Å; L252-L471 HydrophobicContact CD1-CB 3.86Å; L252-S472 WeakPolarHBondContact CB-OG 3.21Å; L252-S472 WeakPolarHBondContact CG-OG 3.46Å
253T98.2Very high97.7Very high10 Ų1015 Ų156%0.0619%0.087CC..BIsolated β-bridgetrans-81.1143.5165650000109.5E251 Q255 A256 M257 R295E251-T253 HydrophobicContact CG-CG2 4.18Å; E251-T253 VanDerWaalsContact OE1-CG2 3.31Å; E251-T253 WeakPolarHBondContact OE1-CG2 3.39Å; E251-T253 PolarHBondContact OE1-OG1 3.38Å; T253-Q255 PolarHBondContact O-N 2.87Å; T253-A256 PolarHBondContact O-N 3.18Å; T253-M257 WeakPolarHBondContact O-CB 3.29Å; T253-M257 PolarHBondContact O-N 3.05Å; T253-R295 WeakPolarHBondContact CA-O 3.35Å
254F98.4Very high97.7Very high0 Ų015.8 Ų15.80%09%0.092CC..Hα-helixtrans-59.4-43.2-159.8-175-145.6000114.2A258 W289 V292 R293 R295 I297 V300 H347 L350 A351F254-A258 WeakPolarHBondContact O-CB 3.41Å; F254-A258 PolarHBondContact O-N 3.32Å; F254-W289 HydrophobicContact CD1-CE3 4.27Å; F254-W289 AromaticContact CD1-CZ3 3.77Å; F254-W289 HydrophobicContact CD1-CZ3 3.77Å; F254-W289 HydrophobicContact CE1-CE3 4.05Å; F254-W289 AromaticContact CE1-CZ3 3.68Å; F254-W289 HydrophobicContact CE1-CZ3 3.68Å; F254-W289 HydrophobicContact CG-CZ3 4.5Å; F254-W289 HydrophobicContact CZ-CZ3 4.34Å; F254-V292 HydrophobicContact CD1-CB 4.33Å; F254-V292 HydrophobicContact CD1-CG2 3.65Å; F254-V292 HydrophobicContact CE1-CG2 3.74Å; F254-R293 PolarHBondContact N-O 2.98Å; F254-R295 PolarHBondContact N-O 3.35Å; F254-I297 HydrophobicContact CD2-CD1 3.85Å; F254-I297 HydrophobicContact CE2-CD1 4.25Å; F254-V300 HydrophobicContact CB-CG2 3.9Å; F254-V300 HydrophobicContact CD1-CG1 3.9Å; F254-V300 HydrophobicContact CD1-CG2 4.29Å; F254-V300 HydrophobicContact CD2-CG1 4.43Å; F254-V300 HydrophobicContact CE1-CG1 4Å; F254-V300 HydrophobicContact CG-CG1 4.12Å; F254-V300 HydrophobicContact CG-CG2 4.19Å; F254-V300 HydrophobicContact CZ-CG1 4.3Å; F254-H347 HydrophobicContact CE1-CB 4.45Å; F254-L350 HydrophobicContact CE1-CD2 4.16Å; F254-L350 HydrophobicContact CE2-CB 4.26Å; F254-L350 HydrophobicContact CE2-CD2 3.97Å; F254-L350 HydrophobicContact CE2-CG 3.79Å; F254-L350 HydrophobicContact CZ-CB 3.93Å; F254-L350 HydrophobicContact CZ-CD2 3.55Å; F254-L350 HydrophobicContact CZ-CG 3.72Å; F254-A351 HydrophobicContact CE2-CB 3.92Å; F254-A351 HydrophobicContact CZ-CB 4.18Å
255Q98.4Very high97.4Very high2 Ų221.7 Ų21.71%0.00912%0.118CC..Hα-helixtrans-66-54.4176.9-171.717322.300112.1E144 T253 M257 A258 Y259 W289 R293 H294 Y542E144-Q255 PolarHBondContact OE1-NE2 2.93Å; T253-Q255 PolarHBondContact O-N 2.87Å; Q255-M257 VanDerWaalsContact C-N 3.28Å; Q255-M257 PolarHBondContact O-N 3.05Å; Q255-A258 PolarHBondContact O-N 2.99Å; Q255-Y259 HydrophobicContact CG-CD2 4.06Å; Q255-Y259 HydrophobicContact CG-CE2 4.09Å; Q255-Y259 WeakPolarHBondContact O-CD2 3.15Å; Q255-Y259 PolarHBondContact O-N 2.95Å; Q255-W289 HydrophobicContact CB-CH2 4.11Å; Q255-W289 HydrophobicContact CB-CZ2 4.17Å; Q255-W289 HydrophobicContact CG-CH2 4.16Å; Q255-W289 HydrophobicContact CG-CZ2 3.83Å; Q255-R293 HydrophobicContact CB-CB 4.04Å; Q255-R293 VanDerWaalsContact CB-O 3.24Å; Q255-R293 WeakPolarHBondContact CB-O 3.45Å; Q255-R293 PolarHBondContact N-O 3.02Å; Q255-H294 PolarHBondContact OE1-CE1 3.39Å; Q255-H294 PolarHBondContact OE1-ND1 3.31Å; Q255-Y542 HydrophobicContact CG-CD1 3.56Å; Q255-Y542 HydrophobicContact CG-CE1 4.07Å; Q255-Y542 HydrophobicContact CG-CG 4.14Å
256A98.2Very high97.1Very high10 Ų1030.5 Ų30.58%0.08316%0.155CC..Hα-helixtrans-59.5-43.9-177.900000111.2E251 T253 A258 Y259 D260E251-A256 HydrophobicContact CB-CB 3.91Å; E251-A256 HydrophobicContact CG-CB 4.11Å; E251-A256 WeakPolarHBondContact OE2-CB 3.44Å; T253-A256 PolarHBondContact O-N 3.18Å; A256-A258 PolarHBondContact O-N 2.92Å; A256-Y259 PolarHBondContact O-N 3.15Å; A256-D260 VanDerWaalsContact O-CB 3.3Å; A256-D260 WeakPolarHBondContact O-CB 3.42Å; A256-D260 PolarHBondContact O-N 2.8Å
257M98.2Very high96.9Very high1 Ų132.2 Ų32.21%0.00516%0.164CC..Hα-helixtrans-60.6-44.8176.2-170179.8-173.300112.2E251 L252 T253 Q255 D260 L261 I297 C354 M355 F358E251-M257 WeakPolarHBondContact O-CA 3.45Å; E251-M257 WeakPolarHBondContact O-CB 3.5Å; E251-M257 PolarHBondContact O-N 3.17Å; L252-M257 HydrophobicContact CD2-CE 4.17Å; L252-M257 HydrophobicContact CD2-SD 4.28Å; T253-M257 WeakPolarHBondContact O-CB 3.29Å; T253-M257 PolarHBondContact O-N 3.05Å; Q255-M257 VanDerWaalsContact C-N 3.28Å; Q255-M257 PolarHBondContact O-N 3.05Å; M257-D260 PolarHBondContact O-N 3.44Å; M257-L261 HydrophobicContact CE-CD1 3.69Å; M257-L261 HydrophobicContact CG-CD1 3.66Å; M257-L261 HydrophobicContact CG-CG 4.3Å; M257-L261 WeakPolarHBondContact O-CB 3.29Å; M257-L261 WeakPolarHBondContact O-CG 3.39Å; M257-L261 PolarHBondContact O-N 3.4Å; M257-I297 HydrophobicContact SD-CB 3.87Å; M257-I297 HydrophobicContact SD-CD1 4.46Å; M257-I297 HydrophobicContact SD-CG1 3.93Å; M257-I297 HydrophobicContact SD-CG2 3.99Å; M257-C354 HydrophobicContact CE-CB 3.92Å; M257-C354 WeakPolarHBondContact CE-O 3.1Å; M257-C354 HydrophobicContact CG-CB 4.21Å; M257-C354 HydrophobicContact SD-CB 3.94Å; M257-M355 HydrophobicContact CE-SD 4.4Å; M257-F358 HydrophobicContact CE-CB 3.48Å; M257-F358 VanDerWaalsContact CE-CB 3.48Å; M257-F358 HydrophobicContact CE-CD2 4.1Å; M257-F358 HydrophobicContact CE-CG 3.92Å
258A98.5Very high96.8Very high0 Ų033.7 Ų33.70%017%0.173CC..Hα-helixtrans-63.5-47.4-179.400000112.1F254 Q255 A256 D260 L262 I264 L350 C354F254-A258 WeakPolarHBondContact O-CB 3.41Å; F254-A258 PolarHBondContact O-N 3.32Å; Q255-A258 PolarHBondContact O-N 2.99Å; A256-A258 PolarHBondContact O-N 2.92Å; A258-D260 VanDerWaalsContact C-N 3.32Å; A258-D260 PolarHBondContact O-N 3.17Å; A258-L262 VanDerWaalsContact O-CB 3.26Å; A258-L262 WeakPolarHBondContact O-CB 3.41Å; A258-L262 PolarHBondContact O-N 3.09Å; A258-I264 HydrophobicContact CB-CD1 3.93Å; A258-L350 HydrophobicContact CB-CD1 4.11Å; A258-L350 HydrophobicContact CB-CD2 4.42Å; A258-L350 HydrophobicContact CB-CG 4.37Å; A258-C354 VanDerWaalsContact CA-SG 3.59Å
259Y98Very high96.8Very high18 Ų1833.9 Ų33.97%0.07117%0.174CC..Hα-helixtrans-75.3-19-178.9-79-95.8000113.9Q255 A256 I264 D267 L282 W289 Y542 T569Q255-Y259 HydrophobicContact CG-CD2 4.06Å; Q255-Y259 HydrophobicContact CG-CE2 4.09Å; Q255-Y259 WeakPolarHBondContact O-CD2 3.15Å; Q255-Y259 PolarHBondContact O-N 2.95Å; A256-Y259 PolarHBondContact O-N 3.15Å; Y259-I264 HydrophobicContact CD1-CB 4.11Å; Y259-I264 HydrophobicContact CD1-CG2 3.94Å; Y259-I264 HydrophobicContact CD2-CD1 4.25Å; Y259-I264 HydrophobicContact CE1-CB 4.22Å; Y259-I264 HydrophobicContact CE1-CG2 3.53Å; Y259-I264 HydrophobicContact CE2-CD1 4.42Å; Y259-I264 HydrophobicContact CG-CD1 4.32Å; Y259-D267 WeakPolarHBondContact CE1-OD1 3.37Å; Y259-D267 PolarHBondContact OH-OD1 3.49Å; Y259-L282 HydrophobicContact CE2-CD1 4.14Å; Y259-W289 HydrophobicContact CE2-CZ2 4.31Å; Y259-Y542 HydrophobicContact CD1-CE1 4.5Å; Y259-Y542 AromaticContact CD1-CE2 3.77Å; Y259-Y542 HydrophobicContact CD1-CE2 3.77Å; Y259-Y542 AromaticContact CD1-CZ 3.53Å; Y259-Y542 WeakPolarHBondContact CD1-OH 3.33Å; Y259-Y542 HydrophobicContact CD2-CE1 4.07Å; Y259-Y542 HydrophobicContact CD2-CE2 4.04Å; Y259-Y542 AromaticContact CD2-CZ 3.77Å; Y259-Y542 AromaticContact CE1-CZ 3.83Å; Y259-Y542 WeakPolarHBondContact CE1-OH 3.39Å; Y259-Y542 HydrophobicContact CE2-CE1 4.16Å; Y259-Y542 HydrophobicContact CG-CD2 4.2Å; Y259-Y542 HydrophobicContact CG-CE1 4.23Å; Y259-Y542 AromaticContact CG-CE2 3.45Å; Y259-Y542 HydrophobicContact CG-CE2 3.45Å; Y259-Y542 VanDerWaalsContact CG-CE2 3.45Å; Y259-Y542 AromaticContact CG-CZ 3.46Å; Y259-Y542 VanDerWaalsContact CG-CZ 3.46Å; Y259-T569 WeakPolarHBondContact O-CG2 3.35Å
260D97.3Very high96.7Very high33 Ų3339.5 Ų39.518%0.17620%0.197CC..Hα-helixtrans-81.9-45.9172.7-169.619.4000111.6H250 A256 M257 A258 R406 P570H250-D260 IonicContact CD2-OD2 2.75Å; H250-D260 PolarHBondContact CD2-OD2 3.49Å; H250-D260 IonicContact CG-OD2 2.78Å; H250-D260 IonicContact NE2-OD2 2.85Å; A256-D260 VanDerWaalsContact O-CB 3.3Å; A256-D260 WeakPolarHBondContact O-CB 3.42Å; A256-D260 PolarHBondContact O-N 2.8Å; M257-D260 PolarHBondContact O-N 3.44Å; A258-D260 VanDerWaalsContact C-N 3.32Å; A258-D260 PolarHBondContact O-N 3.17Å; D260-R406 IonicContact OD1-CZ 2.62Å; D260-R406 IonicContact OD1-NH1 2.61Å; D260-R406 PolarHBondContact OD1-NH1 3.41Å; D260-R406 IonicContact OD1-NH2 3.72Å; D260-R406 IonicContact OD2-CZ 2.79Å; D260-R406 IonicContact OD2-NH1 2.62Å; D260-R406 PolarHBondContact OD2-NH1 2.91Å; D260-R406 VanDerWaalsContact OD2-NH1 3.16Å; D260-R406 IonicContact OD2-NH2 3Å; D260-R406 PolarHBondContact OD2-NH2 3.37Å; D260-P570 WeakPolarHBondContact OD1-CG 3.49Å
261L96.6Very high96.5Very high26 Ų2640.4 Ų40.414%0.13620%0.201CC..Hα-helixtrans-92.8-21.4-169-59.6-175000114.9M257 K357 I362M257-L261 HydrophobicContact CE-CD1 3.69Å; M257-L261 HydrophobicContact CG-CD1 3.66Å; M257-L261 HydrophobicContact CG-CG 4.3Å; M257-L261 WeakPolarHBondContact O-CB 3.29Å; M257-L261 WeakPolarHBondContact O-CG 3.39Å; M257-L261 PolarHBondContact O-N 3.4Å; L261-K357 HydrophobicContact CB-CB 4.28Å; L261-K357 HydrophobicContact CD1-CB 4.24Å; L261-I362 HydrophobicContact CD2-CG1 4.11Å
262L97Very high96.2Very high18 Ų1845.7 Ų45.79%0.09422%0.223CC..SBendtrans-116.1150.1-172.6-53.2179000111.6A258 I264 Y269 L350 D353 K357A258-L262 VanDerWaalsContact O-CB 3.26Å; A258-L262 WeakPolarHBondContact O-CB 3.41Å; A258-L262 PolarHBondContact O-N 3.09Å; L262-I264 HydrophobicContact CB-CD1 4.41Å; L262-I264 HydrophobicContact CB-CG1 4.18Å; L262-I264 PolarHBondContact O-N 2.95Å; L262-Y269 HydrophobicContact CD1-CE2 4.14Å; L262-L350 HydrophobicContact CD1-CD1 3.48Å; L262-L350 VanDerWaalsContact CD1-CD1 3.48Å; L262-D353 HydrophobicContact CD1-CB 4.01Å; L262-D353 HydrophobicContact CD2-CB 3.91Å; L262-K357 HydrophobicContact CD2-CG 4.17Å
263P95.4Very high95.6Very high114 Ų11445.5 Ų45.574%0.7422%0.223SC*.  trans-77.967-179.934-36.5000111.1
264I97.2Very high94.9Very high17 Ų1750 Ų509%0.08725%0.246CC..  trans-86.5120176.6-60.6173000108.7A258 Y259 L262 L282 L350A258-I264 HydrophobicContact CB-CD1 3.93Å; Y259-I264 HydrophobicContact CD1-CB 4.11Å; Y259-I264 HydrophobicContact CD1-CG2 3.94Å; Y259-I264 HydrophobicContact CD2-CD1 4.25Å; Y259-I264 HydrophobicContact CE1-CB 4.22Å; Y259-I264 HydrophobicContact CE1-CG2 3.53Å; Y259-I264 HydrophobicContact CE2-CD1 4.42Å; Y259-I264 HydrophobicContact CG-CD1 4.32Å; L262-I264 HydrophobicContact CB-CD1 4.41Å; L262-I264 HydrophobicContact CB-CG1 4.18Å; L262-I264 PolarHBondContact O-N 2.95Å; I264-L282 HydrophobicContact CD1-CD1 3.9Å; I264-L350 HydrophobicContact CD1-CD1 4.37Å
265E92Very high94.2Very high142 Ų14253.7 Ų53.766%0.66428%0.284SS*.BIsolated β-bridgetrans-119.2128.4178-68.7-176-175.300110.1D267 T268E265-D267 PolarHBondContact O-N 2.73Å; E265-T268 PolarHBondContact N-O 2.58Å; E265-T268 WeakPolarHBondContact O-CA 3.43Å; E265-T268 VanDerWaalsContact O-CB 3.24Å; E265-T268 WeakPolarHBondContact O-CB 3.17Å; E265-T268 PolarHBondContact O-N 3.18Å
266K90.2Very high93.7Very high194 Ų19460.7 Ų60.784%0.84332%0.315SS*.THydrogen-bonded Turntrans48.147.2-179.3-55.3179.4-176.8175.10111.6T268K266-T268 PolarHBondContact O-N 3.47Å; K266-T268 PolarHBondContact O-OG1 2.81Å
267D94.4Very high93.5Very high44 Ų4467.2 Ų67.224%0.23534%0.344CS..THydrogen-bonded Turntrans59.112.5-178.8-49.4-42.9000114.7H143 Y259 E265 V281 L282H143-D267 IonicContact CE1-OD2 3.65Å; Y259-D267 WeakPolarHBondContact CE1-OD1 3.37Å; Y259-D267 PolarHBondContact OH-OD1 3.49Å; E265-D267 PolarHBondContact O-N 2.73Å; D267-V281 CarbonylContact O-C 3.52Å; D267-V281 WeakPolarHBondContact O-CA 3.48Å; D267-L282 PolarHBondContact O-N 3.47Å
268T96.8Very high93.3Very high32 Ų3271 Ų7120%0.19636%0.36CS..EExtended strand (participates in β ladder)trans-94.7112.9178.8-560000109.9E265 K266 E279 A280E265-T268 PolarHBondContact N-O 2.58Å; E265-T268 WeakPolarHBondContact O-CA 3.43Å; E265-T268 VanDerWaalsContact O-CB 3.24Å; E265-T268 WeakPolarHBondContact O-CB 3.17Å; E265-T268 PolarHBondContact O-N 3.18Å; K266-T268 PolarHBondContact O-N 3.47Å; K266-T268 PolarHBondContact O-OG1 2.81Å; T268-E279 HydrophobicContact CG2-CB 4.01Å; T268-A280 WeakPolarHBondContact CA-O 3.42Å
269Y97.3Very high93.2Very high5 Ų576.8 Ų76.82%0.0239%0.387CS..EExtended strand (participates in β ladder)trans-95126.9173.5168-125.3000110.2L262 Y271 E279 A280 V346 N349 L350 D353L262-Y269 HydrophobicContact CD1-CE2 4.14Å; Y269-Y271 AromaticContact CD1-CD1 3.88Å; Y269-Y271 HydrophobicContact CD1-CD1 3.88Å; Y269-Y271 HydrophobicContact CD1-CG 4.38Å; Y269-Y271 AromaticContact CE1-CD1 3.78Å; Y269-Y271 HydrophobicContact CE1-CD1 3.78Å; Y269-Y271 AromaticContact CE1-CG 3.81Å; Y269-Y271 HydrophobicContact CE1-CG 3.81Å; Y269-Y271 VanDerWaalsContact CZ-CB 3.42Å; Y269-Y271 VanDerWaalsContact OH-CB 3.29Å; Y269-Y271 WeakPolarHBondContact OH-CB 3.13Å; Y269-E279 CarbonylContact O-C 3.6Å; Y269-E279 WeakPolarHBondContact O-CA 3.05Å; Y269-A280 PolarHBondContact N-O 3.25Å; Y269-A280 PolarHBondContact O-N 2.87Å; Y269-V346 HydrophobicContact CD1-CG1 4.17Å; Y269-N349 HydrophobicContact CE1-CB 4.45Å; Y269-N349 PolarHBondContact OH-O 2.91Å; Y269-L350 HydrophobicContact CD1-CB 4.22Å; Y269-L350 HydrophobicContact CD1-CD1 3.89Å; Y269-L350 HydrophobicContact CD2-CD1 3.66Å; Y269-L350 HydrophobicContact CE1-CB 3.68Å; Y269-L350 HydrophobicContact CE1-CD1 3.86Å; Y269-L350 HydrophobicContact CE1-CG 4.36Å; Y269-L350 HydrophobicContact CE2-CD1 3.67Å; Y269-L350 HydrophobicContact CG-CD1 3.78Å; Y269-L350 WeakPolarHBondContact OH-CA 3.4Å; Y269-L350 PolarHBondContact OH-N 2.74Å; Y269-D353 PolarHBondContact OH-OD2 3.3Å
270K96.6Very high93Very high132 Ų13276.7 Ų76.757%0.57439%0.39SS*.EExtended strand (participates in β ladder)trans-104.4128.7177.3-51.1-165.1-176.5-151.30109.9K278 E279K270-K278 WeakPolarHBondContact CA-O 3.21Å; K270-E279 HydrophobicContact CD-CG 4.36Å; K270-E279 WeakPolarHBondContact CD-OE1 3.37Å; K270-E279 WeakPolarHBondContact CE-OE1 3.05Å; K270-E279 HydrophobicContact CG-CG 4.04Å; K270-E279 IonicContact NZ-OE1 3.75Å; K270-E279 PolarHBondContact NZ-OE1 3.25Å
271Y93.8Very high92.9Very high23 Ų2378.8 Ų78.89%0.0940%0.404CS..EExtended strand (participates in β ladder)trans-143.6162-174.768-78000112.4Y269 T273 K278 A280 V345 V346 N349Y269-Y271 AromaticContact CD1-CD1 3.88Å; Y269-Y271 HydrophobicContact CD1-CD1 3.88Å; Y269-Y271 HydrophobicContact CD1-CG 4.38Å; Y269-Y271 AromaticContact CE1-CD1 3.78Å; Y269-Y271 HydrophobicContact CE1-CD1 3.78Å; Y269-Y271 AromaticContact CE1-CG 3.81Å; Y269-Y271 HydrophobicContact CE1-CG 3.81Å; Y269-Y271 VanDerWaalsContact CZ-CB 3.42Å; Y269-Y271 VanDerWaalsContact OH-CB 3.29Å; Y269-Y271 WeakPolarHBondContact OH-CB 3.13Å; Y271-T273 WeakPolarHBondContact CD2-OG1 3.26Å; Y271-T273 VanDerWaalsContact CE2-OG1 3.29Å; Y271-T273 WeakPolarHBondContact CE2-OG1 3.46Å; Y271-K278 HydrophobicContact CD1-CB 4.24Å; Y271-K278 HydrophobicContact CE1-CB 3.73Å; Y271-K278 HydrophobicContact CE2-CB 4.07Å; Y271-K278 HydrophobicContact CE2-CD 4.02Å; Y271-K278 PolarHBondContact N-O 3.43Å; Y271-K278 PolarHBondContact O-N 3.48Å; Y271-A280 HydrophobicContact CE1-CB 3.89Å; Y271-V345 HydrophobicContact CE2-CG1 4.31Å; Y271-V346 HydrophobicContact CE1-CG2 3.95Å; Y271-V346 WeakPolarHBondContact OH-CG2 3.44Å; Y271-N349 HydrophobicContact CD2-CB 3.95Å; Y271-N349 HydrophobicContact CG-CB 4.36Å
272K90Very high92.8Very high133 Ų13378 Ų7858%0.57840%0.4SS*.EExtended strand (participates in β ladder)trans-111.2126.7179.6-71.7-178.3178.6-175.50110.4K276 E277 N349K272-K276 WeakPolarHBondContact CA-O 3.43Å; K272-E277 HydrophobicContact CD-CG 4.29Å; K272-E277 VanDerWaalsContact CE-CG 3.42Å; K272-E277 WeakPolarHBondContact CE-OE1 3.45Å; K272-E277 HydrophobicContact CG-CG 3.86Å; K272-E277 IonicContact NZ-OE1 3.84Å; K272-E277 PolarHBondContact NZ-OE1 3.06Å; K272-N349 PolarHBondContact O-OD1 3.05Å
273T84.9Confident92.5Very high2 Ų281.5 Ų81.51%0.01242%0.416CS..EExtended strand (participates in β ladder)trans-134.5129.2171.1-56.60000109.2Y271 G275 K276 L324Y271-T273 WeakPolarHBondContact CD2-OG1 3.26Å; Y271-T273 VanDerWaalsContact CE2-OG1 3.29Å; Y271-T273 WeakPolarHBondContact CE2-OG1 3.46Å; T273-G275 PolarHBondContact O-N 2.71Å; T273-K276 PolarHBondContact N-O 3.21Å; T273-K276 PolarHBondContact O-N 2.87Å; T273-L324 HydrophobicContact CG2-CD1 4.28Å; T273-L324 HydrophobicContact CG2-CD2 4.13Å; T273-L324 HydrophobicContact CG2-CG 4.22Å
274D82.7Confident92.2Very high103 Ų10376.7 Ų76.755%0.55138%0.383SS*.THydrogen-bonded Turntrans52.838-176.5-55.5-41.5000113.1K276 T328D274-K276 PolarHBondContact O-N 3.33Å; D274-T328 WeakPolarHBondContact OD2-CG2 3.11Å; D274-T328 PolarHBondContact OD2-OG1 3.14Å
275G84.5Confident91.7Very high78 Ų7879.5 Ų79.580%0.80440%0.399SS*.THydrogen-bonded Turntrans740.3-178.300000115.3T273T273-G275 PolarHBondContact O-N 2.71Å
276K88.9Confident91.7Very high149 Ų14973.4 Ų73.465%0.64837%0.371SS*.EExtended strand (participates in β ladder)trans-100.3131.3177.6-63.1-175.6179.9-174.80110.9K272 T273 D274K272-K276 WeakPolarHBondContact CA-O 3.43Å; T273-K276 PolarHBondContact N-O 3.21Å; T273-K276 PolarHBondContact O-N 2.87Å; D274-K276 PolarHBondContact O-N 3.33Å
277E93.1Very high91.7Very high148 Ų14869.5 Ų69.569%0.69236%0.359SS*.EExtended strand (participates in β ladder)trans-71135.5168.1-73.2-179.4-177.800110.1K272K272-E277 HydrophobicContact CD-CG 4.29Å; K272-E277 VanDerWaalsContact CE-CG 3.42Å; K272-E277 WeakPolarHBondContact CE-OE1 3.45Å; K272-E277 HydrophobicContact CG-CG 3.86Å; K272-E277 IonicContact NZ-OE1 3.84Å; K272-E277 PolarHBondContact NZ-OE1 3.06Å
278K94.4Very high91.6Very high80 Ų8068.4 Ų68.435%0.34835%0.353SS..EExtended strand (participates in β ladder)trans-137.7157.2178.8-66.1-179.2-175.8171.40108.6K270 Y271K270-K278 WeakPolarHBondContact CA-O 3.21Å; Y271-K278 HydrophobicContact CD1-CB 4.24Å; Y271-K278 HydrophobicContact CE1-CB 3.73Å; Y271-K278 HydrophobicContact CE2-CB 4.07Å; Y271-K278 HydrophobicContact CE2-CD 4.02Å; Y271-K278 PolarHBondContact N-O 3.43Å; Y271-K278 PolarHBondContact O-N 3.48Å
279E95Very high91.5Very high121 Ų12167 Ų6757%0.56534%0.344SS*.EExtended strand (participates in β ladder)trans-123.5145.7175.9-54.2-171.6155.500108.7T268 Y269 K270T268-E279 HydrophobicContact CG2-CB 4.01Å; Y269-E279 CarbonylContact O-C 3.6Å; Y269-E279 WeakPolarHBondContact O-CA 3.05Å; K270-E279 HydrophobicContact CD-CG 4.36Å; K270-E279 WeakPolarHBondContact CD-OE1 3.37Å; K270-E279 WeakPolarHBondContact CE-OE1 3.05Å; K270-E279 HydrophobicContact CG-CG 4.04Å; K270-E279 IonicContact NZ-OE1 3.75Å; K270-E279 PolarHBondContact NZ-OE1 3.25Å
280A95.2Very high91.4Very high16 Ų1669.1 Ų69.113%0.13236%0.357CS..EExtended strand (participates in β ladder)trans-138.3139.9173.300000109.4T268 Y269 Y271 V346T268-A280 WeakPolarHBondContact CA-O 3.42Å; Y269-A280 PolarHBondContact N-O 3.25Å; Y269-A280 PolarHBondContact O-N 2.87Å; Y271-A280 HydrophobicContact CE1-CB 3.89Å; A280-V346 HydrophobicContact CB-CB 4.34Å; A280-V346 HydrophobicContact CB-CG1 3.59Å; A280-V346 HydrophobicContact CB-CG2 3.7Å
281V94Very high91.2Very high78 Ų7868.6 Ų68.647%0.47335%0.352SS..EExtended strand (participates in β ladder)trans-91.2129173.5-176.40000108.3D267 E283D267-V281 CarbonylContact O-C 3.52Å; D267-V281 WeakPolarHBondContact O-CA 3.48Å; V281-E283 HydrophobicContact CG1-CB 4.36Å; V281-E283 PolarHBondContact O-N 3.27Å
282L95.1Very high91.3Very high10 Ų1067.5 Ų67.55%0.05235%0.347CS..  trans-87.8102.9176.8-56.5179.8000108.8Y259 I264 D267 W289 L350Y259-L282 HydrophobicContact CE2-CD1 4.14Å; I264-L282 HydrophobicContact CD1-CD1 3.9Å; D267-L282 PolarHBondContact O-N 3.47Å; L282-W289 HydrophobicContact CB-CZ2 4.25Å; L282-W289 HydrophobicContact CD1-CH2 4.04Å; L282-W289 HydrophobicContact CD1-CZ2 4.21Å; L282-L350 HydrophobicContact CD1-CD2 4.15Å; L282-L350 HydrophobicContact CD2-CD2 4.04Å
283E90.6Very high91.7Very high91 Ų9161.3 Ų61.343%0.42532%0.32SS..  trans-138.3159.5-170.161.4-176.1-171.500113.5V281 D285 D286V281-E283 HydrophobicContact CG1-CB 4.36Å; V281-E283 PolarHBondContact O-N 3.27Å; E283-D285 HydrophobicContact CG-CB 4.32Å; E283-D285 PolarHBondContact O-N 2.94Å; E283-D286 WeakPolarHBondContact O-CB 3.32Å; E283-D286 PolarHBondContact O-N 2.63Å
284E89.5Confident92.3Very high13 Ų1362.8 Ų62.86%0.06133%0.327CS..THydrogen-bonded Turntrans-62.4-23.1-179-75.8-79.183.800113.9K11 E144 S145 D286 V290 R293K11-E284 HydrophobicContact CD-CB 4.34Å; K11-E284 HydrophobicContact CD-CG 4.11Å; E144-E284 HydrophobicContact CB-CG 4.32Å; S145-E284 WeakPolarHBondContact CB-OE2 3.29Å; S145-E284 PolarHBondContact N-OE2 3.14Å; S145-E284 PolarHBondContact OG-OE2 2.92Å; E284-D286 PolarHBondContact O-N 3.12Å; E284-V290 VanDerWaalsContact O-CG2 3.28Å; E284-V290 WeakPolarHBondContact O-CG2 3.36Å; E284-V290 VanDerWaalsContact OE1-CG2 3.31Å; E284-V290 WeakPolarHBondContact OE1-CG2 3.16Å; E284-R293 IonicContact OE1-CZ 2.8Å; E284-R293 IonicContact OE1-NH1 2.69Å; E284-R293 PolarHBondContact OE1-NH1 2.83Å; E284-R293 IonicContact OE1-NH2 3.53Å; E284-R293 PolarHBondContact OE1-NH2 2.95Å; E284-R293 IonicContact OE2-NH2 2.76Å
285D86.6Confident93Very high76 Ų7663 Ų6341%0.40632%0.32SS..THydrogen-bonded Turntrans-73.4-4.9175.8-73.4-0.5000112.6K50 E283 K343K50-D285 WeakPolarHBondContact CE-OD2 3.44Å; K50-D285 IonicContact NZ-OD2 2.74Å; K50-D285 PolarHBondContact NZ-OD2 2.71Å; E283-D285 HydrophobicContact CG-CB 4.32Å; E283-D285 PolarHBondContact O-N 2.94Å; D285-K343 PolarHBondContact O-NZ 2.94Å
286D91.4Very high93.6Very high14 Ų1460.6 Ų60.68%0.07529%0.288CS..  trans-91.491.5166.5-163.2-5.2000113.2E283 E284 L288 W289 V290 K343 H347E283-D286 WeakPolarHBondContact O-CB 3.32Å; E283-D286 PolarHBondContact O-N 2.63Å; E284-D286 PolarHBondContact O-N 3.12Å; D286-L288 PolarHBondContact O-N 2.81Å; D286-L288 PolarHBondContact OD1-N 2.86Å; D286-L288 VanDerWaalsContact OD1-N 3.08Å; D286-W289 HydrophobicContact CB-CB 3.77Å; D286-W289 WeakPolarHBondContact O-CA 3.02Å; D286-W289 VanDerWaalsContact O-CB 3.27Å; D286-W289 WeakPolarHBondContact O-CB 2.96Å; D286-W289 PolarHBondContact O-N 3.21Å; D286-V290 WeakPolarHBondContact O-CG2 3.44Å; D286-V290 PolarHBondContact O-N 3.29Å; D286-K343 VanDerWaalsContact OD1-CD 3.23Å; D286-K343 WeakPolarHBondContact OD1-CD 3.41Å; D286-K343 WeakPolarHBondContact OD1-CE 3.21Å; D286-K343 IonicContact OD1-NZ 2.99Å; D286-K343 PolarHBondContact OD1-NZ 2.83Å; D286-K343 WeakPolarHBondContact OD2-CG 3.36Å; D286-H347 IonicContact OD2-CD2 3.48Å; D286-H347 IonicContact OD2-CE1 2.75Å; D286-H347 IonicContact OD2-NE2 3.33Å; D286-H347 PolarHBondContact OD2-NE2 3.17Å
287D90.6Very high94Very high112 Ų11253.8 Ų53.860%0.59926%0.258SS*.Hα-helixtrans-48.5-34.6174.8-56.3-51.5000113.7R291D287-R291 WeakPolarHBondContact O-CB 3.18Å; D287-R291 PolarHBondContact O-N 3.08Å; D287-R291 VanDerWaalsContact O-N 3.1Å
288L91.9Very high94.1Very high20 Ų2048.6 Ų48.611%0.10524%0.24CC..Hα-helixtrans-69.9-46.3177.2178.854.5000110.4D286 R291 V292 L307 Q344 H347D286-L288 PolarHBondContact O-N 2.81Å; D286-L288 PolarHBondContact OD1-N 2.86Å; D286-L288 VanDerWaalsContact OD1-N 3.08Å; L288-R291 WeakPolarHBondContact O-CB 3.29Å; L288-R291 PolarHBondContact O-N 3.44Å; L288-V292 HydrophobicContact CD1-CG1 4Å; L288-V292 VanDerWaalsContact O-CG2 3.25Å; L288-V292 WeakPolarHBondContact O-CG2 3.37Å; L288-V292 PolarHBondContact O-N 2.97Å; L288-L307 HydrophobicContact CD1-CD1 3.62Å; L288-Q344 HydrophobicContact CD2-CB 4.34Å; L288-Q344 HydrophobicContact CD2-CG 3.6Å; L288-H347 HydrophobicContact CD2-CB 4.46Å
289W95.6Very high94.2Very high4 Ų447.2 Ų47.22%0.01524%0.239CC..Hα-helixtrans-55.4-54.4175177.9-119.3000111F254 Q255 Y259 L282 D286 R291 V292 R293 H347 L350F254-W289 HydrophobicContact CD1-CE3 4.27Å; F254-W289 AromaticContact CD1-CZ3 3.77Å; F254-W289 HydrophobicContact CD1-CZ3 3.77Å; F254-W289 HydrophobicContact CE1-CE3 4.05Å; F254-W289 AromaticContact CE1-CZ3 3.68Å; F254-W289 HydrophobicContact CE1-CZ3 3.68Å; F254-W289 HydrophobicContact CG-CZ3 4.5Å; F254-W289 HydrophobicContact CZ-CZ3 4.34Å; Q255-W289 HydrophobicContact CB-CH2 4.11Å; Q255-W289 HydrophobicContact CB-CZ2 4.17Å; Q255-W289 HydrophobicContact CG-CH2 4.16Å; Q255-W289 HydrophobicContact CG-CZ2 3.83Å; Y259-W289 HydrophobicContact CE2-CZ2 4.31Å; L282-W289 HydrophobicContact CB-CZ2 4.25Å; L282-W289 HydrophobicContact CD1-CH2 4.04Å; L282-W289 HydrophobicContact CD1-CZ2 4.21Å; D286-W289 HydrophobicContact CB-CB 3.77Å; D286-W289 WeakPolarHBondContact O-CA 3.02Å; D286-W289 VanDerWaalsContact O-CB 3.27Å; D286-W289 WeakPolarHBondContact O-CB 2.96Å; D286-W289 PolarHBondContact O-N 3.21Å; W289-R291 PolarHBondContact O-N 3.13Å; W289-R291 VanDerWaalsContact O-N 3.15Å; W289-V292 PolarHBondContact O-N 2.86Å; W289-R293 HydrophobicContact CD2-CB 3.88Å; W289-R293 HydrophobicContact CE3-CB 4.08Å; W289-R293 HydrophobicContact CG-CB 4.48Å; W289-R293 HydrophobicContact CH2-CB 4.13Å; W289-R293 HydrophobicContact CZ2-CB 3.91Å; W289-R293 HydrophobicContact CZ3-CB 4.2Å; W289-R293 WeakPolarHBondContact O-CB 3.28Å; W289-R293 WeakPolarHBondContact O-CG 3.23Å; W289-R293 PolarHBondContact O-N 2.82Å; W289-H347 AromaticContact CE3-CE1 3.59Å; W289-H347 AromaticContact CE3-ND1 3.69Å; W289-L350 HydrophobicContact CH2-CD2 4.33Å; W289-L350 HydrophobicContact CZ3-CD2 3.73Å
290V94.9Very high94.3Very high48 Ų4841.5 Ų41.529%0.29121%0.212SC..Hα-helixtrans-54.8-38.5179.3179.90000111.7E284 D286E284-V290 VanDerWaalsContact O-CG2 3.28Å; E284-V290 WeakPolarHBondContact O-CG2 3.36Å; E284-V290 VanDerWaalsContact OE1-CG2 3.31Å; E284-V290 WeakPolarHBondContact OE1-CG2 3.16Å; D286-V290 WeakPolarHBondContact O-CG2 3.44Å; D286-V290 PolarHBondContact O-N 3.29Å
291R93.5Very high94.2Very high122 Ų12243.6 Ų43.646%0.4622%0.221SC..Hα-helixtrans-69.6-36.2179.6177.8174.8170.9168.6-2.4113.8D287 L288 W289 R295 E303D287-R291 WeakPolarHBondContact O-CB 3.18Å; D287-R291 PolarHBondContact O-N 3.08Å; D287-R291 VanDerWaalsContact O-N 3.1Å; L288-R291 WeakPolarHBondContact O-CB 3.29Å; L288-R291 PolarHBondContact O-N 3.44Å; W289-R291 PolarHBondContact O-N 3.13Å; W289-R291 VanDerWaalsContact O-N 3.15Å; R291-R295 PolarHBondContact O-NE 2.95Å; R291-E303 IonicContact CZ-OE1 3.12Å; R291-E303 IonicContact NE-OE1 3.72Å; R291-E303 PolarHBondContact NE-OE1 2.9Å; R291-E303 IonicContact NH2-OE1 3.13Å; R291-E303 PolarHBondContact NH2-OE1 3.02Å
