TM39B_HUMAN Loading...

Transmembrane protein 39B

May protect the cells against DNA damage caused by exposure to the cold-warming stress and facilitates tissue damage repair during the recovery phase.

AlphaFold DB , UniProt , Accession Q9GZU3, Species HUMAN (Homo sapiens, Human), Gene TMEM39B, Length 492 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	35.1	Very low	33.3	Very low	246 Å²	246	155.9 Å²	155.9	100%	1.212	86%	0.856	S	S	*	*				0	93.6	0	-73.2	-77.4	-173.3	0	0	108.1	G3	M1-G3 PolarHBondContact O-N 3.28Å
2	G	35.2	Very low	32.9	Very low	84 Å²	84	159.8 Å²	159.8	87%	0.866	85%	0.851	S	S	*	*			trans	-74.3	111.1	-171.5	0	0	0	0	0	112.6	R4	G2-R4 PolarHBondContact O-N 3.46Å
3	G	35.8	Very low	32.4	Very low	72 Å²	72	157.7 Å²	157.7	74%	0.742	85%	0.854	S	S	*	*			trans	-75.7	108.7	175.5	0	0	0	0	0	111.7	M1 R5	M1-G3 PolarHBondContact O-N 3.28Å; G3-R5 PolarHBondContact O-N 3.07Å
4	R	37.5	Very low	31.9	Very low	249 Å²	249	163.4 Å²	163.4	94%	0.94	86%	0.857	S	S	*	*			trans	-62	110.2	169.7	-80.8	-178.1	172.2	-164.5	-2.2	109.7	G2 G6	G2-R4 PolarHBondContact O-N 3.46Å; R4-G6 PolarHBondContact O-N 3.13Å
5	R	39.5	Very low	31.5	Very low	249 Å²	249	162.7 Å²	162.7	94%	0.94	85%	0.854	S	S	*	*	P	Polyproline II helix	trans	-74.2	117.9	167.8	-73	-177.3	176	-168.4	-1.2	109	G3	G3-R5 PolarHBondContact O-N 3.07Å
6	G	33.2	Very low	31.7	Very low	65 Å²	65	159.5 Å²	159.5	67%	0.67	85%	0.847	S	S	*	*	P	Polyproline II helix	trans	-68.3	158.4	174.1	0	0	0	0	0	112.7	R4	R4-G6 PolarHBondContact O-N 3.13Å
7	P	36.2	Very low	31.7	Very low	135 Å²	135	158.1 Å²	158.1	88%	0.877	84%	0.839	S	S	*	*	P	Polyproline II helix	trans	-75.3	147.2	-167.2	30	-33.7	0	0	0	113.3
8	N	32.1	Very low	31.2	Very low	154 Å²	154	156.2 Å²	156.2	82%	0.824	84%	0.839	S	S	*	*			trans	-45.5	127.3	-173.2	-123.8	-13.9	0	0	0	114.7	T10	N8-T10 PolarHBondContact O-N 3.4Å
9	R	27.1	Very low	31.1	Very low	247 Å²	247	156.5 Å²	156.5	93%	0.932	83%	0.834	S	S	*	*			trans	-68.9	102.2	163.4	-90.5	-179	172.7	175.9	-2	108.7
10	T	29.4	Very low	31.1	Very low	98 Å²	98	155.1 Å²	155.1	60%	0.601	83%	0.834	S	S	*	*			trans	-83.1	115.6	161.6	37.2	0	0	0	0	109	N8 Y12	N8-T10 PolarHBondContact O-N 3.4Å; T10-Y12 WeakPolarHBondContact O-CD2 2.92Å; T10-Y12 PolarHBondContact O-N 2.88Å
11	S	24.9	Very low	30.7	Very low	116 Å²	116	151.4 Å²	151.4	81%	0.811	83%	0.833	S	S	*	*			trans	-71.6	114.8	176	57.2	0	0	0	0	109.9
12	Y	29	Very low	30.5	Very low	202 Å²	202	145.3 Å²	145.3	79%	0.792	81%	0.814	S	S	*	*	P	Polyproline II helix	trans	-99.6	136.2	171.3	-73	-79.7	0	0	0	111	T10	T10-Y12 WeakPolarHBondContact O-CD2 2.92Å; T10-Y12 PolarHBondContact O-N 2.88Å
13	C	26.9	Very low	30.2	Very low	133 Å²	133	147.5 Å²	147.5	90%	0.899	82%	0.816	S	S	*	*	P	Polyproline II helix	trans	-57.4	139.4	-173.9	-64.9	0	0	0	0	113.3
14	R	24.5	Very low	29.8	Very low	237 Å²	237	147.5 Å²	147.5	89%	0.894	82%	0.817	S	S	*	*	P	Polyproline II helix	trans	-93.9	119.1	-175.4	-162.6	-173.3	-127.1	168.6	-0.8	108.8
15	N	26.8	Very low	29.4	Very low	153 Å²	153	139.4 Å²	139.4	82%	0.818	81%	0.811	S	S	*	*	P	Polyproline II helix	trans	-101.2	152.4	164.1	-101.2	43	0	0	0	110.4
16	P	34.8	Very low	28.7	Very low	112 Å²	112	132.8 Å²	132.8	73%	0.727	80%	0.803	S	S	*	*	P	Polyproline II helix	trans	-92	129.8	-148.3	20.7	-9.9	0	0	0	115.3
17	L	30.4	Very low	28.3	Very low	136 Å²	136	135.8 Å²	135.8	71%	0.712	81%	0.813	S	S	*	*			trans	11.6	113.8	142.7	-71.7	136	0	0	0	118.8	E19	L17-E19 HydrophobicContact CB-CG 4.49Å; L17-E19 HydrophobicContact CD2-CG 4.12Å; L17-E19 PolarHBondContact O-N 3.43Å
18	C	23.8	Very low	27.9	Very low	124 Å²	124	133.4 Å²	133.4	84%	0.838	81%	0.813	S	S	*	*			trans	-77.3	96.4	144.1	-80.2	0	0	0	0	108.4
19	E	29.4	Very low	27.5	Very low	161 Å²	161	130.8 Å²	130.8	75%	0.752	81%	0.807	S	S	*	*			trans	-90.6	128.6	160.1	-78.7	-164.8	157.7	0	0	109.5	L17 G21	L17-E19 HydrophobicContact CB-CG 4.49Å; L17-E19 HydrophobicContact CD2-CG 4.12Å; L17-E19 PolarHBondContact O-N 3.43Å; E19-G21 PolarHBondContact O-N 3Å
20	P	30.3	Very low	27.4	Very low	128 Å²	128	127.4 Å²	127.4	83%	0.831	80%	0.801	S	S	*	*			trans	-75.4	112.4	171.9	28.8	-28.7	0	0	0	109.6
21	G	23.2	Very low	27.2	Very low	79 Å²	79	128.4 Å²	128.4	81%	0.814	81%	0.808	S	S	*	*			trans	21.9	113.6	158.2	0	0	0	0	0	119.7	E19	E19-G21 PolarHBondContact O-N 3Å
22	S	30.1	Very low	27.2	Very low	117 Å²	117	127.7 Å²	127.7	82%	0.818	80%	0.803	S	S	*	*			trans	-137.2	98.9	144.4	56.9	0	0	0	0	109.3	G24	S22-G24 VanDerWaalsContact C-N 3.34Å; S22-G24 PolarHBondContact O-N 3.19Å
23	S	29.8	Very low	27	Very low	130 Å²	130	123.5 Å²	123.5	91%	0.909	80%	0.803	S	S	*	*			trans	-62.2	89.6	167	27.8	0	0	0	0	109.9	G25	S23-G25 PolarHBondContact O-N 3.08Å
24	G	26.3	Very low	27	Very low	73 Å²	73	121.5 Å²	121.5	75%	0.753	80%	0.796	S	S	*	*			trans	-89.7	81.8	171.2	0	0	0	0	0	110.8	S22 S26	S22-G24 VanDerWaalsContact C-N 3.34Å; S22-G24 PolarHBondContact O-N 3.19Å; G24-S26 PolarHBondContact O-N 3.02Å
25	G	28.8	Very low	27.1	Very low	79 Å²	79	115.1 Å²	115.1	81%	0.814	79%	0.788	S	S	*	*			trans	-73	116.1	165.6	0	0	0	0	0	109.9	S23	S23-G25 PolarHBondContact O-N 3.08Å
26	S	25.1	Very low	27.2	Very low	110 Å²	110	113.9 Å²	113.9	77%	0.769	79%	0.785	S	S	*	*			trans	-68.6	159.1	175	-66.8	0	0	0	0	113.1	G24	G24-S26 PolarHBondContact O-N 3.02Å
27	S	25.6	Very low	27	Very low	128 Å²	128	114.5 Å²	114.5	90%	0.895	79%	0.787	S	S	*	*			trans	86.3	117.6	158.4	71.5	0	0	0	0	118.1
28	G	27.6	Very low	26.8	Very low	84 Å²	84	113 Å²	113	87%	0.866	79%	0.788	S	S	*	*			trans	150.1	52.7	170	0	0	0	0	0	114.8
29	S	23.2	Very low	27.3	Very low	100 Å²	100	113.2 Å²	113.2	70%	0.699	79%	0.785	S	S	*	*			trans	-85.2	121.2	167.2	67.2	0	0	0	0	109.2
30	H	25.8	Very low	27.1	Very low	175 Å²	175	117.6 Å²	117.6	81%	0.81	80%	0.795	S	S	*	*			trans	-168.7	129.4	141.9	-87.4	-53.8	0	0	0	111.2
31	T	24.8	Very low	27.2	Very low	120 Å²	120	115.7 Å²	115.7	74%	0.736	79%	0.785	S	S	*	*			trans	70.1	109	144.1	59.1	0	0	0	0	121.5
32	S	24.7	Very low	27.4	Very low	101 Å²	101	124 Å²	124	71%	0.706	79%	0.791	S	S	*	*				85.4	118	116.5	-52.2	0	0	0	0	121.4
33	S	24.6	Very low	27.5	Very low	113 Å²	113	124.2 Å²	124.2	79%	0.79	79%	0.788	S	S	*	*			trans	91	127.9	132.9	72.1	0	0	0	0	120.5
34	A	27.7	Very low	27.5	Very low	92 Å²	92	129.3 Å²	129.3	76%	0.76	79%	0.787	S	S	*	*			trans	68.6	143	151.5	0	0	0	0	0	116.3
35	S	26.2	Very low	27.5	Very low	103 Å²	103	131.7 Å²	131.7	72%	0.72	79%	0.792	S	S	*	*			cis	-175.2	146.6	9.8	14.4	0	0	0	0	107.7
36	V	28.5	Very low	27.7	Very low	127 Å²	127	132.8 Å²	132.8	77%	0.77	79%	0.787	S	S	*	*			trans	81.4	138.2	138.1	179.9	0	0	0	0	120.7
37	T	30.4	Very low	28	Very low	125 Å²	125	133.6 Å²	133.6	77%	0.767	79%	0.793	S	S	*	*			trans	87.1	96.9	159.1	32.9	0	0	0	0	121
38	S	27.1	Very low	28.3	Very low	105 Å²	105	130.4 Å²	130.4	73%	0.734	78%	0.781	S	S	*	*				46.3	110.1	114.4	174.3	0	0	0	0	118.2
39	V	34.2	Very low	28.6	Very low	128 Å²	128	132.7 Å²	132.7	78%	0.776	78%	0.778	S	S	*	*				-155.2	118.9	110.9	176.3	0	0	0	0	108.1	S41	V39-S41 PolarHBondContact O-N 3.1Å
40	R	24.7	Very low	29	Very low	252 Å²	252	131.1 Å²	131.1	95%	0.951	78%	0.778	S	S	*	*			trans	-78.8	101.9	174.8	-135.3	173.6	-171.8	152.4	-0.4	107.8
41	S	31.9	Very low	29.4	Very low	88 Å²	88	130.4 Å²	130.4	62%	0.615	78%	0.779	S	S	*	*			trans	-120.8	115.9	161.6	56.9	0	0	0	0	108.7	V39 T43	V39-S41 PolarHBondContact O-N 3.1Å; S41-T43 VanDerWaalsContact C-N 3.33Å; S41-T43 PolarHBondContact O-N 3Å
42	R	27.9	Very low	29.8	Very low	254 Å²	254	130.1 Å²	130.1	96%	0.958	78%	0.782	S	S	*	*			trans	-69	87.5	177.1	-76	173.5	167.5	155.2	-5.4	108.5	R44	R42-R44 PolarHBondContact O-N 3.36Å
43	T	31.7	Very low	30.1	Very low	122 Å²	122	129.5 Å²	129.5	75%	0.748	78%	0.777	S	S	*	*			trans	-84.9	106.6	163.3	41.4	0	0	0	0	108.3	S41 S45	S41-T43 VanDerWaalsContact C-N 3.33Å; S41-T43 PolarHBondContact O-N 3Å; T43-S45 PolarHBondContact O-N 3.04Å; T43-S45 VanDerWaalsContact O-N 3.16Å
44	R	30.5	Very low	30.6	Very low	237 Å²	237	128.6 Å²	128.6	89%	0.894	77%	0.769	S	S	*	*			trans	-58.2	114.7	173.3	-161	176.1	-167.2	169.8	2	107.8	R42 S46	R42-R44 PolarHBondContact O-N 3.36Å; R44-S46 VanDerWaalsContact C-N 3.28Å; R44-S46 PolarHBondContact O-N 2.76Å
45	S	26.3	Very low	31.3	Very low	122 Å²	122	128 Å²	128	85%	0.853	76%	0.757	S	S	*	*			trans	-61.8	87.7	171.1	-30.4	0	0	0	0	108.9	T43	T43-S45 PolarHBondContact O-N 3.04Å; T43-S45 VanDerWaalsContact O-N 3.16Å
46	S	33	Very low	32.1	Very low	102 Å²	102	127.9 Å²	127.9	71%	0.713	75%	0.748	S	S	*	*			trans	-104.3	96.8	157.7	60.8	0	0	0	0	107.1	R44 G48	R44-S46 VanDerWaalsContact C-N 3.28Å; R44-S46 PolarHBondContact O-N 2.76Å; S46-G48 PolarHBondContact O-N 3.28Å
47	S	31.5	Very low	33.1	Very low	128 Å²	128	123.9 Å²	123.9	90%	0.895	73%	0.728	S	S	*	*			trans	-51.1	75.1	153.4	47.8	0	0	0	0	109.9
48	G	32.4	Very low	33.8	Very low	61 Å²	61	122.9 Å²	122.9	63%	0.629	72%	0.722	S	S	*	*			trans	-103.8	100.8	162.5	0	0	0	0	0	105.4	S46 G50	S46-G48 PolarHBondContact O-N 3.28Å; G48-G50 PolarHBondContact O-N 2.83Å
49	T	34.6	Very low	34.7	Very low	132 Å²	132	123.7 Å²	123.7	81%	0.81	71%	0.714	S	S	*	*			trans	-54.1	87.8	163.9	44.7	0	0	0	0	107.7	L51	T49-L51 PolarHBondContact O-N 2.85Å
50	G	30.9	Very low	35.5	Very low	67 Å²	67	123.4 Å²	123.4	69%	0.691	71%	0.713	S	S	*	*			trans	-60.5	94.6	161.4	0	0	0	0	0	104.7	G48 S52	G48-G50 PolarHBondContact O-N 2.83Å; G50-S52 PolarHBondContact O-N 3.19Å
51	L	34.8	Very low	37	Very low	160 Å²	160	114.3 Å²	114.3	84%	0.838	69%	0.685	S	S	*	*			trans	-51.4	97.8	161	-75.5	139.3	0	0	0	104.5	T49 S53	T49-L51 PolarHBondContact O-N 2.85Å; L51-S53 PolarHBondContact O-N 3.26Å
52	S	33.2	Very low	38.2	Very low	114 Å²	114	114.6 Å²	114.6	80%	0.797	68%	0.683	S	S	*	*			trans	-57.4	91	158.1	-70.1	0	0	0	0	104	G50 P54	G50-S52 PolarHBondContact O-N 3.19Å; S52-P54 WeakPolarHBondContact O-CD 3.45Å
53	S	29.2	Very low	39.9	Very low	87 Å²	87	107 Å²	107	61%	0.608	67%	0.667	S	S	*	*	P	Polyproline II helix	trans	-49.2	118.3	172.8	43.6	0	0	0	0	105.4	L51	L51-S53 PolarHBondContact O-N 3.26Å
54	P	35.8	Very low	41.3	Very low	94 Å²	94	103 Å²	103	61%	0.61	64%	0.641	S	S	*	*	P	Polyproline II helix	trans	-55.2	136.8	179.6	22.2	-30.7	0	0	0	106.9	S52 L56	S52-P54 WeakPolarHBondContact O-CD 3.45Å; P54-L56 PolarHBondContact O-N 2.99Å; P54-L56 VanDerWaalsContact O-N 3.11Å
55	P	43.5	Very low	42.7	Very low	81 Å²	81	101 Å²	101	53%	0.526	64%	0.641	S	S	.	*	P	Polyproline II helix	trans	-55.1	127.4	-173.3	22.4	-32.1	0	0	0	108	A57 T58	P55-A57 HydrophobicContact CB-CB 4.39Å; P55-A57 PolarHBondContact O-N 2.96Å; P55-T58 PolarHBondContact O-N 3.33Å; P55-T58 PolarHBondContact O-OG1 2.92Å
56	L	42.9	Very low	44.8	Very low	100 Å²	100	98 Å²	98	52%	0.524	61%	0.614	S	S	.	*	G	3₁₀ helix	trans	-51.9	-15.1	178.2	-108.9	81.3	0	0	0	112.9	P54 T58 Q59	P54-L56 PolarHBondContact O-N 2.99Å; P54-L56 VanDerWaalsContact O-N 3.11Å; L56-T58 PolarHBondContact O-N 3.45Å; L56-T58 VanDerWaalsContact O-N 3.11Å; L56-Q59 WeakPolarHBondContact O-CG 3.47Å; L56-Q59 PolarHBondContact O-N 3.35Å; L56-Q59 VanDerWaalsContact O-N 3.13Å
57	A	48	Very low	46.4	Very low	43 Å²	43	94.2 Å²	94.2	36%	0.355	59%	0.587	S	S	.	*	G	3₁₀ helix	trans	-56.3	-14.3	168.1	0	0	0	0	0	114.7	P55	P55-A57 HydrophobicContact CB-CB 4.39Å; P55-A57 PolarHBondContact O-N 2.96Å
58	T	45.5	Very low	47.9	Very low	103 Å²	103	97.7 Å²	97.7	63%	0.632	59%	0.586	S	S	*	*	G	3₁₀ helix	trans	-90.8	2	176.3	51.3	0	0	0	0	114.3	P55 L56 T60	P55-T58 PolarHBondContact O-N 3.33Å; P55-T58 PolarHBondContact O-OG1 2.92Å; L56-T58 PolarHBondContact O-N 3.45Å; L56-T58 VanDerWaalsContact O-N 3.11Å; T58-T60 PolarHBondContact O-N 3.42Å
59	Q	47.1	Very low	49.5	Very low	123 Å²	123	96.3 Å²	96.3	58%	0.575	56%	0.564	S	S	*	*	S	Bend	trans	-58	126.9	167.8	-73.4	-174.8	7	0	0	108.8	L56 V61	L56-Q59 WeakPolarHBondContact O-CG 3.47Å; L56-Q59 PolarHBondContact O-N 3.35Å; L56-Q59 VanDerWaalsContact O-N 3.13Å; Q59-V61 PolarHBondContact O-N 3.24Å
60	T	50.3	Low	50.7	Low	121 Å²	121	93.7 Å²	93.7	74%	0.742	55%	0.549	S	S	*	.			trans	-41.5	115.7	178.1	48.4	0	0	0	0	109.8	T58 V62	T58-T60 PolarHBondContact O-N 3.42Å; T60-V62 VanDerWaalsContact C-N 3.31Å; T60-V62 PolarHBondContact O-N 2.81Å
61	V	55.4	Low	52	Low	61 Å²	61	99.7 Å²	99.7	37%	0.37	56%	0.559	S	S	.	*			trans	-64.6	96.7	176.5	-173	0	0	0	0	107.1	Q59 P63 L266 M378 Y398	Q59-V61 PolarHBondContact O-N 3.24Å; V61-P63 VanDerWaalsContact O-CD 3.32Å; V61-P63 WeakPolarHBondContact O-CD 3.31Å; V61-L266 HydrophobicContact CB-CD2 3.89Å; V61-L266 HydrophobicContact CG1-CD2 3.27Å; V61-M378 HydrophobicContact CG1-SD 3.85Å; V61-Y398 HydrophobicContact CG1-CE1 4.02Å; V61-Y398 HydrophobicContact CG1-CE2 4.18Å
62	V	58.5	Low	53.3	Low	95 Å²	95	93.8 Å²	93.8	58%	0.576	53%	0.528	S	S	*	.	P	Polyproline II helix	trans	-63.9	116.5	171.1	179.9	0	0	0	0	106.3	T60 L64 Y398	T60-V62 VanDerWaalsContact C-N 3.31Å; T60-V62 PolarHBondContact O-N 2.81Å; V62-L64 PolarHBondContact O-N 3.49Å; V62-Y398 WeakPolarHBondContact CA-OH 3.45Å; V62-Y398 PolarHBondContact N-OH 3.13Å; V62-Y398 VanDerWaalsContact O-CE2 3.27Å; V62-Y398 WeakPolarHBondContact O-CE2 3.1Å; V62-Y398 PolarHBondContact O-OH 3.21Å
63	P	62.5	Low	54.5	Low	95 Å²	95	93.4 Å²	93.4	62%	0.617	52%	0.523	S	S	*	.	P	Polyproline II helix	trans	-61	131.6	-178.3	23.1	-31.5	0	0	0	109.8	V61 Q65	V61-P63 VanDerWaalsContact O-CD 3.32Å; V61-P63 WeakPolarHBondContact O-CD 3.31Å; P63-Q65 PolarHBondContact O-N 3.35Å; P63-Q65 VanDerWaalsContact O-N 3.13Å
64	L	61.4	Low	56.2	Low	38 Å²	38	94.7 Å²	94.7	20%	0.199	53%	0.527	C	S	.	.	P	Polyproline II helix	trans	-59.2	116.2	172.4	-78.9	162.2	0	0	0	108.9	V62 H66 H353 H397 Y398	V62-L64 PolarHBondContact O-N 3.49Å; L64-H66 PolarHBondContact O-CD2 2.91Å; L64-H66 PolarHBondContact O-N 3.28Å; L64-H66 PolarHBondContact O-NE2 3.28Å; L64-H353 WeakPolarHBondContact CD1-ND1 3.04Å; L64-H397 HydrophobicContact CD2-CB 4.11Å; L64-Y398 HydrophobicContact CD1-CD2 3.98Å; L64-Y398 HydrophobicContact CG-CD2 4.06Å; L64-Y398 HydrophobicContact CG-CE2 4.15Å
65	Q	60.4	Low	57.7	Low	195 Å²	195	93 Å²	93	91%	0.911	51%	0.511	S	S	*	.	P	Polyproline II helix	trans	-73.7	126	174.3	-74.3	-173.2	-3.8	0	0	109.7	P63	P63-Q65 PolarHBondContact O-N 3.35Å; P63-Q65 VanDerWaalsContact O-N 3.13Å
66	H	71.3	Confident	59.1	Low	58 Å²	58	91.6 Å²	91.6	27%	0.269	51%	0.506	S	S	.	.	P	Polyproline II helix	trans	-98.7	134.7	178.3	-70.7	-62.6	0	0	0	110.7	L64 K68 C264 K349 H353	L64-H66 PolarHBondContact O-CD2 2.91Å; L64-H66 PolarHBondContact O-N 3.28Å; L64-H66 PolarHBondContact O-NE2 3.28Å; H66-K68 PolarHBondContact O-N 2.92Å; H66-C264 PolarHBondContact CD2-SG 3.35Å; H66-K349 HydrophobicContact CB-CD 4.45Å; H66-K349 VanDerWaalsContact ND1-CG 3.33Å; H66-K349 WeakPolarHBondContact ND1-CG 3.28Å; H66-H353 AromaticContact CE1-NE2 3.53Å; H66-H353 AromaticContact NE2-CE1 3.93Å; H66-H353 AromaticContact NE2-NE2 3.12Å; H66-H353 PolarHBondContact NE2-NE2 2.58Å; H66-H353 VanDerWaalsContact NE2-NE2 3.12Å
67	C	64.6	Low	60.8	Low	22 Å²	22	88 Å²	88	15%	0.149	49%	0.489	C	S	.	.	P	Polyproline II helix	trans	-60.6	131.5	167.3	-179.9	0	0	0	0	109.7	I69 S480	C67-I69 PolarHBondContact O-N 3Å; C67-S480 VanDerWaalsContact CB-OG 3.27Å; C67-S480 WeakPolarHBondContact CB-OG 3.44Å; C67-S480 PolarHBondContact SG-OG 2.83Å
68	K	64.3	Low	62.5	Low	202 Å²	202	88.2 Å²	88.2	88%	0.878	48%	0.484	S	S	*	.			trans	-83.2	99.7	164.7	-74.3	-173.9	179.7	-179	0	107.8	H66	H66-K68 PolarHBondContact O-N 2.92Å
69	I	64.9	Low	64.5	Low	31 Å²	31	87.7 Å²	87.7	16%	0.159	48%	0.477	C	S	.	.			trans	-76.3	134.9	175.1	-56.8	175	0	0	0	107.9	C67 L72 D345 L473 Y477	C67-I69 PolarHBondContact O-N 3Å; I69-L72 HydrophobicContact CG2-CD1 4.19Å; I69-D345 HydrophobicContact CD1-CB 3.52Å; I69-D345 WeakPolarHBondContact CD1-OD1 3.4Å; I69-L473 HydrophobicContact CD1-CD1 3.74Å; I69-L473 HydrophobicContact CG2-CD1 4.14Å; I69-Y477 HydrophobicContact CD1-CE1 4.48Å; I69-Y477 HydrophobicContact CD1-CE2 4.21Å; I69-Y477 WeakPolarHBondContact CD1-OH 3.08Å
70	P	61.1	Low	66.5	Low	78 Å²	78	82.3 Å²	82.3	51%	0.506	45%	0.452	S	S	.	.			trans	-59.2	139.3	171.7	24.7	-33.2	0	0	0	109.9	L72	P70-L72 PolarHBondContact O-N 3.09Å
71	E	57.3	Low	68.4	Low	193 Å²	193	76.7 Å²	76.7	90%	0.902	42%	0.417	S	S	*	.			trans	-61.4	105.1	173.1	-67.3	-170.2	169.7	0	0	108.6
72	L	61.7	Low	70.1	Confident	35 Å²	35	77.6 Å²	77.6	18%	0.183	42%	0.419	C	S	.	.			trans	-65.4	141.2	172.2	-75.9	101.7	0	0	0	108.1	I69 P70 V74 A341 V472	I69-L72 HydrophobicContact CG2-CD1 4.19Å; P70-L72 PolarHBondContact O-N 3.09Å; L72-V74 PolarHBondContact O-N 2.88Å; L72-A341 HydrophobicContact CD1-CB 3.99Å; L72-V472 HydrophobicContact CD1-CG1 4.36Å; L72-V472 HydrophobicContact CD2-CB 4.21Å; L72-V472 HydrophobicContact CD2-CG1 3.92Å; L72-V472 HydrophobicContact CG-CG1 4.21Å
73	P	58.2	Low	71.7	Confident	107 Å²	107	75.5 Å²	75.5	70%	0.695	40%	0.403	S	S	*	.			trans	-60.1	106.4	178.6	24.6	-33.2	0	0	0	109.2	Q75	P73-Q75 PolarHBondContact O-N 3.02Å
74	V	65.2	Low	73.2	Confident	114 Å²	114	71.1 Å²	71.1	69%	0.691	37%	0.374	S	S	*	.	P	Polyproline II helix	trans	-71.8	118.3	173.2	-177.9	0	0	0	0	106.6	L72 A76	L72-V74 PolarHBondContact O-N 2.88Å; V74-A76 PolarHBondContact O-N 2.84Å
75	Q	67.6	Low	74.7	Confident	59 Å²	59	70.8 Å²	70.8	28%	0.276	37%	0.371	S	S	.	.	P	Polyproline II helix	trans	-57.8	136.5	176.8	-173.5	173.8	8.8	0	0	109.4	P73 S77 L79	P73-Q75 PolarHBondContact O-N 3.02Å; Q75-S77 PolarHBondContact O-N 3.45Å; Q75-L79 HydrophobicContact CG-CB 3.93Å
76	A	73.7	Confident	76.4	Confident	50 Å²	50	66.9 Å²	66.9	41%	0.413	35%	0.352	S	S	.	.	P	Polyproline II helix	trans	-53.7	137.1	174.9	0	0	0	0	0	110.3	V74 I78 L79 F80	V74-A76 PolarHBondContact O-N 2.84Å; A76-I78 HydrophobicContact CB-CG2 4.41Å; A76-I78 PolarHBondContact O-N 2.97Å; A76-L79 HydrophobicContact CB-CB 4.44Å; A76-L79 HydrophobicContact CB-CD1 4.13Å; A76-L79 HydrophobicContact CB-CG 4.21Å; A76-L79 PolarHBondContact O-N 3.46Å; A76-F80 PolarHBondContact O-N 2.97Å; A76-F80 VanDerWaalsContact O-N 3.08Å
77	S	78.5	Confident	77.4	Confident	26 Å²	26	64.9 Å²	64.9	18%	0.182	34%	0.344	C	S	.	.	H	α-helix	trans	-46.7	-47.3	-179.3	49.2	0	0	0	0	112.7	Q75 L79 F80 E81	Q75-S77 PolarHBondContact O-N 3.45Å; S77-L79 PolarHBondContact O-N 3.13Å; S77-F80 PolarHBondContact O-N 2.85Å; S77-E81 PolarHBondContact O-N 2.75Å
78	I	83.4	Confident	78.9	Confident	47 Å²	47	64.2 Å²	64.2	24%	0.241	34%	0.338	C	S	.	.	H	α-helix	trans	-67.1	-36.5	-178.5	-165.5	161.7	0	0	0	113.3	A76 E81 L82 F138 S141 I142 E145	A76-I78 HydrophobicContact CB-CG2 4.41Å; A76-I78 PolarHBondContact O-N 2.97Å; I78-E81 PolarHBondContact O-N 3.49Å; I78-L82 VanDerWaalsContact O-CB 3.25Å; I78-L82 WeakPolarHBondContact O-CB 3.49Å; I78-L82 PolarHBondContact O-N 3.21Å; I78-F138 HydrophobicContact CG1-CE2 4.25Å; I78-S141 WeakPolarHBondContact CA-OG 3.28Å; I78-I142 HydrophobicContact CD1-CG1 3.97Å; I78-E145 HydrophobicContact CD1-CB 4.28Å; I78-E145 HydrophobicContact CD1-CG 4.43Å
79	L	86.7	Confident	80.4	Confident	91 Å²	91	57 Å²	57	48%	0.476	31%	0.31	S	S	.	.	H	α-helix	trans	-71.1	-35.6	178.1	-69.4	177.3	0	0	0	111.2	Q75 A76 S77 Q83	Q75-L79 HydrophobicContact CG-CB 3.93Å; A76-L79 HydrophobicContact CB-CB 4.44Å; A76-L79 HydrophobicContact CB-CD1 4.13Å; A76-L79 HydrophobicContact CB-CG 4.21Å; A76-L79 PolarHBondContact O-N 3.46Å; S77-L79 PolarHBondContact O-N 3.13Å; L79-Q83 WeakPolarHBondContact O-CB 3.22Å; L79-Q83 PolarHBondContact O-N 2.92Å
80	F	89.7	Confident	81.8	Confident	11 Å²	11	56.8 Å²	56.8	5%	0.048	31%	0.308	C	S	.	.	H	α-helix	trans	-64.7	-49.1	173.3	170.3	-96.1	0	0	0	111.2	A76 S77 L82 Q83 L84 Y254 I333 L334 H337	A76-F80 PolarHBondContact O-N 2.97Å; A76-F80 VanDerWaalsContact O-N 3.08Å; S77-F80 PolarHBondContact O-N 2.85Å; F80-L82 VanDerWaalsContact C-N 3.31Å; F80-L82 PolarHBondContact O-N 3.32Å; F80-Q83 PolarHBondContact O-N 3.23Å; F80-L84 HydrophobicContact CE1-CD2 4.27Å; F80-L84 HydrophobicContact CZ-CD2 4.35Å; F80-L84 WeakPolarHBondContact O-CB 3.22Å; F80-L84 PolarHBondContact O-N 3.33Å; F80-Y254 WeakPolarHBondContact CD1-OH 3.25Å; F80-I333 HydrophobicContact CE2-CG2 3.63Å; F80-I333 WeakPolarHBondContact CE2-O 3.35Å; F80-I333 HydrophobicContact CZ-CG2 4.02Å; F80-L334 HydrophobicContact CE1-CD2 4.37Å; F80-L334 HydrophobicContact CZ-CD2 4.1Å; F80-H337 HydrophobicContact CD1-CB 4.16Å; F80-H337 AromaticContact CD1-CD2 3.76Å; F80-H337 AromaticContact CD1-CE1 3.99Å; F80-H337 AromaticContact CD1-CG 3.54Å; F80-H337 AromaticContact CD1-ND1 3.69Å; F80-H337 HydrophobicContact CD2-CB 3.78Å; F80-H337 AromaticContact CD2-CG 3.83Å; F80-H337 AromaticContact CD2-ND1 3.8Å; F80-H337 HydrophobicContact CE1-CB 3.75Å; F80-H337 AromaticContact CE1-CD2 3.65Å; F80-H337 AromaticContact CE1-CG 3.51Å; F80-H337 HydrophobicContact CE2-CB 3.35Å; F80-H337 AromaticContact CE2-CG 3.81Å; F80-H337 HydrophobicContact CG-CB 4.16Å; F80-H337 AromaticContact CG-CG 3.69Å; F80-H337 AromaticContact CG-ND1 3.48Å; F80-H337 WeakPolarHBondContact CG-ND1 3.36Å; F80-H337 HydrophobicContact CZ-CB 3.32Å; F80-H337 AromaticContact CZ-CG 3.65Å
81	E	90.5	Very high	83.5	Confident	3 Å²	3	53.4 Å²	53.4	1%	0.014	29%	0.287	C	S	.	.	H	α-helix	trans	-64.3	-36.7	178.9	-70.5	-66	177	0	0	112.3	S77 I78 L84 F85 R137 F138 Y254	S77-E81 PolarHBondContact O-N 2.75Å; I78-E81 PolarHBondContact O-N 3.49Å; E81-L84 PolarHBondContact O-N 3.33Å; E81-F85 VanDerWaalsContact O-CB 3.22Å; E81-F85 WeakPolarHBondContact O-CB 3.39Å; E81-F85 PolarHBondContact O-N 2.99Å; E81-R137 IonicContact OE1-CZ 3.27Å; E81-R137 VanDerWaalsContact OE1-CZ 3.27Å; E81-R137 IonicContact OE1-NE 2.91Å; E81-R137 PolarHBondContact OE1-NE 3.48Å; E81-R137 IonicContact OE1-NH2 2.78Å; E81-R137 PolarHBondContact OE1-NH2 2.99Å; E81-R137 WeakPolarHBondContact OE2-CB 3.48Å; E81-R137 IonicContact OE2-CZ 3.86Å; E81-R137 IonicContact OE2-NE 3.09Å; E81-R137 PolarHBondContact OE2-NE 3.22Å; E81-R137 VanDerWaalsContact OE2-NE 3.09Å; E81-R137 IonicContact OE2-NH2 3.86Å; E81-F138 HydrophobicContact CB-CB 4.34Å; E81-F138 HydrophobicContact CB-CD2 4.22Å; E81-Y254 HydrophobicContact CG-CE2 3.92Å; E81-Y254 WeakPolarHBondContact CG-OH 3.48Å; E81-Y254 VanDerWaalsContact OE1-CE2 3.22Å; E81-Y254 WeakPolarHBondContact OE1-CE2 3.41Å; E81-Y254 VanDerWaalsContact OE1-CZ 3.23Å; E81-Y254 PolarHBondContact OE1-OH 2.97Å
82	L	91.3	Very high	85.3	Confident	79 Å²	79	44.3 Å²	44.3	41%	0.414	25%	0.245	S	C	.	.	H	α-helix	trans	-61.7	-47	172.9	178.6	62.6	0	0	0	111.4	I78 F80 F85 F86 F138	I78-L82 VanDerWaalsContact O-CB 3.25Å; I78-L82 WeakPolarHBondContact O-CB 3.49Å; I78-L82 PolarHBondContact O-N 3.21Å; F80-L82 VanDerWaalsContact C-N 3.31Å; F80-L82 PolarHBondContact O-N 3.32Å; L82-F85 PolarHBondContact O-N 3.39Å; L82-F86 WeakPolarHBondContact O-CB 3.44Å; L82-F86 PolarHBondContact O-N 3.4Å; L82-F138 HydrophobicContact CB-CD2 4.15Å; L82-F138 HydrophobicContact CB-CE2 3.76Å; L82-F138 HydrophobicContact CB-CZ 4.47Å; L82-F138 HydrophobicContact CD1-CE1 4.28Å; L82-F138 HydrophobicContact CD1-CE2 3.83Å; L82-F138 HydrophobicContact CD1-CZ 3.66Å; L82-F138 HydrophobicContact CG-CE2 4.34Å
83	Q	91.4	Very high	86.8	Confident	52 Å²	52	48 Å²	48	24%	0.243	26%	0.259	C	S	.	.	H	α-helix	trans	-60.7	-48.3	178.1	-180	67.4	11.2	0	0	111	L79 F80 F85 F86 C87 Y461	L79-Q83 WeakPolarHBondContact O-CB 3.22Å; L79-Q83 PolarHBondContact O-N 2.92Å; F80-Q83 PolarHBondContact O-N 3.23Å; Q83-F85 VanDerWaalsContact C-N 3.33Å; Q83-F85 PolarHBondContact O-N 2.91Å; Q83-F86 PolarHBondContact O-N 2.81Å; Q83-C87 PolarHBondContact O-N 3.41Å; Q83-C87 PolarHBondContact O-SG 2.86Å; Q83-Y461 HydrophobicContact CG-CD1 4.31Å; Q83-Y461 HydrophobicContact CG-CE1 3.96Å; Q83-Y461 VanDerWaalsContact NE2-CD1 3.27Å
84	L	92.9	Very high	88.5	Confident	2 Å²	2	43 Å²	43	1%	0.01	23%	0.226	C	C	.	.	H	α-helix	trans	-59.7	-45.6	178.8	176.8	61.9	0	0	0	111.1	F80 E81 F86 C87 Q88 T330 I333 L334	F80-L84 HydrophobicContact CE1-CD2 4.27Å; F80-L84 HydrophobicContact CZ-CD2 4.35Å; F80-L84 WeakPolarHBondContact O-CB 3.22Å; F80-L84 PolarHBondContact O-N 3.33Å; E81-L84 PolarHBondContact O-N 3.33Å; L84-F86 PolarHBondContact O-N 2.76Å; L84-C87 PolarHBondContact O-N 3.38Å; L84-Q88 WeakPolarHBondContact O-CG 3.19Å; L84-Q88 PolarHBondContact O-N 2.96Å; L84-T330 HydrophobicContact CD1-CG2 4.09Å; L84-I333 HydrophobicContact CD1-CG2 4.03Å; L84-L334 HydrophobicContact CD2-CD2 3.76Å
85	F	94.7	Very high	89.9	Confident	32 Å²	32	37.5 Å²	37.5	14%	0.14	19%	0.193	C	C	.	.	H	α-helix	trans	-61	-44.8	177.1	-179.7	-126.1	0	0	0	111.5	E81 L82 Q83 C87 Q88 L89 T131 L134 F138	E81-F85 VanDerWaalsContact O-CB 3.22Å; E81-F85 WeakPolarHBondContact O-CB 3.39Å; E81-F85 PolarHBondContact O-N 2.99Å; L82-F85 PolarHBondContact O-N 3.39Å; Q83-F85 VanDerWaalsContact C-N 3.33Å; Q83-F85 PolarHBondContact O-N 2.91Å; F85-C87 VanDerWaalsContact C-N 3.35Å; F85-C87 PolarHBondContact O-N 3.38Å; F85-Q88 WeakPolarHBondContact O-CB 3.46Å; F85-Q88 PolarHBondContact O-N 3.2Å; F85-L89 HydrophobicContact CD1-CD1 4.1Å; F85-L89 HydrophobicContact CD2-CG 4.31Å; F85-L89 HydrophobicContact CE1-CD1 3.66Å; F85-L89 HydrophobicContact CE1-CG 4.25Å; F85-L89 HydrophobicContact CE2-CD1 4.3Å; F85-L89 HydrophobicContact CE2-CD2 3.89Å; F85-L89 HydrophobicContact CE2-CG 3.99Å; F85-L89 HydrophobicContact CZ-CD1 3.78Å; F85-L89 HydrophobicContact CZ-CD2 3.89Å; F85-L89 HydrophobicContact CZ-CG 3.96Å; F85-L89 WeakPolarHBondContact O-CG 3.14Å; F85-L89 PolarHBondContact O-N 2.84Å; F85-T131 HydrophobicContact CE2-CG2 4.31Å; F85-T131 HydrophobicContact CZ-CG2 3.99Å; F85-L134 HydrophobicContact CE2-CB 4.43Å; F85-F138 HydrophobicContact CB-CB 4.2Å; F85-F138 AromaticContact CD1-CD1 3.84Å; F85-F138 HydrophobicContact CD1-CD1 3.84Å; F85-F138 HydrophobicContact CD1-CE1 4.35Å; F85-F138 HydrophobicContact CD1-CG 4.35Å; F85-F138 HydrophobicContact CE1-CD1 4.21Å; F85-F138 HydrophobicContact CG-CB 4.37Å; F85-F138 HydrophobicContact CG-CD1 4.45Å
86	F	94.3	Very high	91.1	Very high	113 Å²	113	35.2 Å²	35.2	50%	0.496	18%	0.182	S	C	.	.	H	α-helix	trans	-61.6	-41.3	177.3	-171.9	-108	0	0	0	112.5	L82 Q83 L84 Q88 L89 I90	L82-F86 WeakPolarHBondContact O-CB 3.44Å; L82-F86 PolarHBondContact O-N 3.4Å; Q83-F86 PolarHBondContact O-N 2.81Å; L84-F86 PolarHBondContact O-N 2.76Å; F86-Q88 VanDerWaalsContact C-N 3.32Å; F86-Q88 PolarHBondContact O-N 3.13Å; F86-L89 PolarHBondContact O-N 2.91Å; F86-I90 HydrophobicContact CD1-CD1 3.64Å; F86-I90 HydrophobicContact CD1-CG1 4.45Å; F86-I90 HydrophobicContact CE1-CD1 3.36Å; F86-I90 HydrophobicContact CE1-CG1 4.2Å; F86-I90 HydrophobicContact CG-CD1 4.47Å; F86-I90 HydrophobicContact CZ-CD1 3.97Å; F86-I90 HydrophobicContact CZ-CG1 4.38Å; F86-I90 WeakPolarHBondContact O-CG1 3.41Å; F86-I90 PolarHBondContact O-N 2.88Å
87	C	94.1	Very high	91.9	Very high	15 Å²	15	33.4 Å²	33.4	10%	0.101	17%	0.165	C	C	.	.	H	α-helix	trans	-62.4	-40.1	175.6	-60.8	0	0	0	0	111.6	Q83 L84 F85 I90 A91 S458	Q83-C87 PolarHBondContact O-N 3.41Å; Q83-C87 PolarHBondContact O-SG 2.86Å; L84-C87 PolarHBondContact O-N 3.38Å; F85-C87 VanDerWaalsContact C-N 3.35Å; F85-C87 PolarHBondContact O-N 3.38Å; C87-I90 PolarHBondContact O-N 2.86Å; C87-A91 PolarHBondContact O-N 2.79Å; C87-S458 WeakPolarHBondContact CB-OG 3.48Å; C87-S458 PolarHBondContact SG-OG 3.47Å
88	Q	95.5	Very high	92.4	Very high	8 Å²	8	32.7 Å²	32.7	4%	0.037	16%	0.16	C	C	.	.	H	α-helix	trans	-68.2	-38.1	175.8	-69.4	169.3	-3	0	0	112.4	L84 F85 F86 A91 L92 L134 S296	L84-Q88 WeakPolarHBondContact O-CG 3.19Å; L84-Q88 PolarHBondContact O-N 2.96Å; F85-Q88 WeakPolarHBondContact O-CB 3.46Å; F85-Q88 PolarHBondContact O-N 3.2Å; F86-Q88 VanDerWaalsContact C-N 3.32Å; F86-Q88 PolarHBondContact O-N 3.13Å; Q88-A91 PolarHBondContact O-N 3.07Å; Q88-L92 VanDerWaalsContact O-CB 3.31Å; Q88-L92 WeakPolarHBondContact O-CB 3.4Å; Q88-L92 PolarHBondContact O-N 3.1Å; Q88-L134 HydrophobicContact CB-CD1 4.39Å; Q88-S296 PolarHBondContact NE2-OG 3.36Å
89	L	95.7	Very high	92.8	Very high	52 Å²	52	30.6 Å²	30.6	27%	0.272	15%	0.149	S	C	.	.	H	α-helix	trans	-64	-42.3	174.4	-71.4	-178.2	0	0	0	111.9	F85 F86 A91 L92 F93 T131	F85-L89 HydrophobicContact CD1-CD1 4.1Å; F85-L89 HydrophobicContact CD2-CG 4.31Å; F85-L89 HydrophobicContact CE1-CD1 3.66Å; F85-L89 HydrophobicContact CE1-CG 4.25Å; F85-L89 HydrophobicContact CE2-CD1 4.3Å; F85-L89 HydrophobicContact CE2-CD2 3.89Å; F85-L89 HydrophobicContact CE2-CG 3.99Å; F85-L89 HydrophobicContact CZ-CD1 3.78Å; F85-L89 HydrophobicContact CZ-CD2 3.89Å; F85-L89 HydrophobicContact CZ-CG 3.96Å; F85-L89 WeakPolarHBondContact O-CG 3.14Å; F85-L89 PolarHBondContact O-N 2.84Å; F86-L89 PolarHBondContact O-N 2.91Å; L89-A91 VanDerWaalsContact C-N 3.35Å; L89-L92 PolarHBondContact O-N 3.47Å; L89-F93 VanDerWaalsContact O-CB 3.27Å; L89-F93 WeakPolarHBondContact O-CB 3.47Å; L89-F93 PolarHBondContact O-N 3.29Å; L89-T131 HydrophobicContact CD2-CG2 3.83Å
90	I	94.6	Very high	93	Very high	25 Å²	25	26.8 Å²	26.8	13%	0.128	13%	0.128	C	C	.	.	H	α-helix	trans	-58.9	-49.9	174.3	-71.2	165.1	0	0	0	109.8	F86 C87 L92 F93 V94 L454	F86-I90 HydrophobicContact CD1-CD1 3.64Å; F86-I90 HydrophobicContact CD1-CG1 4.45Å; F86-I90 HydrophobicContact CE1-CD1 3.36Å; F86-I90 HydrophobicContact CE1-CG1 4.2Å; F86-I90 HydrophobicContact CG-CD1 4.47Å; F86-I90 HydrophobicContact CZ-CD1 3.97Å; F86-I90 HydrophobicContact CZ-CG1 4.38Å; F86-I90 WeakPolarHBondContact O-CG1 3.41Å; F86-I90 PolarHBondContact O-N 2.88Å; C87-I90 PolarHBondContact O-N 2.86Å; I90-L92 VanDerWaalsContact C-N 3.32Å; I90-L92 PolarHBondContact O-N 3.42Å; I90-F93 PolarHBondContact O-N 2.99Å; I90-V94 HydrophobicContact CG2-CG2 4.33Å; I90-V94 VanDerWaalsContact O-CB 3.27Å; I90-V94 WeakPolarHBondContact O-CB 3.43Å; I90-V94 VanDerWaalsContact O-CG2 3.29Å; I90-V94 WeakPolarHBondContact O-CG2 3.31Å; I90-V94 PolarHBondContact O-N 3.49Å; I90-L454 HydrophobicContact CG2-CB 3.8Å
91	A	95.5	Very high	92.8	Very high	7 Å²	7	29.3 Å²	29.3	6%	0.058	14%	0.139	C	C	.	.	H	α-helix	trans	-62.5	-39.6	-179.3	0	0	0	0	0	112.2	C87 Q88 L89 H95 V300 V326	C87-A91 PolarHBondContact O-N 2.79Å; Q88-A91 PolarHBondContact O-N 3.07Å; L89-A91 VanDerWaalsContact C-N 3.35Å; A91-H95 WeakPolarHBondContact O-CB 3.36Å; A91-H95 PolarHBondContact O-N 3.49Å; A91-V300 HydrophobicContact CB-CG1 3.7Å; A91-V326 HydrophobicContact CB-CG2 3.82Å
92	L	96	Very high	92.3	Very high	3 Å²	3	29.6 Å²	29.6	2%	0.016	14%	0.141	C	C	.	.	H	α-helix	trans	-63.1	-51.4	174.9	-173.4	67.7	0	0	0	111	Q88 L89 I90 V94 H95 Y96 L127 T130 L134 P304	Q88-L92 VanDerWaalsContact O-CB 3.31Å; Q88-L92 WeakPolarHBondContact O-CB 3.4Å; Q88-L92 PolarHBondContact O-N 3.1Å; L89-L92 PolarHBondContact O-N 3.47Å; I90-L92 VanDerWaalsContact C-N 3.32Å; I90-L92 PolarHBondContact O-N 3.42Å; L92-V94 VanDerWaalsContact C-N 3.32Å; L92-V94 PolarHBondContact O-N 2.88Å; L92-H95 WeakPolarHBondContact O-CB 3.44Å; L92-H95 PolarHBondContact O-N 3.02Å; L92-Y96 HydrophobicContact CD1-CD2 4.09Å; L92-Y96 HydrophobicContact CD1-CE2 3.72Å; L92-Y96 HydrophobicContact CG-CD2 4.12Å; L92-Y96 HydrophobicContact CG-CE2 4.04Å; L92-Y96 WeakPolarHBondContact O-CD2 3.46Å; L92-Y96 PolarHBondContact O-N 3.39Å; L92-L127 HydrophobicContact CD2-CD1 3.71Å; L92-L127 HydrophobicContact CG-CD1 4.16Å; L92-T130 HydrophobicContact CD1-CG2 3.85Å; L92-T130 HydrophobicContact CD2-CG2 4.14Å; L92-L134 HydrophobicContact CD2-CD1 4.19Å; L92-P304 HydrophobicContact CD1-CG 4.03Å
93	F	94	Very high	91.4	Very high	113 Å²	113	30.1 Å²	30.1	50%	0.496	15%	0.148	S	C	.	.	H	α-helix	trans	-56.4	-47.2	178.4	173.8	-110.2	0	0	0	111.9	L89 I90 H95 Y96 I97	L89-F93 VanDerWaalsContact O-CB 3.27Å; L89-F93 WeakPolarHBondContact O-CB 3.47Å; L89-F93 PolarHBondContact O-N 3.29Å; I90-F93 PolarHBondContact O-N 2.99Å; F93-H95 VanDerWaalsContact C-N 3.3Å; F93-H95 PolarHBondContact O-N 3.3Å; F93-Y96 PolarHBondContact O-N 3.03Å; F93-I97 HydrophobicContact CD1-CD1 3.85Å; F93-I97 HydrophobicContact CE1-CD1 3.35Å; F93-I97 HydrophobicContact CE1-CG1 4.39Å; F93-I97 HydrophobicContact CE2-CD1 4.22Å; F93-I97 HydrophobicContact CE2-CG1 4.47Å; F93-I97 HydrophobicContact CG-CD1 4.49Å; F93-I97 HydrophobicContact CZ-CD1 3.56Å; F93-I97 HydrophobicContact CZ-CG1 4.25Å; F93-I97 PolarHBondContact O-N 3.37Å
94	V	92.8	Very high	90.3	Very high	0 Å²	0	34.4 Å²	34.4	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-57.3	-43.3	174.4	157.5	0	0	0	0	111.3	I90 L92 Y96 I97 N98 S451 L454 I455	I90-V94 HydrophobicContact CG2-CG2 4.33Å; I90-V94 VanDerWaalsContact O-CB 3.27Å; I90-V94 WeakPolarHBondContact O-CB 3.43Å; I90-V94 VanDerWaalsContact O-CG2 3.29Å; I90-V94 WeakPolarHBondContact O-CG2 3.31Å; I90-V94 PolarHBondContact O-N 3.49Å; L92-V94 VanDerWaalsContact C-N 3.32Å; L92-V94 PolarHBondContact O-N 2.88Å; V94-Y96 PolarHBondContact O-N 3.21Å; V94-I97 WeakPolarHBondContact O-CB 3.4Å; V94-I97 PolarHBondContact O-N 2.83Å; V94-N98 PolarHBondContact O-N 3.37Å; V94-N98 VanDerWaalsContact O-N 3.1Å; V94-N98 PolarHBondContact O-ND2 3.33Å; V94-S451 VanDerWaalsContact CG1-OG 3.31Å; V94-S451 WeakPolarHBondContact CG1-OG 3.3Å; V94-L454 HydrophobicContact CG2-CB 4Å; V94-L454 HydrophobicContact CG2-CD1 3.74Å; V94-I455 HydrophobicContact CG1-CD1 3.87Å; V94-I455 HydrophobicContact CG1-CG1 4.45Å
95	H	94.4	Very high	89.1	Confident	0 Å²	0	40.8 Å²	40.8	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-63.4	-43	177.7	-163.4	40.6	0	0	0	112.6	A91 L92 F93 I97 N98 I99 V300 A301 V305 L322	A91-H95 WeakPolarHBondContact O-CB 3.36Å; A91-H95 PolarHBondContact O-N 3.49Å; L92-H95 WeakPolarHBondContact O-CB 3.44Å; L92-H95 PolarHBondContact O-N 3.02Å; F93-H95 VanDerWaalsContact C-N 3.3Å; F93-H95 PolarHBondContact O-N 3.3Å; H95-I97 VanDerWaalsContact C-N 3.31Å; H95-I97 PolarHBondContact O-N 3.16Å; H95-N98 WeakPolarHBondContact O-CB 3.4Å; H95-N98 PolarHBondContact O-N 2.91Å; H95-N98 VanDerWaalsContact O-N 3.07Å; H95-I99 WeakPolarHBondContact O-CG1 3.35Å; H95-I99 PolarHBondContact O-N 3.4Å; H95-V300 PolarHBondContact CD2-O 3.37Å; H95-A301 PolarHBondContact NE2-O 3.17Å; H95-V305 WeakPolarHBondContact NE2-CG2 3.41Å; H95-L322 HydrophobicContact CB-CD2 3.53Å; H95-L322 VanDerWaalsContact ND1-CD2 3.32Å; H95-L322 WeakPolarHBondContact ND1-CD2 2.98Å
96	Y	93	Very high	87.6	Confident	11 Å²	11	47.5 Å²	47.5	4%	0.043	21%	0.211	C	C	.	.	H	α-helix	trans	-62.6	-37	176	-88.3	-98	0	0	0	112.3	L92 F93 V94 N98 I99 Y100 I122 L127 P304	L92-Y96 HydrophobicContact CD1-CD2 4.09Å; L92-Y96 HydrophobicContact CD1-CE2 3.72Å; L92-Y96 HydrophobicContact CG-CD2 4.12Å; L92-Y96 HydrophobicContact CG-CE2 4.04Å; L92-Y96 WeakPolarHBondContact O-CD2 3.46Å; L92-Y96 PolarHBondContact O-N 3.39Å; F93-Y96 PolarHBondContact O-N 3.03Å; V94-Y96 PolarHBondContact O-N 3.21Å; Y96-N98 VanDerWaalsContact C-N 3.32Å; Y96-N98 PolarHBondContact O-N 3.07Å; Y96-I99 PolarHBondContact O-N 3.32Å; Y96-Y100 AromaticContact CD1-CD2 3.67Å; Y96-Y100 HydrophobicContact CD1-CD2 3.67Å; Y96-Y100 AromaticContact CD1-CE2 3.48Å; Y96-Y100 HydrophobicContact CD1-CE2 3.48Å; Y96-Y100 VanDerWaalsContact CD1-CE2 3.48Å; Y96-Y100 HydrophobicContact CE1-CD2 4.36Å; Y96-Y100 AromaticContact CE1-CE2 3.71Å; Y96-Y100 HydrophobicContact CE1-CE2 3.71Å; Y96-Y100 HydrophobicContact CG-CD2 4.44Å; Y96-Y100 HydrophobicContact CG-CE2 4.46Å; Y96-Y100 WeakPolarHBondContact O-CD2 3.48Å; Y96-Y100 PolarHBondContact O-N 3.36Å; Y96-I122 HydrophobicContact CD1-CD1 4.25Å; Y96-I122 HydrophobicContact CD1-CG1 4.2Å; Y96-I122 HydrophobicContact CD1-CG2 3.98Å; Y96-I122 HydrophobicContact CE1-CG2 3.82Å; Y96-L127 HydrophobicContact CD2-CD1 4.17Å; Y96-L127 HydrophobicContact CE1-CD1 4.43Å; Y96-L127 HydrophobicContact CE2-CD1 3.66Å; Y96-P304 HydrophobicContact CD2-CB 4.47Å; Y96-P304 HydrophobicContact CD2-CG 4.48Å; Y96-P304 HydrophobicContact CE2-CB 3.86Å; Y96-P304 HydrophobicContact CE2-CG 3.72Å
