SLAH2_ARATH Loading...

S-type anion channel SLAH2

Slow, weak voltage-dependent S-type anion efflux channel involved in maintenance of anion homeostasis.

AlphaFold DB , UniProt , Accession Q9ASQ7, Species ARATH (Arabidopsis thaliana, Mouse-ear cress), Gene SLAH2, Length 519 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	33	Very low	32.8	Very low	240 Å²	240	154.7 Å²	154.7	100%	1.182	86%	0.856	S	S	*	*				0	93.6	0	-81.4	159.7	140.6	0	0	107.4
2	N	34.2	Very low	32.5	Very low	167 Å²	167	150.5 Å²	150.5	89%	0.893	85%	0.845	S	S	*	*			trans	-87.3	113.2	-171.4	-73.9	-10.9	0	0	0	109.4	P4	N2-P4 WeakPolarHBondContact O-CD 3.47Å
3	N	31.7	Very low	32.7	Very low	156 Å²	156	148.7 Å²	148.7	83%	0.834	84%	0.844	S	S	*	*			trans	-92.7	111.2	175.6	-152.6	3.1	0	0	0	108.5
4	P	39.5	Very low	32.8	Very low	113 Å²	113	144.5 Å²	144.5	73%	0.734	84%	0.837	S	S	*	*			trans	-77.2	129.4	-174.3	29.7	-30.3	0	0	0	110.7	N2 S6	N2-P4 WeakPolarHBondContact O-CD 3.47Å; P4-S6 PolarHBondContact O-N 3.18Å
5	R	34.8	Very low	32.7	Very low	243 Å²	243	144.5 Å²	144.5	92%	0.917	83%	0.833	S	S	*	*			trans	-65.4	109.9	175.8	-73	177.4	174.9	169.3	-1.7	109.7	V7	R5-V7 PolarHBondContact O-N 3.19Å
6	S	33.9	Very low	32.7	Very low	112 Å²	112	145.3 Å²	145.3	78%	0.783	83%	0.826	S	S	*	*	P	Polyproline II helix	trans	-66.4	118.3	169.1	54.5	0	0	0	0	110.3	P4	P4-S6 PolarHBondContact O-N 3.18Å
7	V	31.8	Very low	32.9	Very low	139 Å²	139	140.7 Å²	140.7	84%	0.842	81%	0.805	S	S	*	*	P	Polyproline II helix	trans	-77.2	117.8	172.1	175.7	0	0	0	0	108.2	R5	R5-V7 PolarHBondContact O-N 3.19Å
8	S	29.7	Very low	32.9	Very low	104 Å²	104	139.4 Å²	139.4	73%	0.727	80%	0.795	S	S	*	*	P	Polyproline II helix	trans	-71.7	136.9	176	-14.9	0	0	0	0	110.3
9	P	32.1	Very low	33	Very low	119 Å²	119	138.2 Å²	138.2	77%	0.773	79%	0.785	S	S	*	*	P	Polyproline II helix	trans	-74	142.5	-172.3	-9.9	26.1	0	0	0	112.3	V11	P9-V11 PolarHBondContact O-N 3.4Å
10	L	29.5	Very low	33.2	Very low	172 Å²	172	137.1 Å²	137.1	90%	0.901	78%	0.777	S	S	*	*	P	Polyproline II helix	trans	-54.6	118.2	170.6	-116.9	84.9	0	0	0	110	S12	L10-S12 PolarHBondContact O-N 3.1Å
11	V	30.2	Very low	33.2	Very low	137 Å²	137	137.4 Å²	137.4	83%	0.83	77%	0.771	S	S	*	*			trans	-70.3	109	171.5	174.8	0	0	0	0	108.4	P9	P9-V11 PolarHBondContact O-N 3.4Å
12	S	29.5	Very low	33.2	Very low	104 Å²	104	132.1 Å²	132.1	73%	0.727	75%	0.748	S	S	*	*	P	Polyproline II helix	trans	-65.9	142	166.8	-69.1	0	0	0	0	110.2	L10 A14	L10-S12 PolarHBondContact O-N 3.1Å; S12-A14 PolarHBondContact O-N 3.07Å
13	P	34.8	Very low	33.3	Very low	127 Å²	127	131.4 Å²	131.4	83%	0.825	74%	0.739	S	S	*	*	P	Polyproline II helix	trans	-77.6	117.9	-167.9	26.4	-23.4	0	0	0	111.1
14	A	34	Very low	33.5	Very low	90 Å²	90	133.4 Å²	133.4	74%	0.744	74%	0.735	S	S	*	*	P	Polyproline II helix	trans	-67.9	138.2	176.2	0	0	0	0	0	111.8	S12 H16	S12-A14 PolarHBondContact O-N 3.07Å; A14-H16 PolarHBondContact O-N 3.4Å
15	N	31.8	Very low	33.3	Very low	145 Å²	145	136 Å²	136	78%	0.775	74%	0.738	S	S	*	*	P	Polyproline II helix	trans	-48.2	116.4	-179.2	-78.8	-22.4	0	0	0	113	S17	N15-S17 VanDerWaalsContact C-N 3.33Å
16	H	32.9	Very low	33.4	Very low	156 Å²	156	129 Å²	129	72%	0.722	73%	0.726	S	S	*	*			trans	-90.7	8.6	-178.9	-131.3	-64.6	0	0	0	113.3	A14	A14-H16 PolarHBondContact O-N 3.4Å
17	S	35.7	Very low	33.6	Very low	68 Å²	68	125.6 Å²	125.6	48%	0.476	71%	0.709	S	S	.	*	S	Bend	trans	-77.7	-40.8	-175.8	44.3	0	0	0	0	113.2	N15 L19 L20	N15-S17 VanDerWaalsContact C-N 3.33Å; S17-L19 VanDerWaalsContact C-N 3.3Å; S17-L19 PolarHBondContact O-N 3.24Å; S17-L20 PolarHBondContact O-N 3.15Å
18	D	33.9	Very low	33.9	Very low	118 Å²	118	123.7 Å²	123.7	63%	0.631	70%	0.701	S	S	*	*	H	α-helix	trans	-77.5	-19.3	-166	-58.8	-4.3	0	0	0	113	L20	D18-L20 VanDerWaalsContact C-N 3.32Å; D18-L20 PolarHBondContact O-N 3.19Å
19	L	34.9	Very low	34.3	Very low	115 Å²	115	120.8 Å²	120.8	60%	0.602	69%	0.688	S	S	*	*	H	α-helix	trans	-74.3	-18.8	176.2	-98.9	162.9	0	0	0	113.7	S17	S17-L19 VanDerWaalsContact C-N 3.3Å; S17-L19 PolarHBondContact O-N 3.24Å
20	L	35.7	Very low	34.7	Very low	117 Å²	117	120.8 Å²	120.8	61%	0.613	68%	0.681	S	S	*	*	H	α-helix	trans	-84.6	-22.5	179.3	-85.5	162.6	0	0	0	113.2	S17 D18	S17-L20 PolarHBondContact O-N 3.15Å; D18-L20 VanDerWaalsContact C-N 3.32Å; D18-L20 PolarHBondContact O-N 3.19Å
21	E	33.7	Very low	35	Very low	143 Å²	143	120.6 Å²	120.6	67%	0.668	67%	0.673	S	S	*	*	H	α-helix	trans	-77.8	-43	-178	-149.6	114.2	-140.3	0	0	111.5	Q23 R24	E21-Q23 VanDerWaalsContact C-N 3.33Å; E21-Q23 PolarHBondContact O-N 2.86Å; E21-R24 PolarHBondContact O-N 3.21Å; E21-R24 VanDerWaalsContact O-N 3.14Å
22	N	32	Very low	35.5	Very low	129 Å²	129	117.5 Å²	117.5	69%	0.69	66%	0.658	S	S	*	*	H	α-helix	trans	-70.7	-24.2	-180	-90.6	-18.7	0	0	0	114.1
23	Q	37	Very low	35.9	Very low	152 Å²	152	122 Å²	122	71%	0.71	66%	0.659	S	S	*	*	H	α-helix	trans	-76.4	-20.8	172.8	-81.9	-91.8	-61.9	0	0	113	E21	E21-Q23 VanDerWaalsContact C-N 3.33Å; E21-Q23 PolarHBondContact O-N 2.86Å
24	R	36.5	Very low	35.9	Very low	199 Å²	199	121.4 Å²	121.4	75%	0.751	65%	0.648	S	S	*	*	H	α-helix	trans	-77.7	-30	-180	-80	-175.7	178.4	-171.4	0.9	113.6	E21	E21-R24 PolarHBondContact O-N 3.21Å; E21-R24 VanDerWaalsContact O-N 3.14Å
25	Q	34.1	Very low	36	Very low	168 Å²	168	125 Å²	125	79%	0.785	65%	0.649	S	S	*	*	H	α-helix	trans	-76	-27.2	-178.8	-73.2	-172.7	-3.4	0	0	113.8
26	S	37.9	Very low	36.4	Very low	95 Å²	95	127.2 Å²	127.2	66%	0.664	65%	0.652	S	S	*	*	H	α-helix	trans	-84.4	-14.8	179.6	-164.7	0	0	0	0	114.5
27	G	38.1	Very low	36.6	Very low	41 Å²	41	130.7 Å²	130.7	42%	0.423	66%	0.659	S	S	.	*	H	α-helix	trans	-90.1	-22	-174.1	0	0	0	0	0	115.7	G29	G27-G29 PolarHBondContact O-N 3.46Å
28	S	38.6	Very low	36.4	Very low	98 Å²	98	133.9 Å²	133.9	69%	0.685	67%	0.67	S	S	*	*	H	α-helix	trans	-79.4	-17.6	-172.4	-164	0	0	0	0	114
29	G	38.4	Very low	36.1	Very low	43 Å²	43	131.4 Å²	131.4	44%	0.443	67%	0.671	S	S	.	*	H	α-helix	trans	-75.7	-40.4	-179.8	0	0	0	0	0	113.7	G27 S32	G27-G29 PolarHBondContact O-N 3.46Å; G29-S32 PolarHBondContact O-OG 3.47Å
30	D	39.8	Very low	36	Very low	119 Å²	119	130.7 Å²	130.7	64%	0.636	68%	0.682	S	S	*	*	H	α-helix	trans	-81.1	-29.3	-169.5	-80.8	-21.7	0	0	0	114	S32 R33 L34	D30-S32 PolarHBondContact O-N 3.2Å; D30-R33 PolarHBondContact O-N 3.34Å; D30-L34 PolarHBondContact O-N 3.24Å
31	F	34.9	Very low	35.7	Very low	168 Å²	168	136.7 Å²	136.7	74%	0.737	70%	0.697	S	S	*	*	H	α-helix	trans	-66.6	-37.2	176.1	-97.8	-87.7	0	0	0	112.4	R33 L34 E35	F31-R33 VanDerWaalsContact C-N 3.27Å; F31-R33 PolarHBondContact O-N 2.89Å; F31-L34 PolarHBondContact O-N 3.33Å; F31-E35 PolarHBondContact O-N 3.46Å
32	S	41.8	Very low	35.6	Very low	73 Å²	73	139.5 Å²	139.5	51%	0.51	71%	0.707	S	S	.	*	H	α-helix	trans	-67.2	-25.6	179.1	73.9	0	0	0	0	113.5	G29 D30	G29-S32 PolarHBondContact O-OG 3.47Å; D30-S32 PolarHBondContact O-N 3.2Å
33	R	37.9	Very low	35.3	Very low	198 Å²	198	141.6 Å²	141.6	75%	0.747	72%	0.715	S	S	*	*	H	α-helix	trans	-80.7	-29.6	176.3	-81.3	-175	174.4	-177.5	0.1	113.1	D30 F31	D30-R33 PolarHBondContact O-N 3.34Å; F31-R33 VanDerWaalsContact C-N 3.27Å; F31-R33 PolarHBondContact O-N 2.89Å
34	L	34	Very low	34.8	Very low	115 Å²	115	143.2 Å²	143.2	60%	0.602	72%	0.719	S	S	*	*	H	α-helix	trans	-75.6	-36.9	-179.5	-149.3	80.1	0	0	0	111.8	D30 F31 K36 R37	D30-L34 PolarHBondContact O-N 3.24Å; F31-L34 PolarHBondContact O-N 3.33Å; L34-K36 VanDerWaalsContact C-N 3.32Å; L34-K36 PolarHBondContact O-N 3.11Å; L34-R37 PolarHBondContact O-N 2.98Å; L34-R37 VanDerWaalsContact O-N 3.14Å
35	E	36.3	Very low	34.2	Very low	164 Å²	164	143.1 Å²	143.1	77%	0.766	73%	0.725	S	S	*	*	H	α-helix	trans	-67.6	-31.5	-179.1	-159.4	164.7	-167.5	0	0	112.5	F31 R37 I38	F31-E35 PolarHBondContact O-N 3.46Å; E35-R37 VanDerWaalsContact C-N 3.26Å; E35-R37 PolarHBondContact O-N 3.06Å; E35-I38 PolarHBondContact O-N 3.48Å
36	K	39.8	Very low	33.9	Very low	193 Å²	193	143.5 Å²	143.5	84%	0.839	73%	0.726	S	S	*	*	T	Hydrogen-bonded Turn	trans	-68.4	-16.8	173.5	-92.5	-176.5	177.9	177	0	114.7	L34	L34-K36 VanDerWaalsContact C-N 3.32Å; L34-K36 PolarHBondContact O-N 3.11Å
37	R	38.2	Very low	33.7	Very low	228 Å²	228	144.7 Å²	144.7	86%	0.86	73%	0.734	S	S	*	*	T	Hydrogen-bonded Turn	trans	-93.8	-11.6	179.3	-89.1	-170.6	-176.6	-171.5	2.5	114.7	L34 E35	L34-R37 PolarHBondContact O-N 2.98Å; L34-R37 VanDerWaalsContact O-N 3.14Å; E35-R37 VanDerWaalsContact C-N 3.26Å; E35-R37 PolarHBondContact O-N 3.06Å
38	I	31.3	Very low	33.3	Very low	136 Å²	136	152.4 Å²	152.4	70%	0.697	76%	0.756	S	S	*	*			trans	-105.8	35.3	-176.8	-48.6	179.3	0	0	0	110.9	E35 A40	E35-I38 PolarHBondContact O-N 3.48Å; I38-A40 PolarHBondContact O-N 3.49Å; I38-A40 VanDerWaalsContact O-N 3.1Å
39	G	28.1	Very low	32.8	Very low	65 Å²	65	153.4 Å²	153.4	67%	0.67	76%	0.763	S	S	*	*			trans	-64.1	107	166.6	0	0	0	0	0	111.6
40	A	31	Very low	32.4	Very low	100 Å²	100	160 Å²	160	83%	0.826	79%	0.785	S	S	*	*			trans	51.8	67.4	151.3	0	0	0	0	0	118.3	I38	I38-A40 PolarHBondContact O-N 3.49Å; I38-A40 VanDerWaalsContact O-N 3.1Å
41	R	31	Very low	32	Very low	244 Å²	244	160.4 Å²	160.4	92%	0.921	79%	0.794	S	S	*	*			trans	-98.7	95.2	153.4	-83.2	-175	177	-176.9	-0.4	110.2	M43	R41-M43 PolarHBondContact O-N 3.37Å
42	K	30	Very low	31.8	Very low	202 Å²	202	164.7 Å²	164.7	88%	0.878	81%	0.805	S	S	*	*			trans	-58.9	100.3	166.7	-99.7	178.2	173.5	172.8	0	109.5	K44	K42-K44 PolarHBondContact O-N 2.96Å
43	M	26.5	Very low	31.1	Very low	173 Å²	173	165 Å²	165	85%	0.852	82%	0.819	S	S	*	*			trans	-75.7	108.1	166.4	-95.2	-179.3	174.3	0	0	109.3	R41	R41-M43 PolarHBondContact O-N 3.37Å
44	K	25.9	Very low	30.8	Very low	186 Å²	186	160.6 Å²	160.6	81%	0.809	83%	0.825	S	S	*	*			trans	-89.6	119.2	166.8	-85.4	-177.6	174.2	-178.6	0	108.9	K42	K42-K44 PolarHBondContact O-N 2.96Å
45	F	25.5	Very low	30.8	Very low	197 Å²	197	163.2 Å²	163.2	86%	0.864	84%	0.837	S	S	*	*			trans	-75.6	117.5	173.7	-80	-95.4	0	0	0	110.1
46	H	27.4	Very low	30.5	Very low	176 Å²	176	164.4 Å²	164.4	82%	0.815	84%	0.839	S	S	*	*			trans	-93.6	112.5	168.1	-91.1	-67.9	0	0	0	109.6	K48	H46-K48 PolarHBondContact O-N 2.94Å
47	S	33.3	Very low	29.9	Very low	120 Å²	120	163.5 Å²	163.5	84%	0.839	84%	0.843	S	S	*	*	P	Polyproline II helix	trans	-74	118.3	167.6	50.9	0	0	0	0	109.5
48	K	29.2	Very low	29.5	Very low	203 Å²	203	158.4 Å²	158.4	88%	0.883	83%	0.833	S	S	*	*	P	Polyproline II helix	trans	-89.9	121.6	169.8	-74.7	-175.1	176	-177.8	0	108.8	H46	H46-K48 PolarHBondContact O-N 2.94Å
49	S	28.7	Very low	29.6	Very low	118 Å²	118	161 Å²	161	83%	0.825	84%	0.842	S	S	*	*	P	Polyproline II helix	trans	-72.8	135.7	171.4	44.4	0	0	0	0	110.7
50	M	29.4	Very low	29.7	Very low	182 Å²	182	166.2 Å²	166.2	90%	0.897	85%	0.849	S	S	*	*	P	Polyproline II helix	trans	-73.3	142.3	178.5	-79.1	-179.4	-167.4	0	0	111.9	R52	M50-R52 PolarHBondContact O-N 3.18Å
51	P	31.5	Very low	29.8	Very low	128 Å²	128	164.4 Å²	164.4	83%	0.831	83%	0.834	S	S	*	*	P	Polyproline II helix	trans	-74.8	124.7	176.4	-6.2	23.2	0	0	0	111.3	G53	P51-G53 PolarHBondContact O-N 3.49Å
52	R	31.8	Very low	29.8	Very low	258 Å²	258	157.5 Å²	157.5	97%	0.974	82%	0.823	S	S	*	*	S	Bend	trans	-72.1	104	167.5	-80.4	176.5	164.6	166.8	-5.2	109	M50	M50-R52 PolarHBondContact O-N 3.18Å
53	G	26.5	Very low	29.7	Very low	78 Å²	78	158.7 Å²	158.7	80%	0.804	82%	0.822	S	S	*	*			trans	-179	11.4	176.9	0	0	0	0	0	118.9	P51	P51-G53 PolarHBondContact O-N 3.49Å
54	A	30.7	Very low	30.3	Very low	106 Å²	106	157.4 Å²	157.4	88%	0.876	82%	0.818	S	S	*	*			trans	-127.7	75.7	176.4	0	0	0	0	0	109.9
55	M	33.8	Very low	31.1	Very low	171 Å²	171	158.1 Å²	158.1	84%	0.842	82%	0.822	S	S	*	*			trans	-108.6	-0.2	174.8	-166.6	168.4	178.9	0	0	113.5
56	F	30.1	Very low	32.1	Very low	188 Å²	188	153.9 Å²	153.9	83%	0.825	80%	0.804	S	S	*	*	S	Bend	trans	-137.9	92.7	176.2	-71.5	-84.1	0	0	0	108.5
57	L	27.9	Very low	33.6	Very low	175 Å²	175	147.1 Å²	147.1	92%	0.916	78%	0.775	S	S	*	*	S	Bend	trans	163.8	55.2	152.9	-86.8	-179.9	0	0	0	109.4
58	D	31	Very low	35	Very low	121 Å²	121	148.4 Å²	148.4	65%	0.647	77%	0.765	S	S	*	*			trans	-139.5	32.3	174.9	-140.7	26.8	0	0	0	114.5	A61	D58-A61 WeakPolarHBondContact OD1-CB 3.25Å
59	Q	31.4	Very low	36.8	Very low	190 Å²	190	145.3 Å²	145.3	89%	0.888	75%	0.748	S	S	*	*	S	Bend	trans	-77.7	-10.4	169.3	-160	158.8	-3.8	0	0	112.2
60	E	30.3	Very low	38.8	Very low	175 Å²	175	140.9 Å²	140.9	82%	0.818	71%	0.713	S	S	*	*	S	Bend	trans	-97.6	-22.7	175.1	-72.2	-167.7	154.3	0	0	114.7	S62	E60-S62 VanDerWaalsContact C-N 3.26Å; E60-S62 PolarHBondContact O-N 2.67Å
61	A	33.8	Very low	40.7	Very low	62 Å²	62	133.1 Å²	133.1	51%	0.512	68%	0.675	S	S	.	*	T	Hydrogen-bonded Turn	trans	-79.7	-4.1	174.5	0	0	0	0	0	114.4	D58 R63	D58-A61 WeakPolarHBondContact OD1-CB 3.25Å; A61-R63 PolarHBondContact O-N 3.44Å
62	S	30.4	Very low	42.4	Very low	98 Å²	98	128 Å²	128	69%	0.685	64%	0.641	S	S	*	*	T	Hydrogen-bonded Turn	trans	-73.7	-0.2	171.3	-161	0	0	0	0	113.3	E60 N64	E60-S62 VanDerWaalsContact C-N 3.26Å; E60-S62 PolarHBondContact O-N 2.67Å; S62-N64 PolarHBondContact O-N 3.3Å
63	R	29.5	Very low	44.1	Very low	228 Å²	228	115.8 Å²	115.8	86%	0.86	60%	0.595	S	S	*	*	S	Bend	trans	-73	77.4	166.1	-82.4	-176.4	164	168.9	-1.8	110.4	A61 F65	A61-R63 PolarHBondContact O-N 3.44Å; R63-F65 PolarHBondContact O-N 3.28Å
64	N	38.5	Very low	46.3	Very low	145 Å²	145	116 Å²	116	78%	0.775	57%	0.571	S	S	*	*			trans	24.4	84	154.9	-71	-25.6	0	0	0	113.9	S62 H66	S62-N64 PolarHBondContact O-N 3.3Å; N64-H66 PolarHBondContact O-N 3.17Å
65	F	42.4	Very low	47.9	Very low	202 Å²	202	113.3 Å²	113.3	89%	0.886	54%	0.544	S	S	*	.			trans	-66.9	69.3	161.4	-127.3	-90	0	0	0	108.5	R63 D67	R63-F65 PolarHBondContact O-N 3.28Å; F65-D67 PolarHBondContact O-N 3.06Å
66	H	46.2	Very low	48.9	Very low	107 Å²	107	112 Å²	112	50%	0.495	54%	0.538	S	S	.	.			trans	-72.5	100.2	178	-167.6	-4.6	0	0	0	107	N64 K68 D71 R74	N64-H66 PolarHBondContact O-N 3.17Å; H66-K68 PolarHBondContact O-N 2.9Å; H66-D71 IonicContact CE1-OD1 3.88Å; H66-D71 IonicContact CE1-OD2 3.72Å; H66-D71 IonicContact NE2-OD1 2.73Å; H66-R74 PolarHBondContact NE2-NH2 3.26Å
67	D	58.3	Low	49.9	Very low	35 Å²	35	103.8 Å²	103.8	19%	0.187	50%	0.503	C	S	.	.			trans	-69	101.8	179	-158.4	-27.6	0	0	0	108.7	F65 R69 Y70 K135	F65-D67 PolarHBondContact O-N 3.06Å; D67-R69 PolarHBondContact O-N 3.19Å; D67-Y70 HydrophobicContact CB-CD2 3.92Å; D67-Y70 HydrophobicContact CB-CE2 3.84Å; D67-Y70 WeakPolarHBondContact O-CD2 3.24Å; D67-Y70 PolarHBondContact O-N 2.98Å; D67-K135 IonicContact OD2-NZ 3.46Å; D67-K135 PolarHBondContact OD2-NZ 2.89Å
68	K	63.4	Low	51	Low	146 Å²	146	96.3 Å²	96.3	64%	0.635	47%	0.469	S	S	*	.	G	3₁₀ helix	trans	-59.5	-14.2	-174.2	-69.3	-172.3	175.1	-168.5	0	113.9	H66 Y70 D71	H66-K68 PolarHBondContact O-N 2.9Å; K68-Y70 VanDerWaalsContact C-N 3.26Å; K68-Y70 PolarHBondContact O-N 3.48Å; K68-D71 WeakPolarHBondContact CA-OD2 3.49Å; K68-D71 VanDerWaalsContact O-CB 3.27Å; K68-D71 WeakPolarHBondContact O-CB 3.48Å; K68-D71 PolarHBondContact O-N 3.47Å; K68-D71 VanDerWaalsContact O-N 3.1Å
69	R	67.6	Low	51.9	Low	139 Å²	139	98.2 Å²	98.2	53%	0.525	47%	0.471	S	S	.	.	G	3₁₀ helix	trans	-64.6	-29.7	176.6	-64.4	-171.3	-149.9	-164.3	3.9	112.9	D67 D71 L72 L131	D67-R69 PolarHBondContact O-N 3.19Å; R69-D71 PolarHBondContact O-N 3.2Å; R69-L72 WeakPolarHBondContact O-CB 3.43Å; R69-L72 PolarHBondContact O-N 3.36Å; R69-L131 HydrophobicContact CB-CD2 4.36Å
70	Y	70.6	Confident	52.6	Low	25 Å²	25	94.5 Å²	94.5	10%	0.098	46%	0.457	C	S	.	.	G	3₁₀ helix	trans	-72.4	-21.4	175.7	-58.8	-63	0	0	0	112.4	D67 K68 L72 F73 L131 W137 P138 L141	D67-Y70 HydrophobicContact CB-CD2 3.92Å; D67-Y70 HydrophobicContact CB-CE2 3.84Å; D67-Y70 WeakPolarHBondContact O-CD2 3.24Å; D67-Y70 PolarHBondContact O-N 2.98Å; K68-Y70 VanDerWaalsContact C-N 3.26Å; K68-Y70 PolarHBondContact O-N 3.48Å; Y70-L72 PolarHBondContact O-N 3.17Å; Y70-F73 PolarHBondContact O-N 2.9Å; Y70-F73 VanDerWaalsContact O-N 3.1Å; Y70-L131 HydrophobicContact CD1-CD1 4.47Å; Y70-L131 HydrophobicContact CD1-CD2 3.98Å; Y70-L131 HydrophobicContact CE1-CD1 4.43Å; Y70-L131 HydrophobicContact CE1-CD2 4.13Å; Y70-W137 HydrophobicContact CE1-CB 4.19Å; Y70-W137 AromaticContact CE1-CD1 3.8Å; Y70-W137 AromaticContact CE1-CG 3.93Å; Y70-W137 HydrophobicContact CE1-CG 3.93Å; Y70-P138 HydrophobicContact CD1-CG 4.29Å; Y70-P138 HydrophobicContact CD2-CG 4.32Å; Y70-P138 HydrophobicContact CE1-CG 4.48Å; Y70-P138 HydrophobicContact CG-CG 4.2Å; Y70-L141 HydrophobicContact CD1-CD1 3.81Å; Y70-L141 HydrophobicContact CE1-CD1 4.49Å
71	D	69.7	Low	53.6	Low	18 Å²	18	90 Å²	90	10%	0.096	44%	0.436	C	S	.	.	G	3₁₀ helix	trans	-63.8	-21.3	176.8	-66.3	-43.4	0	0	0	112.3	H66 K68 R69 F73 R74	H66-D71 IonicContact CE1-OD1 3.88Å; H66-D71 IonicContact CE1-OD2 3.72Å; H66-D71 IonicContact NE2-OD1 2.73Å; K68-D71 WeakPolarHBondContact CA-OD2 3.49Å; K68-D71 VanDerWaalsContact O-CB 3.27Å; K68-D71 WeakPolarHBondContact O-CB 3.48Å; K68-D71 PolarHBondContact O-N 3.47Å; K68-D71 VanDerWaalsContact O-N 3.1Å; R69-D71 PolarHBondContact O-N 3.2Å; D71-F73 PolarHBondContact O-N 3.39Å; D71-R74 WeakPolarHBondContact O-CB 3.45Å; D71-R74 PolarHBondContact O-N 2.9Å; D71-R74 IonicContact OD1-CZ 3.55Å; D71-R74 IonicContact OD1-NE 2.71Å; D71-R74 PolarHBondContact OD1-NE 3.46Å; D71-R74 IonicContact OD1-NH2 3.52Å; D71-R74 PolarHBondContact OD1-NH2 3.36Å; D71-R74 IonicContact OD2-NH2 3.49Å
72	L	67.3	Low	54.3	Low	22 Å²	22	92 Å²	92	12%	0.115	43%	0.43	C	S	.	.	G	3₁₀ helix	trans	-59.2	-28.7	173.3	-96.2	123.3	0	0	0	113.6	R69 Y70 D98 H99 I102	R69-L72 WeakPolarHBondContact O-CB 3.43Å; R69-L72 PolarHBondContact O-N 3.36Å; Y70-L72 PolarHBondContact O-N 3.17Å; L72-D98 HydrophobicContact CD1-CB 4.18Å; L72-D98 HydrophobicContact CD2-CB 4.12Å; L72-D98 WeakPolarHBondContact CD2-O 3.28Å; L72-H99 HydrophobicContact CD2-CB 4.36Å; L72-I102 HydrophobicContact CB-CD1 3.84Å; L72-I102 HydrophobicContact CD2-CB 4.05Å; L72-I102 HydrophobicContact CD2-CD1 3.36Å; L72-I102 HydrophobicContact CD2-CG1 3.75Å; L72-I102 HydrophobicContact CG-CD1 4.1Å
73	F	67.2	Low	55.4	Low	0 Å²	0	93.7 Å²	93.7	0%	0	43%	0.427	C	S	.	.	G	3₁₀ helix	trans	-92.5	-11.1	175.4	-68.3	-80	0	0	0	113	Y70 D71 I102 L131 L141 F205 E207 A208 I462	Y70-F73 PolarHBondContact O-N 2.9Å; Y70-F73 VanDerWaalsContact O-N 3.1Å; D71-F73 PolarHBondContact O-N 3.39Å; F73-I102 HydrophobicContact CE1-CG2 4.48Å; F73-I102 HydrophobicContact CE2-CD1 4.18Å; F73-I102 HydrophobicContact CZ-CD1 4.09Å; F73-L131 HydrophobicContact CD2-CD1 4.27Å; F73-L131 HydrophobicContact CE2-CD1 3.66Å; F73-L131 HydrophobicContact CE2-CD2 4.06Å; F73-L131 HydrophobicContact CE2-CG 3.89Å; F73-L131 HydrophobicContact CZ-CD1 4.41Å; F73-L141 HydrophobicContact CB-CD2 4.21Å; F73-L141 HydrophobicContact CG-CD2 4.38Å; F73-F205 HydrophobicContact CB-CD1 3.9Å; F73-F205 WeakPolarHBondContact O-CA 3.43Å; F73-E207 HydrophobicContact CD1-CB 4.22Å; F73-A208 HydrophobicContact CD1-CB 4.05Å; F73-I462 WeakPolarHBondContact CZ-O 3.4Å
74	R	72.1	Confident	56.5	Low	83 Å²	83	87.4 Å²	87.4	31%	0.313	41%	0.41	S	S	.	.			trans	-78.9	129.6	-171.8	-168.7	155	65.3	137.2	-3.7	111.1	H66 D71 S77 L204	H66-R74 PolarHBondContact NE2-NH2 3.26Å; D71-R74 WeakPolarHBondContact O-CB 3.45Å; D71-R74 PolarHBondContact O-N 2.9Å; D71-R74 IonicContact OD1-CZ 3.55Å; D71-R74 IonicContact OD1-NE 2.71Å; D71-R74 PolarHBondContact OD1-NE 3.46Å; D71-R74 IonicContact OD1-NH2 3.52Å; D71-R74 PolarHBondContact OD1-NH2 3.36Å; D71-R74 IonicContact OD2-NH2 3.49Å; R74-S77 PolarHBondContact NE-OG 3.23Å; R74-S77 PolarHBondContact NH2-OG 3.28Å; R74-L204 VanDerWaalsContact CA-O 3.3Å; R74-L204 WeakPolarHBondContact CA-O 3.24Å
75	T	65	Low	57.2	Low	49 Å²	49	81.9 Å²	81.9	30%	0.301	38%	0.382	S	S	.	.	S	Bend	trans	-66	-41.3	-173.7	39.2	0	0	0	0	115.3	I203 L204 F206	T75-I203 WeakPolarHBondContact CB-O 3.49Å; T75-I203 WeakPolarHBondContact CG2-O 3.3Å; T75-I203 PolarHBondContact OG1-O 3.14Å; T75-L204 PolarHBondContact N-O 3.28Å; T75-L204 VanDerWaalsContact N-O 3.15Å; T75-L204 PolarHBondContact OG1-O 3.39Å; T75-F206 HydrophobicContact CG2-CB 3.05Å; T75-F206 HydrophobicContact CG2-CG 4.23Å
76	M	54.3	Low	57.7	Low	145 Å²	145	78.4 Å²	78.4	71%	0.714	37%	0.373	S	S	*	.	S	Bend	trans	-118.3	-27.3	-161.5	-75.6	-112.4	-72.9	0	0	114.4	G78 K79 L80	M76-G78 PolarHBondContact O-N 3.43Å; M76-K79 PolarHBondContact O-N 3.05Å; M76-L80 PolarHBondContact O-N 3.39Å; M76-L80 VanDerWaalsContact O-N 3.17Å
77	S	50.6	Low	57.9	Low	14 Å²	14	80.9 Å²	80.9	10%	0.098	39%	0.389	C	S	.	.	H	α-helix	trans	-71.2	-35.9	-178.2	72.2	0	0	0	0	112	R74 K79 L80 E81	R74-S77 PolarHBondContact NE-OG 3.23Å; R74-S77 PolarHBondContact NH2-OG 3.28Å; S77-K79 PolarHBondContact O-N 3.22Å; S77-L80 PolarHBondContact O-N 3.19Å; S77-E81 WeakPolarHBondContact O-CA 3.28Å; S77-E81 WeakPolarHBondContact O-CB 3.47Å; S77-E81 PolarHBondContact O-N 3.37Å
78	G	51	Low	57.7	Low	19 Å²	19	89.4 Å²	89.4	20%	0.196	42%	0.419	C	S	.	.	H	α-helix	trans	-57.3	-36.9	178.3	0	0	0	0	0	112	M76 R82	M76-G78 PolarHBondContact O-N 3.43Å; G78-R82 WeakPolarHBondContact O-CB 3.4Å; G78-R82 WeakPolarHBondContact O-CD 3.44Å; G78-R82 WeakPolarHBondContact O-CG 3.5Å; G78-R82 PolarHBondContact O-N 3.49Å; G78-R82 VanDerWaalsContact O-N 3.09Å
79	K	49.3	Very low	56.5	Low	161 Å²	161	85.6 Å²	85.6	70%	0.7	42%	0.421	S	S	*	.	H	α-helix	trans	-77.1	-46.8	176.8	-80.3	-175.4	177.8	177.8	0	112.8	M76 S77 R82 Q83	M76-K79 PolarHBondContact O-N 3.05Å; S77-K79 PolarHBondContact O-N 3.22Å; K79-R82 PolarHBondContact O-N 3.38Å; K79-Q83 WeakPolarHBondContact O-CG 3.2Å; K79-Q83 PolarHBondContact O-N 3.05Å
80	L	46.7	Very low	55	Low	111 Å²	111	86.7 Å²	86.7	58%	0.581	43%	0.429	S	S	*	.	H	α-helix	trans	-69	-42.9	-177.5	-161.4	114.2	0	0	0	111.4	M76 S77 Q83 I84	M76-L80 PolarHBondContact O-N 3.39Å; M76-L80 VanDerWaalsContact O-N 3.17Å; S77-L80 PolarHBondContact O-N 3.19Å; L80-Q83 WeakPolarHBondContact O-CB 3.45Å; L80-Q83 PolarHBondContact O-N 3.29Å; L80-I84 HydrophobicContact CD2-CD1 3.84Å; L80-I84 HydrophobicContact CG-CD1 4.41Å; L80-I84 VanDerWaalsContact O-CG1 3.27Å; L80-I84 WeakPolarHBondContact O-CG1 3.18Å; L80-I84 PolarHBondContact O-N 3.5Å
81	E	51	Low	53.5	Low	81 Å²	81	91.2 Å²	91.2	38%	0.379	46%	0.462	S	S	.	.	H	α-helix	trans	-68.9	-33.2	175.5	-155.3	175.9	-176.1	0	0	111.1	S77 I84 S85	S77-E81 WeakPolarHBondContact O-CA 3.28Å; S77-E81 WeakPolarHBondContact O-CB 3.47Å; S77-E81 PolarHBondContact O-N 3.37Å; E81-I84 PolarHBondContact O-N 3.26Å; E81-S85 VanDerWaalsContact O-CB 3.23Å; E81-S85 WeakPolarHBondContact O-CB 3.23Å; E81-S85 PolarHBondContact O-N 3.42Å; E81-S85 PolarHBondContact O-OG 3.5Å; E81-S85 VanDerWaalsContact O-OG 3.14Å
82	R	49.4	Very low	52	Low	105 Å²	105	93.4 Å²	93.4	40%	0.396	48%	0.476	S	S	.	.	H	α-helix	trans	-63.5	-41.1	167.8	-84.9	172.4	175.8	170.1	0	112.6	G78 K79 I84 S85 N86	G78-R82 WeakPolarHBondContact O-CB 3.4Å; G78-R82 WeakPolarHBondContact O-CD 3.44Å; G78-R82 WeakPolarHBondContact O-CG 3.5Å; G78-R82 PolarHBondContact O-N 3.49Å; G78-R82 VanDerWaalsContact O-N 3.09Å; K79-R82 PolarHBondContact O-N 3.38Å; R82-I84 VanDerWaalsContact C-N 3.33Å; R82-S85 WeakPolarHBondContact CA-OG 3.21Å; R82-S85 PolarHBondContact O-N 3.14Å; R82-S85 PolarHBondContact O-OG 3.32Å; R82-N86 WeakPolarHBondContact O-CB 3.04Å; R82-N86 PolarHBondContact O-N 2.84Å; R82-N86 PolarHBondContact O-OD1 3.36Å
83	Q	53.3	Low	50.5	Low	132 Å²	132	100.2 Å²	100.2	62%	0.617	51%	0.507	S	S	*	.	H	α-helix	trans	-64	-41.2	175.3	-76.2	-179.3	-49.6	0	0	110.9	K79 L80 L87	K79-Q83 WeakPolarHBondContact O-CG 3.2Å; K79-Q83 PolarHBondContact O-N 3.05Å; L80-Q83 WeakPolarHBondContact O-CB 3.45Å; L80-Q83 PolarHBondContact O-N 3.29Å; Q83-L87 PolarHBondContact O-N 3Å
84	I	53	Low	49.3	Very low	97 Å²	97	104.8 Å²	104.8	50%	0.497	54%	0.539	S	S	.	.	H	α-helix	trans	-69.4	-39.1	176.1	-64.1	164.1	0	0	0	111.6	L80 E81 R82 L87 R88	L80-I84 HydrophobicContact CD2-CD1 3.84Å; L80-I84 HydrophobicContact CG-CD1 4.41Å; L80-I84 VanDerWaalsContact O-CG1 3.27Å; L80-I84 WeakPolarHBondContact O-CG1 3.18Å; L80-I84 PolarHBondContact O-N 3.5Å; E81-I84 PolarHBondContact O-N 3.26Å; R82-I84 VanDerWaalsContact C-N 3.33Å; I84-L87 WeakPolarHBondContact O-CB 2.97Å; I84-L87 PolarHBondContact O-N 3.14Å; I84-R88 WeakPolarHBondContact O-CB 3.34Å; I84-R88 PolarHBondContact O-N 2.73Å
85	S	52.9	Low	48	Very low	29 Å²	29	102.4 Å²	102.4	20%	0.203	54%	0.535	C	S	.	.	H	α-helix	trans	-74.4	-34.4	-179.5	69.6	0	0	0	0	112.4	E81 R82 L87 R88 G89	E81-S85 VanDerWaalsContact O-CB 3.23Å; E81-S85 WeakPolarHBondContact O-CB 3.23Å; E81-S85 PolarHBondContact O-N 3.42Å; E81-S85 PolarHBondContact O-OG 3.5Å; E81-S85 VanDerWaalsContact O-OG 3.14Å; R82-S85 WeakPolarHBondContact CA-OG 3.21Å; R82-S85 PolarHBondContact O-N 3.14Å; R82-S85 PolarHBondContact O-OG 3.32Å; S85-L87 VanDerWaalsContact C-N 3.3Å; S85-R88 CarbonylContact O-C 3.59Å; S85-R88 WeakPolarHBondContact O-CA 3.18Å; S85-R88 PolarHBondContact O-N 2.93Å; S85-G89 PolarHBondContact O-N 2.93Å
86	N	52.3	Low	46.9	Very low	128 Å²	128	105.4 Å²	105.4	68%	0.684	55%	0.549	S	S	*	.	H	α-helix	trans	-63.3	-39.4	171.4	-74.2	-3.5	0	0	0	110.6	R82 R88 G89	R82-N86 WeakPolarHBondContact O-CB 3.04Å; R82-N86 PolarHBondContact O-N 2.84Å; R82-N86 PolarHBondContact O-OD1 3.36Å; N86-R88 PolarHBondContact O-N 3.02Å; N86-G89 PolarHBondContact O-N 3.48Å
87	L	50.7	Low	46.5	Very low	160 Å²	160	105.4 Å²	105.4	84%	0.838	55%	0.547	S	S	*	.	H	α-helix	trans	-63.3	-28.5	169.3	-91.7	153	0	0	0	112.8	Q83 I84 S85	Q83-L87 PolarHBondContact O-N 3Å; I84-L87 WeakPolarHBondContact O-CB 2.97Å; I84-L87 PolarHBondContact O-N 3.14Å; S85-L87 VanDerWaalsContact C-N 3.3Å
88	R	53.4	Low	46.4	Very low	213 Å²	213	108.5 Å²	108.5	80%	0.804	56%	0.562	S	S	*	*	T	Hydrogen-bonded Turn	trans	-95.1	3.6	-178.5	-150.8	174.6	-171.1	177.2	4.3	114.6	I84 S85 N86 K90	I84-R88 WeakPolarHBondContact O-CB 3.34Å; I84-R88 PolarHBondContact O-N 2.73Å; S85-R88 CarbonylContact O-C 3.59Å; S85-R88 WeakPolarHBondContact O-CA 3.18Å; S85-R88 PolarHBondContact O-N 2.93Å; N86-R88 PolarHBondContact O-N 3.02Å; R88-K90 VanDerWaalsContact C-N 3.27Å; R88-K90 PolarHBondContact O-N 3.48Å; R88-K90 VanDerWaalsContact O-N 3.14Å
89	G	38.8	Very low	46.3	Very low	66 Å²	66	109.6 Å²	109.6	68%	0.68	56%	0.563	S	S	*	*	T	Hydrogen-bonded Turn	trans	58.1	28.4	171.8	0	0	0	0	0	115.9	S85 N86	S85-G89 PolarHBondContact O-N 2.93Å; N86-G89 PolarHBondContact O-N 3.48Å
90	K	37.1	Very low	46.3	Very low	163 Å²	163	109 Å²	109	71%	0.709	56%	0.56	S	S	*	*			trans	-93.9	121.5	177.9	-121	-179.1	-177.2	-178.8	0	111.1	R88 T92	R88-K90 VanDerWaalsContact C-N 3.27Å; R88-K90 PolarHBondContact O-N 3.48Å; R88-K90 VanDerWaalsContact O-N 3.14Å; K90-T92 PolarHBondContact O-N 3.05Å; K90-T92 PolarHBondContact O-OG1 3.01Å
91	P	37.7	Very low	46.5	Very low	120 Å²	120	106.8 Å²	106.8	78%	0.779	55%	0.546	S	S	*	.			trans	-68.7	122.2	178.8	27.4	-30.6	0	0	0	109.1
92	T	38.9	Very low	46.6	Very low	63 Å²	63	103 Å²	103	39%	0.387	53%	0.529	S	S	.	.			trans	-114.8	73.7	-176.8	-45	0	0	0	0	109.2	K90 S95	K90-T92 PolarHBondContact O-N 3.05Å; K90-T92 PolarHBondContact O-OG1 3.01Å; T92-S95 WeakPolarHBondContact CG2-OG 3.25Å
93	E	36.8	Very low	46.6	Very low	165 Å²	165	101.5 Å²	101.5	77%	0.771	53%	0.532	S	S	*	.			trans	-81.2	-28.6	178.6	-75.7	-178.5	156.5	0	0	112.8	S95	E93-S95 PolarHBondContact O-N 3.39Å
94	S	41.5	Very low	46.6	Very low	97 Å²	97	100.4 Å²	100.4	68%	0.678	53%	0.527	S	S	*	.	H	α-helix	trans	-71.1	-32.9	-177	56.4	0	0	0	0	114.3
95	S	45.1	Very low	46.9	Very low	33 Å²	33	99.8 Å²	99.8	23%	0.231	53%	0.53	C	S	.	.	H	α-helix	trans	-75.4	-26.3	-178.6	72.7	0	0	0	0	113.1	T92 E93 Q97 H99	T92-S95 WeakPolarHBondContact CG2-OG 3.25Å; E93-S95 PolarHBondContact O-N 3.39Å; S95-Q97 PolarHBondContact O-N 3.19Å; S95-H99 VanDerWaalsContact O-CB 3.29Å; S95-H99 WeakPolarHBondContact O-CB 3.29Å; S95-H99 PolarHBondContact O-CD2 3.16Å; S95-H99 PolarHBondContact O-N 3.2Å
96	L	41.9	Very low	47.6	Very low	112 Å²	112	98.8 Å²	98.8	59%	0.586	52%	0.523	S	S	*	.	H	α-helix	trans	-66.8	-37.7	-177.9	-88.4	161.1	0	0	0	112.1	K100	L96-K100 PolarHBondContact O-N 3.14Å
97	Q	45.1	Very low	48.4	Very low	144 Å²	144	96.2 Å²	96.2	67%	0.673	51%	0.512	S	S	*	.	H	α-helix	trans	-74.6	-46.7	-178.6	-155.5	159.3	8.4	0	0	111.3	S95 H99 K100 E101	S95-Q97 PolarHBondContact O-N 3.19Å; Q97-H99 VanDerWaalsContact C-N 3.33Å; Q97-H99 PolarHBondContact O-N 3Å; Q97-K100 WeakPolarHBondContact O-CB 3.4Å; Q97-K100 PolarHBondContact O-N 3.42Å; Q97-E101 PolarHBondContact O-N 3.14Å
98	D	49.2	Very low	49	Very low	79 Å²	79	88.8 Å²	88.8	42%	0.422	47%	0.474	S	S	.	.	H	α-helix	trans	-61.3	-40.2	175.7	-74.9	-10.4	0	0	0	112	L72 K100 E101 I102	L72-D98 HydrophobicContact CD1-CB 4.18Å; L72-D98 HydrophobicContact CD2-CB 4.12Å; L72-D98 WeakPolarHBondContact CD2-O 3.28Å; D98-K100 VanDerWaalsContact C-N 3.27Å; D98-K100 PolarHBondContact O-N 2.72Å; D98-E101 PolarHBondContact O-N 3.34Å; D98-I102 PolarHBondContact O-N 2.87Å
99	H	48.7	Very low	49.8	Very low	43 Å²	43	81.3 Å²	81.3	20%	0.199	45%	0.45	C	S	.	.	H	α-helix	trans	-64.9	-32.9	175.7	-86.4	-64.8	0	0	0	112.2	L72 S95 Q97 I102 T103	L72-H99 HydrophobicContact CD2-CB 4.36Å; S95-H99 VanDerWaalsContact O-CB 3.29Å; S95-H99 WeakPolarHBondContact O-CB 3.29Å; S95-H99 PolarHBondContact O-CD2 3.16Å; S95-H99 PolarHBondContact O-N 3.2Å; Q97-H99 VanDerWaalsContact C-N 3.33Å; Q97-H99 PolarHBondContact O-N 3Å; H99-I102 PolarHBondContact O-N 2.93Å; H99-T103 VanDerWaalsContact O-CB 3.25Å; H99-T103 WeakPolarHBondContact O-CB 3.43Å; H99-T103 PolarHBondContact O-N 2.84Å; H99-T103 PolarHBondContact O-OG1 3.21Å
100	K	48.5	Very low	51.5	Low	147 Å²	147	78.7 Å²	78.7	64%	0.639	42%	0.419	S	S	*	.	H	α-helix	trans	-67.7	-44.4	179.2	-143.9	175.8	-175.3	-178.3	0	110.8	L96 Q97 D98 I102 T103 E104	L96-K100 PolarHBondContact O-N 3.14Å; Q97-K100 WeakPolarHBondContact O-CB 3.4Å; Q97-K100 PolarHBondContact O-N 3.42Å; D98-K100 VanDerWaalsContact C-N 3.27Å; D98-K100 PolarHBondContact O-N 2.72Å; K100-I102 PolarHBondContact O-N 3.07Å; K100-T103 PolarHBondContact O-N 2.62Å; K100-E104 WeakPolarHBondContact O-CG 3.16Å; K100-E104 PolarHBondContact O-N 2.95Å
101	E	51.5	Low	53.2	Low	65 Å²	65	71 Å²	71	30%	0.304	39%	0.386	S	S	.	.	H	α-helix	trans	-59.1	-32.2	174.7	-73	-170.9	-178.1	0	0	112.8	Q97 D98	Q97-E101 PolarHBondContact O-N 3.14Å; D98-E101 PolarHBondContact O-N 3.34Å
102	I	53.3	Low	54.7	Low	3 Å²	3	68.6 Å²	68.6	2%	0.015	36%	0.363	C	S	.	.	H	α-helix	trans	-83.6	-38.2	178.2	-64.8	-160.8	0	0	0	113.4	L72 F73 D98 H99 K100 V130 R211	L72-I102 HydrophobicContact CB-CD1 3.84Å; L72-I102 HydrophobicContact CD2-CB 4.05Å; L72-I102 HydrophobicContact CD2-CD1 3.36Å; L72-I102 HydrophobicContact CD2-CG1 3.75Å; L72-I102 HydrophobicContact CG-CD1 4.1Å; F73-I102 HydrophobicContact CE1-CG2 4.48Å; F73-I102 HydrophobicContact CE2-CD1 4.18Å; F73-I102 HydrophobicContact CZ-CD1 4.09Å; D98-I102 PolarHBondContact O-N 2.87Å; H99-I102 PolarHBondContact O-N 2.93Å; K100-I102 PolarHBondContact O-N 3.07Å; I102-V130 HydrophobicContact CD1-CG1 3.83Å; I102-V130 HydrophobicContact CG1-CG1 4.22Å; I102-R211 VanDerWaalsContact CG2-NH2 3.34Å; I102-R211 PolarHBondContact O-NH2 3Å
103	T	49.9	Very low	56.2	Low	73 Å²	73	68 Å²	68	45%	0.448	36%	0.357	S	S	.	.	H	α-helix	trans	-75.5	-29.6	-174.3	-51.5	0	0	0	0	111.8	H99 K100 S105	H99-T103 VanDerWaalsContact O-CB 3.25Å; H99-T103 WeakPolarHBondContact O-CB 3.43Å; H99-T103 PolarHBondContact O-N 2.84Å; H99-T103 PolarHBondContact O-OG1 3.21Å; K100-T103 PolarHBondContact O-N 2.62Å; T103-S105 PolarHBondContact O-N 3.41Å
104	E	53.3	Low	57.7	Low	109 Å²	109	60.1 Å²	60.1	51%	0.509	32%	0.321	S	S	.	.	S	Bend	trans	-52.2	125.8	174.1	-84.6	-174.5	-177.3	0	0	110.5	K100 L106 A466	K100-E104 WeakPolarHBondContact O-CG 3.16Å; K100-E104 PolarHBondContact O-N 2.95Å; E104-L106 PolarHBondContact O-N 2.93Å; E104-A466 HydrophobicContact CB-CB 4.07Å
105	S	58.9	Low	59.1	Low	83 Å²	83	55.6 Å²	55.6	58%	0.58	29%	0.289	S	S	*	.			trans	-67.8	102.8	-173.7	56.5	0	0	0	0	110.1	T103 T107	T103-S105 PolarHBondContact O-N 3.41Å; S105-T107 PolarHBondContact O-N 3.23Å; S105-T107 VanDerWaalsContact O-N 3.14Å
106	L	67.6	Low	60	Low	9 Å²	9	58 Å²	58	5%	0.047	30%	0.297	C	S	.	.			trans	-54.1	117.1	169.1	-71.1	155.9	0	0	0	109.4	E104 R110 Y111 R211 I464 A466	E104-L106 PolarHBondContact O-N 2.93Å; L106-R110 HydrophobicContact CD2-CB 4.35Å; L106-R110 HydrophobicContact CD2-CG 3.6Å; L106-Y111 HydrophobicContact CB-CE2 3.73Å; L106-R211 HydrophobicContact CD1-CG 4.49Å; L106-I464 HydrophobicContact CD2-CG2 4.41Å; L106-A466 HydrophobicContact CD2-CB 4.34Å
107	T	69.1	Low	60.8	Low	73 Å²	73	54 Å²	54	45%	0.448	28%	0.283	S	S	.	.			trans	-74.9	157.3	174.9	49.7	0	0	0	0	110.5	S105 D109 R110 Y111	S105-T107 PolarHBondContact O-N 3.23Å; S105-T107 VanDerWaalsContact O-N 3.14Å; T107-D109 PolarHBondContact O-N 3.37Å; T107-R110 WeakPolarHBondContact O-CB 3.18Å; T107-R110 PolarHBondContact O-N 3.37Å; T107-Y111 WeakPolarHBondContact O-CD2 3.41Å
108	A	63.8	Low	61.4	Low	5 Å²	5	48.6 Å²	48.6	4%	0.041	26%	0.26	C	S	.	.	H	α-helix	trans	-55.4	-41.6	177.2	0	0	0	0	0	111.8	R110 Y111 F112 R273	A108-R110 VanDerWaalsContact C-N 3.25Å; A108-R110 PolarHBondContact O-N 3.02Å; A108-Y111 WeakPolarHBondContact O-CB 3.4Å; A108-Y111 PolarHBondContact O-N 3.29Å; A108-Y111 VanDerWaalsContact O-N 3.09Å; A108-F112 HydrophobicContact CB-CE2 4.49Å; A108-F112 WeakPolarHBondContact O-CD2 3.5Å; A108-F112 PolarHBondContact O-N 3.19Å; A108-R273 HydrophobicContact CB-CG 4.43Å
109	D	69.1	Low	62	Low	56 Å²	56	45.5 Å²	45.5	30%	0.299	24%	0.243	S	C	.	.	H	α-helix	trans	-56.4	-36.8	175.8	-67.7	-2.3	0	0	0	112.9	T107 Y111 F112 D113 Q272	T107-D109 PolarHBondContact O-N 3.37Å; D109-Y111 VanDerWaalsContact C-N 3.31Å; D109-Y111 PolarHBondContact O-N 3.48Å; D109-F112 PolarHBondContact O-N 2.89Å; D109-D113 WeakPolarHBondContact O-CB 3.43Å; D109-D113 PolarHBondContact O-N 3.06Å; D109-Q272 PolarHBondContact OD1-OE1 3.5Å; D109-Q272 VanDerWaalsContact OD1-OE1 3.14Å; D109-Q272 PolarHBondContact OD2-NE2 3.42Å; D109-Q272 PolarHBondContact OD2-OE1 3.2Å
110	R	75.5	Confident	62.6	Low	11 Å²	11	44 Å²	44	4%	0.042	24%	0.236	C	C	.	.	H	α-helix	trans	-65	-36.5	178.8	-176.3	62.1	-176.4	130.3	-2.3	111.9	L106 T107 A108 D113 A114 E127 S465 E467	L106-R110 HydrophobicContact CD2-CB 4.35Å; L106-R110 HydrophobicContact CD2-CG 3.6Å; T107-R110 WeakPolarHBondContact O-CB 3.18Å; T107-R110 PolarHBondContact O-N 3.37Å; A108-R110 VanDerWaalsContact C-N 3.25Å; A108-R110 PolarHBondContact O-N 3.02Å; R110-D113 PolarHBondContact O-N 3.47Å; R110-A114 VanDerWaalsContact O-CB 3.31Å; R110-A114 WeakPolarHBondContact O-CB 3.46Å; R110-A114 PolarHBondContact O-N 3.03Å; R110-E127 IonicContact CZ-OE1 3.71Å; R110-E127 IonicContact CZ-OE2 3.45Å; R110-E127 VanDerWaalsContact NH1-CD 3.33Å; R110-E127 IonicContact NH1-OE1 3.41Å; R110-E127 PolarHBondContact NH1-OE1 3.49Å; R110-E127 IonicContact NH1-OE2 3.91Å; R110-E127 PolarHBondContact NH1-OE2 2.91Å; R110-E127 IonicContact NH2-OE1 3.06Å; R110-E127 PolarHBondContact NH2-OE1 2.71Å; R110-E127 IonicContact NH2-OE2 2.9Å; R110-E127 PolarHBondContact NH2-OE2 3.46Å; R110-S465 PolarHBondContact NE-O 3.01Å; R110-S465 PolarHBondContact NH2-O 3.49Å; R110-E467 PolarHBondContact NH2-O 3.22Å
111	Y	72.7	Confident	63.4	Low	1 Å²	1	40 Å²	40	0%	0.004	22%	0.22	C	C	.	.	H	α-helix	trans	-65.8	-45.7	174.2	-70	-76.9	0	0	0	111.1	L106 T107 A108 D109 D113 A114 L115 R211 R214 H215 V461 I464	L106-Y111 HydrophobicContact CB-CE2 3.73Å; T107-Y111 WeakPolarHBondContact O-CD2 3.41Å; A108-Y111 WeakPolarHBondContact O-CB 3.4Å; A108-Y111 PolarHBondContact O-N 3.29Å; A108-Y111 VanDerWaalsContact O-N 3.09Å; D109-Y111 VanDerWaalsContact C-N 3.31Å; D109-Y111 PolarHBondContact O-N 3.48Å; Y111-D113 VanDerWaalsContact C-N 3.27Å; Y111-D113 PolarHBondContact O-N 3.17Å; Y111-A114 PolarHBondContact O-N 2.9Å; Y111-L115 HydrophobicContact CD1-CD1 3.81Å; Y111-L115 VanDerWaalsContact O-CB 3.31Å; Y111-L115 WeakPolarHBondContact O-CB 3.31Å; Y111-L115 PolarHBondContact O-N 2.68Å; Y111-R211 PolarHBondContact OH-O 2.89Å; Y111-R214 HydrophobicContact CE2-CB 4.18Å; Y111-H215 AromaticContact CD1-CD2 3.4Å; Y111-H215 VanDerWaalsContact CD1-CD2 3.4Å; Y111-H215 WeakPolarHBondContact CD1-CD2 3.39Å; Y111-H215 AromaticContact CE1-CD2 3.77Å; Y111-H215 AromaticContact CG-CD2 3.85Å; Y111-V461 HydrophobicContact CE1-CG1 4.37Å; Y111-I464 HydrophobicContact CD1-CD1 3.9Å; Y111-I464 HydrophobicContact CE1-CD1 4.18Å
112	F	69.2	Low	63.9	Low	70 Å²	70	40.3 Å²	40.3	31%	0.307	23%	0.226	S	C	.	.	H	α-helix	trans	-62.6	-34.3	174.9	-70.1	-70.5	0	0	0	113	A108 D109 L120 K124 P216 V278	A108-F112 HydrophobicContact CB-CE2 4.49Å; A108-F112 WeakPolarHBondContact O-CD2 3.5Å; A108-F112 PolarHBondContact O-N 3.19Å; D109-F112 PolarHBondContact O-N 2.89Å; F112-L120 HydrophobicContact CD1-CD1 3.73Å; F112-L120 HydrophobicContact CD1-CD2 4.14Å; F112-L120 HydrophobicContact CE1-CD1 3.64Å; F112-L120 HydrophobicContact CG-CD1 4.47Å; F112-L120 HydrophobicContact CZ-CD1 4.31Å; F112-K124 PolarHBondContact O-NZ 3.39Å; F112-P216 HydrophobicContact CE2-CB 4.06Å; F112-P216 HydrophobicContact CE2-CG 3.9Å; F112-P216 HydrophobicContact CZ-CB 4.02Å; F112-P216 HydrophobicContact CZ-CG 3.91Å; F112-V278 HydrophobicContact CE2-CG1 4.28Å; F112-V278 HydrophobicContact CZ-CG1 4.49Å
113	D	69.4	Low	64.6	Low	49 Å²	49	41.8 Å²	41.8	26%	0.262	23%	0.234	S	C	.	.	H	α-helix	trans	-69.1	-44.9	177.3	-89.8	-23	0	0	0	112.1	D109 R110 Y111 K124 Q468	D109-D113 WeakPolarHBondContact O-CB 3.43Å; D109-D113 PolarHBondContact O-N 3.06Å; R110-D113 PolarHBondContact O-N 3.47Å; Y111-D113 VanDerWaalsContact C-N 3.27Å; Y111-D113 PolarHBondContact O-N 3.17Å; D113-K124 WeakPolarHBondContact O-CD 3.34Å; D113-K124 PolarHBondContact O-NZ 3.45Å; D113-Q468 PolarHBondContact OD2-NE2 3.46Å
114	A	67.9	Low	65.6	Low	0 Å²	0	41.6 Å²	41.6	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-86.4	-29.8	-171	0	0	0	0	0	114	R110 Y111 K124 E127 I464	R110-A114 VanDerWaalsContact O-CB 3.31Å; R110-A114 WeakPolarHBondContact O-CB 3.46Å; R110-A114 PolarHBondContact O-N 3.03Å; Y111-A114 PolarHBondContact O-N 2.9Å; A114-K124 PolarHBondContact O-N 3.22Å; A114-E127 HydrophobicContact CB-CG 3.94Å; A114-I464 HydrophobicContact CB-CD1 4.27Å; A114-I464 HydrophobicContact CB-CG2 3.76Å
115	L	71.3	Confident	66.1	Low	2 Å²	2	45.7 Å²	45.7	1%	0.01	25%	0.246	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-109.7	155.8	-173.4	-63.9	153.6	0	0	0	111.5	Y111 L120 T122 L123 K124 V461 I464	Y111-L115 HydrophobicContact CD1-CD1 3.81Å; Y111-L115 VanDerWaalsContact O-CB 3.31Å; Y111-L115 WeakPolarHBondContact O-CB 3.31Å; Y111-L115 PolarHBondContact O-N 2.68Å; L115-L120 HydrophobicContact CB-CB 3.9Å; L115-L120 HydrophobicContact CB-CD2 4.03Å; L115-L120 HydrophobicContact CD1-CB 4.17Å; L115-L120 WeakPolarHBondContact CD1-O 3.49Å; L115-T122 CarbonylContact C-O 3.37Å; L115-T122 VanDerWaalsContact CA-O 3.31Å; L115-T122 WeakPolarHBondContact CA-O 3.48Å; L115-L123 HydrophobicContact CD2-CD1 4.45Å; L115-K124 WeakPolarHBondContact O-CE 3.46Å; L115-K124 PolarHBondContact O-NZ 3.42Å; L115-V461 HydrophobicContact CD1-CG1 4.14Å; L115-V461 HydrophobicContact CD1-CG2 4.33Å; L115-V461 HydrophobicContact CD2-CG2 4.12Å; L115-I464 HydrophobicContact CD1-CD1 3.28Å; L115-I464 HydrophobicContact CD2-CD1 3.85Å; L115-I464 HydrophobicContact CG-CD1 3.51Å
116	Q	63.7	Low	65.9	Low	85 Å²	85	49.2 Å²	49.2	40%	0.397	25%	0.251	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-132.9	172.4	175.3	43	179.9	11.1	0	0	108.9	L120 E121 T122 L123 K124	Q116-L120 WeakPolarHBondContact O-CA 2.98Å; Q116-E121 PolarHBondContact O-N 3.27Å; Q116-T122 WeakPolarHBondContact CG-O 3.4Å; Q116-T122 WeakPolarHBondContact CG-OG1 3.47Å; Q116-T122 PolarHBondContact N-O 2.85Å; Q116-T122 PolarHBondContact O-N 3.4Å; Q116-T122 PolarHBondContact O-OG1 3.37Å; Q116-L123 PolarHBondContact NE2-O 3.26Å; Q116-L123 VanDerWaalsContact NE2-O 3.09Å; Q116-K124 HydrophobicContact CB-CG 4.04Å; Q116-K124 HydrophobicContact CG-CG 3.64Å
117	G	58.2	Low	66.1	Low	28 Å²	28	49.6 Å²	49.6	29%	0.289	25%	0.253	S	S	.	.	T	Hydrogen-bonded Turn	trans	87.4	169.3	-175.3	0	0	0	0	0	114.3	E119 L120	G117-E119 PolarHBondContact O-N 3.23Å; G117-L120 PolarHBondContact O-N 3.09Å
118	P	58.4	Low	65.9	Low	30 Å²	30	54.3 Å²	54.3	20%	0.195	27%	0.267	C	S	.	.	T	Hydrogen-bonded Turn	trans	-66.8	-38.7	-169.6	30.4	-39.7	0	0	0	112.7	L120 I217 E337 L338	P118-L120 VanDerWaalsContact C-N 3.35Å; P118-I217 VanDerWaalsContact O-CD1 3.29Å; P118-I217 WeakPolarHBondContact O-CD1 3.12Å; P118-E337 HydrophobicContact CB-CB 4.25Å; P118-E337 WeakPolarHBondContact CD-OE2 3.5Å; P118-E337 HydrophobicContact CG-CB 3.53Å; P118-L338 HydrophobicContact CB-CB 4.39Å; P118-L338 HydrophobicContact CB-CD2 3.94Å; P118-L338 HydrophobicContact CB-CG 3.69Å
119	E	61	Low	66.1	Low	13 Å²	13	55.2 Å²	55.2	6%	0.061	27%	0.271	C	S	.	.	T	Hydrogen-bonded Turn	trans	-96.1	6.1	179.8	-66.8	-168.8	148	0	0	111.8	G117 E121 H215 A396	G117-E119 PolarHBondContact O-N 3.23Å; E119-E121 HydrophobicContact CB-CG 3.6Å; E119-H215 PolarHBondContact O-CE1 2.94Å; E119-A396 VanDerWaalsContact CD-CB 3.48Å; E119-A396 WeakPolarHBondContact OE1-CB 3.27Å
