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ER membrane protein complex subunit 6

Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins^1,2,3,4,5. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues^6,7,8. Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices^9,10. It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes^11,12. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors¹³. By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes (Probable).

AlphaFold DB , UniProt , Accession Q9BV81, Species HUMAN (Homo sapiens, Human), Gene EMC6, Length 110 aa.

						>EMC6_HUMAN|Q9BV81|EMC6
MAAVVAKREGPPFISEAAVRGNAAVLDYCRTSVSALSGATAGILGLTGLYGFIFYLLASVLLSLLLILKAGRRWNKYFKSRRPLFTGGLIGGLFTYVLFWTFLYGMVHVY
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	40.6	Very low	53.4	Low	251 Å²	251	136.5 Å²	136.5	100%	1.236	78%	0.779	S	S	*	*				0	78.6	0	-156.6	178.4	-167.4	0	0	108
2	A	52.5	Low	54	Low	96 Å²	96	134.1 Å²	134.1	79%	0.793	77%	0.772	S	S	*	*			trans	-94.4	114.4	174.8	0	0	0	0	0	106.9	V4	A2-V4 PolarHBondContact O-N 2.86Å
3	A	55.7	Low	54.5	Low	90 Å²	90	127.8 Å²	127.8	74%	0.744	73%	0.731	S	S	*	*			trans	-51	115.4	176.1	0	0	0	0	0	108.8	V5	A3-V5 VanDerWaalsContact C-N 3.29Å; A3-V5 PolarHBondContact O-N 3.04Å
4	V	59.8	Low	55.1	Low	138 Å²	138	128.8 Å²	128.8	84%	0.836	73%	0.73	S	S	*	*			trans	-55.3	105.2	162.4	172.1	0	0	0	0	104.7	A2 A6	A2-V4 PolarHBondContact O-N 2.86Å; V4-A6 PolarHBondContact O-N 2.76Å
5	V	58.5	Low	56.5	Low	130 Å²	130	124.1 Å²	124.1	79%	0.788	71%	0.709	S	S	*	*			trans	-55.7	100.5	172.3	171.4	0	0	0	0	105	A3 K7	A3-V5 VanDerWaalsContact C-N 3.29Å; A3-V5 PolarHBondContact O-N 3.04Å; V5-K7 VanDerWaalsContact C-N 3.29Å; V5-K7 PolarHBondContact O-N 2.82Å
6	A	56.8	Low	57.8	Low	81 Å²	81	125.4 Å²	125.4	67%	0.669	71%	0.707	S	S	*	*			trans	-55	104.6	169.3	0	0	0	0	0	104.8	V4 R8	V4-A6 PolarHBondContact O-N 2.76Å; A6-R8 VanDerWaalsContact C-N 3.29Å; A6-R8 PolarHBondContact O-N 2.79Å
7	K	54.9	Low	59.4	Low	165 Å²	165	122.8 Å²	122.8	72%	0.717	70%	0.704	S	S	*	*			trans	-52.7	103.6	171.6	178.4	-175.1	175.1	-155.5	0	104.6	V5 E9	V5-K7 VanDerWaalsContact C-N 3.29Å; V5-K7 PolarHBondContact O-N 2.82Å; K7-E9 VanDerWaalsContact C-N 3.32Å; K7-E9 PolarHBondContact O-N 2.77Å
8	R	50	Low	60.7	Low	241 Å²	241	118.4 Å²	118.4	91%	0.909	69%	0.686	S	S	*	*			trans	-56.5	106.9	172.9	-77.2	-169.9	176.2	-158.7	-0.1	104.7	A6 G10	A6-R8 VanDerWaalsContact C-N 3.29Å; A6-R8 PolarHBondContact O-N 2.79Å; R8-G10 PolarHBondContact O-N 2.83Å
9	E	50.8	Low	61.8	Low	166 Å²	166	113.6 Å²	113.6	78%	0.776	66%	0.658	S	S	*	*			trans	-71.3	70.6	167.1	-59.2	-132.6	139.9	0	0	105.8	K7	K7-E9 VanDerWaalsContact C-N 3.32Å; K7-E9 PolarHBondContact O-N 2.77Å
10	G	52.8	Low	63	Low	44 Å²	44	117.8 Å²	117.8	45%	0.454	66%	0.663	S	S	.	*			trans	-53.6	152.8	155.6	0	0	0	0	0	107.5	R8	R8-G10 PolarHBondContact O-N 2.83Å
11	P	55.4	Low	64.2	Low	100 Å²	100	113.8 Å²	113.8	65%	0.649	65%	0.647	S	S	*	*			trans	-44.1	130.2	-174.7	15.4	-29	0	0	0	109.4	F13	P11-F13 CarbonylContact O-C 3.41Å; P11-F13 PolarHBondContact O-N 3.45Å
12	P	59.9	Low	66.4	Low	107 Å²	107	104.6 Å²	104.6	70%	0.695	60%	0.603	S	S	*	*	S	Bend	trans	-55.6	-18.3	-167.7	16.1	-29.4	0	0	0	113.3
13	F	60.9	Low	68	Low	53 Å²	53	101.9 Å²	101.9	23%	0.232	58%	0.581	C	S	.	*			trans	-115.5	113.4	171.7	-54.9	-72.5	0	0	0	110.1	P11 S15 V19 K79	P11-F13 CarbonylContact O-C 3.41Å; P11-F13 PolarHBondContact O-N 3.45Å; F13-S15 VanDerWaalsContact C-N 3.3Å; F13-S15 PolarHBondContact O-N 2.8Å; F13-V19 HydrophobicContact CB-CG2 4.45Å; F13-V19 HydrophobicContact CD1-CG2 3.83Å; F13-V19 HydrophobicContact CG-CG2 4.5Å; F13-K79 HydrophobicContact CE1-CB 3.83Å; F13-K79 HydrophobicContact CE1-CG 4.13Å; F13-K79 HydrophobicContact CE2-CD 4.11Å; F13-K79 HydrophobicContact CE2-CG 3.98Å; F13-K79 HydrophobicContact CZ-CB 3.74Å; F13-K79 HydrophobicContact CZ-CD 4.1Å; F13-K79 HydrophobicContact CZ-CG 3.52Å
14	I	62.3	Low	69.5	Low	141 Å²	141	100.4 Å²	100.4	72%	0.723	57%	0.569	S	S	*	*	S	Bend	trans	-67.9	-31.4	-179.1	-62	169.6	0	0	0	111.2
15	S	76.4	Confident	71	Confident	58 Å²	58	98.1 Å²	98.1	41%	0.406	56%	0.555	S	S	.	*			trans	-155	116.9	175.8	53.9	0	0	0	0	111.3	F13 A17 A18 V19	F13-S15 VanDerWaalsContact C-N 3.3Å; F13-S15 PolarHBondContact O-N 2.8Å; S15-A17 PolarHBondContact O-N 3.39Å; S15-A18 PolarHBondContact O-N 2.96Å; S15-A18 WeakPolarHBondContact OG-CB 3.37Å; S15-V19 PolarHBondContact O-N 2.95Å
16	E	78	Confident	72.5	Confident	145 Å²	145	92.2 Å²	92.2	68%	0.678	52%	0.519	S	S	*	.	H	α-helix	trans	-61.2	-33.9	177.6	-61.5	-167	157.9	0	0	111.9	A18 V19 R20	E16-A18 PolarHBondContact O-N 3.06Å; E16-V19 PolarHBondContact O-N 3.21Å; E16-R20 WeakPolarHBondContact O-CG 3.12Å; E16-R20 PolarHBondContact O-N 3.05Å
17	A	84.1	Confident	74	Confident	81 Å²	81	92.1 Å²	92.1	67%	0.669	51%	0.507	S	S	*	.	H	α-helix	trans	-59.4	-42.2	175.3	0	0	0	0	0	112.5	S15 R20 G21	S15-A17 PolarHBondContact O-N 3.39Å; A17-R20 PolarHBondContact O-N 3.31Å; A17-G21 PolarHBondContact O-N 3.46Å
18	A	82.4	Confident	75.8	Confident	45 Å²	45	92.2 Å²	92.2	37%	0.372	50%	0.504	S	S	.	.	H	α-helix	trans	-70.6	-37.7	179.1	0	0	0	0	0	112	S15 E16 R20 G21 N22	S15-A18 PolarHBondContact O-N 2.96Å; S15-A18 WeakPolarHBondContact OG-CB 3.37Å; E16-A18 PolarHBondContact O-N 3.06Å; A18-R20 VanDerWaalsContact C-N 3.35Å; A18-G21 PolarHBondContact O-N 3.29Å; A18-N22 PolarHBondContact O-N 3.44Å; A18-N22 PolarHBondContact O-ND2 3.05Å
19	V	82.7	Confident	77.7	Confident	27 Å²	27	82.8 Å²	82.8	16%	0.164	48%	0.475	C	S	.	.	H	α-helix	trans	-63.6	-42.7	175.5	178.8	0	0	0	0	110.7	F13 S15 E16 N22 A23 K79	F13-V19 HydrophobicContact CB-CG2 4.45Å; F13-V19 HydrophobicContact CD1-CG2 3.83Å; F13-V19 HydrophobicContact CG-CG2 4.5Å; S15-V19 PolarHBondContact O-N 2.95Å; E16-V19 PolarHBondContact O-N 3.21Å; V19-N22 PolarHBondContact O-N 3.36Å; V19-A23 PolarHBondContact O-N 2.91Å; V19-A23 VanDerWaalsContact O-N 3.11Å; V19-K79 HydrophobicContact CG1-CB 4.46Å
20	R	84.8	Confident	79.6	Confident	197 Å²	197	75.3 Å²	75.3	74%	0.743	44%	0.44	S	S	*	.	H	α-helix	trans	-64.5	-41.6	174.5	-71	178.1	70.8	173.4	1.6	112	E16 A17 A18 A23 A24	E16-R20 WeakPolarHBondContact O-CG 3.12Å; E16-R20 PolarHBondContact O-N 3.05Å; A17-R20 PolarHBondContact O-N 3.31Å; A18-R20 VanDerWaalsContact C-N 3.35Å; R20-A23 WeakPolarHBondContact O-CB 3.38Å; R20-A23 PolarHBondContact O-N 3.29Å; R20-A24 PolarHBondContact O-N 3.17Å
21	G	88.4	Confident	81.5	Confident	33 Å²	33	76.5 Å²	76.5	34%	0.34	44%	0.438	S	S	.	.	H	α-helix	trans	-59.6	-45.9	174.8	0	0	0	0	0	112.5	A17 A18 A23 A24 V25	A17-G21 PolarHBondContact O-N 3.46Å; A18-G21 PolarHBondContact O-N 3.29Å; G21-A23 VanDerWaalsContact C-N 3.3Å; G21-A23 PolarHBondContact O-N 3.14Å; G21-A24 PolarHBondContact O-N 2.99Å; G21-V25 WeakPolarHBondContact O-CG2 3.31Å; G21-V25 PolarHBondContact O-N 2.88Å
22	N	87	Confident	83.4	Confident	58 Å²	58	73.5 Å²	73.5	31%	0.31	42%	0.419	S	S	.	.	H	α-helix	trans	-61.4	-37.8	176.3	-67.4	-20.2	0	0	0	112.4	A18 V19 L26 Y77 F78	A18-N22 PolarHBondContact O-N 3.44Å; A18-N22 PolarHBondContact O-ND2 3.05Å; V19-N22 PolarHBondContact O-N 3.36Å; N22-L26 WeakPolarHBondContact O-CB 3.31Å; N22-L26 PolarHBondContact O-N 3.41Å; N22-Y77 PolarHBondContact ND2-O 3.41Å; N22-F78 HydrophobicContact CB-CE1 4.12Å; N22-F78 HydrophobicContact CB-CZ 4.07Å