97	I	90.8	Very high	85.6	Confident	11 Å²	11	46.6 Å²	46.6	6%	0.056	22%	0.217	C	C	.	.	H	α-helix	trans	-58.5	-46.7	171.2	-70.8	167.2	0	0	0	110.5	F93 V94 H95 I99 K101 L117 W446 H447	F93-I97 HydrophobicContact CD1-CD1 3.85Å; F93-I97 HydrophobicContact CE1-CD1 3.35Å; F93-I97 HydrophobicContact CE1-CG1 4.39Å; F93-I97 HydrophobicContact CE2-CD1 4.22Å; F93-I97 HydrophobicContact CE2-CG1 4.47Å; F93-I97 HydrophobicContact CG-CD1 4.49Å; F93-I97 HydrophobicContact CZ-CD1 3.56Å; F93-I97 HydrophobicContact CZ-CG1 4.25Å; F93-I97 PolarHBondContact O-N 3.37Å; V94-I97 WeakPolarHBondContact O-CB 3.4Å; V94-I97 PolarHBondContact O-N 2.83Å; H95-I97 VanDerWaalsContact C-N 3.31Å; H95-I97 PolarHBondContact O-N 3.16Å; I97-I99 VanDerWaalsContact C-N 3.3Å; I97-I99 PolarHBondContact O-N 3.47Å; I97-K101 WeakPolarHBondContact O-CB 3.37Å; I97-K101 PolarHBondContact O-N 3.15Å; I97-K101 VanDerWaalsContact O-N 3.09Å; I97-L117 HydrophobicContact CB-CD2 4.18Å; I97-L117 HydrophobicContact CG1-CD1 4Å; I97-L117 HydrophobicContact CG1-CD2 4.05Å; I97-L117 HydrophobicContact CG2-CD2 4.17Å; I97-W446 HydrophobicContact CG2-CH2 4.05Å; I97-W446 HydrophobicContact CG2-CZ3 4.24Å; I97-H447 HydrophobicContact CG2-CB 4.07Å
98	N	89.7	Confident	84	Confident	11 Å²	11	49.3 Å²	49.3	6%	0.059	23%	0.234	C	C	.	.	H	α-helix	trans	-66.6	-32.1	-176.9	-69	-50.3	0	0	0	113.2	V94 H95 Y96 W318 H447 S451	V94-N98 PolarHBondContact O-N 3.37Å; V94-N98 VanDerWaalsContact O-N 3.1Å; V94-N98 PolarHBondContact O-ND2 3.33Å; H95-N98 WeakPolarHBondContact O-CB 3.4Å; H95-N98 PolarHBondContact O-N 2.91Å; H95-N98 VanDerWaalsContact O-N 3.07Å; Y96-N98 VanDerWaalsContact C-N 3.32Å; Y96-N98 PolarHBondContact O-N 3.07Å; N98-W318 PolarHBondContact ND2-NE1 2.87Å; N98-H447 PolarHBondContact OD1-CD2 2.79Å; N98-H447 VanDerWaalsContact OD1-CD2 3.28Å; N98-S451 PolarHBondContact ND2-OG 3.32Å; N98-S451 PolarHBondContact OD1-OG 3.19Å; N98-S451 VanDerWaalsContact OD1-OG 3.13Å
99	I	91.1	Very high	82.1	Confident	3 Å²	3	54.3 Å²	54.3	2%	0.015	27%	0.27	C	S	.	.	H	α-helix	trans	-76.6	-53.2	175.8	-65.2	169	0	0	0	110.7	H95 Y96 I97 P304 V305 V308 H312	H95-I99 WeakPolarHBondContact O-CG1 3.35Å; H95-I99 PolarHBondContact O-N 3.4Å; Y96-I99 PolarHBondContact O-N 3.32Å; I97-I99 VanDerWaalsContact C-N 3.3Å; I97-I99 PolarHBondContact O-N 3.47Å; I99-P304 HydrophobicContact CD1-CB 3.74Å; I99-V305 HydrophobicContact CD1-CG2 4.07Å; I99-V308 HydrophobicContact CD1-CG2 4.34Å; I99-V308 HydrophobicContact CG2-CG2 3.45Å; I99-V308 VanDerWaalsContact CG2-CG2 3.45Å; I99-H312 PolarHBondContact O-NE2 3.47Å
100	Y	90.1	Very high	80	Confident	12 Å²	12	59.1 Å²	59.1	5%	0.047	29%	0.291	C	S	.	.	H	α-helix	trans	-102.3	20.3	-165.6	-61.7	-75	0	0	0	114.8	Y96 L117 N118 L121 I122	Y96-Y100 AromaticContact CD1-CD2 3.67Å; Y96-Y100 HydrophobicContact CD1-CD2 3.67Å; Y96-Y100 AromaticContact CD1-CE2 3.48Å; Y96-Y100 HydrophobicContact CD1-CE2 3.48Å; Y96-Y100 VanDerWaalsContact CD1-CE2 3.48Å; Y96-Y100 HydrophobicContact CE1-CD2 4.36Å; Y96-Y100 AromaticContact CE1-CE2 3.71Å; Y96-Y100 HydrophobicContact CE1-CE2 3.71Å; Y96-Y100 HydrophobicContact CG-CD2 4.44Å; Y96-Y100 HydrophobicContact CG-CE2 4.46Å; Y96-Y100 WeakPolarHBondContact O-CD2 3.48Å; Y96-Y100 PolarHBondContact O-N 3.36Å; Y100-L117 WeakPolarHBondContact O-CA 3.4Å; Y100-N118 PolarHBondContact O-N 2.88Å; Y100-L121 HydrophobicContact CD1-CB 3.56Å; Y100-L121 HydrophobicContact CD1-CD1 4.3Å; Y100-L121 HydrophobicContact CE1-CB 3.57Å; Y100-L121 WeakPolarHBondContact CE1-O 3.31Å; Y100-L121 PolarHBondContact OH-O 3.34Å; Y100-I122 HydrophobicContact CD1-CG1 4.27Å; Y100-I122 HydrophobicContact CD2-CD1 4.17Å; Y100-I122 HydrophobicContact CD2-CG1 3.59Å; Y100-I122 HydrophobicContact CE2-CG1 3.88Å; Y100-I122 HydrophobicContact CG-CD1 4.41Å; Y100-I122 HydrophobicContact CG-CG1 3.77Å
101	K	85.5	Confident	78	Confident	63 Å²	63	63.5 Å²	63.5	27%	0.274	32%	0.321	S	S	.	.	B	Isolated β-bridge	trans	-54.4	146.6	175.1	61.6	-174.6	174.4	-171.3	0	113.3	I97 W446 H447	I97-K101 WeakPolarHBondContact O-CB 3.37Å; I97-K101 PolarHBondContact O-N 3.15Å; I97-K101 VanDerWaalsContact O-N 3.09Å; K101-W446 HydrophobicContact CB-CZ2 4.17Å; K101-H447 PolarHBondContact NZ-CE1 2.76Å; K101-H447 PolarHBondContact NZ-NE2 2.83Å
102	T	79.8	Confident	76.1	Confident	10 Å²	10	66.2 Å²	66.2	6%	0.061	34%	0.338	C	S	.	.			trans	-117.9	156.9	167.8	57.6	0	0	0	0	110.9	W104 T115 S116 N118	T102-W104 VanDerWaalsContact C-N 3.32Å; T102-W104 PolarHBondContact O-N 2.99Å; T102-T115 PolarHBondContact OG1-O 3.45Å; T102-S116 PolarHBondContact N-O 2.86Å; T102-S116 VanDerWaalsContact OG1-CA 3.31Å; T102-S116 WeakPolarHBondContact OG1-CA 3.49Å; T102-S116 PolarHBondContact OG1-O 3.43Å; T102-N118 HydrophobicContact CG2-CB 4.14Å; T102-N118 WeakPolarHBondContact CG2-ND2 3.05Å; T102-N118 WeakPolarHBondContact CG2-OD1 3.48Å
103	V	72.8	Confident	74.4	Confident	90 Å²	90	67.9 Å²	67.9	55%	0.545	35%	0.35	S	S	.	.			trans	-89.3	76.3	167.4	-171.7	0	0	0	0	107.7	W105	V103-W105 VanDerWaalsContact C-N 3.32Å; V103-W105 HydrophobicContact CG1-CD2 4.34Å; V103-W105 HydrophobicContact CG1-CH2 4.48Å; V103-W105 HydrophobicContact CG1-CZ2 3.97Å; V103-W105 PolarHBondContact O-N 3.02Å
104	W	68.4	Low	73.1	Confident	141 Å²	141	71 Å²	71	53%	0.534	37%	0.365	S	S	.	.	T	Hydrogen-bonded Turn	trans	-75.2	-18.2	-173	62.1	-88.2	0	0	0	114	T102	T102-W104 VanDerWaalsContact C-N 3.32Å; T102-W104 PolarHBondContact O-N 2.99Å
105	W	69.2	Low	72.4	Confident	137 Å²	137	74 Å²	74	52%	0.519	38%	0.384	S	S	.	.	T	Hydrogen-bonded Turn	trans	-92.1	-4.8	-179.4	63.6	82.2	0	0	0	114.2	V103 W446	V103-W105 VanDerWaalsContact C-N 3.32Å; V103-W105 HydrophobicContact CG1-CD2 4.34Å; V103-W105 HydrophobicContact CG1-CH2 4.48Å; V103-W105 HydrophobicContact CG1-CZ2 3.97Å; V103-W105 PolarHBondContact O-N 3.02Å; W105-W446 AromaticContact CH2-CD1 3.24Å; W105-W446 HydrophobicContact CH2-CG 4.36Å; W105-W446 AromaticContact CH2-NE1 3.14Å; W105-W446 AromaticContact CZ3-CD1 3.55Å; W105-W446 AromaticContact CZ3-CE2 3.95Å; W105-W446 HydrophobicContact CZ3-CG 4.35Å; W105-W446 AromaticContact CZ3-NE1 3.26Å; W105-W446 VanDerWaalsContact CZ3-NE1 3.26Å
106	Y	61.7	Low	71.6	Confident	172 Å²	172	76.3 Å²	76.3	68%	0.675	40%	0.4	S	S	*	.	S	Bend	trans	-90.5	133.7	178.7	-169.2	-95.8	0	0	0	110.8
107	P	53.6	Low	71.2	Confident	95 Å²	95	76.4 Å²	76.4	62%	0.617	40%	0.401	S	S	*	.	P	Polyproline II helix	trans	-65.3	136.6	-178.8	-17.4	30.4	0	0	0	112.2
108	P	59.9	Low	70.8	Confident	71 Å²	71	77.6 Å²	77.6	46%	0.461	41%	0.408	S	S	.	.	P	Polyproline II helix	trans	-84	129	-165.3	30.6	-34.4	0	0	0	114.3	H110 P112	P108-H110 VanDerWaalsContact C-N 3.3Å; P108-H110 WeakPolarHBondContact CB-O 3.47Å; P108-P112 HydrophobicContact CB-CB 4.16Å; P108-P112 HydrophobicContact CG-CB 3.8Å; P108-P112 HydrophobicContact CG-CG 3.91Å
109	S	55.8	Low	70.7	Confident	113 Å²	113	81.7 Å²	81.7	79%	0.79	43%	0.425	S	S	*	.	S	Bend	trans	-82.4	-10.1	148.5	48.9	0	0	0	0	112.5
110	H	50.4	Low	70.4	Confident	153 Å²	153	88.8 Å²	88.8	71%	0.708	46%	0.458	S	S	*	.	S	Bend	trans	-144.5	146.2	176.6	-75.2	-65.1	0	0	0	109.3	P108	P108-H110 VanDerWaalsContact C-N 3.3Å; P108-H110 WeakPolarHBondContact CB-O 3.47Å
111	P	53.8	Low	70.2	Confident	117 Å²	117	90.6 Å²	90.6	76%	0.76	47%	0.468	S	S	*	.			trans	-48	130.5	-150.4	19.5	-32.9	0	0	0	112.1	S113	P111-S113 PolarHBondContact O-N 3.46Å; P111-S113 VanDerWaalsContact O-N 3.13Å
112	P	54.2	Low	70.4	Confident	65 Å²	65	88.5 Å²	88.5	42%	0.422	46%	0.46	S	S	.	.			trans	-56.3	124.1	-173.9	21.4	-27.5	0	0	0	108.6	P108 H114	P108-P112 HydrophobicContact CB-CB 4.16Å; P108-P112 HydrophobicContact CG-CB 3.8Å; P108-P112 HydrophobicContact CG-CG 3.91Å; P112-H114 VanDerWaalsContact C-N 3.32Å; P112-H114 PolarHBondContact O-CD2 3.29Å; P112-H114 PolarHBondContact O-N 3.35Å
113	S	60.9	Low	71	Confident	37 Å²	37	89.1 Å²	89.1	26%	0.259	46%	0.462	S	S	.	.			trans	-64.6	100.7	165.9	57.5	0	0	0	0	106.9	P111 T115	P111-S113 PolarHBondContact O-N 3.46Å; P111-S113 VanDerWaalsContact O-N 3.13Å; S113-T115 PolarHBondContact O-N 3.44Å
114	H	67.6	Low	72	Confident	179 Å²	179	90.7 Å²	90.7	83%	0.829	46%	0.462	S	S	*	.	S	Bend	trans	-60.8	-13.5	175.6	-74.4	-85.5	0	0	0	112.7	P112	P112-H114 VanDerWaalsContact C-N 3.32Å; P112-H114 PolarHBondContact O-CD2 3.29Å; P112-H114 PolarHBondContact O-N 3.35Å
115	T	76.9	Confident	73.2	Confident	63 Å²	63	85.3 Å²	85.3	39%	0.387	44%	0.444	S	S	.	.	S	Bend	trans	-113.8	147.1	179.7	55.4	0	0	0	0	111.6	T102 S113 L117 F119	T102-T115 PolarHBondContact OG1-O 3.45Å; S113-T115 PolarHBondContact O-N 3.44Å; T115-L117 PolarHBondContact O-N 3.31Å; T115-L117 PolarHBondContact OG1-O 3.46Å; T115-F119 HydrophobicContact CG2-CD2 4.11Å; T115-F119 HydrophobicContact CG2-CE2 3.9Å
116	S	78.3	Confident	74.3	Confident	48 Å²	48	78.9 Å²	78.9	34%	0.336	42%	0.42	S	S	.	.	S	Bend	trans	-70.5	-10.4	176.2	58.1	0	0	0	0	114.7	T102	T102-S116 PolarHBondContact N-O 2.86Å; T102-S116 VanDerWaalsContact OG1-CA 3.31Å; T102-S116 WeakPolarHBondContact OG1-CA 3.49Å; T102-S116 PolarHBondContact OG1-O 3.43Å
117	L	84	Confident	75.9	Confident	13 Å²	13	72.8 Å²	72.8	7%	0.068	40%	0.399	C	S	.	.	B	Isolated β-bridge	trans	-129.9	143.5	179.3	-61.2	176.2	0	0	0	110.7	I97 Y100 T115 F119	I97-L117 HydrophobicContact CB-CD2 4.18Å; I97-L117 HydrophobicContact CG1-CD1 4Å; I97-L117 HydrophobicContact CG1-CD2 4.05Å; I97-L117 HydrophobicContact CG2-CD2 4.17Å; Y100-L117 WeakPolarHBondContact O-CA 3.4Å; T115-L117 PolarHBondContact O-N 3.31Å; T115-L117 PolarHBondContact OG1-O 3.46Å; L117-F119 VanDerWaalsContact C-N 3.28Å; L117-F119 HydrophobicContact CB-CD1 4.46Å; L117-F119 HydrophobicContact CB-CD2 4.43Å; L117-F119 HydrophobicContact CB-CE1 4.15Å; L117-F119 HydrophobicContact CB-CE2 4.14Å; L117-F119 HydrophobicContact CB-CZ 3.99Å; L117-F119 HydrophobicContact CD1-CE1 4.02Å; L117-F119 HydrophobicContact CD1-CZ 4.08Å; L117-F119 WeakPolarHBondContact O-CD2 3.47Å; L117-F119 PolarHBondContact O-N 3.04Å
118	N	83.6	Confident	77.9	Confident	36 Å²	36	71.2 Å²	71.2	19%	0.193	38%	0.384	C	S	.	.			trans	-79	73.7	170.5	-78	-42.3	0	0	0	110.6	Y100 T102 H120 L121	Y100-N118 PolarHBondContact O-N 2.88Å; T102-N118 HydrophobicContact CG2-CB 4.14Å; T102-N118 WeakPolarHBondContact CG2-ND2 3.05Å; T102-N118 WeakPolarHBondContact CG2-OD1 3.48Å; N118-H120 PolarHBondContact O-N 3.23Å; N118-H120 VanDerWaalsContact O-N 3.13Å; N118-H120 PolarHBondContact OD1-CE1 3.42Å; N118-L121 HydrophobicContact CB-CB 4.28Å; N118-L121 HydrophobicContact CB-CD1 3.63Å; N118-L121 HydrophobicContact CB-CG 3.95Å; N118-L121 PolarHBondContact O-N 2.9Å
119	F	86.3	Confident	79.5	Confident	98 Å²	98	68.1 Å²	68.1	43%	0.43	36%	0.363	S	S	.	.	G	3₁₀ helix	trans	-56.4	-30.8	-179.3	-66.7	-70.1	0	0	0	113.7	T115 L117 L121 I122	T115-F119 HydrophobicContact CG2-CD2 4.11Å; T115-F119 HydrophobicContact CG2-CE2 3.9Å; L117-F119 VanDerWaalsContact C-N 3.28Å; L117-F119 HydrophobicContact CB-CD1 4.46Å; L117-F119 HydrophobicContact CB-CD2 4.43Å; L117-F119 HydrophobicContact CB-CE1 4.15Å; L117-F119 HydrophobicContact CB-CE2 4.14Å; L117-F119 HydrophobicContact CB-CZ 3.99Å; L117-F119 HydrophobicContact CD1-CE1 4.02Å; L117-F119 HydrophobicContact CD1-CZ 4.08Å; L117-F119 WeakPolarHBondContact O-CD2 3.47Å; L117-F119 PolarHBondContact O-N 3.04Å; F119-L121 PolarHBondContact O-N 3.49Å; F119-I122 HydrophobicContact CD1-CD1 4.21Å; F119-I122 PolarHBondContact O-N 2.96Å
120	H	84.7	Confident	81.3	Confident	151 Å²	151	62.7 Å²	62.7	70%	0.699	33%	0.326	S	S	*	.	G	3₁₀ helix	trans	-68.5	-18.7	179.1	71.5	-86.2	0	0	0	114	N118	N118-H120 PolarHBondContact O-N 3.23Å; N118-H120 VanDerWaalsContact O-N 3.13Å; N118-H120 PolarHBondContact OD1-CE1 3.42Å
121	L	86.5	Confident	83.4	Confident	51 Å²	51	57.3 Å²	57.3	27%	0.267	30%	0.303	S	S	.	.	G	3₁₀ helix	trans	-88.9	-13.9	176.6	-63.2	176.9	0	0	0	112.6	Y100 N118 F119 D123	Y100-L121 HydrophobicContact CD1-CB 3.56Å; Y100-L121 HydrophobicContact CD1-CD1 4.3Å; Y100-L121 HydrophobicContact CE1-CB 3.57Å; Y100-L121 WeakPolarHBondContact CE1-O 3.31Å; Y100-L121 PolarHBondContact OH-O 3.34Å; N118-L121 HydrophobicContact CB-CB 4.28Å; N118-L121 HydrophobicContact CB-CD1 3.63Å; N118-L121 HydrophobicContact CB-CG 3.95Å; N118-L121 PolarHBondContact O-N 2.9Å; F119-L121 PolarHBondContact O-N 3.49Å; L121-D123 PolarHBondContact O-N 3.44Å
122	I	90	Very high	85.2	Confident	19 Å²	19	53 Å²	53	10%	0.097	27%	0.274	C	S	.	.	S	Bend	trans	-79.3	120.6	-178.1	-63.2	178	0	0	0	109	Y96 Y100 F119 F124	Y96-I122 HydrophobicContact CD1-CD1 4.25Å; Y96-I122 HydrophobicContact CD1-CG1 4.2Å; Y96-I122 HydrophobicContact CD1-CG2 3.98Å; Y96-I122 HydrophobicContact CE1-CG2 3.82Å; Y100-I122 HydrophobicContact CD1-CG1 4.27Å; Y100-I122 HydrophobicContact CD2-CD1 4.17Å; Y100-I122 HydrophobicContact CD2-CG1 3.59Å; Y100-I122 HydrophobicContact CE2-CG1 3.88Å; Y100-I122 HydrophobicContact CG-CD1 4.41Å; Y100-I122 HydrophobicContact CG-CG1 3.77Å; F119-I122 HydrophobicContact CD1-CD1 4.21Å; F119-I122 PolarHBondContact O-N 2.96Å; I122-F124 HydrophobicContact CG2-CE1 4.44Å; I122-F124 PolarHBondContact O-N 2.94Å
123	D	92.3	Very high	87	Confident	22 Å²	22	50.8 Å²	50.8	12%	0.118	26%	0.259	C	S	.	.			trans	-78.2	100.6	169.4	-170.4	-26.3	0	0	0	110.1	L121 N125 L126 L127 Y186	L121-D123 PolarHBondContact O-N 3.44Å; D123-N125 PolarHBondContact O-N 2.98Å; D123-N125 WeakPolarHBondContact OD1-CA 3.34Å; D123-N125 WeakPolarHBondContact OD1-CB 3.39Å; D123-N125 PolarHBondContact OD1-N 3.05Å; D123-L126 HydrophobicContact CB-CB 3.94Å; D123-L126 PolarHBondContact O-N 3.22Å; D123-L126 PolarHBondContact OD1-N 3.19Å; D123-L126 VanDerWaalsContact OD1-N 3.16Å; D123-L127 PolarHBondContact O-N 3.01Å; D123-Y186 VanDerWaalsContact OD2-CE2 3.23Å; D123-Y186 WeakPolarHBondContact OD2-CE2 3.5Å; D123-Y186 PolarHBondContact OD2-OH 3.3Å
124	F	93.3	Very high	88.5	Confident	124 Å²	124	49.5 Å²	49.5	54%	0.544	25%	0.249	S	C	.	.	H	α-helix	trans	-63.7	-27.1	178.8	-69.8	-76.7	0	0	0	113.3	I122 L127 M128	I122-F124 HydrophobicContact CG2-CE1 4.44Å; I122-F124 PolarHBondContact O-N 2.94Å; F124-L127 HydrophobicContact CD1-CD2 4.44Å; F124-M128 VanDerWaalsContact O-CB 3.23Å; F124-M128 WeakPolarHBondContact O-CB 3.27Å; F124-M128 PolarHBondContact O-N 3.47Å
125	N	93.8	Very high	89.6	Confident	28 Å²	28	41.1 Å²	41.1	15%	0.15	21%	0.211	C	C	.	.	H	α-helix	trans	-72.5	-41.3	177.5	-64.4	-72	0	0	0	110.7	D123 M128 V129 S178 H181 L182	D123-N125 PolarHBondContact O-N 2.98Å; D123-N125 WeakPolarHBondContact OD1-CA 3.34Å; D123-N125 WeakPolarHBondContact OD1-CB 3.39Å; D123-N125 PolarHBondContact OD1-N 3.05Å; N125-M128 PolarHBondContact O-N 3.39Å; N125-V129 WeakPolarHBondContact O-CG2 3.29Å; N125-V129 PolarHBondContact O-N 3.4Å; N125-S178 PolarHBondContact OD1-OG 3.33Å; N125-H181 HydrophobicContact CB-CB 4.45Å; N125-H181 PolarHBondContact ND2-CE1 3.3Å; N125-H181 VanDerWaalsContact ND2-CG 3.29Å; N125-H181 PolarHBondContact ND2-ND1 3.01Å; N125-H181 VanDerWaalsContact ND2-ND1 3.1Å; N125-L182 HydrophobicContact CB-CD2 4.49Å; N125-L182 HydrophobicContact CB-CG 4.35Å
126	L	93.8	Very high	90.1	Very high	2 Å²	2	41.6 Å²	41.6	1%	0.01	21%	0.206	C	C	.	.	H	α-helix	trans	-62.4	-45.7	173	-179.2	68.8	0	0	0	111.5	D123 M128 V129 T130 L182 L194 V303 F307	D123-L126 HydrophobicContact CB-CB 3.94Å; D123-L126 PolarHBondContact O-N 3.22Å; D123-L126 PolarHBondContact OD1-N 3.19Å; D123-L126 VanDerWaalsContact OD1-N 3.16Å; L126-M128 VanDerWaalsContact C-N 3.26Å; L126-M128 PolarHBondContact O-N 2.91Å; L126-V129 PolarHBondContact O-N 3.33Å; L126-T130 WeakPolarHBondContact O-CB 3.26Å; L126-T130 PolarHBondContact O-N 2.88Å; L126-T130 PolarHBondContact O-OG1 3.34Å; L126-L182 HydrophobicContact CB-CD2 4.18Å; L126-L194 HydrophobicContact CD1-CD1 4.32Å; L126-L194 HydrophobicContact CD1-CD2 3.89Å; L126-V303 HydrophobicContact CD1-CG1 3.96Å; L126-F307 HydrophobicContact CD1-CD1 4.41Å; L126-F307 HydrophobicContact CD1-CD2 3.75Å; L126-F307 HydrophobicContact CD1-CE2 3.94Å; L126-F307 HydrophobicContact CD1-CG 4.02Å; L126-F307 HydrophobicContact CD1-CZ 4.36Å; L126-F307 HydrophobicContact CD2-CB 3.34Å; L126-F307 HydrophobicContact CD2-CD1 4.42Å; L126-F307 HydrophobicContact CD2-CD2 3.89Å; L126-F307 HydrophobicContact CD2-CG 3.64Å; L126-F307 HydrophobicContact CG-CD2 4.49Å; L126-F307 HydrophobicContact CG-CG 4.48Å
127	L	95	Very high	90.4	Very high	44 Å²	44	40.2 Å²	40.2	23%	0.23	19%	0.193	C	C	.	.	H	α-helix	trans	-58.9	-41.4	177	179	63	0	0	0	111.1	L92 Y96 D123 F124 T130 T131	L92-L127 HydrophobicContact CD2-CD1 3.71Å; L92-L127 HydrophobicContact CG-CD1 4.16Å; Y96-L127 HydrophobicContact CD2-CD1 4.17Å; Y96-L127 HydrophobicContact CE1-CD1 4.43Å; Y96-L127 HydrophobicContact CE2-CD1 3.66Å; D123-L127 PolarHBondContact O-N 3.01Å; F124-L127 HydrophobicContact CD1-CD2 4.44Å; L127-T130 PolarHBondContact O-N 3Å; L127-T131 VanDerWaalsContact O-CB 3.29Å; L127-T131 WeakPolarHBondContact O-CB 3.42Å; L127-T131 PolarHBondContact O-N 2.94Å; L127-T131 PolarHBondContact O-OG1 3.38Å
128	M	94	Very high	90.6	Very high	62 Å²	62	41.6 Å²	41.6	31%	0.305	20%	0.199	S	C	.	.	H	α-helix	trans	-66	-45.6	178.2	-170.3	153.3	79	0	0	112.2	F124 N125 L126 T130 T131 I132 S174 S178	F124-M128 VanDerWaalsContact O-CB 3.23Å; F124-M128 WeakPolarHBondContact O-CB 3.27Å; F124-M128 PolarHBondContact O-N 3.47Å; N125-M128 PolarHBondContact O-N 3.39Å; L126-M128 VanDerWaalsContact C-N 3.26Å; L126-M128 PolarHBondContact O-N 2.91Å; M128-T130 PolarHBondContact O-N 3.11Å; M128-T131 PolarHBondContact O-N 3.06Å; M128-I132 HydrophobicContact CG-CD1 3.97Å; M128-I132 WeakPolarHBondContact O-CB 3.36Å; M128-I132 VanDerWaalsContact O-CG1 3.24Å; M128-I132 WeakPolarHBondContact O-CG1 3.43Å; M128-I132 PolarHBondContact O-N 2.89Å; M128-S174 WeakPolarHBondContact CE-OG 3.48Å; M128-S174 WeakPolarHBondContact CG-OG 3.44Å; M128-S174 PolarHBondContact SD-OG 3.1Å; M128-S178 WeakPolarHBondContact CE-OG 3.16Å
129	V	93.7	Very high	90.7	Very high	5 Å²	5	41.3 Å²	41.3	3%	0.03	20%	0.197	C	C	.	.	H	α-helix	trans	-60	-47.7	174.6	170.8	0	0	0	0	111	N125 L126 T131 I132 V133 L175 L179 L182	N125-V129 WeakPolarHBondContact O-CG2 3.29Å; N125-V129 PolarHBondContact O-N 3.4Å; L126-V129 PolarHBondContact O-N 3.33Å; V129-T131 VanDerWaalsContact C-N 3.32Å; V129-T131 PolarHBondContact O-N 3.36Å; V129-I132 PolarHBondContact O-N 3.32Å; V129-V133 HydrophobicContact CG1-CG2 4.36Å; V129-V133 VanDerWaalsContact O-CG2 3.31Å; V129-V133 WeakPolarHBondContact O-CG2 3.5Å; V129-V133 PolarHBondContact O-N 2.85Å; V129-L175 HydrophobicContact CG1-CD1 4.32Å; V129-L175 HydrophobicContact CG2-CD1 4.19Å; V129-L179 HydrophobicContact CG2-CD2 4.29Å; V129-L179 HydrophobicContact CG2-CG 4.48Å; V129-L182 HydrophobicContact CB-CD1 4.33Å; V129-L182 HydrophobicContact CG2-CD1 3.67Å
130	T	94	Very high	90.5	Very high	0 Å²	0	38.4 Å²	38.4	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-59.2	-45.2	179.5	-55.9	0	0	0	0	111	L92 L126 L127 M128 V133 L134 Y299	L92-T130 HydrophobicContact CD1-CG2 3.85Å; L92-T130 HydrophobicContact CD2-CG2 4.14Å; L126-T130 WeakPolarHBondContact O-CB 3.26Å; L126-T130 PolarHBondContact O-N 2.88Å; L126-T130 PolarHBondContact O-OG1 3.34Å; L127-T130 PolarHBondContact O-N 3Å; M128-T130 PolarHBondContact O-N 3.11Å; T130-V133 PolarHBondContact O-N 3.41Å; T130-L134 HydrophobicContact CG2-CD1 4.14Å; T130-L134 VanDerWaalsContact O-CG 3.31Å; T130-L134 WeakPolarHBondContact O-CG 3.28Å; T130-L134 PolarHBondContact O-N 2.87Å; T130-Y299 HydrophobicContact CG2-CD1 4.27Å; T130-Y299 WeakPolarHBondContact CG2-O 3.36Å
131	T	94.4	Very high	90.3	Very high	39 Å²	39	31.3 Å²	31.3	24%	0.239	16%	0.162	C	C	.	.	H	α-helix	trans	-63.1	-43.6	177.4	-61.2	0	0	0	0	112.2	F85 L89 L127 M128 V129 L134 G135	F85-T131 HydrophobicContact CE2-CG2 4.31Å; F85-T131 HydrophobicContact CZ-CG2 3.99Å; L89-T131 HydrophobicContact CD2-CG2 3.83Å; L127-T131 VanDerWaalsContact O-CB 3.29Å; L127-T131 WeakPolarHBondContact O-CB 3.42Å; L127-T131 PolarHBondContact O-N 2.94Å; L127-T131 PolarHBondContact O-OG1 3.38Å; M128-T131 PolarHBondContact O-N 3.06Å; V129-T131 VanDerWaalsContact C-N 3.32Å; V129-T131 PolarHBondContact O-N 3.36Å; T131-L134 PolarHBondContact O-N 3.33Å; T131-G135 PolarHBondContact O-N 3.39Å
132	I	92.4	Very high	90.2	Very high	28 Å²	28	30.7 Å²	30.7	14%	0.144	16%	0.158	C	C	.	.	H	α-helix	trans	-64.9	-41	177.9	-69.1	166.6	0	0	0	110.8	M128 V129 G135 R136 L175	M128-I132 HydrophobicContact CG-CD1 3.97Å; M128-I132 WeakPolarHBondContact O-CB 3.36Å; M128-I132 VanDerWaalsContact O-CG1 3.24Å; M128-I132 WeakPolarHBondContact O-CG1 3.43Å; M128-I132 PolarHBondContact O-N 2.89Å; V129-I132 PolarHBondContact O-N 3.32Å; I132-G135 CarbonylContact O-C 3.59Å; I132-G135 PolarHBondContact O-N 3.41Å; I132-R136 PolarHBondContact O-N 2.86Å; I132-L175 HydrophobicContact CB-CD1 4.46Å; I132-L175 HydrophobicContact CD1-CB 4.12Å; I132-L175 HydrophobicContact CD1-CD1 4.41Å; I132-L175 HydrophobicContact CG2-CD1 4.12Å
133	V	91.1	Very high	89.8	Confident	18 Å²	18	31.6 Å²	31.6	11%	0.109	17%	0.165	C	C	.	.	H	α-helix	trans	-66.5	-43.1	178.9	173.3	0	0	0	0	111.6	V129 T130 G135 R136 F198 Y299	V129-V133 HydrophobicContact CG1-CG2 4.36Å; V129-V133 VanDerWaalsContact O-CG2 3.31Å; V129-V133 WeakPolarHBondContact O-CG2 3.5Å; V129-V133 PolarHBondContact O-N 2.85Å; T130-V133 PolarHBondContact O-N 3.41Å; V133-G135 VanDerWaalsContact C-N 3.32Å; V133-R136 VanDerWaalsContact O-CB 3.3Å; V133-R136 WeakPolarHBondContact O-CB 3.38Å; V133-R136 WeakPolarHBondContact O-CD 3.41Å; V133-R136 WeakPolarHBondContact O-CG 3.34Å; V133-R136 PolarHBondContact O-N 3.37Å; V133-F198 HydrophobicContact CG1-CE2 4.22Å; V133-F198 HydrophobicContact CG1-CZ 3.76Å; V133-Y299 HydrophobicContact CB-CE1 4.35Å; V133-Y299 HydrophobicContact CB-CE2 4.42Å; V133-Y299 HydrophobicContact CG1-CD1 4.33Å; V133-Y299 HydrophobicContact CG1-CD2 3.71Å; V133-Y299 HydrophobicContact CG1-CE1 4.03Å; V133-Y299 HydrophobicContact CG1-CE2 3.31Å; V133-Y299 HydrophobicContact CG1-CG 4.21Å; V133-Y299 HydrophobicContact CG2-CE1 4.47Å
134	L	92.2	Very high	88.9	Confident	10 Å²	10	33.3 Å²	33.3	5%	0.052	17%	0.171	C	C	.	.	H	α-helix	trans	-62.7	-41.5	172.9	-69.3	171.3	0	0	0	111.1	F85 Q88 L92 T130 T131 R136 V300	F85-L134 HydrophobicContact CE2-CB 4.43Å; Q88-L134 HydrophobicContact CB-CD1 4.39Å; L92-L134 HydrophobicContact CD2-CD1 4.19Å; T130-L134 HydrophobicContact CG2-CD1 4.14Å; T130-L134 VanDerWaalsContact O-CG 3.31Å; T130-L134 WeakPolarHBondContact O-CG 3.28Å; T130-L134 PolarHBondContact O-N 2.87Å; T131-L134 PolarHBondContact O-N 3.33Å; L134-R136 PolarHBondContact O-N 3.28Å; L134-V300 HydrophobicContact CD1-CG2 3.77Å; L134-V300 HydrophobicContact CD2-CG2 4.12Å
135	G	90.5	Very high	88.1	Confident	2 Å²	2	31.3 Å²	31.3	2%	0.021	16%	0.163	C	C	.	.	T	Hydrogen-bonded Turn	trans	-71.8	-4.2	177.8	0	0	0	0	0	115.3	T131 I132 V133 R137 F138 I139	T131-G135 PolarHBondContact O-N 3.39Å; I132-G135 CarbonylContact O-C 3.59Å; I132-G135 PolarHBondContact O-N 3.41Å; V133-G135 VanDerWaalsContact C-N 3.32Å; G135-R137 PolarHBondContact O-N 3.42Å; G135-R137 VanDerWaalsContact O-N 3.14Å; G135-F138 PolarHBondContact O-N 3.18Å; G135-F138 VanDerWaalsContact O-N 3.1Å; G135-I139 VanDerWaalsContact O-CG1 3.31Å; G135-I139 WeakPolarHBondContact O-CG1 3.49Å; G135-I139 PolarHBondContact O-N 2.87Å
136	R	88.2	Confident	86.9	Confident	74 Å²	74	30.9 Å²	30.9	28%	0.279	16%	0.164	S	C	.	.	H	α-helix	trans	-53.4	-40.1	-175.7	74.4	-174.6	176.1	86.5	-0.3	113.2	I132 V133 L134 G140 Y201 L295	I132-R136 PolarHBondContact O-N 2.86Å; V133-R136 VanDerWaalsContact O-CB 3.3Å; V133-R136 WeakPolarHBondContact O-CB 3.38Å; V133-R136 WeakPolarHBondContact O-CD 3.41Å; V133-R136 WeakPolarHBondContact O-CG 3.34Å; V133-R136 PolarHBondContact O-N 3.37Å; L134-R136 PolarHBondContact O-N 3.28Å; R136-G140 PolarHBondContact O-N 3.24Å; R136-Y201 PolarHBondContact NH2-OH 3.5Å; R136-L295 VanDerWaalsContact NH2-CD2 3.31Å
137	R	85	Confident	85.7	Confident	19 Å²	19	34.6 Å²	34.6	7%	0.072	19%	0.19	C	C	.	.	H	α-helix	trans	-72.9	-41.5	-177.7	-64	175.9	55.4	144.5	-0.5	111.1	E81 G135 G140 S141	E81-R137 IonicContact OE1-CZ 3.27Å; E81-R137 VanDerWaalsContact OE1-CZ 3.27Å; E81-R137 IonicContact OE1-NE 2.91Å; E81-R137 PolarHBondContact OE1-NE 3.48Å; E81-R137 IonicContact OE1-NH2 2.78Å; E81-R137 PolarHBondContact OE1-NH2 2.99Å; E81-R137 WeakPolarHBondContact OE2-CB 3.48Å; E81-R137 IonicContact OE2-CZ 3.86Å; E81-R137 IonicContact OE2-NE 3.09Å; E81-R137 PolarHBondContact OE2-NE 3.22Å; E81-R137 VanDerWaalsContact OE2-NE 3.09Å; E81-R137 IonicContact OE2-NH2 3.86Å; G135-R137 PolarHBondContact O-N 3.42Å; G135-R137 VanDerWaalsContact O-N 3.14Å; R137-G140 PolarHBondContact O-N 2.96Å; R137-S141 PolarHBondContact O-N 3.04Å
138	F	87.3	Confident	84.3	Confident	41 Å²	41	38.5 Å²	38.5	18%	0.18	21%	0.207	C	C	.	.	H	α-helix	trans	-63.7	-47.6	174.9	177.5	-122.6	0	0	0	112	I78 E81 L82 F85 G135 G140 S141 I142	I78-F138 HydrophobicContact CG1-CE2 4.25Å; E81-F138 HydrophobicContact CB-CB 4.34Å; E81-F138 HydrophobicContact CB-CD2 4.22Å; L82-F138 HydrophobicContact CB-CD2 4.15Å; L82-F138 HydrophobicContact CB-CE2 3.76Å; L82-F138 HydrophobicContact CB-CZ 4.47Å; L82-F138 HydrophobicContact CD1-CE1 4.28Å; L82-F138 HydrophobicContact CD1-CE2 3.83Å; L82-F138 HydrophobicContact CD1-CZ 3.66Å; L82-F138 HydrophobicContact CG-CE2 4.34Å; F85-F138 HydrophobicContact CB-CB 4.2Å; F85-F138 AromaticContact CD1-CD1 3.84Å; F85-F138 HydrophobicContact CD1-CD1 3.84Å; F85-F138 HydrophobicContact CD1-CE1 4.35Å; F85-F138 HydrophobicContact CD1-CG 4.35Å; F85-F138 HydrophobicContact CE1-CD1 4.21Å; F85-F138 HydrophobicContact CG-CB 4.37Å; F85-F138 HydrophobicContact CG-CD1 4.45Å; G135-F138 PolarHBondContact O-N 3.18Å; G135-F138 VanDerWaalsContact O-N 3.1Å; F138-G140 VanDerWaalsContact C-N 3.31Å; F138-G140 PolarHBondContact O-N 2.92Å; F138-S141 WeakPolarHBondContact O-CB 3.33Å; F138-S141 PolarHBondContact O-N 3.32Å; F138-S141 VanDerWaalsContact O-N 3.09Å; F138-I142 HydrophobicContact CD1-CD1 4.08Å; F138-I142 HydrophobicContact CD2-CD1 4.44Å; F138-I142 HydrophobicContact CD2-CG1 4.46Å; F138-I142 HydrophobicContact CE1-CD1 3.62Å; F138-I142 HydrophobicContact CE2-CD1 4Å; F138-I142 HydrophobicContact CE2-CG1 4.08Å; F138-I142 HydrophobicContact CG-CD1 4.47Å; F138-I142 HydrophobicContact CZ-CD1 3.58Å; F138-I142 HydrophobicContact CZ-CG1 4.15Å; F138-I142 WeakPolarHBondContact O-CG1 3.32Å; F138-I142 PolarHBondContact O-N 3Å
139	I	86.4	Confident	82.3	Confident	30 Å²	30	47.4 Å²	47.4	15%	0.154	24%	0.237	C	C	.	.	H	α-helix	trans	-58	-45.6	174.8	-64.4	161.2	0	0	0	110.3	G135 S141 I142 V143 V167 T171	G135-I139 VanDerWaalsContact O-CG1 3.31Å; G135-I139 WeakPolarHBondContact O-CG1 3.49Å; G135-I139 PolarHBondContact O-N 2.87Å; I139-S141 VanDerWaalsContact C-N 3.32Å; I139-S141 PolarHBondContact O-N 2.92Å; I139-I142 PolarHBondContact O-N 3.09Å; I139-V143 WeakPolarHBondContact O-CG2 3.4Å; I139-V143 PolarHBondContact O-N 2.82Å; I139-V167 HydrophobicContact CG2-CG1 4.05Å; I139-T171 HydrophobicContact CD1-CG2 3.8Å; I139-T171 HydrophobicContact CG1-CG2 4.37Å
140	G	81.2	Confident	80.6	Confident	37 Å²	37	49.4 Å²	49.4	38%	0.381	26%	0.259	S	S	.	.	H	α-helix	trans	-59.2	-40.2	175.2	0	0	0	0	0	113.2	R136 R137 F138 V143 K144	R136-G140 PolarHBondContact O-N 3.24Å; R137-G140 PolarHBondContact O-N 2.96Å; F138-G140 VanDerWaalsContact C-N 3.31Å; F138-G140 PolarHBondContact O-N 2.92Å; G140-V143 PolarHBondContact O-N 2.83Å; G140-K144 WeakPolarHBondContact O-CB 3.47Å; G140-K144 PolarHBondContact O-N 2.74Å
141	S	82	Confident	78.6	Confident	2 Å²	2	60.1 Å²	60.1	1%	0.014	31%	0.306	C	S	.	.	H	α-helix	trans	-66.7	-41.8	176.3	-169.4	0	0	0	0	112.5	I78 R137 F138 I139 V143 K144 E145	I78-S141 WeakPolarHBondContact CA-OG 3.28Å; R137-S141 PolarHBondContact O-N 3.04Å; F138-S141 WeakPolarHBondContact O-CB 3.33Å; F138-S141 PolarHBondContact O-N 3.32Å; F138-S141 VanDerWaalsContact O-N 3.09Å; I139-S141 VanDerWaalsContact C-N 3.32Å; I139-S141 PolarHBondContact O-N 2.92Å; S141-V143 VanDerWaalsContact C-N 3.33Å; S141-V143 PolarHBondContact O-N 3.19Å; S141-K144 PolarHBondContact O-N 3.27Å; S141-E145 WeakPolarHBondContact O-CB 3.36Å; S141-E145 PolarHBondContact O-N 2.85Å
142	I	82.9	Confident	76.8	Confident	38 Å²	38	61.1 Å²	61.1	20%	0.195	31%	0.312	C	S	.	.	H	α-helix	trans	-59.3	-47.3	175	-67	167.8	0	0	0	110.1	I78 F138 I139 K144 E145 A146	I78-I142 HydrophobicContact CD1-CG1 3.97Å; F138-I142 HydrophobicContact CD1-CD1 4.08Å; F138-I142 HydrophobicContact CD2-CD1 4.44Å; F138-I142 HydrophobicContact CD2-CG1 4.46Å; F138-I142 HydrophobicContact CE1-CD1 3.62Å; F138-I142 HydrophobicContact CE2-CD1 4Å; F138-I142 HydrophobicContact CE2-CG1 4.08Å; F138-I142 HydrophobicContact CG-CD1 4.47Å; F138-I142 HydrophobicContact CZ-CD1 3.58Å; F138-I142 HydrophobicContact CZ-CG1 4.15Å; F138-I142 WeakPolarHBondContact O-CG1 3.32Å; F138-I142 PolarHBondContact O-N 3Å; I139-I142 PolarHBondContact O-N 3.09Å; I142-K144 VanDerWaalsContact C-N 3.29Å; I142-K144 PolarHBondContact O-N 2.88Å; I142-E145 PolarHBondContact O-N 3.48Å; I142-A146 WeakPolarHBondContact O-CB 3.27Å; I142-A146 PolarHBondContact O-N 2.91Å
143	V	81.5	Confident	76	Confident	39 Å²	39	63.5 Å²	63.5	24%	0.236	33%	0.331	C	S	.	.	H	α-helix	trans	-63.2	-36.9	179.9	173.7	0	0	0	0	111.3	I139 G140 S141 S147 R164	I139-V143 WeakPolarHBondContact O-CG2 3.4Å; I139-V143 PolarHBondContact O-N 2.82Å; G140-V143 PolarHBondContact O-N 2.83Å; S141-V143 VanDerWaalsContact C-N 3.33Å; S141-V143 PolarHBondContact O-N 3.19Å; V143-S147 PolarHBondContact O-N 3.37Å; V143-R164 HydrophobicContact CG1-CG 4.46Å
144	K	74.7	Confident	75.3	Confident	58 Å²	58	69.9 Å²	69.9	25%	0.252	36%	0.364	S	S	.	.	H	α-helix	trans	-71.1	-45.6	177.9	-174.2	176.6	-172.8	168.3	0	112.5	G140 S141 I142 A146 S147 Q148 T250 Y254	G140-K144 WeakPolarHBondContact O-CB 3.47Å; G140-K144 PolarHBondContact O-N 2.74Å; S141-K144 PolarHBondContact O-N 3.27Å; I142-K144 VanDerWaalsContact C-N 3.29Å; I142-K144 PolarHBondContact O-N 2.88Å; K144-A146 VanDerWaalsContact C-N 3.27Å; K144-A146 PolarHBondContact O-N 3.33Å; K144-S147 WeakPolarHBondContact O-CA 3.28Å; K144-S147 WeakPolarHBondContact O-CB 3.4Å; K144-S147 PolarHBondContact O-N 3.47Å; K144-Q148 PolarHBondContact O-N 3.46Å; K144-T250 PolarHBondContact NZ-O 2.86Å; K144-T250 VanDerWaalsContact NZ-O 3.15Å; K144-Y254 WeakPolarHBondContact CE-O 3.32Å; K144-Y254 VanDerWaalsContact NZ-C 3.31Å; K144-Y254 PolarHBondContact NZ-O 3.29Å
145	E	75.9	Confident	74.8	Confident	81 Å²	81	77 Å²	77	38%	0.379	40%	0.395	S	S	.	.	H	α-helix	trans	-60.1	-42.1	178.3	-169.1	60.7	-158.2	0	0	110.6	I78 S141 I142 S147 Q148	I78-E145 HydrophobicContact CD1-CB 4.28Å; I78-E145 HydrophobicContact CD1-CG 4.43Å; S141-E145 WeakPolarHBondContact O-CB 3.36Å; S141-E145 PolarHBondContact O-N 2.85Å; I142-E145 PolarHBondContact O-N 3.48Å; E145-S147 PolarHBondContact O-N 2.93Å; E145-Q148 PolarHBondContact O-N 2.65Å; E145-Q148 PolarHBondContact OE2-NE2 2.95Å
146	A	69.8	Low	74.3	Confident	20 Å²	20	83.9 Å²	83.9	17%	0.165	42%	0.42	C	S	.	.	T	Hydrogen-bonded Turn	trans	-65.2	-16.7	173.4	0	0	0	0	0	114.3	I142 K144 L160	I142-A146 WeakPolarHBondContact O-CB 3.27Å; I142-A146 PolarHBondContact O-N 2.91Å; K144-A146 VanDerWaalsContact C-N 3.27Å; K144-A146 PolarHBondContact O-N 3.33Å; A146-L160 HydrophobicContact CB-CB 4.28Å; A146-L160 HydrophobicContact CB-CD2 3.85Å
147	S	68.5	Low	73.8	Confident	79 Å²	79	83.7 Å²	83.7	55%	0.552	43%	0.43	S	S	*	.	T	Hydrogen-bonded Turn	trans	-93.8	-10.7	-178.3	-175.1	0	0	0	0	113.9	V143 K144 E145 R149	V143-S147 PolarHBondContact O-N 3.37Å; K144-S147 WeakPolarHBondContact O-CA 3.28Å; K144-S147 WeakPolarHBondContact O-CB 3.4Å; K144-S147 PolarHBondContact O-N 3.47Å; E145-S147 PolarHBondContact O-N 2.93Å; S147-R149 PolarHBondContact O-N 2.92Å
148	Q	65.5	Low	73.7	Confident	127 Å²	127	88.3 Å²	88.3	59%	0.593	46%	0.455	S	S	*	.			trans	-61.8	113.3	-178	-67	-166.5	15	0	0	109.9	K144 E145 G150	K144-Q148 PolarHBondContact O-N 3.46Å; E145-Q148 PolarHBondContact O-N 2.65Å; E145-Q148 PolarHBondContact OE2-NE2 2.95Å; Q148-G150 PolarHBondContact O-N 3.33Å
149	R	51.5	Low	73.5	Confident	248 Å²	248	90.7 Å²	90.7	94%	0.936	47%	0.469	S	S	*	.			trans	-73.1	51.7	-175.4	-73	179.1	167.6	-128.8	-0.4	112.2	S147	S147-R149 PolarHBondContact O-N 2.92Å
150	G	57	Low	73.3	Confident	48 Å²	48	91.6 Å²	91.6	50%	0.495	47%	0.474	S	S	.	.			trans	-62.9	143	163.4	0	0	0	0	0	109.1	Q148 V152	Q148-G150 PolarHBondContact O-N 3.33Å; G150-V152 WeakPolarHBondContact O-CB 3.35Å; G150-V152 WeakPolarHBondContact O-CG2 3.4Å; G150-V152 PolarHBondContact O-N 2.9Å
151	K	52.2	Low	73.3	Confident	224 Å²	224	96.5 Å²	96.5	97%	0.974	49%	0.485	S	S	*	.			trans	-60.4	86.2	165.5	-68.1	176.1	-178.4	176.6	0	108
152	V	57.6	Low	73.4	Confident	60 Å²	60	101 Å²	101	36%	0.364	51%	0.509	S	S	.	.			trans	-119	144.9	-169.4	170.2	0	0	0	0	108.9	G150 R156	G150-V152 WeakPolarHBondContact O-CB 3.35Å; G150-V152 WeakPolarHBondContact O-CG2 3.4Å; G150-V152 PolarHBondContact O-N 2.9Å; V152-R156 HydrophobicContact CG1-CB 3.49Å; V152-R156 VanDerWaalsContact CG1-CB 3.49Å; V152-R156 VanDerWaalsContact CG1-CD 3.47Å; V152-R156 HydrophobicContact CG1-CG 3.52Å
153	S	75.9	Confident	73.3	Confident	79 Å²	79	101.8 Å²	101.8	55%	0.552	52%	0.515	S	S	*	.			trans	-53.2	146.1	-178.8	64.2	0	0	0	0	112.7	F155 R156 S157	S153-F155 PolarHBondContact O-N 2.79Å; S153-F155 VanDerWaalsContact O-N 3.11Å; S153-R156 PolarHBondContact O-N 2.92Å; S153-S157 PolarHBondContact O-N 3.38Å
154	L	76.3	Confident	73.3	Confident	151 Å²	151	106.1 Å²	106.1	79%	0.791	53%	0.527	S	S	*	.	H	α-helix	trans	-48.3	-41.4	-178.8	-70.4	173.4	0	0	0	112.6	R156 S157 I158	L154-R156 PolarHBondContact O-N 3.33Å; L154-S157 WeakPolarHBondContact O-CB 3.48Å; L154-S157 PolarHBondContact O-N 3.16Å; L154-I158 WeakPolarHBondContact O-CG1 3.49Å; L154-I158 PolarHBondContact O-N 3.1Å
155	F	80.4	Confident	73.7	Confident	160 Å²	160	109 Å²	109	70%	0.702	54%	0.54	S	S	*	.	H	α-helix	trans	-59.1	-47.9	179.3	-179.2	-103.2	0	0	0	113	S153 S157 I158 L159	S153-F155 PolarHBondContact O-N 2.79Å; S153-F155 VanDerWaalsContact O-N 3.11Å; F155-S157 VanDerWaalsContact C-N 3.34Å; F155-S157 PolarHBondContact O-N 3.35Å; F155-I158 PolarHBondContact O-N 2.91Å; F155-L159 PolarHBondContact O-N 2.9Å
156	R	79.8	Confident	74.3	Confident	146 Å²	146	108.6 Å²	108.6	55%	0.551	54%	0.543	S	S	*	.	H	α-helix	trans	-70.9	-31.8	-179.9	177.9	170.4	176.3	-162.3	5	111.3	V152 S153 L154 L159 L160	V152-R156 HydrophobicContact CG1-CB 3.49Å; V152-R156 VanDerWaalsContact CG1-CB 3.49Å; V152-R156 VanDerWaalsContact CG1-CD 3.47Å; V152-R156 HydrophobicContact CG1-CG 3.52Å; S153-R156 PolarHBondContact O-N 2.92Å; L154-R156 PolarHBondContact O-N 3.33Å; R156-L159 PolarHBondContact O-N 3.11Å; R156-L160 HydrophobicContact CG-CD1 4.25Å; R156-L160 HydrophobicContact CG-CG 4.43Å; R156-L160 WeakPolarHBondContact O-CB 3.42Å; R156-L160 WeakPolarHBondContact O-CG 3.44Å; R156-L160 PolarHBondContact O-N 2.77Å
157	S	78.1	Confident	75.1	Confident	71 Å²	71	109.3 Å²	109.3	50%	0.497	55%	0.546	S	S	.	.	H	α-helix	trans	-62.1	-45.5	171.7	-172.6	0	0	0	0	112.4	S153 L154 F155 L160 F161	S153-S157 PolarHBondContact O-N 3.38Å; L154-S157 WeakPolarHBondContact O-CB 3.48Å; L154-S157 PolarHBondContact O-N 3.16Å; F155-S157 VanDerWaalsContact C-N 3.34Å; F155-S157 PolarHBondContact O-N 3.35Å; S157-L160 PolarHBondContact O-N 3.34Å; S157-F161 PolarHBondContact O-N 3.47Å