120	L	61.5	Low	66.1	Low	13 Å²	13	54.2 Å²	54.2	7%	0.068	27%	0.267	C	S	.	.	T	Hydrogen-bonded Turn	trans	50.5	55	-171.1	-67	166	0	0	0	110.9	F112 L115 Q116 G117 P118 P216 I217 V461	F112-L120 HydrophobicContact CD1-CD1 3.73Å; F112-L120 HydrophobicContact CD1-CD2 4.14Å; F112-L120 HydrophobicContact CE1-CD1 3.64Å; F112-L120 HydrophobicContact CG-CD1 4.47Å; F112-L120 HydrophobicContact CZ-CD1 4.31Å; L115-L120 HydrophobicContact CB-CB 3.9Å; L115-L120 HydrophobicContact CB-CD2 4.03Å; L115-L120 HydrophobicContact CD1-CB 4.17Å; L115-L120 WeakPolarHBondContact CD1-O 3.49Å; Q116-L120 WeakPolarHBondContact O-CA 2.98Å; G117-L120 PolarHBondContact O-N 3.09Å; P118-L120 VanDerWaalsContact C-N 3.35Å; L120-P216 HydrophobicContact CD1-CG 3.84Å; L120-I217 HydrophobicContact CB-CD1 4.07Å; L120-I217 HydrophobicContact CD1-CD1 3.63Å; L120-I217 HydrophobicContact CD1-CG1 4.11Å; L120-I217 HydrophobicContact CG-CD1 3.7Å; L120-V461 WeakPolarHBondContact O-CG2 3.35Å
121	E	65.4	Low	66	Low	62 Å²	62	54 Å²	54	29%	0.29	27%	0.266	S	S	.	.			trans	-110.9	-22.8	-176.2	-62.1	-161.9	144.8	0	0	113.7	Q116 E119 R218 V460 V461	Q116-E121 PolarHBondContact O-N 3.27Å; E119-E121 HydrophobicContact CB-CG 3.6Å; E121-R218 IonicContact OE1-CZ 2.7Å; E121-R218 IonicContact OE1-NE 2.85Å; E121-R218 IonicContact OE1-NH2 3.14Å; E121-R218 PolarHBondContact OE1-NH2 2.91Å; E121-V460 WeakPolarHBondContact O-CG2 3.44Å; E121-V461 HydrophobicContact CB-CG2 4.3Å; E121-V461 HydrophobicContact CG-CG2 4.3Å
122	T	61.9	Low	65.7	Low	72 Å²	72	55 Å²	55	44%	0.442	27%	0.273	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-92.2	128.8	-178.7	46.4	0	0	0	0	110.2	L115 Q116	L115-T122 CarbonylContact C-O 3.37Å; L115-T122 VanDerWaalsContact CA-O 3.31Å; L115-T122 WeakPolarHBondContact CA-O 3.48Å; Q116-T122 WeakPolarHBondContact CG-O 3.4Å; Q116-T122 WeakPolarHBondContact CG-OG1 3.47Å; Q116-T122 PolarHBondContact N-O 2.85Å; Q116-T122 PolarHBondContact O-N 3.4Å; Q116-T122 PolarHBondContact O-OG1 3.37Å
123	L	68.9	Low	65.6	Low	34 Å²	34	57.1 Å²	57.1	18%	0.178	28%	0.284	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-69.9	141.1	176.5	-158.2	87.1	0	0	0	109.9	L115 Q116 E127 I129 I464	L115-L123 HydrophobicContact CD2-CD1 4.45Å; Q116-L123 PolarHBondContact NE2-O 3.26Å; Q116-L123 VanDerWaalsContact NE2-O 3.09Å; L123-E127 HydrophobicContact CD1-CB 4.05Å; L123-E127 HydrophobicContact CD2-CB 3.72Å; L123-E127 WeakPolarHBondContact CD2-O 3.27Å; L123-E127 HydrophobicContact CG-CB 3.78Å; L123-I129 HydrophobicContact CD1-CD1 4.37Å; L123-I129 HydrophobicContact CD1-CG1 4.08Å; L123-I129 HydrophobicContact CD2-CD1 3.95Å; L123-I129 HydrophobicContact CD2-CG1 3.6Å; L123-I129 HydrophobicContact CG-CG1 4.43Å; L123-I464 HydrophobicContact CD1-CG1 4.23Å
124	K	71.4	Confident	65.7	Low	68 Å²	68	62.4 Å²	62.4	30%	0.296	31%	0.312	S	S	.	.	P	Polyproline II helix	trans	-73	142.2	167.8	-68.7	-177.1	-169.7	147.7	0	109.8	F112 D113 A114 L115 Q116 K126 E127	F112-K124 PolarHBondContact O-NZ 3.39Å; D113-K124 WeakPolarHBondContact O-CD 3.34Å; D113-K124 PolarHBondContact O-NZ 3.45Å; A114-K124 PolarHBondContact O-N 3.22Å; L115-K124 WeakPolarHBondContact O-CE 3.46Å; L115-K124 PolarHBondContact O-NZ 3.42Å; Q116-K124 HydrophobicContact CB-CG 4.04Å; Q116-K124 HydrophobicContact CG-CG 3.64Å; K124-K126 PolarHBondContact O-N 2.97Å; K124-E127 PolarHBondContact O-N 3.35Å
125	E	62.4	Low	66.2	Low	195 Å²	195	67.2 Å²	67.2	91%	0.911	33%	0.333	S	S	*	.	T	Hydrogen-bonded Turn	trans	-53.6	-22.3	-173.8	-63.1	179.9	173.4	0	0	115.3
126	K	56.3	Low	66.6	Low	158 Å²	158	72.6 Å²	72.6	69%	0.687	37%	0.366	S	S	*	.	T	Hydrogen-bonded Turn	trans	-88.8	-7.4	-176.9	-62.1	-176.2	-179.6	179.1	0	114.1	K124	K124-K126 PolarHBondContact O-N 2.97Å
127	E	70.3	Confident	67.6	Low	17 Å²	17	68.7 Å²	68.7	8%	0.079	35%	0.348	C	S	.	.			trans	-92.6	153.7	-175.5	-70.2	-66.6	169.6	0	0	112.1	R110 A114 L123 K124 P469	R110-E127 IonicContact CZ-OE1 3.71Å; R110-E127 IonicContact CZ-OE2 3.45Å; R110-E127 VanDerWaalsContact NH1-CD 3.33Å; R110-E127 IonicContact NH1-OE1 3.41Å; R110-E127 PolarHBondContact NH1-OE1 3.49Å; R110-E127 IonicContact NH1-OE2 3.91Å; R110-E127 PolarHBondContact NH1-OE2 2.91Å; R110-E127 IonicContact NH2-OE1 3.06Å; R110-E127 PolarHBondContact NH2-OE1 2.71Å; R110-E127 IonicContact NH2-OE2 2.9Å; R110-E127 PolarHBondContact NH2-OE2 3.46Å; A114-E127 HydrophobicContact CB-CG 3.94Å; L123-E127 HydrophobicContact CD1-CB 4.05Å; L123-E127 HydrophobicContact CD2-CB 3.72Å; L123-E127 WeakPolarHBondContact CD2-O 3.27Å; L123-E127 HydrophobicContact CG-CB 3.78Å; K124-E127 PolarHBondContact O-N 3.35Å; E127-P469 WeakPolarHBondContact OE1-CD 3.41Å; E127-P469 WeakPolarHBondContact OE2-CD 3.27Å
128	K	66.4	Low	69.1	Low	171 Å²	171	69.5 Å²	69.5	74%	0.743	35%	0.348	S	S	*	.			trans	-114.8	133.8	174.6	-69.8	-173.2	178.3	-174.7	0	110.3	S465	K128-S465 PolarHBondContact O-OG 2.62Å
129	I	68.3	Low	70.6	Confident	24 Å²	24	72.5 Å²	72.5	12%	0.123	36%	0.358	C	S	.	.	B	Isolated β-bridge	trans	-87.3	141.8	175.9	-52	-172.2	0	0	0	109.4	L123 L131 E133 W137 V460 A463	L123-I129 HydrophobicContact CD1-CD1 4.37Å; L123-I129 HydrophobicContact CD1-CG1 4.08Å; L123-I129 HydrophobicContact CD2-CD1 3.95Å; L123-I129 HydrophobicContact CD2-CG1 3.6Å; L123-I129 HydrophobicContact CG-CG1 4.43Å; I129-L131 HydrophobicContact CG2-CB 4.39Å; I129-E133 HydrophobicContact CB-CG 4.44Å; I129-E133 HydrophobicContact CD1-CG 3.8Å; I129-E133 WeakPolarHBondContact CD1-OE1 3.42Å; I129-E133 HydrophobicContact CG1-CG 4.4Å; I129-E133 VanDerWaalsContact CG1-OE1 3.27Å; I129-E133 WeakPolarHBondContact CG1-OE1 3.38Å; I129-W137 HydrophobicContact CG2-CH2 4.36Å; I129-W137 HydrophobicContact CG2-CZ2 4.32Å; I129-V460 HydrophobicContact CD1-CB 3.71Å; I129-V460 HydrophobicContact CD1-CG1 3.48Å; I129-V460 VanDerWaalsContact CD1-CG1 3.48Å; I129-A463 HydrophobicContact CG2-CB 3.35Å; I129-A463 WeakPolarHBondContact CG2-O 3.36Å
130	V	69	Low	72	Confident	36 Å²	36	73.3 Å²	73.3	22%	0.218	36%	0.362	C	S	.	.	S	Bend	trans	-72.1	-32.5	178.8	-178.3	0	0	0	0	111.6	I102 A463	I102-V130 HydrophobicContact CD1-CG1 3.83Å; I102-V130 HydrophobicContact CG1-CG1 4.22Å; V130-A463 WeakPolarHBondContact CG2-O 3.45Å; V130-A463 PolarHBondContact N-O 3.38Å
131	L	71.6	Confident	73.4	Confident	6 Å²	6	72.7 Å²	72.7	3%	0.031	36%	0.359	C	S	.	.	S	Bend	trans	-91.3	149.9	176.4	-70.7	179.5	0	0	0	111.7	R69 Y70 F73 I129 E133 W137 A463	R69-L131 HydrophobicContact CB-CD2 4.36Å; Y70-L131 HydrophobicContact CD1-CD1 4.47Å; Y70-L131 HydrophobicContact CD1-CD2 3.98Å; Y70-L131 HydrophobicContact CE1-CD1 4.43Å; Y70-L131 HydrophobicContact CE1-CD2 4.13Å; F73-L131 HydrophobicContact CD2-CD1 4.27Å; F73-L131 HydrophobicContact CE2-CD1 3.66Å; F73-L131 HydrophobicContact CE2-CD2 4.06Å; F73-L131 HydrophobicContact CE2-CG 3.89Å; F73-L131 HydrophobicContact CZ-CD1 4.41Å; I129-L131 HydrophobicContact CG2-CB 4.39Å; L131-E133 PolarHBondContact O-N 2.7Å; L131-W137 HydrophobicContact CB-CD2 4.49Å; L131-W137 HydrophobicContact CB-CH2 3.94Å; L131-W137 HydrophobicContact CB-CZ2 3.32Å; L131-W137 HydrophobicContact CD1-CD2 3.81Å; L131-W137 HydrophobicContact CD1-CE3 3.76Å; L131-W137 HydrophobicContact CD1-CH2 3.73Å; L131-W137 HydrophobicContact CD1-CZ2 3.77Å; L131-W137 HydrophobicContact CD1-CZ3 3.71Å; L131-W137 HydrophobicContact CG-CH2 4.44Å; L131-W137 HydrophobicContact CG-CZ2 4.18Å; L131-A463 HydrophobicContact CB-CB 4.03Å; L131-A463 HydrophobicContact CD1-CB 3.93Å; L131-A463 HydrophobicContact CG-CB 3.99Å
132	P	67.7	Low	74.6	Confident	23 Å²	23	72.2 Å²	72.2	15%	0.149	36%	0.355	C	S	.	.			trans	-64.8	126.9	178.7	26.3	-33.1	0	0	0	111.2	W137	P132-W137 PolarHBondContact O-NE1 2.99Å
133	E	67.2	Low	76	Confident	114 Å²	114	69.2 Å²	69.2	53%	0.533	34%	0.336	S	S	.	.	T	Hydrogen-bonded Turn	trans	-72	-32	176.7	-72.7	179.2	-165.3	0	0	112.2	I129 L131 K135	I129-E133 HydrophobicContact CB-CG 4.44Å; I129-E133 HydrophobicContact CD1-CG 3.8Å; I129-E133 WeakPolarHBondContact CD1-OE1 3.42Å; I129-E133 HydrophobicContact CG1-CG 4.4Å; I129-E133 VanDerWaalsContact CG1-OE1 3.27Å; I129-E133 WeakPolarHBondContact CG1-OE1 3.38Å; L131-E133 PolarHBondContact O-N 2.7Å; E133-K135 PolarHBondContact O-N 3Å; E133-K135 VanDerWaalsContact O-N 3.15Å
134	D	71.9	Confident	77.2	Confident	160 Å²	160	68.2 Å²	68.2	86%	0.856	33%	0.331	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.6	-9.8	-172.1	-50.8	-41.3	0	0	0	114.2
135	K	77.8	Confident	78.2	Confident	101 Å²	101	65 Å²	65	44%	0.439	32%	0.317	S	S	.	.	S	Bend	trans	-117.7	142	-176.3	-66.1	-172	-174.3	176.3	0	111.4	D67 E133 W137 N458	D67-K135 IonicContact OD2-NZ 3.46Å; D67-K135 PolarHBondContact OD2-NZ 2.89Å; E133-K135 PolarHBondContact O-N 3Å; E133-K135 VanDerWaalsContact O-N 3.15Å; K135-W137 VanDerWaalsContact O-CD1 3.23Å; K135-W137 PolarHBondContact O-N 3.16Å; K135-N458 PolarHBondContact O-ND2 3.36Å
136	T	80.1	Confident	79.6	Confident	114 Å²	114	56.1 Å²	56.1	70%	0.699	28%	0.276	S	S	*	.	P	Polyproline II helix	trans	-69.7	124.7	168.6	50.6	0	0	0	0	109.9
137	W	83.9	Confident	81.4	Confident	4 Å²	4	48.6 Å²	48.6	2%	0.015	24%	0.244	C	C	.	.	P	Polyproline II helix	trans	-75.9	161	-179.2	-62	-4.2	0	0	0	111.5	Y70 I129 L131 P132 K135 F139 L141 R142 N458 D459 I462 A463	Y70-W137 HydrophobicContact CE1-CB 4.19Å; Y70-W137 AromaticContact CE1-CD1 3.8Å; Y70-W137 AromaticContact CE1-CG 3.93Å; Y70-W137 HydrophobicContact CE1-CG 3.93Å; I129-W137 HydrophobicContact CG2-CH2 4.36Å; I129-W137 HydrophobicContact CG2-CZ2 4.32Å; L131-W137 HydrophobicContact CB-CD2 4.49Å; L131-W137 HydrophobicContact CB-CH2 3.94Å; L131-W137 HydrophobicContact CB-CZ2 3.32Å; L131-W137 HydrophobicContact CD1-CD2 3.81Å; L131-W137 HydrophobicContact CD1-CE3 3.76Å; L131-W137 HydrophobicContact CD1-CH2 3.73Å; L131-W137 HydrophobicContact CD1-CZ2 3.77Å; L131-W137 HydrophobicContact CD1-CZ3 3.71Å; L131-W137 HydrophobicContact CG-CH2 4.44Å; L131-W137 HydrophobicContact CG-CZ2 4.18Å; P132-W137 PolarHBondContact O-NE1 2.99Å; K135-W137 VanDerWaalsContact O-CD1 3.23Å; K135-W137 PolarHBondContact O-N 3.16Å; W137-F139 PolarHBondContact O-N 3.33Å; W137-L141 HydrophobicContact CB-CB 4.48Å; W137-L141 HydrophobicContact CE3-CB 4.47Å; W137-R142 HydrophobicContact CB-CG 4.02Å; W137-R142 PolarHBondContact O-NE 3.31Å; W137-N458 HydrophobicContact CD2-CB 4.06Å; W137-N458 HydrophobicContact CE3-CB 4.29Å; W137-N458 HydrophobicContact CG-CB 4.44Å; W137-N458 HydrophobicContact CZ2-CB 4.31Å; W137-N458 PolarHBondContact N-OD1 2.87Å; W137-D459 VanDerWaalsContact CZ3-O 3.28Å; W137-D459 WeakPolarHBondContact CZ3-O 3.36Å; W137-I462 HydrophobicContact CE3-CD1 4.39Å; W137-I462 HydrophobicContact CZ3-CD1 4.06Å; W137-I462 HydrophobicContact CZ3-CG1 4.02Å; W137-A463 HydrophobicContact CH2-CB 3.42Å; W137-A463 VanDerWaalsContact CH2-CB 3.42Å; W137-A463 HydrophobicContact CZ2-CB 4.19Å; W137-A463 HydrophobicContact CZ3-CB 4.06Å
138	P	88.7	Confident	82.6	Confident	45 Å²	45	48.3 Å²	48.3	29%	0.292	24%	0.242	S	C	.	.	P	Polyproline II helix	trans	-46.6	135.8	167.9	-28.1	33.4	0	0	0	111.7	Y70 L140 L141 R142	Y70-P138 HydrophobicContact CD1-CG 4.29Å; Y70-P138 HydrophobicContact CD2-CG 4.32Å; Y70-P138 HydrophobicContact CE1-CG 4.48Å; Y70-P138 HydrophobicContact CG-CG 4.2Å; P138-L140 PolarHBondContact O-N 3.25Å; P138-L140 VanDerWaalsContact O-N 3.15Å; P138-L141 HydrophobicContact CB-CD1 4.45Å; P138-L141 HydrophobicContact CG-CD1 4.21Å; P138-L141 WeakPolarHBondContact O-CB 3.49Å; P138-L141 PolarHBondContact O-N 3.27Å; P138-R142 PolarHBondContact O-N 2.86Å
139	F	90.5	Very high	83.9	Confident	92 Å²	92	40.5 Å²	40.5	40%	0.404	21%	0.21	S	C	.	.	H	α-helix	trans	-52.6	-40.7	-174.2	173.1	-107.6	0	0	0	113.4	W137 L141 R142 F143 T197 F456	W137-F139 PolarHBondContact O-N 3.33Å; F139-L141 VanDerWaalsContact C-N 3.27Å; F139-L141 PolarHBondContact O-N 3.4Å; F139-R142 CarbonylContact O-C 3.26Å; F139-R142 WeakPolarHBondContact O-CA 3.33Å; F139-R142 WeakPolarHBondContact O-CB 2.95Å; F139-R142 PolarHBondContact O-N 2.89Å; F139-F143 HydrophobicContact CE1-CD2 4.22Å; F139-F143 HydrophobicContact CE2-CD2 4.33Å; F139-F143 HydrophobicContact CZ-CB 4.48Å; F139-F143 AromaticContact CZ-CD2 3.67Å; F139-F143 HydrophobicContact CZ-CD2 3.67Å; F139-F143 HydrophobicContact CZ-CE2 4.33Å; F139-F143 HydrophobicContact CZ-CG 4.41Å; F139-F143 PolarHBondContact O-N 3.33Å; F139-T197 HydrophobicContact CD1-CG2 4.49Å; F139-T197 HydrophobicContact CE1-CG2 3.68Å; F139-T197 HydrophobicContact CZ-CG2 4.44Å; F139-F456 HydrophobicContact CE2-CB 4.31Å; F139-F456 AromaticContact CE2-CD2 3.61Å; F139-F456 HydrophobicContact CE2-CD2 3.61Å; F139-F456 HydrophobicContact CE2-CE2 4.12Å; F139-F456 HydrophobicContact CE2-CG 4.03Å; F139-F456 HydrophobicContact CZ-CD2 4.27Å; F139-F456 HydrophobicContact CZ-CE2 4.34Å
140	L	90.9	Very high	85.1	Confident	30 Å²	30	40.2 Å²	40.2	16%	0.157	21%	0.208	C	C	.	.	H	α-helix	trans	-62.1	-31.6	178.9	-64.1	178.2	0	0	0	113.3	P138 R142 T197 F200 K201 L204 F205	P138-L140 PolarHBondContact O-N 3.25Å; P138-L140 VanDerWaalsContact O-N 3.15Å; L140-R142 VanDerWaalsContact C-N 3.28Å; L140-T197 HydrophobicContact CD2-CG2 4.01Å; L140-T197 WeakPolarHBondContact CD2-O 3.47Å; L140-F200 HydrophobicContact CD1-CB 4.09Å; L140-F200 HydrophobicContact CD2-CB 4.17Å; L140-K201 HydrophobicContact CB-CB 4.32Å; L140-K201 HydrophobicContact CD2-CB 4.46Å; L140-K201 WeakPolarHBondContact O-CD 3.4Å; L140-K201 VanDerWaalsContact O-CE 3.24Å; L140-K201 WeakPolarHBondContact O-CE 3.45Å; L140-K201 VanDerWaalsContact O-CG 3.31Å; L140-K201 WeakPolarHBondContact O-CG 3.36Å; L140-L204 HydrophobicContact CD1-CD1 3.66Å; L140-F205 HydrophobicContact CB-CD2 3.89Å; L140-F205 HydrophobicContact CB-CE2 3.95Å; L140-F205 HydrophobicContact CD1-CD2 4.27Å; L140-F205 HydrophobicContact CD1-CE2 4.09Å
141	L	89.9	Confident	86.4	Confident	0 Å²	0	38.5 Å²	38.5	0%	0	20%	0.198	C	C	.	.	H	α-helix	trans	-74.1	-23.2	174.2	-72.1	174.2	0	0	0	111.9	Y70 F73 W137 P138 F139 F205 A208 D459 I462	Y70-L141 HydrophobicContact CD1-CD1 3.81Å; Y70-L141 HydrophobicContact CE1-CD1 4.49Å; F73-L141 HydrophobicContact CB-CD2 4.21Å; F73-L141 HydrophobicContact CG-CD2 4.38Å; W137-L141 HydrophobicContact CB-CB 4.48Å; W137-L141 HydrophobicContact CE3-CB 4.47Å; P138-L141 HydrophobicContact CB-CD1 4.45Å; P138-L141 HydrophobicContact CG-CD1 4.21Å; P138-L141 WeakPolarHBondContact O-CB 3.49Å; P138-L141 PolarHBondContact O-N 3.27Å; F139-L141 VanDerWaalsContact C-N 3.27Å; F139-L141 PolarHBondContact O-N 3.4Å; L141-F205 HydrophobicContact CD1-CD1 4.34Å; L141-F205 HydrophobicContact CD1-CE1 4.13Å; L141-F205 HydrophobicContact CD1-CZ 4.48Å; L141-F205 HydrophobicContact CD2-CB 3.88Å; L141-F205 HydrophobicContact CD2-CD1 3.77Å; L141-F205 HydrophobicContact CD2-CD2 4.33Å; L141-F205 HydrophobicContact CD2-CE1 4.37Å; L141-F205 HydrophobicContact CD2-CG 3.74Å; L141-F205 HydrophobicContact CG-CD1 4.11Å; L141-F205 HydrophobicContact CG-CD2 4.33Å; L141-F205 HydrophobicContact CG-CE1 4.23Å; L141-F205 HydrophobicContact CG-CE2 4.45Å; L141-F205 HydrophobicContact CG-CG 4.16Å; L141-F205 HydrophobicContact CG-CZ 4.39Å; L141-A208 HydrophobicContact CD2-CB 3.74Å; L141-D459 WeakPolarHBondContact O-CB 3.46Å; L141-I462 HydrophobicContact CB-CD1 4.12Å; L141-I462 HydrophobicContact CD2-CD1 3.99Å; L141-I462 VanDerWaalsContact O-CD1 3.25Å; L141-I462 WeakPolarHBondContact O-CD1 3.48Å
142	R	90.7	Very high	87.6	Confident	53 Å²	53	38.6 Å²	38.6	20%	0.2	20%	0.199	C	C	.	.	H	α-helix	trans	-89.7	-11.6	178.5	-61.1	-171.2	-76	142	-6.3	114.1	W137 P138 F139 L140 P144 F456 P457 N458	W137-R142 HydrophobicContact CB-CG 4.02Å; W137-R142 PolarHBondContact O-NE 3.31Å; P138-R142 PolarHBondContact O-N 2.86Å; F139-R142 CarbonylContact O-C 3.26Å; F139-R142 WeakPolarHBondContact O-CA 3.33Å; F139-R142 WeakPolarHBondContact O-CB 2.95Å; F139-R142 PolarHBondContact O-N 2.89Å; L140-R142 VanDerWaalsContact C-N 3.28Å; R142-P144 WeakPolarHBondContact O-CD 3.47Å; R142-F456 HydrophobicContact CB-CB 4.23Å; R142-F456 WeakPolarHBondContact CD-O 3.45Å; R142-F456 PolarHBondContact NH1-O 3.39Å; R142-P457 WeakPolarHBondContact CB-O 3.18Å; R142-P457 WeakPolarHBondContact CG-O 3.45Å; R142-N458 WeakPolarHBondContact CD-OD1 3.36Å
143	F	92.8	Very high	88.9	Confident	9 Å²	9	37.5 Å²	37.5	4%	0.039	19%	0.192	C	C	.	.			trans	-90.7	102.4	-175.1	-170.2	-96.6	0	0	0	110.6	F139 V194 T197 Y198 K201 F456	F139-F143 HydrophobicContact CE1-CD2 4.22Å; F139-F143 HydrophobicContact CE2-CD2 4.33Å; F139-F143 HydrophobicContact CZ-CB 4.48Å; F139-F143 AromaticContact CZ-CD2 3.67Å; F139-F143 HydrophobicContact CZ-CD2 3.67Å; F139-F143 HydrophobicContact CZ-CE2 4.33Å; F139-F143 HydrophobicContact CZ-CG 4.41Å; F139-F143 PolarHBondContact O-N 3.33Å; F143-V194 HydrophobicContact CE1-CG1 4.12Å; F143-V194 HydrophobicContact CZ-CB 4.39Å; F143-V194 HydrophobicContact CZ-CG1 3.97Å; F143-V194 HydrophobicContact CZ-CG2 4.28Å; F143-T197 HydrophobicContact CB-CG2 4.46Å; F143-T197 HydrophobicContact CD1-CG2 3.76Å; F143-T197 HydrophobicContact CD2-CG2 4.08Å; F143-T197 HydrophobicContact CE1-CG2 3.93Å; F143-T197 HydrophobicContact CE2-CG2 4.22Å; F143-T197 HydrophobicContact CG-CG2 3.83Å; F143-T197 HydrophobicContact CZ-CG2 4.15Å; F143-Y198 HydrophobicContact CD1-CD2 4.21Å; F143-Y198 HydrophobicContact CE1-CD2 4.45Å; F143-K201 WeakPolarHBondContact O-CD 3.37Å; F143-K201 PolarHBondContact O-NZ 3.17Å; F143-F456 HydrophobicContact CD2-CD1 4.02Å; F143-F456 AromaticContact CD2-CE1 3.52Å; F143-F456 HydrophobicContact CD2-CE1 3.52Å; F143-F456 HydrophobicContact CD2-CE2 4.21Å; F143-F456 AromaticContact CD2-CZ 3.63Å; F143-F456 HydrophobicContact CD2-CZ 3.63Å; F143-F456 AromaticContact CE2-CE1 3.76Å; F143-F456 HydrophobicContact CE2-CE1 3.76Å; F143-F456 HydrophobicContact CE2-CE2 4.28Å; F143-F456 AromaticContact CE2-CZ 3.52Å; F143-F456 HydrophobicContact CE2-CZ 3.52Å; F143-F456 HydrophobicContact CG-CE1 4.49Å
144	P	92.9	Very high	90.2	Very high	13 Å²	13	32.5 Å²	32.5	8%	0.084	17%	0.169	C	C	.	.			trans	-82.4	157.3	-172.5	35	-37.6	0	0	0	112.1	R142 T146 S147 E212 L395	R142-P144 WeakPolarHBondContact O-CD 3.47Å; P144-T146 WeakPolarHBondContact CB-OG1 3.27Å; P144-T146 VanDerWaalsContact CG-OG1 3.24Å; P144-T146 WeakPolarHBondContact CG-OG1 3.48Å; P144-T146 PolarHBondContact O-N 3.36Å; P144-S147 WeakPolarHBondContact CD-OG 3.19Å; P144-S147 VanDerWaalsContact O-CB 3.24Å; P144-S147 WeakPolarHBondContact O-CB 3.24Å; P144-S147 PolarHBondContact O-N 3.48Å; P144-S147 VanDerWaalsContact O-N 3.11Å; P144-S147 PolarHBondContact O-OG 2.93Å; P144-E212 WeakPolarHBondContact CA-OE1 3.39Å; P144-L395 HydrophobicContact CG-CD2 4.05Å
145	I	93.7	Very high	91.4	Very high	1 Å²	1	25 Å²	25	1%	0.005	13%	0.129	C	C	.	.	G	3₁₀ helix	trans	-58.6	-25.5	171.4	-173.2	57.4	0	0	0	112.9	S147 Y148 Y198 E212 R218 F221 F222 P225	I145-S147 PolarHBondContact O-N 3.27Å; I145-S147 VanDerWaalsContact O-N 3.13Å; I145-Y148 HydrophobicContact CD1-CD2 3.77Å; I145-Y148 HydrophobicContact CD1-CE2 3.92Å; I145-Y148 PolarHBondContact O-N 3.17Å; I145-Y198 HydrophobicContact CB-CE2 3.82Å; I145-Y198 HydrophobicContact CD1-CD1 4.21Å; I145-Y198 HydrophobicContact CD1-CD2 4.4Å; I145-Y198 HydrophobicContact CD1-CE1 3.75Å; I145-Y198 HydrophobicContact CD1-CE2 3.97Å; I145-Y198 HydrophobicContact CG1-CE2 4.45Å; I145-E212 PolarHBondContact N-OE1 3.36Å; I145-R218 HydrophobicContact CG2-CB 3.95Å; I145-F221 HydrophobicContact CG1-CB 3.94Å; I145-F221 HydrophobicContact CG2-CB 4.01Å; I145-F222 HydrophobicContact CG1-CD2 4.23Å; I145-F222 HydrophobicContact CG1-CE2 4.28Å; I145-F222 HydrophobicContact CG1-CG 4.45Å; I145-F222 HydrophobicContact CG2-CE2 4.27Å; I145-P225 HydrophobicContact CD1-CG 4.29Å
146	T	91.7	Very high	92.3	Very high	8 Å²	8	20.4 Å²	20.4	5%	0.049	11%	0.109	C	C	.	.	G	3₁₀ helix	trans	-62.8	-17.9	177.2	56.9	0	0	0	0	113	P144 Y148 G149 R218 F221	P144-T146 WeakPolarHBondContact CB-OG1 3.27Å; P144-T146 VanDerWaalsContact CG-OG1 3.24Å; P144-T146 WeakPolarHBondContact CG-OG1 3.48Å; P144-T146 PolarHBondContact O-N 3.36Å; T146-Y148 PolarHBondContact O-N 3.38Å; T146-Y148 VanDerWaalsContact O-N 3.12Å; T146-G149 PolarHBondContact O-N 3.4Å; T146-R218 HydrophobicContact CG2-CG 4.2Å; T146-F221 HydrophobicContact CG2-CD1 4.2Å; T146-F221 HydrophobicContact CG2-CD2 3.77Å; T146-F221 HydrophobicContact CG2-CE1 4.23Å; T146-F221 HydrophobicContact CG2-CE2 3.8Å; T146-F221 HydrophobicContact CG2-CG 3.95Å; T146-F221 HydrophobicContact CG2-CZ 4.03Å
147	S	93.4	Very high	93	Very high	0 Å²	0	15.1 Å²	15.1	0%	0	8%	0.077	C	C	.	.	G	3₁₀ helix	trans	-57.7	-24.5	174.9	-52.4	0	0	0	0	114.1	P144 I145 G149 M150 L395	P144-S147 WeakPolarHBondContact CD-OG 3.19Å; P144-S147 VanDerWaalsContact O-CB 3.24Å; P144-S147 WeakPolarHBondContact O-CB 3.24Å; P144-S147 PolarHBondContact O-N 3.48Å; P144-S147 VanDerWaalsContact O-N 3.11Å; P144-S147 PolarHBondContact O-OG 2.93Å; I145-S147 PolarHBondContact O-N 3.27Å; I145-S147 VanDerWaalsContact O-N 3.13Å; S147-G149 PolarHBondContact O-N 3.09Å; S147-G149 VanDerWaalsContact O-N 3.16Å; S147-M150 WeakPolarHBondContact O-CB 3.46Å; S147-M150 WeakPolarHBondContact O-CE 3.34Å; S147-M150 WeakPolarHBondContact O-CG 3.34Å; S147-M150 PolarHBondContact O-N 2.74Å; S147-M150 VanDerWaalsContact O-N 3.09Å; S147-L395 WeakPolarHBondContact OG-CD2 3.45Å
148	Y	95.2	Very high	93.6	Very high	10 Å²	10	15 Å²	15	4%	0.039	8%	0.077	C	C	.	.	H	α-helix	trans	-63.8	-14.9	172.2	-83	-90.8	0	0	0	113.4	I145 T146 M150 C151 L152 L191 V194 S195 Y198 A224 P225	I145-Y148 HydrophobicContact CD1-CD2 3.77Å; I145-Y148 HydrophobicContact CD1-CE2 3.92Å; I145-Y148 PolarHBondContact O-N 3.17Å; T146-Y148 PolarHBondContact O-N 3.38Å; T146-Y148 VanDerWaalsContact O-N 3.12Å; Y148-M150 PolarHBondContact O-N 3.18Å; Y148-C151 HydrophobicContact CD1-CB 4.36Å; Y148-C151 WeakPolarHBondContact O-CA 3.38Å; Y148-C151 WeakPolarHBondContact O-CB 3.32Å; Y148-C151 PolarHBondContact O-N 3.36Å; Y148-L152 PolarHBondContact O-N 3.1Å; Y148-L191 HydrophobicContact CD1-CD1 4.13Å; Y148-L191 HydrophobicContact CE1-CD1 3.75Å; Y148-V194 HydrophobicContact CD1-CG1 4.05Å; Y148-V194 HydrophobicContact CD2-CG1 3.75Å; Y148-V194 HydrophobicContact CE1-CG1 3.98Å; Y148-V194 HydrophobicContact CE2-CG1 3.7Å; Y148-V194 HydrophobicContact CG-CG1 3.95Å; Y148-S195 WeakPolarHBondContact OH-CA 3.19Å; Y148-S195 WeakPolarHBondContact OH-CB 3.3Å; Y148-S195 PolarHBondContact OH-OG 2.82Å; Y148-Y198 HydrophobicContact CE2-CD1 4.47Å; Y148-Y198 HydrophobicContact CE2-CG 4.17Å; Y148-A224 VanDerWaalsContact CB-CB 3.48Å; Y148-A224 HydrophobicContact CG-CB 4.29Å; Y148-P225 HydrophobicContact CD1-CB 4.03Å; Y148-P225 HydrophobicContact CD1-CG 3.95Å; Y148-P225 HydrophobicContact CD2-CG 4.02Å; Y148-P225 HydrophobicContact CE1-CB 3.55Å; Y148-P225 HydrophobicContact CE1-CG 3.71Å; Y148-P225 HydrophobicContact CE2-CB 4.44Å; Y148-P225 HydrophobicContact CE2-CG 3.77Å; Y148-P225 HydrophobicContact CG-CG 4.08Å
149	G	93.1	Very high	93.9	Very high	8 Å²	8	13.8 Å²	13.8	8%	0.082	7%	0.067	C	C	.	.	H	α-helix	trans	-52.9	-34.8	168.3	0	0	0	0	0	112.5	T146 S147 L152 G153	T146-G149 PolarHBondContact O-N 3.4Å; S147-G149 PolarHBondContact O-N 3.09Å; S147-G149 VanDerWaalsContact O-N 3.16Å; G149-L152 PolarHBondContact O-N 3.27Å; G149-G153 PolarHBondContact O-N 3.42Å
150	M	94.5	Very high	94.2	Very high	17 Å²	17	9.4 Å²	9.4	8%	0.084	5%	0.048	C	C	.	.	H	α-helix	trans	-61.9	-44.6	173.3	-56.6	-172.1	-82.5	0	0	111.9	S147 Y148 G153 V154 L190 V194 L395 W398 T445	S147-M150 WeakPolarHBondContact O-CB 3.46Å; S147-M150 WeakPolarHBondContact O-CE 3.34Å; S147-M150 WeakPolarHBondContact O-CG 3.34Å; S147-M150 PolarHBondContact O-N 2.74Å; S147-M150 VanDerWaalsContact O-N 3.09Å; Y148-M150 PolarHBondContact O-N 3.18Å; M150-G153 PolarHBondContact O-N 3.22Å; M150-V154 WeakPolarHBondContact O-CG2 3.43Å; M150-V154 PolarHBondContact O-N 2.98Å; M150-L190 HydrophobicContact CB-CD2 4.07Å; M150-V194 HydrophobicContact CE-CG2 4.27Å; M150-L395 HydrophobicContact CE-CD1 4.19Å; M150-L395 HydrophobicContact CG-CD1 4Å; M150-L395 HydrophobicContact SD-CD1 3.87Å; M150-W398 HydrophobicContact CB-CD2 4.1Å; M150-W398 HydrophobicContact CB-CE3 4.43Å; M150-W398 HydrophobicContact CB-CG 4.46Å; M150-W398 HydrophobicContact CB-CZ2 4.34Å; M150-W398 HydrophobicContact CG-CD2 3.83Å; M150-W398 HydrophobicContact CG-CG 3.85Å; M150-W398 HydrophobicContact CG-CZ2 4.15Å; M150-T445 HydrophobicContact SD-CG2 4.2Å
151	C	96.7	Very high	94.4	Very high	0 Å²	0	10 Å²	10	0%	0	5%	0.048	C	C	.	.	H	α-helix	trans	-64.6	-43	179.5	-59.7	0	0	0	0	110.9	Y148 S155 L191 S228	Y148-C151 HydrophobicContact CD1-CB 4.36Å; Y148-C151 WeakPolarHBondContact O-CA 3.38Å; Y148-C151 WeakPolarHBondContact O-CB 3.32Å; Y148-C151 PolarHBondContact O-N 3.36Å; C151-S155 WeakPolarHBondContact O-CB 3.42Å; C151-S155 PolarHBondContact O-N 3.04Å; C151-S155 PolarHBondContact O-OG 3.09Å; C151-L191 HydrophobicContact CB-CD1 4.15Å; C151-S228 WeakPolarHBondContact CB-OG 3.19Å
152	L	95.3	Very high	94.6	Very high	9 Å²	9	11.7 Å²	11.7	5%	0.047	6%	0.056	C	C	.	.	H	α-helix	trans	-60.5	-45.8	176.4	-65.4	175.4	0	0	0	111.7	Y148 G149 S155 S156 A224 I227 S228 F231 L285	Y148-L152 PolarHBondContact O-N 3.1Å; G149-L152 PolarHBondContact O-N 3.27Å; L152-S155 PolarHBondContact O-OG 3.39Å; L152-S156 VanDerWaalsContact O-CB 3.26Å; L152-S156 WeakPolarHBondContact O-CB 3.4Å; L152-S156 PolarHBondContact O-N 3.1Å; L152-S156 VanDerWaalsContact O-N 3.12Å; L152-S156 PolarHBondContact O-OG 3.2Å; L152-S156 VanDerWaalsContact O-OG 3.05Å; L152-A224 HydrophobicContact CD1-CB 3.96Å; L152-A224 HydrophobicContact CG-CB 4.46Å; L152-I227 HydrophobicContact CD2-CB 3.86Å; L152-I227 HydrophobicContact CD2-CG2 3.53Å; L152-S228 WeakPolarHBondContact CD2-OG 3.42Å; L152-F231 HydrophobicContact CD2-CD2 4.15Å; L152-F231 HydrophobicContact CD2-CE2 4.06Å; L152-L285 HydrophobicContact CD1-CD1 3.63Å
153	G	94.9	Very high	94.7	Very high	0 Å²	0	10 Å²	10	0%	0	5%	0.051	C	C	.	.	H	α-helix	trans	-66.8	-42.2	-179.7	0	0	0	0	0	114.6	G149 M150 S156 Q157 T401	G149-G153 PolarHBondContact O-N 3.42Å; M150-G153 PolarHBondContact O-N 3.22Å; G153-S156 PolarHBondContact O-OG 3.22Å; G153-Q157 WeakPolarHBondContact O-CG 3.27Å; G153-Q157 PolarHBondContact O-N 3.13Å; G153-T401 WeakPolarHBondContact CA-OG1 3.49Å
154	V	96	Very high	94.7	Very high	9 Å²	9	10 Å²	10	6%	0.055	5%	0.052	C	C	.	.	H	α-helix	trans	-76.6	-40.7	-179.1	178.6	0	0	0	0	111.5	M150 S156 Q157 A158 I186 L190 W398	M150-V154 WeakPolarHBondContact O-CG2 3.43Å; M150-V154 PolarHBondContact O-N 2.98Å; V154-S156 VanDerWaalsContact C-N 3.32Å; V154-S156 PolarHBondContact O-N 3.44Å; V154-Q157 WeakPolarHBondContact O-CB 3.47Å; V154-Q157 PolarHBondContact O-N 3Å; V154-A158 PolarHBondContact O-N 3.46Å; V154-I186 HydrophobicContact CG1-CG2 4.04Å; V154-L190 HydrophobicContact CB-CD2 4.03Å; V154-L190 HydrophobicContact CG2-CD2 3.75Å; V154-W398 HydrophobicContact CG2-CH2 3.75Å; V154-W398 HydrophobicContact CG2-CZ3 3.72Å
155	S	96.3	Very high	94.6	Very high	2 Å²	2	11 Å²	11	1%	0.014	6%	0.061	C	C	.	.	H	α-helix	trans	-63.9	-38.4	176.8	57.8	0	0	0	0	112	C151 L152 Q157 A158 I159 S187 F231	C151-S155 WeakPolarHBondContact O-CB 3.42Å; C151-S155 PolarHBondContact O-N 3.04Å; C151-S155 PolarHBondContact O-OG 3.09Å; L152-S155 PolarHBondContact O-OG 3.39Å; S155-Q157 VanDerWaalsContact C-N 3.32Å; S155-Q157 PolarHBondContact O-N 3.47Å; S155-A158 WeakPolarHBondContact O-CB 3.31Å; S155-A158 PolarHBondContact O-N 3.19Å; S155-I159 PolarHBondContact O-N 3.06Å; S155-S187 WeakPolarHBondContact CA-OG 3.37Å; S155-S187 WeakPolarHBondContact CB-OG 3.1Å; S155-S187 PolarHBondContact N-OG 3.33Å; S155-F231 WeakPolarHBondContact OG-CB 3.44Å; S155-F231 WeakPolarHBondContact OG-CD2 3.16Å
156	S	96.2	Very high	94.3	Very high	4 Å²	4	13.9 Å²	13.9	3%	0.028	8%	0.079	C	C	.	.	H	α-helix	trans	-69.2	-29.1	177.9	70.1	0	0	0	0	113.3	L152 G153 V154 I159 M160 T405	L152-S156 VanDerWaalsContact O-CB 3.26Å; L152-S156 WeakPolarHBondContact O-CB 3.4Å; L152-S156 PolarHBondContact O-N 3.1Å; L152-S156 VanDerWaalsContact O-N 3.12Å; L152-S156 PolarHBondContact O-OG 3.2Å; L152-S156 VanDerWaalsContact O-OG 3.05Å; G153-S156 PolarHBondContact O-OG 3.22Å; V154-S156 VanDerWaalsContact C-N 3.32Å; V154-S156 PolarHBondContact O-N 3.44Å; S156-I159 PolarHBondContact O-N 3.38Å; S156-M160 PolarHBondContact O-N 3.04Å; S156-T405 WeakPolarHBondContact CB-OG1 3.31Å; S156-T405 PolarHBondContact OG-OG1 3.41Å
157	Q	96	Very high	94.2	Very high	4 Å²	4	13.7 Å²	13.7	2%	0.019	8%	0.078	C	C	.	.	H	α-helix	trans	-61.2	-46.4	168.4	-77	-72.9	-18.9	0	0	111.6	G153 V154 S155 I159 M160 W161 L183 T405 A434 V438	G153-Q157 WeakPolarHBondContact O-CG 3.27Å; G153-Q157 PolarHBondContact O-N 3.13Å; V154-Q157 WeakPolarHBondContact O-CB 3.47Å; V154-Q157 PolarHBondContact O-N 3Å; S155-Q157 VanDerWaalsContact C-N 3.32Å; S155-Q157 PolarHBondContact O-N 3.47Å; Q157-I159 VanDerWaalsContact C-N 3.27Å; Q157-I159 PolarHBondContact O-N 3.01Å; Q157-M160 PolarHBondContact O-N 3.08Å; Q157-M160 VanDerWaalsContact O-N 3.11Å; Q157-W161 PolarHBondContact O-N 2.83Å; Q157-L183 HydrophobicContact CB-CD1 4.29Å; Q157-T405 VanDerWaalsContact CD-CG2 3.45Å; Q157-T405 HydrophobicContact CG-CG2 3.79Å; Q157-A434 VanDerWaalsContact NE2-C 3.25Å; Q157-A434 PolarHBondContact NE2-O 2.83Å; Q157-V438 HydrophobicContact CG-CB 4.05Å; Q157-V438 HydrophobicContact CG-CG1 4.06Å; Q157-V438 HydrophobicContact CG-CG2 3.62Å
158	A	96	Very high	93.8	Very high	1 Å²	1	19.8 Å²	19.8	1%	0.008	11%	0.106	C	C	.	.	H	α-helix	trans	-57.1	-42.9	177.2	0	0	0	0	0	111.5	V154 S155 M160 W161 K162 N180 L183 W184	V154-A158 PolarHBondContact O-N 3.46Å; S155-A158 WeakPolarHBondContact O-CB 3.31Å; S155-A158 PolarHBondContact O-N 3.19Å; A158-M160 PolarHBondContact O-N 3.33Å; A158-W161 PolarHBondContact O-N 3.02Å; A158-K162 WeakPolarHBondContact O-CB 3.13Å; A158-K162 PolarHBondContact O-N 2.92Å; A158-N180 PolarHBondContact O-OD1 3.4Å; A158-L183 HydrophobicContact CB-CB 3.93Å; A158-W184 HydrophobicContact CB-CB 4.27Å
159	I	95.5	Very high	93.2	Very high	19 Å²	19	19.6 Å²	19.6	10%	0.097	11%	0.107	C	C	.	.	H	α-helix	trans	-60.9	-45.6	175.1	-60.7	169.2	0	0	0	111.7	S155 S156 Q157 K162 T163 F231 L234	S155-I159 PolarHBondContact O-N 3.06Å; S156-I159 PolarHBondContact O-N 3.38Å; Q157-I159 VanDerWaalsContact C-N 3.27Å; Q157-I159 PolarHBondContact O-N 3.01Å; I159-K162 WeakPolarHBondContact O-CB 3.15Å; I159-K162 PolarHBondContact O-N 3.47Å; I159-T163 WeakPolarHBondContact O-CB 3.46Å; I159-T163 PolarHBondContact O-N 2.76Å; I159-T163 PolarHBondContact O-OG1 2.71Å; I159-F231 HydrophobicContact CD1-CB 3.76Å; I159-F231 HydrophobicContact CD1-CD1 4.04Å; I159-F231 HydrophobicContact CD1-CG 3.9Å; I159-F231 WeakPolarHBondContact CD1-O 3.42Å; I159-L234 HydrophobicContact CD1-CB 3.86Å; I159-L234 HydrophobicContact CD1-CD1 4.39Å; I159-L234 HydrophobicContact CG1-CB 4.15Å
160	M	96.2	Very high	92.7	Very high	0 Å²	0	19.3 Å²	19.3	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-61.5	-47.8	179.3	-175.6	-168	77	0	0	111.2	S156 Q157 A158 K162 T163 L164 T405 A408 S409 I412 A434	S156-M160 PolarHBondContact O-N 3.04Å; Q157-M160 PolarHBondContact O-N 3.08Å; Q157-M160 VanDerWaalsContact O-N 3.11Å; A158-M160 PolarHBondContact O-N 3.33Å; M160-K162 VanDerWaalsContact C-N 3.34Å; M160-K162 PolarHBondContact O-N 2.88Å; M160-T163 CarbonylContact O-C 3.55Å; M160-T163 WeakPolarHBondContact O-CA 3.39Å; M160-T163 WeakPolarHBondContact O-CB 3.28Å; M160-T163 PolarHBondContact O-N 3.21Å; M160-T163 VanDerWaalsContact O-N 3.07Å; M160-L164 WeakPolarHBondContact O-CB 3.39Å; M160-L164 PolarHBondContact O-N 3.02Å; M160-T405 HydrophobicContact SD-CG2 4.24Å; M160-A408 HydrophobicContact CG-CB 4.17Å; M160-A408 HydrophobicContact SD-CB 3.58Å; M160-A408 VanDerWaalsContact SD-CB 3.58Å; M160-S409 WeakPolarHBondContact CA-OG 3.36Å; M160-S409 WeakPolarHBondContact CB-OG 3.5Å; M160-I412 HydrophobicContact CG-CD1 4.13Å; M160-A434 HydrophobicContact SD-CB 3.8Å
161	W	95.1	Very high	92.2	Very high	44 Å²	44	24.7 Å²	24.7	17%	0.167	13%	0.126	C	C	.	.	H	α-helix	trans	-65.9	-35	178.5	-78.2	97.1	0	0	0	112.7	Q157 A158 T163 L164 A165 V175 I179 N180 L183 T435	Q157-W161 PolarHBondContact O-N 2.83Å; A158-W161 PolarHBondContact O-N 3.02Å; W161-T163 VanDerWaalsContact C-N 3.34Å; W161-L164 HydrophobicContact CE3-CD2 4.03Å; W161-L164 HydrophobicContact CZ3-CD2 3.98Å; W161-L164 PolarHBondContact O-N 2.71Å; W161-A165 WeakPolarHBondContact O-CB 3.34Å; W161-A165 PolarHBondContact O-N 3.02Å; W161-V175 HydrophobicContact CE3-CG1 3.68Å; W161-V175 HydrophobicContact CZ3-CG1 3.78Å; W161-V175 HydrophobicContact CZ3-CG2 4.37Å; W161-I179 HydrophobicContact CB-CG2 4.31Å; W161-I179 HydrophobicContact CD2-CB 4.37Å; W161-I179 HydrophobicContact CD2-CG2 3.5Å; W161-I179 HydrophobicContact CE3-CB 4.08Å; W161-I179 HydrophobicContact CE3-CD1 3.89Å; W161-I179 HydrophobicContact CE3-CG2 3.65Å; W161-I179 HydrophobicContact CG-CG2 3.81Å; W161-I179 HydrophobicContact CH2-CD1 4.13Å; W161-I179 HydrophobicContact CZ2-CG2 4.45Å; W161-I179 HydrophobicContact CZ3-CD1 3.54Å; W161-I179 HydrophobicContact CZ3-CG2 4.19Å; W161-N180 HydrophobicContact CB-CB 4.45Å; W161-L183 HydrophobicContact CB-CD1 4.23Å; W161-L183 HydrophobicContact CG-CD1 3.74Å; W161-T435 HydrophobicContact CZ2-CG2 4.21Å
162	K	93.6	Very high	91.6	Very high	34 Å²	34	29.4 Å²	29.4	15%	0.148	15%	0.147	C	C	.	.	H	α-helix	trans	-60.7	-45.3	168.6	-176.8	177.4	168.4	179.2	0	111.2	A158 I159 M160 L164 A165 T166 N180 L234 I236	A158-K162 WeakPolarHBondContact O-CB 3.13Å; A158-K162 PolarHBondContact O-N 2.92Å; I159-K162 WeakPolarHBondContact O-CB 3.15Å; I159-K162 PolarHBondContact O-N 3.47Å; M160-K162 VanDerWaalsContact C-N 3.34Å; M160-K162 PolarHBondContact O-N 2.88Å; K162-L164 VanDerWaalsContact C-N 3.34Å; K162-A165 PolarHBondContact O-N 2.98Å; K162-T166 WeakPolarHBondContact O-CB 3.27Å; K162-T166 WeakPolarHBondContact O-CG2 3.47Å; K162-T166 PolarHBondContact O-N 3.12Å; K162-T166 VanDerWaalsContact O-N 3.11Å; K162-T166 PolarHBondContact O-OG1 2.94Å; K162-N180 HydrophobicContact CB-CB 4.35Å; K162-N180 WeakPolarHBondContact CB-ND2 3.36Å; K162-L234 PolarHBondContact NZ-O 3.48Å; K162-I236 WeakPolarHBondContact CE-O 3.26Å; K162-I236 PolarHBondContact NZ-O 3.31Å
163	T	93.1	Very high	91.1	Very high	17 Å²	17	31.9 Å²	31.9	10%	0.104	16%	0.16	C	C	.	.	H	α-helix	trans	-64.3	-41.9	-179.5	-56.7	0	0	0	0	110.7	I159 M160 W161 T166 T167 I412 K413	I159-T163 WeakPolarHBondContact O-CB 3.46Å; I159-T163 PolarHBondContact O-N 2.76Å; I159-T163 PolarHBondContact O-OG1 2.71Å; M160-T163 CarbonylContact O-C 3.55Å; M160-T163 WeakPolarHBondContact O-CA 3.39Å; M160-T163 WeakPolarHBondContact O-CB 3.28Å; M160-T163 PolarHBondContact O-N 3.21Å; M160-T163 VanDerWaalsContact O-N 3.07Å; W161-T163 VanDerWaalsContact C-N 3.34Å; T163-T166 PolarHBondContact O-N 3.19Å; T163-T166 PolarHBondContact O-OG1 2.94Å; T163-T167 VanDerWaalsContact O-CB 3.27Å; T163-T167 WeakPolarHBondContact O-CB 3.27Å; T163-T167 PolarHBondContact O-N 2.8Å; T163-T167 PolarHBondContact O-OG1 3.19Å; T163-I412 HydrophobicContact CG2-CB 4.15Å; T163-I412 HydrophobicContact CG2-CD1 4.47Å; T163-I412 HydrophobicContact CG2-CG2 3.8Å; T163-K413 HydrophobicContact CG2-CD 4.27Å; T163-K413 HydrophobicContact CG2-CG 4.17Å
164	L	93.1	Very high	90.5	Very high	10 Å²	10	39.5 Å²	39.5	5%	0.052	20%	0.195	C	C	.	.	H	α-helix	trans	-63.3	-43.4	176.5	-165.8	67.1	0	0	0	112.1	M160 W161 K162 T166 E170 L173 V175 I412	M160-L164 WeakPolarHBondContact O-CB 3.39Å; M160-L164 PolarHBondContact O-N 3.02Å; W161-L164 HydrophobicContact CE3-CD2 4.03Å; W161-L164 HydrophobicContact CZ3-CD2 3.98Å; W161-L164 PolarHBondContact O-N 2.71Å; K162-L164 VanDerWaalsContact C-N 3.34Å; L164-T166 VanDerWaalsContact C-N 3.34Å; L164-T166 PolarHBondContact O-N 3.2Å; L164-E170 HydrophobicContact CD1-CB 3.94Å; L164-E170 HydrophobicContact CD1-CG 3.81Å; L164-L173 HydrophobicContact CD1-CD1 3.85Å; L164-L173 HydrophobicContact CD2-CD1 4.42Å; L164-L173 HydrophobicContact CG-CD1 4.33Å; L164-V175 HydrophobicContact CD2-CG1 4.33Å; L164-V175 HydrophobicContact CD2-CG2 3.76Å; L164-V175 HydrophobicContact CG-CG2 4.04Å; L164-I412 HydrophobicContact CB-CD1 4.04Å; L164-I412 HydrophobicContact CD1-CD1 3.81Å; L164-I412 HydrophobicContact CD1-CG1 3.98Å
165	A	90.8	Very high	89.9	Confident	33 Å²	33	40.6 Å²	40.6	27%	0.273	20%	0.201	S	C	.	.	H	α-helix	trans	-72.7	-21.9	-179.6	0	0	0	0	0	114.4	W161 K162 V175	W161-A165 WeakPolarHBondContact O-CB 3.34Å; W161-A165 PolarHBondContact O-N 3.02Å; K162-A165 PolarHBondContact O-N 2.98Å; A165-V175 HydrophobicContact CB-CG1 4.21Å
166	T	87.5	Confident	89.3	Confident	63 Å²	63	44 Å²	44	39%	0.387	22%	0.222	S	C	.	.	H	α-helix	trans	-104.3	-5.5	-174.9	53.4	0	0	0	0	114.1	K162 T163 L164	K162-T166 WeakPolarHBondContact O-CB 3.27Å; K162-T166 WeakPolarHBondContact O-CG2 3.47Å; K162-T166 PolarHBondContact O-N 3.12Å; K162-T166 VanDerWaalsContact O-N 3.11Å; K162-T166 PolarHBondContact O-OG1 2.94Å; T163-T166 PolarHBondContact O-N 3.19Å; T163-T166 PolarHBondContact O-OG1 2.94Å; L164-T166 VanDerWaalsContact C-N 3.34Å; L164-T166 PolarHBondContact O-N 3.2Å
167	T	89.7	Confident	88.8	Confident	4 Å²	4	47.3 Å²	47.3	3%	0.025	24%	0.237	C	C	.	.			trans	-96.4	125.4	-176.5	-61	0	0	0	0	109.8	T163 A169 E170 I412 K413 D416	T163-T167 VanDerWaalsContact O-CB 3.27Å; T163-T167 WeakPolarHBondContact O-CB 3.27Å; T163-T167 PolarHBondContact O-N 2.8Å; T163-T167 PolarHBondContact O-OG1 3.19Å; T167-A169 VanDerWaalsContact C-N 3.34Å; T167-A169 HydrophobicContact CG2-CB 4.43Å; T167-A169 PolarHBondContact O-N 3.5Å; T167-E170 HydrophobicContact CG2-CG 4.43Å; T167-E170 PolarHBondContact O-N 2.85Å; T167-E170 VanDerWaalsContact O-N 3.17Å; T167-I412 HydrophobicContact CG2-CG2 3.82Å; T167-K413 PolarHBondContact OG1-NZ 2.71Å; T167-D416 HydrophobicContact CG2-CB 3.47Å; T167-D416 VanDerWaalsContact CG2-CB 3.47Å; T167-D416 VanDerWaalsContact CG2-OD1 3.29Å; T167-D416 WeakPolarHBondContact CG2-OD1 3.22Å
168	E	85.4	Confident	88.5	Confident	127 Å²	127	51.5 Å²	51.5	59%	0.593	26%	0.263	S	S	*	.	G	3₁₀ helix	trans	-66.6	-34.6	-172	-72.4	-65.5	143.5	0	0	112.4	E170 K171 D416	E168-E170 PolarHBondContact O-N 2.82Å; E168-K171 VanDerWaalsContact O-CB 3.27Å; E168-K171 WeakPolarHBondContact O-CB 3.05Å; E168-K171 PolarHBondContact O-N 2.98Å; E168-K171 VanDerWaalsContact O-N 3.16Å; E168-K171 IonicContact OE1-NZ 3.8Å; E168-K171 WeakPolarHBondContact OE2-CD 3.47Å; E168-K171 IonicContact OE2-NZ 2.9Å; E168-K171 PolarHBondContact OE2-NZ 3.16Å; E168-D416 PolarHBondContact N-OD1 3.07Å
169	A	81.2	Confident	88.3	Confident	7 Å²	7	54.5 Å²	54.5	6%	0.058	28%	0.278	C	S	.	.	G	3₁₀ helix	trans	-57.7	-23.9	176.3	0	0	0	0	0	114.1	T167 F172 S415 D416 K424	T167-A169 VanDerWaalsContact C-N 3.34Å; T167-A169 HydrophobicContact CG2-CB 4.43Å; T167-A169 PolarHBondContact O-N 3.5Å; A169-F172 WeakPolarHBondContact O-CD1 3.43Å; A169-F172 VanDerWaalsContact O-CE1 3.25Å; A169-F172 WeakPolarHBondContact O-CE1 3.49Å; A169-S415 WeakPolarHBondContact CB-O 3.49Å; A169-D416 HydrophobicContact CB-CB 4.41Å; A169-D416 PolarHBondContact N-OD1 3.32Å; A169-K424 VanDerWaalsContact O-CE 3.23Å; A169-K424 WeakPolarHBondContact O-CE 3.32Å; A169-K424 PolarHBondContact O-NZ 2.85Å
170	E	84.1	Confident	88.1	Confident	2 Å²	2	53.6 Å²	53.6	1%	0.009	27%	0.274	C	S	.	.	G	3₁₀ helix	trans	-102.6	3.2	-175	-60.1	-63.4	167.3	0	0	113.4	L164 T167 E168 F172 L173 I412 S427	L164-E170 HydrophobicContact CD1-CB 3.94Å; L164-E170 HydrophobicContact CD1-CG 3.81Å; T167-E170 HydrophobicContact CG2-CG 4.43Å; T167-E170 PolarHBondContact O-N 2.85Å; T167-E170 VanDerWaalsContact O-N 3.17Å; E168-E170 PolarHBondContact O-N 2.82Å; E170-F172 PolarHBondContact O-N 2.68Å; E170-F172 VanDerWaalsContact OE2-CE1 3.22Å; E170-F172 WeakPolarHBondContact OE2-CE1 3.3Å; E170-F172 WeakPolarHBondContact OE2-CZ 3.46Å; E170-L173 HydrophobicContact CB-CD1 4.3Å; E170-L173 WeakPolarHBondContact O-CB 3.49Å; E170-L173 PolarHBondContact O-N 3.33Å; E170-L173 WeakPolarHBondContact OE2-CD1 3.31Å; E170-I412 HydrophobicContact CG-CG2 3.99Å; E170-S427 WeakPolarHBondContact OE1-CB 3.26Å; E170-S427 PolarHBondContact OE1-OG 3.37Å
171	K	82.7	Confident	88	Confident	130 Å²	130	55.7 Å²	55.7	57%	0.565	28%	0.284	S	S	*	.	G	3₁₀ helix	trans	-57.7	-25.9	180	-165.4	176	-159.2	156.8	0	113.5	E168 L173 H174	E168-K171 VanDerWaalsContact O-CB 3.27Å; E168-K171 WeakPolarHBondContact O-CB 3.05Å; E168-K171 PolarHBondContact O-N 2.98Å; E168-K171 VanDerWaalsContact O-N 3.16Å; E168-K171 IonicContact OE1-NZ 3.8Å; E168-K171 WeakPolarHBondContact OE2-CD 3.47Å; E168-K171 IonicContact OE2-NZ 2.9Å; E168-K171 PolarHBondContact OE2-NZ 3.16Å; K171-L173 PolarHBondContact O-N 3.47Å; K171-H174 PolarHBondContact O-N 3.27Å; K171-H174 VanDerWaalsContact O-N 3.09Å