23	A	85.5	Confident	85	Confident	39 Å²	39	70.6 Å²	70.6	32%	0.322	40%	0.399	S	S	.	.	H	α-helix	trans	-64.2	-45.2	175.4	0	0	0	0	0	111.6	V19 R20 G21 V25 L26 D27	V19-A23 PolarHBondContact O-N 2.91Å; V19-A23 VanDerWaalsContact O-N 3.11Å; R20-A23 WeakPolarHBondContact O-CB 3.38Å; R20-A23 PolarHBondContact O-N 3.29Å; G21-A23 VanDerWaalsContact C-N 3.3Å; G21-A23 PolarHBondContact O-N 3.14Å; A23-V25 PolarHBondContact O-N 3.21Å; A23-L26 WeakPolarHBondContact O-CB 3.28Å; A23-L26 PolarHBondContact O-N 3.41Å; A23-D27 PolarHBondContact O-N 2.98Å
24	A	89.2	Confident	86.7	Confident	60 Å²	60	68.3 Å²	68.3	50%	0.496	39%	0.39	S	S	.	.	H	α-helix	trans	-62.5	-42.2	177.2	0	0	0	0	0	112.6	R20 G21 L26 D27 Y28	R20-A24 PolarHBondContact O-N 3.17Å; G21-A24 PolarHBondContact O-N 2.99Å; A24-L26 VanDerWaalsContact C-N 3.31Å; A24-L26 PolarHBondContact O-N 2.83Å; A24-D27 PolarHBondContact O-N 3.44Å; A24-Y28 WeakPolarHBondContact O-CB 3.23Å; A24-Y28 PolarHBondContact O-N 3.44Å
25	V	90.2	Very high	88.3	Confident	89 Å²	89	62.6 Å²	62.6	54%	0.539	36%	0.364	S	S	.	.	H	α-helix	trans	-62.3	-40.4	175.2	173.4	0	0	0	0	111	G21 A23 Y28 C29	G21-V25 WeakPolarHBondContact O-CG2 3.31Å; G21-V25 PolarHBondContact O-N 2.88Å; A23-V25 PolarHBondContact O-N 3.21Å; V25-Y28 PolarHBondContact O-N 2.91Å; V25-C29 PolarHBondContact O-N 3.22Å; V25-C29 PolarHBondContact O-SG 2.89Å
26	L	89.1	Confident	89.3	Confident	6 Å²	6	65.4 Å²	65.4	3%	0.031	37%	0.374	C	S	.	.	H	α-helix	trans	-63.1	-44.2	177.1	178.2	148.9	0	0	0	111.9	N22 A23 A24 Y28 C29 R30 L66 F78 L84	N22-L26 WeakPolarHBondContact O-CB 3.31Å; N22-L26 PolarHBondContact O-N 3.41Å; A23-L26 WeakPolarHBondContact O-CB 3.28Å; A23-L26 PolarHBondContact O-N 3.41Å; A24-L26 VanDerWaalsContact C-N 3.31Å; A24-L26 PolarHBondContact O-N 2.83Å; L26-Y28 VanDerWaalsContact C-N 3.32Å; L26-Y28 PolarHBondContact O-N 2.98Å; L26-C29 PolarHBondContact O-N 3.37Å; L26-R30 VanDerWaalsContact CD2-NE 3.32Å; L26-R30 WeakPolarHBondContact O-CG 3.39Å; L26-R30 PolarHBondContact O-N 3.44Å; L26-L66 HydrophobicContact CD1-CD1 4.18Å; L26-L66 HydrophobicContact CG-CD1 4.29Å; L26-F78 HydrophobicContact CB-CE1 4.31Å; L26-F78 HydrophobicContact CB-CZ 4.3Å; L26-F78 HydrophobicContact CD1-CE1 3.77Å; L26-F78 HydrophobicContact CD1-CZ 3.68Å; L26-L84 HydrophobicContact CD1-CD2 3.68Å
27	D	89.4	Confident	90.2	Very high	80 Å²	80	59 Å²	59	43%	0.428	35%	0.345	S	S	.	.	H	α-helix	trans	-64.3	-38.4	176.9	-70.9	-28.1	0	0	0	111.8	A23 A24 R30 T31	A23-D27 PolarHBondContact O-N 2.98Å; A24-D27 PolarHBondContact O-N 3.44Å; D27-R30 PolarHBondContact O-N 2.96Å; D27-T31 PolarHBondContact O-N 3.02Å; D27-T31 PolarHBondContact O-OG1 3.22Å
28	Y	91.6	Very high	90.8	Very high	167 Å²	167	55.1 Å²	55.1	66%	0.655	31%	0.313	S	S	*	.	H	α-helix	trans	-61.8	-50.8	173.4	-177.7	-101.3	0	0	0	111.7	A24 V25 L26 R30 T31 S32	A24-Y28 WeakPolarHBondContact O-CB 3.23Å; A24-Y28 PolarHBondContact O-N 3.44Å; V25-Y28 PolarHBondContact O-N 2.91Å; L26-Y28 VanDerWaalsContact C-N 3.32Å; L26-Y28 PolarHBondContact O-N 2.98Å; Y28-R30 VanDerWaalsContact C-N 3.25Å; Y28-R30 PolarHBondContact O-N 3.33Å; Y28-T31 PolarHBondContact O-N 2.87Å; Y28-T31 VanDerWaalsContact O-N 3.16Å; Y28-S32 PolarHBondContact O-N 2.92Å; Y28-S32 PolarHBondContact O-OG 3.04Å; Y28-S32 VanDerWaalsContact O-OG 3.12Å
29	C	91.4	Very high	91.5	Very high	43 Å²	43	53.9 Å²	53.9	29%	0.291	30%	0.303	S	S	.	.	H	α-helix	trans	-55.2	-41.8	177.1	-71.5	0	0	0	0	112.1	V25 L26 V33	V25-C29 PolarHBondContact O-N 3.22Å; V25-C29 PolarHBondContact O-SG 2.89Å; L26-C29 PolarHBondContact O-N 3.37Å; C29-V33 WeakPolarHBondContact O-CB 3.39Å; C29-V33 WeakPolarHBondContact O-CG2 3.37Å; C29-V33 PolarHBondContact O-N 3.32Å
30	R	90.2	Very high	92.2	Very high	9 Å²	9	55.8 Å²	55.8	3%	0.034	31%	0.314	C	S	.	.	H	α-helix	trans	-63.6	-49.3	177.4	-72.9	-179	-176.3	-78.3	6.8	111.9	L26 D27 Y28 S32 V33 S34 L62 P83 L84 G87	L26-R30 VanDerWaalsContact CD2-NE 3.32Å; L26-R30 WeakPolarHBondContact O-CG 3.39Å; L26-R30 PolarHBondContact O-N 3.44Å; D27-R30 PolarHBondContact O-N 2.96Å; Y28-R30 VanDerWaalsContact C-N 3.25Å; Y28-R30 PolarHBondContact O-N 3.33Å; R30-S32 VanDerWaalsContact C-N 3.34Å; R30-S32 PolarHBondContact O-N 3.39Å; R30-V33 PolarHBondContact O-N 3.11Å; R30-S34 WeakPolarHBondContact O-CB 3.45Å; R30-S34 PolarHBondContact O-N 3.42Å; R30-S34 PolarHBondContact O-OG 2.92Å; R30-L62 HydrophobicContact CB-CD2 4.31Å; R30-L62 HydrophobicContact CG-CD2 3.74Å; R30-P83 PolarHBondContact NH2-O 3.44Å; R30-L84 VanDerWaalsContact NH2-C 3.31Å; R30-L84 PolarHBondContact NH2-O 3.11Å; R30-G87 WeakPolarHBondContact CD-O 3.35Å; R30-G87 PolarHBondContact NE-O 3.37Å
31	T	92.9	Very high	92.8	Very high	69 Å²	69	46.4 Å²	46.4	42%	0.423	28%	0.279	S	S	.	.	H	α-helix	trans	-61.5	-43.7	-179.5	-52.6	0	0	0	0	111.2	D27 Y28 S34 A35 T95	D27-T31 PolarHBondContact O-N 3.02Å; D27-T31 PolarHBondContact O-OG1 3.22Å; Y28-T31 PolarHBondContact O-N 2.87Å; Y28-T31 VanDerWaalsContact O-N 3.16Å; T31-S34 PolarHBondContact O-N 3.39Å; T31-A35 PolarHBondContact O-N 3.24Å; T31-T95 HydrophobicContact CG2-CG2 4.27Å
32	S	94.7	Very high	93.1	Very high	36 Å²	36	44.8 Å²	44.8	25%	0.252	26%	0.263	S	S	.	.	H	α-helix	trans	-63.7	-45.5	177.1	-58.6	0	0	0	0	112.5	Y28 R30 S34 A35 L36	Y28-S32 PolarHBondContact O-N 2.92Å; Y28-S32 PolarHBondContact O-OG 3.04Å; Y28-S32 VanDerWaalsContact O-OG 3.12Å; R30-S32 VanDerWaalsContact C-N 3.34Å; R30-S32 PolarHBondContact O-N 3.39Å; S32-S34 VanDerWaalsContact C-N 3.35Å; S32-A35 PolarHBondContact O-N 3.25Å; S32-L36 WeakPolarHBondContact O-CG 3.42Å; S32-L36 PolarHBondContact O-N 3.43Å
33	V	95	Very high	93.5	Very high	46 Å²	46	46.6 Å²	46.6	28%	0.279	27%	0.271	S	S	.	.	H	α-helix	trans	-66.8	-38.1	178.6	170.9	0	0	0	0	111	C29 R30 L36 S37 L62	C29-V33 WeakPolarHBondContact O-CB 3.39Å; C29-V33 WeakPolarHBondContact O-CG2 3.37Å; C29-V33 PolarHBondContact O-N 3.32Å; R30-V33 PolarHBondContact O-N 3.11Å; V33-L36 PolarHBondContact O-N 2.87Å; V33-S37 VanDerWaalsContact O-CB 3.25Å; V33-S37 WeakPolarHBondContact O-CB 3.42Å; V33-S37 PolarHBondContact O-N 3.25Å; V33-S37 PolarHBondContact O-OG 3.26Å; V33-L62 HydrophobicContact CB-CD2 3.98Å; V33-L62 HydrophobicContact CG1-CB 4.34Å; V33-L62 HydrophobicContact CG1-CD2 4.16Å; V33-L62 HydrophobicContact CG2-CD1 3.96Å; V33-L62 HydrophobicContact CG2-CD2 4.07Å
34	S	95.8	Very high	94	Very high	6 Å²	6	49.9 Å²	49.9	4%	0.042	28%	0.283	C	S	.	.	H	α-helix	trans	-59.4	-44.7	172.5	-77.1	0	0	0	0	112.2	R30 T31 S32 S37 G38 G92 Y96	R30-S34 WeakPolarHBondContact O-CB 3.45Å; R30-S34 PolarHBondContact O-N 3.42Å; R30-S34 PolarHBondContact O-OG 2.92Å; T31-S34 PolarHBondContact O-N 3.39Å; S32-S34 VanDerWaalsContact C-N 3.35Å; S34-S37 PolarHBondContact O-OG 2.97Å; S34-G38 PolarHBondContact O-N 3.05Å; S34-G92 WeakPolarHBondContact CB-O 3.32Å; S34-G92 WeakPolarHBondContact OG-CA 3.3Å; S34-G92 PolarHBondContact OG-O 3.45Å; S34-Y96 WeakPolarHBondContact O-CA 3.33Å
35	A	96.1	Very high	94.2	Very high	20 Å²	20	48 Å²	48	17%	0.165	27%	0.269	C	S	.	.	H	α-helix	trans	-63.2	-48	176.3	0	0	0	0	0	112	T31 S32 G38 A39 T95 F99	T31-A35 PolarHBondContact O-N 3.24Å; S32-A35 PolarHBondContact O-N 3.25Å; A35-G38 PolarHBondContact O-N 3.24Å; A35-A39 WeakPolarHBondContact O-CB 3.45Å; A35-A39 PolarHBondContact O-N 2.85Å; A35-T95 HydrophobicContact CB-CG2 3.93Å; A35-F99 HydrophobicContact CB-CD2 3.61Å; A35-F99 HydrophobicContact CB-CE2 3.56Å; A35-F99 HydrophobicContact CB-CG 4.35Å; A35-F99 HydrophobicContact CB-CZ 4.26Å