158	I	82.5	Confident	76	Confident	115 Å²	115	110.1 Å²	110.1	59%	0.59	54%	0.543	S	S	*	.	H	α-helix	trans	-62	-45.3	176.2	-66.7	165.6	0	0	0	110.6	L154 F155 L160 F161 L162	L154-I158 WeakPolarHBondContact O-CG1 3.49Å; L154-I158 PolarHBondContact O-N 3.1Å; F155-I158 PolarHBondContact O-N 2.91Å; I158-L160 VanDerWaalsContact C-N 3.34Å; I158-L160 PolarHBondContact O-N 2.93Å; I158-F161 PolarHBondContact O-N 2.9Å; I158-L162 WeakPolarHBondContact O-CB 3.29Å; I158-L162 PolarHBondContact O-N 2.85Å
159	L	83.4	Confident	77.1	Confident	92 Å²	92	107 Å²	107	48%	0.482	53%	0.533	S	S	.	.	H	α-helix	trans	-60.1	-42.5	177.7	-175	68.3	0	0	0	112.1	F155 R156 L162 T163	F155-L159 PolarHBondContact O-N 2.9Å; R156-L159 PolarHBondContact O-N 3.11Å; L159-L162 PolarHBondContact O-N 3.47Å; L159-T163 WeakPolarHBondContact O-CB 3.41Å; L159-T163 PolarHBondContact O-N 2.88Å; L159-T163 PolarHBondContact O-OG1 3.15Å
160	L	81.6	Confident	79	Confident	49 Å²	49	97.7 Å²	97.7	26%	0.257	51%	0.509	S	S	.	.	H	α-helix	trans	-66.4	-39.9	177.2	-70.3	174.9	0	0	0	112	A146 R156 S157 I158 T163 R164	A146-L160 HydrophobicContact CB-CB 4.28Å; A146-L160 HydrophobicContact CB-CD2 3.85Å; R156-L160 HydrophobicContact CG-CD1 4.25Å; R156-L160 HydrophobicContact CG-CG 4.43Å; R156-L160 WeakPolarHBondContact O-CB 3.42Å; R156-L160 WeakPolarHBondContact O-CG 3.44Å; R156-L160 PolarHBondContact O-N 2.77Å; S157-L160 PolarHBondContact O-N 3.34Å; I158-L160 VanDerWaalsContact C-N 3.34Å; I158-L160 PolarHBondContact O-N 2.93Å; L160-T163 PolarHBondContact O-N 3.38Å; L160-R164 WeakPolarHBondContact O-CB 3.39Å; L160-R164 PolarHBondContact O-N 3.13Å
161	F	81.2	Confident	80.5	Confident	139 Å²	139	97 Å²	97	61%	0.61	50%	0.495	S	S	*	.	H	α-helix	trans	-62.9	-47.4	174.5	179.5	-95	0	0	0	111.8	S157 I158 T163 R164 F165	S157-F161 PolarHBondContact O-N 3.47Å; I158-F161 PolarHBondContact O-N 2.9Å; F161-T163 VanDerWaalsContact C-N 3.33Å; F161-T163 PolarHBondContact O-N 2.97Å; F161-R164 PolarHBondContact O-N 3.39Å; F161-F165 PolarHBondContact O-N 3.41Å
162	L	85	Confident	82.4	Confident	98 Å²	98	88 Å²	88	51%	0.513	47%	0.466	S	S	.	.	H	α-helix	trans	-63	-40.8	177.9	-175.5	61.6	0	0	0	111.5	I158 L159 F165 T166	I158-L162 WeakPolarHBondContact O-CB 3.29Å; I158-L162 PolarHBondContact O-N 2.85Å; L159-L162 PolarHBondContact O-N 3.47Å; L162-F165 PolarHBondContact O-N 3.25Å; L162-T166 VanDerWaalsContact O-CB 3.29Å; L162-T166 WeakPolarHBondContact O-CB 3.23Å; L162-T166 PolarHBondContact O-N 3.15Å; L162-T166 PolarHBondContact O-OG1 3.28Å
163	T	82	Confident	84.1	Confident	54 Å²	54	94.1 Å²	94.1	33%	0.331	48%	0.483	S	S	.	.	H	α-helix	trans	-61.3	-45.9	175.2	-56.2	0	0	0	0	110.8	L159 L160 F161 T166 V167	L159-T163 WeakPolarHBondContact O-CB 3.41Å; L159-T163 PolarHBondContact O-N 2.88Å; L159-T163 PolarHBondContact O-OG1 3.15Å; L160-T163 PolarHBondContact O-N 3.38Å; F161-T163 VanDerWaalsContact C-N 3.33Å; F161-T163 PolarHBondContact O-N 2.97Å; T163-T166 PolarHBondContact O-N 2.84Å; T163-V167 HydrophobicContact CG2-CG2 4.23Å; T163-V167 WeakPolarHBondContact O-CB 3.41Å; T163-V167 VanDerWaalsContact O-CG2 3.24Å; T163-V167 WeakPolarHBondContact O-CG2 3.33Å; T163-V167 PolarHBondContact O-N 2.96Å
164	R	80.1	Confident	84.8	Confident	129 Å²	129	91.6 Å²	91.6	49%	0.487	47%	0.465	S	S	.	.	H	α-helix	trans	-61	-48.9	176.5	177.1	-177.8	173.8	-168.3	-2.7	111.9	V143 L160 F161 T166 L168	V143-R164 HydrophobicContact CG1-CG 4.46Å; L160-R164 WeakPolarHBondContact O-CB 3.39Å; L160-R164 PolarHBondContact O-N 3.13Å; F161-R164 PolarHBondContact O-N 3.39Å; R164-T166 VanDerWaalsContact C-N 3.34Å; R164-L168 WeakPolarHBondContact O-CB 3.35Å; R164-L168 PolarHBondContact O-N 3.05Å
165	F	83.4	Confident	85.6	Confident	119 Å²	119	87 Å²	87	52%	0.522	44%	0.441	S	S	.	.	H	α-helix	trans	-59.7	-49	179.5	-177	-97.7	0	0	0	109.8	F161 L162 L168 T169	F161-F165 PolarHBondContact O-N 3.41Å; L162-F165 PolarHBondContact O-N 3.25Å; F165-L168 PolarHBondContact O-N 3.18Å; F165-T169 HydrophobicContact CD1-CG2 4.2Å; F165-T169 HydrophobicContact CD2-CG2 3.92Å; F165-T169 HydrophobicContact CE1-CG2 3.96Å; F165-T169 HydrophobicContact CE2-CG2 3.68Å; F165-T169 HydrophobicContact CG-CG2 4.18Å; F165-T169 HydrophobicContact CZ-CG2 3.7Å; F165-T169 VanDerWaalsContact O-CB 3.24Å; F165-T169 WeakPolarHBondContact O-CB 3.5Å; F165-T169 VanDerWaalsContact O-CG2 3.25Å; F165-T169 WeakPolarHBondContact O-CG2 3.25Å; F165-T169 PolarHBondContact O-N 2.97Å; F165-T169 PolarHBondContact O-OG1 3.32Å
166	T	87.7	Confident	86.2	Confident	73 Å²	73	82.5 Å²	82.5	45%	0.448	43%	0.429	S	S	.	.	H	α-helix	trans	-61.4	-50.7	-179.7	-53.5	0	0	0	0	111.9	L162 T163 R164 L168 T169 A170	L162-T166 VanDerWaalsContact O-CB 3.29Å; L162-T166 WeakPolarHBondContact O-CB 3.23Å; L162-T166 PolarHBondContact O-N 3.15Å; L162-T166 PolarHBondContact O-OG1 3.28Å; T163-T166 PolarHBondContact O-N 2.84Å; R164-T166 VanDerWaalsContact C-N 3.34Å; T166-L168 PolarHBondContact O-N 3.05Å; T166-T169 PolarHBondContact O-OG1 3.42Å; T166-A170 WeakPolarHBondContact O-CB 3.31Å; T166-A170 PolarHBondContact O-N 3.26Å
167	V	88.2	Confident	86.8	Confident	35 Å²	35	83.4 Å²	83.4	21%	0.212	43%	0.432	C	S	.	.	H	α-helix	trans	-62.2	-47.2	-179.9	172.6	0	0	0	0	111	I139 T163 T171	I139-V167 HydrophobicContact CG2-CG1 4.05Å; T163-V167 HydrophobicContact CG2-CG2 4.23Å; T163-V167 WeakPolarHBondContact O-CB 3.41Å; T163-V167 VanDerWaalsContact O-CG2 3.24Å; T163-V167 WeakPolarHBondContact O-CG2 3.33Å; T163-V167 PolarHBondContact O-N 2.96Å; V167-T171 HydrophobicContact CG1-CG2 4.44Å; V167-T171 VanDerWaalsContact O-CB 3.28Å; V167-T171 WeakPolarHBondContact O-CB 3.25Å; V167-T171 WeakPolarHBondContact O-CG2 3.27Å; V167-T171 PolarHBondContact O-N 3.43Å; V167-T171 PolarHBondContact O-OG1 3.46Å
168	L	87.4	Confident	87.5	Confident	95 Å²	95	80 Å²	80	50%	0.497	41%	0.408	S	S	.	.	H	α-helix	trans	-71.1	-41.7	-176.2	-173.6	63.2	0	0	0	112.4	R164 F165 T166 T171 G172	R164-L168 WeakPolarHBondContact O-CB 3.35Å; R164-L168 PolarHBondContact O-N 3.05Å; F165-L168 PolarHBondContact O-N 3.18Å; T166-L168 PolarHBondContact O-N 3.05Å; L168-T171 PolarHBondContact O-OG1 3.27Å; L168-G172 PolarHBondContact O-N 2.88Å
169	T	88.1	Confident	87.9	Confident	63 Å²	63	77.3 Å²	77.3	39%	0.387	40%	0.395	S	S	.	.	H	α-helix	trans	-70.8	-42.4	177.7	56.3	0	0	0	0	111.9	F165 T166 G172 W173	F165-T169 HydrophobicContact CD1-CG2 4.2Å; F165-T169 HydrophobicContact CD2-CG2 3.92Å; F165-T169 HydrophobicContact CE1-CG2 3.96Å; F165-T169 HydrophobicContact CE2-CG2 3.68Å; F165-T169 HydrophobicContact CG-CG2 4.18Å; F165-T169 HydrophobicContact CZ-CG2 3.7Å; F165-T169 VanDerWaalsContact O-CB 3.24Å; F165-T169 WeakPolarHBondContact O-CB 3.5Å; F165-T169 VanDerWaalsContact O-CG2 3.25Å; F165-T169 WeakPolarHBondContact O-CG2 3.25Å; F165-T169 PolarHBondContact O-N 2.97Å; F165-T169 PolarHBondContact O-OG1 3.32Å; T166-T169 PolarHBondContact O-OG1 3.42Å; T169-G172 PolarHBondContact O-N 3.5Å; T169-W173 WeakPolarHBondContact O-CB 3.39Å; T169-W173 PolarHBondContact O-N 2.88Å
170	A	90.8	Very high	88.4	Confident	52 Å²	52	77.4 Å²	77.4	43%	0.43	40%	0.395	S	S	.	.	H	α-helix	trans	-64.5	-47.1	177.2	0	0	0	0	0	111.4	T166 S174	T166-A170 WeakPolarHBondContact O-CB 3.31Å; T166-A170 PolarHBondContact O-N 3.26Å; A170-S174 WeakPolarHBondContact O-CB 3.26Å; A170-S174 PolarHBondContact O-N 2.98Å
171	T	89.8	Confident	88.9	Confident	33 Å²	33	79 Å²	79	20%	0.202	40%	0.401	C	S	.	.	H	α-helix	trans	-65.9	-41.9	177.6	54.4	0	0	0	0	111.8	I139 V167 L168 L175	I139-T171 HydrophobicContact CD1-CG2 3.8Å; I139-T171 HydrophobicContact CG1-CG2 4.37Å; V167-T171 HydrophobicContact CG1-CG2 4.44Å; V167-T171 VanDerWaalsContact O-CB 3.28Å; V167-T171 WeakPolarHBondContact O-CB 3.25Å; V167-T171 WeakPolarHBondContact O-CG2 3.27Å; V167-T171 PolarHBondContact O-N 3.43Å; V167-T171 PolarHBondContact O-OG1 3.46Å; L168-T171 PolarHBondContact O-OG1 3.27Å; T171-L175 VanDerWaalsContact O-CB 3.25Å; T171-L175 WeakPolarHBondContact O-CB 3.35Å; T171-L175 PolarHBondContact O-N 3.34Å
172	G	90.8	Very high	89.4	Confident	35 Å²	35	72.4 Å²	72.4	36%	0.361	37%	0.372	S	S	.	.	H	α-helix	trans	-65.1	-44.5	176.7	0	0	0	0	0	113.3	L168 T169 L175 C176	L168-G172 PolarHBondContact O-N 2.88Å; T169-G172 PolarHBondContact O-N 3.5Å; G172-L175 PolarHBondContact O-N 2.9Å; G172-C176 WeakPolarHBondContact O-CB 3.21Å; G172-C176 PolarHBondContact O-N 3.41Å
173	W	92.9	Very high	89.7	Confident	189 Å²	189	73.2 Å²	73.2	72%	0.716	37%	0.371	S	S	*	.	H	α-helix	trans	-62.3	-47.9	175.6	175.9	-102.1	0	0	0	111.5	T169 L175 C176 R177	T169-W173 WeakPolarHBondContact O-CB 3.39Å; T169-W173 PolarHBondContact O-N 2.88Å; W173-L175 VanDerWaalsContact C-N 3.34Å; W173-L175 PolarHBondContact O-N 3.4Å; W173-C176 PolarHBondContact O-N 3.16Å; W173-R177 WeakPolarHBondContact O-CB 3.38Å; W173-R177 PolarHBondContact O-N 3.47Å
174	S	91.8	Very high	90.2	Very high	26 Å²	26	81.1 Å²	81.1	18%	0.182	40%	0.395	C	S	.	.	H	α-helix	trans	-58.1	-46.3	177	-173.3	0	0	0	0	111.6	M128 A170 S178	M128-S174 WeakPolarHBondContact CE-OG 3.48Å; M128-S174 WeakPolarHBondContact CG-OG 3.44Å; M128-S174 PolarHBondContact SD-OG 3.1Å; A170-S174 WeakPolarHBondContact O-CB 3.26Å; A170-S174 PolarHBondContact O-N 2.98Å; S174-S178 PolarHBondContact O-N 3.01Å; S174-S178 PolarHBondContact O-OG 3.33Å
175	L	91.8	Very high	90.6	Very high	54 Å²	54	78.5 Å²	78.5	28%	0.283	39%	0.393	S	S	.	.	H	α-helix	trans	-62.4	-48.3	177.1	-175	70.1	0	0	0	111.2	V129 I132 T171 G172 W173 R177 S178 L179	V129-L175 HydrophobicContact CG1-CD1 4.32Å; V129-L175 HydrophobicContact CG2-CD1 4.19Å; I132-L175 HydrophobicContact CB-CD1 4.46Å; I132-L175 HydrophobicContact CD1-CB 4.12Å; I132-L175 HydrophobicContact CD1-CD1 4.41Å; I132-L175 HydrophobicContact CG2-CD1 4.12Å; T171-L175 VanDerWaalsContact O-CB 3.25Å; T171-L175 WeakPolarHBondContact O-CB 3.35Å; T171-L175 PolarHBondContact O-N 3.34Å; G172-L175 PolarHBondContact O-N 2.9Å; W173-L175 VanDerWaalsContact C-N 3.34Å; W173-L175 PolarHBondContact O-N 3.4Å; L175-R177 PolarHBondContact O-N 3.43Å; L175-S178 PolarHBondContact O-N 3.39Å; L175-L179 HydrophobicContact CD1-CD1 4.31Å; L175-L179 HydrophobicContact CD1-CG 4.46Å; L175-L179 HydrophobicContact CG-CD1 3.92Å; L175-L179 HydrophobicContact CG-CG 4.42Å; L175-L179 WeakPolarHBondContact O-CB 3.36Å; L175-L179 VanDerWaalsContact O-CG 3.24Å; L175-L179 WeakPolarHBondContact O-CG 3.49Å; L175-L179 PolarHBondContact O-N 3.17Å
176	C	93.2	Very high	91	Very high	66 Å²	66	75.5 Å²	75.5	45%	0.446	38%	0.379	S	S	.	.	H	α-helix	trans	-60.7	-47.6	179.9	-171.3	0	0	0	0	111.6	G172 W173 S178 L179 I180	G172-C176 WeakPolarHBondContact O-CB 3.21Å; G172-C176 PolarHBondContact O-N 3.41Å; W173-C176 PolarHBondContact O-N 3.16Å; C176-S178 PolarHBondContact O-N 3.19Å; C176-L179 PolarHBondContact O-N 3.14Å; C176-I180 VanDerWaalsContact O-CG1 3.29Å; C176-I180 WeakPolarHBondContact O-CG1 3.31Å; C176-I180 PolarHBondContact O-N 3.47Å
177	R	93.7	Very high	91.2	Very high	164 Å²	164	75.3 Å²	75.3	62%	0.619	38%	0.381	S	S	*	.	H	α-helix	trans	-57	-48.5	176.8	178.4	-179	175.1	170.5	0.9	111.7	W173 L175 I180 H181	W173-R177 WeakPolarHBondContact O-CB 3.38Å; W173-R177 PolarHBondContact O-N 3.47Å; L175-R177 PolarHBondContact O-N 3.43Å; R177-I180 PolarHBondContact O-N 2.83Å; R177-H181 PolarHBondContact O-N 3.39Å; R177-H181 VanDerWaalsContact O-N 3.11Å
178	S	92.6	Very high	91.3	Very high	0 Å²	0	80.3 Å²	80.3	0%	0	40%	0.4	C	S	.	.	H	α-helix	trans	-65.9	-41.4	178.6	-72.6	0	0	0	0	112.6	N125 M128 S174 L175 C176 I180 H181 L182	N125-S178 PolarHBondContact OD1-OG 3.33Å; M128-S178 WeakPolarHBondContact CE-OG 3.16Å; S174-S178 PolarHBondContact O-N 3.01Å; S174-S178 PolarHBondContact O-OG 3.33Å; L175-S178 PolarHBondContact O-N 3.39Å; C176-S178 PolarHBondContact O-N 3.19Å; S178-I180 PolarHBondContact O-N 3.2Å; S178-H181 PolarHBondContact O-N 2.74Å; S178-L182 WeakPolarHBondContact O-CB 3.48Å; S178-L182 WeakPolarHBondContact O-CG 3.49Å; S178-L182 PolarHBondContact O-N 3.49Å
179	L	91.3	Very high	91.3	Very high	59 Å²	59	81.2 Å²	81.2	31%	0.309	41%	0.405	S	S	.	.	H	α-helix	trans	-61.7	-45.3	177.5	-73.2	174.4	0	0	0	111.1	V129 L175 C176 H181 L182 F183	V129-L179 HydrophobicContact CG2-CD2 4.29Å; V129-L179 HydrophobicContact CG2-CG 4.48Å; L175-L179 HydrophobicContact CD1-CD1 4.31Å; L175-L179 HydrophobicContact CD1-CG 4.46Å; L175-L179 HydrophobicContact CG-CD1 3.92Å; L175-L179 HydrophobicContact CG-CG 4.42Å; L175-L179 WeakPolarHBondContact O-CB 3.36Å; L175-L179 VanDerWaalsContact O-CG 3.24Å; L175-L179 WeakPolarHBondContact O-CG 3.49Å; L175-L179 PolarHBondContact O-N 3.17Å; C176-L179 PolarHBondContact O-N 3.14Å; L179-H181 VanDerWaalsContact C-N 3.29Å; L179-H181 PolarHBondContact O-N 2.93Å; L179-L182 HydrophobicContact CD2-CD1 4.49Å; L179-L182 PolarHBondContact O-N 2.71Å; L179-L182 VanDerWaalsContact O-N 3.15Å; L179-F183 HydrophobicContact CB-CD2 4.42Å; L179-F183 HydrophobicContact CB-CE2 4.41Å; L179-F183 WeakPolarHBondContact O-CD2 3.49Å; L179-F183 PolarHBondContact O-N 2.92Å
180	I	92.7	Very high	91.3	Very high	94 Å²	94	81.1 Å²	81.1	48%	0.482	40%	0.402	S	S	.	.	H	α-helix	trans	-57.5	-44.7	175.9	-68.2	165.1	0	0	0	110.6	C176 R177 S178 F183 R184	C176-I180 VanDerWaalsContact O-CG1 3.29Å; C176-I180 WeakPolarHBondContact O-CG1 3.31Å; C176-I180 PolarHBondContact O-N 3.47Å; R177-I180 PolarHBondContact O-N 2.83Å; S178-I180 PolarHBondContact O-N 3.2Å; I180-F183 PolarHBondContact O-N 2.72Å; I180-R184 WeakPolarHBondContact O-CG 3.21Å; I180-R184 PolarHBondContact O-N 3.42Å; I180-R184 VanDerWaalsContact O-N 3.14Å
181	H	92.3	Very high	91.2	Very high	83 Å²	83	79 Å²	79	38%	0.384	38%	0.383	S	S	.	.	H	α-helix	trans	-62.8	-44.2	176.5	-176	-78.1	0	0	0	112.1	N125 R177 S178 L179 R184 T185	N125-H181 HydrophobicContact CB-CB 4.45Å; N125-H181 PolarHBondContact ND2-CE1 3.3Å; N125-H181 VanDerWaalsContact ND2-CG 3.29Å; N125-H181 PolarHBondContact ND2-ND1 3.01Å; N125-H181 VanDerWaalsContact ND2-ND1 3.1Å; R177-H181 PolarHBondContact O-N 3.39Å; R177-H181 VanDerWaalsContact O-N 3.11Å; S178-H181 PolarHBondContact O-N 2.74Å; L179-H181 VanDerWaalsContact C-N 3.29Å; L179-H181 PolarHBondContact O-N 2.93Å; H181-R184 PolarHBondContact O-N 2.96Å; H181-R184 VanDerWaalsContact O-N 3.17Å; H181-T185 PolarHBondContact CE1-OG1 3.02Å; H181-T185 PolarHBondContact ND1-OG1 3.39Å; H181-T185 WeakPolarHBondContact O-CB 3.31Å; H181-T185 PolarHBondContact O-N 3.31Å; H181-T185 PolarHBondContact O-OG1 2.88Å
182	L	92	Very high	91.2	Very high	0 Å²	0	82 Å²	82	0%	0	40%	0.397	C	S	.	.	H	α-helix	trans	-63	-42.6	178.4	-72.6	170.6	0	0	0	111.9	N125 L126 V129 S178 L179 R184 T185 Y186 L191 L194	N125-L182 HydrophobicContact CB-CD2 4.49Å; N125-L182 HydrophobicContact CB-CG 4.35Å; L126-L182 HydrophobicContact CB-CD2 4.18Å; V129-L182 HydrophobicContact CB-CD1 4.33Å; V129-L182 HydrophobicContact CG2-CD1 3.67Å; S178-L182 WeakPolarHBondContact O-CB 3.48Å; S178-L182 WeakPolarHBondContact O-CG 3.49Å; S178-L182 PolarHBondContact O-N 3.49Å; L179-L182 HydrophobicContact CD2-CD1 4.49Å; L179-L182 PolarHBondContact O-N 2.71Å; L179-L182 VanDerWaalsContact O-N 3.15Å; L182-R184 PolarHBondContact O-N 2.95Å; L182-T185 PolarHBondContact O-N 3.05Å; L182-T185 VanDerWaalsContact O-N 3.09Å; L182-Y186 HydrophobicContact CD2-CD2 3.72Å; L182-Y186 HydrophobicContact CD2-CE2 3.55Å; L182-Y186 PolarHBondContact O-N 3.42Å; L182-L191 HydrophobicContact CB-CD2 3.79Å; L182-L194 HydrophobicContact CD1-CD1 4.21Å
183	F	91.7	Very high	91.1	Very high	114 Å²	114	83.5 Å²	83.5	50%	0.5	39%	0.394	S	S	.	.	H	α-helix	trans	-61.5	-29.5	173.6	-83	-67.6	0	0	0	113.4	L179 I180 F188 L191	L179-F183 HydrophobicContact CB-CD2 4.42Å; L179-F183 HydrophobicContact CB-CE2 4.41Å; L179-F183 WeakPolarHBondContact O-CD2 3.49Å; L179-F183 PolarHBondContact O-N 2.92Å; I180-F183 PolarHBondContact O-N 2.72Å; F183-F188 AromaticContact CE1-CD2 3.96Å; F183-F188 HydrophobicContact CE1-CD2 3.96Å; F183-F188 HydrophobicContact CE1-CE2 4.35Å; F183-L191 HydrophobicContact CB-CD1 4.21Å; F183-L191 HydrophobicContact CD1-CD1 3.27Å; F183-L191 HydrophobicContact CD2-CD1 4.43Å; F183-L191 HydrophobicContact CE1-CB 4.39Å; F183-L191 HydrophobicContact CE1-CD1 3.6Å; F183-L191 HydrophobicContact CG-CD1 3.73Å; F183-L191 HydrophobicContact CZ-CD1 4.3Å
184	R	91.7	Very high	90.9	Very high	220 Å²	220	75 Å²	75	83%	0.83	36%	0.363	S	S	*	.	H	α-helix	trans	-81.1	-24.6	174.4	-69.7	179	67.8	170.1	2.3	113.2	I180 H181 L182	I180-R184 WeakPolarHBondContact O-CG 3.21Å; I180-R184 PolarHBondContact O-N 3.42Å; I180-R184 VanDerWaalsContact O-N 3.14Å; H181-R184 PolarHBondContact O-N 2.96Å; H181-R184 VanDerWaalsContact O-N 3.17Å; L182-R184 PolarHBondContact O-N 2.95Å
185	T	89.9	Confident	90.6	Very high	74 Å²	74	77.1 Å²	77.1	45%	0.454	38%	0.377	S	S	.	.	H	α-helix	trans	-97	-38.4	-172.4	-52.5	0	0	0	0	112.4	H181 L182	H181-T185 PolarHBondContact CE1-OG1 3.02Å; H181-T185 PolarHBondContact ND1-OG1 3.39Å; H181-T185 WeakPolarHBondContact O-CB 3.31Å; H181-T185 PolarHBondContact O-N 3.31Å; H181-T185 PolarHBondContact O-OG1 2.88Å; L182-T185 PolarHBondContact O-N 3.05Å; L182-T185 VanDerWaalsContact O-N 3.09Å
186	Y	91.2	Very high	90.1	Very high	57 Å²	57	80.8 Å²	80.8	22%	0.224	39%	0.388	C	S	.	.	S	Bend	trans	-118.8	152.7	-174.6	-58.2	-78.8	0	0	0	111.9	D123 L182 F307	D123-Y186 VanDerWaalsContact OD2-CE2 3.23Å; D123-Y186 WeakPolarHBondContact OD2-CE2 3.5Å; D123-Y186 PolarHBondContact OD2-OH 3.3Å; L182-Y186 HydrophobicContact CD2-CD2 3.72Å; L182-Y186 HydrophobicContact CD2-CE2 3.55Å; L182-Y186 PolarHBondContact O-N 3.42Å; Y186-F307 AromaticContact CD1-CD1 3.87Å; Y186-F307 HydrophobicContact CD1-CD1 3.87Å; Y186-F307 HydrophobicContact CD1-CE1 4.16Å; Y186-F307 HydrophobicContact CD2-CD1 4.02Å; Y186-F307 AromaticContact CD2-CE1 3.94Å; Y186-F307 HydrophobicContact CD2-CE1 3.94Å; Y186-F307 AromaticContact CE1-CD1 3.78Å; Y186-F307 HydrophobicContact CE1-CD1 3.78Å; Y186-F307 HydrophobicContact CE1-CE1 4.49Å; Y186-F307 AromaticContact CE2-CD1 3.95Å; Y186-F307 HydrophobicContact CE2-CD1 3.95Å; Y186-F307 HydrophobicContact CE2-CE1 4.3Å; Y186-F307 AromaticContact CG-CD1 3.99Å; Y186-F307 HydrophobicContact CG-CD1 3.99Å; Y186-F307 AromaticContact CG-CE1 3.87Å; Y186-F307 HydrophobicContact CG-CE1 3.87Å; Y186-F307 AromaticContact CZ-CD1 3.84Å
187	S	91.6	Very high	89.5	Confident	69 Å²	69	78.2 Å²	78.2	48%	0.483	37%	0.37	S	S	.	.			trans	-58.9	146.4	171.9	171.6	0	0	0	0	111.7	L189 N190 L191	S187-L189 PolarHBondContact O-N 2.88Å; S187-L189 PolarHBondContact OG-N 2.84Å; S187-N190 WeakPolarHBondContact O-CB 3.29Å; S187-N190 PolarHBondContact O-N 3.11Å; S187-L191 PolarHBondContact O-N 3.27Å
188	F	89.5	Confident	88.7	Confident	140 Å²	140	73.9 Å²	73.9	61%	0.614	36%	0.356	S	S	*	.	H	α-helix	trans	-51.2	-39.4	174.4	-179.2	-97.6	0	0	0	112.9	F183 N190 L191 L192	F183-F188 AromaticContact CE1-CD2 3.96Å; F183-F188 HydrophobicContact CE1-CD2 3.96Å; F183-F188 HydrophobicContact CE1-CE2 4.35Å; F188-N190 VanDerWaalsContact C-N 3.33Å; F188-N190 PolarHBondContact O-N 2.92Å; F188-L191 PolarHBondContact O-N 3.24Å; F188-L192 PolarHBondContact O-N 3.5Å
189	L	87.5	Confident	87.7	Confident	113 Å²	113	75.9 Å²	75.9	59%	0.592	38%	0.377	S	S	*	.	H	α-helix	trans	-62.8	-39.3	178.5	-68.8	178.1	0	0	0	112.2	S187 L191 L192 F193	S187-L189 PolarHBondContact O-N 2.88Å; S187-L189 PolarHBondContact OG-N 2.84Å; L189-L191 VanDerWaalsContact C-N 3.3Å; L189-L191 PolarHBondContact O-N 3.15Å; L189-L192 WeakPolarHBondContact O-CB 3.46Å; L189-L192 PolarHBondContact O-N 3.36Å; L189-F193 VanDerWaalsContact O-CD2 3.24Å; L189-F193 WeakPolarHBondContact O-CD2 3.42Å
190	N	88	Confident	86.6	Confident	61 Å²	61	78.3 Å²	78.3	33%	0.326	39%	0.388	S	S	.	.	H	α-helix	trans	-67.7	-36.2	177.3	-70	-5.6	0	0	0	111.1	S187 F188 L192 F193 F307	S187-N190 WeakPolarHBondContact O-CB 3.29Å; S187-N190 PolarHBondContact O-N 3.11Å; F188-N190 VanDerWaalsContact C-N 3.33Å; F188-N190 PolarHBondContact O-N 2.92Å; N190-L192 VanDerWaalsContact C-N 3.3Å; N190-L192 PolarHBondContact O-N 3.48Å; N190-F193 WeakPolarHBondContact O-CB 3.23Å; N190-F193 PolarHBondContact O-N 3.26Å; N190-F307 HydrophobicContact CB-CE1 4.32Å; N190-F307 WeakPolarHBondContact O-CZ 3.25Å
191	L	90.3	Very high	85.5	Confident	9 Å²	9	75 Å²	75	5%	0.047	37%	0.369	C	S	.	.	H	α-helix	trans	-72.3	-25.1	177.5	-60.7	172.4	0	0	0	112.4	L182 F183 S187 F188 L189 F193 L194 F307	L182-L191 HydrophobicContact CB-CD2 3.79Å; F183-L191 HydrophobicContact CB-CD1 4.21Å; F183-L191 HydrophobicContact CD1-CD1 3.27Å; F183-L191 HydrophobicContact CD2-CD1 4.43Å; F183-L191 HydrophobicContact CE1-CB 4.39Å; F183-L191 HydrophobicContact CE1-CD1 3.6Å; F183-L191 HydrophobicContact CG-CD1 3.73Å; F183-L191 HydrophobicContact CZ-CD1 4.3Å; S187-L191 PolarHBondContact O-N 3.27Å; F188-L191 PolarHBondContact O-N 3.24Å; L189-L191 VanDerWaalsContact C-N 3.3Å; L189-L191 PolarHBondContact O-N 3.15Å; L191-F193 PolarHBondContact O-N 2.89Å; L191-L194 HydrophobicContact CD2-CD1 3.82Å; L191-L194 WeakPolarHBondContact O-CB 2.83Å; L191-L194 PolarHBondContact O-N 3.35Å; L191-L194 VanDerWaalsContact O-N 3.07Å; L191-F307 HydrophobicContact CD2-CE1 4.14Å; L191-F307 HydrophobicContact CD2-CZ 4.23Å
192	L	88.2	Confident	84.3	Confident	94 Å²	94	75 Å²	75	49%	0.492	37%	0.372	S	S	.	.	H	α-helix	trans	-61.6	-30.9	173.4	-171.6	62.6	0	0	0	112	F188 L189 N190 L194 C195 Y196	F188-L192 PolarHBondContact O-N 3.5Å; L189-L192 WeakPolarHBondContact O-CB 3.46Å; L189-L192 PolarHBondContact O-N 3.36Å; N190-L192 VanDerWaalsContact C-N 3.3Å; N190-L192 PolarHBondContact O-N 3.48Å; L192-L194 VanDerWaalsContact C-N 3.31Å; L192-L194 PolarHBondContact O-N 3.13Å; L192-C195 CarbonylContact O-C 3.55Å; L192-C195 WeakPolarHBondContact O-CA 3.16Å; L192-C195 PolarHBondContact O-N 2.97Å; L192-Y196 PolarHBondContact O-N 3.41Å
193	F	88.3	Confident	83.1	Confident	68 Å²	68	78.3 Å²	78.3	30%	0.298	39%	0.393	S	S	.	.	H	α-helix	trans	-62.6	-37.3	173.9	-72.8	-85.9	0	0	0	111.8	L189 N190 L191 C195 Y196 Y298 F302 W306	L189-F193 VanDerWaalsContact O-CD2 3.24Å; L189-F193 WeakPolarHBondContact O-CD2 3.42Å; N190-F193 WeakPolarHBondContact O-CB 3.23Å; N190-F193 PolarHBondContact O-N 3.26Å; L191-F193 PolarHBondContact O-N 2.89Å; F193-C195 PolarHBondContact O-N 3.42Å; F193-C195 VanDerWaalsContact O-N 3.1Å; F193-Y196 WeakPolarHBondContact O-CB 3.43Å; F193-Y196 PolarHBondContact O-N 3.28Å; F193-Y196 VanDerWaalsContact O-N 3.09Å; F193-Y298 WeakPolarHBondContact O-CE1 3.48Å; F193-Y298 PolarHBondContact O-OH 3.48Å; F193-F302 HydrophobicContact CD1-CE1 4.37Å; F193-W306 HydrophobicContact CD1-CH2 4.35Å; F193-W306 HydrophobicContact CD1-CZ2 4.09Å; F193-W306 AromaticContact CD2-CE2 3.61Å; F193-W306 HydrophobicContact CD2-CH2 4.42Å; F193-W306 AromaticContact CD2-CZ2 3.49Å; F193-W306 HydrophobicContact CD2-CZ2 3.49Å; F193-W306 VanDerWaalsContact CD2-CZ2 3.49Å; F193-W306 AromaticContact CD2-NE1 3.57Å; F193-W306 AromaticContact CE1-CH2 3.79Å; F193-W306 HydrophobicContact CE1-CH2 3.79Å; F193-W306 AromaticContact CE1-CZ2 3.82Å; F193-W306 HydrophobicContact CE1-CZ2 3.82Å; F193-W306 HydrophobicContact CE1-CZ3 4.35Å; F193-W306 AromaticContact CE2-CE2 3.84Å; F193-W306 AromaticContact CE2-CH2 3.89Å; F193-W306 HydrophobicContact CE2-CH2 3.89Å; F193-W306 AromaticContact CE2-CZ2 3.2Å; F193-W306 HydrophobicContact CE2-CZ2 3.2Å; F193-W306 HydrophobicContact CG-CD2 4.42Å; F193-W306 AromaticContact CG-CE2 3.79Å; F193-W306 AromaticContact CG-CZ2 3.94Å; F193-W306 HydrophobicContact CG-CZ2 3.94Å; F193-W306 AromaticContact CG-NE1 3.83Å; F193-W306 AromaticContact CZ-CH2 3.54Å; F193-W306 HydrophobicContact CZ-CH2 3.54Å; F193-W306 AromaticContact CZ-CZ2 3.37Å; F193-W306 HydrophobicContact CZ-CZ2 3.37Å
194	L	88.9	Confident	81.7	Confident	10 Å²	10	75.8 Å²	75.8	5%	0.052	38%	0.382	C	S	.	.	H	α-helix	trans	-59.6	-25.7	172.8	-67.2	169.4	0	0	0	112.6	L126 L182 L191 L192 Y299 V303 F307	L126-L194 HydrophobicContact CD1-CD1 4.32Å; L126-L194 HydrophobicContact CD1-CD2 3.89Å; L182-L194 HydrophobicContact CD1-CD1 4.21Å; L191-L194 HydrophobicContact CD2-CD1 3.82Å; L191-L194 WeakPolarHBondContact O-CB 2.83Å; L191-L194 PolarHBondContact O-N 3.35Å; L191-L194 VanDerWaalsContact O-N 3.07Å; L192-L194 VanDerWaalsContact C-N 3.31Å; L192-L194 PolarHBondContact O-N 3.13Å; L194-Y299 HydrophobicContact CD2-CE1 4.43Å; L194-Y299 PolarHBondContact O-OH 2.79Å; L194-V303 HydrophobicContact CD2-CG1 3.54Å; L194-V303 HydrophobicContact CD2-CG2 4.22Å; L194-F307 HydrophobicContact CD1-CE2 4.14Å; L194-F307 HydrophobicContact CD1-CZ 3.74Å; L194-F307 HydrophobicContact CD2-CE2 3.71Å; L194-F307 HydrophobicContact CD2-CZ 4.19Å; L194-F307 HydrophobicContact CG-CE2 3.71Å; L194-F307 HydrophobicContact CG-CZ 3.7Å
195	C	85.3	Confident	80.1	Confident	71 Å²	71	66.4 Å²	66.4	48%	0.48	35%	0.348	S	S	.	.	H	α-helix	trans	-99.2	-9.1	179.3	-65.2	0	0	0	0	113.6	L192 F193 F198 G199	L192-C195 CarbonylContact O-C 3.55Å; L192-C195 WeakPolarHBondContact O-CA 3.16Å; L192-C195 PolarHBondContact O-N 2.97Å; F193-C195 PolarHBondContact O-N 3.42Å; F193-C195 VanDerWaalsContact O-N 3.1Å; C195-F198 WeakPolarHBondContact O-CB 3.37Å; C195-F198 PolarHBondContact O-N 2.9Å; C195-G199 PolarHBondContact O-N 3.42Å
196	Y	83.1	Confident	78.6	Confident	130 Å²	130	67.1 Å²	67.1	51%	0.51	35%	0.346	S	S	.	.	H	α-helix	trans	-56.7	-45.1	-172.3	179.6	-96	0	0	0	113.6	L192 F193 F198 G199 M200	L192-Y196 PolarHBondContact O-N 3.41Å; F193-Y196 WeakPolarHBondContact O-CB 3.43Å; F193-Y196 PolarHBondContact O-N 3.28Å; F193-Y196 VanDerWaalsContact O-N 3.09Å; Y196-F198 VanDerWaalsContact C-N 3.32Å; Y196-F198 PolarHBondContact O-N 2.92Å; Y196-G199 PolarHBondContact O-N 2.98Å; Y196-G199 VanDerWaalsContact O-N 3.17Å; Y196-M200 HydrophobicContact CD1-CG 4.43Å; Y196-M200 HydrophobicContact CE1-CG 3.97Å; Y196-M200 PolarHBondContact O-N 2.9Å; Y196-M200 VanDerWaalsContact O-N 3.12Å
197	P	80.8	Confident	76.9	Confident	12 Å²	12	69.5 Å²	69.5	8%	0.078	36%	0.362	C	S	.	.	H	α-helix	trans	-59	-43.3	175.2	-23.2	33.7	0	0	0	112.1	G199 M200 Y201 L295 Y298 Y299	P197-G199 VanDerWaalsContact C-N 3.28Å; P197-G199 PolarHBondContact O-N 2.88Å; P197-M200 CarbonylContact O-C 3.55Å; P197-M200 WeakPolarHBondContact O-CA 3.34Å; P197-M200 PolarHBondContact O-N 3.46Å; P197-Y201 WeakPolarHBondContact O-CD2 3.36Å; P197-Y201 PolarHBondContact O-N 3.09Å; P197-L295 HydrophobicContact CB-CD1 3.19Å; P197-L295 HydrophobicContact CG-CD1 3.91Å; P197-Y298 HydrophobicContact CG-CD1 3.25Å; P197-Y298 HydrophobicContact CG-CD2 4.21Å; P197-Y298 HydrophobicContact CG-CE1 3.4Å; P197-Y298 VanDerWaalsContact CG-CE1 3.4Å; P197-Y298 HydrophobicContact CG-CE2 4.33Å; P197-Y298 HydrophobicContact CG-CG 3.69Å; P197-Y299 HydrophobicContact CG-CE2 4.33Å
198	F	76.2	Confident	75.2	Confident	74 Å²	74	66.9 Å²	66.9	33%	0.325	34%	0.343	S	S	.	.	H	α-helix	trans	-62.4	-36.3	178.6	-63.1	-68.3	0	0	0	112.5	V133 C195 Y196 M200 Y201 I202 Y299	V133-F198 HydrophobicContact CG1-CE2 4.22Å; V133-F198 HydrophobicContact CG1-CZ 3.76Å; C195-F198 WeakPolarHBondContact O-CB 3.37Å; C195-F198 PolarHBondContact O-N 2.9Å; Y196-F198 VanDerWaalsContact C-N 3.32Å; Y196-F198 PolarHBondContact O-N 2.92Å; F198-M200 VanDerWaalsContact C-N 3.31Å; F198-M200 PolarHBondContact O-N 3.32Å; F198-Y201 WeakPolarHBondContact O-CB 3.39Å; F198-Y201 PolarHBondContact O-N 3.38Å; F198-I202 WeakPolarHBondContact O-CG1 3.28Å; F198-I202 PolarHBondContact O-N 3.42Å; F198-Y299 HydrophobicContact CE2-CE2 4.49Å; F198-Y299 WeakPolarHBondContact CE2-OH 3.2Å
199	G	71.4	Confident	73.4	Confident	42 Å²	42	61.2 Å²	61.2	43%	0.433	32%	0.32	S	S	.	.	H	α-helix	trans	-59	-41.2	171.5	0	0	0	0	0	112.5	C195 Y196 P197 P203	C195-G199 PolarHBondContact O-N 3.42Å; Y196-G199 PolarHBondContact O-N 2.98Å; Y196-G199 VanDerWaalsContact O-N 3.17Å; P197-G199 VanDerWaalsContact C-N 3.28Å; P197-G199 PolarHBondContact O-N 2.88Å; G199-P203 WeakPolarHBondContact O-CD 3.31Å
200	M	68.8	Low	71.8	Confident	110 Å²	110	60.2 Å²	60.2	54%	0.542	32%	0.316	S	S	.	.	H	α-helix	trans	-75	-27.1	176.1	-63	-56.6	-66.2	0	0	113.6	Y196 P197 F198	Y196-M200 HydrophobicContact CD1-CG 4.43Å; Y196-M200 HydrophobicContact CE1-CG 3.97Å; Y196-M200 PolarHBondContact O-N 2.9Å; Y196-M200 VanDerWaalsContact O-N 3.12Å; P197-M200 CarbonylContact O-C 3.55Å; P197-M200 WeakPolarHBondContact O-CA 3.34Å; P197-M200 PolarHBondContact O-N 3.46Å; F198-M200 VanDerWaalsContact C-N 3.31Å; F198-M200 PolarHBondContact O-N 3.32Å
201	Y	69	Low	70.1	Confident	24 Å²	24	61.3 Å²	61.3	9%	0.094	32%	0.321	C	S	.	.	H	α-helix	trans	-65.5	-37.1	175.9	-97.1	-107.6	0	0	0	112.3	R136 P197 F198 F204 L205 V291 S292 L295	R136-Y201 PolarHBondContact NH2-OH 3.5Å; P197-Y201 WeakPolarHBondContact O-CD2 3.36Å; P197-Y201 PolarHBondContact O-N 3.09Å; F198-Y201 WeakPolarHBondContact O-CB 3.39Å; F198-Y201 PolarHBondContact O-N 3.38Å; Y201-F204 PolarHBondContact O-N 2.97Å; Y201-L205 HydrophobicContact CD1-CD1 4.05Å; Y201-L205 WeakPolarHBondContact O-CD1 3.46Å; Y201-L205 PolarHBondContact O-N 3.35Å; Y201-V291 HydrophobicContact CD1-CG1 3.63Å; Y201-V291 HydrophobicContact CD2-CG1 3.73Å; Y201-V291 HydrophobicContact CE1-CG1 3.16Å; Y201-V291 HydrophobicContact CE2-CG1 3.29Å; Y201-V291 HydrophobicContact CG-CG1 3.93Å; Y201-V291 VanDerWaalsContact OH-C 3.25Å; Y201-V291 WeakPolarHBondContact OH-CG1 3.45Å; Y201-V291 PolarHBondContact OH-O 3.12Å; Y201-V291 VanDerWaalsContact OH-O 3.07Å; Y201-S292 VanDerWaalsContact OH-CA 3.29Å; Y201-S292 WeakPolarHBondContact OH-CA 3.38Å; Y201-S292 PolarHBondContact OH-N 3.33Å; Y201-L295 HydrophobicContact CE2-CB 3.96Å; Y201-L295 HydrophobicContact CE2-CD1 3.75Å; Y201-L295 HydrophobicContact CE2-CD2 4.08Å; Y201-L295 HydrophobicContact CE2-CG 4.14Å; Y201-L295 WeakPolarHBondContact OH-CB 3.48Å; Y201-L295 WeakPolarHBondContact OH-CD2 3.33Å
202	I	67.1	Low	68.3	Low	84 Å²	84	64 Å²	64	43%	0.431	33%	0.33	S	S	.	.	H	α-helix	trans	-63.9	-51.9	-173.3	-67.7	164.6	0	0	0	112.3	F198 F204 L205 Q206	F198-I202 WeakPolarHBondContact O-CG1 3.28Å; F198-I202 PolarHBondContact O-N 3.42Å; I202-F204 VanDerWaalsContact C-N 3.26Å; I202-F204 PolarHBondContact O-N 3.47Å; I202-L205 PolarHBondContact O-N 2.92Å; I202-Q206 HydrophobicContact CG2-CG 4.36Å; I202-Q206 WeakPolarHBondContact O-CB 3.24Å; I202-Q206 WeakPolarHBondContact O-CG 3.48Å; I202-Q206 PolarHBondContact O-N 2.8Å
203	P	66.1	Low	66.6	Low	69 Å²	69	65 Å²	65	45%	0.448	33%	0.331	S	S	.	.	H	α-helix	trans	-60.4	-37.6	176.1	-24.1	33	0	0	0	112.4	G199 Q206 L207	G199-P203 WeakPolarHBondContact O-CD 3.31Å; P203-Q206 PolarHBondContact O-N 3.1Å; P203-L207 WeakPolarHBondContact O-CB 3.43Å; P203-L207 PolarHBondContact O-N 2.92Å
204	F	62.4	Low	64.8	Low	60 Å²	60	65.5 Å²	65.5	26%	0.263	34%	0.34	S	S	.	.	H	α-helix	trans	-65.8	-42.3	178.6	-167.6	-98.4	0	0	0	111.5	Y201 I202 N208 K287 V291	Y201-F204 PolarHBondContact O-N 2.97Å; I202-F204 VanDerWaalsContact C-N 3.26Å; I202-F204 PolarHBondContact O-N 3.47Å; F204-N208 PolarHBondContact O-N 2.93Å; F204-N208 PolarHBondContact O-ND2 3.5Å; F204-K287 HydrophobicContact CE1-CB 3.55Å; F204-K287 HydrophobicContact CE1-CD 4.09Å; F204-K287 HydrophobicContact CE1-CG 4.03Å; F204-K287 HydrophobicContact CE2-CD 4.28Å; F204-K287 HydrophobicContact CE2-CG 4.23Å; F204-K287 HydrophobicContact CZ-CB 3.37Å; F204-K287 HydrophobicContact CZ-CD 3.66Å; F204-K287 HydrophobicContact CZ-CG 3.39Å; F204-V291 HydrophobicContact CD1-CG2 3.91Å; F204-V291 HydrophobicContact CE1-CB 4.4Å; F204-V291 HydrophobicContact CE1-CG2 3.51Å; F204-V291 HydrophobicContact CE2-CG2 4.26Å; F204-V291 HydrophobicContact CG-CG2 4.37Å; F204-V291 HydrophobicContact CZ-CG2 3.66Å
205	L	57.6	Low	63	Low	24 Å²	24	66.6 Å²	66.6	13%	0.126	35%	0.348	C	S	.	.	H	α-helix	trans	-66	-41.1	172.4	-95	76.9	0	0	0	112.3	Y201 I202 N208 C209 T245	Y201-L205 HydrophobicContact CD1-CD1 4.05Å; Y201-L205 WeakPolarHBondContact O-CD1 3.46Å; Y201-L205 PolarHBondContact O-N 3.35Å; I202-L205 PolarHBondContact O-N 2.92Å; L205-N208 PolarHBondContact O-N 3.4Å; L205-C209 PolarHBondContact O-N 3.39Å; L205-T245 HydrophobicContact CD2-CG2 4.09Å
206	Q	60.1	Low	61.2	Low	88 Å²	88	67.3 Å²	67.3	41%	0.411	35%	0.347	S	S	.	.	H	α-helix	trans	-60.3	-49.1	177.4	-76.4	173.7	-19.1	0	0	111.5	I202 P203 N208 C209 D210	I202-Q206 HydrophobicContact CG2-CG 4.36Å; I202-Q206 WeakPolarHBondContact O-CB 3.24Å; I202-Q206 WeakPolarHBondContact O-CG 3.48Å; I202-Q206 PolarHBondContact O-N 2.8Å; P203-Q206 PolarHBondContact O-N 3.1Å; Q206-N208 PolarHBondContact O-N 3.36Å; Q206-N208 VanDerWaalsContact O-N 3.13Å; Q206-C209 PolarHBondContact O-N 3.05Å; Q206-C209 VanDerWaalsContact O-N 3.13Å; Q206-D210 PolarHBondContact O-N 3.43Å
207	L	55.1	Low	59.5	Low	108 Å²	108	67.8 Å²	67.8	57%	0.565	35%	0.352	S	S	*	.	H	α-helix	trans	-58.1	-31.2	178	-155.5	108.8	0	0	0	112	P203 L211	P203-L207 WeakPolarHBondContact O-CB 3.43Å; P203-L207 PolarHBondContact O-N 2.92Å; L207-L211 PolarHBondContact O-N 3.24Å
208	N	54.9	Low	57.6	Low	13 Å²	13	73 Å²	73	7%	0.07	38%	0.379	C	S	.	.	H	α-helix	trans	-83.3	-37	178	-67.5	-39.1	0	0	0	113.2	F204 L205 Q206 D210 L211 R212 W284 K287	F204-N208 PolarHBondContact O-N 2.93Å; F204-N208 PolarHBondContact O-ND2 3.5Å; L205-N208 PolarHBondContact O-N 3.4Å; Q206-N208 PolarHBondContact O-N 3.36Å; Q206-N208 VanDerWaalsContact O-N 3.13Å; N208-D210 VanDerWaalsContact C-N 3.29Å; N208-L211 PolarHBondContact O-N 3.47Å; N208-R212 WeakPolarHBondContact O-CB 3.29Å; N208-R212 PolarHBondContact O-N 3.37Å; N208-W284 HydrophobicContact CB-CE3 3.65Å; N208-W284 HydrophobicContact CB-CH2 4.45Å; N208-W284 HydrophobicContact CB-CZ3 3.28Å; N208-W284 VanDerWaalsContact ND2-CZ3 3.26Å; N208-W284 WeakPolarHBondContact ND2-CZ3 3.49Å; N208-K287 PolarHBondContact OD1-NZ 3.17Å
209	C	52.7	Low	55.7	Low	21 Å²	21	76.1 Å²	76.1	14%	0.142	39%	0.394	C	S	.	.	H	α-helix	trans	-62.5	-39.7	170.4	-81.6	0	0	0	0	110.9	L205 Q206 K213 T245	L205-C209 PolarHBondContact O-N 3.39Å; Q206-C209 PolarHBondContact O-N 3.05Å; Q206-C209 VanDerWaalsContact O-N 3.13Å; C209-K213 VanDerWaalsContact O-CB 3.22Å; C209-K213 WeakPolarHBondContact O-CB 3.42Å; C209-K213 WeakPolarHBondContact O-CG 3.34Å; C209-K213 PolarHBondContact O-N 3.36Å; C209-T245 WeakPolarHBondContact SG-CG2 3.34Å
210	D	53.3	Low	53.7	Low	93 Å²	93	79.9 Å²	79.9	50%	0.497	40%	0.402	S	S	.	.	H	α-helix	trans	-66.9	-45.8	174.3	-74.4	-22.5	0	0	0	110.7	Q206 N208 R212 K213 T214	Q206-D210 PolarHBondContact O-N 3.43Å; N208-D210 VanDerWaalsContact C-N 3.29Å; D210-R212 VanDerWaalsContact C-N 3.31Å; D210-R212 PolarHBondContact O-N 2.9Å; D210-K213 CarbonylContact O-C 3.48Å; D210-K213 PolarHBondContact O-N 2.87Å; D210-T214 WeakPolarHBondContact O-CB 3.35Å; D210-T214 PolarHBondContact O-N 3.5Å; D210-T214 PolarHBondContact O-OG1 2.78Å
211	L	53	Low	52	Low	84 Å²	84	77.9 Å²	77.9	44%	0.44	40%	0.403	S	S	.	.	H	α-helix	trans	-57.8	-42.2	175.9	-125.6	82.5	0	0	0	112.9	L207 N208 T214 S215 M280	L207-L211 PolarHBondContact O-N 3.24Å; N208-L211 PolarHBondContact O-N 3.47Å; L211-T214 PolarHBondContact O-N 3.01Å; L211-S215 PolarHBondContact O-N 3.41Å; L211-M280 HydrophobicContact CB-SD 4.48Å; L211-M280 HydrophobicContact CD2-SD 3.81Å; L211-M280 HydrophobicContact CG-SD 4.47Å