172	F	85.3	Confident	88	Confident	98 Å²	98	57.4 Å²	57.4	43%	0.43	30%	0.298	S	S	.	.	G	3₁₀ helix	trans	-63.4	-23	175.9	73.6	-86.8	0	0	0	113.5	A169 E170 H174 K424 V428	A169-F172 WeakPolarHBondContact O-CD1 3.43Å; A169-F172 VanDerWaalsContact O-CE1 3.25Å; A169-F172 WeakPolarHBondContact O-CE1 3.49Å; E170-F172 PolarHBondContact O-N 2.68Å; E170-F172 VanDerWaalsContact OE2-CE1 3.22Å; E170-F172 WeakPolarHBondContact OE2-CE1 3.3Å; E170-F172 WeakPolarHBondContact OE2-CZ 3.46Å; F172-H174 PolarHBondContact O-CD2 2.99Å; F172-H174 VanDerWaalsContact O-CD2 3.24Å; F172-H174 PolarHBondContact O-N 2.98Å; F172-K424 HydrophobicContact CD1-CD 4.28Å; F172-K424 HydrophobicContact CE1-CB 4.15Å; F172-K424 HydrophobicContact CE1-CD 3.85Å; F172-K424 HydrophobicContact CE1-CG 4.09Å; F172-K424 HydrophobicContact CZ-CB 4.19Å; F172-V428 HydrophobicContact CE2-CG2 4.37Å; F172-V428 HydrophobicContact CZ-CG2 3.93Å
173	L	83.9	Confident	88.1	Confident	62 Å²	62	57.5 Å²	57.5	33%	0.325	30%	0.301	S	S	.	.	G	3₁₀ helix	trans	-76.8	-10.9	176.4	-68.3	164.1	0	0	0	112.5	L164 E170 K171 V175 V428	L164-L173 HydrophobicContact CD1-CD1 3.85Å; L164-L173 HydrophobicContact CD2-CD1 4.42Å; L164-L173 HydrophobicContact CG-CD1 4.33Å; E170-L173 HydrophobicContact CB-CD1 4.3Å; E170-L173 WeakPolarHBondContact O-CB 3.49Å; E170-L173 PolarHBondContact O-N 3.33Å; E170-L173 WeakPolarHBondContact OE2-CD1 3.31Å; K171-L173 PolarHBondContact O-N 3.47Å; L173-V175 HydrophobicContact CB-CG2 3.63Å; L173-V175 HydrophobicContact CD1-CG2 4.47Å; L173-V175 PolarHBondContact O-N 3.05Å; L173-V175 VanDerWaalsContact O-N 3.14Å; L173-V428 HydrophobicContact CD1-CG2 3.89Å; L173-V428 HydrophobicContact CD2-CG2 3.93Å; L173-V428 HydrophobicContact CG-CG2 4.35Å
174	H	82.8	Confident	88.3	Confident	160 Å²	160	57.7 Å²	57.7	74%	0.741	30%	0.299	S	S	*	.			trans	50.5	36.7	-177	-62.9	-78.3	0	0	0	113.3	K171 F172 T176	K171-H174 PolarHBondContact O-N 3.27Å; K171-H174 VanDerWaalsContact O-N 3.09Å; F172-H174 PolarHBondContact O-CD2 2.99Å; F172-H174 VanDerWaalsContact O-CD2 3.24Å; F172-H174 PolarHBondContact O-N 2.98Å; H174-T176 PolarHBondContact O-N 3.08Å
175	V	82.4	Confident	88.5	Confident	31 Å²	31	63.4 Å²	63.4	19%	0.188	32%	0.32	C	S	.	.			trans	-68.5	121.1	-178.2	176.9	0	0	0	0	109.6	W161 L164 A165 L173 I179	W161-V175 HydrophobicContact CE3-CG1 3.68Å; W161-V175 HydrophobicContact CZ3-CG1 3.78Å; W161-V175 HydrophobicContact CZ3-CG2 4.37Å; L164-V175 HydrophobicContact CD2-CG1 4.33Å; L164-V175 HydrophobicContact CD2-CG2 3.76Å; L164-V175 HydrophobicContact CG-CG2 4.04Å; A165-V175 HydrophobicContact CB-CG1 4.21Å; L173-V175 HydrophobicContact CB-CG2 3.63Å; L173-V175 HydrophobicContact CD1-CG2 4.47Å; L173-V175 PolarHBondContact O-N 3.05Å; L173-V175 VanDerWaalsContact O-N 3.14Å; V175-I179 HydrophobicContact CG1-CD1 4.45Å
176	T	85.2	Confident	88.8	Confident	74 Å²	74	65.8 Å²	65.8	45%	0.454	33%	0.327	S	S	.	.			trans	-78.4	145.4	179.3	88.3	0	0	0	0	110.3	H174 V178 I179	H174-T176 PolarHBondContact O-N 3.08Å; T176-V178 PolarHBondContact O-N 3.32Å; T176-V178 VanDerWaalsContact O-N 3.13Å; T176-V178 VanDerWaalsContact OG1-CB 3.3Å; T176-V178 WeakPolarHBondContact OG1-CB 3.33Å; T176-V178 PolarHBondContact OG1-N 3.35Å; T176-I179 PolarHBondContact O-N 3.47Å
177	Q	84.6	Confident	89.3	Confident	73 Å²	73	62.8 Å²	62.8	34%	0.341	31%	0.309	S	S	.	.	H	α-helix	trans	-67.7	-10.1	174.2	-164.1	166.1	-5.1	0	0	112.6	I179 N180 H181	Q177-I179 VanDerWaalsContact C-N 3.28Å; Q177-I179 PolarHBondContact O-N 3.39Å; Q177-N180 PolarHBondContact O-N 3.28Å; Q177-H181 PolarHBondContact O-CD2 3.35Å; Q177-H181 VanDerWaalsContact O-CD2 3.31Å; Q177-H181 PolarHBondContact O-N 3.02Å; Q177-H181 VanDerWaalsContact O-N 3.13Å
178	V	90.5	Very high	89.6	Confident	93 Å²	93	64.3 Å²	64.3	56%	0.564	32%	0.317	S	S	*	.	H	α-helix	trans	-61.3	-37.4	177.2	-175.6	0	0	0	0	111.1	T176 N180 H181 V182	T176-V178 PolarHBondContact O-N 3.32Å; T176-V178 VanDerWaalsContact O-N 3.13Å; T176-V178 VanDerWaalsContact OG1-CB 3.3Å; T176-V178 WeakPolarHBondContact OG1-CB 3.33Å; T176-V178 PolarHBondContact OG1-N 3.35Å; V178-N180 PolarHBondContact O-N 3.14Å; V178-H181 WeakPolarHBondContact O-CB 3.25Å; V178-H181 PolarHBondContact O-N 3.3Å; V178-H181 VanDerWaalsContact O-N 3.16Å; V178-V182 HydrophobicContact CG1-CG2 4.3Å; V178-V182 WeakPolarHBondContact O-CG2 3.47Å; V178-V182 PolarHBondContact O-N 2.99Å
179	I	91.8	Very high	90.2	Very high	63 Å²	63	63.6 Å²	63.6	32%	0.323	32%	0.317	S	S	.	.	H	α-helix	trans	-63.1	-45.1	-179.7	-59	174.4	0	0	0	110.5	W161 V175 T176 Q177 H181 V182 L183	W161-I179 HydrophobicContact CB-CG2 4.31Å; W161-I179 HydrophobicContact CD2-CB 4.37Å; W161-I179 HydrophobicContact CD2-CG2 3.5Å; W161-I179 HydrophobicContact CE3-CB 4.08Å; W161-I179 HydrophobicContact CE3-CD1 3.89Å; W161-I179 HydrophobicContact CE3-CG2 3.65Å; W161-I179 HydrophobicContact CG-CG2 3.81Å; W161-I179 HydrophobicContact CH2-CD1 4.13Å; W161-I179 HydrophobicContact CZ2-CG2 4.45Å; W161-I179 HydrophobicContact CZ3-CD1 3.54Å; W161-I179 HydrophobicContact CZ3-CG2 4.19Å; V175-I179 HydrophobicContact CG1-CD1 4.45Å; T176-I179 PolarHBondContact O-N 3.47Å; Q177-I179 VanDerWaalsContact C-N 3.28Å; Q177-I179 PolarHBondContact O-N 3.39Å; I179-H181 VanDerWaalsContact C-N 3.35Å; I179-H181 PolarHBondContact O-N 3.49Å; I179-V182 PolarHBondContact O-N 2.79Å; I179-L183 HydrophobicContact CG2-CD1 3.89Å; I179-L183 HydrophobicContact CG2-CG 4.42Å; I179-L183 WeakPolarHBondContact O-CB 3.35Å; I179-L183 WeakPolarHBondContact O-CG 3.48Å; I179-L183 PolarHBondContact O-N 3.39Å
180	N	92.1	Very high	91	Very high	1 Å²	1	65.3 Å²	65.3	1%	0.005	33%	0.325	C	S	.	.	H	α-helix	trans	-58.2	-46.9	173.3	174.5	33	0	0	0	111.2	A158 W161 K162 Q177 V178 V182 L183 W184 G235	A158-N180 PolarHBondContact O-OD1 3.4Å; W161-N180 HydrophobicContact CB-CB 4.45Å; K162-N180 HydrophobicContact CB-CB 4.35Å; K162-N180 WeakPolarHBondContact CB-ND2 3.36Å; Q177-N180 PolarHBondContact O-N 3.28Å; V178-N180 PolarHBondContact O-N 3.14Å; N180-V182 PolarHBondContact O-N 2.74Å; N180-L183 PolarHBondContact O-N 2.85Å; N180-W184 WeakPolarHBondContact O-CB 3.25Å; N180-W184 PolarHBondContact O-N 3.01Å; N180-G235 PolarHBondContact OD1-O 3.48Å
181	H	93.8	Very high	91.7	Very high	44 Å²	44	65.8 Å²	65.8	20%	0.204	33%	0.327	C	S	.	.	H	α-helix	trans	-55.2	-49.1	177.6	-89.6	-80.9	0	0	0	113	Q177 V178 I179 W184 W185 P237 S239	Q177-H181 PolarHBondContact O-CD2 3.35Å; Q177-H181 VanDerWaalsContact O-CD2 3.31Å; Q177-H181 PolarHBondContact O-N 3.02Å; Q177-H181 VanDerWaalsContact O-N 3.13Å; V178-H181 WeakPolarHBondContact O-CB 3.25Å; V178-H181 PolarHBondContact O-N 3.3Å; V178-H181 VanDerWaalsContact O-N 3.16Å; I179-H181 VanDerWaalsContact C-N 3.35Å; I179-H181 PolarHBondContact O-N 3.49Å; H181-W184 PolarHBondContact O-N 2.61Å; H181-W185 PolarHBondContact O-N 3.47Å; H181-P237 WeakPolarHBondContact CE1-CB 3.31Å; H181-P237 WeakPolarHBondContact NE2-CB 3.28Å; H181-S239 PolarHBondContact CE1-OG 3.15Å; H181-S239 PolarHBondContact NE2-OG 2.88Å
182	V	95.5	Very high	92.4	Very high	79 Å²	79	63.7 Å²	63.7	48%	0.479	32%	0.322	S	S	.	.	H	α-helix	trans	-63	-48.9	-179.4	172.3	0	0	0	0	110.5	V178 I179 N180 W184 W185 I186	V178-V182 HydrophobicContact CG1-CG2 4.3Å; V178-V182 WeakPolarHBondContact O-CG2 3.47Å; V178-V182 PolarHBondContact O-N 2.99Å; I179-V182 PolarHBondContact O-N 2.79Å; N180-V182 PolarHBondContact O-N 2.74Å; V182-W184 VanDerWaalsContact C-N 3.31Å; V182-W184 PolarHBondContact O-N 3.06Å; V182-W185 PolarHBondContact O-N 3.19Å; V182-I186 HydrophobicContact CG1-CD1 3.78Å; V182-I186 VanDerWaalsContact O-CG1 3.28Å; V182-I186 WeakPolarHBondContact O-CG1 3.26Å; V182-I186 PolarHBondContact O-N 2.95Å
183	L	95.5	Very high	93	Very high	37 Å²	37	61.4 Å²	61.4	19%	0.194	32%	0.321	C	S	.	.	H	α-helix	trans	-64.2	-36.1	179.6	-70.2	174.1	0	0	0	112.5	Q157 A158 W161 I179 N180 I186 S187	Q157-L183 HydrophobicContact CB-CD1 4.29Å; A158-L183 HydrophobicContact CB-CB 3.93Å; W161-L183 HydrophobicContact CB-CD1 4.23Å; W161-L183 HydrophobicContact CG-CD1 3.74Å; I179-L183 HydrophobicContact CG2-CD1 3.89Å; I179-L183 HydrophobicContact CG2-CG 4.42Å; I179-L183 WeakPolarHBondContact O-CB 3.35Å; I179-L183 WeakPolarHBondContact O-CG 3.48Å; I179-L183 PolarHBondContact O-N 3.39Å; N180-L183 PolarHBondContact O-N 2.85Å; L183-I186 PolarHBondContact O-N 2.8Å; L183-S187 VanDerWaalsContact O-CB 3.31Å; L183-S187 WeakPolarHBondContact O-CB 3.33Å; L183-S187 PolarHBondContact O-N 3.4Å
184	W	96.9	Very high	93.6	Very high	20 Å²	20	58.8 Å²	58.8	8%	0.076	31%	0.307	C	S	.	.	H	α-helix	trans	-65.1	-44.9	176.6	-174.3	85.9	0	0	0	111.7	A158 N180 H181 V182 S187 L188 L232 I236 P237 I240	A158-W184 HydrophobicContact CB-CB 4.27Å; N180-W184 WeakPolarHBondContact O-CB 3.25Å; N180-W184 PolarHBondContact O-N 3.01Å; H181-W184 PolarHBondContact O-N 2.61Å; V182-W184 VanDerWaalsContact C-N 3.31Å; V182-W184 PolarHBondContact O-N 3.06Å; W184-S187 WeakPolarHBondContact O-CB 3.5Å; W184-S187 PolarHBondContact O-N 3.2Å; W184-L188 HydrophobicContact CH2-CD2 4.06Å; W184-L188 HydrophobicContact CZ3-CD2 4.08Å; W184-L188 PolarHBondContact O-N 3.35Å; W184-L232 HydrophobicContact CD2-CD1 4.39Å; W184-L232 HydrophobicContact CG-CD1 4.49Å; W184-L232 HydrophobicContact CZ2-CD1 4.14Å; W184-L232 HydrophobicContact CZ2-CG 4.29Å; W184-L232 PolarHBondContact NE1-O 3.38Å; W184-I236 HydrophobicContact CZ2-CG1 3.71Å; W184-P237 HydrophobicContact CB-CG 4.31Å; W184-P237 HydrophobicContact CG-CG 4.33Å; W184-I240 HydrophobicContact CE3-CD1 4.07Å; W184-I240 HydrophobicContact CH2-CD1 4.47Å; W184-I240 HydrophobicContact CZ3-CD1 3.87Å
185	W	97.1	Very high	94.3	Very high	131 Å²	131	52.8 Å²	52.8	50%	0.496	28%	0.284	S	S	.	.	H	α-helix	trans	-64.2	-41.4	174.9	-80.3	114.6	0	0	0	112.5	H181 V182 S187 L188 L189 I240	H181-W185 PolarHBondContact O-N 3.47Å; V182-W185 PolarHBondContact O-N 3.19Å; W185-S187 VanDerWaalsContact C-N 3.32Å; W185-S187 PolarHBondContact O-N 3.17Å; W185-L188 HydrophobicContact CE3-CD2 3.7Å; W185-L188 HydrophobicContact CH2-CD2 4.49Å; W185-L188 HydrophobicContact CZ3-CD2 3.51Å; W185-L188 PolarHBondContact O-N 2.99Å; W185-L189 WeakPolarHBondContact O-CG 3.45Å; W185-L189 PolarHBondContact O-N 3Å; W185-I240 HydrophobicContact CZ2-CD1 4.41Å
186	I	97	Very high	95.1	Very high	82 Å²	82	55.7 Å²	55.7	42%	0.421	30%	0.297	S	S	.	.	H	α-helix	trans	-60.2	-45.4	173.8	-67.1	167.4	0	0	0	110.2	V154 V182 L183 L188 L189 L190	V154-I186 HydrophobicContact CG1-CG2 4.04Å; V182-I186 HydrophobicContact CG1-CD1 3.78Å; V182-I186 VanDerWaalsContact O-CG1 3.28Å; V182-I186 WeakPolarHBondContact O-CG1 3.26Å; V182-I186 PolarHBondContact O-N 2.95Å; L183-I186 PolarHBondContact O-N 2.8Å; I186-L188 VanDerWaalsContact C-N 3.34Å; I186-L188 PolarHBondContact O-N 3.26Å; I186-L189 PolarHBondContact O-N 3.16Å; I186-L190 VanDerWaalsContact O-CB 3.27Å; I186-L190 WeakPolarHBondContact O-CB 3.43Å; I186-L190 PolarHBondContact O-N 3.46Å
187	S	97.3	Very high	95.6	Very high	1 Å²	1	53.7 Å²	53.7	1%	0.007	29%	0.285	C	S	.	.	H	α-helix	trans	-61.5	-41.3	177.6	-176.4	0	0	0	0	112.3	S155 L183 W184 W185 L191	S155-S187 WeakPolarHBondContact CA-OG 3.37Å; S155-S187 WeakPolarHBondContact CB-OG 3.1Å; S155-S187 PolarHBondContact N-OG 3.33Å; L183-S187 VanDerWaalsContact O-CB 3.31Å; L183-S187 WeakPolarHBondContact O-CB 3.33Å; L183-S187 PolarHBondContact O-N 3.4Å; W184-S187 WeakPolarHBondContact O-CB 3.5Å; W184-S187 PolarHBondContact O-N 3.2Å; W185-S187 VanDerWaalsContact C-N 3.32Å; W185-S187 PolarHBondContact O-N 3.17Å; S187-L191 VanDerWaalsContact O-CB 3.26Å; S187-L191 WeakPolarHBondContact O-CB 3.44Å; S187-L191 PolarHBondContact O-N 3.4Å
188	L	97.7	Very high	96.2	Very high	36 Å²	36	50.9 Å²	50.9	19%	0.188	27%	0.272	C	S	.	.	H	α-helix	trans	-63.1	-50.1	177.3	175.3	64.3	0	0	0	110.7	W184 W185 I186 L190 L191 L192 L232	W184-L188 HydrophobicContact CH2-CD2 4.06Å; W184-L188 HydrophobicContact CZ3-CD2 4.08Å; W184-L188 PolarHBondContact O-N 3.35Å; W185-L188 HydrophobicContact CE3-CD2 3.7Å; W185-L188 HydrophobicContact CH2-CD2 4.49Å; W185-L188 HydrophobicContact CZ3-CD2 3.51Å; W185-L188 PolarHBondContact O-N 2.99Å; I186-L188 VanDerWaalsContact C-N 3.34Å; I186-L188 PolarHBondContact O-N 3.26Å; L188-L190 VanDerWaalsContact C-N 3.33Å; L188-L190 PolarHBondContact O-N 3.43Å; L188-L191 PolarHBondContact O-N 3.01Å; L188-L192 HydrophobicContact CD1-CD1 4.09Å; L188-L192 HydrophobicContact CD1-CG 4.26Å; L188-L192 HydrophobicContact CG-CD1 4.08Å; L188-L192 WeakPolarHBondContact O-CB 3.46Å; L188-L192 VanDerWaalsContact O-CG 3.31Å; L188-L192 WeakPolarHBondContact O-CG 3.2Å; L188-L192 PolarHBondContact O-N 3.39Å; L188-L232 HydrophobicContact CB-CD1 4.03Å; L188-L232 HydrophobicContact CD1-CD2 3.63Å
189	L	97.9	Very high	96.5	Very high	111 Å²	111	51.3 Å²	51.3	58%	0.581	27%	0.27	S	S	*	.	H	α-helix	trans	-61.9	-41.9	179.6	-69.1	174.6	0	0	0	111.7	W185 I186 L192 A193	W185-L189 WeakPolarHBondContact O-CG 3.45Å; W185-L189 PolarHBondContact O-N 3Å; I186-L189 PolarHBondContact O-N 3.16Å; L189-L192 PolarHBondContact O-N 2.89Å; L189-A193 WeakPolarHBondContact O-CB 3.13Å; L189-A193 PolarHBondContact O-N 3.12Å
190	L	97.1	Very high	96.7	Very high	44 Å²	44	53.5 Å²	53.5	23%	0.23	28%	0.277	C	S	.	.	H	α-helix	trans	-63.3	-46.8	176.4	-179.6	62.1	0	0	0	111.4	M150 V154 I186 L188 L192 A193 V194	M150-L190 HydrophobicContact CB-CD2 4.07Å; V154-L190 HydrophobicContact CB-CD2 4.03Å; V154-L190 HydrophobicContact CG2-CD2 3.75Å; I186-L190 VanDerWaalsContact O-CB 3.27Å; I186-L190 WeakPolarHBondContact O-CB 3.43Å; I186-L190 PolarHBondContact O-N 3.46Å; L188-L190 VanDerWaalsContact C-N 3.33Å; L188-L190 PolarHBondContact O-N 3.43Å; L190-L192 VanDerWaalsContact C-N 3.33Å; L190-L192 PolarHBondContact O-N 3.23Å; L190-A193 PolarHBondContact O-N 3.26Å; L190-V194 HydrophobicContact CD1-CG2 4.04Å; L190-V194 HydrophobicContact CG-CG2 4.46Å; L190-V194 WeakPolarHBondContact O-CB 3.46Å; L190-V194 WeakPolarHBondContact O-CG2 3.42Å; L190-V194 PolarHBondContact O-N 2.97Å
191	L	98.2	Very high	96.8	Very high	11 Å²	11	53.5 Å²	53.5	6%	0.058	28%	0.277	C	S	.	.	H	α-helix	trans	-61.7	-41.8	178.1	180	59.1	0	0	0	111.6	Y148 C151 S187 L188 S195 I229 L232	Y148-L191 HydrophobicContact CD1-CD1 4.13Å; Y148-L191 HydrophobicContact CE1-CD1 3.75Å; C151-L191 HydrophobicContact CB-CD1 4.15Å; S187-L191 VanDerWaalsContact O-CB 3.26Å; S187-L191 WeakPolarHBondContact O-CB 3.44Å; S187-L191 PolarHBondContact O-N 3.4Å; L188-L191 PolarHBondContact O-N 3.01Å; L191-S195 WeakPolarHBondContact O-CB 3.29Å; L191-S195 PolarHBondContact O-N 2.9Å; L191-S195 PolarHBondContact O-OG 3.16Å; L191-I229 HydrophobicContact CD2-CG1 3.93Å; L191-L232 HydrophobicContact CD2-CD2 4.17Å
192	L	98.2	Very high	96.9	Very high	86 Å²	86	53.3 Å²	53.3	45%	0.45	28%	0.279	S	S	.	.	H	α-helix	trans	-63	-48.2	174.8	-72.9	172.5	0	0	0	111.2	L188 L189 L190 V194 S195 I196	L188-L192 HydrophobicContact CD1-CD1 4.09Å; L188-L192 HydrophobicContact CD1-CG 4.26Å; L188-L192 HydrophobicContact CG-CD1 4.08Å; L188-L192 WeakPolarHBondContact O-CB 3.46Å; L188-L192 VanDerWaalsContact O-CG 3.31Å; L188-L192 WeakPolarHBondContact O-CG 3.2Å; L188-L192 PolarHBondContact O-N 3.39Å; L189-L192 PolarHBondContact O-N 2.89Å; L190-L192 VanDerWaalsContact C-N 3.33Å; L190-L192 PolarHBondContact O-N 3.23Å; L192-V194 PolarHBondContact O-N 2.95Å; L192-S195 PolarHBondContact O-N 3.38Å; L192-I196 VanDerWaalsContact O-CB 3.32Å; L192-I196 WeakPolarHBondContact O-CB 3.48Å; L192-I196 WeakPolarHBondContact O-CD1 3.33Å; L192-I196 WeakPolarHBondContact O-CG1 3.48Å; L192-I196 PolarHBondContact O-N 3.18Å
193	A	97.5	Very high	96.8	Very high	51 Å²	51	54.1 Å²	54.1	42%	0.421	28%	0.28	S	S	.	.	H	α-helix	trans	-60.9	-47.3	179.9	0	0	0	0	0	112.3	L189 L190 T197	L189-A193 WeakPolarHBondContact O-CB 3.13Å; L189-A193 PolarHBondContact O-N 3.12Å; L190-A193 PolarHBondContact O-N 3.26Å; A193-T197 WeakPolarHBondContact O-CB 3.11Å; A193-T197 PolarHBondContact O-N 3.32Å; A193-T197 PolarHBondContact O-OG1 2.92Å
194	V	97.3	Very high	96.6	Very high	6 Å²	6	55.8 Å²	55.8	4%	0.036	29%	0.289	C	S	.	.	H	α-helix	trans	-64.7	-42.7	177.5	172	0	0	0	0	110.6	F143 Y148 M150 L190 L192 T197 Y198	F143-V194 HydrophobicContact CE1-CG1 4.12Å; F143-V194 HydrophobicContact CZ-CB 4.39Å; F143-V194 HydrophobicContact CZ-CG1 3.97Å; F143-V194 HydrophobicContact CZ-CG2 4.28Å; Y148-V194 HydrophobicContact CD1-CG1 4.05Å; Y148-V194 HydrophobicContact CD2-CG1 3.75Å; Y148-V194 HydrophobicContact CE1-CG1 3.98Å; Y148-V194 HydrophobicContact CE2-CG1 3.7Å; Y148-V194 HydrophobicContact CG-CG1 3.95Å; M150-V194 HydrophobicContact CE-CG2 4.27Å; L190-V194 HydrophobicContact CD1-CG2 4.04Å; L190-V194 HydrophobicContact CG-CG2 4.46Å; L190-V194 WeakPolarHBondContact O-CB 3.46Å; L190-V194 WeakPolarHBondContact O-CG2 3.42Å; L190-V194 PolarHBondContact O-N 2.97Å; L192-V194 PolarHBondContact O-N 2.95Å; V194-T197 PolarHBondContact O-N 2.98Å; V194-Y198 WeakPolarHBondContact O-CB 3.3Å; V194-Y198 PolarHBondContact O-N 3.41Å
195	S	98	Very high	96.3	Very high	35 Å²	35	55.9 Å²	55.9	25%	0.245	29%	0.29	C	S	.	.	H	α-helix	trans	-69.9	-40.5	-179	-58.2	0	0	0	0	113.2	Y148 L191 L192 T197 Y198 L199	Y148-S195 WeakPolarHBondContact OH-CA 3.19Å; Y148-S195 WeakPolarHBondContact OH-CB 3.3Å; Y148-S195 PolarHBondContact OH-OG 2.82Å; L191-S195 WeakPolarHBondContact O-CB 3.29Å; L191-S195 PolarHBondContact O-N 2.9Å; L191-S195 PolarHBondContact O-OG 3.16Å; L192-S195 PolarHBondContact O-N 3.38Å; S195-T197 VanDerWaalsContact C-N 3.35Å; S195-Y198 PolarHBondContact O-N 3.33Å; S195-L199 WeakPolarHBondContact O-CB 3.39Å; S195-L199 PolarHBondContact O-N 3.25Å
196	I	97.8	Very high	95.9	Very high	91 Å²	91	54.4 Å²	54.4	47%	0.467	29%	0.287	S	S	.	.	H	α-helix	trans	-62.7	-45.4	174.4	-70.5	166.2	0	0	0	109.9	L192 Y198 L199 F200	L192-I196 VanDerWaalsContact O-CB 3.32Å; L192-I196 WeakPolarHBondContact O-CB 3.48Å; L192-I196 WeakPolarHBondContact O-CD1 3.33Å; L192-I196 WeakPolarHBondContact O-CG1 3.48Å; L192-I196 PolarHBondContact O-N 3.18Å; I196-Y198 PolarHBondContact O-N 3.25Å; I196-L199 PolarHBondContact O-N 3.38Å; I196-F200 HydrophobicContact CG2-CD2 3.77Å; I196-F200 HydrophobicContact CG2-CE2 3.41Å; I196-F200 VanDerWaalsContact CG2-CE2 3.41Å; I196-F200 HydrophobicContact CG2-CZ 4.46Å; I196-F200 WeakPolarHBondContact O-CD2 3.47Å; I196-F200 PolarHBondContact O-N 2.73Å
197	T	96.5	Very high	95.4	Very high	33 Å²	33	52.6 Å²	52.6	20%	0.202	28%	0.277	C	S	.	.	H	α-helix	trans	-60	-47.5	177.6	-57.3	0	0	0	0	111.5	F139 L140 F143 A193 V194 S195 F200 K201	F139-T197 HydrophobicContact CD1-CG2 4.49Å; F139-T197 HydrophobicContact CE1-CG2 3.68Å; F139-T197 HydrophobicContact CZ-CG2 4.44Å; L140-T197 HydrophobicContact CD2-CG2 4.01Å; L140-T197 WeakPolarHBondContact CD2-O 3.47Å; F143-T197 HydrophobicContact CB-CG2 4.46Å; F143-T197 HydrophobicContact CD1-CG2 3.76Å; F143-T197 HydrophobicContact CD2-CG2 4.08Å; F143-T197 HydrophobicContact CE1-CG2 3.93Å; F143-T197 HydrophobicContact CE2-CG2 4.22Å; F143-T197 HydrophobicContact CG-CG2 3.83Å; F143-T197 HydrophobicContact CZ-CG2 4.15Å; A193-T197 WeakPolarHBondContact O-CB 3.11Å; A193-T197 PolarHBondContact O-N 3.32Å; A193-T197 PolarHBondContact O-OG1 2.92Å; V194-T197 PolarHBondContact O-N 2.98Å; S195-T197 VanDerWaalsContact C-N 3.35Å; T197-F200 PolarHBondContact O-N 2.88Å; T197-K201 PolarHBondContact O-N 2.95Å
198	Y	97	Very high	95	Very high	14 Å²	14	52.5 Å²	52.5	6%	0.055	28%	0.276	C	S	.	.	H	α-helix	trans	-71.6	-30.4	-179.9	-161.1	-96.6	0	0	0	112.7	F143 I145 Y148 V194 S195 I196 K201 T202 V209 E212	F143-Y198 HydrophobicContact CD1-CD2 4.21Å; F143-Y198 HydrophobicContact CE1-CD2 4.45Å; I145-Y198 HydrophobicContact CB-CE2 3.82Å; I145-Y198 HydrophobicContact CD1-CD1 4.21Å; I145-Y198 HydrophobicContact CD1-CD2 4.4Å; I145-Y198 HydrophobicContact CD1-CE1 3.75Å; I145-Y198 HydrophobicContact CD1-CE2 3.97Å; I145-Y198 HydrophobicContact CG1-CE2 4.45Å; Y148-Y198 HydrophobicContact CE2-CD1 4.47Å; Y148-Y198 HydrophobicContact CE2-CG 4.17Å; V194-Y198 WeakPolarHBondContact O-CB 3.3Å; V194-Y198 PolarHBondContact O-N 3.41Å; S195-Y198 PolarHBondContact O-N 3.33Å; I196-Y198 PolarHBondContact O-N 3.25Å; Y198-K201 HydrophobicContact CD2-CD 4.05Å; Y198-K201 HydrophobicContact CE2-CD 3.81Å; Y198-K201 WeakPolarHBondContact O-CB 3.33Å; Y198-K201 PolarHBondContact O-N 3.3Å; Y198-T202 WeakPolarHBondContact O-CB 3.48Å; Y198-T202 PolarHBondContact O-N 3.35Å; Y198-T202 PolarHBondContact O-OG1 2.76Å; Y198-V209 HydrophobicContact CE1-CG1 4.43Å; Y198-E212 WeakPolarHBondContact CE2-OE2 3.39Å; Y198-E212 PolarHBondContact OH-OE2 3.45Å
199	L	96	Very high	94.7	Very high	101 Å²	101	51.3 Å²	51.3	53%	0.529	27%	0.27	S	S	.	.	H	α-helix	trans	-64.4	-44.5	172.3	-178	62.6	0	0	0	110.8	S195 I196 K201 T202 I203	S195-L199 WeakPolarHBondContact O-CB 3.39Å; S195-L199 PolarHBondContact O-N 3.25Å; I196-L199 PolarHBondContact O-N 3.38Å; L199-K201 VanDerWaalsContact C-N 3.33Å; L199-K201 PolarHBondContact O-N 3.14Å; L199-T202 WeakPolarHBondContact O-CB 3.47Å; L199-T202 PolarHBondContact O-N 3.35Å; L199-T202 VanDerWaalsContact O-N 3.11Å; L199-I203 HydrophobicContact CD1-CD1 4.14Å; L199-I203 HydrophobicContact CD1-CG1 4.41Å; L199-I203 HydrophobicContact CG-CD1 3.94Å; L199-I203 WeakPolarHBondContact O-CG1 3.43Å; L199-I203 PolarHBondContact O-N 3.18Å
200	F	96.4	Very high	94.3	Very high	110 Å²	110	50.7 Å²	50.7	48%	0.482	26%	0.26	S	S	.	.	H	α-helix	trans	-61.2	-41	172.5	-76.1	-58.2	0	0	0	112.3	L140 I196 T197 T202 I203 L204	L140-F200 HydrophobicContact CD1-CB 4.09Å; L140-F200 HydrophobicContact CD2-CB 4.17Å; I196-F200 HydrophobicContact CG2-CD2 3.77Å; I196-F200 HydrophobicContact CG2-CE2 3.41Å; I196-F200 VanDerWaalsContact CG2-CE2 3.41Å; I196-F200 HydrophobicContact CG2-CZ 4.46Å; I196-F200 WeakPolarHBondContact O-CD2 3.47Å; I196-F200 PolarHBondContact O-N 2.73Å; T197-F200 PolarHBondContact O-N 2.88Å; F200-T202 VanDerWaalsContact C-N 3.29Å; F200-T202 PolarHBondContact O-N 3.2Å; F200-I203 PolarHBondContact O-N 3.27Å; F200-L204 VanDerWaalsContact O-CB 3.3Å; F200-L204 WeakPolarHBondContact O-CB 3.47Å; F200-L204 WeakPolarHBondContact O-CG 3.15Å; F200-L204 PolarHBondContact O-N 3.09Å
201	K	95.3	Very high	93.8	Very high	0 Å²	0	48.7 Å²	48.7	0%	0	25%	0.25	C	C	.	.	H	α-helix	trans	-57.7	-43.6	171.8	-176.6	-175.1	-172.3	176	0	111.2	L140 F143 T197 Y198 L199 F205 V209 E212	L140-K201 HydrophobicContact CB-CB 4.32Å; L140-K201 HydrophobicContact CD2-CB 4.46Å; L140-K201 WeakPolarHBondContact O-CD 3.4Å; L140-K201 VanDerWaalsContact O-CE 3.24Å; L140-K201 WeakPolarHBondContact O-CE 3.45Å; L140-K201 VanDerWaalsContact O-CG 3.31Å; L140-K201 WeakPolarHBondContact O-CG 3.36Å; F143-K201 WeakPolarHBondContact O-CD 3.37Å; F143-K201 PolarHBondContact O-NZ 3.17Å; T197-K201 PolarHBondContact O-N 2.95Å; Y198-K201 HydrophobicContact CD2-CD 4.05Å; Y198-K201 HydrophobicContact CE2-CD 3.81Å; Y198-K201 WeakPolarHBondContact O-CB 3.33Å; Y198-K201 PolarHBondContact O-N 3.3Å; L199-K201 VanDerWaalsContact C-N 3.33Å; L199-K201 PolarHBondContact O-N 3.14Å; K201-F205 CarbonylContact O-C 3.4Å; K201-F205 VanDerWaalsContact O-C 3.26Å; K201-F205 VanDerWaalsContact O-CA 3.26Å; K201-F205 WeakPolarHBondContact O-CA 3.31Å; K201-F205 WeakPolarHBondContact O-CB 3.33Å; K201-F205 PolarHBondContact O-N 2.85Å; K201-V209 HydrophobicContact CD-CG2 4.19Å; K201-V209 HydrophobicContact CG-CG2 3.99Å; K201-E212 IonicContact NZ-OE1 3.62Å; K201-E212 PolarHBondContact NZ-OE1 3.32Å; K201-E212 IonicContact NZ-OE2 3.18Å; K201-E212 PolarHBondContact NZ-OE2 3.02Å; K201-E212 VanDerWaalsContact NZ-OE2 3.16Å
202	T	94.1	Very high	93.5	Very high	40 Å²	40	48.2 Å²	48.2	25%	0.245	25%	0.247	C	C	.	.	H	α-helix	trans	-65.9	-42.9	-179.4	-56.2	0	0	0	0	112	Y198 L199 F200 F206	Y198-T202 WeakPolarHBondContact O-CB 3.48Å; Y198-T202 PolarHBondContact O-N 3.35Å; Y198-T202 PolarHBondContact O-OG1 2.76Å; L199-T202 WeakPolarHBondContact O-CB 3.47Å; L199-T202 PolarHBondContact O-N 3.35Å; L199-T202 VanDerWaalsContact O-N 3.11Å; F200-T202 VanDerWaalsContact C-N 3.29Å; F200-T202 PolarHBondContact O-N 3.2Å; T202-F206 HydrophobicContact CG2-CD2 4.26Å; T202-F206 WeakPolarHBondContact O-CB 3.48Å; T202-F206 PolarHBondContact O-N 3.38Å
203	I	93.6	Very high	93.1	Very high	96 Å²	96	46 Å²	46	49%	0.492	23%	0.234	S	C	.	.	H	α-helix	trans	-70.6	-44.3	-179.9	-66.1	167.2	0	0	0	111.1	T75 L199 F200	T75-I203 WeakPolarHBondContact CB-O 3.49Å; T75-I203 WeakPolarHBondContact CG2-O 3.3Å; T75-I203 PolarHBondContact OG1-O 3.14Å; L199-I203 HydrophobicContact CD1-CD1 4.14Å; L199-I203 HydrophobicContact CD1-CG1 4.41Å; L199-I203 HydrophobicContact CG-CD1 3.94Å; L199-I203 WeakPolarHBondContact O-CG1 3.43Å; L199-I203 PolarHBondContact O-N 3.18Å; F200-I203 PolarHBondContact O-N 3.27Å
204	L	91.4	Very high	92.6	Very high	73 Å²	73	45.4 Å²	45.4	38%	0.382	22%	0.221	S	C	.	.	H	α-helix	trans	-87.5	-35.3	-172.9	-63	173.9	0	0	0	113.1	R74 T75 L140 F200	R74-L204 VanDerWaalsContact CA-O 3.3Å; R74-L204 WeakPolarHBondContact CA-O 3.24Å; T75-L204 PolarHBondContact N-O 3.28Å; T75-L204 VanDerWaalsContact N-O 3.15Å; T75-L204 PolarHBondContact OG1-O 3.39Å; L140-L204 HydrophobicContact CD1-CD1 3.66Å; F200-L204 VanDerWaalsContact O-CB 3.3Å; F200-L204 WeakPolarHBondContact O-CB 3.47Å; F200-L204 WeakPolarHBondContact O-CG 3.15Å; F200-L204 PolarHBondContact O-N 3.09Å
205	F	90.7	Very high	92.1	Very high	22 Å²	22	45.1 Å²	45.1	10%	0.096	22%	0.219	C	C	.	.			trans	-130.5	49.6	-171.7	-60.4	-73.6	0	0	0	112.7	F73 L140 L141 K201 E207 A208 V209	F73-F205 HydrophobicContact CB-CD1 3.9Å; F73-F205 WeakPolarHBondContact O-CA 3.43Å; L140-F205 HydrophobicContact CB-CD2 3.89Å; L140-F205 HydrophobicContact CB-CE2 3.95Å; L140-F205 HydrophobicContact CD1-CD2 4.27Å; L140-F205 HydrophobicContact CD1-CE2 4.09Å; L141-F205 HydrophobicContact CD1-CD1 4.34Å; L141-F205 HydrophobicContact CD1-CE1 4.13Å; L141-F205 HydrophobicContact CD1-CZ 4.48Å; L141-F205 HydrophobicContact CD2-CB 3.88Å; L141-F205 HydrophobicContact CD2-CD1 3.77Å; L141-F205 HydrophobicContact CD2-CD2 4.33Å; L141-F205 HydrophobicContact CD2-CE1 4.37Å; L141-F205 HydrophobicContact CD2-CG 3.74Å; L141-F205 HydrophobicContact CG-CD1 4.11Å; L141-F205 HydrophobicContact CG-CD2 4.33Å; L141-F205 HydrophobicContact CG-CE1 4.23Å; L141-F205 HydrophobicContact CG-CE2 4.45Å; L141-F205 HydrophobicContact CG-CG 4.16Å; L141-F205 HydrophobicContact CG-CZ 4.39Å; K201-F205 CarbonylContact O-C 3.4Å; K201-F205 VanDerWaalsContact O-C 3.26Å; K201-F205 VanDerWaalsContact O-CA 3.26Å; K201-F205 WeakPolarHBondContact O-CA 3.31Å; K201-F205 WeakPolarHBondContact O-CB 3.33Å; K201-F205 PolarHBondContact O-N 2.85Å; F205-E207 VanDerWaalsContact C-N 3.26Å; F205-E207 PolarHBondContact O-N 3.01Å; F205-A208 HydrophobicContact CB-CB 4.21Å; F205-A208 VanDerWaalsContact O-CB 3.31Å; F205-A208 WeakPolarHBondContact O-CB 3.49Å; F205-A208 PolarHBondContact O-N 3.34Å; F205-V209 PolarHBondContact O-N 2.89Å
206	F	89.8	Confident	91.4	Very high	99 Å²	99	43.7 Å²	43.7	43%	0.434	21%	0.209	S	C	.	.	H	α-helix	trans	-55.2	-35.5	-178.1	-174	-103.2	0	0	0	114.3	T75 T202 A208 V209 R210	T75-F206 HydrophobicContact CG2-CB 3.05Å; T75-F206 HydrophobicContact CG2-CG 4.23Å; T202-F206 HydrophobicContact CG2-CD2 4.26Å; T202-F206 WeakPolarHBondContact O-CB 3.48Å; T202-F206 PolarHBondContact O-N 3.38Å; F206-A208 PolarHBondContact O-N 2.97Å; F206-V209 PolarHBondContact O-N 3.36Å; F206-V209 VanDerWaalsContact O-N 3.17Å; F206-R210 WeakPolarHBondContact O-CB 3.47Å; F206-R210 PolarHBondContact O-N 2.91Å
207	E	86.3	Confident	90.7	Very high	44 Å²	44	39.8 Å²	39.8	21%	0.206	19%	0.189	C	C	.	.	H	α-helix	trans	-65.5	-30.3	178.3	-72.3	-60.4	153.5	0	0	111.8	F73 F205 R210 R211	F73-E207 HydrophobicContact CD1-CB 4.22Å; F205-E207 VanDerWaalsContact C-N 3.26Å; F205-E207 PolarHBondContact O-N 3.01Å; E207-R210 PolarHBondContact O-N 3.29Å; E207-R210 IonicContact OE1-NH1 2.74Å; E207-R210 PolarHBondContact OE1-NH1 2.84Å; E207-R210 VanDerWaalsContact OE2-CD 3.27Å; E207-R210 WeakPolarHBondContact OE2-CD 3.37Å; E207-R210 IonicContact OE2-NH1 3.19Å; E207-R210 PolarHBondContact OE2-NH1 3.02Å; E207-R211 WeakPolarHBondContact O-CG 3.26Å; E207-R211 PolarHBondContact O-N 3.34Å
208	A	87.9	Confident	90.3	Very high	0 Å²	0	38.4 Å²	38.4	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-67	-45.9	171.9	0	0	0	0	0	111	F73 L141 F205 F206 R210 R211 E212 I462	F73-A208 HydrophobicContact CD1-CB 4.05Å; L141-A208 HydrophobicContact CD2-CB 3.74Å; F205-A208 HydrophobicContact CB-CB 4.21Å; F205-A208 VanDerWaalsContact O-CB 3.31Å; F205-A208 WeakPolarHBondContact O-CB 3.49Å; F205-A208 PolarHBondContact O-N 3.34Å; F206-A208 PolarHBondContact O-N 2.97Å; A208-R210 VanDerWaalsContact C-N 3.3Å; A208-R210 PolarHBondContact O-N 2.8Å; A208-R211 WeakPolarHBondContact O-CB 3.48Å; A208-R211 PolarHBondContact O-N 3.12Å; A208-R211 VanDerWaalsContact O-N 3.13Å; A208-E212 PolarHBondContact O-N 3.06Å; A208-I462 HydrophobicContact CB-CD1 4.21Å
209	V	92.3	Very high	90	Very high	11 Å²	11	38.1 Å²	38.1	7%	0.067	18%	0.18	C	C	.	.	H	α-helix	trans	-61.5	-39.1	175.4	175.8	0	0	0	0	111.4	Y198 K201 F205 F206 R211 E212 F213 F222	Y198-V209 HydrophobicContact CE1-CG1 4.43Å; K201-V209 HydrophobicContact CD-CG2 4.19Å; K201-V209 HydrophobicContact CG-CG2 3.99Å; F205-V209 PolarHBondContact O-N 2.89Å; F206-V209 PolarHBondContact O-N 3.36Å; F206-V209 VanDerWaalsContact O-N 3.17Å; V209-R211 VanDerWaalsContact C-N 3.3Å; V209-R211 PolarHBondContact O-N 3.47Å; V209-E212 WeakPolarHBondContact O-CB 3.48Å; V209-E212 PolarHBondContact O-N 3.49Å; V209-F213 WeakPolarHBondContact O-CB 3.39Å; V209-F213 PolarHBondContact O-N 3.42Å; V209-F222 HydrophobicContact CG1-CE1 3.97Å; V209-F222 HydrophobicContact CG1-CZ 4.06Å
210	R	89.5	Confident	89.8	Confident	98 Å²	98	33.3 Å²	33.3	37%	0.37	16%	0.155	S	C	.	.	H	α-helix	trans	-62.2	-37.5	175.4	-169.2	-176.3	-171.8	-170.7	-1.2	111.9	F206 E207 A208 F213 R214	F206-R210 WeakPolarHBondContact O-CB 3.47Å; F206-R210 PolarHBondContact O-N 2.91Å; E207-R210 PolarHBondContact O-N 3.29Å; E207-R210 IonicContact OE1-NH1 2.74Å; E207-R210 PolarHBondContact OE1-NH1 2.84Å; E207-R210 VanDerWaalsContact OE2-CD 3.27Å; E207-R210 WeakPolarHBondContact OE2-CD 3.37Å; E207-R210 IonicContact OE2-NH1 3.19Å; E207-R210 PolarHBondContact OE2-NH1 3.02Å; A208-R210 VanDerWaalsContact C-N 3.3Å; A208-R210 PolarHBondContact O-N 2.8Å; R210-F213 PolarHBondContact O-N 3.05Å; R210-R214 VanDerWaalsContact NH2-NH2 3.19Å; R210-R214 WeakPolarHBondContact O-CG 3.44Å; R210-R214 PolarHBondContact O-N 2.77Å; R210-R214 VanDerWaalsContact O-N 3.09Å
211	R	87.1	Confident	89.6	Confident	2 Å²	2	29 Å²	29	1%	0.008	14%	0.135	C	C	.	.	H	α-helix	trans	-69.6	-40.8	173.5	-74.3	-175.8	177.1	-146.1	-20.1	112.2	I102 L106 Y111 E207 A208 V209 F213 R214 H215 I462 I464	I102-R211 VanDerWaalsContact CG2-NH2 3.34Å; I102-R211 PolarHBondContact O-NH2 3Å; L106-R211 HydrophobicContact CD1-CG 4.49Å; Y111-R211 PolarHBondContact OH-O 2.89Å; E207-R211 WeakPolarHBondContact O-CG 3.26Å; E207-R211 PolarHBondContact O-N 3.34Å; A208-R211 WeakPolarHBondContact O-CB 3.48Å; A208-R211 PolarHBondContact O-N 3.12Å; A208-R211 VanDerWaalsContact O-N 3.13Å; V209-R211 VanDerWaalsContact C-N 3.3Å; V209-R211 PolarHBondContact O-N 3.47Å; R211-F213 VanDerWaalsContact C-N 3.27Å; R211-F213 PolarHBondContact O-N 3.15Å; R211-R214 PolarHBondContact O-N 2.84Å; R211-H215 PolarHBondContact O-N 3.36Å; R211-I462 WeakPolarHBondContact CD-O 3.47Å; R211-I462 PolarHBondContact NH1-O 2.72Å; R211-I464 PolarHBondContact NH1-O 3.45Å
212	E	90.8	Very high	89.7	Confident	0 Å²	0	30.5 Å²	30.5	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-58.8	-41	172	-69.3	-175.7	139.4	0	0	111.7	P144 I145 Y198 K201 A208 V209 R214 H215 R218 F222 I462	P144-E212 WeakPolarHBondContact CA-OE1 3.39Å; I145-E212 PolarHBondContact N-OE1 3.36Å; Y198-E212 WeakPolarHBondContact CE2-OE2 3.39Å; Y198-E212 PolarHBondContact OH-OE2 3.45Å; K201-E212 IonicContact NZ-OE1 3.62Å; K201-E212 PolarHBondContact NZ-OE1 3.32Å; K201-E212 IonicContact NZ-OE2 3.18Å; K201-E212 PolarHBondContact NZ-OE2 3.02Å; K201-E212 VanDerWaalsContact NZ-OE2 3.16Å; A208-E212 PolarHBondContact O-N 3.06Å; V209-E212 WeakPolarHBondContact O-CB 3.48Å; V209-E212 PolarHBondContact O-N 3.49Å; E212-R214 VanDerWaalsContact C-N 3.26Å; E212-R214 PolarHBondContact O-N 3.41Å; E212-H215 VanDerWaalsContact O-CB 3.26Å; E212-H215 WeakPolarHBondContact O-CB 3.21Å; E212-H215 PolarHBondContact O-N 3.39Å; E212-R218 IonicContact OE1-NH1 3.91Å; E212-F222 HydrophobicContact CB-CE2 4.15Å; E212-F222 HydrophobicContact CB-CZ 4.15Å; E212-I462 HydrophobicContact CG-CG2 4.02Å
213	F	90.9	Very high	89.8	Confident	40 Å²	40	28.7 Å²	28.7	18%	0.175	13%	0.131	C	C	.	.	H	α-helix	trans	-67.4	-27.5	176.5	-166.8	-83.8	0	0	0	112.8	V209 R210 R211 V219 F222 L259 K262 R273	V209-F213 WeakPolarHBondContact O-CB 3.39Å; V209-F213 PolarHBondContact O-N 3.42Å; R210-F213 PolarHBondContact O-N 3.05Å; R211-F213 VanDerWaalsContact C-N 3.27Å; R211-F213 PolarHBondContact O-N 3.15Å; F213-V219 HydrophobicContact CD1-CG2 4.46Å; F213-V219 HydrophobicContact CD2-CG2 4.3Å; F213-V219 HydrophobicContact CE1-CG2 4.21Å; F213-V219 HydrophobicContact CE2-CG2 4.11Å; F213-V219 HydrophobicContact CG-CG2 4.47Å; F213-V219 HydrophobicContact CZ-CG2 4.05Å; F213-V219 WeakPolarHBondContact O-CG2 3.37Å; F213-F222 HydrophobicContact CB-CE1 4.44Å; F213-F222 HydrophobicContact CB-CE2 3.94Å; F213-F222 HydrophobicContact CB-CZ 3.8Å; F213-F222 AromaticContact CD2-CD1 3.84Å; F213-F222 HydrophobicContact CD2-CD1 3.84Å; F213-F222 AromaticContact CD2-CD2 3.87Å; F213-F222 HydrophobicContact CD2-CD2 3.87Å; F213-F222 AromaticContact CD2-CE1 3.9Å; F213-F222 HydrophobicContact CD2-CE1 3.9Å; F213-F222 AromaticContact CD2-CE2 3.92Å; F213-F222 HydrophobicContact CD2-CE2 3.92Å; F213-F222 AromaticContact CD2-CG 3.82Å; F213-F222 HydrophobicContact CD2-CG 3.82Å; F213-F222 AromaticContact CD2-CZ 3.93Å; F213-F222 HydrophobicContact CD2-CZ 3.93Å; F213-F222 HydrophobicContact CE2-CD1 4.41Å; F213-F222 HydrophobicContact CE2-CG 4.23Å; F213-F222 HydrophobicContact CG-CE2 4.4Å; F213-F222 HydrophobicContact CG-CZ 4.39Å; F213-L259 HydrophobicContact CE2-CD2 4.13Å; F213-L259 HydrophobicContact CZ-CD2 4.49Å; F213-K262 HydrophobicContact CE1-CD 4.14Å; F213-K262 VanDerWaalsContact CE1-CE 3.41Å; F213-K262 HydrophobicContact CZ-CD 3.88Å; F213-R273 PolarHBondContact O-NH2 3.3Å; F213-R273 VanDerWaalsContact O-NH2 3.12Å
214	R	86.7	Confident	89.9	Confident	38 Å²	38	24.1 Å²	24.1	14%	0.143	11%	0.107	C	C	.	.	H	α-helix	trans	-79.4	-21.2	175.1	-74.9	173.1	-177.2	167.2	-5.8	113	Y111 R210 R211 E212 R273	Y111-R214 HydrophobicContact CE2-CB 4.18Å; R210-R214 VanDerWaalsContact NH2-NH2 3.19Å; R210-R214 WeakPolarHBondContact O-CG 3.44Å; R210-R214 PolarHBondContact O-N 2.77Å; R210-R214 VanDerWaalsContact O-N 3.09Å; R211-R214 PolarHBondContact O-N 2.84Å; E212-R214 VanDerWaalsContact C-N 3.26Å; E212-R214 PolarHBondContact O-N 3.41Å; R214-R273 PolarHBondContact O-NH2 3.11Å
215	H	85.1	Confident	90.2	Very high	0 Å²	0	21.9 Å²	21.9	0%	0	10%	0.098	C	C	.	.	S	Bend	trans	-65.8	130.7	179.3	-167.2	-99.1	0	0	0	111.7	Y111 E119 R211 E212 I217 R218 V219 V461	Y111-H215 AromaticContact CD1-CD2 3.4Å; Y111-H215 VanDerWaalsContact CD1-CD2 3.4Å; Y111-H215 WeakPolarHBondContact CD1-CD2 3.39Å; Y111-H215 AromaticContact CE1-CD2 3.77Å; Y111-H215 AromaticContact CG-CD2 3.85Å; E119-H215 PolarHBondContact O-CE1 2.94Å; R211-H215 PolarHBondContact O-N 3.36Å; E212-H215 VanDerWaalsContact O-CB 3.26Å; E212-H215 WeakPolarHBondContact O-CB 3.21Å; E212-H215 PolarHBondContact O-N 3.39Å; H215-I217 PolarHBondContact ND1-N 3.1Å; H215-I217 PolarHBondContact O-N 3.34Å; H215-R218 HydrophobicContact CB-CB 4Å; H215-R218 HydrophobicContact CB-CG 4.45Å; H215-R218 PolarHBondContact ND1-N 2.72Å; H215-R218 VanDerWaalsContact ND1-N 3.17Å; H215-V219 VanDerWaalsContact O-CB 3.32Å; H215-V219 WeakPolarHBondContact O-CB 3.29Å; H215-V219 WeakPolarHBondContact O-CG1 3.35Å; H215-V219 PolarHBondContact O-N 3.06Å; H215-V461 WeakPolarHBondContact CD2-CG1 3.35Å
216	P	83.3	Confident	90.5	Very high	5 Å²	5	22.3 Å²	22.3	3%	0.032	10%	0.1	C	C	.	.	T	Hydrogen-bonded Turn	trans	-64.7	-24.4	-173.6	24.7	-34.3	0	0	0	114.4	F112 L120 V278	F112-P216 HydrophobicContact CE2-CB 4.06Å; F112-P216 HydrophobicContact CE2-CG 3.9Å; F112-P216 HydrophobicContact CZ-CB 4.02Å; F112-P216 HydrophobicContact CZ-CG 3.91Å; L120-P216 HydrophobicContact CD1-CG 3.84Å; P216-V278 HydrophobicContact CB-CB 4.46Å; P216-V278 HydrophobicContact CB-CG1 4.18Å
217	I	83.1	Confident	90.8	Very high	9 Å²	9	17.6 Å²	17.6	5%	0.046	8%	0.08	C	C	.	.	T	Hydrogen-bonded Turn	trans	-98.2	-45.9	179.5	-60.8	176	0	0	0	111.3	P118 L120 H215 V219 N220 T282	P118-I217 VanDerWaalsContact O-CD1 3.29Å; P118-I217 WeakPolarHBondContact O-CD1 3.12Å; L120-I217 HydrophobicContact CB-CD1 4.07Å; L120-I217 HydrophobicContact CD1-CD1 3.63Å; L120-I217 HydrophobicContact CD1-CG1 4.11Å; L120-I217 HydrophobicContact CG-CD1 3.7Å; H215-I217 PolarHBondContact ND1-N 3.1Å; H215-I217 PolarHBondContact O-N 3.34Å; I217-V219 VanDerWaalsContact C-N 3.27Å; I217-V219 PolarHBondContact O-N 2.89Å; I217-N220 WeakPolarHBondContact O-CB 3.28Å; I217-N220 PolarHBondContact O-N 2.86Å; I217-N220 PolarHBondContact O-ND2 3.46Å; I217-T282 HydrophobicContact CG2-CG2 3.96Å
218	R	88.6	Confident	91.3	Very high	5 Å²	5	15.5 Å²	15.5	2%	0.019	7%	0.07	C	C	.	.	G	3₁₀ helix	trans	-73.1	-22.7	-172.4	-67	178.3	177	-176.1	2.8	112.4	E121 I145 T146 E212 H215 N220 F221 D459	E121-R218 IonicContact OE1-CZ 2.7Å; E121-R218 IonicContact OE1-NE 2.85Å; E121-R218 IonicContact OE1-NH2 3.14Å; E121-R218 PolarHBondContact OE1-NH2 2.91Å; I145-R218 HydrophobicContact CG2-CB 3.95Å; T146-R218 HydrophobicContact CG2-CG 4.2Å; E212-R218 IonicContact OE1-NH1 3.91Å; H215-R218 HydrophobicContact CB-CB 4Å; H215-R218 HydrophobicContact CB-CG 4.45Å; H215-R218 PolarHBondContact ND1-N 2.72Å; H215-R218 VanDerWaalsContact ND1-N 3.17Å; R218-N220 PolarHBondContact O-N 2.78Å; R218-N220 VanDerWaalsContact O-N 3.16Å; R218-F221 PolarHBondContact O-N 2.81Å; R218-D459 IonicContact CZ-OD1 3.27Å; R218-D459 IonicContact CZ-OD2 2.97Å; R218-D459 IonicContact NH1-OD1 3.95Å; R218-D459 PolarHBondContact NH1-OD1 3.23Å; R218-D459 IonicContact NH1-OD2 2.78Å; R218-D459 PolarHBondContact NH1-OD2 3.16Å; R218-D459 IonicContact NH2-OD1 2.74Å; R218-D459 PolarHBondContact NH2-OD1 3.39Å; R218-D459 IonicContact NH2-OD2 2.74Å
219	V	91.2	Very high	91.8	Very high	7 Å²	7	18.5 Å²	18.5	4%	0.042	9%	0.085	C	C	.	.	G	3₁₀ helix	trans	-54.3	-32.5	172	71	0	0	0	0	112.2	F213 H215 I217 F221 F222 I263	F213-V219 HydrophobicContact CD1-CG2 4.46Å; F213-V219 HydrophobicContact CD2-CG2 4.3Å; F213-V219 HydrophobicContact CE1-CG2 4.21Å; F213-V219 HydrophobicContact CE2-CG2 4.11Å; F213-V219 HydrophobicContact CG-CG2 4.47Å; F213-V219 HydrophobicContact CZ-CG2 4.05Å; F213-V219 WeakPolarHBondContact O-CG2 3.37Å; H215-V219 VanDerWaalsContact O-CB 3.32Å; H215-V219 WeakPolarHBondContact O-CB 3.29Å; H215-V219 WeakPolarHBondContact O-CG1 3.35Å; H215-V219 PolarHBondContact O-N 3.06Å; I217-V219 VanDerWaalsContact C-N 3.27Å; I217-V219 PolarHBondContact O-N 2.89Å; V219-F221 VanDerWaalsContact C-N 3.28Å; V219-F221 PolarHBondContact O-N 3.42Å; V219-F222 WeakPolarHBondContact O-CB 3.38Å; V219-F222 PolarHBondContact O-N 3.11Å; V219-I263 HydrophobicContact CG1-CD1 4.29Å; V219-I263 HydrophobicContact CG2-CD1 3.62Å
220	N	91.2	Very high	92.1	Very high	1 Å²	1	18 Å²	18	1%	0.005	8%	0.082	C	C	.	.	G	3₁₀ helix	trans	-67.9	-27.9	178.4	-62.2	-46.9	0	0	0	112.6	I217 R218 F222 F223 T282 N283 L285	I217-N220 WeakPolarHBondContact O-CB 3.28Å; I217-N220 PolarHBondContact O-N 2.86Å; I217-N220 PolarHBondContact O-ND2 3.46Å; R218-N220 PolarHBondContact O-N 2.78Å; R218-N220 VanDerWaalsContact O-N 3.16Å; N220-F222 PolarHBondContact O-N 3.29Å; N220-F223 WeakPolarHBondContact O-CD2 3.31Å; N220-F223 PolarHBondContact O-N 3.15Å; N220-T282 PolarHBondContact ND2-OG1 2.81Å; N220-N283 VanDerWaalsContact CG-ND2 3.29Å; N220-N283 PolarHBondContact ND2-ND2 3.49Å; N220-N283 PolarHBondContact OD1-ND2 2.79Å; N220-L285 VanDerWaalsContact O-CD2 3.28Å; N220-L285 WeakPolarHBondContact O-CD2 3.42Å
221	F	93.5	Very high	92.4	Very high	18 Å²	18	13.5 Å²	13.5	8%	0.079	7%	0.066	C	C	.	.	G	3₁₀ helix	trans	-75.7	-8.6	178.4	-75.3	-96.5	0	0	0	113.3	I145 T146 R218 V219 F223 A224 P225 T282 L285	I145-F221 HydrophobicContact CG1-CB 3.94Å; I145-F221 HydrophobicContact CG2-CB 4.01Å; T146-F221 HydrophobicContact CG2-CD1 4.2Å; T146-F221 HydrophobicContact CG2-CD2 3.77Å; T146-F221 HydrophobicContact CG2-CE1 4.23Å; T146-F221 HydrophobicContact CG2-CE2 3.8Å; T146-F221 HydrophobicContact CG2-CG 3.95Å; T146-F221 HydrophobicContact CG2-CZ 4.03Å; R218-F221 PolarHBondContact O-N 2.81Å; V219-F221 VanDerWaalsContact C-N 3.28Å; V219-F221 PolarHBondContact O-N 3.42Å; F221-F223 PolarHBondContact O-N 3.39Å; F221-A224 WeakPolarHBondContact O-CB 3.48Å; F221-A224 PolarHBondContact O-N 2.95Å; F221-P225 WeakPolarHBondContact O-CD 3.14Å; F221-T282 HydrophobicContact CE2-CG2 3.92Å; F221-T282 HydrophobicContact CZ-CG2 4.4Å; F221-L285 HydrophobicContact CD1-CD2 4.09Å; F221-L285 HydrophobicContact CG-CD2 4.24Å