292V95.8Very high94.2Very high0 Ų045.3 Ų45.30%022%0.223CC..Hα-helixtrans-106.9-20.5-171.3-60.10000115.2F254 L288 W289 H294 R295 V300F254-V292 HydrophobicContact CD1-CB 4.33Å; F254-V292 HydrophobicContact CD1-CG2 3.65Å; F254-V292 HydrophobicContact CE1-CG2 3.74Å; L288-V292 HydrophobicContact CD1-CG1 4Å; L288-V292 VanDerWaalsContact O-CG2 3.25Å; L288-V292 WeakPolarHBondContact O-CG2 3.37Å; L288-V292 PolarHBondContact O-N 2.97Å; W289-V292 PolarHBondContact O-N 2.86Å; V292-H294 PolarHBondContact O-N 2.77Å; V292-H294 VanDerWaalsContact O-N 3.11Å; V292-R295 WeakPolarHBondContact O-CB 2.97Å; V292-R295 PolarHBondContact O-N 3.48Å; V292-V300 HydrophobicContact CB-CG1 4.29Å; V292-V300 HydrophobicContact CB-CG2 3.98Å; V292-V300 HydrophobicContact CG2-CG1 4.4Å
293R97.2Very high94Very high3 Ų345.5 Ų45.51%0.01122%0.224CC..THydrogen-bonded Turntrans-58-31.5-17071.3172.4-179.7-155.2-18.3114.7E144 F254 Q255 E284 W289 Y549E144-R293 IonicContact OE1-CZ 3.69Å; E144-R293 IonicContact OE1-NE 3.56Å; E144-R293 IonicContact OE1-NH1 3.67Å; E144-R293 PolarHBondContact OE1-NH1 2.68Å; E144-R293 IonicContact OE2-CZ 3.42Å; E144-R293 IonicContact OE2-NE 3.89Å; E144-R293 IonicContact OE2-NH1 2.75Å; E144-R293 IonicContact OE2-NH2 3.05Å; E144-R293 PolarHBondContact OE2-NH2 3.08Å; F254-R293 PolarHBondContact N-O 2.98Å; Q255-R293 HydrophobicContact CB-CB 4.04Å; Q255-R293 VanDerWaalsContact CB-O 3.24Å; Q255-R293 WeakPolarHBondContact CB-O 3.45Å; Q255-R293 PolarHBondContact N-O 3.02Å; E284-R293 IonicContact OE1-CZ 2.8Å; E284-R293 IonicContact OE1-NH1 2.69Å; E284-R293 PolarHBondContact OE1-NH1 2.83Å; E284-R293 IonicContact OE1-NH2 3.53Å; E284-R293 PolarHBondContact OE1-NH2 2.95Å; E284-R293 IonicContact OE2-NH2 2.76Å; W289-R293 HydrophobicContact CD2-CB 3.88Å; W289-R293 HydrophobicContact CE3-CB 4.08Å; W289-R293 HydrophobicContact CG-CB 4.48Å; W289-R293 HydrophobicContact CH2-CB 4.13Å; W289-R293 HydrophobicContact CZ2-CB 3.91Å; W289-R293 HydrophobicContact CZ3-CB 4.2Å; W289-R293 WeakPolarHBondContact O-CB 3.28Å; W289-R293 WeakPolarHBondContact O-CG 3.23Å; W289-R293 PolarHBondContact O-N 2.82Å; R293-Y549 PolarHBondContact NH2-OH 2.83Å
294H97.6Very high93.9Very high32 Ų3241.2 Ų41.215%0.14820%0.204CC..THydrogen-bonded Turntrans-96.22.1-179.9-63.8-40.8000113.4Q255 V292 R546 Y549Q255-H294 PolarHBondContact OE1-CE1 3.39Å; Q255-H294 PolarHBondContact OE1-ND1 3.31Å; V292-H294 PolarHBondContact O-N 2.77Å; V292-H294 VanDerWaalsContact O-N 3.11Å; H294-R546 HydrophobicContact CB-CG 3.96Å; H294-R546 WeakPolarHBondContact O-CD 3.48Å; H294-Y549 AromaticContact CD2-CD2 3.83Å; H294-Y549 AromaticContact CD2-CG 3.92Å; H294-Y549 AromaticContact CE1-CD2 3.8Å; H294-Y549 AromaticContact CE1-CE2 3.9Å; H294-Y549 AromaticContact NE2-CD2 3.19Å; H294-Y549 WeakPolarHBondContact NE2-CD2 3.43Å; H294-Y549 AromaticContact NE2-CE2 3.32Å; H294-Y549 VanDerWaalsContact NE2-CE2 3.32Å; H294-Y549 WeakPolarHBondContact NE2-CE2 3.36Å; H294-Y549 AromaticContact NE2-CG 3.7Å; H294-Y549 AromaticContact NE2-CZ 3.92Å
295R97.5Very high93.7Very high109 Ų10941.8 Ų41.841%0.41121%0.209SC..SBendtrans-90151.9179.6-61.7-174.9175.2-125.6-15.6110.7T253 F254 R291 V292 V300 E303T253-R295 WeakPolarHBondContact CA-O 3.35Å; F254-R295 PolarHBondContact N-O 3.35Å; R291-R295 PolarHBondContact O-NE 2.95Å; V292-R295 WeakPolarHBondContact O-CB 2.97Å; V292-R295 PolarHBondContact O-N 3.48Å; R295-V300 HydrophobicContact CB-CG2 3.85Å; R295-E303 WeakPolarHBondContact CD-OE2 3.43Å; R295-E303 IonicContact CZ-OE1 3.99Å; R295-E303 IonicContact CZ-OE2 3.86Å; R295-E303 IonicContact NE-OE2 3.92Å; R295-E303 PolarHBondContact NE-OE2 3.33Å; R295-E303 IonicContact NH1-OE1 3.33Å; R295-E303 IonicContact NH1-OE2 2.91Å; R295-E303 PolarHBondContact NH1-OE2 3Å
296H98Very high93.7Very high27 Ų2743.4 Ų43.413%0.12521%0.213CC..BIsolated β-bridgetrans-62140.8172.8-172.4-93.4000111L252 A298 V299 V300 F469 S472L252-H296 WeakPolarHBondContact CB-NE2 3.23Å; L252-H296 WeakPolarHBondContact O-CA 3.17Å; H296-A298 WeakPolarHBondContact ND1-CB 3.37Å; H296-A298 PolarHBondContact ND1-N 3.25Å; H296-A298 PolarHBondContact O-N 2.93Å; H296-A298 VanDerWaalsContact O-N 3.12Å; H296-V299 HydrophobicContact CB-CG2 4.43Å; H296-V299 WeakPolarHBondContact O-CA 2.94Å; H296-V299 WeakPolarHBondContact O-CB 3.49Å; H296-V299 PolarHBondContact O-N 3.24Å; H296-V300 PolarHBondContact O-N 3.44Å; H296-V300 VanDerWaalsContact O-N 3.11Å; H296-F469 HydrophobicContact CB-CD2 4.1Å; H296-F469 HydrophobicContact CB-CE2 3.64Å; H296-F469 HydrophobicContact CB-CZ 4.16Å; H296-F469 AromaticContact CD2-CD2 3.77Å; H296-F469 AromaticContact CE1-CD1 3.64Å; H296-F469 AromaticContact CE1-CE1 3.95Å; H296-F469 AromaticContact CE1-CG 3.7Å; H296-F469 AromaticContact CG-CD2 3.64Å; H296-F469 AromaticContact CG-CE2 3.57Å; H296-F469 AromaticContact CG-CZ 3.96Å; H296-F469 AromaticContact ND1-CD1 3.79Å; H296-F469 AromaticContact ND1-CD2 3.81Å; H296-F469 AromaticContact ND1-CE1 3.65Å; H296-F469 AromaticContact ND1-CE2 3.68Å; H296-F469 AromaticContact ND1-CG 3.87Å; H296-F469 AromaticContact ND1-CZ 3.6Å; H296-F469 AromaticContact NE2-CG 3.8Å; H296-S472 PolarHBondContact NE2-OG 3.31Å
297I97.5Very high93.3Very high6 Ų643.7 Ų43.73%0.03121%0.214CC..Hα-helixtrans-55.4-35.3-174.2-172.159.4000113.1L252 F254 M257 V299 V300 L301 A351 M355L252-I297 HydrophobicContact CB-CG2 4.19Å; L252-I297 PolarHBondContact O-N 2.96Å; F254-I297 HydrophobicContact CD2-CD1 3.85Å; F254-I297 HydrophobicContact CE2-CD1 4.25Å; M257-I297 HydrophobicContact SD-CB 3.87Å; M257-I297 HydrophobicContact SD-CD1 4.46Å; M257-I297 HydrophobicContact SD-CG1 3.93Å; M257-I297 HydrophobicContact SD-CG2 3.99Å; I297-V299 VanDerWaalsContact C-N 3.3Å; I297-V299 PolarHBondContact O-N 3.16Å; I297-V300 HydrophobicContact CD1-CB 4.44Å; I297-V300 PolarHBondContact O-N 3.42Å; I297-L301 HydrophobicContact CD1-CG 4.37Å; I297-L301 HydrophobicContact CG1-CD1 4.19Å; I297-L301 HydrophobicContact CG1-CG 4.34Å; I297-L301 VanDerWaalsContact O-CG 3.3Å; I297-L301 WeakPolarHBondContact O-CG 3.1Å; I297-L301 PolarHBondContact O-N 3.26Å; I297-A351 HydrophobicContact CD1-CB 3.97Å; I297-M355 HydrophobicContact CG1-CG 4.1Å; I297-M355 HydrophobicContact CG1-SD 3.55Å; I297-M355 VanDerWaalsContact CG1-SD 3.55Å; I297-M355 HydrophobicContact CG2-SD 4.09Å
298A95.3Very high92.5Very high38 Ų3838.6 Ų38.631%0.31419%0.186SC..Hα-helixtrans-60-39.6175.200000112.4H296 E302 F469H296-A298 WeakPolarHBondContact ND1-CB 3.37Å; H296-A298 PolarHBondContact ND1-N 3.25Å; H296-A298 PolarHBondContact O-N 2.93Å; H296-A298 VanDerWaalsContact O-N 3.12Å; A298-E302 PolarHBondContact O-N 3.35Å; A298-F469 HydrophobicContact CB-CE1 3.82Å; A298-F469 HydrophobicContact CB-CZ 4.26Å
299V96.2Very high91.8Very high52 Ų5243.2 Ų43.232%0.31521%0.206SC..Hα-helixtrans-70.2-41.8176.1-178.20000110.1H296 I297 L301 E302 E303 F469H296-V299 HydrophobicContact CB-CG2 4.43Å; H296-V299 WeakPolarHBondContact O-CA 2.94Å; H296-V299 WeakPolarHBondContact O-CB 3.49Å; H296-V299 PolarHBondContact O-N 3.24Å; I297-V299 VanDerWaalsContact C-N 3.3Å; I297-V299 PolarHBondContact O-N 3.16Å; V299-L301 PolarHBondContact O-N 3.23Å; V299-E302 PolarHBondContact O-N 3Å; V299-E302 VanDerWaalsContact O-N 3.16Å; V299-E303 VanDerWaalsContact O-CB 3.26Å; V299-E303 WeakPolarHBondContact O-CB 3.25Å; V299-E303 PolarHBondContact O-N 3.47Å; V299-F469 HydrophobicContact CG2-CZ 4.06Å
300V96.5Very high91Very high0 Ų048.4 Ų48.40%023%0.23CC..Hα-helixtrans-61.7-43.5179.8176.70000112.1F254 V292 R295 H296 I297 E302 E303 I304F254-V300 HydrophobicContact CB-CG2 3.9Å; F254-V300 HydrophobicContact CD1-CG1 3.9Å; F254-V300 HydrophobicContact CD1-CG2 4.29Å; F254-V300 HydrophobicContact CD2-CG1 4.43Å; F254-V300 HydrophobicContact CE1-CG1 4Å; F254-V300 HydrophobicContact CG-CG1 4.12Å; F254-V300 HydrophobicContact CG-CG2 4.19Å; F254-V300 HydrophobicContact CZ-CG1 4.3Å; V292-V300 HydrophobicContact CB-CG1 4.29Å; V292-V300 HydrophobicContact CB-CG2 3.98Å; V292-V300 HydrophobicContact CG2-CG1 4.4Å; R295-V300 HydrophobicContact CB-CG2 3.85Å; H296-V300 PolarHBondContact O-N 3.44Å; H296-V300 VanDerWaalsContact O-N 3.11Å; I297-V300 HydrophobicContact CD1-CB 4.44Å; I297-V300 PolarHBondContact O-N 3.42Å; V300-E302 PolarHBondContact O-N 3.29Å; V300-E303 PolarHBondContact O-N 2.85Å; V300-I304 HydrophobicContact CG1-CD1 3.45Å; V300-I304 VanDerWaalsContact CG1-CD1 3.45Å; V300-I304 HydrophobicContact CG1-CG1 4.02Å; V300-I304 PolarHBondContact O-N 2.84Å
301L93.9Very high89.8Confident60 Ų6047.2 Ų47.231%0.31422%0.222SC..Hα-helixtrans-62.2-26.6177.1-71.9167.1000113.1I297 V299 P305 A351 M355I297-L301 HydrophobicContact CD1-CG 4.37Å; I297-L301 HydrophobicContact CG1-CD1 4.19Å; I297-L301 HydrophobicContact CG1-CG 4.34Å; I297-L301 VanDerWaalsContact O-CG 3.3Å; I297-L301 WeakPolarHBondContact O-CG 3.1Å; I297-L301 PolarHBondContact O-N 3.26Å; V299-L301 PolarHBondContact O-N 3.23Å; L301-P305 WeakPolarHBondContact O-CD 3.32Å; L301-P305 VanDerWaalsContact O-CG 3.26Å; L301-P305 WeakPolarHBondContact O-CG 3.5Å; L301-A351 HydrophobicContact CD2-CB 3.95Å; L301-M355 HydrophobicContact CD1-CE 4.43Å; L301-M355 HydrophobicContact CD1-CG 3.69Å; L301-M355 HydrophobicContact CD1-SD 3.88Å; L301-M355 HydrophobicContact CD2-CG 4.23Å; L301-M355 HydrophobicContact CG-CG 4.44Å
302E92.6Very high88.6Confident114 Ų11442.1 Ų42.153%0.53321%0.205SC..Hα-helixtrans-85.6-39.3172.3-69.7-170.3-165.400112.9A298 V299 V300 K306A298-E302 PolarHBondContact O-N 3.35Å; V299-E302 PolarHBondContact O-N 3Å; V299-E302 VanDerWaalsContact O-N 3.16Å; V300-E302 PolarHBondContact O-N 3.29Å; E302-K306 WeakPolarHBondContact O-CD 3.31Å; E302-K306 WeakPolarHBondContact O-CG 3.46Å; E302-K306 PolarHBondContact O-N 3.01Å; E302-K306 IonicContact OE2-NZ 2.79Å; E302-K306 PolarHBondContact OE2-NZ 3.22Å
303E91Very high87.1Confident15 Ų1546.1 Ų46.17%0.0723%0.233CC..Hα-helixtrans-74-42.4-170.3-173.5164.9-178.400112.4R291 R295 V299 V300 K306 L307R291-E303 IonicContact CZ-OE1 3.12Å; R291-E303 IonicContact NE-OE1 3.72Å; R291-E303 PolarHBondContact NE-OE1 2.9Å; R291-E303 IonicContact NH2-OE1 3.13Å; R291-E303 PolarHBondContact NH2-OE1 3.02Å; R295-E303 WeakPolarHBondContact CD-OE2 3.43Å; R295-E303 IonicContact CZ-OE1 3.99Å; R295-E303 IonicContact CZ-OE2 3.86Å; R295-E303 IonicContact NE-OE2 3.92Å; R295-E303 PolarHBondContact NE-OE2 3.33Å; R295-E303 IonicContact NH1-OE1 3.33Å; R295-E303 IonicContact NH1-OE2 2.91Å; R295-E303 PolarHBondContact NH1-OE2 3Å; V299-E303 VanDerWaalsContact O-CB 3.26Å; V299-E303 WeakPolarHBondContact O-CB 3.25Å; V299-E303 PolarHBondContact O-N 3.47Å; V300-E303 PolarHBondContact O-N 2.85Å; E303-K306 PolarHBondContact O-N 2.82Å; E303-K306 VanDerWaalsContact O-N 3.15Å; E303-L307 HydrophobicContact CG-CD1 4.06Å; E303-L307 HydrophobicContact CG-CG 4.41Å; E303-L307 WeakPolarHBondContact O-CG 3.19Å; E303-L307 PolarHBondContact O-N 3.03Å
304I89.2Confident85.3Confident0 Ų050.7 Ų50.70%026%0.261CS..Hα-helixtrans-58.8-50.4179.3-67.5172.1000111.1V300 K306 L307 M308 H347 L348V300-I304 HydrophobicContact CG1-CD1 3.45Å; V300-I304 VanDerWaalsContact CG1-CD1 3.45Å; V300-I304 HydrophobicContact CG1-CG1 4.02Å; V300-I304 PolarHBondContact O-N 2.84Å; I304-K306 PolarHBondContact O-N 2.91Å; I304-L307 PolarHBondContact O-N 3.24Å; I304-M308 PolarHBondContact O-N 2.58Å; I304-H347 HydrophobicContact CD1-CB 3.7Å; I304-L348 HydrophobicContact CG2-CB 4.27Å; I304-L348 HydrophobicContact CG2-CD1 4.42Å
305P85.5Confident83.1Confident25 Ų2556.8 Ų56.816%0.16229%0.287CS..Hα-helixtrans-56.6-41.3171.1-33.741.3000115.4L301 M308 K309 T322L301-P305 WeakPolarHBondContact O-CD 3.32Å; L301-P305 VanDerWaalsContact O-CG 3.26Å; L301-P305 WeakPolarHBondContact O-CG 3.5Å; P305-M308 WeakPolarHBondContact O-CB 3.36Å; P305-M308 PolarHBondContact O-N 3.5Å; P305-K309 PolarHBondContact O-N 3.16Å; P305-K309 VanDerWaalsContact O-N 3.11Å; P305-T322 WeakPolarHBondContact CB-OG1 3.45Å
306K87.2Confident80.8Confident111 Ų11161.7 Ų61.748%0.48331%0.312SS..Hα-helixtrans-62.8-45.8-179.9-75.1169.2-168.2168.60110.9E302 E303 I304 M308 K309 E310E302-K306 WeakPolarHBondContact O-CD 3.31Å; E302-K306 WeakPolarHBondContact O-CG 3.46Å; E302-K306 PolarHBondContact O-N 3.01Å; E302-K306 IonicContact OE2-NZ 2.79Å; E302-K306 PolarHBondContact OE2-NZ 3.22Å; E303-K306 PolarHBondContact O-N 2.82Å; E303-K306 VanDerWaalsContact O-N 3.15Å; I304-K306 PolarHBondContact O-N 2.91Å; K306-M308 PolarHBondContact O-N 3.18Å; K306-K309 WeakPolarHBondContact O-CB 3.38Å; K306-K309 PolarHBondContact O-N 3.15Å; K306-K309 VanDerWaalsContact O-N 3.1Å; K306-E310 PolarHBondContact O-N 3Å; K306-E310 VanDerWaalsContact O-N 3.15Å
307L82.1Confident78.6Confident19 Ų1962.6 Ų62.610%0.09932%0.324CS..Hα-helixtrans-62.3-32.3176.5-67.7170.8000112.9L288 E303 I304 E310 I311L288-L307 HydrophobicContact CD1-CD1 3.62Å; E303-L307 HydrophobicContact CG-CD1 4.06Å; E303-L307 HydrophobicContact CG-CG 4.41Å; E303-L307 WeakPolarHBondContact O-CG 3.19Å; E303-L307 PolarHBondContact O-N 3.03Å; I304-L307 PolarHBondContact O-N 3.24Å; L307-E310 PolarHBondContact O-N 3.03Å; L307-I311 WeakPolarHBondContact O-CG1 3.37Å; L307-I311 PolarHBondContact O-N 2.86Å
308M73.9Confident76.5Confident5 Ų567.7 Ų67.73%0.02536%0.355CS..Hα-helixtrans-68.2-39.7174.7-169.3-165.9-45.400112.3I304 P305 K306 E310 I311 S312 T322 L327I304-M308 PolarHBondContact O-N 2.58Å; P305-M308 WeakPolarHBondContact O-CB 3.36Å; P305-M308 PolarHBondContact O-N 3.5Å; K306-M308 PolarHBondContact O-N 3.18Å; M308-E310 VanDerWaalsContact C-N 3.28Å; M308-E310 PolarHBondContact O-N 3.34Å; M308-I311 PolarHBondContact O-N 3Å; M308-S312 PolarHBondContact O-N 3.11Å; M308-S312 VanDerWaalsContact O-N 3.16Å; M308-S312 PolarHBondContact O-OG 3.04Å; M308-T322 HydrophobicContact CB-CG2 4.25Å; M308-T322 HydrophobicContact CE-CG2 3.96Å; M308-T322 HydrophobicContact CG-CG2 4.2Å; M308-T322 VanDerWaalsContact SD-CB 3.53Å; M308-T322 HydrophobicContact SD-CG2 3.31Å; M308-T322 WeakPolarHBondContact SD-CG2 3.21Å; M308-L327 HydrophobicContact CE-CD1 3.5Å; M308-L327 VanDerWaalsContact CE-CD1 3.5Å; M308-L327 HydrophobicContact CE-CD2 3.45Å; M308-L327 VanDerWaalsContact CE-CD2 3.45Å; M308-L327 HydrophobicContact CE-CG 3.55Å; M308-L327 HydrophobicContact CG-CD2 3.81Å; M308-L327 HydrophobicContact SD-CD1 4.2Å; M308-L327 HydrophobicContact SD-CD2 3.22Å; M308-L327 WeakPolarHBondContact SD-CD2 3.25Å; M308-L327 HydrophobicContact SD-CG 3.53Å; M308-L327 VanDerWaalsContact SD-CG 3.53Å
309K77.9Confident74.2Confident118 Ų11875.8 Ų75.851%0.51339%0.386SS..Hα-helixtrans-63.2-34.2174.4-71.8-177.5-179.7-179.20112P305 K306 S312 S313 T322P305-K309 PolarHBondContact O-N 3.16Å; P305-K309 VanDerWaalsContact O-N 3.11Å; K306-K309 WeakPolarHBondContact O-CB 3.38Å; K306-K309 PolarHBondContact O-N 3.15Å; K306-K309 VanDerWaalsContact O-N 3.1Å; K309-S312 VanDerWaalsContact CA-OG 3.31Å; K309-S312 WeakPolarHBondContact CA-OG 3.28Å; K309-S312 PolarHBondContact O-N 3.04Å; K309-S312 PolarHBondContact O-OG 2.84Å; K309-S313 VanDerWaalsContact O-CB 3.24Å; K309-S313 WeakPolarHBondContact O-CB 3.45Å; K309-S313 PolarHBondContact O-N 2.67Å; K309-S313 PolarHBondContact O-OG 3.35Å; K309-T322 HydrophobicContact CG-CG2 4.23Å
310E77.3Confident72Confident113 Ų11375.3 Ų75.353%0.52839%0.392SS..Hα-helixtrans-66.1-40.8175.4-68.7171.8-168.300112.5K306 L307 M308 S312 S313 T314K306-E310 PolarHBondContact O-N 3Å; K306-E310 VanDerWaalsContact O-N 3.15Å; L307-E310 PolarHBondContact O-N 3.03Å; M308-E310 VanDerWaalsContact C-N 3.28Å; M308-E310 PolarHBondContact O-N 3.34Å; E310-S312 VanDerWaalsContact C-N 3.3Å; E310-S312 PolarHBondContact O-N 3.18Å; E310-S313 PolarHBondContact O-OG 2.86Å; E310-T314 PolarHBondContact O-N 3.23Å; E310-T314 PolarHBondContact O-OG1 3.47Å
311I71.2Confident70Confident23 Ų2384.8 Ų84.812%0.11843%0.433CS..Hα-helixtrans-63.8-38.4175.6-64.1173.3000110.9L307 M308 F337 Q340 Q344L307-I311 WeakPolarHBondContact O-CG1 3.37Å; L307-I311 PolarHBondContact O-N 2.86Å; M308-I311 PolarHBondContact O-N 3Å; I311-F337 HydrophobicContact CG2-CB 4.19Å; I311-F337 HydrophobicContact CG2-CD1 3.97Å; I311-F337 HydrophobicContact CG2-CD2 4.42Å; I311-F337 HydrophobicContact CG2-CE1 4.47Å; I311-F337 HydrophobicContact CG2-CG 3.94Å; I311-Q340 HydrophobicContact CD1-CB 4.17Å; I311-Q344 VanDerWaalsContact CD1-NE2 3.28Å
312S67.1Low68.5Low14 Ų1483.8 Ų83.810%0.09843%0.43CS..Hα-helixtrans-81.9-33.4-178.137.30000113.7M308 K309 E310 T314 K315M308-S312 PolarHBondContact O-N 3.11Å; M308-S312 VanDerWaalsContact O-N 3.16Å; M308-S312 PolarHBondContact O-OG 3.04Å; K309-S312 VanDerWaalsContact CA-OG 3.31Å; K309-S312 WeakPolarHBondContact CA-OG 3.28Å; K309-S312 PolarHBondContact O-N 3.04Å; K309-S312 PolarHBondContact O-OG 2.84Å; E310-S312 VanDerWaalsContact C-N 3.3Å; E310-S312 PolarHBondContact O-N 3.18Å; S312-T314 VanDerWaalsContact C-N 3.28Å; S312-T314 PolarHBondContact O-N 3.2Å; S312-K315 CarbonylContact O-C 3.58Å; S312-K315 VanDerWaalsContact O-C 3.29Å; S312-K315 PolarHBondContact O-N 3.17Å; S312-K315 VanDerWaalsContact O-N 3.15Å
313S64Low67.4Low84 Ų8480.7 Ų80.759%0.58742%0.421SS*.Hα-helixtrans-68.9-25.8176.368.60000113K309 E310 K315 K316K309-S313 VanDerWaalsContact O-CB 3.24Å; K309-S313 WeakPolarHBondContact O-CB 3.45Å; K309-S313 PolarHBondContact O-N 2.67Å; K309-S313 PolarHBondContact O-OG 3.35Å; E310-S313 PolarHBondContact O-OG 2.86Å; S313-K315 PolarHBondContact O-N 2.93Å; S313-K316 PolarHBondContact O-N 2.78Å
314T60Low66.5Low100 Ų10081.6 Ų81.661%0.61343%0.426SS*.THydrogen-bonded Turntrans-54.3-19.8170.8-56.10000112E310 S312E310-T314 PolarHBondContact O-N 3.23Å; E310-T314 PolarHBondContact O-OG1 3.47Å; S312-T314 VanDerWaalsContact C-N 3.28Å; S312-T314 PolarHBondContact O-N 3.2Å
315K50.9Low65.9Low159 Ų15984.9 Ų84.969%0.69145%0.449SS*.THydrogen-bonded Turntrans-144.977.2164.4-67.2-168.2178-176.10112.7S312 S313 A317S312-K315 CarbonylContact O-C 3.58Å; S312-K315 VanDerWaalsContact O-C 3.29Å; S312-K315 PolarHBondContact O-N 3.17Å; S312-K315 VanDerWaalsContact O-N 3.15Å; S313-K315 PolarHBondContact O-N 2.93Å; K315-A317 VanDerWaalsContact O-CB 3.26Å; K315-A317 WeakPolarHBondContact O-CB 3.36Å; K315-A317 PolarHBondContact O-N 3.01Å
316K50.3Low65.4Low213 Ų21385.6 Ų85.693%0.92646%0.457SS*.THydrogen-bonded Turntrans23.249.7160.9-76.3-169175.9-177.30116.8S313S313-K316 PolarHBondContact O-N 2.78Å
317A51.7Low64.5Low46 Ų4680.3 Ų80.338%0.3843%0.434SS..  trans-137.2110.9-178.200000110.4K315K315-A317 VanDerWaalsContact O-CB 3.26Å; K315-A317 WeakPolarHBondContact O-CB 3.36Å; K315-A317 PolarHBondContact O-N 3.01Å
318T52.3Low64.1Low112 Ų11280.7 Ų80.769%0.68744%0.437SS*.  trans85.592.1162.3-8.30000116.6G320T318-G320 PolarHBondContact O-N 3.32Å
319E47.1Very low64.2Low208 Ų20886.2 Ų86.297%0.97246%0.463SS*.  trans-73.6103.1152.9-71.2179.5172.500108.3
320G50Low63.9Low42 Ų4281.5 Ų81.543%0.43344%0.443SS..SBendtrans-164155.4176.200000111.1T318 T322T318-G320 PolarHBondContact O-N 3.32Å; G320-T322 PolarHBondContact O-N 3.46Å
321K54.4Low63.5Low200 Ų20077.9 Ų77.987%0.8743%0.427SS*.  trans-57.1129.4169.5-76.9-177.7177.8179.20108.4S323K321-S323 PolarHBondContact O-N 3.13Å
322T63.1Low63.7Low39 Ų3985.1 Ų85.124%0.23946%0.457CS..  trans-71.195.3177.445.80000109.2P305 M308 K309 G320P305-T322 WeakPolarHBondContact CB-OG1 3.45Å; M308-T322 HydrophobicContact CB-CG2 4.25Å; M308-T322 HydrophobicContact CE-CG2 3.96Å; M308-T322 HydrophobicContact CG-CG2 4.2Å; M308-T322 VanDerWaalsContact SD-CB 3.53Å; M308-T322 HydrophobicContact SD-CG2 3.31Å; M308-T322 WeakPolarHBondContact SD-CG2 3.21Å; K309-T322 HydrophobicContact CG-CG2 4.23Å; G320-T322 PolarHBondContact O-N 3.46Å
323S68.6Low64.1Low48 Ų4892.2 Ų92.234%0.33649%0.486SS..  trans-98.6157.7172.165.70000111K321 S325 A326 L327K321-S323 PolarHBondContact O-N 3.13Å; S323-S325 PolarHBondContact O-N 3.01Å; S323-S325 PolarHBondContact OG-OG 3.33Å; S323-A326 WeakPolarHBondContact O-CB 3.33Å; S323-A326 PolarHBondContact O-N 2.58Å; S323-A326 WeakPolarHBondContact OG-CB 3.36Å; S323-A326 PolarHBondContact OG-N 3.22Å; S323-A326 VanDerWaalsContact OG-N 3.15Å; S323-L327 PolarHBondContact O-N 2.87Å
324L73.6Confident64.7Low34 Ų3489.8 Ų89.818%0.17847%0.466CS..Hα-helixtrans-56.2-35.7173.7-172.963000112.6T273 L327 T328 V345 N349T273-L324 HydrophobicContact CG2-CD1 4.28Å; T273-L324 HydrophobicContact CG2-CD2 4.13Å; T273-L324 HydrophobicContact CG2-CG 4.22Å; L324-L327 HydrophobicContact CD1-CD1 4.44Å; L324-L327 WeakPolarHBondContact O-CB 3.41Å; L324-L327 PolarHBondContact O-N 2.95Å; L324-T328 PolarHBondContact O-N 3.09Å; L324-T328 VanDerWaalsContact O-N 3.13Å; L324-T328 PolarHBondContact O-OG1 3.33Å; L324-V345 HydrophobicContact CD1-CB 4.48Å; L324-V345 HydrophobicContact CD1-CG1 3.84Å; L324-V345 HydrophobicContact CD1-CG2 4.32Å; L324-N349 VanDerWaalsContact CD1-ND2 3.28Å; L324-N349 WeakPolarHBondContact CD1-ND2 3.43Å
325S75.7Confident65.5Low70 Ų7089.1 Ų89.149%0.4946%0.463SS..Hα-helixtrans-67.5-40.117557.50000112.9S323 L327 T328 Q329S323-S325 PolarHBondContact O-N 3.01Å; S323-S325 PolarHBondContact OG-OG 3.33Å; S325-L327 VanDerWaalsContact C-N 3.3Å; S325-L327 PolarHBondContact O-N 2.67Å; S325-T328 PolarHBondContact O-N 2.69Å; S325-Q329 WeakPolarHBondContact O-CG 3.26Å; S325-Q329 PolarHBondContact O-N 2.69Å; S325-Q329 VanDerWaalsContact O-N 3.16Å
326A74.5Confident66.8Low39 Ų3990 Ų9032%0.32247%0.47SS..Hα-helixtrans-64.6-37.9175.600000111S323 Q329 L330S323-A326 WeakPolarHBondContact O-CB 3.33Å; S323-A326 PolarHBondContact O-N 2.58Å; S323-A326 WeakPolarHBondContact OG-CB 3.36Å; S323-A326 PolarHBondContact OG-N 3.22Å; S323-A326 VanDerWaalsContact OG-N 3.15Å; A326-Q329 PolarHBondContact O-N 3.09Å; A326-L330 WeakPolarHBondContact O-CB 3.28Å; A326-L330 PolarHBondContact O-N 3.18Å
327L68.8Low68.3Low0 Ų083 Ų830%044%0.439CS..Hα-helixtrans-59.9-51174.7-85.5172.6000112.6M308 S323 L324 S325 Q329 L330 M331 I341 V345 L348M308-L327 HydrophobicContact CE-CD1 3.5Å; M308-L327 VanDerWaalsContact CE-CD1 3.5Å; M308-L327 HydrophobicContact CE-CD2 3.45Å; M308-L327 VanDerWaalsContact CE-CD2 3.45Å; M308-L327 HydrophobicContact CE-CG 3.55Å; M308-L327 HydrophobicContact CG-CD2 3.81Å; M308-L327 HydrophobicContact SD-CD1 4.2Å; M308-L327 HydrophobicContact SD-CD2 3.22Å; M308-L327 WeakPolarHBondContact SD-CD2 3.25Å; M308-L327 HydrophobicContact SD-CG 3.53Å; M308-L327 VanDerWaalsContact SD-CG 3.53Å; S323-L327 PolarHBondContact O-N 2.87Å; L324-L327 HydrophobicContact CD1-CD1 4.44Å; L324-L327 WeakPolarHBondContact O-CB 3.41Å; L324-L327 PolarHBondContact O-N 2.95Å; S325-L327 VanDerWaalsContact C-N 3.3Å; S325-L327 PolarHBondContact O-N 2.67Å; L327-Q329 PolarHBondContact O-N 3.22Å; L327-L330 WeakPolarHBondContact O-CB 3.44Å; L327-L330 PolarHBondContact O-N 2.87Å; L327-L330 VanDerWaalsContact O-N 3.11Å; L327-M331 WeakPolarHBondContact O-CG 3.43Å; L327-M331 PolarHBondContact O-N 3.17Å; L327-I341 HydrophobicContact CD2-CG2 3.72Å; L327-V345 HydrophobicContact CB-CG2 3.83Å; L327-V345 HydrophobicContact CD1-CG2 3.81Å; L327-V345 HydrophobicContact CD2-CG2 4.38Å; L327-V345 HydrophobicContact CG-CG2 4.27Å; L327-L348 HydrophobicContact CD1-CD2 3.71Å
328T74.3Confident69.7Low28 Ų2888.2 Ų88.217%0.17245%0.449CS..Hα-helixtrans-60.1-36.5177.5-59.90000111.8D274 L324 S325D274-T328 WeakPolarHBondContact OD2-CG2 3.11Å; D274-T328 PolarHBondContact OD2-OG1 3.14Å; L324-T328 PolarHBondContact O-N 3.09Å; L324-T328 VanDerWaalsContact O-N 3.13Å; L324-T328 PolarHBondContact O-OG1 3.33Å; S325-T328 PolarHBondContact O-N 2.69Å
329Q76.1Confident71.3Confident120 Ų12090.2 Ų90.256%0.56145%0.448SS*.Hα-helixtrans-69-39.8174.5-70.6-179.61.900112.5S325 A326 L327 M331 K332 K333S325-Q329 WeakPolarHBondContact O-CG 3.26Å; S325-Q329 PolarHBondContact O-N 2.69Å; S325-Q329 VanDerWaalsContact O-N 3.16Å; A326-Q329 PolarHBondContact O-N 3.09Å; L327-Q329 PolarHBondContact O-N 3.22Å; Q329-M331 VanDerWaalsContact C-N 3.31Å; Q329-M331 PolarHBondContact O-N 2.98Å; Q329-K332 WeakPolarHBondContact O-CB 3.1Å; Q329-K332 PolarHBondContact O-N 2.85Å; Q329-K332 VanDerWaalsContact O-N 3.16Å; Q329-K333 PolarHBondContact O-N 3.45Å
330L71.6Confident73Confident20 Ų2085 Ų8511%0.10542%0.424CS..Hα-helixtrans-61.2-40.2176.7-160.372.8000111.3A326 L327 K332 K333 M334 I341A326-L330 WeakPolarHBondContact O-CB 3.28Å; A326-L330 PolarHBondContact O-N 3.18Å; L327-L330 WeakPolarHBondContact O-CB 3.44Å; L327-L330 PolarHBondContact O-N 2.87Å; L327-L330 VanDerWaalsContact O-N 3.11Å; L330-K332 VanDerWaalsContact C-N 3.27Å; L330-K332 PolarHBondContact O-N 2.55Å; L330-K333 PolarHBondContact O-N 3.26Å; L330-K333 VanDerWaalsContact O-N 3.11Å; L330-M334 HydrophobicContact CD1-CE 3.32Å; L330-M334 HydrophobicContact CD2-CE 3.73Å; L330-M334 HydrophobicContact CG-CE 3.36Å; L330-M334 PolarHBondContact O-N 3.18Å; L330-I341 HydrophobicContact CB-CD1 4.41Å; L330-I341 HydrophobicContact CD2-CD1 4.03Å; L330-I341 HydrophobicContact CD2-CG1 4.48Å; L330-I341 HydrophobicContact CG-CD1 4.1Å
331M68.4Low74.6Confident37 Ų3783 Ų8318%0.18240%0.404CS..Hα-helixtrans-57.3-38.6174.3-68.7-177.770.400112.9L327 Q329 R338 I341 S342L327-M331 WeakPolarHBondContact O-CG 3.43Å; L327-M331 PolarHBondContact O-N 3.17Å; Q329-M331 VanDerWaalsContact C-N 3.31Å; Q329-M331 PolarHBondContact O-N 2.98Å; M331-R338 HydrophobicContact CE-CG 3.59Å; M331-I341 HydrophobicContact CB-CG2 4.5Å; M331-I341 HydrophobicContact CG-CB 3.76Å; M331-I341 HydrophobicContact CG-CD1 4.37Å; M331-I341 HydrophobicContact CG-CG2 3.23Å; M331-I341 HydrophobicContact SD-CG2 4.1Å; M331-S342 WeakPolarHBondContact CE-OG 3.38Å
332K75.9Confident76.2Confident175 Ų17575.6 Ų75.676%0.76138%0.377SS*.Hα-helixtrans-69.3-34.7177.8-68.1-179.9179.4179.30111.9Q329 L330Q329-K332 WeakPolarHBondContact O-CB 3.1Å; Q329-K332 PolarHBondContact O-N 2.85Å; Q329-K332 VanDerWaalsContact O-N 3.16Å; L330-K332 VanDerWaalsContact C-N 3.27Å; L330-K332 PolarHBondContact O-N 2.55Å
333K75.6Confident77.5Confident163 Ų16375.8 Ų75.871%0.70937%0.374SS*.Hα-helixtrans-82.6-27.5-178.7-68.7-176179.3179.90113.7Q329 L330Q329-K333 PolarHBondContact O-N 3.45Å; L330-K333 PolarHBondContact O-N 3.26Å; L330-K333 VanDerWaalsContact O-N 3.11Å
334M76.3Confident78.5Confident32 Ų3273.9 Ų73.916%0.15836%0.36CS..  trans-127.277.6-175-70.8-164.4-71.800112.2L330 H336 F337 R338L330-M334 HydrophobicContact CD1-CE 3.32Å; L330-M334 HydrophobicContact CD2-CE 3.73Å; L330-M334 HydrophobicContact CG-CE 3.36Å; L330-M334 PolarHBondContact O-N 3.18Å; M334-H336 VanDerWaalsContact C-N 3.26Å; M334-H336 PolarHBondContact O-N 3.21Å; M334-F337 HydrophobicContact CB-CB 4.49Å; M334-F337 HydrophobicContact CB-CD2 4.31Å; M334-F337 PolarHBondContact O-N 3.24Å; M334-F337 VanDerWaalsContact O-N 3.17Å; M334-F337 HydrophobicContact SD-CD2 4.08Å; M334-R338 PolarHBondContact O-N 2.79Å