212	R	52	Low	50.6	Low	64 Å²	64	81.2 Å²	81.2	24%	0.242	43%	0.43	C	S	.	.	H	α-helix	trans	-73.8	-37.1	177.8	-174.2	-176.7	-66.5	-118.6	-12	111.9	N208 D210 S215 L216	N208-R212 WeakPolarHBondContact O-CB 3.29Å; N208-R212 PolarHBondContact O-N 3.37Å; D210-R212 VanDerWaalsContact C-N 3.31Å; D210-R212 PolarHBondContact O-N 2.9Å; R212-S215 WeakPolarHBondContact CA-OG 3.48Å; R212-S215 PolarHBondContact O-N 3.3Å; R212-S215 PolarHBondContact O-OG 3.46Å; R212-L216 HydrophobicContact CG-CD1 3.99Å; R212-L216 HydrophobicContact CG-CG 4.28Å; R212-L216 VanDerWaalsContact O-CB 3.3Å; R212-L216 WeakPolarHBondContact O-CB 3.08Å; R212-L216 VanDerWaalsContact O-CG 3.28Å; R212-L216 WeakPolarHBondContact O-CG 3.29Å; R212-L216 PolarHBondContact O-N 2.91Å
213	K	53.4	Low	48.8	Very low	115 Å²	115	84.8 Å²	84.8	50%	0.5	45%	0.447	S	S	.	.	H	α-helix	trans	-62.8	-45.4	171.2	-84.3	-179.5	-178.7	178.1	0	109.2	C209 D210 S215 L216 F217	C209-K213 VanDerWaalsContact O-CB 3.22Å; C209-K213 WeakPolarHBondContact O-CB 3.42Å; C209-K213 WeakPolarHBondContact O-CG 3.34Å; C209-K213 PolarHBondContact O-N 3.36Å; D210-K213 CarbonylContact O-C 3.48Å; D210-K213 PolarHBondContact O-N 2.87Å; K213-S215 VanDerWaalsContact C-N 3.31Å; K213-S215 PolarHBondContact O-N 3.43Å; K213-L216 CarbonylContact O-C 3.51Å; K213-L216 PolarHBondContact O-N 3.49Å; K213-F217 WeakPolarHBondContact O-CA 3.36Å; K213-F217 WeakPolarHBondContact O-CB 3.33Å; K213-F217 PolarHBondContact O-N 2.9Å
214	T	50.1	Low	46.9	Very low	80 Å²	80	84.8 Å²	84.8	49%	0.491	46%	0.46	S	S	.	.	H	α-helix	trans	-59.3	-40.3	174.8	-53	0	0	0	0	111.4	D210 L211 N218	D210-T214 WeakPolarHBondContact O-CB 3.35Å; D210-T214 PolarHBondContact O-N 3.5Å; D210-T214 PolarHBondContact O-OG1 2.78Å; L211-T214 PolarHBondContact O-N 3.01Å; T214-N218 WeakPolarHBondContact O-CB 3.3Å; T214-N218 PolarHBondContact O-N 3.22Å; T214-N218 PolarHBondContact O-ND2 2.92Å; T214-N218 PolarHBondContact O-OD1 2.85Å
215	S	50.3	Low	45.6	Very low	33 Å²	33	88 Å²	88	23%	0.231	49%	0.486	C	S	.	.	H	α-helix	trans	-69.7	-41.9	175.7	70.9	0	0	0	0	113.1	L211 R212 K213 N218 H219	L211-S215 PolarHBondContact O-N 3.41Å; R212-S215 WeakPolarHBondContact CA-OG 3.48Å; R212-S215 PolarHBondContact O-N 3.3Å; R212-S215 PolarHBondContact O-OG 3.46Å; K213-S215 VanDerWaalsContact C-N 3.31Å; K213-S215 PolarHBondContact O-N 3.43Å; S215-N218 PolarHBondContact O-N 3.01Å; S215-H219 PolarHBondContact O-CD2 3.32Å; S215-H219 VanDerWaalsContact O-CD2 3.31Å; S215-H219 PolarHBondContact O-N 2.9Å; S215-H219 VanDerWaalsContact O-N 3.12Å
216	L	48.5	Very low	44.3	Very low	85 Å²	85	98.9 Å²	98.9	45%	0.445	53%	0.526	S	S	.	.	H	α-helix	trans	-70.6	-34.5	176.7	-72.2	174	0	0	0	111.7	R212 K213 H219 M220	R212-L216 HydrophobicContact CG-CD1 3.99Å; R212-L216 HydrophobicContact CG-CG 4.28Å; R212-L216 VanDerWaalsContact O-CB 3.3Å; R212-L216 WeakPolarHBondContact O-CB 3.08Å; R212-L216 VanDerWaalsContact O-CG 3.28Å; R212-L216 WeakPolarHBondContact O-CG 3.29Å; R212-L216 PolarHBondContact O-N 2.91Å; K213-L216 CarbonylContact O-C 3.51Å; K213-L216 PolarHBondContact O-N 3.49Å; L216-H219 CarbonylContact O-C 3.42Å; L216-H219 WeakPolarHBondContact O-CA 3.22Å; L216-H219 PolarHBondContact O-N 3.21Å; L216-M220 VanDerWaalsContact O-CB 3.32Å; L216-M220 WeakPolarHBondContact O-CB 3.4Å; L216-M220 WeakPolarHBondContact O-CG 3.33Å; L216-M220 PolarHBondContact O-N 3.23Å
217	F	46.4	Very low	42.8	Very low	141 Å²	141	103.6 Å²	103.6	62%	0.618	55%	0.548	S	S	*	.	H	α-helix	trans	-74.6	-29.5	176	-150.8	-88.1	0	0	0	110	K213 H219 M220 A221	K213-F217 WeakPolarHBondContact O-CA 3.36Å; K213-F217 WeakPolarHBondContact O-CB 3.33Å; K213-F217 PolarHBondContact O-N 2.9Å; F217-H219 VanDerWaalsContact C-N 3.3Å; F217-M220 PolarHBondContact O-N 2.87Å; F217-A221 HydrophobicContact CD1-CB 4.15Å; F217-A221 HydrophobicContact CE1-CB 4.39Å; F217-A221 WeakPolarHBondContact O-CA 3.22Å; F217-A221 WeakPolarHBondContact O-CB 3.38Å; F217-A221 PolarHBondContact O-N 3.29Å
218	N	40.3	Very low	41.6	Very low	121 Å²	121	102.7 Å²	102.7	65%	0.647	56%	0.556	S	S	*	*	H	α-helix	trans	-67.1	-33.3	166.7	-72.9	-7.9	0	0	0	111.7	T214 S215	T214-N218 WeakPolarHBondContact O-CB 3.3Å; T214-N218 PolarHBondContact O-N 3.22Å; T214-N218 PolarHBondContact O-ND2 2.92Å; T214-N218 PolarHBondContact O-OD1 2.85Å; S215-N218 PolarHBondContact O-N 3.01Å
219	H	37.8	Very low	40.6	Very low	139 Å²	139	108.1 Å²	108.1	64%	0.644	59%	0.589	S	S	*	*	H	α-helix	trans	-78.6	-26.3	172	-81.8	-66	0	0	0	114.3	S215 L216 F217 S222	S215-H219 PolarHBondContact O-CD2 3.32Å; S215-H219 VanDerWaalsContact O-CD2 3.31Å; S215-H219 PolarHBondContact O-N 2.9Å; S215-H219 VanDerWaalsContact O-N 3.12Å; L216-H219 CarbonylContact O-C 3.42Å; L216-H219 WeakPolarHBondContact O-CA 3.22Å; L216-H219 PolarHBondContact O-N 3.21Å; F217-H219 VanDerWaalsContact C-N 3.3Å; H219-S222 PolarHBondContact O-OG 2.9Å
220	M	28.7	Very low	40	Very low	122 Å²	122	112.4 Å²	112.4	60%	0.601	62%	0.619	S	S	*	*	H	α-helix	trans	-98.2	-19.4	179.6	-76.7	-176.8	-159.5	0	0	113.4	L216 F217 S222 M223	L216-M220 VanDerWaalsContact O-CB 3.32Å; L216-M220 WeakPolarHBondContact O-CB 3.4Å; L216-M220 WeakPolarHBondContact O-CG 3.33Å; L216-M220 PolarHBondContact O-N 3.23Å; F217-M220 PolarHBondContact O-N 2.87Å; M220-S222 PolarHBondContact O-N 2.89Å; M220-M223 CarbonylContact O-C 3.36Å; M220-M223 VanDerWaalsContact O-CA 3.29Å; M220-M223 WeakPolarHBondContact O-CA 3.44Å; M220-M223 WeakPolarHBondContact O-CB 3.11Å; M220-M223 PolarHBondContact O-N 2.95Å
221	A	33.2	Very low	39.2	Very low	67 Å²	67	111 Å²	111	55%	0.554	63%	0.627	S	S	*	*	T	Hydrogen-bonded Turn	trans	-69.3	-6.9	172.5	0	0	0	0	0	111.6	F217 M223	F217-A221 HydrophobicContact CD1-CB 4.15Å; F217-A221 HydrophobicContact CE1-CB 4.39Å; F217-A221 WeakPolarHBondContact O-CA 3.22Å; F217-A221 WeakPolarHBondContact O-CB 3.38Å; F217-A221 PolarHBondContact O-N 3.29Å; A221-M223 PolarHBondContact O-N 3.5Å
222	S	38.8	Very low	38.3	Very low	95 Å²	95	114 Å²	114	66%	0.664	64%	0.643	S	S	*	*	T	Hydrogen-bonded Turn	trans	-69.9	-3.4	157.8	74.6	0	0	0	0	113.3	H219 M220	H219-S222 PolarHBondContact O-OG 2.9Å; M220-S222 PolarHBondContact O-N 2.89Å
223	M	29.9	Very low	37.7	Very low	158 Å²	158	112.1 Å²	112.1	78%	0.778	64%	0.64	S	S	*	*	S	Bend	trans	-136.7	95.5	176.4	-65.4	-161.9	-161.2	0	0	110.8	M220 A221	M220-M223 CarbonylContact O-C 3.36Å; M220-M223 VanDerWaalsContact O-CA 3.29Å; M220-M223 WeakPolarHBondContact O-CA 3.44Å; M220-M223 WeakPolarHBondContact O-CB 3.11Å; M220-M223 PolarHBondContact O-N 2.95Å; A221-M223 PolarHBondContact O-N 3.5Å
224	G	27.4	Very low	37	Very low	70 Å²	70	113 Å²	113	72%	0.722	64%	0.644	S	S	*	*			trans	45.8	116.2	144.9	0	0	0	0	0	120.3
225	P	33.9	Very low	36.6	Very low	127 Å²	127	112.8 Å²	112.8	83%	0.825	65%	0.646	S	S	*	*			trans	-84.8	141	177.2	34.1	-30.2	0	0	0	112
226	R	31.1	Very low	36.2	Very low	252 Å²	252	119.7 Å²	119.7	95%	0.951	67%	0.667	S	S	*	*			trans	-134.8	133.9	165.4	-122.2	-179.8	165.3	-174.6	-4.8	111
227	E	28.2	Very low	36.4	Very low	187 Å²	187	119.4 Å²	119.4	87%	0.874	67%	0.666	S	S	*	*			trans	-88.9	159.9	-157.9	-61	169.7	139.3	0	0	115.3
228	A	29.5	Very low	36.4	Very low	90 Å²	90	118.8 Å²	118.8	74%	0.744	66%	0.661	S	S	*	*			trans	63.7	90.2	140.7	0	0	0	0	0	122
229	V	33.5	Very low	36.7	Very low	126 Å²	126	118.6 Å²	118.6	76%	0.764	66%	0.659	S	S	*	*			trans	-146.9	94	139.8	-177.2	0	0	0	0	108.2	A233	V229-A233 WeakPolarHBondContact O-CB 3.5Å
230	S	41.6	Very low	37.4	Very low	111 Å²	111	115.4 Å²	115.4	78%	0.776	65%	0.646	S	S	*	*			trans	-108.2	-1	-160.5	58.9	0	0	0	0	118.2
231	G	34.8	Very low	38.5	Very low	63 Å²	63	111.5 Å²	111.5	65%	0.649	63%	0.63	S	S	*	*	S	Bend	trans	-96.5	-63.9	-178.1	0	0	0	0	0	114.5	A233 K234	G231-A233 VanDerWaalsContact C-N 3.32Å; G231-K234 PolarHBondContact O-N 3.42Å
232	L	34.1	Very low	39.1	Very low	148 Å²	148	112.7 Å²	112.7	78%	0.775	63%	0.626	S	S	*	*	S	Bend	trans	-79.2	-18.8	-178.4	-162.7	66.1	0	0	0	112.8	K234	L232-K234 VanDerWaalsContact C-N 3.32Å
233	A	41.1	Very low	39.4	Very low	24 Å²	24	115.5 Å²	115.5	20%	0.198	62%	0.622	C	S	.	*	H	α-helix	trans	-60.3	-41.3	171.2	0	0	0	0	0	110.7	V229 G231 S235 R236 D237	V229-A233 WeakPolarHBondContact O-CB 3.5Å; G231-A233 VanDerWaalsContact C-N 3.32Å; A233-S235 PolarHBondContact O-N 2.94Å; A233-R236 CarbonylContact O-C 3.56Å; A233-R236 WeakPolarHBondContact O-CA 3.2Å; A233-R236 PolarHBondContact O-N 3.21Å; A233-R236 VanDerWaalsContact O-N 3.12Å; A233-D237 WeakPolarHBondContact O-CA 3.33Å; A233-D237 VanDerWaalsContact O-CB 3.25Å; A233-D237 WeakPolarHBondContact O-CB 3.28Å; A233-D237 PolarHBondContact O-N 2.99Å; A233-D237 VanDerWaalsContact O-OD2 3.07Å
234	K	37.1	Very low	40.3	Very low	133 Å²	133	111.2 Å²	111.2	58%	0.578	60%	0.6	S	S	*	*	H	α-helix	trans	-58.9	-41.6	-171.9	-144.6	173.1	-172.7	174.2	0	114.5	G231 L232 D237 Y238	G231-K234 PolarHBondContact O-N 3.42Å; L232-K234 VanDerWaalsContact C-N 3.32Å; K234-D237 WeakPolarHBondContact O-CB 3.34Å; K234-D237 PolarHBondContact O-N 3.42Å; K234-Y238 HydrophobicContact CG-CE2 4.13Å; K234-Y238 WeakPolarHBondContact O-CD2 3.31Å; K234-Y238 PolarHBondContact O-N 3.34Å
235	S	42.3	Very low	41.3	Very low	76 Å²	76	108.7 Å²	108.7	53%	0.531	57%	0.571	S	S	.	*	H	α-helix	trans	-73	-41.8	176.5	177.1	0	0	0	0	112.4	A233 D237 Y238 L239	A233-S235 PolarHBondContact O-N 2.94Å; S235-D237 PolarHBondContact O-N 3Å; S235-Y238 PolarHBondContact O-N 3.08Å; S235-L239 PolarHBondContact O-N 3.32Å
236	R	42.3	Very low	41.7	Very low	178 Å²	178	112 Å²	112	67%	0.672	57%	0.567	S	S	*	*	H	α-helix	trans	-61.3	-35.5	169	-95	176.5	99.8	177.4	5.1	110.9	A233 L239 L240	A233-R236 CarbonylContact O-C 3.56Å; A233-R236 WeakPolarHBondContact O-CA 3.2Å; A233-R236 PolarHBondContact O-N 3.21Å; A233-R236 VanDerWaalsContact O-N 3.12Å; R236-L239 PolarHBondContact O-N 3.28Å; R236-L240 HydrophobicContact CB-CD1 4.34Å; R236-L240 WeakPolarHBondContact O-CA 3.35Å; R236-L240 WeakPolarHBondContact O-CB 3.39Å; R236-L240 WeakPolarHBondContact O-CD1 3.22Å; R236-L240 WeakPolarHBondContact O-CG 3.49Å; R236-L240 PolarHBondContact O-N 3.48Å
237	D	51.8	Low	42.5	Very low	80 Å²	80	103.1 Å²	103.1	43%	0.428	54%	0.535	S	S	.	.	H	α-helix	trans	-69.9	-36	178.2	-66.7	-28.6	0	0	0	109.9	A233 K234 S235 T241	A233-D237 WeakPolarHBondContact O-CA 3.33Å; A233-D237 VanDerWaalsContact O-CB 3.25Å; A233-D237 WeakPolarHBondContact O-CB 3.28Å; A233-D237 PolarHBondContact O-N 2.99Å; A233-D237 VanDerWaalsContact O-OD2 3.07Å; K234-D237 WeakPolarHBondContact O-CB 3.34Å; K234-D237 PolarHBondContact O-N 3.42Å; S235-D237 PolarHBondContact O-N 3Å; D237-T241 WeakPolarHBondContact O-CA 3.31Å; D237-T241 WeakPolarHBondContact O-CB 3.07Å; D237-T241 WeakPolarHBondContact O-CG2 3.42Å; D237-T241 PolarHBondContact O-N 2.89Å; D237-T241 PolarHBondContact O-OG1 2.97Å
238	Y	46.4	Very low	43.3	Very low	128 Å²	128	96.9 Å²	96.9	50%	0.502	51%	0.506	S	S	.	.	H	α-helix	trans	-64.9	-47.4	170.3	-79.2	-67.9	0	0	0	112.1	K234 S235 T241 L242	K234-Y238 HydrophobicContact CG-CE2 4.13Å; K234-Y238 WeakPolarHBondContact O-CD2 3.31Å; K234-Y238 PolarHBondContact O-N 3.34Å; S235-Y238 PolarHBondContact O-N 3.08Å; Y238-T241 VanDerWaalsContact CA-OG1 3.26Å; Y238-T241 WeakPolarHBondContact CA-OG1 3.09Å; Y238-T241 PolarHBondContact O-N 3.48Å; Y238-T241 PolarHBondContact O-OG1 3.19Å; Y238-L242 VanDerWaalsContact O-CB 3.31Å; Y238-L242 WeakPolarHBondContact O-CB 3.5Å; Y238-L242 VanDerWaalsContact O-CG 3.24Å; Y238-L242 WeakPolarHBondContact O-CG 3.48Å; Y238-L242 PolarHBondContact O-N 3.3Å
239	L	47.1	Very low	44	Very low	116 Å²	116	93.6 Å²	93.6	61%	0.607	48%	0.475	S	S	*	.	H	α-helix	trans	-69.6	-35	178	-71.2	175.8	0	0	0	112.6	S235 R236 R243	S235-L239 PolarHBondContact O-N 3.32Å; R236-L239 PolarHBondContact O-N 3.28Å; L239-R243 WeakPolarHBondContact O-CB 3.24Å; L239-R243 PolarHBondContact O-N 3.09Å
240	L	53.1	Low	44.5	Very low	72 Å²	72	90 Å²	90	38%	0.377	45%	0.454	S	S	.	.	H	α-helix	trans	-72.3	-39.6	174.9	-72	169.9	0	0	0	110.5	R236 R243 E244	R236-L240 HydrophobicContact CB-CD1 4.34Å; R236-L240 WeakPolarHBondContact O-CA 3.35Å; R236-L240 WeakPolarHBondContact O-CB 3.39Å; R236-L240 WeakPolarHBondContact O-CD1 3.22Å; R236-L240 WeakPolarHBondContact O-CG 3.49Å; R236-L240 PolarHBondContact O-N 3.48Å; L240-R243 PolarHBondContact O-N 2.94Å; L240-E244 WeakPolarHBondContact O-CA 3.21Å; L240-E244 WeakPolarHBondContact O-CB 3.04Å; L240-E244 VanDerWaalsContact O-CG 3.22Å; L240-E244 WeakPolarHBondContact O-CG 3.39Å; L240-E244 PolarHBondContact O-N 3.1Å
241	T	50.4	Low	44.7	Very low	41 Å²	41	93 Å²	93	25%	0.252	45%	0.448	S	S	.	.	H	α-helix	trans	-66.7	-38.1	171.8	50	0	0	0	0	110.7	D237 Y238 T245	D237-T241 WeakPolarHBondContact O-CA 3.31Å; D237-T241 WeakPolarHBondContact O-CB 3.07Å; D237-T241 WeakPolarHBondContact O-CG2 3.42Å; D237-T241 PolarHBondContact O-N 2.89Å; D237-T241 PolarHBondContact O-OG1 2.97Å; Y238-T241 VanDerWaalsContact CA-OG1 3.26Å; Y238-T241 WeakPolarHBondContact CA-OG1 3.09Å; Y238-T241 PolarHBondContact O-N 3.48Å; Y238-T241 PolarHBondContact O-OG1 3.19Å; T241-T245 WeakPolarHBondContact O-CA 3.38Å; T241-T245 WeakPolarHBondContact O-CB 3.25Å; T241-T245 WeakPolarHBondContact O-CG2 3.02Å; T241-T245 PolarHBondContact O-N 2.99Å; T241-T245 PolarHBondContact O-OG1 2.97Å
242	L	46.1	Very low	45.3	Very low	92 Å²	92	92.7 Å²	92.7	48%	0.482	43%	0.43	S	S	.	.	H	α-helix	trans	-64.7	-41	171.1	-75.1	171.1	0	0	0	112.1	Y238 T245 W246	Y238-L242 VanDerWaalsContact O-CB 3.31Å; Y238-L242 WeakPolarHBondContact O-CB 3.5Å; Y238-L242 VanDerWaalsContact O-CG 3.24Å; Y238-L242 WeakPolarHBondContact O-CG 3.48Å; Y238-L242 PolarHBondContact O-N 3.3Å; L242-T245 VanDerWaalsContact C-OG1 3.22Å; L242-T245 WeakPolarHBondContact CA-OG1 3.35Å; L242-T245 PolarHBondContact O-OG1 2.91Å; L242-W246 WeakPolarHBondContact O-CB 3.33Å; L242-W246 PolarHBondContact O-N 2.74Å
243	R	45.6	Very low	45.8	Very low	153 Å²	153	86.9 Å²	86.9	58%	0.577	40%	0.399	S	S	*	.	H	α-helix	trans	-69.7	-42.8	177.4	-176	179.3	-172.9	-174.6	1.3	112	L239 L240 W246 K247	L239-R243 WeakPolarHBondContact O-CB 3.24Å; L239-R243 PolarHBondContact O-N 3.09Å; L240-R243 PolarHBondContact O-N 2.94Å; R243-W246 PolarHBondContact O-N 3.02Å; R243-K247 HydrophobicContact CG-CD 4.45Å; R243-K247 VanDerWaalsContact O-CB 3.25Å; R243-K247 WeakPolarHBondContact O-CB 3.47Å; R243-K247 VanDerWaalsContact O-CG 3.23Å; R243-K247 WeakPolarHBondContact O-CG 3.32Å; R243-K247 PolarHBondContact O-N 3.46Å
244	E	48.4	Very low	46	Very low	69 Å²	69	87.3 Å²	87.3	32%	0.322	40%	0.396	S	S	.	.	H	α-helix	trans	-72.7	-35.1	177.8	-69.2	-52.5	132	0	0	110.8	L240 K247 Q248	L240-E244 WeakPolarHBondContact O-CA 3.21Å; L240-E244 WeakPolarHBondContact O-CB 3.04Å; L240-E244 VanDerWaalsContact O-CG 3.22Å; L240-E244 WeakPolarHBondContact O-CG 3.39Å; L240-E244 PolarHBondContact O-N 3.1Å; E244-K247 CarbonylContact O-C 3.57Å; E244-K247 IonicContact OE1-NZ 3.13Å; E244-K247 PolarHBondContact OE1-NZ 2.89Å; E244-Q248 WeakPolarHBondContact O-CA 3.14Å; E244-Q248 WeakPolarHBondContact O-CB 3.25Å; E244-Q248 WeakPolarHBondContact O-CG 3.3Å; E244-Q248 PolarHBondContact O-N 2.94Å
245	T	49.6	Very low	46.1	Very low	17 Å²	17	82.4 Å²	82.4	10%	0.104	38%	0.384	C	S	.	.	H	α-helix	trans	-65.7	-43.6	169.7	50.4	0	0	0	0	111.1	L205 C209 T241 L242 Q248 H249	L205-T245 HydrophobicContact CD2-CG2 4.09Å; C209-T245 WeakPolarHBondContact SG-CG2 3.34Å; T241-T245 WeakPolarHBondContact O-CA 3.38Å; T241-T245 WeakPolarHBondContact O-CB 3.25Å; T241-T245 WeakPolarHBondContact O-CG2 3.02Å; T241-T245 PolarHBondContact O-N 2.99Å; T241-T245 PolarHBondContact O-OG1 2.97Å; L242-T245 VanDerWaalsContact C-OG1 3.22Å; L242-T245 WeakPolarHBondContact CA-OG1 3.35Å; L242-T245 PolarHBondContact O-OG1 2.91Å; T245-Q248 PolarHBondContact O-N 3.44Å; T245-H249 WeakPolarHBondContact O-CB 3.4Å; T245-H249 PolarHBondContact O-N 3.07Å
246	W	42.2	Very low	46.2	Very low	196 Å²	196	84.3 Å²	84.3	74%	0.742	39%	0.394	S	S	*	.	H	α-helix	trans	-65.9	-42.4	176.8	-157.2	70.9	0	0	0	111.1	L242 R243 T250	L242-W246 WeakPolarHBondContact O-CB 3.33Å; L242-W246 PolarHBondContact O-N 2.74Å; R243-W246 PolarHBondContact O-N 3.02Å; W246-T250 VanDerWaalsContact O-CB 3.23Å; W246-T250 WeakPolarHBondContact O-CB 3.37Å; W246-T250 PolarHBondContact O-N 3.48Å; W246-T250 PolarHBondContact O-OG1 3.07Å
247	K	46.6	Very low	46.1	Very low	66 Å²	66	83.7 Å²	83.7	29%	0.287	40%	0.404	S	S	.	.	H	α-helix	trans	-64.3	-37.8	171.7	-78.3	177.8	-171.2	167.9	0	112.1	R243 E244 T250 R251	R243-K247 HydrophobicContact CG-CD 4.45Å; R243-K247 VanDerWaalsContact O-CB 3.25Å; R243-K247 WeakPolarHBondContact O-CB 3.47Å; R243-K247 VanDerWaalsContact O-CG 3.23Å; R243-K247 WeakPolarHBondContact O-CG 3.32Å; R243-K247 PolarHBondContact O-N 3.46Å; E244-K247 CarbonylContact O-C 3.57Å; E244-K247 IonicContact OE1-NZ 3.13Å; E244-K247 PolarHBondContact OE1-NZ 2.89Å; K247-T250 CarbonylContact O-C 3.48Å; K247-T250 PolarHBondContact O-N 3.43Å; K247-R251 WeakPolarHBondContact O-CA 3.38Å; K247-R251 WeakPolarHBondContact O-CB 3.42Å; K247-R251 WeakPolarHBondContact O-CG 3.47Å; K247-R251 PolarHBondContact O-N 2.56Å
248	Q	46.3	Very low	46	Very low	56 Å²	56	83.5 Å²	83.5	26%	0.262	41%	0.413	S	S	.	.	H	α-helix	trans	-71.7	-44.2	178.6	-79.7	170.5	4.3	0	0	110.8	E244 T245 T250 R251 Q252	E244-Q248 WeakPolarHBondContact O-CA 3.14Å; E244-Q248 WeakPolarHBondContact O-CB 3.25Å; E244-Q248 WeakPolarHBondContact O-CG 3.3Å; E244-Q248 PolarHBondContact O-N 2.94Å; T245-Q248 PolarHBondContact O-N 3.44Å; Q248-T250 VanDerWaalsContact C-N 3.28Å; Q248-T250 PolarHBondContact O-N 3.34Å; Q248-R251 PolarHBondContact O-N 3.08Å; Q248-Q252 VanDerWaalsContact O-CB 3.23Å; Q248-Q252 WeakPolarHBondContact O-CB 3.34Å; Q248-Q252 WeakPolarHBondContact O-CG 3.03Å; Q248-Q252 PolarHBondContact O-N 3.46Å
249	H	43.9	Very low	46.4	Very low	20 Å²	20	80.9 Å²	80.9	9%	0.093	41%	0.407	C	S	.	.	H	α-helix	trans	-52.7	-50.8	167.4	-128.3	-75.5	0	0	0	109.2	T245 R251 L253 E288	T245-H249 WeakPolarHBondContact O-CB 3.4Å; T245-H249 PolarHBondContact O-N 3.07Å; H249-R251 PolarHBondContact O-N 3.43Å; H249-L253 WeakPolarHBondContact O-CB 3.24Å; H249-L253 WeakPolarHBondContact O-CD1 3.29Å; H249-L253 WeakPolarHBondContact O-CG 3.39Å; H249-L253 PolarHBondContact O-N 3.25Å; H249-E288 IonicContact CE1-OE1 2.9Å; H249-E288 PolarHBondContact CE1-OE1 2.71Å; H249-E288 IonicContact CE1-OE2 3.58Å; H249-E288 PolarHBondContact CE1-OE2 2.86Å; H249-E288 IonicContact NE2-OE2 3.76Å; H249-E288 PolarHBondContact NE2-OE2 3.41Å
250	T	43.7	Very low	47	Very low	51 Å²	51	76.4 Å²	76.4	31%	0.313	39%	0.385	S	S	.	.	H	α-helix	trans	-68.4	-32.5	-177.9	-53.4	0	0	0	0	113.6	K144 W246 K247 Q248	K144-T250 PolarHBondContact NZ-O 2.86Å; K144-T250 VanDerWaalsContact NZ-O 3.15Å; W246-T250 VanDerWaalsContact O-CB 3.23Å; W246-T250 WeakPolarHBondContact O-CB 3.37Å; W246-T250 PolarHBondContact O-N 3.48Å; W246-T250 PolarHBondContact O-OG1 3.07Å; K247-T250 CarbonylContact O-C 3.48Å; K247-T250 PolarHBondContact O-N 3.43Å; Q248-T250 VanDerWaalsContact C-N 3.28Å; Q248-T250 PolarHBondContact O-N 3.34Å
251	R	45.2	Very low	47.4	Very low	175 Å²	175	79 Å²	79	66%	0.66	40%	0.404	S	S	*	.	H	α-helix	trans	-80.3	-45.8	179.9	-82.1	179.8	172	-174.3	-3.8	111.4	K247 Q248 H249 L253 Y254	K247-R251 WeakPolarHBondContact O-CA 3.38Å; K247-R251 WeakPolarHBondContact O-CB 3.42Å; K247-R251 WeakPolarHBondContact O-CG 3.47Å; K247-R251 PolarHBondContact O-N 2.56Å; Q248-R251 PolarHBondContact O-N 3.08Å; H249-R251 PolarHBondContact O-N 3.43Å; R251-L253 VanDerWaalsContact C-N 3.35Å; R251-Y254 PolarHBondContact O-N 3.38Å
252	Q	47.7	Very low	48.2	Very low	56 Å²	56	78.9 Å²	78.9	26%	0.262	40%	0.4	S	S	.	.	H	α-helix	trans	-73.8	-26.5	178.3	-65.8	-174.7	-73.7	0	0	112.5	Q248 Y254 W284	Q248-Q252 VanDerWaalsContact O-CB 3.23Å; Q248-Q252 WeakPolarHBondContact O-CB 3.34Å; Q248-Q252 WeakPolarHBondContact O-CG 3.03Å; Q248-Q252 PolarHBondContact O-N 3.46Å; Q252-Y254 VanDerWaalsContact C-N 3.27Å; Q252-Y254 PolarHBondContact O-N 2.85Å; Q252-W284 VanDerWaalsContact CD-NE1 3.34Å; Q252-W284 VanDerWaalsContact OE1-NE1 3.1Å
253	L	45.1	Very low	48.9	Very low	26 Å²	26	76.8 Å²	76.8	14%	0.136	40%	0.396	C	S	.	.	H	α-helix	trans	-61.3	-31.8	174.3	-83.8	164.8	0	0	0	112.3	H249 R251	H249-L253 WeakPolarHBondContact O-CB 3.24Å; H249-L253 WeakPolarHBondContact O-CD1 3.29Å; H249-L253 WeakPolarHBondContact O-CG 3.39Å; H249-L253 PolarHBondContact O-N 3.25Å; R251-L253 VanDerWaalsContact C-N 3.35Å
254	Y	45.2	Very low	50.1	Low	32 Å²	32	73.2 Å²	73.2	13%	0.125	39%	0.394	C	S	.	.	S	Bend	trans	-157.3	65.8	-168.9	-73	-69.2	0	0	0	116.7	F80 E81 K144 R251 Q252 H337	F80-Y254 WeakPolarHBondContact CD1-OH 3.25Å; E81-Y254 HydrophobicContact CG-CE2 3.92Å; E81-Y254 WeakPolarHBondContact CG-OH 3.48Å; E81-Y254 VanDerWaalsContact OE1-CE2 3.22Å; E81-Y254 WeakPolarHBondContact OE1-CE2 3.41Å; E81-Y254 VanDerWaalsContact OE1-CZ 3.23Å; E81-Y254 PolarHBondContact OE1-OH 2.97Å; K144-Y254 WeakPolarHBondContact CE-O 3.32Å; K144-Y254 VanDerWaalsContact NZ-C 3.31Å; K144-Y254 PolarHBondContact NZ-O 3.29Å; R251-Y254 PolarHBondContact O-N 3.38Å; Q252-Y254 VanDerWaalsContact C-N 3.27Å; Q252-Y254 PolarHBondContact O-N 2.85Å; Y254-H337 AromaticContact CD1-NE2 3.85Å; Y254-H337 AromaticContact CE1-CE1 3.51Å; Y254-H337 AromaticContact CE1-NE2 3.03Å; Y254-H337 WeakPolarHBondContact CE1-NE2 3.23Å; Y254-H337 AromaticContact CZ-NE2 3.54Å; Y254-H337 PolarHBondContact OH-NE2 2.92Å
255	G	39.5	Very low	51	Low	31 Å²	31	72.1 Å²	72.1	32%	0.32	39%	0.393	S	S	.	.			trans	-135.6	105.4	169.6	0	0	0	0	0	111.3	D257 A258	G255-D257 PolarHBondContact O-N 3.3Å; G255-A258 PolarHBondContact O-N 3.19Å; G255-A258 VanDerWaalsContact O-N 3.16Å
256	P	44.1	Very low	52.1	Low	115 Å²	115	76.4 Å²	76.4	75%	0.747	42%	0.415	S	S	*	.	G	3₁₀ helix	trans	-55.9	-26.4	164.1	22.8	-30.9	0	0	0	111.4	A258 M259	P256-A258 PolarHBondContact O-N 3.43Å; P256-A258 VanDerWaalsContact O-N 3.09Å; P256-M259 PolarHBondContact O-N 3.28Å; P256-M259 VanDerWaalsContact O-N 3.14Å
257	D	40.1	Very low	54	Low	165 Å²	165	69 Å²	69	88%	0.882	39%	0.393	S	S	*	.	G	3₁₀ helix	trans	-67.9	-4.2	177.3	-60.2	-30.6	0	0	0	115.3	G255	G255-D257 PolarHBondContact O-N 3.3Å
258	A	49.4	Very low	55.8	Low	76 Å²	76	66.6 Å²	66.6	63%	0.628	38%	0.384	S	S	*	.	G	3₁₀ helix	trans	-117.9	14.7	174.9	0	0	0	0	0	112.6	G255 P256 P260	G255-A258 PolarHBondContact O-N 3.19Å; G255-A258 VanDerWaalsContact O-N 3.16Å; P256-A258 PolarHBondContact O-N 3.43Å; P256-A258 VanDerWaalsContact O-N 3.09Å; A258-P260 WeakPolarHBondContact O-CD 3.4Å
259	M	55.7	Low	57.6	Low	74 Å²	74	67.7 Å²	67.7	37%	0.365	40%	0.398	S	S	.	.	S	Bend	trans	-64.6	121.8	171.2	-167.3	168.3	134.8	0	0	107.9	P256 T261	P256-M259 PolarHBondContact O-N 3.28Å; P256-M259 VanDerWaalsContact O-N 3.14Å; M259-T261 PolarHBondContact O-N 3.18Å
260	P	59.5	Low	59.6	Low	22 Å²	22	71 Å²	71	14%	0.143	42%	0.415	C	S	.	.	P	Polyproline II helix	trans	-58.4	129.7	178.9	3.7	-2.2	0	0	0	108.7	A258 F277 L278 Y343 L346	A258-P260 WeakPolarHBondContact O-CD 3.4Å; P260-F277 HydrophobicContact CB-CD1 4.39Å; P260-F277 HydrophobicContact CB-CE1 3.9Å; P260-F277 HydrophobicContact CG-CE1 4.05Å; P260-L278 HydrophobicContact CB-CD2 3.94Å; P260-L278 HydrophobicContact CG-CD2 3.71Å; P260-Y343 HydrophobicContact CG-CE2 4.28Å; P260-L346 HydrophobicContact CB-CD2 3.87Å; P260-L346 HydrophobicContact CG-CD2 3.63Å; P260-L346 WeakPolarHBondContact O-CD2 3.4Å
261	T	61.3	Low	61.6	Low	126 Å²	126	68.8 Å²	68.8	77%	0.773	40%	0.402	S	S	*	.	P	Polyproline II helix	trans	-84.8	134.6	175.5	46.6	0	0	0	0	108.9	M259 A263	M259-T261 PolarHBondContact O-N 3.18Å; T261-A263 PolarHBondContact O-N 2.84Å
262	H	67.4	Low	63.6	Low	39 Å²	39	61.7 Å²	61.7	18%	0.181	38%	0.375	C	S	.	.			trans	-73.9	115.4	172.8	-172.6	-90.2	0	0	0	109.1	C264 E274 L346 H353	H262-C264 VanDerWaalsContact CE1-SG 3.51Å; H262-C264 PolarHBondContact ND1-N 3.49Å; H262-C264 PolarHBondContact ND1-SG 3.49Å; H262-C264 PolarHBondContact O-N 3.09Å; H262-E274 WeakPolarHBondContact CA-OE1 3.43Å; H262-E274 IonicContact CD2-OE1 2.81Å; H262-E274 PolarHBondContact CD2-OE1 3.42Å; H262-E274 IonicContact CG-OE1 3.87Å; H262-E274 IonicContact NE2-OE1 2.84Å; H262-L346 HydrophobicContact CB-CD1 3.5Å; H262-L346 VanDerWaalsContact CB-CD1 3.5Å; H262-H353 AromaticContact CE1-CD2 3.32Å; H262-H353 PolarHBondContact CE1-CD2 2.81Å; H262-H353 AromaticContact CE1-NE2 3.34Å; H262-H353 PolarHBondContact CE1-NE2 3.35Å; H262-H353 VanDerWaalsContact CE1-NE2 3.34Å; H262-H353 AromaticContact NE2-CD2 3.31Å; H262-H353 PolarHBondContact NE2-CD2 2.83Å; H262-H353 VanDerWaalsContact NE2-CD2 3.31Å; H262-H353 AromaticContact NE2-NE2 3.83Å
263	A	60.7	Low	65.4	Low	47 Å²	47	61.7 Å²	61.7	39%	0.388	38%	0.381	S	S	.	.			trans	-85.3	107.3	168.9	0	0	0	0	0	106.3	T261 C265	T261-A263 PolarHBondContact O-N 2.84Å; A263-C265 HydrophobicContact CB-CB 4.48Å; A263-C265 WeakPolarHBondContact CB-SG 3.08Å; A263-C265 PolarHBondContact O-N 2.78Å
264	C	70.3	Confident	67.3	Low	79 Å²	79	61.9 Å²	61.9	53%	0.534	38%	0.382	S	S	.	.			trans	-69.3	55.1	172.2	-70.3	0	0	0	0	111	H66 H262	H66-C264 PolarHBondContact CD2-SG 3.35Å; H262-C264 VanDerWaalsContact CE1-SG 3.51Å; H262-C264 PolarHBondContact ND1-N 3.49Å; H262-C264 PolarHBondContact ND1-SG 3.49Å; H262-C264 PolarHBondContact O-N 3.09Å
265	C	68.1	Low	69.4	Low	45 Å²	45	60.4 Å²	60.4	30%	0.304	38%	0.376	S	S	.	.			trans	-82.7	144.8	-178.4	-70.4	0	0	0	0	109.8	A263 L270	A263-C265 HydrophobicContact CB-CB 4.48Å; A263-C265 WeakPolarHBondContact CB-SG 3.08Å; A263-C265 PolarHBondContact O-N 2.78Å; C265-L270 HydrophobicContact CB-CD1 4.31Å
266	L	72.9	Confident	71.7	Confident	108 Å²	108	62.6 Å²	62.6	57%	0.565	38%	0.378	S	S	*	.			trans	-90.7	-0.5	178.9	-70.8	150.3	0	0	0	112.7	V61 P268	V61-L266 HydrophobicContact CB-CD2 3.89Å; V61-L266 HydrophobicContact CG1-CD2 3.27Å; L266-P268 WeakPolarHBondContact O-CD 3.34Å
267	S	82	Confident	73.7	Confident	40 Å²	40	62.5 Å²	62.5	28%	0.28	37%	0.366	S	S	.	.			trans	-86.1	123.1	-177.5	49.8	0	0	0	0	111.9	S269 L270 I271	S267-S269 VanDerWaalsContact C-N 3.33Å; S267-S269 PolarHBondContact O-N 2.91Å; S267-L270 PolarHBondContact O-N 2.49Å; S267-L270 WeakPolarHBondContact OG-CB 3.3Å; S267-L270 WeakPolarHBondContact OG-CD1 3.33Å; S267-L270 WeakPolarHBondContact OG-CG 3.25Å; S267-I271 WeakPolarHBondContact O-CG1 3.41Å; S267-I271 PolarHBondContact O-N 3.1Å
268	P	83.8	Confident	76	Confident	16 Å²	16	54.7 Å²	54.7	10%	0.104	32%	0.324	C	S	.	.	H	α-helix	trans	-58.6	-38.2	-178.3	-31.4	40.1	0	0	0	114.7	L266 I271 R272 E375 E376 V400	L266-P268 WeakPolarHBondContact O-CD 3.34Å; P268-I271 PolarHBondContact O-N 3.14Å; P268-R272 WeakPolarHBondContact O-CG 3.38Å; P268-R272 PolarHBondContact O-N 2.99Å; P268-R272 VanDerWaalsContact O-N 3.15Å; P268-E375 WeakPolarHBondContact CB-O 3.2Å; P268-E376 WeakPolarHBondContact CG-O 3.4Å; P268-V400 HydrophobicContact CB-CG1 3.7Å; P268-V400 HydrophobicContact CB-CG2 4.16Å; P268-V400 HydrophobicContact CG-CG2 4.36Å; P268-V400 VanDerWaalsContact O-CG1 3.3Å; P268-V400 WeakPolarHBondContact O-CG1 3.12Å
269	S	84.8	Confident	77.8	Confident	79 Å²	79	52.5 Å²	52.5	55%	0.552	30%	0.3	S	S	*	.	H	α-helix	trans	-66.1	-39.3	179.9	53.1	0	0	0	0	112.9	S267 R272 S273	S267-S269 VanDerWaalsContact C-N 3.33Å; S267-S269 PolarHBondContact O-N 2.91Å; S269-R272 PolarHBondContact O-N 2.64Å; S269-S273 PolarHBondContact O-N 2.99Å; S269-S273 VanDerWaalsContact O-N 3.1Å; S269-S273 PolarHBondContact O-OG 3.04Å
270	L	85.8	Confident	79.1	Confident	88 Å²	88	51.8 Å²	51.8	46%	0.461	30%	0.296	S	S	.	.	H	α-helix	trans	-70.4	-38.6	177	-64.3	-176.4	0	0	0	111.8	C265 S267 R272 S273 E274	C265-L270 HydrophobicContact CB-CD1 4.31Å; S267-L270 PolarHBondContact O-N 2.49Å; S267-L270 WeakPolarHBondContact OG-CB 3.3Å; S267-L270 WeakPolarHBondContact OG-CD1 3.33Å; S267-L270 WeakPolarHBondContact OG-CG 3.25Å; L270-R272 VanDerWaalsContact C-N 3.31Å; L270-R272 PolarHBondContact O-N 3.23Å; L270-S273 WeakPolarHBondContact CA-OG 3.16Å; L270-S273 PolarHBondContact O-N 3.25Å; L270-S273 PolarHBondContact O-OG 2.85Å; L270-E274 VanDerWaalsContact O-CB 3.32Å; L270-E274 WeakPolarHBondContact O-CB 3.4Å; L270-E274 PolarHBondContact O-N 3.34Å
271	I	84.8	Confident	80.3	Confident	5 Å²	5	51.5 Å²	51.5	3%	0.026	29%	0.294	C	S	.	.	H	α-helix	trans	-60.9	-42.5	175.9	-66.3	163.1	0	0	0	110.4	S267 P268 V275 H353 M378 V400	S267-I271 WeakPolarHBondContact O-CG1 3.41Å; S267-I271 PolarHBondContact O-N 3.1Å; P268-I271 PolarHBondContact O-N 3.14Å; I271-V275 WeakPolarHBondContact O-CB 3.45Å; I271-V275 VanDerWaalsContact O-CG2 3.32Å; I271-V275 WeakPolarHBondContact O-CG2 3.08Å; I271-V275 PolarHBondContact O-N 3.03Å; I271-H353 HydrophobicContact CD1-CB 4.2Å; I271-H353 HydrophobicContact CG1-CB 4.41Å; I271-H353 HydrophobicContact CG2-CB 4.03Å; I271-M378 HydrophobicContact CD1-CE 3.77Å; I271-V400 HydrophobicContact CB-CG1 4.3Å; I271-V400 HydrophobicContact CD1-CG2 4.23Å; I271-V400 HydrophobicContact CG2-CG1 4.31Å
272	R	87.6	Confident	81.6	Confident	26 Å²	26	47.1 Å²	47.1	10%	0.098	26%	0.264	C	S	.	.	H	α-helix	trans	-64.7	-45.7	176.8	-67.5	-175.5	-163.3	110.7	9.4	111.9	P268 S269 L270 E274 V275 E276 E375 V400	P268-R272 WeakPolarHBondContact O-CG 3.38Å; P268-R272 PolarHBondContact O-N 2.99Å; P268-R272 VanDerWaalsContact O-N 3.15Å; S269-R272 PolarHBondContact O-N 2.64Å; L270-R272 VanDerWaalsContact C-N 3.31Å; L270-R272 PolarHBondContact O-N 3.23Å; R272-E274 VanDerWaalsContact C-N 3.34Å; R272-E274 PolarHBondContact O-N 2.8Å; R272-V275 PolarHBondContact O-N 3.49Å; R272-E276 WeakPolarHBondContact O-CG 3.25Å; R272-E276 PolarHBondContact O-N 3.49Å; R272-E375 VanDerWaalsContact CZ-O 3.26Å; R272-E375 PolarHBondContact NH1-O 2.76Å; R272-E375 PolarHBondContact NH2-O 2.9Å; R272-V400 HydrophobicContact CG-CG1 3.86Å; R272-V400 VanDerWaalsContact CZ-O 3.27Å; R272-V400 PolarHBondContact NE-O 3.06Å; R272-V400 PolarHBondContact NH2-O 2.85Å
273	S	85.1	Confident	82.6	Confident	56 Å²	56	49.3 Å²	49.3	39%	0.392	28%	0.277	S	S	.	.	H	α-helix	trans	-66.1	-36.5	179.6	64.5	0	0	0	0	112.5	S269 L270 E276 F277	S269-S273 PolarHBondContact O-N 2.99Å; S269-S273 VanDerWaalsContact O-N 3.1Å; S269-S273 PolarHBondContact O-OG 3.04Å; L270-S273 WeakPolarHBondContact CA-OG 3.16Å; L270-S273 PolarHBondContact O-N 3.25Å; L270-S273 PolarHBondContact O-OG 2.85Å; S273-E276 PolarHBondContact O-N 3.44Å; S273-F277 PolarHBondContact O-N 3.41Å
274	E	86	Confident	83.6	Confident	31 Å²	31	48.7 Å²	48.7	15%	0.145	27%	0.265	C	S	.	.	H	α-helix	trans	-61.8	-47.4	172.4	-178.3	177.6	178.6	0	0	111.5	H262 L270 R272 E276 F277 L278	H262-E274 WeakPolarHBondContact CA-OE1 3.43Å; H262-E274 IonicContact CD2-OE1 2.81Å; H262-E274 PolarHBondContact CD2-OE1 3.42Å; H262-E274 IonicContact CG-OE1 3.87Å; H262-E274 IonicContact NE2-OE1 2.84Å; L270-E274 VanDerWaalsContact O-CB 3.32Å; L270-E274 WeakPolarHBondContact O-CB 3.4Å; L270-E274 PolarHBondContact O-N 3.34Å; R272-E274 VanDerWaalsContact C-N 3.34Å; R272-E274 PolarHBondContact O-N 2.8Å; E274-E276 PolarHBondContact O-N 3.39Å; E274-F277 WeakPolarHBondContact O-CB 3.22Å; E274-F277 PolarHBondContact O-N 3.04Å; E274-L278 HydrophobicContact CG-CD1 4.04Å; E274-L278 HydrophobicContact CG-CG 4.43Å; E274-L278 WeakPolarHBondContact O-CB 3.31Å; E274-L278 WeakPolarHBondContact O-CG 3.28Å; E274-L278 PolarHBondContact O-N 2.94Å
275	V	88.1	Confident	84.5	Confident	0 Å²	0	46.8 Å²	46.8	0%	0	25%	0.247	C	C	.	.	H	α-helix	trans	-62	-41.8	177.2	166	0	0	0	0	111.6	I271 R272 F277 L278 K279 A350 L354 F411	I271-V275 WeakPolarHBondContact O-CB 3.45Å; I271-V275 VanDerWaalsContact O-CG2 3.32Å; I271-V275 WeakPolarHBondContact O-CG2 3.08Å; I271-V275 PolarHBondContact O-N 3.03Å; R272-V275 PolarHBondContact O-N 3.49Å; V275-F277 VanDerWaalsContact C-N 3.32Å; V275-F277 PolarHBondContact O-N 3.49Å; V275-L278 PolarHBondContact O-N 3.29Å; V275-K279 HydrophobicContact CG1-CD 3.82Å; V275-K279 HydrophobicContact CG1-CG 4.26Å; V275-K279 WeakPolarHBondContact O-CB 3.09Å; V275-K279 VanDerWaalsContact O-CG 3.25Å; V275-K279 WeakPolarHBondContact O-CG 3.34Å; V275-K279 PolarHBondContact O-N 3.39Å; V275-A350 HydrophobicContact CG2-CB 4.26Å; V275-L354 HydrophobicContact CG1-CD1 4.48Å; V275-L354 HydrophobicContact CG1-CD2 3.83Å; V275-L354 HydrophobicContact CG2-CB 4.16Å; V275-L354 HydrophobicContact CG2-CD1 4.17Å; V275-L354 HydrophobicContact CG2-CD2 4.14Å; V275-L354 HydrophobicContact CG2-CG 4.37Å; V275-F411 HydrophobicContact CG1-CD1 3.83Å; V275-F411 HydrophobicContact CG1-CD2 4.47Å; V275-F411 HydrophobicContact CG1-CE1 4Å; V275-F411 HydrophobicContact CG1-CG 4.08Å; V275-F411 HydrophobicContact CG1-CZ 4.4Å; V275-F411 HydrophobicContact CG2-CD1 4.44Å; V275-F411 HydrophobicContact CG2-CE1 3.99Å
276	E	87.8	Confident	85.4	Confident	78 Å²	78	47.6 Å²	47.6	36%	0.364	25%	0.246	S	C	.	.	H	α-helix	trans	-61.4	-42	175.6	-73.2	-48.3	112.6	0	0	111.9	R272 S273 E274 K279 M280 H408	R272-E276 WeakPolarHBondContact O-CG 3.25Å; R272-E276 PolarHBondContact O-N 3.49Å; S273-E276 PolarHBondContact O-N 3.44Å; E274-E276 PolarHBondContact O-N 3.39Å; E276-K279 PolarHBondContact O-N 2.9Å; E276-K279 WeakPolarHBondContact OE1-CD 3.24Å; E276-K279 IonicContact OE1-NZ 3.27Å; E276-K279 PolarHBondContact OE1-NZ 3.04Å; E276-K279 IonicContact OE2-NZ 3.56Å; E276-K279 PolarHBondContact OE2-NZ 3.41Å; E276-M280 WeakPolarHBondContact O-CB 3.48Å; E276-M280 PolarHBondContact O-N 2.95Å; E276-H408 IonicContact OE1-CD2 3.2Å; E276-H408 IonicContact OE1-NE2 3.92Å; E276-H408 PolarHBondContact OE1-NE2 2.85Å
277	F	86.2	Confident	86	Confident	113 Å²	113	45.2 Å²	45.2	50%	0.496	23%	0.231	S	C	.	.	H	α-helix	trans	-62.8	-46.7	174.3	179.6	-93.4	0	0	0	112	P260 S273 E274 V275 K279 M280 D281	P260-F277 HydrophobicContact CB-CD1 4.39Å; P260-F277 HydrophobicContact CB-CE1 3.9Å; P260-F277 HydrophobicContact CG-CE1 4.05Å; S273-F277 PolarHBondContact O-N 3.41Å; E274-F277 WeakPolarHBondContact O-CB 3.22Å; E274-F277 PolarHBondContact O-N 3.04Å; V275-F277 VanDerWaalsContact C-N 3.32Å; V275-F277 PolarHBondContact O-N 3.49Å; F277-K279 PolarHBondContact O-N 3.36Å; F277-M280 WeakPolarHBondContact O-CB 3.18Å; F277-M280 PolarHBondContact O-N 3.46Å; F277-D281 PolarHBondContact O-N 3.49Å
278	L	88	Confident	86.1	Confident	0 Å²	0	44 Å²	44	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-65.1	-37.6	179.5	-72.1	175.7	0	0	0	112.4	P260 E274 V275 D281 F282 L346 L347 A350 F411	P260-L278 HydrophobicContact CB-CD2 3.94Å; P260-L278 HydrophobicContact CG-CD2 3.71Å; E274-L278 HydrophobicContact CG-CD1 4.04Å; E274-L278 HydrophobicContact CG-CG 4.43Å; E274-L278 WeakPolarHBondContact O-CB 3.31Å; E274-L278 WeakPolarHBondContact O-CG 3.28Å; E274-L278 PolarHBondContact O-N 2.94Å; V275-L278 PolarHBondContact O-N 3.29Å; L278-D281 PolarHBondContact O-N 3.09Å; L278-F282 VanDerWaalsContact O-CB 3.3Å; L278-F282 WeakPolarHBondContact O-CB 3.46Å; L278-F282 PolarHBondContact O-N 2.85Å; L278-L346 HydrophobicContact CD1-CG 4.41Å; L278-L346 HydrophobicContact CD2-CD2 3.78Å; L278-L346 HydrophobicContact CD2-CG 4.08Å; L278-L347 HydrophobicContact CB-CD2 3.91Å; L278-L347 HydrophobicContact CD1-CD2 4.42Å; L278-L347 HydrophobicContact CD2-CD2 4.43Å; L278-L347 HydrophobicContact CG-CD2 4.49Å; L278-A350 HydrophobicContact CD1-CB 3.4Å; L278-A350 VanDerWaalsContact CD1-CB 3.4Å; L278-F411 HydrophobicContact CB-CE2 4.34Å; L278-F411 HydrophobicContact CB-CZ 4.29Å