36	L	96.9	Very high	94.3	Very high	118 Å²	118	46 Å²	46	62%	0.618	26%	0.255	S	S	*	.	H	α-helix	trans	-66.5	-43.1	-179	-69.7	172.4	0	0	0	112.8	S32 V33 A39 T40	S32-L36 WeakPolarHBondContact O-CG 3.42Å; S32-L36 PolarHBondContact O-N 3.43Å; V33-L36 PolarHBondContact O-N 2.87Å; L36-A39 PolarHBondContact O-N 3.46Å; L36-T40 WeakPolarHBondContact O-CB 3.5Å; L36-T40 PolarHBondContact O-N 3.17Å; L36-T40 PolarHBondContact O-OG1 3.4Å
37	S	96.6	Very high	94.5	Very high	10 Å²	10	49.2 Å²	49.2	7%	0.07	28%	0.275	C	S	.	.	H	α-helix	trans	-67.6	-38.1	175.9	57.4	0	0	0	0	111.5	V33 S34 T40 A41 F54	V33-S37 VanDerWaalsContact O-CB 3.25Å; V33-S37 WeakPolarHBondContact O-CB 3.42Å; V33-S37 PolarHBondContact O-N 3.25Å; V33-S37 PolarHBondContact O-OG 3.26Å; S34-S37 PolarHBondContact O-OG 2.97Å; S37-T40 PolarHBondContact O-N 3.47Å; S37-A41 WeakPolarHBondContact O-CB 3.24Å; S37-A41 PolarHBondContact O-N 3.03Å; S37-F54 WeakPolarHBondContact O-CE1 3.37Å
38	G	97.3	Very high	94.6	Very high	0 Å²	0	47.7 Å²	47.7	0%	0	28%	0.279	C	S	.	.	H	α-helix	trans	-59.6	-48.7	172.9	0	0	0	0	0	111	S34 A35 T40 A41 G42 W100	S34-G38 PolarHBondContact O-N 3.05Å; A35-G38 PolarHBondContact O-N 3.24Å; G38-T40 VanDerWaalsContact C-N 3.32Å; G38-T40 PolarHBondContact O-N 3.25Å; G38-A41 PolarHBondContact O-N 3.28Å; G38-G42 PolarHBondContact O-N 3.36Å; G38-W100 WeakPolarHBondContact O-CA 3.48Å
39	A	97.1	Very high	94.7	Very high	19 Å²	19	46.3 Å²	46.3	16%	0.157	28%	0.282	C	S	.	.	H	α-helix	trans	-57.9	-44.5	175.6	0	0	0	0	0	112.8	A35 L36 G42 I43 L103	A35-A39 WeakPolarHBondContact O-CB 3.45Å; A35-A39 PolarHBondContact O-N 2.85Å; L36-A39 PolarHBondContact O-N 3.46Å; A39-G42 PolarHBondContact O-N 2.9Å; A39-I43 VanDerWaalsContact O-CG1 3.3Å; A39-I43 WeakPolarHBondContact O-CG1 3.4Å; A39-I43 PolarHBondContact O-N 2.98Å; A39-L103 HydrophobicContact CB-CD1 3.24Å
40	T	96.7	Very high	94.8	Very high	66 Å²	66	52.3 Å²	52.3	41%	0.405	30%	0.299	S	S	.	.	H	α-helix	trans	-62	-45.3	177.7	-53.1	0	0	0	0	111.3	L36 S37 G38 G42 I43 L44 F54	L36-T40 WeakPolarHBondContact O-CB 3.5Å; L36-T40 PolarHBondContact O-N 3.17Å; L36-T40 PolarHBondContact O-OG1 3.4Å; S37-T40 PolarHBondContact O-N 3.47Å; G38-T40 VanDerWaalsContact C-N 3.32Å; G38-T40 PolarHBondContact O-N 3.25Å; T40-G42 VanDerWaalsContact C-N 3.33Å; T40-G42 PolarHBondContact O-N 3.49Å; T40-I43 PolarHBondContact O-N 3.34Å; T40-L44 HydrophobicContact CG2-CD1 4.03Å; T40-L44 HydrophobicContact CG2-CG 4.48Å; T40-L44 WeakPolarHBondContact O-CB 3.49Å; T40-L44 VanDerWaalsContact O-CG 3.26Å; T40-L44 WeakPolarHBondContact O-CG 3.48Å; T40-L44 PolarHBondContact O-N 3.19Å; T40-F54 HydrophobicContact CG2-CE1 4.48Å; T40-F54 HydrophobicContact CG2-CZ 4.03Å
41	A	97	Very high	95.1	Very high	0 Å²	0	51.9 Å²	51.9	0%	0	30%	0.298	C	S	.	.	H	α-helix	trans	-64.5	-36.2	177.4	0	0	0	0	0	112.9	S37 G38 G45 L46 F54 Y96 W100	S37-A41 WeakPolarHBondContact O-CB 3.24Å; S37-A41 PolarHBondContact O-N 3.03Å; G38-A41 PolarHBondContact O-N 3.28Å; A41-G45 PolarHBondContact O-N 2.87Å; A41-L46 HydrophobicContact CB-CD1 4.11Å; A41-L46 PolarHBondContact O-N 3.16Å; A41-L46 VanDerWaalsContact O-N 3.12Å; A41-F54 HydrophobicContact CB-CD1 3.76Å; A41-F54 HydrophobicContact CB-CE1 4.16Å; A41-F54 HydrophobicContact CB-CG 4.45Å; A41-Y96 HydrophobicContact CB-CE2 4.13Å; A41-Y96 WeakPolarHBondContact CB-OH 3.14Å; A41-W100 HydrophobicContact CB-CG 4.25Å
42	G	96.4	Very high	95.1	Very high	0 Å²	0	53 Å²	53	0%	0	30%	0.297	C	S	.	.	H	α-helix	trans	-64.6	-49.4	175.4	0	0	0	0	0	112.2	G38 A39 T40 L44 G45 W100 Y104	G38-G42 PolarHBondContact O-N 3.36Å; A39-G42 PolarHBondContact O-N 2.9Å; T40-G42 VanDerWaalsContact C-N 3.33Å; T40-G42 PolarHBondContact O-N 3.49Å; G42-L44 VanDerWaalsContact C-N 3.35Å; G42-L44 PolarHBondContact O-N 2.76Å; G42-G45 PolarHBondContact O-N 3.35Å; G42-G45 VanDerWaalsContact O-N 3.08Å; G42-W100 VanDerWaalsContact CA-O 3.3Å; G42-W100 WeakPolarHBondContact CA-O 3.36Å; G42-Y104 WeakPolarHBondContact O-CA 3.42Å
43	I	95.5	Very high	95.2	Very high	96 Å²	96	55.4 Å²	55.4	49%	0.492	31%	0.306	S	S	.	.	H	α-helix	trans	-62.1	-44.1	177.5	-65.1	165.9	0	0	0	110.7	A39 T40 G45 V107 H108	A39-I43 VanDerWaalsContact O-CG1 3.3Å; A39-I43 WeakPolarHBondContact O-CG1 3.4Å; A39-I43 PolarHBondContact O-N 2.98Å; T40-I43 PolarHBondContact O-N 3.34Å; I43-G45 PolarHBondContact O-N 2.99Å; I43-G45 VanDerWaalsContact O-N 3.12Å; I43-V107 HydrophobicContact CG1-CG2 4.47Å; I43-H108 PolarHBondContact O-NE2 3.46Å
44	L	95.2	Very high	95.2	Very high	108 Å²	108	56 Å²	56	57%	0.565	31%	0.305	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.4	-11.2	177.2	-72.8	176.1	0	0	0	113.9	T40 G42 L46	T40-L44 HydrophobicContact CG2-CD1 4.03Å; T40-L44 HydrophobicContact CG2-CG 4.48Å; T40-L44 WeakPolarHBondContact O-CB 3.49Å; T40-L44 VanDerWaalsContact O-CG 3.26Å; T40-L44 WeakPolarHBondContact O-CG 3.48Å; T40-L44 PolarHBondContact O-N 3.19Å; G42-L44 VanDerWaalsContact C-N 3.35Å; G42-L44 PolarHBondContact O-N 2.76Å; L44-L46 VanDerWaalsContact C-N 3.33Å; L44-L46 HydrophobicContact CB-CG 4.15Å; L44-L46 PolarHBondContact O-N 2.9Å
45	G	93.2	Very high	95.2	Very high	20 Å²	20	56.3 Å²	56.3	21%	0.206	31%	0.306	C	S	.	.	T	Hydrogen-bonded Turn	trans	73.8	24.2	178.1	0	0	0	0	0	113.5	A41 G42 I43 T47 H108	A41-G45 PolarHBondContact O-N 2.87Å; G42-G45 PolarHBondContact O-N 3.35Å; G42-G45 VanDerWaalsContact O-N 3.08Å; I43-G45 PolarHBondContact O-N 2.99Å; I43-G45 VanDerWaalsContact O-N 3.12Å; G45-T47 PolarHBondContact O-N 3.09Å; G45-H108 WeakPolarHBondContact CA-NE2 3.25Å; G45-H108 PolarHBondContact N-NE2 3.15Å
46	L	93	Very high	95	Very high	47 Å²	47	60.6 Å²	60.6	25%	0.246	33%	0.325	C	S	.	.			trans	-67.7	129.7	179.5	-63.2	177.5	0	0	0	109.7	A41 L44 F54 W100	A41-L46 HydrophobicContact CB-CD1 4.11Å; A41-L46 PolarHBondContact O-N 3.16Å; A41-L46 VanDerWaalsContact O-N 3.12Å; L44-L46 VanDerWaalsContact C-N 3.33Å; L44-L46 HydrophobicContact CB-CG 4.15Å; L44-L46 PolarHBondContact O-N 2.9Å; L46-F54 HydrophobicContact CD1-CB 3.75Å; L46-F54 HydrophobicContact CD1-CD1 4.5Å; L46-F54 HydrophobicContact CD1-CD2 3.98Å; L46-F54 HydrophobicContact CD1-CG 3.83Å; L46-W100 VanDerWaalsContact O-CE2 3.27Å; L46-W100 VanDerWaalsContact O-CZ2 3.24Å; L46-W100 WeakPolarHBondContact O-CZ2 3.03Å; L46-W100 PolarHBondContact O-NE1 2.99Å
47	T	92.9	Very high	94.9	Very high	73 Å²	73	60.2 Å²	60.2	45%	0.448	32%	0.323	S	S	.	.			trans	-119.1	154.4	-179	57.3	0	0	0	0	112.1	G45 L49 Y50 Y104	G45-T47 PolarHBondContact O-N 3.09Å; T47-L49 PolarHBondContact O-N 2.92Å; T47-Y50 PolarHBondContact O-N 3.35Å; T47-Y104 HydrophobicContact CG2-CD2 4.44Å; T47-Y104 HydrophobicContact CG2-CE2 3.47Å; T47-Y104 VanDerWaalsContact CG2-CE2 3.47Å; T47-Y104 WeakPolarHBondContact CG2-OH 3.38Å
48	G	91.7	Very high	94.8	Very high	49 Å²	49	60.5 Å²	60.5	51%	0.505	33%	0.326	S	S	.	.	H	α-helix	trans	56.1	-131.9	174.3	0	0	0	0	0	113.8	Y50 G51 F52 W100	G48-Y50 VanDerWaalsContact C-N 3.29Å; G48-Y50 PolarHBondContact O-N 3.43Å; G48-G51 PolarHBondContact O-N 3.46Å; G48-F52 WeakPolarHBondContact O-CD2 3.42Å; G48-W100 WeakPolarHBondContact O-CH2 3.49Å