335P76.5Confident79.3Confident86 Ų8672.5 Ų72.556%0.55835%0.353SS*.G310 helixtrans-62.8-30.7-177.524.1-33.5000113.1F337 R338P335-F337 VanDerWaalsContact C-N 3.27Å; P335-F337 PolarHBondContact O-N 3.24Å; P335-R338 WeakPolarHBondContact O-CB 3.37Å; P335-R338 PolarHBondContact O-N 2.99Å
336H78.8Confident80.2Confident179 Ų17969.8 Ų69.883%0.82933%0.334SS*.G310 helixtrans-63.3-30.7177.6-60.8-68.5000113.3M334M334-H336 VanDerWaalsContact C-N 3.26Å; M334-H336 PolarHBondContact O-N 3.21Å
337F80Confident81.2Confident65 Ų6568 Ų6829%0.28532%0.318SS..G310 helixtrans-96.75178.9-68.7-73000113.1I311 M334 P335 K339 Q340 I341I311-F337 HydrophobicContact CG2-CB 4.19Å; I311-F337 HydrophobicContact CG2-CD1 3.97Å; I311-F337 HydrophobicContact CG2-CD2 4.42Å; I311-F337 HydrophobicContact CG2-CE1 4.47Å; I311-F337 HydrophobicContact CG2-CG 3.94Å; M334-F337 HydrophobicContact CB-CB 4.49Å; M334-F337 HydrophobicContact CB-CD2 4.31Å; M334-F337 PolarHBondContact O-N 3.24Å; M334-F337 VanDerWaalsContact O-N 3.17Å; M334-F337 HydrophobicContact SD-CD2 4.08Å; P335-F337 VanDerWaalsContact C-N 3.27Å; P335-F337 PolarHBondContact O-N 3.24Å; F337-K339 VanDerWaalsContact C-N 3.28Å; F337-K339 PolarHBondContact O-N 2.97Å; F337-K339 VanDerWaalsContact O-N 3.15Å; F337-Q340 PolarHBondContact O-N 3.19Å; F337-I341 HydrophobicContact CB-CD1 3.93Å; F337-I341 HydrophobicContact CB-CG1 4.22Å; F337-I341 WeakPolarHBondContact O-CG1 2.88Å; F337-I341 PolarHBondContact O-N 2.96Å
338R82.2Confident82.4Confident156 Ų15668.5 Ų68.559%0.58932%0.321SS*.Hα-helixtrans-53.2-41.6-173.1-172.6-179.4179.5-172-0.5113.1M331 M334 P335 I341 S342M331-R338 HydrophobicContact CE-CG 3.59Å; M334-R338 PolarHBondContact O-N 2.79Å; P335-R338 WeakPolarHBondContact O-CB 3.37Å; P335-R338 PolarHBondContact O-N 2.99Å; R338-I341 PolarHBondContact O-N 2.81Å; R338-S342 WeakPolarHBondContact O-CB 3.27Å; R338-S342 PolarHBondContact O-N 3.01Å; R338-S342 PolarHBondContact O-OG 3.38Å
339K85Confident83.3Confident154 Ų15467.6 Ų67.667%0.6732%0.315SS*.Hα-helixtrans-63-44.7179-171.9-179.4-179.4-176.30112.1F337 K343F337-K339 VanDerWaalsContact C-N 3.28Å; F337-K339 PolarHBondContact O-N 2.97Å; F337-K339 VanDerWaalsContact O-N 3.15Å; K339-K343 WeakPolarHBondContact O-CG 3.07Å; K339-K343 PolarHBondContact O-N 3.01Å
340Q83.8Confident84.4Confident99 Ų9961.9 Ų61.946%0.46329%0.288SS..Hα-helixtrans-67.8-43.3178.4-69179.8-6.100111.3I311 F337 S342 K343 Q344I311-Q340 HydrophobicContact CD1-CB 4.17Å; F337-Q340 PolarHBondContact O-N 3.19Å; Q340-S342 PolarHBondContact O-N 2.72Å; Q340-K343 PolarHBondContact O-N 3.33Å; Q340-Q344 PolarHBondContact O-N 2.78Å
341I84.1Confident85.6Confident0 Ų060.9 Ų60.90%028%0.283CS..Hα-helixtrans-64.2-41.2178.1-59167.5000110.6L327 L330 M331 F337 R338 K343 Q344 V345L327-I341 HydrophobicContact CD2-CG2 3.72Å; L330-I341 HydrophobicContact CB-CD1 4.41Å; L330-I341 HydrophobicContact CD2-CD1 4.03Å; L330-I341 HydrophobicContact CD2-CG1 4.48Å; L330-I341 HydrophobicContact CG-CD1 4.1Å; M331-I341 HydrophobicContact CB-CG2 4.5Å; M331-I341 HydrophobicContact CG-CB 3.76Å; M331-I341 HydrophobicContact CG-CD1 4.37Å; M331-I341 HydrophobicContact CG-CG2 3.23Å; M331-I341 HydrophobicContact SD-CG2 4.1Å; F337-I341 HydrophobicContact CB-CD1 3.93Å; F337-I341 HydrophobicContact CB-CG1 4.22Å; F337-I341 WeakPolarHBondContact O-CG1 2.88Å; F337-I341 PolarHBondContact O-N 2.96Å; R338-I341 PolarHBondContact O-N 2.81Å; I341-K343 VanDerWaalsContact C-N 3.34Å; I341-K343 PolarHBondContact O-N 3.12Å; I341-Q344 PolarHBondContact O-N 3.11Å; I341-V345 WeakPolarHBondContact O-CG2 3.49Å; I341-V345 PolarHBondContact O-N 2.92Å
342S88.3Confident86.8Confident44 Ų4463 Ų6331%0.30829%0.292SS..Hα-helixtrans-57.7-44.1174.1-69.30000112.4M331 R338 Q340 V345 V346M331-S342 WeakPolarHBondContact CE-OG 3.38Å; R338-S342 WeakPolarHBondContact O-CB 3.27Å; R338-S342 PolarHBondContact O-N 3.01Å; R338-S342 PolarHBondContact O-OG 3.38Å; Q340-S342 PolarHBondContact O-N 2.72Å; S342-V345 WeakPolarHBondContact O-CB 3.24Å; S342-V345 PolarHBondContact O-N 2.97Å; S342-V346 WeakPolarHBondContact O-CG2 3.4Å; S342-V346 PolarHBondContact O-N 3.48Å; S342-V346 VanDerWaalsContact O-N 3.09Å
343K90Very high87.8Confident42 Ų4257.1 Ų57.118%0.18327%0.27CS..Hα-helixtrans-62.7-44.1176.8-72.2171.3153.6-159.40111.5D285 D286 K339 Q340 I341 V345 V346 H347D285-K343 PolarHBondContact O-NZ 2.94Å; D286-K343 VanDerWaalsContact OD1-CD 3.23Å; D286-K343 WeakPolarHBondContact OD1-CD 3.41Å; D286-K343 WeakPolarHBondContact OD1-CE 3.21Å; D286-K343 IonicContact OD1-NZ 2.99Å; D286-K343 PolarHBondContact OD1-NZ 2.83Å; D286-K343 WeakPolarHBondContact OD2-CG 3.36Å; K339-K343 WeakPolarHBondContact O-CG 3.07Å; K339-K343 PolarHBondContact O-N 3.01Å; Q340-K343 PolarHBondContact O-N 3.33Å; I341-K343 VanDerWaalsContact C-N 3.34Å; I341-K343 PolarHBondContact O-N 3.12Å; K343-V345 VanDerWaalsContact C-N 3.34Å; K343-V345 PolarHBondContact O-N 2.85Å; K343-V346 WeakPolarHBondContact O-CB 3.47Å; K343-V346 PolarHBondContact O-N 2.7Å; K343-H347 PolarHBondContact O-CD2 2.75Å; K343-H347 PolarHBondContact O-N 2.84Å; K343-H347 VanDerWaalsContact O-N 3.07Å
344Q89.7Confident88.9Confident9 Ų949.4 Ų49.44%0.04224%0.236CC..Hα-helixtrans-60.9-41.2175-74.8179.9-13.900112.8L288 I311 Q340 I341 V346 H347 L348L288-Q344 HydrophobicContact CD2-CB 4.34Å; L288-Q344 HydrophobicContact CD2-CG 3.6Å; I311-Q344 VanDerWaalsContact CD1-NE2 3.28Å; Q340-Q344 PolarHBondContact O-N 2.78Å; I341-Q344 PolarHBondContact O-N 3.11Å; Q344-V346 VanDerWaalsContact C-N 3.34Å; Q344-V346 PolarHBondContact O-N 2.63Å; Q344-H347 PolarHBondContact O-N 2.88Å; Q344-L348 VanDerWaalsContact O-CB 3.3Å; Q344-L348 WeakPolarHBondContact O-CB 3.1Å; Q344-L348 PolarHBondContact O-N 3.4Å
345V90.3Very high89.9Confident4 Ų449.1 Ų49.12%0.02424%0.235CC..Hα-helixtrans-57.5-47.8174.6164.30000110.5Y271 L324 L327 I341 S342 K343 L348 N349Y271-V345 HydrophobicContact CE2-CG1 4.31Å; L324-V345 HydrophobicContact CD1-CB 4.48Å; L324-V345 HydrophobicContact CD1-CG1 3.84Å; L324-V345 HydrophobicContact CD1-CG2 4.32Å; L327-V345 HydrophobicContact CB-CG2 3.83Å; L327-V345 HydrophobicContact CD1-CG2 3.81Å; L327-V345 HydrophobicContact CD2-CG2 4.38Å; L327-V345 HydrophobicContact CG-CG2 4.27Å; I341-V345 WeakPolarHBondContact O-CG2 3.49Å; I341-V345 PolarHBondContact O-N 2.92Å; S342-V345 WeakPolarHBondContact O-CB 3.24Å; S342-V345 PolarHBondContact O-N 2.97Å; K343-V345 VanDerWaalsContact C-N 3.34Å; K343-V345 PolarHBondContact O-N 2.85Å; V345-L348 PolarHBondContact O-N 3.49Å; V345-N349 PolarHBondContact O-N 2.88Å; V345-N349 PolarHBondContact O-ND2 2.99Å
346V94.2Very high90.8Very high14 Ų1449.2 Ų49.29%0.08523%0.231CC..Hα-helixtrans-56.6-54.5177.9171.60000110.7Y269 Y271 A280 S342 K343 Q344 L348 N349 L350Y269-V346 HydrophobicContact CD1-CG1 4.17Å; Y271-V346 HydrophobicContact CE1-CG2 3.95Å; Y271-V346 WeakPolarHBondContact OH-CG2 3.44Å; A280-V346 HydrophobicContact CB-CB 4.34Å; A280-V346 HydrophobicContact CB-CG1 3.59Å; A280-V346 HydrophobicContact CB-CG2 3.7Å; S342-V346 WeakPolarHBondContact O-CG2 3.4Å; S342-V346 PolarHBondContact O-N 3.48Å; S342-V346 VanDerWaalsContact O-N 3.09Å; K343-V346 WeakPolarHBondContact O-CB 3.47Å; K343-V346 PolarHBondContact O-N 2.7Å; Q344-V346 VanDerWaalsContact C-N 3.34Å; Q344-V346 PolarHBondContact O-N 2.63Å; V346-L348 VanDerWaalsContact C-N 3.32Å; V346-L348 PolarHBondContact O-N 3.28Å; V346-N349 PolarHBondContact O-N 3.33Å; V346-L350 WeakPolarHBondContact O-CB 2.83Å; V346-L350 PolarHBondContact O-N 2.68Å
347H95.3Very high91.5Very high1 Ų146.1 Ų46.11%0.00522%0.215CC..Hα-helixtrans-68.9-29.5-175.1-65.2-53.8000113.5F254 D286 L288 W289 I304 K343 Q344 A351F254-H347 HydrophobicContact CE1-CB 4.45Å; D286-H347 IonicContact OD2-CD2 3.48Å; D286-H347 IonicContact OD2-CE1 2.75Å; D286-H347 IonicContact OD2-NE2 3.33Å; D286-H347 PolarHBondContact OD2-NE2 3.17Å; L288-H347 HydrophobicContact CD2-CB 4.46Å; W289-H347 AromaticContact CE3-CE1 3.59Å; W289-H347 AromaticContact CE3-ND1 3.69Å; I304-H347 HydrophobicContact CD1-CB 3.7Å; K343-H347 PolarHBondContact O-CD2 2.75Å; K343-H347 PolarHBondContact O-N 2.84Å; K343-H347 VanDerWaalsContact O-N 3.07Å; Q344-H347 PolarHBondContact O-N 2.88Å; H347-A351 WeakPolarHBondContact O-CB 3.45Å; H347-A351 PolarHBondContact O-N 2.94Å
348L93.3Very high92.3Very high11 Ų1143.8 Ų43.86%0.05820%0.204CC..Hα-helixtrans-68.2-46.1172.9-174.165.5000111.4I304 L327 Q344 V345 V346 L350 A351 E352I304-L348 HydrophobicContact CG2-CB 4.27Å; I304-L348 HydrophobicContact CG2-CD1 4.42Å; L327-L348 HydrophobicContact CD1-CD2 3.71Å; Q344-L348 VanDerWaalsContact O-CB 3.3Å; Q344-L348 WeakPolarHBondContact O-CB 3.1Å; Q344-L348 PolarHBondContact O-N 3.4Å; V345-L348 PolarHBondContact O-N 3.49Å; V346-L348 VanDerWaalsContact C-N 3.32Å; V346-L348 PolarHBondContact O-N 3.28Å; L348-L350 VanDerWaalsContact C-N 3.31Å; L348-L350 PolarHBondContact O-N 3.37Å; L348-A351 PolarHBondContact O-N 3.06Å; L348-E352 WeakPolarHBondContact O-CB 3.44Å; L348-E352 WeakPolarHBondContact O-CG 3.15Å; L348-E352 PolarHBondContact O-N 3.3Å
349N95.1Very high92.8Very high8 Ų842.8 Ų42.84%0.04320%0.204CC..Hα-helixtrans-60.7-44174.7-78.2-92.5000110.6Y269 Y271 K272 L324 V345 V346 A351 E352 D353Y269-N349 HydrophobicContact CE1-CB 4.45Å; Y269-N349 PolarHBondContact OH-O 2.91Å; Y271-N349 HydrophobicContact CD2-CB 3.95Å; Y271-N349 HydrophobicContact CG-CB 4.36Å; K272-N349 PolarHBondContact O-OD1 3.05Å; L324-N349 VanDerWaalsContact CD1-ND2 3.28Å; L324-N349 WeakPolarHBondContact CD1-ND2 3.43Å; V345-N349 PolarHBondContact O-N 2.88Å; V345-N349 PolarHBondContact O-ND2 2.99Å; V346-N349 PolarHBondContact O-N 3.33Å; N349-A351 VanDerWaalsContact C-N 3.34Å; N349-A351 PolarHBondContact O-N 3.41Å; N349-E352 PolarHBondContact O-N 3.01Å; N349-D353 WeakPolarHBondContact O-CB 3.39Å; N349-D353 PolarHBondContact O-N 2.88Å
350L97.4Very high93Very high0 Ų041.7 Ų41.70%021%0.205CC..Hα-helixtrans-58.6-45.7178.2-175.165.2000111.5F254 A258 L262 I264 Y269 L282 W289 V346 L348 D353 C354F254-L350 HydrophobicContact CE1-CD2 4.16Å; F254-L350 HydrophobicContact CE2-CB 4.26Å; F254-L350 HydrophobicContact CE2-CD2 3.97Å; F254-L350 HydrophobicContact CE2-CG 3.79Å; F254-L350 HydrophobicContact CZ-CB 3.93Å; F254-L350 HydrophobicContact CZ-CD2 3.55Å; F254-L350 HydrophobicContact CZ-CG 3.72Å; A258-L350 HydrophobicContact CB-CD1 4.11Å; A258-L350 HydrophobicContact CB-CD2 4.42Å; A258-L350 HydrophobicContact CB-CG 4.37Å; L262-L350 HydrophobicContact CD1-CD1 3.48Å; L262-L350 VanDerWaalsContact CD1-CD1 3.48Å; I264-L350 HydrophobicContact CD1-CD1 4.37Å; Y269-L350 HydrophobicContact CD1-CB 4.22Å; Y269-L350 HydrophobicContact CD1-CD1 3.89Å; Y269-L350 HydrophobicContact CD2-CD1 3.66Å; Y269-L350 HydrophobicContact CE1-CB 3.68Å; Y269-L350 HydrophobicContact CE1-CD1 3.86Å; Y269-L350 HydrophobicContact CE1-CG 4.36Å; Y269-L350 HydrophobicContact CE2-CD1 3.67Å; Y269-L350 HydrophobicContact CG-CD1 3.78Å; Y269-L350 WeakPolarHBondContact OH-CA 3.4Å; Y269-L350 PolarHBondContact OH-N 2.74Å; L282-L350 HydrophobicContact CD1-CD2 4.15Å; L282-L350 HydrophobicContact CD2-CD2 4.04Å; W289-L350 HydrophobicContact CH2-CD2 4.33Å; W289-L350 HydrophobicContact CZ3-CD2 3.73Å; V346-L350 WeakPolarHBondContact O-CB 2.83Å; V346-L350 PolarHBondContact O-N 2.68Å; L348-L350 VanDerWaalsContact C-N 3.31Å; L348-L350 PolarHBondContact O-N 3.37Å; L350-D353 PolarHBondContact O-N 3.03Å; L350-C354 PolarHBondContact O-N 2.79Å; L350-C354 PolarHBondContact O-SG 3.39Å
351A97Very high93.1Very high0 Ų039.7 Ų39.70%020%0.198CC..Hα-helixtrans-65.5-41.6176.500000112.5F254 I297 L301 H347 L348 N349 C354 M355F254-A351 HydrophobicContact CE2-CB 3.92Å; F254-A351 HydrophobicContact CZ-CB 4.18Å; I297-A351 HydrophobicContact CD1-CB 3.97Å; L301-A351 HydrophobicContact CD2-CB 3.95Å; H347-A351 WeakPolarHBondContact O-CB 3.45Å; H347-A351 PolarHBondContact O-N 2.94Å; L348-A351 PolarHBondContact O-N 3.06Å; N349-A351 VanDerWaalsContact C-N 3.34Å; N349-A351 PolarHBondContact O-N 3.41Å; A351-C354 PolarHBondContact O-N 3.4Å; A351-M355 WeakPolarHBondContact O-CB 3.39Å; A351-M355 VanDerWaalsContact O-CG 3.3Å; A351-M355 WeakPolarHBondContact O-CG 3.41Å; A351-M355 PolarHBondContact O-N 2.87Å
352E95.2Very high93.5Very high80 Ų8040.3 Ų40.337%0.37420%0.201SC..Hα-helixtrans-63-43.9176.5-75.3179.2-179.800111.7L348 N349 M355 N356L348-E352 WeakPolarHBondContact O-CB 3.44Å; L348-E352 WeakPolarHBondContact O-CG 3.15Å; L348-E352 PolarHBondContact O-N 3.3Å; N349-E352 PolarHBondContact O-N 3.01Å; E352-M355 PolarHBondContact O-N 2.61Å; E352-N356 WeakPolarHBondContact O-CB 3.3Å; E352-N356 PolarHBondContact O-N 3.3Å; E352-N356 PolarHBondContact O-ND2 3.33Å; E352-N356 VanDerWaalsContact O-ND2 3.16Å
353D96.7Very high93.7Very high53 Ų5342.7 Ų42.728%0.28321%0.207SC..Hα-helixtrans-63.4-44.2177.5-77.1-15000112L262 Y269 N349 L350 M355 N356 K357L262-D353 HydrophobicContact CD1-CB 4.01Å; L262-D353 HydrophobicContact CD2-CB 3.91Å; Y269-D353 PolarHBondContact OH-OD2 3.3Å; N349-D353 WeakPolarHBondContact O-CB 3.39Å; N349-D353 PolarHBondContact O-N 2.88Å; L350-D353 PolarHBondContact O-N 3.03Å; D353-M355 VanDerWaalsContact C-N 3.33Å; D353-M355 PolarHBondContact O-N 3Å; D353-N356 PolarHBondContact O-N 2.96Å; D353-K357 PolarHBondContact O-N 2.62Å; D353-K357 VanDerWaalsContact O-N 3.11Å
354C97.8Very high93.7Very high0 Ų048.8 Ų48.80%023%0.233CC..Hα-helixtrans-55.6-48.5171.4-75.60000111.2M257 A258 L350 A351 N356 K357 F358M257-C354 HydrophobicContact CE-CB 3.92Å; M257-C354 WeakPolarHBondContact CE-O 3.1Å; M257-C354 HydrophobicContact CG-CB 4.21Å; M257-C354 HydrophobicContact SD-CB 3.94Å; A258-C354 VanDerWaalsContact CA-SG 3.59Å; L350-C354 PolarHBondContact O-N 2.79Å; L350-C354 PolarHBondContact O-SG 3.39Å; A351-C354 PolarHBondContact O-N 3.4Å; C354-N356 PolarHBondContact O-N 2.87Å; C354-K357 PolarHBondContact O-N 3.45Å; C354-F358 VanDerWaalsContact O-CB 3.31Å; C354-F358 WeakPolarHBondContact O-CB 3.16Å; C354-F358 PolarHBondContact O-N 2.8Å
355M96.8Very high93.9Very high26 Ų2648.3 Ų48.313%0.12823%0.231CC..Hα-helixtrans-67.6-33.7-178.8-73-52.9-57.900113.5M257 I297 L301 A351 E352 D353 F358 K359M257-M355 HydrophobicContact CE-SD 4.4Å; I297-M355 HydrophobicContact CG1-CG 4.1Å; I297-M355 HydrophobicContact CG1-SD 3.55Å; I297-M355 VanDerWaalsContact CG1-SD 3.55Å; I297-M355 HydrophobicContact CG2-SD 4.09Å; L301-M355 HydrophobicContact CD1-CE 4.43Å; L301-M355 HydrophobicContact CD1-CG 3.69Å; L301-M355 HydrophobicContact CD1-SD 3.88Å; L301-M355 HydrophobicContact CD2-CG 4.23Å; L301-M355 HydrophobicContact CG-CG 4.44Å; A351-M355 WeakPolarHBondContact O-CB 3.39Å; A351-M355 VanDerWaalsContact O-CG 3.3Å; A351-M355 WeakPolarHBondContact O-CG 3.41Å; A351-M355 PolarHBondContact O-N 2.87Å; E352-M355 PolarHBondContact O-N 2.61Å; D353-M355 VanDerWaalsContact C-N 3.33Å; D353-M355 PolarHBondContact O-N 3Å; M355-F358 HydrophobicContact CE-CD1 3.72Å; M355-F358 HydrophobicContact CE-CE1 4.27Å; M355-F358 PolarHBondContact O-N 3.46Å; M355-F358 HydrophobicContact SD-CD1 4.39Å; M355-K359 HydrophobicContact CE-CG 4.35Å; M355-K359 WeakPolarHBondContact O-CB 3.43Å; M355-K359 VanDerWaalsContact O-CG 3.31Å; M355-K359 WeakPolarHBondContact O-CG 3.46Å; M355-K359 PolarHBondContact O-N 2.79Å
356N95.8Very high94.2Very high89 Ų8948.1 Ų48.148%0.47623%0.23SC..Hα-helixtrans-64-47.8175.6-71.7-28.8000110.4E352 D353 C354 F358 L360E352-N356 WeakPolarHBondContact O-CB 3.3Å; E352-N356 PolarHBondContact O-N 3.3Å; E352-N356 PolarHBondContact O-ND2 3.33Å; E352-N356 VanDerWaalsContact O-ND2 3.16Å; D353-N356 PolarHBondContact O-N 2.96Å; C354-N356 PolarHBondContact O-N 2.87Å; N356-F358 VanDerWaalsContact C-N 3.34Å; N356-F358 PolarHBondContact O-N 3.21Å; N356-L360 VanDerWaalsContact O-CD1 3.31Å; N356-L360 WeakPolarHBondContact O-CD1 3.44Å; N356-L360 WeakPolarHBondContact O-CG 3.19Å; N356-L360 PolarHBondContact O-N 2.62Å
357K94.3Very high94.2Very high114 Ų11452.8 Ų52.850%0.49625%0.249SC..Hα-helixtrans-61-44173.8-72.1-69.8-170169.60111.9L261 L262 D353 C354 L360L261-K357 HydrophobicContact CB-CB 4.28Å; L261-K357 HydrophobicContact CD1-CB 4.24Å; L262-K357 HydrophobicContact CD2-CG 4.17Å; D353-K357 PolarHBondContact O-N 2.62Å; D353-K357 VanDerWaalsContact O-N 3.11Å; C354-K357 PolarHBondContact O-N 3.45Å; K357-L360 PolarHBondContact O-N 3.24Å
358F95.4Very high94.3Very high15 Ų1553.5 Ų53.57%0.06625%0.254CS..Iπ-helixtrans-59.7-53-178.8174.3-101.4000113.1L252 M257 C354 M355 N356 L360 I362 E363 L471L252-F358 HydrophobicContact CD1-CE2 3.87Å; L252-F358 HydrophobicContact CD1-CZ 4.18Å; L252-F358 HydrophobicContact CD2-CD2 3.79Å; L252-F358 HydrophobicContact CD2-CE2 3.69Å; L252-F358 HydrophobicContact CG-CE2 4.46Å; M257-F358 HydrophobicContact CE-CB 3.48Å; M257-F358 VanDerWaalsContact CE-CB 3.48Å; M257-F358 HydrophobicContact CE-CD2 4.1Å; M257-F358 HydrophobicContact CE-CG 3.92Å; C354-F358 VanDerWaalsContact O-CB 3.31Å; C354-F358 WeakPolarHBondContact O-CB 3.16Å; C354-F358 PolarHBondContact O-N 2.8Å; M355-F358 HydrophobicContact CE-CD1 3.72Å; M355-F358 HydrophobicContact CE-CE1 4.27Å; M355-F358 PolarHBondContact O-N 3.46Å; M355-F358 HydrophobicContact SD-CD1 4.39Å; N356-F358 VanDerWaalsContact C-N 3.34Å; N356-F358 PolarHBondContact O-N 3.21Å; F358-L360 VanDerWaalsContact C-N 3.31Å; F358-L360 PolarHBondContact O-N 3.46Å; F358-I362 HydrophobicContact CD2-CB 4.25Å; F358-I362 HydrophobicContact CD2-CG2 4.24Å; F358-I362 PolarHBondContact O-N 3.36Å; F358-E363 HydrophobicContact CD1-CB 4.29Å; F358-E363 HydrophobicContact CE1-CB 3.77Å; F358-E363 HydrophobicContact CE1-CG 3.86Å; F358-E363 HydrophobicContact CE2-CB 4.06Å; F358-E363 HydrophobicContact CZ-CB 3.65Å; F358-E363 HydrophobicContact CZ-CG 3.7Å; F358-E363 PolarHBondContact O-N 2.95Å; F358-L471 HydrophobicContact CZ-CD1 3.81Å
359K94.3Very high94.5Very high135 Ų13553 Ų5359%0.58725%0.251SS*.Iπ-helixtrans-67-30.3-176.7-72.6175.9179.2176.30113.6M355M355-K359 HydrophobicContact CE-CG 4.35Å; M355-K359 WeakPolarHBondContact O-CB 3.43Å; M355-K359 VanDerWaalsContact O-CG 3.31Å; M355-K359 WeakPolarHBondContact O-CG 3.46Å; M355-K359 PolarHBondContact O-N 2.79Å
360L89.2Confident94.6Very high131 Ų13152.7 Ų52.769%0.68625%0.25SC*.Iπ-helixtrans-65.2-54.8-178.3-76.9167.6000110.7N356 K357 F358N356-L360 VanDerWaalsContact O-CD1 3.31Å; N356-L360 WeakPolarHBondContact O-CD1 3.44Å; N356-L360 WeakPolarHBondContact O-CG 3.19Å; N356-L360 PolarHBondContact O-N 2.62Å; K357-L360 PolarHBondContact O-N 3.24Å; F358-L360 VanDerWaalsContact C-N 3.31Å; F358-L360 PolarHBondContact O-N 3.46Å
361N85.4Confident94.5Very high58 Ų5853.4 Ų53.431%0.3125%0.253SS..Iπ-helixtrans-136.5-25.1-169.6-69.2-20.3000114.8N398 H399N361-N398 PolarHBondContact ND2-O 3.31Å; N361-N398 WeakPolarHBondContact OD1-CB 3.38Å; N361-H399 PolarHBondContact O-CE1 2.96Å
362I92.3Very high94.5Very high12 Ų1253.5 Ų53.56%0.06225%0.254CS..Iπ-helixtrans-88.9-26.2-166.7-52.4-59.4000113H250 L261 F358 K364 L365 C366H250-I362 HydrophobicContact CB-CG2 4.37Å; L261-I362 HydrophobicContact CD2-CG1 4.11Å; F358-I362 HydrophobicContact CD2-CB 4.25Å; F358-I362 HydrophobicContact CD2-CG2 4.24Å; F358-I362 PolarHBondContact O-N 3.36Å; I362-K364 PolarHBondContact O-N 3.46Å; I362-L365 HydrophobicContact CD1-CD2 4.23Å; I362-L365 CarbonylContact O-C 3.36Å; I362-L365 WeakPolarHBondContact O-CA 3.27Å; I362-L365 WeakPolarHBondContact O-CB 3.49Å; I362-L365 PolarHBondContact O-N 2.92Å; I362-C366 VanDerWaalsContact CG2-SG 3.58Å; I362-C366 PolarHBondContact O-N 3.5Å
363E92.9Very high94.6Very high95 Ų9550.1 Ų50.144%0.44424%0.24SC..Hα-helixtrans-54.4-48.1-176.9-179.8174.4-167.800113.5F358 L365 K367 L471F358-E363 HydrophobicContact CD1-CB 4.29Å; F358-E363 HydrophobicContact CE1-CB 3.77Å; F358-E363 HydrophobicContact CE1-CG 3.86Å; F358-E363 HydrophobicContact CE2-CB 4.06Å; F358-E363 HydrophobicContact CZ-CB 3.65Å; F358-E363 HydrophobicContact CZ-CG 3.7Å; F358-E363 PolarHBondContact O-N 2.95Å; E363-L365 VanDerWaalsContact C-N 3.34Å; E363-K367 PolarHBondContact O-N 3.39Å; E363-L471 HydrophobicContact CG-CD1 4.15Å
364K90Very high94.5Very high169 Ų16949.3 Ų49.374%0.73524%0.235SC*.Hα-helixtrans-68-36.3177.3-67.6-178.1-178.3176.50112.1I362 K367 T368I362-K364 PolarHBondContact O-N 3.46Å; K364-K367 PolarHBondContact O-N 2.84Å; K364-T368 PolarHBondContact O-N 3.24Å
365L94.4Very high94.3Very high0 Ų050.2 Ų50.20%024%0.244CC..Hα-helixtrans-63.3-49177175.659.5000110.5I362 E363 K367 T368 E369 V393 D403 A407I362-L365 HydrophobicContact CD1-CD2 4.23Å; I362-L365 CarbonylContact O-C 3.36Å; I362-L365 WeakPolarHBondContact O-CA 3.27Å; I362-L365 WeakPolarHBondContact O-CB 3.49Å; I362-L365 PolarHBondContact O-N 2.92Å; E363-L365 VanDerWaalsContact C-N 3.34Å; L365-K367 PolarHBondContact O-N 3.17Å; L365-K367 VanDerWaalsContact O-N 3.17Å; L365-T368 WeakPolarHBondContact O-CB 3.2Å; L365-T368 PolarHBondContact O-N 2.86Å; L365-E369 HydrophobicContact CD1-CG 3.89Å; L365-E369 HydrophobicContact CG-CG 4.01Å; L365-E369 WeakPolarHBondContact CG-OE1 3.46Å; L365-E369 WeakPolarHBondContact O-CG 3.49Å; L365-E369 PolarHBondContact O-N 3.17Å; L365-V393 HydrophobicContact CD1-CB 4.43Å; L365-V393 HydrophobicContact CD1-CG1 3.57Å; L365-V393 HydrophobicContact CD1-CG2 3.95Å; L365-D403 HydrophobicContact CD2-CB 3.79Å; L365-A407 HydrophobicContact CD1-CB 4.26Å
366C96Very high94.2Very high0 Ų051 Ų510%025%0.251CS..Hα-helixtrans-52.3-41.6177.9-75.70000112.3I362 E369 Q370 L471I362-C366 VanDerWaalsContact CG2-SG 3.58Å; I362-C366 PolarHBondContact O-N 3.5Å; C366-E369 PolarHBondContact O-N 3.34Å; C366-Q370 VanDerWaalsContact O-CG 3.29Å; C366-Q370 WeakPolarHBondContact O-CG 3.43Å; C366-Q370 PolarHBondContact O-N 3.12Å; C366-L471 HydrophobicContact CB-CB 4.45Å
367K94.8Very high94.1Very high112 Ų11248.8 Ų48.849%0.48724%0.239SC..Hα-helixtrans-56.9-54.5176.6-175.3-179.5177.21770111E363 K364 L365 E369 Q370 D371 L471E363-K367 PolarHBondContact O-N 3.39Å; K364-K367 PolarHBondContact O-N 2.84Å; L365-K367 PolarHBondContact O-N 3.17Å; L365-K367 VanDerWaalsContact O-N 3.17Å; K367-E369 VanDerWaalsContact C-N 3.31Å; K367-E369 PolarHBondContact O-N 3.1Å; K367-Q370 PolarHBondContact O-N 2.83Å; K367-D371 VanDerWaalsContact O-CG 3.22Å; K367-D371 PolarHBondContact O-N 3.02Å; K367-D371 VanDerWaalsContact O-N 3.11Å; K367-L471 HydrophobicContact CB-CD2 3.74Å; K367-L471 HydrophobicContact CG-CD2 4.36Å
368T95.8Very high94Very high16 Ų1644.6 Ų44.610%0.09823%0.226CC..Hα-helixtrans-58-43176.9-70.80000111.7K364 L365 D371 L372 V389 V393K364-T368 PolarHBondContact O-N 3.24Å; L365-T368 WeakPolarHBondContact O-CB 3.2Å; L365-T368 PolarHBondContact O-N 2.86Å; T368-D371 PolarHBondContact O-N 3.03Å; T368-L372 HydrophobicContact CG2-CD1 3.64Å; T368-L372 HydrophobicContact CG2-CG 4.15Å; T368-L372 WeakPolarHBondContact O-CB 3.2Å; T368-L372 VanDerWaalsContact O-CG 3.23Å; T368-L372 WeakPolarHBondContact O-CG 3.34Å; T368-L372 PolarHBondContact O-N 3.45Å; T368-V389 HydrophobicContact CG2-CG1 4.01Å; T368-V389 WeakPolarHBondContact CG2-O 3.39Å; T368-V389 PolarHBondContact OG1-O 3.42Å; T368-V393 HydrophobicContact CG2-CG2 3.58Å
369E97.5Very high93.8Very high0 Ų049.8 Ų49.80%025%0.25CS..Hα-helixtrans-61.9-44.6179.6-68.6-173.3168.800112.7L249 H250 L365 C366 K367 L372 A373 L410L249-E369 HydrophobicContact CD1-CB 4.14Å; H250-E369 WeakPolarHBondContact CB-OE2 3.23Å; H250-E369 IonicContact CE1-OE1 3.29Å; H250-E369 IonicContact CG-OE1 2.71Å; H250-E369 IonicContact CG-OE2 3.16Å; H250-E369 PolarHBondContact N-OE2 3.25Å; H250-E369 VanDerWaalsContact ND1-CD 3.27Å; H250-E369 IonicContact ND1-OE1 4Å; H250-E369 PolarHBondContact ND1-OE1 2.97Å; H250-E369 IonicContact ND1-OE2 2.68Å; H250-E369 PolarHBondContact ND1-OE2 3.46Å; L365-E369 HydrophobicContact CD1-CG 3.89Å; L365-E369 HydrophobicContact CG-CG 4.01Å; L365-E369 WeakPolarHBondContact CG-OE1 3.46Å; L365-E369 WeakPolarHBondContact O-CG 3.49Å; L365-E369 PolarHBondContact O-N 3.17Å; C366-E369 PolarHBondContact O-N 3.34Å; K367-E369 VanDerWaalsContact C-N 3.31Å; K367-E369 PolarHBondContact O-N 3.1Å; E369-L372 PolarHBondContact O-N 3Å; E369-A373 WeakPolarHBondContact O-CB 3.49Å; E369-A373 PolarHBondContact O-N 3.37Å; E369-L410 HydrophobicContact CB-CD1 3.61Å; E369-L410 HydrophobicContact CG-CD1 3.44Å; E369-L410 VanDerWaalsContact CG-CD1 3.44Å
370Q96.8Very high93.6Very high2 Ų245.7 Ų45.71%0.00925%0.246CC..Hα-helixtrans-62.8-44.3176.7-64.4-55.8-59.700111.2C366 K367 L372 A373 L374C366-Q370 VanDerWaalsContact O-CG 3.29Å; C366-Q370 WeakPolarHBondContact O-CG 3.43Å; C366-Q370 PolarHBondContact O-N 3.12Å; K367-Q370 PolarHBondContact O-N 2.83Å; Q370-L372 PolarHBondContact O-N 3.42Å; Q370-A373 PolarHBondContact O-N 2.82Å; Q370-L374 WeakPolarHBondContact O-CB 3.39Å; Q370-L374 PolarHBondContact O-N 2.92Å
371D96.4Very high93.9Very high15 Ų1545.3 Ų45.38%0.0824%0.241CC..Hα-helixtrans-64-41.4-179.6-64.1-7.9000111.3K367 T368 G375 V383 V389 R473K367-D371 VanDerWaalsContact O-CG 3.22Å; K367-D371 PolarHBondContact O-N 3.02Å; K367-D371 VanDerWaalsContact O-N 3.11Å; T368-D371 PolarHBondContact O-N 3.03Å; D371-G375 VanDerWaalsContact O-CA 3.3Å; D371-G375 WeakPolarHBondContact O-CA 3.25Å; D371-G375 PolarHBondContact O-N 3.45Å; D371-V383 HydrophobicContact CB-CG2 4.29Å; D371-V389 HydrophobicContact CB-CG1 4.15Å; D371-R473 IonicContact OD1-NH2 2.76Å; D371-R473 PolarHBondContact OD1-NH2 3.16Å
372L97.2Very high94.4Very high2 Ų252.5 Ų52.51%0.0126%0.264CS..Hα-helixtrans-68.2-42.9176-70.2174.8000112.3T368 E369 Q370 V389 L390 L410 Y411T368-L372 HydrophobicContact CG2-CD1 3.64Å; T368-L372 HydrophobicContact CG2-CG 4.15Å; T368-L372 WeakPolarHBondContact O-CB 3.2Å; T368-L372 VanDerWaalsContact O-CG 3.23Å; T368-L372 WeakPolarHBondContact O-CG 3.34Å; T368-L372 PolarHBondContact O-N 3.45Å; E369-L372 PolarHBondContact O-N 3Å; Q370-L372 PolarHBondContact O-N 3.42Å; L372-V389 HydrophobicContact CD2-CB 4.38Å; L372-V389 HydrophobicContact CG-CG1 4.48Å; L372-L390 HydrophobicContact CD1-CD1 4.16Å; L372-L410 HydrophobicContact CB-CB 4.23Å; L372-L410 HydrophobicContact CD1-CB 4.4Å; L372-Y411 HydrophobicContact CD2-CD2 4.47Å
373A96.3Very high94.5Very high9 Ų953 Ų537%0.07427%0.267CS..Hα-helixtrans-65.1-44.6-17900000112.2V245 L249 E369 Q370 L410 W474V245-A373 HydrophobicContact CG1-CB 3.7Å; L249-A373 HydrophobicContact CD1-CB 3.71Å; E369-A373 WeakPolarHBondContact O-CB 3.49Å; E369-A373 PolarHBondContact O-N 3.37Å; Q370-A373 PolarHBondContact O-N 2.82Å; A373-L410 HydrophobicContact CB-CD2 4.45Å; A373-W474 HydrophobicContact CB-CD2 4.3Å; A373-W474 HydrophobicContact CB-CE3 3.71Å; A373-W474 HydrophobicContact CB-CZ3 4.13Å; A373-W474 WeakPolarHBondContact O-CZ3 3.17Å