279	K	87.6	Confident	86.4	Confident	31 Å²	31	43.4 Å²	43.4	14%	0.135	22%	0.217	C	C	.	.	H	α-helix	trans	-60.2	-47.2	172.4	-78.2	167.3	57.2	-160.1	0	111.3	V275 E276 F277 D281 F282 N283 S407 F411	V275-K279 HydrophobicContact CG1-CD 3.82Å; V275-K279 HydrophobicContact CG1-CG 4.26Å; V275-K279 WeakPolarHBondContact O-CB 3.09Å; V275-K279 VanDerWaalsContact O-CG 3.25Å; V275-K279 WeakPolarHBondContact O-CG 3.34Å; V275-K279 PolarHBondContact O-N 3.39Å; E276-K279 PolarHBondContact O-N 2.9Å; E276-K279 WeakPolarHBondContact OE1-CD 3.24Å; E276-K279 IonicContact OE1-NZ 3.27Å; E276-K279 PolarHBondContact OE1-NZ 3.04Å; E276-K279 IonicContact OE2-NZ 3.56Å; E276-K279 PolarHBondContact OE2-NZ 3.41Å; F277-K279 PolarHBondContact O-N 3.36Å; K279-D281 VanDerWaalsContact C-N 3.35Å; K279-F282 PolarHBondContact O-N 3.37Å; K279-N283 WeakPolarHBondContact O-CB 3.33Å; K279-N283 VanDerWaalsContact O-CG 3.24Å; K279-N283 PolarHBondContact O-N 3.41Å; K279-N283 PolarHBondContact O-ND2 3.34Å; K279-N283 VanDerWaalsContact O-ND2 3.16Å; K279-S407 PolarHBondContact NZ-OG 3.29Å; K279-F411 HydrophobicContact CD-CB 4.37Å; K279-F411 HydrophobicContact CD-CD2 4.23Å; K279-F411 HydrophobicContact CD-CG 4.46Å; K279-F411 HydrophobicContact CG-CB 4.34Å; K279-F411 HydrophobicContact CG-CD2 3.39Å; K279-F411 HydrophobicContact CG-CE2 3.93Å; K279-F411 HydrophobicContact CG-CG 4.08Å
280	M	83.2	Confident	86.7	Confident	58 Å²	58	44.1 Å²	44.1	29%	0.286	22%	0.215	S	C	.	.	H	α-helix	trans	-59.2	-47.3	177.4	-174	90.1	71	0	0	110.9	L211 E276 F277 W284	L211-M280 HydrophobicContact CB-SD 4.48Å; L211-M280 HydrophobicContact CD2-SD 3.81Å; L211-M280 HydrophobicContact CG-SD 4.47Å; E276-M280 WeakPolarHBondContact O-CB 3.48Å; E276-M280 PolarHBondContact O-N 2.95Å; F277-M280 WeakPolarHBondContact O-CB 3.18Å; F277-M280 PolarHBondContact O-N 3.46Å; M280-W284 WeakPolarHBondContact O-CB 3.24Å; M280-W284 PolarHBondContact O-N 3.36Å
281	D	84.2	Confident	86.8	Confident	16 Å²	16	41 Å²	41	9%	0.086	20%	0.2	C	C	.	.	H	α-helix	trans	-65.8	-44.1	180	-170.7	60.3	0	0	0	112.2	F277 L278 K279 W284 R285 Y343	F277-D281 PolarHBondContact O-N 3.49Å; L278-D281 PolarHBondContact O-N 3.09Å; K279-D281 VanDerWaalsContact C-N 3.35Å; D281-W284 WeakPolarHBondContact O-CB 3.21Å; D281-W284 PolarHBondContact O-N 3.07Å; D281-R285 WeakPolarHBondContact O-CG 3.36Å; D281-R285 PolarHBondContact O-N 2.98Å; D281-R285 IonicContact OD1-NE 3.22Å; D281-R285 IonicContact OD2-CZ 3.11Å; D281-R285 IonicContact OD2-NE 3.36Å; D281-R285 PolarHBondContact OD2-NE 2.75Å; D281-R285 IonicContact OD2-NH2 3.39Å; D281-R285 PolarHBondContact OD2-NH2 3Å; D281-Y343 WeakPolarHBondContact OD2-CE2 3.29Å; D281-Y343 PolarHBondContact OD2-OH 3.26Å
282	F	89.5	Confident	87	Confident	34 Å²	34	40.9 Å²	40.9	15%	0.149	20%	0.199	C	C	.	.	H	α-helix	trans	-60.5	-48.9	176.3	175.8	-97.9	0	0	0	111.3	L278 K279 W284 R285 M286 L339 Y343 L347 F415 I421	L278-F282 VanDerWaalsContact O-CB 3.3Å; L278-F282 WeakPolarHBondContact O-CB 3.46Å; L278-F282 PolarHBondContact O-N 2.85Å; K279-F282 PolarHBondContact O-N 3.37Å; F282-W284 VanDerWaalsContact C-N 3.26Å; F282-W284 PolarHBondContact O-N 3.47Å; F282-R285 PolarHBondContact O-N 2.85Å; F282-R285 VanDerWaalsContact O-N 3.16Å; F282-M286 HydrophobicContact CD1-CG 4Å; F282-M286 HydrophobicContact CD2-CG 4.44Å; F282-M286 HydrophobicContact CE1-CG 3.53Å; F282-M286 HydrophobicContact CE1-SD 4.27Å; F282-M286 HydrophobicContact CE2-CG 4.01Å; F282-M286 HydrophobicContact CE2-SD 3.97Å; F282-M286 HydrophobicContact CG-CG 4.44Å; F282-M286 HydrophobicContact CZ-CG 3.53Å; F282-M286 HydrophobicContact CZ-SD 3.65Å; F282-M286 WeakPolarHBondContact O-CG 3.24Å; F282-M286 PolarHBondContact O-N 2.86Å; F282-L339 HydrophobicContact CD2-CD2 3.9Å; F282-L339 HydrophobicContact CE2-CD1 3.99Å; F282-L339 HydrophobicContact CE2-CD2 3.96Å; F282-Y343 WeakPolarHBondContact CA-OH 3.45Å; F282-Y343 HydrophobicContact CD2-CE1 4.38Å; F282-Y343 PolarHBondContact N-OH 2.6Å; F282-L347 HydrophobicContact CD2-CD1 4.11Å; F282-F415 HydrophobicContact CD1-CZ 4.05Å; F282-F415 HydrophobicContact CD2-CE1 4.17Å; F282-F415 AromaticContact CD2-CZ 3.77Å; F282-F415 HydrophobicContact CD2-CZ 3.77Å; F282-F415 HydrophobicContact CE1-CZ 4.08Å; F282-F415 AromaticContact CE2-CE1 4Å; F282-F415 HydrophobicContact CE2-CE1 4Å; F282-F415 AromaticContact CE2-CZ 3.81Å; F282-F415 HydrophobicContact CE2-CZ 3.81Å; F282-F415 AromaticContact CG-CZ 3.9Å; F282-F415 HydrophobicContact CG-CZ 3.9Å; F282-F415 HydrophobicContact CZ-CE1 4.4Å; F282-F415 AromaticContact CZ-CZ 3.96Å; F282-F415 HydrophobicContact CZ-CZ 3.96Å; F282-I421 HydrophobicContact CE2-CD1 4.25Å
283	N	87.7	Confident	87.3	Confident	86 Å²	86	39.7 Å²	39.7	46%	0.46	19%	0.194	S	C	.	.	H	α-helix	trans	-60.1	-39.1	178	-74.8	-29.4	0	0	0	111.6	K279 M286 K287	K279-N283 WeakPolarHBondContact O-CB 3.33Å; K279-N283 VanDerWaalsContact O-CG 3.24Å; K279-N283 PolarHBondContact O-N 3.41Å; K279-N283 PolarHBondContact O-ND2 3.34Å; K279-N283 VanDerWaalsContact O-ND2 3.16Å; N283-M286 PolarHBondContact O-N 3.02Å; N283-K287 VanDerWaalsContact O-CB 3.23Å; N283-K287 WeakPolarHBondContact O-CB 3.18Å; N283-K287 WeakPolarHBondContact O-CG 3.37Å; N283-K287 PolarHBondContact O-N 3.42Å
284	W	82.6	Confident	87.6	Confident	34 Å²	34	40.7 Å²	40.7	13%	0.129	19%	0.194	C	C	.	.	H	α-helix	trans	-62.4	-46.1	174.6	170	-97	0	0	0	112.2	N208 Q252 M280 D281 F282 M286 K287 E288	N208-W284 HydrophobicContact CB-CE3 3.65Å; N208-W284 HydrophobicContact CB-CH2 4.45Å; N208-W284 HydrophobicContact CB-CZ3 3.28Å; N208-W284 VanDerWaalsContact ND2-CZ3 3.26Å; N208-W284 WeakPolarHBondContact ND2-CZ3 3.49Å; Q252-W284 VanDerWaalsContact CD-NE1 3.34Å; Q252-W284 VanDerWaalsContact OE1-NE1 3.1Å; M280-W284 WeakPolarHBondContact O-CB 3.24Å; M280-W284 PolarHBondContact O-N 3.36Å; D281-W284 WeakPolarHBondContact O-CB 3.21Å; D281-W284 PolarHBondContact O-N 3.07Å; F282-W284 VanDerWaalsContact C-N 3.26Å; F282-W284 PolarHBondContact O-N 3.47Å; W284-M286 PolarHBondContact O-N 2.89Å; W284-K287 WeakPolarHBondContact O-CB 3.29Å; W284-K287 PolarHBondContact O-N 3.39Å; W284-E288 PolarHBondContact O-N 2.87Å
285	R	87.9	Confident	87.9	Confident	39 Å²	39	39.6 Å²	39.6	15%	0.147	19%	0.189	C	C	.	.	H	α-helix	trans	-61.8	-43.9	176.4	-67.4	175	-168.9	-138.6	5.8	111.9	D281 F282 K287 E288 V289 L338 Y343	D281-R285 WeakPolarHBondContact O-CG 3.36Å; D281-R285 PolarHBondContact O-N 2.98Å; D281-R285 IonicContact OD1-NE 3.22Å; D281-R285 IonicContact OD2-CZ 3.11Å; D281-R285 IonicContact OD2-NE 3.36Å; D281-R285 PolarHBondContact OD2-NE 2.75Å; D281-R285 IonicContact OD2-NH2 3.39Å; D281-R285 PolarHBondContact OD2-NH2 3Å; F282-R285 PolarHBondContact O-N 2.85Å; F282-R285 VanDerWaalsContact O-N 3.16Å; R285-K287 VanDerWaalsContact C-N 3.34Å; R285-K287 PolarHBondContact O-N 3Å; R285-E288 WeakPolarHBondContact O-CB 3.49Å; R285-E288 PolarHBondContact O-N 3.42Å; R285-V289 VanDerWaalsContact O-CG2 3.31Å; R285-V289 WeakPolarHBondContact O-CG2 3.19Å; R285-V289 PolarHBondContact O-N 2.72Å; R285-L338 HydrophobicContact CB-CB 4.46Å; R285-L338 WeakPolarHBondContact CD-O 3.23Å; R285-L338 PolarHBondContact NH1-O 2.79Å; R285-Y343 VanDerWaalsContact CZ-CE2 3.42Å; R285-Y343 VanDerWaalsContact NH2-CE2 3.31Å
286	M	88.3	Confident	88.2	Confident	61 Å²	61	40 Å²	40	30%	0.3	19%	0.192	S	C	.	.	H	α-helix	trans	-61	-43.2	176.9	-71.1	-54.2	-53.2	0	0	112.3	F282 N283 W284 V289 L290 M335 L339	F282-M286 HydrophobicContact CD1-CG 4Å; F282-M286 HydrophobicContact CD2-CG 4.44Å; F282-M286 HydrophobicContact CE1-CG 3.53Å; F282-M286 HydrophobicContact CE1-SD 4.27Å; F282-M286 HydrophobicContact CE2-CG 4.01Å; F282-M286 HydrophobicContact CE2-SD 3.97Å; F282-M286 HydrophobicContact CG-CG 4.44Å; F282-M286 HydrophobicContact CZ-CG 3.53Å; F282-M286 HydrophobicContact CZ-SD 3.65Å; F282-M286 WeakPolarHBondContact O-CG 3.24Å; F282-M286 PolarHBondContact O-N 2.86Å; N283-M286 PolarHBondContact O-N 3.02Å; W284-M286 PolarHBondContact O-N 2.89Å; M286-V289 WeakPolarHBondContact O-CB 3.43Å; M286-V289 PolarHBondContact O-N 3.31Å; M286-L290 PolarHBondContact O-N 3.46Å; M286-M335 HydrophobicContact CE-CE 3.62Å; M286-M335 HydrophobicContact CE-SD 3.68Å; M286-M335 HydrophobicContact SD-CE 3.43Å; M286-M335 WeakPolarHBondContact SD-CE 3.37Å; M286-M335 HydrophobicContact SD-SD 3.41Å; M286-L339 HydrophobicContact SD-CD1 4.18Å
287	K	84.7	Confident	88.5	Confident	58 Å²	58	36.3 Å²	36.3	25%	0.252	18%	0.175	S	C	.	.	H	α-helix	trans	-60.3	-45.9	175.4	-83.2	-178	175.1	177.3	0	111.5	F204 N208 N283 W284 R285 L290 V291	F204-K287 HydrophobicContact CE1-CB 3.55Å; F204-K287 HydrophobicContact CE1-CD 4.09Å; F204-K287 HydrophobicContact CE1-CG 4.03Å; F204-K287 HydrophobicContact CE2-CD 4.28Å; F204-K287 HydrophobicContact CE2-CG 4.23Å; F204-K287 HydrophobicContact CZ-CB 3.37Å; F204-K287 HydrophobicContact CZ-CD 3.66Å; F204-K287 HydrophobicContact CZ-CG 3.39Å; N208-K287 PolarHBondContact OD1-NZ 3.17Å; N283-K287 VanDerWaalsContact O-CB 3.23Å; N283-K287 WeakPolarHBondContact O-CB 3.18Å; N283-K287 WeakPolarHBondContact O-CG 3.37Å; N283-K287 PolarHBondContact O-N 3.42Å; W284-K287 WeakPolarHBondContact O-CB 3.29Å; W284-K287 PolarHBondContact O-N 3.39Å; R285-K287 VanDerWaalsContact C-N 3.34Å; R285-K287 PolarHBondContact O-N 3Å; K287-L290 PolarHBondContact O-N 2.87Å; K287-V291 VanDerWaalsContact O-CB 3.31Å; K287-V291 WeakPolarHBondContact O-CB 3.37Å; K287-V291 WeakPolarHBondContact O-CG2 3.48Å; K287-V291 PolarHBondContact O-N 3.02Å
288	E	84.4	Confident	88.9	Confident	14 Å²	14	32.3 Å²	32.3	7%	0.065	16%	0.156	C	C	.	.	H	α-helix	trans	-60.6	-44.3	175.5	176.5	58	-151.9	0	0	112.1	H249 W284 R285 V291 S292 L338	H249-E288 IonicContact CE1-OE1 2.9Å; H249-E288 PolarHBondContact CE1-OE1 2.71Å; H249-E288 IonicContact CE1-OE2 3.58Å; H249-E288 PolarHBondContact CE1-OE2 2.86Å; H249-E288 IonicContact NE2-OE2 3.76Å; H249-E288 PolarHBondContact NE2-OE2 3.41Å; W284-E288 PolarHBondContact O-N 2.87Å; R285-E288 WeakPolarHBondContact O-CB 3.49Å; R285-E288 PolarHBondContact O-N 3.42Å; E288-V291 PolarHBondContact O-N 3.47Å; E288-S292 WeakPolarHBondContact O-CB 3.38Å; E288-S292 PolarHBondContact O-N 3.17Å; E288-S292 PolarHBondContact OE1-OG 3.06Å; E288-L338 HydrophobicContact CB-CD1 4.46Å; E288-L338 HydrophobicContact CG-CD1 4.07Å
289	V	90.7	Very high	89.3	Confident	4 Å²	4	32.4 Å²	32.4	2%	0.024	16%	0.157	C	C	.	.	H	α-helix	trans	-56.5	-52.2	175	168.8	0	0	0	0	110.9	R285 M286 V291 S293 L334 M335 L338	R285-V289 VanDerWaalsContact O-CG2 3.31Å; R285-V289 WeakPolarHBondContact O-CG2 3.19Å; R285-V289 PolarHBondContact O-N 2.72Å; M286-V289 WeakPolarHBondContact O-CB 3.43Å; M286-V289 PolarHBondContact O-N 3.31Å; V289-V291 VanDerWaalsContact C-N 3.34Å; V289-V291 PolarHBondContact O-N 2.9Å; V289-S293 VanDerWaalsContact O-CB 3.25Å; V289-S293 WeakPolarHBondContact O-CB 3.31Å; V289-S293 PolarHBondContact O-N 3.46Å; V289-S293 PolarHBondContact O-OG 3.31Å; V289-L334 HydrophobicContact CB-CB 4.49Å; V289-L334 HydrophobicContact CG1-CB 4.23Å; V289-L334 HydrophobicContact CG2-CB 4.05Å; V289-M335 HydrophobicContact CB-CG 4.45Å; V289-M335 HydrophobicContact CB-SD 4.23Å; V289-M335 HydrophobicContact CG1-CG 3.67Å; V289-M335 HydrophobicContact CG1-SD 3.97Å; V289-M335 HydrophobicContact CG2-CG 4.03Å; V289-M335 HydrophobicContact CG2-SD 3.72Å; V289-L338 HydrophobicContact CG2-CB 4.43Å; V289-L338 HydrophobicContact CG2-CD1 3.49Å; V289-L338 VanDerWaalsContact CG2-CD1 3.49Å
290	L	90.3	Very high	89.6	Confident	95 Å²	95	30.9 Å²	30.9	50%	0.497	15%	0.15	S	C	.	.	H	α-helix	trans	-61.3	-46.6	-176.8	179	66.1	0	0	0	111	M286 K287 S293 M294	M286-L290 PolarHBondContact O-N 3.46Å; K287-L290 PolarHBondContact O-N 2.87Å; L290-S293 PolarHBondContact O-OG 3.37Å; L290-M294 HydrophobicContact CD1-CE 4Å; L290-M294 VanDerWaalsContact O-CB 3.3Å; L290-M294 WeakPolarHBondContact O-CB 3.47Å; L290-M294 PolarHBondContact O-N 3.25Å
291	V	88.2	Confident	90.2	Very high	23 Å²	23	28.3 Å²	28.3	14%	0.139	14%	0.138	C	C	.	.	H	α-helix	trans	-70.8	-44.4	-175.7	164.2	0	0	0	0	111	Y201 F204 K287 E288 V289 M294 L295	Y201-V291 HydrophobicContact CD1-CG1 3.63Å; Y201-V291 HydrophobicContact CD2-CG1 3.73Å; Y201-V291 HydrophobicContact CE1-CG1 3.16Å; Y201-V291 HydrophobicContact CE2-CG1 3.29Å; Y201-V291 HydrophobicContact CG-CG1 3.93Å; Y201-V291 VanDerWaalsContact OH-C 3.25Å; Y201-V291 WeakPolarHBondContact OH-CG1 3.45Å; Y201-V291 PolarHBondContact OH-O 3.12Å; Y201-V291 VanDerWaalsContact OH-O 3.07Å; F204-V291 HydrophobicContact CD1-CG2 3.91Å; F204-V291 HydrophobicContact CE1-CB 4.4Å; F204-V291 HydrophobicContact CE1-CG2 3.51Å; F204-V291 HydrophobicContact CE2-CG2 4.26Å; F204-V291 HydrophobicContact CG-CG2 4.37Å; F204-V291 HydrophobicContact CZ-CG2 3.66Å; K287-V291 VanDerWaalsContact O-CB 3.31Å; K287-V291 WeakPolarHBondContact O-CB 3.37Å; K287-V291 WeakPolarHBondContact O-CG2 3.48Å; K287-V291 PolarHBondContact O-N 3.02Å; E288-V291 PolarHBondContact O-N 3.47Å; V289-V291 VanDerWaalsContact C-N 3.34Å; V289-V291 PolarHBondContact O-N 2.9Å; V291-M294 PolarHBondContact O-N 3.04Å; V291-L295 WeakPolarHBondContact O-CB 3.46Å; V291-L295 PolarHBondContact O-N 3.07Å
292	S	89.1	Confident	90.6	Very high	2 Å²	2	30.7 Å²	30.7	1%	0.014	15%	0.148	C	C	.	.	H	α-helix	trans	-66.5	-38.8	176.1	-82.2	0	0	0	0	113.6	Y201 E288 L295 S296	Y201-S292 VanDerWaalsContact OH-CA 3.29Å; Y201-S292 WeakPolarHBondContact OH-CA 3.38Å; Y201-S292 PolarHBondContact OH-N 3.33Å; E288-S292 WeakPolarHBondContact O-CB 3.38Å; E288-S292 PolarHBondContact O-N 3.17Å; E288-S292 PolarHBondContact OE1-OG 3.06Å; S292-L295 PolarHBondContact O-N 2.65Å; S292-S296 PolarHBondContact O-N 2.98Å; S292-S296 PolarHBondContact O-OG 3.01Å; S292-S296 VanDerWaalsContact O-OG 3.1Å
293	S	93.6	Very high	90.8	Very high	0 Å²	0	29.2 Å²	29.2	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-67.4	-39.7	175.1	56.7	0	0	0	0	112.5	V289 L290 S296 A297 S327 S331	V289-S293 VanDerWaalsContact O-CB 3.25Å; V289-S293 WeakPolarHBondContact O-CB 3.31Å; V289-S293 PolarHBondContact O-N 3.46Å; V289-S293 PolarHBondContact O-OG 3.31Å; L290-S293 PolarHBondContact O-OG 3.37Å; S293-S296 PolarHBondContact O-N 3.47Å; S293-A297 PolarHBondContact O-N 3.33Å; S293-S327 WeakPolarHBondContact CB-O 3.21Å; S293-S331 WeakPolarHBondContact CB-OG 3.45Å; S293-S331 PolarHBondContact OG-OG 3.02Å
294	M	92.1	Very high	91.1	Very high	77 Å²	77	25.1 Å²	25.1	38%	0.379	12%	0.119	S	C	.	.	H	α-helix	trans	-67.3	-37.9	176.5	-149.1	63.5	66.7	0	0	111.8	L290 V291 A297 Y298 F323	L290-M294 HydrophobicContact CD1-CE 4Å; L290-M294 VanDerWaalsContact O-CB 3.3Å; L290-M294 WeakPolarHBondContact O-CB 3.47Å; L290-M294 PolarHBondContact O-N 3.25Å; V291-M294 PolarHBondContact O-N 3.04Å; M294-A297 PolarHBondContact O-N 3.46Å; M294-Y298 VanDerWaalsContact O-CB 3.29Å; M294-Y298 WeakPolarHBondContact O-CB 3.35Å; M294-Y298 PolarHBondContact O-N 3.12Å; M294-F323 HydrophobicContact SD-CE1 4.03Å; M294-F323 HydrophobicContact SD-CZ 3.73Å
295	L	92.1	Very high	91.6	Very high	9 Å²	9	24.5 Å²	24.5	5%	0.047	12%	0.119	C	C	.	.	H	α-helix	trans	-59.2	-47.4	172.1	-172	71.8	0	0	0	111.4	R136 P197 Y201 V291 S292 Y298 Y299	R136-L295 VanDerWaalsContact NH2-CD2 3.31Å; P197-L295 HydrophobicContact CB-CD1 3.19Å; P197-L295 HydrophobicContact CG-CD1 3.91Å; Y201-L295 HydrophobicContact CE2-CB 3.96Å; Y201-L295 HydrophobicContact CE2-CD1 3.75Å; Y201-L295 HydrophobicContact CE2-CD2 4.08Å; Y201-L295 HydrophobicContact CE2-CG 4.14Å; Y201-L295 WeakPolarHBondContact OH-CB 3.48Å; Y201-L295 WeakPolarHBondContact OH-CD2 3.33Å; V291-L295 WeakPolarHBondContact O-CB 3.46Å; V291-L295 PolarHBondContact O-N 3.07Å; S292-L295 PolarHBondContact O-N 2.65Å; L295-Y298 WeakPolarHBondContact O-CB 3.31Å; L295-Y298 PolarHBondContact O-N 2.98Å; L295-Y299 HydrophobicContact CD1-CD2 3.9Å; L295-Y299 HydrophobicContact CD1-CE2 3.43Å; L295-Y299 VanDerWaalsContact CD1-CE2 3.43Å; L295-Y299 HydrophobicContact CG-CD2 3.94Å; L295-Y299 HydrophobicContact CG-CE2 3.91Å; L295-Y299 VanDerWaalsContact O-CD2 3.29Å; L295-Y299 WeakPolarHBondContact O-CD2 3.26Å; L295-Y299 PolarHBondContact O-N 3.29Å
296	S	93.5	Very high	91.8	Very high	9 Å²	9	27.4 Å²	27.4	6%	0.063	13%	0.13	C	C	.	.	H	α-helix	trans	-61.9	-46.1	178.3	-63.5	0	0	0	0	111.6	Q88 S292 S293 Y298 Y299 V300	Q88-S296 PolarHBondContact NE2-OG 3.36Å; S292-S296 PolarHBondContact O-N 2.98Å; S292-S296 PolarHBondContact O-OG 3.01Å; S292-S296 VanDerWaalsContact O-OG 3.1Å; S293-S296 PolarHBondContact O-N 3.47Å; S296-Y298 VanDerWaalsContact C-N 3.31Å; S296-Y298 PolarHBondContact O-N 3.36Å; S296-Y299 PolarHBondContact O-N 3.2Å; S296-V300 VanDerWaalsContact O-CB 3.26Å; S296-V300 WeakPolarHBondContact O-CB 3Å; S296-V300 VanDerWaalsContact O-CG2 3.22Å; S296-V300 WeakPolarHBondContact O-CG2 3.29Å; S296-V300 PolarHBondContact O-N 3.18Å
297	A	95.2	Very high	91.9	Very high	0 Å²	0	25.1 Å²	25.1	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-62.1	-39.2	176.5	0	0	0	0	0	112.1	S293 M294 A301 F323 V326	S293-A297 PolarHBondContact O-N 3.33Å; M294-A297 PolarHBondContact O-N 3.46Å; A297-A301 WeakPolarHBondContact O-CB 3.07Å; A297-A301 PolarHBondContact O-N 2.91Å; A297-F323 HydrophobicContact CB-CD2 3.79Å; A297-F323 HydrophobicContact CB-CE1 4.43Å; A297-F323 HydrophobicContact CB-CE2 3.67Å; A297-F323 HydrophobicContact CB-CG 4.23Å; A297-F323 HydrophobicContact CB-CZ 4.01Å; A297-V326 HydrophobicContact CB-CG1 4.29Å
298	Y	94.7	Very high	92.2	Very high	28 Å²	28	22.9 Å²	22.9	11%	0.11	11%	0.11	C	C	.	.	I	π-helix	trans	-59.6	-52.1	175.8	-175.5	-91.5	0	0	0	111.9	F193 P197 M294 L295 S296 F302 V303	F193-Y298 WeakPolarHBondContact O-CE1 3.48Å; F193-Y298 PolarHBondContact O-OH 3.48Å; P197-Y298 HydrophobicContact CG-CD1 3.25Å; P197-Y298 HydrophobicContact CG-CD2 4.21Å; P197-Y298 HydrophobicContact CG-CE1 3.4Å; P197-Y298 VanDerWaalsContact CG-CE1 3.4Å; P197-Y298 HydrophobicContact CG-CE2 4.33Å; P197-Y298 HydrophobicContact CG-CG 3.69Å; M294-Y298 VanDerWaalsContact O-CB 3.29Å; M294-Y298 WeakPolarHBondContact O-CB 3.35Å; M294-Y298 PolarHBondContact O-N 3.12Å; L295-Y298 WeakPolarHBondContact O-CB 3.31Å; L295-Y298 PolarHBondContact O-N 2.98Å; S296-Y298 VanDerWaalsContact C-N 3.31Å; S296-Y298 PolarHBondContact O-N 3.36Å; Y298-F302 HydrophobicContact CD2-CB 4.09Å; Y298-F302 AromaticContact CD2-CD1 3.81Å; Y298-F302 HydrophobicContact CD2-CD1 3.81Å; Y298-F302 HydrophobicContact CD2-CG 4.09Å; Y298-F302 HydrophobicContact CE1-CD1 4.19Å; Y298-F302 HydrophobicContact CE2-CB 4.36Å; Y298-F302 AromaticContact CE2-CD1 3.21Å; Y298-F302 HydrophobicContact CE2-CD1 3.21Å; Y298-F302 AromaticContact CE2-CE1 3.57Å; Y298-F302 HydrophobicContact CE2-CE1 3.57Å; Y298-F302 AromaticContact CE2-CG 3.88Å; Y298-F302 HydrophobicContact CE2-CG 3.88Å; Y298-F302 HydrophobicContact CE2-CZ 4.46Å; Y298-F302 HydrophobicContact CG-CB 4.48Å; Y298-F302 HydrophobicContact CG-CD1 4.5Å; Y298-F302 AromaticContact CZ-CD1 3.42Å; Y298-F302 VanDerWaalsContact CZ-CD1 3.42Å; Y298-F302 AromaticContact CZ-CE1 3.67Å; Y298-F302 WeakPolarHBondContact O-CA 2.98Å; Y298-F302 VanDerWaalsContact O-CB 3.29Å; Y298-F302 WeakPolarHBondContact O-CB 3.49Å; Y298-F302 PolarHBondContact O-N 3.49Å; Y298-F302 VanDerWaalsContact OH-CE1 3.31Å; Y298-F302 WeakPolarHBondContact OH-CE1 3.35Å; Y298-V303 HydrophobicContact CD1-CG2 3.66Å; Y298-V303 HydrophobicContact CE1-CG2 3.39Å; Y298-V303 PolarHBondContact O-N 2.95Å
299	Y	95	Very high	92.3	Very high	2 Å²	2	29.3 Å²	29.3	1%	0.008	14%	0.138	C	C	.	.	I	π-helix	trans	-72.6	-31.6	-179.2	-80.2	-70.6	0	0	0	113.8	T130 V133 L194 P197 F198 L295 S296 V303 P304	T130-Y299 HydrophobicContact CG2-CD1 4.27Å; T130-Y299 WeakPolarHBondContact CG2-O 3.36Å; V133-Y299 HydrophobicContact CB-CE1 4.35Å; V133-Y299 HydrophobicContact CB-CE2 4.42Å; V133-Y299 HydrophobicContact CG1-CD1 4.33Å; V133-Y299 HydrophobicContact CG1-CD2 3.71Å; V133-Y299 HydrophobicContact CG1-CE1 4.03Å; V133-Y299 HydrophobicContact CG1-CE2 3.31Å; V133-Y299 HydrophobicContact CG1-CG 4.21Å; V133-Y299 HydrophobicContact CG2-CE1 4.47Å; L194-Y299 HydrophobicContact CD2-CE1 4.43Å; L194-Y299 PolarHBondContact O-OH 2.79Å; P197-Y299 HydrophobicContact CG-CE2 4.33Å; F198-Y299 HydrophobicContact CE2-CE2 4.49Å; F198-Y299 WeakPolarHBondContact CE2-OH 3.2Å; L295-Y299 HydrophobicContact CD1-CD2 3.9Å; L295-Y299 HydrophobicContact CD1-CE2 3.43Å; L295-Y299 VanDerWaalsContact CD1-CE2 3.43Å; L295-Y299 HydrophobicContact CG-CD2 3.94Å; L295-Y299 HydrophobicContact CG-CE2 3.91Å; L295-Y299 VanDerWaalsContact O-CD2 3.29Å; L295-Y299 WeakPolarHBondContact O-CD2 3.26Å; L295-Y299 PolarHBondContact O-N 3.29Å; S296-Y299 PolarHBondContact O-N 3.2Å; Y299-V303 HydrophobicContact CD1-CB 4.37Å; Y299-V303 HydrophobicContact CD1-CG2 3.73Å; Y299-V303 HydrophobicContact CE1-CG2 4.1Å; Y299-V303 HydrophobicContact CG-CG2 4.42Å; Y299-P304 WeakPolarHBondContact O-CD 3.37Å
300	V	95.8	Very high	91.9	Very high	0 Å²	0	37.4 Å²	37.4	0%	0	18%	0.181	C	C	.	.	I	π-helix	trans	-78.3	-42.4	-179.1	170.7	0	0	0	0	112.2	A91 H95 L134 S296 V326	A91-V300 HydrophobicContact CB-CG1 3.7Å; H95-V300 PolarHBondContact CD2-O 3.37Å; L134-V300 HydrophobicContact CD1-CG2 3.77Å; L134-V300 HydrophobicContact CD2-CG2 4.12Å; S296-V300 VanDerWaalsContact O-CB 3.26Å; S296-V300 WeakPolarHBondContact O-CB 3Å; S296-V300 VanDerWaalsContact O-CG2 3.22Å; S296-V300 WeakPolarHBondContact O-CG2 3.29Å; S296-V300 PolarHBondContact O-N 3.18Å; V300-V326 HydrophobicContact CB-CG1 4.27Å; V300-V326 HydrophobicContact CG1-CG1 4.42Å; V300-V326 HydrophobicContact CG1-CG2 3.97Å; V300-V326 HydrophobicContact CG2-CG1 4.45Å
301	A	94.1	Very high	91.6	Very high	3 Å²	3	39.2 Å²	39.2	3%	0.025	20%	0.196	C	C	.	.	I	π-helix	trans	-113	-34.5	-170.3	0	0	0	0	0	114.4	H95 A297 L322 F323	H95-A301 PolarHBondContact NE2-O 3.17Å; A297-A301 WeakPolarHBondContact O-CB 3.07Å; A297-A301 PolarHBondContact O-N 2.91Å; A301-L322 HydrophobicContact CB-CG 4.47Å; A301-F323 HydrophobicContact CB-CB 3.84Å; A301-F323 HydrophobicContact CB-CD2 4.19Å
302	F	93.8	Very high	91.4	Very high	67 Å²	67	40.4 Å²	40.4	29%	0.294	20%	0.2	S	C	.	.	I	π-helix	trans	-85.6	-48.6	-177.8	178.2	-90.6	0	0	0	112.3	F193 Y298 V305 W306	F193-F302 HydrophobicContact CD1-CE1 4.37Å; Y298-F302 HydrophobicContact CD2-CB 4.09Å; Y298-F302 AromaticContact CD2-CD1 3.81Å; Y298-F302 HydrophobicContact CD2-CD1 3.81Å; Y298-F302 HydrophobicContact CD2-CG 4.09Å; Y298-F302 HydrophobicContact CE1-CD1 4.19Å; Y298-F302 HydrophobicContact CE2-CB 4.36Å; Y298-F302 AromaticContact CE2-CD1 3.21Å; Y298-F302 HydrophobicContact CE2-CD1 3.21Å; Y298-F302 AromaticContact CE2-CE1 3.57Å; Y298-F302 HydrophobicContact CE2-CE1 3.57Å; Y298-F302 AromaticContact CE2-CG 3.88Å; Y298-F302 HydrophobicContact CE2-CG 3.88Å; Y298-F302 HydrophobicContact CE2-CZ 4.46Å; Y298-F302 HydrophobicContact CG-CB 4.48Å; Y298-F302 HydrophobicContact CG-CD1 4.5Å; Y298-F302 AromaticContact CZ-CD1 3.42Å; Y298-F302 VanDerWaalsContact CZ-CD1 3.42Å; Y298-F302 AromaticContact CZ-CE1 3.67Å; Y298-F302 WeakPolarHBondContact O-CA 2.98Å; Y298-F302 VanDerWaalsContact O-CB 3.29Å; Y298-F302 WeakPolarHBondContact O-CB 3.49Å; Y298-F302 PolarHBondContact O-N 3.49Å; Y298-F302 VanDerWaalsContact OH-CE1 3.31Å; Y298-F302 WeakPolarHBondContact OH-CE1 3.35Å; F302-V305 PolarHBondContact O-N 3.39Å; F302-W306 HydrophobicContact CD1-CB 4.43Å; F302-W306 HydrophobicContact CE1-CB 4.07Å; F302-W306 HydrophobicContact CE1-CD2 4.09Å; F302-W306 AromaticContact CE1-CE3 3.9Å; F302-W306 HydrophobicContact CE1-CE3 3.9Å; F302-W306 HydrophobicContact CE1-CG 4.16Å; F302-W306 AromaticContact CE2-CE3 3.97Å; F302-W306 HydrophobicContact CE2-CE3 3.97Å; F302-W306 HydrophobicContact CE2-CZ3 4.46Å; F302-W306 HydrophobicContact CZ-CB 4.45Å; F302-W306 AromaticContact CZ-CD2 3.93Å; F302-W306 HydrophobicContact CZ-CD2 3.93Å; F302-W306 AromaticContact CZ-CE3 3.27Å; F302-W306 HydrophobicContact CZ-CE3 3.27Å; F302-W306 HydrophobicContact CZ-CG 4.42Å; F302-W306 AromaticContact CZ-CZ3 3.82Å; F302-W306 HydrophobicContact CZ-CZ3 3.82Å; F302-W306 WeakPolarHBondContact O-CB 3.2Å; F302-W306 PolarHBondContact O-N 2.75Å
303	V	93.8	Very high	91.1	Very high	2 Å²	2	50 Å²	50	1%	0.012	24%	0.237	C	C	.	.	H	α-helix	trans	-58.4	-49	-175.2	168.1	0	0	0	0	112.5	L126 L194 Y298 Y299 V305 W306 F307	L126-V303 HydrophobicContact CD1-CG1 3.96Å; L194-V303 HydrophobicContact CD2-CG1 3.54Å; L194-V303 HydrophobicContact CD2-CG2 4.22Å; Y298-V303 HydrophobicContact CD1-CG2 3.66Å; Y298-V303 HydrophobicContact CE1-CG2 3.39Å; Y298-V303 PolarHBondContact O-N 2.95Å; Y299-V303 HydrophobicContact CD1-CB 4.37Å; Y299-V303 HydrophobicContact CD1-CG2 3.73Å; Y299-V303 HydrophobicContact CE1-CG2 4.1Å; Y299-V303 HydrophobicContact CG-CG2 4.42Å; V303-V305 VanDerWaalsContact C-N 3.31Å; V303-V305 PolarHBondContact O-N 3.36Å; V303-W306 PolarHBondContact O-N 3.4Å; V303-F307 HydrophobicContact CG1-CD2 4.16Å; V303-F307 HydrophobicContact CG1-CE2 4.31Å; V303-F307 WeakPolarHBondContact O-CD2 3.41Å; V303-F307 PolarHBondContact O-N 3.27Å
304	P	93.6	Very high	90.8	Very high	0 Å²	0	52.7 Å²	52.7	0%	0	25%	0.248	C	C	.	.	H	α-helix	trans	-60.3	-43	-179.5	-27.5	39.8	0	0	0	111.7	L92 Y96 I99 Y299 W306 F307 V308	L92-P304 HydrophobicContact CD1-CG 4.03Å; Y96-P304 HydrophobicContact CD2-CB 4.47Å; Y96-P304 HydrophobicContact CD2-CG 4.48Å; Y96-P304 HydrophobicContact CE2-CB 3.86Å; Y96-P304 HydrophobicContact CE2-CG 3.72Å; I99-P304 HydrophobicContact CD1-CB 3.74Å; Y299-P304 WeakPolarHBondContact O-CD 3.37Å; P304-W306 PolarHBondContact O-N 2.95Å; P304-F307 PolarHBondContact O-N 2.74Å; P304-V308 VanDerWaalsContact O-CG2 3.28Å; P304-V308 WeakPolarHBondContact O-CG2 3.27Å; P304-V308 PolarHBondContact O-N 3.11Å
305	V	92.9	Very high	90.6	Very high	21 Å²	21	51.1 Å²	51.1	13%	0.127	24%	0.241	C	C	.	.	H	α-helix	trans	-63.1	-39	177	165.9	0	0	0	0	112.7	H95 I99 F302 V303 F307 V308 Y314	H95-V305 WeakPolarHBondContact NE2-CG2 3.41Å; I99-V305 HydrophobicContact CD1-CG2 4.07Å; F302-V305 PolarHBondContact O-N 3.39Å; V303-V305 VanDerWaalsContact C-N 3.31Å; V303-V305 PolarHBondContact O-N 3.36Å; V305-F307 VanDerWaalsContact C-N 3.31Å; V305-F307 PolarHBondContact O-N 3.01Å; V305-V308 WeakPolarHBondContact O-CB 3.03Å; V305-V308 PolarHBondContact O-N 3.31Å; V305-Y314 HydrophobicContact CB-CE2 4.4Å; V305-Y314 HydrophobicContact CG1-CD2 4.36Å; V305-Y314 HydrophobicContact CG1-CE1 4.14Å; V305-Y314 HydrophobicContact CG1-CE2 3.46Å; V305-Y314 VanDerWaalsContact CG1-CE2 3.46Å; V305-Y314 WeakPolarHBondContact CG1-OH 3.35Å; V305-Y314 HydrophobicContact CG2-CD2 4.22Å; V305-Y314 HydrophobicContact CG2-CE2 4.02Å
306	W	91.7	Very high	90.5	Very high	100 Å²	100	58.1 Å²	58.1	38%	0.379	27%	0.271	S	S	.	.	H	α-helix	trans	-63.9	-35.4	-178.4	-174.5	-92.7	0	0	0	113.1	F193 F302 V303 P304	F193-W306 HydrophobicContact CD1-CH2 4.35Å; F193-W306 HydrophobicContact CD1-CZ2 4.09Å; F193-W306 AromaticContact CD2-CE2 3.61Å; F193-W306 HydrophobicContact CD2-CH2 4.42Å; F193-W306 AromaticContact CD2-CZ2 3.49Å; F193-W306 HydrophobicContact CD2-CZ2 3.49Å; F193-W306 VanDerWaalsContact CD2-CZ2 3.49Å; F193-W306 AromaticContact CD2-NE1 3.57Å; F193-W306 AromaticContact CE1-CH2 3.79Å; F193-W306 HydrophobicContact CE1-CH2 3.79Å; F193-W306 AromaticContact CE1-CZ2 3.82Å; F193-W306 HydrophobicContact CE1-CZ2 3.82Å; F193-W306 HydrophobicContact CE1-CZ3 4.35Å; F193-W306 AromaticContact CE2-CE2 3.84Å; F193-W306 AromaticContact CE2-CH2 3.89Å; F193-W306 HydrophobicContact CE2-CH2 3.89Å; F193-W306 AromaticContact CE2-CZ2 3.2Å; F193-W306 HydrophobicContact CE2-CZ2 3.2Å; F193-W306 HydrophobicContact CG-CD2 4.42Å; F193-W306 AromaticContact CG-CE2 3.79Å; F193-W306 AromaticContact CG-CZ2 3.94Å; F193-W306 HydrophobicContact CG-CZ2 3.94Å; F193-W306 AromaticContact CG-NE1 3.83Å; F193-W306 AromaticContact CZ-CH2 3.54Å; F193-W306 HydrophobicContact CZ-CH2 3.54Å; F193-W306 AromaticContact CZ-CZ2 3.37Å; F193-W306 HydrophobicContact CZ-CZ2 3.37Å; F302-W306 HydrophobicContact CD1-CB 4.43Å; F302-W306 HydrophobicContact CE1-CB 4.07Å; F302-W306 HydrophobicContact CE1-CD2 4.09Å; F302-W306 AromaticContact CE1-CE3 3.9Å; F302-W306 HydrophobicContact CE1-CE3 3.9Å; F302-W306 HydrophobicContact CE1-CG 4.16Å; F302-W306 AromaticContact CE2-CE3 3.97Å; F302-W306 HydrophobicContact CE2-CE3 3.97Å; F302-W306 HydrophobicContact CE2-CZ3 4.46Å; F302-W306 HydrophobicContact CZ-CB 4.45Å; F302-W306 AromaticContact CZ-CD2 3.93Å; F302-W306 HydrophobicContact CZ-CD2 3.93Å; F302-W306 AromaticContact CZ-CE3 3.27Å; F302-W306 HydrophobicContact CZ-CE3 3.27Å; F302-W306 HydrophobicContact CZ-CG 4.42Å; F302-W306 AromaticContact CZ-CZ3 3.82Å; F302-W306 HydrophobicContact CZ-CZ3 3.82Å; F302-W306 WeakPolarHBondContact O-CB 3.2Å; F302-W306 PolarHBondContact O-N 2.75Å; V303-W306 PolarHBondContact O-N 3.4Å; P304-W306 PolarHBondContact O-N 2.95Å
307	F	91.6	Very high	90.4	Very high	14 Å²	14	66 Å²	66	6%	0.061	30%	0.3	C	S	.	.	T	Hydrogen-bonded Turn	trans	-92.8	-0.8	-178.9	-76	-89.8	0	0	0	113.7	L126 Y186 N190 L191 L194 V303 P304 V305	L126-F307 HydrophobicContact CD1-CD1 4.41Å; L126-F307 HydrophobicContact CD1-CD2 3.75Å; L126-F307 HydrophobicContact CD1-CE2 3.94Å; L126-F307 HydrophobicContact CD1-CG 4.02Å; L126-F307 HydrophobicContact CD1-CZ 4.36Å; L126-F307 HydrophobicContact CD2-CB 3.34Å; L126-F307 HydrophobicContact CD2-CD1 4.42Å; L126-F307 HydrophobicContact CD2-CD2 3.89Å; L126-F307 HydrophobicContact CD2-CG 3.64Å; L126-F307 HydrophobicContact CG-CD2 4.49Å; L126-F307 HydrophobicContact CG-CG 4.48Å; Y186-F307 AromaticContact CD1-CD1 3.87Å; Y186-F307 HydrophobicContact CD1-CD1 3.87Å; Y186-F307 HydrophobicContact CD1-CE1 4.16Å; Y186-F307 HydrophobicContact CD2-CD1 4.02Å; Y186-F307 AromaticContact CD2-CE1 3.94Å; Y186-F307 HydrophobicContact CD2-CE1 3.94Å; Y186-F307 AromaticContact CE1-CD1 3.78Å; Y186-F307 HydrophobicContact CE1-CD1 3.78Å; Y186-F307 HydrophobicContact CE1-CE1 4.49Å; Y186-F307 AromaticContact CE2-CD1 3.95Å; Y186-F307 HydrophobicContact CE2-CD1 3.95Å; Y186-F307 HydrophobicContact CE2-CE1 4.3Å; Y186-F307 AromaticContact CG-CD1 3.99Å; Y186-F307 HydrophobicContact CG-CD1 3.99Å; Y186-F307 AromaticContact CG-CE1 3.87Å; Y186-F307 HydrophobicContact CG-CE1 3.87Å; Y186-F307 AromaticContact CZ-CD1 3.84Å; N190-F307 HydrophobicContact CB-CE1 4.32Å; N190-F307 WeakPolarHBondContact O-CZ 3.25Å; L191-F307 HydrophobicContact CD2-CE1 4.14Å; L191-F307 HydrophobicContact CD2-CZ 4.23Å; L194-F307 HydrophobicContact CD1-CE2 4.14Å; L194-F307 HydrophobicContact CD1-CZ 3.74Å; L194-F307 HydrophobicContact CD2-CE2 3.71Å; L194-F307 HydrophobicContact CD2-CZ 4.19Å; L194-F307 HydrophobicContact CG-CE2 3.71Å; L194-F307 HydrophobicContact CG-CZ 3.7Å; V303-F307 HydrophobicContact CG1-CD2 4.16Å; V303-F307 HydrophobicContact CG1-CE2 4.31Å; V303-F307 WeakPolarHBondContact O-CD2 3.41Å; V303-F307 PolarHBondContact O-N 3.27Å; P304-F307 PolarHBondContact O-N 2.74Å; V305-F307 VanDerWaalsContact C-N 3.31Å; V305-F307 PolarHBondContact O-N 3.01Å
308	V	89.9	Confident	90.1	Very high	10 Å²	10	67.1 Å²	67.1	6%	0.061	30%	0.304	C	S	.	.	S	Bend	trans	-64.3	136.8	171.3	167.3	0	0	0	0	109.4	I99 P304 V305 N310 H312 Y314	I99-V308 HydrophobicContact CD1-CG2 4.34Å; I99-V308 HydrophobicContact CG2-CG2 3.45Å; I99-V308 VanDerWaalsContact CG2-CG2 3.45Å; P304-V308 VanDerWaalsContact O-CG2 3.28Å; P304-V308 WeakPolarHBondContact O-CG2 3.27Å; P304-V308 PolarHBondContact O-N 3.11Å; V305-V308 WeakPolarHBondContact O-CB 3.03Å; V305-V308 PolarHBondContact O-N 3.31Å; V308-N310 PolarHBondContact O-N 3.05Å; V308-H312 HydrophobicContact CG1-CB 3.67Å; V308-Y314 HydrophobicContact CG1-CD1 4.2Å
309	K	86.3	Confident	90	Very high	150 Å²	150	66.5 Å²	66.5	65%	0.652	30%	0.304	S	S	*	.			trans	-58.7	137.5	175.8	-66.8	179.9	179.9	177.5	0	110	T311 H312	K309-T311 PolarHBondContact O-N 2.7Å; K309-H312 WeakPolarHBondContact O-CB 3.38Å; K309-H312 PolarHBondContact O-N 2.92Å
310	N	82.5	Confident	89.9	Confident	173 Å²	173	70 Å²	70	93%	0.925	33%	0.327	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.8	-20.8	-179.5	-67.4	-26.9	0	0	0	114.4	V308 H312	V308-N310 PolarHBondContact O-N 3.05Å; N310-H312 VanDerWaalsContact C-N 3.33Å
311	T	83.9	Confident	89.8	Confident	134 Å²	134	71.9 Å²	71.9	82%	0.822	34%	0.336	S	S	*	.	T	Hydrogen-bonded Turn	trans	-79.6	-13.9	177.6	55.4	0	0	0	0	113.7	K309	K309-T311 PolarHBondContact O-N 2.7Å
312	H	84.6	Confident	89.8	Confident	47 Å²	47	72 Å²	72	22%	0.218	34%	0.336	C	S	.	.	S	Bend	trans	-92.4	121.9	-174.6	-167.3	79.2	0	0	0	110.8	I99 V308 K309 N310	I99-H312 PolarHBondContact O-NE2 3.47Å; V308-H312 HydrophobicContact CG1-CB 3.67Å; K309-H312 WeakPolarHBondContact O-CB 3.38Å; K309-H312 PolarHBondContact O-N 2.92Å; N310-H312 VanDerWaalsContact C-N 3.33Å
313	Y	83.4	Confident	89.8	Confident	203 Å²	203	71.5 Å²	71.5	80%	0.796	33%	0.334	S	S	*	.			trans	-80.4	125.7	178.4	-178.9	-92.8	0	0	0	110.8
314	Y	86	Confident	89.8	Confident	58 Å²	58	75.9 Å²	75.9	23%	0.227	36%	0.357	C	S	.	.			trans	-134.5	158.5	173	68.8	-87.7	0	0	0	110.8	V305 V308 K316	V305-Y314 HydrophobicContact CB-CE2 4.4Å; V305-Y314 HydrophobicContact CG1-CD2 4.36Å; V305-Y314 HydrophobicContact CG1-CE1 4.14Å; V305-Y314 HydrophobicContact CG1-CE2 3.46Å; V305-Y314 VanDerWaalsContact CG1-CE2 3.46Å; V305-Y314 WeakPolarHBondContact CG1-OH 3.35Å; V305-Y314 HydrophobicContact CG2-CD2 4.22Å; V305-Y314 HydrophobicContact CG2-CE2 4.02Å; V308-Y314 HydrophobicContact CG1-CD1 4.2Å; Y314-K316 HydrophobicContact CD2-CG 4.42Å; Y314-K316 HydrophobicContact CE2-CG 3.71Å; Y314-K316 PolarHBondContact O-N 3.44Å
315	D	88.6	Confident	89.9	Confident	44 Å²	44	76.7 Å²	76.7	24%	0.235	36%	0.361	C	S	.	.			trans	-81.8	107.1	179.7	-167.9	-25.8	0	0	0	110.8	R317 W318 S319	D315-R317 WeakPolarHBondContact OD1-CB 3.48Å; D315-R317 PolarHBondContact OD1-N 3.27Å; D315-W318 HydrophobicContact CB-CB 3.95Å; D315-W318 PolarHBondContact OD1-N 2.97Å; D315-S319 PolarHBondContact O-N 3.16Å; D315-S319 PolarHBondContact O-OG 2.95Å
316	K	89.1	Confident	89.9	Confident	155 Å²	155	76.1 Å²	76.1	67%	0.674	36%	0.358	S	S	*	.	H	α-helix	trans	-65.9	-37	178.6	-66.6	-179	-178.2	177.1	0	112.3	Y314 S319 C320	Y314-K316 HydrophobicContact CD2-CG 4.42Å; Y314-K316 HydrophobicContact CE2-CG 3.71Å; Y314-K316 PolarHBondContact O-N 3.44Å; K316-S319 PolarHBondContact O-N 3.12Å; K316-C320 PolarHBondContact O-N 3.49Å; K316-C320 VanDerWaalsContact O-N 3.07Å
317	R	91.1	Very high	90.1	Very high	176 Å²	176	72.1 Å²	72.1	66%	0.664	35%	0.345	S	S	*	.	H	α-helix	trans	-62.7	-47.8	-179.9	178.3	-175.1	169.5	111.6	10.5	109.5	D315 S319 C320 E321	D315-R317 WeakPolarHBondContact OD1-CB 3.48Å; D315-R317 PolarHBondContact OD1-N 3.27Å; R317-S319 VanDerWaalsContact C-N 3.3Å; R317-S319 PolarHBondContact O-N 3.5Å; R317-C320 WeakPolarHBondContact O-CB 3.48Å; R317-C320 PolarHBondContact O-N 3.06Å; R317-C320 VanDerWaalsContact O-N 3.15Å; R317-E321 IonicContact CZ-OE1 3.2Å; R317-E321 IonicContact NE-OE1 2.75Å; R317-E321 PolarHBondContact NE-OE1 3.37Å; R317-E321 IonicContact NH2-OE1 2.85Å; R317-E321 PolarHBondContact NH2-OE1 3.43Å; R317-E321 WeakPolarHBondContact O-CG 3.18Å; R317-E321 PolarHBondContact O-N 3.38Å
318	W	89.9	Confident	90.3	Very high	22 Å²	22	74 Å²	74	8%	0.083	36%	0.355	C	S	.	.	H	α-helix	trans	-60.3	-40.9	178.6	-171.8	-101.4	0	0	0	112.9	N98 D315 C320 E321 L322 Q448 L452	N98-W318 PolarHBondContact ND2-NE1 2.87Å; D315-W318 HydrophobicContact CB-CB 3.95Å; D315-W318 PolarHBondContact OD1-N 2.97Å; W318-C320 VanDerWaalsContact C-N 3.29Å; W318-C320 PolarHBondContact O-N 3.27Å; W318-E321 PolarHBondContact O-N 3.03Å; W318-L322 WeakPolarHBondContact O-CB 3.45Å; W318-L322 PolarHBondContact O-N 3.32Å; W318-Q448 HydrophobicContact CD2-CG 4.28Å; W318-Q448 HydrophobicContact CE3-CG 4.03Å; W318-Q448 HydrophobicContact CH2-CB 3.65Å; W318-Q448 HydrophobicContact CH2-CG 3.8Å; W318-Q448 HydrophobicContact CZ2-CB 4.19Å; W318-Q448 HydrophobicContact CZ2-CG 4.15Å; W318-Q448 HydrophobicContact CZ3-CB 3.99Å; W318-Q448 HydrophobicContact CZ3-CG 3.77Å; W318-L452 HydrophobicContact CH2-CD1 3.74Å; W318-L452 HydrophobicContact CH2-CD2 4.06Å; W318-L452 HydrophobicContact CH2-CG 3.62Å; W318-L452 HydrophobicContact CZ2-CG 4.29Å; W318-L452 HydrophobicContact CZ3-CD1 4.34Å