49	L	93.6	Very high	94.6	Very high	138 Å²	138	61 Å²	61	72%	0.723	33%	0.33	S	S	*	.	H	α-helix	trans	-64.2	-30.5	-176.2	-66.4	175.7	0	0	0	113.3	T47 G51 F52 I53	T47-L49 PolarHBondContact O-N 2.92Å; L49-G51 VanDerWaalsContact C-N 3.31Å; L49-G51 PolarHBondContact O-N 3.34Å; L49-F52 PolarHBondContact O-N 2.89Å; L49-F52 VanDerWaalsContact O-N 3.13Å; L49-I53 WeakPolarHBondContact O-CG1 3.31Å; L49-I53 PolarHBondContact O-N 2.79Å
50	Y	93.9	Very high	94.3	Very high	168 Å²	168	64.2 Å²	64.2	66%	0.659	35%	0.347	S	S	*	.	H	α-helix	trans	-64	-36.9	-179.5	-66.3	-69.5	0	0	0	112.3	T47 G48 I53 F54	T47-Y50 PolarHBondContact O-N 3.35Å; G48-Y50 VanDerWaalsContact C-N 3.29Å; G48-Y50 PolarHBondContact O-N 3.43Å; Y50-I53 HydrophobicContact CD1-CD1 4.47Å; Y50-I53 PolarHBondContact O-N 3.34Å; Y50-F54 PolarHBondContact O-N 2.89Å
51	G	94.9	Very high	94.2	Very high	0 Å²	0	66 Å²	66	0%	0	35%	0.353	C	S	.	.	H	α-helix	trans	-65.2	-38.3	173.3	0	0	0	0	0	112.5	G48 L49 F54 Y55 Y96	G48-G51 PolarHBondContact O-N 3.46Å; L49-G51 VanDerWaalsContact C-N 3.31Å; L49-G51 PolarHBondContact O-N 3.34Å; G51-F54 PolarHBondContact O-N 2.95Å; G51-Y55 PolarHBondContact O-N 3.12Å; G51-Y55 VanDerWaalsContact O-N 3.17Å; G51-Y96 PolarHBondContact O-OH 3.35Å
52	F	94.5	Very high	93.9	Very high	93 Å²	93	67 Å²	67	41%	0.408	36%	0.359	S	S	.	.	H	α-helix	trans	-69.8	-36.2	175	-71.8	-72.4	0	0	0	113	G48 L49 F54 Y55 L56 L93 V97 W100	G48-F52 WeakPolarHBondContact O-CD2 3.42Å; L49-F52 PolarHBondContact O-N 2.89Å; L49-F52 VanDerWaalsContact O-N 3.13Å; F52-F54 VanDerWaalsContact C-N 3.29Å; F52-F54 PolarHBondContact O-N 3.18Å; F52-Y55 WeakPolarHBondContact O-CB 3.27Å; F52-Y55 PolarHBondContact O-N 3.41Å; F52-L56 PolarHBondContact O-N 3.29Å; F52-L56 VanDerWaalsContact O-N 3.1Å; F52-L93 HydrophobicContact CD1-CD1 4.17Å; F52-L93 HydrophobicContact CE1-CD1 4.17Å; F52-V97 HydrophobicContact CE1-CG2 4.12Å; F52-W100 HydrophobicContact CD1-CZ3 4.44Å; F52-W100 HydrophobicContact CD2-CH2 4.14Å; F52-W100 HydrophobicContact CD2-CZ3 4.14Å; F52-W100 HydrophobicContact CE1-CZ3 4.21Å; F52-W100 HydrophobicContact CE2-CH2 4.07Å; F52-W100 AromaticContact CE2-CZ3 3.9Å; F52-W100 HydrophobicContact CE2-CZ3 3.9Å; F52-W100 HydrophobicContact CG-CZ3 4.41Å; F52-W100 AromaticContact CZ-CZ3 3.94Å; F52-W100 HydrophobicContact CZ-CZ3 3.94Å
53	I	95.6	Very high	93.6	Very high	87 Å²	87	67.4 Å²	67.4	45%	0.446	36%	0.362	S	S	.	.	H	α-helix	trans	-60.5	-43.4	173.4	-67.9	166.3	0	0	0	109.9	L49 Y50 Y55 L56 L57	L49-I53 WeakPolarHBondContact O-CG1 3.31Å; L49-I53 PolarHBondContact O-N 2.79Å; Y50-I53 HydrophobicContact CD1-CD1 4.47Å; Y50-I53 PolarHBondContact O-N 3.34Å; I53-Y55 VanDerWaalsContact C-N 3.31Å; I53-Y55 PolarHBondContact O-N 2.96Å; I53-L56 PolarHBondContact O-N 2.99Å; I53-L57 HydrophobicContact CG2-CD1 4.11Å; I53-L57 HydrophobicContact CG2-CG 4.37Å; I53-L57 WeakPolarHBondContact O-CG 3.33Å; I53-L57 PolarHBondContact O-N 3.33Å
54	F	95.3	Very high	93.3	Very high	58 Å²	58	67.3 Å²	67.3	25%	0.254	36%	0.362	S	S	.	.	H	α-helix	trans	-59.9	-40.4	176.9	-170.7	-96.9	0	0	0	112.5	S37 T40 A41 L46 Y50 G51 F52 L56 L57 A58 Y96	S37-F54 WeakPolarHBondContact O-CE1 3.37Å; T40-F54 HydrophobicContact CG2-CE1 4.48Å; T40-F54 HydrophobicContact CG2-CZ 4.03Å; A41-F54 HydrophobicContact CB-CD1 3.76Å; A41-F54 HydrophobicContact CB-CE1 4.16Å; A41-F54 HydrophobicContact CB-CG 4.45Å; L46-F54 HydrophobicContact CD1-CB 3.75Å; L46-F54 HydrophobicContact CD1-CD1 4.5Å; L46-F54 HydrophobicContact CD1-CD2 3.98Å; L46-F54 HydrophobicContact CD1-CG 3.83Å; Y50-F54 PolarHBondContact O-N 2.89Å; G51-F54 PolarHBondContact O-N 2.95Å; F52-F54 VanDerWaalsContact C-N 3.29Å; F52-F54 PolarHBondContact O-N 3.18Å; F54-L56 PolarHBondContact O-N 2.87Å; F54-L57 PolarHBondContact O-N 3.43Å; F54-A58 WeakPolarHBondContact O-CB 3.26Å; F54-A58 PolarHBondContact O-N 2.89Å; F54-Y96 HydrophobicContact CD1-CE2 4.23Å
55	Y	95.2	Very high	93.1	Very high	13 Å²	13	66.9 Å²	66.9	5%	0.051	36%	0.359	C	S	.	.	H	α-helix	trans	-60.1	-45.8	173.7	177.6	-110.1	0	0	0	113.1	G51 F52 I53 L57 A58 S59 L89 G92 L93 Y96	G51-Y55 PolarHBondContact O-N 3.12Å; G51-Y55 VanDerWaalsContact O-N 3.17Å; F52-Y55 WeakPolarHBondContact O-CB 3.27Å; F52-Y55 PolarHBondContact O-N 3.41Å; I53-Y55 VanDerWaalsContact C-N 3.31Å; I53-Y55 PolarHBondContact O-N 2.96Å; Y55-L57 VanDerWaalsContact C-N 3.34Å; Y55-A58 PolarHBondContact O-N 3.16Å; Y55-S59 WeakPolarHBondContact CE2-OG 3.39Å; Y55-S59 VanDerWaalsContact O-CB 3.31Å; Y55-S59 WeakPolarHBondContact O-CB 3.47Å; Y55-S59 PolarHBondContact O-N 3.02Å; Y55-S59 PolarHBondContact O-OG 3.21Å; Y55-L89 PolarHBondContact OH-O 3.24Å; Y55-G92 VanDerWaalsContact OH-C 3.23Å; Y55-L93 HydrophobicContact CD1-CD1 3.45Å; Y55-L93 VanDerWaalsContact CD1-CD1 3.45Å; Y55-L93 HydrophobicContact CE1-CB 3.91Å; Y55-L93 HydrophobicContact CE1-CD1 3.56Å; Y55-L93 HydrophobicContact CE1-CG 4.33Å; Y55-L93 HydrophobicContact CG-CD1 3.98Å; Y55-L93 PolarHBondContact OH-N 3.49Å; Y55-Y96 AromaticContact CD2-CD1 3.87Å; Y55-Y96 HydrophobicContact CD2-CD1 3.87Å; Y55-Y96 AromaticContact CD2-CD2 3.53Å; Y55-Y96 HydrophobicContact CD2-CD2 3.53Å; Y55-Y96 HydrophobicContact CD2-CE1 4.45Å; Y55-Y96 HydrophobicContact CD2-CE2 4.14Å; Y55-Y96 AromaticContact CD2-CG 3.38Å; Y55-Y96 HydrophobicContact CD2-CG 3.38Å; Y55-Y96 HydrophobicContact CE2-CD2 4.38Å; Y55-Y96 HydrophobicContact CE2-CG 4.07Å; Y55-Y96 HydrophobicContact CG-CD1 4.03Å; Y55-Y96 HydrophobicContact CG-CD2 4.29Å; Y55-Y96 HydrophobicContact CG-CE1 4.33Å; Y55-Y96 HydrophobicContact CG-CG 4.02Å
56	L	93.5	Very high	92.9	Very high	109 Å²	109	67.5 Å²	67.5	57%	0.571	36%	0.358	S	S	*	.	H	α-helix	trans	-62.6	-43.2	178	-68.9	178.5	0	0	0	111	F52 I53 F54 S59 V60	F52-L56 PolarHBondContact O-N 3.29Å; F52-L56 VanDerWaalsContact O-N 3.1Å; I53-L56 PolarHBondContact O-N 2.99Å; F54-L56 PolarHBondContact O-N 2.87Å; L56-S59 PolarHBondContact O-N 2.75Å; L56-V60 WeakPolarHBondContact O-CB 3.44Å; L56-V60 VanDerWaalsContact O-CG2 3.27Å; L56-V60 WeakPolarHBondContact O-CG2 3.38Å; L56-V60 PolarHBondContact O-N 2.88Å
57	L	94.8	Very high	92.5	Very high	111 Å²	111	66.9 Å²	66.9	58%	0.581	35%	0.354	S	S	*	.	H	α-helix	trans	-60.2	-47.2	175.7	-69.7	175.2	0	0	0	111.7	I53 F54 Y55 S59 V60 L61	I53-L57 HydrophobicContact CG2-CD1 4.11Å; I53-L57 HydrophobicContact CG2-CG 4.37Å; I53-L57 WeakPolarHBondContact O-CG 3.33Å; I53-L57 PolarHBondContact O-N 3.33Å; F54-L57 PolarHBondContact O-N 3.43Å; Y55-L57 VanDerWaalsContact C-N 3.34Å; L57-S59 VanDerWaalsContact C-N 3.35Å; L57-S59 PolarHBondContact O-N 2.91Å; L57-V60 PolarHBondContact O-N 3.42Å; L57-L61 VanDerWaalsContact O-CB 3.24Å; L57-L61 WeakPolarHBondContact O-CB 3.21Å; L57-L61 PolarHBondContact O-N 3.28Å
58	A	94	Very high	92.2	Very high	16 Å²	16	69.9 Å²	69.9	13%	0.132	37%	0.367	C	S	.	.	H	α-helix	trans	-62.3	-41.6	177.6	0	0	0	0	0	112.2	F54 Y55 L61 L62	F54-A58 WeakPolarHBondContact O-CB 3.26Å; F54-A58 PolarHBondContact O-N 2.89Å; Y55-A58 PolarHBondContact O-N 3.16Å; A58-L61 PolarHBondContact O-N 2.81Å; A58-L62 WeakPolarHBondContact O-CB 3.34Å; A58-L62 PolarHBondContact O-N 2.92Å