374L94.6Very high94.5Very high35 Ų3558.4 Ų58.418%0.18329%0.289CS..Hα-helixtrans-85.8-27.3-177.8-67173000113.3Q370 T376 R460 R473 W474Q370-L374 WeakPolarHBondContact O-CB 3.39Å; Q370-L374 PolarHBondContact O-N 2.92Å; L374-T376 PolarHBondContact O-N 2.97Å; L374-R460 VanDerWaalsContact CD2-NH1 3.25Å; L374-R473 HydrophobicContact CD1-CB 3.44Å; L374-R473 VanDerWaalsContact CD1-CB 3.44Å; L374-W474 HydrophobicContact CD2-CE3 3.81Å; L374-W474 HydrophobicContact CD2-CZ3 4.29Å; L374-W474 HydrophobicContact CG-CE3 4.35Å
375G94.1Very high94.7Very high19 Ų1954 Ų5420%0.19627%0.273CS..SBendtrans73.212.1-169.300000113.4D371 V383D371-G375 VanDerWaalsContact O-CA 3.3Å; D371-G375 WeakPolarHBondContact O-CA 3.25Å; D371-G375 PolarHBondContact O-N 3.45Å; G375-V383 PolarHBondContact O-N 2.89Å
376T94.6Very high94.7Very high43 Ų4355 Ų5526%0.26428%0.281SS..BIsolated β-bridgetrans-134.8142.6175.852.10000111.1L374 Q381 R473L374-T376 PolarHBondContact O-N 2.97Å; T376-Q381 CarbonylContact C-O 3.5Å; T376-Q381 WeakPolarHBondContact CA-O 3.41Å; T376-R473 PolarHBondContact O-NH2 3.41Å
377D94.2Very high94.7Very high42 Ų4256.8 Ų56.823%0.22529%0.29CS..  trans-74.9175.8172.265.817.7000111.9E379 G380 Q381 R473D377-E379 PolarHBondContact O-N 3.43Å; D377-E379 VanDerWaalsContact O-N 3.13Å; D377-E379 WeakPolarHBondContact OD1-CA 3.49Å; D377-E379 WeakPolarHBondContact OD1-CB 3.41Å; D377-E379 PolarHBondContact OD1-N 3.01Å; D377-E379 VanDerWaalsContact OD1-N 3.1Å; D377-G380 PolarHBondContact O-N 2.87Å; D377-G380 PolarHBondContact OD1-N 3.19Å; D377-G380 VanDerWaalsContact OD1-N 3.17Å; D377-Q381 PolarHBondContact N-O 3.22Å; D377-Q381 WeakPolarHBondContact OD1-CA 3.37Å; D377-Q381 WeakPolarHBondContact OD1-CB 3.47Å; D377-Q381 PolarHBondContact OD1-N 3.16Å; D377-Q381 WeakPolarHBondContact OD2-CB 3.21Å; D377-R473 VanDerWaalsContact C-NH2 3.3Å; D377-R473 PolarHBondContact O-NH1 3.01Å
378A91.6Very high94.7Very high27 Ų2756.9 Ų56.922%0.22330%0.295CS..THydrogen-bonded Turntrans-60.1-19.7-178.100000113.7G380 Q470A378-G380 VanDerWaalsContact C-N 3.33Å; A378-Q470 HydrophobicContact CB-CB 4.22Å; A378-Q470 HydrophobicContact CB-CG 4.15Å
379E91.8Very high94.7Very high124 Ų12457.7 Ų57.758%0.57930%0.3SS*.THydrogen-bonded Turntrans-91.84.6176.5-63.370.7-150.300112.5D377 Q381D377-E379 PolarHBondContact O-N 3.43Å; D377-E379 VanDerWaalsContact O-N 3.13Å; D377-E379 WeakPolarHBondContact OD1-CA 3.49Å; D377-E379 WeakPolarHBondContact OD1-CB 3.41Å; D377-E379 PolarHBondContact OD1-N 3.01Å; D377-E379 VanDerWaalsContact OD1-N 3.1Å; E379-Q381 HydrophobicContact CB-CG 4.31Å; E379-Q381 PolarHBondContact O-N 3.26Å
380G90.9Very high94.7Very high49 Ų4957.7 Ų57.751%0.50530%0.3SS..SBendtrans75.68.6-179.500000113.9D377 A378D377-G380 PolarHBondContact O-N 2.87Å; D377-G380 PolarHBondContact OD1-N 3.19Å; D377-G380 VanDerWaalsContact OD1-N 3.17Å; A378-G380 VanDerWaalsContact C-N 3.33Å
381Q94.7Very high94.6Very high123 Ų12360.9 Ų60.958%0.57532%0.316SS*.  trans-79138.9177.7-54.7-60.3-60.900110.1T376 D377 E379 V383T376-Q381 CarbonylContact C-O 3.5Å; T376-Q381 WeakPolarHBondContact CA-O 3.41Å; D377-Q381 PolarHBondContact N-O 3.22Å; D377-Q381 WeakPolarHBondContact OD1-CA 3.37Å; D377-Q381 WeakPolarHBondContact OD1-CB 3.47Å; D377-Q381 PolarHBondContact OD1-N 3.16Å; D377-Q381 WeakPolarHBondContact OD2-CB 3.21Å; E379-Q381 HydrophobicContact CB-CG 4.31Å; E379-Q381 PolarHBondContact O-N 3.26Å; Q381-V383 PolarHBondContact O-N 2.72Å
382R94.9Very high94.5Very high209 Ų20964 Ų6479%0.78934%0.337SS*.BIsolated β-bridgetrans-63.2128.6178.1-174.9177.8177.2-175.80.2110.8K384R382-K384 PolarHBondContact O-N 3.35Å; R382-K384 VanDerWaalsContact O-N 3.14Å
383V94.9Very high94.3Very high21 Ų2164.1 Ų64.113%0.12734%0.338CS..  trans-65.5112.9170.8177.20000108.5D371 G375 Q381 V389D371-V383 HydrophobicContact CB-CG2 4.29Å; G375-V383 PolarHBondContact O-N 2.89Å; Q381-V383 PolarHBondContact O-N 2.72Å; V383-V389 HydrophobicContact CG1-CG2 3.67Å
384K92.5Very high94.2Very high209 Ų20964.5 Ų64.591%0.90934%0.339SS*.SBendtrans-77.3-39-177.3-68.1-178.5-179.7175.60112.7R382R382-K384 PolarHBondContact O-N 3.35Å; R382-K384 VanDerWaalsContact O-N 3.14Å
385D94.6Very high94.1Very high76 Ų7669.2 Ų69.241%0.40636%0.363SS..  trans-134.696.2-178.8-172.3-22.3000109.3M387 L388D385-M387 PolarHBondContact O-N 2.93Å; D385-M387 WeakPolarHBondContact OD1-CA 3.1Å; D385-M387 VanDerWaalsContact OD1-CB 3.26Å; D385-M387 WeakPolarHBondContact OD1-CB 3.34Å; D385-M387 PolarHBondContact OD1-N 3.15Å; D385-L388 HydrophobicContact CB-CB 4.27Å; D385-L388 HydrophobicContact CB-CD1 3.95Å; D385-L388 HydrophobicContact CB-CG 4.05Å; D385-L388 PolarHBondContact O-N 2.95Å; D385-L388 PolarHBondContact OD1-N 3.4Å; D385-L388 WeakPolarHBondContact OD2-CG 3.44Å
386S95.5Very high94Very high22 Ų2270.5 Ų70.515%0.15437%0.366CS..Hα-helixtrans-63.9-24.6179.7-53.60000112.6V389 L390S386-V389 PolarHBondContact O-N 3.2Å; S386-L390 WeakPolarHBondContact O-CB 3.29Å; S386-L390 PolarHBondContact O-N 3.43Å; S386-L390 VanDerWaalsContact O-N 3.09Å
387M95.5Very high93.8Very high38 Ų3877.7 Ų77.719%0.18739%0.394CS..Hα-helixtrans-69.2-40.5177.4-172.9596700110.9D385 V389 L390 L391 Y411 L426D385-M387 PolarHBondContact O-N 2.93Å; D385-M387 WeakPolarHBondContact OD1-CA 3.1Å; D385-M387 VanDerWaalsContact OD1-CB 3.26Å; D385-M387 WeakPolarHBondContact OD1-CB 3.34Å; D385-M387 PolarHBondContact OD1-N 3.15Å; M387-V389 PolarHBondContact O-N 3.04Å; M387-L390 PolarHBondContact O-N 3.15Å; M387-L390 VanDerWaalsContact O-N 3.11Å; M387-L390 HydrophobicContact SD-CD2 4.12Å; M387-L391 HydrophobicContact CG-CD1 4.34Å; M387-L391 HydrophobicContact CG-CG 4.27Å; M387-L391 WeakPolarHBondContact O-CG 3.42Å; M387-L391 PolarHBondContact O-N 3.35Å; M387-L391 HydrophobicContact SD-CG 4.41Å; M387-Y411 HydrophobicContact CE-CE1 3.92Å; M387-Y411 HydrophobicContact CE-CE2 3.94Å; M387-L426 HydrophobicContact CE-CD1 4.22Å; M387-L426 HydrophobicContact CE-CD2 4.02Å; M387-L426 HydrophobicContact CE-CG 4.44Å; M387-L426 HydrophobicContact SD-CD2 4.04Å
388L95.1Very high93.5Very high113 Ų11380.6 Ų80.659%0.59241%0.409SS*.Hα-helixtrans-62.2-31.2175.3-71.1-179.9000112.8D385 L391 P392D385-L388 HydrophobicContact CB-CB 4.27Å; D385-L388 HydrophobicContact CB-CD1 3.95Å; D385-L388 HydrophobicContact CB-CG 4.05Å; D385-L388 PolarHBondContact O-N 2.95Å; D385-L388 PolarHBondContact OD1-N 3.4Å; D385-L388 WeakPolarHBondContact OD2-CG 3.44Å; L388-L391 HydrophobicContact CD2-CD1 4.41Å; L388-P392 WeakPolarHBondContact O-CD 3.4Å
389V95.5Very high93.5Very high34 Ų3479.7 Ų79.721%0.20640%0.4CS..Hα-helixtrans-74.1-34.4175.1-173.90000111.4T368 D371 L372 V383 S386 M387T368-V389 HydrophobicContact CG2-CG1 4.01Å; T368-V389 WeakPolarHBondContact CG2-O 3.39Å; T368-V389 PolarHBondContact OG1-O 3.42Å; D371-V389 HydrophobicContact CB-CG1 4.15Å; L372-V389 HydrophobicContact CD2-CB 4.38Å; L372-V389 HydrophobicContact CG-CG1 4.48Å; V383-V389 HydrophobicContact CG1-CG2 3.67Å; S386-V389 PolarHBondContact O-N 3.2Å; M387-V389 PolarHBondContact O-N 3.04Å
390L96.2Very high93.5Very high0 Ų076.8 Ų76.80%039%0.389CS..Hα-helixtrans-75.3-41.9-179.6178.763.5000113.3L372 S386 M387 P392 V393 L394 A407 Y411 L426L372-L390 HydrophobicContact CD1-CD1 4.16Å; S386-L390 WeakPolarHBondContact O-CB 3.29Å; S386-L390 PolarHBondContact O-N 3.43Å; S386-L390 VanDerWaalsContact O-N 3.09Å; M387-L390 PolarHBondContact O-N 3.15Å; M387-L390 VanDerWaalsContact O-N 3.11Å; M387-L390 HydrophobicContact SD-CD2 4.12Å; L390-P392 VanDerWaalsContact C-CD 3.48Å; L390-V393 WeakPolarHBondContact O-CB 3.32Å; L390-V393 PolarHBondContact O-N 3.5Å; L390-L394 HydrophobicContact CD1-CD1 4.38Å; L390-L394 HydrophobicContact CD1-CD2 4.03Å; L390-L394 HydrophobicContact CD1-CG 4.09Å; L390-L394 HydrophobicContact CD2-CD1 3.88Å; L390-L394 HydrophobicContact CD2-CG 4.48Å; L390-L394 HydrophobicContact CG-CD1 3.76Å; L390-L394 HydrophobicContact CG-CD2 4.32Å; L390-L394 HydrophobicContact CG-CG 3.88Å; L390-L394 PolarHBondContact O-N 3.07Å; L390-A407 HydrophobicContact CD1-CB 3.7Å; L390-Y411 HydrophobicContact CD2-CD1 4.12Å; L390-Y411 HydrophobicContact CD2-CD2 4.23Å; L390-Y411 HydrophobicContact CD2-CG 3.76Å; L390-L426 HydrophobicContact CD2-CD2 4.27Å
391L95.2Very high93.7Very high68 Ų6877.8 Ų77.836%0.35638%0.382SS..Hα-helixtrans-52.1-43.3-172-78171.1000114.9M387 L388 V393 L394 L395M387-L391 HydrophobicContact CG-CD1 4.34Å; M387-L391 HydrophobicContact CG-CG 4.27Å; M387-L391 WeakPolarHBondContact O-CG 3.42Å; M387-L391 PolarHBondContact O-N 3.35Å; M387-L391 HydrophobicContact SD-CG 4.41Å; L388-L391 HydrophobicContact CD2-CD1 4.41Å; L391-V393 PolarHBondContact O-N 2.91Å; L391-L394 PolarHBondContact O-N 3.43Å; L391-L394 VanDerWaalsContact O-N 3.17Å; L391-L395 WeakPolarHBondContact O-CB 3.3Å; L391-L395 VanDerWaalsContact O-CG 3.29Å; L391-L395 WeakPolarHBondContact O-CG 3.39Å; L391-L395 PolarHBondContact O-N 3.24Å
392P94Very high93.7Very high81 Ų8173 Ų7353%0.52636%0.362SS..Hα-helixtrans-57.9-34.3177.3-26.635.6000113.8L388 L390 N396L388-P392 WeakPolarHBondContact O-CD 3.4Å; L390-P392 VanDerWaalsContact C-CD 3.48Å; P392-N396 WeakPolarHBondContact O-CB 3.14Å; P392-N396 PolarHBondContact O-N 2.71Å
393V94.3Very high93.7Very high4 Ų463.7 Ų63.72%0.02433%0.328CS..Hα-helixtrans-69.8-46.5176.5174.20000110.3L365 T368 L390 L391 L395 N396 H399 A407L365-V393 HydrophobicContact CD1-CB 4.43Å; L365-V393 HydrophobicContact CD1-CG1 3.57Å; L365-V393 HydrophobicContact CD1-CG2 3.95Å; T368-V393 HydrophobicContact CG2-CG2 3.58Å; L390-V393 WeakPolarHBondContact O-CB 3.32Å; L390-V393 PolarHBondContact O-N 3.5Å; L391-V393 PolarHBondContact O-N 2.91Å; V393-L395 VanDerWaalsContact C-N 3.31Å; V393-L395 PolarHBondContact O-N 2.61Å; V393-N396 PolarHBondContact O-N 3.07Å; V393-H399 PolarHBondContact O-CD2 3.42Å; V393-A407 HydrophobicContact CG1-CB 3.77Å
394L94.3Very high93.8Very high18 Ų1863.9 Ų63.99%0.09433%0.327CS..Hα-helixtrans-64.4-36.6-177.9-58.3-174.2000112.7L390 L391 K404 V408 L426 V430L390-L394 HydrophobicContact CD1-CD1 4.38Å; L390-L394 HydrophobicContact CD1-CD2 4.03Å; L390-L394 HydrophobicContact CD1-CG 4.09Å; L390-L394 HydrophobicContact CD2-CD1 3.88Å; L390-L394 HydrophobicContact CD2-CG 4.48Å; L390-L394 HydrophobicContact CG-CD1 3.76Å; L390-L394 HydrophobicContact CG-CD2 4.32Å; L390-L394 HydrophobicContact CG-CG 3.88Å; L390-L394 PolarHBondContact O-N 3.07Å; L391-L394 PolarHBondContact O-N 3.43Å; L391-L394 VanDerWaalsContact O-N 3.17Å; L394-K404 HydrophobicContact CD2-CB 4.24Å; L394-K404 HydrophobicContact CD2-CG 4.48Å; L394-K404 PolarHBondContact O-NZ 3.29Å; L394-V408 HydrophobicContact CD1-CG2 4.5Å; L394-V408 HydrophobicContact CD2-CG2 3.8Å; L394-L426 HydrophobicContact CD1-CD2 3.83Å; L394-V430 HydrophobicContact CB-CG2 4.1Å; L394-V430 HydrophobicContact CD1-CG2 3.81Å; L394-V430 HydrophobicContact CD2-CG2 3.86Å; L394-V430 HydrophobicContact CG-CG2 4.12Å
395L92.6Very high94Very high133 Ų13354 Ų5470%0.69628%0.284SS*.Hα-helixtrans-79.7-18.5-179.2-65.9174000113.6L391 V393 K397L391-L395 WeakPolarHBondContact O-CB 3.3Å; L391-L395 VanDerWaalsContact O-CG 3.29Å; L391-L395 WeakPolarHBondContact O-CG 3.39Å; L391-L395 PolarHBondContact O-N 3.24Å; V393-L395 VanDerWaalsContact C-N 3.31Å; V393-L395 PolarHBondContact O-N 2.61Å; L395-K397 PolarHBondContact O-N 2.88Å
396N91.6Very high94.2Very high47 Ų4750.7 Ų50.725%0.25127%0.266SS..  trans-74.8119.6-179.3179.16.4000110.6P392 V393 N398 H399 K404P392-N396 WeakPolarHBondContact O-CB 3.14Å; P392-N396 PolarHBondContact O-N 2.71Å; V393-N396 PolarHBondContact O-N 3.07Å; N396-N398 PolarHBondContact O-N 3.43Å; N396-N398 WeakPolarHBondContact OD1-CB 3.32Å; N396-N398 PolarHBondContact OD1-N 3.32Å; N396-H399 PolarHBondContact ND2-CD2 2.83Å; N396-H399 PolarHBondContact ND2-NE2 3.01Å; N396-H399 PolarHBondContact O-N 3.25Å; N396-K404 WeakPolarHBondContact O-CE 3.43Å
397K89.5Confident94.3Very high193 Ų19349.6 Ų49.684%0.83926%0.259SS*.THydrogen-bonded Turntrans-71.7-14-178.5-65-178.6179.9179.20113.6L395L395-K397 PolarHBondContact O-N 2.88Å
398N89.3Confident94.4Very high103 Ų10347.8 Ų47.855%0.55125%0.25SC*.THydrogen-bonded Turntrans-83.8-15.1-179.6-64.8-7.7000113.3N361 N396N361-N398 PolarHBondContact ND2-O 3.31Å; N361-N398 WeakPolarHBondContact OD1-CB 3.38Å; N396-N398 PolarHBondContact O-N 3.43Å; N396-N398 WeakPolarHBondContact OD1-CB 3.32Å; N396-N398 PolarHBondContact OD1-N 3.32Å
399H91.2Very high94.5Very high9 Ų942.4 Ų42.44%0.04222%0.222CC..SBendtrans-83.8136.1173.5-62.4-55.7000110.4N361 V393 N396 D403 K404N361-H399 PolarHBondContact O-CE1 2.96Å; V393-H399 PolarHBondContact O-CD2 3.42Å; N396-H399 PolarHBondContact ND2-CD2 2.83Å; N396-H399 PolarHBondContact ND2-NE2 3.01Å; N396-H399 PolarHBondContact O-N 3.25Å; H399-D403 HydrophobicContact CB-CB 4.16Å; H399-K404 HydrophobicContact CB-CG 4.16Å; H399-K404 WeakPolarHBondContact O-CE 3.48Å
400D92.1Very high94.7Very high63 Ų6340.8 Ų40.834%0.33721%0.212SC..  trans-74171.8172.97613.8000111.1C402 D403 K404 R571D400-C402 PolarHBondContact O-N 2.89Å; D400-C402 WeakPolarHBondContact OD1-CA 3.05Å; D400-C402 WeakPolarHBondContact OD1-CB 3.46Å; D400-C402 PolarHBondContact OD1-N 3.3Å; D400-D403 PolarHBondContact O-N 3.13Å; D400-D403 PolarHBondContact OD1-N 2.97Å; D400-K404 WeakPolarHBondContact O-CG 3.47Å; D400-K404 PolarHBondContact O-N 3.29Å; D400-R571 IonicContact OD2-NH2 2.65Å; D400-R571 PolarHBondContact OD2-NH2 2.7Å
401N93.8Very high94.7Very high69 Ų6942.1 Ų42.137%0.36922%0.217SC..Hα-helixtrans-64.9-30.9179.9-75.60.8000112.2K404 I405 I432N401-K404 PolarHBondContact O-N 3.42Å; N401-I405 WeakPolarHBondContact O-CB 3.41Å; N401-I405 WeakPolarHBondContact O-CD1 3.47Å; N401-I405 WeakPolarHBondContact O-CG1 3.48Å; N401-I405 PolarHBondContact O-N 3.48Å; N401-I432 HydrophobicContact CB-CG2 4.04Å
402C94.8Very high94.8Very high22 Ų2238.9 Ų38.915%0.14920%0.2CC..Hα-helixtrans-66.2-48179.7-171.40000110.7D400 K404 I405 R406D400-C402 PolarHBondContact O-N 2.89Å; D400-C402 WeakPolarHBondContact OD1-CA 3.05Å; D400-C402 WeakPolarHBondContact OD1-CB 3.46Å; D400-C402 PolarHBondContact OD1-N 3.3Å; C402-K404 VanDerWaalsContact C-N 3.3Å; C402-K404 PolarHBondContact O-N 2.92Å; C402-I405 PolarHBondContact O-N 3.29Å; C402-R406 VanDerWaalsContact O-CG 3.26Å; C402-R406 WeakPolarHBondContact O-CG 3.42Å; C402-R406 PolarHBondContact O-N 2.95Å
403D95.5Very high94.9Very high15 Ų1535.7 Ų35.78%0.0818%0.178CC..Hα-helixtrans-58.9-41.2175-73.4-19.1000111.7H250 L365 H399 D400 R406 A407H250-D403 IonicContact CE1-OD1 2.91Å; H250-D403 IonicContact NE2-OD1 3.56Å; L365-D403 HydrophobicContact CD2-CB 3.79Å; H399-D403 HydrophobicContact CB-CB 4.16Å; D400-D403 PolarHBondContact O-N 3.13Å; D400-D403 PolarHBondContact OD1-N 2.97Å; D403-R406 PolarHBondContact O-N 3.47Å; D403-A407 PolarHBondContact O-N 3Å
404K96Very high94.9Very high25 Ų2536 Ų3611%0.10918%0.182CC..Hα-helixtrans-66-42.4176-68.4177.5-174.3-178.60112L394 N396 H399 D400 N401 C402 A407 V408 V430L394-K404 HydrophobicContact CD2-CB 4.24Å; L394-K404 HydrophobicContact CD2-CG 4.48Å; L394-K404 PolarHBondContact O-NZ 3.29Å; N396-K404 WeakPolarHBondContact O-CE 3.43Å; H399-K404 HydrophobicContact CB-CG 4.16Å; H399-K404 WeakPolarHBondContact O-CE 3.48Å; D400-K404 WeakPolarHBondContact O-CG 3.47Å; D400-K404 PolarHBondContact O-N 3.29Å; N401-K404 PolarHBondContact O-N 3.42Å; C402-K404 VanDerWaalsContact C-N 3.3Å; C402-K404 PolarHBondContact O-N 2.92Å; K404-A407 PolarHBondContact O-N 3.41Å; K404-V408 WeakPolarHBondContact O-CG2 3.37Å; K404-V408 PolarHBondContact O-N 3.05Å; K404-V430 HydrophobicContact CB-CG1 3.94Å; K404-V430 HydrophobicContact CD-CG1 3.83Å; K404-V430 HydrophobicContact CG-CG1 4.48Å
405I97.8Very high94.9Very high1 Ų138 Ų381%0.00520%0.195CC..Hα-helixtrans-61.4-45.1175.2-72.4163.1000110.3N401 C402 A407 V408 L409 I432 D435 M438 I439 L574N401-I405 WeakPolarHBondContact O-CB 3.41Å; N401-I405 WeakPolarHBondContact O-CD1 3.47Å; N401-I405 WeakPolarHBondContact O-CG1 3.48Å; N401-I405 PolarHBondContact O-N 3.48Å; C402-I405 PolarHBondContact O-N 3.29Å; I405-A407 VanDerWaalsContact C-N 3.34Å; I405-A407 PolarHBondContact O-N 2.94Å; I405-V408 PolarHBondContact O-N 3.01Å; I405-L409 HydrophobicContact CG2-CD1 3.91Å; I405-L409 HydrophobicContact CG2-CG 4.36Å; I405-L409 WeakPolarHBondContact O-CB 3.39Å; I405-L409 VanDerWaalsContact O-CG 3.3Å; I405-L409 WeakPolarHBondContact O-CG 3.03Å; I405-L409 PolarHBondContact O-N 2.94Å; I405-I432 HydrophobicContact CD1-CG2 4.32Å; I405-I432 HydrophobicContact CG1-CB 4.5Å; I405-I432 HydrophobicContact CG1-CD1 3.7Å; I405-I432 HydrophobicContact CG1-CG2 4.3Å; I405-D435 HydrophobicContact CD1-CB 3.65Å; I405-M438 HydrophobicContact CD1-SD 3.85Å; I405-M438 HydrophobicContact CG2-CB 4.18Å; I405-I439 HydrophobicContact CG2-CG1 4.09Å; I405-L574 HydrophobicContact CG2-CD1 4.28Å; I405-L574 HydrophobicContact CG2-CD2 4.35Å
406R97.7Very high94.9Very high6 Ų632.8 Ų32.82%0.02317%0.168CC..Hα-helixtrans-57.2-46175.2-68.3165.968158.511.8111.4V248 H250 D260 C402 D403 L409 L410 L574V248-R406 HydrophobicContact CB-CB 4.44Å; V248-R406 HydrophobicContact CB-CG 4.26Å; V248-R406 VanDerWaalsContact O-CZ 3.29Å; V248-R406 PolarHBondContact O-NE 3.06Å; V248-R406 PolarHBondContact O-NH2 3.47Å; H250-R406 PolarHBondContact CD2-NH2 3.17Å; H250-R406 PolarHBondContact CE1-NH1 3.16Å; H250-R406 VanDerWaalsContact CE1-NH1 3.29Å; H250-R406 PolarHBondContact ND1-NH2 2.81Å; H250-R406 PolarHBondContact NE2-NH1 2.96Å; D260-R406 IonicContact OD1-CZ 2.62Å; D260-R406 IonicContact OD1-NH1 2.61Å; D260-R406 PolarHBondContact OD1-NH1 3.41Å; D260-R406 IonicContact OD1-NH2 3.72Å; D260-R406 IonicContact OD2-CZ 2.79Å; D260-R406 IonicContact OD2-NH1 2.62Å; D260-R406 PolarHBondContact OD2-NH1 2.91Å; D260-R406 VanDerWaalsContact OD2-NH1 3.16Å; D260-R406 IonicContact OD2-NH2 3Å; D260-R406 PolarHBondContact OD2-NH2 3.37Å; C402-R406 VanDerWaalsContact O-CG 3.26Å; C402-R406 WeakPolarHBondContact O-CG 3.42Å; C402-R406 PolarHBondContact O-N 2.95Å; D403-R406 PolarHBondContact O-N 3.47Å; R406-L409 WeakPolarHBondContact O-CB 3.42Å; R406-L409 PolarHBondContact O-N 3.35Å; R406-L410 WeakPolarHBondContact O-CG 3.4Å; R406-L410 PolarHBondContact O-N 3.46Å; R406-L574 HydrophobicContact CG-CD1 4.03Å
407A97.4Very high95.1Very high0 Ų031.2 Ų31.20%016%0.162CC..Hα-helixtrans-64.4-41.2177.400000112.9L365 L390 V393 D403 K404 I405 L410 Y411L365-A407 HydrophobicContact CD1-CB 4.26Å; L390-A407 HydrophobicContact CD1-CB 3.7Å; V393-A407 HydrophobicContact CG1-CB 3.77Å; D403-A407 PolarHBondContact O-N 3Å; K404-A407 PolarHBondContact O-N 3.41Å; I405-A407 VanDerWaalsContact C-N 3.34Å; I405-A407 PolarHBondContact O-N 2.94Å; A407-L410 PolarHBondContact O-N 3.28Å; A407-Y411 PolarHBondContact O-N 2.84Å
408V97.9Very high95.4Very high0 Ų022.8 Ų22.80%013%0.127CC..Hα-helixtrans-62-44173.9171.10000110.9L394 K404 I405 Y411 I412 L426 I439L394-V408 HydrophobicContact CD1-CG2 4.5Å; L394-V408 HydrophobicContact CD2-CG2 3.8Å; K404-V408 WeakPolarHBondContact O-CG2 3.37Å; K404-V408 PolarHBondContact O-N 3.05Å; I405-V408 PolarHBondContact O-N 3.01Å; V408-Y411 WeakPolarHBondContact O-CB 3.43Å; V408-Y411 PolarHBondContact O-N 2.74Å; V408-I412 HydrophobicContact CG1-CD1 3.86Å; V408-I412 HydrophobicContact CG1-CG1 4.45Å; V408-I412 WeakPolarHBondContact O-CG1 3.15Å; V408-I412 PolarHBondContact O-N 3.49Å; V408-L426 HydrophobicContact CG1-CD1 4.36Å; V408-I439 HydrophobicContact CB-CD1 4.49Å; V408-I439 HydrophobicContact CG1-CD1 3.92Å
409L98.5Very high95.7Very high0 Ų021.6 Ų21.60%012%0.124CC..Hα-helixtrans-60.6-47176.3-75.3172.2000111.6V248 I405 R406 Y411 I412 F413 I439 W442 L574V248-L409 HydrophobicContact CG1-CD1 4.05Å; V248-L409 HydrophobicContact CG2-CB 4.36Å; I405-L409 HydrophobicContact CG2-CD1 3.91Å; I405-L409 HydrophobicContact CG2-CG 4.36Å; I405-L409 WeakPolarHBondContact O-CB 3.39Å; I405-L409 VanDerWaalsContact O-CG 3.3Å; I405-L409 WeakPolarHBondContact O-CG 3.03Å; I405-L409 PolarHBondContact O-N 2.94Å; R406-L409 WeakPolarHBondContact O-CB 3.42Å; R406-L409 PolarHBondContact O-N 3.35Å; L409-Y411 VanDerWaalsContact C-N 3.29Å; L409-Y411 PolarHBondContact O-N 3.22Å; L409-I412 PolarHBondContact O-N 2.77Å; L409-I412 VanDerWaalsContact O-N 3.12Å; L409-F413 HydrophobicContact CB-CD2 4.39Å; L409-F413 HydrophobicContact CB-CE2 3.77Å; L409-F413 HydrophobicContact CB-CZ 3.93Å; L409-F413 HydrophobicContact CD2-CE1 4.14Å; L409-F413 HydrophobicContact CD2-CE2 4.43Å; L409-F413 HydrophobicContact CD2-CZ 3.72Å; L409-F413 HydrophobicContact CG-CZ 4.32Å; L409-F413 WeakPolarHBondContact O-CB 3.13Å; L409-F413 VanDerWaalsContact O-CD2 3.23Å; L409-F413 WeakPolarHBondContact O-CD2 3.34Å; L409-F413 WeakPolarHBondContact O-CG 3.29Å; L409-F413 PolarHBondContact O-N 3.2Å; L409-I439 HydrophobicContact CD2-CB 4.3Å; L409-I439 HydrophobicContact CD2-CG1 4.22Å; L409-I439 HydrophobicContact CD2-CG2 4.05Å; L409-I439 HydrophobicContact CG-CG1 4.38Å; L409-W442 VanDerWaalsContact CD2-CD1 3.49Å; L409-W442 HydrophobicContact CD2-CG 4.3Å; L409-L574 HydrophobicContact CD1-CD2 3.53Å
410L98.2Very high96Very high0 Ų024.5 Ų24.50%014%0.137CC..Hα-helixtrans-60.8-38176.1-71.8169.4000112.5V245 V248 L249 E369 L372 A373 R406 A407 G414V245-L410 HydrophobicContact CB-CD2 4.41Å; V245-L410 HydrophobicContact CG1-CD2 3.74Å; V248-L410 HydrophobicContact CG2-CD2 3.8Å; V248-L410 HydrophobicContact CG2-CG 3.89Å; L249-L410 HydrophobicContact CB-CD2 4.35Å; L249-L410 HydrophobicContact CD1-CD1 4.35Å; L249-L410 HydrophobicContact CD1-CD2 4.16Å; E369-L410 HydrophobicContact CB-CD1 3.61Å; E369-L410 HydrophobicContact CG-CD1 3.44Å; E369-L410 VanDerWaalsContact CG-CD1 3.44Å; L372-L410 HydrophobicContact CB-CB 4.23Å; L372-L410 HydrophobicContact CD1-CB 4.4Å; A373-L410 HydrophobicContact CB-CD2 4.45Å; R406-L410 WeakPolarHBondContact O-CG 3.4Å; R406-L410 PolarHBondContact O-N 3.46Å; A407-L410 PolarHBondContact O-N 3.28Å; L410-G414 WeakPolarHBondContact O-CA 3.38Å; L410-G414 PolarHBondContact O-N 2.9Å
411Y97.5Very high96.2Very high27 Ų2727.6 Ų27.611%0.10615%0.15CC..Hα-helixtrans-60.1-51.9170.6162.3-96.9000111.3L372 M387 L390 A407 V408 L409 F413 G414 V415 N422 L426L372-Y411 HydrophobicContact CD2-CD2 4.47Å; M387-Y411 HydrophobicContact CE-CE1 3.92Å; M387-Y411 HydrophobicContact CE-CE2 3.94Å; L390-Y411 HydrophobicContact CD2-CD1 4.12Å; L390-Y411 HydrophobicContact CD2-CD2 4.23Å; L390-Y411 HydrophobicContact CD2-CG 3.76Å; A407-Y411 PolarHBondContact O-N 2.84Å; V408-Y411 WeakPolarHBondContact O-CB 3.43Å; V408-Y411 PolarHBondContact O-N 2.74Å; L409-Y411 VanDerWaalsContact C-N 3.29Å; L409-Y411 PolarHBondContact O-N 3.22Å; Y411-F413 PolarHBondContact O-N 3.17Å; Y411-G414 CarbonylContact O-C 3.29Å; Y411-G414 WeakPolarHBondContact O-CA 3.38Å; Y411-G414 PolarHBondContact O-N 3.04Å; Y411-G414 VanDerWaalsContact O-N 3.15Å; Y411-V415 HydrophobicContact CE1-CG2 4.32Å; Y411-V415 HydrophobicContact CE2-CG1 4.2Å; Y411-V415 HydrophobicContact CE2-CG2 4.46Å; Y411-V415 VanDerWaalsContact O-CG2 3.31Å; Y411-V415 WeakPolarHBondContact O-CG2 3.39Å; Y411-V415 PolarHBondContact O-N 3.1Å; Y411-N422 PolarHBondContact OH-ND2 3.34Å; Y411-L426 HydrophobicContact CD1-CD1 4.25Å; Y411-L426 HydrophobicContact CE1-CD1 4.06Å
412I97Very high96.3Very high0 Ų025.8 Ų25.80%014%0.14CC..Hα-helixtrans-61.4-46-178.4-65.9169.3000111V408 L409 G414 V415 N416 G417 T418 L423 I439 I449V408-I412 HydrophobicContact CG1-CD1 3.86Å; V408-I412 HydrophobicContact CG1-CG1 4.45Å; V408-I412 WeakPolarHBondContact O-CG1 3.15Å; V408-I412 PolarHBondContact O-N 3.49Å; L409-I412 PolarHBondContact O-N 2.77Å; L409-I412 VanDerWaalsContact O-N 3.12Å; I412-G414 VanDerWaalsContact C-N 3.31Å; I412-G414 PolarHBondContact O-N 2.95Å; I412-V415 CarbonylContact O-C 3.53Å; I412-V415 PolarHBondContact O-N 3.12Å; I412-N416 WeakPolarHBondContact O-CA 3.45Å; I412-N416 PolarHBondContact O-N 3.27Å; I412-G417 PolarHBondContact O-N 3.2Å; I412-T418 HydrophobicContact CD1-CG2 4.13Å; I412-T418 HydrophobicContact CG1-CG2 4Å; I412-T418 HydrophobicContact CG2-CG2 4.46Å; I412-L423 HydrophobicContact CD1-CD1 3.98Å; I412-I439 HydrophobicContact CD1-CG2 3.67Å; I412-I449 HydrophobicContact CG2-CD1 3.84Å
413F96.5Very high96.4Very high15 Ų1524.8 Ų24.87%0.06613%0.133CC..Hα-helixtrans-63.4-40.8175.7-55.6-25.4000111P244 V245 V248 L409 Y411 V415 N416 W442 V447 I449P244-F413 HydrophobicContact CB-CD1 4.23Å; P244-F413 HydrophobicContact CB-CD2 3.94Å; P244-F413 HydrophobicContact CB-CE1 3.98Å; P244-F413 HydrophobicContact CB-CE2 3.66Å; P244-F413 HydrophobicContact CB-CG 4.22Å; P244-F413 HydrophobicContact CB-CZ 3.68Å; P244-F413 HydrophobicContact CG-CD1 4.18Å; P244-F413 HydrophobicContact CG-CD2 4.19Å; P244-F413 HydrophobicContact CG-CE1 4.39Å; P244-F413 HydrophobicContact CG-CE2 4.39Å; P244-F413 HydrophobicContact CG-CG 4.09Å; P244-F413 HydrophobicContact CG-CZ 4.49Å; P244-F413 VanDerWaalsContact O-CE2 3.22Å; P244-F413 WeakPolarHBondContact O-CE2 3.01Å; V245-F413 HydrophobicContact CG2-CB 3.87Å; V245-F413 HydrophobicContact CG2-CD2 4.15Å; V245-F413 HydrophobicContact CG2-CG 4.43Å; V248-F413 HydrophobicContact CG2-CD2 4.37Å; V248-F413 HydrophobicContact CG2-CE2 3.9Å; L409-F413 HydrophobicContact CB-CD2 4.39Å; L409-F413 HydrophobicContact CB-CE2 3.77Å; L409-F413 HydrophobicContact CB-CZ 3.93Å; L409-F413 HydrophobicContact CD2-CE1 4.14Å; L409-F413 HydrophobicContact CD2-CE2 4.43Å; L409-F413 HydrophobicContact CD2-CZ 3.72Å; L409-F413 HydrophobicContact CG-CZ 4.32Å; L409-F413 WeakPolarHBondContact O-CB 3.13Å; L409-F413 VanDerWaalsContact O-CD2 3.23Å; L409-F413 WeakPolarHBondContact O-CD2 3.34Å; L409-F413 WeakPolarHBondContact O-CG 3.29Å; L409-F413 PolarHBondContact O-N 3.2Å; Y411-F413 PolarHBondContact O-N 3.17Å; F413-V415 VanDerWaalsContact C-N 3.26Å; F413-V415 PolarHBondContact O-N 3.01Å; F413-N416 PolarHBondContact O-N 3.13Å; F413-N416 VanDerWaalsContact O-N 3.13Å; F413-W442 HydrophobicContact CE1-CD2 4.25Å; F413-W442 HydrophobicContact CE1-CE3 4.47Å; F413-W442 HydrophobicContact CE1-CG 4.35Å; F413-W442 AromaticContact CZ-CD2 3.71Å; F413-W442 HydrophobicContact CZ-CD2 3.71Å; F413-W442 AromaticContact CZ-CE2 3.77Å; F413-W442 HydrophobicContact CZ-CE3 4.02Å; F413-W442 HydrophobicContact CZ-CG 4.13Å; F413-W442 HydrophobicContact CZ-CH2 4.44Å; F413-W442 HydrophobicContact CZ-CZ2 4.14Å; F413-W442 HydrophobicContact CZ-CZ3 4.37Å; F413-V447 HydrophobicContact CD1-CG1 3.75Å; F413-V447 HydrophobicContact CE1-CG1 3.54Å; F413-V447 HydrophobicContact CZ-CG1 4.49Å; F413-I449 HydrophobicContact CE1-CD1 3.94Å