319	S	92.4	Very high	90.4	Very high	16 Å²	16	73.9 Å²	73.9	11%	0.112	36%	0.355	C	S	.	.	H	α-helix	trans	-63.7	-37.2	177.9	-54.2	0	0	0	0	111.6	D315 K316 R317 F323	D315-S319 PolarHBondContact O-N 3.16Å; D315-S319 PolarHBondContact O-OG 2.95Å; K316-S319 PolarHBondContact O-N 3.12Å; R317-S319 VanDerWaalsContact C-N 3.3Å; R317-S319 PolarHBondContact O-N 3.5Å; S319-F323 WeakPolarHBondContact O-CB 3.43Å; S319-F323 PolarHBondContact O-N 3.42Å
320	C	93.5	Very high	90.8	Very high	75 Å²	75	67.1 Å²	67.1	51%	0.507	33%	0.326	S	S	.	.	H	α-helix	trans	-69.6	-44.5	174.5	-173.2	0	0	0	0	112.3	K316 R317 W318 L322 F323 L324	K316-C320 PolarHBondContact O-N 3.49Å; K316-C320 VanDerWaalsContact O-N 3.07Å; R317-C320 WeakPolarHBondContact O-CB 3.48Å; R317-C320 PolarHBondContact O-N 3.06Å; R317-C320 VanDerWaalsContact O-N 3.15Å; W318-C320 VanDerWaalsContact C-N 3.29Å; W318-C320 PolarHBondContact O-N 3.27Å; C320-L322 VanDerWaalsContact C-N 3.33Å; C320-L322 PolarHBondContact O-N 3.25Å; C320-F323 WeakPolarHBondContact O-CB 3.36Å; C320-F323 PolarHBondContact O-N 3.48Å; C320-L324 WeakPolarHBondContact O-CG 3.15Å; C320-L324 PolarHBondContact O-N 3.46Å
321	E	93	Very high	91.4	Very high	39 Å²	39	60 Å²	60	18%	0.182	29%	0.29	C	S	.	.	H	α-helix	trans	-60.4	-43.4	175.5	-71.4	-178.5	-172.6	0	0	111.3	R317 W318 L324 L325 Y435	R317-E321 IonicContact CZ-OE1 3.2Å; R317-E321 IonicContact NE-OE1 2.75Å; R317-E321 PolarHBondContact NE-OE1 3.37Å; R317-E321 IonicContact NH2-OE1 2.85Å; R317-E321 PolarHBondContact NH2-OE1 3.43Å; R317-E321 WeakPolarHBondContact O-CG 3.18Å; R317-E321 PolarHBondContact O-N 3.38Å; W318-E321 PolarHBondContact O-N 3.03Å; E321-L324 PolarHBondContact O-N 3.42Å; E321-L325 VanDerWaalsContact O-CB 3.26Å; E321-L325 WeakPolarHBondContact O-CB 3.33Å; E321-L325 PolarHBondContact O-N 3.39Å; E321-Y435 PolarHBondContact OE1-OH 3.19Å; E321-Y435 PolarHBondContact OE2-OH 2.84Å
322	L	93.5	Very high	91.9	Very high	5 Å²	5	53.7 Å²	53.7	3%	0.026	25%	0.251	C	S	.	.	H	α-helix	trans	-63.7	-41.1	175.4	-176.2	65.4	0	0	0	112.1	H95 A301 W318 C320 L324 L325 V326 I455	H95-L322 HydrophobicContact CB-CD2 3.53Å; H95-L322 VanDerWaalsContact ND1-CD2 3.32Å; H95-L322 WeakPolarHBondContact ND1-CD2 2.98Å; A301-L322 HydrophobicContact CB-CG 4.47Å; W318-L322 WeakPolarHBondContact O-CB 3.45Å; W318-L322 PolarHBondContact O-N 3.32Å; C320-L322 VanDerWaalsContact C-N 3.33Å; C320-L322 PolarHBondContact O-N 3.25Å; L322-L324 PolarHBondContact O-N 2.9Å; L322-L325 PolarHBondContact O-N 3.31Å; L322-V326 HydrophobicContact CD1-CG2 3.9Å; L322-V326 HydrophobicContact CG-CG2 4.15Å; L322-V326 WeakPolarHBondContact O-CB 3.34Å; L322-V326 VanDerWaalsContact O-CG2 3.27Å; L322-V326 WeakPolarHBondContact O-CG2 3.26Å; L322-V326 PolarHBondContact O-N 3.43Å; L322-I455 HydrophobicContact CD1-CD1 3.36Å
323	F	95.1	Very high	92.2	Very high	57 Å²	57	52.2 Å²	52.2	25%	0.25	25%	0.245	C	C	.	.	H	α-helix	trans	-57.4	-49.2	175.8	179.2	-85	0	0	0	111.3	M294 A297 A301 S319 C320 S327	M294-F323 HydrophobicContact SD-CE1 4.03Å; M294-F323 HydrophobicContact SD-CZ 3.73Å; A297-F323 HydrophobicContact CB-CD2 3.79Å; A297-F323 HydrophobicContact CB-CE1 4.43Å; A297-F323 HydrophobicContact CB-CE2 3.67Å; A297-F323 HydrophobicContact CB-CG 4.23Å; A297-F323 HydrophobicContact CB-CZ 4.01Å; A301-F323 HydrophobicContact CB-CB 3.84Å; A301-F323 HydrophobicContact CB-CD2 4.19Å; S319-F323 WeakPolarHBondContact O-CB 3.43Å; S319-F323 PolarHBondContact O-N 3.42Å; C320-F323 WeakPolarHBondContact O-CB 3.36Å; C320-F323 PolarHBondContact O-N 3.48Å; F323-S327 VanDerWaalsContact O-CB 3.25Å; F323-S327 WeakPolarHBondContact O-CB 3.31Å; F323-S327 PolarHBondContact O-N 2.95Å
324	L	94.1	Very high	92.6	Very high	95 Å²	95	42.6 Å²	42.6	50%	0.497	21%	0.207	S	C	.	.	H	α-helix	trans	-64	-43.7	178	-66.9	177.1	0	0	0	111.4	C320 E321 L322 S327 I328	C320-L324 WeakPolarHBondContact O-CG 3.15Å; C320-L324 PolarHBondContact O-N 3.46Å; E321-L324 PolarHBondContact O-N 3.42Å; L322-L324 PolarHBondContact O-N 2.9Å; L324-S327 PolarHBondContact O-N 3.34Å; L324-I328 VanDerWaalsContact O-CG1 3.31Å; L324-I328 WeakPolarHBondContact O-CG1 3.24Å; L324-I328 PolarHBondContact O-N 3.3Å
325	L	94	Very high	92.9	Very high	17 Å²	17	40.7 Å²	40.7	9%	0.089	20%	0.2	C	C	.	.	H	α-helix	trans	-61.3	-48.8	179.6	-178.5	57	0	0	0	111.8	E321 L322 S327 I328 S329 V432 Q436 I455	E321-L325 VanDerWaalsContact O-CB 3.26Å; E321-L325 WeakPolarHBondContact O-CB 3.33Å; E321-L325 PolarHBondContact O-N 3.39Å; L322-L325 PolarHBondContact O-N 3.31Å; L325-S327 VanDerWaalsContact C-N 3.35Å; L325-I328 PolarHBondContact O-N 3.37Å; L325-S329 VanDerWaalsContact O-CB 3.25Å; L325-S329 WeakPolarHBondContact O-CB 3.23Å; L325-S329 PolarHBondContact O-N 3.26Å; L325-S329 PolarHBondContact O-OG 2.96Å; L325-V432 HydrophobicContact CD1-CG1 3.47Å; L325-V432 VanDerWaalsContact CD1-CG1 3.47Å; L325-Q436 HydrophobicContact CD1-CG 4.07Å; L325-Q436 HydrophobicContact CD2-CG 4.09Å; L325-I455 HydrophobicContact CD2-CB 4.38Å; L325-I455 HydrophobicContact CD2-CD1 4.12Å; L325-I455 HydrophobicContact CD2-CG2 3.6Å; L325-I455 HydrophobicContact CG-CG2 4.01Å
326	V	94.8	Very high	92.9	Very high	9 Å²	9	40.1 Å²	40.1	6%	0.055	20%	0.196	C	C	.	.	H	α-helix	trans	-64.8	-40.5	177.8	172.1	0	0	0	0	110.9	A91 A297 V300 L322 T330	A91-V326 HydrophobicContact CB-CG2 3.82Å; A297-V326 HydrophobicContact CB-CG1 4.29Å; V300-V326 HydrophobicContact CB-CG1 4.27Å; V300-V326 HydrophobicContact CG1-CG1 4.42Å; V300-V326 HydrophobicContact CG1-CG2 3.97Å; V300-V326 HydrophobicContact CG2-CG1 4.45Å; L322-V326 HydrophobicContact CD1-CG2 3.9Å; L322-V326 HydrophobicContact CG-CG2 4.15Å; L322-V326 WeakPolarHBondContact O-CB 3.34Å; L322-V326 VanDerWaalsContact O-CG2 3.27Å; L322-V326 WeakPolarHBondContact O-CG2 3.26Å; L322-V326 PolarHBondContact O-N 3.43Å; V326-T330 WeakPolarHBondContact O-CB 3.41Å; V326-T330 PolarHBondContact O-N 3.33Å; V326-T330 PolarHBondContact O-OG1 2.97Å
327	S	95	Very high	92.8	Very high	15 Å²	15	34.5 Å²	34.5	11%	0.105	17%	0.173	C	C	.	.	H	α-helix	trans	-61	-49.5	177.6	-175.5	0	0	0	0	111.6	S293 F323 L324 L325 S331	S293-S327 WeakPolarHBondContact CB-O 3.21Å; F323-S327 VanDerWaalsContact O-CB 3.25Å; F323-S327 WeakPolarHBondContact O-CB 3.31Å; F323-S327 PolarHBondContact O-N 2.95Å; L324-S327 PolarHBondContact O-N 3.34Å; L325-S327 VanDerWaalsContact C-N 3.35Å; S327-S331 VanDerWaalsContact O-CB 3.3Å; S327-S331 WeakPolarHBondContact O-CB 3.41Å; S327-S331 PolarHBondContact O-N 2.9Å; S327-S331 PolarHBondContact O-OG 3.45Å
328	I	94.7	Very high	92.5	Very high	53 Å²	53	26.9 Å²	26.9	27%	0.272	15%	0.145	S	C	.	.	H	α-helix	trans	-68.9	-49.5	-179.2	-62.3	165.5	0	0	0	110.9	L324 L325 T330 S331 V332 L428 V432	L324-I328 VanDerWaalsContact O-CG1 3.31Å; L324-I328 WeakPolarHBondContact O-CG1 3.24Å; L324-I328 PolarHBondContact O-N 3.3Å; L325-I328 PolarHBondContact O-N 3.37Å; I328-T330 VanDerWaalsContact C-N 3.34Å; I328-T330 PolarHBondContact O-N 3.24Å; I328-S331 WeakPolarHBondContact O-CA 2.99Å; I328-S331 WeakPolarHBondContact O-CB 3.37Å; I328-S331 PolarHBondContact O-N 3.45Å; I328-S331 VanDerWaalsContact O-N 3.09Å; I328-V332 HydrophobicContact CG2-CG2 4.42Å; I328-V332 WeakPolarHBondContact O-CG2 3.41Å; I328-V332 PolarHBondContact O-N 3.49Å; I328-L428 HydrophobicContact CG2-CD1 3.97Å; I328-L428 HydrophobicContact CG2-CD2 3.91Å; I328-L428 HydrophobicContact CG2-CG 3.75Å; I328-V432 HydrophobicContact CB-CG2 4.29Å; I328-V432 HydrophobicContact CD1-CG2 4.26Å; I328-V432 HydrophobicContact CG2-CG2 3.65Å
329	S	94	Very high	92.4	Very high	9 Å²	9	26.3 Å²	26.3	6%	0.063	14%	0.143	C	C	.	.	H	α-helix	trans	-60.9	-43.8	-178.3	-49.3	0	0	0	0	111.2	L325 S331 V332 I333 N459	L325-S329 VanDerWaalsContact O-CB 3.25Å; L325-S329 WeakPolarHBondContact O-CB 3.23Å; L325-S329 PolarHBondContact O-N 3.26Å; L325-S329 PolarHBondContact O-OG 2.96Å; S329-S331 PolarHBondContact O-N 3Å; S329-V332 PolarHBondContact O-N 3.29Å; S329-I333 VanDerWaalsContact O-CG1 3.28Å; S329-I333 WeakPolarHBondContact O-CG1 3.41Å; S329-I333 PolarHBondContact O-N 3.11Å; S329-N459 WeakPolarHBondContact CB-OD1 3.32Å; S329-N459 PolarHBondContact OG-ND2 3.37Å; S329-N459 PolarHBondContact OG-OD1 2.82Å; S329-N459 VanDerWaalsContact OG-OD1 3.11Å
330	T	94.3	Very high	92	Very high	8 Å²	8	27.2 Å²	27.2	5%	0.049	15%	0.149	C	C	.	.	H	α-helix	trans	-65.1	-40.3	175.4	-57.8	0	0	0	0	111.3	L84 V326 I328 V332 I333 L334	L84-T330 HydrophobicContact CD1-CG2 4.09Å; V326-T330 WeakPolarHBondContact O-CB 3.41Å; V326-T330 PolarHBondContact O-N 3.33Å; V326-T330 PolarHBondContact O-OG1 2.97Å; I328-T330 VanDerWaalsContact C-N 3.34Å; I328-T330 PolarHBondContact O-N 3.24Å; T330-V332 VanDerWaalsContact C-N 3.33Å; T330-V332 PolarHBondContact O-N 3.17Å; T330-I333 PolarHBondContact O-N 3.35Å; T330-L334 HydrophobicContact CG2-CD1 3.78Å; T330-L334 HydrophobicContact CG2-CG 4.16Å; T330-L334 WeakPolarHBondContact O-CB 3.12Å; T330-L334 WeakPolarHBondContact O-CG 3.3Å; T330-L334 PolarHBondContact O-N 3.43Å
331	S	94.3	Very high	91.5	Very high	24 Å²	24	24.4 Å²	24.4	17%	0.168	13%	0.131	C	C	.	.	H	α-helix	trans	-58.6	-46.2	175.3	-64.2	0	0	0	0	111.3	S293 S327 I328 S329 L334 M335	S293-S331 WeakPolarHBondContact CB-OG 3.45Å; S293-S331 PolarHBondContact OG-OG 3.02Å; S327-S331 VanDerWaalsContact O-CB 3.3Å; S327-S331 WeakPolarHBondContact O-CB 3.41Å; S327-S331 PolarHBondContact O-N 2.9Å; S327-S331 PolarHBondContact O-OG 3.45Å; I328-S331 WeakPolarHBondContact O-CA 2.99Å; I328-S331 WeakPolarHBondContact O-CB 3.37Å; I328-S331 PolarHBondContact O-N 3.45Å; I328-S331 VanDerWaalsContact O-N 3.09Å; S329-S331 PolarHBondContact O-N 3Å; S331-L334 PolarHBondContact O-N 3.34Å; S331-M335 WeakPolarHBondContact O-CB 3.48Å; S331-M335 WeakPolarHBondContact O-CG 3.49Å; S331-M335 PolarHBondContact O-N 3.41Å
332	V	93.7	Very high	90.9	Very high	1 Å²	1	25 Å²	25	1%	0.006	14%	0.139	C	C	.	.	H	α-helix	trans	-64.2	-46.6	179.6	171.8	0	0	0	0	111.4	I328 S329 T330 L334 M335 Q336 L425 L428 E429 L466	I328-V332 HydrophobicContact CG2-CG2 4.42Å; I328-V332 WeakPolarHBondContact O-CG2 3.41Å; I328-V332 PolarHBondContact O-N 3.49Å; S329-V332 PolarHBondContact O-N 3.29Å; T330-V332 VanDerWaalsContact C-N 3.33Å; T330-V332 PolarHBondContact O-N 3.17Å; V332-L334 VanDerWaalsContact C-N 3.32Å; V332-L334 PolarHBondContact O-N 3.49Å; V332-M335 PolarHBondContact O-N 3.26Å; V332-Q336 WeakPolarHBondContact O-CG 3.41Å; V332-Q336 PolarHBondContact O-N 3.04Å; V332-L425 HydrophobicContact CG2-CD2 4.42Å; V332-L428 HydrophobicContact CG2-CD2 3.94Å; V332-L428 HydrophobicContact CG2-CG 4.37Å; V332-E429 HydrophobicContact CG1-CB 4.34Å; V332-E429 HydrophobicContact CG1-CG 4.48Å; V332-E429 WeakPolarHBondContact CG1-OE2 3.39Å; V332-L466 HydrophobicContact CG1-CD1 3.69Å
333	I	92.3	Very high	90.6	Very high	16 Å²	16	24.7 Å²	24.7	8%	0.082	14%	0.138	C	C	.	.	H	α-helix	trans	-60.4	-42.5	177.5	-68	166.9	0	0	0	110.9	F80 L84 S329 T330 Q336 H337 A462	F80-I333 HydrophobicContact CE2-CG2 3.63Å; F80-I333 WeakPolarHBondContact CE2-O 3.35Å; F80-I333 HydrophobicContact CZ-CG2 4.02Å; L84-I333 HydrophobicContact CD1-CG2 4.03Å; S329-I333 VanDerWaalsContact O-CG1 3.28Å; S329-I333 WeakPolarHBondContact O-CG1 3.41Å; S329-I333 PolarHBondContact O-N 3.11Å; T330-I333 PolarHBondContact O-N 3.35Å; I333-Q336 PolarHBondContact O-N 2.82Å; I333-H337 PolarHBondContact O-N 3.22Å; I333-A462 HydrophobicContact CD1-CB 4.49Å; I333-A462 HydrophobicContact CG1-CB 3.9Å
334	L	92.3	Very high	90.2	Very high	0 Å²	0	22.7 Å²	22.7	0%	0	13%	0.131	C	C	.	.	H	α-helix	trans	-68.1	-39.5	177.1	-71.8	175.1	0	0	0	112.6	F80 L84 V289 T330 S331 V332 Q336 H337 L338	F80-L334 HydrophobicContact CE1-CD2 4.37Å; F80-L334 HydrophobicContact CZ-CD2 4.1Å; L84-L334 HydrophobicContact CD2-CD2 3.76Å; V289-L334 HydrophobicContact CB-CB 4.49Å; V289-L334 HydrophobicContact CG1-CB 4.23Å; V289-L334 HydrophobicContact CG2-CB 4.05Å; T330-L334 HydrophobicContact CG2-CD1 3.78Å; T330-L334 HydrophobicContact CG2-CG 4.16Å; T330-L334 WeakPolarHBondContact O-CB 3.12Å; T330-L334 WeakPolarHBondContact O-CG 3.3Å; T330-L334 PolarHBondContact O-N 3.43Å; S331-L334 PolarHBondContact O-N 3.34Å; V332-L334 VanDerWaalsContact C-N 3.32Å; V332-L334 PolarHBondContact O-N 3.49Å; L334-Q336 VanDerWaalsContact C-N 3.33Å; L334-Q336 PolarHBondContact O-N 3.36Å; L334-H337 PolarHBondContact O-N 3.46Å; L334-L338 WeakPolarHBondContact O-CB 3.46Å; L334-L338 PolarHBondContact O-N 3.34Å
335	M	91.4	Very high	89.8	Confident	18 Å²	18	18.9 Å²	18.9	9%	0.089	11%	0.111	C	C	.	.	H	α-helix	trans	-61.7	-41.4	176.4	-74.5	-75.2	-80.4	0	0	111.5	M286 V289 S331 V332 H337 L339 L425	M286-M335 HydrophobicContact CE-CE 3.62Å; M286-M335 HydrophobicContact CE-SD 3.68Å; M286-M335 HydrophobicContact SD-CE 3.43Å; M286-M335 WeakPolarHBondContact SD-CE 3.37Å; M286-M335 HydrophobicContact SD-SD 3.41Å; V289-M335 HydrophobicContact CB-CG 4.45Å; V289-M335 HydrophobicContact CB-SD 4.23Å; V289-M335 HydrophobicContact CG1-CG 3.67Å; V289-M335 HydrophobicContact CG1-SD 3.97Å; V289-M335 HydrophobicContact CG2-CG 4.03Å; V289-M335 HydrophobicContact CG2-SD 3.72Å; S331-M335 WeakPolarHBondContact O-CB 3.48Å; S331-M335 WeakPolarHBondContact O-CG 3.49Å; S331-M335 PolarHBondContact O-N 3.41Å; V332-M335 PolarHBondContact O-N 3.26Å; M335-H337 PolarHBondContact O-N 3.49Å; M335-L339 HydrophobicContact CE-CD1 3.34Å; M335-L339 WeakPolarHBondContact O-CA 3.4Å; M335-L339 VanDerWaalsContact O-CB 3.25Å; M335-L339 WeakPolarHBondContact O-CB 3.42Å; M335-L339 PolarHBondContact O-N 2.9Å; M335-L339 HydrophobicContact SD-CD1 3.64Å; M335-L339 HydrophobicContact SD-CG 4.38Å; M335-L425 HydrophobicContact CB-CD1 3.91Å; M335-L425 HydrophobicContact CB-CD2 3.89Å; M335-L425 HydrophobicContact CE-CD2 4.14Å; M335-L425 HydrophobicContact CG-CD2 4.11Å
336	Q	87.9	Confident	89.5	Confident	32 Å²	32	18.3 Å²	18.3	15%	0.15	11%	0.108	C	C	.	.	H	α-helix	trans	-58.3	-36.3	175.4	-72.1	174.3	38.6	0	0	112.5	V332 I333 L334 A462 L466	V332-Q336 WeakPolarHBondContact O-CG 3.41Å; V332-Q336 PolarHBondContact O-N 3.04Å; I333-Q336 PolarHBondContact O-N 2.82Å; L334-Q336 VanDerWaalsContact C-N 3.33Å; L334-Q336 PolarHBondContact O-N 3.36Å; Q336-A462 PolarHBondContact NE2-O 2.87Å; Q336-A462 VanDerWaalsContact NE2-O 3.15Å; Q336-L466 HydrophobicContact CG-CD2 3.49Å; Q336-L466 VanDerWaalsContact CG-CD2 3.49Å; Q336-L466 HydrophobicContact CG-CG 3.98Å
337	H	86.9	Confident	89.3	Confident	38 Å²	38	17.9 Å²	17.9	18%	0.176	11%	0.105	C	C	.	.	H	α-helix	trans	-83.9	-42.7	-177.6	-175.2	67.9	0	0	0	113.3	F80 Y254 I333 L334 M335	F80-H337 HydrophobicContact CD1-CB 4.16Å; F80-H337 AromaticContact CD1-CD2 3.76Å; F80-H337 AromaticContact CD1-CE1 3.99Å; F80-H337 AromaticContact CD1-CG 3.54Å; F80-H337 AromaticContact CD1-ND1 3.69Å; F80-H337 HydrophobicContact CD2-CB 3.78Å; F80-H337 AromaticContact CD2-CG 3.83Å; F80-H337 AromaticContact CD2-ND1 3.8Å; F80-H337 HydrophobicContact CE1-CB 3.75Å; F80-H337 AromaticContact CE1-CD2 3.65Å; F80-H337 AromaticContact CE1-CG 3.51Å; F80-H337 HydrophobicContact CE2-CB 3.35Å; F80-H337 AromaticContact CE2-CG 3.81Å; F80-H337 HydrophobicContact CG-CB 4.16Å; F80-H337 AromaticContact CG-CG 3.69Å; F80-H337 AromaticContact CG-ND1 3.48Å; F80-H337 WeakPolarHBondContact CG-ND1 3.36Å; F80-H337 HydrophobicContact CZ-CB 3.32Å; F80-H337 AromaticContact CZ-CG 3.65Å; Y254-H337 AromaticContact CD1-NE2 3.85Å; Y254-H337 AromaticContact CE1-CE1 3.51Å; Y254-H337 AromaticContact CE1-NE2 3.03Å; Y254-H337 WeakPolarHBondContact CE1-NE2 3.23Å; Y254-H337 AromaticContact CZ-NE2 3.54Å; Y254-H337 PolarHBondContact OH-NE2 2.92Å; I333-H337 PolarHBondContact O-N 3.22Å; L334-H337 PolarHBondContact O-N 3.46Å; M335-H337 PolarHBondContact O-N 3.49Å
338	L	86.7	Confident	89.1	Confident	15 Å²	15	19 Å²	19	8%	0.079	11%	0.109	C	C	.	.	H	α-helix	trans	-80	-23.2	-178.6	-70.3	169.2	0	0	0	112.4	R285 E288 V289 L334 P340	R285-L338 HydrophobicContact CB-CB 4.46Å; R285-L338 WeakPolarHBondContact CD-O 3.23Å; R285-L338 PolarHBondContact NH1-O 2.79Å; E288-L338 HydrophobicContact CB-CD1 4.46Å; E288-L338 HydrophobicContact CG-CD1 4.07Å; V289-L338 HydrophobicContact CG2-CB 4.43Å; V289-L338 HydrophobicContact CG2-CD1 3.49Å; V289-L338 VanDerWaalsContact CG2-CD1 3.49Å; L334-L338 WeakPolarHBondContact O-CB 3.46Å; L334-L338 PolarHBondContact O-N 3.34Å; L338-P340 VanDerWaalsContact O-CD 3.26Å; L338-P340 WeakPolarHBondContact O-CD 3.02Å
339	L	86.5	Confident	88.8	Confident	11 Å²	11	18.2 Å²	18.2	6%	0.058	10%	0.103	C	C	.	.	S	Bend	trans	-117	67.1	174.8	-54.2	175.9	0	0	0	110.2	F282 M286 M335 Y343 I421	F282-L339 HydrophobicContact CD2-CD2 3.9Å; F282-L339 HydrophobicContact CE2-CD1 3.99Å; F282-L339 HydrophobicContact CE2-CD2 3.96Å; M286-L339 HydrophobicContact SD-CD1 4.18Å; M335-L339 HydrophobicContact CE-CD1 3.34Å; M335-L339 WeakPolarHBondContact O-CA 3.4Å; M335-L339 VanDerWaalsContact O-CB 3.25Å; M335-L339 WeakPolarHBondContact O-CB 3.42Å; M335-L339 PolarHBondContact O-N 2.9Å; M335-L339 HydrophobicContact SD-CD1 3.64Å; M335-L339 HydrophobicContact SD-CG 4.38Å; L339-Y343 HydrophobicContact CD2-CD1 3.63Å; L339-Y343 HydrophobicContact CD2-CE1 3.44Å; L339-Y343 VanDerWaalsContact CD2-CE1 3.44Å; L339-I421 HydrophobicContact CD1-CG2 4.24Å
340	P	83.8	Confident	88.5	Confident	35 Å²	35	17.9 Å²	17.9	23%	0.227	10%	0.101	C	C	.	.			trans	-61.7	158.2	176.3	28.1	-34.2	0	0	0	110.5	L338 S342 Y343 C344	L338-P340 VanDerWaalsContact O-CD 3.26Å; L338-P340 WeakPolarHBondContact O-CD 3.02Å; P340-S342 PolarHBondContact O-N 2.85Å; P340-S342 VanDerWaalsContact O-N 3.16Å; P340-Y343 WeakPolarHBondContact O-CB 3.42Å; P340-Y343 PolarHBondContact O-N 2.88Å; P340-C344 PolarHBondContact O-N 3.01Å
341	A	82.5	Confident	88.4	Confident	15 Å²	15	17.5 Å²	17.5	12%	0.124	10%	0.098	C	C	.	.	H	α-helix	trans	-55.1	-36.9	-178.6	0	0	0	0	0	113	L72 Y343 C344 D345 L473	L72-A341 HydrophobicContact CD1-CB 3.99Å; A341-Y343 VanDerWaalsContact C-N 3.34Å; A341-Y343 PolarHBondContact O-N 2.82Å; A341-C344 PolarHBondContact O-N 2.97Å; A341-D345 PolarHBondContact O-N 3.16Å; A341-L473 HydrophobicContact CB-CD2 4.49Å
342	S	81.7	Confident	88.1	Confident	51 Å²	51	17.7 Å²	17.7	36%	0.357	10%	0.102	S	C	.	.	H	α-helix	trans	-65.5	-34.1	176.6	61.8	0	0	0	0	113.1	P340 L346	P340-S342 PolarHBondContact O-N 2.85Å; P340-S342 VanDerWaalsContact O-N 3.16Å; S342-L346 PolarHBondContact O-N 3.22Å
343	Y	86	Confident	87.8	Confident	0 Å²	0	18.4 Å²	18.4	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-74.1	-38.7	174.3	-179	-105.9	0	0	0	111.7	P260 D281 F282 R285 L339 P340 A341 D345 L346 L347	P260-Y343 HydrophobicContact CG-CE2 4.28Å; D281-Y343 WeakPolarHBondContact OD2-CE2 3.29Å; D281-Y343 PolarHBondContact OD2-OH 3.26Å; F282-Y343 WeakPolarHBondContact CA-OH 3.45Å; F282-Y343 HydrophobicContact CD2-CE1 4.38Å; F282-Y343 PolarHBondContact N-OH 2.6Å; R285-Y343 VanDerWaalsContact CZ-CE2 3.42Å; R285-Y343 VanDerWaalsContact NH2-CE2 3.31Å; L339-Y343 HydrophobicContact CD2-CD1 3.63Å; L339-Y343 HydrophobicContact CD2-CE1 3.44Å; L339-Y343 VanDerWaalsContact CD2-CE1 3.44Å; P340-Y343 WeakPolarHBondContact O-CB 3.42Å; P340-Y343 PolarHBondContact O-N 2.88Å; A341-Y343 VanDerWaalsContact C-N 3.34Å; A341-Y343 PolarHBondContact O-N 2.82Å; Y343-D345 VanDerWaalsContact C-N 3.27Å; Y343-D345 PolarHBondContact O-N 3.01Å; Y343-L346 HydrophobicContact CD2-CD2 4.01Å; Y343-L346 HydrophobicContact CE2-CD2 4.31Å; Y343-L346 WeakPolarHBondContact O-CB 3.33Å; Y343-L346 PolarHBondContact O-N 3.34Å; Y343-L347 HydrophobicContact CD1-CD1 3.65Å; Y343-L347 HydrophobicContact CD1-CG 4.45Å; Y343-L347 HydrophobicContact CE1-CD1 3.31Å; Y343-L347 HydrophobicContact CE1-CG 4.15Å; Y343-L347 HydrophobicContact CG-CD1 4.44Å; Y343-L347 WeakPolarHBondContact O-CG 3.37Å; Y343-L347 PolarHBondContact O-N 2.84Å
344	C	88	Confident	87.7	Confident	15 Å²	15	17.7 Å²	17.7	10%	0.101	10%	0.101	C	C	.	.	H	α-helix	trans	-62.4	-37.1	172.7	-65.7	0	0	0	0	111.6	P340 A341 L347 H348	P340-C344 PolarHBondContact O-N 3.01Å; A341-C344 PolarHBondContact O-N 2.97Å; C344-L347 PolarHBondContact O-N 2.95Å; C344-H348 WeakPolarHBondContact O-CB 3.4Å; C344-H348 PolarHBondContact O-N 2.88Å
345	D	85.7	Confident	87.6	Confident	14 Å²	14	17.7 Å²	17.7	8%	0.075	10%	0.101	C	C	.	.	H	α-helix	trans	-66.3	-45.6	173.4	-179.3	53.1	0	0	0	112	I69 A341 Y343 L347 H348 K349 Y477	I69-D345 HydrophobicContact CD1-CB 3.52Å; I69-D345 WeakPolarHBondContact CD1-OD1 3.4Å; A341-D345 PolarHBondContact O-N 3.16Å; Y343-D345 VanDerWaalsContact C-N 3.27Å; Y343-D345 PolarHBondContact O-N 3.01Å; D345-L347 VanDerWaalsContact C-N 3.29Å; D345-L347 PolarHBondContact O-N 3.1Å; D345-H348 WeakPolarHBondContact O-CA 3.46Å; D345-H348 WeakPolarHBondContact O-CB 3.49Å; D345-H348 PolarHBondContact O-N 3.34Å; D345-K349 VanDerWaalsContact O-CG 3.29Å; D345-K349 WeakPolarHBondContact O-CG 3.49Å; D345-K349 PolarHBondContact O-N 2.98Å; D345-K349 WeakPolarHBondContact OD1-CE 3.4Å; D345-K349 IonicContact OD1-NZ 2.79Å; D345-K349 WeakPolarHBondContact OD2-CE 3.32Å; D345-K349 IonicContact OD2-NZ 2.65Å; D345-K349 PolarHBondContact OD2-NZ 3.49Å; D345-Y477 PolarHBondContact OD1-OH 2.84Å
346	L	87.3	Confident	87.6	Confident	6 Å²	6	17.4 Å²	17.4	3%	0.031	10%	0.101	C	C	.	.	H	α-helix	trans	-52	-47.9	172.6	169.7	66.3	0	0	0	112.1	P260 H262 L278 S342 Y343 H348 K349 A350	P260-L346 HydrophobicContact CB-CD2 3.87Å; P260-L346 HydrophobicContact CG-CD2 3.63Å; P260-L346 WeakPolarHBondContact O-CD2 3.4Å; H262-L346 HydrophobicContact CB-CD1 3.5Å; H262-L346 VanDerWaalsContact CB-CD1 3.5Å; L278-L346 HydrophobicContact CD1-CG 4.41Å; L278-L346 HydrophobicContact CD2-CD2 3.78Å; L278-L346 HydrophobicContact CD2-CG 4.08Å; S342-L346 PolarHBondContact O-N 3.22Å; Y343-L346 HydrophobicContact CD2-CD2 4.01Å; Y343-L346 HydrophobicContact CE2-CD2 4.31Å; Y343-L346 WeakPolarHBondContact O-CB 3.33Å; Y343-L346 PolarHBondContact O-N 3.34Å; L346-H348 VanDerWaalsContact C-N 3.33Å; L346-H348 PolarHBondContact O-N 2.86Å; L346-K349 PolarHBondContact O-N 3.47Å; L346-A350 PolarHBondContact O-N 2.95Å
347	L	90.6	Very high	87.8	Confident	0 Å²	0	16.5 Å²	16.5	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-64	-38.3	177.5	-70.8	165.4	0	0	0	112.3	L278 F282 Y343 C344 D345 A351 F411 F415	L278-L347 HydrophobicContact CB-CD2 3.91Å; L278-L347 HydrophobicContact CD1-CD2 4.42Å; L278-L347 HydrophobicContact CD2-CD2 4.43Å; L278-L347 HydrophobicContact CG-CD2 4.49Å; F282-L347 HydrophobicContact CD2-CD1 4.11Å; Y343-L347 HydrophobicContact CD1-CD1 3.65Å; Y343-L347 HydrophobicContact CD1-CG 4.45Å; Y343-L347 HydrophobicContact CE1-CD1 3.31Å; Y343-L347 HydrophobicContact CE1-CG 4.15Å; Y343-L347 HydrophobicContact CG-CD1 4.44Å; Y343-L347 WeakPolarHBondContact O-CG 3.37Å; Y343-L347 PolarHBondContact O-N 2.84Å; C344-L347 PolarHBondContact O-N 2.95Å; D345-L347 VanDerWaalsContact C-N 3.29Å; D345-L347 PolarHBondContact O-N 3.1Å; L347-A351 VanDerWaalsContact O-CB 3.28Å; L347-A351 WeakPolarHBondContact O-CB 3.48Å; L347-A351 PolarHBondContact O-N 3.3Å; L347-F411 HydrophobicContact CD2-CE2 3.75Å; L347-F411 HydrophobicContact CD2-CZ 3.83Å; L347-F415 HydrophobicContact CB-CB 4.28Å; L347-F415 HydrophobicContact CB-CD1 3.67Å; L347-F415 HydrophobicContact CB-CD2 4.46Å; L347-F415 HydrophobicContact CB-CE1 4.09Å; L347-F415 HydrophobicContact CB-CG 3.89Å; L347-F415 HydrophobicContact CD1-CD1 3.99Å; L347-F415 HydrophobicContact CD1-CE1 3.54Å; L347-F415 HydrophobicContact CD1-CZ 4.02Å; L347-F415 HydrophobicContact CD2-CE1 4.49Å; L347-F415 HydrophobicContact CD2-CE2 4.43Å; L347-F415 HydrophobicContact CD2-CZ 4.36Å; L347-F415 HydrophobicContact CG-CD1 4.35Å; L347-F415 HydrophobicContact CG-CE1 4.27Å
348	H	90.3	Very high	88	Confident	39 Å²	39	20 Å²	20	18%	0.181	11%	0.113	C	C	.	.	H	α-helix	trans	-64.4	-44.4	175.7	176.1	55.5	0	0	0	112.1	C344 D345 L346 A351 A352 F415 S416 P418 Y477	C344-H348 WeakPolarHBondContact O-CB 3.4Å; C344-H348 PolarHBondContact O-N 2.88Å; D345-H348 WeakPolarHBondContact O-CA 3.46Å; D345-H348 WeakPolarHBondContact O-CB 3.49Å; D345-H348 PolarHBondContact O-N 3.34Å; L346-H348 VanDerWaalsContact C-N 3.33Å; L346-H348 PolarHBondContact O-N 2.86Å; H348-A351 PolarHBondContact O-N 2.88Å; H348-A352 WeakPolarHBondContact O-CB 3.49Å; H348-A352 PolarHBondContact O-N 3.28Å; H348-F415 WeakPolarHBondContact CA-O 3.01Å; H348-F415 PolarHBondContact ND1-O 2.82Å; H348-S416 PolarHBondContact CE1-O 3.31Å; H348-S416 PolarHBondContact ND1-O 3.48Å; H348-P418 HydrophobicContact CB-CB 3.99Å; H348-Y477 AromaticContact CD2-CE1 3.99Å
349	K	88.1	Confident	88.2	Confident	36 Å²	36	25.2 Å²	25.2	16%	0.157	14%	0.135	C	C	.	.	H	α-helix	trans	-61.1	-48.3	177.2	-67.2	178.6	171.8	163.1	0	111.5	H66 D345 L346 A351 A352 H353	H66-K349 HydrophobicContact CB-CD 4.45Å; H66-K349 VanDerWaalsContact ND1-CG 3.33Å; H66-K349 WeakPolarHBondContact ND1-CG 3.28Å; D345-K349 VanDerWaalsContact O-CG 3.29Å; D345-K349 WeakPolarHBondContact O-CG 3.49Å; D345-K349 PolarHBondContact O-N 2.98Å; D345-K349 WeakPolarHBondContact OD1-CE 3.4Å; D345-K349 IonicContact OD1-NZ 2.79Å; D345-K349 WeakPolarHBondContact OD2-CE 3.32Å; D345-K349 IonicContact OD2-NZ 2.65Å; D345-K349 PolarHBondContact OD2-NZ 3.49Å; L346-K349 PolarHBondContact O-N 3.47Å; K349-A351 VanDerWaalsContact C-N 3.32Å; K349-A351 PolarHBondContact O-N 3.32Å; K349-A352 WeakPolarHBondContact O-CB 3.47Å; K349-A352 PolarHBondContact O-N 3.3Å; K349-A352 VanDerWaalsContact O-N 3.17Å; K349-H353 PolarHBondContact O-CD2 3.06Å; K349-H353 PolarHBondContact O-N 2.89Å; K349-H353 VanDerWaalsContact O-N 3.14Å
350	A	88.9	Confident	88.3	Confident	1 Å²	1	26 Å²	26	1%	0.008	14%	0.14	C	C	.	.	H	α-helix	trans	-61	-41.5	176.2	0	0	0	0	0	111.7	V275 L278 L346 A352 H353 L354 F411	V275-A350 HydrophobicContact CG2-CB 4.26Å; L278-A350 HydrophobicContact CD1-CB 3.4Å; L278-A350 VanDerWaalsContact CD1-CB 3.4Å; L346-A350 PolarHBondContact O-N 2.95Å; A350-A352 VanDerWaalsContact C-N 3.34Å; A350-A352 PolarHBondContact O-N 3.43Å; A350-H353 PolarHBondContact O-N 2.84Å; A350-L354 WeakPolarHBondContact O-CB 3.49Å; A350-L354 PolarHBondContact O-N 3.49Å; A350-F411 HydrophobicContact CB-CE1 4.3Å; A350-F411 HydrophobicContact CB-CZ 4.37Å
351	A	91.3	Very high	88.5	Confident	0 Å²	0	29.5 Å²	29.5	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-64.7	-36.8	175.9	0	0	0	0	0	112.7	L347 H348 K349 L354 G355 F411 H412 F415	L347-A351 VanDerWaalsContact O-CB 3.28Å; L347-A351 WeakPolarHBondContact O-CB 3.48Å; L347-A351 PolarHBondContact O-N 3.3Å; H348-A351 PolarHBondContact O-N 2.88Å; K349-A351 VanDerWaalsContact C-N 3.32Å; K349-A351 PolarHBondContact O-N 3.32Å; A351-L354 PolarHBondContact O-N 3Å; A351-G355 PolarHBondContact O-N 2.9Å; A351-G355 VanDerWaalsContact O-N 3.13Å; A351-F411 HydrophobicContact CB-CD1 4.11Å; A351-F411 HydrophobicContact CB-CE1 3.85Å; A351-H412 PolarHBondContact O-CD2 2.73Å; A351-F415 HydrophobicContact CB-CB 3.77Å
352	A	88.8	Confident	88.5	Confident	29 Å²	29	31.9 Å²	31.9	24%	0.24	17%	0.171	C	C	.	.	H	α-helix	trans	-65.7	-37	177.1	0	0	0	0	0	112.7	H348 K349 A350	H348-A352 WeakPolarHBondContact O-CB 3.49Å; H348-A352 PolarHBondContact O-N 3.28Å; K349-A352 WeakPolarHBondContact O-CB 3.47Å; K349-A352 PolarHBondContact O-N 3.3Å; K349-A352 VanDerWaalsContact O-N 3.17Å; A350-A352 VanDerWaalsContact C-N 3.34Å; A350-A352 PolarHBondContact O-N 3.43Å
353	H	87.7	Confident	88.6	Confident	16 Å²	16	33.4 Å²	33.4	7%	0.074	19%	0.186	C	C	.	.	H	α-helix	trans	-74.3	-32.5	173.9	-75.4	-73.9	0	0	0	113.3	L64 H66 H262 I271 K349 A350	L64-H353 WeakPolarHBondContact CD1-ND1 3.04Å; H66-H353 AromaticContact CE1-NE2 3.53Å; H66-H353 AromaticContact NE2-CE1 3.93Å; H66-H353 AromaticContact NE2-NE2 3.12Å; H66-H353 PolarHBondContact NE2-NE2 2.58Å; H66-H353 VanDerWaalsContact NE2-NE2 3.12Å; H262-H353 AromaticContact CE1-CD2 3.32Å; H262-H353 PolarHBondContact CE1-CD2 2.81Å; H262-H353 AromaticContact CE1-NE2 3.34Å; H262-H353 PolarHBondContact CE1-NE2 3.35Å; H262-H353 VanDerWaalsContact CE1-NE2 3.34Å; H262-H353 AromaticContact NE2-CD2 3.31Å; H262-H353 PolarHBondContact NE2-CD2 2.83Å; H262-H353 VanDerWaalsContact NE2-CD2 3.31Å; H262-H353 AromaticContact NE2-NE2 3.83Å; I271-H353 HydrophobicContact CD1-CB 4.2Å; I271-H353 HydrophobicContact CG1-CB 4.41Å; I271-H353 HydrophobicContact CG2-CB 4.03Å; K349-H353 PolarHBondContact O-CD2 3.06Å; K349-H353 PolarHBondContact O-N 2.89Å; K349-H353 VanDerWaalsContact O-N 3.14Å; A350-H353 PolarHBondContact O-N 2.84Å
354	L	89.9	Confident	88.2	Confident	0 Å²	0	39.9 Å²	39.9	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-66.6	-43.8	178	-175.9	65.9	0	0	0	112.2	V275 A350 A351 V400 A401 H408 F411	V275-L354 HydrophobicContact CG1-CD1 4.48Å; V275-L354 HydrophobicContact CG1-CD2 3.83Å; V275-L354 HydrophobicContact CG2-CB 4.16Å; V275-L354 HydrophobicContact CG2-CD1 4.17Å; V275-L354 HydrophobicContact CG2-CD2 4.14Å; V275-L354 HydrophobicContact CG2-CG 4.37Å; A350-L354 WeakPolarHBondContact O-CB 3.49Å; A350-L354 PolarHBondContact O-N 3.49Å; A351-L354 PolarHBondContact O-N 3Å; L354-V400 PolarHBondContact O-N 3.13Å; L354-A401 HydrophobicContact CD1-CB 4Å; L354-A401 HydrophobicContact CG-CB 4.01Å; L354-A401 PolarHBondContact O-N 3.42Å; L354-H408 HydrophobicContact CD2-CB 4.17Å; L354-F411 HydrophobicContact CD2-CD1 3.83Å
355	G	89.6	Confident	87.6	Confident	0 Å²	0	39.8 Å²	39.8	0%	0	22%	0.22	C	C	.	.			trans	67.9	-170.6	-173.2	0	0	0	0	0	113.6	A351 Y398 N399 H412	A351-G355 PolarHBondContact O-N 2.9Å; A351-G355 VanDerWaalsContact O-N 3.13Å; G355-Y398 WeakPolarHBondContact CA-O 3.48Å; G355-N399 WeakPolarHBondContact CA-OD1 3.24Å; G355-H412 PolarHBondContact O-CD2 3.31Å
356	C	91.4	Very high	87	Confident	12 Å²	12	43 Å²	43	8%	0.081	24%	0.244	C	C	.	.			trans	-150.6	157.7	175.8	70.6	0	0	0	0	113.6	V395 N399 H412	C356-V395 PolarHBondContact O-N 2.98Å; C356-N399 PolarHBondContact N-OD1 2.76Å; C356-N399 PolarHBondContact O-OD1 3.44Å; C356-H412 HydrophobicContact CB-CB 4.07Å; C356-H412 PolarHBondContact SG-CE1 2.7Å; C356-H412 PolarHBondContact SG-ND1 3.26Å
357	W	91.9	Very high	86.6	Confident	14 Å²	14	50.3 Å²	50.3	5%	0.053	28%	0.282	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-109.9	132.1	179.7	-67.1	102.8	0	0	0	109.9	W379 V385 Y392 K393 A394 N399 A401 P403	W357-W379 HydrophobicContact CH2-CB 3.6Å; W357-W379 AromaticContact CH2-CD1 3.97Å; W357-W379 HydrophobicContact CH2-CD2 4.29Å; W357-W379 AromaticContact CH2-CG 3.64Å; W357-W379 HydrophobicContact CH2-CG 3.64Å; W357-W379 HydrophobicContact CZ2-CB 3.93Å; W357-W379 AromaticContact CZ2-CD1 3.75Å; W357-W379 AromaticContact CZ2-CG 3.87Å; W357-W379 HydrophobicContact CZ2-CG 3.87Å; W357-V385 HydrophobicContact CH2-CB 3.92Å; W357-V385 HydrophobicContact CH2-CG2 3.49Å; W357-V385 VanDerWaalsContact CH2-CG2 3.49Å; W357-V385 HydrophobicContact CZ3-CB 3.79Å; W357-V385 HydrophobicContact CZ3-CG2 3.67Å; W357-Y392 HydrophobicContact CB-CD1 4.04Å; W357-Y392 HydrophobicContact CB-CG 4.3Å; W357-K393 WeakPolarHBondContact CA-O 3.48Å; W357-A394 HydrophobicContact CE3-CB 4.27Å; W357-A394 HydrophobicContact CH2-CB 4.11Å; W357-A394 HydrophobicContact CZ3-CB 3.73Å; W357-N399 HydrophobicContact CH2-CB 4.31Å; W357-N399 HydrophobicContact CZ2-CB 3.78Å; W357-A401 PolarHBondContact NE1-O 2.63Å; W357-P403 HydrophobicContact CB-CB 4.11Å; W357-P403 HydrophobicContact CD2-CB 4.25Å; W357-P403 HydrophobicContact CD2-CG 3.97Å; W357-P403 HydrophobicContact CG-CB 3.81Å; W357-P403 HydrophobicContact CG-CG 3.94Å
358	Q	91.2	Very high	86.1	Confident	111 Å²	111	54.1 Å²	54.1	52%	0.519	31%	0.305	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-101.6	124.2	170.6	-177	172.6	22.2	0	0	108.8	V360 Y392 K393 V395	Q358-V360 PolarHBondContact O-N 3.39Å; Q358-Y392 CarbonylContact O-C 3.56Å; Q358-Y392 VanDerWaalsContact O-CA 3.28Å; Q358-Y392 WeakPolarHBondContact O-CA 3.24Å; Q358-K393 PolarHBondContact N-O 2.87Å; Q358-K393 PolarHBondContact O-N 3.38Å; Q358-V395 HydrophobicContact CB-CG2 3.64Å
359	K	90.6	Very high	85.7	Confident	125 Å²	125	57.9 Å²	57.9	54%	0.543	33%	0.326	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-65.9	127.9	173.7	-171	178.3	178.9	175.9	0	108.9	N390 Y392	K359-N390 WeakPolarHBondContact CE-OD1 3.2Å; K359-N390 PolarHBondContact NZ-OD1 3.34Å; K359-Y392 HydrophobicContact CB-CD1 4.06Å; K359-Y392 HydrophobicContact CB-CE1 3.88Å; K359-Y392 HydrophobicContact CG-CE1 4.14Å
360	V	89.7	Confident	85.5	Confident	28 Å²	28	59.2 Å²	59.2	17%	0.17	33%	0.333	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-120.9	144.7	177.6	-173.9	0	0	0	0	108.7	Q358 P362 C365 V391 K393	Q358-V360 PolarHBondContact O-N 3.39Å; V360-P362 WeakPolarHBondContact O-CD 3.42Å; V360-C365 WeakPolarHBondContact CG1-SG 3.37Å; V360-V391 PolarHBondContact N-O 3Å; V360-K393 HydrophobicContact CG2-CB 3.69Å
361	D	87.6	Confident	85.3	Confident	107 Å²	107	61.7 Å²	61.7	57%	0.572	35%	0.345	S	S	*	.			trans	-64.3	125.6	176.3	-68.2	-38.2	0	0	0	110.3	A363 L364	D361-A363 PolarHBondContact O-N 3.16Å; D361-A363 VanDerWaalsContact O-N 3.11Å; D361-L364 HydrophobicContact CB-CD1 3.84Å; D361-L364 PolarHBondContact O-N 3.21Å; D361-L364 VanDerWaalsContact O-N 3.11Å
362	P	82.1	Confident	85.1	Confident	65 Å²	65	66.2 Å²	66.2	42%	0.422	37%	0.374	S	S	.	.	G	3₁₀ helix	trans	-57.7	-29.8	-178	-25.1	33.2	0	0	0	113.4	V360 L364 C365 S366 V391	V360-P362 WeakPolarHBondContact O-CD 3.42Å; P362-L364 VanDerWaalsContact C-N 3.32Å; P362-L364 PolarHBondContact O-N 2.61Å; P362-C365 PolarHBondContact O-N 3.46Å; P362-S366 PolarHBondContact O-N 2.66Å; P362-V391 HydrophobicContact CB-CG2 4.13Å; P362-V391 HydrophobicContact CG-CG2 4.19Å
363	A	83.2	Confident	85.1	Confident	83 Å²	83	66.3 Å²	66.3	69%	0.686	37%	0.368	S	S	*	.	G	3₁₀ helix	trans	-64.3	-34.1	-179.8	0	0	0	0	0	113	D361 C365	D361-A363 PolarHBondContact O-N 3.16Å; D361-A363 VanDerWaalsContact O-N 3.11Å; A363-C365 VanDerWaalsContact C-N 3.26Å; A363-C365 PolarHBondContact O-N 3.15Å
364	L	78.6	Confident	85.1	Confident	137 Å²	137	68.3 Å²	68.3	72%	0.717	38%	0.381	S	S	*	.	G	3₁₀ helix	trans	-77.3	-14.5	179.6	-83.2	83.1	0	0	0	112.5	D361 P362	D361-L364 HydrophobicContact CB-CD1 3.84Å; D361-L364 PolarHBondContact O-N 3.21Å; D361-L364 VanDerWaalsContact O-N 3.11Å; P362-L364 VanDerWaalsContact C-N 3.32Å; P362-L364 PolarHBondContact O-N 2.61Å
365	C	74.5	Confident	85	Confident	12 Å²	12	74 Å²	74	8%	0.081	41%	0.408	C	S	.	.	G	3₁₀ helix	trans	-120.7	15.9	-169.8	-64.7	0	0	0	0	114	V360 P362 A363 N367 V368 Q370 L384	V360-C365 WeakPolarHBondContact CG1-SG 3.37Å; P362-C365 PolarHBondContact O-N 3.46Å; A363-C365 VanDerWaalsContact C-N 3.26Å; A363-C365 PolarHBondContact O-N 3.15Å; C365-N367 PolarHBondContact O-N 3.41Å; C365-V368 PolarHBondContact O-N 2.93Å; C365-Q370 PolarHBondContact O-NE2 3.41Å; C365-L384 HydrophobicContact CB-CD1 3.68Å
366	S	73.2	Confident	84.8	Confident	83 Å²	83	81.8 Å²	81.8	58%	0.58	44%	0.444	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.8	-31.9	179.8	60.5	0	0	0	0	113.2	P362	P362-S366 PolarHBondContact O-N 2.66Å
367	N	79	Confident	84.5	Confident	158 Å²	158	83.3 Å²	83.3	85%	0.845	45%	0.454	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.6	-5.4	-175.5	-59.9	-21.7	0	0	0	113.7	C365	C365-N367 PolarHBondContact O-N 3.41Å