222	F	95.8	Very high	92.9	Very high	33 Å²	33	14.5 Å²	14.5	15%	0.145	7%	0.071	C	C	.	.	G	3₁₀ helix	trans	-67.7	-14.7	171.4	-77.4	-96.4	0	0	0	113.2	I145 V209 E212 F213 V219 N220 P225	I145-F222 HydrophobicContact CG1-CD2 4.23Å; I145-F222 HydrophobicContact CG1-CE2 4.28Å; I145-F222 HydrophobicContact CG1-CG 4.45Å; I145-F222 HydrophobicContact CG2-CE2 4.27Å; V209-F222 HydrophobicContact CG1-CE1 3.97Å; V209-F222 HydrophobicContact CG1-CZ 4.06Å; E212-F222 HydrophobicContact CB-CE2 4.15Å; E212-F222 HydrophobicContact CB-CZ 4.15Å; F213-F222 HydrophobicContact CB-CE1 4.44Å; F213-F222 HydrophobicContact CB-CE2 3.94Å; F213-F222 HydrophobicContact CB-CZ 3.8Å; F213-F222 AromaticContact CD2-CD1 3.84Å; F213-F222 HydrophobicContact CD2-CD1 3.84Å; F213-F222 AromaticContact CD2-CD2 3.87Å; F213-F222 HydrophobicContact CD2-CD2 3.87Å; F213-F222 AromaticContact CD2-CE1 3.9Å; F213-F222 HydrophobicContact CD2-CE1 3.9Å; F213-F222 AromaticContact CD2-CE2 3.92Å; F213-F222 HydrophobicContact CD2-CE2 3.92Å; F213-F222 AromaticContact CD2-CG 3.82Å; F213-F222 HydrophobicContact CD2-CG 3.82Å; F213-F222 AromaticContact CD2-CZ 3.93Å; F213-F222 HydrophobicContact CD2-CZ 3.93Å; F213-F222 HydrophobicContact CE2-CD1 4.41Å; F213-F222 HydrophobicContact CE2-CG 4.23Å; F213-F222 HydrophobicContact CG-CE2 4.4Å; F213-F222 HydrophobicContact CG-CZ 4.39Å; V219-F222 WeakPolarHBondContact O-CB 3.38Å; V219-F222 PolarHBondContact O-N 3.11Å; N220-F222 PolarHBondContact O-N 3.29Å; F222-P225 WeakPolarHBondContact O-CD 3.43Å
223	F	96.3	Very high	93.1	Very high	1 Å²	1	15 Å²	15	0%	0.004	8%	0.075	C	C	.	.	G	3₁₀ helix	trans	-76.3	-26.7	167.4	-68.1	-84.5	0	0	0	112.4	N220 F221 P225 L226 I227 I256 L259 E260 I263 L285	N220-F223 WeakPolarHBondContact O-CD2 3.31Å; N220-F223 PolarHBondContact O-N 3.15Å; F221-F223 PolarHBondContact O-N 3.39Å; F223-P225 VanDerWaalsContact C-CD 3.47Å; F223-L226 PolarHBondContact O-N 3.18Å; F223-I227 HydrophobicContact CB-CD1 3.81Å; F223-I227 HydrophobicContact CB-CG1 4.47Å; F223-I227 VanDerWaalsContact O-CG1 3.3Å; F223-I227 WeakPolarHBondContact O-CG1 3.34Å; F223-I227 PolarHBondContact O-N 3.34Å; F223-I256 HydrophobicContact CD1-CG2 4.36Å; F223-I256 HydrophobicContact CE1-CG2 4.33Å; F223-L259 HydrophobicContact CD1-CB 4.14Å; F223-L259 HydrophobicContact CD1-CD1 4.09Å; F223-L259 HydrophobicContact CE1-CB 3.37Å; F223-L259 HydrophobicContact CE1-CD1 4.16Å; F223-L259 HydrophobicContact CE1-CG 4.42Å; F223-L259 HydrophobicContact CE2-CB 4.3Å; F223-L259 HydrophobicContact CG-CD1 4.49Å; F223-L259 HydrophobicContact CZ-CB 3.48Å; F223-L259 VanDerWaalsContact CZ-CB 3.48Å; F223-E260 HydrophobicContact CE1-CG 3.87Å; F223-E260 HydrophobicContact CZ-CG 4.13Å; F223-I263 HydrophobicContact CE2-CG1 4.13Å; F223-I263 HydrophobicContact CZ-CG1 4.29Å; F223-L285 HydrophobicContact CB-CG 4.42Å
224	A	96.2	Very high	93.3	Very high	0 Å²	0	14.2 Å²	14.2	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-57.9	-39.6	-171.4	0	0	0	0	0	115	Y148 L152 F221 L226 I227 S228 L285	Y148-A224 VanDerWaalsContact CB-CB 3.48Å; Y148-A224 HydrophobicContact CG-CB 4.29Å; L152-A224 HydrophobicContact CD1-CB 3.96Å; L152-A224 HydrophobicContact CG-CB 4.46Å; F221-A224 WeakPolarHBondContact O-CB 3.48Å; F221-A224 PolarHBondContact O-N 2.95Å; A224-L226 PolarHBondContact O-N 3.47Å; A224-I227 PolarHBondContact O-N 2.74Å; A224-S228 VanDerWaalsContact O-CB 3.32Å; A224-S228 WeakPolarHBondContact O-CB 3.24Å; A224-S228 PolarHBondContact O-N 2.91Å; A224-S228 PolarHBondContact O-OG 3.4Å; A224-L285 HydrophobicContact CB-CD2 4.02Å
225	P	97.2	Very high	93.6	Very high	27 Å²	27	12.4 Å²	12.4	18%	0.175	7%	0.066	C	C	.	.	H	α-helix	trans	-60.5	-46.2	177	-21.8	31.9	0	0	0	112.3	I145 Y148 F221 F222 F223 S228 I229	I145-P225 HydrophobicContact CD1-CG 4.29Å; Y148-P225 HydrophobicContact CD1-CB 4.03Å; Y148-P225 HydrophobicContact CD1-CG 3.95Å; Y148-P225 HydrophobicContact CD2-CG 4.02Å; Y148-P225 HydrophobicContact CE1-CB 3.55Å; Y148-P225 HydrophobicContact CE1-CG 3.71Å; Y148-P225 HydrophobicContact CE2-CB 4.44Å; Y148-P225 HydrophobicContact CE2-CG 3.77Å; Y148-P225 HydrophobicContact CG-CG 4.08Å; F221-P225 WeakPolarHBondContact O-CD 3.14Å; F222-P225 WeakPolarHBondContact O-CD 3.43Å; F223-P225 VanDerWaalsContact C-CD 3.47Å; P225-S228 WeakPolarHBondContact O-CB 3.32Å; P225-S228 PolarHBondContact O-N 2.92Å; P225-I229 WeakPolarHBondContact O-CG1 3.08Å; P225-I229 PolarHBondContact O-N 2.85Å; P225-I229 VanDerWaalsContact O-N 3.09Å
226	L	97.5	Very high	94	Very high	30 Å²	30	13.1 Å²	13.1	16%	0.157	7%	0.069	C	C	.	.	H	α-helix	trans	-67.1	-43.5	-179.6	-63.8	165	0	0	0	110.8	F223 A224 S228 I229 L230 P255 I256 L259	F223-L226 PolarHBondContact O-N 3.18Å; A224-L226 PolarHBondContact O-N 3.47Å; L226-S228 VanDerWaalsContact C-N 3.3Å; L226-S228 PolarHBondContact O-N 3.44Å; L226-I229 PolarHBondContact O-N 2.65Å; L226-I229 VanDerWaalsContact O-N 3.16Å; L226-L230 WeakPolarHBondContact O-CG 3.39Å; L226-L230 PolarHBondContact O-N 3.16Å; L226-P255 HydrophobicContact CD1-CB 3.69Å; L226-P255 HydrophobicContact CD2-CB 4.25Å; L226-P255 HydrophobicContact CD2-CG 4.46Å; L226-I256 HydrophobicContact CB-CD1 4.04Å; L226-I256 HydrophobicContact CB-CG1 3.91Å; L226-I256 HydrophobicContact CD1-CG1 3.72Å; L226-I256 HydrophobicContact CG-CG1 4.41Å; L226-L259 HydrophobicContact CD1-CD1 4.08Å
227	I	96.7	Very high	94.3	Very high	0 Å²	0	12.9 Å²	12.9	0%	0	7%	0.068	C	C	.	.	H	α-helix	trans	-62.8	-38.5	175.7	-61	170.6	0	0	0	111.1	L152 F223 A224 I229 L230 F231 L285	L152-I227 HydrophobicContact CD2-CB 3.86Å; L152-I227 HydrophobicContact CD2-CG2 3.53Å; F223-I227 HydrophobicContact CB-CD1 3.81Å; F223-I227 HydrophobicContact CB-CG1 4.47Å; F223-I227 VanDerWaalsContact O-CG1 3.3Å; F223-I227 WeakPolarHBondContact O-CG1 3.34Å; F223-I227 PolarHBondContact O-N 3.34Å; A224-I227 PolarHBondContact O-N 2.74Å; I227-I229 VanDerWaalsContact C-N 3.3Å; I227-I229 PolarHBondContact O-N 2.74Å; I227-L230 WeakPolarHBondContact O-CB 3.27Å; I227-L230 PolarHBondContact O-N 3.15Å; I227-F231 HydrophobicContact CG2-CD1 4.29Å; I227-F231 HydrophobicContact CG2-CD2 4.37Å; I227-F231 HydrophobicContact CG2-CE1 3.93Å; I227-F231 HydrophobicContact CG2-CE2 3.99Å; I227-F231 HydrophobicContact CG2-CZ 3.73Å; I227-F231 WeakPolarHBondContact O-CG 3.4Å; I227-F231 PolarHBondContact O-N 3.43Å; I227-L285 HydrophobicContact CD1-CD1 3.64Å; I227-L285 HydrophobicContact CD1-CG 3.95Å; I227-L285 WeakPolarHBondContact CD1-O 3.33Å
228	S	97.5	Very high	94.2	Very high	1 Å²	1	17.3 Å²	17.3	1%	0.007	9%	0.088	C	C	.	.	H	α-helix	trans	-63.6	-37	176.1	-58.4	0	0	0	0	111.7	C151 L152 A224 P225 L226 F231 L232	C151-S228 WeakPolarHBondContact CB-OG 3.19Å; L152-S228 WeakPolarHBondContact CD2-OG 3.42Å; A224-S228 VanDerWaalsContact O-CB 3.32Å; A224-S228 WeakPolarHBondContact O-CB 3.24Å; A224-S228 PolarHBondContact O-N 2.91Å; A224-S228 PolarHBondContact O-OG 3.4Å; P225-S228 WeakPolarHBondContact O-CB 3.32Å; P225-S228 PolarHBondContact O-N 2.92Å; L226-S228 VanDerWaalsContact C-N 3.3Å; L226-S228 PolarHBondContact O-N 3.44Å; S228-F231 PolarHBondContact O-N 3.24Å; S228-L232 WeakPolarHBondContact O-CB 3.16Å; S228-L232 PolarHBondContact O-N 2.73Å
229	I	97.6	Very high	93.8	Very high	62 Å²	62	21.1 Å²	21.1	32%	0.318	12%	0.116	S	C	.	.	H	α-helix	trans	-69	-40.3	173.9	-60.8	162.9	0	0	0	110.8	L191 P225 L226 I227 F231 L232 A233 L252	L191-I229 HydrophobicContact CD2-CG1 3.93Å; P225-I229 WeakPolarHBondContact O-CG1 3.08Å; P225-I229 PolarHBondContact O-N 2.85Å; P225-I229 VanDerWaalsContact O-N 3.09Å; L226-I229 PolarHBondContact O-N 2.65Å; L226-I229 VanDerWaalsContact O-N 3.16Å; I227-I229 VanDerWaalsContact C-N 3.3Å; I227-I229 PolarHBondContact O-N 2.74Å; I229-F231 VanDerWaalsContact C-N 3.33Å; I229-F231 PolarHBondContact O-N 3.21Å; I229-L232 WeakPolarHBondContact O-CB 3.33Å; I229-L232 PolarHBondContact O-N 2.78Å; I229-A233 PolarHBondContact O-N 3.15Å; I229-L252 HydrophobicContact CB-CD2 4.15Å; I229-L252 HydrophobicContact CD1-CD2 4.41Å; I229-L252 HydrophobicContact CG2-CD1 3.94Å; I229-L252 HydrophobicContact CG2-CD2 3.6Å; I229-L252 HydrophobicContact CG2-CG 4.45Å
230	L	97.4	Very high	93.3	Very high	0 Å²	0	24 Å²	24	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-58.9	-45.1	173.3	-68.3	173.6	0	0	0	111.2	L226 I227 A233 L234 L252 M253 I256 A292 L296	L226-L230 WeakPolarHBondContact O-CG 3.39Å; L226-L230 PolarHBondContact O-N 3.16Å; I227-L230 WeakPolarHBondContact O-CB 3.27Å; I227-L230 PolarHBondContact O-N 3.15Å; L230-A233 PolarHBondContact O-N 2.97Å; L230-L234 WeakPolarHBondContact O-CG 3.3Å; L230-L234 PolarHBondContact O-N 3.28Å; L230-L252 HydrophobicContact CD2-CB 4Å; L230-L252 HydrophobicContact CD2-CD1 3.83Å; L230-M253 HydrophobicContact CD1-SD 4.18Å; L230-M253 HydrophobicContact CD2-SD 4.37Å; L230-I256 HydrophobicContact CD1-CD1 3.68Å; L230-A292 HydrophobicContact CD1-CB 4.24Å; L230-L296 HydrophobicContact CD2-CB 4.42Å; L230-L296 HydrophobicContact CD2-CD2 3.39Å
231	F	97.2	Very high	92.8	Very high	5 Å²	5	27.5 Å²	27.5	2%	0.022	15%	0.148	C	C	.	.	H	α-helix	trans	-65.8	-40.3	177.2	-74.4	-0.3	0	0	0	112.3	L152 S155 I159 I227 S228 I229 A233 L234 G235 V288 A292 F402	L152-F231 HydrophobicContact CD2-CD2 4.15Å; L152-F231 HydrophobicContact CD2-CE2 4.06Å; S155-F231 WeakPolarHBondContact OG-CB 3.44Å; S155-F231 WeakPolarHBondContact OG-CD2 3.16Å; I159-F231 HydrophobicContact CD1-CB 3.76Å; I159-F231 HydrophobicContact CD1-CD1 4.04Å; I159-F231 HydrophobicContact CD1-CG 3.9Å; I159-F231 WeakPolarHBondContact CD1-O 3.42Å; I227-F231 HydrophobicContact CG2-CD1 4.29Å; I227-F231 HydrophobicContact CG2-CD2 4.37Å; I227-F231 HydrophobicContact CG2-CE1 3.93Å; I227-F231 HydrophobicContact CG2-CE2 3.99Å; I227-F231 HydrophobicContact CG2-CZ 3.73Å; I227-F231 WeakPolarHBondContact O-CG 3.4Å; I227-F231 PolarHBondContact O-N 3.43Å; S228-F231 PolarHBondContact O-N 3.24Å; I229-F231 VanDerWaalsContact C-N 3.33Å; I229-F231 PolarHBondContact O-N 3.21Å; F231-A233 VanDerWaalsContact C-N 3.28Å; F231-A233 PolarHBondContact O-N 2.74Å; F231-L234 HydrophobicContact CD1-CD1 4.21Å; F231-L234 PolarHBondContact O-N 2.91Å; F231-G235 PolarHBondContact O-N 2.88Å; F231-V288 HydrophobicContact CZ-CG1 4.25Å; F231-A292 HydrophobicContact CD1-CB 4.3Å; F231-A292 HydrophobicContact CE1-CB 3.62Å; F231-F402 HydrophobicContact CE1-CE2 4.32Å; F231-F402 AromaticContact CE2-CD2 3.48Å; F231-F402 HydrophobicContact CE2-CD2 3.48Å; F231-F402 VanDerWaalsContact CE2-CD2 3.48Å; F231-F402 AromaticContact CE2-CE2 3.33Å; F231-F402 HydrophobicContact CE2-CE2 3.33Å; F231-F402 HydrophobicContact CE2-CG 4.23Å; F231-F402 AromaticContact CE2-CZ 3.96Å; F231-F402 HydrophobicContact CE2-CZ 3.96Å; F231-F402 AromaticContact CZ-CD2 3.87Å; F231-F402 HydrophobicContact CZ-CD2 3.87Å; F231-F402 HydrophobicContact CZ-CE1 4.41Å; F231-F402 AromaticContact CZ-CE2 3.19Å; F231-F402 HydrophobicContact CZ-CE2 3.19Å; F231-F402 AromaticContact CZ-CZ 3.52Å; F231-F402 HydrophobicContact CZ-CZ 3.52Å
232	L	96.2	Very high	92	Very high	23 Å²	23	30.8 Å²	30.8	12%	0.12	17%	0.174	C	C	.	.	H	α-helix	trans	-58.5	-43.1	173.8	-173.5	72	0	0	0	111	W184 L188 L191 S228 I229 G235 I236	W184-L232 HydrophobicContact CD2-CD1 4.39Å; W184-L232 HydrophobicContact CG-CD1 4.49Å; W184-L232 HydrophobicContact CZ2-CD1 4.14Å; W184-L232 HydrophobicContact CZ2-CG 4.29Å; W184-L232 PolarHBondContact NE1-O 3.38Å; L188-L232 HydrophobicContact CB-CD1 4.03Å; L188-L232 HydrophobicContact CD1-CD2 3.63Å; L191-L232 HydrophobicContact CD2-CD2 4.17Å; S228-L232 WeakPolarHBondContact O-CB 3.16Å; S228-L232 PolarHBondContact O-N 2.73Å; I229-L232 WeakPolarHBondContact O-CB 3.33Å; I229-L232 PolarHBondContact O-N 2.78Å; L232-G235 PolarHBondContact O-N 3.34Å; L232-I236 WeakPolarHBondContact O-CG1 3.2Å; L232-I236 PolarHBondContact O-N 2.93Å
233	A	95.7	Very high	91.3	Very high	10 Å²	10	37.3 Å²	37.3	8%	0.083	20%	0.204	C	C	.	.	H	α-helix	trans	-64.9	-43.6	177	0	0	0	0	0	112.6	I229 L230 F231 G235 I236 L296	I229-A233 PolarHBondContact O-N 3.15Å; L230-A233 PolarHBondContact O-N 2.97Å; F231-A233 VanDerWaalsContact C-N 3.28Å; F231-A233 PolarHBondContact O-N 2.74Å; A233-G235 VanDerWaalsContact C-N 3.29Å; A233-G235 PolarHBondContact O-N 2.78Å; A233-I236 PolarHBondContact O-N 3.22Å; A233-L296 HydrophobicContact CB-CD1 3.91Å; A233-L296 HydrophobicContact CB-CD2 3.91Å
234	L	94.8	Very high	90.9	Very high	23 Å²	23	39.3 Å²	39.3	12%	0.12	22%	0.215	C	C	.	.	H	α-helix	trans	-62.1	-37.2	174.9	-73.4	169.6	0	0	0	112.3	I159 K162 L230 F231 I236 L295 L296	I159-L234 HydrophobicContact CD1-CB 3.86Å; I159-L234 HydrophobicContact CD1-CD1 4.39Å; I159-L234 HydrophobicContact CG1-CB 4.15Å; K162-L234 PolarHBondContact NZ-O 3.48Å; L230-L234 WeakPolarHBondContact O-CG 3.3Å; L230-L234 PolarHBondContact O-N 3.28Å; F231-L234 HydrophobicContact CD1-CD1 4.21Å; F231-L234 PolarHBondContact O-N 2.91Å; L234-I236 VanDerWaalsContact C-N 3.33Å; L234-I236 PolarHBondContact O-N 3.34Å; L234-L295 HydrophobicContact CD1-CD2 3.83Å; L234-L295 HydrophobicContact CD1-CG 4.1Å; L234-L295 HydrophobicContact CD2-CD2 4.33Å; L234-L295 HydrophobicContact CD2-CG 3.91Å; L234-L296 HydrophobicContact CD2-CB 4.01Å; L234-L296 HydrophobicContact CD2-CD1 3.79Å; L234-L296 HydrophobicContact CG-CB 4.2Å; L234-L296 HydrophobicContact CG-CD1 3.98Å
235	G	93.5	Very high	90.7	Very high	1 Å²	1	43.3 Å²	43.3	1%	0.01	24%	0.24	C	C	.	.	H	α-helix	trans	-77	-10.4	-178.2	0	0	0	0	0	115.1	N180 F231 L232 A233 P237	N180-G235 PolarHBondContact OD1-O 3.48Å; F231-G235 PolarHBondContact O-N 2.88Å; L232-G235 PolarHBondContact O-N 3.34Å; A233-G235 VanDerWaalsContact C-N 3.29Å; A233-G235 PolarHBondContact O-N 2.78Å; G235-P237 WeakPolarHBondContact O-CD 2.9Å
236	I	93.1	Very high	90.5	Very high	14 Å²	14	44.3 Å²	44.3	7%	0.072	25%	0.248	C	C	.	.			trans	-52.2	124.2	-175.6	-75.2	167.7	0	0	0	110.9	K162 W184 L232 A233 L234 I241 L244	K162-I236 WeakPolarHBondContact CE-O 3.26Å; K162-I236 PolarHBondContact NZ-O 3.31Å; W184-I236 HydrophobicContact CZ2-CG1 3.71Å; L232-I236 WeakPolarHBondContact O-CG1 3.2Å; L232-I236 PolarHBondContact O-N 2.93Å; A233-I236 PolarHBondContact O-N 3.22Å; L234-I236 VanDerWaalsContact C-N 3.33Å; L234-I236 PolarHBondContact O-N 3.34Å; I236-I241 HydrophobicContact CD1-CD1 4.41Å; I236-I241 HydrophobicContact CG2-CB 4.04Å; I236-L244 HydrophobicContact CD1-CD1 3.94Å; I236-L244 HydrophobicContact CD1-CD2 3.9Å; I236-L244 HydrophobicContact CD1-CG 4.33Å
237	P	89.2	Confident	90.3	Very high	0 Å²	0	47 Å²	47	0%	0	27%	0.266	C	S	.	.			trans	-63.2	137.9	171.7	-21	31.6	0	0	0	111.7	H181 W184 G235 S239 I240	H181-P237 WeakPolarHBondContact CE1-CB 3.31Å; H181-P237 WeakPolarHBondContact NE2-CB 3.28Å; W184-P237 HydrophobicContact CB-CG 4.31Å; W184-P237 HydrophobicContact CG-CG 4.33Å; G235-P237 WeakPolarHBondContact O-CD 2.9Å; P237-S239 PolarHBondContact O-N 3.08Å; P237-I240 HydrophobicContact CB-CD1 4.4Å; P237-I240 HydrophobicContact CB-CG1 4.37Å; P237-I240 HydrophobicContact CG-CD1 4.04Å; P237-I240 PolarHBondContact O-N 2.88Å
238	H	81.7	Confident	90.2	Very high	103 Å²	103	49.7 Å²	49.7	48%	0.477	28%	0.28	S	S	.	.	T	Hydrogen-bonded Turn	trans	-58	-24.4	-176.5	-74.9	-75.2	0	0	0	115
239	S	80.5	Confident	90.1	Very high	85 Å²	85	49.8 Å²	49.8	59%	0.594	28%	0.28	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75.6	-18.9	178.3	50.7	0	0	0	0	114.2	H181 P237	H181-S239 PolarHBondContact CE1-OG 3.15Å; H181-S239 PolarHBondContact NE2-OG 2.88Å; P237-S239 PolarHBondContact O-N 3.08Å
240	I	81.3	Confident	90.1	Very high	68 Å²	68	52.9 Å²	52.9	35%	0.349	29%	0.289	S	S	.	.	T	Hydrogen-bonded Turn	trans	-90.2	-58.1	-178.4	-57.2	-178	0	0	0	110.2	W184 W185 P237	W184-I240 HydrophobicContact CE3-CD1 4.07Å; W184-I240 HydrophobicContact CH2-CD1 4.47Å; W184-I240 HydrophobicContact CZ3-CD1 3.87Å; W185-I240 HydrophobicContact CZ2-CD1 4.41Å; P237-I240 HydrophobicContact CB-CD1 4.4Å; P237-I240 HydrophobicContact CB-CG1 4.37Å; P237-I240 HydrophobicContact CG-CD1 4.04Å; P237-I240 PolarHBondContact O-N 2.88Å
241	I	80.6	Confident	90	Very high	73 Å²	73	60 Å²	60	37%	0.374	32%	0.32	S	S	.	.			trans	-136.6	124	179.6	-69	155.9	0	0	0	108.1	I236 H243 L244	I236-I241 HydrophobicContact CD1-CD1 4.41Å; I236-I241 HydrophobicContact CG2-CB 4.04Å; I241-H243 WeakPolarHBondContact CG2-O 3.14Å; I241-L244 HydrophobicContact CG2-CG 4.13Å
242	S	75.8	Confident	90	Very high	88 Å²	88	60.5 Å²	60.5	62%	0.615	32%	0.323	S	S	*	.	S	Bend	trans	-88.6	-32.8	177.5	-45.4	0	0	0	0	112.6
243	H	82.3	Confident	90	Very high	169 Å²	169	59.5 Å²	59.5	78%	0.782	32%	0.317	S	S	*	.			trans	-134.7	122.2	-178.8	-61.4	-73.7	0	0	0	110.7	I241	I241-H243 WeakPolarHBondContact CG2-O 3.14Å
244	L	87.3	Confident	90.1	Very high	44 Å²	44	61 Å²	61	23%	0.23	33%	0.33	C	S	.	.			trans	-89.9	141.9	170.2	-74	133.9	0	0	0	109.2	I236 I241 S246 L248 M300	I236-L244 HydrophobicContact CD1-CD1 3.94Å; I236-L244 HydrophobicContact CD1-CD2 3.9Å; I236-L244 HydrophobicContact CD1-CG 4.33Å; I241-L244 HydrophobicContact CG2-CG 4.13Å; L244-S246 PolarHBondContact O-N 3.49Å; L244-L248 HydrophobicContact CD2-CD2 3.65Å; L244-M300 HydrophobicContact CB-CE 3.49Å; L244-M300 VanDerWaalsContact CB-CE 3.49Å; L244-M300 HydrophobicContact CB-SD 4.41Å; L244-M300 HydrophobicContact CD1-CE 3.99Å; L244-M300 HydrophobicContact CG-CE 4.23Å
245	P	92.5	Very high	90.2	Very high	83 Å²	83	62.2 Å²	62.2	54%	0.539	34%	0.339	S	S	.	.			trans	-64.5	129.1	176.1	26.8	-33	0	0	0	109.9	T247 L248	P245-T247 PolarHBondContact O-N 2.9Å; P245-T247 VanDerWaalsContact O-N 3.07Å; P245-L248 HydrophobicContact CG-CB 4.28Å; P245-L248 VanDerWaalsContact O-CB 3.25Å; P245-L248 WeakPolarHBondContact O-CB 3.15Å; P245-L248 PolarHBondContact O-N 3.21Å
246	S	92.4	Very high	90.4	Very high	49 Å²	49	62.2 Å²	62.2	34%	0.343	34%	0.339	S	S	.	.	H	α-helix	trans	-59	-24.7	-179.8	-46.3	0	0	0	0	112.9	L244 L248 W249 Y250	L244-S246 PolarHBondContact O-N 3.49Å; S246-L248 PolarHBondContact O-N 3.17Å; S246-W249 WeakPolarHBondContact O-CB 3.29Å; S246-W249 PolarHBondContact O-N 3.14Å; S246-W249 VanDerWaalsContact O-N 3.13Å; S246-Y250 WeakPolarHBondContact O-CD2 3.39Å
247	T	93.4	Very high	90.6	Very high	87 Å²	87	64.2 Å²	64.2	53%	0.534	35%	0.349	S	S	.	.	H	α-helix	trans	-58.2	-33.7	173.6	-40.3	0	0	0	0	112.7	P245 W249 Y250 F251	P245-T247 PolarHBondContact O-N 2.9Å; P245-T247 VanDerWaalsContact O-N 3.07Å; T247-W249 PolarHBondContact O-N 2.73Å; T247-Y250 PolarHBondContact O-N 3.21Å; T247-F251 HydrophobicContact CG2-CD2 3.95Å; T247-F251 HydrophobicContact CG2-CE2 3.62Å; T247-F251 VanDerWaalsContact O-CD2 3.29Å; T247-F251 WeakPolarHBondContact O-CD2 3.5Å; T247-F251 PolarHBondContact O-N 3.43Å; T247-F251 VanDerWaalsContact O-N 3.17Å
248	L	93.6	Very high	91	Very high	55 Å²	55	71.7 Å²	71.7	29%	0.288	38%	0.382	S	S	.	.	H	α-helix	trans	-58.8	-37.8	177.4	178.5	63.5	0	0	0	111.4	L244 P245 S246 Y250 F251 L252	L244-L248 HydrophobicContact CD2-CD2 3.65Å; P245-L248 HydrophobicContact CG-CB 4.28Å; P245-L248 VanDerWaalsContact O-CB 3.25Å; P245-L248 WeakPolarHBondContact O-CB 3.15Å; P245-L248 PolarHBondContact O-N 3.21Å; S246-L248 PolarHBondContact O-N 3.17Å; L248-Y250 PolarHBondContact O-N 3.16Å; L248-F251 PolarHBondContact O-N 3Å; L248-L252 HydrophobicContact CD1-CD1 4.21Å; L248-L252 HydrophobicContact CD1-CG 4.23Å; L248-L252 HydrophobicContact CG-CD1 4.02Å; L248-L252 HydrophobicContact CG-CG 4.42Å; L248-L252 WeakPolarHBondContact O-CG 3.43Å; L248-L252 PolarHBondContact O-N 3.17Å
249	W	97	Very high	91.7	Very high	4 Å²	4	68.3 Å²	68.3	2%	0.015	37%	0.367	C	S	.	.	H	α-helix	trans	-60.2	-45.7	178.2	-176.9	86.3	0	0	0	111.5	S246 T247 F251 L252 M253 G293 G297 M300 L302 P306 F309	S246-W249 WeakPolarHBondContact O-CB 3.29Å; S246-W249 PolarHBondContact O-N 3.14Å; S246-W249 VanDerWaalsContact O-N 3.13Å; T247-W249 PolarHBondContact O-N 2.73Å; W249-F251 VanDerWaalsContact C-N 3.35Å; W249-F251 PolarHBondContact O-N 2.53Å; W249-L252 PolarHBondContact O-N 2.88Å; W249-M253 HydrophobicContact CD2-CG 3.78Å; W249-M253 VanDerWaalsContact CE2-CG 3.42Å; W249-M253 HydrophobicContact CE3-CG 4.27Å; W249-M253 HydrophobicContact CG-CG 4.25Å; W249-M253 HydrophobicContact CH2-CB 4.46Å; W249-M253 HydrophobicContact CH2-CG 4.14Å; W249-M253 HydrophobicContact CZ2-CB 4.43Å; W249-M253 HydrophobicContact CZ2-CG 3.65Å; W249-M253 HydrophobicContact CZ3-CB 4.5Å; W249-M253 HydrophobicContact CZ3-CG 4.42Å; W249-M253 WeakPolarHBondContact O-CB 3.44Å; W249-M253 WeakPolarHBondContact O-CG 3.02Å; W249-M253 PolarHBondContact O-N 3.34Å; W249-G293 PolarHBondContact NE1-O 3.36Å; W249-G297 VanDerWaalsContact NE1-CA 3.26Å; W249-M300 HydrophobicContact CB-SD 3.95Å; W249-L302 HydrophobicContact CB-CD1 3.92Å; W249-L302 HydrophobicContact CD2-CD1 3.58Å; W249-L302 HydrophobicContact CE3-CD1 3.59Å; W249-L302 HydrophobicContact CG-CD1 3.75Å; W249-L302 HydrophobicContact CZ3-CD1 4.33Å; W249-P306 HydrophobicContact CZ2-CG 4.44Å; W249-F309 AromaticContact CH2-CD2 3.53Å; W249-F309 HydrophobicContact CH2-CD2 3.53Å; W249-F309 AromaticContact CH2-CE2 3.46Å; W249-F309 HydrophobicContact CH2-CE2 3.46Å; W249-F309 VanDerWaalsContact CH2-CE2 3.46Å; W249-F309 AromaticContact CZ2-CD2 3.58Å; W249-F309 HydrophobicContact CZ2-CD2 3.58Å; W249-F309 AromaticContact CZ2-CE2 3.86Å; W249-F309 HydrophobicContact CZ2-CE2 3.86Å; W249-F309 HydrophobicContact CZ3-CE2 4.31Å
250	Y	96.3	Very high	92.4	Very high	127 Å²	127	64.4 Å²	64.4	50%	0.498	34%	0.34	S	S	.	.	H	α-helix	trans	-63.5	-39.7	177.4	-65.6	-78.2	0	0	0	112.2	S246 T247 L248 L252 M253 A254 L302	S246-Y250 WeakPolarHBondContact O-CD2 3.39Å; T247-Y250 PolarHBondContact O-N 3.21Å; L248-Y250 PolarHBondContact O-N 3.16Å; Y250-L252 VanDerWaalsContact C-N 3.32Å; Y250-L252 PolarHBondContact O-N 3.02Å; Y250-M253 PolarHBondContact O-N 3.15Å; Y250-A254 VanDerWaalsContact O-CB 3.26Å; Y250-A254 WeakPolarHBondContact O-CB 3.34Å; Y250-A254 PolarHBondContact O-N 3.22Å; Y250-L302 HydrophobicContact CE2-CD1 4.3Å; Y250-L302 HydrophobicContact CE2-CD2 4.39Å
251	F	96.1	Very high	93	Very high	150 Å²	150	67.3 Å²	67.3	66%	0.658	35%	0.354	S	S	*	.	H	α-helix	trans	-63.6	-35.2	175.5	-81.8	-67.6	0	0	0	113.2	T247 L248 W249 P255	T247-F251 HydrophobicContact CG2-CD2 3.95Å; T247-F251 HydrophobicContact CG2-CE2 3.62Å; T247-F251 VanDerWaalsContact O-CD2 3.29Å; T247-F251 WeakPolarHBondContact O-CD2 3.5Å; T247-F251 PolarHBondContact O-N 3.43Å; T247-F251 VanDerWaalsContact O-N 3.17Å; L248-F251 PolarHBondContact O-N 3Å; W249-F251 VanDerWaalsContact C-N 3.35Å; W249-F251 PolarHBondContact O-N 2.53Å; F251-P255 WeakPolarHBondContact O-CD 3.45Å
252	L	96.3	Very high	93.6	Very high	14 Å²	14	68.3 Å²	68.3	7%	0.073	36%	0.355	C	S	.	.	H	α-helix	trans	-79.4	-38.1	177.9	-66.5	175.8	0	0	0	112.3	I229 L230 L248 W249 Y250 L296	I229-L252 HydrophobicContact CB-CD2 4.15Å; I229-L252 HydrophobicContact CD1-CD2 4.41Å; I229-L252 HydrophobicContact CG2-CD1 3.94Å; I229-L252 HydrophobicContact CG2-CD2 3.6Å; I229-L252 HydrophobicContact CG2-CG 4.45Å; L230-L252 HydrophobicContact CD2-CB 4Å; L230-L252 HydrophobicContact CD2-CD1 3.83Å; L248-L252 HydrophobicContact CD1-CD1 4.21Å; L248-L252 HydrophobicContact CD1-CG 4.23Å; L248-L252 HydrophobicContact CG-CD1 4.02Å; L248-L252 HydrophobicContact CG-CG 4.42Å; L248-L252 WeakPolarHBondContact O-CG 3.43Å; L248-L252 PolarHBondContact O-N 3.17Å; W249-L252 PolarHBondContact O-N 2.88Å; Y250-L252 VanDerWaalsContact C-N 3.32Å; Y250-L252 PolarHBondContact O-N 3.02Å; L252-L296 HydrophobicContact CD1-CD2 4.43Å
253	M	97.8	Very high	94.3	Very high	2 Å²	2	64.3 Å²	64.3	1%	0.01	33%	0.327	C	S	.	.	H	α-helix	trans	-80.2	-29.1	-177.2	-68.8	-48.1	-62.4	0	0	113.6	L230 W249 Y250 I256 L257 G293 F309	L230-M253 HydrophobicContact CD1-SD 4.18Å; L230-M253 HydrophobicContact CD2-SD 4.37Å; W249-M253 HydrophobicContact CD2-CG 3.78Å; W249-M253 VanDerWaalsContact CE2-CG 3.42Å; W249-M253 HydrophobicContact CE3-CG 4.27Å; W249-M253 HydrophobicContact CG-CG 4.25Å; W249-M253 HydrophobicContact CH2-CB 4.46Å; W249-M253 HydrophobicContact CH2-CG 4.14Å; W249-M253 HydrophobicContact CZ2-CB 4.43Å; W249-M253 HydrophobicContact CZ2-CG 3.65Å; W249-M253 HydrophobicContact CZ3-CB 4.5Å; W249-M253 HydrophobicContact CZ3-CG 4.42Å; W249-M253 WeakPolarHBondContact O-CB 3.44Å; W249-M253 WeakPolarHBondContact O-CG 3.02Å; W249-M253 PolarHBondContact O-N 3.34Å; Y250-M253 PolarHBondContact O-N 3.15Å; M253-I256 HydrophobicContact CE-CB 4.27Å; M253-I256 HydrophobicContact CE-CD1 4.18Å; M253-I256 HydrophobicContact CE-CG2 4.04Å; M253-I256 WeakPolarHBondContact O-CB 3.32Å; M253-I256 PolarHBondContact O-N 2.82Å; M253-I256 HydrophobicContact SD-CD1 3.84Å; M253-L257 WeakPolarHBondContact O-CB 3.37Å; M253-L257 PolarHBondContact O-N 3.11Å; M253-G293 WeakPolarHBondContact SD-CA 3.33Å; M253-F309 HydrophobicContact CB-CE2 3.7Å; M253-F309 HydrophobicContact CB-CZ 3.74Å; M253-F309 HydrophobicContact CE-CB 4.29Å; M253-F309 HydrophobicContact CE-CD1 3.43Å; M253-F309 VanDerWaalsContact CE-CD1 3.43Å; M253-F309 HydrophobicContact CE-CD2 3.64Å; M253-F309 HydrophobicContact CE-CE1 3.44Å; M253-F309 VanDerWaalsContact CE-CE1 3.44Å; M253-F309 HydrophobicContact CE-CE2 3.67Å; M253-F309 HydrophobicContact CE-CG 3.52Å; M253-F309 HydrophobicContact CE-CZ 3.57Å; M253-F309 HydrophobicContact CG-CD2 4.44Å; M253-F309 HydrophobicContact CG-CE2 4.02Å; M253-F309 HydrophobicContact CG-CZ 4.37Å
254	A	97.2	Very high	94.8	Very high	41 Å²	41	56.6 Å²	56.6	34%	0.339	29%	0.291	S	S	.	.	H	α-helix	trans	-59.3	-47.9	179.3	0	0	0	0	0	112.8	Y250 I256 L257 F258	Y250-A254 VanDerWaalsContact O-CB 3.26Å; Y250-A254 WeakPolarHBondContact O-CB 3.34Å; Y250-A254 PolarHBondContact O-N 3.22Å; A254-I256 VanDerWaalsContact C-N 3.33Å; A254-I256 PolarHBondContact O-N 3.01Å; A254-L257 WeakPolarHBondContact O-CB 3.43Å; A254-L257 PolarHBondContact O-N 3.03Å; A254-F258 WeakPolarHBondContact O-CD2 3.41Å; A254-F258 PolarHBondContact O-N 3.37Å
255	P	97.1	Very high	94.9	Very high	50 Å²	50	55.7 Å²	55.7	33%	0.325	29%	0.292	S	S	.	.	H	α-helix	trans	-63	-35.6	173.8	-23.2	34.3	0	0	0	113.6	L226 F251 F258 L259	L226-P255 HydrophobicContact CD1-CB 3.69Å; L226-P255 HydrophobicContact CD2-CB 4.25Å; L226-P255 HydrophobicContact CD2-CG 4.46Å; F251-P255 WeakPolarHBondContact O-CD 3.45Å; P255-F258 PolarHBondContact O-N 2.93Å; P255-L259 WeakPolarHBondContact O-CG 3.36Å; P255-L259 PolarHBondContact O-N 3.03Å
256	I	97	Very high	94.8	Very high	0 Å²	0	54.1 Å²	54.1	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-60.7	-48.8	173.9	-67.6	179.6	0	0	0	109.6	F223 L226 L230 M253 A254 F258 L259 E260	F223-I256 HydrophobicContact CD1-CG2 4.36Å; F223-I256 HydrophobicContact CE1-CG2 4.33Å; L226-I256 HydrophobicContact CB-CD1 4.04Å; L226-I256 HydrophobicContact CB-CG1 3.91Å; L226-I256 HydrophobicContact CD1-CG1 3.72Å; L226-I256 HydrophobicContact CG-CG1 4.41Å; L230-I256 HydrophobicContact CD1-CD1 3.68Å; M253-I256 HydrophobicContact CE-CB 4.27Å; M253-I256 HydrophobicContact CE-CD1 4.18Å; M253-I256 HydrophobicContact CE-CG2 4.04Å; M253-I256 WeakPolarHBondContact O-CB 3.32Å; M253-I256 PolarHBondContact O-N 2.82Å; M253-I256 HydrophobicContact SD-CD1 3.84Å; A254-I256 VanDerWaalsContact C-N 3.33Å; A254-I256 PolarHBondContact O-N 3.01Å; I256-F258 PolarHBondContact O-N 3.31Å; I256-L259 WeakPolarHBondContact O-CB 3.24Å; I256-L259 PolarHBondContact O-N 3.23Å; I256-L259 VanDerWaalsContact O-N 3.16Å; I256-E260 HydrophobicContact CG2-CG 4.33Å; I256-E260 VanDerWaalsContact CG2-OE1 3.29Å; I256-E260 WeakPolarHBondContact CG2-OE1 3.5Å; I256-E260 WeakPolarHBondContact O-CG 3.47Å; I256-E260 PolarHBondContact O-N 3.31Å
257	L	97.7	Very high	94.6	Very high	56 Å²	56	52.6 Å²	52.6	29%	0.293	26%	0.264	S	S	.	.	H	α-helix	trans	-58.9	-44.2	177.8	-177.3	63.2	0	0	0	111.9	M253 A254 L259 E260 M261 F308 F309	M253-L257 WeakPolarHBondContact O-CB 3.37Å; M253-L257 PolarHBondContact O-N 3.11Å; A254-L257 WeakPolarHBondContact O-CB 3.43Å; A254-L257 PolarHBondContact O-N 3.03Å; L257-L259 VanDerWaalsContact C-N 3.34Å; L257-L259 PolarHBondContact O-N 3.38Å; L257-E260 PolarHBondContact O-N 3.17Å; L257-M261 HydrophobicContact CD1-CG 4.35Å; L257-M261 HydrophobicContact CG-CG 4.44Å; L257-M261 WeakPolarHBondContact O-CB 3.37Å; L257-M261 VanDerWaalsContact O-CG 3.27Å; L257-M261 WeakPolarHBondContact O-CG 3.39Å; L257-M261 PolarHBondContact O-N 3.31Å; L257-F308 HydrophobicContact CD1-CE1 4.07Å; L257-F308 HydrophobicContact CD1-CZ 4.3Å; L257-F309 HydrophobicContact CB-CE1 4.1Å; L257-F309 HydrophobicContact CB-CZ 4.08Å; L257-F309 HydrophobicContact CD1-CE1 4.12Å; L257-F309 HydrophobicContact CD1-CZ 4.47Å
258	F	96.9	Very high	94.2	Very high	157 Å²	157	54.9 Å²	54.9	69%	0.689	27%	0.27	S	S	*	.	H	α-helix	trans	-63.3	-40.3	176.7	-76.2	-64.7	0	0	0	112.7	A254 P255 I256 K262	A254-F258 WeakPolarHBondContact O-CD2 3.41Å; A254-F258 PolarHBondContact O-N 3.37Å; P255-F258 PolarHBondContact O-N 2.93Å; I256-F258 PolarHBondContact O-N 3.31Å; F258-K262 PolarHBondContact O-N 2.83Å
259	L	95.7	Very high	93.5	Very high	32 Å²	32	56.9 Å²	56.9	17%	0.168	29%	0.289	C	S	.	.	H	α-helix	trans	-65.1	-40.8	174.7	-72.3	172.1	0	0	0	111.1	F213 F223 L226 P255 I256 L257 K262 I263	F213-L259 HydrophobicContact CE2-CD2 4.13Å; F213-L259 HydrophobicContact CZ-CD2 4.49Å; F223-L259 HydrophobicContact CD1-CB 4.14Å; F223-L259 HydrophobicContact CD1-CD1 4.09Å; F223-L259 HydrophobicContact CE1-CB 3.37Å; F223-L259 HydrophobicContact CE1-CD1 4.16Å; F223-L259 HydrophobicContact CE1-CG 4.42Å; F223-L259 HydrophobicContact CE2-CB 4.3Å; F223-L259 HydrophobicContact CG-CD1 4.49Å; F223-L259 HydrophobicContact CZ-CB 3.48Å; F223-L259 VanDerWaalsContact CZ-CB 3.48Å; L226-L259 HydrophobicContact CD1-CD1 4.08Å; P255-L259 WeakPolarHBondContact O-CG 3.36Å; P255-L259 PolarHBondContact O-N 3.03Å; I256-L259 WeakPolarHBondContact O-CB 3.24Å; I256-L259 PolarHBondContact O-N 3.23Å; I256-L259 VanDerWaalsContact O-N 3.16Å; L257-L259 VanDerWaalsContact C-N 3.34Å; L257-L259 PolarHBondContact O-N 3.38Å; L259-K262 WeakPolarHBondContact O-CB 3.39Å; L259-K262 PolarHBondContact O-N 3.3Å; L259-I263 WeakPolarHBondContact O-CB 3.45Å; L259-I263 VanDerWaalsContact O-CG1 3.25Å; L259-I263 WeakPolarHBondContact O-CG1 3.43Å; L259-I263 PolarHBondContact O-N 3.44Å
260	E	95.4	Very high	92	Very high	3 Å²	3	57.6 Å²	57.6	1%	0.014	30%	0.297	C	S	.	.	H	α-helix	trans	-63.4	-51.3	175.8	-75.7	172.7	179.4	0	0	112	F223 I256 L257 K262 I263 Y264 N290	F223-E260 HydrophobicContact CE1-CG 3.87Å; F223-E260 HydrophobicContact CZ-CG 4.13Å; I256-E260 HydrophobicContact CG2-CG 4.33Å; I256-E260 VanDerWaalsContact CG2-OE1 3.29Å; I256-E260 WeakPolarHBondContact CG2-OE1 3.5Å; I256-E260 WeakPolarHBondContact O-CG 3.47Å; I256-E260 PolarHBondContact O-N 3.31Å; L257-E260 PolarHBondContact O-N 3.17Å; E260-K262 PolarHBondContact O-N 3.18Å; E260-K262 VanDerWaalsContact O-N 3.08Å; E260-I263 PolarHBondContact O-N 3.04Å; E260-Y264 HydrophobicContact CB-CD2 4.04Å; E260-Y264 HydrophobicContact CB-CE2 4.17Å; E260-Y264 HydrophobicContact CG-CD2 4.36Å; E260-Y264 HydrophobicContact CG-CE2 3.99Å; E260-Y264 WeakPolarHBondContact O-CA 3.4Å; E260-Y264 WeakPolarHBondContact O-CB 3.15Å; E260-Y264 PolarHBondContact O-N 2.98Å; E260-N290 PolarHBondContact OE1-ND2 3.34Å; E260-N290 PolarHBondContact OE1-OD1 2.97Å; E260-N290 PolarHBondContact OE2-OD1 3.36Å
261	M	94.5	Very high	91.1	Very high	130 Å²	130	53.8 Å²	53.8	64%	0.64	30%	0.297	S	S	*	.	H	α-helix	trans	-53.4	-36.9	177.3	-71.9	-55.9	-63.4	0	0	111.5	L257 G265	L257-M261 HydrophobicContact CD1-CG 4.35Å; L257-M261 HydrophobicContact CG-CG 4.44Å; L257-M261 WeakPolarHBondContact O-CB 3.37Å; L257-M261 VanDerWaalsContact O-CG 3.27Å; L257-M261 WeakPolarHBondContact O-CG 3.39Å; L257-M261 PolarHBondContact O-N 3.31Å; M261-G265 VanDerWaalsContact O-CA 3.24Å; M261-G265 WeakPolarHBondContact O-CA 3.44Å; M261-G265 PolarHBondContact O-N 3.48Å
262	K	92.6	Very high	90.1	Very high	93 Å²	93	50.4 Å²	50.4	40%	0.404	28%	0.283	S	S	.	.	H	α-helix	trans	-70.3	-51.7	174.1	-177.6	170.7	-175.5	166.5	0	112.9	F213 F258 L259 E260 Q266	F213-K262 HydrophobicContact CE1-CD 4.14Å; F213-K262 VanDerWaalsContact CE1-CE 3.41Å; F213-K262 HydrophobicContact CZ-CD 3.88Å; F258-K262 PolarHBondContact O-N 2.83Å; L259-K262 WeakPolarHBondContact O-CB 3.39Å; L259-K262 PolarHBondContact O-N 3.3Å; E260-K262 PolarHBondContact O-N 3.18Å; E260-K262 VanDerWaalsContact O-N 3.08Å; K262-Q266 WeakPolarHBondContact O-CB 3.47Å; K262-Q266 WeakPolarHBondContact O-CG 3.24Å; K262-Q266 PolarHBondContact O-N 3.17Å
263	I	91.7	Very high	89.3	Confident	4 Å²	4	51.9 Å²	51.9	2%	0.021	29%	0.288	C	S	.	.	H	α-helix	trans	-73.4	-50.1	-173.1	-64.3	-63.8	0	0	0	110.8	V219 F223 L259 E260 G265 Q266 W267	V219-I263 HydrophobicContact CG1-CD1 4.29Å; V219-I263 HydrophobicContact CG2-CD1 3.62Å; F223-I263 HydrophobicContact CE2-CG1 4.13Å; F223-I263 HydrophobicContact CZ-CG1 4.29Å; L259-I263 WeakPolarHBondContact O-CB 3.45Å; L259-I263 VanDerWaalsContact O-CG1 3.25Å; L259-I263 WeakPolarHBondContact O-CG1 3.43Å; L259-I263 PolarHBondContact O-N 3.44Å; E260-I263 PolarHBondContact O-N 3.04Å; I263-G265 VanDerWaalsContact C-N 3.34Å; I263-Q266 WeakPolarHBondContact O-CB 3.32Å; I263-Q266 PolarHBondContact O-N 3.42Å; I263-W267 HydrophobicContact CG2-CD2 4.25Å; I263-W267 VanDerWaalsContact CG2-CE2 3.45Å; I263-W267 HydrophobicContact CG2-CH2 4.35Å; I263-W267 HydrophobicContact CG2-CZ2 3.49Å; I263-W267 VanDerWaalsContact CG2-CZ2 3.49Å; I263-W267 VanDerWaalsContact O-CG 3.22Å; I263-W267 PolarHBondContact O-N 2.94Å
264	Y	92.3	Very high	88.6	Confident	8 Å²	8	58 Å²	58	3%	0.031	31%	0.311	C	S	.	.	H	α-helix	trans	-66.9	-36.4	176.4	-64.2	-4.8	0	0	0	111.5	E260 Q266 W267 M268 S286 N290 I312 Y316	E260-Y264 HydrophobicContact CB-CD2 4.04Å; E260-Y264 HydrophobicContact CB-CE2 4.17Å; E260-Y264 HydrophobicContact CG-CD2 4.36Å; E260-Y264 HydrophobicContact CG-CE2 3.99Å; E260-Y264 WeakPolarHBondContact O-CA 3.4Å; E260-Y264 WeakPolarHBondContact O-CB 3.15Å; E260-Y264 PolarHBondContact O-N 2.98Å; Y264-Q266 VanDerWaalsContact C-N 3.34Å; Y264-Q266 PolarHBondContact O-N 2.9Å; Y264-W267 HydrophobicContact CD1-CD2 4.03Å; Y264-W267 AromaticContact CD1-CE3 3.47Å; Y264-W267 HydrophobicContact CD1-CE3 3.47Å; Y264-W267 VanDerWaalsContact CD1-CE3 3.47Å; Y264-W267 AromaticContact CD1-CH2 3.86Å; Y264-W267 HydrophobicContact CD1-CH2 3.86Å; Y264-W267 HydrophobicContact CD1-CZ2 4.35Å; Y264-W267 AromaticContact CD1-CZ3 3.4Å; Y264-W267 HydrophobicContact CD1-CZ3 3.4Å; Y264-W267 AromaticContact CE1-CE3 3.88Å; Y264-W267 HydrophobicContact CE1-CE3 3.88Å; Y264-W267 AromaticContact CE1-CH2 3.5Å; Y264-W267 HydrophobicContact CE1-CH2 3.5Å; Y264-W267 VanDerWaalsContact CE1-CH2 3.5Å; Y264-W267 HydrophobicContact CE1-CZ2 4.28Å; Y264-W267 AromaticContact CE1-CZ3 3.27Å; Y264-W267 HydrophobicContact CE1-CZ3 3.27Å; Y264-W267 HydrophobicContact CG-CE3 4.39Å; Y264-W267 WeakPolarHBondContact O-CB 3.14Å; Y264-W267 PolarHBondContact O-N 3.07Å; Y264-M268 WeakPolarHBondContact O-CG 3.3Å; Y264-M268 PolarHBondContact O-N 3.37Å; Y264-S286 PolarHBondContact OH-OG 3.26Å; Y264-S286 VanDerWaalsContact OH-OG 3.14Å; Y264-N290 PolarHBondContact OH-ND2 2.8Å; Y264-I312 HydrophobicContact CD2-CG2 4.25Å; Y264-I312 HydrophobicContact CE2-CG2 3.77Å; Y264-Y316 AromaticContact CD1-CD1 3.94Å; Y264-Y316 HydrophobicContact CD1-CD1 3.94Å; Y264-Y316 HydrophobicContact CD1-CE1 4.06Å; Y264-Y316 HydrophobicContact CD1-CG 4.32Å; Y264-Y316 AromaticContact CD2-CD1 3.94Å; Y264-Y316 HydrophobicContact CD2-CD1 3.94Å; Y264-Y316 AromaticContact CD2-CD2 3.39Å; Y264-Y316 HydrophobicContact CD2-CD2 3.39Å; Y264-Y316 AromaticContact CD2-CE1 3.87Å; Y264-Y316 HydrophobicContact CD2-CE1 3.87Å; Y264-Y316 AromaticContact CD2-CE2 3.29Å; Y264-Y316 HydrophobicContact CD2-CE2 3.29Å; Y264-Y316 AromaticContact CD2-CG 3.71Å; Y264-Y316 HydrophobicContact CD2-CG 3.71Å; Y264-Y316 AromaticContact CD2-CZ 3.55Å; Y264-Y316 HydrophobicContact CE1-CD1 4.15Å; Y264-Y316 HydrophobicContact CE1-CG 4.19Å; Y264-Y316 HydrophobicContact CE2-CD1 4.12Å; Y264-Y316 AromaticContact CE2-CD2 3.36Å; Y264-Y316 HydrophobicContact CE2-CD2 3.36Å; Y264-Y316 HydrophobicContact CE2-CE1 4.5Å; Y264-Y316 AromaticContact CE2-CE2 3.8Å; Y264-Y316 HydrophobicContact CE2-CE2 3.8Å; Y264-Y316 AromaticContact CE2-CG 3.53Å; Y264-Y316 HydrophobicContact CE2-CG 3.53Å; Y264-Y316 AromaticContact CG-CD1 3.84Å; Y264-Y316 HydrophobicContact CG-CD1 3.84Å; Y264-Y316 HydrophobicContact CG-CD2 4.14Å; Y264-Y316 AromaticContact CG-CE1 3.6Å; Y264-Y316 HydrophobicContact CG-CE1 3.6Å; Y264-Y316 AromaticContact CG-CE2 3.91Å; Y264-Y316 HydrophobicContact CG-CE2 3.91Å; Y264-Y316 HydrophobicContact CG-CG 4.1Å; Y264-Y316 AromaticContact CG-CZ 3.64Å; Y264-Y316 AromaticContact CZ-CG 3.79Å
265	G	89.6	Confident	88	Confident	24 Å²	24	56.7 Å²	56.7	25%	0.247	30%	0.298	C	S	.	.	H	α-helix	trans	-60.1	-41.8	169.9	0	0	0	0	0	112.6	M261 I263 M268 S269	M261-G265 VanDerWaalsContact O-CA 3.24Å; M261-G265 WeakPolarHBondContact O-CA 3.44Å; M261-G265 PolarHBondContact O-N 3.48Å; I263-G265 VanDerWaalsContact C-N 3.34Å; G265-M268 PolarHBondContact O-N 2.83Å; G265-S269 VanDerWaalsContact O-CB 3.28Å; G265-S269 WeakPolarHBondContact O-CB 3.41Å; G265-S269 PolarHBondContact O-N 2.86Å; G265-S269 PolarHBondContact O-OG 3.22Å
266	Q	89.8	Confident	87.1	Confident	51 Å²	51	57.3 Å²	57.3	24%	0.238	30%	0.303	C	S	.	.	H	α-helix	trans	-67.5	-34.4	174.3	-78	176.2	-8.2	0	0	113	K262 I263 Y264 M268 R273	K262-Q266 WeakPolarHBondContact O-CB 3.47Å; K262-Q266 WeakPolarHBondContact O-CG 3.24Å; K262-Q266 PolarHBondContact O-N 3.17Å; I263-Q266 WeakPolarHBondContact O-CB 3.32Å; I263-Q266 PolarHBondContact O-N 3.42Å; Y264-Q266 VanDerWaalsContact C-N 3.34Å; Y264-Q266 PolarHBondContact O-N 2.9Å; Q266-M268 VanDerWaalsContact C-N 3.33Å; Q266-R273 HydrophobicContact CB-CB 4.07Å
267	W	89.1	Confident	86.2	Confident	17 Å²	17	61.3 Å²	61.3	6%	0.064	32%	0.321	C	S	.	.	H	α-helix	trans	-63.3	-40.4	175.3	-69.9	0.3	0	0	0	111.9	I263 Y264 L275 N283 Y316	I263-W267 HydrophobicContact CG2-CD2 4.25Å; I263-W267 VanDerWaalsContact CG2-CE2 3.45Å; I263-W267 HydrophobicContact CG2-CH2 4.35Å; I263-W267 HydrophobicContact CG2-CZ2 3.49Å; I263-W267 VanDerWaalsContact CG2-CZ2 3.49Å; I263-W267 VanDerWaalsContact O-CG 3.22Å; I263-W267 PolarHBondContact O-N 2.94Å; Y264-W267 HydrophobicContact CD1-CD2 4.03Å; Y264-W267 AromaticContact CD1-CE3 3.47Å; Y264-W267 HydrophobicContact CD1-CE3 3.47Å; Y264-W267 VanDerWaalsContact CD1-CE3 3.47Å; Y264-W267 AromaticContact CD1-CH2 3.86Å; Y264-W267 HydrophobicContact CD1-CH2 3.86Å; Y264-W267 HydrophobicContact CD1-CZ2 4.35Å; Y264-W267 AromaticContact CD1-CZ3 3.4Å; Y264-W267 HydrophobicContact CD1-CZ3 3.4Å; Y264-W267 AromaticContact CE1-CE3 3.88Å; Y264-W267 HydrophobicContact CE1-CE3 3.88Å; Y264-W267 AromaticContact CE1-CH2 3.5Å; Y264-W267 HydrophobicContact CE1-CH2 3.5Å; Y264-W267 VanDerWaalsContact CE1-CH2 3.5Å; Y264-W267 HydrophobicContact CE1-CZ2 4.28Å; Y264-W267 AromaticContact CE1-CZ3 3.27Å; Y264-W267 HydrophobicContact CE1-CZ3 3.27Å; Y264-W267 HydrophobicContact CG-CE3 4.39Å; Y264-W267 WeakPolarHBondContact O-CB 3.14Å; Y264-W267 PolarHBondContact O-N 3.07Å; W267-L275 HydrophobicContact CB-CB 3.86Å; W267-L275 HydrophobicContact CD2-CB 4.33Å; W267-L275 HydrophobicContact CD2-CD1 3.7Å; W267-L275 HydrophobicContact CD2-CD2 4.43Å; W267-L275 HydrophobicContact CD2-CG 4.36Å; W267-L275 HydrophobicContact CE3-CD1 3.96Å; W267-L275 HydrophobicContact CE3-CD2 4.11Å; W267-L275 HydrophobicContact CG-CB 3.9Å; W267-L275 HydrophobicContact CG-CD1 4.09Å; W267-L275 HydrophobicContact CG-CG 4.45Å; W267-L275 HydrophobicContact CH2-CD1 4.43Å; W267-L275 HydrophobicContact CZ2-CD1 4.21Å; W267-L275 HydrophobicContact CZ3-CD1 4.3Å; W267-N283 HydrophobicContact CH2-CB 3.93Å; W267-N283 HydrophobicContact CZ2-CB 3.92Å; W267-N283 WeakPolarHBondContact CZ2-ND2 3.39Å; W267-Y316 AromaticContact CE3-CD1 3.82Å; W267-Y316 HydrophobicContact CE3-CD1 3.82Å; W267-Y316 HydrophobicContact CE3-CE1 4.11Å; W267-Y316 AromaticContact CZ3-CD1 3.9Å; W267-Y316 HydrophobicContact CZ3-CD1 3.9Å
268	M	84.1	Confident	85.5	Confident	134 Å²	134	59 Å²	59	66%	0.66	31%	0.309	S	S	*	.	H	α-helix	trans	-79.9	-46.9	180	-67	-172.8	-65.8	0	0	113.8	Y264 G265 Q266 G270 Y316	Y264-M268 WeakPolarHBondContact O-CG 3.3Å; Y264-M268 PolarHBondContact O-N 3.37Å; G265-M268 PolarHBondContact O-N 2.83Å; Q266-M268 VanDerWaalsContact C-N 3.33Å; M268-G270 PolarHBondContact O-N 3.01Å; M268-Y316 PolarHBondContact SD-OH 3.46Å
269	S	78.6	Confident	84.9	Confident	98 Å²	98	51.9 Å²	51.9	69%	0.685	28%	0.279	S	S	*	.	H	α-helix	trans	-68	-6	-170.3	52.8	0	0	0	0	115.2	G265	G265-S269 VanDerWaalsContact O-CB 3.28Å; G265-S269 WeakPolarHBondContact O-CB 3.41Å; G265-S269 PolarHBondContact O-N 2.86Å; G265-S269 PolarHBondContact O-OG 3.22Å
270	G	66	Low	84.3	Confident	18 Å²	18	51.3 Å²	51.3	19%	0.186	28%	0.276	C	S	.	.			trans	77.1	-175.5	177.9	0	0	0	0	0	113.9	M268	M268-G270 PolarHBondContact O-N 3.01Å
271	G	76.7	Confident	83.7	Confident	48 Å²	48	51.7 Å²	51.7	50%	0.495	28%	0.279	S	S	.	.	S	Bend	trans	92	-149.2	-175.8	0	0	0	0	0	113.9	R273 R274	G271-R273 VanDerWaalsContact C-N 3.26Å; G271-R273 PolarHBondContact O-N 2.93Å; G271-R274 PolarHBondContact O-N 3.16Å
272	Q	75	Confident	83.3	Confident	78 Å²	78	45.7 Å²	45.7	36%	0.364	25%	0.25	S	C	.	.	T	Hydrogen-bonded Turn	trans	-76.7	-9.8	-173.4	-58.9	-60.8	18.7	0	0	115	D109	D109-Q272 PolarHBondContact OD1-OE1 3.5Å; D109-Q272 VanDerWaalsContact OD1-OE1 3.14Å; D109-Q272 PolarHBondContact OD2-NE2 3.42Å; D109-Q272 PolarHBondContact OD2-OE1 3.2Å