414G93.9Very high96.5Very high11 Ų1127.7 Ų27.711%0.11315%0.149CC..Hα-helixtrans-65.6-20.1176.500000114.3L410 Y411 I412 K457L410-G414 WeakPolarHBondContact O-CA 3.38Å; L410-G414 PolarHBondContact O-N 2.9Å; Y411-G414 CarbonylContact O-C 3.29Å; Y411-G414 WeakPolarHBondContact O-CA 3.38Å; Y411-G414 PolarHBondContact O-N 3.04Å; Y411-G414 VanDerWaalsContact O-N 3.15Å; I412-G414 VanDerWaalsContact C-N 3.31Å; I412-G414 PolarHBondContact O-N 2.95Å; G414-K457 WeakPolarHBondContact O-CE 3.29Å; G414-K457 PolarHBondContact O-NZ 3.47Å
415V92.9Very high96.6Very high60 Ų6034.1 Ų34.136%0.36417%0.172SC..Hα-helixtrans-109.30.7170.2-63.60000113.4Y411 I412 F413 G417Y411-V415 HydrophobicContact CE1-CG2 4.32Å; Y411-V415 HydrophobicContact CE2-CG1 4.2Å; Y411-V415 HydrophobicContact CE2-CG2 4.46Å; Y411-V415 VanDerWaalsContact O-CG2 3.31Å; Y411-V415 WeakPolarHBondContact O-CG2 3.39Å; Y411-V415 PolarHBondContact O-N 3.1Å; I412-V415 CarbonylContact O-C 3.53Å; I412-V415 PolarHBondContact O-N 3.12Å; F413-V415 VanDerWaalsContact C-N 3.26Å; F413-V415 PolarHBondContact O-N 3.01Å; V415-G417 WeakPolarHBondContact CG2-O 3.43Å
416N94Very high96.5Very high23 Ų2334.6 Ų34.612%0.12318%0.175CC..THydrogen-bonded Turntrans59.440.7-177.1-153.837.8000113.8I412 F413 P448 Q455 K457I412-N416 WeakPolarHBondContact O-CA 3.45Å; I412-N416 PolarHBondContact O-N 3.27Å; F413-N416 PolarHBondContact O-N 3.13Å; F413-N416 VanDerWaalsContact O-N 3.13Å; N416-P448 WeakPolarHBondContact OD1-CG 3.08Å; N416-Q455 PolarHBondContact ND2-O 2.93Å; N416-K457 HydrophobicContact CB-CG 3.84Å
417G95.4Very high96.4Very high13 Ų1334.7 Ų34.713%0.13418%0.176CC..  trans118.2163.9179.600000114.2I412 V415 I449I412-G417 PolarHBondContact O-N 3.2Å; V415-G417 WeakPolarHBondContact CG2-O 3.43Å; G417-I449 CarbonylContact C-O 3.58Å; G417-I449 WeakPolarHBondContact CA-O 3.28Å
418T95.5Very high96.4Very high16 Ų1640.5 Ų40.510%0.09820%0.202CC..  trans-137169.9179.2179.50000110.1I412 N422 L423 I449 V450I412-T418 HydrophobicContact CD1-CG2 4.13Å; I412-T418 HydrophobicContact CG1-CG2 4Å; I412-T418 HydrophobicContact CG2-CG2 4.46Å; T418-N422 WeakPolarHBondContact OG1-CB 3.11Å; T418-N422 PolarHBondContact OG1-ND2 3.25Å; T418-L423 HydrophobicContact CG2-CB 3.91Å; T418-I449 WeakPolarHBondContact CG2-O 3.46Å; T418-I449 PolarHBondContact N-O 2.91Å; T418-V450 WeakPolarHBondContact O-CA 3.46Å
419T96Very high96.1Very high78 Ų7846 Ų4648%0.47923%0.232SC..  trans-80.4159.216880.80000111E421 N422 L423T419-E421 VanDerWaalsContact C-N 3.32Å; T419-E421 VanDerWaalsContact CB-OE2 3.22Å; T419-E421 WeakPolarHBondContact CB-OE2 3.34Å; T419-E421 PolarHBondContact O-N 2.99Å; T419-E421 PolarHBondContact OG1-OE2 3.21Å; T419-N422 PolarHBondContact O-N 2.73Å; T419-N422 PolarHBondContact OG1-N 3.28Å; T419-L423 WeakPolarHBondContact O-CB 3.34Å; T419-L423 PolarHBondContact O-N 2.65Å
420E96.8Very high95.9Very high71 Ų7146.6 Ų46.633%0.33224%0.235SC..Hα-helixtrans-58.9-44.6177.4-168.262.9-154.200110.9N422 L423 D424 R440 V450E420-N422 VanDerWaalsContact C-N 3.34Å; E420-N422 PolarHBondContact O-N 3.46Å; E420-L423 PolarHBondContact O-N 3.24Å; E420-D424 PolarHBondContact O-N 2.63Å; E420-R440 IonicContact OE1-CZ 3.11Å; E420-R440 IonicContact OE1-NH1 3.94Å; E420-R440 PolarHBondContact OE1-NH1 3.14Å; E420-R440 IonicContact OE1-NH2 3.83Å; E420-R440 PolarHBondContact OE1-NH2 2.73Å; E420-R440 IonicContact OE2-NH1 2.85Å; E420-R440 PolarHBondContact OE2-NH1 2.85Å; E420-V450 HydrophobicContact CB-CG1 4.27Å; E420-V450 WeakPolarHBondContact OE2-CG2 3.36Å
421E96.8Very high95.7Very high127 Ų12754.3 Ų54.359%0.59327%0.269SS*.Hα-helixtrans-64.9-39.1-179-53.576.2-167.200111.7T419 R425T419-E421 VanDerWaalsContact C-N 3.32Å; T419-E421 VanDerWaalsContact CB-OE2 3.22Å; T419-E421 WeakPolarHBondContact CB-OE2 3.34Å; T419-E421 PolarHBondContact O-N 2.99Å; T419-E421 PolarHBondContact OG1-OE2 3.21Å; E421-R425 WeakPolarHBondContact O-CB 3.39Å; E421-R425 WeakPolarHBondContact O-CD 3.42Å; E421-R425 WeakPolarHBondContact O-CG 3.45Å; E421-R425 PolarHBondContact O-N 2.93Å; E421-R425 VanDerWaalsContact O-N 3.09Å
422N96.1Very high95.6Very high32 Ų3253.1 Ų53.117%0.17126%0.264CS..Hα-helixtrans-71.3-37.4177.3-175.861.5000111.4Y411 T418 T419 E420 R425 L426Y411-N422 PolarHBondContact OH-ND2 3.34Å; T418-N422 WeakPolarHBondContact OG1-CB 3.11Å; T418-N422 PolarHBondContact OG1-ND2 3.25Å; T419-N422 PolarHBondContact O-N 2.73Å; T419-N422 PolarHBondContact OG1-N 3.28Å; E420-N422 VanDerWaalsContact C-N 3.34Å; E420-N422 PolarHBondContact O-N 3.46Å; N422-R425 PolarHBondContact O-N 2.98Å; N422-L426 WeakPolarHBondContact O-CG 3.29Å; N422-L426 PolarHBondContact O-N 2.87Å
423L97.5Very high95.5Very high0 Ų056.9 Ų56.90%028%0.282CS..Hα-helixtrans-63.8-48.9175.5179.356.4000111.4I412 T418 T419 E420 R425 L426 I427 I439 R440 I449 V450I412-L423 HydrophobicContact CD1-CD1 3.98Å; T418-L423 HydrophobicContact CG2-CB 3.91Å; T419-L423 WeakPolarHBondContact O-CB 3.34Å; T419-L423 PolarHBondContact O-N 2.65Å; E420-L423 PolarHBondContact O-N 3.24Å; L423-R425 VanDerWaalsContact C-N 3.29Å; L423-R425 PolarHBondContact O-N 3.47Å; L423-L426 WeakPolarHBondContact O-CB 3.4Å; L423-L426 PolarHBondContact O-N 3.45Å; L423-L426 VanDerWaalsContact O-N 3.12Å; L423-I427 HydrophobicContact CD1-CD1 3.83Å; L423-I427 HydrophobicContact CD1-CG1 4.14Å; L423-I427 HydrophobicContact CG-CD1 3.79Å; L423-I427 HydrophobicContact CG-CG1 4.5Å; L423-I427 WeakPolarHBondContact O-CG1 3.3Å; L423-I427 PolarHBondContact O-N 3.03Å; L423-I439 HydrophobicContact CD1-CG2 3.83Å; L423-R440 HydrophobicContact CD2-CG 4.18Å; L423-I449 HydrophobicContact CD2-CG2 3.92Å; L423-V450 HydrophobicContact CD2-CG2 3.78Å
424D97.8Very high95.5Very high76 Ų7663 Ų6341%0.40632%0.315SS..Hα-helixtrans-59.7-41177.7-76.3-27.2000111.8E420 L426 I427 H428 R440E420-D424 PolarHBondContact O-N 2.63Å; D424-L426 PolarHBondContact O-N 3.16Å; D424-I427 PolarHBondContact O-N 3.04Å; D424-H428 VanDerWaalsContact O-CB 3.3Å; D424-H428 WeakPolarHBondContact O-CB 3.4Å; D424-H428 PolarHBondContact O-N 3.28Å; D424-R440 IonicContact OD1-CZ 2.79Å; D424-R440 IonicContact OD1-NH2 3.49Å; D424-R440 PolarHBondContact OD1-NH2 2.62Å
425R96.4Very high95.6Very high161 Ų16164 Ų6461%0.60832%0.318SS*.Hα-helixtrans-61.9-42.5174.5-76.1173.366.6-152.9-2.2112.4E421 N422 L423 N429E421-R425 WeakPolarHBondContact O-CB 3.39Å; E421-R425 WeakPolarHBondContact O-CD 3.42Å; E421-R425 WeakPolarHBondContact O-CG 3.45Å; E421-R425 PolarHBondContact O-N 2.93Å; E421-R425 VanDerWaalsContact O-N 3.09Å; N422-R425 PolarHBondContact O-N 2.98Å; L423-R425 VanDerWaalsContact C-N 3.29Å; L423-R425 PolarHBondContact O-N 3.47Å; R425-N429 VanDerWaalsContact O-CB 3.25Å; R425-N429 WeakPolarHBondContact O-CB 3.46Å; R425-N429 PolarHBondContact O-N 2.97Å; R425-N429 PolarHBondContact O-ND2 3.5Å; R425-N429 VanDerWaalsContact O-ND2 3.13Å
426L96.3Very high95.8Very high11 Ų1162.4 Ų62.46%0.05831%0.31CS..Hα-helixtrans-63.8-49.1176.7-75.5169.9000110.9M387 L390 L394 V408 Y411 N422 L423 D424 H428 N429 V430M387-L426 HydrophobicContact CE-CD1 4.22Å; M387-L426 HydrophobicContact CE-CD2 4.02Å; M387-L426 HydrophobicContact CE-CG 4.44Å; M387-L426 HydrophobicContact SD-CD2 4.04Å; L390-L426 HydrophobicContact CD2-CD2 4.27Å; L394-L426 HydrophobicContact CD1-CD2 3.83Å; V408-L426 HydrophobicContact CG1-CD1 4.36Å; Y411-L426 HydrophobicContact CD1-CD1 4.25Å; Y411-L426 HydrophobicContact CE1-CD1 4.06Å; N422-L426 WeakPolarHBondContact O-CG 3.29Å; N422-L426 PolarHBondContact O-N 2.87Å; L423-L426 WeakPolarHBondContact O-CB 3.4Å; L423-L426 PolarHBondContact O-N 3.45Å; L423-L426 VanDerWaalsContact O-N 3.12Å; D424-L426 PolarHBondContact O-N 3.16Å; L426-H428 VanDerWaalsContact C-N 3.32Å; L426-H428 PolarHBondContact O-N 2.98Å; L426-N429 PolarHBondContact O-N 3.2Å; L426-V430 VanDerWaalsContact O-CB 3.29Å; L426-V430 WeakPolarHBondContact O-CB 3.32Å; L426-V430 WeakPolarHBondContact O-CG2 3.46Å; L426-V430 PolarHBondContact O-N 3.29Å
427I96.8Very high96Very high8 Ų862.8 Ų62.84%0.04131%0.312CS..Hα-helixtrans-57.1-47.9179.5-70.6168.1000110.5L423 D424 K431 I432 E433 I439L423-I427 HydrophobicContact CD1-CD1 3.83Å; L423-I427 HydrophobicContact CD1-CG1 4.14Å; L423-I427 HydrophobicContact CG-CD1 3.79Å; L423-I427 HydrophobicContact CG-CG1 4.5Å; L423-I427 WeakPolarHBondContact O-CG1 3.3Å; L423-I427 PolarHBondContact O-N 3.03Å; D424-I427 PolarHBondContact O-N 3.04Å; I427-K431 PolarHBondContact O-N 3.35Å; I427-I432 HydrophobicContact CB-CG1 4.49Å; I427-I432 HydrophobicContact CG2-CG1 4.32Å; I427-I432 PolarHBondContact O-N 3.12Å; I427-I432 VanDerWaalsContact O-N 3.17Å; I427-E433 HydrophobicContact CG2-CB 4.43Å; I427-E433 HydrophobicContact CG2-CG 4.09Å; I427-I439 HydrophobicContact CG1-CD1 4.36Å
428H96Very high96.1Very high121 Ų12162.9 Ų62.956%0.5631%0.309SS*.Hα-helixtrans-67.6-46.7-178.3-174.857000113.1D424 L426 V430 K431 E433D424-H428 VanDerWaalsContact O-CB 3.3Å; D424-H428 WeakPolarHBondContact O-CB 3.4Å; D424-H428 PolarHBondContact O-N 3.28Å; L426-H428 VanDerWaalsContact C-N 3.32Å; L426-H428 PolarHBondContact O-N 2.98Å; H428-V430 VanDerWaalsContact C-N 3.25Å; H428-V430 PolarHBondContact O-N 3.36Å; H428-K431 PolarHBondContact O-N 2.84Å; H428-K431 VanDerWaalsContact O-N 3.17Å; H428-E433 WeakPolarHBondContact CA-OE1 3.45Å; H428-E433 IonicContact CE1-OE1 2.8Å; H428-E433 IonicContact CG-OE1 3.38Å; H428-E433 IonicContact ND1-OE1 3.69Å; H428-E433 PolarHBondContact ND1-OE1 2.92Å
429N92.9Very high96.3Very high117 Ų11762.1 Ų62.163%0.62630%0.304SS*.Hα-helixtrans-64.9-32.3-178.7-72.6-22.9000112.4R425 L426R425-N429 VanDerWaalsContact O-CB 3.25Å; R425-N429 WeakPolarHBondContact O-CB 3.46Å; R425-N429 PolarHBondContact O-N 2.97Å; R425-N429 PolarHBondContact O-ND2 3.5Å; R425-N429 VanDerWaalsContact O-ND2 3.13Å; L426-N429 PolarHBondContact O-N 3.2Å
430V93.4Very high96.4Very high11 Ų1161.2 Ų61.27%0.06729%0.292CS..Hα-helixtrans-84.5-16179.6-179.60000112L394 K404 L426 H428 I432L394-V430 HydrophobicContact CB-CG2 4.1Å; L394-V430 HydrophobicContact CD1-CG2 3.81Å; L394-V430 HydrophobicContact CD2-CG2 3.86Å; L394-V430 HydrophobicContact CG-CG2 4.12Å; K404-V430 HydrophobicContact CB-CG1 3.94Å; K404-V430 HydrophobicContact CD-CG1 3.83Å; K404-V430 HydrophobicContact CG-CG1 4.48Å; L426-V430 VanDerWaalsContact O-CB 3.29Å; L426-V430 WeakPolarHBondContact O-CB 3.32Å; L426-V430 WeakPolarHBondContact O-CG2 3.46Å; L426-V430 PolarHBondContact O-N 3.29Å; H428-V430 VanDerWaalsContact C-N 3.25Å; H428-V430 PolarHBondContact O-N 3.36Å; V430-I432 HydrophobicContact CB-CD1 4.29Å; V430-I432 HydrophobicContact CB-CG1 4.05Å; V430-I432 HydrophobicContact CG1-CD1 4.06Å; V430-I432 HydrophobicContact CG1-CG1 4.03Å; V430-I432 HydrophobicContact CG1-CG2 3.85Å
431K93.8Very high96.4Very high162 Ų16258 Ų5870%0.70428%0.277SS*.THydrogen-bonded Turntrans63.250.2-177.7-54.7179.3177.3-175.30113.1I427 H428 E433I427-K431 PolarHBondContact O-N 3.35Å; H428-K431 PolarHBondContact O-N 2.84Å; H428-K431 VanDerWaalsContact O-N 3.17Å; K431-E433 WeakPolarHBondContact CA-OE2 3.45Å
432I94.7Very high96.5Very high2 Ų252 Ų521%0.0125%0.249CC..  trans-121.129.9-179.654.3167.6000111.5N401 I405 I427 V430 D434 D435 S436 I439N401-I432 HydrophobicContact CB-CG2 4.04Å; I405-I432 HydrophobicContact CD1-CG2 4.32Å; I405-I432 HydrophobicContact CG1-CB 4.5Å; I405-I432 HydrophobicContact CG1-CD1 3.7Å; I405-I432 HydrophobicContact CG1-CG2 4.3Å; I427-I432 HydrophobicContact CB-CG1 4.49Å; I427-I432 HydrophobicContact CG2-CG1 4.32Å; I427-I432 PolarHBondContact O-N 3.12Å; I427-I432 VanDerWaalsContact O-N 3.17Å; V430-I432 HydrophobicContact CB-CD1 4.29Å; V430-I432 HydrophobicContact CB-CG1 4.05Å; V430-I432 HydrophobicContact CG1-CD1 4.06Å; V430-I432 HydrophobicContact CG1-CG1 4.03Å; V430-I432 HydrophobicContact CG1-CG2 3.85Å; I432-D434 VanDerWaalsContact C-N 3.28Å; I432-D434 PolarHBondContact O-N 2.85Å; I432-D435 HydrophobicContact CB-CB 4.45Å; I432-D435 CarbonylContact O-C 3.52Å; I432-D435 PolarHBondContact O-N 3.27Å; I432-S436 PolarHBondContact O-N 2.99Å; I432-I439 HydrophobicContact CD1-CD1 3.77Å
433E96.2Very high96.6Very high80 Ų8053.3 Ų53.337%0.37426%0.261SS..G310 helixtrans-54-44.2179.8-67.486.5163.200112I427 H428 K431 D435 S436I427-E433 HydrophobicContact CG2-CB 4.43Å; I427-E433 HydrophobicContact CG2-CG 4.09Å; H428-E433 WeakPolarHBondContact CA-OE1 3.45Å; H428-E433 IonicContact CE1-OE1 2.8Å; H428-E433 IonicContact CG-OE1 3.38Å; H428-E433 IonicContact ND1-OE1 3.69Å; H428-E433 PolarHBondContact ND1-OE1 2.92Å; K431-E433 WeakPolarHBondContact CA-OE2 3.45Å; E433-D435 PolarHBondContact O-N 2.87Å; E433-S436 VanDerWaalsContact O-CB 3.29Å; E433-S436 WeakPolarHBondContact O-CB 3.48Å; E433-S436 PolarHBondContact O-N 2.83Å; E433-S436 PolarHBondContact O-OG 2.84Å
434D95.4Very high96.6Very high142 Ų14256.1 Ų56.176%0.75927%0.274SS*.G310 helixtrans-67.6-17.7179.5-64.6-28.1000113.8I432 K578I432-D434 VanDerWaalsContact C-N 3.28Å; I432-D434 PolarHBondContact O-N 2.85Å; D434-K578 WeakPolarHBondContact O-CE 3.42Å; D434-K578 PolarHBondContact O-NZ 3.27Å
435D96.6Very high96.6Very high32 Ų3252.5 Ų52.517%0.17126%0.255CS..G310 helixtrans-110.57179.7-65.4-47.3000112.1I405 I432 E433 D437 M438 K578I405-D435 HydrophobicContact CD1-CB 3.65Å; I432-D435 HydrophobicContact CB-CB 4.45Å; I432-D435 CarbonylContact O-C 3.52Å; I432-D435 PolarHBondContact O-N 3.27Å; E433-D435 PolarHBondContact O-N 2.87Å; D435-D437 PolarHBondContact O-N 3.4Å; D435-D437 VanDerWaalsContact O-N 3.11Å; D435-M438 HydrophobicContact CB-CG 4.44Å; D435-M438 HydrophobicContact CB-SD 4.13Å; D435-M438 WeakPolarHBondContact O-CB 2.93Å; D435-M438 PolarHBondContact O-N 3.18Å; D435-K578 IonicContact OD1-NZ 2.81Å; D435-K578 PolarHBondContact OD1-NZ 3.04Å
436S97.2Very high96.6Very high27 Ų2746.1 Ų46.119%0.18924%0.239CC..THydrogen-bonded Turntrans-56.9-30.3-177.657.40000113.9I432 E433 M438 I439 R440I432-S436 PolarHBondContact O-N 2.99Å; E433-S436 VanDerWaalsContact O-CB 3.29Å; E433-S436 WeakPolarHBondContact O-CB 3.48Å; E433-S436 PolarHBondContact O-N 2.83Å; E433-S436 PolarHBondContact O-OG 2.84Å; S436-M438 PolarHBondContact O-N 3.47Å; S436-I439 PolarHBondContact O-N 2.81Å; S436-R440 PolarHBondContact O-N 3.08Å
437D97.9Very high96.6Very high32 Ų3246 Ų4617%0.17124%0.238CC..Hα-helixtrans-58.9-31.3172.7-73.1-37.2000112.7D435 I439 N441 K578 N581 K582D435-D437 PolarHBondContact O-N 3.4Å; D435-D437 VanDerWaalsContact O-N 3.11Å; D437-I439 PolarHBondContact O-N 3.07Å; D437-N441 VanDerWaalsContact O-CB 3.23Å; D437-N441 WeakPolarHBondContact O-CB 3.38Å; D437-N441 VanDerWaalsContact O-CG 3.31Å; D437-N441 PolarHBondContact O-N 2.89Å; D437-N441 VanDerWaalsContact O-N 3.13Å; D437-N441 PolarHBondContact O-ND2 3.41Å; D437-K578 HydrophobicContact CB-CG 3.88Å; D437-N581 PolarHBondContact OD1-ND2 3.33Å; D437-K582 WeakPolarHBondContact OD2-CE 3.5Å; D437-K582 IonicContact OD2-NZ 3.46Å; D437-K582 PolarHBondContact OD2-NZ 3.39Å
438M98.1Very high96.6Very high14 Ų1446.9 Ų46.97%0.06925%0.245CC..Hα-helixtrans-62.6-20.7175-66-174.1167.600112.4I405 D435 S436 W442 L574 D575 K578I405-M438 HydrophobicContact CD1-SD 3.85Å; I405-M438 HydrophobicContact CG2-CB 4.18Å; D435-M438 HydrophobicContact CB-CG 4.44Å; D435-M438 HydrophobicContact CB-SD 4.13Å; D435-M438 WeakPolarHBondContact O-CB 2.93Å; D435-M438 PolarHBondContact O-N 3.18Å; S436-M438 PolarHBondContact O-N 3.47Å; M438-W442 PolarHBondContact O-NE1 3.35Å; M438-L574 HydrophobicContact CB-CD2 4.48Å; M438-L574 HydrophobicContact CE-CB 4.32Å; M438-L574 HydrophobicContact CG-CB 4.4Å; M438-L574 HydrophobicContact SD-CB 3.97Å; M438-D575 WeakPolarHBondContact CE-OD1 3.45Å; M438-K578 HydrophobicContact CE-CB 4.35Å; M438-K578 HydrophobicContact CE-CD 3.8Å; M438-K578 HydrophobicContact CG-CB 3.75Å; M438-K578 HydrophobicContact CG-CD 4.08Å; M438-K578 HydrophobicContact CG-CG 3.97Å
439I98.5Very high96.7Very high0 Ų041.3 Ų41.30%022%0.219CC..Hα-helixtrans-99.1-51.2178.2-59.7168.2000110.7I405 V408 L409 I412 L423 I427 I432 S436 D437 N441 I449I405-I439 HydrophobicContact CG2-CG1 4.09Å; V408-I439 HydrophobicContact CB-CD1 4.49Å; V408-I439 HydrophobicContact CG1-CD1 3.92Å; L409-I439 HydrophobicContact CD2-CB 4.3Å; L409-I439 HydrophobicContact CD2-CG1 4.22Å; L409-I439 HydrophobicContact CD2-CG2 4.05Å; L409-I439 HydrophobicContact CG-CG1 4.38Å; I412-I439 HydrophobicContact CD1-CG2 3.67Å; L423-I439 HydrophobicContact CD1-CG2 3.83Å; I427-I439 HydrophobicContact CG1-CD1 4.36Å; I432-I439 HydrophobicContact CD1-CD1 3.77Å; S436-I439 PolarHBondContact O-N 2.81Å; D437-I439 PolarHBondContact O-N 3.07Å; I439-N441 PolarHBondContact O-N 3.41Å; I439-I449 HydrophobicContact CG2-CG2 4.28Å
440R98.3Very high96.9Very high59 Ų5938.5 Ų38.522%0.22321%0.206CC..Hα-helixtrans-68.3-36.6-171.7-67.5175.7173.3-77.33113.2E420 L423 D424 S436 W442 S443E420-R440 IonicContact OE1-CZ 3.11Å; E420-R440 IonicContact OE1-NH1 3.94Å; E420-R440 PolarHBondContact OE1-NH1 3.14Å; E420-R440 IonicContact OE1-NH2 3.83Å; E420-R440 PolarHBondContact OE1-NH2 2.73Å; E420-R440 IonicContact OE2-NH1 2.85Å; E420-R440 PolarHBondContact OE2-NH1 2.85Å; L423-R440 HydrophobicContact CD2-CG 4.18Å; D424-R440 IonicContact OD1-CZ 2.79Å; D424-R440 IonicContact OD1-NH2 3.49Å; D424-R440 PolarHBondContact OD1-NH2 2.62Å; S436-R440 PolarHBondContact O-N 3.08Å; R440-W442 PolarHBondContact O-N 3.36Å; R440-S443 WeakPolarHBondContact O-CB 3.48Å; R440-S443 PolarHBondContact O-N 3Å; R440-S443 PolarHBondContact O-OG 3.34Å
441N98.4Very high96.9Very high5 Ų539.3 Ų39.33%0.02721%0.212CC..G310 helixtrans-72.3-10.1-173.5-69.1-11.8000113.9D437 I439 S443 H444 I577 L580 N581D437-N441 VanDerWaalsContact O-CB 3.23Å; D437-N441 WeakPolarHBondContact O-CB 3.38Å; D437-N441 VanDerWaalsContact O-CG 3.31Å; D437-N441 PolarHBondContact O-N 2.89Å; D437-N441 VanDerWaalsContact O-N 3.13Å; D437-N441 PolarHBondContact O-ND2 3.41Å; I439-N441 PolarHBondContact O-N 3.41Å; N441-S443 PolarHBondContact O-N 3.09Å; N441-H444 VanDerWaalsContact O-CB 3.32Å; N441-H444 WeakPolarHBondContact O-CB 3.27Å; N441-H444 PolarHBondContact O-N 3.09Å; N441-I577 HydrophobicContact CB-CG2 3.72Å; N441-I577 VanDerWaalsContact CB-O 3.3Å; N441-I577 WeakPolarHBondContact CB-O 3.34Å; N441-I577 PolarHBondContact ND2-O 3.07Å; N441-L580 HydrophobicContact CB-CB 4.3Å; N441-L580 HydrophobicContact CB-CD1 4.27Å; N441-N581 VanDerWaalsContact ND2-CG 3.31Å; N441-N581 PolarHBondContact ND2-OD1 3.02Å; N441-N581 VanDerWaalsContact ND2-OD1 3.1Å; N441-N581 PolarHBondContact OD1-ND2 3.35Å
442W98.4Very high96.7Very high0 Ų038 Ų380%022%0.219CC..G310 helixtrans-57.1-26.6168.9-82.394.9000113.1P244 T247 V248 L409 F413 M438 R440 H444 L445 V447 I449 L573 I577P244-W442 HydrophobicContact CB-CE3 3.9Å; P244-W442 HydrophobicContact CB-CH2 4.11Å; P244-W442 HydrophobicContact CB-CZ3 3.49Å; P244-W442 VanDerWaalsContact CB-CZ3 3.49Å; T247-W442 VanDerWaalsContact OG1-CH2 3.22Å; T247-W442 WeakPolarHBondContact OG1-CH2 3.48Å; V248-W442 HydrophobicContact CG1-CZ2 3.91Å; L409-W442 VanDerWaalsContact CD2-CD1 3.49Å; L409-W442 HydrophobicContact CD2-CG 4.3Å; F413-W442 HydrophobicContact CE1-CD2 4.25Å; F413-W442 HydrophobicContact CE1-CE3 4.47Å; F413-W442 HydrophobicContact CE1-CG 4.35Å; F413-W442 AromaticContact CZ-CD2 3.71Å; F413-W442 HydrophobicContact CZ-CD2 3.71Å; F413-W442 AromaticContact CZ-CE2 3.77Å; F413-W442 HydrophobicContact CZ-CE3 4.02Å; F413-W442 HydrophobicContact CZ-CG 4.13Å; F413-W442 HydrophobicContact CZ-CH2 4.44Å; F413-W442 HydrophobicContact CZ-CZ2 4.14Å; F413-W442 HydrophobicContact CZ-CZ3 4.37Å; M438-W442 PolarHBondContact O-NE1 3.35Å; R440-W442 PolarHBondContact O-N 3.36Å; W442-H444 PolarHBondContact O-N 3.34Å; W442-L445 HydrophobicContact CE3-CD2 4.07Å; W442-L445 HydrophobicContact CZ3-CD2 3.97Å; W442-L445 WeakPolarHBondContact O-CA 3.38Å; W442-L445 WeakPolarHBondContact O-CB 3.43Å; W442-L445 PolarHBondContact O-N 2.9Å; W442-V447 HydrophobicContact CB-CB 4.31Å; W442-V447 HydrophobicContact CE3-CB 4.27Å; W442-V447 HydrophobicContact CE3-CG2 3.92Å; W442-V447 HydrophobicContact CZ3-CG2 4.45Å; W442-V447 WeakPolarHBondContact O-CB 3.29Å; W442-V447 PolarHBondContact O-N 3.47Å; W442-I449 HydrophobicContact CB-CD1 3.64Å; W442-I449 HydrophobicContact CB-CG1 3.73Å; W442-I449 HydrophobicContact CG-CD1 4.37Å; W442-L573 HydrophobicContact CH2-CD2 3.84Å; W442-L573 HydrophobicContact CZ2-CD2 4.06Å; W442-I577 HydrophobicContact CD2-CD1 3.72Å; W442-I577 HydrophobicContact CE3-CD1 4.23Å; W442-I577 HydrophobicContact CG-CD1 4.28Å; W442-I577 HydrophobicContact CH2-CD1 3.8Å; W442-I577 HydrophobicContact CZ2-CD1 3.25Å; W442-I577 HydrophobicContact CZ3-CD1 4.27Å
443S97.7Very high96.4Very high60 Ų6041.4 Ų41.442%0.4224%0.244SC..G310 helixtrans-56.6-32171.961.10000113R440 N441 L445 G446 V447R440-S443 WeakPolarHBondContact O-CB 3.48Å; R440-S443 PolarHBondContact O-N 3Å; R440-S443 PolarHBondContact O-OG 3.34Å; N441-S443 PolarHBondContact O-N 3.09Å; S443-L445 PolarHBondContact O-N 3.21Å; S443-G446 PolarHBondContact O-N 2.95Å; S443-V447 WeakPolarHBondContact CA-O 3.24Å
444H97.9Very high95.6Very high58 Ų5847.1 Ų47.127%0.26927%0.27SS..G310 helixtrans-72.1-18.2176.2-58.3-46.4000113.6Y160 N441 W442 L580Y160-H444 WeakPolarHBondContact O-CB 3.47Å; N441-H444 VanDerWaalsContact O-CB 3.32Å; N441-H444 WeakPolarHBondContact O-CB 3.27Å; N441-H444 PolarHBondContact O-N 3.09Å; W442-H444 PolarHBondContact O-N 3.34Å; H444-L580 HydrophobicContact CB-CD1 4.44Å
445L98Very high94.9Very high1 Ų145.7 Ų45.71%0.00526%0.259CS..G310 helixtrans-86.75170.3-76.270.2000111.7F156 Y160 R240 W442 S443 V447 L580F156-L445 HydrophobicContact CE2-CD2 4.06Å; F156-L445 HydrophobicContact CZ-CD1 4.18Å; F156-L445 HydrophobicContact CZ-CD2 4.03Å; Y160-L445 HydrophobicContact CD1-CD1 4.45Å; Y160-L445 HydrophobicContact CD1-CG 4.06Å; Y160-L445 HydrophobicContact CD2-CG 4.37Å; Y160-L445 HydrophobicContact CE1-CG 4.42Å; Y160-L445 HydrophobicContact CG-CD1 4.14Å; Y160-L445 HydrophobicContact CG-CG 4.07Å; R240-L445 HydrophobicContact CB-CD2 4.22Å; R240-L445 HydrophobicContact CG-CD2 4.16Å; W442-L445 HydrophobicContact CE3-CD2 4.07Å; W442-L445 HydrophobicContact CZ3-CD2 3.97Å; W442-L445 WeakPolarHBondContact O-CA 3.38Å; W442-L445 WeakPolarHBondContact O-CB 3.43Å; W442-L445 PolarHBondContact O-N 2.9Å; S443-L445 PolarHBondContact O-N 3.21Å; L445-V447 VanDerWaalsContact C-N 3.3Å; L445-V447 HydrophobicContact CB-CG2 4.28Å; L445-L580 HydrophobicContact CD1-CD1 3.5Å; L445-L580 VanDerWaalsContact CD1-CD1 3.5Å
446G96.3Very high94.3Very high26 Ų2648.7 Ų48.727%0.26829%0.288SS..THydrogen-bonded Turntrans76.616.2-176.100000113.7P200 S443P200-G446 WeakPolarHBondContact CG-O 3.26Å; S443-G446 PolarHBondContact O-N 2.95Å
447V96.8Very high93.7Very high8 Ų852.2 Ų52.25%0.04830%0.3CS..  trans-92.2126.3178.3-179.40000109.5G241 P244 F413 W442 S443 L445 I449G241-V447 WeakPolarHBondContact O-CG2 3.32Å; P244-V447 HydrophobicContact CB-CG1 4.05Å; P244-V447 HydrophobicContact CB-CG2 4.01Å; P244-V447 HydrophobicContact CG-CG1 3.87Å; P244-V447 HydrophobicContact CG-CG2 4.11Å; F413-V447 HydrophobicContact CD1-CG1 3.75Å; F413-V447 HydrophobicContact CE1-CG1 3.54Å; F413-V447 HydrophobicContact CZ-CG1 4.49Å; W442-V447 HydrophobicContact CB-CB 4.31Å; W442-V447 HydrophobicContact CE3-CB 4.27Å; W442-V447 HydrophobicContact CE3-CG2 3.92Å; W442-V447 HydrophobicContact CZ3-CG2 4.45Å; W442-V447 WeakPolarHBondContact O-CB 3.29Å; W442-V447 PolarHBondContact O-N 3.47Å; S443-V447 WeakPolarHBondContact CA-O 3.24Å; L445-V447 VanDerWaalsContact C-N 3.3Å; L445-V447 HydrophobicContact CB-CG2 4.28Å; V447-I449 PolarHBondContact O-N 3.47Å
448P95.9Very high93Very high27 Ų2754.5 Ų54.518%0.17532%0.317CS..  trans-70113.7-177.226.8-33.2000111.5N416 P451N416-P448 WeakPolarHBondContact OD1-CG 3.08Å; P448-P451 HydrophobicContact CB-CB 3.95Å; P448-P451 HydrophobicContact CB-CG 4.08Å
449I97.4Very high92.5Very high5 Ų559.6 Ų59.63%0.02635%0.351CS..SBendtrans-101.9-58.1173.3-58.2-59000110.6I412 F413 G417 T418 L423 I439 W442 V447 P451I412-I449 HydrophobicContact CG2-CD1 3.84Å; F413-I449 HydrophobicContact CE1-CD1 3.94Å; G417-I449 CarbonylContact C-O 3.58Å; G417-I449 WeakPolarHBondContact CA-O 3.28Å; T418-I449 WeakPolarHBondContact CG2-O 3.46Å; T418-I449 PolarHBondContact N-O 2.91Å; L423-I449 HydrophobicContact CD2-CG2 3.92Å; I439-I449 HydrophobicContact CG2-CG2 4.28Å; W442-I449 HydrophobicContact CB-CD1 3.64Å; W442-I449 HydrophobicContact CB-CG1 3.73Å; W442-I449 HydrophobicContact CG-CD1 4.37Å; V447-I449 PolarHBondContact O-N 3.47Å; I449-P451 VanDerWaalsContact C-CD 3.49Å; I449-P451 WeakPolarHBondContact O-CD 3.49Å
450V97.1Very high92.2Very high57 Ų5763.3 Ų63.335%0.34537%0.365SS..SBendtrans-122.673.5170.9-172.70000108.6T418 E420 L423T418-V450 WeakPolarHBondContact O-CA 3.46Å; E420-V450 HydrophobicContact CB-CG1 4.27Å; E420-V450 WeakPolarHBondContact OE2-CG2 3.36Å; L423-V450 HydrophobicContact CD2-CG2 3.78Å
451P94.2Very high92Very high29 Ų2963.4 Ų63.419%0.18837%0.367CS..  trans-70.9146.4-17731.7-35.9000110.7P448 I449 S453P448-P451 HydrophobicContact CB-CB 3.95Å; P448-P451 HydrophobicContact CB-CG 4.08Å; I449-P451 VanDerWaalsContact C-CD 3.49Å; I449-P451 WeakPolarHBondContact O-CD 3.49Å; P451-S453 WeakPolarHBondContact CB-O 3.43Å; P451-S453 PolarHBondContact O-N 3.23Å
452P89.4Confident91.6Very high134 Ų13469.6 Ų69.687%0.8740%0.4SS*.SBendtrans-68.3-20.7179.228.2-35.7000113.2
453S88.2Confident91.3Very high74 Ų7470.3 Ų70.352%0.51740%0.403SS..SBendtrans-148153.1175.655.90000109.6P451 Q455P451-S453 WeakPolarHBondContact CB-O 3.43Å; P451-S453 PolarHBondContact O-N 3.23Å; S453-Q455 PolarHBondContact O-N 3.17Å
454Q80.8Confident90.8Very high199 Ų19970.6 Ų70.693%0.9341%0.405SS*.PPolyproline II helixtrans-65.2121.5177.2-72-178.6-3.100110.1
455Q80.3Confident90.3Very high112 Ų11272.7 Ų72.752%0.52343%0.432SS..PPolyproline II helixtrans-97.9148.5174.5-65.4-177.4100110N416 S453N416-Q455 PolarHBondContact ND2-O 2.93Å; S453-Q455 PolarHBondContact O-N 3.17Å
456A83.2Confident89.7Confident96 Ų9677.8 Ų77.879%0.79346%0.456SS*.PPolyproline II helixtrans-67.4142.7170.400000109.9
457K84.1Confident89.2Confident100 Ų10080 Ų8044%0.43546%0.46SS..PPolyproline II helixtrans-71.1148.2173-69.9-178.2179.6-1790110.6G414 N416G414-K457 WeakPolarHBondContact O-CE 3.29Å; G414-K457 PolarHBondContact O-NZ 3.47Å; N416-K457 HydrophobicContact CB-CG 3.84Å
458P83.5Confident88.8Confident80 Ų8085.1 Ų85.152%0.51949%0.491SS..PPolyproline II helixtrans-56.3136.2167.1-21.932.9000110.6F477P458-F477 HydrophobicContact CB-CE1 4.03Å; P458-F477 HydrophobicContact CB-CZ 4.45Å
459P88.4Confident88.7Confident122 Ų12287 Ų8779%0.79250%0.496SS*.PPolyproline II helixtrans-65.5149174.629-34.2000110.4