59	S	92.6	Very high	91.9	Very high	11 Å²	11	76.2 Å²	76.2	8%	0.077	38%	0.381	C	S	.	.	H	α-helix	trans	-66.8	-42.1	178.8	-66.7	0	0	0	0	112.9	Y55 L56 L57 S63	Y55-S59 WeakPolarHBondContact CE2-OG 3.39Å; Y55-S59 VanDerWaalsContact O-CB 3.31Å; Y55-S59 WeakPolarHBondContact O-CB 3.47Å; Y55-S59 PolarHBondContact O-N 3.02Å; Y55-S59 PolarHBondContact O-OG 3.21Å; L56-S59 PolarHBondContact O-N 2.75Å; L57-S59 VanDerWaalsContact C-N 3.35Å; L57-S59 PolarHBondContact O-N 2.91Å; S59-S63 WeakPolarHBondContact O-CB 3.45Å; S59-S63 PolarHBondContact O-N 2.86Å; S59-S63 PolarHBondContact O-OG 2.69Å
60	V	91.8	Very high	91.3	Very high	85 Å²	85	70.5 Å²	70.5	52%	0.515	35%	0.353	S	S	.	.	H	α-helix	trans	-66.1	-44.8	174.8	170.2	0	0	0	0	109.9	L56 L57 L62 S63 L64	L56-V60 WeakPolarHBondContact O-CB 3.44Å; L56-V60 VanDerWaalsContact O-CG2 3.27Å; L56-V60 WeakPolarHBondContact O-CG2 3.38Å; L56-V60 PolarHBondContact O-N 2.88Å; L57-V60 PolarHBondContact O-N 3.42Å; V60-L62 PolarHBondContact O-N 3.17Å; V60-S63 WeakPolarHBondContact O-CB 3.25Å; V60-S63 PolarHBondContact O-N 2.83Å; V60-S63 VanDerWaalsContact O-N 3.11Å; V60-L64 HydrophobicContact CG1-CD1 4.09Å; V60-L64 HydrophobicContact CG1-CG 4.33Å; V60-L64 WeakPolarHBondContact O-CG 3.47Å; V60-L64 PolarHBondContact O-N 3.26Å
61	L	93.2	Very high	90.5	Very high	103 Å²	103	64 Å²	64	54%	0.539	34%	0.337	S	S	.	.	H	α-helix	trans	-58.8	-47.5	177.7	-178.7	61.8	0	0	0	111.5	L57 A58 S63 L64 L65	L57-L61 VanDerWaalsContact O-CB 3.24Å; L57-L61 WeakPolarHBondContact O-CB 3.21Å; L57-L61 PolarHBondContact O-N 3.28Å; A58-L61 PolarHBondContact O-N 2.81Å; L61-S63 VanDerWaalsContact C-N 3.3Å; L61-S63 PolarHBondContact O-N 3.32Å; L61-L64 PolarHBondContact O-N 3.41Å; L61-L65 HydrophobicContact CG-CD1 4.31Å; L61-L65 WeakPolarHBondContact O-CG 3.42Å; L61-L65 PolarHBondContact O-N 3.24Å
62	L	91.5	Very high	89.4	Confident	21 Å²	21	75.3 Å²	75.3	11%	0.11	38%	0.38	C	S	.	.	H	α-helix	trans	-57.5	-45.4	174.2	177.8	61.2	0	0	0	111.5	R30 V33 A58 V60 L64 L65 L66	R30-L62 HydrophobicContact CB-CD2 4.31Å; R30-L62 HydrophobicContact CG-CD2 3.74Å; V33-L62 HydrophobicContact CB-CD2 3.98Å; V33-L62 HydrophobicContact CG1-CB 4.34Å; V33-L62 HydrophobicContact CG1-CD2 4.16Å; V33-L62 HydrophobicContact CG2-CD1 3.96Å; V33-L62 HydrophobicContact CG2-CD2 4.07Å; A58-L62 WeakPolarHBondContact O-CB 3.34Å; A58-L62 PolarHBondContact O-N 2.92Å; V60-L62 PolarHBondContact O-N 3.17Å; L62-L64 VanDerWaalsContact C-N 3.32Å; L62-L64 PolarHBondContact O-N 2.98Å; L62-L65 PolarHBondContact O-N 3.5Å; L62-L66 HydrophobicContact CD1-CD1 4.33Å; L62-L66 HydrophobicContact CD1-CG 4.2Å; L62-L66 HydrophobicContact CG-CD1 4.08Å; L62-L66 HydrophobicContact CG-CG 4.38Å; L62-L66 VanDerWaalsContact O-CG 3.3Å; L62-L66 WeakPolarHBondContact O-CG 3.15Å; L62-L66 PolarHBondContact O-N 3.1Å
63	S	89.5	Confident	88.3	Confident	10 Å²	10	79.4 Å²	79.4	7%	0.07	39%	0.392	C	S	.	.	H	α-helix	trans	-62.7	-39.9	180	-56.9	0	0	0	0	111.6	S59 V60 L61 L66 I67	S59-S63 WeakPolarHBondContact O-CB 3.45Å; S59-S63 PolarHBondContact O-N 2.86Å; S59-S63 PolarHBondContact O-OG 2.69Å; V60-S63 WeakPolarHBondContact O-CB 3.25Å; V60-S63 PolarHBondContact O-N 2.83Å; V60-S63 VanDerWaalsContact O-N 3.11Å; L61-S63 VanDerWaalsContact C-N 3.3Å; L61-S63 PolarHBondContact O-N 3.32Å; S63-L66 PolarHBondContact O-N 3.18Å; S63-I67 WeakPolarHBondContact O-CD1 3.3Å; S63-I67 VanDerWaalsContact O-CG1 3.23Å; S63-I67 WeakPolarHBondContact O-CG1 3.36Å; S63-I67 PolarHBondContact O-N 2.58Å
64	L	90	Very high	86.9	Confident	94 Å²	94	78.4 Å²	78.4	49%	0.492	38%	0.383	S	S	.	.	H	α-helix	trans	-62.6	-46.3	173.3	-70	173.8	0	0	0	111.7	V60 L61 L62 L66 I67 L68	V60-L64 HydrophobicContact CG1-CD1 4.09Å; V60-L64 HydrophobicContact CG1-CG 4.33Å; V60-L64 WeakPolarHBondContact O-CG 3.47Å; V60-L64 PolarHBondContact O-N 3.26Å; L61-L64 PolarHBondContact O-N 3.41Å; L62-L64 VanDerWaalsContact C-N 3.32Å; L62-L64 PolarHBondContact O-N 2.98Å; L64-L66 VanDerWaalsContact C-N 3.31Å; L64-L66 PolarHBondContact O-N 3.3Å; L64-I67 PolarHBondContact O-N 3.17Å; L64-L68 VanDerWaalsContact O-CG 3.31Å; L64-L68 WeakPolarHBondContact O-CG 3.4Å; L64-L68 PolarHBondContact O-N 3.38Å
65	L	90.6	Very high	85.7	Confident	98 Å²	98	81.6 Å²	81.6	51%	0.513	40%	0.403	S	S	.	.	H	α-helix	trans	-61.2	-40	176.9	-67.8	172.4	0	0	0	111.9	L61 L62 L68 K69	L61-L65 HydrophobicContact CG-CD1 4.31Å; L61-L65 WeakPolarHBondContact O-CG 3.42Å; L61-L65 PolarHBondContact O-N 3.24Å; L62-L65 PolarHBondContact O-N 3.5Å; L65-L68 PolarHBondContact O-N 2.92Å; L65-K69 VanDerWaalsContact O-CB 3.31Å; L65-K69 WeakPolarHBondContact O-CB 3.34Å; L65-K69 PolarHBondContact O-N 3.46Å
66	L	88.2	Confident	84.4	Confident	34 Å²	34	86.8 Å²	86.8	18%	0.178	43%	0.426	C	S	.	.	H	α-helix	trans	-65.6	-39.7	175.7	-70.9	174.9	0	0	0	112.1	L26 L62 S63 L64 K69 A70	L26-L66 HydrophobicContact CD1-CD1 4.18Å; L26-L66 HydrophobicContact CG-CD1 4.29Å; L62-L66 HydrophobicContact CD1-CD1 4.33Å; L62-L66 HydrophobicContact CD1-CG 4.2Å; L62-L66 HydrophobicContact CG-CD1 4.08Å; L62-L66 HydrophobicContact CG-CG 4.38Å; L62-L66 VanDerWaalsContact O-CG 3.3Å; L62-L66 WeakPolarHBondContact O-CG 3.15Å; L62-L66 PolarHBondContact O-N 3.1Å; S63-L66 PolarHBondContact O-N 3.18Å; L64-L66 VanDerWaalsContact C-N 3.31Å; L64-L66 PolarHBondContact O-N 3.3Å; L66-K69 PolarHBondContact O-N 2.9Å; L66-A70 VanDerWaalsContact O-CB 3.28Å; L66-A70 WeakPolarHBondContact O-CB 3.3Å; L66-A70 PolarHBondContact O-N 2.96Å
67	I	85.3	Confident	83.3	Confident	33 Å²	33	85.9 Å²	85.9	17%	0.169	42%	0.416	C	S	.	.	H	α-helix	trans	-65.1	-44.7	175.5	-68.6	160.7	0	0	0	110.6	S63 L64 K69 A70 G71 W74 F85	S63-I67 WeakPolarHBondContact O-CD1 3.3Å; S63-I67 VanDerWaalsContact O-CG1 3.23Å; S63-I67 WeakPolarHBondContact O-CG1 3.36Å; S63-I67 PolarHBondContact O-N 2.58Å; L64-I67 PolarHBondContact O-N 3.17Å; I67-K69 VanDerWaalsContact C-N 3.31Å; I67-K69 PolarHBondContact O-N 3.38Å; I67-A70 PolarHBondContact O-N 3.03Å; I67-G71 PolarHBondContact O-N 3.12Å; I67-W74 HydrophobicContact CG1-CZ3 4.47Å; I67-W74 HydrophobicContact CG2-CH2 4.21Å; I67-W74 HydrophobicContact CG2-CZ3 3.99Å; I67-F85 HydrophobicContact CD1-CD1 4.36Å; I67-F85 HydrophobicContact CD1-CE1 3.53Å; I67-F85 HydrophobicContact CD1-CE2 4.04Å; I67-F85 HydrophobicContact CD1-CZ 3.35Å; I67-F85 HydrophobicContact CG1-CZ 4.35Å
68	L	86.8	Confident	82	Confident	136 Å²	136	82.1 Å²	82.1	71%	0.712	39%	0.394	S	S	*	.	H	α-helix	trans	-59.7	-42.7	175.1	-70.7	171.4	0	0	0	111.2	L64 L65 G71	L64-L68 VanDerWaalsContact O-CG 3.31Å; L64-L68 WeakPolarHBondContact O-CG 3.4Å; L64-L68 PolarHBondContact O-N 3.38Å; L65-L68 PolarHBondContact O-N 2.92Å; L68-G71 PolarHBondContact O-N 3.03Å
69	K	85.9	Confident	80.7	Confident	183 Å²	183	88.6 Å²	88.6	80%	0.796	42%	0.419	S	S	*	.	H	α-helix	trans	-69	-41.6	178.7	-176.2	62.1	174.5	175.9	0	113.1	L65 L66 I67 G71	L65-K69 VanDerWaalsContact O-CB 3.31Å; L65-K69 WeakPolarHBondContact O-CB 3.34Å; L65-K69 PolarHBondContact O-N 3.46Å; L66-K69 PolarHBondContact O-N 2.9Å; I67-K69 VanDerWaalsContact C-N 3.31Å; I67-K69 PolarHBondContact O-N 3.38Å; K69-G71 PolarHBondContact O-N 3.47Å
70	A	80.5	Confident	79.4	Confident	17 Å²	17	90.7 Å²	90.7	14%	0.14	43%	0.434	C	S	.	.	H	α-helix	trans	-67.8	-27.7	176.7	0	0	0	0	0	112	L66 I67	L66-A70 VanDerWaalsContact O-CB 3.28Å; L66-A70 WeakPolarHBondContact O-CB 3.3Å; L66-A70 PolarHBondContact O-N 2.96Å; I67-A70 PolarHBondContact O-N 3.03Å