273	R	80.5	Confident	83.2	Confident	46 Å²	46	41.3 Å²	41.3	17%	0.174	23%	0.231	C	C	.	.	T	Hydrogen-bonded Turn	trans	-117.3	16.9	177	-69.2	-170.3	165.3	-149.9	-7.6	113.5	A108 F213 R214 Q266 G271 L275	A108-R273 HydrophobicContact CB-CG 4.43Å; F213-R273 PolarHBondContact O-NH2 3.3Å; F213-R273 VanDerWaalsContact O-NH2 3.12Å; R214-R273 PolarHBondContact O-NH2 3.11Å; Q266-R273 HydrophobicContact CB-CB 4.07Å; G271-R273 VanDerWaalsContact C-N 3.26Å; G271-R273 PolarHBondContact O-N 2.93Å; R273-L275 PolarHBondContact O-N 3.09Å
274	R	83.7	Confident	83.2	Confident	131 Å²	131	41.2 Å²	41.2	49%	0.494	23%	0.23	S	C	.	.			trans	-54.7	138.9	170.7	-175.5	-179.8	-82.1	-173.9	-1.7	109.2	G271 S276 K277 V278	G271-R274 PolarHBondContact O-N 3.16Å; R274-S276 WeakPolarHBondContact CD-OG 3.37Å; R274-S276 WeakPolarHBondContact CG-OG 3.49Å; R274-S276 PolarHBondContact O-N 2.73Å; R274-S276 VanDerWaalsContact O-N 3.16Å; R274-K277 WeakPolarHBondContact O-CB 3.24Å; R274-K277 PolarHBondContact O-N 3.35Å; R274-V278 PolarHBondContact O-N 3.18Å
275	L	83.4	Confident	83.2	Confident	13 Å²	13	41.4 Å²	41.4	7%	0.068	23%	0.232	C	C	.	.	H	α-helix	trans	-53.2	-41.3	-178	-177.3	59.4	0	0	0	112.3	W267 R273 K277 V278 A279 V319 L320 T323	W267-L275 HydrophobicContact CB-CB 3.86Å; W267-L275 HydrophobicContact CD2-CB 4.33Å; W267-L275 HydrophobicContact CD2-CD1 3.7Å; W267-L275 HydrophobicContact CD2-CD2 4.43Å; W267-L275 HydrophobicContact CD2-CG 4.36Å; W267-L275 HydrophobicContact CE3-CD1 3.96Å; W267-L275 HydrophobicContact CE3-CD2 4.11Å; W267-L275 HydrophobicContact CG-CB 3.9Å; W267-L275 HydrophobicContact CG-CD1 4.09Å; W267-L275 HydrophobicContact CG-CG 4.45Å; W267-L275 HydrophobicContact CH2-CD1 4.43Å; W267-L275 HydrophobicContact CZ2-CD1 4.21Å; W267-L275 HydrophobicContact CZ3-CD1 4.3Å; R273-L275 PolarHBondContact O-N 3.09Å; L275-K277 PolarHBondContact O-N 2.91Å; L275-V278 PolarHBondContact O-N 2.71Å; L275-V278 VanDerWaalsContact O-N 3.16Å; L275-A279 HydrophobicContact CD1-CB 3.9Å; L275-A279 HydrophobicContact CG-CB 4.29Å; L275-A279 WeakPolarHBondContact O-CA 3.42Å; L275-A279 WeakPolarHBondContact O-CB 3.29Å; L275-A279 PolarHBondContact O-N 3.12Å; L275-V319 HydrophobicContact CD2-CG1 3.63Å; L275-L320 HydrophobicContact CD1-CD1 3.87Å; L275-T323 HydrophobicContact CG-CG2 4.22Å
276	S	79.7	Confident	83.4	Confident	62 Å²	62	40.2 Å²	40.2	43%	0.434	22%	0.22	S	C	.	.	H	α-helix	trans	-59	-17.2	177.4	66.6	0	0	0	0	115	R274 R327	R274-S276 WeakPolarHBondContact CD-OG 3.37Å; R274-S276 WeakPolarHBondContact CG-OG 3.49Å; R274-S276 PolarHBondContact O-N 2.73Å; R274-S276 VanDerWaalsContact O-N 3.16Å; S276-R327 PolarHBondContact O-NE 2.79Å; S276-R327 PolarHBondContact O-NH2 2.79Å
277	K	77.4	Confident	83.7	Confident	85 Å²	85	37.8 Å²	37.8	37%	0.37	21%	0.208	S	C	.	.	H	α-helix	trans	-98.8	-34.1	175.7	-71.5	-175.1	172.5	-177.4	0	113.6	R274 L275 R327	R274-K277 WeakPolarHBondContact O-CB 3.24Å; R274-K277 PolarHBondContact O-N 3.35Å; L275-K277 PolarHBondContact O-N 2.91Å; K277-R327 VanDerWaalsContact C-NH1 3.35Å; K277-R327 PolarHBondContact O-NH1 3.46Å; K277-R327 PolarHBondContact O-NH2 3.02Å
278	V	82.2	Confident	83.9	Confident	7 Å²	7	37.1 Å²	37.1	4%	0.042	21%	0.206	C	C	.	.	H	α-helix	trans	-110	-3.9	-171.2	-58.3	0	0	0	0	114.1	F112 P216 R274 L275 N280 N283	F112-V278 HydrophobicContact CE2-CG1 4.28Å; F112-V278 HydrophobicContact CZ-CG1 4.49Å; P216-V278 HydrophobicContact CB-CB 4.46Å; P216-V278 HydrophobicContact CB-CG1 4.18Å; R274-V278 PolarHBondContact O-N 3.18Å; L275-V278 PolarHBondContact O-N 2.71Å; L275-V278 VanDerWaalsContact O-N 3.16Å; V278-N280 PolarHBondContact O-N 2.84Å; V278-N280 PolarHBondContact O-ND2 3.16Å; V278-N283 PolarHBondContact O-OD1 2.88Å
279	A	84.8	Confident	84.5	Confident	8 Å²	8	30.8 Å²	30.8	7%	0.066	18%	0.175	C	C	.	.			trans	-53.7	122.4	179	0	0	0	0	0	110.6	L275 N283 L320 T323 L324 R327	L275-A279 HydrophobicContact CD1-CB 3.9Å; L275-A279 HydrophobicContact CG-CB 4.29Å; L275-A279 WeakPolarHBondContact O-CA 3.42Å; L275-A279 WeakPolarHBondContact O-CB 3.29Å; L275-A279 PolarHBondContact O-N 3.12Å; A279-N283 WeakPolarHBondContact CA-OD1 3.26Å; A279-L320 HydrophobicContact CB-CD1 4.48Å; A279-T323 HydrophobicContact CB-CG2 3.83Å; A279-L324 HydrophobicContact CB-CD2 3.91Å; A279-R327 PolarHBondContact O-NH1 3.27Å
280	N	83	Confident	85.5	Confident	20 Å²	20	26.1 Å²	26.1	11%	0.107	14%	0.142	C	C	.	.			trans	-150.2	160	175.4	69	80.3	0	0	0	109.4	V278 T282 N283	V278-N280 PolarHBondContact O-N 2.84Å; V278-N280 PolarHBondContact O-ND2 3.16Å; N280-T282 PolarHBondContact O-N 3.13Å; N280-T282 VanDerWaalsContact O-N 3.12Å; N280-T282 WeakPolarHBondContact OD1-CB 3.2Å; N280-T282 PolarHBondContact OD1-N 3.42Å; N280-T282 PolarHBondContact OD1-OG1 3.34Å; N280-N283 PolarHBondContact N-OD1 2.84Å; N280-N283 PolarHBondContact ND2-OD1 3.26Å; N280-N283 VanDerWaalsContact O-CB 3.3Å; N280-N283 WeakPolarHBondContact O-CB 3.47Å; N280-N283 PolarHBondContact O-N 3.49Å; N280-N283 PolarHBondContact O-OD1 3.18Å
281	P	83.2	Confident	87	Confident	10 Å²	10	25.3 Å²	25.3	7%	0.065	13%	0.134	C	C	.	.	G	3₁₀ helix	trans	-65.9	-20.8	-171.8	-20.5	32.7	0	0	0	114.1	N283 H284 V341 F342 F345	P281-N283 PolarHBondContact O-N 2.86Å; P281-H284 WeakPolarHBondContact O-CB 3.39Å; P281-H284 PolarHBondContact O-N 3.39Å; P281-H284 VanDerWaalsContact O-N 3.11Å; P281-H284 PolarHBondContact O-ND1 3.42Å; P281-V341 HydrophobicContact CB-CB 4Å; P281-V341 HydrophobicContact CB-CG1 3.61Å; P281-V341 VanDerWaalsContact CB-O 3.27Å; P281-V341 WeakPolarHBondContact CB-O 3.42Å; P281-V341 HydrophobicContact CG-CB 4.31Å; P281-V341 HydrophobicContact CG-CG1 4.27Å; P281-F342 HydrophobicContact CG-CE1 4.45Å; P281-F345 HydrophobicContact CB-CD2 4.27Å; P281-F345 HydrophobicContact CB-CE2 3.77Å; P281-F345 HydrophobicContact CG-CE2 3.92Å
282	T	86.7	Confident	88	Confident	5 Å²	5	23 Å²	23	3%	0.031	11%	0.11	C	C	.	.	G	3₁₀ helix	trans	-66	-17.9	174.1	76.6	0	0	0	0	113.3	I217 N220 F221 N280 H284 L285 V341 L344	I217-T282 HydrophobicContact CG2-CG2 3.96Å; N220-T282 PolarHBondContact ND2-OG1 2.81Å; F221-T282 HydrophobicContact CE2-CG2 3.92Å; F221-T282 HydrophobicContact CZ-CG2 4.4Å; N280-T282 PolarHBondContact O-N 3.13Å; N280-T282 VanDerWaalsContact O-N 3.12Å; N280-T282 WeakPolarHBondContact OD1-CB 3.2Å; N280-T282 PolarHBondContact OD1-N 3.42Å; N280-T282 PolarHBondContact OD1-OG1 3.34Å; T282-H284 PolarHBondContact O-N 2.88Å; T282-H284 VanDerWaalsContact O-N 3.17Å; T282-L285 VanDerWaalsContact O-CB 3.24Å; T282-L285 WeakPolarHBondContact O-CB 3.34Å; T282-L285 PolarHBondContact O-N 3.1Å; T282-V341 HydrophobicContact CG2-CG1 3.51Å; T282-L344 HydrophobicContact CG2-CD1 4.42Å
283	N	90	Very high	89.1	Confident	1 Å²	1	19.3 Å²	19.3	1%	0.005	9%	0.093	C	C	.	.	G	3₁₀ helix	trans	-59.9	-23.9	172.2	-64.4	126.2	0	0	0	112.3	N220 W267 V278 A279 N280 P281 L285 S286 L320	N220-N283 VanDerWaalsContact CG-ND2 3.29Å; N220-N283 PolarHBondContact ND2-ND2 3.49Å; N220-N283 PolarHBondContact OD1-ND2 2.79Å; W267-N283 HydrophobicContact CH2-CB 3.93Å; W267-N283 HydrophobicContact CZ2-CB 3.92Å; W267-N283 WeakPolarHBondContact CZ2-ND2 3.39Å; V278-N283 PolarHBondContact O-OD1 2.88Å; A279-N283 WeakPolarHBondContact CA-OD1 3.26Å; N280-N283 PolarHBondContact N-OD1 2.84Å; N280-N283 PolarHBondContact ND2-OD1 3.26Å; N280-N283 VanDerWaalsContact O-CB 3.3Å; N280-N283 WeakPolarHBondContact O-CB 3.47Å; N280-N283 PolarHBondContact O-N 3.49Å; N280-N283 PolarHBondContact O-OD1 3.18Å; P281-N283 PolarHBondContact O-N 2.86Å; N283-L285 PolarHBondContact O-N 3.45Å; N283-L285 VanDerWaalsContact O-N 3.15Å; N283-S286 PolarHBondContact O-N 3.37Å; N283-S286 VanDerWaalsContact O-N 3.16Å; N283-S286 PolarHBondContact O-OG 3.31Å; N283-L320 HydrophobicContact CB-CD1 3.79Å; N283-L320 HydrophobicContact CB-CD2 3.61Å; N283-L320 HydrophobicContact CB-CG 4.39Å
284	H	92	Very high	89.9	Confident	1 Å²	1	17.1 Å²	17.1	1%	0.005	9%	0.085	C	C	.	.	H	α-helix	trans	-59.2	-21.9	172.7	-75.2	92.6	0	0	0	113.3	P281 T282 S286 I287 V288 L324 L344 F345	P281-H284 WeakPolarHBondContact O-CB 3.39Å; P281-H284 PolarHBondContact O-N 3.39Å; P281-H284 VanDerWaalsContact O-N 3.11Å; P281-H284 PolarHBondContact O-ND1 3.42Å; T282-H284 PolarHBondContact O-N 2.88Å; T282-H284 VanDerWaalsContact O-N 3.17Å; H284-S286 VanDerWaalsContact C-N 3.27Å; H284-S286 PolarHBondContact O-N 3.42Å; H284-I287 PolarHBondContact O-N 3.43Å; H284-V288 WeakPolarHBondContact O-CB 3.4Å; H284-V288 WeakPolarHBondContact O-CG2 3.46Å; H284-V288 PolarHBondContact O-N 2.88Å; H284-L324 VanDerWaalsContact CE1-CD1 3.47Å; H284-L324 WeakPolarHBondContact CE1-CD1 3.25Å; H284-L344 HydrophobicContact CB-CB 4.01Å; H284-F345 AromaticContact CE1-CD1 3.42Å; H284-F345 VanDerWaalsContact CE1-CD1 3.42Å; H284-F345 WeakPolarHBondContact CE1-CD1 3.32Å; H284-F345 AromaticContact CE1-CD2 3.86Å; H284-F345 AromaticContact CE1-CE1 3.55Å; H284-F345 AromaticContact CE1-CE2 3.98Å; H284-F345 AromaticContact CE1-CG 3.62Å; H284-F345 AromaticContact CE1-CZ 3.86Å; H284-F345 AromaticContact NE2-CD1 3.59Å; H284-F345 AromaticContact NE2-CG 3.93Å
285	L	91.8	Very high	90.6	Very high	12 Å²	12	11.6 Å²	11.6	6%	0.063	7%	0.065	C	C	.	.	H	α-helix	trans	-61.5	-37	177	-173.7	58.7	0	0	0	112	L152 N220 F221 F223 A224 I227 T282 N283 G289	L152-L285 HydrophobicContact CD1-CD1 3.63Å; N220-L285 VanDerWaalsContact O-CD2 3.28Å; N220-L285 WeakPolarHBondContact O-CD2 3.42Å; F221-L285 HydrophobicContact CD1-CD2 4.09Å; F221-L285 HydrophobicContact CG-CD2 4.24Å; F223-L285 HydrophobicContact CB-CG 4.42Å; A224-L285 HydrophobicContact CB-CD2 4.02Å; I227-L285 HydrophobicContact CD1-CD1 3.64Å; I227-L285 HydrophobicContact CD1-CG 3.95Å; I227-L285 WeakPolarHBondContact CD1-O 3.33Å; T282-L285 VanDerWaalsContact O-CB 3.24Å; T282-L285 WeakPolarHBondContact O-CB 3.34Å; T282-L285 PolarHBondContact O-N 3.1Å; N283-L285 PolarHBondContact O-N 3.45Å; N283-L285 VanDerWaalsContact O-N 3.15Å; L285-G289 PolarHBondContact O-N 2.89Å
286	S	93.6	Very high	91.3	Very high	0 Å²	0	11 Å²	11	0%	0	6%	0.062	C	C	.	.	H	α-helix	trans	-64	-43.7	173.8	67.2	0	0	0	0	112.1	Y264 N283 H284 G289 N290	Y264-S286 PolarHBondContact OH-OG 3.26Å; Y264-S286 VanDerWaalsContact OH-OG 3.14Å; N283-S286 PolarHBondContact O-N 3.37Å; N283-S286 VanDerWaalsContact O-N 3.16Å; N283-S286 PolarHBondContact O-OG 3.31Å; H284-S286 VanDerWaalsContact C-N 3.27Å; H284-S286 PolarHBondContact O-N 3.42Å; S286-G289 PolarHBondContact O-N 2.94Å; S286-G289 VanDerWaalsContact O-N 3.14Å; S286-N290 PolarHBondContact O-N 2.92Å
287	I	95.5	Very high	92.1	Very high	0 Å²	0	8 Å²	8	0%	0	4%	0.041	C	C	.	.	H	α-helix	trans	-65.9	-42.1	178.8	-69.3	154.5	0	0	0	111.2	H284 G289 N290 F291 Y317 L320 A348	H284-I287 PolarHBondContact O-N 3.43Å; I287-G289 PolarHBondContact O-N 3.03Å; I287-N290 VanDerWaalsContact O-CB 3.31Å; I287-N290 WeakPolarHBondContact O-CB 3.45Å; I287-N290 PolarHBondContact O-N 3.09Å; I287-F291 HydrophobicContact CG2-CD2 3.93Å; I287-F291 HydrophobicContact CG2-CE2 3.39Å; I287-F291 HydrophobicContact CG2-CZ 4.1Å; I287-F291 WeakPolarHBondContact O-CD2 3.33Å; I287-F291 PolarHBondContact O-N 3.19Å; I287-Y317 HydrophobicContact CG2-CD2 4.28Å; I287-L320 HydrophobicContact CD1-CB 3.88Å; I287-L320 HydrophobicContact CD1-CD2 3.35Å; I287-L320 HydrophobicContact CD1-CG 4.24Å; I287-A348 HydrophobicContact CG2-CB 3.95Å
288	V	95	Very high	93	Very high	3 Å²	3	4.7 Å²	4.7	2%	0.018	3%	0.029	C	C	.	.	H	α-helix	trans	-60.6	-38.4	173.6	165	0	0	0	0	110.5	F231 H284 N290 F291 A292 A347 A348 F402	F231-V288 HydrophobicContact CZ-CG1 4.25Å; H284-V288 WeakPolarHBondContact O-CB 3.4Å; H284-V288 WeakPolarHBondContact O-CG2 3.46Å; H284-V288 PolarHBondContact O-N 2.88Å; V288-N290 VanDerWaalsContact C-N 3.31Å; V288-N290 PolarHBondContact O-N 3.42Å; V288-F291 PolarHBondContact O-N 3.13Å; V288-A292 WeakPolarHBondContact O-CB 3.43Å; V288-A292 PolarHBondContact O-N 3.04Å; V288-A347 HydrophobicContact CG2-CB 4.07Å; V288-A348 HydrophobicContact CG2-CB 4.2Å; V288-F402 HydrophobicContact CB-CE1 4.33Å; V288-F402 HydrophobicContact CG1-CE1 3.52Å; V288-F402 HydrophobicContact CG1-CZ 3.45Å; V288-F402 VanDerWaalsContact CG1-CZ 3.45Å; V288-F402 HydrophobicContact CG2-CE1 3.97Å; V288-F402 HydrophobicContact CG2-CZ 4.37Å
289	G	96.2	Very high	93.5	Very high	0 Å²	0	7.2 Å²	7.2	0%	0	5%	0.047	C	C	.	.	H	α-helix	trans	-58	-42.2	175.3	0	0	0	0	0	113	L285 S286 I287 A292 G293	L285-G289 PolarHBondContact O-N 2.89Å; S286-G289 PolarHBondContact O-N 2.94Å; S286-G289 VanDerWaalsContact O-N 3.14Å; I287-G289 PolarHBondContact O-N 3.03Å; G289-A292 PolarHBondContact O-N 3.32Å; G289-G293 PolarHBondContact O-N 3.09Å
290	N	98	Very high	93.9	Very high	0 Å²	0	8.3 Å²	8.3	0%	0	5%	0.051	C	C	.	.	H	α-helix	trans	-57.6	-52.7	172.4	-84.1	-52.2	0	0	0	112.7	E260 Y264 S286 I287 V288 G293 A294 F309	E260-N290 PolarHBondContact OE1-ND2 3.34Å; E260-N290 PolarHBondContact OE1-OD1 2.97Å; E260-N290 PolarHBondContact OE2-OD1 3.36Å; Y264-N290 PolarHBondContact OH-ND2 2.8Å; S286-N290 PolarHBondContact O-N 2.92Å; I287-N290 VanDerWaalsContact O-CB 3.31Å; I287-N290 WeakPolarHBondContact O-CB 3.45Å; I287-N290 PolarHBondContact O-N 3.09Å; V288-N290 VanDerWaalsContact C-N 3.31Å; V288-N290 PolarHBondContact O-N 3.42Å; N290-G293 PolarHBondContact O-N 3.28Å; N290-A294 WeakPolarHBondContact O-CB 3.49Å; N290-A294 PolarHBondContact O-N 3.42Å; N290-F309 WeakPolarHBondContact CB-O 3.49Å; N290-F309 WeakPolarHBondContact OD1-CD1 3.44Å
291	F	98.1	Very high	94.4	Very high	2 Å²	2	10.1 Å²	10.1	1%	0.009	8%	0.075	C	C	.	.	H	α-helix	trans	-68.1	-37	-178.7	-60.4	-44.5	0	0	0	112.6	I287 V288 A294 L295 F310 L314 A348 V351 A352 A355	I287-F291 HydrophobicContact CG2-CD2 3.93Å; I287-F291 HydrophobicContact CG2-CE2 3.39Å; I287-F291 HydrophobicContact CG2-CZ 4.1Å; I287-F291 WeakPolarHBondContact O-CD2 3.33Å; I287-F291 PolarHBondContact O-N 3.19Å; V288-F291 PolarHBondContact O-N 3.13Å; F291-A294 PolarHBondContact O-N 2.71Å; F291-L295 VanDerWaalsContact O-CB 3.26Å; F291-L295 WeakPolarHBondContact O-CB 3.27Å; F291-L295 PolarHBondContact O-N 3.22Å; F291-F310 AromaticContact CD1-CD2 3.84Å; F291-F310 HydrophobicContact CD1-CD2 3.84Å; F291-F310 HydrophobicContact CD1-CE2 4.04Å; F291-F310 HydrophobicContact CD1-CG 4.47Å; F291-F310 HydrophobicContact CE1-CD2 4.12Å; F291-F310 HydrophobicContact CE1-CE2 4.13Å; F291-F310 HydrophobicContact CE1-CG 4.48Å; F291-F310 HydrophobicContact CE1-CZ 4.5Å; F291-L314 HydrophobicContact CE1-CB 4.44Å; F291-A348 HydrophobicContact CD2-CB 4.42Å; F291-A348 WeakPolarHBondContact CD2-O 3.46Å; F291-A348 HydrophobicContact CE2-CB 4.18Å; F291-V351 HydrophobicContact CB-CB 4.11Å; F291-V351 HydrophobicContact CB-CG1 3.67Å; F291-A352 HydrophobicContact CD1-CB 3.96Å; F291-A352 HydrophobicContact CD2-CB 3.87Å; F291-A352 HydrophobicContact CE1-CB 3.96Å; F291-A352 HydrophobicContact CE2-CB 3.85Å; F291-A352 HydrophobicContact CG-CB 3.93Å; F291-A352 HydrophobicContact CZ-CB 3.9Å; F291-A355 WeakPolarHBondContact O-CB 3.13Å
292	A	97.7	Very high	95	Very high	0 Å²	0	11.2 Å²	11.2	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-64.6	-41.9	174.6	0	0	0	0	0	111.7	L230 F231 V288 G289 L295 L296 V351	L230-A292 HydrophobicContact CD1-CB 4.24Å; F231-A292 HydrophobicContact CD1-CB 4.3Å; F231-A292 HydrophobicContact CE1-CB 3.62Å; V288-A292 WeakPolarHBondContact O-CB 3.43Å; V288-A292 PolarHBondContact O-N 3.04Å; G289-A292 PolarHBondContact O-N 3.32Å; A292-L295 PolarHBondContact O-N 3.46Å; A292-L296 PolarHBondContact O-N 3.2Å; A292-V351 HydrophobicContact CB-CG1 4.46Å
293	G	98	Very high	95.3	Very high	0 Å²	0	18.9 Å²	18.9	0%	0	11%	0.112	C	C	.	.	H	α-helix	trans	-61.6	-47.7	173.8	0	0	0	0	0	111.9	W249 M253 G289 N290 L296 G297	W249-G293 PolarHBondContact NE1-O 3.36Å; M253-G293 WeakPolarHBondContact SD-CA 3.33Å; G289-G293 PolarHBondContact O-N 3.09Å; N290-G293 PolarHBondContact O-N 3.28Å; G293-L296 PolarHBondContact O-N 3.15Å; G293-G297 PolarHBondContact O-N 3.13Å
294	A	98.4	Very high	95.6	Very high	0 Å²	0	25.8 Å²	25.8	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-60.3	-45.5	175.4	0	0	0	0	0	111.9	N290 F291 L296 G297 A298 P306 F310 A355	N290-A294 WeakPolarHBondContact O-CB 3.49Å; N290-A294 PolarHBondContact O-N 3.42Å; F291-A294 PolarHBondContact O-N 2.71Å; A294-L296 PolarHBondContact O-N 3.49Å; A294-G297 PolarHBondContact O-N 3.43Å; A294-A298 VanDerWaalsContact O-CB 3.26Å; A294-A298 WeakPolarHBondContact O-CB 3.35Å; A294-A298 PolarHBondContact O-N 3.46Å; A294-P306 HydrophobicContact CB-CB 4.34Å; A294-P306 VanDerWaalsContact CB-O 3.29Å; A294-P306 WeakPolarHBondContact CB-O 3.4Å; A294-F310 HydrophobicContact CB-CB 4.02Å; A294-A355 HydrophobicContact CB-CB 4.28Å
295	L	97.8	Very high	95.8	Very high	14 Å²	14	26.5 Å²	26.5	7%	0.073	15%	0.153	C	C	.	.	H	α-helix	trans	-57.3	-48.4	176.2	175.7	57.6	0	0	0	111.8	L234 F291 A292 S299 V351 M354 A355 K358	L234-L295 HydrophobicContact CD1-CD2 3.83Å; L234-L295 HydrophobicContact CD1-CG 4.1Å; L234-L295 HydrophobicContact CD2-CD2 4.33Å; L234-L295 HydrophobicContact CD2-CG 3.91Å; F291-L295 VanDerWaalsContact O-CB 3.26Å; F291-L295 WeakPolarHBondContact O-CB 3.27Å; F291-L295 PolarHBondContact O-N 3.22Å; A292-L295 PolarHBondContact O-N 3.46Å; L295-S299 WeakPolarHBondContact O-CB 3.42Å; L295-S299 PolarHBondContact O-N 3.43Å; L295-S299 PolarHBondContact O-OG 2.97Å; L295-V351 HydrophobicContact CD2-CG1 4.49Å; L295-M354 HydrophobicContact CD1-CB 4.19Å; L295-M354 WeakPolarHBondContact CD1-O 3.29Å; L295-M354 HydrophobicContact CD2-CB 4.03Å; L295-M354 HydrophobicContact CD2-CE 4.27Å; L295-A355 HydrophobicContact CB-CB 3.88Å; L295-K358 HydrophobicContact CD1-CB 4.17Å; L295-K358 HydrophobicContact CD1-CG 3.52Å
296	L	97.2	Very high	96.1	Very high	1 Å²	1	26 Å²	26	1%	0.005	15%	0.15	C	C	.	.	H	α-helix	trans	-65.1	-47.7	178.7	-177.8	64.6	0	0	0	111.5	L230 A233 L234 L252 A292 G293 A294 A298 S299 M300	L230-L296 HydrophobicContact CD2-CB 4.42Å; L230-L296 HydrophobicContact CD2-CD2 3.39Å; A233-L296 HydrophobicContact CB-CD1 3.91Å; A233-L296 HydrophobicContact CB-CD2 3.91Å; L234-L296 HydrophobicContact CD2-CB 4.01Å; L234-L296 HydrophobicContact CD2-CD1 3.79Å; L234-L296 HydrophobicContact CG-CB 4.2Å; L234-L296 HydrophobicContact CG-CD1 3.98Å; L252-L296 HydrophobicContact CD1-CD2 4.43Å; A292-L296 PolarHBondContact O-N 3.2Å; G293-L296 PolarHBondContact O-N 3.15Å; A294-L296 PolarHBondContact O-N 3.49Å; L296-A298 PolarHBondContact O-N 3.09Å; L296-S299 WeakPolarHBondContact CA-OG 3.03Å; L296-S299 PolarHBondContact O-N 3.34Å; L296-S299 VanDerWaalsContact O-N 3.16Å; L296-S299 PolarHBondContact O-OG 3.4Å; L296-M300 HydrophobicContact CD1-CE 3.73Å; L296-M300 HydrophobicContact CD2-CE 3.99Å; L296-M300 HydrophobicContact CG-CE 3.79Å; L296-M300 WeakPolarHBondContact O-CG 3.43Å; L296-M300 PolarHBondContact O-N 3.01Å
297	G	97.2	Very high	96.3	Very high	0 Å²	0	29.7 Å²	29.7	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-64.7	-40.8	-177.6	0	0	0	0	0	112.5	W249 G293 A294 S299 M300 G301 L302	W249-G297 VanDerWaalsContact NE1-CA 3.26Å; G293-G297 PolarHBondContact O-N 3.13Å; A294-G297 PolarHBondContact O-N 3.43Å; G297-S299 VanDerWaalsContact C-N 3.31Å; G297-S299 PolarHBondContact O-N 3.41Å; G297-M300 CarbonylContact O-C 3.58Å; G297-M300 PolarHBondContact O-N 3.02Å; G297-M300 VanDerWaalsContact O-N 3.11Å; G297-G301 PolarHBondContact O-N 3.29Å; G297-L302 WeakPolarHBondContact O-CB 3.38Å; G297-L302 PolarHBondContact O-N 3.3Å
298	A	96.8	Very high	96.4	Very high	15 Å²	15	34.5 Å²	34.5	12%	0.124	19%	0.19	C	C	.	.	H	α-helix	trans	-64.6	-38.3	174.6	0	0	0	0	0	111.1	A294 L296 M300 G301 P306 K358 I359	A294-A298 VanDerWaalsContact O-CB 3.26Å; A294-A298 WeakPolarHBondContact O-CB 3.35Å; A294-A298 PolarHBondContact O-N 3.46Å; L296-A298 PolarHBondContact O-N 3.09Å; A298-M300 PolarHBondContact O-N 3.49Å; A298-G301 PolarHBondContact O-N 2.95Å; A298-P306 HydrophobicContact CB-CB 4.11Å; A298-P306 HydrophobicContact CB-CG 4.31Å; A298-P306 VanDerWaalsContact N-CG 3.27Å; A298-K358 HydrophobicContact CB-CB 3.7Å; A298-I359 HydrophobicContact CB-CG1 3.84Å
299	S	93.4	Very high	96.6	Very high	59 Å²	59	34.8 Å²	34.8	41%	0.413	19%	0.191	S	C	.	.	H	α-helix	trans	-65.8	-23.6	173.9	78.1	0	0	0	0	114	L295 L296 G297 G301	L295-S299 WeakPolarHBondContact O-CB 3.42Å; L295-S299 PolarHBondContact O-N 3.43Å; L295-S299 PolarHBondContact O-OG 2.97Å; L296-S299 WeakPolarHBondContact CA-OG 3.03Å; L296-S299 PolarHBondContact O-N 3.34Å; L296-S299 VanDerWaalsContact O-N 3.16Å; L296-S299 PolarHBondContact O-OG 3.4Å; G297-S299 VanDerWaalsContact C-N 3.31Å; G297-S299 PolarHBondContact O-N 3.41Å; S299-G301 VanDerWaalsContact C-N 3.33Å
300	M	93.4	Very high	96.7	Very high	32 Å²	32	35.6 Å²	35.6	16%	0.158	20%	0.195	C	C	.	.	T	Hydrogen-bonded Turn	trans	-86.2	-0.2	172.6	-66.5	-174.5	179	0	0	113.4	L244 W249 L296 G297 A298	L244-M300 HydrophobicContact CB-CE 3.49Å; L244-M300 VanDerWaalsContact CB-CE 3.49Å; L244-M300 HydrophobicContact CB-SD 4.41Å; L244-M300 HydrophobicContact CD1-CE 3.99Å; L244-M300 HydrophobicContact CG-CE 4.23Å; W249-M300 HydrophobicContact CB-SD 3.95Å; L296-M300 HydrophobicContact CD1-CE 3.73Å; L296-M300 HydrophobicContact CD2-CE 3.99Å; L296-M300 HydrophobicContact CG-CE 3.79Å; L296-M300 WeakPolarHBondContact O-CG 3.43Å; L296-M300 PolarHBondContact O-N 3.01Å; G297-M300 CarbonylContact O-C 3.58Å; G297-M300 PolarHBondContact O-N 3.02Å; G297-M300 VanDerWaalsContact O-N 3.11Å; A298-M300 PolarHBondContact O-N 3.49Å
301	G	92.7	Very high	96.7	Very high	58 Å²	58	38.2 Å²	38.2	60%	0.598	22%	0.216	S	C	*	.	T	Hydrogen-bonded Turn	trans	83.3	8.6	-179.2	0	0	0	0	0	115.2	G297 A298 S299	G297-G301 PolarHBondContact O-N 3.29Å; A298-G301 PolarHBondContact O-N 2.95Å; S299-G301 VanDerWaalsContact C-N 3.33Å
302	L	95.3	Very high	96.7	Very high	32 Å²	32	39.8 Å²	39.8	17%	0.168	22%	0.224	C	C	.	.			trans	-71.1	144	170.7	-62	175	0	0	0	109.8	W249 Y250 G297 P306	W249-L302 HydrophobicContact CB-CD1 3.92Å; W249-L302 HydrophobicContact CD2-CD1 3.58Å; W249-L302 HydrophobicContact CE3-CD1 3.59Å; W249-L302 HydrophobicContact CG-CD1 3.75Å; W249-L302 HydrophobicContact CZ3-CD1 4.33Å; Y250-L302 HydrophobicContact CE2-CD1 4.3Å; Y250-L302 HydrophobicContact CE2-CD2 4.39Å; G297-L302 WeakPolarHBondContact O-CB 3.38Å; G297-L302 PolarHBondContact O-N 3.3Å; L302-P306 HydrophobicContact CB-CG 3.9Å; L302-P306 WeakPolarHBondContact O-CG 3.15Å
303	K	93.3	Very high	96.6	Very high	166 Å²	166	39.8 Å²	39.8	72%	0.722	22%	0.224	S	C	*	.			trans	-104.9	-71.5	-177	-62.2	-174.3	178.5	-176.3	0	112.4	P306 I307	K303-P306 WeakPolarHBondContact O-CD 3.21Å; K303-I307 WeakPolarHBondContact O-CD1 3.4Å; K303-I307 WeakPolarHBondContact O-CG1 3.14Å; K303-I307 PolarHBondContact O-N 3.31Å
304	E	95.9	Very high	96.6	Very high	146 Å²	146	43.4 Å²	43.4	68%	0.682	24%	0.243	S	C	*	.	H	α-helix	trans	-67.2	-42.3	-171.5	-60.4	-55.6	147.3	0	0	113.9	I307 F308	E304-I307 PolarHBondContact O-N 3.07Å; E304-F308 WeakPolarHBondContact O-CB 3.16Å; E304-F308 PolarHBondContact O-N 3.34Å
305	G	96.4	Very high	96.5	Very high	17 Å²	17	45.9 Å²	45.9	18%	0.175	26%	0.263	C	S	.	.	H	α-helix	trans	-57.6	-51.8	-179.3	0	0	0	0	0	113.3	I307 F308 F309	G305-I307 VanDerWaalsContact C-N 3.34Å; G305-I307 PolarHBondContact O-N 2.82Å; G305-F308 WeakPolarHBondContact O-CB 3.27Å; G305-F308 PolarHBondContact O-N 2.69Å; G305-F309 WeakPolarHBondContact O-CD2 3.38Å; G305-F309 PolarHBondContact O-N 2.92Å; G305-F309 VanDerWaalsContact O-N 3.15Å
306	P	97.8	Very high	96.4	Very high	1 Å²	1	47.3 Å²	47.3	1%	0.006	27%	0.268	C	S	.	.	H	α-helix	trans	-55.7	-42.9	173.1	-33.1	39.9	0	0	0	114.6	W249 A294 A298 L302 K303 F308 F309 F310 I359	W249-P306 HydrophobicContact CZ2-CG 4.44Å; A294-P306 HydrophobicContact CB-CB 4.34Å; A294-P306 VanDerWaalsContact CB-O 3.29Å; A294-P306 WeakPolarHBondContact CB-O 3.4Å; A298-P306 HydrophobicContact CB-CB 4.11Å; A298-P306 HydrophobicContact CB-CG 4.31Å; A298-P306 VanDerWaalsContact N-CG 3.27Å; L302-P306 HydrophobicContact CB-CG 3.9Å; L302-P306 WeakPolarHBondContact O-CG 3.15Å; K303-P306 WeakPolarHBondContact O-CD 3.21Å; P306-F308 VanDerWaalsContact C-N 3.35Å; P306-F309 PolarHBondContact O-N 3.42Å; P306-F310 VanDerWaalsContact O-CB 3.24Å; P306-F310 WeakPolarHBondContact O-CB 3.37Å; P306-F310 PolarHBondContact O-N 3.13Å; P306-I359 HydrophobicContact CB-CD1 4.44Å; P306-I359 HydrophobicContact CB-CG1 4.35Å
307	I	98	Very high	96.3	Very high	77 Å²	77	48 Å²	48	40%	0.395	27%	0.271	S	S	.	.	H	α-helix	trans	-63.9	-42.6	178.8	-65.9	168.2	0	0	0	110.5	K303 E304 G305 F310 A311 I359	K303-I307 WeakPolarHBondContact O-CD1 3.4Å; K303-I307 WeakPolarHBondContact O-CG1 3.14Å; K303-I307 PolarHBondContact O-N 3.31Å; E304-I307 PolarHBondContact O-N 3.07Å; G305-I307 VanDerWaalsContact C-N 3.34Å; G305-I307 PolarHBondContact O-N 2.82Å; I307-F310 PolarHBondContact O-N 2.95Å; I307-A311 WeakPolarHBondContact O-CB 3.08Å; I307-A311 PolarHBondContact O-N 2.88Å; I307-I359 HydrophobicContact CD1-CG2 4.4Å; I307-I359 HydrophobicContact CG1-CG2 3.91Å
308	F	98.3	Very high	96.2	Very high	101 Å²	101	52.7 Å²	52.7	44%	0.443	30%	0.295	S	S	.	.	H	α-helix	trans	-57.3	-53.1	176.4	170.4	-96.3	0	0	0	112.3	L257 E304 G305 P306 F310 A311 I312	L257-F308 HydrophobicContact CD1-CE1 4.07Å; L257-F308 HydrophobicContact CD1-CZ 4.3Å; E304-F308 WeakPolarHBondContact O-CB 3.16Å; E304-F308 PolarHBondContact O-N 3.34Å; G305-F308 WeakPolarHBondContact O-CB 3.27Å; G305-F308 PolarHBondContact O-N 2.69Å; P306-F308 VanDerWaalsContact C-N 3.35Å; F308-F310 VanDerWaalsContact C-N 3.35Å; F308-F310 PolarHBondContact O-N 3.3Å; F308-A311 PolarHBondContact O-N 3.49Å; F308-I312 HydrophobicContact CD1-CD1 3.98Å; F308-I312 HydrophobicContact CD2-CD1 4.26Å; F308-I312 HydrophobicContact CE1-CD1 3.4Å; F308-I312 HydrophobicContact CE2-CD1 3.73Å; F308-I312 HydrophobicContact CG-CD1 4.39Å; F308-I312 HydrophobicContact CZ-CD1 3.27Å; F308-I312 WeakPolarHBondContact O-CG1 3.34Å; F308-I312 PolarHBondContact O-N 2.74Å; F308-I312 VanDerWaalsContact O-N 3.08Å
309	F	98.3	Very high	96	Very high	9 Å²	9	55.5 Å²	55.5	4%	0.039	31%	0.311	C	S	.	.	H	α-helix	trans	-68.7	-33.8	179.2	-76.1	-71.8	0	0	0	112.3	W249 M253 L257 N290 G305 P306 I312 G313	W249-F309 AromaticContact CH2-CD2 3.53Å; W249-F309 HydrophobicContact CH2-CD2 3.53Å; W249-F309 AromaticContact CH2-CE2 3.46Å; W249-F309 HydrophobicContact CH2-CE2 3.46Å; W249-F309 VanDerWaalsContact CH2-CE2 3.46Å; W249-F309 AromaticContact CZ2-CD2 3.58Å; W249-F309 HydrophobicContact CZ2-CD2 3.58Å; W249-F309 AromaticContact CZ2-CE2 3.86Å; W249-F309 HydrophobicContact CZ2-CE2 3.86Å; W249-F309 HydrophobicContact CZ3-CE2 4.31Å; M253-F309 HydrophobicContact CB-CE2 3.7Å; M253-F309 HydrophobicContact CB-CZ 3.74Å; M253-F309 HydrophobicContact CE-CB 4.29Å; M253-F309 HydrophobicContact CE-CD1 3.43Å; M253-F309 VanDerWaalsContact CE-CD1 3.43Å; M253-F309 HydrophobicContact CE-CD2 3.64Å; M253-F309 HydrophobicContact CE-CE1 3.44Å; M253-F309 VanDerWaalsContact CE-CE1 3.44Å; M253-F309 HydrophobicContact CE-CE2 3.67Å; M253-F309 HydrophobicContact CE-CG 3.52Å; M253-F309 HydrophobicContact CE-CZ 3.57Å; M253-F309 HydrophobicContact CG-CD2 4.44Å; M253-F309 HydrophobicContact CG-CE2 4.02Å; M253-F309 HydrophobicContact CG-CZ 4.37Å; L257-F309 HydrophobicContact CB-CE1 4.1Å; L257-F309 HydrophobicContact CB-CZ 4.08Å; L257-F309 HydrophobicContact CD1-CE1 4.12Å; L257-F309 HydrophobicContact CD1-CZ 4.47Å; N290-F309 WeakPolarHBondContact CB-O 3.49Å; N290-F309 WeakPolarHBondContact OD1-CD1 3.44Å; G305-F309 WeakPolarHBondContact O-CD2 3.38Å; G305-F309 PolarHBondContact O-N 2.92Å; G305-F309 VanDerWaalsContact O-N 3.15Å; P306-F309 PolarHBondContact O-N 3.42Å; F309-I312 PolarHBondContact O-N 3.06Å; F309-G313 PolarHBondContact O-N 2.9Å
310	F	98.3	Very high	95.9	Very high	18 Å²	18	52.7 Å²	52.7	8%	0.079	29%	0.291	C	S	.	.	H	α-helix	trans	-61.2	-45.5	172.9	-172.5	-85	0	0	0	111.6	F291 A294 P306 I307 F308 G313 L314 A352 A355 W356 I359	F291-F310 AromaticContact CD1-CD2 3.84Å; F291-F310 HydrophobicContact CD1-CD2 3.84Å; F291-F310 HydrophobicContact CD1-CE2 4.04Å; F291-F310 HydrophobicContact CD1-CG 4.47Å; F291-F310 HydrophobicContact CE1-CD2 4.12Å; F291-F310 HydrophobicContact CE1-CE2 4.13Å; F291-F310 HydrophobicContact CE1-CG 4.48Å; F291-F310 HydrophobicContact CE1-CZ 4.5Å; A294-F310 HydrophobicContact CB-CB 4.02Å; P306-F310 VanDerWaalsContact O-CB 3.24Å; P306-F310 WeakPolarHBondContact O-CB 3.37Å; P306-F310 PolarHBondContact O-N 3.13Å; I307-F310 PolarHBondContact O-N 2.95Å; F308-F310 VanDerWaalsContact C-N 3.35Å; F308-F310 PolarHBondContact O-N 3.3Å; F310-G313 PolarHBondContact O-N 3.03Å; F310-L314 HydrophobicContact CE1-CD2 4.32Å; F310-L314 WeakPolarHBondContact O-CB 3.3Å; F310-L314 PolarHBondContact O-N 3.3Å; F310-A352 HydrophobicContact CE2-CB 4.13Å; F310-A352 WeakPolarHBondContact CE2-O 3.26Å; F310-A352 HydrophobicContact CZ-CB 4.44Å; F310-A355 HydrophobicContact CD2-CB 4.01Å; F310-A355 HydrophobicContact CE2-CB 4.17Å; F310-W356 AromaticContact CD1-CE3 3.79Å; F310-W356 HydrophobicContact CD1-CE3 3.79Å; F310-W356 AromaticContact CD1-CZ3 3.86Å; F310-W356 HydrophobicContact CD1-CZ3 3.86Å; F310-W356 HydrophobicContact CD2-CE3 4.42Å; F310-W356 HydrophobicContact CE1-CD2 4.35Å; F310-W356 AromaticContact CE1-CE3 3.28Å; F310-W356 HydrophobicContact CE1-CE3 3.28Å; F310-W356 AromaticContact CE1-CZ3 3.56Å; F310-W356 HydrophobicContact CE1-CZ3 3.56Å; F310-W356 HydrophobicContact CE2-CB 3.99Å; F310-W356 AromaticContact CE2-CE3 3.98Å; F310-W356 HydrophobicContact CE2-CE3 3.98Å; F310-W356 HydrophobicContact CG-CE3 4.34Å; F310-W356 HydrophobicContact CZ-CB 4.06Å; F310-W356 HydrophobicContact CZ-CD2 4.13Å; F310-W356 AromaticContact CZ-CE3 3.4Å; F310-W356 HydrophobicContact CZ-CE3 3.4Å; F310-W356 HydrophobicContact CZ-CG 4.43Å; F310-W356 HydrophobicContact CZ-CZ3 4.16Å; F310-I359 HydrophobicContact CB-CD1 3.96Å; F310-I359 HydrophobicContact CD2-CD1 4.02Å; F310-I359 HydrophobicContact CG-CD1 4.05Å
311	A	98.2	Very high	95.7	Very high	54 Å²	54	53.5 Å²	53.5	45%	0.446	29%	0.294	S	S	.	.	H	α-helix	trans	-63	-44.2	179.1	0	0	0	0	0	112.1	I307 F308 L314 A315	I307-A311 WeakPolarHBondContact O-CB 3.08Å; I307-A311 PolarHBondContact O-N 2.88Å; F308-A311 PolarHBondContact O-N 3.49Å; A311-L314 PolarHBondContact O-N 3.47Å; A311-A315 WeakPolarHBondContact O-CB 3.31Å; A311-A315 PolarHBondContact O-N 3.42Å
312	I	97.6	Very high	95.5	Very high	35 Å²	35	54.1 Å²	54.1	18%	0.179	29%	0.286	C	S	.	.	H	α-helix	trans	-61.2	-49.5	174.5	-68.8	174.3	0	0	0	110.4	Y264 F308 F309 L314 A315 Y316	Y264-I312 HydrophobicContact CD2-CG2 4.25Å; Y264-I312 HydrophobicContact CE2-CG2 3.77Å; F308-I312 HydrophobicContact CD1-CD1 3.98Å; F308-I312 HydrophobicContact CD2-CD1 4.26Å; F308-I312 HydrophobicContact CE1-CD1 3.4Å; F308-I312 HydrophobicContact CE2-CD1 3.73Å; F308-I312 HydrophobicContact CG-CD1 4.39Å; F308-I312 HydrophobicContact CZ-CD1 3.27Å; F308-I312 WeakPolarHBondContact O-CG1 3.34Å; F308-I312 PolarHBondContact O-N 2.74Å; F308-I312 VanDerWaalsContact O-N 3.08Å; F309-I312 PolarHBondContact O-N 3.06Å; I312-L314 VanDerWaalsContact C-N 3.29Å; I312-L314 PolarHBondContact O-N 3.03Å; I312-A315 PolarHBondContact O-N 2.89Å; I312-Y316 HydrophobicContact CG2-CD2 3.93Å; I312-Y316 HydrophobicContact CG2-CE2 4.28Å; I312-Y316 WeakPolarHBondContact O-CD2 3.46Å; I312-Y316 PolarHBondContact O-N 3.37Å
313	G	97.5	Very high	95.1	Very high	0 Å²	0	53.8 Å²	53.8	0%	0	29%	0.285	C	S	.	.	H	α-helix	trans	-55.5	-44	177.6	0	0	0	0	0	112.3	F309 F310 Y317	F309-G313 PolarHBondContact O-N 2.9Å; F310-G313 PolarHBondContact O-N 3.03Å; G313-Y317 WeakPolarHBondContact O-CB 3.41Å; G313-Y317 PolarHBondContact O-N 2.65Å
314	L	97.2	Very high	94.7	Very high	77 Å²	77	46.3 Å²	46.3	40%	0.403	25%	0.253	S	S	.	.	H	α-helix	trans	-66.8	-45.9	178.9	-176.4	64	0	0	0	112.4	F291 F310 A311 I312 Y317 L318	F291-L314 HydrophobicContact CE1-CB 4.44Å; F310-L314 HydrophobicContact CE1-CD2 4.32Å; F310-L314 WeakPolarHBondContact O-CB 3.3Å; F310-L314 PolarHBondContact O-N 3.3Å; A311-L314 PolarHBondContact O-N 3.47Å; I312-L314 VanDerWaalsContact C-N 3.29Å; I312-L314 PolarHBondContact O-N 3.03Å; L314-Y317 WeakPolarHBondContact O-CB 3.11Å; L314-Y317 PolarHBondContact O-N 3.16Å; L314-L318 WeakPolarHBondContact O-CG 3.29Å; L314-L318 PolarHBondContact O-N 3.45Å
315	A	96.8	Very high	93.8	Very high	51 Å²	51	45.1 Å²	45.1	42%	0.421	24%	0.243	S	C	.	.	H	α-helix	trans	-60.2	-49.3	178.9	0	0	0	0	0	111.4	A311 I312 L318 V319	A311-A315 WeakPolarHBondContact O-CB 3.31Å; A311-A315 PolarHBondContact O-N 3.42Å; I312-A315 PolarHBondContact O-N 2.89Å; A315-L318 PolarHBondContact O-N 3.11Å; A315-V319 WeakPolarHBondContact O-CG2 3.46Å; A315-V319 PolarHBondContact O-N 3.47Å; A315-V319 VanDerWaalsContact O-N 3.15Å
316	Y	95.1	Very high	93	Very high	44 Å²	44	51.5 Å²	51.5	17%	0.173	27%	0.268	C	S	.	.	H	α-helix	trans	-73.8	-26.2	179.4	-78.8	-82	0	0	0	113.2	Y264 W267 M268 I312 L320	Y264-Y316 AromaticContact CD1-CD1 3.94Å; Y264-Y316 HydrophobicContact CD1-CD1 3.94Å; Y264-Y316 HydrophobicContact CD1-CE1 4.06Å; Y264-Y316 HydrophobicContact CD1-CG 4.32Å; Y264-Y316 AromaticContact CD2-CD1 3.94Å; Y264-Y316 HydrophobicContact CD2-CD1 3.94Å; Y264-Y316 AromaticContact CD2-CD2 3.39Å; Y264-Y316 HydrophobicContact CD2-CD2 3.39Å; Y264-Y316 AromaticContact CD2-CE1 3.87Å; Y264-Y316 HydrophobicContact CD2-CE1 3.87Å; Y264-Y316 AromaticContact CD2-CE2 3.29Å; Y264-Y316 HydrophobicContact CD2-CE2 3.29Å; Y264-Y316 AromaticContact CD2-CG 3.71Å; Y264-Y316 HydrophobicContact CD2-CG 3.71Å; Y264-Y316 AromaticContact CD2-CZ 3.55Å; Y264-Y316 HydrophobicContact CE1-CD1 4.15Å; Y264-Y316 HydrophobicContact CE1-CG 4.19Å; Y264-Y316 HydrophobicContact CE2-CD1 4.12Å; Y264-Y316 AromaticContact CE2-CD2 3.36Å; Y264-Y316 HydrophobicContact CE2-CD2 3.36Å; Y264-Y316 HydrophobicContact CE2-CE1 4.5Å; Y264-Y316 AromaticContact CE2-CE2 3.8Å; Y264-Y316 HydrophobicContact CE2-CE2 3.8Å; Y264-Y316 AromaticContact CE2-CG 3.53Å; Y264-Y316 HydrophobicContact CE2-CG 3.53Å; Y264-Y316 AromaticContact CG-CD1 3.84Å; Y264-Y316 HydrophobicContact CG-CD1 3.84Å; Y264-Y316 HydrophobicContact CG-CD2 4.14Å; Y264-Y316 AromaticContact CG-CE1 3.6Å; Y264-Y316 HydrophobicContact CG-CE1 3.6Å; Y264-Y316 AromaticContact CG-CE2 3.91Å; Y264-Y316 HydrophobicContact CG-CE2 3.91Å; Y264-Y316 HydrophobicContact CG-CG 4.1Å; Y264-Y316 AromaticContact CG-CZ 3.64Å; Y264-Y316 AromaticContact CZ-CG 3.79Å; W267-Y316 AromaticContact CE3-CD1 3.82Å; W267-Y316 HydrophobicContact CE3-CD1 3.82Å; W267-Y316 HydrophobicContact CE3-CE1 4.11Å; W267-Y316 AromaticContact CZ3-CD1 3.9Å; W267-Y316 HydrophobicContact CZ3-CD1 3.9Å; M268-Y316 PolarHBondContact SD-OH 3.46Å; I312-Y316 HydrophobicContact CG2-CD2 3.93Å; I312-Y316 HydrophobicContact CG2-CE2 4.28Å; I312-Y316 WeakPolarHBondContact O-CD2 3.46Å; I312-Y316 PolarHBondContact O-N 3.37Å; Y316-L320 WeakPolarHBondContact O-CB 3.19Å; Y316-L320 PolarHBondContact O-N 3.01Å
317	Y	95.4	Very high	91.8	Very high	17 Å²	17	56.9 Å²	56.9	7%	0.067	29%	0.289	C	S	.	.	H	α-helix	trans	-59.1	-51.8	168.3	174.7	-107.8	0	0	0	111.1	I287 G313 L314 V319 L320 F321 A348	I287-Y317 HydrophobicContact CG2-CD2 4.28Å; G313-Y317 WeakPolarHBondContact O-CB 3.41Å; G313-Y317 PolarHBondContact O-N 2.65Å; L314-Y317 WeakPolarHBondContact O-CB 3.11Å; L314-Y317 PolarHBondContact O-N 3.16Å; Y317-V319 PolarHBondContact O-N 3.19Å; Y317-L320 PolarHBondContact O-N 3.41Å; Y317-F321 HydrophobicContact CE2-CD2 4.27Å; Y317-F321 AromaticContact CZ-CD2 3.98Å; Y317-F321 WeakPolarHBondContact O-CB 3.38Å; Y317-F321 PolarHBondContact O-N 2.85Å; Y317-A348 HydrophobicContact CD2-CB 3.81Å; Y317-A348 HydrophobicContact CE2-CB 3.89Å
318	L	94.1	Very high	90.2	Very high	98 Å²	98	55.6 Å²	55.6	51%	0.513	28%	0.282	S	S	.	.	H	α-helix	trans	-61	-45.7	-179.8	-68.7	174.2	0	0	0	111.7	L314 A315 L320 F321 V322	L314-L318 WeakPolarHBondContact O-CG 3.29Å; L314-L318 PolarHBondContact O-N 3.45Å; A315-L318 PolarHBondContact O-N 3.11Å; L318-L320 PolarHBondContact O-N 2.95Å; L318-F321 PolarHBondContact O-N 3.47Å; L318-V322 WeakPolarHBondContact O-CG2 3.47Å; L318-V322 PolarHBondContact O-N 2.95Å
319	V	92.7	Very high	88.2	Confident	73 Å²	73	53.5 Å²	53.5	44%	0.442	28%	0.279	S	S	.	.	H	α-helix	trans	-60.5	-47.7	177.6	173	0	0	0	0	111.1	L275 A315 Y317 T323	L275-V319 HydrophobicContact CD2-CG1 3.63Å; A315-V319 WeakPolarHBondContact O-CG2 3.46Å; A315-V319 PolarHBondContact O-N 3.47Å; A315-V319 VanDerWaalsContact O-N 3.15Å; Y317-V319 PolarHBondContact O-N 3.19Å; V319-T323 VanDerWaalsContact O-CB 3.28Å; V319-T323 WeakPolarHBondContact O-CB 2.95Å; V319-T323 PolarHBondContact O-N 2.9Å; V319-T323 PolarHBondContact O-OG1 2.99Å
320	L	91	Very high	86	Confident	0 Å²	0	59.4 Å²	59.4	0%	0	32%	0.316	C	S	.	.	H	α-helix	trans	-67.8	-41.8	-179.6	-176.2	68.7	0	0	0	111.6	L275 A279 N283 I287 Y316 Y317 L318 T323 L324	L275-L320 HydrophobicContact CD1-CD1 3.87Å; A279-L320 HydrophobicContact CB-CD1 4.48Å; N283-L320 HydrophobicContact CB-CD1 3.79Å; N283-L320 HydrophobicContact CB-CD2 3.61Å; N283-L320 HydrophobicContact CB-CG 4.39Å; I287-L320 HydrophobicContact CD1-CB 3.88Å; I287-L320 HydrophobicContact CD1-CD2 3.35Å; I287-L320 HydrophobicContact CD1-CG 4.24Å; Y316-L320 WeakPolarHBondContact O-CB 3.19Å; Y316-L320 PolarHBondContact O-N 3.01Å; Y317-L320 PolarHBondContact O-N 3.41Å; L318-L320 PolarHBondContact O-N 2.95Å; L320-T323 PolarHBondContact O-N 3.2Å; L320-L324 HydrophobicContact CD1-CD1 3.9Å; L320-L324 HydrophobicContact CD1-CG 4.01Å; L320-L324 HydrophobicContact CD2-CD1 4.15Å; L320-L324 HydrophobicContact CG-CD1 3.68Å; L320-L324 HydrophobicContact CG-CG 4.17Å; L320-L324 WeakPolarHBondContact O-CB 3.18Å; L320-L324 VanDerWaalsContact O-CG 3.3Å; L320-L324 WeakPolarHBondContact O-CG 3.32Å; L320-L324 PolarHBondContact O-N 3.24Å
321	F	89.3	Confident	83.2	Confident	49 Å²	49	66 Å²	66	22%	0.215	35%	0.352	C	S	.	.	H	α-helix	trans	-58.4	-53.5	179.4	-174	-96.6	0	0	0	110.4	Y317 L318 T323 L324 Y325 F345 L377	Y317-F321 HydrophobicContact CE2-CD2 4.27Å; Y317-F321 AromaticContact CZ-CD2 3.98Å; Y317-F321 WeakPolarHBondContact O-CB 3.38Å; Y317-F321 PolarHBondContact O-N 2.85Å; L318-F321 PolarHBondContact O-N 3.47Å; F321-T323 PolarHBondContact O-N 2.77Å; F321-L324 PolarHBondContact O-N 3.19Å; F321-Y325 HydrophobicContact CD1-CD2 4.29Å; F321-Y325 HydrophobicContact CD1-CE2 4.45Å; F321-Y325 HydrophobicContact CD2-CD2 4.37Å; F321-Y325 HydrophobicContact CD2-CE2 4.07Å; F321-Y325 HydrophobicContact CE1-CD2 4.04Å; F321-Y325 AromaticContact CE1-CE2 3.88Å; F321-Y325 HydrophobicContact CE1-CE2 3.88Å; F321-Y325 HydrophobicContact CE2-CD2 4.14Å; F321-Y325 AromaticContact CE2-CE2 3.45Å; F321-Y325 HydrophobicContact CE2-CE2 3.45Å; F321-Y325 VanDerWaalsContact CE2-CE2 3.45Å; F321-Y325 HydrophobicContact CG-CD2 4.44Å; F321-Y325 AromaticContact CZ-CD2 3.96Å; F321-Y325 HydrophobicContact CZ-CD2 3.96Å; F321-Y325 AromaticContact CZ-CE2 3.33Å; F321-Y325 HydrophobicContact CZ-CE2 3.33Å; F321-Y325 AromaticContact CZ-CZ 3.78Å; F321-Y325 WeakPolarHBondContact O-CD2 3.12Å; F321-Y325 PolarHBondContact O-N 3.45Å; F321-F345 AromaticContact CD2-CD1 3.82Å; F321-F345 HydrophobicContact CD2-CD1 3.82Å; F321-F345 HydrophobicContact CD2-CE1 4.13Å; F321-F345 HydrophobicContact CE2-CD1 4.03Å; F321-F345 HydrophobicContact CE2-CE1 4.5Å; F321-L377 HydrophobicContact CE2-CD1 4.22Å; F321-L377 HydrophobicContact CE2-CD2 4.28Å
322	V	89.4	Confident	80.9	Confident	71 Å²	71	70.7 Å²	70.7	43%	0.43	37%	0.365	S	S	.	.	H	α-helix	trans	-60.6	-47	177	173.8	0	0	0	0	111	L318 L324 Y325 Q326	L318-V322 WeakPolarHBondContact O-CG2 3.47Å; L318-V322 PolarHBondContact O-N 2.95Å; V322-L324 VanDerWaalsContact C-N 3.35Å; V322-L324 PolarHBondContact O-N 3.01Å; V322-Y325 PolarHBondContact O-N 3.09Å; V322-Q326 HydrophobicContact CG1-CG 4.36Å; V322-Q326 WeakPolarHBondContact O-CG 3.39Å; V322-Q326 PolarHBondContact O-N 3.15Å
323	T	87.8	Confident	78.5	Confident	26 Å²	26	75.1 Å²	75.1	16%	0.16	39%	0.393	C	S	.	.	H	α-helix	trans	-60.8	-44.2	-178.2	-58.3	0	0	0	0	111.7	L275 A279 V319 L320 F321 Q326 R327	L275-T323 HydrophobicContact CG-CG2 4.22Å; A279-T323 HydrophobicContact CB-CG2 3.83Å; V319-T323 VanDerWaalsContact O-CB 3.28Å; V319-T323 WeakPolarHBondContact O-CB 2.95Å; V319-T323 PolarHBondContact O-N 2.9Å; V319-T323 PolarHBondContact O-OG1 2.99Å; L320-T323 PolarHBondContact O-N 3.2Å; F321-T323 PolarHBondContact O-N 2.77Å; T323-Q326 PolarHBondContact O-N 2.96Å; T323-R327 VanDerWaalsContact O-CB 3.27Å; T323-R327 WeakPolarHBondContact O-CB 3.2Å; T323-R327 PolarHBondContact O-N 3.05Å