460R91.6Very high88.5Confident77 Ų7792.9 Ų92.929%0.29152%0.524SS..  trans-122.6151.1173-70.8179.472.3-118.6-2.2109.2L374 W474 T475 F477L374-R460 VanDerWaalsContact CD2-NH1 3.25Å; R460-W474 VanDerWaalsContact CZ-CZ3 3.5Å; R460-T475 PolarHBondContact NH2-O 3.25Å; R460-F477 HydrophobicContact CB-CE1 4.46Å; R460-F477 HydrophobicContact CG-CD1 3.79Å; R460-F477 HydrophobicContact CG-CE1 3.1Å; R460-F477 HydrophobicContact CG-CE2 4.19Å; R460-F477 HydrophobicContact CG-CZ 3.36Å
461K94Very high88.4Confident61 Ų6192.1 Ų92.127%0.26552%0.517SS..  trans-66141.2169.6-66.4-176.8-175.9-179.20109.9R463 D480 E483 D484K461-R463 PolarHBondContact O-N 3.04Å; K461-D480 HydrophobicContact CD-CB 4.18Å; K461-D480 HydrophobicContact CG-CB 4.24Å; K461-D480 PolarHBondContact N-OD2 3.41Å; K461-E483 WeakPolarHBondContact CD-OE2 3.47Å; K461-E483 VanDerWaalsContact NZ-CB 3.31Å; K461-E483 IonicContact NZ-OE2 3.68Å; K461-E483 PolarHBondContact NZ-OE2 2.68Å; K461-D484 WeakPolarHBondContact CE-OD1 3.28Å; K461-D484 IonicContact NZ-OD1 2.63Å; K461-D484 PolarHBondContact NZ-OD1 3.41Å
462D91Very high88.5Confident136 Ų13692.1 Ų92.173%0.72752%0.518SS*.  trans-72.4120.7169.9-1786.7000108.9S464D462-S464 VanDerWaalsContact OD1-CB 3.27Å; D462-S464 WeakPolarHBondContact OD1-CB 3.46Å; D462-S464 PolarHBondContact OD1-N 2.89Å; D462-S464 PolarHBondContact OD1-OG 2.98Å; D462-S464 PolarHBondContact OD2-OG 3.01Å
463R92.5Very high88.8Confident15 Ų1586.2 Ų86.26%0.05748%0.479CS..  trans-121.714.7-179-64.6-176.4178-84.21.7112.2K461 A465 E466 T475 D480 E483K461-R463 PolarHBondContact O-N 3.04Å; R463-A465 PolarHBondContact O-N 2.96Å; R463-A465 VanDerWaalsContact O-N 3.09Å; R463-E466 IonicContact NH1-OE1 3.88Å; R463-E466 PolarHBondContact NH1-OE1 3.42Å; R463-E466 IonicContact NH1-OE2 3.51Å; R463-E466 PolarHBondContact NH1-OE2 3.43Å; R463-E466 WeakPolarHBondContact O-CB 3.47Å; R463-E466 PolarHBondContact O-N 2.95Å; R463-T475 WeakPolarHBondContact CD-OG1 3.38Å; R463-D480 IonicContact CZ-OD1 3.34Å; R463-D480 VanDerWaalsContact CZ-OD1 3.29Å; R463-D480 IonicContact NE-OD1 3.98Å; R463-D480 PolarHBondContact NE-OD1 2.94Å; R463-D480 IonicContact NH2-OD1 3.25Å; R463-D480 PolarHBondContact NH2-OD1 3.46Å; R463-E483 IonicContact CZ-OE1 2.71Å; R463-E483 IonicContact CZ-OE2 3.72Å; R463-E483 IonicContact NH1-OE1 3.22Å; R463-E483 PolarHBondContact NH1-OE1 3.49Å; R463-E483 IonicContact NH2-OE1 3.3Å; R463-E483 PolarHBondContact NH2-OE1 3.29Å; R463-E483 IonicContact NH2-OE2 3.6Å; R463-E483 PolarHBondContact NH2-OE2 3.35Å
464S86.5Confident89.2Confident66 Ų6683.6 Ų83.646%0.46246%0.458SS..G310 helixtrans-53.6-33.3-178.5530000113.3D462 E466 E467D462-S464 VanDerWaalsContact OD1-CB 3.27Å; D462-S464 WeakPolarHBondContact OD1-CB 3.46Å; D462-S464 PolarHBondContact OD1-N 2.89Å; D462-S464 PolarHBondContact OD1-OG 2.98Å; D462-S464 PolarHBondContact OD2-OG 3.01Å; S464-E466 VanDerWaalsContact C-N 3.31Å; S464-E466 PolarHBondContact O-N 3.41Å; S464-E467 PolarHBondContact O-N 3.46Å
465A87Confident90Very high102 Ų10275.1 Ų75.184%0.84342%0.419SS*.G310 helixtrans-72.2-18.5176.800000114.7R463R463-A465 PolarHBondContact O-N 2.96Å; R463-A465 VanDerWaalsContact O-N 3.09Å
466E86.4Confident90.8Very high108 Ų10869.8 Ų69.851%0.50540%0.395SS..G310 helixtrans-90.7-11.3177.9-62.2174.5-156.300112.1R463 S464 T468 K479R463-E466 IonicContact NH1-OE1 3.88Å; R463-E466 PolarHBondContact NH1-OE1 3.42Å; R463-E466 IonicContact NH1-OE2 3.51Å; R463-E466 PolarHBondContact NH1-OE2 3.43Å; R463-E466 WeakPolarHBondContact O-CB 3.47Å; R463-E466 PolarHBondContact O-N 2.95Å; S464-E466 VanDerWaalsContact C-N 3.31Å; S464-E466 PolarHBondContact O-N 3.41Å; E466-T468 PolarHBondContact O-N 2.94Å; E466-K479 IonicContact OE2-NZ 2.81Å
467E84.9Confident91.5Very high73 Ų7366.7 Ų66.734%0.34136%0.363SS..  trans-69.7113.8-175.5-66.4178.8-167.800111.3S464 R473S464-E467 PolarHBondContact O-N 3.46Å; E467-R473 HydrophobicContact CG-CB 4.19Å; E467-R473 HydrophobicContact CG-CG 4.23Å; E467-R473 VanDerWaalsContact OE2-CD 3.23Å; E467-R473 WeakPolarHBondContact OE2-CD 3.44Å
468T88.8Confident92.1Very high115 Ų11561.9 Ų61.971%0.70634%0.342SS*.  trans-107.9-24.7179.145.60000112.9E466E466-T468 PolarHBondContact O-N 2.94Å
469F93.7Very high92.8Very high65 Ų6559.1 Ų59.129%0.28532%0.322SS..BIsolated β-bridgetrans-127.9124.3-176.7-59.7-77.7000110.5H296 A298 V299 L471 S472 R473H296-F469 HydrophobicContact CB-CD2 4.1Å; H296-F469 HydrophobicContact CB-CE2 3.64Å; H296-F469 HydrophobicContact CB-CZ 4.16Å; H296-F469 AromaticContact CD2-CD2 3.77Å; H296-F469 AromaticContact CE1-CD1 3.64Å; H296-F469 AromaticContact CE1-CE1 3.95Å; H296-F469 AromaticContact CE1-CG 3.7Å; H296-F469 AromaticContact CG-CD2 3.64Å; H296-F469 AromaticContact CG-CE2 3.57Å; H296-F469 AromaticContact CG-CZ 3.96Å; H296-F469 AromaticContact ND1-CD1 3.79Å; H296-F469 AromaticContact ND1-CD2 3.81Å; H296-F469 AromaticContact ND1-CE1 3.65Å; H296-F469 AromaticContact ND1-CE2 3.68Å; H296-F469 AromaticContact ND1-CG 3.87Å; H296-F469 AromaticContact ND1-CZ 3.6Å; H296-F469 AromaticContact NE2-CG 3.8Å; A298-F469 HydrophobicContact CB-CE1 3.82Å; A298-F469 HydrophobicContact CB-CZ 4.26Å; V299-F469 HydrophobicContact CG2-CZ 4.06Å; F469-L471 PolarHBondContact O-N 3.1Å; F469-S472 CarbonylContact O-C 3.57Å; F469-S472 PolarHBondContact O-N 2.98Å; F469-R473 WeakPolarHBondContact O-CG 3.42Å
470Q93.1Very high93.3Very high130 Ų13053.8 Ų53.861%0.60729%0.287SS*.THydrogen-bonded Turntrans-59.3-31.2-178.2-67.6-177.5-28.100113.6A378 R473A378-Q470 HydrophobicContact CB-CB 4.22Å; A378-Q470 HydrophobicContact CB-CG 4.15Å; Q470-R473 WeakPolarHBondContact O-CD 3.36Å; Q470-R473 WeakPolarHBondContact O-CG 3.37Å; Q470-R473 PolarHBondContact O-NE 3.47Å; Q470-R473 VanDerWaalsContact O-NE 3.08Å
471L95.5Very high93.6Very high40 Ų4051.1 Ų51.121%0.20928%0.278CS..THydrogen-bonded Turntrans-91.57.2179-57.6-178000113.4L252 F358 E363 C366 K367 F469L252-L471 HydrophobicContact CD1-CB 3.86Å; F358-L471 HydrophobicContact CZ-CD1 3.81Å; E363-L471 HydrophobicContact CG-CD1 4.15Å; C366-L471 HydrophobicContact CB-CB 4.45Å; K367-L471 HydrophobicContact CB-CD2 3.74Å; K367-L471 HydrophobicContact CG-CD2 4.36Å; F469-L471 PolarHBondContact O-N 3.1Å
472S95.8Very high93.7Very high30 Ų3048.2 Ų48.221%0.2127%0.265CS..BIsolated β-bridgetrans-147.971.2-179.8-69.40000110.3L252 H296 F469L252-S472 WeakPolarHBondContact CB-OG 3.21Å; L252-S472 WeakPolarHBondContact CG-OG 3.46Å; H296-S472 PolarHBondContact NE2-OG 3.31Å; F469-S472 CarbonylContact O-C 3.57Å; F469-S472 PolarHBondContact O-N 2.98Å
473R95.7Very high94Very high9 Ų943.1 Ų43.13%0.03424%0.237CC..  trans-107.5-27.6-176.3-60.2-175.4-69.4146.8-0.4111.8D371 L374 T376 D377 E467 F469 Q470 T475D371-R473 IonicContact OD1-NH2 2.76Å; D371-R473 PolarHBondContact OD1-NH2 3.16Å; L374-R473 HydrophobicContact CD1-CB 3.44Å; L374-R473 VanDerWaalsContact CD1-CB 3.44Å; T376-R473 PolarHBondContact O-NH2 3.41Å; D377-R473 VanDerWaalsContact C-NH2 3.3Å; D377-R473 PolarHBondContact O-NH1 3.01Å; E467-R473 HydrophobicContact CG-CB 4.19Å; E467-R473 HydrophobicContact CG-CG 4.23Å; E467-R473 VanDerWaalsContact OE2-CD 3.23Å; E467-R473 WeakPolarHBondContact OE2-CD 3.44Å; F469-R473 WeakPolarHBondContact O-CG 3.42Å; Q470-R473 WeakPolarHBondContact O-CD 3.36Å; Q470-R473 WeakPolarHBondContact O-CG 3.37Å; Q470-R473 PolarHBondContact O-NE 3.47Å; Q470-R473 VanDerWaalsContact O-NE 3.08Å; R473-T475 PolarHBondContact O-N 3.37Å
474W96.2Very high94.2Very high20 Ų2044.2 Ų44.28%0.07624%0.244CC..  trans-61.1134.1175.4-176.4-100.3000111.9V245 S246 L249 A373 L374 R460 F477V245-W474 HydrophobicContact CB-CH2 3.78Å; V245-W474 HydrophobicContact CB-CZ2 3.46Å; V245-W474 VanDerWaalsContact CB-CZ2 3.46Å; V245-W474 HydrophobicContact CG1-CD2 3.72Å; V245-W474 VanDerWaalsContact CG1-CE2 3.42Å; V245-W474 HydrophobicContact CG1-CE3 3.97Å; V245-W474 HydrophobicContact CG1-CG 4.42Å; V245-W474 HydrophobicContact CG1-CH2 3.68Å; V245-W474 HydrophobicContact CG1-CZ2 3.42Å; V245-W474 VanDerWaalsContact CG1-CZ2 3.42Å; V245-W474 HydrophobicContact CG1-CZ3 3.94Å; V245-W474 HydrophobicContact CG2-CH2 4.01Å; V245-W474 HydrophobicContact CG2-CZ2 4.18Å; S246-W474 PolarHBondContact OG-NE1 3.4Å; L249-W474 HydrophobicContact CD1-CB 4.39Å; L249-W474 HydrophobicContact CD2-CB 3.66Å; L249-W474 HydrophobicContact CD2-CG 3.85Å; A373-W474 HydrophobicContact CB-CD2 4.3Å; A373-W474 HydrophobicContact CB-CE3 3.71Å; A373-W474 HydrophobicContact CB-CZ3 4.13Å; A373-W474 WeakPolarHBondContact O-CZ3 3.17Å; L374-W474 HydrophobicContact CD2-CE3 3.81Å; L374-W474 HydrophobicContact CD2-CZ3 4.29Å; L374-W474 HydrophobicContact CG-CE3 4.35Å; R460-W474 VanDerWaalsContact CZ-CZ3 3.5Å; W474-F477 HydrophobicContact CH2-CD2 4.06Å; W474-F477 AromaticContact CH2-CE2 3.56Å; W474-F477 HydrophobicContact CH2-CE2 3.56Å; W474-F477 HydrophobicContact CH2-CZ 4.41Å; W474-F477 AromaticContact CZ2-CD2 3.77Å; W474-F477 HydrophobicContact CZ2-CD2 3.77Å; W474-F477 AromaticContact CZ2-CE2 3.74Å; W474-F477 HydrophobicContact CZ2-CE2 3.74Å
475T97Very high94.6Very high20 Ų2041.1 Ų41.112%0.12322%0.222CC..  trans-121.7125.9171.6-630000108.3R460 R463 R473 K479R460-T475 PolarHBondContact NH2-O 3.25Å; R463-T475 WeakPolarHBondContact CD-OG1 3.38Å; R473-T475 PolarHBondContact O-N 3.37Å; T475-K479 HydrophobicContact CG2-CB 4Å; T475-K479 HydrophobicContact CG2-CD 3.57Å; T475-K479 HydrophobicContact CG2-CG 4.38Å
476P97.8Very high94.9Very high1 Ų136.3 Ų36.31%0.00618%0.183CC..  trans-54.7138.9178.4-27.935.2000113.3D243 S246 I478 K479 E544D243-P476 WeakPolarHBondContact OD2-CA 3.45Å; S246-P476 VanDerWaalsContact OG-CA 3.27Å; S246-P476 WeakPolarHBondContact OG-CA 3.31Å; S246-P476 WeakPolarHBondContact OG-CB 3.34Å; P476-I478 HydrophobicContact CB-CG2 4.26Å; P476-I478 PolarHBondContact O-N 3.19Å; P476-I478 VanDerWaalsContact O-N 3.11Å; P476-K479 WeakPolarHBondContact O-CB 3.48Å; P476-K479 PolarHBondContact O-N 3.3Å; P476-E544 HydrophobicContact CB-CG 4.24Å
477F97.4Very high95.2Very high30 Ų3033.9 Ų33.913%0.13217%0.173CC..Hα-helixtrans-58.3-28.2180-84.4-91.2000112.5F242 D243 P458 R460 W474 K479 D480 I481F242-F477 HydrophobicContact CD2-CB 4.36Å; F242-F477 HydrophobicContact CE2-CB 4.21Å; D243-F477 HydrophobicContact CB-CB 4.06Å; D243-F477 HydrophobicContact CB-CD2 4.11Å; D243-F477 PolarHBondContact OD2-N 3.12Å; P458-F477 HydrophobicContact CB-CE1 4.03Å; P458-F477 HydrophobicContact CB-CZ 4.45Å; R460-F477 HydrophobicContact CB-CE1 4.46Å; R460-F477 HydrophobicContact CG-CD1 3.79Å; R460-F477 HydrophobicContact CG-CE1 3.1Å; R460-F477 HydrophobicContact CG-CE2 4.19Å; R460-F477 HydrophobicContact CG-CZ 3.36Å; W474-F477 HydrophobicContact CH2-CD2 4.06Å; W474-F477 AromaticContact CH2-CE2 3.56Å; W474-F477 HydrophobicContact CH2-CE2 3.56Å; W474-F477 HydrophobicContact CH2-CZ 4.41Å; W474-F477 AromaticContact CZ2-CD2 3.77Å; W474-F477 HydrophobicContact CZ2-CD2 3.77Å; W474-F477 AromaticContact CZ2-CE2 3.74Å; W474-F477 HydrophobicContact CZ2-CE2 3.74Å; F477-K479 PolarHBondContact O-N 3.01Å; F477-D480 WeakPolarHBondContact O-CB 3.13Å; F477-D480 PolarHBondContact O-N 2.97Å; F477-D480 VanDerWaalsContact O-N 3.14Å; F477-I481 WeakPolarHBondContact O-CG1 3.39Å; F477-I481 PolarHBondContact O-N 3.39Å; F477-I481 VanDerWaalsContact O-N 3.13Å
478I98.1Very high95.4Very high0 Ų035 Ų350%018%0.181CC..Hα-helixtrans-60.3-28.3179.8-147.5175.1000112.2F242 P476 I481 M482 I534 V536 E544 C547 I562F242-I478 HydrophobicContact CE2-CB 3.88Å; F242-I478 HydrophobicContact CE2-CG1 4.11Å; F242-I478 HydrophobicContact CZ-CB 3.88Å; F242-I478 HydrophobicContact CZ-CD1 3.96Å; F242-I478 HydrophobicContact CZ-CG1 3.93Å; P476-I478 HydrophobicContact CB-CG2 4.26Å; P476-I478 PolarHBondContact O-N 3.19Å; P476-I478 VanDerWaalsContact O-N 3.11Å; I478-I481 PolarHBondContact O-N 3.05Å; I478-M482 HydrophobicContact CD1-CE 3.94Å; I478-M482 HydrophobicContact CG1-CE 3.93Å; I478-M482 HydrophobicContact CG2-CE 4Å; I478-M482 HydrophobicContact CG2-SD 4.44Å; I478-M482 WeakPolarHBondContact O-CB 3.34Å; I478-M482 WeakPolarHBondContact O-CG 3.24Å; I478-M482 PolarHBondContact O-N 3.28Å; I478-I534 HydrophobicContact CD1-CG2 4.02Å; I478-V536 HydrophobicContact CD1-CG2 4Å; I478-E544 HydrophobicContact CB-CG 4.42Å; I478-E544 HydrophobicContact CD1-CB 4.44Å; I478-E544 HydrophobicContact CG2-CB 3.93Å; I478-E544 HydrophobicContact CG2-CG 3.83Å; I478-C547 HydrophobicContact CG2-CB 3.94Å; I478-I562 HydrophobicContact CD1-CD1 3.58Å
479K98.2Very high95.7Very high22 Ų2237.9 Ų37.910%0.09618%0.179CC..Hα-helixtrans-65.4-46.6176.8-165.8177.6177.9174.40111E466 T475 P476 F477 I481 M482 E483 C547 E550 V551E466-K479 IonicContact OE2-NZ 2.81Å; T475-K479 HydrophobicContact CG2-CB 4Å; T475-K479 HydrophobicContact CG2-CD 3.57Å; T475-K479 HydrophobicContact CG2-CG 4.38Å; P476-K479 WeakPolarHBondContact O-CB 3.48Å; P476-K479 PolarHBondContact O-N 3.3Å; F477-K479 PolarHBondContact O-N 3.01Å; K479-I481 VanDerWaalsContact C-N 3.28Å; K479-I481 PolarHBondContact O-N 2.93Å; K479-M482 PolarHBondContact O-N 3.32Å; K479-E483 WeakPolarHBondContact O-CG 3.29Å; K479-E483 PolarHBondContact O-N 2.65Å; K479-C547 HydrophobicContact CB-CB 4.03Å; K479-C547 HydrophobicContact CG-CB 4.33Å; K479-E550 WeakPolarHBondContact CE-OE2 3.41Å; K479-E550 IonicContact NZ-OE2 2.69Å; K479-E550 PolarHBondContact NZ-OE2 2.74Å; K479-V551 HydrophobicContact CG-CG2 3.74Å
480D97.7Very high95.6Very high10 Ų1035.5 Ų35.55%0.05317%0.169CC..Hα-helixtrans-58.7-44.2175.4-65.30.4000110.3K461 R463 F477 E483 D484K461-D480 HydrophobicContact CD-CB 4.18Å; K461-D480 HydrophobicContact CG-CB 4.24Å; K461-D480 PolarHBondContact N-OD2 3.41Å; R463-D480 IonicContact CZ-OD1 3.34Å; R463-D480 VanDerWaalsContact CZ-OD1 3.29Å; R463-D480 IonicContact NE-OD1 3.98Å; R463-D480 PolarHBondContact NE-OD1 2.94Å; R463-D480 IonicContact NH2-OD1 3.25Å; R463-D480 PolarHBondContact NH2-OD1 3.46Å; F477-D480 WeakPolarHBondContact O-CB 3.13Å; F477-D480 PolarHBondContact O-N 2.97Å; F477-D480 VanDerWaalsContact O-N 3.14Å; D480-E483 PolarHBondContact O-N 2.97Å; D480-D484 WeakPolarHBondContact O-CB 3.26Å; D480-D484 PolarHBondContact O-N 3.15Å
481I97.6Very high95.6Very high20 Ų2033.1 Ų33.110%0.10316%0.161CC..Hα-helixtrans-61.2-45.8178-65166.6000111.2L236 I238 F242 F477 I478 K479 A485 L490 W495L236-I481 HydrophobicContact CD1-CG2 4.07Å; I238-I481 HydrophobicContact CD1-CD1 4.42Å; I238-I481 HydrophobicContact CD1-CG2 4.35Å; F242-I481 HydrophobicContact CD2-CD1 3.74Å; F242-I481 HydrophobicContact CE2-CD1 3.88Å; F477-I481 WeakPolarHBondContact O-CG1 3.39Å; F477-I481 PolarHBondContact O-N 3.39Å; F477-I481 VanDerWaalsContact O-N 3.13Å; I478-I481 PolarHBondContact O-N 3.05Å; K479-I481 VanDerWaalsContact C-N 3.28Å; K479-I481 PolarHBondContact O-N 2.93Å; I481-A485 VanDerWaalsContact O-CB 3.27Å; I481-A485 WeakPolarHBondContact O-CB 3.42Å; I481-A485 PolarHBondContact O-N 2.92Å; I481-L490 HydrophobicContact CG2-CD2 4.34Å; I481-W495 HydrophobicContact CD1-CH2 3.94Å; I481-W495 HydrophobicContact CD1-CZ2 3.8Å; I481-W495 HydrophobicContact CG1-CH2 4.34Å; I481-W495 HydrophobicContact CG1-CZ2 3.93Å; I481-W495 HydrophobicContact CG2-CH2 3.67Å; I481-W495 HydrophobicContact CG2-CZ2 3.83Å; I481-W495 HydrophobicContact CG2-CZ3 4.3Å
482M97.9Very high95.5Very high0 Ų035.1 Ų35.10%018%0.179CC..Hα-helixtrans-63.9-47.3179.7-70.6163.8178.200111.6I478 K479 A485 I486 L532 I534 C547 A548 V551 V560 I562I478-M482 HydrophobicContact CD1-CE 3.94Å; I478-M482 HydrophobicContact CG1-CE 3.93Å; I478-M482 HydrophobicContact CG2-CE 4Å; I478-M482 HydrophobicContact CG2-SD 4.44Å; I478-M482 WeakPolarHBondContact O-CB 3.34Å; I478-M482 WeakPolarHBondContact O-CG 3.24Å; I478-M482 PolarHBondContact O-N 3.28Å; K479-M482 PolarHBondContact O-N 3.32Å; M482-A485 WeakPolarHBondContact O-CB 3.34Å; M482-A485 PolarHBondContact O-N 2.97Å; M482-I486 VanDerWaalsContact O-CG1 3.31Å; M482-I486 WeakPolarHBondContact O-CG1 3.28Å; M482-I486 PolarHBondContact O-N 2.8Å; M482-L532 HydrophobicContact CB-CD2 4.19Å; M482-L532 HydrophobicContact CG-CD2 4.36Å; M482-I534 HydrophobicContact CE-CG1 4.16Å; M482-I534 HydrophobicContact CG-CD1 4.46Å; M482-I534 HydrophobicContact CG-CG1 4.33Å; M482-C547 HydrophobicContact SD-CB 4.43Å; M482-A548 HydrophobicContact CE-CB 3.89Å; M482-A548 HydrophobicContact SD-CB 4.41Å; M482-V551 HydrophobicContact CB-CB 4.49Å; M482-V551 HydrophobicContact CB-CG1 4.08Å; M482-V551 HydrophobicContact CB-CG2 4.13Å; M482-V551 HydrophobicContact SD-CG2 4.21Å; M482-V560 HydrophobicContact CE-CG1 3.98Å; M482-V560 HydrophobicContact CG-CG1 4.14Å; M482-V560 HydrophobicContact SD-CG1 3.97Å; M482-I562 HydrophobicContact CE-CB 4.44Å; M482-I562 HydrophobicContact CE-CD1 3.87Å
483E96.8Very high95.4Very high29 Ų2942.2 Ų42.214%0.13621%0.205CC..Hα-helixtrans-61.5-46.7177.5-70.4168.7-177.800111.4K461 R463 K479 D480 A485 I486 D487 V551K461-E483 WeakPolarHBondContact CD-OE2 3.47Å; K461-E483 VanDerWaalsContact NZ-CB 3.31Å; K461-E483 IonicContact NZ-OE2 3.68Å; K461-E483 PolarHBondContact NZ-OE2 2.68Å; R463-E483 IonicContact CZ-OE1 2.71Å; R463-E483 IonicContact CZ-OE2 3.72Å; R463-E483 IonicContact NH1-OE1 3.22Å; R463-E483 PolarHBondContact NH1-OE1 3.49Å; R463-E483 IonicContact NH2-OE1 3.3Å; R463-E483 PolarHBondContact NH2-OE1 3.29Å; R463-E483 IonicContact NH2-OE2 3.6Å; R463-E483 PolarHBondContact NH2-OE2 3.35Å; K479-E483 WeakPolarHBondContact O-CG 3.29Å; K479-E483 PolarHBondContact O-N 2.65Å; D480-E483 PolarHBondContact O-N 2.97Å; E483-A485 VanDerWaalsContact C-N 3.26Å; E483-A485 PolarHBondContact O-N 3.36Å; E483-I486 PolarHBondContact O-N 3.22Å; E483-D487 WeakPolarHBondContact O-CB 3.43Å; E483-D487 PolarHBondContact O-N 2.83Å; E483-V551 HydrophobicContact CG-CG2 4.21Å
484D95.6Very high95.3Very high39 Ų3946.2 Ų46.221%0.20922%0.224CC..Hα-helixtrans-67-29.1177.8-73.3-13.7000112.1K461 D480 N488 R489 L490K461-D484 WeakPolarHBondContact CE-OD1 3.28Å; K461-D484 IonicContact NZ-OD1 2.63Å; K461-D484 PolarHBondContact NZ-OD1 3.41Å; D480-D484 WeakPolarHBondContact O-CB 3.26Å; D480-D484 PolarHBondContact O-N 3.15Å; D484-N488 CarbonylContact O-C 3.54Å; D484-N488 PolarHBondContact O-N 3.19Å; D484-N488 VanDerWaalsContact O-N 3.12Å; D484-R489 HydrophobicContact CB-CB 4.1Å; D484-R489 PolarHBondContact O-N 3.06Å; D484-L490 HydrophobicContact CB-CD2 3.72Å; D484-L490 HydrophobicContact CB-CG 4.14Å; D484-L490 PolarHBondContact O-N 2.68Å
485A94.7Very high95.3Very high0 Ų045.7 Ų45.70%022%0.223CC..Hα-helixtrans-66-49.8171.700000110.8L236 I481 M482 E483 D487 N488 L490 W505 L532L236-A485 HydrophobicContact CD1-CB 3.77Å; I481-A485 VanDerWaalsContact O-CB 3.27Å; I481-A485 WeakPolarHBondContact O-CB 3.42Å; I481-A485 PolarHBondContact O-N 2.92Å; M482-A485 WeakPolarHBondContact O-CB 3.34Å; M482-A485 PolarHBondContact O-N 2.97Å; E483-A485 VanDerWaalsContact C-N 3.26Å; E483-A485 PolarHBondContact O-N 3.36Å; A485-D487 VanDerWaalsContact C-N 3.33Å; A485-D487 PolarHBondContact O-N 3.43Å; A485-N488 PolarHBondContact O-N 3.45Å; A485-N488 VanDerWaalsContact O-N 3.07Å; A485-L490 HydrophobicContact CB-CD1 3.66Å; A485-L490 HydrophobicContact CB-CG 4.22Å; A485-W505 PolarHBondContact O-NE1 3.48Å; A485-L532 HydrophobicContact CB-CD1 4.02Å; A485-L532 HydrophobicContact CB-CD2 3.77Å
486I94.1Very high95.2Very high1 Ų146 Ų461%0.00523%0.225CC..Hα-helixtrans-59.3-44.4179.2-68.2169.8000111.1M482 E483 N488 W505 S508 L532 V551 H555 C558 V560M482-I486 VanDerWaalsContact O-CG1 3.31Å; M482-I486 WeakPolarHBondContact O-CG1 3.28Å; M482-I486 PolarHBondContact O-N 2.8Å; E483-I486 PolarHBondContact O-N 3.22Å; I486-N488 PolarHBondContact O-N 3.11Å; I486-W505 PolarHBondContact O-NE1 2.83Å; I486-S508 PolarHBondContact O-N 3.48Å; I486-L532 HydrophobicContact CG1-CD2 4.06Å; I486-V551 HydrophobicContact CD1-CG1 3.39Å; I486-H555 HydrophobicContact CD1-CB 3.99Å; I486-H555 HydrophobicContact CG2-CB 4.29Å; I486-C558 HydrophobicContact CD1-CB 4.18Å; I486-C558 HydrophobicContact CG1-CB 4.17Å; I486-C558 HydrophobicContact CG2-CB 4.33Å; I486-V560 HydrophobicContact CD1-CG2 4.06Å
487D92.1Very high95Very high58 Ų5849 Ų4931%0.3124%0.236SC..THydrogen-bonded Turntrans-79-0179.3-71.7-14000113.7E483 A485 R489 H555E483-D487 WeakPolarHBondContact O-CB 3.43Å; E483-D487 PolarHBondContact O-N 2.83Å; A485-D487 VanDerWaalsContact C-N 3.33Å; A485-D487 PolarHBondContact O-N 3.43Å; D487-R489 VanDerWaalsContact C-N 3.31Å; D487-R489 HydrophobicContact CB-CG 3.99Å; D487-R489 PolarHBondContact O-N 3.18Å; D487-H555 IonicContact OD1-CE1 3.04Å
488N90.3Very high94.7Very high95 Ų9549.5 Ų49.551%0.50824%0.243SC..THydrogen-bonded Turntrans57.239.4-177.6-163.243.3000113.7D484 A485 I486D484-N488 CarbonylContact O-C 3.54Å; D484-N488 PolarHBondContact O-N 3.19Å; D484-N488 VanDerWaalsContact O-N 3.12Å; A485-N488 PolarHBondContact O-N 3.45Å; A485-N488 VanDerWaalsContact O-N 3.07Å; I486-N488 PolarHBondContact O-N 3.11Å
489R93.9Very high93.7Very high177 Ų17750.7 Ų50.767%0.66825%0.252SS*.  trans-104.4-5.9-179.6-67.2179.9178.3175.61.9114.4D484 D487 D491D484-R489 HydrophobicContact CB-CB 4.1Å; D484-R489 PolarHBondContact O-N 3.06Å; D487-R489 VanDerWaalsContact C-N 3.31Å; D487-R489 HydrophobicContact CB-CG 3.99Å; D487-R489 PolarHBondContact O-N 3.18Å; R489-D491 PolarHBondContact O-N 2.9Å
490L93.3Very high92Very high14 Ų1462 Ų627%0.07329%0.294CS..SBendtrans-61.4122175.2-70-178.3000111.9R195 L236 I481 D484 A485 S492 W495R195-L490 PolarHBondContact NH2-O 2.69Å; R195-L490 VanDerWaalsContact NH2-O 3.14Å; L236-L490 HydrophobicContact CD1-CD1 3.8Å; L236-L490 HydrophobicContact CD2-CD1 4.37Å; I481-L490 HydrophobicContact CG2-CD2 4.34Å; D484-L490 HydrophobicContact CB-CD2 3.72Å; D484-L490 HydrophobicContact CB-CG 4.14Å; D484-L490 PolarHBondContact O-N 2.68Å; A485-L490 HydrophobicContact CB-CD1 3.66Å; A485-L490 HydrophobicContact CB-CG 4.22Å; L490-S492 PolarHBondContact O-N 2.61Å; L490-W495 HydrophobicContact CB-CB 4.18Å; L490-W495 HydrophobicContact CB-CG 4.13Å; L490-W495 HydrophobicContact CD1-CB 4.46Å; L490-W495 HydrophobicContact CD1-CD2 4.19Å; L490-W495 HydrophobicContact CD1-CE3 4.45Å; L490-W495 HydrophobicContact CD1-CG 4.19Å; L490-W495 HydrophobicContact CD2-CD2 4.45Å; L490-W495 HydrophobicContact CD2-CG 4.37Å; L490-W495 HydrophobicContact CG-CG 4.48Å
491D93.1Very high90Very high80 Ų8066.8 Ų66.843%0.42833%0.327SS..  trans-54.8130177.8178.5-85000111.8R489 K493 E494 W495R489-D491 PolarHBondContact O-N 2.9Å; D491-K493 VanDerWaalsContact C-N 3.31Å; D491-K493 PolarHBondContact O-N 3.24Å; D491-K493 VanDerWaalsContact OD1-CA 3.31Å; D491-K493 WeakPolarHBondContact OD1-CA 3.5Å; D491-K493 VanDerWaalsContact OD1-CB 3.24Å; D491-K493 WeakPolarHBondContact OD1-CB 3.15Å; D491-K493 PolarHBondContact OD1-N 3.04Å; D491-E494 HydrophobicContact CB-CB 4.26Å; D491-E494 HydrophobicContact CB-CG 4.35Å; D491-E494 PolarHBondContact O-N 2.94Å; D491-E494 PolarHBondContact OD1-N 3.46Å; D491-W495 WeakPolarHBondContact O-CA 3.37Å; D491-W495 WeakPolarHBondContact O-CB 3.15Å; D491-W495 PolarHBondContact O-N 2.96Å
492S91.6Very high88.4Confident83 Ų8367.8 Ų67.858%0.5833%0.334SS*.THydrogen-bonded Turntrans-74.5-16-173.6-58.90000114.4L490 P496L490-S492 PolarHBondContact O-N 2.61Å; S492-P496 WeakPolarHBondContact O-CA 3.19Å
493K93.5Very high86.8Confident178 Ų17869.3 Ų69.377%0.77435%0.347SS*.THydrogen-bonded Turntrans-84.6-37.7174.2-58.5178.2179.4174.80111S198 D491S198-K493 PolarHBondContact OG-O 3.35Å; D491-K493 VanDerWaalsContact C-N 3.31Å; D491-K493 PolarHBondContact O-N 3.24Å; D491-K493 VanDerWaalsContact OD1-CA 3.31Å; D491-K493 WeakPolarHBondContact OD1-CA 3.5Å; D491-K493 VanDerWaalsContact OD1-CB 3.24Å; D491-K493 WeakPolarHBondContact OD1-CB 3.15Å; D491-K493 PolarHBondContact OD1-N 3.04Å
494E94.7Very high85.4Confident93 Ų9372.3 Ų72.344%0.43537%0.367SS..THydrogen-bonded Turntrans-75.9-33.6174.9-67.5-162177.100112.9K197 S198 D491 P496K197-E494 IonicContact NZ-OE2 3.67Å; K197-E494 PolarHBondContact NZ-OE2 2.88Å; S198-E494 PolarHBondContact N-O 3.04Å; S198-E494 PolarHBondContact OG-O 3.36Å; D491-E494 HydrophobicContact CB-CB 4.26Å; D491-E494 HydrophobicContact CB-CG 4.35Å; D491-E494 PolarHBondContact O-N 2.94Å; D491-E494 PolarHBondContact OD1-N 3.46Å; E494-P496 VanDerWaalsContact C-CD 3.4Å; E494-P496 WeakPolarHBondContact O-CD 3.48Å
495W95.8Very high84.5Confident10 Ų1071.5 Ų71.54%0.03836%0.361CS..SBendtrans-126.761.8-175.7-60.191.1000111.6R195 Y196 K197 L236 I238 I481 L490 D491R195-W495 VanDerWaalsContact CZ-O 3.31Å; R195-W495 PolarHBondContact NE-O 2.78Å; R195-W495 PolarHBondContact NH2-O 3.46Å; Y196-W495 WeakPolarHBondContact O-CA 3.49Å; K197-W495 HydrophobicContact CB-CE3 4.17Å; K197-W495 HydrophobicContact CB-CH2 3.88Å; K197-W495 HydrophobicContact CB-CZ2 4.31Å; K197-W495 HydrophobicContact CB-CZ3 3.82Å; K197-W495 HydrophobicContact CD-CD2 4.24Å; K197-W495 HydrophobicContact CD-CH2 4.2Å; K197-W495 HydrophobicContact CD-CZ2 3.74Å; K197-W495 HydrophobicContact CG-CH2 4.38Å; K197-W495 HydrophobicContact CG-CZ2 4.39Å; L236-W495 HydrophobicContact CB-CZ3 4.48Å; I238-W495 HydrophobicContact CD1-CH2 3.65Å; I238-W495 HydrophobicContact CD1-CZ3 3.98Å; I238-W495 HydrophobicContact CG1-CH2 3.74Å; I238-W495 HydrophobicContact CG1-CZ3 3.71Å; I238-W495 HydrophobicContact CG2-CH2 4.34Å; I481-W495 HydrophobicContact CD1-CH2 3.94Å; I481-W495 HydrophobicContact CD1-CZ2 3.8Å; I481-W495 HydrophobicContact CG1-CH2 4.34Å; I481-W495 HydrophobicContact CG1-CZ2 3.93Å; I481-W495 HydrophobicContact CG2-CH2 3.67Å; I481-W495 HydrophobicContact CG2-CZ2 3.83Å; I481-W495 HydrophobicContact CG2-CZ3 4.3Å; L490-W495 HydrophobicContact CB-CB 4.18Å; L490-W495 HydrophobicContact CB-CG 4.13Å; L490-W495 HydrophobicContact CD1-CB 4.46Å; L490-W495 HydrophobicContact CD1-CD2 4.19Å; L490-W495 HydrophobicContact CD1-CE3 4.45Å; L490-W495 HydrophobicContact CD1-CG 4.19Å; L490-W495 HydrophobicContact CD2-CD2 4.45Å; L490-W495 HydrophobicContact CD2-CG 4.37Å; L490-W495 HydrophobicContact CG-CG 4.48Å; D491-W495 WeakPolarHBondContact O-CA 3.37Å; D491-W495 WeakPolarHBondContact O-CB 3.15Å; D491-W495 PolarHBondContact O-N 2.96Å
496P95.5Very high83.3Confident26 Ų2672.7 Ų72.717%0.16937%0.368CS..  trans-63.7152.2179.429-37.8000112R195 Y196 S492 E494R195-P496 VanDerWaalsContact CA-O 3.29Å; R195-P496 WeakPolarHBondContact CA-O 3.32Å; R195-P496 WeakPolarHBondContact CB-O 3.32Å; Y196-P496 HydrophobicContact CD2-CG 4.14Å; Y196-P496 HydrophobicContact CE1-CG 3.96Å; Y196-P496 HydrophobicContact CE2-CG 3.51Å; Y196-P496 VanDerWaalsContact CZ-CG 3.41Å; Y196-P496 PolarHBondContact N-O 2.72Å; Y196-P496 WeakPolarHBondContact O-CD 3.44Å; S492-P496 WeakPolarHBondContact O-CA 3.19Å; E494-P496 VanDerWaalsContact C-CD 3.4Å; E494-P496 WeakPolarHBondContact O-CD 3.48Å