368	V	81.1	Confident	84.1	Confident	80 Å²	80	83.8 Å²	83.8	49%	0.485	46%	0.458	S	S	.	.	S	Bend	trans	-100.3	141.2	-177.9	-176.1	0	0	0	0	109.1	C365 Q370 L384	C365-V368 PolarHBondContact O-N 2.93Å; V368-Q370 WeakPolarHBondContact O-CG 3.46Å; V368-Q370 PolarHBondContact O-N 3.19Å; V368-Q370 VanDerWaalsContact O-N 3.16Å; V368-L384 HydrophobicContact CB-CD1 3.66Å; V368-L384 HydrophobicContact CG1-CD1 3.51Å; V368-L384 HydrophobicContact CG1-CG 4.26Å; V368-L384 HydrophobicContact CG2-CD1 4.36Å
369	L	81.7	Confident	84	Confident	119 Å²	119	79.3 Å²	79.3	62%	0.623	44%	0.436	S	S	*	.			trans	-57.5	119.4	177.5	-174	65.8	0	0	0	110.5	H371	L369-H371 VanDerWaalsContact CD2-CE1 3.47Å; L369-H371 WeakPolarHBondContact CD2-CE1 3.32Å; L369-H371 WeakPolarHBondContact CD2-NE2 3.28Å
370	Q	82.6	Confident	83.9	Confident	64 Å²	64	74.4 Å²	74.4	30%	0.299	42%	0.417	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-107.1	125.5	177.5	-63	176.9	22.6	0	0	109.2	C365 V368 L384	C365-Q370 PolarHBondContact O-NE2 3.41Å; V368-Q370 WeakPolarHBondContact O-CG 3.46Å; V368-Q370 PolarHBondContact O-N 3.19Å; V368-Q370 VanDerWaalsContact O-N 3.16Å; Q370-L384 HydrophobicContact CG-CB 4.5Å
371	H	85.6	Confident	83.8	Confident	53 Å²	53	78.9 Å²	78.9	25%	0.245	44%	0.436	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.9	146.6	175.6	-61.2	-80	0	0	0	111	L369 W379 L384 V385 K386	L369-H371 VanDerWaalsContact CD2-CE1 3.47Å; L369-H371 WeakPolarHBondContact CD2-CE1 3.32Å; L369-H371 WeakPolarHBondContact CD2-NE2 3.28Å; H371-W379 HydrophobicContact CB-CH2 3.49Å; H371-W379 VanDerWaalsContact CB-CH2 3.49Å; H371-W379 HydrophobicContact CB-CZ3 3.47Å; H371-W379 VanDerWaalsContact CB-CZ3 3.47Å; H371-W379 AromaticContact CG-CZ3 3.83Å; H371-L384 PolarHBondContact N-O 3.41Å; H371-V385 CarbonylContact O-C 3.43Å; H371-V385 VanDerWaalsContact O-CA 3.27Å; H371-V385 WeakPolarHBondContact O-CA 3.25Å; H371-V385 WeakPolarHBondContact O-CG1 3.37Å; H371-K386 PolarHBondContact O-N 2.9Å
372	P	87.6	Confident	83.8	Confident	95 Å²	95	75.6 Å²	75.6	62%	0.617	43%	0.427	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-66.6	136.8	166	29.1	-32.7	0	0	0	109.4	T374 W379	P372-T374 PolarHBondContact O-N 2.99Å; P372-W379 WeakPolarHBondContact O-CH2 3.35Å; P372-W379 WeakPolarHBondContact O-CZ2 3.14Å
373	W	89.5	Confident	84.1	Confident	31 Å²	31	73.6 Å²	73.6	12%	0.117	41%	0.414	C	S	.	.	P	Polyproline II helix	trans	-67.7	134.9	175.8	-172.1	76	0	0	0	110.5	E375 W379 V385 K386 H387 I402 P403	W373-E375 HydrophobicContact CE3-CG 4.29Å; W373-E375 HydrophobicContact CH2-CB 4.38Å; W373-E375 HydrophobicContact CH2-CG 3.35Å; W373-E375 HydrophobicContact CZ2-CG 4.25Å; W373-E375 HydrophobicContact CZ3-CG 3.35Å; W373-W379 AromaticContact CD1-NE1 3.76Å; W373-V385 HydrophobicContact CB-CG1 3.25Å; W373-V385 HydrophobicContact CG-CG1 3.91Å; W373-V385 VanDerWaalsContact N-CG1 3.32Å; W373-K386 PolarHBondContact N-O 3.34Å; W373-H387 HydrophobicContact CB-CB 4.1Å; W373-H387 AromaticContact CE3-CD2 3.64Å; W373-H387 AromaticContact CE3-NE2 3.86Å; W373-I402 HydrophobicContact CH2-CB 4.29Å; W373-I402 HydrophobicContact CH2-CG1 3.83Å; W373-I402 HydrophobicContact CH2-CG2 4.14Å; W373-I402 HydrophobicContact CZ2-CB 4.27Å; W373-I402 HydrophobicContact CZ2-CG1 3.99Å; W373-I402 HydrophobicContact CZ2-CG2 4.44Å; W373-P403 HydrophobicContact CD2-CG 4.39Å; W373-P403 HydrophobicContact CG-CG 3.99Å
374	T	87.5	Confident	84.4	Confident	57 Å²	57	70.2 Å²	70.2	35%	0.35	38%	0.384	S	S	.	.			trans	-129.6	143.9	174.5	53.3	0	0	0	0	109.9	P372 E376 C377 W379	P372-T374 PolarHBondContact O-N 2.99Å; T374-E376 VanDerWaalsContact C-N 3.33Å; T374-C377 WeakPolarHBondContact OG1-CB 3.48Å; T374-C377 PolarHBondContact OG1-SG 3.38Å; T374-W379 PolarHBondContact O-NE1 2.84Å
375	E	87	Confident	85	Confident	120 Å²	120	63.7 Å²	63.7	56%	0.561	35%	0.35	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.4	-27	-176.2	-69.5	-168.9	-177.8	0	0	113.3	P268 R272 W373	P268-E375 WeakPolarHBondContact CB-O 3.2Å; R272-E375 VanDerWaalsContact CZ-O 3.26Å; R272-E375 PolarHBondContact NH1-O 2.76Å; R272-E375 PolarHBondContact NH2-O 2.9Å; W373-E375 HydrophobicContact CE3-CG 4.29Å; W373-E375 HydrophobicContact CH2-CB 4.38Å; W373-E375 HydrophobicContact CH2-CG 3.35Å; W373-E375 HydrophobicContact CZ2-CG 4.25Å; W373-E375 HydrophobicContact CZ3-CG 3.35Å
376	E	84.7	Confident	85.6	Confident	164 Å²	164	69 Å²	69	77%	0.766	37%	0.371	S	S	*	.	T	Hydrogen-bonded Turn	trans	-87.2	-12.2	-173	-59.9	178.9	174.5	0	0	113.1	P268 T374	P268-E376 WeakPolarHBondContact CG-O 3.4Å; T374-E376 VanDerWaalsContact C-N 3.33Å
377	C	84.8	Confident	86.4	Confident	43 Å²	43	67 Å²	67	29%	0.291	35%	0.353	S	S	.	.			trans	-97.2	142.1	-176.4	-63.2	0	0	0	0	112.2	T374 W379	T374-C377 WeakPolarHBondContact OG1-CB 3.48Å; T374-C377 PolarHBondContact OG1-SG 3.38Å; C377-W379 HydrophobicContact CB-CZ2 4.19Å
378	M	85	Confident	86.7	Confident	24 Å²	24	62.9 Å²	62.9	12%	0.118	34%	0.337	C	S	.	.			trans	-95.1	114.2	168.3	-174.6	174.1	-80.5	0	0	108.8	V61 I271 Y398 V400	V61-M378 HydrophobicContact CG1-SD 3.85Å; I271-M378 HydrophobicContact CD1-CE 3.77Å; M378-Y398 HydrophobicContact CG-CD1 3.71Å; M378-Y398 HydrophobicContact CG-CG 3.9Å; M378-Y398 HydrophobicContact SD-CD1 3.53Å; M378-Y398 VanDerWaalsContact SD-CD1 3.53Å; M378-Y398 HydrophobicContact SD-CD2 4.14Å; M378-Y398 HydrophobicContact SD-CE1 4.24Å; M378-Y398 HydrophobicContact SD-CG 3.47Å; M378-V400 HydrophobicContact CB-CG2 4.37Å; M378-V400 HydrophobicContact CE-CG2 3.8Å; M378-V400 HydrophobicContact CG-CG2 4.01Å
379	W	89.1	Confident	87	Confident	18 Å²	18	68.5 Å²	68.5	7%	0.068	36%	0.355	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-89.9	122.5	-172.5	-62.4	89.7	0	0	0	111.4	W357 H371 P372 W373 T374 C377 V383 V385 Y398 N399	W357-W379 HydrophobicContact CH2-CB 3.6Å; W357-W379 AromaticContact CH2-CD1 3.97Å; W357-W379 HydrophobicContact CH2-CD2 4.29Å; W357-W379 AromaticContact CH2-CG 3.64Å; W357-W379 HydrophobicContact CH2-CG 3.64Å; W357-W379 HydrophobicContact CZ2-CB 3.93Å; W357-W379 AromaticContact CZ2-CD1 3.75Å; W357-W379 AromaticContact CZ2-CG 3.87Å; W357-W379 HydrophobicContact CZ2-CG 3.87Å; H371-W379 HydrophobicContact CB-CH2 3.49Å; H371-W379 VanDerWaalsContact CB-CH2 3.49Å; H371-W379 HydrophobicContact CB-CZ3 3.47Å; H371-W379 VanDerWaalsContact CB-CZ3 3.47Å; H371-W379 AromaticContact CG-CZ3 3.83Å; P372-W379 WeakPolarHBondContact O-CH2 3.35Å; P372-W379 WeakPolarHBondContact O-CZ2 3.14Å; W373-W379 AromaticContact CD1-NE1 3.76Å; T374-W379 PolarHBondContact O-NE1 2.84Å; C377-W379 HydrophobicContact CB-CZ2 4.19Å; W379-V383 HydrophobicContact CE3-CG1 3.76Å; W379-V383 HydrophobicContact CZ3-CG1 4.08Å; W379-V385 HydrophobicContact CD2-CG2 3.74Å; W379-V385 HydrophobicContact CE3-CG2 3.61Å; W379-V385 HydrophobicContact CG-CG2 4.36Å; W379-V385 HydrophobicContact CH2-CG2 4.21Å; W379-V385 HydrophobicContact CZ2-CG2 4.32Å; W379-V385 HydrophobicContact CZ3-CG2 3.86Å; W379-Y398 CarbonylContact O-C 3.56Å; W379-N399 HydrophobicContact CB-CB 4.38Å; W379-N399 PolarHBondContact N-O 2.95Å; W379-N399 PolarHBondContact O-N 2.79Å; W379-N399 PolarHBondContact O-ND2 3.33Å
380	P	87.6	Confident	87.3	Confident	22 Å²	22	64.9 Å²	64.9	14%	0.143	34%	0.336	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-71.3	162	178.8	27.6	-30.4	0	0	0	111.5	V383 A394	P380-V383 HydrophobicContact CG-CG2 3.69Å; P380-V383 WeakPolarHBondContact O-CG2 3.03Å; P380-V383 PolarHBondContact O-N 3.26Å; P380-A394 VanDerWaalsContact O-CB 3.23Å; P380-A394 WeakPolarHBondContact O-CB 3.35Å
381	Q	88.2	Confident	87.6	Confident	122 Å²	122	62 Å²	62	57%	0.57	32%	0.323	S	S	*	.	T	Hydrogen-bonded Turn	trans	-54.8	138.5	-179.7	-166	176.2	24.7	0	0	112.7	V383 V395 G396 H397	Q381-V383 VanDerWaalsContact C-N 3.31Å; Q381-V383 PolarHBondContact O-N 2.89Å; Q381-V395 PolarHBondContact NE2-O 2.98Å; Q381-G396 WeakPolarHBondContact CA-O 3.33Å; Q381-G396 VanDerWaalsContact CB-O 3.24Å; Q381-G396 WeakPolarHBondContact CB-O 3.07Å; Q381-G396 WeakPolarHBondContact CG-O 3.14Å; Q381-H397 PolarHBondContact N-O 2.81Å
382	G	87	Confident	87.9	Confident	38 Å²	38	60.7 Å²	60.7	39%	0.392	32%	0.316	S	S	.	.	T	Hydrogen-bonded Turn	trans	86.5	-12.6	174.3	0	0	0	0	0	115.6	A394	G382-A394 PolarHBondContact N-O 3.39Å
383	V	89.1	Confident	88	Confident	22 Å²	22	60.4 Å²	60.4	13%	0.133	31%	0.305	C	S	.	.			trans	-65.8	141.2	177.9	-178.9	0	0	0	0	111.3	W379 P380 Q381 V385 A394	W379-V383 HydrophobicContact CE3-CG1 3.76Å; W379-V383 HydrophobicContact CZ3-CG1 4.08Å; P380-V383 HydrophobicContact CG-CG2 3.69Å; P380-V383 WeakPolarHBondContact O-CG2 3.03Å; P380-V383 PolarHBondContact O-N 3.26Å; Q381-V383 VanDerWaalsContact C-N 3.31Å; Q381-V383 PolarHBondContact O-N 2.89Å; V383-V385 HydrophobicContact CG1-CG2 4.13Å; V383-A394 PolarHBondContact O-N 3.5Å
384	L	89.7	Confident	88.1	Confident	12 Å²	12	59 Å²	59	6%	0.063	30%	0.3	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-98.4	129.8	174.7	-63.5	-178.4	0	0	0	110.9	C365 V368 Q370 H371 V391 Y392 K393	C365-L384 HydrophobicContact CB-CD1 3.68Å; V368-L384 HydrophobicContact CB-CD1 3.66Å; V368-L384 HydrophobicContact CG1-CD1 3.51Å; V368-L384 HydrophobicContact CG1-CG 4.26Å; V368-L384 HydrophobicContact CG2-CD1 4.36Å; Q370-L384 HydrophobicContact CG-CB 4.5Å; H371-L384 PolarHBondContact N-O 3.41Å; L384-V391 HydrophobicContact CB-CG1 4.37Å; L384-V391 HydrophobicContact CD2-CG1 4.49Å; L384-Y392 WeakPolarHBondContact CA-O 3.48Å; L384-K393 HydrophobicContact CD2-CB 3.63Å; L384-K393 HydrophobicContact CD2-CG 3.94Å
385	V	90.1	Very high	88.2	Confident	0 Å²	0	59.1 Å²	59.1	0%	0	30%	0.3	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-130.3	138.2	-177	178.9	0	0	0	0	110.7	W357 H371 W373 W379 V383 Y392	W357-V385 HydrophobicContact CH2-CB 3.92Å; W357-V385 HydrophobicContact CH2-CG2 3.49Å; W357-V385 VanDerWaalsContact CH2-CG2 3.49Å; W357-V385 HydrophobicContact CZ3-CB 3.79Å; W357-V385 HydrophobicContact CZ3-CG2 3.67Å; H371-V385 CarbonylContact O-C 3.43Å; H371-V385 VanDerWaalsContact O-CA 3.27Å; H371-V385 WeakPolarHBondContact O-CA 3.25Å; H371-V385 WeakPolarHBondContact O-CG1 3.37Å; W373-V385 HydrophobicContact CB-CG1 3.25Å; W373-V385 HydrophobicContact CG-CG1 3.91Å; W373-V385 VanDerWaalsContact N-CG1 3.32Å; W379-V385 HydrophobicContact CD2-CG2 3.74Å; W379-V385 HydrophobicContact CE3-CG2 3.61Å; W379-V385 HydrophobicContact CG-CG2 4.36Å; W379-V385 HydrophobicContact CH2-CG2 4.21Å; W379-V385 HydrophobicContact CZ2-CG2 4.32Å; W379-V385 HydrophobicContact CZ3-CG2 3.86Å; V383-V385 HydrophobicContact CG1-CG2 4.13Å; V385-Y392 PolarHBondContact N-O 2.87Å; V385-Y392 PolarHBondContact O-N 3.46Å
386	K	88.6	Confident	88	Confident	123 Å²	123	53.9 Å²	53.9	54%	0.535	28%	0.278	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-95.8	124.5	175.5	-170.9	176.1	179.9	178.2	0	110.4	H371 W373 N390	H371-K386 PolarHBondContact O-N 2.9Å; W373-K386 PolarHBondContact N-O 3.34Å; K386-N390 WeakPolarHBondContact CA-O 3.44Å
387	H	88.7	Confident	88	Confident	41 Å²	41	52 Å²	52	19%	0.19	27%	0.269	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-146.3	136.4	177	-171.8	-104.4	0	0	0	110.8	W373 K389 N390 Y392 P403 S404	W373-H387 HydrophobicContact CB-CB 4.1Å; W373-H387 AromaticContact CE3-CD2 3.64Å; W373-H387 AromaticContact CE3-NE2 3.86Å; H387-K389 PolarHBondContact O-N 3.24Å; H387-N390 PolarHBondContact N-O 2.84Å; H387-N390 PolarHBondContact O-N 3.46Å; H387-N390 VanDerWaalsContact O-O 3.06Å; H387-Y392 HydrophobicContact CB-CD2 4.21Å; H387-Y392 HydrophobicContact CB-CE2 4.17Å; H387-P403 HydrophobicContact CB-CB 4.08Å; H387-P403 HydrophobicContact CB-CG 3.95Å; H387-S404 PolarHBondContact CE1-OG 2.86Å; H387-S404 PolarHBondContact ND1-OG 2.86Å
388	S	86.3	Confident	88	Confident	72 Å²	72	51.7 Å²	51.7	50%	0.503	26%	0.262	S	S	.	.	T	Hydrogen-bonded Turn	trans	45.6	52.7	177.5	-64.5	0	0	0	0	114.1	N390	S388-N390 PolarHBondContact O-N 3.02Å; S388-N390 PolarHBondContact O-ND2 2.88Å
389	K	85.8	Confident	88.2	Confident	198 Å²	198	50.5 Å²	50.5	86%	0.861	26%	0.257	S	S	*	.	T	Hydrogen-bonded Turn	trans	62.2	2.6	-178	-55.6	-179.6	-179	179	0	116.6	H387	H387-K389 PolarHBondContact O-N 3.24Å
390	N	88.3	Confident	88.2	Confident	44 Å²	44	49.7 Å²	49.7	24%	0.235	25%	0.254	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-114.3	157.3	179.3	-64.5	-79	0	0	0	110.8	K359 K386 H387 S388 Y392	K359-N390 WeakPolarHBondContact CE-OD1 3.2Å; K359-N390 PolarHBondContact NZ-OD1 3.34Å; K386-N390 WeakPolarHBondContact CA-O 3.44Å; H387-N390 PolarHBondContact N-O 2.84Å; H387-N390 PolarHBondContact O-N 3.46Å; H387-N390 VanDerWaalsContact O-O 3.06Å; S388-N390 PolarHBondContact O-N 3.02Å; S388-N390 PolarHBondContact O-ND2 2.88Å; N390-Y392 HydrophobicContact CB-CD2 4.39Å; N390-Y392 HydrophobicContact CB-CE2 3.6Å
391	V	89.3	Confident	88.3	Confident	4 Å²	4	48.8 Å²	48.8	2%	0.024	25%	0.248	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-104.2	134.8	174.3	-177.8	0	0	0	0	108.6	V360 P362 L384	V360-V391 PolarHBondContact N-O 3Å; P362-V391 HydrophobicContact CB-CG2 4.13Å; P362-V391 HydrophobicContact CG-CG2 4.19Å; L384-V391 HydrophobicContact CB-CG1 4.37Å; L384-V391 HydrophobicContact CD2-CG1 4.49Å
392	Y	91.8	Very high	88.4	Confident	24 Å²	24	45.2 Å²	45.2	9%	0.094	23%	0.232	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-127.2	141.5	-178.5	-63.7	-88.5	0	0	0	110.8	W357 Q358 K359 L384 V385 H387 N390 P403	W357-Y392 HydrophobicContact CB-CD1 4.04Å; W357-Y392 HydrophobicContact CB-CG 4.3Å; Q358-Y392 CarbonylContact O-C 3.56Å; Q358-Y392 VanDerWaalsContact O-CA 3.28Å; Q358-Y392 WeakPolarHBondContact O-CA 3.24Å; K359-Y392 HydrophobicContact CB-CD1 4.06Å; K359-Y392 HydrophobicContact CB-CE1 3.88Å; K359-Y392 HydrophobicContact CG-CE1 4.14Å; L384-Y392 WeakPolarHBondContact CA-O 3.48Å; V385-Y392 PolarHBondContact N-O 2.87Å; V385-Y392 PolarHBondContact O-N 3.46Å; H387-Y392 HydrophobicContact CB-CD2 4.21Å; H387-Y392 HydrophobicContact CB-CE2 4.17Å; N390-Y392 HydrophobicContact CB-CD2 4.39Å; N390-Y392 HydrophobicContact CB-CE2 3.6Å; Y392-P403 HydrophobicContact CD1-CB 4.04Å; Y392-P403 HydrophobicContact CD2-CB 3.46Å; Y392-P403 VanDerWaalsContact CD2-CB 3.46Å; Y392-P403 HydrophobicContact CD2-CG 4.44Å; Y392-P403 HydrophobicContact CE1-CB 4.32Å; Y392-P403 WeakPolarHBondContact CE1-O 3.46Å; Y392-P403 HydrophobicContact CE2-CB 3.76Å; Y392-P403 HydrophobicContact CG-CB 3.62Å
393	K	90.7	Very high	88.4	Confident	90 Å²	90	44 Å²	44	39%	0.391	22%	0.218	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-102.6	132	174.4	-176.3	179.5	178.6	-177.9	0	110.6	W357 Q358 V360 L384 V395	W357-K393 WeakPolarHBondContact CA-O 3.48Å; Q358-K393 PolarHBondContact N-O 2.87Å; Q358-K393 PolarHBondContact O-N 3.38Å; V360-K393 HydrophobicContact CG2-CB 3.69Å; L384-K393 HydrophobicContact CD2-CB 3.63Å; L384-K393 HydrophobicContact CD2-CG 3.94Å; K393-V395 PolarHBondContact O-N 3.34Å
394	A	91.1	Very high	88.3	Confident	1 Å²	1	45.4 Å²	45.4	1%	0.008	23%	0.228	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-67.5	120.5	172.4	0	0	0	0	0	111	W357 P380 G382 V383 N399	W357-A394 HydrophobicContact CE3-CB 4.27Å; W357-A394 HydrophobicContact CH2-CB 4.11Å; W357-A394 HydrophobicContact CZ3-CB 3.73Å; P380-A394 VanDerWaalsContact O-CB 3.23Å; P380-A394 WeakPolarHBondContact O-CB 3.35Å; G382-A394 PolarHBondContact N-O 3.39Å; V383-A394 PolarHBondContact O-N 3.5Å; A394-N399 HydrophobicContact CB-CB 4.29Å; A394-N399 VanDerWaalsContact CB-ND2 3.27Å; A394-N399 WeakPolarHBondContact CB-ND2 3.21Å
395	V	88.6	Confident	88.2	Confident	59 Å²	59	47.1 Å²	47.1	36%	0.358	24%	0.237	S	C	.	.			trans	-103.7	-37.1	-177.9	179	0	0	0	0	112.3	C356 Q358 Q381 K393	C356-V395 PolarHBondContact O-N 2.98Å; Q358-V395 HydrophobicContact CB-CG2 3.64Å; Q381-V395 PolarHBondContact NE2-O 2.98Å; K393-V395 PolarHBondContact O-N 3.34Å
396	G	84.3	Confident	88.2	Confident	10 Å²	10	51.2 Å²	51.2	10%	0.103	26%	0.262	C	S	.	.	S	Bend	trans	-73.3	167.8	177.7	0	0	0	0	0	112.6	Q381 Y398 N399	Q381-G396 WeakPolarHBondContact CA-O 3.33Å; Q381-G396 VanDerWaalsContact CB-O 3.24Å; Q381-G396 WeakPolarHBondContact CB-O 3.07Å; Q381-G396 WeakPolarHBondContact CG-O 3.14Å; G396-Y398 VanDerWaalsContact C-N 3.26Å; G396-Y398 PolarHBondContact O-N 2.8Å; G396-N399 WeakPolarHBondContact CA-OD1 3.49Å; G396-N399 PolarHBondContact N-OD1 3.16Å; G396-N399 PolarHBondContact O-ND2 2.83Å
397	H	84	Confident	88.2	Confident	125 Å²	125	46.9 Å²	46.9	58%	0.579	25%	0.248	S	C	*	.	S	Bend	trans	-56.5	-45.6	174	-67.1	86.5	0	0	0	111.1	L64 Q381	L64-H397 HydrophobicContact CD2-CB 4.11Å; Q381-H397 PolarHBondContact N-O 2.81Å
398	Y	85.3	Confident	88.3	Confident	36 Å²	36	45.2 Å²	45.2	14%	0.141	24%	0.24	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-131	140.6	171.1	-60.9	-65.8	0	0	0	108.7	V61 V62 L64 G355 M378 W379 G396	V61-Y398 HydrophobicContact CG1-CE1 4.02Å; V61-Y398 HydrophobicContact CG1-CE2 4.18Å; V62-Y398 WeakPolarHBondContact CA-OH 3.45Å; V62-Y398 PolarHBondContact N-OH 3.13Å; V62-Y398 VanDerWaalsContact O-CE2 3.27Å; V62-Y398 WeakPolarHBondContact O-CE2 3.1Å; V62-Y398 PolarHBondContact O-OH 3.21Å; L64-Y398 HydrophobicContact CD1-CD2 3.98Å; L64-Y398 HydrophobicContact CG-CD2 4.06Å; L64-Y398 HydrophobicContact CG-CE2 4.15Å; G355-Y398 WeakPolarHBondContact CA-O 3.48Å; M378-Y398 HydrophobicContact CG-CD1 3.71Å; M378-Y398 HydrophobicContact CG-CG 3.9Å; M378-Y398 HydrophobicContact SD-CD1 3.53Å; M378-Y398 VanDerWaalsContact SD-CD1 3.53Å; M378-Y398 HydrophobicContact SD-CD2 4.14Å; M378-Y398 HydrophobicContact SD-CE1 4.24Å; M378-Y398 HydrophobicContact SD-CG 3.47Å; W379-Y398 CarbonylContact O-C 3.56Å; G396-Y398 VanDerWaalsContact C-N 3.26Å; G396-Y398 PolarHBondContact O-N 2.8Å
399	N	89.6	Confident	88.5	Confident	0 Å²	0	46.8 Å²	46.8	0%	0	24%	0.238	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-127.3	106.4	-176.4	-56.6	-86.5	0	0	0	108.9	G355 C356 W357 W379 A394 G396	G355-N399 WeakPolarHBondContact CA-OD1 3.24Å; C356-N399 PolarHBondContact N-OD1 2.76Å; C356-N399 PolarHBondContact O-OD1 3.44Å; W357-N399 HydrophobicContact CH2-CB 4.31Å; W357-N399 HydrophobicContact CZ2-CB 3.78Å; W379-N399 HydrophobicContact CB-CB 4.38Å; W379-N399 PolarHBondContact N-O 2.95Å; W379-N399 PolarHBondContact O-N 2.79Å; W379-N399 PolarHBondContact O-ND2 3.33Å; A394-N399 HydrophobicContact CB-CB 4.29Å; A394-N399 VanDerWaalsContact CB-ND2 3.27Å; A394-N399 WeakPolarHBondContact CB-ND2 3.21Å; G396-N399 WeakPolarHBondContact CA-OD1 3.49Å; G396-N399 PolarHBondContact N-OD1 3.16Å; G396-N399 PolarHBondContact O-ND2 2.83Å
400	V	88.7	Confident	88.8	Confident	0 Å²	0	45 Å²	45	0%	0	23%	0.226	C	C	.	.			trans	-106.3	-16.7	177.6	168.8	0	0	0	0	110.6	P268 I271 R272 L354 M378	P268-V400 HydrophobicContact CB-CG1 3.7Å; P268-V400 HydrophobicContact CB-CG2 4.16Å; P268-V400 HydrophobicContact CG-CG2 4.36Å; P268-V400 VanDerWaalsContact O-CG1 3.3Å; P268-V400 WeakPolarHBondContact O-CG1 3.12Å; I271-V400 HydrophobicContact CB-CG1 4.3Å; I271-V400 HydrophobicContact CD1-CG2 4.23Å; I271-V400 HydrophobicContact CG2-CG1 4.31Å; R272-V400 HydrophobicContact CG-CG1 3.86Å; R272-V400 VanDerWaalsContact CZ-O 3.27Å; R272-V400 PolarHBondContact NE-O 3.06Å; R272-V400 PolarHBondContact NH2-O 2.85Å; L354-V400 PolarHBondContact O-N 3.13Å; M378-V400 HydrophobicContact CB-CG2 4.37Å; M378-V400 HydrophobicContact CE-CG2 3.8Å; M378-V400 HydrophobicContact CG-CG2 4.01Å
401	A	89.8	Confident	89	Confident	3 Å²	3	43.2 Å²	43.2	3%	0.025	22%	0.216	C	C	.	.	S	Bend	trans	-51.7	152.8	178.7	0	0	0	0	0	113.4	L354 W357 P403 H408	L354-A401 HydrophobicContact CD1-CB 4Å; L354-A401 HydrophobicContact CG-CB 4.01Å; L354-A401 PolarHBondContact O-N 3.42Å; W357-A401 PolarHBondContact NE1-O 2.63Å; A401-P403 WeakPolarHBondContact O-CD 3.25Å; A401-H408 HydrophobicContact CB-CB 4.09Å
402	I	90.5	Very high	89.1	Confident	47 Å²	47	44.5 Å²	44.5	24%	0.241	22%	0.222	C	C	.	.			trans	-79.4	121.5	169.8	-55.4	175	0	0	0	107.4	W373 S404 D405 H408	W373-I402 HydrophobicContact CH2-CB 4.29Å; W373-I402 HydrophobicContact CH2-CG1 3.83Å; W373-I402 HydrophobicContact CH2-CG2 4.14Å; W373-I402 HydrophobicContact CZ2-CB 4.27Å; W373-I402 HydrophobicContact CZ2-CG1 3.99Å; W373-I402 HydrophobicContact CZ2-CG2 4.44Å; I402-S404 VanDerWaalsContact C-N 3.29Å; I402-S404 PolarHBondContact O-N 2.96Å; I402-D405 HydrophobicContact CB-CB 3.86Å; I402-D405 HydrophobicContact CG2-CB 4.17Å; I402-D405 PolarHBondContact O-N 3.32Å; I402-D405 VanDerWaalsContact O-N 3.11Å; I402-H408 PolarHBondContact N-ND1 3.5Å
403	P	86.8	Confident	89	Confident	13 Å²	13	48.4 Å²	48.4	8%	0.084	24%	0.239	C	C	.	.	T	Hydrogen-bonded Turn	trans	-61.9	-32.8	-172.2	-23.1	30.4	0	0	0	114.8	W357 W373 H387 Y392 A401	W357-P403 HydrophobicContact CB-CB 4.11Å; W357-P403 HydrophobicContact CD2-CB 4.25Å; W357-P403 HydrophobicContact CD2-CG 3.97Å; W357-P403 HydrophobicContact CG-CB 3.81Å; W357-P403 HydrophobicContact CG-CG 3.94Å; W373-P403 HydrophobicContact CD2-CG 4.39Å; W373-P403 HydrophobicContact CG-CG 3.99Å; H387-P403 HydrophobicContact CB-CB 4.08Å; H387-P403 HydrophobicContact CB-CG 3.95Å; Y392-P403 HydrophobicContact CD1-CB 4.04Å; Y392-P403 HydrophobicContact CD2-CB 3.46Å; Y392-P403 VanDerWaalsContact CD2-CB 3.46Å; Y392-P403 HydrophobicContact CD2-CG 4.44Å; Y392-P403 HydrophobicContact CE1-CB 4.32Å; Y392-P403 WeakPolarHBondContact CE1-O 3.46Å; Y392-P403 HydrophobicContact CE2-CB 3.76Å; Y392-P403 HydrophobicContact CG-CB 3.62Å; A401-P403 WeakPolarHBondContact O-CD 3.25Å
404	S	86.4	Confident	89	Confident	51 Å²	51	48.5 Å²	48.5	36%	0.357	24%	0.24	S	C	.	.	T	Hydrogen-bonded Turn	trans	-86.3	-8.6	179.4	56.6	0	0	0	0	113.8	H387 I402 V406	H387-S404 PolarHBondContact CE1-OG 2.86Å; H387-S404 PolarHBondContact ND1-OG 2.86Å; I402-S404 VanDerWaalsContact C-N 3.29Å; I402-S404 PolarHBondContact O-N 2.96Å; S404-V406 PolarHBondContact O-N 2.95Å
405	D	88.5	Confident	89	Confident	48 Å²	48	49 Å²	49	26%	0.257	24%	0.242	S	C	.	.			trans	-85.5	108.8	-177	-171.6	-0.6	0	0	0	111.3	I402 S407 H408 F409	I402-D405 HydrophobicContact CB-CB 3.86Å; I402-D405 HydrophobicContact CG2-CB 4.17Å; I402-D405 PolarHBondContact O-N 3.32Å; I402-D405 VanDerWaalsContact O-N 3.11Å; D405-S407 PolarHBondContact O-N 3.47Å; D405-S407 WeakPolarHBondContact OD1-CB 3.23Å; D405-S407 PolarHBondContact OD1-N 3.4Å; D405-S407 PolarHBondContact OD1-OG 3.36Å; D405-S407 PolarHBondContact OD2-OG 2.86Å; D405-H408 HydrophobicContact CB-CB 4.42Å; D405-H408 PolarHBondContact O-N 3.34Å; D405-H408 IonicContact OD2-CD2 3.97Å; D405-H408 PolarHBondContact OD2-CD2 3.05Å; D405-H408 IonicContact OD2-CG 3.72Å; D405-H408 IonicContact OD2-NE2 2.66Å; D405-F409 PolarHBondContact O-N 3.13Å
406	V	89.2	Confident	88.9	Confident	86 Å²	86	47.9 Å²	47.9	52%	0.521	24%	0.237	S	C	.	.	H	α-helix	trans	-61.8	-28.2	176.5	-176.2	0	0	0	0	111.3	S404 F409 R410	S404-V406 PolarHBondContact O-N 2.95Å; V406-F409 PolarHBondContact O-N 3.49Å; V406-R410 HydrophobicContact CG1-CG 4.31Å; V406-R410 WeakPolarHBondContact O-CB 3.44Å; V406-R410 WeakPolarHBondContact O-CG 3.05Å; V406-R410 PolarHBondContact O-N 2.83Å
407	S	88.8	Confident	89	Confident	33 Å²	33	54.2 Å²	54.2	23%	0.231	26%	0.262	C	S	.	.	H	α-helix	trans	-69.5	-41.9	-177.8	85.4	0	0	0	0	111.8	K279 D405 R410 F411	K279-S407 PolarHBondContact NZ-OG 3.29Å; D405-S407 PolarHBondContact O-N 3.47Å; D405-S407 WeakPolarHBondContact OD1-CB 3.23Å; D405-S407 PolarHBondContact OD1-N 3.4Å; D405-S407 PolarHBondContact OD1-OG 3.36Å; D405-S407 PolarHBondContact OD2-OG 2.86Å; S407-R410 PolarHBondContact O-N 2.8Å; S407-F411 WeakPolarHBondContact O-CB 3.41Å; S407-F411 PolarHBondContact O-N 2.74Å
408	H	90.4	Very high	89	Confident	6 Å²	6	49.2 Å²	49.2	3%	0.028	24%	0.24	C	C	.	.	H	α-helix	trans	-64.2	-42.6	173.1	-75.1	-155.7	0	0	0	110.9	E276 L354 A401 I402 D405 R410 F411 H412	E276-H408 IonicContact OE1-CD2 3.2Å; E276-H408 IonicContact OE1-NE2 3.92Å; E276-H408 PolarHBondContact OE1-NE2 2.85Å; L354-H408 HydrophobicContact CD2-CB 4.17Å; A401-H408 HydrophobicContact CB-CB 4.09Å; I402-H408 PolarHBondContact N-ND1 3.5Å; D405-H408 HydrophobicContact CB-CB 4.42Å; D405-H408 PolarHBondContact O-N 3.34Å; D405-H408 IonicContact OD2-CD2 3.97Å; D405-H408 PolarHBondContact OD2-CD2 3.05Å; D405-H408 IonicContact OD2-CG 3.72Å; D405-H408 IonicContact OD2-NE2 2.66Å; H408-R410 PolarHBondContact O-N 3.25Å; H408-F411 PolarHBondContact O-N 2.93Å; H408-H412 PolarHBondContact O-N 3.24Å
409	F	90.7	Very high	89.1	Confident	104 Å²	104	48.9 Å²	48.9	46%	0.456	24%	0.241	S	C	.	.	H	α-helix	trans	-60.4	-46.1	175.9	179.2	-95.8	0	0	0	112	D405 V406 H412 F413	D405-F409 PolarHBondContact O-N 3.13Å; V406-F409 PolarHBondContact O-N 3.49Å; F409-H412 PolarHBondContact O-N 2.68Å; F409-F413 VanDerWaalsContact O-CB 3.31Å; F409-F413 WeakPolarHBondContact O-CB 3.35Å; F409-F413 PolarHBondContact O-N 2.79Å
410	R	91.5	Very high	89.2	Confident	161 Å²	161	51.2 Å²	51.2	61%	0.608	25%	0.249	S	C	*	.	H	α-helix	trans	-61.3	-44.7	176.5	-75.8	176.6	179.9	-178.4	1.6	111.7	V406 S407 H408 F413 F414	V406-R410 HydrophobicContact CG1-CG 4.31Å; V406-R410 WeakPolarHBondContact O-CB 3.44Å; V406-R410 WeakPolarHBondContact O-CG 3.05Å; V406-R410 PolarHBondContact O-N 2.83Å; S407-R410 PolarHBondContact O-N 2.8Å; H408-R410 PolarHBondContact O-N 3.25Å; R410-F413 PolarHBondContact O-N 3.37Å; R410-F414 VanDerWaalsContact O-CD2 3.24Å; R410-F414 WeakPolarHBondContact O-CD2 3.47Å; R410-F414 PolarHBondContact O-N 2.98Å
411	F	92.2	Very high	89.3	Confident	7 Å²	7	52 Å²	52	3%	0.031	25%	0.254	C	S	.	.	H	α-helix	trans	-58.4	-52.7	177.9	-174.2	-94.8	0	0	0	111.1	V275 L278 K279 L347 A350 A351 L354 S407 H408 F413 F414 F415	V275-F411 HydrophobicContact CG1-CD1 3.83Å; V275-F411 HydrophobicContact CG1-CD2 4.47Å; V275-F411 HydrophobicContact CG1-CE1 4Å; V275-F411 HydrophobicContact CG1-CG 4.08Å; V275-F411 HydrophobicContact CG1-CZ 4.4Å; V275-F411 HydrophobicContact CG2-CD1 4.44Å; V275-F411 HydrophobicContact CG2-CE1 3.99Å; L278-F411 HydrophobicContact CB-CE2 4.34Å; L278-F411 HydrophobicContact CB-CZ 4.29Å; K279-F411 HydrophobicContact CD-CB 4.37Å; K279-F411 HydrophobicContact CD-CD2 4.23Å; K279-F411 HydrophobicContact CD-CG 4.46Å; K279-F411 HydrophobicContact CG-CB 4.34Å; K279-F411 HydrophobicContact CG-CD2 3.39Å; K279-F411 HydrophobicContact CG-CE2 3.93Å; K279-F411 HydrophobicContact CG-CG 4.08Å; L347-F411 HydrophobicContact CD2-CE2 3.75Å; L347-F411 HydrophobicContact CD2-CZ 3.83Å; A350-F411 HydrophobicContact CB-CE1 4.3Å; A350-F411 HydrophobicContact CB-CZ 4.37Å; A351-F411 HydrophobicContact CB-CD1 4.11Å; A351-F411 HydrophobicContact CB-CE1 3.85Å; L354-F411 HydrophobicContact CD2-CD1 3.83Å; S407-F411 WeakPolarHBondContact O-CB 3.41Å; S407-F411 PolarHBondContact O-N 2.74Å; H408-F411 PolarHBondContact O-N 2.93Å; F411-F413 VanDerWaalsContact C-N 3.31Å; F411-F413 PolarHBondContact O-N 3.14Å; F411-F414 PolarHBondContact O-N 3.21Å; F411-F415 HydrophobicContact CD1-CD2 4.16Å; F411-F415 AromaticContact CD2-CD2 3.46Å; F411-F415 HydrophobicContact CD2-CD2 3.46Å; F411-F415 VanDerWaalsContact CD2-CD2 3.46Å; F411-F415 AromaticContact CD2-CE2 3.38Å; F411-F415 HydrophobicContact CD2-CE2 3.38Å; F411-F415 HydrophobicContact CE1-CD2 4.18Å; F411-F415 AromaticContact CE2-CD2 3.49Å; F411-F415 HydrophobicContact CE2-CD2 3.49Å; F411-F415 VanDerWaalsContact CE2-CD2 3.49Å; F411-F415 AromaticContact CE2-CE2 3.48Å; F411-F415 HydrophobicContact CE2-CE2 3.48Å; F411-F415 VanDerWaalsContact CE2-CE2 3.48Å; F411-F415 AromaticContact CG-CD2 3.82Å; F411-F415 HydrophobicContact CG-CD2 3.82Å; F411-F415 HydrophobicContact CG-CE2 4.14Å; F411-F415 AromaticContact CZ-CD2 3.87Å; F411-F415 HydrophobicContact CZ-CD2 3.87Å; F411-F415 HydrophobicContact CZ-CE2 4.28Å; F411-F415 WeakPolarHBondContact O-CD2 3.39Å; F411-F415 PolarHBondContact O-N 2.7Å
412	H	91	Very high	89.3	Confident	31 Å²	31	53 Å²	53	14%	0.144	26%	0.258	C	S	.	.	H	α-helix	trans	-59.6	-42.7	175.4	-179.2	-82.6	0	0	0	111.7	A351 G355 C356 H408 F409 F414 S416	A351-H412 PolarHBondContact O-CD2 2.73Å; G355-H412 PolarHBondContact O-CD2 3.31Å; C356-H412 HydrophobicContact CB-CB 4.07Å; C356-H412 PolarHBondContact SG-CE1 2.7Å; C356-H412 PolarHBondContact SG-ND1 3.26Å; H408-H412 PolarHBondContact O-N 3.24Å; F409-H412 PolarHBondContact O-N 2.68Å; H412-F414 PolarHBondContact O-N 3.04Å; H412-S416 WeakPolarHBondContact O-CA 3.41Å; H412-S416 WeakPolarHBondContact O-CB 3.19Å; H412-S416 PolarHBondContact O-N 3.12Å; H412-S416 PolarHBondContact O-OG 3.45Å
413	F	91.2	Very high	89.4	Confident	105 Å²	105	53.9 Å²	53.9	46%	0.461	26%	0.263	S	S	.	.	H	α-helix	trans	-59	-45.3	178.4	178.4	-97.8	0	0	0	111.9	F409 R410 F411 S416 R420	F409-F413 VanDerWaalsContact O-CB 3.31Å; F409-F413 WeakPolarHBondContact O-CB 3.35Å; F409-F413 PolarHBondContact O-N 2.79Å; R410-F413 PolarHBondContact O-N 3.37Å; F411-F413 VanDerWaalsContact C-N 3.31Å; F411-F413 PolarHBondContact O-N 3.14Å; F413-S416 PolarHBondContact O-OG 3.47Å; F413-S416 VanDerWaalsContact O-OG 3.12Å; F413-R420 PolarHBondContact O-NH1 3.17Å; F413-R420 PolarHBondContact O-NH2 3.42Å; F413-R420 VanDerWaalsContact O-NH2 3.07Å
414	F	89.7	Confident	89.7	Confident	93 Å²	93	57.4 Å²	57.4	41%	0.408	28%	0.281	S	S	.	.	H	α-helix	trans	-72.7	-40.6	-178.8	-82.7	-72.9	0	0	0	113.4	R410 F411 H412 R420	R410-F414 VanDerWaalsContact O-CD2 3.24Å; R410-F414 WeakPolarHBondContact O-CD2 3.47Å; R410-F414 PolarHBondContact O-N 2.98Å; F411-F414 PolarHBondContact O-N 3.21Å; H412-F414 PolarHBondContact O-N 3.04Å; F414-R420 VanDerWaalsContact C-NH1 3.3Å; F414-R420 PolarHBondContact O-NH1 3.49Å
415	F	91.2	Very high	90	Very high	10 Å²	10	55.7 Å²	55.7	4%	0.044	27%	0.267	C	S	.	.	H	α-helix	trans	-103.8	-4.5	-170.2	-53.9	-67.4	0	0	0	114.9	F282 L347 H348 A351 F411 K417 I421	F282-F415 HydrophobicContact CD1-CZ 4.05Å; F282-F415 HydrophobicContact CD2-CE1 4.17Å; F282-F415 AromaticContact CD2-CZ 3.77Å; F282-F415 HydrophobicContact CD2-CZ 3.77Å; F282-F415 HydrophobicContact CE1-CZ 4.08Å; F282-F415 AromaticContact CE2-CE1 4Å; F282-F415 HydrophobicContact CE2-CE1 4Å; F282-F415 AromaticContact CE2-CZ 3.81Å; F282-F415 HydrophobicContact CE2-CZ 3.81Å; F282-F415 AromaticContact CG-CZ 3.9Å; F282-F415 HydrophobicContact CG-CZ 3.9Å; F282-F415 HydrophobicContact CZ-CE1 4.4Å; F282-F415 AromaticContact CZ-CZ 3.96Å; F282-F415 HydrophobicContact CZ-CZ 3.96Å; L347-F415 HydrophobicContact CB-CB 4.28Å; L347-F415 HydrophobicContact CB-CD1 3.67Å; L347-F415 HydrophobicContact CB-CD2 4.46Å; L347-F415 HydrophobicContact CB-CE1 4.09Å; L347-F415 HydrophobicContact CB-CG 3.89Å; L347-F415 HydrophobicContact CD1-CD1 3.99Å; L347-F415 HydrophobicContact CD1-CE1 3.54Å; L347-F415 HydrophobicContact CD1-CZ 4.02Å; L347-F415 HydrophobicContact CD2-CE1 4.49Å; L347-F415 HydrophobicContact CD2-CE2 4.43Å; L347-F415 HydrophobicContact CD2-CZ 4.36Å; L347-F415 HydrophobicContact CG-CD1 4.35Å; L347-F415 HydrophobicContact CG-CE1 4.27Å; H348-F415 WeakPolarHBondContact CA-O 3.01Å; H348-F415 PolarHBondContact ND1-O 2.82Å; A351-F415 HydrophobicContact CB-CB 3.77Å; F411-F415 HydrophobicContact CD1-CD2 4.16Å; F411-F415 AromaticContact CD2-CD2 3.46Å; F411-F415 HydrophobicContact CD2-CD2 3.46Å; F411-F415 VanDerWaalsContact CD2-CD2 3.46Å; F411-F415 AromaticContact CD2-CE2 3.38Å; F411-F415 HydrophobicContact CD2-CE2 3.38Å; F411-F415 HydrophobicContact CE1-CD2 4.18Å; F411-F415 AromaticContact CE2-CD2 3.49Å; F411-F415 HydrophobicContact CE2-CD2 3.49Å; F411-F415 VanDerWaalsContact CE2-CD2 3.49Å; F411-F415 AromaticContact CE2-CE2 3.48Å; F411-F415 HydrophobicContact CE2-CE2 3.48Å; F411-F415 VanDerWaalsContact CE2-CE2 3.48Å; F411-F415 AromaticContact CG-CD2 3.82Å; F411-F415 HydrophobicContact CG-CD2 3.82Å; F411-F415 HydrophobicContact CG-CE2 4.14Å; F411-F415 AromaticContact CZ-CD2 3.87Å; F411-F415 HydrophobicContact CZ-CD2 3.87Å; F411-F415 HydrophobicContact CZ-CE2 4.28Å; F411-F415 WeakPolarHBondContact O-CD2 3.39Å; F411-F415 PolarHBondContact O-N 2.7Å; F415-K417 PolarHBondContact O-N 3.15Å; F415-I421 HydrophobicContact CD1-CD1 3.83Å; F415-I421 HydrophobicContact CE1-CD1 3.35Å; F415-I421 HydrophobicContact CZ-CD1 4.37Å
416	S	86.5	Confident	90.3	Very high	37 Å²	37	55 Å²	55	26%	0.259	26%	0.264	S	S	.	.	S	Bend	trans	-54.5	-32.9	172.3	44.5	0	0	0	0	113.9	H348 H412 F413 R420	H348-S416 PolarHBondContact CE1-O 3.31Å; H348-S416 PolarHBondContact ND1-O 3.48Å; H412-S416 WeakPolarHBondContact O-CA 3.41Å; H412-S416 WeakPolarHBondContact O-CB 3.19Å; H412-S416 PolarHBondContact O-N 3.12Å; H412-S416 PolarHBondContact O-OG 3.45Å; F413-S416 PolarHBondContact O-OG 3.47Å; F413-S416 VanDerWaalsContact O-OG 3.12Å; S416-R420 PolarHBondContact OG-NH1 3.13Å; S416-R420 PolarHBondContact OG-NH2 3.36Å
417	K	87.8	Confident	90.6	Very high	143 Å²	143	57.4 Å²	57.4	62%	0.622	27%	0.273	S	S	*	.	S	Bend	trans	-114	112.8	173.2	-66.7	-175.1	178	-179.2	0	108.3	F415 L419 R420	F415-K417 PolarHBondContact O-N 3.15Å; K417-L419 PolarHBondContact O-N 3.2Å; K417-R420 HydrophobicContact CB-CB 4.3Å; K417-R420 VanDerWaalsContact O-CB 3.32Å; K417-R420 WeakPolarHBondContact O-CB 3.42Å; K417-R420 PolarHBondContact O-N 3.22Å; K417-R420 VanDerWaalsContact O-N 3.08Å
418	P	83.3	Confident	90.8	Very high	19 Å²	19	59.3 Å²	59.3	12%	0.123	28%	0.28	C	S	.	.	T	Hydrogen-bonded Turn	trans	-64.2	-28.5	-173.4	23.8	-31.9	0	0	0	112.3	H348 R420 Y477	H348-P418 HydrophobicContact CB-CB 3.99Å; P418-R420 VanDerWaalsContact C-N 3.31Å; P418-R420 PolarHBondContact O-N 3.14Å; P418-Y477 HydrophobicContact CB-CD2 4.24Å; P418-Y477 HydrophobicContact CB-CE1 4.36Å; P418-Y477 HydrophobicContact CB-CE2 3.41Å; P418-Y477 VanDerWaalsContact CB-CE2 3.41Å; P418-Y477 VanDerWaalsContact CB-CZ 3.49Å; P418-Y477 WeakPolarHBondContact CB-OH 2.97Å; P418-Y477 HydrophobicContact CG-CD1 4.07Å; P418-Y477 HydrophobicContact CG-CD2 3.6Å; P418-Y477 HydrophobicContact CG-CE1 3.76Å; P418-Y477 HydrophobicContact CG-CE2 3.21Å; P418-Y477 HydrophobicContact CG-CG 4.02Å
419	L	87.8	Confident	91	Very high	30 Å²	30	59 Å²	59	16%	0.157	28%	0.279	C	S	.	.	H	α-helix	trans	-80	-7.3	-179.6	-56.2	175.3	0	0	0	113.8	K417 L422 N423 L473 Y477	K417-L419 PolarHBondContact O-N 3.2Å; L419-L422 PolarHBondContact O-N 3.49Å; L419-N423 WeakPolarHBondContact O-CB 3.22Å; L419-N423 PolarHBondContact O-N 3.43Å; L419-N423 PolarHBondContact O-ND2 3.11Å; L419-N423 PolarHBondContact O-OD1 3.38Å; L419-L473 HydrophobicContact CD2-CB 3.94Å; L419-L473 HydrophobicContact CD2-CD2 3.74Å; L419-L473 HydrophobicContact CD2-CG 3.71Å; L419-Y477 HydrophobicContact CD2-CD2 4.4Å
420	R	90.7	Very high	91.2	Very high	48 Å²	48	55 Å²	55	18%	0.181	27%	0.266	C	S	.	.	H	α-helix	trans	-62.9	-50.1	-171.8	-175.6	-177.7	-72.7	111.7	-15.7	112.1	F413 F414 S416 K417 P418 L422 N423 I424	F413-R420 PolarHBondContact O-NH1 3.17Å; F413-R420 PolarHBondContact O-NH2 3.42Å; F413-R420 VanDerWaalsContact O-NH2 3.07Å; F414-R420 VanDerWaalsContact C-NH1 3.3Å; F414-R420 PolarHBondContact O-NH1 3.49Å; S416-R420 PolarHBondContact OG-NH1 3.13Å; S416-R420 PolarHBondContact OG-NH2 3.36Å; K417-R420 HydrophobicContact CB-CB 4.3Å; K417-R420 VanDerWaalsContact O-CB 3.32Å; K417-R420 WeakPolarHBondContact O-CB 3.42Å; K417-R420 PolarHBondContact O-N 3.22Å; K417-R420 VanDerWaalsContact O-N 3.08Å; P418-R420 VanDerWaalsContact C-N 3.31Å; P418-R420 PolarHBondContact O-N 3.14Å; R420-L422 VanDerWaalsContact C-N 3.31Å; R420-L422 PolarHBondContact O-N 3.09Å; R420-N423 PolarHBondContact O-N 3.23Å; R420-I424 HydrophobicContact CG-CD1 4.06Å; R420-I424 WeakPolarHBondContact O-CG1 3.1Å; R420-I424 PolarHBondContact O-N 3.04Å