71	G	77.2	Confident	78.1	Confident	31 Å²	31	94.2 Å²	94.2	32%	0.32	44%	0.438	S	S	.	.	G	3₁₀ helix	trans	59.4	-160.5	179	0	0	0	0	0	113.1	I67 L68 K69 R73	I67-G71 PolarHBondContact O-N 3.12Å; L68-G71 PolarHBondContact O-N 3.03Å; K69-G71 PolarHBondContact O-N 3.47Å; G71-R73 PolarHBondContact O-N 2.97Å
72	R	70.7	Confident	77	Confident	238 Å²	238	98.7 Å²	98.7	90%	0.898	45%	0.448	S	S	*	.	G	3₁₀ helix	trans	-67.8	-7.1	-177.6	-158.5	157.8	78	155.7	1.5	114.2	W74	R72-W74 PolarHBondContact O-NE1 3.44Å
73	R	71.5	Confident	75.9	Confident	179 Å²	179	100.3 Å²	100.3	68%	0.675	46%	0.46	S	S	*	.	G	3₁₀ helix	trans	-109.7	23.9	-175	-69.7	-171.5	-79.4	-173.7	-4.5	114.4	G71 N75 K76 Y77	G71-R73 PolarHBondContact O-N 2.97Å; R73-N75 PolarHBondContact O-N 3.46Å; R73-K76 WeakPolarHBondContact O-CB 3.36Å; R73-K76 PolarHBondContact O-N 3.29Å; R73-Y77 HydrophobicContact CB-CE2 4.36Å; R73-Y77 WeakPolarHBondContact O-CD2 3.16Å
74	W	67.5	Low	75	Confident	66 Å²	66	99.9 Å²	99.9	25%	0.25	46%	0.457	C	S	.	.	H	α-helix	trans	-34	-45.6	166.9	11.8	28	0	0	0	116	I67 R72 K76 Y77 F78	I67-W74 HydrophobicContact CG1-CZ3 4.47Å; I67-W74 HydrophobicContact CG2-CH2 4.21Å; I67-W74 HydrophobicContact CG2-CZ3 3.99Å; R72-W74 PolarHBondContact O-NE1 3.44Å; W74-K76 PolarHBondContact O-N 2.9Å; W74-Y77 PolarHBondContact O-N 3.23Å; W74-F78 PolarHBondContact O-N 3.37Å; W74-F78 VanDerWaalsContact O-N 3.14Å
75	N	69	Low	73.8	Confident	126 Å²	126	100.1 Å²	100.1	67%	0.674	45%	0.454	S	S	*	.	H	α-helix	trans	-62.2	-16.1	-177.5	-158.9	46.3	0	0	0	114.1	R73	R73-N75 PolarHBondContact O-N 3.46Å
76	K	68.9	Low	73	Confident	122 Å²	122	99.9 Å²	99.9	53%	0.53	46%	0.457	S	S	.	.	H	α-helix	trans	-83.4	-27.6	175.5	-169	178	179.9	-175.9	0	112.5	R73 W74	R73-K76 WeakPolarHBondContact O-CB 3.36Å; R73-K76 PolarHBondContact O-N 3.29Å; W74-K76 PolarHBondContact O-N 2.9Å
77	Y	69.2	Low	72.3	Confident	90 Å²	90	99.1 Å²	99.1	35%	0.353	46%	0.457	S	S	.	.	H	α-helix	trans	-99.4	-32.6	-170.7	-58.5	-70.1	0	0	0	113	N22 R73 W74	N22-Y77 PolarHBondContact ND2-O 3.41Å; R73-Y77 HydrophobicContact CB-CE2 4.36Å; R73-Y77 WeakPolarHBondContact O-CD2 3.16Å; W74-Y77 PolarHBondContact O-N 3.23Å
78	F	68.8	Low	71.8	Confident	31 Å²	31	99.2 Å²	99.2	14%	0.136	47%	0.466	C	S	.	.			trans	-131.5	138.9	-176.2	-67	-83.3	0	0	0	111.5	N22 L26 W74 S80 L84	N22-F78 HydrophobicContact CB-CE1 4.12Å; N22-F78 HydrophobicContact CB-CZ 4.07Å; L26-F78 HydrophobicContact CB-CE1 4.31Å; L26-F78 HydrophobicContact CB-CZ 4.3Å; L26-F78 HydrophobicContact CD1-CE1 3.77Å; L26-F78 HydrophobicContact CD1-CZ 3.68Å; W74-F78 PolarHBondContact O-N 3.37Å; W74-F78 VanDerWaalsContact O-N 3.14Å; F78-S80 VanDerWaalsContact C-N 3.29Å; F78-S80 PolarHBondContact O-N 2.83Å; F78-L84 HydrophobicContact CB-CD1 4.48Å; F78-L84 HydrophobicContact CD2-CD1 4.12Å; F78-L84 HydrophobicContact CD2-CD2 3.67Å; F78-L84 HydrophobicContact CD2-CG 4.14Å; F78-L84 HydrophobicContact CE1-CD2 4.45Å; F78-L84 HydrophobicContact CE2-CD2 3.6Å; F78-L84 HydrophobicContact CG-CD1 4.42Å; F78-L84 HydrophobicContact CG-CD2 4.15Å; F78-L84 HydrophobicContact CG-CG 4.27Å; F78-L84 HydrophobicContact CZ-CD2 4.01Å
79	K	65.7	Low	71.5	Confident	152 Å²	152	95.4 Å²	95.4	66%	0.661	45%	0.446	S	S	*	.	S	Bend	trans	-70.5	-21.9	178.5	-174.2	162.6	-173.6	172.6	0	113.5	F13 V19	F13-K79 HydrophobicContact CE1-CB 3.83Å; F13-K79 HydrophobicContact CE1-CG 4.13Å; F13-K79 HydrophobicContact CE2-CD 4.11Å; F13-K79 HydrophobicContact CE2-CG 3.98Å; F13-K79 HydrophobicContact CZ-CB 3.74Å; F13-K79 HydrophobicContact CZ-CD 4.1Å; F13-K79 HydrophobicContact CZ-CG 3.52Å; V19-K79 HydrophobicContact CG1-CB 4.46Å
80	S	66.4	Low	71.5	Confident	55 Å²	55	92.8 Å²	92.8	39%	0.385	44%	0.44	S	S	.	.			trans	-146.4	150.7	179	178.7	0	0	0	0	110.9	F78 R82 P83	F78-S80 VanDerWaalsContact C-N 3.29Å; F78-S80 PolarHBondContact O-N 2.83Å; S80-R82 VanDerWaalsContact C-N 3.35Å; S80-R82 PolarHBondContact OG-N 3.28Å; S80-P83 WeakPolarHBondContact O-CD 3.19Å
81	R	64.2	Low	71.8	Confident	159 Å²	159	94 Å²	94	60%	0.6	45%	0.454	S	S	*	.	S	Bend	trans	-76.5	-20.8	172.7	-63.4	-172.5	-173.2	-170.8	3.2	112.9	L84 F85	R81-L84 WeakPolarHBondContact O-CB 3.43Å; R81-L84 PolarHBondContact O-N 2.91Å; R81-F85 PolarHBondContact O-N 3.4Å
82	R	69.1	Low	72.5	Confident	197 Å²	197	92.7 Å²	92.7	74%	0.743	44%	0.44	S	S	*	.	H	α-helix	trans	-61.3	-45.9	-174.3	-63.5	-173.4	-179.5	-178.5	-0.1	113	S80 L84 F85 T86	S80-R82 VanDerWaalsContact C-N 3.35Å; S80-R82 PolarHBondContact OG-N 3.28Å; R82-L84 PolarHBondContact O-N 2.88Å; R82-F85 PolarHBondContact O-N 3.29Å; R82-F85 VanDerWaalsContact O-N 3.17Å; R82-T86 PolarHBondContact O-N 2.93Å; R82-T86 PolarHBondContact O-OG1 3.44Å
83	P	68.6	Low	73.6	Confident	55 Å²	55	83.8 Å²	83.8	36%	0.357	41%	0.41	S	S	.	.	H	α-helix	trans	-63.1	-28.2	178.2	-22.1	34.3	0	0	0	114	R30 S80 G87	R30-P83 PolarHBondContact NH2-O 3.44Å; S80-P83 WeakPolarHBondContact O-CD 3.19Å; P83-G87 WeakPolarHBondContact O-CA 3.29Å; P83-G87 PolarHBondContact O-N 3.34Å; P83-G87 VanDerWaalsContact O-N 3.16Å
84	L	70.2	Confident	74.7	Confident	2 Å²	2	82.2 Å²	82.2	1%	0.01	41%	0.409	C	S	.	.	H	α-helix	trans	-67.4	-35.9	176.9	-70.3	171.2	0	0	0	112.2	L26 R30 F78 R81 R82	L26-L84 HydrophobicContact CD1-CD2 3.68Å; R30-L84 VanDerWaalsContact NH2-C 3.31Å; R30-L84 PolarHBondContact NH2-O 3.11Å; F78-L84 HydrophobicContact CB-CD1 4.48Å; F78-L84 HydrophobicContact CD2-CD1 4.12Å; F78-L84 HydrophobicContact CD2-CD2 3.67Å; F78-L84 HydrophobicContact CD2-CG 4.14Å; F78-L84 HydrophobicContact CE1-CD2 4.45Å; F78-L84 HydrophobicContact CE2-CD2 3.6Å; F78-L84 HydrophobicContact CG-CD1 4.42Å; F78-L84 HydrophobicContact CG-CD2 4.15Å; F78-L84 HydrophobicContact CG-CG 4.27Å; F78-L84 HydrophobicContact CZ-CD2 4.01Å; R81-L84 WeakPolarHBondContact O-CB 3.43Å; R81-L84 PolarHBondContact O-N 2.91Å; R82-L84 PolarHBondContact O-N 2.88Å
85	F	65.9	Low	76	Confident	99 Å²	99	80.8 Å²	80.8	43%	0.434	41%	0.407	S	S	.	.	H	α-helix	trans	-92.6	-48.8	-179.4	-79.9	-84.2	0	0	0	112.8	I67 R81 R82	I67-F85 HydrophobicContact CD1-CD1 4.36Å; I67-F85 HydrophobicContact CD1-CE1 3.53Å; I67-F85 HydrophobicContact CD1-CE2 4.04Å; I67-F85 HydrophobicContact CD1-CZ 3.35Å; I67-F85 HydrophobicContact CG1-CZ 4.35Å; R81-F85 PolarHBondContact O-N 3.4Å; R82-F85 PolarHBondContact O-N 3.29Å; R82-F85 VanDerWaalsContact O-N 3.17Å
86	T	72.7	Confident	77.3	Confident	93 Å²	93	74.8 Å²	74.8	57%	0.571	38%	0.375	S	S	*	.	H	α-helix	trans	-119.5	-4.4	-169	59.3	0	0	0	0	114.5	R82 G88 L89	R82-T86 PolarHBondContact O-N 2.93Å; R82-T86 PolarHBondContact O-OG1 3.44Å; T86-G88 PolarHBondContact O-N 3.18Å; T86-L89 HydrophobicContact CG2-CD1 4.46Å
87	G	73.6	Confident	78.6	Confident	17 Å²	17	71.2 Å²	71.2	18%	0.175	36%	0.363	C	S	.	.	T	Hydrogen-bonded Turn	trans	-58.4	128.6	178.8	0	0	0	0	0	110.7	R30 P83 L89	R30-G87 WeakPolarHBondContact CD-O 3.35Å; R30-G87 PolarHBondContact NE-O 3.37Å; P83-G87 WeakPolarHBondContact O-CA 3.29Å; P83-G87 PolarHBondContact O-N 3.34Å; P83-G87 VanDerWaalsContact O-N 3.16Å; G87-L89 PolarHBondContact O-N 3.46Å; G87-L89 VanDerWaalsContact O-N 3.09Å