497Y92.9Very high82Confident63 Ų6372.7 Ų72.725%0.24737%0.367CS..BIsolated β-bridgetrans-80.8146165.9-72-89.8000110.4V194 R195 Q234 S499 P502V194-Y497 WeakPolarHBondContact O-CA 3.42Å; R195-Y497 VanDerWaalsContact CD-CZ 3.49Å; R195-Y497 HydrophobicContact CG-CD1 3.37Å; R195-Y497 HydrophobicContact CG-CD2 4.25Å; R195-Y497 HydrophobicContact CG-CE1 3.41Å; R195-Y497 VanDerWaalsContact CG-CE1 3.41Å; R195-Y497 HydrophobicContact CG-CE2 4.29Å; R195-Y497 HydrophobicContact CG-CG 3.82Å; Q234-Y497 PolarHBondContact NE2-OH 3.45Å; Y497-S499 WeakPolarHBondContact CB-O 3.49Å; Y497-P502 HydrophobicContact CD1-CB 3.98Å; Y497-P502 HydrophobicContact CD1-CG 3.93Å; Y497-P502 HydrophobicContact CE1-CB 3.79Å; Y497-P502 HydrophobicContact CE1-CG 3.87Å; Y497-P502 HydrophobicContact CE2-CG 4.48Å; Y497-P502 HydrophobicContact CG-CG 4.27Å
498C91.1Very high80.8Confident41 Ų4172.6 Ų72.628%0.27737%0.371SS..SBendtrans-66.8-40.8169.1-69.60000111.9V194 A208 E212V194-C498 HydrophobicContact CB-CB 4.39Å; V194-C498 PolarHBondContact O-N 2.91Å; A208-C498 VanDerWaalsContact C-SG 3.54Å; A208-C498 VanDerWaalsContact CB-SG 3.53Å; A208-C498 PolarHBondContact O-SG 3.07Å; A208-C498 VanDerWaalsContact O-SG 3.4Å; E212-C498 HydrophobicContact CB-CB 3.89Å; E212-C498 HydrophobicContact CG-CB 3.87Å
499S77.2Confident79.4Confident26 Ų2670.1 Ų70.118%0.18237%0.368CS..SBendtrans-112.3153.3-17853.30000113E212 Y497 C501E212-S499 WeakPolarHBondContact OE1-CB 3.43Å; E212-S499 PolarHBondContact OE1-OG 3.32Å; Y497-S499 WeakPolarHBondContact CB-O 3.49Å; S499-C501 VanDerWaalsContact C-N 3.31Å; S499-C501 PolarHBondContact O-N 3.04Å
500R61.7Low77.6Confident260 Ų26065.1 Ų65.198%0.98137%0.365SS*.SBendtrans-77.1-12-176.6-68.9-173179.6-171.40.7114.2P502R500-P502 VanDerWaalsContact C-CD 3.48Å
501C56Low75.6Confident109 Ų10968.7 Ų68.774%0.73639%0.387SS*.  trans-130.958.7-170.3-145.80000112.5S499S499-C501 VanDerWaalsContact C-N 3.31Å; S499-C501 PolarHBondContact O-N 3.04Å
502P64.7Low73.5Confident41 Ų4168.3 Ų68.327%0.26639%0.391SS..  trans-61.6148.9167.528.7-33.2000109.4Y497 R500Y497-P502 HydrophobicContact CD1-CB 3.98Å; Y497-P502 HydrophobicContact CD1-CG 3.93Å; Y497-P502 HydrophobicContact CE1-CB 3.79Å; Y497-P502 HydrophobicContact CE1-CG 3.87Å; Y497-P502 HydrophobicContact CE2-CG 4.48Å; Y497-P502 HydrophobicContact CG-CG 4.27Å; R500-P502 VanDerWaalsContact C-CD 3.48Å
503A65.1Low71.4Confident32 Ų3269.6 Ų69.626%0.26441%0.407SS..  trans-56.3154.4164.900000109.4K230 T231 W505K230-A503 HydrophobicContact CB-CB 4.2Å; K230-A503 WeakPolarHBondContact O-CB 3.47Å; T231-A503 WeakPolarHBondContact O-CB 3.2Å; A503-W505 PolarHBondContact O-N 2.81Å
504V67.6Low69.2Low92 Ų9272.3 Ų72.356%0.55841%0.412SS*.  trans-60.4106.9176.5-178.40000108.3
505W76.4Confident66.8Low22 Ų2272.9 Ų72.98%0.08342%0.415CS..  trans-71.2129.8175.5170.9-108.9000110Q232 Q234 A485 I486 A503 L532Q232-W505 WeakPolarHBondContact O-CZ3 3.22Å; Q234-W505 HydrophobicContact CB-CE3 4.19Å; Q234-W505 HydrophobicContact CB-CH2 4.2Å; Q234-W505 HydrophobicContact CB-CZ3 3.94Å; Q234-W505 HydrophobicContact CG-CD2 3.84Å; Q234-W505 HydrophobicContact CG-CE3 3.57Å; Q234-W505 HydrophobicContact CG-CG 4.37Å; Q234-W505 HydrophobicContact CG-CH2 4.37Å; Q234-W505 HydrophobicContact CG-CZ3 3.86Å; Q234-W505 VanDerWaalsContact NE2-CB 3.27Å; A485-W505 PolarHBondContact O-NE1 3.48Å; I486-W505 PolarHBondContact O-NE1 2.83Å; A503-W505 PolarHBondContact O-N 2.81Å; W505-L532 HydrophobicContact CH2-CB 4.15Å; W505-L532 HydrophobicContact CH2-CD1 4.41Å
506N69.8Low64.1Low26 Ų2681.6 Ų81.614%0.13945%0.453CS..  trans-141.262.8176.1-171.415.2000110.3S508 G509 A510N506-S508 PolarHBondContact O-N 3.06Å; N506-S508 VanDerWaalsContact O-N 3.16Å; N506-S508 PolarHBondContact OD1-OG 3.44Å; N506-G509 PolarHBondContact O-N 3.15Å; N506-G509 PolarHBondContact OD1-N 2.81Å; N506-A510 PolarHBondContact ND2-N 3.03Å; N506-A510 PolarHBondContact ND2-O 2.99Å; N506-A510 PolarHBondContact OD1-N 2.95Å; N506-A510 PolarHBondContact OD1-O 2.67Å
507G65.5Low61.5Low0 Ų085.8 Ų85.80%048%0.48CS..THydrogen-bonded Turntrans-56.2-30.8179.500000113.4G509 S557G507-G509 VanDerWaalsContact C-N 3.33Å; G507-G509 PolarHBondContact O-N 2.74Å; G507-S557 PolarHBondContact O-OG 3.15Å
508S66.9Low59.1Low56 Ų5693.9 Ų93.939%0.39251%0.51SS..THydrogen-bonded Turntrans-76.4-14.5176.564.90000114.5I486 N506 A510I486-S508 PolarHBondContact O-N 3.48Å; N506-S508 PolarHBondContact O-N 3.06Å; N506-S508 VanDerWaalsContact O-N 3.16Å; N506-S508 PolarHBondContact OD1-OG 3.44Å; S508-A510 PolarHBondContact O-N 3.3Å
509G61.8Low56.7Low43 Ų4396.2 Ų96.244%0.44352%0.523SS..  trans73.24.7-174.700000115.1N506 G507 V511N506-G509 PolarHBondContact O-N 3.15Å; N506-G509 PolarHBondContact OD1-N 2.81Å; G507-G509 VanDerWaalsContact C-N 3.33Å; G507-G509 PolarHBondContact O-N 2.74Å; G509-V511 PolarHBondContact O-N 3.19Å
510A55.5Low55Low72 Ų72101.6 Ų101.660%0.59555%0.55SS*.  trans-75.4109.8179.600000111.5N506 S508N506-A510 PolarHBondContact ND2-N 3.03Å; N506-A510 PolarHBondContact ND2-O 2.99Å; N506-A510 PolarHBondContact OD1-N 2.95Å; N506-A510 PolarHBondContact OD1-O 2.67Å; S508-A510 PolarHBondContact O-N 3.3Å
511V52.4Low54.2Low89 Ų8996.8 Ų96.854%0.53953%0.533SS..  trans-89.5132.3-179.4-71.90000111.9G509G509-V511 PolarHBondContact O-N 3.19Å
512S48.9Very low53.6Low72 Ų7294 Ų9450%0.50351%0.511SS..  trans-71133165.3176.10000109.8R514 Q515S512-R514 PolarHBondContact O-N 3.38Å; S512-Q515 PolarHBondContact O-N 2.83Å; S512-Q515 VanDerWaalsContact O-N 3.11Å
513A45.9Very low52.5Low111 Ų11199 Ų9992%0.91753%0.53SS*.THydrogen-bonded Turntrans-57.2-10.9178.100000114.5
514R47.1Very low51.5Low235 Ų235103.9 Ų103.989%0.88755%0.551SS**THydrogen-bonded Turntrans-88.3-8.9179.2-68.8-175.8179.5-1770.4114.7S512 K516S512-R514 PolarHBondContact O-N 3.38Å; R514-K516 PolarHBondContact O-N 2.89Å
515Q45.6Very low50.5Low105 Ų105102.1 Ų102.149%0.49154%0.538SS..  trans-86.799.3178.4-73.3-179.9-23.900110.9S512S512-Q515 PolarHBondContact O-N 2.83Å; S512-Q515 VanDerWaalsContact O-N 3.11Å
516K38.4Very low49.1Very low193 Ų193109.8 Ų109.884%0.83957%0.567SS**  trans-69.7133.2165.3-76.8-174.1176.7-178.50109.1R514 R518R514-K516 PolarHBondContact O-N 2.89Å; K516-R518 PolarHBondContact O-N 3.46Å
517P40.9Very low48.1Very low113 Ų113117.2 Ų117.273%0.73460%0.599SS**  trans-71.3106.9-17826.2-26.8000108.7
518R42.5Very low47.7Very low233 Ų233122.9 Ų122.988%0.87963%0.629SS**  trans-111.666.5178.1-127.1-172.5177.5157.5-1.6108.2K516K516-R518 PolarHBondContact O-N 3.46Å
519T40.2Very low47.8Very low90 Ų90121.4 Ų121.455%0.55262%0.623SS**  trans157140.2155.936.90000111.7Y521 L522T519-Y521 PolarHBondContact O-N 2.92Å; T519-Y521 VanDerWaalsContact O-N 3.16Å; T519-L522 PolarHBondContact O-N 3.21Å
520N43.1Very low49Very low140 Ų140120 Ų12075%0.74961%0.606SS**THydrogen-bonded Turntrans-60.5-19178.7-71.9-4.2000114.3L522 E523N520-L522 VanDerWaalsContact C-N 3.25Å; N520-L522 PolarHBondContact O-N 3.41Å; N520-E523 PolarHBondContact O-N 3.12Å
521Y44.2Very low50.8Low158 Ų158118.2 Ų118.262%0.6258%0.584SS**Hα-helixtrans-61.8-31.9176.2-76.7-86.4000112.6T519 E523 L524 D525T519-Y521 PolarHBondContact O-N 2.92Å; T519-Y521 VanDerWaalsContact O-N 3.16Å; Y521-E523 VanDerWaalsContact C-N 3.28Å; Y521-E523 PolarHBondContact O-N 3.37Å; Y521-L524 PolarHBondContact O-N 3.11Å; Y521-D525 PolarHBondContact O-N 2.99Å
522L43.6Very low52.9Low52 Ų52114 Ų11427%0.27256%0.558SS.*Hα-helixtrans-65.9-25.7179.1-68.4169.1000113.5Q232 T519 N520 R526Q232-L522 VanDerWaalsContact NE2-CD2 3.25Å; T519-L522 PolarHBondContact O-N 3.21Å; N520-L522 VanDerWaalsContact C-N 3.25Å; N520-L522 PolarHBondContact O-N 3.41Å; L522-R526 WeakPolarHBondContact O-CD 3.36Å; L522-R526 WeakPolarHBondContact O-CG 3.49Å; L522-R526 PolarHBondContact O-N 2.98Å
523E40.7Very low55.3Low146 Ų146110.6 Ų110.668%0.68253%0.534SS*.Hα-helixtrans-78.3-30.7179-70.9-169.5159.700112.6N520 Y521N520-E523 PolarHBondContact O-N 3.12Å; Y521-E523 VanDerWaalsContact C-N 3.28Å; Y521-E523 PolarHBondContact O-N 3.37Å
524L44.5Very low57.8Low133 Ų133105.3 Ų105.370%0.69649%0.49SS*.Hα-helixtrans-73.1-44176-130.982.2000110.9Y521 R526 K527Y521-L524 PolarHBondContact O-N 3.11Å; L524-R526 VanDerWaalsContact C-N 3.27Å; L524-R526 PolarHBondContact O-N 2.61Å; L524-K527 PolarHBondContact O-N 2.91Å
525D45.9Very low60.3Low55 Ų5594.1 Ų94.129%0.29445%0.448SS..Hα-helixtrans-61-35.6176.1-75.5-13.9000111.9Y521 K527 N528 G529Y521-D525 PolarHBondContact O-N 2.99Å; D525-K527 PolarHBondContact O-N 3.35Å; D525-N528 PolarHBondContact O-N 2.79Å; D525-G529 PolarHBondContact O-N 2.73Å; D525-G529 VanDerWaalsContact O-N 3.09Å
526R47.6Very low62.8Low183 Ų18389.1 Ų89.169%0.69143%0.425SS*.Hα-helixtrans-63.6-24.3178.1-79.9174.290.1121.67.9114.3L522 L524L522-R526 WeakPolarHBondContact O-CD 3.36Å; L522-R526 WeakPolarHBondContact O-CG 3.49Å; L522-R526 PolarHBondContact O-N 2.98Å; L524-R526 VanDerWaalsContact C-N 3.27Å; L524-R526 PolarHBondContact O-N 2.61Å
527K48.6Very low65.7Low183 Ų18379.9 Ų79.980%0.79639%0.385SS*.Hα-helixtrans-78.4-26.2177.6-79.1-175.2179.11750112.8L524 D525L524-K527 PolarHBondContact O-N 2.91Å; D525-K527 PolarHBondContact O-N 3.35Å
528N56.9Low68.4Low119 Ų11974.5 Ų74.564%0.63635%0.35SS*.Hα-helixtrans-103.6-13.1-175.1-70.9-9.4000113.9D525D525-N528 PolarHBondContact O-N 2.79Å
529G70.5Confident71Confident25 Ų2563.4 Ų63.426%0.25831%0.308SS..  trans79.4165.1-175.700000112.2D525 S557D525-G529 PolarHBondContact O-N 2.73Å; D525-G529 VanDerWaalsContact O-N 3.09Å; G529-S557 CarbonylContact C-O 3.5Å; G529-S557 WeakPolarHBondContact CA-O 3.46Å
530S87Confident73.8Confident13 Ų1359.1 Ų59.19%0.09128%0.282CS..EExtended strand (participates in β ladder)trans-74.8154.6174.9-60.40000110.5S557 C558 E559S530-S557 PolarHBondContact N-O 3.2Å; S530-C558 CarbonylContact O-C 3.56Å; S530-C558 WeakPolarHBondContact O-CA 3.19Å; S530-C558 PolarHBondContact O-SG 3.39Å; S530-E559 PolarHBondContact O-N 2.89Å
531R93Very high76.4Confident35 Ų3552.9 Ų52.913%0.13225%0.249CC..EExtended strand (participates in β ladder)trans-115.4133.2174.6-65.2-168.1-178.4116.9-12.7112.3L188 E190 S233 Q234 E559L188-R531 PolarHBondContact O-NH1 3.33Å; E190-R531 IonicContact OE1-CZ 3.51Å; E190-R531 IonicContact OE1-NE 3.05Å; E190-R531 IonicContact OE1-NH1 2.68Å; E190-R531 PolarHBondContact OE1-NH1 3.18Å; S233-R531 CarbonylContact C-O 3.59Å; S233-R531 WeakPolarHBondContact CA-O 3.36Å; S233-R531 WeakPolarHBondContact CB-O 3.35Å; Q234-R531 PolarHBondContact N-O 3.48Å; R531-E559 WeakPolarHBondContact CA-O 3.4Å; R531-E559 HydrophobicContact CG-CB 4.43Å; R531-E559 IonicContact NE-OE2 3.12Å; R531-E559 PolarHBondContact NE-OE2 2.86Å; R531-E559 VanDerWaalsContact NE-OE2 3.13Å
532L96.6Very high79Confident0 Ų046.4 Ų46.40%022%0.223CC..EExtended strand (participates in β ladder)trans-107.1108.2168.4179.663000108.6Q234 L236 M482 A485 I486 W505 I534 E559 V560 I561Q234-L532 HydrophobicContact CB-CD1 3.92Å; L236-L532 HydrophobicContact CD1-CD1 4.08Å; L236-L532 HydrophobicContact CG-CD1 3.94Å; M482-L532 HydrophobicContact CB-CD2 4.19Å; M482-L532 HydrophobicContact CG-CD2 4.36Å; A485-L532 HydrophobicContact CB-CD1 4.02Å; A485-L532 HydrophobicContact CB-CD2 3.77Å; I486-L532 HydrophobicContact CG1-CD2 4.06Å; W505-L532 HydrophobicContact CH2-CB 4.15Å; W505-L532 HydrophobicContact CH2-CD1 4.41Å; L532-I534 HydrophobicContact CD1-CD1 3.98Å; L532-I534 HydrophobicContact CD2-CD1 4.01Å; L532-I534 HydrophobicContact CG-CD1 3.74Å; L532-I534 HydrophobicContact CG-CG1 4.29Å; L532-E559 PolarHBondContact N-O 2.78Å; L532-V560 HydrophobicContact CB-CG2 4.33Å; L532-V560 HydrophobicContact CD2-CG1 4.45Å; L532-V560 HydrophobicContact CD2-CG2 4.29Å; L532-V560 CarbonylContact O-C 3.59Å; L532-V560 VanDerWaalsContact O-CA 3.32Å; L532-V560 WeakPolarHBondContact O-CA 2.98Å; L532-I561 PolarHBondContact O-N 2.85Å
533I98.1Very high81.6Confident0 Ų044.2 Ų44.20%021%0.212CC..EExtended strand (participates in β ladder)trans-95.1128.7177.2-51.9170.4000107.7Y148 L188 E190 Q234 L235 L236 I561Y148-I533 HydrophobicContact CE1-CG2 4.17Å; L188-I533 HydrophobicContact CD1-CD1 3.71Å; L188-I533 HydrophobicContact CD1-CG1 4.1Å; E190-I533 HydrophobicContact CB-CD1 4.38Å; Q234-I533 PolarHBondContact O-N 3.41Å; L235-I533 CarbonylContact C-O 3.59Å; L235-I533 VanDerWaalsContact CA-O 3.26Å; L235-I533 WeakPolarHBondContact CA-O 3.47Å; L235-I533 HydrophobicContact CD1-CB 3.96Å; L235-I533 HydrophobicContact CD1-CG2 3.67Å; L236-I533 PolarHBondContact N-O 3.2Å; I533-I561 CarbonylContact C-O 3.55Å; I533-I561 WeakPolarHBondContact CA-O 3.45Å
534I98.7Very high84.4Confident0 Ų037.2 Ų37.20%018%0.18CC..EExtended strand (participates in β ladder)trans-117.9131.6179.2-53.4-63000108.9Y148 L236 I238 I478 M482 L532 V536 V560 I561 I562 G563Y148-I534 PolarHBondContact OH-O 3.04Å; L236-I534 HydrophobicContact CB-CD1 3.72Å; L236-I534 HydrophobicContact CD1-CD1 3.62Å; L236-I534 HydrophobicContact CG-CD1 3.77Å; I238-I534 HydrophobicContact CD1-CG2 4.26Å; I478-I534 HydrophobicContact CD1-CG2 4.02Å; M482-I534 HydrophobicContact CE-CG1 4.16Å; M482-I534 HydrophobicContact CG-CD1 4.46Å; M482-I534 HydrophobicContact CG-CG1 4.33Å; L532-I534 HydrophobicContact CD1-CD1 3.98Å; L532-I534 HydrophobicContact CD2-CD1 4.01Å; L532-I534 HydrophobicContact CG-CD1 3.74Å; L532-I534 HydrophobicContact CG-CG1 4.29Å; I534-V536 HydrophobicContact CG2-CG2 4.38Å; I534-V560 HydrophobicContact CG1-CG1 4.15Å; I534-I561 PolarHBondContact N-O 3.26Å; I534-I562 HydrophobicContact CB-CB 4.36Å; I534-I562 HydrophobicContact CB-CG1 4.14Å; I534-I562 HydrophobicContact CG2-CG1 4.23Å; I534-I562 CarbonylContact O-C 3.59Å; I534-G563 PolarHBondContact O-N 3.49Å
535F98.9Very high87Confident0 Ų030.9 Ų30.90%015%0.147CC..EExtended strand (participates in β ladder)trans-125.4116.9172-170.5-102.6000111.3Y148 L150 M177 I181 L207 L235 L236 I237 I238 I537 G563 S564 T565Y148-F535 AromaticContact CE2-CD2 3.94Å; Y148-F535 HydrophobicContact CE2-CD2 3.94Å; Y148-F535 HydrophobicContact CE2-CE2 4.35Å; L150-F535 HydrophobicContact CD1-CE1 4.38Å; L150-F535 HydrophobicContact CD1-CE2 3.45Å; L150-F535 VanDerWaalsContact CD1-CE2 3.45Å; L150-F535 HydrophobicContact CD1-CZ 3.35Å; L150-F535 HydrophobicContact CD2-CE2 4.37Å; L150-F535 HydrophobicContact CG-CE2 3.63Å; L150-F535 HydrophobicContact CG-CZ 3.99Å; M177-F535 HydrophobicContact SD-CE1 4.34Å; M177-F535 HydrophobicContact SD-CZ 4.28Å; I181-F535 HydrophobicContact CD1-CD1 3.62Å; I181-F535 HydrophobicContact CD1-CD2 4.16Å; I181-F535 HydrophobicContact CD1-CE1 3.8Å; I181-F535 HydrophobicContact CD1-CE2 4.32Å; I181-F535 HydrophobicContact CD1-CG 3.81Å; I181-F535 HydrophobicContact CD1-CZ 4.14Å; I181-F535 HydrophobicContact CG1-CD2 4.23Å; I181-F535 HydrophobicContact CG1-CE2 4.37Å; I181-F535 HydrophobicContact CG1-CG 4.31Å; L207-F535 HydrophobicContact CD2-CD1 3.78Å; L207-F535 HydrophobicContact CD2-CE1 3.6Å; L235-F535 HydrophobicContact CD1-CB 4.27Å; L236-F535 PolarHBondContact O-N 3.25Å; I237-F535 WeakPolarHBondContact CA-O 3.33Å; I237-F535 HydrophobicContact CG1-CB 4.44Å; I237-F535 HydrophobicContact CG2-CD1 4.35Å; I238-F535 PolarHBondContact N-O 2.79Å; F535-I537 HydrophobicContact CD1-CG1 4.25Å; F535-I537 HydrophobicContact CE1-CG1 4.03Å; F535-G563 WeakPolarHBondContact CA-O 3.2Å; F535-S564 VanDerWaalsContact CE2-C 3.43Å; F535-S564 VanDerWaalsContact CE2-CA 3.42Å; F535-T565 HydrophobicContact CZ-CG2 4.02Å
536V98.8Very high89.5Confident0 Ų029.9 Ų29.90%014%0.139CC..EExtended strand (participates in β ladder)trans-98.7125.5172.7-173.80000109.2I238 F242 I478 I534 G539 I540 G563 S564I238-V536 CarbonylContact O-C 3.56Å; I238-V536 WeakPolarHBondContact O-CA 3.32Å; F242-V536 HydrophobicContact CE1-CG1 4.02Å; F242-V536 HydrophobicContact CE1-CG2 4.24Å; I478-V536 HydrophobicContact CD1-CG2 4Å; I534-V536 HydrophobicContact CG2-CG2 4.38Å; V536-G539 WeakPolarHBondContact CG1-O 3.41Å; V536-I540 HydrophobicContact CB-CG2 3.68Å; V536-I540 HydrophobicContact CG1-CG2 4.48Å; V536-I540 HydrophobicContact CG2-CG2 3.63Å; V536-G563 PolarHBondContact N-O 3.2Å; V536-S564 WeakPolarHBondContact O-CA 3.25Å; V536-S564 WeakPolarHBondContact O-CB 3.38Å; V536-S564 PolarHBondContact O-OG 3.2Å
537I98.7Very high91.9Very high0 Ų021.2 Ų21.20%011%0.106CC..EExtended strand (participates in β ladder)trans-75.4127.3173.8-57.1173.4000107.8C159 Y160 N203 A204 L207 I237 I238 R240 F535C159-I537 HydrophobicContact CB-CG2 4.12Å; Y160-I537 HydrophobicContact CE2-CG2 4.45Å; Y160-I537 PolarHBondContact OH-O 2.8Å; Y160-I537 VanDerWaalsContact OH-O 3.11Å; N203-I537 HydrophobicContact CB-CD1 3.9Å; A204-I537 HydrophobicContact CB-CD1 4.4Å; L207-I537 HydrophobicContact CB-CD1 4.14Å; L207-I537 HydrophobicContact CD2-CD1 3.73Å; L207-I537 HydrophobicContact CD2-CG1 3.72Å; I237-I537 HydrophobicContact CG2-CD1 4Å; I237-I537 HydrophobicContact CG2-CG1 4.17Å; I238-I537 PolarHBondContact O-N 3.09Å; R240-I537 VanDerWaalsContact CB-O 3.28Å; R240-I537 WeakPolarHBondContact CB-O 3.14Å; R240-I537 PolarHBondContact N-O 2.6Å; R240-I537 VanDerWaalsContact N-O 3.12Å; F535-I537 HydrophobicContact CD1-CG1 4.25Å; F535-I537 HydrophobicContact CE1-CG1 4.03Å
538G97.8Very high94.3Very high0 Ų012.5 Ų12.50%07%0.068CC..THydrogen-bonded Turntrans90.417.7173.500000116.4F156 T565F156-G538 WeakPolarHBondContact CD2-O 3.44Å; G538-T565 WeakPolarHBondContact CA-OG1 3.48Å; G538-T565 PolarHBondContact N-OG1 3.44Å
539G98.3Very high96.2Very high0 Ų07.5 Ų7.50%04%0.04CC..  trans110.4152.6169.900000114.2R240 V536 S564 T565 H566R240-G539 WeakPolarHBondContact CD-O 3.49Å; R240-G539 PolarHBondContact NH1-O 3.32Å; V536-G539 WeakPolarHBondContact CG1-O 3.41Å; G539-S564 WeakPolarHBondContact CA-OG 3.4Å; G539-S564 PolarHBondContact N-OG 3.45Å; G539-T565 PolarHBondContact N-OG1 2.81Å; G539-H566 VanDerWaalsContact CA-O 3.25Å; G539-H566 WeakPolarHBondContact CA-O 3.45Å
540I98.6Very high97.5Very high0 Ų08.8 Ų8.80%04%0.039CC..EExtended strand (participates in β ladder)trans-122151.9172.651.6177.6000110.6V147 V536 E544 M545 I562 S564 H566 I567 L568V147-I540 HydrophobicContact CG1-CD1 3.87Å; V536-I540 HydrophobicContact CB-CG2 3.68Å; V536-I540 HydrophobicContact CG1-CG2 4.48Å; V536-I540 HydrophobicContact CG2-CG2 3.63Å; I540-E544 WeakPolarHBondContact CA-OE2 3.36Å; I540-M545 HydrophobicContact CD1-CG 3.83Å; I540-M545 HydrophobicContact CD1-SD 4.43Å; I540-M545 HydrophobicContact CG1-CG 4.41Å; I540-I562 HydrophobicContact CD1-CG1 4.25Å; I540-I562 HydrophobicContact CG2-CD1 4.07Å; I540-I562 HydrophobicContact CG2-CG1 4.29Å; I540-S564 PolarHBondContact N-OG 2.96Å; I540-H566 PolarHBondContact N-O 2.97Å; I540-H566 VanDerWaalsContact N-O 3.17Å; I540-I567 HydrophobicContact CG1-CG1 4.27Å; I540-I567 CarbonylContact O-C 3.56Å; I540-I567 WeakPolarHBondContact O-CA 3.42Å; I540-L568 PolarHBondContact O-N 3.23Å
541T98.5Very high98Very high9 Ų98.2 Ų8.26%0.0554%0.036CC..EExtended strand (participates in β ladder)trans-92.7161.9175.564.90000111.1T247 S543 E544 M545T247-T541 HydrophobicContact CG2-CG2 3.78Å; T541-S543 PolarHBondContact O-N 2.9Å; T541-S543 PolarHBondContact OG1-N 2.86Å; T541-S543 PolarHBondContact OG1-OG 2.81Å; T541-E544 PolarHBondContact N-OE2 2.75Å; T541-E544 PolarHBondContact O-N 3.34Å; T541-E544 WeakPolarHBondContact OG1-CG 3.27Å; T541-E544 PolarHBondContact OG1-N 3.35Å; T541-E544 VanDerWaalsContact OG1-N 3.14Å; T541-E544 PolarHBondContact OG1-OE2 2.83Å; T541-M545 WeakPolarHBondContact O-CG 3.28Å; T541-M545 PolarHBondContact O-N 2.82Å
542Y98.5Very high98.1Very high21 Ų217.4 Ų7.48%0.0824%0.035CC..Hα-helixtrans-60.9-28.9169.2-66.9-73.3000112.9Q255 Y259 M545 R546 I567 T569Q255-Y542 HydrophobicContact CG-CD1 3.56Å; Q255-Y542 HydrophobicContact CG-CE1 4.07Å; Q255-Y542 HydrophobicContact CG-CG 4.14Å; Y259-Y542 HydrophobicContact CD1-CE1 4.5Å; Y259-Y542 AromaticContact CD1-CE2 3.77Å; Y259-Y542 HydrophobicContact CD1-CE2 3.77Å; Y259-Y542 AromaticContact CD1-CZ 3.53Å; Y259-Y542 WeakPolarHBondContact CD1-OH 3.33Å; Y259-Y542 HydrophobicContact CD2-CE1 4.07Å; Y259-Y542 HydrophobicContact CD2-CE2 4.04Å; Y259-Y542 AromaticContact CD2-CZ 3.77Å; Y259-Y542 AromaticContact CE1-CZ 3.83Å; Y259-Y542 WeakPolarHBondContact CE1-OH 3.39Å; Y259-Y542 HydrophobicContact CE2-CE1 4.16Å; Y259-Y542 HydrophobicContact CG-CD2 4.2Å; Y259-Y542 HydrophobicContact CG-CE1 4.23Å; Y259-Y542 AromaticContact CG-CE2 3.45Å; Y259-Y542 HydrophobicContact CG-CE2 3.45Å; Y259-Y542 VanDerWaalsContact CG-CE2 3.45Å; Y259-Y542 AromaticContact CG-CZ 3.46Å; Y259-Y542 VanDerWaalsContact CG-CZ 3.46Å; Y542-M545 HydrophobicContact CD1-CE 3.87Å; Y542-M545 HydrophobicContact CD1-SD 3.74Å; Y542-M545 HydrophobicContact CE1-CE 4.09Å; Y542-M545 HydrophobicContact CE1-SD 4.13Å; Y542-M545 HydrophobicContact CG-SD 4.45Å; Y542-M545 PolarHBondContact O-N 3.12Å; Y542-R546 PolarHBondContact O-N 2.77Å; Y542-I567 HydrophobicContact CD1-CG2 4.4Å; Y542-I567 HydrophobicContact CD2-CG2 4.3Å; Y542-I567 HydrophobicContact CE1-CG2 3.9Å; Y542-I567 HydrophobicContact CE2-CG2 3.77Å; Y542-T569 HydrophobicContact CE2-CG2 4.2Å
543S98.2Very high98Very high6 Ų614.1 Ų14.14%0.0427%0.067CC..Hα-helixtrans-62.4-43175.375.90000111.9E251 T541 R546 C547E251-S543 WeakPolarHBondContact OE2-CA 3.28Å; E251-S543 WeakPolarHBondContact OE2-CB 3.37Å; E251-S543 PolarHBondContact OE2-N 2.87Å; T541-S543 PolarHBondContact O-N 2.9Å; T541-S543 PolarHBondContact OG1-N 2.86Å; T541-S543 PolarHBondContact OG1-OG 2.81Å; S543-R546 WeakPolarHBondContact O-CB 3.49Å; S543-C547 PolarHBondContact O-N 3.21Å; S543-C547 PolarHBondContact O-SG 3.21Å
544E98.7Very high97.8Very high0 Ų017.8 Ų17.80%010%0.097CC..Hα-helixtrans-75.4-36.6179.4-67.8170147.300112.4R240 F242 P476 I478 I540 T541 R546 C547 A548 I562R240-E544 IonicContact CZ-OE1 2.74Å; R240-E544 VanDerWaalsContact CZ-OE1 3.3Å; R240-E544 IonicContact CZ-OE2 2.7Å; R240-E544 VanDerWaalsContact NH1-CD 3.3Å; R240-E544 IonicContact NH1-OE1 2.65Å; R240-E544 PolarHBondContact NH1-OE1 3.21Å; R240-E544 VanDerWaalsContact NH1-OE1 3.12Å; R240-E544 IonicContact NH1-OE2 2.9Å; R240-E544 PolarHBondContact NH1-OE2 2.85Å; R240-E544 IonicContact NH2-OE1 3.17Å; R240-E544 PolarHBondContact NH2-OE1 2.77Å; R240-E544 IonicContact NH2-OE2 2.92Å; F242-E544 VanDerWaalsContact CZ-OE1 3.25Å; F242-E544 WeakPolarHBondContact CZ-OE1 3.42Å; P476-E544 HydrophobicContact CB-CG 4.24Å; I478-E544 HydrophobicContact CB-CG 4.42Å; I478-E544 HydrophobicContact CD1-CB 4.44Å; I478-E544 HydrophobicContact CG2-CB 3.93Å; I478-E544 HydrophobicContact CG2-CG 3.83Å; I540-E544 WeakPolarHBondContact CA-OE2 3.36Å; T541-E544 PolarHBondContact N-OE2 2.75Å; T541-E544 PolarHBondContact O-N 3.34Å; T541-E544 WeakPolarHBondContact OG1-CG 3.27Å; T541-E544 PolarHBondContact OG1-N 3.35Å; T541-E544 VanDerWaalsContact OG1-N 3.14Å; T541-E544 PolarHBondContact OG1-OE2 2.83Å; E544-R546 VanDerWaalsContact C-N 3.32Å; E544-R546 PolarHBondContact O-N 2.78Å; E544-C547 WeakPolarHBondContact O-CB 3.33Å; E544-C547 PolarHBondContact O-N 3.07Å; E544-A548 PolarHBondContact O-N 2.95Å; E544-I562 HydrophobicContact CB-CD1 4.14Å
545M98.6Very high97.4Very high0 Ų019.8 Ų19.80%011%0.106CC..Hα-helixtrans-55.5-50.2171.4-71166.554.700110.2E144 V147 I540 T541 Y542 C547 A548 Y549 I567E144-M545 VanDerWaalsContact CD-CE 3.48Å; E144-M545 HydrophobicContact CG-CE 4.22Å; E144-M545 WeakPolarHBondContact OE1-CE 3.36Å; V147-M545 HydrophobicContact CB-CE 4.3Å; V147-M545 HydrophobicContact CG1-CE 3.97Å; V147-M545 HydrophobicContact CG1-CG 3.9Å; V147-M545 HydrophobicContact CG1-SD 4.11Å; V147-M545 HydrophobicContact CG2-CB 4.03Å; V147-M545 HydrophobicContact CG2-CE 3.96Å; V147-M545 HydrophobicContact CG2-CG 3.9Å; I540-M545 HydrophobicContact CD1-CG 3.83Å; I540-M545 HydrophobicContact CD1-SD 4.43Å; I540-M545 HydrophobicContact CG1-CG 4.41Å; T541-M545 WeakPolarHBondContact O-CG 3.28Å; T541-M545 PolarHBondContact O-N 2.82Å; Y542-M545 HydrophobicContact CD1-CE 3.87Å; Y542-M545 HydrophobicContact CD1-SD 3.74Å; Y542-M545 HydrophobicContact CE1-CE 4.09Å; Y542-M545 HydrophobicContact CE1-SD 4.13Å; Y542-M545 HydrophobicContact CG-SD 4.45Å; Y542-M545 PolarHBondContact O-N 3.12Å; M545-C547 VanDerWaalsContact C-N 3.32Å; M545-C547 PolarHBondContact O-N 2.85Å; M545-A548 WeakPolarHBondContact O-CB 3.44Å; M545-A548 PolarHBondContact O-N 3.43Å; M545-A548 VanDerWaalsContact O-N 3.15Å; M545-Y549 VanDerWaalsContact O-CD2 3.25Å; M545-Y549 WeakPolarHBondContact O-CD2 3.17Å; M545-I567 HydrophobicContact CE-CD1 4.2Å; M545-I567 HydrophobicContact SD-CD1 3.89Å; M545-I567 HydrophobicContact SD-CG1 4.14Å; M545-I567 HydrophobicContact SD-CG2 4.07Å
546R98.2Very high96.8Very high34 Ų3429 Ų2913%0.12815%0.146CC..Hα-helixtrans-54.3-45.5175.2171.4-179.465.7119-9.3112.3E251 H294 Y542 S543 E544 A548 Y549 E550E251-R546 IonicContact OE1-CZ 3.85Å; E251-R546 IonicContact OE1-NE 3.9Å; E251-R546 PolarHBondContact OE1-NE 3.03Å; E251-R546 IonicContact OE1-NH2 2.86Å; E251-R546 PolarHBondContact OE1-NH2 2.81Å; H294-R546 HydrophobicContact CB-CG 3.96Å; H294-R546 WeakPolarHBondContact O-CD 3.48Å; Y542-R546 PolarHBondContact O-N 2.77Å; S543-R546 WeakPolarHBondContact O-CB 3.49Å; E544-R546 VanDerWaalsContact C-N 3.32Å; E544-R546 PolarHBondContact O-N 2.78Å; R546-A548 PolarHBondContact O-N 3.11Å; R546-Y549 WeakPolarHBondContact O-CB 3.33Å; R546-Y549 PolarHBondContact O-N 3.18Å; R546-E550 WeakPolarHBondContact CD-OE1 3.36Å; R546-E550 HydrophobicContact CG-CG 4.09Å; R546-E550 WeakPolarHBondContact CG-OE1 3.33Å; R546-E550 IonicContact CZ-OE1 2.67Å; R546-E550 IonicContact NE-OE1 3.12Å; R546-E550 IonicContact NH1-OE1 2.69Å; R546-E550 PolarHBondContact NH1-OE1 2.97Å; R546-E550 PolarHBondContact O-N 3.15Å
547C98.5Very high96.3Very high0 Ų031.1 Ų31.10%016%0.161CC..Hα-helixtrans-56-38.1-179.9-69.50000112.4I478 K479 M482 S543 E544 M545 Y549 E550 V551I478-C547 HydrophobicContact CG2-CB 3.94Å; K479-C547 HydrophobicContact CB-CB 4.03Å; K479-C547 HydrophobicContact CG-CB 4.33Å; M482-C547 HydrophobicContact SD-CB 4.43Å; S543-C547 PolarHBondContact O-N 3.21Å; S543-C547 PolarHBondContact O-SG 3.21Å; E544-C547 WeakPolarHBondContact O-CB 3.33Å; E544-C547 PolarHBondContact O-N 3.07Å; M545-C547 VanDerWaalsContact C-N 3.32Å; M545-C547 PolarHBondContact O-N 2.85Å; C547-Y549 VanDerWaalsContact C-N 3.34Å; C547-Y549 PolarHBondContact O-N 3.23Å; C547-E550 PolarHBondContact O-N 3.36Å; C547-V551 WeakPolarHBondContact O-CB 3.33Å; C547-V551 VanDerWaalsContact O-CG2 3.25Å; C547-V551 WeakPolarHBondContact O-CG2 3.44Å; C547-V551 PolarHBondContact O-N 2.7Å