324	L	83.9	Confident	76.2	Confident	9 Å²	9	77.3 Å²	77.3	5%	0.047	41%	0.405	C	S	.	.	H	α-helix	trans	-65.7	-44.4	179.1	-71.6	170.7	0	0	0	110.8	A279 H284 L320 F321 V322 Q326 R327 L328 F345	A279-L324 HydrophobicContact CB-CD2 3.91Å; H284-L324 VanDerWaalsContact CE1-CD1 3.47Å; H284-L324 WeakPolarHBondContact CE1-CD1 3.25Å; L320-L324 HydrophobicContact CD1-CD1 3.9Å; L320-L324 HydrophobicContact CD1-CG 4.01Å; L320-L324 HydrophobicContact CD2-CD1 4.15Å; L320-L324 HydrophobicContact CG-CD1 3.68Å; L320-L324 HydrophobicContact CG-CG 4.17Å; L320-L324 WeakPolarHBondContact O-CB 3.18Å; L320-L324 VanDerWaalsContact O-CG 3.3Å; L320-L324 WeakPolarHBondContact O-CG 3.32Å; L320-L324 PolarHBondContact O-N 3.24Å; F321-L324 PolarHBondContact O-N 3.19Å; V322-L324 VanDerWaalsContact C-N 3.35Å; V322-L324 PolarHBondContact O-N 3.01Å; L324-Q326 VanDerWaalsContact C-N 3.27Å; L324-Q326 PolarHBondContact O-N 3.43Å; L324-R327 PolarHBondContact O-N 3.12Å; L324-R327 VanDerWaalsContact O-N 3.08Å; L324-L328 WeakPolarHBondContact O-CG 3.41Å; L324-L328 PolarHBondContact O-N 2.62Å; L324-F345 HydrophobicContact CB-CE1 4Å; L324-F345 HydrophobicContact CB-CZ 3.63Å; L324-F345 HydrophobicContact CD1-CE1 3.75Å; L324-F345 HydrophobicContact CD1-CE2 4.04Å; L324-F345 HydrophobicContact CD1-CZ 3.33Å; L324-F345 HydrophobicContact CG-CZ 4.07Å
325	Y	77.1	Confident	74	Confident	121 Å²	121	77.1 Å²	77.1	48%	0.475	41%	0.408	S	S	.	.	H	α-helix	trans	-59.7	-36.4	176.7	-93.5	-101.9	0	0	0	113.2	F321 V322 F345	F321-Y325 HydrophobicContact CD1-CD2 4.29Å; F321-Y325 HydrophobicContact CD1-CE2 4.45Å; F321-Y325 HydrophobicContact CD2-CD2 4.37Å; F321-Y325 HydrophobicContact CD2-CE2 4.07Å; F321-Y325 HydrophobicContact CE1-CD2 4.04Å; F321-Y325 AromaticContact CE1-CE2 3.88Å; F321-Y325 HydrophobicContact CE1-CE2 3.88Å; F321-Y325 HydrophobicContact CE2-CD2 4.14Å; F321-Y325 AromaticContact CE2-CE2 3.45Å; F321-Y325 HydrophobicContact CE2-CE2 3.45Å; F321-Y325 VanDerWaalsContact CE2-CE2 3.45Å; F321-Y325 HydrophobicContact CG-CD2 4.44Å; F321-Y325 AromaticContact CZ-CD2 3.96Å; F321-Y325 HydrophobicContact CZ-CD2 3.96Å; F321-Y325 AromaticContact CZ-CE2 3.33Å; F321-Y325 HydrophobicContact CZ-CE2 3.33Å; F321-Y325 AromaticContact CZ-CZ 3.78Å; F321-Y325 WeakPolarHBondContact O-CD2 3.12Å; F321-Y325 PolarHBondContact O-N 3.45Å; V322-Y325 PolarHBondContact O-N 3.09Å; Y325-F345 HydrophobicContact CD2-CE1 4.3Å; Y325-F345 HydrophobicContact CE2-CD1 4.47Å; Y325-F345 HydrophobicContact CE2-CE1 4.12Å
326	Q	80.3	Confident	71.7	Confident	150 Å²	150	81 Å²	81	70%	0.701	42%	0.416	S	S	*	.	H	α-helix	trans	-74.4	-25.1	176.3	-71.3	175.6	-11.8	0	0	113.6	V322 T323 L324	V322-Q326 HydrophobicContact CG1-CG 4.36Å; V322-Q326 WeakPolarHBondContact O-CG 3.39Å; V322-Q326 PolarHBondContact O-N 3.15Å; T323-Q326 PolarHBondContact O-N 2.96Å; L324-Q326 VanDerWaalsContact C-N 3.27Å; L324-Q326 PolarHBondContact O-N 3.43Å
327	R	71.8	Confident	69.5	Low	114 Å²	114	84 Å²	84	43%	0.43	43%	0.431	S	S	.	.	H	α-helix	trans	-98.5	-14.8	-173.5	-150.1	-171.1	-177.1	-146	-0.3	113.7	S276 K277 A279 T323 L324 P329	S276-R327 PolarHBondContact O-NE 2.79Å; S276-R327 PolarHBondContact O-NH2 2.79Å; K277-R327 VanDerWaalsContact C-NH1 3.35Å; K277-R327 PolarHBondContact O-NH1 3.46Å; K277-R327 PolarHBondContact O-NH2 3.02Å; A279-R327 PolarHBondContact O-NH1 3.27Å; T323-R327 VanDerWaalsContact O-CB 3.27Å; T323-R327 WeakPolarHBondContact O-CB 3.2Å; T323-R327 PolarHBondContact O-N 3.05Å; L324-R327 PolarHBondContact O-N 3.12Å; L324-R327 VanDerWaalsContact O-N 3.08Å; R327-P329 WeakPolarHBondContact O-CD 3.36Å; R327-P329 VanDerWaalsContact O-N 3.09Å
328	L	64	Low	67.3	Low	51 Å²	51	84.5 Å²	84.5	27%	0.267	44%	0.435	S	S	.	.	S	Bend	trans	-55	120.8	172.3	-71.7	166	0	0	0	107.1	L324 T330 L334 F342	L324-L328 WeakPolarHBondContact O-CG 3.41Å; L324-L328 PolarHBondContact O-N 2.62Å; L328-T330 PolarHBondContact O-N 3.01Å; L328-L334 HydrophobicContact CB-CD1 4.45Å; L328-L334 HydrophobicContact CD2-CD1 3.51Å; L328-L334 HydrophobicContact CD2-CD2 3.82Å; L328-L334 HydrophobicContact CD2-CG 4.25Å; L328-L334 HydrophobicContact CG-CD1 4.46Å; L328-F342 HydrophobicContact CD1-CE1 4.33Å; L328-F342 HydrophobicContact CD2-CE1 3.52Å; L328-F342 HydrophobicContact CD2-CZ 3.53Å
329	P	56.8	Low	65.8	Low	56 Å²	56	80.2 Å²	80.2	36%	0.364	41%	0.412	S	S	.	.			trans	-56.4	118.5	-174.5	19	-28.3	0	0	0	109.1	R327 N331 E332 L334	R327-P329 WeakPolarHBondContact O-CD 3.36Å; R327-P329 VanDerWaalsContact O-N 3.09Å; P329-N331 PolarHBondContact O-N 2.95Å; P329-E332 HydrophobicContact CB-CB 3.85Å; P329-E332 WeakPolarHBondContact CB-O 3.5Å; P329-E332 HydrophobicContact CG-CB 4.31Å; P329-E332 VanDerWaalsContact CG-O 3.27Å; P329-E332 WeakPolarHBondContact CG-O 3.33Å; P329-L334 HydrophobicContact CG-CD2 3.91Å; P329-L334 HydrophobicContact CG-CG 3.87Å
330	T	52	Low	64.3	Low	133 Å²	133	77 Å²	77	82%	0.816	39%	0.393	S	S	*	.	S	Bend	trans	-62.8	-29.6	178.9	-35.7	0	0	0	0	111	L328	L328-T330 PolarHBondContact O-N 3.01Å
331	N	40	Very low	62.9	Low	156 Å²	156	77.3 Å²	77.3	83%	0.834	40%	0.395	S	S	*	.	S	Bend	trans	-124.1	-19.1	-168.3	-67.3	-18.2	0	0	0	115.8	P329	P329-N331 PolarHBondContact O-N 2.95Å
332	E	49.4	Very low	62.1	Low	154 Å²	154	76.2 Å²	76.2	72%	0.72	39%	0.39	S	S	*	.	S	Bend	trans	-94.5	119.3	172.5	-67.6	-94.4	150.7	0	0	107.1	P329 L334	P329-E332 HydrophobicContact CB-CB 3.85Å; P329-E332 WeakPolarHBondContact CB-O 3.5Å; P329-E332 HydrophobicContact CG-CB 4.31Å; P329-E332 VanDerWaalsContact CG-O 3.27Å; P329-E332 WeakPolarHBondContact CG-O 3.33Å; E332-L334 PolarHBondContact O-N 3.18Å
333	T	47.9	Very low	61.5	Low	127 Å²	127	73.4 Å²	73.4	78%	0.779	37%	0.372	S	S	*	.			trans	-54.7	116.5	172.8	52.1	0	0	0	0	107.8
334	L	48.7	Very low	61	Low	47 Å²	47	73 Å²	73	25%	0.246	37%	0.369	C	S	.	.			trans	-44	128.3	176.4	-81.8	150.1	0	0	0	109	L328 P329 E332 K336 L338 F342	L328-L334 HydrophobicContact CB-CD1 4.45Å; L328-L334 HydrophobicContact CD2-CD1 3.51Å; L328-L334 HydrophobicContact CD2-CD2 3.82Å; L328-L334 HydrophobicContact CD2-CG 4.25Å; L328-L334 HydrophobicContact CG-CD1 4.46Å; P329-L334 HydrophobicContact CG-CD2 3.91Å; P329-L334 HydrophobicContact CG-CG 3.87Å; E332-L334 PolarHBondContact O-N 3.18Å; L334-K336 PolarHBondContact O-N 3.08Å; L334-L338 HydrophobicContact CB-CD1 4.32Å; L334-L338 HydrophobicContact CD2-CD1 3.61Å; L334-F342 HydrophobicContact CD1-CE2 4.43Å; L334-F342 HydrophobicContact CD1-CZ 3.89Å; L334-F342 HydrophobicContact CD2-CZ 4.31Å
335	P	49.8	Very low	61	Low	72 Å²	72	73 Å²	73	47%	0.468	37%	0.369	S	S	.	.			trans	-45.3	122.1	174.1	-27.3	28.8	0	0	0	108.8	E337 L338	P335-E337 PolarHBondContact O-N 3.14Å; P335-L338 HydrophobicContact CB-CD1 4.09Å; P335-L338 HydrophobicContact CG-CD1 3.98Å; P335-L338 WeakPolarHBondContact O-CB 3.47Å; P335-L338 PolarHBondContact O-N 3.48Å
336	K	49.2	Very low	61.7	Low	134 Å²	134	67.3 Å²	67.3	58%	0.583	35%	0.346	S	S	*	.	G	3₁₀ helix	trans	-63.6	-4.7	-168.9	-55	178	178.2	174.1	0	113.5	L334 H339 F391	L334-K336 PolarHBondContact O-N 3.08Å; K336-H339 VanDerWaalsContact C-CD2 3.41Å; K336-H339 VanDerWaalsContact CA-NE2 3.26Å; K336-H339 WeakPolarHBondContact CA-NE2 3.44Å; K336-H339 PolarHBondContact O-CD2 3.15Å; K336-H339 PolarHBondContact O-NE2 3.14Å; K336-F391 HydrophobicContact CB-CE1 3.6Å; K336-F391 HydrophobicContact CB-CZ 3.46Å; K336-F391 VanDerWaalsContact CB-CZ 3.46Å; K336-F391 WeakPolarHBondContact O-CE1 3.49Å; K336-F391 WeakPolarHBondContact O-CZ 3.4Å
337	E	48	Very low	62.3	Low	106 Å²	106	60.1 Å²	60.1	50%	0.495	31%	0.313	S	S	.	.	G	3₁₀ helix	trans	-84.9	-9.5	175.3	-54.8	177.1	169.4	0	0	113	P118 P335 H339 P340 F391	P118-E337 HydrophobicContact CB-CB 4.25Å; P118-E337 WeakPolarHBondContact CD-OE2 3.5Å; P118-E337 HydrophobicContact CG-CB 3.53Å; P335-E337 PolarHBondContact O-N 3.14Å; E337-H339 PolarHBondContact O-N 3.04Å; E337-P340 WeakPolarHBondContact O-CD 3.41Å; E337-F391 HydrophobicContact CG-CD1 4.09Å; E337-F391 HydrophobicContact CG-CE1 4.33Å
338	L	51.2	Low	63.4	Low	28 Å²	28	54.7 Å²	54.7	15%	0.147	29%	0.292	C	S	.	.	G	3₁₀ helix	trans	-71.5	-10.8	174.4	-81.9	147.7	0	0	0	113.2	P118 L334 P335 V341 F342	P118-L338 HydrophobicContact CB-CB 4.39Å; P118-L338 HydrophobicContact CB-CD2 3.94Å; P118-L338 HydrophobicContact CB-CG 3.69Å; L334-L338 HydrophobicContact CB-CD1 4.32Å; L334-L338 HydrophobicContact CD2-CD1 3.61Å; P335-L338 HydrophobicContact CB-CD1 4.09Å; P335-L338 HydrophobicContact CG-CD1 3.98Å; P335-L338 WeakPolarHBondContact O-CB 3.47Å; P335-L338 PolarHBondContact O-N 3.48Å; L338-V341 PolarHBondContact O-N 3.01Å; L338-V341 VanDerWaalsContact O-N 3.17Å; L338-F342 HydrophobicContact CB-CE2 3.86Å; L338-F342 VanDerWaalsContact O-CD2 3.3Å; L338-F342 WeakPolarHBondContact O-CD2 3.34Å
339	H	61.5	Low	65	Low	7 Å²	7	52.5 Å²	52.5	3%	0.032	28%	0.281	C	S	.	.	H	α-helix	trans	-57	-48	-169	-67.8	-38.2	0	0	0	114.8	K336 E337 V341 F342 L387 F388	K336-H339 VanDerWaalsContact C-CD2 3.41Å; K336-H339 VanDerWaalsContact CA-NE2 3.26Å; K336-H339 WeakPolarHBondContact CA-NE2 3.44Å; K336-H339 PolarHBondContact O-CD2 3.15Å; K336-H339 PolarHBondContact O-NE2 3.14Å; E337-H339 PolarHBondContact O-N 3.04Å; H339-V341 PolarHBondContact O-N 3.25Å; H339-V341 VanDerWaalsContact O-N 3.13Å; H339-F342 PolarHBondContact O-N 2.93Å; H339-F342 VanDerWaalsContact O-N 3.15Å; H339-L387 PolarHBondContact CD2-O 2.95Å; H339-L387 WeakPolarHBondContact CE1-CD2 3.47Å; H339-L387 WeakPolarHBondContact CE1-CG 3.35Å; H339-L387 WeakPolarHBondContact ND1-CD2 3.4Å; H339-L387 WeakPolarHBondContact NE2-CD1 3.34Å; H339-L387 WeakPolarHBondContact NE2-CG 3.35Å; H339-F388 HydrophobicContact CB-CD1 3.36Å; H339-F388 HydrophobicContact CB-CE1 3.41Å; H339-F388 VanDerWaalsContact CB-CE1 3.41Å; H339-F388 HydrophobicContact CB-CG 3.97Å; H339-F388 HydrophobicContact CB-CZ 4.03Å; H339-F388 WeakPolarHBondContact O-CE1 3.43Å
340	P	60.4	Low	66.9	Low	7 Å²	7	49.9 Å²	49.9	5%	0.045	26%	0.264	C	S	.	.	H	α-helix	trans	-53.4	-38.7	177	-13.9	16.3	0	0	0	114.7	E337 F342 F343 Y400	E337-P340 WeakPolarHBondContact O-CD 3.41Å; P340-F342 PolarHBondContact O-N 3.14Å; P340-F343 WeakPolarHBondContact O-CB 3.28Å; P340-F343 PolarHBondContact O-N 3.46Å; P340-F343 VanDerWaalsContact O-N 3.09Å; P340-Y400 WeakPolarHBondContact CA-OH 3.41Å; P340-Y400 HydrophobicContact CB-CD1 4.25Å; P340-Y400 HydrophobicContact CB-CD2 4.08Å; P340-Y400 HydrophobicContact CB-CE1 3.74Å; P340-Y400 HydrophobicContact CB-CE2 3.49Å; P340-Y400 VanDerWaalsContact CB-CE2 3.49Å; P340-Y400 HydrophobicContact CB-CG 4.4Å; P340-Y400 WeakPolarHBondContact CB-OH 3.4Å; P340-Y400 WeakPolarHBondContact CD-OH 3.26Å; P340-Y400 HydrophobicContact CG-CE1 4.35Å; P340-Y400 HydrophobicContact CG-CE2 3.71Å; P340-Y400 VanDerWaalsContact CG-CZ 3.48Å; P340-Y400 WeakPolarHBondContact CG-OH 3.36Å
341	V	62.3	Low	69.1	Low	6 Å²	6	43.6 Å²	43.6	4%	0.036	23%	0.225	C	C	.	.	H	α-helix	trans	-73.2	-21.1	-170.4	-150.3	0	0	0	0	111.1	P281 T282 L338 H339 F343 L344	P281-V341 HydrophobicContact CB-CB 4Å; P281-V341 HydrophobicContact CB-CG1 3.61Å; P281-V341 VanDerWaalsContact CB-O 3.27Å; P281-V341 WeakPolarHBondContact CB-O 3.42Å; P281-V341 HydrophobicContact CG-CB 4.31Å; P281-V341 HydrophobicContact CG-CG1 4.27Å; T282-V341 HydrophobicContact CG2-CG1 3.51Å; L338-V341 PolarHBondContact O-N 3.01Å; L338-V341 VanDerWaalsContact O-N 3.17Å; H339-V341 PolarHBondContact O-N 3.25Å; H339-V341 VanDerWaalsContact O-N 3.13Å; V341-F343 PolarHBondContact O-N 3.07Å; V341-L344 HydrophobicContact CG1-CD1 3.63Å; V341-L344 HydrophobicContact CG1-CG 4.27Å; V341-L344 VanDerWaalsContact O-CB 3.27Å; V341-L344 WeakPolarHBondContact O-CB 3.08Å; V341-L344 WeakPolarHBondContact O-CG 3.46Å; V341-L344 PolarHBondContact O-N 3.34Å
342	F	72.4	Confident	71.8	Confident	26 Å²	26	36.4 Å²	36.4	11%	0.114	19%	0.188	C	C	.	.	H	α-helix	trans	-65.4	-24.2	172.7	-71.6	-72.5	0	0	0	113.1	P281 L328 L334 L338 H339 P340 L344 F345 L381	P281-F342 HydrophobicContact CG-CE1 4.45Å; L328-F342 HydrophobicContact CD1-CE1 4.33Å; L328-F342 HydrophobicContact CD2-CE1 3.52Å; L328-F342 HydrophobicContact CD2-CZ 3.53Å; L334-F342 HydrophobicContact CD1-CE2 4.43Å; L334-F342 HydrophobicContact CD1-CZ 3.89Å; L334-F342 HydrophobicContact CD2-CZ 4.31Å; L338-F342 HydrophobicContact CB-CE2 3.86Å; L338-F342 VanDerWaalsContact O-CD2 3.3Å; L338-F342 WeakPolarHBondContact O-CD2 3.34Å; H339-F342 PolarHBondContact O-N 2.93Å; H339-F342 VanDerWaalsContact O-N 3.15Å; P340-F342 PolarHBondContact O-N 3.14Å; F342-L344 PolarHBondContact O-N 3.03Å; F342-F345 HydrophobicContact CD1-CD2 4.07Å; F342-F345 AromaticContact CD1-CE2 3.61Å; F342-F345 HydrophobicContact CD1-CE2 3.61Å; F342-F345 HydrophobicContact CD1-CZ 4.47Å; F342-F345 HydrophobicContact CE1-CE2 4.14Å; F342-F345 WeakPolarHBondContact O-CB 3.39Å; F342-F345 WeakPolarHBondContact O-CD2 3.28Å; F342-F345 PolarHBondContact O-N 2.81Å; F342-F345 VanDerWaalsContact O-N 3.13Å; F342-L381 HydrophobicContact CB-CD2 3.71Å
343	F	76.9	Confident	74.2	Confident	11 Å²	11	29.1 Å²	29.1	5%	0.048	15%	0.153	C	C	.	.	T	Hydrogen-bonded Turn	trans	-63.5	-22.7	172.3	-83.8	-98.5	0	0	0	112.2	P340 V341 F345 V346 L381 F388 Y400 P403 M404	P340-F343 WeakPolarHBondContact O-CB 3.28Å; P340-F343 PolarHBondContact O-N 3.46Å; P340-F343 VanDerWaalsContact O-N 3.09Å; V341-F343 PolarHBondContact O-N 3.07Å; F343-F345 PolarHBondContact O-N 3Å; F343-V346 VanDerWaalsContact O-CB 3.27Å; F343-V346 WeakPolarHBondContact O-CB 3.47Å; F343-V346 PolarHBondContact O-N 3.02Å; F343-L381 HydrophobicContact CD1-CD1 4.21Å; F343-L381 HydrophobicContact CD2-CD1 4.12Å; F343-L381 HydrophobicContact CE1-CB 4.36Å; F343-L381 HydrophobicContact CE1-CD1 4.46Å; F343-L381 HydrophobicContact CE2-CB 4.09Å; F343-L381 HydrophobicContact CE2-CD1 4.38Å; F343-L381 HydrophobicContact CG-CD1 4.04Å; F343-L381 HydrophobicContact CZ-CB 3.94Å; F343-F388 AromaticContact CD2-CE1 3.84Å; F343-F388 HydrophobicContact CD2-CE1 3.84Å; F343-F388 HydrophobicContact CD2-CZ 4.27Å; F343-F388 HydrophobicContact CE2-CD1 4.18Å; F343-F388 AromaticContact CE2-CE1 3.42Å; F343-F388 HydrophobicContact CE2-CE1 3.42Å; F343-F388 VanDerWaalsContact CE2-CE1 3.42Å; F343-F388 AromaticContact CE2-CZ 3.66Å; F343-F388 HydrophobicContact CE2-CZ 3.66Å; F343-Y400 HydrophobicContact CB-CD1 4.35Å; F343-Y400 AromaticContact CD2-CD1 3.46Å; F343-Y400 HydrophobicContact CD2-CD1 3.46Å; F343-Y400 VanDerWaalsContact CD2-CD1 3.46Å; F343-Y400 AromaticContact CD2-CE1 3.56Å; F343-Y400 HydrophobicContact CD2-CE1 3.56Å; F343-Y400 AromaticContact CE2-CD1 3.8Å; F343-Y400 HydrophobicContact CE2-CD1 3.8Å; F343-Y400 AromaticContact CE2-CE1 3.7Å; F343-Y400 HydrophobicContact CE2-CE1 3.7Å; F343-Y400 AromaticContact CG-CD1 3.87Å; F343-Y400 HydrophobicContact CG-CD1 3.87Å; F343-Y400 HydrophobicContact CG-CE1 4.41Å; F343-Y400 HydrophobicContact CZ-CD1 4.47Å; F343-P403 HydrophobicContact CB-CB 3.98Å; F343-P403 HydrophobicContact CB-CG 3.94Å; F343-P403 WeakPolarHBondContact O-CB 3.26Å; F343-P403 VanDerWaalsContact O-CG 3.27Å; F343-P403 WeakPolarHBondContact O-CG 3.47Å; F343-M404 HydrophobicContact CD1-SD 4.02Å; F343-M404 HydrophobicContact CE1-SD 3.58Å; F343-M404 VanDerWaalsContact CE1-SD 3.58Å
344	L	77.8	Confident	76.5	Confident	19 Å²	19	24.2 Å²	24.2	10%	0.099	12%	0.122	C	C	.	.	H	α-helix	trans	-63.6	-22.7	175.6	-59.9	-176.6	0	0	0	113.2	T282 H284 V341 F342 V346 A347 A399 P403	T282-L344 HydrophobicContact CG2-CD1 4.42Å; H284-L344 HydrophobicContact CB-CB 4.01Å; V341-L344 HydrophobicContact CG1-CD1 3.63Å; V341-L344 HydrophobicContact CG1-CG 4.27Å; V341-L344 VanDerWaalsContact O-CB 3.27Å; V341-L344 WeakPolarHBondContact O-CB 3.08Å; V341-L344 WeakPolarHBondContact O-CG 3.46Å; V341-L344 PolarHBondContact O-N 3.34Å; F342-L344 PolarHBondContact O-N 3.03Å; L344-V346 PolarHBondContact O-N 3.19Å; L344-A347 PolarHBondContact O-N 3.11Å; L344-A399 HydrophobicContact CD2-CB 4.33Å; L344-P403 HydrophobicContact CD2-CG 3.99Å
345	F	84.2	Confident	78.8	Confident	9 Å²	9	22 Å²	22	4%	0.039	11%	0.11	C	C	.	.	H	α-helix	trans	-63.8	-28.1	172.1	-77.1	-99.1	0	0	0	112.7	P281 H284 F321 L324 Y325 F342 F343 P349 L377	P281-F345 HydrophobicContact CB-CD2 4.27Å; P281-F345 HydrophobicContact CB-CE2 3.77Å; P281-F345 HydrophobicContact CG-CE2 3.92Å; H284-F345 AromaticContact CE1-CD1 3.42Å; H284-F345 VanDerWaalsContact CE1-CD1 3.42Å; H284-F345 WeakPolarHBondContact CE1-CD1 3.32Å; H284-F345 AromaticContact CE1-CD2 3.86Å; H284-F345 AromaticContact CE1-CE1 3.55Å; H284-F345 AromaticContact CE1-CE2 3.98Å; H284-F345 AromaticContact CE1-CG 3.62Å; H284-F345 AromaticContact CE1-CZ 3.86Å; H284-F345 AromaticContact NE2-CD1 3.59Å; H284-F345 AromaticContact NE2-CG 3.93Å; F321-F345 AromaticContact CD2-CD1 3.82Å; F321-F345 HydrophobicContact CD2-CD1 3.82Å; F321-F345 HydrophobicContact CD2-CE1 4.13Å; F321-F345 HydrophobicContact CE2-CD1 4.03Å; F321-F345 HydrophobicContact CE2-CE1 4.5Å; L324-F345 HydrophobicContact CB-CE1 4Å; L324-F345 HydrophobicContact CB-CZ 3.63Å; L324-F345 HydrophobicContact CD1-CE1 3.75Å; L324-F345 HydrophobicContact CD1-CE2 4.04Å; L324-F345 HydrophobicContact CD1-CZ 3.33Å; L324-F345 HydrophobicContact CG-CZ 4.07Å; Y325-F345 HydrophobicContact CD2-CE1 4.3Å; Y325-F345 HydrophobicContact CE2-CD1 4.47Å; Y325-F345 HydrophobicContact CE2-CE1 4.12Å; F342-F345 HydrophobicContact CD1-CD2 4.07Å; F342-F345 AromaticContact CD1-CE2 3.61Å; F342-F345 HydrophobicContact CD1-CE2 3.61Å; F342-F345 HydrophobicContact CD1-CZ 4.47Å; F342-F345 HydrophobicContact CE1-CE2 4.14Å; F342-F345 WeakPolarHBondContact O-CB 3.39Å; F342-F345 WeakPolarHBondContact O-CD2 3.28Å; F342-F345 PolarHBondContact O-N 2.81Å; F342-F345 VanDerWaalsContact O-N 3.13Å; F343-F345 PolarHBondContact O-N 3Å; F345-P349 WeakPolarHBondContact O-CD 3.07Å; F345-P349 WeakPolarHBondContact O-CG 3.45Å; F345-L377 HydrophobicContact CB-CD1 4.42Å
346	V	91.5	Very high	81.1	Confident	0 Å²	0	22.4 Å²	22.4	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-79.5	-37.2	-178.1	-173.2	0	0	0	0	110.8	F343 L344 A348 P349 A350 S374 L377 Y378 L381 P403 V407	F343-V346 VanDerWaalsContact O-CB 3.27Å; F343-V346 WeakPolarHBondContact O-CB 3.47Å; F343-V346 PolarHBondContact O-N 3.02Å; L344-V346 PolarHBondContact O-N 3.19Å; V346-A348 PolarHBondContact O-N 3.38Å; V346-P349 VanDerWaalsContact O-CD 3.29Å; V346-P349 WeakPolarHBondContact O-CD 3.23Å; V346-P349 WeakPolarHBondContact O-CG 3.36Å; V346-A350 PolarHBondContact O-N 2.85Å; V346-S374 WeakPolarHBondContact CG1-OG 3.48Å; V346-S374 PolarHBondContact O-OG 2.87Å; V346-L377 HydrophobicContact CG2-CB 3.95Å; V346-Y378 HydrophobicContact CG1-CD2 4.22Å; V346-L381 HydrophobicContact CG2-CD1 3.47Å; V346-L381 VanDerWaalsContact CG2-CD1 3.47Å; V346-P403 HydrophobicContact CB-CB 4.43Å; V346-V407 HydrophobicContact CB-CG2 4.48Å; V346-V407 HydrophobicContact CG1-CG2 3.13Å
347	A	93.2	Very high	83.4	Confident	0 Å²	0	17.2 Å²	17.2	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-62.5	-43.5	-175.6	0	0	0	0	0	113.4	V288 L344 A350 V351 F402 P403	V288-A347 HydrophobicContact CG2-CB 4.07Å; L344-A347 PolarHBondContact O-N 3.11Å; A347-A350 PolarHBondContact O-N 3.22Å; A347-V351 WeakPolarHBondContact O-CG2 3.42Å; A347-V351 PolarHBondContact O-N 3.45Å; A347-F402 HydrophobicContact CB-CD1 3.93Å; A347-F402 HydrophobicContact CB-CE1 3.35Å; A347-F402 HydrophobicContact CB-CZ 3.91Å; A347-P403 HydrophobicContact CB-CB 4.06Å; A347-P403 HydrophobicContact CB-CG 3.95Å
348	A	94.9	Very high	85.7	Confident	0 Å²	0	17.5 Å²	17.5	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-56.6	-55.8	-177.6	0	0	0	0	0	113	I287 V288 F291 Y317 V346 A350 V351 A352	I287-A348 HydrophobicContact CG2-CB 3.95Å; V288-A348 HydrophobicContact CG2-CB 4.2Å; F291-A348 HydrophobicContact CD2-CB 4.42Å; F291-A348 WeakPolarHBondContact CD2-O 3.46Å; F291-A348 HydrophobicContact CE2-CB 4.18Å; Y317-A348 HydrophobicContact CD2-CB 3.81Å; Y317-A348 HydrophobicContact CE2-CB 3.89Å; V346-A348 PolarHBondContact O-N 3.38Å; A348-A350 VanDerWaalsContact C-N 3.34Å; A348-A350 PolarHBondContact O-N 3.14Å; A348-V351 PolarHBondContact O-N 3.04Å; A348-A352 WeakPolarHBondContact O-CB 3.36Å; A348-A352 PolarHBondContact O-N 2.85Å
349	P	96.7	Very high	87.9	Confident	5 Å²	5	18.4 Å²	18.4	3%	0.032	9%	0.086	C	C	.	.	H	α-helix	trans	-65.3	-32.4	177.4	25.2	-33.8	0	0	0	113.2	F345 V346 A352 S353 A370 I373 L377	F345-P349 WeakPolarHBondContact O-CD 3.07Å; F345-P349 WeakPolarHBondContact O-CG 3.45Å; V346-P349 VanDerWaalsContact O-CD 3.29Å; V346-P349 WeakPolarHBondContact O-CD 3.23Å; V346-P349 WeakPolarHBondContact O-CG 3.36Å; P349-A352 PolarHBondContact O-N 3.41Å; P349-S353 PolarHBondContact O-N 3.25Å; P349-A370 WeakPolarHBondContact CB-O 3.34Å; P349-A370 WeakPolarHBondContact O-CB 3.09Å; P349-I373 HydrophobicContact CB-CB 4.34Å; P349-I373 HydrophobicContact CB-CG2 4.01Å; P349-I373 HydrophobicContact CG-CG2 4.19Å; P349-L377 HydrophobicContact CG-CD1 4.22Å
350	A	97.3	Very high	89.5	Confident	0 Å²	0	19.9 Å²	19.9	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-62.3	-48.8	173.9	0	0	0	0	0	112.4	V346 A347 A348 S353 M354 S374 A406 V407 A410	V346-A350 PolarHBondContact O-N 2.85Å; A347-A350 PolarHBondContact O-N 3.22Å; A348-A350 VanDerWaalsContact C-N 3.34Å; A348-A350 PolarHBondContact O-N 3.14Å; A350-S353 WeakPolarHBondContact O-CB 3.43Å; A350-S353 PolarHBondContact O-N 3.27Å; A350-M354 PolarHBondContact O-N 2.67Å; A350-S374 WeakPolarHBondContact CB-OG 3.38Å; A350-A406 HydrophobicContact CB-CB 3.74Å; A350-V407 HydrophobicContact CB-CG2 4.37Å; A350-A410 HydrophobicContact CB-CB 4.47Å
351	V	97.3	Very high	91	Very high	1 Å²	1	24.1 Å²	24.1	1%	0.006	13%	0.133	C	C	.	.	H	α-helix	trans	-69.7	-35.4	178.2	-176.3	0	0	0	0	111.2	F291 A292 L295 A347 A348 S353 M354 A355 F402 A406	F291-V351 HydrophobicContact CB-CB 4.11Å; F291-V351 HydrophobicContact CB-CG1 3.67Å; A292-V351 HydrophobicContact CB-CG1 4.46Å; L295-V351 HydrophobicContact CD2-CG1 4.49Å; A347-V351 WeakPolarHBondContact O-CG2 3.42Å; A347-V351 PolarHBondContact O-N 3.45Å; A348-V351 PolarHBondContact O-N 3.04Å; V351-S353 VanDerWaalsContact C-N 3.33Å; V351-S353 PolarHBondContact O-N 3.26Å; V351-M354 HydrophobicContact CB-CE 4.34Å; V351-M354 HydrophobicContact CG1-CE 4.47Å; V351-M354 HydrophobicContact CG2-CE 4.02Å; V351-M354 PolarHBondContact O-N 3.16Å; V351-A355 WeakPolarHBondContact O-CB 3.19Å; V351-A355 PolarHBondContact O-N 3.27Å; V351-F402 HydrophobicContact CG2-CE2 4.13Å; V351-F402 HydrophobicContact CG2-CZ 3.71Å; V351-A406 HydrophobicContact CG2-CB 4.09Å
352	A	98	Very high	92.5	Very high	6 Å²	6	26.8 Å²	26.8	5%	0.05	15%	0.152	C	C	.	.	H	α-helix	trans	-59.1	-43.7	173.1	0	0	0	0	0	111.6	F291 F310 A348 P349 M354 A355 W356 A370	F291-A352 HydrophobicContact CD1-CB 3.96Å; F291-A352 HydrophobicContact CD2-CB 3.87Å; F291-A352 HydrophobicContact CE1-CB 3.96Å; F291-A352 HydrophobicContact CE2-CB 3.85Å; F291-A352 HydrophobicContact CG-CB 3.93Å; F291-A352 HydrophobicContact CZ-CB 3.9Å; F310-A352 HydrophobicContact CE2-CB 4.13Å; F310-A352 WeakPolarHBondContact CE2-O 3.26Å; F310-A352 HydrophobicContact CZ-CB 4.44Å; A348-A352 WeakPolarHBondContact O-CB 3.36Å; A348-A352 PolarHBondContact O-N 2.85Å; P349-A352 PolarHBondContact O-N 3.41Å; A352-M354 VanDerWaalsContact C-N 3.34Å; A352-M354 PolarHBondContact O-N 3.3Å; A352-A355 PolarHBondContact O-N 3.1Å; A352-W356 WeakPolarHBondContact O-CB 3.27Å; A352-W356 PolarHBondContact O-N 3.17Å; A352-A370 HydrophobicContact CB-CB 4.33Å
353	S	98.1	Very high	93.5	Very high	0 Å²	0	26 Å²	26	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-57.3	-46	175.3	-179.6	0	0	0	0	112.2	P349 A350 V351 T357 F363 S367	P349-S353 PolarHBondContact O-N 3.25Å; A350-S353 WeakPolarHBondContact O-CB 3.43Å; A350-S353 PolarHBondContact O-N 3.27Å; V351-S353 VanDerWaalsContact C-N 3.33Å; V351-S353 PolarHBondContact O-N 3.26Å; S353-T357 WeakPolarHBondContact O-CB 3.35Å; S353-T357 PolarHBondContact O-N 3.13Å; S353-T357 PolarHBondContact O-OG1 3.46Å; S353-F363 WeakPolarHBondContact OG-CZ 3.14Å; S353-S367 WeakPolarHBondContact CB-O 3.1Å; S353-S367 PolarHBondContact O-OG 3.42Å; S353-S367 PolarHBondContact OG-O 2.87Å
354	M	97.1	Very high	94.3	Very high	25 Å²	25	27.8 Å²	27.8	12%	0.123	16%	0.158	C	C	.	.	H	α-helix	trans	-66.2	-43	177.3	-64.3	-170.4	-66.2	0	0	112.2	L295 A350 V351 A352 T357 K358 A410	L295-M354 HydrophobicContact CD1-CB 4.19Å; L295-M354 WeakPolarHBondContact CD1-O 3.29Å; L295-M354 HydrophobicContact CD2-CB 4.03Å; L295-M354 HydrophobicContact CD2-CE 4.27Å; A350-M354 PolarHBondContact O-N 2.67Å; V351-M354 HydrophobicContact CB-CE 4.34Å; V351-M354 HydrophobicContact CG1-CE 4.47Å; V351-M354 HydrophobicContact CG2-CE 4.02Å; V351-M354 PolarHBondContact O-N 3.16Å; A352-M354 VanDerWaalsContact C-N 3.34Å; A352-M354 PolarHBondContact O-N 3.3Å; M354-T357 WeakPolarHBondContact O-CB 3.48Å; M354-T357 PolarHBondContact O-N 2.75Å; M354-K358 PolarHBondContact O-N 2.75Å; M354-A410 HydrophobicContact CG-CB 4.39Å
355	A	97.9	Very high	95.2	Very high	0 Å²	0	32.9 Å²	32.9	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-62.1	-47.3	179.3	0	0	0	0	0	111.2	F291 A294 L295 F310 V351 A352 T357 K358 I359	F291-A355 WeakPolarHBondContact O-CB 3.13Å; A294-A355 HydrophobicContact CB-CB 4.28Å; L295-A355 HydrophobicContact CB-CB 3.88Å; F310-A355 HydrophobicContact CD2-CB 4.01Å; F310-A355 HydrophobicContact CE2-CB 4.17Å; V351-A355 WeakPolarHBondContact O-CB 3.19Å; V351-A355 PolarHBondContact O-N 3.27Å; A352-A355 PolarHBondContact O-N 3.1Å; A355-T357 VanDerWaalsContact C-N 3.34Å; A355-T357 PolarHBondContact O-N 3.24Å; A355-K358 PolarHBondContact O-N 3.36Å; A355-K358 VanDerWaalsContact O-N 3.11Å; A355-I359 WeakPolarHBondContact O-CG1 3.43Å; A355-I359 PolarHBondContact O-N 3.04Å
356	W	98	Very high	95.7	Very high	81 Å²	81	33.7 Å²	33.7	31%	0.307	20%	0.196	S	C	.	.	H	α-helix	trans	-61.3	-42.3	177.5	-168.9	-95.5	0	0	0	111.8	F310 A352 K358 I359 S360 D364	F310-W356 AromaticContact CD1-CE3 3.79Å; F310-W356 HydrophobicContact CD1-CE3 3.79Å; F310-W356 AromaticContact CD1-CZ3 3.86Å; F310-W356 HydrophobicContact CD1-CZ3 3.86Å; F310-W356 HydrophobicContact CD2-CE3 4.42Å; F310-W356 HydrophobicContact CE1-CD2 4.35Å; F310-W356 AromaticContact CE1-CE3 3.28Å; F310-W356 HydrophobicContact CE1-CE3 3.28Å; F310-W356 AromaticContact CE1-CZ3 3.56Å; F310-W356 HydrophobicContact CE1-CZ3 3.56Å; F310-W356 HydrophobicContact CE2-CB 3.99Å; F310-W356 AromaticContact CE2-CE3 3.98Å; F310-W356 HydrophobicContact CE2-CE3 3.98Å; F310-W356 HydrophobicContact CG-CE3 4.34Å; F310-W356 HydrophobicContact CZ-CB 4.06Å; F310-W356 HydrophobicContact CZ-CD2 4.13Å; F310-W356 AromaticContact CZ-CE3 3.4Å; F310-W356 HydrophobicContact CZ-CE3 3.4Å; F310-W356 HydrophobicContact CZ-CG 4.43Å; F310-W356 HydrophobicContact CZ-CZ3 4.16Å; A352-W356 WeakPolarHBondContact O-CB 3.27Å; A352-W356 PolarHBondContact O-N 3.17Å; W356-K358 PolarHBondContact O-N 2.95Å; W356-I359 PolarHBondContact O-N 3.3Å; W356-S360 PolarHBondContact NE1-OG 3.47Å; W356-S360 VanDerWaalsContact NE1-OG 3.09Å; W356-S360 PolarHBondContact O-N 3.04Å; W356-D364 PolarHBondContact NE1-OD1 2.81Å; W356-D364 PolarHBondContact NE1-OD2 2.85Å
357	T	97	Very high	96	Very high	25 Å²	25	33.7 Å²	33.7	15%	0.153	20%	0.196	C	C	.	.	H	α-helix	trans	-55.7	-37.8	174.8	-56.9	0	0	0	0	112.2	S353 M354 A355 A361 S362 F363 S367	S353-T357 WeakPolarHBondContact O-CB 3.35Å; S353-T357 PolarHBondContact O-N 3.13Å; S353-T357 PolarHBondContact O-OG1 3.46Å; M354-T357 WeakPolarHBondContact O-CB 3.48Å; M354-T357 PolarHBondContact O-N 2.75Å; A355-T357 VanDerWaalsContact C-N 3.34Å; A355-T357 PolarHBondContact O-N 3.24Å; T357-A361 CarbonylContact O-C 3.59Å; T357-A361 WeakPolarHBondContact O-CA 3.39Å; T357-A361 PolarHBondContact O-N 3.35Å; T357-A361 VanDerWaalsContact O-N 3.07Å; T357-S362 PolarHBondContact O-N 2.7Å; T357-F363 HydrophobicContact CG2-CB 4.31Å; T357-F363 HydrophobicContact CG2-CD2 3.98Å; T357-F363 WeakPolarHBondContact OG1-CD2 3.44Å; T357-S367 WeakPolarHBondContact CA-OG 3.44Å; T357-S367 PolarHBondContact N-OG 3.31Å; T357-S367 VanDerWaalsContact N-OG 3.14Å; T357-S367 WeakPolarHBondContact OG1-CB 3.43Å; T357-S367 PolarHBondContact OG1-OG 2.95Å
358	K	96.1	Very high	96.2	Very high	112 Å²	112	37.6 Å²	37.6	49%	0.487	21%	0.211	S	C	.	.	H	α-helix	trans	-76	-31.3	176.2	-70.6	-56.7	-171	178.8	0	113.4	L295 A298 M354 A355 W356	L295-K358 HydrophobicContact CD1-CB 4.17Å; L295-K358 HydrophobicContact CD1-CG 3.52Å; A298-K358 HydrophobicContact CB-CB 3.7Å; M354-K358 PolarHBondContact O-N 2.75Å; A355-K358 PolarHBondContact O-N 3.36Å; A355-K358 VanDerWaalsContact O-N 3.11Å; W356-K358 PolarHBondContact O-N 2.95Å
359	I	96.7	Very high	96.3	Very high	46 Å²	46	42.4 Å²	42.4	24%	0.236	24%	0.235	C	C	.	.	H	α-helix	trans	-71.1	-48.2	175.5	-67.1	167.1	0	0	0	110.7	A298 P306 I307 F310 A355 W356 A361	A298-I359 HydrophobicContact CB-CG1 3.84Å; P306-I359 HydrophobicContact CB-CD1 4.44Å; P306-I359 HydrophobicContact CB-CG1 4.35Å; I307-I359 HydrophobicContact CD1-CG2 4.4Å; I307-I359 HydrophobicContact CG1-CG2 3.91Å; F310-I359 HydrophobicContact CB-CD1 3.96Å; F310-I359 HydrophobicContact CD2-CD1 4.02Å; F310-I359 HydrophobicContact CG-CD1 4.05Å; A355-I359 WeakPolarHBondContact O-CG1 3.43Å; A355-I359 PolarHBondContact O-N 3.04Å; W356-I359 PolarHBondContact O-N 3.3Å; I359-A361 VanDerWaalsContact C-N 3.3Å; I359-A361 PolarHBondContact O-N 2.88Å
360	S	95.1	Very high	96.3	Very high	39 Å²	39	42.9 Å²	42.9	27%	0.273	24%	0.24	S	C	.	.	S	Bend	trans	-80.2	-6.5	-179.7	-66.1	0	0	0	0	114.4	W356 S362 D364	W356-S360 PolarHBondContact NE1-OG 3.47Å; W356-S360 VanDerWaalsContact NE1-OG 3.09Å; W356-S360 PolarHBondContact O-N 3.04Å; S360-S362 PolarHBondContact O-N 3.29Å; S360-S362 PolarHBondContact O-OG 3Å; S360-D364 WeakPolarHBondContact CB-OD2 3.38Å; S360-D364 PolarHBondContact OG-OD2 2.81Å
361	A	92.9	Very high	96.3	Very high	95 Å²	95	42.9 Å²	42.9	79%	0.785	24%	0.24	S	C	*	.	S	Bend	trans	56.1	12.7	-172.8	0	0	0	0	0	115.5	T357 I359	T357-A361 CarbonylContact O-C 3.59Å; T357-A361 WeakPolarHBondContact O-CA 3.39Å; T357-A361 PolarHBondContact O-N 3.35Å; T357-A361 VanDerWaalsContact O-N 3.07Å; I359-A361 VanDerWaalsContact C-N 3.3Å; I359-A361 PolarHBondContact O-N 2.88Å
362	S	93.5	Very high	96.4	Very high	62 Å²	62	47.6 Å²	47.6	43%	0.434	26%	0.26	S	S	.	.	S	Bend	trans	-152.9	154.7	-178.8	58.5	0	0	0	0	110.8	T357 S360 D364	T357-S362 PolarHBondContact O-N 2.7Å; S360-S362 PolarHBondContact O-N 3.29Å; S360-S362 PolarHBondContact O-OG 3Å; S362-D364 PolarHBondContact O-N 2.86Å
363	F	93.2	Very high	96.2	Very high	11 Å²	11	51 Å²	51	5%	0.048	28%	0.277	C	S	.	.			trans	-84.1	65.4	177.4	-158.4	-84.6	0	0	0	110.5	S353 T357 R368 Y371 K413 Y414 E417	S353-F363 WeakPolarHBondContact OG-CZ 3.14Å; T357-F363 HydrophobicContact CG2-CB 4.31Å; T357-F363 HydrophobicContact CG2-CD2 3.98Å; T357-F363 WeakPolarHBondContact OG1-CD2 3.44Å; F363-R368 HydrophobicContact CD1-CG 3.77Å; F363-R368 HydrophobicContact CE1-CB 4.44Å; F363-R368 HydrophobicContact CE1-CG 3.64Å; F363-R368 PolarHBondContact O-NE 3.39Å; F363-R368 VanDerWaalsContact O-NE 3.15Å; F363-Y371 HydrophobicContact CZ-CG 4.35Å; F363-K413 HydrophobicContact CD2-CB 4.23Å; F363-K413 HydrophobicContact CE2-CB 4.12Å; F363-Y414 HydrophobicContact CD1-CD2 4.33Å; F363-Y414 AromaticContact CE1-CD2 3.69Å; F363-Y414 HydrophobicContact CE1-CD2 3.69Å; F363-Y414 HydrophobicContact CZ-CD2 4.34Å; F363-E417 HydrophobicContact CB-CB 4.09Å; F363-E417 HydrophobicContact CB-CG 4.02Å; F363-E417 HydrophobicContact CD1-CB 4.39Å; F363-E417 HydrophobicContact CD1-CG 4.33Å; F363-E417 HydrophobicContact CG-CB 4.4Å
364	D	94.2	Very high	96.2	Very high	47 Å²	47	51 Å²	51	25%	0.251	28%	0.277	S	S	.	.			trans	-75.3	-170.4	-172.9	71.9	13.2	0	0	0	113.7	W356 S360 S362 G366 S367 R368	W356-D364 PolarHBondContact NE1-OD1 2.81Å; W356-D364 PolarHBondContact NE1-OD2 2.85Å; S360-D364 WeakPolarHBondContact CB-OD2 3.38Å; S360-D364 PolarHBondContact OG-OD2 2.81Å; S362-D364 PolarHBondContact O-N 2.86Å; D364-G366 VanDerWaalsContact C-N 3.3Å; D364-G366 PolarHBondContact O-N 3.15Å; D364-G366 WeakPolarHBondContact OD1-CA 3.46Å; D364-G366 PolarHBondContact OD1-N 3.31Å; D364-S367 PolarHBondContact O-N 3.4Å; D364-S367 PolarHBondContact OD1-N 2.93Å; D364-S367 VanDerWaalsContact OD1-N 3.13Å; D364-R368 VanDerWaalsContact O-CG 3.25Å; D364-R368 WeakPolarHBondContact O-CG 3.42Å; D364-R368 PolarHBondContact O-N 3.17Å
365	L	95.4	Very high	96.1	Very high	127 Å²	127	50.8 Å²	50.8	67%	0.665	28%	0.276	S	S	*	.	H	α-helix	trans	-56.7	-39.7	177.5	-178.8	63.4	0	0	0	112.9	R368 L369	L365-R368 PolarHBondContact O-N 3.4Å; L365-L369 HydrophobicContact CD1-CD1 4.44Å; L365-L369 HydrophobicContact CD1-CG 4.22Å; L365-L369 HydrophobicContact CG-CD1 4.13Å; L365-L369 HydrophobicContact CG-CG 4.35Å; L365-L369 VanDerWaalsContact O-CG 3.3Å; L365-L369 WeakPolarHBondContact O-CG 3.24Å; L365-L369 PolarHBondContact O-N 3.34Å
366	G	95.5	Very high	96	Very high	25 Å²	25	57.7 Å²	57.7	26%	0.258	31%	0.307	S	S	.	.	H	α-helix	trans	-64.4	-44.1	-179.7	0	0	0	0	0	111.4	D364 R368 L369 A370	D364-G366 VanDerWaalsContact C-N 3.3Å; D364-G366 PolarHBondContact O-N 3.15Å; D364-G366 WeakPolarHBondContact OD1-CA 3.46Å; D364-G366 PolarHBondContact OD1-N 3.31Å; G366-R368 PolarHBondContact O-N 3.01Å; G366-L369 PolarHBondContact O-N 2.88Å; G366-A370 PolarHBondContact O-N 3.43Å
367	S	97	Very high	95.7	Very high	0 Å²	0	54.5 Å²	54.5	0%	0	30%	0.296	C	S	.	.	H	α-helix	trans	-62.7	-41.9	174.4	-63.1	0	0	0	0	112.1	S353 T357 D364 Y371	S353-S367 WeakPolarHBondContact CB-O 3.1Å; S353-S367 PolarHBondContact O-OG 3.42Å; S353-S367 PolarHBondContact OG-O 2.87Å; T357-S367 WeakPolarHBondContact CA-OG 3.44Å; T357-S367 PolarHBondContact N-OG 3.31Å; T357-S367 VanDerWaalsContact N-OG 3.14Å; T357-S367 WeakPolarHBondContact OG1-CB 3.43Å; T357-S367 PolarHBondContact OG1-OG 2.95Å; D364-S367 PolarHBondContact O-N 3.4Å; D364-S367 PolarHBondContact OD1-N 2.93Å; D364-S367 VanDerWaalsContact OD1-N 3.13Å; S367-Y371 VanDerWaalsContact O-CB 3.24Å; S367-Y371 WeakPolarHBondContact O-CB 3.42Å; S367-Y371 PolarHBondContact O-N 3.45Å
368	R	97.4	Very high	95.5	Very high	83 Å²	83	53.7 Å²	53.7	31%	0.313	29%	0.29	S	S	.	.	H	α-helix	trans	-65.4	-43.3	178.9	-69.6	170.3	-168.3	-154.9	1.4	112.1	F363 D364 L365 G366 Y371 F372 E417	F363-R368 HydrophobicContact CD1-CG 3.77Å; F363-R368 HydrophobicContact CE1-CB 4.44Å; F363-R368 HydrophobicContact CE1-CG 3.64Å; F363-R368 PolarHBondContact O-NE 3.39Å; F363-R368 VanDerWaalsContact O-NE 3.15Å; D364-R368 VanDerWaalsContact O-CG 3.25Å; D364-R368 WeakPolarHBondContact O-CG 3.42Å; D364-R368 PolarHBondContact O-N 3.17Å; L365-R368 PolarHBondContact O-N 3.4Å; G366-R368 PolarHBondContact O-N 3.01Å; R368-Y371 PolarHBondContact O-N 2.91Å; R368-F372 HydrophobicContact CB-CD2 4.35Å; R368-F372 HydrophobicContact CB-CE2 4.26Å; R368-F372 WeakPolarHBondContact O-CD2 3.31Å; R368-F372 PolarHBondContact O-N 3.39Å; R368-E417 IonicContact NH2-OE1 3.74Å; R368-E417 PolarHBondContact NH2-OE1 3.05Å
369	L	97.4	Very high	95.4	Very high	100 Å²	100	52.4 Å²	52.4	52%	0.524	28%	0.284	S	S	.	.	H	α-helix	trans	-59.7	-51.8	177.4	-74.5	172	0	0	0	111.2	L365 G366 Y371 F372 I373	L365-L369 HydrophobicContact CD1-CD1 4.44Å; L365-L369 HydrophobicContact CD1-CG 4.22Å; L365-L369 HydrophobicContact CG-CD1 4.13Å; L365-L369 HydrophobicContact CG-CG 4.35Å; L365-L369 VanDerWaalsContact O-CG 3.3Å; L365-L369 WeakPolarHBondContact O-CG 3.24Å; L365-L369 PolarHBondContact O-N 3.34Å; G366-L369 PolarHBondContact O-N 2.88Å; L369-Y371 VanDerWaalsContact C-N 3.31Å; L369-Y371 PolarHBondContact O-N 2.93Å; L369-F372 PolarHBondContact O-N 3.29Å; L369-I373 VanDerWaalsContact O-CG1 3.26Å; L369-I373 WeakPolarHBondContact O-CG1 3.25Å; L369-I373 PolarHBondContact O-N 3.18Å
370	A	97.4	Very high	95	Very high	15 Å²	15	52.4 Å²	52.4	12%	0.124	29%	0.289	C	S	.	.	H	α-helix	trans	-60.9	-41.1	177.7	0	0	0	0	0	111.6	P349 A352 G366 S374	P349-A370 WeakPolarHBondContact CB-O 3.34Å; P349-A370 WeakPolarHBondContact O-CB 3.09Å; A352-A370 HydrophobicContact CB-CB 4.33Å; G366-A370 PolarHBondContact O-N 3.43Å; A370-S374 WeakPolarHBondContact O-CB 3.47Å; A370-S374 PolarHBondContact O-N 2.85Å
371	Y	97.7	Very high	94.5	Very high	1 Å²	1	51.8 Å²	51.8	0%	0.004	28%	0.282	C	S	.	.	H	α-helix	trans	-61.5	-49.2	175.7	169.4	-110.6	0	0	0	112.7	F363 S367 R368 L369 I373 S374 L375 A410 T411 Y414	F363-Y371 HydrophobicContact CZ-CG 4.35Å; S367-Y371 VanDerWaalsContact O-CB 3.24Å; S367-Y371 WeakPolarHBondContact O-CB 3.42Å; S367-Y371 PolarHBondContact O-N 3.45Å; R368-Y371 PolarHBondContact O-N 2.91Å; L369-Y371 VanDerWaalsContact C-N 3.31Å; L369-Y371 PolarHBondContact O-N 2.93Å; Y371-I373 PolarHBondContact O-N 2.91Å; Y371-S374 CarbonylContact O-C 3.59Å; Y371-S374 WeakPolarHBondContact O-CB 3.26Å; Y371-S374 PolarHBondContact O-N 2.98Å; Y371-S374 VanDerWaalsContact O-N 3.15Å; Y371-L375 HydrophobicContact CE1-CD2 4.21Å; Y371-L375 WeakPolarHBondContact O-CB 3.45Å; Y371-L375 PolarHBondContact O-N 2.88Å; Y371-A410 HydrophobicContact CD2-CB 3.87Å; Y371-A410 HydrophobicContact CE2-CB 4.41Å; Y371-T411 WeakPolarHBondContact CE2-OG1 3.35Å; Y371-Y414 HydrophobicContact CD1-CD1 4.4Å; Y371-Y414 AromaticContact CD1-CD2 3.79Å; Y371-Y414 HydrophobicContact CD1-CD2 3.79Å; Y371-Y414 HydrophobicContact CD1-CE2 4.29Å; Y371-Y414 AromaticContact CD1-CG 3.84Å; Y371-Y414 HydrophobicContact CD1-CG 3.84Å; Y371-Y414 AromaticContact CE1-CD1 3.5Å; Y371-Y414 HydrophobicContact CE1-CD1 3.5Å; Y371-Y414 AromaticContact CE1-CD2 3.72Å; Y371-Y414 HydrophobicContact CE1-CD2 3.72Å; Y371-Y414 AromaticContact CE1-CE1 3.98Å; Y371-Y414 HydrophobicContact CE1-CE1 3.98Å; Y371-Y414 HydrophobicContact CE1-CE2 4.16Å; Y371-Y414 AromaticContact CE1-CG 3.35Å; Y371-Y414 HydrophobicContact CE1-CG 3.35Å; Y371-Y414 AromaticContact CZ-CD1 3.84Å; Y371-Y414 AromaticContact CZ-CG 3.81Å
372	F	97.7	Very high	94.2	Very high	99 Å²	99	49.7 Å²	49.7	43%	0.434	26%	0.259	S	S	.	.	H	α-helix	trans	-67.4	-34.8	-179.2	-75.3	-58.6	0	0	0	112.8	R368 L369 S374 L375 F376 Y414	R368-F372 HydrophobicContact CB-CD2 4.35Å; R368-F372 HydrophobicContact CB-CE2 4.26Å; R368-F372 WeakPolarHBondContact O-CD2 3.31Å; R368-F372 PolarHBondContact O-N 3.39Å; L369-F372 PolarHBondContact O-N 3.29Å; F372-S374 VanDerWaalsContact C-N 3.34Å; F372-L375 HydrophobicContact CD1-CD2 4.32Å; F372-L375 PolarHBondContact O-N 3.02Å; F372-F376 WeakPolarHBondContact O-CB 3.23Å; F372-F376 PolarHBondContact O-N 2.97Å; F372-Y414 HydrophobicContact CE2-CE2 4.41Å; F372-Y414 AromaticContact CZ-CE2 3.99Å; F372-Y414 HydrophobicContact CZ-CE2 3.99Å; F372-Y414 AromaticContact CZ-CZ 3.82Å
373	I	95.8	Very high	93.8	Very high	77 Å²	77	51.9 Å²	51.9	40%	0.395	27%	0.273	S	S	.	.	H	α-helix	trans	-59.1	-49.1	170.2	-68.9	165.5	0	0	0	109.6	P349 L369 Y371 L375 F376 L377	P349-I373 HydrophobicContact CB-CB 4.34Å; P349-I373 HydrophobicContact CB-CG2 4.01Å; P349-I373 HydrophobicContact CG-CG2 4.19Å; L369-I373 VanDerWaalsContact O-CG1 3.26Å; L369-I373 WeakPolarHBondContact O-CG1 3.25Å; L369-I373 PolarHBondContact O-N 3.18Å; Y371-I373 PolarHBondContact O-N 2.91Å; I373-L375 VanDerWaalsContact C-N 3.34Å; I373-L375 PolarHBondContact O-N 3.22Å; I373-F376 PolarHBondContact O-N 3.35Å; I373-L377 HydrophobicContact CG2-CD1 3.97Å; I373-L377 VanDerWaalsContact O-CG 3.31Å; I373-L377 WeakPolarHBondContact O-CG 3.32Å; I373-L377 PolarHBondContact O-N 3.29Å
374	S	96.5	Very high	93.2	Very high	0 Å²	0	59 Å²	59	0%	0	30%	0.3	C	S	.	.	H	α-helix	trans	-59.1	-44.9	177.2	-172.1	0	0	0	0	112.1	V346 A350 A370 Y371 F372 L377 Y378 V407	V346-S374 WeakPolarHBondContact CG1-OG 3.48Å; V346-S374 PolarHBondContact O-OG 2.87Å; A350-S374 WeakPolarHBondContact CB-OG 3.38Å; A370-S374 WeakPolarHBondContact O-CB 3.47Å; A370-S374 PolarHBondContact O-N 2.85Å; Y371-S374 CarbonylContact O-C 3.59Å; Y371-S374 WeakPolarHBondContact O-CB 3.26Å; Y371-S374 PolarHBondContact O-N 2.98Å; Y371-S374 VanDerWaalsContact O-N 3.15Å; F372-S374 VanDerWaalsContact C-N 3.34Å; S374-L377 PolarHBondContact O-N 3.15Å; S374-Y378 VanDerWaalsContact O-CB 3.26Å; S374-Y378 WeakPolarHBondContact O-CB 3.44Å; S374-Y378 PolarHBondContact O-N 3.43Å; S374-V407 WeakPolarHBondContact OG-CG2 3.26Å
375	L	95.9	Very high	92.2	Very high	21 Å²	21	61.1 Å²	61.1	11%	0.11	31%	0.31	C	S	.	.	H	α-helix	trans	-65.4	-41.9	-178	-169.8	66	0	0	0	111.5	Y371 F372 I373 Y378 F379 L426	Y371-L375 HydrophobicContact CE1-CD2 4.21Å; Y371-L375 WeakPolarHBondContact O-CB 3.45Å; Y371-L375 PolarHBondContact O-N 2.88Å; F372-L375 HydrophobicContact CD1-CD2 4.32Å; F372-L375 PolarHBondContact O-N 3.02Å; I373-L375 VanDerWaalsContact C-N 3.34Å; I373-L375 PolarHBondContact O-N 3.22Å; L375-Y378 WeakPolarHBondContact O-CB 3.25Å; L375-Y378 PolarHBondContact O-N 2.91Å; L375-F379 HydrophobicContact CD1-CD2 4Å; L375-F379 HydrophobicContact CD1-CE2 3.44Å; L375-F379 VanDerWaalsContact CD1-CE2 3.44Å; L375-F379 HydrophobicContact CD1-CZ 4.15Å; L375-F379 HydrophobicContact CD2-CE2 4.12Å; L375-F379 HydrophobicContact CG-CD2 3.83Å; L375-F379 HydrophobicContact CG-CE2 3.56Å; L375-F379 VanDerWaalsContact O-CD2 3.23Å; L375-F379 WeakPolarHBondContact O-CD2 3.37Å; L375-F379 PolarHBondContact O-N 3.26Å; L375-L426 HydrophobicContact CD1-CD2 4.41Å; L375-L426 HydrophobicContact CD2-CD2 4.41Å