88	G	75.9	Confident	79.8	Confident	36 Å²	36	71.9 Å²	71.9	37%	0.371	37%	0.372	S	S	.	.	T	Hydrogen-bonded Turn	trans	68.9	5.6	171.6	0	0	0	0	0	116.9	T86 I90 G91 G92	T86-G88 PolarHBondContact O-N 3.18Å; G88-I90 VanDerWaalsContact C-N 3.27Å; G88-I90 PolarHBondContact O-N 3.3Å; G88-G91 PolarHBondContact O-N 3.31Å; G88-G92 PolarHBondContact O-N 3.16Å
89	L	80.7	Confident	81.2	Confident	55 Å²	55	74 Å²	74	29%	0.288	38%	0.382	S	S	.	.	H	α-helix	trans	-61.1	-35.2	178.7	-69.8	-179.5	0	0	0	113	Y55 T86 G87 L93	Y55-L89 PolarHBondContact OH-O 3.24Å; T86-L89 HydrophobicContact CG2-CD1 4.46Å; G87-L89 PolarHBondContact O-N 3.46Å; G87-L89 VanDerWaalsContact O-N 3.09Å; L89-L93 PolarHBondContact O-N 3.22Å
90	I	86.3	Confident	82.7	Confident	129 Å²	129	67.7 Å²	67.7	66%	0.662	35%	0.354	S	S	*	.	H	α-helix	trans	-75.7	-42.4	177.5	-60.8	172	0	0	0	110.1	G88 G92 L93 F94	G88-I90 VanDerWaalsContact C-N 3.27Å; G88-I90 PolarHBondContact O-N 3.3Å; I90-G92 PolarHBondContact O-N 3.05Å; I90-L93 WeakPolarHBondContact O-CB 3.48Å; I90-L93 PolarHBondContact O-N 3.49Å; I90-L93 VanDerWaalsContact O-N 3.16Å; I90-F94 HydrophobicContact CG2-CE2 3.97Å; I90-F94 VanDerWaalsContact O-CD2 3.28Å; I90-F94 WeakPolarHBondContact O-CD2 3.3Å
91	G	86	Confident	84.1	Confident	43 Å²	43	68.8 Å²	68.8	44%	0.443	36%	0.358	S	S	.	.	H	α-helix	trans	-61.2	-45.5	176.9	0	0	0	0	0	112.2	G88 L93 F94	G88-G91 PolarHBondContact O-N 3.31Å; G91-L93 PolarHBondContact O-N 3.12Å; G91-F94 PolarHBondContact O-N 2.62Å
92	G	91.5	Very high	85.6	Confident	3 Å²	3	67.4 Å²	67.4	3%	0.031	36%	0.357	C	S	.	.	H	α-helix	trans	-64.9	-24	175.8	0	0	0	0	0	113.8	S34 Y55 G88 I90 Y96	S34-G92 WeakPolarHBondContact CB-O 3.32Å; S34-G92 WeakPolarHBondContact OG-CA 3.3Å; S34-G92 PolarHBondContact OG-O 3.45Å; Y55-G92 VanDerWaalsContact OH-C 3.23Å; G88-G92 PolarHBondContact O-N 3.16Å; I90-G92 PolarHBondContact O-N 3.05Å; G92-Y96 VanDerWaalsContact O-CB 3.29Å; G92-Y96 WeakPolarHBondContact O-CB 3.1Å; G92-Y96 PolarHBondContact O-N 2.93Å
93	L	93.5	Very high	86.9	Confident	50 Å²	50	59.2 Å²	59.2	26%	0.262	33%	0.327	S	S	.	.	H	α-helix	trans	-66.9	-40.6	177.4	-179	70	0	0	0	110.8	F52 Y55 L89 I90 G91 Y96 V97	F52-L93 HydrophobicContact CD1-CD1 4.17Å; F52-L93 HydrophobicContact CE1-CD1 4.17Å; Y55-L93 HydrophobicContact CD1-CD1 3.45Å; Y55-L93 VanDerWaalsContact CD1-CD1 3.45Å; Y55-L93 HydrophobicContact CE1-CB 3.91Å; Y55-L93 HydrophobicContact CE1-CD1 3.56Å; Y55-L93 HydrophobicContact CE1-CG 4.33Å; Y55-L93 HydrophobicContact CG-CD1 3.98Å; Y55-L93 PolarHBondContact OH-N 3.49Å; L89-L93 PolarHBondContact O-N 3.22Å; I90-L93 WeakPolarHBondContact O-CB 3.48Å; I90-L93 PolarHBondContact O-N 3.49Å; I90-L93 VanDerWaalsContact O-N 3.16Å; G91-L93 PolarHBondContact O-N 3.12Å; L93-Y96 WeakPolarHBondContact O-CB 3.36Å; L93-Y96 PolarHBondContact O-N 3.13Å; L93-V97 HydrophobicContact CD1-CG2 4.28Å; L93-V97 HydrophobicContact CG-CG2 4.36Å; L93-V97 VanDerWaalsContact O-CG2 3.3Å; L93-V97 WeakPolarHBondContact O-CG2 3.28Å; L93-V97 PolarHBondContact O-N 3.45Å
94	F	94.2	Very high	88.1	Confident	147 Å²	147	60 Å²	60	65%	0.645	32%	0.324	S	S	*	.	H	α-helix	trans	-64.3	-45.8	178	-67.4	-68	0	0	0	111.8	I90 G91 Y96 V97 L98	I90-F94 HydrophobicContact CG2-CE2 3.97Å; I90-F94 VanDerWaalsContact O-CD2 3.28Å; I90-F94 WeakPolarHBondContact O-CD2 3.3Å; G91-F94 PolarHBondContact O-N 2.62Å; F94-Y96 VanDerWaalsContact C-N 3.3Å; F94-Y96 PolarHBondContact O-N 3.4Å; F94-V97 PolarHBondContact O-N 3.36Å; F94-L98 WeakPolarHBondContact O-CB 3.47Å; F94-L98 PolarHBondContact O-N 2.93Å
95	T	95.3	Very high	89.3	Confident	36 Å²	36	60.6 Å²	60.6	22%	0.221	33%	0.33	C	S	.	.	H	α-helix	trans	-59.8	-43.4	174.3	-53	0	0	0	0	111.1	T31 A35 L98 F99	T31-T95 HydrophobicContact CG2-CG2 4.27Å; A35-T95 HydrophobicContact CB-CG2 3.93Å; T95-L98 PolarHBondContact O-N 3.36Å; T95-F99 HydrophobicContact CG2-CD2 3.99Å; T95-F99 HydrophobicContact CG2-CE2 4Å; T95-F99 WeakPolarHBondContact O-CD2 3.14Å; T95-F99 PolarHBondContact O-N 3.38Å
96	Y	96.5	Very high	90.7	Very high	0 Å²	0	60.8 Å²	60.8	0%	0	33%	0.334	C	S	.	.	H	α-helix	trans	-58.9	-53.2	176.5	172.3	-92.7	0	0	0	112.4	S34 A41 G51 F54 Y55 G92 L93 F94 L98 F99 W100	S34-Y96 WeakPolarHBondContact O-CA 3.33Å; A41-Y96 HydrophobicContact CB-CE2 4.13Å; A41-Y96 WeakPolarHBondContact CB-OH 3.14Å; G51-Y96 PolarHBondContact O-OH 3.35Å; F54-Y96 HydrophobicContact CD1-CE2 4.23Å; Y55-Y96 AromaticContact CD2-CD1 3.87Å; Y55-Y96 HydrophobicContact CD2-CD1 3.87Å; Y55-Y96 AromaticContact CD2-CD2 3.53Å; Y55-Y96 HydrophobicContact CD2-CD2 3.53Å; Y55-Y96 HydrophobicContact CD2-CE1 4.45Å; Y55-Y96 HydrophobicContact CD2-CE2 4.14Å; Y55-Y96 AromaticContact CD2-CG 3.38Å; Y55-Y96 HydrophobicContact CD2-CG 3.38Å; Y55-Y96 HydrophobicContact CE2-CD2 4.38Å; Y55-Y96 HydrophobicContact CE2-CG 4.07Å; Y55-Y96 HydrophobicContact CG-CD1 4.03Å; Y55-Y96 HydrophobicContact CG-CD2 4.29Å; Y55-Y96 HydrophobicContact CG-CE1 4.33Å; Y55-Y96 HydrophobicContact CG-CG 4.02Å; G92-Y96 VanDerWaalsContact O-CB 3.29Å; G92-Y96 WeakPolarHBondContact O-CB 3.1Å; G92-Y96 PolarHBondContact O-N 2.93Å; L93-Y96 WeakPolarHBondContact O-CB 3.36Å; L93-Y96 PolarHBondContact O-N 3.13Å; F94-Y96 VanDerWaalsContact C-N 3.3Å; F94-Y96 PolarHBondContact O-N 3.4Å; Y96-L98 VanDerWaalsContact C-N 3.27Å; Y96-L98 PolarHBondContact O-N 3.37Å; Y96-F99 PolarHBondContact O-N 3.34Å; Y96-W100 HydrophobicContact CD1-CE3 4.16Å; Y96-W100 HydrophobicContact CE1-CB 4.21Å; Y96-W100 AromaticContact CE1-CD2 3.95Å; Y96-W100 HydrophobicContact CE1-CD2 3.95Å; Y96-W100 AromaticContact CE1-CE3 3.48Å; Y96-W100 HydrophobicContact CE1-CE3 3.48Å; Y96-W100 VanDerWaalsContact CE1-CE3 3.48Å; Y96-W100 HydrophobicContact CE1-CG 4.27Å; Y96-W100 HydrophobicContact CE1-CZ3 4.18Å; Y96-W100 WeakPolarHBondContact O-CB 3.38Å; Y96-W100 PolarHBondContact O-N 3.33Å
97	V	96.1	Very high	91.7	Very high	46 Å²	46	59.4 Å²	59.4	28%	0.279	33%	0.325	S	S	.	.	H	α-helix	trans	-61.4	-38.1	-177.7	172.2	0	0	0	0	111.1	F52 L93 F94 W100 T101	F52-V97 HydrophobicContact CE1-CG2 4.12Å; L93-V97 HydrophobicContact CD1-CG2 4.28Å; L93-V97 HydrophobicContact CG-CG2 4.36Å; L93-V97 VanDerWaalsContact O-CG2 3.3Å; L93-V97 WeakPolarHBondContact O-CG2 3.28Å; L93-V97 PolarHBondContact O-N 3.45Å; F94-V97 PolarHBondContact O-N 3.36Å; V97-W100 HydrophobicContact CG2-CE3 4.36Å; V97-T101 HydrophobicContact CG1-CG2 4.26Å; V97-T101 WeakPolarHBondContact O-CB 3.06Å; V97-T101 WeakPolarHBondContact O-CG2 3.23Å; V97-T101 PolarHBondContact O-N 2.97Å; V97-T101 PolarHBondContact O-OG1 3Å
98	L	95.6	Very high	92.6	Very high	104 Å²	104	63.1 Å²	63.1	55%	0.545	34%	0.338	S	S	.	.	H	α-helix	trans	-57.9	-57.7	175.1	-171.5	166.7	0	0	0	110.7	F94 T95 Y96 W100 T101 F102	F94-L98 WeakPolarHBondContact O-CB 3.47Å; F94-L98 PolarHBondContact O-N 2.93Å; T95-L98 PolarHBondContact O-N 3.36Å; Y96-L98 VanDerWaalsContact C-N 3.27Å; Y96-L98 PolarHBondContact O-N 3.37Å; L98-W100 VanDerWaalsContact C-N 3.34Å; L98-W100 PolarHBondContact O-N 3.08Å; L98-T101 PolarHBondContact O-OG1 3.02Å; L98-F102 WeakPolarHBondContact O-CB 3.46Å; L98-F102 PolarHBondContact O-N 3.44Å