548A98.5Very high96Very high0 Ų031.2 Ų31.20%016%0.161CC..Hα-helixtrans-61.4-40.7176.500000112.5M482 E544 M545 R546 S552 V560 I562M482-A548 HydrophobicContact CE-CB 3.89Å; M482-A548 HydrophobicContact SD-CB 4.41Å; E544-A548 PolarHBondContact O-N 2.95Å; M545-A548 WeakPolarHBondContact O-CB 3.44Å; M545-A548 PolarHBondContact O-N 3.43Å; M545-A548 VanDerWaalsContact O-N 3.15Å; R546-A548 PolarHBondContact O-N 3.11Å; A548-S552 WeakPolarHBondContact O-CB 3.4Å; A548-S552 PolarHBondContact O-N 2.85Å; A548-S552 PolarHBondContact O-OG 2.74Å; A548-V560 HydrophobicContact CB-CB 4.33Å; A548-V560 HydrophobicContact CB-CG1 3.95Å; A548-I562 HydrophobicContact CB-CB 4.03Å; A548-I562 HydrophobicContact CB-CG2 3.57Å
549Y97.7Very high95.8Very high15 Ų1533.6 Ų33.66%0.05917%0.172CC..Hα-helixtrans-66.9-46.6174.5-70.3-87.5000111.9E144 S145 Q146 V147 R293 H294 M545 R546 C547 V551 S552 Q553E144-Y549 WeakPolarHBondContact CB-OH 3.48Å; E144-Y549 WeakPolarHBondContact OE2-CE2 3.48Å; E144-Y549 PolarHBondContact OE2-OH 3.49Å; S145-Y549 PolarHBondContact N-OH 2.94Å; Q146-Y549 HydrophobicContact CB-CD1 4.41Å; Q146-Y549 HydrophobicContact CB-CE1 3.86Å; Q146-Y549 HydrophobicContact CB-CE2 4.25Å; Q146-Y549 HydrophobicContact CG-CD1 4.11Å; Q146-Y549 HydrophobicContact CG-CE1 3.68Å; Q146-Y549 PolarHBondContact N-OH 3.08Å; Q146-Y549 VanDerWaalsContact OE1-CE1 3.3Å; V147-Y549 HydrophobicContact CG2-CE2 3.94Å; R293-Y549 PolarHBondContact NH2-OH 2.83Å; H294-Y549 AromaticContact CD2-CD2 3.83Å; H294-Y549 AromaticContact CD2-CG 3.92Å; H294-Y549 AromaticContact CE1-CD2 3.8Å; H294-Y549 AromaticContact CE1-CE2 3.9Å; H294-Y549 AromaticContact NE2-CD2 3.19Å; H294-Y549 WeakPolarHBondContact NE2-CD2 3.43Å; H294-Y549 AromaticContact NE2-CE2 3.32Å; H294-Y549 VanDerWaalsContact NE2-CE2 3.32Å; H294-Y549 WeakPolarHBondContact NE2-CE2 3.36Å; H294-Y549 AromaticContact NE2-CG 3.7Å; H294-Y549 AromaticContact NE2-CZ 3.92Å; M545-Y549 VanDerWaalsContact O-CD2 3.25Å; M545-Y549 WeakPolarHBondContact O-CD2 3.17Å; R546-Y549 WeakPolarHBondContact O-CB 3.33Å; R546-Y549 PolarHBondContact O-N 3.18Å; C547-Y549 VanDerWaalsContact C-N 3.34Å; C547-Y549 PolarHBondContact O-N 3.23Å; Y549-V551 VanDerWaalsContact C-N 3.34Å; Y549-V551 PolarHBondContact O-N 3.46Å; Y549-S552 PolarHBondContact O-N 3.41Å; Y549-Q553 WeakPolarHBondContact O-CB 3.22Å; Y549-Q553 VanDerWaalsContact O-CG 3.24Å; Y549-Q553 WeakPolarHBondContact O-CG 3.14Å; Y549-Q553 PolarHBondContact O-N 2.99Å
550E97.1Very high95.8Very high51 Ų5133.6 Ų33.624%0.23817%0.172CC..Hα-helixtrans-58.5-46.6179-70.5-178.9-17900111.3K479 R546 C547 Q553 A554K479-E550 WeakPolarHBondContact CE-OE2 3.41Å; K479-E550 IonicContact NZ-OE2 2.69Å; K479-E550 PolarHBondContact NZ-OE2 2.74Å; R546-E550 WeakPolarHBondContact CD-OE1 3.36Å; R546-E550 HydrophobicContact CG-CG 4.09Å; R546-E550 WeakPolarHBondContact CG-OE1 3.33Å; R546-E550 IonicContact CZ-OE1 2.67Å; R546-E550 IonicContact NE-OE1 3.12Å; R546-E550 IonicContact NH1-OE1 2.69Å; R546-E550 PolarHBondContact NH1-OE1 2.97Å; R546-E550 PolarHBondContact O-N 3.15Å; C547-E550 PolarHBondContact O-N 3.36Å; E550-Q553 PolarHBondContact O-N 3.32Å; E550-A554 WeakPolarHBondContact O-CB 3.38Å; E550-A554 PolarHBondContact O-N 2.8Å
551V97.3Very high95.7Very high2 Ų233.7 Ų33.71%0.01217%0.173CC..Hα-helixtrans-65.5-42.9179.1174.70000111.1K479 M482 E483 I486 C547 Y549 Q553 A554 H555 V560K479-V551 HydrophobicContact CG-CG2 3.74Å; M482-V551 HydrophobicContact CB-CB 4.49Å; M482-V551 HydrophobicContact CB-CG1 4.08Å; M482-V551 HydrophobicContact CB-CG2 4.13Å; M482-V551 HydrophobicContact SD-CG2 4.21Å; E483-V551 HydrophobicContact CG-CG2 4.21Å; I486-V551 HydrophobicContact CD1-CG1 3.39Å; C547-V551 WeakPolarHBondContact O-CB 3.33Å; C547-V551 VanDerWaalsContact O-CG2 3.25Å; C547-V551 WeakPolarHBondContact O-CG2 3.44Å; C547-V551 PolarHBondContact O-N 2.7Å; Y549-V551 VanDerWaalsContact C-N 3.34Å; Y549-V551 PolarHBondContact O-N 3.46Å; V551-Q553 VanDerWaalsContact C-N 3.3Å; V551-Q553 PolarHBondContact O-N 3.22Å; V551-A554 PolarHBondContact O-N 2.96Å; V551-H555 WeakPolarHBondContact O-CB 3.39Å; V551-H555 PolarHBondContact O-CD2 2.63Å; V551-H555 PolarHBondContact O-N 3.39Å; V551-V560 HydrophobicContact CB-CG2 4.23Å; V551-V560 HydrophobicContact CG1-CG2 3.76Å
552S95.6Very high95.8Very high17 Ų1733.3 Ų33.312%0.11917%0.17CC..Hα-helixtrans-64.4-35.2177.8-57.40000112.7Q146 A548 Y549 H555 V560Q146-S552 VanDerWaalsContact NE2-CB 3.32Å; Q146-S552 PolarHBondContact NE2-OG 2.94Å; A548-S552 WeakPolarHBondContact O-CB 3.4Å; A548-S552 PolarHBondContact O-N 2.85Å; A548-S552 PolarHBondContact O-OG 2.74Å; Y549-S552 PolarHBondContact O-N 3.41Å; S552-H555 CarbonylContact O-C 3.57Å; S552-V560 WeakPolarHBondContact OG-CB 3.26Å; S552-V560 PolarHBondContact OG-N 2.6Å
553Q94.2Very high95.8Very high142 Ų14232.3 Ų32.366%0.66417%0.166SC*.Hα-helixtrans-69.4-38.2175.4-72.9174.311.700112Y549 E550 V551Y549-Q553 WeakPolarHBondContact O-CB 3.22Å; Y549-Q553 VanDerWaalsContact O-CG 3.24Å; Y549-Q553 WeakPolarHBondContact O-CG 3.14Å; Y549-Q553 PolarHBondContact O-N 2.99Å; E550-Q553 PolarHBondContact O-N 3.32Å; V551-Q553 VanDerWaalsContact C-N 3.3Å; V551-Q553 PolarHBondContact O-N 3.22Å
554A93.8Very high95.8Very high76 Ų7632 Ų3263%0.62816%0.164SC*.Hα-helixtrans-71.4-41.2176.700000112.3E550 V551E550-A554 WeakPolarHBondContact O-CB 3.38Å; E550-A554 PolarHBondContact O-N 2.8Å; V551-A554 PolarHBondContact O-N 2.96Å
555H91.5Very high95.8Very high42 Ų4232 Ų3219%0.19416%0.164CC..  trans-106.674.5-177.5-63.4-94.3000111.4I486 D487 V551 S552 S557 C558I486-H555 HydrophobicContact CD1-CB 3.99Å; I486-H555 HydrophobicContact CG2-CB 4.29Å; D487-H555 IonicContact OD1-CE1 3.04Å; V551-H555 WeakPolarHBondContact O-CB 3.39Å; V551-H555 PolarHBondContact O-CD2 2.63Å; V551-H555 PolarHBondContact O-N 3.39Å; S552-H555 CarbonylContact O-C 3.57Å; H555-S557 PolarHBondContact O-N 3.42Å; H555-C558 CarbonylContact O-C 3.45Å; H555-C558 PolarHBondContact O-N 3.45Å
556K86.3Confident95.7Very high195 Ų19533.2 Ų33.285%0.84817%0.17SC*.THydrogen-bonded Turntrans-57.8-15.7-176.6-61.9-177.4-178.2176.10115.5
557S87.3Confident95.7Very high43 Ų4332.8 Ų32.830%0.30117%0.17SC..THydrogen-bonded Turntrans-80-17.2174.554.90000113.6G507 G529 S530 H555G507-S557 PolarHBondContact O-OG 3.15Å; G529-S557 CarbonylContact C-O 3.5Å; G529-S557 WeakPolarHBondContact CA-O 3.46Å; S530-S557 PolarHBondContact N-O 3.2Å; H555-S557 PolarHBondContact O-N 3.42Å
558C92Very high95.6Very high2 Ų233 Ų331%0.01417%0.171CC..EExtended strand (participates in β ladder)trans-134.1119.4-175.7-170.60000112.2I486 S530 H555I486-C558 HydrophobicContact CD1-CB 4.18Å; I486-C558 HydrophobicContact CG1-CB 4.17Å; I486-C558 HydrophobicContact CG2-CB 4.33Å; S530-C558 CarbonylContact O-C 3.56Å; S530-C558 WeakPolarHBondContact O-CA 3.19Å; S530-C558 PolarHBondContact O-SG 3.39Å; H555-C558 CarbonylContact O-C 3.45Å; H555-C558 PolarHBondContact O-N 3.45Å
559E94.6Very high95.6Very high51 Ų5133.8 Ų33.824%0.23818%0.176CC..EExtended strand (participates in β ladder)trans-84.8126.3171.3178.6179.3-136.700109.7S530 R531 L532 I561S530-E559 PolarHBondContact O-N 2.89Å; R531-E559 WeakPolarHBondContact CA-O 3.4Å; R531-E559 HydrophobicContact CG-CB 4.43Å; R531-E559 IonicContact NE-OE2 3.12Å; R531-E559 PolarHBondContact NE-OE2 2.86Å; R531-E559 VanDerWaalsContact NE-OE2 3.13Å; L532-E559 PolarHBondContact N-O 2.78Å; E559-I561 HydrophobicContact CG-CG1 4.13Å
560V97.5Very high95.6Very high0 Ų033.9 Ų33.90%018%0.178CC..EExtended strand (participates in β ladder)trans-96.4125.9174-172.80000109.4Q146 M482 I486 L532 I534 A548 V551 S552Q146-V560 PolarHBondContact NE2-O 3.05Å; M482-V560 HydrophobicContact CE-CG1 3.98Å; M482-V560 HydrophobicContact CG-CG1 4.14Å; M482-V560 HydrophobicContact SD-CG1 3.97Å; I486-V560 HydrophobicContact CD1-CG2 4.06Å; L532-V560 HydrophobicContact CB-CG2 4.33Å; L532-V560 HydrophobicContact CD2-CG1 4.45Å; L532-V560 HydrophobicContact CD2-CG2 4.29Å; L532-V560 CarbonylContact O-C 3.59Å; L532-V560 VanDerWaalsContact O-CA 3.32Å; L532-V560 WeakPolarHBondContact O-CA 2.98Å; I534-V560 HydrophobicContact CG1-CG1 4.15Å; A548-V560 HydrophobicContact CB-CB 4.33Å; A548-V560 HydrophobicContact CB-CG1 3.95Å; V551-V560 HydrophobicContact CB-CG2 4.23Å; V551-V560 HydrophobicContact CG1-CG2 3.76Å; S552-V560 WeakPolarHBondContact OG-CB 3.26Å; S552-V560 PolarHBondContact OG-N 2.6Å
561I98.1Very high95.5Very high2 Ų237.9 Ų37.91%0.0119%0.191CC..EExtended strand (participates in β ladder)trans-118.7119.2174.5-59.6178.2000107.4L10 Q146 Y148 L188 L532 I533 I534 E559L10-I561 HydrophobicContact CD2-CG2 4.34Å; Q146-I561 WeakPolarHBondContact O-CA 3.16Å; Y148-I561 HydrophobicContact CD1-CG2 3.67Å; Y148-I561 HydrophobicContact CE1-CG2 3.89Å; L188-I561 HydrophobicContact CD1-CD1 3.7Å; L188-I561 HydrophobicContact CD2-CD1 3.56Å; L188-I561 HydrophobicContact CG-CD1 4.29Å; L532-I561 PolarHBondContact O-N 2.85Å; I533-I561 CarbonylContact C-O 3.55Å; I533-I561 WeakPolarHBondContact CA-O 3.45Å; I534-I561 PolarHBondContact N-O 3.26Å; E559-I561 HydrophobicContact CG-CG1 4.13Å
562I98.7Very high95.5Very high0 Ų043.4 Ų43.40%022%0.215CC..EExtended strand (participates in β ladder)trans-108.7141.1-177.6-173.9173.8000110.7Q146 V147 Y148 I478 M482 I534 I540 E544 A548Q146-I562 PolarHBondContact O-N 3.41Å; V147-I562 CarbonylContact C-O 3.4Å; V147-I562 VanDerWaalsContact CA-O 3.23Å; V147-I562 WeakPolarHBondContact CA-O 3.38Å; V147-I562 HydrophobicContact CG2-CG2 3.94Å; Y148-I562 VanDerWaalsContact CD1-O 3.31Å; Y148-I562 WeakPolarHBondContact CD1-O 3.26Å; Y148-I562 PolarHBondContact N-O 2.99Å; I478-I562 HydrophobicContact CD1-CD1 3.58Å; M482-I562 HydrophobicContact CE-CB 4.44Å; M482-I562 HydrophobicContact CE-CD1 3.87Å; I534-I562 HydrophobicContact CB-CB 4.36Å; I534-I562 HydrophobicContact CB-CG1 4.14Å; I534-I562 HydrophobicContact CG2-CG1 4.23Å; I534-I562 CarbonylContact O-C 3.59Å; I540-I562 HydrophobicContact CD1-CG1 4.25Å; I540-I562 HydrophobicContact CG2-CD1 4.07Å; I540-I562 HydrophobicContact CG2-CG1 4.29Å; E544-I562 HydrophobicContact CB-CD1 4.14Å; A548-I562 HydrophobicContact CB-CB 4.03Å; A548-I562 HydrophobicContact CB-CG2 3.57Å
563G98.7Very high95.6Very high0 Ų042.6 Ų42.60%021%0.21CC..EExtended strand (participates in β ladder)trans-153.7175.4171.300000114.1Y148 I534 F535 V536Y148-G563 VanDerWaalsContact CE1-N 3.35Å; Y148-G563 WeakPolarHBondContact O-CA 3.32Å; I534-G563 PolarHBondContact O-N 3.49Å; F535-G563 WeakPolarHBondContact CA-O 3.2Å; V536-G563 PolarHBondContact N-O 3.2Å
564S98.7Very high95.8Very high0 Ų035.9 Ų35.90%018%0.178CC..EExtended strand (participates in β ladder)trans-161.2-177.4-174.7-163.80000112.1Y148 T149 L150 F535 V536 G539 I540 H566Y148-S564 PolarHBondContact O-N 3.32Å; T149-S564 CarbonylContact C-O 3.55Å; T149-S564 VanDerWaalsContact CA-O 3.27Å; T149-S564 WeakPolarHBondContact CA-O 3.19Å; L150-S564 PolarHBondContact N-O 3.06Å; F535-S564 VanDerWaalsContact CE2-C 3.43Å; F535-S564 VanDerWaalsContact CE2-CA 3.42Å; V536-S564 WeakPolarHBondContact O-CA 3.25Å; V536-S564 WeakPolarHBondContact O-CB 3.38Å; V536-S564 PolarHBondContact O-OG 3.2Å; G539-S564 WeakPolarHBondContact CA-OG 3.4Å; G539-S564 PolarHBondContact N-OG 3.45Å; I540-S564 PolarHBondContact N-OG 2.96Å; S564-H566 VanDerWaalsContact C-N 3.3Å
565T98.2Very high96Very high0 Ų036 Ų360%017%0.168CC..SBendtrans-64.5-37.117359.20000111.6D151 V152 A155 M177 F535 G538 G539D151-T565 WeakPolarHBondContact CA-O 3.37Å; D151-T565 PolarHBondContact N-O 3.33Å; V152-T565 HydrophobicContact CG2-CG2 3.91Å; V152-T565 PolarHBondContact N-O 2.85Å; A155-T565 HydrophobicContact CB-CG2 3.73Å; M177-T565 HydrophobicContact SD-CG2 3.46Å; M177-T565 WeakPolarHBondContact SD-CG2 3.26Å; F535-T565 HydrophobicContact CZ-CG2 4.02Å; G538-T565 WeakPolarHBondContact CA-OG1 3.48Å; G538-T565 PolarHBondContact N-OG1 3.44Å; G539-T565 PolarHBondContact N-OG1 2.81Å
566H97.9Very high96.2Very high25 Ų2536.7 Ų36.712%0.11617%0.173CC..SBendtrans-165.3-179.6177.563-63.3000110.6P153 G539 I540 S564 L568P153-H566 HydrophobicContact CB-CB 4.26Å; G539-H566 VanDerWaalsContact CA-O 3.25Å; G539-H566 WeakPolarHBondContact CA-O 3.45Å; I540-H566 PolarHBondContact N-O 2.97Å; I540-H566 VanDerWaalsContact N-O 3.17Å; S564-H566 VanDerWaalsContact C-N 3.3Å; H566-L568 WeakPolarHBondContact NE2-CD2 3.42Å
567I98Very high96.8Very high26 Ų2627.4 Ų27.413%0.13313%0.133CC..EExtended strand (participates in β ladder)trans-103.6134.9175.3-61.6168000109.7H143 T149 I540 Y542 M545H143-I567 HydrophobicContact CB-CD1 4.31Å; H143-I567 WeakPolarHBondContact CD2-CD1 2.99Å; H143-I567 WeakPolarHBondContact NE2-CD1 3.32Å; T149-I567 HydrophobicContact CG2-CD1 4.15Å; T149-I567 HydrophobicContact CG2-CG1 3.87Å; I540-I567 HydrophobicContact CG1-CG1 4.27Å; I540-I567 CarbonylContact O-C 3.56Å; I540-I567 WeakPolarHBondContact O-CA 3.42Å; Y542-I567 HydrophobicContact CD1-CG2 4.4Å; Y542-I567 HydrophobicContact CD2-CG2 4.3Å; Y542-I567 HydrophobicContact CE1-CG2 3.9Å; Y542-I567 HydrophobicContact CE2-CG2 3.77Å; M545-I567 HydrophobicContact CE-CD1 4.2Å; M545-I567 HydrophobicContact SD-CD1 3.89Å; M545-I567 HydrophobicContact SD-CG1 4.14Å; M545-I567 HydrophobicContact SD-CG2 4.07Å
568L97Very high97.3Very high3 Ų327.1 Ų27.12%0.01613%0.126CC..EExtended strand (participates in β ladder)trans-99.1142-176.4-64.7169.7000111.6I540 H566 L573I540-L568 PolarHBondContact O-N 3.23Å; H566-L568 WeakPolarHBondContact NE2-CD2 3.42Å; L568-L573 HydrophobicContact CD1-CD1 4.06Å; L568-L573 HydrophobicContact CD1-CD2 4.38Å; L568-L573 HydrophobicContact CD2-CB 4.13Å; L568-L573 HydrophobicContact CD2-CD1 4.05Å
569T97.4Very high97.5Very high18 Ų1829.5 Ų29.511%0.1114%0.138CC..  trans-112.5150.6156.256.50000107.5Y259 Y542 R571 K572 L573Y259-T569 WeakPolarHBondContact O-CG2 3.35Å; Y542-T569 HydrophobicContact CE2-CG2 4.2Å; T569-R571 VanDerWaalsContact C-N 3.26Å; T569-R571 PolarHBondContact O-N 3.31Å; T569-R571 VanDerWaalsContact O-N 3.15Å; T569-K572 PolarHBondContact O-N 3.36Å; T569-K572 WeakPolarHBondContact OG1-CB 3.49Å; T569-K572 WeakPolarHBondContact OG1-CD 3.49Å; T569-K572 VanDerWaalsContact OG1-CG 3.29Å; T569-K572 WeakPolarHBondContact OG1-CG 3.26Å; T569-L573 PolarHBondContact O-N 3.42Å
570P97.5Very high97.6Very high16 Ų1627.1 Ų27.110%0.10413%0.127CC..Hα-helixtrans-49.7-45.4-178.9-30.737.2000113.5D260 L573 L574D260-P570 WeakPolarHBondContact OD1-CG 3.49Å; P570-L573 PolarHBondContact O-N 3.48Å; P570-L574 WeakPolarHBondContact O-CG 3.38Å; P570-L574 PolarHBondContact O-N 2.88Å
571R96.3Very high97.5Very high136 Ų13630.4 Ų30.451%0.51314%0.144SC..Hα-helixtrans-60.2-53.5179.4-170173.1-66-119.4-6.7113.1D400 T569 L573 L574 D575D400-R571 IonicContact OD2-NH2 2.65Å; D400-R571 PolarHBondContact OD2-NH2 2.7Å; T569-R571 VanDerWaalsContact C-N 3.26Å; T569-R571 PolarHBondContact O-N 3.31Å; T569-R571 VanDerWaalsContact O-N 3.15Å; R571-L573 VanDerWaalsContact C-N 3.29Å; R571-L573 PolarHBondContact O-N 2.74Å; R571-L574 PolarHBondContact O-N 3.19Å; R571-L574 VanDerWaalsContact O-N 3.16Å; R571-D575 PolarHBondContact O-N 3.16Å
572K96.1Very high97.2Very high117 Ų11733.5 Ų33.551%0.50916%0.158SC..Hα-helixtrans-57.5-41.6177.3-69.9178.1-176.3173.10112.4T569 D575 D576T569-K572 PolarHBondContact O-N 3.36Å; T569-K572 WeakPolarHBondContact OG1-CB 3.49Å; T569-K572 WeakPolarHBondContact OG1-CD 3.49Å; T569-K572 VanDerWaalsContact OG1-CG 3.29Å; T569-K572 WeakPolarHBondContact OG1-CG 3.26Å; K572-D575 PolarHBondContact O-N 3.31Å; K572-D576 PolarHBondContact O-N 2.83Å
573L98Very high96.3Very high1 Ų135.4 Ų35.41%0.00517%0.171CC..Hα-helixtrans-62.5-45.5177.4177.763.5000111.6F156 T247 W442 L568 T569 P570 R571 D575 D576 I577F156-L573 HydrophobicContact CE2-CD1 3.67Å; F156-L573 HydrophobicContact CZ-CD1 3.66Å; T247-L573 VanDerWaalsContact CB-CD2 3.4Å; T247-L573 HydrophobicContact CG2-CD2 3.93Å; W442-L573 HydrophobicContact CH2-CD2 3.84Å; W442-L573 HydrophobicContact CZ2-CD2 4.06Å; L568-L573 HydrophobicContact CD1-CD1 4.06Å; L568-L573 HydrophobicContact CD1-CD2 4.38Å; L568-L573 HydrophobicContact CD2-CB 4.13Å; L568-L573 HydrophobicContact CD2-CD1 4.05Å; T569-L573 PolarHBondContact O-N 3.42Å; P570-L573 PolarHBondContact O-N 3.48Å; R571-L573 VanDerWaalsContact C-N 3.29Å; R571-L573 PolarHBondContact O-N 2.74Å; L573-D575 VanDerWaalsContact C-N 3.3Å; L573-D575 PolarHBondContact O-N 3.1Å; L573-D576 PolarHBondContact O-N 3.48Å; L573-I577 HydrophobicContact CD1-CD1 3.92Å; L573-I577 HydrophobicContact CD1-CG1 4.09Å; L573-I577 HydrophobicContact CD2-CD1 4.35Å; L573-I577 HydrophobicContact CG-CD1 3.8Å; L573-I577 HydrophobicContact CG-CG1 4.32Å; L573-I577 WeakPolarHBondContact O-CB 3.44Å; L573-I577 VanDerWaalsContact O-CG1 3.28Å; L573-I577 WeakPolarHBondContact O-CG1 3.22Å; L573-I577 PolarHBondContact O-N 2.95Å
574L98.3Very high95.1Very high1 Ų137.4 Ų37.41%0.00518%0.18CC..Hα-helixtrans-62.8-39.4178.9-68.7175.7000111.4V248 I405 R406 L409 M438 P570 R571 I577 K578V248-L574 HydrophobicContact CG1-CD2 4.36Å; I405-L574 HydrophobicContact CG2-CD1 4.28Å; I405-L574 HydrophobicContact CG2-CD2 4.35Å; R406-L574 HydrophobicContact CG-CD1 4.03Å; L409-L574 HydrophobicContact CD1-CD2 3.53Å; M438-L574 HydrophobicContact CB-CD2 4.48Å; M438-L574 HydrophobicContact CE-CB 4.32Å; M438-L574 HydrophobicContact CG-CB 4.4Å; M438-L574 HydrophobicContact SD-CB 3.97Å; P570-L574 WeakPolarHBondContact O-CG 3.38Å; P570-L574 PolarHBondContact O-N 2.88Å; R571-L574 PolarHBondContact O-N 3.19Å; R571-L574 VanDerWaalsContact O-N 3.16Å; L574-I577 PolarHBondContact O-N 3.41Å; L574-K578 WeakPolarHBondContact O-CB 3.38Å; L574-K578 PolarHBondContact O-N 2.88Å
575D97Very high93.4Very high77 Ų7742 Ų4241%0.41220%0.204SC..Hα-helixtrans-60.8-45.9173.3-66.1-30.4000111.5M438 R571 K572 L573 I577 K578 M579M438-D575 WeakPolarHBondContact CE-OD1 3.45Å; R571-D575 PolarHBondContact O-N 3.16Å; K572-D575 PolarHBondContact O-N 3.31Å; L573-D575 VanDerWaalsContact C-N 3.3Å; L573-D575 PolarHBondContact O-N 3.1Å; D575-I577 PolarHBondContact O-N 3.32Å; D575-K578 WeakPolarHBondContact O-CB 3.37Å; D575-K578 PolarHBondContact O-N 3.07Å; D575-M579 WeakPolarHBondContact O-CG 3.28Å; D575-M579 PolarHBondContact O-N 3.19Å
576D97.3Very high90.9Very high57 Ų5749.4 Ų49.431%0.30524%0.237SC..Hα-helixtrans-64.6-40.5177.9-73.1-26.1000112.1F156 K572 L573 M579 L580F156-D576 HydrophobicContact CD1-CB 3.67Å; F156-D576 HydrophobicContact CE1-CB 3.72Å; F156-D576 HydrophobicContact CG-CB 4.5Å; K572-D576 PolarHBondContact O-N 2.83Å; L573-D576 PolarHBondContact O-N 3.48Å; D576-M579 PolarHBondContact O-N 3.35Å; D576-L580 PolarHBondContact O-N 3.09Å
577I98.3Very high88.5Confident0 Ų049.6 Ų49.60%024%0.239CC..Hα-helixtrans-62.7-43.1175.5-72.4176.6000110.8F156 N441 W442 L573 L574 D575 M579 L580F156-I577 HydrophobicContact CE1-CG1 3.98Å; F156-I577 HydrophobicContact CZ-CD1 4.43Å; F156-I577 HydrophobicContact CZ-CG1 3.62Å; N441-I577 HydrophobicContact CB-CG2 3.72Å; N441-I577 VanDerWaalsContact CB-O 3.3Å; N441-I577 WeakPolarHBondContact CB-O 3.34Å; N441-I577 PolarHBondContact ND2-O 3.07Å; W442-I577 HydrophobicContact CD2-CD1 3.72Å; W442-I577 HydrophobicContact CE3-CD1 4.23Å; W442-I577 HydrophobicContact CG-CD1 4.28Å; W442-I577 HydrophobicContact CH2-CD1 3.8Å; W442-I577 HydrophobicContact CZ2-CD1 3.25Å; W442-I577 HydrophobicContact CZ3-CD1 4.27Å; L573-I577 HydrophobicContact CD1-CD1 3.92Å; L573-I577 HydrophobicContact CD1-CG1 4.09Å; L573-I577 HydrophobicContact CD2-CD1 4.35Å; L573-I577 HydrophobicContact CG-CD1 3.8Å; L573-I577 HydrophobicContact CG-CG1 4.32Å; L573-I577 WeakPolarHBondContact O-CB 3.44Å; L573-I577 VanDerWaalsContact O-CG1 3.28Å; L573-I577 WeakPolarHBondContact O-CG1 3.22Å; L573-I577 PolarHBondContact O-N 2.95Å; L574-I577 PolarHBondContact O-N 3.41Å; D575-I577 PolarHBondContact O-N 3.32Å; I577-M579 PolarHBondContact O-N 2.89Å; I577-M579 VanDerWaalsContact O-N 3.12Å; I577-L580 HydrophobicContact CG1-CD1 4.48Å; I577-L580 PolarHBondContact O-N 3.43Å; I577-L580 VanDerWaalsContact O-N 3.17Å
578K97.4Very high85.8Confident38 Ų3851.9 Ų51.917%0.16526%0.257CS..Hα-helixtrans-56.5-28.5176.4-163.3-179.4176.8168.70112.5D434 D435 D437 M438 L574 D575 K582D434-K578 WeakPolarHBondContact O-CE 3.42Å; D434-K578 PolarHBondContact O-NZ 3.27Å; D435-K578 IonicContact OD1-NZ 2.81Å; D435-K578 PolarHBondContact OD1-NZ 3.04Å; D437-K578 HydrophobicContact CB-CG 3.88Å; M438-K578 HydrophobicContact CE-CB 4.35Å; M438-K578 HydrophobicContact CE-CD 3.8Å; M438-K578 HydrophobicContact CG-CB 3.75Å; M438-K578 HydrophobicContact CG-CD 4.08Å; M438-K578 HydrophobicContact CG-CG 3.97Å; L574-K578 WeakPolarHBondContact O-CB 3.38Å; L574-K578 PolarHBondContact O-N 2.88Å; D575-K578 WeakPolarHBondContact O-CB 3.37Å; D575-K578 PolarHBondContact O-N 3.07Å; K578-K582 WeakPolarHBondContact O-CE 3.47Å
579M96Very high82.6Confident52 Ų5259 Ų5926%0.25629%0.289SS..Hα-helixtrans-90.4-10.4-176.1-64.5-59.1116.900114.3Y157 D575 D576 I577 N581 K582 V587Y157-M579 WeakPolarHBondContact CE2-O 3.49Å; D575-M579 WeakPolarHBondContact O-CG 3.28Å; D575-M579 PolarHBondContact O-N 3.19Å; D576-M579 PolarHBondContact O-N 3.35Å; I577-M579 PolarHBondContact O-N 2.89Å; I577-M579 VanDerWaalsContact O-N 3.12Å; M579-N581 VanDerWaalsContact C-N 3.33Å; M579-N581 PolarHBondContact O-N 3.02Å; M579-K582 HydrophobicContact CE-CD 4Å; M579-K582 WeakPolarHBondContact O-CB 3.45Å; M579-K582 PolarHBondContact O-N 3.19Å; M579-K582 HydrophobicContact SD-CD 3.87Å; M579-V587 HydrophobicContact SD-CG2 4.39Å
580L97.1Very high79.5Confident1 Ų163.6 Ų63.61%0.00531%0.312CS..THydrogen-bonded Turntrans-58.6-39.2-170.9-73.1176.3000114.4F156 Y157 P162 N441 H444 L445 D576 I577 K582F156-L580 HydrophobicContact CD1-CD2 3.97Å; F156-L580 HydrophobicContact CE1-CD1 3.99Å; F156-L580 HydrophobicContact CE1-CD2 3.78Å; F156-L580 HydrophobicContact CE1-CG 4.05Å; F156-L580 HydrophobicContact CZ-CD1 4.39Å; Y157-L580 HydrophobicContact CD2-CD2 4.46Å; P162-L580 WeakPolarHBondContact CD-O 3.39Å; N441-L580 HydrophobicContact CB-CB 4.3Å; N441-L580 HydrophobicContact CB-CD1 4.27Å; H444-L580 HydrophobicContact CB-CD1 4.44Å; L445-L580 HydrophobicContact CD1-CD1 3.5Å; L445-L580 VanDerWaalsContact CD1-CD1 3.5Å; D576-L580 PolarHBondContact O-N 3.09Å; I577-L580 HydrophobicContact CG1-CD1 4.48Å; I577-L580 PolarHBondContact O-N 3.43Å; I577-L580 VanDerWaalsContact O-N 3.17Å; L580-K582 VanDerWaalsContact C-N 3.32Å
581N94.6Very high76.4Confident69 Ų6971.2 Ų71.237%0.36934%0.344SS..THydrogen-bonded Turntrans-895.9178.963.8-9.1000113.4D437 N441 M579D437-N581 PolarHBondContact OD1-ND2 3.33Å; N441-N581 VanDerWaalsContact ND2-CG 3.31Å; N441-N581 PolarHBondContact ND2-OD1 3.02Å; N441-N581 VanDerWaalsContact ND2-OD1 3.1Å; N441-N581 PolarHBondContact OD1-ND2 3.35Å; M579-N581 VanDerWaalsContact C-N 3.33Å; M579-N581 PolarHBondContact O-N 3.02Å
582K91.9Very high73.2Confident67 Ų6772 Ų7229%0.29136%0.358SS..SBendtrans-104137.3180-59.2179.8-175172.30109.7Y157 D437 K578 M579 L580 K584Y157-K582 VanDerWaalsContact CE2-O 3.29Å; Y157-K582 WeakPolarHBondContact CE2-O 3.46Å; Y157-K582 PolarHBondContact OH-O 3.27Å; D437-K582 WeakPolarHBondContact OD2-CE 3.5Å; D437-K582 IonicContact OD2-NZ 3.46Å; D437-K582 PolarHBondContact OD2-NZ 3.39Å; K578-K582 WeakPolarHBondContact O-CE 3.47Å; M579-K582 HydrophobicContact CE-CD 4Å; M579-K582 WeakPolarHBondContact O-CB 3.45Å; M579-K582 PolarHBondContact O-N 3.19Å; M579-K582 HydrophobicContact SD-CD 3.87Å; L580-K582 VanDerWaalsContact C-N 3.32Å; K582-K584 PolarHBondContact O-N 3.04Å
583S81.3Confident70Confident39 Ų3977.1 Ų77.127%0.27338%0.383SS..  trans-68.4124.5177176.80000110.4D585 K586S583-D585 PolarHBondContact O-N 3.47Å; S583-K586 WeakPolarHBondContact O-CB 3.35Å; S583-K586 PolarHBondContact O-N 3.29Å
584K71.9Confident68.6Low42 Ų4280.9 Ų80.918%0.18340%0.402CS..Hα-helixtrans-57.8-30.4178.6-106-172.8177-174.70113.7D154 Y157 Y158 K582 K586 V587 S588D154-K584 IonicContact OD1-NZ 2.96Å; D154-K584 PolarHBondContact OD1-NZ 3.13Å; D154-K584 IonicContact OD2-NZ 3.73Å; Y157-K584 HydrophobicContact CD1-CD 3.52Å; Y157-K584 HydrophobicContact CD1-CG 3.95Å; Y157-K584 HydrophobicContact CD2-CG 4.39Å; Y157-K584 HydrophobicContact CE1-CB 4Å; Y157-K584 HydrophobicContact CE1-CD 3.63Å; Y157-K584 HydrophobicContact CE1-CG 3.65Å; Y157-K584 HydrophobicContact CE2-CG 4.13Å; Y157-K584 HydrophobicContact CG-CD 4.05Å; Y157-K584 HydrophobicContact CG-CG 4.3Å; Y157-K584 PolarHBondContact OH-N 3.01Å; Y157-K584 VanDerWaalsContact OH-N 3.15Å; Y158-K584 HydrophobicContact CE1-CD 4.19Å; K582-K584 PolarHBondContact O-N 3.04Å; K584-K586 PolarHBondContact O-N 3.32Å; K584-V587 WeakPolarHBondContact O-CB 3.12Å; K584-V587 PolarHBondContact O-N 3.41Å; K584-S588 PolarHBondContact O-N 2.74Å
585D63.6Low67Low98 Ų9885.1 Ų85.152%0.52442%0.423SS..Hα-helixtrans-66.7-18.6177.8-61.4-18.6000111.8R169 S583 F589R169-D585 IonicContact NH1-OD1 3.96Å; R169-D585 IonicContact NH2-OD1 2.81Å; S583-D585 PolarHBondContact O-N 3.47Å; D585-F589 WeakPolarHBondContact O-CD2 3.21Å; D585-F589 VanDerWaalsContact O-CE2 3.32Å; D585-F589 WeakPolarHBondContact O-CE2 3.3Å
586K46.8Very low65.4Low155 Ų15585.6 Ų85.667%0.67442%0.424SS*.Hα-helixtrans-88.4-16.6170-63.4-176.2177.2-178.50113.3S583 K584S583-K586 WeakPolarHBondContact O-CB 3.35Å; S583-K586 PolarHBondContact O-N 3.29Å; K584-K586 PolarHBondContact O-N 3.32Å
587V46.1Very low63.5Low28 Ų2887.2 Ų87.217%0.1743%0.431CS..Hα-helixtrans-86-29.1-172.6178.40000112.4M579 K584 F589 L590M579-V587 HydrophobicContact SD-CG2 4.39Å; K584-V587 WeakPolarHBondContact O-CB 3.12Å; K584-V587 PolarHBondContact O-N 3.41Å; V587-F589 PolarHBondContact O-N 3.41Å; V587-F589 VanDerWaalsContact O-N 3.16Å; V587-L590 PolarHBondContact O-N 3.27Å
588S41.5Very low61.3Low74 Ų7492.7 Ų92.752%0.51746%0.458SS..THydrogen-bonded Turntrans-58.5-24.4169.647.30000112.4K584K584-S588 PolarHBondContact O-N 2.74Å
589F29.7Very low58.9Low153 Ų15396.3 Ų96.367%0.67148%0.477SS*.THydrogen-bonded Turntrans-80.2-17175.3-65.3-81.6000114.3D585 V587D585-F589 WeakPolarHBondContact O-CD2 3.21Å; D585-F589 VanDerWaalsContact O-CE2 3.32Å; D585-F589 WeakPolarHBondContact O-CE2 3.3Å; V587-F589 PolarHBondContact O-N 3.41Å; V587-F589 VanDerWaalsContact O-N 3.16Å
590L33.1Very low56.3Low114 Ų11499.5 Ų99.560%0.59749%0.493SS*.THydrogen-bonded Turntrans-96.5-9.5-177.5-72.4169.6000113.9V587V587-L590 PolarHBondContact O-N 3.27Å
591K32.1Very low53.1Low177 Ų177107.1 Ų107.177%0.7753%0.531SS*.SBendtrans-95-9175-78.2-173.3175.5179.90113.6
592D28.4Very low49.7Very low151 Ų151110.3 Ų110.381%0.80754%0.544SS*.  trans-104.76.3179.9-73.5-14.5000113.1
593E29.8Very low45.8Very low225 Ų225114.2 Ų114.2100%1.05157%0.567SS**  trans-108.20163.8-68.9-172.6166.400109.8

Retrieved 593 of 593 residues in 1405.3 ms (Link to these results)