376	F	95.5	Very high	90.9	Very high	146 Å²	146	60.3 Å²	60.3	64%	0.64	31%	0.307	S	S	*	.	H	α-helix	trans	-62.9	-47.8	175.5	178.1	-97.9	0	0	0	111.8	F372 I373 Y378 F379 S380	F372-F376 WeakPolarHBondContact O-CB 3.23Å; F372-F376 PolarHBondContact O-N 2.97Å; I373-F376 PolarHBondContact O-N 3.35Å; F376-Y378 VanDerWaalsContact C-N 3.3Å; F376-Y378 PolarHBondContact O-N 3.45Å; F376-F379 PolarHBondContact O-N 2.94Å; F376-S380 VanDerWaalsContact O-CB 3.29Å; F376-S380 WeakPolarHBondContact O-CB 3.46Å; F376-S380 PolarHBondContact O-N 3.48Å
377	L	92.4	Very high	89.5	Confident	14 Å²	14	62.4 Å²	62.4	7%	0.073	31%	0.312	C	S	.	.	H	α-helix	trans	-61.4	-41.7	177.1	-69	172.4	0	0	0	111.3	F321 F345 V346 P349 I373 S374 S380 L381	F321-L377 HydrophobicContact CE2-CD1 4.22Å; F321-L377 HydrophobicContact CE2-CD2 4.28Å; F345-L377 HydrophobicContact CB-CD1 4.42Å; V346-L377 HydrophobicContact CG2-CB 3.95Å; P349-L377 HydrophobicContact CG-CD1 4.22Å; I373-L377 HydrophobicContact CG2-CD1 3.97Å; I373-L377 VanDerWaalsContact O-CG 3.31Å; I373-L377 WeakPolarHBondContact O-CG 3.32Å; I373-L377 PolarHBondContact O-N 3.29Å; S374-L377 PolarHBondContact O-N 3.15Å; L377-S380 PolarHBondContact O-N 2.89Å; L377-L381 WeakPolarHBondContact O-CG 3.37Å; L377-L381 PolarHBondContact O-N 3.28Å; L377-L381 VanDerWaalsContact O-N 3.09Å
378	Y	93.2	Very high	87.8	Confident	8 Å²	8	63.6 Å²	63.6	3%	0.031	32%	0.317	C	S	.	.	H	α-helix	trans	-58.3	-54.8	176	-178.6	-89.9	0	0	0	111.7	V346 S374 L375 F376 S380 L381 V382 M404 V407 M430	V346-Y378 HydrophobicContact CG1-CD2 4.22Å; S374-Y378 VanDerWaalsContact O-CB 3.26Å; S374-Y378 WeakPolarHBondContact O-CB 3.44Å; S374-Y378 PolarHBondContact O-N 3.43Å; L375-Y378 WeakPolarHBondContact O-CB 3.25Å; L375-Y378 PolarHBondContact O-N 2.91Å; F376-Y378 VanDerWaalsContact C-N 3.3Å; F376-Y378 PolarHBondContact O-N 3.45Å; Y378-S380 VanDerWaalsContact C-N 3.32Å; Y378-S380 PolarHBondContact O-N 3.31Å; Y378-L381 PolarHBondContact O-N 3.45Å; Y378-V382 HydrophobicContact CD1-CG2 3.99Å; Y378-V382 HydrophobicContact CE1-CG2 3.6Å; Y378-V382 WeakPolarHBondContact O-CG2 3.49Å; Y378-V382 PolarHBondContact O-N 3.39Å; Y378-M404 HydrophobicContact CD2-SD 4.34Å; Y378-M404 HydrophobicContact CE2-CE 3.85Å; Y378-M404 HydrophobicContact CE2-SD 3.36Å; Y378-M404 WeakPolarHBondContact CE2-SD 3.32Å; Y378-M404 WeakPolarHBondContact OH-CE 3.17Å; Y378-V407 HydrophobicContact CD2-CB 4.2Å; Y378-V407 HydrophobicContact CD2-CG1 4.13Å; Y378-V407 HydrophobicContact CD2-CG2 3.82Å; Y378-V407 HydrophobicContact CE2-CB 4.5Å; Y378-V407 HydrophobicContact CE2-CG1 4.47Å; Y378-V407 HydrophobicContact CG-CG1 4.22Å; Y378-V407 HydrophobicContact CG-CG2 4.34Å; Y378-M430 HydrophobicContact CD1-SD 3.93Å; Y378-M430 HydrophobicContact CE1-CE 3.74Å; Y378-M430 HydrophobicContact CE1-SD 3.23Å; Y378-M430 WeakPolarHBondContact CE1-SD 3.18Å; Y378-M430 HydrophobicContact CE2-SD 4.36Å
379	F	92.7	Very high	86.2	Confident	84 Å²	84	68.1 Å²	68.1	37%	0.368	33%	0.334	S	S	.	.	H	α-helix	trans	-64.5	-36.9	-179.8	-76.4	-56.8	0	0	0	112.6	L375 F376 L381 V382 C383 L426 M430	L375-F379 HydrophobicContact CD1-CD2 4Å; L375-F379 HydrophobicContact CD1-CE2 3.44Å; L375-F379 VanDerWaalsContact CD1-CE2 3.44Å; L375-F379 HydrophobicContact CD1-CZ 4.15Å; L375-F379 HydrophobicContact CD2-CE2 4.12Å; L375-F379 HydrophobicContact CG-CD2 3.83Å; L375-F379 HydrophobicContact CG-CE2 3.56Å; L375-F379 VanDerWaalsContact O-CD2 3.23Å; L375-F379 WeakPolarHBondContact O-CD2 3.37Å; L375-F379 PolarHBondContact O-N 3.26Å; F376-F379 PolarHBondContact O-N 2.94Å; F379-L381 VanDerWaalsContact C-N 3.27Å; F379-L381 PolarHBondContact O-N 2.89Å; F379-V382 PolarHBondContact O-N 3.38Å; F379-C383 WeakPolarHBondContact O-CB 3.31Å; F379-C383 PolarHBondContact O-N 3.27Å; F379-C383 PolarHBondContact O-SG 3.34Å; F379-L426 HydrophobicContact CZ-CD1 3.89Å; F379-M430 HydrophobicContact CE1-CE 4.49Å
380	S	88.2	Confident	84.6	Confident	47 Å²	47	67.3 Å²	67.3	33%	0.329	35%	0.35	S	S	.	.	H	α-helix	trans	-58	-40.3	174.6	-174.8	0	0	0	0	112.1	F376 L377 Y378 R384	F376-S380 VanDerWaalsContact O-CB 3.29Å; F376-S380 WeakPolarHBondContact O-CB 3.46Å; F376-S380 PolarHBondContact O-N 3.48Å; L377-S380 PolarHBondContact O-N 2.89Å; Y378-S380 VanDerWaalsContact C-N 3.32Å; Y378-S380 PolarHBondContact O-N 3.31Å; S380-R384 WeakPolarHBondContact O-CG 3.35Å; S380-R384 PolarHBondContact O-N 2.92Å
381	L	85.8	Confident	83.1	Confident	26 Å²	26	69.1 Å²	69.1	14%	0.136	36%	0.355	C	S	.	.	H	α-helix	trans	-72.3	-41.9	175.6	-67.5	169.2	0	0	0	112.3	F342 F343 V346 L377 Y378 F379 R384 I385 F388	F342-L381 HydrophobicContact CB-CD2 3.71Å; F343-L381 HydrophobicContact CD1-CD1 4.21Å; F343-L381 HydrophobicContact CD2-CD1 4.12Å; F343-L381 HydrophobicContact CE1-CB 4.36Å; F343-L381 HydrophobicContact CE1-CD1 4.46Å; F343-L381 HydrophobicContact CE2-CB 4.09Å; F343-L381 HydrophobicContact CE2-CD1 4.38Å; F343-L381 HydrophobicContact CG-CD1 4.04Å; F343-L381 HydrophobicContact CZ-CB 3.94Å; V346-L381 HydrophobicContact CG2-CD1 3.47Å; V346-L381 VanDerWaalsContact CG2-CD1 3.47Å; L377-L381 WeakPolarHBondContact O-CG 3.37Å; L377-L381 PolarHBondContact O-N 3.28Å; L377-L381 VanDerWaalsContact O-N 3.09Å; Y378-L381 PolarHBondContact O-N 3.45Å; F379-L381 VanDerWaalsContact C-N 3.27Å; F379-L381 PolarHBondContact O-N 2.89Å; L381-R384 CarbonylContact O-C 3.5Å; L381-R384 WeakPolarHBondContact O-CA 3.43Å; L381-R384 PolarHBondContact O-N 3.31Å; L381-I385 PolarHBondContact O-N 3.42Å; L381-F388 HydrophobicContact CD2-CZ 4.23Å
382	V	86	Confident	82	Confident	51 Å²	51	78.2 Å²	78.2	31%	0.309	40%	0.395	S	S	.	.	H	α-helix	trans	-63	-42.2	177.8	172.3	0	0	0	0	111.6	Y378 F379 R384 I385	Y378-V382 HydrophobicContact CD1-CG2 3.99Å; Y378-V382 HydrophobicContact CE1-CG2 3.6Å; Y378-V382 WeakPolarHBondContact O-CG2 3.49Å; Y378-V382 PolarHBondContact O-N 3.39Å; F379-V382 PolarHBondContact O-N 3.38Å; V382-R384 PolarHBondContact O-N 3.42Å; V382-R384 VanDerWaalsContact O-N 3.15Å; V382-I385 VanDerWaalsContact O-CB 3.25Å; V382-I385 WeakPolarHBondContact O-CB 3.27Å; V382-I385 WeakPolarHBondContact O-CG2 3.26Å; V382-I385 PolarHBondContact O-N 2.86Å
383	C	84.9	Confident	81.1	Confident	108 Å²	108	74.8 Å²	74.8	73%	0.73	38%	0.379	S	S	*	.	H	α-helix	trans	-60.8	-24.6	174.7	-71.2	0	0	0	0	112.4	F379	F379-C383 WeakPolarHBondContact O-CB 3.31Å; F379-C383 PolarHBondContact O-N 3.27Å; F379-C383 PolarHBondContact O-SG 3.34Å
384	R	80.9	Confident	80.3	Confident	160 Å²	160	73.4 Å²	73.4	60%	0.604	38%	0.376	S	S	*	.	T	Hydrogen-bonded Turn	trans	-95.3	18.4	175.9	-65	-176.9	-177.6	-134.9	0.1	112.8	S380 L381 V382 N386 L387 F388	S380-R384 WeakPolarHBondContact O-CG 3.35Å; S380-R384 PolarHBondContact O-N 2.92Å; L381-R384 CarbonylContact O-C 3.5Å; L381-R384 WeakPolarHBondContact O-CA 3.43Å; L381-R384 PolarHBondContact O-N 3.31Å; V382-R384 PolarHBondContact O-N 3.42Å; V382-R384 VanDerWaalsContact O-N 3.15Å; R384-N386 PolarHBondContact O-N 3.45Å; R384-L387 HydrophobicContact CB-CD2 4.48Å; R384-L387 WeakPolarHBondContact O-CB 3.37Å; R384-L387 PolarHBondContact O-N 2.64Å; R384-F388 HydrophobicContact CB-CE2 4.45Å; R384-F388 VanDerWaalsContact O-CD2 3.26Å; R384-F388 WeakPolarHBondContact O-CD2 3.12Å; R384-F388 WeakPolarHBondContact O-CE2 3.2Å
385	I	73.7	Confident	79.6	Confident	91 Å²	91	74.3 Å²	74.3	47%	0.467	38%	0.381	S	S	.	.	G	3₁₀ helix	trans	-56.9	-26.5	-175	-163.2	141.4	0	0	0	115	L381 V382 L387 F388	L381-I385 PolarHBondContact O-N 3.42Å; V382-I385 VanDerWaalsContact O-CB 3.25Å; V382-I385 WeakPolarHBondContact O-CB 3.27Å; V382-I385 WeakPolarHBondContact O-CG2 3.26Å; V382-I385 PolarHBondContact O-N 2.86Å; I385-L387 PolarHBondContact O-N 3.29Å; I385-F388 WeakPolarHBondContact O-CB 3.5Å; I385-F388 PolarHBondContact O-N 3.01Å
386	N	67.8	Low	78.9	Confident	111 Å²	111	73.9 Å²	73.9	59%	0.594	38%	0.381	S	S	*	.	G	3₁₀ helix	trans	-59.9	-27.1	174.3	-76.5	-23	0	0	0	112.9	R384 F388 R389	R384-N386 PolarHBondContact O-N 3.45Å; N386-F388 PolarHBondContact O-N 3.37Å; N386-R389 PolarHBondContact O-N 2.94Å; N386-R389 PolarHBondContact OD1-NH1 3.17Å
387	L	64.7	Low	78.4	Confident	69 Å²	69	69.7 Å²	69.7	36%	0.361	36%	0.361	S	S	.	.	G	3₁₀ helix	trans	-65	-22.2	175.6	-169.1	58	0	0	0	111.8	H339 R384 I385 F391	H339-L387 PolarHBondContact CD2-O 2.95Å; H339-L387 WeakPolarHBondContact CE1-CD2 3.47Å; H339-L387 WeakPolarHBondContact CE1-CG 3.35Å; H339-L387 WeakPolarHBondContact ND1-CD2 3.4Å; H339-L387 WeakPolarHBondContact NE2-CD1 3.34Å; H339-L387 WeakPolarHBondContact NE2-CG 3.35Å; R384-L387 HydrophobicContact CB-CD2 4.48Å; R384-L387 WeakPolarHBondContact O-CB 3.37Å; R384-L387 PolarHBondContact O-N 2.64Å; I385-L387 PolarHBondContact O-N 3.29Å; L387-F391 WeakPolarHBondContact O-CE2 3.43Å
388	F	62.3	Low	78.2	Confident	24 Å²	24	69.2 Å²	69.2	11%	0.105	36%	0.358	C	S	.	.	G	3₁₀ helix	trans	-98.4	4.6	-174	-57.3	-107.4	0	0	0	113.5	H339 F343 L381 R384 I385 N386 F391 Y400	H339-F388 HydrophobicContact CB-CD1 3.36Å; H339-F388 HydrophobicContact CB-CE1 3.41Å; H339-F388 VanDerWaalsContact CB-CE1 3.41Å; H339-F388 HydrophobicContact CB-CG 3.97Å; H339-F388 HydrophobicContact CB-CZ 4.03Å; H339-F388 WeakPolarHBondContact O-CE1 3.43Å; F343-F388 AromaticContact CD2-CE1 3.84Å; F343-F388 HydrophobicContact CD2-CE1 3.84Å; F343-F388 HydrophobicContact CD2-CZ 4.27Å; F343-F388 HydrophobicContact CE2-CD1 4.18Å; F343-F388 AromaticContact CE2-CE1 3.42Å; F343-F388 HydrophobicContact CE2-CE1 3.42Å; F343-F388 VanDerWaalsContact CE2-CE1 3.42Å; F343-F388 AromaticContact CE2-CZ 3.66Å; F343-F388 HydrophobicContact CE2-CZ 3.66Å; L381-F388 HydrophobicContact CD2-CZ 4.23Å; R384-F388 HydrophobicContact CB-CE2 4.45Å; R384-F388 VanDerWaalsContact O-CD2 3.26Å; R384-F388 WeakPolarHBondContact O-CD2 3.12Å; R384-F388 WeakPolarHBondContact O-CE2 3.2Å; I385-F388 WeakPolarHBondContact O-CB 3.5Å; I385-F388 PolarHBondContact O-N 3.01Å; N386-F388 PolarHBondContact O-N 3.37Å; F388-F391 VanDerWaalsContact C-CE2 3.44Å; F388-F391 WeakPolarHBondContact O-CD2 3.31Å; F388-Y400 AromaticContact CD1-CE1 3.75Å; F388-Y400 HydrophobicContact CD1-CE1 3.75Å; F388-Y400 AromaticContact CD1-CZ 3.96Å; F388-Y400 VanDerWaalsContact CD1-OH 3.31Å; F388-Y400 WeakPolarHBondContact CD1-OH 3.35Å; F388-Y400 AromaticContact CE1-CE1 3.92Å; F388-Y400 HydrophobicContact CE1-CE1 3.92Å
389	R	64	Low	77.8	Confident	179 Å²	179	69.7 Å²	69.7	68%	0.675	36%	0.364	S	S	*	.			trans	-90.3	142.5	-179.1	-71.3	179.5	169.8	165.8	-7.9	112.2	N386 F391	N386-R389 PolarHBondContact O-N 2.94Å; N386-R389 PolarHBondContact OD1-NH1 3.17Å; R389-F391 WeakPolarHBondContact O-CE2 3.2Å
390	G	62.6	Low	77.5	Confident	83 Å²	83	66.8 Å²	66.8	86%	0.856	35%	0.351	S	S	*	.	S	Bend	trans	99.7	10.7	167.5	0	0	0	0	0	116.8
391	F	67.3	Low	77.7	Confident	53 Å²	53	64.6 Å²	64.6	23%	0.232	34%	0.335	C	S	.	.	P	Polyproline II helix	trans	-94	150.7	-178.6	-52.9	-70.3	0	0	0	112.9	K336 E337 L387 F388 R389 W397	K336-F391 HydrophobicContact CB-CE1 3.6Å; K336-F391 HydrophobicContact CB-CZ 3.46Å; K336-F391 VanDerWaalsContact CB-CZ 3.46Å; K336-F391 WeakPolarHBondContact O-CE1 3.49Å; K336-F391 WeakPolarHBondContact O-CZ 3.4Å; E337-F391 HydrophobicContact CG-CD1 4.09Å; E337-F391 HydrophobicContact CG-CE1 4.33Å; L387-F391 WeakPolarHBondContact O-CE2 3.43Å; F388-F391 VanDerWaalsContact C-CE2 3.44Å; F388-F391 WeakPolarHBondContact O-CD2 3.31Å; R389-F391 WeakPolarHBondContact O-CE2 3.2Å; F391-W397 HydrophobicContact CB-CZ2 4.2Å
392	K	73.1	Confident	78.1	Confident	192 Å²	192	63.9 Å²	63.9	84%	0.835	33%	0.331	S	S	*	.	P	Polyproline II helix	trans	-68.9	142.2	167.1	-67.4	-177.4	179.3	177.3	0	109	S394 W397	K392-S394 PolarHBondContact O-N 2.83Å; K392-W397 PolarHBondContact O-NE1 3.45Å
393	F	79.3	Confident	78.4	Confident	27 Å²	27	61.4 Å²	61.4	12%	0.118	32%	0.316	C	S	.	.	P	Polyproline II helix	trans	-60.2	137.5	174.3	173.8	-97.9	0	0	0	110	W397 V441 L444 T445 H448 L455	F393-W397 HydrophobicContact CD2-CB 4.38Å; F393-W397 HydrophobicContact CD2-CD2 4.11Å; F393-W397 HydrophobicContact CD2-CE3 4.25Å; F393-W397 HydrophobicContact CD2-CG 4.18Å; F393-W397 HydrophobicContact CE2-CB 4.17Å; F393-W397 HydrophobicContact CE2-CG 4.46Å; F393-V441 HydrophobicContact CE2-CG1 4.34Å; F393-L444 HydrophobicContact CD2-CB 3.52Å; F393-L444 HydrophobicContact CD2-CD1 3.81Å; F393-L444 HydrophobicContact CD2-CG 4.28Å; F393-L444 HydrophobicContact CE2-CB 3.62Å; F393-L444 HydrophobicContact CE2-CD1 4.42Å; F393-L444 HydrophobicContact CG-CB 4.02Å; F393-L444 HydrophobicContact CZ-CB 4.21Å; F393-T445 WeakPolarHBondContact CZ-OG1 3.35Å; F393-H448 HydrophobicContact CD1-CB 4.04Å; F393-H448 AromaticContact CD1-CD2 3.28Å; F393-H448 WeakPolarHBondContact CD1-CD2 3.37Å; F393-H448 AromaticContact CD1-CG 3.58Å; F393-H448 AromaticContact CD1-NE2 3.83Å; F393-H448 HydrophobicContact CE1-CB 4.1Å; F393-H448 AromaticContact CG-CD2 3.77Å; F393-L455 HydrophobicContact CE1-CD1 3.86Å
394	S	80.1	Confident	78.8	Confident	47 Å²	47	57 Å²	57	33%	0.329	29%	0.285	S	S	.	.			trans	-141.7	163.6	170.5	72	0	0	0	0	109.5	K392 A396 W397	K392-S394 PolarHBondContact O-N 2.83Å; S394-A396 PolarHBondContact O-N 2.88Å; S394-A396 VanDerWaalsContact O-N 3.1Å; S394-A396 WeakPolarHBondContact OG-CB 3.2Å; S394-W397 WeakPolarHBondContact O-CB 3.39Å; S394-W397 PolarHBondContact O-N 3.34Å
395	L	82	Confident	79.5	Confident	20 Å²	20	49.4 Å²	49.4	11%	0.105	26%	0.256	C	S	.	.	G	3₁₀ helix	trans	-59.4	-24.5	178.5	-162.5	63.6	0	0	0	112.5	P144 S147 M150 W397 W398 L455 F456	P144-L395 HydrophobicContact CG-CD2 4.05Å; S147-L395 WeakPolarHBondContact OG-CD2 3.45Å; M150-L395 HydrophobicContact CE-CD1 4.19Å; M150-L395 HydrophobicContact CG-CD1 4Å; M150-L395 HydrophobicContact SD-CD1 3.87Å; L395-W397 PolarHBondContact O-N 3.44Å; L395-W397 VanDerWaalsContact O-N 3.14Å; L395-W398 WeakPolarHBondContact O-CB 3.18Å; L395-W398 PolarHBondContact O-N 2.86Å; L395-W398 VanDerWaalsContact O-N 3.14Å; L395-L455 HydrophobicContact CD1-CD1 4.34Å; L395-F456 HydrophobicContact CD2-CE1 4.07Å
396	A	79.9	Confident	80.6	Confident	12 Å²	12	45.2 Å²	45.2	10%	0.099	24%	0.235	C	C	.	.	G	3₁₀ helix	trans	-56.6	-24.6	174.1	0	0	0	0	0	114	E119 S394 W398 A399	E119-A396 VanDerWaalsContact CD-CB 3.48Å; E119-A396 WeakPolarHBondContact OE1-CB 3.27Å; S394-A396 PolarHBondContact O-N 2.88Å; S394-A396 VanDerWaalsContact O-N 3.1Å; S394-A396 WeakPolarHBondContact OG-CB 3.2Å; A396-W398 PolarHBondContact O-N 2.91Å; A396-W398 VanDerWaalsContact O-N 3.15Å; A396-A399 WeakPolarHBondContact O-CB 3.38Å; A396-A399 PolarHBondContact O-N 3.42Å
397	W	84.5	Confident	82	Confident	57 Å²	57	40 Å²	40	22%	0.216	21%	0.207	C	C	.	.	G	3₁₀ helix	trans	-63.2	-20.5	178.9	-75.1	46.3	0	0	0	112.4	F391 K392 F393 S394 L395 A399 Y400 V441 L444	F391-W397 HydrophobicContact CB-CZ2 4.2Å; K392-W397 PolarHBondContact O-NE1 3.45Å; F393-W397 HydrophobicContact CD2-CB 4.38Å; F393-W397 HydrophobicContact CD2-CD2 4.11Å; F393-W397 HydrophobicContact CD2-CE3 4.25Å; F393-W397 HydrophobicContact CD2-CG 4.18Å; F393-W397 HydrophobicContact CE2-CB 4.17Å; F393-W397 HydrophobicContact CE2-CG 4.46Å; S394-W397 WeakPolarHBondContact O-CB 3.39Å; S394-W397 PolarHBondContact O-N 3.34Å; L395-W397 PolarHBondContact O-N 3.44Å; L395-W397 VanDerWaalsContact O-N 3.14Å; W397-A399 PolarHBondContact O-N 3.36Å; W397-A399 VanDerWaalsContact O-N 3.17Å; W397-Y400 HydrophobicContact CB-CD2 4.18Å; W397-Y400 HydrophobicContact CB-CE2 4.29Å; W397-Y400 HydrophobicContact CD2-CE2 4.17Å; W397-Y400 HydrophobicContact CE3-CE2 4.42Å; W397-Y400 HydrophobicContact CG-CD2 4.48Å; W397-Y400 HydrophobicContact CG-CE2 4.12Å; W397-Y400 WeakPolarHBondContact O-CB 3.16Å; W397-Y400 WeakPolarHBondContact O-CD2 3.45Å; W397-Y400 PolarHBondContact O-N 2.66Å; W397-Y400 VanDerWaalsContact O-N 3.1Å; W397-V441 HydrophobicContact CB-CG1 4.31Å; W397-V441 HydrophobicContact CB-CG2 4.31Å; W397-L444 HydrophobicContact CE3-CD1 4.26Å; W397-L444 HydrophobicContact CZ3-CD1 3.99Å
398	W	89.4	Confident	83.5	Confident	4 Å²	4	36.7 Å²	36.7	2%	0.015	19%	0.19	C	C	.	.	H	α-helix	trans	-60.4	-22.1	169.8	-77.6	94.2	0	0	0	112.9	M150 V154 L395 A396 Y400 T401 V438 V441 L442 T445	M150-W398 HydrophobicContact CB-CD2 4.1Å; M150-W398 HydrophobicContact CB-CE3 4.43Å; M150-W398 HydrophobicContact CB-CG 4.46Å; M150-W398 HydrophobicContact CB-CZ2 4.34Å; M150-W398 HydrophobicContact CG-CD2 3.83Å; M150-W398 HydrophobicContact CG-CG 3.85Å; M150-W398 HydrophobicContact CG-CZ2 4.15Å; V154-W398 HydrophobicContact CG2-CH2 3.75Å; V154-W398 HydrophobicContact CG2-CZ3 3.72Å; L395-W398 WeakPolarHBondContact O-CB 3.18Å; L395-W398 PolarHBondContact O-N 2.86Å; L395-W398 VanDerWaalsContact O-N 3.14Å; A396-W398 PolarHBondContact O-N 2.91Å; A396-W398 VanDerWaalsContact O-N 3.15Å; W398-Y400 PolarHBondContact O-N 3.11Å; W398-T401 HydrophobicContact CE3-CG2 3.8Å; W398-T401 HydrophobicContact CZ3-CG2 4.19Å; W398-T401 PolarHBondContact O-N 2.91Å; W398-T401 VanDerWaalsContact O-N 3.08Å; W398-T401 PolarHBondContact O-OG1 3.38Å; W398-V438 HydrophobicContact CZ3-CG1 4.42Å; W398-V441 HydrophobicContact CD2-CG1 3.65Å; W398-V441 HydrophobicContact CE3-CG1 4.24Å; W398-V441 HydrophobicContact CG-CG1 3.83Å; W398-V441 HydrophobicContact CZ2-CG1 4.14Å; W398-L442 HydrophobicContact CH2-CB 4.12Å; W398-L442 HydrophobicContact CH2-CD1 4.04Å; W398-L442 HydrophobicContact CZ2-CB 4.24Å; W398-L442 HydrophobicContact CZ2-CD1 3.96Å; W398-T445 PolarHBondContact NE1-OG1 3.45Å
399	A	84.7	Confident	85.1	Confident	19 Å²	19	35.7 Å²	35.7	16%	0.157	19%	0.186	C	C	.	.	H	α-helix	trans	-63.1	-18.5	174.2	0	0	0	0	0	114.2	L344 A396 W397 P403	L344-A399 HydrophobicContact CD2-CB 4.33Å; A396-A399 WeakPolarHBondContact O-CB 3.38Å; A396-A399 PolarHBondContact O-N 3.42Å; W397-A399 PolarHBondContact O-N 3.36Å; W397-A399 VanDerWaalsContact O-N 3.17Å; A399-P403 WeakPolarHBondContact O-CD 3.25Å; A399-P403 VanDerWaalsContact O-CG 3.23Å; A399-P403 WeakPolarHBondContact O-CG 3.34Å
400	Y	85.5	Confident	86.7	Confident	23 Å²	23	27.1 Å²	27.1	9%	0.09	15%	0.154	C	C	.	.	H	α-helix	trans	-71.6	-38.7	171.7	-67.3	-67.4	0	0	0	112.4	P340 F343 F388 W397 W398 P403 M404	P340-Y400 WeakPolarHBondContact CA-OH 3.41Å; P340-Y400 HydrophobicContact CB-CD1 4.25Å; P340-Y400 HydrophobicContact CB-CD2 4.08Å; P340-Y400 HydrophobicContact CB-CE1 3.74Å; P340-Y400 HydrophobicContact CB-CE2 3.49Å; P340-Y400 VanDerWaalsContact CB-CE2 3.49Å; P340-Y400 HydrophobicContact CB-CG 4.4Å; P340-Y400 WeakPolarHBondContact CB-OH 3.4Å; P340-Y400 WeakPolarHBondContact CD-OH 3.26Å; P340-Y400 HydrophobicContact CG-CE1 4.35Å; P340-Y400 HydrophobicContact CG-CE2 3.71Å; P340-Y400 VanDerWaalsContact CG-CZ 3.48Å; P340-Y400 WeakPolarHBondContact CG-OH 3.36Å; F343-Y400 HydrophobicContact CB-CD1 4.35Å; F343-Y400 AromaticContact CD2-CD1 3.46Å; F343-Y400 HydrophobicContact CD2-CD1 3.46Å; F343-Y400 VanDerWaalsContact CD2-CD1 3.46Å; F343-Y400 AromaticContact CD2-CE1 3.56Å; F343-Y400 HydrophobicContact CD2-CE1 3.56Å; F343-Y400 AromaticContact CE2-CD1 3.8Å; F343-Y400 HydrophobicContact CE2-CD1 3.8Å; F343-Y400 AromaticContact CE2-CE1 3.7Å; F343-Y400 HydrophobicContact CE2-CE1 3.7Å; F343-Y400 AromaticContact CG-CD1 3.87Å; F343-Y400 HydrophobicContact CG-CD1 3.87Å; F343-Y400 HydrophobicContact CG-CE1 4.41Å; F343-Y400 HydrophobicContact CZ-CD1 4.47Å; F388-Y400 AromaticContact CD1-CE1 3.75Å; F388-Y400 HydrophobicContact CD1-CE1 3.75Å; F388-Y400 AromaticContact CD1-CZ 3.96Å; F388-Y400 VanDerWaalsContact CD1-OH 3.31Å; F388-Y400 WeakPolarHBondContact CD1-OH 3.35Å; F388-Y400 AromaticContact CE1-CE1 3.92Å; F388-Y400 HydrophobicContact CE1-CE1 3.92Å; W397-Y400 HydrophobicContact CB-CD2 4.18Å; W397-Y400 HydrophobicContact CB-CE2 4.29Å; W397-Y400 HydrophobicContact CD2-CE2 4.17Å; W397-Y400 HydrophobicContact CE3-CE2 4.42Å; W397-Y400 HydrophobicContact CG-CD2 4.48Å; W397-Y400 HydrophobicContact CG-CE2 4.12Å; W397-Y400 WeakPolarHBondContact O-CB 3.16Å; W397-Y400 WeakPolarHBondContact O-CD2 3.45Å; W397-Y400 PolarHBondContact O-N 2.66Å; W397-Y400 VanDerWaalsContact O-N 3.1Å; W398-Y400 PolarHBondContact O-N 3.11Å; Y400-P403 WeakPolarHBondContact O-CD 3.42Å; Y400-M404 WeakPolarHBondContact O-CG 3.46Å; Y400-M404 PolarHBondContact O-N 3.02Å
401	T	92.9	Very high	88.3	Confident	0 Å²	0	23.2 Å²	23.2	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-64.2	-52.3	-162.5	58.7	0	0	0	0	112.6	G153 W398 M404 T405 T437 V438 V441	G153-T401 WeakPolarHBondContact CA-OG1 3.49Å; W398-T401 HydrophobicContact CE3-CG2 3.8Å; W398-T401 HydrophobicContact CZ3-CG2 4.19Å; W398-T401 PolarHBondContact O-N 2.91Å; W398-T401 VanDerWaalsContact O-N 3.08Å; W398-T401 PolarHBondContact O-OG1 3.38Å; T401-M404 PolarHBondContact O-N 2.98Å; T401-T405 PolarHBondContact O-N 3.48Å; T401-T405 VanDerWaalsContact O-N 3.09Å; T401-T405 PolarHBondContact O-OG1 3.33Å; T401-T437 HydrophobicContact CG2-CG2 4.34Å; T401-V438 HydrophobicContact CG2-CB 4.43Å; T401-V438 HydrophobicContact CG2-CG2 3.57Å; T401-V441 HydrophobicContact CG2-CB 4.16Å; T401-V441 HydrophobicContact CG2-CG1 4.32Å; T401-V441 HydrophobicContact CG2-CG2 4.17Å
402	F	93.5	Very high	89.7	Confident	11 Å²	11	20.7 Å²	20.7	5%	0.048	10%	0.102	C	C	.	.	H	α-helix	trans	-60.4	-50.6	-178.1	162.6	-116	0	0	0	112.7	F231 V288 A347 V351 M404 T405 A406	F231-F402 HydrophobicContact CE1-CE2 4.32Å; F231-F402 AromaticContact CE2-CD2 3.48Å; F231-F402 HydrophobicContact CE2-CD2 3.48Å; F231-F402 VanDerWaalsContact CE2-CD2 3.48Å; F231-F402 AromaticContact CE2-CE2 3.33Å; F231-F402 HydrophobicContact CE2-CE2 3.33Å; F231-F402 HydrophobicContact CE2-CG 4.23Å; F231-F402 AromaticContact CE2-CZ 3.96Å; F231-F402 HydrophobicContact CE2-CZ 3.96Å; F231-F402 AromaticContact CZ-CD2 3.87Å; F231-F402 HydrophobicContact CZ-CD2 3.87Å; F231-F402 HydrophobicContact CZ-CE1 4.41Å; F231-F402 AromaticContact CZ-CE2 3.19Å; F231-F402 HydrophobicContact CZ-CE2 3.19Å; F231-F402 AromaticContact CZ-CZ 3.52Å; F231-F402 HydrophobicContact CZ-CZ 3.52Å; V288-F402 HydrophobicContact CB-CE1 4.33Å; V288-F402 HydrophobicContact CG1-CE1 3.52Å; V288-F402 HydrophobicContact CG1-CZ 3.45Å; V288-F402 VanDerWaalsContact CG1-CZ 3.45Å; V288-F402 HydrophobicContact CG2-CE1 3.97Å; V288-F402 HydrophobicContact CG2-CZ 4.37Å; A347-F402 HydrophobicContact CB-CD1 3.93Å; A347-F402 HydrophobicContact CB-CE1 3.35Å; A347-F402 HydrophobicContact CB-CZ 3.91Å; V351-F402 HydrophobicContact CG2-CE2 4.13Å; V351-F402 HydrophobicContact CG2-CZ 3.71Å; F402-M404 VanDerWaalsContact C-N 3.31Å; F402-M404 PolarHBondContact O-N 3.19Å; F402-T405 WeakPolarHBondContact CA-OG1 3.44Å; F402-T405 PolarHBondContact O-N 3.22Å; F402-T405 VanDerWaalsContact O-N 3.16Å; F402-T405 PolarHBondContact O-OG1 2.66Å; F402-A406 HydrophobicContact CE2-CB 4.04Å; F402-A406 HydrophobicContact CZ-CB 4.34Å; F402-A406 WeakPolarHBondContact O-CB 3.5Å; F402-A406 PolarHBondContact O-N 2.86Å
403	P	93.3	Very high	90.7	Very high	0 Å²	0	14.5 Å²	14.5	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-53.6	-42.9	174.1	-27.3	32.6	0	0	0	114.7	F343 L344 V346 A347 A399 Y400 T405 A406 V407	F343-P403 HydrophobicContact CB-CB 3.98Å; F343-P403 HydrophobicContact CB-CG 3.94Å; F343-P403 WeakPolarHBondContact O-CB 3.26Å; F343-P403 VanDerWaalsContact O-CG 3.27Å; F343-P403 WeakPolarHBondContact O-CG 3.47Å; L344-P403 HydrophobicContact CD2-CG 3.99Å; V346-P403 HydrophobicContact CB-CB 4.43Å; A347-P403 HydrophobicContact CB-CB 4.06Å; A347-P403 HydrophobicContact CB-CG 3.95Å; A399-P403 WeakPolarHBondContact O-CD 3.25Å; A399-P403 VanDerWaalsContact O-CG 3.23Å; A399-P403 WeakPolarHBondContact O-CG 3.34Å; Y400-P403 WeakPolarHBondContact O-CD 3.42Å; P403-T405 VanDerWaalsContact C-N 3.35Å; P403-T405 PolarHBondContact O-N 2.81Å; P403-A406 PolarHBondContact O-N 2.74Å; P403-V407 WeakPolarHBondContact O-CG2 3.44Å; P403-V407 PolarHBondContact O-N 3.12Å
404	M	93.5	Very high	91.5	Very high	15 Å²	15	14.9 Å²	14.9	7%	0.074	8%	0.076	C	C	.	.	H	α-helix	trans	-61.6	-44.6	178.6	-60.2	-75.8	-62.4	0	0	111	F343 Y378 Y400 T401 F402 A408 A433 A434 T437	F343-M404 HydrophobicContact CD1-SD 4.02Å; F343-M404 HydrophobicContact CE1-SD 3.58Å; F343-M404 VanDerWaalsContact CE1-SD 3.58Å; Y378-M404 HydrophobicContact CD2-SD 4.34Å; Y378-M404 HydrophobicContact CE2-CE 3.85Å; Y378-M404 HydrophobicContact CE2-SD 3.36Å; Y378-M404 WeakPolarHBondContact CE2-SD 3.32Å; Y378-M404 WeakPolarHBondContact OH-CE 3.17Å; Y400-M404 WeakPolarHBondContact O-CG 3.46Å; Y400-M404 PolarHBondContact O-N 3.02Å; T401-M404 PolarHBondContact O-N 2.98Å; F402-M404 VanDerWaalsContact C-N 3.31Å; F402-M404 PolarHBondContact O-N 3.19Å; M404-A408 WeakPolarHBondContact O-CB 3.4Å; M404-A408 PolarHBondContact O-N 3.34Å; M404-A433 HydrophobicContact CE-CB 3.83Å; M404-A434 HydrophobicContact CB-CB 3.93Å; M404-T437 HydrophobicContact CG-CG2 4.3Å
405	T	95.9	Very high	92.2	Very high	1 Å²	1	12.7 Å²	12.7	1%	0.006	6%	0.06	C	C	.	.	H	α-helix	trans	-68.5	-34.1	177.1	54	0	0	0	0	113.4	S156 Q157 M160 T401 F402 P403 A408 S409 A434	S156-T405 WeakPolarHBondContact CB-OG1 3.31Å; S156-T405 PolarHBondContact OG-OG1 3.41Å; Q157-T405 VanDerWaalsContact CD-CG2 3.45Å; Q157-T405 HydrophobicContact CG-CG2 3.79Å; M160-T405 HydrophobicContact SD-CG2 4.24Å; T401-T405 PolarHBondContact O-N 3.48Å; T401-T405 VanDerWaalsContact O-N 3.09Å; T401-T405 PolarHBondContact O-OG1 3.33Å; F402-T405 WeakPolarHBondContact CA-OG1 3.44Å; F402-T405 PolarHBondContact O-N 3.22Å; F402-T405 VanDerWaalsContact O-N 3.16Å; F402-T405 PolarHBondContact O-OG1 2.66Å; P403-T405 VanDerWaalsContact C-N 3.35Å; P403-T405 PolarHBondContact O-N 2.81Å; T405-A408 PolarHBondContact O-N 3.49Å; T405-S409 WeakPolarHBondContact O-CB 3.02Å; T405-S409 PolarHBondContact O-N 3.28Å; T405-S409 PolarHBondContact O-OG 3.46Å; T405-A434 HydrophobicContact CG2-CB 3.98Å
406	A	96.4	Very high	92.7	Very high	3 Å²	3	14.7 Å²	14.7	3%	0.025	7%	0.071	C	C	.	.	H	α-helix	trans	-66.3	-45.4	178.9	0	0	0	0	0	110.4	A350 V351 F402 P403 S409 A410	A350-A406 HydrophobicContact CB-CB 3.74Å; V351-A406 HydrophobicContact CG2-CB 4.09Å; F402-A406 HydrophobicContact CE2-CB 4.04Å; F402-A406 HydrophobicContact CZ-CB 4.34Å; F402-A406 WeakPolarHBondContact O-CB 3.5Å; F402-A406 PolarHBondContact O-N 2.86Å; P403-A406 PolarHBondContact O-N 2.74Å; A406-S409 PolarHBondContact O-N 3.47Å; A406-A410 PolarHBondContact O-N 3.09Å
407	V	96.6	Very high	93.4	Very high	1 Å²	1	18.8 Å²	18.8	1%	0.006	9%	0.088	C	C	.	.	H	α-helix	trans	-60.2	-51.3	173.4	175.8	0	0	0	0	110.7	V346 A350 S374 Y378 P403 S409 A410 T411 M430	V346-V407 HydrophobicContact CB-CG2 4.48Å; V346-V407 HydrophobicContact CG1-CG2 3.13Å; A350-V407 HydrophobicContact CB-CG2 4.37Å; S374-V407 WeakPolarHBondContact OG-CG2 3.26Å; Y378-V407 HydrophobicContact CD2-CB 4.2Å; Y378-V407 HydrophobicContact CD2-CG1 4.13Å; Y378-V407 HydrophobicContact CD2-CG2 3.82Å; Y378-V407 HydrophobicContact CE2-CB 4.5Å; Y378-V407 HydrophobicContact CE2-CG1 4.47Å; Y378-V407 HydrophobicContact CG-CG1 4.22Å; Y378-V407 HydrophobicContact CG-CG2 4.34Å; P403-V407 WeakPolarHBondContact O-CG2 3.44Å; P403-V407 PolarHBondContact O-N 3.12Å; V407-S409 VanDerWaalsContact C-N 3.27Å; V407-S409 PolarHBondContact O-N 2.89Å; V407-A410 PolarHBondContact O-N 3.27Å; V407-A410 VanDerWaalsContact O-N 3.1Å; V407-T411 WeakPolarHBondContact O-CB 3.5Å; V407-T411 PolarHBondContact O-N 2.86Å; V407-T411 PolarHBondContact O-OG1 3.27Å; V407-M430 HydrophobicContact CG1-SD 4.36Å
408	A	97.3	Very high	93.8	Very high	0 Å²	0	18.5 Å²	18.5	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-56.2	-43.7	179.8	0	0	0	0	0	111.8	M160 M404 T405 A410 T411 I412 M430 A434	M160-A408 HydrophobicContact CG-CB 4.17Å; M160-A408 HydrophobicContact SD-CB 3.58Å; M160-A408 VanDerWaalsContact SD-CB 3.58Å; M404-A408 WeakPolarHBondContact O-CB 3.4Å; M404-A408 PolarHBondContact O-N 3.34Å; T405-A408 PolarHBondContact O-N 3.49Å; A408-A410 PolarHBondContact O-N 3.45Å; A408-T411 PolarHBondContact O-N 3.28Å; A408-I412 WeakPolarHBondContact O-CD1 3.45Å; A408-I412 VanDerWaalsContact O-CG1 3.25Å; A408-I412 WeakPolarHBondContact O-CG1 3.32Å; A408-I412 PolarHBondContact O-N 2.81Å; A408-M430 HydrophobicContact CB-CB 4.02Å; A408-A434 HydrophobicContact CB-CB 4.23Å
409	S	95.8	Very high	93.7	Very high	2 Å²	2	23 Å²	23	1%	0.014	12%	0.121	C	C	.	.	H	α-helix	trans	-62.4	-42	177	-56.5	0	0	0	0	112.5	M160 T405 A406 V407 I412 K413	M160-S409 WeakPolarHBondContact CA-OG 3.36Å; M160-S409 WeakPolarHBondContact CB-OG 3.5Å; T405-S409 WeakPolarHBondContact O-CB 3.02Å; T405-S409 PolarHBondContact O-N 3.28Å; T405-S409 PolarHBondContact O-OG 3.46Å; A406-S409 PolarHBondContact O-N 3.47Å; V407-S409 VanDerWaalsContact C-N 3.27Å; V407-S409 PolarHBondContact O-N 2.89Å; S409-I412 PolarHBondContact O-N 3.25Å; S409-K413 PolarHBondContact O-N 3.47Å
410	A	97	Very high	94	Very high	0 Å²	0	23.5 Å²	23.5	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-67.5	-38.7	175.2	0	0	0	0	0	112	A350 M354 Y371 A406 V407 A408 K413 Y414	A350-A410 HydrophobicContact CB-CB 4.47Å; M354-A410 HydrophobicContact CG-CB 4.39Å; Y371-A410 HydrophobicContact CD2-CB 3.87Å; Y371-A410 HydrophobicContact CE2-CB 4.41Å; A406-A410 PolarHBondContact O-N 3.09Å; V407-A410 PolarHBondContact O-N 3.27Å; V407-A410 VanDerWaalsContact O-N 3.1Å; A408-A410 PolarHBondContact O-N 3.45Å; A410-K413 PolarHBondContact O-N 2.95Å; A410-Y414 WeakPolarHBondContact O-CB 3.23Å; A410-Y414 PolarHBondContact O-N 2.99Å
411	T	97.2	Very high	94.3	Very high	1 Å²	1	27.9 Å²	27.9	1%	0.006	16%	0.157	C	C	.	.	H	α-helix	trans	-63.8	-41.2	175.4	-56.7	0	0	0	0	112	Y371 V407 A408 K413 Y414 S415 L426 M430	Y371-T411 WeakPolarHBondContact CE2-OG1 3.35Å; V407-T411 WeakPolarHBondContact O-CB 3.5Å; V407-T411 PolarHBondContact O-N 2.86Å; V407-T411 PolarHBondContact O-OG1 3.27Å; A408-T411 PolarHBondContact O-N 3.28Å; T411-K413 VanDerWaalsContact C-N 3.31Å; T411-K413 PolarHBondContact O-N 3.3Å; T411-Y414 PolarHBondContact O-N 3.03Å; T411-S415 WeakPolarHBondContact O-CB 3.36Å; T411-S415 PolarHBondContact O-N 3.15Å; T411-L426 HydrophobicContact CG2-CB 4.33Å; T411-L426 HydrophobicContact CG2-CD2 4.06Å; T411-L426 HydrophobicContact CG2-CG 3.81Å; T411-M430 HydrophobicContact CG2-CG 4.39Å
412	I	95.8	Very high	94.3	Very high	0 Å²	0	31.6 Å²	31.6	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-58.1	-47.1	174.7	-68.5	158.5	0	0	0	109.7	M160 T163 L164 T167 E170 A408 S409 S415 D416 S427	M160-I412 HydrophobicContact CG-CD1 4.13Å; T163-I412 HydrophobicContact CG2-CB 4.15Å; T163-I412 HydrophobicContact CG2-CD1 4.47Å; T163-I412 HydrophobicContact CG2-CG2 3.8Å; L164-I412 HydrophobicContact CB-CD1 4.04Å; L164-I412 HydrophobicContact CD1-CD1 3.81Å; L164-I412 HydrophobicContact CD1-CG1 3.98Å; T167-I412 HydrophobicContact CG2-CG2 3.82Å; E170-I412 HydrophobicContact CG-CG2 3.99Å; A408-I412 WeakPolarHBondContact O-CD1 3.45Å; A408-I412 VanDerWaalsContact O-CG1 3.25Å; A408-I412 WeakPolarHBondContact O-CG1 3.32Å; A408-I412 PolarHBondContact O-N 2.81Å; S409-I412 PolarHBondContact O-N 3.25Å; I412-S415 PolarHBondContact O-N 3.1Å; I412-D416 PolarHBondContact O-N 3.01Å; I412-D416 VanDerWaalsContact O-N 3.15Å; I412-S427 WeakPolarHBondContact CG1-OG 3.39Å
413	K	94.4	Very high	94.3	Very high	61 Å²	61	31.9 Å²	31.9	27%	0.265	19%	0.19	S	C	.	.	H	α-helix	trans	-66.2	-36.9	177.1	-72.3	-55.2	-174.2	-159.3	0	113.5	T163 T167 F363 S409 A410 T411 S415 D416 E417	T163-K413 HydrophobicContact CG2-CD 4.27Å; T163-K413 HydrophobicContact CG2-CG 4.17Å; T167-K413 PolarHBondContact OG1-NZ 2.71Å; F363-K413 HydrophobicContact CD2-CB 4.23Å; F363-K413 HydrophobicContact CE2-CB 4.12Å; S409-K413 PolarHBondContact O-N 3.47Å; A410-K413 PolarHBondContact O-N 2.95Å; T411-K413 VanDerWaalsContact C-N 3.31Å; T411-K413 PolarHBondContact O-N 3.3Å; K413-S415 VanDerWaalsContact C-N 3.32Å; K413-S415 PolarHBondContact O-N 3.39Å; K413-D416 WeakPolarHBondContact O-CB 3.45Å; K413-D416 PolarHBondContact O-N 2.96Å; K413-E417 PolarHBondContact O-N 3.04Å
414	Y	96.2	Very high	94.3	Very high	36 Å²	36	35.1 Å²	35.1	14%	0.141	20%	0.204	C	C	.	.	H	α-helix	trans	-64.4	-37.3	172.4	-178.9	-104.5	0	0	0	112.3	F363 Y371 F372 A410 T411 D416 E417 V418 T423	F363-Y414 HydrophobicContact CD1-CD2 4.33Å; F363-Y414 AromaticContact CE1-CD2 3.69Å; F363-Y414 HydrophobicContact CE1-CD2 3.69Å; F363-Y414 HydrophobicContact CZ-CD2 4.34Å; Y371-Y414 HydrophobicContact CD1-CD1 4.4Å; Y371-Y414 AromaticContact CD1-CD2 3.79Å; Y371-Y414 HydrophobicContact CD1-CD2 3.79Å; Y371-Y414 HydrophobicContact CD1-CE2 4.29Å; Y371-Y414 AromaticContact CD1-CG 3.84Å; Y371-Y414 HydrophobicContact CD1-CG 3.84Å; Y371-Y414 AromaticContact CE1-CD1 3.5Å; Y371-Y414 HydrophobicContact CE1-CD1 3.5Å; Y371-Y414 AromaticContact CE1-CD2 3.72Å; Y371-Y414 HydrophobicContact CE1-CD2 3.72Å; Y371-Y414 AromaticContact CE1-CE1 3.98Å; Y371-Y414 HydrophobicContact CE1-CE1 3.98Å; Y371-Y414 HydrophobicContact CE1-CE2 4.16Å; Y371-Y414 AromaticContact CE1-CG 3.35Å; Y371-Y414 HydrophobicContact CE1-CG 3.35Å; Y371-Y414 AromaticContact CZ-CD1 3.84Å; Y371-Y414 AromaticContact CZ-CG 3.81Å; F372-Y414 HydrophobicContact CE2-CE2 4.41Å; F372-Y414 AromaticContact CZ-CE2 3.99Å; F372-Y414 HydrophobicContact CZ-CE2 3.99Å; F372-Y414 AromaticContact CZ-CZ 3.82Å; A410-Y414 WeakPolarHBondContact O-CB 3.23Å; A410-Y414 PolarHBondContact O-N 2.99Å; T411-Y414 PolarHBondContact O-N 3.03Å; Y414-D416 VanDerWaalsContact C-N 3.26Å; Y414-D416 PolarHBondContact O-N 3.29Å; Y414-E417 PolarHBondContact O-N 3.27Å; Y414-V418 HydrophobicContact CD2-CG2 4.38Å; Y414-V418 HydrophobicContact CE1-CB 4.23Å; Y414-V418 HydrophobicContact CE1-CG2 4.48Å; Y414-V418 HydrophobicContact CE2-CB 4.33Å; Y414-V418 HydrophobicContact CE2-CG2 3.72Å; Y414-V418 PolarHBondContact O-N 3.39Å; Y414-T423 HydrophobicContact CD1-CG2 4.03Å; Y414-T423 HydrophobicContact CE1-CG2 3.67Å
415	S	94.9	Very high	94.4	Very high	0 Å²	0	39.2 Å²	39.2	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-69	-24.8	177.4	-172.7	0	0	0	0	113.3	A169 T411 I412 K413 V418 T419 T423 K424	A169-S415 WeakPolarHBondContact CB-O 3.49Å; T411-S415 WeakPolarHBondContact O-CB 3.36Å; T411-S415 PolarHBondContact O-N 3.15Å; I412-S415 PolarHBondContact O-N 3.1Å; K413-S415 VanDerWaalsContact C-N 3.32Å; K413-S415 PolarHBondContact O-N 3.39Å; S415-V418 CarbonylContact O-C 3.59Å; S415-T419 WeakPolarHBondContact O-CA 3.48Å; S415-T423 PolarHBondContact OG-OG1 2.88Å; S415-K424 PolarHBondContact OG-N 3.46Å
416	D	92.9	Very high	94.4	Very high	62 Å²	62	41 Å²	41	33%	0.332	24%	0.235	S	C	.	.	H	α-helix	trans	-71.5	-40.7	173.4	-153.8	43.1	0	0	0	111.5	T167 E168 A169 I412 K413 Y414 T419	T167-D416 HydrophobicContact CG2-CB 3.47Å; T167-D416 VanDerWaalsContact CG2-CB 3.47Å; T167-D416 VanDerWaalsContact CG2-OD1 3.29Å; T167-D416 WeakPolarHBondContact CG2-OD1 3.22Å; E168-D416 PolarHBondContact N-OD1 3.07Å; A169-D416 HydrophobicContact CB-CB 4.41Å; A169-D416 PolarHBondContact N-OD1 3.32Å; I412-D416 PolarHBondContact O-N 3.01Å; I412-D416 VanDerWaalsContact O-N 3.15Å; K413-D416 WeakPolarHBondContact O-CB 3.45Å; K413-D416 PolarHBondContact O-N 2.96Å; Y414-D416 VanDerWaalsContact C-N 3.26Å; Y414-D416 PolarHBondContact O-N 3.29Å; D416-T419 WeakPolarHBondContact O-CG2 3.44Å
417	E	93	Very high	94.3	Very high	98 Å²	98	40.9 Å²	40.9	46%	0.458	23%	0.234	S	C	.	.	H	α-helix	trans	-76.1	-47.4	179.3	-179.3	66.4	-164.6	0	0	112	F363 R368 K413 Y414	F363-E417 HydrophobicContact CB-CB 4.09Å; F363-E417 HydrophobicContact CB-CG 4.02Å; F363-E417 HydrophobicContact CD1-CB 4.39Å; F363-E417 HydrophobicContact CD1-CG 4.33Å; F363-E417 HydrophobicContact CG-CB 4.4Å; R368-E417 IonicContact NH2-OE1 3.74Å; R368-E417 PolarHBondContact NH2-OE1 3.05Å; K413-E417 PolarHBondContact O-N 3.04Å; Y414-E417 PolarHBondContact O-N 3.27Å
418	V	92.8	Very high	94.3	Very high	51 Å²	51	43.6 Å²	43.6	31%	0.309	25%	0.25	S	S	.	.	S	Bend	trans	-108.5	78.5	179.2	-174	0	0	0	0	108	Y414 S415 G420 T423	Y414-V418 HydrophobicContact CD2-CG2 4.38Å; Y414-V418 HydrophobicContact CE1-CB 4.23Å; Y414-V418 HydrophobicContact CE1-CG2 4.48Å; Y414-V418 HydrophobicContact CE2-CB 4.33Å; Y414-V418 HydrophobicContact CE2-CG2 3.72Å; Y414-V418 PolarHBondContact O-N 3.39Å; S415-V418 CarbonylContact O-C 3.59Å; V418-G420 PolarHBondContact O-N 2.97Å; V418-G420 VanDerWaalsContact O-N 3.16Å; V418-T423 HydrophobicContact CG1-CG2 4.45Å; V418-T423 WeakPolarHBondContact O-CB 3.45Å; V418-T423 WeakPolarHBondContact O-CG2 3.38Å; V418-T423 PolarHBondContact O-OG1 3.47Å
419	T	87.5	Confident	94.2	Very high	99 Å²	99	47.4 Å²	47.4	61%	0.607	27%	0.273	S	S	*	.			trans	-68.1	113.6	-178.9	60.7	0	0	0	0	110.5	S415 D416	S415-T419 WeakPolarHBondContact O-CA 3.48Å; D416-T419 WeakPolarHBondContact O-CG2 3.44Å
420	G	91	Very high	94.2	Very high	30 Å²	30	47.9 Å²	47.9	31%	0.309	28%	0.275	S	S	.	.			trans	-156.7	159.6	176.6	0	0	0	0	0	110.6	V418 A422 T423 K424	V418-G420 PolarHBondContact O-N 2.97Å; V418-G420 VanDerWaalsContact O-N 3.16Å; G420-A422 VanDerWaalsContact C-N 3.26Å; G420-A422 PolarHBondContact O-N 2.85Å; G420-T423 PolarHBondContact N-OG1 2.9Å; G420-T423 PolarHBondContact O-N 2.98Å; G420-T423 PolarHBondContact O-OG1 3.47Å; G420-K424 WeakPolarHBondContact O-CG 3.11Å; G420-K424 PolarHBondContact O-N 3.44Å; G420-K424 VanDerWaalsContact O-N 3.1Å
421	V	92	Very high	94.1	Very high	114 Å²	114	48.2 Å²	48.2	69%	0.691	28%	0.278	S	S	*	.	H	α-helix	trans	-61.7	-40.5	177.9	178.5	0	0	0	0	110.4	T423 K424 I425	V421-T423 PolarHBondContact O-N 3.45Å; V421-K424 PolarHBondContact O-N 2.82Å; V421-I425 HydrophobicContact CG1-CD1 3.72Å; V421-I425 HydrophobicContact CG1-CG1 4.33Å; V421-I425 WeakPolarHBondContact O-CB 3.41Å; V421-I425 VanDerWaalsContact O-CG1 3.23Å; V421-I425 WeakPolarHBondContact O-CG1 3.35Å; V421-I425 PolarHBondContact O-N 3.29Å
422	A	93.8	Very high	94.1	Very high	78 Å²	78	50 Å²	50	65%	0.645	30%	0.296	S	S	*	.	H	α-helix	trans	-63.2	-41.4	178.5	0	0	0	0	0	113.1	G420 L426	G420-A422 VanDerWaalsContact C-N 3.26Å; G420-A422 PolarHBondContact O-N 2.85Å; A422-L426 WeakPolarHBondContact O-CB 3.44Å; A422-L426 PolarHBondContact O-N 3.45Å
423	T	93.9	Very high	94	Very high	17 Å²	17	51.3 Å²	51.3	10%	0.104	31%	0.307	C	S	.	.	H	α-helix	trans	-70.9	-38.8	-179.8	49.6	0	0	0	0	111.8	Y414 S415 V418 G420 V421 L426 S427	Y414-T423 HydrophobicContact CD1-CG2 4.03Å; Y414-T423 HydrophobicContact CE1-CG2 3.67Å; S415-T423 PolarHBondContact OG-OG1 2.88Å; V418-T423 HydrophobicContact CG1-CG2 4.45Å; V418-T423 WeakPolarHBondContact O-CB 3.45Å; V418-T423 WeakPolarHBondContact O-CG2 3.38Å; V418-T423 PolarHBondContact O-OG1 3.47Å; G420-T423 PolarHBondContact N-OG1 2.9Å; G420-T423 PolarHBondContact O-N 2.98Å; G420-T423 PolarHBondContact O-OG1 3.47Å; V421-T423 PolarHBondContact O-N 3.45Å; T423-L426 PolarHBondContact O-N 2.77Å; T423-S427 WeakPolarHBondContact O-CB 3.38Å; T423-S427 PolarHBondContact O-N 2.88Å
424	K	93.4	Very high	94.1	Very high	68 Å²	68	48.4 Å²	48.4	30%	0.296	30%	0.295	S	S	.	.	H	α-helix	trans	-62.9	-46.4	172.4	-69.3	179.4	-179.8	-165.7	0	112.1	A169 F172 S415 G420 V421 L426 S427 V428	A169-K424 VanDerWaalsContact O-CE 3.23Å; A169-K424 WeakPolarHBondContact O-CE 3.32Å; A169-K424 PolarHBondContact O-NZ 2.85Å; F172-K424 HydrophobicContact CD1-CD 4.28Å; F172-K424 HydrophobicContact CE1-CB 4.15Å; F172-K424 HydrophobicContact CE1-CD 3.85Å; F172-K424 HydrophobicContact CE1-CG 4.09Å; F172-K424 HydrophobicContact CZ-CB 4.19Å; S415-K424 PolarHBondContact OG-N 3.46Å; G420-K424 WeakPolarHBondContact O-CG 3.11Å; G420-K424 PolarHBondContact O-N 3.44Å; G420-K424 VanDerWaalsContact O-N 3.1Å; V421-K424 PolarHBondContact O-N 2.82Å; K424-L426 VanDerWaalsContact C-N 3.3Å; K424-L426 PolarHBondContact O-N 3.4Å; K424-S427 WeakPolarHBondContact O-CB 3.48Å; K424-S427 PolarHBondContact O-N 3.07Å; K424-V428 WeakPolarHBondContact O-CG2 3.42Å; K424-V428 PolarHBondContact O-N 3.31Å
425	I	95.3	Very high	94.1	Very high	101 Å²	101	48.1 Å²	48.1	52%	0.518	30%	0.297	S	S	.	.	H	α-helix	trans	-58.6	-46.5	175.1	-69.9	168.3	0	0	0	109.9	V421 S427 V428 V429	V421-I425 HydrophobicContact CG1-CD1 3.72Å; V421-I425 HydrophobicContact CG1-CG1 4.33Å; V421-I425 WeakPolarHBondContact O-CB 3.41Å; V421-I425 VanDerWaalsContact O-CG1 3.23Å; V421-I425 WeakPolarHBondContact O-CG1 3.35Å; V421-I425 PolarHBondContact O-N 3.29Å; I425-S427 VanDerWaalsContact C-N 3.35Å; I425-S427 PolarHBondContact O-N 3.49Å; I425-V428 PolarHBondContact O-N 2.78Å; I425-V429 HydrophobicContact CG2-CG2 4.19Å; I425-V429 WeakPolarHBondContact O-CB 3.25Å; I425-V429 VanDerWaalsContact O-CG2 3.24Å; I425-V429 WeakPolarHBondContact O-CG2 3.33Å; I425-V429 PolarHBondContact O-N 2.91Å
426	L	95.3	Very high	94.1	Very high	40 Å²	40	53.9 Å²	53.9	21%	0.209	33%	0.327	C	S	.	.	H	α-helix	trans	-60.6	-44.4	179.1	-177.1	62.9	0	0	0	111.7	L375 F379 T411 A422 T423 K424 V428 V429 M430	L375-L426 HydrophobicContact CD1-CD2 4.41Å; L375-L426 HydrophobicContact CD2-CD2 4.41Å; F379-L426 HydrophobicContact CZ-CD1 3.89Å; T411-L426 HydrophobicContact CG2-CB 4.33Å; T411-L426 HydrophobicContact CG2-CD2 4.06Å; T411-L426 HydrophobicContact CG2-CG 3.81Å; A422-L426 WeakPolarHBondContact O-CB 3.44Å; A422-L426 PolarHBondContact O-N 3.45Å; T423-L426 PolarHBondContact O-N 2.77Å; K424-L426 VanDerWaalsContact C-N 3.3Å; K424-L426 PolarHBondContact O-N 3.4Å; L426-V428 PolarHBondContact O-N 2.96Å; L426-V429 PolarHBondContact O-N 3.29Å; L426-M430 HydrophobicContact CD1-CE 4.13Å; L426-M430 HydrophobicContact CD1-CG 4.07Å; L426-M430 HydrophobicContact CG-CG 4.3Å; L426-M430 WeakPolarHBondContact O-CB 3.43Å; L426-M430 WeakPolarHBondContact O-CG 3.25Å; L426-M430 PolarHBondContact O-N 3.43Å