99	F	97.2	Very high	93.2	Very high	76 Å²	76	66.2 Å²	66.2	33%	0.333	35%	0.349	S	S	.	.	H	α-helix	trans	-67.3	-34.8	-178.6	-80.3	-77.7	0	0	0	113	A35 T95 Y96 L103	A35-F99 HydrophobicContact CB-CD2 3.61Å; A35-F99 HydrophobicContact CB-CE2 3.56Å; A35-F99 HydrophobicContact CB-CG 4.35Å; A35-F99 HydrophobicContact CB-CZ 4.26Å; T95-F99 HydrophobicContact CG2-CD2 3.99Å; T95-F99 HydrophobicContact CG2-CE2 4Å; T95-F99 WeakPolarHBondContact O-CD2 3.14Å; T95-F99 PolarHBondContact O-N 3.38Å; Y96-F99 PolarHBondContact O-N 3.34Å; F99-L103 WeakPolarHBondContact O-CB 3.43Å; F99-L103 PolarHBondContact O-N 2.76Å
100	W	96.9	Very high	93.3	Very high	20 Å²	20	74.9 Å²	74.9	8%	0.076	38%	0.38	C	S	.	.	H	α-helix	trans	-60.9	-56.5	177.4	172.4	26.7	0	0	0	111.6	G38 A41 G42 L46 G48 F52 Y96 V97 L98 Y104	G38-W100 WeakPolarHBondContact O-CA 3.48Å; A41-W100 HydrophobicContact CB-CG 4.25Å; G42-W100 VanDerWaalsContact CA-O 3.3Å; G42-W100 WeakPolarHBondContact CA-O 3.36Å; L46-W100 VanDerWaalsContact O-CE2 3.27Å; L46-W100 VanDerWaalsContact O-CZ2 3.24Å; L46-W100 WeakPolarHBondContact O-CZ2 3.03Å; L46-W100 PolarHBondContact O-NE1 2.99Å; G48-W100 WeakPolarHBondContact O-CH2 3.49Å; F52-W100 HydrophobicContact CD1-CZ3 4.44Å; F52-W100 HydrophobicContact CD2-CH2 4.14Å; F52-W100 HydrophobicContact CD2-CZ3 4.14Å; F52-W100 HydrophobicContact CE1-CZ3 4.21Å; F52-W100 HydrophobicContact CE2-CH2 4.07Å; F52-W100 AromaticContact CE2-CZ3 3.9Å; F52-W100 HydrophobicContact CE2-CZ3 3.9Å; F52-W100 HydrophobicContact CG-CZ3 4.41Å; F52-W100 AromaticContact CZ-CZ3 3.94Å; F52-W100 HydrophobicContact CZ-CZ3 3.94Å; Y96-W100 HydrophobicContact CD1-CE3 4.16Å; Y96-W100 HydrophobicContact CE1-CB 4.21Å; Y96-W100 AromaticContact CE1-CD2 3.95Å; Y96-W100 HydrophobicContact CE1-CD2 3.95Å; Y96-W100 AromaticContact CE1-CE3 3.48Å; Y96-W100 HydrophobicContact CE1-CE3 3.48Å; Y96-W100 VanDerWaalsContact CE1-CE3 3.48Å; Y96-W100 HydrophobicContact CE1-CG 4.27Å; Y96-W100 HydrophobicContact CE1-CZ3 4.18Å; Y96-W100 WeakPolarHBondContact O-CB 3.38Å; Y96-W100 PolarHBondContact O-N 3.33Å; V97-W100 HydrophobicContact CG2-CE3 4.36Å; L98-W100 VanDerWaalsContact C-N 3.34Å; L98-W100 PolarHBondContact O-N 3.08Å; W100-Y104 WeakPolarHBondContact O-CB 3.33Å; W100-Y104 PolarHBondContact O-N 3.03Å
101	T	95.4	Very high	93.6	Very high	78 Å²	78	72.2 Å²	72.2	48%	0.479	37%	0.366	S	S	.	.	H	α-helix	trans	-69.7	-37.6	-178.2	55.7	0	0	0	0	112.3	V97 L98 G105	V97-T101 HydrophobicContact CG1-CG2 4.26Å; V97-T101 WeakPolarHBondContact O-CB 3.06Å; V97-T101 WeakPolarHBondContact O-CG2 3.23Å; V97-T101 PolarHBondContact O-N 2.97Å; V97-T101 PolarHBondContact O-OG1 3Å; L98-T101 PolarHBondContact O-OG1 3.02Å; T101-G105 PolarHBondContact O-N 3.38Å
102	F	95.7	Very high	94	Very high	130 Å²	130	73.7 Å²	73.7	57%	0.57	36%	0.361	S	S	*	.	H	α-helix	trans	-60.7	-52	177.4	177.4	-108.2	0	0	0	111.9	L98 G105 M106	L98-F102 WeakPolarHBondContact O-CB 3.46Å; L98-F102 PolarHBondContact O-N 3.44Å; F102-G105 PolarHBondContact O-N 3.34Å; F102-M106 PolarHBondContact O-N 2.76Å
103	L	96.1	Very high	94.2	Very high	24 Å²	24	77.6 Å²	77.6	13%	0.126	38%	0.38	C	S	.	.	H	α-helix	trans	-75.2	-30.4	-179.7	-76.6	167.1	0	0	0	112.8	A39 F99 G105 M106 V107	A39-L103 HydrophobicContact CB-CD1 3.24Å; F99-L103 WeakPolarHBondContact O-CB 3.43Å; F99-L103 PolarHBondContact O-N 2.76Å; L103-G105 VanDerWaalsContact C-N 3.33Å; L103-M106 HydrophobicContact CD2-CE 3.32Å; L103-M106 HydrophobicContact CD2-SD 4.15Å; L103-M106 PolarHBondContact O-N 3.43Å; L103-V107 WeakPolarHBondContact O-CB 3.24Å; L103-V107 WeakPolarHBondContact O-CG2 3.38Å; L103-V107 PolarHBondContact O-N 3.42Å
104	Y	95.8	Very high	94.2	Very high	73 Å²	73	79.2 Å²	79.2	29%	0.286	39%	0.387	S	S	.	.	H	α-helix	trans	-58.6	-48.4	169.5	-177.2	-83.8	0	0	0	110.8	G42 T47 W100 M106 V107 H108 V109	G42-Y104 WeakPolarHBondContact O-CA 3.42Å; T47-Y104 HydrophobicContact CG2-CD2 4.44Å; T47-Y104 HydrophobicContact CG2-CE2 3.47Å; T47-Y104 VanDerWaalsContact CG2-CE2 3.47Å; T47-Y104 WeakPolarHBondContact CG2-OH 3.38Å; W100-Y104 WeakPolarHBondContact O-CB 3.33Å; W100-Y104 PolarHBondContact O-N 3.03Å; Y104-M106 VanDerWaalsContact C-N 3.31Å; Y104-M106 PolarHBondContact O-N 3.03Å; Y104-V107 PolarHBondContact O-N 3.29Å; Y104-H108 HydrophobicContact CD1-CB 4.49Å; Y104-H108 AromaticContact CD2-CD2 3.84Å; Y104-H108 HydrophobicContact CE1-CB 4.18Å; Y104-H108 HydrophobicContact CE2-CB 4.35Å; Y104-H108 AromaticContact CE2-CD2 4Å; Y104-H108 WeakPolarHBondContact O-CB 3.38Å; Y104-H108 PolarHBondContact O-N 3.09Å; Y104-V109 HydrophobicContact CE1-CG2 4.39Å
105	G	95.2	Very high	94.2	Very high	14 Å²	14	75 Å²	75	14%	0.144	37%	0.371	C	S	.	.	I	π-helix	trans	-58.3	-43.7	175.5	0	0	0	0	0	112	T101 F102 L103 V107 V109 Y110	T101-G105 PolarHBondContact O-N 3.38Å; F102-G105 PolarHBondContact O-N 3.34Å; L103-G105 VanDerWaalsContact C-N 3.33Å; G105-V107 PolarHBondContact O-N 3.38Å; G105-V109 WeakPolarHBondContact O-CA 3.5Å; G105-V109 VanDerWaalsContact O-CB 3.25Å; G105-V109 WeakPolarHBondContact O-CB 3.41Å; G105-V109 PolarHBondContact O-N 2.91Å; G105-V109 VanDerWaalsContact O-N 3.15Å; G105-Y110 VanDerWaalsContact O-CD2 3.23Å; G105-Y110 WeakPolarHBondContact O-CD2 3.23Å; G105-Y110 PolarHBondContact O-N 2.92Å; G105-Y110 VanDerWaalsContact O-N 3.09Å
106	M	94.3	Very high	94.1	Very high	103 Å²	103	77.6 Å²	77.6	51%	0.507	38%	0.381	S	S	.	.	I	π-helix	trans	-68	-30.9	-178.9	-167.7	179.7	82.1	0	0	114.7	F102 L103 Y104	F102-M106 PolarHBondContact O-N 2.76Å; L103-M106 HydrophobicContact CD2-CE 3.32Å; L103-M106 HydrophobicContact CD2-SD 4.15Å; L103-M106 PolarHBondContact O-N 3.43Å; Y104-M106 VanDerWaalsContact C-N 3.31Å; Y104-M106 PolarHBondContact O-N 3.03Å
107	V	94.5	Very high	94	Very high	64 Å²	64	83.1 Å²	83.1	39%	0.388	41%	0.408	S	S	.	.	I	π-helix	trans	-99.6	-33.3	-173.8	175.7	0	0	0	0	112.6	I43 L103 Y104 G105	I43-V107 HydrophobicContact CG1-CG2 4.47Å; L103-V107 WeakPolarHBondContact O-CB 3.24Å; L103-V107 WeakPolarHBondContact O-CG2 3.38Å; L103-V107 PolarHBondContact O-N 3.42Å; Y104-V107 PolarHBondContact O-N 3.29Å; G105-V107 PolarHBondContact O-N 3.38Å
108	H	91	Very high	93.8	Very high	94 Å²	94	86 Å²	86	44%	0.435	42%	0.418	S	S	.	.	I	π-helix	trans	-112.3	-16.4	-171.3	-63.7	-77.9	0	0	0	113.8	I43 G45 Y104	I43-H108 PolarHBondContact O-NE2 3.46Å; G45-H108 WeakPolarHBondContact CA-NE2 3.25Å; G45-H108 PolarHBondContact N-NE2 3.15Å; Y104-H108 HydrophobicContact CD1-CB 4.49Å; Y104-H108 AromaticContact CD2-CD2 3.84Å; Y104-H108 HydrophobicContact CE1-CB 4.18Å; Y104-H108 HydrophobicContact CE2-CB 4.35Å; Y104-H108 AromaticContact CE2-CD2 4Å; Y104-H108 WeakPolarHBondContact O-CB 3.38Å; Y104-H108 PolarHBondContact O-N 3.09Å
109	V	88.5	Confident	93.7	Very high	101 Å²	101	84.5 Å²	84.5	61%	0.612	41%	0.407	S	S	*	.	I	π-helix	trans	-105.2	-45.9	178.9	-177.5	0	0	0	0	111.6	Y104 G105	Y104-V109 HydrophobicContact CE1-CG2 4.39Å; G105-V109 WeakPolarHBondContact O-CA 3.5Å; G105-V109 VanDerWaalsContact O-CB 3.25Å; G105-V109 WeakPolarHBondContact O-CB 3.41Å; G105-V109 PolarHBondContact O-N 2.91Å; G105-V109 VanDerWaalsContact O-N 3.15Å
110	Y	83.5	Confident	93.3	Very high	237 Å²	237	85.3 Å²	85.3	93%	0.929	41%	0.414	S	S	*	.			trans	-94.7	0	175.3	-59.4	-67.8	0	0	0	111.1	G105	G105-Y110 VanDerWaalsContact O-CD2 3.23Å; G105-Y110 WeakPolarHBondContact O-CD2 3.23Å; G105-Y110 PolarHBondContact O-N 2.92Å; G105-Y110 VanDerWaalsContact O-N 3.09Å

Retrieved 110 of 110 residues in 281.4 ms (Link to these results)

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