427	S	94.7	Very high	94.1	Very high	0 Å²	0	52.4 Å²	52.4	0%	0	32%	0.32	C	S	.	.	H	α-helix	trans	-57.7	-47	176.1	176.5	0	0	0	0	112.4	E170 I412 T423 K424 I425 M430 S431	E170-S427 WeakPolarHBondContact OE1-CB 3.26Å; E170-S427 PolarHBondContact OE1-OG 3.37Å; I412-S427 WeakPolarHBondContact CG1-OG 3.39Å; T423-S427 WeakPolarHBondContact O-CB 3.38Å; T423-S427 PolarHBondContact O-N 2.88Å; K424-S427 WeakPolarHBondContact O-CB 3.48Å; K424-S427 PolarHBondContact O-N 3.07Å; I425-S427 VanDerWaalsContact C-N 3.35Å; I425-S427 PolarHBondContact O-N 3.49Å; S427-M430 PolarHBondContact O-N 3.11Å; S427-S431 VanDerWaalsContact O-CB 3.29Å; S427-S431 WeakPolarHBondContact O-CB 3.49Å; S427-S431 PolarHBondContact O-N 3.43Å; S427-S431 PolarHBondContact O-OG 3.37Å
428	V	95.2	Very high	94.2	Very high	58 Å²	58	48.3 Å²	48.3	35%	0.352	30%	0.302	S	S	.	.	H	α-helix	trans	-62.8	-46.7	176	173.3	0	0	0	0	111.4	F172 L173 K424 I425 L426 S431 G432	F172-V428 HydrophobicContact CE2-CG2 4.37Å; F172-V428 HydrophobicContact CZ-CG2 3.93Å; L173-V428 HydrophobicContact CD1-CG2 3.89Å; L173-V428 HydrophobicContact CD2-CG2 3.93Å; L173-V428 HydrophobicContact CG-CG2 4.35Å; K424-V428 WeakPolarHBondContact O-CG2 3.42Å; K424-V428 PolarHBondContact O-N 3.31Å; I425-V428 PolarHBondContact O-N 2.78Å; L426-V428 PolarHBondContact O-N 2.96Å; V428-S431 PolarHBondContact O-N 2.82Å; V428-G432 PolarHBondContact O-N 3.32Å
429	V	95.8	Very high	94.2	Very high	80 Å²	80	51 Å²	51	49%	0.485	31%	0.314	S	S	.	.	H	α-helix	trans	-63.8	-44.1	-179.3	173.3	0	0	0	0	110.9	I425 L426 G432 A433	I425-V429 HydrophobicContact CG2-CG2 4.19Å; I425-V429 WeakPolarHBondContact O-CB 3.25Å; I425-V429 VanDerWaalsContact O-CG2 3.24Å; I425-V429 WeakPolarHBondContact O-CG2 3.33Å; I425-V429 PolarHBondContact O-N 2.91Å; L426-V429 PolarHBondContact O-N 3.29Å; V429-G432 PolarHBondContact O-N 3.45Å; V429-A433 WeakPolarHBondContact O-CB 3.29Å; V429-A433 PolarHBondContact O-N 2.97Å
430	M	95.4	Very high	94.5	Very high	11 Å²	11	48.8 Å²	48.8	5%	0.054	31%	0.305	C	S	.	.	H	α-helix	trans	-66.1	-42.8	178.1	-67.1	-60.6	99.8	0	0	111.8	Y378 F379 V407 A408 T411 L426 S427 A433 A434	Y378-M430 HydrophobicContact CD1-SD 3.93Å; Y378-M430 HydrophobicContact CE1-CE 3.74Å; Y378-M430 HydrophobicContact CE1-SD 3.23Å; Y378-M430 WeakPolarHBondContact CE1-SD 3.18Å; Y378-M430 HydrophobicContact CE2-SD 4.36Å; F379-M430 HydrophobicContact CE1-CE 4.49Å; V407-M430 HydrophobicContact CG1-SD 4.36Å; A408-M430 HydrophobicContact CB-CB 4.02Å; T411-M430 HydrophobicContact CG2-CG 4.39Å; L426-M430 HydrophobicContact CD1-CE 4.13Å; L426-M430 HydrophobicContact CD1-CG 4.07Å; L426-M430 HydrophobicContact CG-CG 4.3Å; L426-M430 WeakPolarHBondContact O-CB 3.43Å; L426-M430 WeakPolarHBondContact O-CG 3.25Å; L426-M430 PolarHBondContact O-N 3.43Å; S427-M430 PolarHBondContact O-N 3.11Å; M430-A433 PolarHBondContact O-N 2.93Å; M430-A434 WeakPolarHBondContact O-CB 3.5Å; M430-A434 PolarHBondContact O-N 3.45Å
431	S	95.9	Very high	94.6	Very high	7 Å²	7	47.6 Å²	47.6	5%	0.049	29%	0.292	C	S	.	.	H	α-helix	trans	-65.3	-40	177	-59.1	0	0	0	0	111.9	S427 V428 A434 T435	S427-S431 VanDerWaalsContact O-CB 3.29Å; S427-S431 WeakPolarHBondContact O-CB 3.49Å; S427-S431 PolarHBondContact O-N 3.43Å; S427-S431 PolarHBondContact O-OG 3.37Å; V428-S431 PolarHBondContact O-N 2.82Å; S431-A434 PolarHBondContact O-N 3.03Å; S431-T435 WeakPolarHBondContact O-CB 3.34Å; S431-T435 PolarHBondContact O-N 2.97Å; S431-T435 PolarHBondContact O-OG1 3.33Å
432	G	96.1	Very high	94.6	Very high	39 Å²	39	45.8 Å²	45.8	40%	0.402	28%	0.278	S	S	.	.	H	α-helix	trans	-62.5	-46.3	173.1	0	0	0	0	0	111.9	V428 V429 T435 L436	V428-G432 PolarHBondContact O-N 3.32Å; V429-G432 PolarHBondContact O-N 3.45Å; G432-T435 PolarHBondContact O-N 3.07Å; G432-L436 VanDerWaalsContact O-CB 3.31Å; G432-L436 WeakPolarHBondContact O-CB 3.39Å; G432-L436 PolarHBondContact O-N 3.41Å
433	A	95.2	Very high	94.6	Very high	28 Å²	28	44 Å²	44	23%	0.231	27%	0.267	C	S	.	.	H	α-helix	trans	-62.6	-43.6	176.4	0	0	0	0	0	112.2	M404 V429 M430 L436 T437	M404-A433 HydrophobicContact CE-CB 3.83Å; V429-A433 WeakPolarHBondContact O-CB 3.29Å; V429-A433 PolarHBondContact O-N 2.97Å; M430-A433 PolarHBondContact O-N 2.93Å; A433-L436 PolarHBondContact O-N 2.93Å; A433-T437 WeakPolarHBondContact O-CB 3.21Å; A433-T437 PolarHBondContact O-N 3.38Å; A433-T437 PolarHBondContact O-OG1 2.87Å
434	A	95.9	Very high	94.5	Very high	0 Å²	0	45.9 Å²	45.9	0%	0	28%	0.276	C	S	.	.	H	α-helix	trans	-61.5	-46.4	176.3	0	0	0	0	0	111.7	Q157 M160 M404 T405 A408 M430 S431 T437 V438	Q157-A434 VanDerWaalsContact NE2-C 3.25Å; Q157-A434 PolarHBondContact NE2-O 2.83Å; M160-A434 HydrophobicContact SD-CB 3.8Å; M404-A434 HydrophobicContact CB-CB 3.93Å; T405-A434 HydrophobicContact CG2-CB 3.98Å; A408-A434 HydrophobicContact CB-CB 4.23Å; M430-A434 WeakPolarHBondContact O-CB 3.5Å; M430-A434 PolarHBondContact O-N 3.45Å; S431-A434 PolarHBondContact O-N 3.03Å; A434-T437 PolarHBondContact O-N 3.37Å; A434-V438 PolarHBondContact O-N 2.93Å
435	T	95.7	Very high	94.4	Very high	30 Å²	30	43 Å²	43	18%	0.184	27%	0.265	C	S	.	.	H	α-helix	trans	-61.8	-47.9	177.7	-56.9	0	0	0	0	111.2	W161 S431 G432 T437 V438 I439	W161-T435 HydrophobicContact CZ2-CG2 4.21Å; S431-T435 WeakPolarHBondContact O-CB 3.34Å; S431-T435 PolarHBondContact O-N 2.97Å; S431-T435 PolarHBondContact O-OG1 3.33Å; G432-T435 PolarHBondContact O-N 3.07Å; T435-T437 VanDerWaalsContact C-N 3.3Å; T435-T437 PolarHBondContact O-N 2.91Å; T435-V438 PolarHBondContact O-N 3.25Å; T435-I439 HydrophobicContact CG2-CD1 3.76Å; T435-I439 HydrophobicContact CG2-CG1 4.43Å; T435-I439 WeakPolarHBondContact O-CG1 3.31Å; T435-I439 PolarHBondContact O-N 3.31Å
436	L	95.8	Very high	94.2	Very high	120 Å²	120	41.6 Å²	41.6	63%	0.628	26%	0.26	S	S	*	.	H	α-helix	trans	-59.8	-41.3	177	-178.5	62.5	0	0	0	111.8	G432 A433 I439 A440	G432-L436 VanDerWaalsContact O-CB 3.31Å; G432-L436 WeakPolarHBondContact O-CB 3.39Å; G432-L436 PolarHBondContact O-N 3.41Å; A433-L436 PolarHBondContact O-N 2.93Å; L436-I439 PolarHBondContact O-N 3.45Å; L436-A440 VanDerWaalsContact O-CB 3.25Å; L436-A440 WeakPolarHBondContact O-CB 3.48Å; L436-A440 PolarHBondContact O-N 3.26Å
437	T	92.8	Very high	94	Very high	31 Å²	31	43.1 Å²	43.1	19%	0.19	27%	0.267	C	S	.	.	H	α-helix	trans	-61.4	-46.6	177.7	-55.6	0	0	0	0	111.2	T401 M404 A433 A434 T435 A440 V441	T401-T437 HydrophobicContact CG2-CG2 4.34Å; M404-T437 HydrophobicContact CG-CG2 4.3Å; A433-T437 WeakPolarHBondContact O-CB 3.21Å; A433-T437 PolarHBondContact O-N 3.38Å; A433-T437 PolarHBondContact O-OG1 2.87Å; A434-T437 PolarHBondContact O-N 3.37Å; T435-T437 VanDerWaalsContact C-N 3.3Å; T435-T437 PolarHBondContact O-N 2.91Å; T437-A440 PolarHBondContact O-N 2.87Å; T437-V441 HydrophobicContact CG2-CG2 4.43Å; T437-V441 WeakPolarHBondContact O-CB 3.41Å; T437-V441 VanDerWaalsContact O-CG2 3.25Å; T437-V441 WeakPolarHBondContact O-CG2 3.48Å; T437-V441 PolarHBondContact O-N 3.46Å
438	V	94.2	Very high	93.7	Very high	13 Å²	13	44.1 Å²	44.1	8%	0.079	27%	0.272	C	S	.	.	H	α-helix	trans	-66.2	-43.7	178.1	170.3	0	0	0	0	111.8	Q157 W398 T401 A434 T435 A440 V441 L442	Q157-V438 HydrophobicContact CG-CB 4.05Å; Q157-V438 HydrophobicContact CG-CG1 4.06Å; Q157-V438 HydrophobicContact CG-CG2 3.62Å; W398-V438 HydrophobicContact CZ3-CG1 4.42Å; T401-V438 HydrophobicContact CG2-CB 4.43Å; T401-V438 HydrophobicContact CG2-CG2 3.57Å; A434-V438 PolarHBondContact O-N 2.93Å; T435-V438 PolarHBondContact O-N 3.25Å; V438-A440 VanDerWaalsContact C-N 3.33Å; V438-A440 PolarHBondContact O-N 3.31Å; V438-V441 PolarHBondContact O-N 3.5Å; V438-L442 WeakPolarHBondContact O-CB 3.44Å; V438-L442 PolarHBondContact O-N 3.15Å
439	I	94.4	Very high	93.4	Very high	108 Å²	108	42.9 Å²	42.9	55%	0.554	27%	0.268	S	S	*	.	H	α-helix	trans	-61.2	-44.1	177.8	-69.1	171.7	0	0	0	110.7	T435 L436 G443	T435-I439 HydrophobicContact CG2-CD1 3.76Å; T435-I439 HydrophobicContact CG2-CG1 4.43Å; T435-I439 WeakPolarHBondContact O-CG1 3.31Å; T435-I439 PolarHBondContact O-N 3.31Å; L436-I439 PolarHBondContact O-N 3.45Å; I439-G443 PolarHBondContact O-N 2.89Å
440	A	93.2	Very high	93.1	Very high	51 Å²	51	46.3 Å²	46.3	42%	0.421	28%	0.277	S	S	.	.	H	α-helix	trans	-63.9	-49.3	178.7	0	0	0	0	0	111.6	L436 T437 V438 L442 G443 L444	L436-A440 VanDerWaalsContact O-CB 3.25Å; L436-A440 WeakPolarHBondContact O-CB 3.48Å; L436-A440 PolarHBondContact O-N 3.26Å; T437-A440 PolarHBondContact O-N 2.87Å; V438-A440 VanDerWaalsContact C-N 3.33Å; V438-A440 PolarHBondContact O-N 3.31Å; A440-L442 PolarHBondContact O-N 3.22Å; A440-G443 PolarHBondContact O-N 2.81Å; A440-L444 WeakPolarHBondContact O-CG 3.46Å; A440-L444 PolarHBondContact O-N 2.93Å
441	V	92.4	Very high	92.7	Very high	5 Å²	5	51.2 Å²	51.2	3%	0.03	31%	0.307	C	S	.	.	H	α-helix	trans	-64.2	-41.3	179	173.7	0	0	0	0	111	F393 W397 W398 T401 T437 V438 L444 T445	F393-V441 HydrophobicContact CE2-CG1 4.34Å; W397-V441 HydrophobicContact CB-CG1 4.31Å; W397-V441 HydrophobicContact CB-CG2 4.31Å; W398-V441 HydrophobicContact CD2-CG1 3.65Å; W398-V441 HydrophobicContact CE3-CG1 4.24Å; W398-V441 HydrophobicContact CG-CG1 3.83Å; W398-V441 HydrophobicContact CZ2-CG1 4.14Å; T401-V441 HydrophobicContact CG2-CB 4.16Å; T401-V441 HydrophobicContact CG2-CG1 4.32Å; T401-V441 HydrophobicContact CG2-CG2 4.17Å; T437-V441 HydrophobicContact CG2-CG2 4.43Å; T437-V441 WeakPolarHBondContact O-CB 3.41Å; T437-V441 VanDerWaalsContact O-CG2 3.25Å; T437-V441 WeakPolarHBondContact O-CG2 3.48Å; T437-V441 PolarHBondContact O-N 3.46Å; V438-V441 PolarHBondContact O-N 3.5Å; V441-L444 PolarHBondContact O-N 3.24Å; V441-T445 WeakPolarHBondContact O-CB 3.34Å; V441-T445 PolarHBondContact O-N 3.41Å; V441-T445 PolarHBondContact O-OG1 3.33Å
442	L	92.9	Very high	92.1	Very high	77 Å²	77	55.5 Å²	55.5	40%	0.403	33%	0.326	S	S	.	.	H	α-helix	trans	-65.3	-45	176.5	-178.4	63.3	0	0	0	111.6	W398 V438 A440 L444 T445 V446	W398-L442 HydrophobicContact CH2-CB 4.12Å; W398-L442 HydrophobicContact CH2-CD1 4.04Å; W398-L442 HydrophobicContact CZ2-CB 4.24Å; W398-L442 HydrophobicContact CZ2-CD1 3.96Å; V438-L442 WeakPolarHBondContact O-CB 3.44Å; V438-L442 PolarHBondContact O-N 3.15Å; A440-L442 PolarHBondContact O-N 3.22Å; L442-L444 VanDerWaalsContact C-N 3.34Å; L442-L444 PolarHBondContact O-N 3.5Å; L442-T445 WeakPolarHBondContact O-CB 3.25Å; L442-T445 PolarHBondContact O-N 2.87Å; L442-T445 VanDerWaalsContact O-N 3.12Å; L442-V446 HydrophobicContact CD1-CG2 4.41Å; L442-V446 WeakPolarHBondContact O-CG2 3.28Å; L442-V446 PolarHBondContact O-N 3.49Å
443	G	93.1	Very high	91.5	Very high	41 Å²	41	63.6 Å²	63.6	42%	0.423	35%	0.345	S	S	.	.	H	α-helix	trans	-59.7	-43.6	176.9	0	0	0	0	0	112.3	I439 A440 V446 M447	I439-G443 PolarHBondContact O-N 2.89Å; A440-G443 PolarHBondContact O-N 2.81Å; G443-V446 PolarHBondContact O-N 3.47Å; G443-M447 WeakPolarHBondContact O-CB 3.44Å; G443-M447 PolarHBondContact O-N 2.85Å
444	L	91.5	Very high	90.9	Very high	55 Å²	55	65.6 Å²	65.6	29%	0.288	35%	0.351	S	S	.	.	H	α-helix	trans	-64.2	-41.3	172.5	-68.8	172.9	0	0	0	111.7	F393 W397 A440 V441 L442 V446 M447 H448	F393-L444 HydrophobicContact CD2-CB 3.52Å; F393-L444 HydrophobicContact CD2-CD1 3.81Å; F393-L444 HydrophobicContact CD2-CG 4.28Å; F393-L444 HydrophobicContact CE2-CB 3.62Å; F393-L444 HydrophobicContact CE2-CD1 4.42Å; F393-L444 HydrophobicContact CG-CB 4.02Å; F393-L444 HydrophobicContact CZ-CB 4.21Å; W397-L444 HydrophobicContact CE3-CD1 4.26Å; W397-L444 HydrophobicContact CZ3-CD1 3.99Å; A440-L444 WeakPolarHBondContact O-CG 3.46Å; A440-L444 PolarHBondContact O-N 2.93Å; V441-L444 PolarHBondContact O-N 3.24Å; L442-L444 VanDerWaalsContact C-N 3.34Å; L442-L444 PolarHBondContact O-N 3.5Å; L444-V446 PolarHBondContact O-N 2.88Å; L444-M447 HydrophobicContact CD2-CE 4.01Å; L444-M447 PolarHBondContact O-N 3.31Å; L444-H448 WeakPolarHBondContact O-CB 3.34Å; L444-H448 PolarHBondContact O-CD2 2.87Å; L444-H448 VanDerWaalsContact O-CD2 3.28Å; L444-H448 PolarHBondContact O-N 2.84Å
445	T	92.2	Very high	90.3	Very high	9 Å²	9	66.8 Å²	66.8	6%	0.055	36%	0.357	C	S	.	.	H	α-helix	trans	-59.1	-46.2	176.3	-55.4	0	0	0	0	111.1	M150 F393 W398 V441 L442 H448 A449 L455	M150-T445 HydrophobicContact SD-CG2 4.2Å; F393-T445 WeakPolarHBondContact CZ-OG1 3.35Å; W398-T445 PolarHBondContact NE1-OG1 3.45Å; V441-T445 WeakPolarHBondContact O-CB 3.34Å; V441-T445 PolarHBondContact O-N 3.41Å; V441-T445 PolarHBondContact O-OG1 3.33Å; L442-T445 WeakPolarHBondContact O-CB 3.25Å; L442-T445 PolarHBondContact O-N 2.87Å; L442-T445 VanDerWaalsContact O-N 3.12Å; T445-H448 PolarHBondContact O-N 3.28Å; T445-A449 WeakPolarHBondContact O-CB 3.44Å; T445-A449 PolarHBondContact O-N 3.32Å; T445-L455 HydrophobicContact CG2-CD1 4.1Å; T445-L455 HydrophobicContact CG2-CD2 3.88Å
446	V	91.1	Very high	89.8	Confident	71 Å²	71	66.7 Å²	66.7	43%	0.43	36%	0.355	S	S	.	.	H	α-helix	trans	-64.6	-43.6	178.1	170.3	0	0	0	0	110.8	L442 G443 L444 A449 F450	L442-V446 HydrophobicContact CD1-CG2 4.41Å; L442-V446 WeakPolarHBondContact O-CG2 3.28Å; L442-V446 PolarHBondContact O-N 3.49Å; G443-V446 PolarHBondContact O-N 3.47Å; L444-V446 PolarHBondContact O-N 2.88Å; V446-A449 PolarHBondContact O-N 3.5Å; V446-F450 HydrophobicContact CB-CD2 4.47Å; V446-F450 HydrophobicContact CG1-CD2 3.8Å; V446-F450 HydrophobicContact CG1-CE2 4.27Å; V446-F450 WeakPolarHBondContact O-CD2 3.39Å; V446-F450 PolarHBondContact O-N 2.71Å
447	M	90.8	Very high	89.3	Confident	71 Å²	71	65.2 Å²	65.2	35%	0.35	35%	0.352	S	S	.	.	I	π-helix	trans	-60	-48.2	176.2	-173.6	-168.2	66.7	0	0	111.5	G443 L444 V451 Q452	G443-M447 WeakPolarHBondContact O-CB 3.44Å; G443-M447 PolarHBondContact O-N 2.85Å; L444-M447 HydrophobicContact CD2-CE 4.01Å; L444-M447 PolarHBondContact O-N 3.31Å; M447-V451 HydrophobicContact CG-CB 4.31Å; M447-V451 HydrophobicContact CG-CG2 4.3Å; M447-V451 WeakPolarHBondContact O-CA 3.37Å; M447-V451 WeakPolarHBondContact O-CB 3.38Å; M447-V451 PolarHBondContact O-N 3.42Å; M447-Q452 PolarHBondContact O-N 3.16Å; M447-Q452 VanDerWaalsContact O-N 3.11Å
448	H	88	Confident	88.8	Confident	21 Å²	21	65.5 Å²	65.5	10%	0.097	35%	0.353	C	S	.	.	I	π-helix	trans	-69	-32.5	178.5	-82.7	-86.6	0	0	0	112.8	F393 L444 T445 Q452 R453 D454 L455	F393-H448 HydrophobicContact CD1-CB 4.04Å; F393-H448 AromaticContact CD1-CD2 3.28Å; F393-H448 WeakPolarHBondContact CD1-CD2 3.37Å; F393-H448 AromaticContact CD1-CG 3.58Å; F393-H448 AromaticContact CD1-NE2 3.83Å; F393-H448 HydrophobicContact CE1-CB 4.1Å; F393-H448 AromaticContact CG-CD2 3.77Å; L444-H448 WeakPolarHBondContact O-CB 3.34Å; L444-H448 PolarHBondContact O-CD2 2.87Å; L444-H448 VanDerWaalsContact O-CD2 3.28Å; L444-H448 PolarHBondContact O-N 2.84Å; T445-H448 PolarHBondContact O-N 3.28Å; H448-Q452 PolarHBondContact CE1-OE1 2.87Å; H448-Q452 PolarHBondContact ND1-OE1 3.44Å; H448-Q452 VanDerWaalsContact ND1-OE1 3.14Å; H448-R453 WeakPolarHBondContact O-CA 3.27Å; H448-R453 PolarHBondContact O-N 3.03Å; H448-D454 WeakPolarHBondContact CB-OD1 3.35Å; H448-D454 IonicContact CE1-OD1 2.77Å; H448-D454 IonicContact CE1-OD2 3.01Å; H448-D454 IonicContact CG-OD1 3.52Å; H448-D454 VanDerWaalsContact ND1-CG 3.26Å; H448-D454 IonicContact ND1-OD1 3.42Å; H448-D454 PolarHBondContact ND1-OD1 3.41Å; H448-D454 IonicContact ND1-OD2 3.03Å; H448-D454 PolarHBondContact ND1-OD2 3.04Å; H448-D454 PolarHBondContact O-N 3.07Å; H448-L455 HydrophobicContact CB-CB 4.43Å; H448-L455 HydrophobicContact CB-CD1 4.36Å
449	A	88.3	Confident	88.3	Confident	33 Å²	33	65.5 Å²	65.5	27%	0.273	35%	0.352	S	S	.	.	I	π-helix	trans	-68.9	-51.2	176.4	0	0	0	0	0	112.7	T445 V446 L455	T445-A449 WeakPolarHBondContact O-CB 3.44Å; T445-A449 PolarHBondContact O-N 3.32Å; V446-A449 PolarHBondContact O-N 3.5Å; A449-L455 HydrophobicContact CB-CB 4.42Å; A449-L455 HydrophobicContact CB-CD2 3.8Å
450	F	89.9	Confident	87.6	Confident	152 Å²	152	61.9 Å²	61.9	67%	0.667	34%	0.335	S	S	*	.	I	π-helix	trans	-100.8	-34.1	-167.2	-65.5	-72.5	0	0	0	113.7	V446	V446-F450 HydrophobicContact CB-CD2 4.47Å; V446-F450 HydrophobicContact CG1-CD2 3.8Å; V446-F450 HydrophobicContact CG1-CE2 4.27Å; V446-F450 WeakPolarHBondContact O-CD2 3.39Å; V446-F450 PolarHBondContact O-N 2.71Å
451	V	87.8	Confident	86.8	Confident	113 Å²	113	59.6 Å²	59.6	69%	0.685	32%	0.315	S	S	*	.	I	π-helix	trans	-90.3	-55.9	-176.9	-172.7	0	0	0	0	110.3	M447	M447-V451 HydrophobicContact CG-CB 4.31Å; M447-V451 HydrophobicContact CG-CG2 4.3Å; M447-V451 WeakPolarHBondContact O-CA 3.37Å; M447-V451 WeakPolarHBondContact O-CB 3.38Å; M447-V451 PolarHBondContact O-N 3.42Å
452	Q	83.4	Confident	86	Confident	97 Å²	97	59.4 Å²	59.4	45%	0.453	31%	0.314	S	S	.	.	I	π-helix	trans	-85	-25.1	-176.4	-58.3	-173.2	21.5	0	0	112.8	M447 H448 D454	M447-Q452 PolarHBondContact O-N 3.16Å; M447-Q452 VanDerWaalsContact O-N 3.11Å; H448-Q452 PolarHBondContact CE1-OE1 2.87Å; H448-Q452 PolarHBondContact ND1-OE1 3.44Å; H448-Q452 VanDerWaalsContact ND1-OE1 3.14Å; Q452-D454 HydrophobicContact CB-CB 4.43Å; Q452-D454 VanDerWaalsContact CB-OD1 3.28Å; Q452-D454 WeakPolarHBondContact CB-OD1 3.29Å; Q452-D454 PolarHBondContact O-N 2.91Å; Q452-D454 PolarHBondContact OE1-OD2 3.35Å
453	R	82.9	Confident	85.2	Confident	210 Å²	210	55.7 Å²	55.7	79%	0.792	30%	0.295	S	S	*	.			trans	56.1	28.5	-177.8	-58.1	-178.8	178.7	145.8	-1.4	113.5	H448	H448-R453 WeakPolarHBondContact O-CA 3.27Å; H448-R453 PolarHBondContact O-N 3.03Å
454	D	83.1	Confident	84.2	Confident	70 Å²	70	53.8 Å²	53.8	37%	0.374	28%	0.275	S	S	.	.			trans	-109.8	1.6	-176.5	70	-23.3	0	0	0	112.9	H448 Q452 F456 P457	H448-D454 WeakPolarHBondContact CB-OD1 3.35Å; H448-D454 IonicContact CE1-OD1 2.77Å; H448-D454 IonicContact CE1-OD2 3.01Å; H448-D454 IonicContact CG-OD1 3.52Å; H448-D454 VanDerWaalsContact ND1-CG 3.26Å; H448-D454 IonicContact ND1-OD1 3.42Å; H448-D454 PolarHBondContact ND1-OD1 3.41Å; H448-D454 IonicContact ND1-OD2 3.03Å; H448-D454 PolarHBondContact ND1-OD2 3.04Å; H448-D454 PolarHBondContact O-N 3.07Å; Q452-D454 HydrophobicContact CB-CB 4.43Å; Q452-D454 VanDerWaalsContact CB-OD1 3.28Å; Q452-D454 WeakPolarHBondContact CB-OD1 3.29Å; Q452-D454 PolarHBondContact O-N 2.91Å; Q452-D454 PolarHBondContact OE1-OD2 3.35Å; D454-F456 PolarHBondContact O-N 3Å; D454-F456 VanDerWaalsContact O-N 3.15Å; D454-P457 WeakPolarHBondContact O-CD 3.22Å
455	L	83.3	Confident	83	Confident	24 Å²	24	51.9 Å²	51.9	13%	0.126	27%	0.266	C	S	.	.	S	Bend	trans	-55	-36	-176.5	-176	65.3	0	0	0	113.8	F393 L395 T445 H448 A449 P457	F393-L455 HydrophobicContact CE1-CD1 3.86Å; L395-L455 HydrophobicContact CD1-CD1 4.34Å; T445-L455 HydrophobicContact CG2-CD1 4.1Å; T445-L455 HydrophobicContact CG2-CD2 3.88Å; H448-L455 HydrophobicContact CB-CB 4.43Å; H448-L455 HydrophobicContact CB-CD1 4.36Å; A449-L455 HydrophobicContact CB-CB 4.42Å; A449-L455 HydrophobicContact CB-CD2 3.8Å; L455-P457 WeakPolarHBondContact O-CD 3.05Å
456	F	85.6	Confident	81.6	Confident	29 Å²	29	52.6 Å²	52.6	13%	0.127	27%	0.273	C	S	.	.	S	Bend	trans	-120	81.6	179.1	-62.3	-71.5	0	0	0	109.9	F139 R142 F143 L395 D454	F139-F456 HydrophobicContact CE2-CB 4.31Å; F139-F456 AromaticContact CE2-CD2 3.61Å; F139-F456 HydrophobicContact CE2-CD2 3.61Å; F139-F456 HydrophobicContact CE2-CE2 4.12Å; F139-F456 HydrophobicContact CE2-CG 4.03Å; F139-F456 HydrophobicContact CZ-CD2 4.27Å; F139-F456 HydrophobicContact CZ-CE2 4.34Å; R142-F456 HydrophobicContact CB-CB 4.23Å; R142-F456 WeakPolarHBondContact CD-O 3.45Å; R142-F456 PolarHBondContact NH1-O 3.39Å; F143-F456 HydrophobicContact CD2-CD1 4.02Å; F143-F456 AromaticContact CD2-CE1 3.52Å; F143-F456 HydrophobicContact CD2-CE1 3.52Å; F143-F456 HydrophobicContact CD2-CE2 4.21Å; F143-F456 AromaticContact CD2-CZ 3.63Å; F143-F456 HydrophobicContact CD2-CZ 3.63Å; F143-F456 AromaticContact CE2-CE1 3.76Å; F143-F456 HydrophobicContact CE2-CE1 3.76Å; F143-F456 HydrophobicContact CE2-CE2 4.28Å; F143-F456 AromaticContact CE2-CZ 3.52Å; F143-F456 HydrophobicContact CE2-CZ 3.52Å; F143-F456 HydrophobicContact CG-CE1 4.49Å; L395-F456 HydrophobicContact CD2-CE1 4.07Å; D454-F456 PolarHBondContact O-N 3Å; D454-F456 VanDerWaalsContact O-N 3.15Å
457	P	83.6	Confident	80.1	Confident	89 Å²	89	52.9 Å²	52.9	58%	0.578	27%	0.27	S	S	*	.			trans	-69.3	174.7	174.8	31.5	-34.2	0	0	0	110.9	R142 D454 L455 D459	R142-P457 WeakPolarHBondContact CB-O 3.18Å; R142-P457 WeakPolarHBondContact CG-O 3.45Å; D454-P457 WeakPolarHBondContact O-CD 3.22Å; L455-P457 WeakPolarHBondContact O-CD 3.05Å; P457-D459 PolarHBondContact O-N 2.95Å
458	N	83.6	Confident	78.6	Confident	37 Å²	37	51.4 Å²	51.4	20%	0.198	26%	0.262	C	S	.	.			trans	-59.6	123.5	173.3	-75.4	-13.7	0	0	0	110.2	K135 W137 R142 V460	K135-N458 PolarHBondContact O-ND2 3.36Å; W137-N458 HydrophobicContact CD2-CB 4.06Å; W137-N458 HydrophobicContact CE3-CB 4.29Å; W137-N458 HydrophobicContact CG-CB 4.44Å; W137-N458 HydrophobicContact CZ2-CB 4.31Å; W137-N458 PolarHBondContact N-OD1 2.87Å; R142-N458 WeakPolarHBondContact CD-OD1 3.36Å; N458-V460 VanDerWaalsContact C-N 3.29Å; N458-V460 PolarHBondContact O-N 3.13Å
459	D	83.4	Confident	77.2	Confident	13 Å²	13	52.1 Å²	52.1	7%	0.07	27%	0.269	C	S	.	.			trans	-80.2	74.3	-176.6	-174.9	11.3	0	0	0	111.2	W137 L141 R218 P457 V461 I462	W137-D459 VanDerWaalsContact CZ3-O 3.28Å; W137-D459 WeakPolarHBondContact CZ3-O 3.36Å; L141-D459 WeakPolarHBondContact O-CB 3.46Å; R218-D459 IonicContact CZ-OD1 3.27Å; R218-D459 IonicContact CZ-OD2 2.97Å; R218-D459 IonicContact NH1-OD1 3.95Å; R218-D459 PolarHBondContact NH1-OD1 3.23Å; R218-D459 IonicContact NH1-OD2 2.78Å; R218-D459 PolarHBondContact NH1-OD2 3.16Å; R218-D459 IonicContact NH2-OD1 2.74Å; R218-D459 PolarHBondContact NH2-OD1 3.39Å; R218-D459 IonicContact NH2-OD2 2.74Å; P457-D459 PolarHBondContact O-N 2.95Å; D459-V461 PolarHBondContact O-N 3.46Å; D459-I462 HydrophobicContact CB-CD1 4.26Å; D459-I462 VanDerWaalsContact O-CG1 3.31Å; D459-I462 WeakPolarHBondContact O-CG1 3.24Å; D459-I462 PolarHBondContact O-N 3.46Å; D459-I462 VanDerWaalsContact O-N 3.12Å; D459-I462 WeakPolarHBondContact OD2-CG2 3.23Å
460	V	79.8	Confident	75.6	Confident	32 Å²	32	59 Å²	59	19%	0.194	29%	0.292	C	S	.	.	G	3₁₀ helix	trans	-53.9	-26	-173.7	-64.1	0	0	0	0	114.2	E121 I129 N458 I462 A463	E121-V460 WeakPolarHBondContact O-CG2 3.44Å; I129-V460 HydrophobicContact CD1-CB 3.71Å; I129-V460 HydrophobicContact CD1-CG1 3.48Å; I129-V460 VanDerWaalsContact CD1-CG1 3.48Å; N458-V460 VanDerWaalsContact C-N 3.29Å; N458-V460 PolarHBondContact O-N 3.13Å; V460-I462 VanDerWaalsContact C-N 3.25Å; V460-I462 PolarHBondContact O-N 3.32Å; V460-A463 PolarHBondContact O-N 3.39Å
461	V	77.2	Confident	73.9	Confident	2 Å²	2	57.8 Å²	57.8	1%	0.012	29%	0.289	C	S	.	.	G	3₁₀ helix	trans	-59.1	-34.2	-179.6	179.7	0	0	0	0	112.5	Y111 L115 L120 E121 H215 D459 A463	Y111-V461 HydrophobicContact CE1-CG1 4.37Å; L115-V461 HydrophobicContact CD1-CG1 4.14Å; L115-V461 HydrophobicContact CD1-CG2 4.33Å; L115-V461 HydrophobicContact CD2-CG2 4.12Å; L120-V461 WeakPolarHBondContact O-CG2 3.35Å; E121-V461 HydrophobicContact CB-CG2 4.3Å; E121-V461 HydrophobicContact CG-CG2 4.3Å; H215-V461 WeakPolarHBondContact CD2-CG1 3.35Å; D459-V461 PolarHBondContact O-N 3.46Å; V461-A463 VanDerWaalsContact C-N 3.29Å; V461-A463 PolarHBondContact O-N 3.11Å
462	I	75.4	Confident	72.1	Confident	1 Å²	1	56.2 Å²	56.2	1%	0.005	27%	0.273	C	S	.	.	G	3₁₀ helix	trans	-79.6	-11.6	179.5	76.4	-163.9	0	0	0	112.6	F73 W137 L141 A208 R211 E212 D459 V460	F73-I462 WeakPolarHBondContact CZ-O 3.4Å; W137-I462 HydrophobicContact CE3-CD1 4.39Å; W137-I462 HydrophobicContact CZ3-CD1 4.06Å; W137-I462 HydrophobicContact CZ3-CG1 4.02Å; L141-I462 HydrophobicContact CB-CD1 4.12Å; L141-I462 HydrophobicContact CD2-CD1 3.99Å; L141-I462 VanDerWaalsContact O-CD1 3.25Å; L141-I462 WeakPolarHBondContact O-CD1 3.48Å; A208-I462 HydrophobicContact CB-CD1 4.21Å; R211-I462 WeakPolarHBondContact CD-O 3.47Å; R211-I462 PolarHBondContact NH1-O 2.72Å; E212-I462 HydrophobicContact CG-CG2 4.02Å; D459-I462 HydrophobicContact CB-CD1 4.26Å; D459-I462 VanDerWaalsContact O-CG1 3.31Å; D459-I462 WeakPolarHBondContact O-CG1 3.24Å; D459-I462 PolarHBondContact O-N 3.46Å; D459-I462 VanDerWaalsContact O-N 3.12Å; D459-I462 WeakPolarHBondContact OD2-CG2 3.23Å; V460-I462 VanDerWaalsContact C-N 3.25Å; V460-I462 PolarHBondContact O-N 3.32Å
463	A	75.2	Confident	70.4	Confident	0 Å²	0	57.8 Å²	57.8	0%	0	27%	0.274	C	S	.	.	G	3₁₀ helix	trans	-113.2	14.6	-170.3	0	0	0	0	0	113.9	I129 V130 L131 W137 V460 V461	I129-A463 HydrophobicContact CG2-CB 3.35Å; I129-A463 WeakPolarHBondContact CG2-O 3.36Å; V130-A463 WeakPolarHBondContact CG2-O 3.45Å; V130-A463 PolarHBondContact N-O 3.38Å; L131-A463 HydrophobicContact CB-CB 4.03Å; L131-A463 HydrophobicContact CD1-CB 3.93Å; L131-A463 HydrophobicContact CG-CB 3.99Å; W137-A463 HydrophobicContact CH2-CB 3.42Å; W137-A463 VanDerWaalsContact CH2-CB 3.42Å; W137-A463 HydrophobicContact CZ2-CB 4.19Å; W137-A463 HydrophobicContact CZ3-CB 4.06Å; V460-A463 PolarHBondContact O-N 3.39Å; V461-A463 VanDerWaalsContact C-N 3.29Å; V461-A463 PolarHBondContact O-N 3.11Å
464	I	72.9	Confident	68.5	Low	1 Å²	1	55.7 Å²	55.7	1%	0.005	27%	0.267	C	S	.	.	B	Isolated β-bridge	trans	-66.2	139.4	175.1	-59.4	165.7	0	0	0	110.1	L106 Y111 A114 L115 L123 R211	L106-I464 HydrophobicContact CD2-CG2 4.41Å; Y111-I464 HydrophobicContact CD1-CD1 3.9Å; Y111-I464 HydrophobicContact CE1-CD1 4.18Å; A114-I464 HydrophobicContact CB-CD1 4.27Å; A114-I464 HydrophobicContact CB-CG2 3.76Å; L115-I464 HydrophobicContact CD1-CD1 3.28Å; L115-I464 HydrophobicContact CD2-CD1 3.85Å; L115-I464 HydrophobicContact CG-CD1 3.51Å; L123-I464 HydrophobicContact CD1-CG1 4.23Å; R211-I464 PolarHBondContact NH1-O 3.45Å
465	S	66.6	Low	66.5	Low	15 Å²	15	57.9 Å²	57.9	11%	0.105	27%	0.273	C	S	.	.			trans	-82	144.6	175.2	58.7	0	0	0	0	111.8	R110 K128 E467	R110-S465 PolarHBondContact NE-O 3.01Å; R110-S465 PolarHBondContact NH2-O 3.49Å; K128-S465 PolarHBondContact O-OG 2.62Å; S465-E467 VanDerWaalsContact C-N 3.3Å; S465-E467 PolarHBondContact O-N 3.39Å; S465-E467 PolarHBondContact OG-O 3.17Å
466	A	62.8	Low	64.9	Low	24 Å²	24	62.9 Å²	62.9	20%	0.198	29%	0.294	C	S	.	.	S	Bend	trans	-66.3	-33.3	175.2	0	0	0	0	0	112	E104 L106	E104-A466 HydrophobicContact CB-CB 4.07Å; L106-A466 HydrophobicContact CD2-CB 4.34Å
467	E	59.3	Low	63.1	Low	77 Å²	77	67 Å²	67	36%	0.36	31%	0.313	S	S	.	.	S	Bend	trans	-72.8	131.2	179	-69.4	-139.7	116.2	0	0	112.8	R110 S465 R473	R110-E467 PolarHBondContact NH2-O 3.22Å; S465-E467 VanDerWaalsContact C-N 3.3Å; S465-E467 PolarHBondContact O-N 3.39Å; S465-E467 PolarHBondContact OG-O 3.17Å; E467-R473 IonicContact OE1-CZ 2.95Å; E467-R473 IonicContact OE1-NH1 3.16Å; E467-R473 PolarHBondContact OE1-NH1 3.42Å; E467-R473 IonicContact OE1-NH2 3.73Å; E467-R473 PolarHBondContact OE1-NH2 3.45Å
468	Q	58.7	Low	61.3	Low	39 Å²	39	65.8 Å²	65.8	18%	0.182	30%	0.302	C	S	.	.	P	Polyproline II helix	trans	-73.5	144.3	168.1	-67	-169.3	-19.5	0	0	110.1	D113 K470	D113-Q468 PolarHBondContact OD2-NE2 3.46Å; Q468-K470 PolarHBondContact O-N 2.77Å
469	P	57.8	Low	59.7	Low	37 Å²	37	68.1 Å²	68.1	24%	0.24	32%	0.317	C	S	.	.	P	Polyproline II helix	trans	-55.7	132.6	177	19	-29.8	0	0	0	110.7	E127 Q471 K472	E127-P469 WeakPolarHBondContact OE1-CD 3.41Å; E127-P469 WeakPolarHBondContact OE2-CD 3.27Å; P469-Q471 PolarHBondContact O-N 3.22Å; P469-K472 PolarHBondContact O-N 2.84Å
470	K	54.5	Low	57.6	Low	176 Å²	176	75.7 Å²	75.7	77%	0.765	35%	0.35	S	S	*	.	H	α-helix	trans	-46.7	-33.2	-172.3	-70.2	-175.2	179.1	-179.1	0	113.8	Q468 K472 R473 W474	Q468-K470 PolarHBondContact O-N 2.77Å; K470-K472 VanDerWaalsContact C-N 3.33Å; K470-K472 PolarHBondContact O-N 3.46Å; K470-R473 PolarHBondContact O-N 3.42Å; K470-W474 PolarHBondContact O-N 3.1Å
471	Q	54.3	Low	56	Low	128 Å²	128	79.3 Å²	79.3	60%	0.598	37%	0.365	S	S	*	.	H	α-helix	trans	-57.6	-40.1	178.3	-152.6	175.1	11.4	0	0	112.8	P469 W474 F475	P469-Q471 PolarHBondContact O-N 3.22Å; Q471-W474 PolarHBondContact O-N 3.32Å; Q471-F475 HydrophobicContact CG-CD2 4.48Å; Q471-F475 HydrophobicContact CG-CE2 4.3Å; Q471-F475 VanDerWaalsContact O-CD2 3.28Å; Q471-F475 WeakPolarHBondContact O-CD2 3.3Å; Q471-F475 PolarHBondContact O-N 2.6Å; Q471-F475 VanDerWaalsContact O-N 3.17Å
472	K	50.8	Low	54.3	Low	79 Å²	79	83.5 Å²	83.5	34%	0.343	39%	0.394	S	S	.	.	H	α-helix	trans	-72	-34.8	177.2	-95.1	-173.4	175.1	-178.8	0	113.1	P469 K470 W474 F475 K476	P469-K472 PolarHBondContact O-N 2.84Å; K470-K472 VanDerWaalsContact C-N 3.33Å; K470-K472 PolarHBondContact O-N 3.46Å; K472-W474 VanDerWaalsContact C-N 3.29Å; K472-W474 PolarHBondContact O-N 2.91Å; K472-F475 PolarHBondContact O-N 3.47Å; K472-K476 PolarHBondContact O-N 3.33Å
473	R	47.1	Very low	52.7	Low	130 Å²	130	92.7 Å²	92.7	49%	0.491	43%	0.43	S	S	.	.	H	α-helix	trans	-60.1	-43.5	174.5	-76.8	-173.1	176.5	159.2	5.1	110	E467 K470 K476 H477	E467-R473 IonicContact OE1-CZ 2.95Å; E467-R473 IonicContact OE1-NH1 3.16Å; E467-R473 PolarHBondContact OE1-NH1 3.42Å; E467-R473 IonicContact OE1-NH2 3.73Å; E467-R473 PolarHBondContact OE1-NH2 3.45Å; K470-R473 PolarHBondContact O-N 3.42Å; R473-K476 PolarHBondContact O-N 2.98Å; R473-H477 WeakPolarHBondContact O-CB 3.23Å; R473-H477 PolarHBondContact O-N 3.47Å
474	W	42.6	Very low	50.8	Low	166 Å²	166	95.4 Å²	95.4	63%	0.629	46%	0.458	S	S	*	.	H	α-helix	trans	-63.3	-46.7	176.8	-168.5	71.5	0	0	0	112.4	K470 Q471 K472 K476 H477 L478	K470-W474 PolarHBondContact O-N 3.1Å; Q471-W474 PolarHBondContact O-N 3.32Å; K472-W474 VanDerWaalsContact C-N 3.29Å; K472-W474 PolarHBondContact O-N 2.91Å; W474-K476 PolarHBondContact O-N 3.32Å; W474-H477 PolarHBondContact O-N 3.34Å; W474-L478 HydrophobicContact CD2-CD1 3.63Å; W474-L478 HydrophobicContact CD2-CG 4.29Å; W474-L478 HydrophobicContact CE3-CD1 3.45Å; W474-L478 VanDerWaalsContact CE3-CD1 3.45Å; W474-L478 HydrophobicContact CH2-CD1 3.48Å; W474-L478 VanDerWaalsContact CH2-CD1 3.48Å; W474-L478 HydrophobicContact CZ2-CD1 3.63Å; W474-L478 HydrophobicContact CZ2-CD2 4.45Å; W474-L478 HydrophobicContact CZ2-CG 4.4Å; W474-L478 HydrophobicContact CZ3-CD1 3.38Å; W474-L478 WeakPolarHBondContact O-CG 3.45Å; W474-L478 PolarHBondContact O-N 3.48Å
475	F	42.9	Very low	49	Very low	117 Å²	117	102.3 Å²	102.3	51%	0.513	49%	0.494	S	S	.	.	H	α-helix	trans	-60.5	-43.8	176.3	-88	-74.1	0	0	0	113.3	Q471 K472 H477 L478 T479	Q471-F475 HydrophobicContact CG-CD2 4.48Å; Q471-F475 HydrophobicContact CG-CE2 4.3Å; Q471-F475 VanDerWaalsContact O-CD2 3.28Å; Q471-F475 WeakPolarHBondContact O-CD2 3.3Å; Q471-F475 PolarHBondContact O-N 2.6Å; Q471-F475 VanDerWaalsContact O-N 3.17Å; K472-F475 PolarHBondContact O-N 3.47Å; F475-H477 VanDerWaalsContact C-N 3.32Å; F475-H477 PolarHBondContact O-N 3.39Å; F475-L478 PolarHBondContact O-N 2.88Å; F475-T479 PolarHBondContact O-N 3.31Å; F475-T479 PolarHBondContact O-OG1 2.95Å
476	K	49.8	Very low	47.3	Very low	129 Å²	129	108.6 Å²	108.6	56%	0.561	53%	0.527	S	S	*	.	H	α-helix	trans	-64.6	-36.2	175.5	-83.4	-174.5	177.1	175.8	0	112.3	K472 R473 W474 T479 K480	K472-K476 PolarHBondContact O-N 3.33Å; R473-K476 PolarHBondContact O-N 2.98Å; W474-K476 PolarHBondContact O-N 3.32Å; K476-T479 WeakPolarHBondContact CA-OG1 3.27Å; K476-T479 PolarHBondContact O-N 3.04Å; K476-K480 WeakPolarHBondContact O-CB 3.25Å; K476-K480 PolarHBondContact O-N 3.13Å
477	H	46.5	Very low	45.7	Very low	114 Å²	114	116.8 Å²	116.8	53%	0.528	56%	0.561	S	S	.	*	H	α-helix	trans	-65.3	-44.7	176.4	-150.2	-82.6	0	0	0	111	R473 W474 F475 T479 K480 E481	R473-H477 WeakPolarHBondContact O-CB 3.23Å; R473-H477 PolarHBondContact O-N 3.47Å; W474-H477 PolarHBondContact O-N 3.34Å; F475-H477 VanDerWaalsContact C-N 3.32Å; F475-H477 PolarHBondContact O-N 3.39Å; H477-T479 PolarHBondContact O-N 2.94Å; H477-K480 PolarHBondContact O-N 2.94Å; H477-E481 IonicContact CE1-OE1 3.5Å; H477-E481 PolarHBondContact CE1-OE1 3.06Å; H477-E481 IonicContact ND1-OE1 4Å; H477-E481 PolarHBondContact ND1-OE1 3.14Å; H477-E481 IonicContact ND1-OE2 3.15Å; H477-E481 PolarHBondContact O-N 3.41Å
478	L	45.6	Very low	44.2	Very low	64 Å²	64	124.5 Å²	124.5	34%	0.335	59%	0.587	S	S	.	*	H	α-helix	trans	-63.3	-39.5	175.6	-72.6	171.4	0	0	0	113.1	W474 F475 K480 E481 S482	W474-L478 HydrophobicContact CD2-CD1 3.63Å; W474-L478 HydrophobicContact CD2-CG 4.29Å; W474-L478 HydrophobicContact CE3-CD1 3.45Å; W474-L478 VanDerWaalsContact CE3-CD1 3.45Å; W474-L478 HydrophobicContact CH2-CD1 3.48Å; W474-L478 VanDerWaalsContact CH2-CD1 3.48Å; W474-L478 HydrophobicContact CZ2-CD1 3.63Å; W474-L478 HydrophobicContact CZ2-CD2 4.45Å; W474-L478 HydrophobicContact CZ2-CG 4.4Å; W474-L478 HydrophobicContact CZ3-CD1 3.38Å; W474-L478 WeakPolarHBondContact O-CG 3.45Å; W474-L478 PolarHBondContact O-N 3.48Å; F475-L478 PolarHBondContact O-N 2.88Å; L478-K480 VanDerWaalsContact C-N 3.3Å; L478-K480 PolarHBondContact O-N 3.31Å; L478-E481 PolarHBondContact O-N 3.27Å; L478-S482 VanDerWaalsContact O-CB 3.24Å; L478-S482 WeakPolarHBondContact O-CB 3.16Å; L478-S482 PolarHBondContact O-N 3.16Å
479	T	49.7	Very low	42.5	Very low	86 Å²	86	128.5 Å²	128.5	53%	0.528	62%	0.618	S	S	.	*	H	α-helix	trans	-67.8	-34.1	176.5	3.1	0	0	0	0	111.6	F475 K476 H477 Y483	F475-T479 PolarHBondContact O-N 3.31Å; F475-T479 PolarHBondContact O-OG1 2.95Å; K476-T479 WeakPolarHBondContact CA-OG1 3.27Å; K476-T479 PolarHBondContact O-N 3.04Å; H477-T479 PolarHBondContact O-N 2.94Å; T479-Y483 PolarHBondContact O-N 3.07Å
480	K	40.4	Very low	41	Very low	173 Å²	173	132.1 Å²	132.1	75%	0.752	64%	0.641	S	S	*	*	H	α-helix	trans	-71.1	-40.9	175.1	-117.3	-178.1	174.9	-172.7	0	112.6	K476 H477 L478 G484	K476-K480 WeakPolarHBondContact O-CB 3.25Å; K476-K480 PolarHBondContact O-N 3.13Å; H477-K480 PolarHBondContact O-N 2.94Å; L478-K480 VanDerWaalsContact C-N 3.3Å; L478-K480 PolarHBondContact O-N 3.31Å; K480-G484 PolarHBondContact O-N 3.39Å
481	E	46.9	Very low	39.6	Very low	108 Å²	108	133.2 Å²	133.2	51%	0.505	65%	0.646	S	S	.	*	H	α-helix	trans	-69.1	-36.7	176.4	-80.4	175.3	169.8	0	0	112.1	H477 L478 Y483 G484	H477-E481 IonicContact CE1-OE1 3.5Å; H477-E481 PolarHBondContact CE1-OE1 3.06Å; H477-E481 IonicContact ND1-OE1 4Å; H477-E481 PolarHBondContact ND1-OE1 3.14Å; H477-E481 IonicContact ND1-OE2 3.15Å; H477-E481 PolarHBondContact O-N 3.41Å; L478-E481 PolarHBondContact O-N 3.27Å; E481-Y483 VanDerWaalsContact C-N 3.31Å; E481-Y483 PolarHBondContact O-N 2.9Å; E481-G484 PolarHBondContact O-N 3.41Å; E481-G484 VanDerWaalsContact O-N 3.07Å
482	S	41.3	Very low	38.3	Very low	89 Å²	89	134.9 Å²	134.9	62%	0.622	66%	0.658	S	S	*	*	H	α-helix	trans	-64.7	-34.5	177.5	-168.3	0	0	0	0	112.5	L478	L478-S482 VanDerWaalsContact O-CB 3.24Å; L478-S482 WeakPolarHBondContact O-CB 3.16Å; L478-S482 PolarHBondContact O-N 3.16Å
483	Y	40.7	Very low	37	Very low	195 Å²	195	137.5 Å²	137.5	77%	0.765	67%	0.674	S	S	*	*	H	α-helix	trans	-79.1	-17.3	172.7	-96.2	-87.5	0	0	0	114	T479 E481	T479-Y483 PolarHBondContact O-N 3.07Å; E481-Y483 VanDerWaalsContact C-N 3.31Å; E481-Y483 PolarHBondContact O-N 2.9Å
484	G	36.2	Very low	36.3	Very low	57 Å²	57	137.9 Å²	137.9	59%	0.588	69%	0.686	S	S	*	*	H	α-helix	trans	-85.2	-9.8	-177.1	0	0	0	0	0	115.4	K480 E481	K480-G484 PolarHBondContact O-N 3.39Å; E481-G484 PolarHBondContact O-N 3.41Å; E481-G484 VanDerWaalsContact O-N 3.07Å
485	N	34.2	Very low	36.3	Very low	145 Å²	145	135 Å²	135	78%	0.775	69%	0.689	S	S	*	*	S	Bend	trans	-122	12.4	-166.5	-112.1	0.9	0	0	0	116.3
486	N	30.4	Very low	35.5	Very low	148 Å²	148	138 Å²	138	79%	0.791	70%	0.704	S	S	*	*			trans	-108.6	26	179.2	-100.9	7.3	0	0	0	115	R488	N486-R488 PolarHBondContact O-N 2.97Å; N486-R488 VanDerWaalsContact O-N 3.1Å
487	E	29.5	Very low	34.3	Very low	196 Å²	196	138 Å²	138	92%	0.916	71%	0.711	S	S	*	*			trans	-80.3	72.1	159.3	-77.2	-170.4	164	0	0	110.4
488	R	27.5	Very low	33.3	Very low	238 Å²	238	138.8 Å²	138.8	90%	0.898	72%	0.719	S	S	*	*			trans	-160.5	73.3	160	-114.2	175.2	-168.2	-173.8	3.5	109.1	N486 P490	N486-R488 PolarHBondContact O-N 2.97Å; N486-R488 VanDerWaalsContact O-N 3.1Å; R488-P490 VanDerWaalsContact O-CD 3.25Å; R488-P490 WeakPolarHBondContact O-CD 3.41Å
489	C	24.4	Very low	32.4	Very low	124 Å²	124	143.7 Å²	143.7	84%	0.838	74%	0.74	S	S	*	*			trans	-73	116.4	166	-74.3	0	0	0	0	109.7
490	P	26.9	Very low	31.1	Very low	112 Å²	112	147.1 Å²	147.1	73%	0.727	75%	0.754	S	S	*	*			trans	-79.3	122.3	158.1	5.2	15.3	0	0	0	107.6	R488 I492	R488-P490 VanDerWaalsContact O-CD 3.25Å; R488-P490 WeakPolarHBondContact O-CD 3.41Å; P490-I492 PolarHBondContact O-N 3.29Å
491	K	23.1	Very low	30.5	Very low	199 Å²	199	146 Å²	146	87%	0.865	76%	0.756	S	S	*	*			trans	-57.8	113.3	171.5	-65.5	173.5	176.4	-179.8	0	109.2
492	I	28.3	Very low	29.6	Very low	164 Å²	164	148.6 Å²	148.6	84%	0.841	77%	0.772	S	S	*	*			trans	-112.1	118	161.3	-65.8	176.2	0	0	0	105.7	P490	P490-I492 PolarHBondContact O-N 3.29Å
493	L	23.1	Very low	28.9	Very low	133 Å²	133	153.7 Å²	153.7	70%	0.696	79%	0.786	S	S	*	*			trans	-69.8	139.4	178.7	-86.6	85.4	0	0	0	111
494	D	31.8	Very low	28.1	Very low	138 Å²	138	149.4 Å²	149.4	74%	0.738	79%	0.785	S	S	*	*			trans	63.6	161.2	134.6	-64.4	-9.4	0	0	0	120.6
495	P	43.4	Very low	27.8	Very low	106 Å²	106	152.3 Å²	152.3	69%	0.688	79%	0.793	S	S	*	*			cis	-139.9	-173.7	-28.8	33.5	-12.2	0	0	0	113.5
496	E	26.6	Very low	27.7	Very low	179 Å²	179	151.1 Å²	151.1	84%	0.836	79%	0.794	S	S	*	*			trans	78.2	94.8	161.4	-56.6	-170.1	166.1	0	0	116.8
497	D	24.2	Very low	27.7	Very low	131 Å²	131	151.9 Å²	151.9	70%	0.701	80%	0.797	S	S	*	*				73.3	102.9	78.2	-164.4	35.9	0	0	0	112.8
498	N	24.8	Very low	27.6	Very low	130 Å²	130	149.5 Å²	149.5	70%	0.695	80%	0.795	S	S	*	*				172	142.9	113.7	-94.8	-65.6	0	0	0	113.7
499	Q	26.2	Very low	27.6	Very low	167 Å²	167	144.9 Å²	144.9	78%	0.78	79%	0.788	S	S	*	*			trans	81.9	80.3	158.7	-74.2	175.8	-8.9	0	0	119
500	I	23.6	Very low	27.7	Very low	157 Å²	157	144.3 Å²	144.3	81%	0.805	78%	0.781	S	S	*	*			trans	-105.6	110	145	-62.4	168.9	0	0	0	106.4
501	D	26.6	Very low	27.9	Very low	151 Å²	151	146.9 Å²	146.9	81%	0.807	79%	0.789	S	S	*	*			trans	-123.9	84.7	163.3	-74.1	-39.7	0	0	0	107.9
502	L	29.4	Very low	28.1	Very low	161 Å²	161	142.5 Å²	142.5	84%	0.843	78%	0.783	S	S	*	*			trans	-100.5	98.4	166.3	-146.1	95.3	0	0	0	108	S504	L502-S504 PolarHBondContact O-N 3.45Å
503	E	25.7	Very low	28.2	Very low	197 Å²	197	140 Å²	140	92%	0.921	78%	0.78	S	S	*	*			trans	-57.6	109.1	179.4	-149.1	166.5	-179.1	0	0	110.4
504	S	25.3	Very low	28.7	Very low	104 Å²	104	140 Å²	140	73%	0.727	79%	0.786	S	S	*	*			trans	-120.1	121.8	165.5	40.8	0	0	0	0	108.1	L502	L502-S504 PolarHBondContact O-N 3.45Å
505	P	29.5	Very low	28.8	Very low	119 Å²	119	139.5 Å²	139.5	77%	0.773	79%	0.787	S	S	*	*			trans	-74.7	152.7	-172.9	28.8	-31.8	0	0	0	111.5
506	P	31.8	Very low	28.4	Very low	120 Å²	120	143 Å²	143	78%	0.779	79%	0.794	S	S	*	*			trans	-81.8	132.8	-151.1	30.9	-33.8	0	0	0	112.5	V508	P506-V508 PolarHBondContact O-N 3.09Å
507	L	29.7	Very low	28.6	Very low	164 Å²	164	141.3 Å²	141.3	86%	0.859	79%	0.791	S	S	*	*			trans	-72.9	110.5	162.7	-80.4	164.1	0	0	0	108.6	N509	L507-N509 PolarHBondContact O-N 3.24Å; L507-N509 VanDerWaalsContact O-N 3.11Å
508	V	27.5	Very low	28.9	Very low	145 Å²	145	140.3 Å²	140.3	88%	0.879	79%	0.794	S	S	*	*			trans	-55.9	110.9	168.5	175.8	0	0	0	0	108.4	P506	P506-V508 PolarHBondContact O-N 3.09Å
509	N	27.3	Very low	29.5	Very low	141 Å²	141	145.4 Å²	145.4	75%	0.754	82%	0.822	S	S	*	*			trans	-142.1	155.9	170.8	-110.5	-16.7	0	0	0	108	L507	L507-N509 PolarHBondContact O-N 3.24Å; L507-N509 VanDerWaalsContact O-N 3.11Å
510	V	26.9	Very low	29.7	Very low	113 Å²	113	144.4 Å²	144.4	69%	0.685	82%	0.824	S	S	*	*			trans	89.3	113	167.9	-160.3	0	0	0	0	113.8
511	D	30.5	Very low	30	Very low	166 Å²	166	143.7 Å²	143.7	89%	0.888	83%	0.825	S	S	*	*				-161.6	97	112.7	-90.5	-21.8	0	0	0	110.2
512	S	27.4	Very low	30.2	Very low	107 Å²	107	143.3 Å²	143.3	75%	0.748	83%	0.826	S	S	*	*			trans	-137.7	85.7	165.1	61	0	0	0	0	108.2
513	S	30.2	Very low	30.3	Very low	112 Å²	112	142.2 Å²	142.2	78%	0.783	83%	0.825	S	S	*	*			trans	169.5	96.4	145.2	53.3	0	0	0	0	111
514	T	33.8	Very low	30.5	Very low	132 Å²	132	138.8 Å²	138.8	81%	0.81	82%	0.819	S	S	*	*			trans	-118	82.4	156.1	-43.5	0	0	0	0	107.4
515	V	34.3	Very low	30.9	Very low	127 Å²	127	141.1 Å²	141.1	77%	0.77	83%	0.825	S	S	*	*			trans	-98.2	94.7	159.8	175.2	0	0	0	0	105.2
516	Q	35.5	Very low	31	Very low	180 Å²	180	142.7 Å²	142.7	84%	0.841	83%	0.829	S	S	*	*			trans	-104.8	104	164.2	-102.6	-177.8	-29.8	0	0	107.8
517	N	29.8	Very low	30.9	Very low	144 Å²	144	144.5 Å²	144.5	77%	0.77	83%	0.832	S	S	*	*			trans	-84.4	158.4	160.7	-92.1	-22.9	0	0	0	109.6
518	S	30.4	Very low	31	Very low	109 Å²	109	142.8 Å²	142.8	76%	0.762	83%	0.83	S	S	*	*			trans	90.2	112.3	159.6	81	0	0	0	0	118.7
519	N	39	Very low	31.4	Very low	238 Å²	238	142.6 Å²	142.6	100%	1.273	83%	0.826	S	S	*	*			trans	77.7	0	159	-63.9	-8	0	0	0	119.1

Retrieved 519 of 519 residues in 2239.6 ms (Link to these results)

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