421	I	90.4	Very high	91.4	Very high	18 Å²	18	50 Å²	50	9%	0.092	26%	0.26	C	S	.	.	H	α-helix	trans	-62.3	-44.7	-179.4	-66.5	174.2	0	0	0	110.1	F282 L339 F415 N423 I424 L425	F282-I421 HydrophobicContact CE2-CD1 4.25Å; L339-I421 HydrophobicContact CD1-CG2 4.24Å; F415-I421 HydrophobicContact CD1-CD1 3.83Å; F415-I421 HydrophobicContact CE1-CD1 3.35Å; F415-I421 HydrophobicContact CZ-CD1 4.37Å; I421-N423 VanDerWaalsContact C-N 3.32Å; I421-N423 PolarHBondContact O-N 3.44Å; I421-I424 WeakPolarHBondContact O-CB 3.46Å; I421-I424 PolarHBondContact O-N 2.92Å; I421-I424 VanDerWaalsContact O-N 3.13Å; I421-L425 HydrophobicContact CG2-CD1 4.17Å; I421-L425 HydrophobicContact CG2-CG 4.46Å; I421-L425 WeakPolarHBondContact O-CG 3.32Å; I421-L425 PolarHBondContact O-N 2.85Å
422	L	90.6	Very high	91.5	Very high	23 Å²	23	50.3 Å²	50.3	12%	0.12	26%	0.262	C	S	.	.	H	α-helix	trans	-62.2	-40.1	178.7	-170.2	61.3	0	0	0	112.2	L419 R420 L425 L426 L466 R470 L473	L419-L422 PolarHBondContact O-N 3.49Å; R420-L422 VanDerWaalsContact C-N 3.31Å; R420-L422 PolarHBondContact O-N 3.09Å; L422-L425 PolarHBondContact O-N 2.82Å; L422-L426 WeakPolarHBondContact O-CB 3.26Å; L422-L426 PolarHBondContact O-N 3.3Å; L422-L466 HydrophobicContact CD1-CD2 3.59Å; L422-R470 HydrophobicContact CD2-CB 3.58Å; L422-R470 HydrophobicContact CD2-CG 4.31Å; L422-R470 HydrophobicContact CG-CB 3.99Å; L422-L473 HydrophobicContact CD2-CD2 4.39Å
423	N	92.7	Very high	91.7	Very high	65 Å²	65	49.5 Å²	49.5	35%	0.348	26%	0.259	S	S	.	.	H	α-helix	trans	-65.5	-38.3	173.9	-68.7	-20.2	0	0	0	112.2	L419 R420 I421 L426 L427 R470	L419-N423 WeakPolarHBondContact O-CB 3.22Å; L419-N423 PolarHBondContact O-N 3.43Å; L419-N423 PolarHBondContact O-ND2 3.11Å; L419-N423 PolarHBondContact O-OD1 3.38Å; R420-N423 PolarHBondContact O-N 3.23Å; I421-N423 VanDerWaalsContact C-N 3.32Å; I421-N423 PolarHBondContact O-N 3.44Å; N423-L426 PolarHBondContact O-N 3.11Å; N423-L427 WeakPolarHBondContact O-CB 3.31Å; N423-L427 PolarHBondContact O-N 3.11Å; N423-R470 WeakPolarHBondContact OD1-CD 3.41Å; N423-R470 PolarHBondContact OD1-NE 3.23Å
424	I	92.8	Very high	91.9	Very high	88 Å²	88	49.2 Å²	49.2	45%	0.451	27%	0.265	S	S	.	.	H	α-helix	trans	-63.8	-45.6	175.9	-68.5	164.4	0	0	0	110.1	R420 I421 L426 L427 L428	R420-I424 HydrophobicContact CG-CD1 4.06Å; R420-I424 WeakPolarHBondContact O-CG1 3.1Å; R420-I424 PolarHBondContact O-N 3.04Å; I421-I424 WeakPolarHBondContact O-CB 3.46Å; I421-I424 PolarHBondContact O-N 2.92Å; I421-I424 VanDerWaalsContact O-N 3.13Å; I424-L426 VanDerWaalsContact C-N 3.35Å; I424-L427 PolarHBondContact O-N 3.35Å; I424-L428 WeakPolarHBondContact O-CB 3.43Å; I424-L428 PolarHBondContact O-N 2.84Å
425	L	93.2	Very high	92.1	Very high	14 Å²	14	49.4 Å²	49.4	7%	0.073	26%	0.264	C	S	.	.	H	α-helix	trans	-63.1	-41.5	176.7	-66.9	175.2	0	0	0	111.6	V332 M335 I421 L422 L428 E429 L466	V332-L425 HydrophobicContact CG2-CD2 4.42Å; M335-L425 HydrophobicContact CB-CD1 3.91Å; M335-L425 HydrophobicContact CB-CD2 3.89Å; M335-L425 HydrophobicContact CE-CD2 4.14Å; M335-L425 HydrophobicContact CG-CD2 4.11Å; I421-L425 HydrophobicContact CG2-CD1 4.17Å; I421-L425 HydrophobicContact CG2-CG 4.46Å; I421-L425 WeakPolarHBondContact O-CG 3.32Å; I421-L425 PolarHBondContact O-N 2.85Å; L422-L425 PolarHBondContact O-N 2.82Å; L425-L428 PolarHBondContact O-N 2.93Å; L425-E429 VanDerWaalsContact O-CB 3.31Å; L425-E429 WeakPolarHBondContact O-CB 3.23Å; L425-E429 PolarHBondContact O-N 2.75Å; L425-L466 HydrophobicContact CB-CD1 4.25Å; L425-L466 HydrophobicContact CB-CD2 3.96Å; L425-L466 HydrophobicContact CD1-CD2 4.21Å
426	L	93.9	Very high	92.2	Very high	34 Å²	34	48.9 Å²	48.9	18%	0.178	26%	0.262	C	S	.	.	H	α-helix	trans	-65	-40.4	177	-170.1	72.7	0	0	0	112.1	L422 N423 I424 G430 F463 L466 L467	L422-L426 WeakPolarHBondContact O-CB 3.26Å; L422-L426 PolarHBondContact O-N 3.3Å; N423-L426 PolarHBondContact O-N 3.11Å; I424-L426 VanDerWaalsContact C-N 3.35Å; L426-G430 WeakPolarHBondContact O-CA 3.14Å; L426-G430 PolarHBondContact O-N 3.38Å; L426-F463 HydrophobicContact CD1-CD2 3.8Å; L426-F463 HydrophobicContact CD1-CE2 3.33Å; L426-F463 HydrophobicContact CD1-CZ 3.79Å; L426-F463 HydrophobicContact CG-CE2 4.01Å; L426-F463 HydrophobicContact CG-CZ 4.5Å; L426-L466 HydrophobicContact CD1-CB 4.03Å; L426-L467 HydrophobicContact CD1-CB 4.42Å
427	L	95.2	Very high	92.6	Very high	137 Å²	137	50.1 Å²	50.1	72%	0.717	27%	0.265	S	S	*	.	H	α-helix	trans	-64.2	-45.9	175.3	-174.9	81.3	0	0	0	110.8	N423 I424 G430 A431	N423-L427 WeakPolarHBondContact O-CB 3.31Å; N423-L427 PolarHBondContact O-N 3.11Å; I424-L427 PolarHBondContact O-N 3.35Å; L427-G430 PolarHBondContact O-N 3.25Å; L427-A431 WeakPolarHBondContact O-CB 3.32Å; L427-A431 PolarHBondContact O-N 3.24Å
428	L	94.1	Very high	92.9	Very high	72 Å²	72	50.6 Å²	50.6	38%	0.377	26%	0.264	S	S	.	.	H	α-helix	trans	-62.5	-49.2	179.8	-177.8	63.2	0	0	0	111.3	I328 V332 I424 L425 A431 V432	I328-L428 HydrophobicContact CG2-CD1 3.97Å; I328-L428 HydrophobicContact CG2-CD2 3.91Å; I328-L428 HydrophobicContact CG2-CG 3.75Å; V332-L428 HydrophobicContact CG2-CD2 3.94Å; V332-L428 HydrophobicContact CG2-CG 4.37Å; I424-L428 WeakPolarHBondContact O-CB 3.43Å; I424-L428 PolarHBondContact O-N 2.84Å; L425-L428 PolarHBondContact O-N 2.93Å; L428-A431 PolarHBondContact O-N 3.27Å; L428-V432 WeakPolarHBondContact O-CG2 3.27Å; L428-V432 PolarHBondContact O-N 2.74Å
429	E	93.9	Very high	93.3	Very high	0 Å²	0	50.5 Å²	50.5	0%	0	26%	0.264	C	S	.	.	H	α-helix	trans	-65.8	-41.4	178.1	-169.6	63.5	-161.4	0	0	111.6	V332 L425 A431 V432 I433 N459 F463 L466	V332-E429 HydrophobicContact CG1-CB 4.34Å; V332-E429 HydrophobicContact CG1-CG 4.48Å; V332-E429 WeakPolarHBondContact CG1-OE2 3.39Å; L425-E429 VanDerWaalsContact O-CB 3.31Å; L425-E429 WeakPolarHBondContact O-CB 3.23Å; L425-E429 PolarHBondContact O-N 2.75Å; E429-A431 PolarHBondContact O-N 3.13Å; E429-V432 WeakPolarHBondContact O-CB 3.46Å; E429-V432 PolarHBondContact O-N 2.9Å; E429-I433 HydrophobicContact CG-CD1 4.17Å; E429-I433 WeakPolarHBondContact O-CG1 3.44Å; E429-I433 PolarHBondContact O-N 2.97Å; E429-N459 WeakPolarHBondContact OE1-CA 3.46Å; E429-N459 VanDerWaalsContact OE1-CB 3.28Å; E429-N459 WeakPolarHBondContact OE1-CB 3.48Å; E429-F463 HydrophobicContact CB-CD2 4.21Å; E429-F463 HydrophobicContact CG-CB 3.96Å; E429-F463 HydrophobicContact CG-CD2 3.95Å; E429-F463 HydrophobicContact CG-CG 4.48Å; E429-L466 HydrophobicContact CB-CD1 4.1Å; E429-L466 HydrophobicContact CG-CD1 4.36Å
430	G	95.2	Very high	93.5	Very high	19 Å²	19	51.3 Å²	51.3	20%	0.196	27%	0.268	C	S	.	.	H	α-helix	trans	-60.8	-42.9	175.2	0	0	0	0	0	112.3	L426 L427 V432 I433 V434	L426-G430 WeakPolarHBondContact O-CA 3.14Å; L426-G430 PolarHBondContact O-N 3.38Å; L427-G430 PolarHBondContact O-N 3.25Å; G430-V432 VanDerWaalsContact C-N 3.34Å; G430-V432 PolarHBondContact O-N 2.65Å; G430-I433 PolarHBondContact O-N 2.96Å; G430-V434 WeakPolarHBondContact O-CB 3.18Å; G430-V434 VanDerWaalsContact O-CG2 3.28Å; G430-V434 WeakPolarHBondContact O-CG2 3.22Å; G430-V434 PolarHBondContact O-N 3.5Å
431	A	95.4	Very high	93.5	Very high	58 Å²	58	57.1 Å²	57.1	48%	0.479	30%	0.299	S	S	.	.	H	α-helix	trans	-63	-41	175.2	0	0	0	0	0	111.8	L427 L428 E429 V434 Y435	L427-A431 WeakPolarHBondContact O-CB 3.32Å; L427-A431 PolarHBondContact O-N 3.24Å; L428-A431 PolarHBondContact O-N 3.27Å; E429-A431 PolarHBondContact O-N 3.13Å; A431-V434 PolarHBondContact O-N 2.74Å; A431-Y435 WeakPolarHBondContact O-CB 3.49Å; A431-Y435 PolarHBondContact O-N 2.88Å
432	V	94.3	Very high	93.5	Very high	13 Å²	13	59.4 Å²	59.4	8%	0.079	32%	0.317	C	S	.	.	H	α-helix	trans	-64.4	-39.9	176.2	163.3	0	0	0	0	112	L325 I328 L428 E429 G430 Q436	L325-V432 HydrophobicContact CD1-CG1 3.47Å; L325-V432 VanDerWaalsContact CD1-CG1 3.47Å; I328-V432 HydrophobicContact CB-CG2 4.29Å; I328-V432 HydrophobicContact CD1-CG2 4.26Å; I328-V432 HydrophobicContact CG2-CG2 3.65Å; L428-V432 WeakPolarHBondContact O-CG2 3.27Å; L428-V432 PolarHBondContact O-N 2.74Å; E429-V432 WeakPolarHBondContact O-CB 3.46Å; E429-V432 PolarHBondContact O-N 2.9Å; G430-V432 VanDerWaalsContact C-N 3.34Å; G430-V432 PolarHBondContact O-N 2.65Å; V432-Q436 WeakPolarHBondContact O-CB 3.49Å; V432-Q436 WeakPolarHBondContact O-CG 3.05Å; V432-Q436 PolarHBondContact O-N 2.76Å; V432-Q436 PolarHBondContact O-NE2 3.29Å
433	I	95.2	Very high	93.4	Very high	14 Å²	14	59.2 Å²	59.2	7%	0.072	32%	0.318	C	S	.	.	H	α-helix	trans	-67.5	-46	175.4	-75	168.7	0	0	0	111.1	E429 G430 Y435 Q436 L437 L456 N459 Y460 F463	E429-I433 HydrophobicContact CG-CD1 4.17Å; E429-I433 WeakPolarHBondContact O-CG1 3.44Å; E429-I433 PolarHBondContact O-N 2.97Å; G430-I433 PolarHBondContact O-N 2.96Å; I433-Y435 VanDerWaalsContact C-N 3.29Å; I433-Y435 PolarHBondContact O-N 2.72Å; I433-Q436 PolarHBondContact O-N 2.91Å; I433-L437 HydrophobicContact CG2-CD1 4Å; I433-L437 HydrophobicContact CG2-CG 4.48Å; I433-L437 WeakPolarHBondContact O-CB 3.43Å; I433-L437 WeakPolarHBondContact O-CG 3.19Å; I433-L437 PolarHBondContact O-N 2.81Å; I433-L456 HydrophobicContact CG1-CD1 4.31Å; I433-L456 HydrophobicContact CG2-CD1 4.16Å; I433-N459 HydrophobicContact CG1-CB 4.28Å; I433-Y460 HydrophobicContact CD1-CD1 3.95Å; I433-Y460 HydrophobicContact CD1-CE1 4.3Å; I433-Y460 HydrophobicContact CG1-CD1 4.46Å; I433-Y460 HydrophobicContact CG1-CE1 4.49Å; I433-Y460 HydrophobicContact CG2-CD1 4.36Å; I433-Y460 HydrophobicContact CG2-CE1 3.64Å; I433-F463 HydrophobicContact CD1-CB 3.56Å; I433-F463 HydrophobicContact CD1-CD1 4.48Å; I433-F463 HydrophobicContact CD1-CD2 3.89Å; I433-F463 HydrophobicContact CD1-CG 3.74Å
434	V	95.5	Very high	93.1	Very high	98 Å²	98	65.2 Å²	65.2	59%	0.594	34%	0.344	S	S	*	.	H	α-helix	trans	-60.6	-42.4	177.2	169.8	0	0	0	0	110.5	G430 A431 L437 Y438	G430-V434 WeakPolarHBondContact O-CB 3.18Å; G430-V434 VanDerWaalsContact O-CG2 3.28Å; G430-V434 WeakPolarHBondContact O-CG2 3.22Å; G430-V434 PolarHBondContact O-N 3.5Å; A431-V434 PolarHBondContact O-N 2.74Å; V434-L437 PolarHBondContact O-N 3.4Å; V434-Y438 WeakPolarHBondContact O-CB 3.32Å; V434-Y438 PolarHBondContact O-N 3.23Å
435	Y	93.8	Very high	92.8	Very high	97 Å²	97	65.6 Å²	65.6	38%	0.38	34%	0.342	S	S	.	.	H	α-helix	trans	-62.3	-44	174.6	176.6	-96.4	0	0	0	112.6	E321 A431 I433 Y438 S439	E321-Y435 PolarHBondContact OE1-OH 3.19Å; E321-Y435 PolarHBondContact OE2-OH 2.84Å; A431-Y435 WeakPolarHBondContact O-CB 3.49Å; A431-Y435 PolarHBondContact O-N 2.88Å; I433-Y435 VanDerWaalsContact C-N 3.29Å; I433-Y435 PolarHBondContact O-N 2.72Å; Y435-Y438 PolarHBondContact O-N 2.7Å; Y435-S439 WeakPolarHBondContact CE1-OG 3.27Å; Y435-S439 WeakPolarHBondContact O-CB 3.48Å; Y435-S439 PolarHBondContact O-N 3Å; Y435-S439 PolarHBondContact O-OG 3.4Å
436	Q	93.8	Very high	92.5	Very high	0 Å²	0	68.3 Å²	68.3	0%	0	35%	0.351	C	S	.	.	H	α-helix	trans	-63.8	-40.6	176.8	-82.6	165.7	85.7	0	0	112	L325 V432 I433 S439 L440 L452 L456 N459	L325-Q436 HydrophobicContact CD1-CG 4.07Å; L325-Q436 HydrophobicContact CD2-CG 4.09Å; V432-Q436 WeakPolarHBondContact O-CB 3.49Å; V432-Q436 WeakPolarHBondContact O-CG 3.05Å; V432-Q436 PolarHBondContact O-N 2.76Å; V432-Q436 PolarHBondContact O-NE2 3.29Å; I433-Q436 PolarHBondContact O-N 2.91Å; Q436-S439 PolarHBondContact O-N 3.36Å; Q436-L440 VanDerWaalsContact O-CB 3.22Å; Q436-L440 WeakPolarHBondContact O-CB 3.5Å; Q436-L440 PolarHBondContact O-N 3.41Å; Q436-L452 HydrophobicContact CG-CD2 4.18Å; Q436-L456 HydrophobicContact CB-CD1 3.95Å; Q436-N459 PolarHBondContact NE2-ND2 2.62Å; Q436-N459 PolarHBondContact OE1-ND2 3.45Å
437	L	94.5	Very high	92.2	Very high	63 Å²	63	67.2 Å²	67.2	33%	0.33	35%	0.345	S	S	.	.	H	α-helix	trans	-64.7	-45.1	176.1	-76.8	172	0	0	0	111.6	I433 V434 S439 L440 M441 L456	I433-L437 HydrophobicContact CG2-CD1 4Å; I433-L437 HydrophobicContact CG2-CG 4.48Å; I433-L437 WeakPolarHBondContact O-CB 3.43Å; I433-L437 WeakPolarHBondContact O-CG 3.19Å; I433-L437 PolarHBondContact O-N 2.81Å; V434-L437 PolarHBondContact O-N 3.4Å; L437-S439 VanDerWaalsContact C-N 3.35Å; L437-S439 PolarHBondContact O-N 2.9Å; L437-L440 WeakPolarHBondContact O-CB 3.47Å; L437-L440 PolarHBondContact O-N 3.48Å; L437-M441 WeakPolarHBondContact O-CG 3.47Å; L437-M441 PolarHBondContact O-N 3.29Å; L437-L456 HydrophobicContact CD2-CD2 3.79Å; L437-L456 HydrophobicContact CG-CD2 4.35Å
438	Y	93.8	Very high	91.8	Very high	153 Å²	153	61.9 Å²	61.9	60%	0.6	32%	0.317	S	S	*	.	H	α-helix	trans	-59.1	-46.1	173.4	172.1	-97.4	0	0	0	111.9	V434 Y435 L440 M441 S442	V434-Y438 WeakPolarHBondContact O-CB 3.32Å; V434-Y438 PolarHBondContact O-N 3.23Å; Y435-Y438 PolarHBondContact O-N 2.7Å; Y438-L440 VanDerWaalsContact C-N 3.29Å; Y438-L440 PolarHBondContact O-N 3.28Å; Y438-M441 PolarHBondContact O-N 2.85Å; Y438-S442 WeakPolarHBondContact O-CB 3.33Å; Y438-S442 PolarHBondContact O-N 2.88Å; Y438-S442 PolarHBondContact O-OG 3.48Å
439	S	91.7	Very high	91.7	Very high	17 Å²	17	60.9 Å²	60.9	12%	0.119	31%	0.314	C	S	.	.	H	α-helix	trans	-63.8	-36.5	177.4	-57.5	0	0	0	0	111.6	Y435 Q436 L437 S442 S443	Y435-S439 WeakPolarHBondContact CE1-OG 3.27Å; Y435-S439 WeakPolarHBondContact O-CB 3.48Å; Y435-S439 PolarHBondContact O-N 3Å; Y435-S439 PolarHBondContact O-OG 3.4Å; Q436-S439 PolarHBondContact O-N 3.36Å; L437-S439 VanDerWaalsContact C-N 3.35Å; L437-S439 PolarHBondContact O-N 2.9Å; S439-S442 CarbonylContact O-C 3.6Å; S439-S442 PolarHBondContact O-N 2.98Å; S439-S443 VanDerWaalsContact O-CB 3.22Å; S439-S443 WeakPolarHBondContact O-CB 3.45Å; S439-S443 PolarHBondContact O-N 2.94Å
440	L	92.1	Very high	91.5	Very high	47 Å²	47	64.5 Å²	64.5	25%	0.246	33%	0.332	C	S	.	.	H	α-helix	trans	-67.5	-43.3	177.7	-176.8	69.2	0	0	0	111	Q436 L437 Y438 S442 S443 T449 L452 L456	Q436-L440 VanDerWaalsContact O-CB 3.22Å; Q436-L440 WeakPolarHBondContact O-CB 3.5Å; Q436-L440 PolarHBondContact O-N 3.41Å; L437-L440 WeakPolarHBondContact O-CB 3.47Å; L437-L440 PolarHBondContact O-N 3.48Å; Y438-L440 VanDerWaalsContact C-N 3.29Å; Y438-L440 PolarHBondContact O-N 3.28Å; L440-S442 VanDerWaalsContact C-N 3.28Å; L440-S442 PolarHBondContact O-N 3.3Å; L440-S443 WeakPolarHBondContact O-CB 3.5Å; L440-S443 PolarHBondContact O-N 3.46Å; L440-T449 HydrophobicContact CD1-CG2 3.7Å; L440-L452 HydrophobicContact CB-CB 4.47Å; L440-L452 HydrophobicContact CB-CD1 4.3Å; L440-L452 HydrophobicContact CD1-CB 3.94Å; L440-L456 HydrophobicContact CD2-CD2 4.44Å
441	M	91.3	Very high	91.3	Very high	169 Å²	169	63.6 Å²	63.6	83%	0.833	32%	0.323	S	S	*	.	H	α-helix	trans	-65.1	-32.8	174.7	-72.7	179.3	57.4	0	0	112.6	L437 Y438 S443	L437-M441 WeakPolarHBondContact O-CG 3.47Å; L437-M441 PolarHBondContact O-N 3.29Å; Y438-M441 PolarHBondContact O-N 2.85Å; M441-S443 VanDerWaalsContact C-N 3.33Å
442	S	90.3	Very high	91.1	Very high	67 Å²	67	61.2 Å²	61.2	47%	0.469	30%	0.302	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85.9	-4.9	178.7	-51.3	0	0	0	0	113.1	Y438 S439 L440 E444	Y438-S442 WeakPolarHBondContact O-CB 3.33Å; Y438-S442 PolarHBondContact O-N 2.88Å; Y438-S442 PolarHBondContact O-OG 3.48Å; S439-S442 CarbonylContact O-C 3.6Å; S439-S442 PolarHBondContact O-N 2.98Å; L440-S442 VanDerWaalsContact C-N 3.28Å; L440-S442 PolarHBondContact O-N 3.3Å; S442-E444 PolarHBondContact O-N 3Å
443	S	88.4	Confident	91	Very high	19 Å²	19	62.9 Å²	62.9	13%	0.133	32%	0.317	C	S	.	.			trans	-86.1	109.3	-173.1	172.2	0	0	0	0	111.4	S439 L440 M441 K445 Q448 T449	S439-S443 VanDerWaalsContact O-CB 3.22Å; S439-S443 WeakPolarHBondContact O-CB 3.45Å; S439-S443 PolarHBondContact O-N 2.94Å; L440-S443 WeakPolarHBondContact O-CB 3.5Å; L440-S443 PolarHBondContact O-N 3.46Å; M441-S443 VanDerWaalsContact C-N 3.33Å; S443-K445 PolarHBondContact OG-O 3.22Å; S443-Q448 WeakPolarHBondContact OG-CB 3.01Å; S443-T449 PolarHBondContact OG-N 3.02Å; S443-T449 PolarHBondContact OG-OG1 3.31Å
444	E	86.1	Confident	90.8	Very high	191 Å²	191	65.3 Å²	65.3	89%	0.893	33%	0.33	S	S	*	.			trans	-83.4	-22.6	173.9	-61.7	177.5	175.9	0	0	112.6	S442	S442-E444 PolarHBondContact O-N 3Å
445	K	87.2	Confident	90.7	Very high	95 Å²	95	61.1 Å²	61.1	41%	0.413	30%	0.304	S	S	.	.	S	Bend	trans	-91.6	127.3	-171.9	-57.2	179.4	-169.3	164.7	0	111.3	S443 H447 Q448 T449	S443-K445 PolarHBondContact OG-O 3.22Å; K445-H447 VanDerWaalsContact C-N 3.27Å; K445-H447 VanDerWaalsContact CB-CE1 3.45Å; K445-H447 WeakPolarHBondContact CB-CE1 3.38Å; K445-H447 PolarHBondContact O-N 3.44Å; K445-H447 VanDerWaalsContact O-N 3.1Å; K445-Q448 HydrophobicContact CB-CB 4.3Å; K445-Q448 HydrophobicContact CB-CG 4.14Å; K445-Q448 WeakPolarHBondContact O-CB 3.46Å; K445-Q448 PolarHBondContact O-N 3.46Å; K445-T449 PolarHBondContact O-N 2.9Å; K445-T449 VanDerWaalsContact O-N 3.08Å; K445-T449 PolarHBondContact O-OG1 3.35Å
446	W	86.9	Confident	90.6	Very high	72 Å²	72	57 Å²	57	27%	0.273	29%	0.289	S	S	.	.	H	α-helix	trans	-49.1	-43.6	-178.8	74	-90.7	0	0	0	114.2	I97 K101 W105 T449 I450	I97-W446 HydrophobicContact CG2-CH2 4.05Å; I97-W446 HydrophobicContact CG2-CZ3 4.24Å; K101-W446 HydrophobicContact CB-CZ2 4.17Å; W105-W446 AromaticContact CH2-CD1 3.24Å; W105-W446 HydrophobicContact CH2-CG 4.36Å; W105-W446 AromaticContact CH2-NE1 3.14Å; W105-W446 AromaticContact CZ3-CD1 3.55Å; W105-W446 AromaticContact CZ3-CE2 3.95Å; W105-W446 HydrophobicContact CZ3-CG 4.35Å; W105-W446 AromaticContact CZ3-NE1 3.26Å; W105-W446 VanDerWaalsContact CZ3-NE1 3.26Å; W446-T449 PolarHBondContact O-N 3.34Å; W446-I450 HydrophobicContact CE3-CD1 3.63Å; W446-I450 HydrophobicContact CZ3-CD1 3.89Å; W446-I450 WeakPolarHBondContact O-CG1 3.25Å; W446-I450 PolarHBondContact O-N 2.71Å
447	H	86.4	Confident	90.5	Very high	11 Å²	11	64 Å²	64	5%	0.051	32%	0.319	C	S	.	.	H	α-helix	trans	-70.3	-37.7	-176.4	52.4	-82	0	0	0	111.3	I97 N98 K101 K445 T449 S451	I97-H447 HydrophobicContact CG2-CB 4.07Å; N98-H447 PolarHBondContact OD1-CD2 2.79Å; N98-H447 VanDerWaalsContact OD1-CD2 3.28Å; K101-H447 PolarHBondContact NZ-CE1 2.76Å; K101-H447 PolarHBondContact NZ-NE2 2.83Å; K445-H447 VanDerWaalsContact C-N 3.27Å; K445-H447 VanDerWaalsContact CB-CE1 3.45Å; K445-H447 WeakPolarHBondContact CB-CE1 3.38Å; K445-H447 PolarHBondContact O-N 3.44Å; K445-H447 VanDerWaalsContact O-N 3.1Å; H447-T449 VanDerWaalsContact C-N 3.34Å; H447-S451 WeakPolarHBondContact O-CB 3.47Å; H447-S451 PolarHBondContact O-N 2.69Å; H447-S451 PolarHBondContact O-OG 2.88Å
448	Q	88.8	Confident	90.2	Very high	25 Å²	25	61.6 Å²	61.6	12%	0.117	31%	0.307	C	S	.	.	H	α-helix	trans	-65.4	-41.5	175.5	-70	176.5	-26.5	0	0	110.3	W318 S443 K445 S451 L452	W318-Q448 HydrophobicContact CD2-CG 4.28Å; W318-Q448 HydrophobicContact CE3-CG 4.03Å; W318-Q448 HydrophobicContact CH2-CB 3.65Å; W318-Q448 HydrophobicContact CH2-CG 3.8Å; W318-Q448 HydrophobicContact CZ2-CB 4.19Å; W318-Q448 HydrophobicContact CZ2-CG 4.15Å; W318-Q448 HydrophobicContact CZ3-CB 3.99Å; W318-Q448 HydrophobicContact CZ3-CG 3.77Å; S443-Q448 WeakPolarHBondContact OG-CB 3.01Å; K445-Q448 HydrophobicContact CB-CB 4.3Å; K445-Q448 HydrophobicContact CB-CG 4.14Å; K445-Q448 WeakPolarHBondContact O-CB 3.46Å; K445-Q448 PolarHBondContact O-N 3.46Å; Q448-S451 WeakPolarHBondContact O-CB 3.5Å; Q448-S451 PolarHBondContact O-N 3.32Å; Q448-L452 WeakPolarHBondContact O-CB 3.3Å; Q448-L452 WeakPolarHBondContact O-CG 3.44Å; Q448-L452 PolarHBondContact O-N 2.82Å
449	T	90.7	Very high	90.1	Very high	51 Å²	51	54.3 Å²	54.3	31%	0.313	28%	0.279	S	S	.	.	H	α-helix	trans	-61.8	-49.6	176.8	-52	0	0	0	0	111.9	L440 S443 K445 W446 H447 S451 L452 A453	L440-T449 HydrophobicContact CD1-CG2 3.7Å; S443-T449 PolarHBondContact OG-N 3.02Å; S443-T449 PolarHBondContact OG-OG1 3.31Å; K445-T449 PolarHBondContact O-N 2.9Å; K445-T449 VanDerWaalsContact O-N 3.08Å; K445-T449 PolarHBondContact O-OG1 3.35Å; W446-T449 PolarHBondContact O-N 3.34Å; H447-T449 VanDerWaalsContact C-N 3.34Å; T449-S451 VanDerWaalsContact C-N 3.33Å; T449-S451 PolarHBondContact O-N 3.32Å; T449-L452 PolarHBondContact O-N 3.4Å; T449-A453 VanDerWaalsContact O-CB 3.31Å; T449-A453 WeakPolarHBondContact O-CB 3.43Å; T449-A453 PolarHBondContact O-N 2.69Å
450	I	89.8	Confident	90.2	Very high	75 Å²	75	58.2 Å²	58.2	39%	0.385	29%	0.292	S	S	.	.	H	α-helix	trans	-62.3	-43.2	176.9	-66.8	178.6	0	0	0	111	W446 A453 L454	W446-I450 HydrophobicContact CE3-CD1 3.63Å; W446-I450 HydrophobicContact CZ3-CD1 3.89Å; W446-I450 WeakPolarHBondContact O-CG1 3.25Å; W446-I450 PolarHBondContact O-N 2.71Å; I450-A453 PolarHBondContact O-N 3.05Å; I450-L454 HydrophobicContact CG2-CD1 3.95Å; I450-L454 HydrophobicContact CG2-CG 4.41Å; I450-L454 WeakPolarHBondContact O-CG 3.47Å; I450-L454 PolarHBondContact O-N 2.98Å
451	S	91	Very high	90.1	Very high	0 Å²	0	60.1 Å²	60.1	0%	0	30%	0.296	C	S	.	.	H	α-helix	trans	-59	-50.1	179.8	-65.1	0	0	0	0	112.3	V94 N98 H447 Q448 T449 I455	V94-S451 VanDerWaalsContact CG1-OG 3.31Å; V94-S451 WeakPolarHBondContact CG1-OG 3.3Å; N98-S451 PolarHBondContact ND2-OG 3.32Å; N98-S451 PolarHBondContact OD1-OG 3.19Å; N98-S451 VanDerWaalsContact OD1-OG 3.13Å; H447-S451 WeakPolarHBondContact O-CB 3.47Å; H447-S451 PolarHBondContact O-N 2.69Å; H447-S451 PolarHBondContact O-OG 2.88Å; Q448-S451 WeakPolarHBondContact O-CB 3.5Å; Q448-S451 PolarHBondContact O-N 3.32Å; T449-S451 VanDerWaalsContact C-N 3.33Å; T449-S451 PolarHBondContact O-N 3.32Å; S451-I455 WeakPolarHBondContact O-CG1 3.28Å; S451-I455 PolarHBondContact O-N 3.16Å; S451-I455 VanDerWaalsContact O-N 3.17Å
452	L	91.9	Very high	90	Very high	8 Å²	8	52.3 Å²	52.3	4%	0.042	26%	0.258	C	S	.	.	H	α-helix	trans	-65.6	-43.2	178.2	-73.7	165.4	0	0	0	111.1	W318 Q436 L440 Q448 T449 L454 I455 L456	W318-L452 HydrophobicContact CH2-CD1 3.74Å; W318-L452 HydrophobicContact CH2-CD2 4.06Å; W318-L452 HydrophobicContact CH2-CG 3.62Å; W318-L452 HydrophobicContact CZ2-CG 4.29Å; W318-L452 HydrophobicContact CZ3-CD1 4.34Å; Q436-L452 HydrophobicContact CG-CD2 4.18Å; L440-L452 HydrophobicContact CB-CB 4.47Å; L440-L452 HydrophobicContact CB-CD1 4.3Å; L440-L452 HydrophobicContact CD1-CB 3.94Å; Q448-L452 WeakPolarHBondContact O-CB 3.3Å; Q448-L452 WeakPolarHBondContact O-CG 3.44Å; Q448-L452 PolarHBondContact O-N 2.82Å; T449-L452 PolarHBondContact O-N 3.4Å; L452-L454 VanDerWaalsContact C-N 3.34Å; L452-L454 PolarHBondContact O-N 3.24Å; L452-I455 PolarHBondContact O-N 3.28Å; L452-L456 WeakPolarHBondContact O-CB 3.5Å; L452-L456 PolarHBondContact O-N 2.95Å
453	A	92.1	Very high	90.2	Very high	48 Å²	48	51.9 Å²	51.9	40%	0.397	25%	0.248	S	C	.	.	H	α-helix	trans	-58.8	-44	179.3	0	0	0	0	0	112.4	T449 I450 F457	T449-A453 VanDerWaalsContact O-CB 3.31Å; T449-A453 WeakPolarHBondContact O-CB 3.43Å; T449-A453 PolarHBondContact O-N 2.69Å; I450-A453 PolarHBondContact O-N 3.05Å; A453-F457 PolarHBondContact O-N 3.04Å; A453-F457 VanDerWaalsContact O-N 3.16Å
454	L	91.5	Very high	90.4	Very high	66 Å²	66	56.9 Å²	56.9	35%	0.346	27%	0.268	S	S	.	.	H	α-helix	trans	-68.9	-40.9	179.8	-71.8	176.5	0	0	0	112.9	I90 V94 I450 L452	I90-L454 HydrophobicContact CG2-CB 3.8Å; V94-L454 HydrophobicContact CG2-CB 4Å; V94-L454 HydrophobicContact CG2-CD1 3.74Å; I450-L454 HydrophobicContact CG2-CD1 3.95Å; I450-L454 HydrophobicContact CG2-CG 4.41Å; I450-L454 WeakPolarHBondContact O-CG 3.47Å; I450-L454 PolarHBondContact O-N 2.98Å; L452-L454 VanDerWaalsContact C-N 3.34Å; L452-L454 PolarHBondContact O-N 3.24Å
455	I	92.2	Very high	90.5	Very high	10 Å²	10	48.9 Å²	48.9	5%	0.051	23%	0.23	C	C	.	.	H	α-helix	trans	-70.5	-39.4	177.6	-63.6	166.8	0	0	0	110.7	V94 L322 L325 S451 L452 F457 S458 N459	V94-I455 HydrophobicContact CG1-CD1 3.87Å; V94-I455 HydrophobicContact CG1-CG1 4.45Å; L322-I455 HydrophobicContact CD1-CD1 3.36Å; L325-I455 HydrophobicContact CD2-CB 4.38Å; L325-I455 HydrophobicContact CD2-CD1 4.12Å; L325-I455 HydrophobicContact CD2-CG2 3.6Å; L325-I455 HydrophobicContact CG-CG2 4.01Å; S451-I455 WeakPolarHBondContact O-CG1 3.28Å; S451-I455 PolarHBondContact O-N 3.16Å; S451-I455 VanDerWaalsContact O-N 3.17Å; L452-I455 PolarHBondContact O-N 3.28Å; I455-F457 VanDerWaalsContact C-N 3.28Å; I455-F457 PolarHBondContact O-N 3.26Å; I455-S458 WeakPolarHBondContact O-CB 3.01Å; I455-S458 PolarHBondContact O-N 2.97Å; I455-S458 VanDerWaalsContact O-N 3.11Å; I455-N459 PolarHBondContact O-N 2.87Å; I455-N459 VanDerWaalsContact O-N 3.1Å; I455-N459 PolarHBondContact O-ND2 3.34Å
456	L	93	Very high	90.7	Very high	10 Å²	10	44.4 Å²	44.4	5%	0.052	21%	0.211	C	C	.	.	H	α-helix	trans	-60.2	-38.2	178	-176.3	64.8	0	0	0	111.9	I433 Q436 L437 L440 L452 S458 N459 Y460	I433-L456 HydrophobicContact CG1-CD1 4.31Å; I433-L456 HydrophobicContact CG2-CD1 4.16Å; Q436-L456 HydrophobicContact CB-CD1 3.95Å; L437-L456 HydrophobicContact CD2-CD2 3.79Å; L437-L456 HydrophobicContact CG-CD2 4.35Å; L440-L456 HydrophobicContact CD2-CD2 4.44Å; L452-L456 WeakPolarHBondContact O-CB 3.5Å; L452-L456 PolarHBondContact O-N 2.95Å; L456-S458 VanDerWaalsContact C-N 3.33Å; L456-S458 PolarHBondContact O-N 3.29Å; L456-N459 PolarHBondContact O-N 3.06Å; L456-Y460 HydrophobicContact CD1-CD1 4.45Å; L456-Y460 HydrophobicContact CD1-CE1 3.93Å; L456-Y460 HydrophobicContact CD1-CE2 4.12Å; L456-Y460 HydrophobicContact CD2-CE2 3.81Å; L456-Y460 HydrophobicContact CG-CD2 4.06Å; L456-Y460 HydrophobicContact CG-CE1 4.27Å; L456-Y460 HydrophobicContact CG-CE2 3.52Å; L456-Y460 WeakPolarHBondContact O-CD2 3.32Å; L456-Y460 PolarHBondContact O-N 3.32Å
457	F	90.7	Very high	91	Very high	148 Å²	148	44.1 Å²	44.1	65%	0.649	21%	0.214	S	C	*	.	H	α-helix	trans	-59.3	-42.3	174.6	-177.2	-98.6	0	0	0	112.7	A453 I455 Y461	A453-F457 PolarHBondContact O-N 3.04Å; A453-F457 VanDerWaalsContact O-N 3.16Å; I455-F457 VanDerWaalsContact C-N 3.28Å; I455-F457 PolarHBondContact O-N 3.26Å; F457-Y461 PolarHBondContact O-N 3.36Å
458	S	88.2	Confident	91.2	Very high	11 Å²	11	47.9 Å²	47.9	8%	0.077	23%	0.228	C	C	.	.	H	α-helix	trans	-62.9	-44.5	175.6	174.3	0	0	0	0	111.7	C87 I455 L456 Y461 A462	C87-S458 WeakPolarHBondContact CB-OG 3.48Å; C87-S458 PolarHBondContact SG-OG 3.47Å; I455-S458 WeakPolarHBondContact O-CB 3.01Å; I455-S458 PolarHBondContact O-N 2.97Å; I455-S458 VanDerWaalsContact O-N 3.11Å; L456-S458 VanDerWaalsContact C-N 3.33Å; L456-S458 PolarHBondContact O-N 3.29Å; S458-Y461 PolarHBondContact O-N 2.63Å; S458-A462 PolarHBondContact O-N 3.23Å
459	N	92	Very high	91.1	Very high	1 Å²	1	48.1 Å²	48.1	1%	0.005	23%	0.23	C	C	.	.	H	α-helix	trans	-67.7	-36.4	-179.9	-70.6	-19.8	0	0	0	112.6	S329 E429 I433 Q436 I455 L456 Y461 A462 F463	S329-N459 WeakPolarHBondContact CB-OD1 3.32Å; S329-N459 PolarHBondContact OG-ND2 3.37Å; S329-N459 PolarHBondContact OG-OD1 2.82Å; S329-N459 VanDerWaalsContact OG-OD1 3.11Å; E429-N459 WeakPolarHBondContact OE1-CA 3.46Å; E429-N459 VanDerWaalsContact OE1-CB 3.28Å; E429-N459 WeakPolarHBondContact OE1-CB 3.48Å; I433-N459 HydrophobicContact CG1-CB 4.28Å; Q436-N459 PolarHBondContact NE2-ND2 2.62Å; Q436-N459 PolarHBondContact OE1-ND2 3.45Å; I455-N459 PolarHBondContact O-N 2.87Å; I455-N459 VanDerWaalsContact O-N 3.1Å; I455-N459 PolarHBondContact O-ND2 3.34Å; L456-N459 PolarHBondContact O-N 3.06Å; N459-Y461 VanDerWaalsContact C-N 3.28Å; N459-Y461 PolarHBondContact O-N 3.12Å; N459-A462 PolarHBondContact O-N 3.19Å; N459-A462 VanDerWaalsContact O-N 3.15Å; N459-F463 WeakPolarHBondContact O-CB 3.46Å; N459-F463 PolarHBondContact O-N 3.46Å
460	Y	93.3	Very high	91.1	Very high	98 Å²	98	49 Å²	49	38%	0.384	23%	0.227	S	C	.	.	H	α-helix	trans	-59.8	-39.1	173.5	-76.3	-34.7	0	0	0	113.1	I433 L456 F463 F464	I433-Y460 HydrophobicContact CD1-CD1 3.95Å; I433-Y460 HydrophobicContact CD1-CE1 4.3Å; I433-Y460 HydrophobicContact CG1-CD1 4.46Å; I433-Y460 HydrophobicContact CG1-CE1 4.49Å; I433-Y460 HydrophobicContact CG2-CD1 4.36Å; I433-Y460 HydrophobicContact CG2-CE1 3.64Å; L456-Y460 HydrophobicContact CD1-CD1 4.45Å; L456-Y460 HydrophobicContact CD1-CE1 3.93Å; L456-Y460 HydrophobicContact CD1-CE2 4.12Å; L456-Y460 HydrophobicContact CD2-CE2 3.81Å; L456-Y460 HydrophobicContact CG-CD2 4.06Å; L456-Y460 HydrophobicContact CG-CE1 4.27Å; L456-Y460 HydrophobicContact CG-CE2 3.52Å; L456-Y460 WeakPolarHBondContact O-CD2 3.32Å; L456-Y460 PolarHBondContact O-N 3.32Å; Y460-F463 PolarHBondContact O-N 2.65Å; Y460-F464 WeakPolarHBondContact O-CB 3.47Å; Y460-F464 PolarHBondContact O-N 3.25Å
461	Y	90.7	Very high	91.2	Very high	88 Å²	88	50 Å²	50	35%	0.345	23%	0.233	S	C	.	.	H	α-helix	trans	-65.9	-41	176.1	-179.1	-107.5	0	0	0	112	Q83 F457 S458 N459 F464 K465	Q83-Y461 HydrophobicContact CG-CD1 4.31Å; Q83-Y461 HydrophobicContact CG-CE1 3.96Å; Q83-Y461 VanDerWaalsContact NE2-CD1 3.27Å; F457-Y461 PolarHBondContact O-N 3.36Å; S458-Y461 PolarHBondContact O-N 2.63Å; N459-Y461 VanDerWaalsContact C-N 3.28Å; N459-Y461 PolarHBondContact O-N 3.12Å; Y461-F464 PolarHBondContact O-N 3.48Å; Y461-K465 HydrophobicContact CE1-CD 4.09Å; Y461-K465 PolarHBondContact O-N 3.42Å; Y461-K465 VanDerWaalsContact O-N 3.16Å; Y461-K465 WeakPolarHBondContact OH-CE 3.45Å; Y461-K465 PolarHBondContact OH-NZ 3.42Å
462	A	90	Very high	91	Very high	4 Å²	4	52.7 Å²	52.7	3%	0.033	25%	0.249	C	C	.	.	H	α-helix	trans	-63.6	-42.6	175	0	0	0	0	0	111.8	I333 Q336 S458 N459 K465 L466	I333-A462 HydrophobicContact CD1-CB 4.49Å; I333-A462 HydrophobicContact CG1-CB 3.9Å; Q336-A462 PolarHBondContact NE2-O 2.87Å; Q336-A462 VanDerWaalsContact NE2-O 3.15Å; S458-A462 PolarHBondContact O-N 3.23Å; N459-A462 PolarHBondContact O-N 3.19Å; N459-A462 VanDerWaalsContact O-N 3.15Å; A462-K465 PolarHBondContact O-N 2.83Å; A462-L466 PolarHBondContact O-N 2.83Å; A462-L466 VanDerWaalsContact O-N 3.13Å
463	F	93.7	Very high	90.8	Very high	58 Å²	58	52.5 Å²	52.5	25%	0.254	25%	0.248	S	C	.	.	H	α-helix	trans	-64.6	-43.7	176.6	-175.2	-96.7	0	0	0	112.3	L426 E429 I433 N459 Y460 K465 L466 L467	L426-F463 HydrophobicContact CD1-CD2 3.8Å; L426-F463 HydrophobicContact CD1-CE2 3.33Å; L426-F463 HydrophobicContact CD1-CZ 3.79Å; L426-F463 HydrophobicContact CG-CE2 4.01Å; L426-F463 HydrophobicContact CG-CZ 4.5Å; E429-F463 HydrophobicContact CB-CD2 4.21Å; E429-F463 HydrophobicContact CG-CB 3.96Å; E429-F463 HydrophobicContact CG-CD2 3.95Å; E429-F463 HydrophobicContact CG-CG 4.48Å; I433-F463 HydrophobicContact CD1-CB 3.56Å; I433-F463 HydrophobicContact CD1-CD1 4.48Å; I433-F463 HydrophobicContact CD1-CD2 3.89Å; I433-F463 HydrophobicContact CD1-CG 3.74Å; N459-F463 WeakPolarHBondContact O-CB 3.46Å; N459-F463 PolarHBondContact O-N 3.46Å; Y460-F463 PolarHBondContact O-N 2.65Å; F463-K465 VanDerWaalsContact C-N 3.3Å; F463-K465 PolarHBondContact O-N 3.15Å; F463-L466 PolarHBondContact O-N 3.1Å; F463-L467 HydrophobicContact CE1-CD2 4.28Å; F463-L467 WeakPolarHBondContact O-CB 3.27Å; F463-L467 PolarHBondContact O-N 3.32Å
464	F	92.5	Very high	90.6	Very high	124 Å²	124	50.9 Å²	50.9	54%	0.544	24%	0.236	S	C	.	.	H	α-helix	trans	-57.5	-43.6	175.9	171.1	-102.4	0	0	0	111.8	Y460 Y461 L467 R468	Y460-F464 WeakPolarHBondContact O-CB 3.47Å; Y460-F464 PolarHBondContact O-N 3.25Å; Y461-F464 PolarHBondContact O-N 3.48Å; F464-L467 PolarHBondContact O-N 2.82Å; F464-R468 WeakPolarHBondContact O-CB 3.47Å; F464-R468 PolarHBondContact O-N 3.11Å
465	K	88.9	Confident	90.4	Very high	23 Å²	23	55 Å²	55	10%	0.1	25%	0.252	C	S	.	.	H	α-helix	trans	-61.1	-48.8	175.6	-78.2	-175.1	174.2	172	0	112.4	Y461 A462 F463 L467 R468 D469	Y461-K465 HydrophobicContact CE1-CD 4.09Å; Y461-K465 PolarHBondContact O-N 3.42Å; Y461-K465 VanDerWaalsContact O-N 3.16Å; Y461-K465 WeakPolarHBondContact OH-CE 3.45Å; Y461-K465 PolarHBondContact OH-NZ 3.42Å; A462-K465 PolarHBondContact O-N 2.83Å; F463-K465 VanDerWaalsContact C-N 3.3Å; F463-K465 PolarHBondContact O-N 3.15Å; K465-L467 VanDerWaalsContact C-N 3.31Å; K465-L467 PolarHBondContact O-N 3.12Å; K465-R468 PolarHBondContact O-N 3.3Å; K465-D469 WeakPolarHBondContact O-CB 3.44Å; K465-D469 VanDerWaalsContact O-CG 3.25Å; K465-D469 PolarHBondContact O-N 3.27Å
466	L	91	Very high	90.1	Very high	2 Å²	2	55.4 Å²	55.4	1%	0.01	26%	0.256	C	S	.	.	H	α-helix	trans	-58.3	-45.1	176.8	-73.1	168	0	0	0	111.8	V332 Q336 L422 L425 L426 E429 A462 F463 D469 R470	V332-L466 HydrophobicContact CG1-CD1 3.69Å; Q336-L466 HydrophobicContact CG-CD2 3.49Å; Q336-L466 VanDerWaalsContact CG-CD2 3.49Å; Q336-L466 HydrophobicContact CG-CG 3.98Å; L422-L466 HydrophobicContact CD1-CD2 3.59Å; L425-L466 HydrophobicContact CB-CD1 4.25Å; L425-L466 HydrophobicContact CB-CD2 3.96Å; L425-L466 HydrophobicContact CD1-CD2 4.21Å; L426-L466 HydrophobicContact CD1-CB 4.03Å; E429-L466 HydrophobicContact CB-CD1 4.1Å; E429-L466 HydrophobicContact CG-CD1 4.36Å; A462-L466 PolarHBondContact O-N 2.83Å; A462-L466 VanDerWaalsContact O-N 3.13Å; F463-L466 PolarHBondContact O-N 3.1Å; L466-D469 PolarHBondContact O-N 3.31Å; L466-R470 WeakPolarHBondContact O-CB 3.39Å; L466-R470 PolarHBondContact O-N 3.21Å
467	L	91.8	Very high	89.7	Confident	65 Å²	65	56.5 Å²	56.5	34%	0.34	26%	0.26	S	S	.	.	H	α-helix	trans	-64.5	-45.6	-179.3	-175.8	63.1	0	0	0	111.1	L426 F463 F464 K465 D469 R470 L471	L426-L467 HydrophobicContact CD1-CB 4.42Å; F463-L467 HydrophobicContact CE1-CD2 4.28Å; F463-L467 WeakPolarHBondContact O-CB 3.27Å; F463-L467 PolarHBondContact O-N 3.32Å; F464-L467 PolarHBondContact O-N 2.82Å; K465-L467 VanDerWaalsContact C-N 3.31Å; K465-L467 PolarHBondContact O-N 3.12Å; L467-D469 PolarHBondContact O-N 3.13Å; L467-R470 PolarHBondContact O-N 3.05Å; L467-L471 HydrophobicContact CD1-CG 4.46Å; L467-L471 HydrophobicContact CG-CD1 4.22Å; L467-L471 VanDerWaalsContact O-CG 3.28Å; L467-L471 WeakPolarHBondContact O-CG 3.32Å; L467-L471 PolarHBondContact O-N 3.5Å
468	R	91	Very high	89.4	Confident	91 Å²	91	52.8 Å²	52.8	34%	0.343	25%	0.252	S	S	.	.	H	α-helix	trans	-56.8	-51.7	174.9	-179	-161.8	67.8	-178.9	-0.1	110.8	F464 K465 R470 L471 V472	F464-R468 WeakPolarHBondContact O-CB 3.47Å; F464-R468 PolarHBondContact O-N 3.11Å; K465-R468 PolarHBondContact O-N 3.3Å; R468-R470 PolarHBondContact O-N 3.47Å; R468-L471 PolarHBondContact O-N 3.49Å; R468-V472 WeakPolarHBondContact O-CG2 3.4Å; R468-V472 PolarHBondContact O-N 3.2Å
469	D	87.9	Confident	89	Confident	29 Å²	29	58.9 Å²	58.9	16%	0.155	28%	0.275	C	S	.	.	H	α-helix	trans	-62.7	-35.7	-178.8	-66.2	-1.8	0	0	0	110.6	K465 L466 L467 L473	K465-D469 WeakPolarHBondContact O-CB 3.44Å; K465-D469 VanDerWaalsContact O-CG 3.25Å; K465-D469 PolarHBondContact O-N 3.27Å; L466-D469 PolarHBondContact O-N 3.31Å; L467-D469 PolarHBondContact O-N 3.13Å; D469-L473 WeakPolarHBondContact O-CB 3.05Å; D469-L473 PolarHBondContact O-N 2.98Å
470	R	90.5	Very high	88	Confident	69 Å²	69	61.5 Å²	61.5	26%	0.26	29%	0.293	S	S	.	.	H	α-helix	trans	-68.5	-38.7	176.8	176.8	55.5	-177	79	5.1	113.4	L422 N423 L466 L467 R468 G474	L422-R470 HydrophobicContact CD2-CB 3.58Å; L422-R470 HydrophobicContact CD2-CG 4.31Å; L422-R470 HydrophobicContact CG-CB 3.99Å; N423-R470 WeakPolarHBondContact OD1-CD 3.41Å; N423-R470 PolarHBondContact OD1-NE 3.23Å; L466-R470 WeakPolarHBondContact O-CB 3.39Å; L466-R470 PolarHBondContact O-N 3.21Å; L467-R470 PolarHBondContact O-N 3.05Å; R468-R470 PolarHBondContact O-N 3.47Å; R470-G474 WeakPolarHBondContact O-CA 3.5Å; R470-G474 PolarHBondContact O-N 3.2Å
471	L	90.8	Very high	86.9	Confident	98 Å²	98	60.8 Å²	60.8	51%	0.513	31%	0.307	S	S	.	.	H	α-helix	trans	-70.1	-44.8	176.8	-70.8	173.9	0	0	0	110.9	L467 R468 K475	L467-L471 HydrophobicContact CD1-CG 4.46Å; L467-L471 HydrophobicContact CG-CD1 4.22Å; L467-L471 VanDerWaalsContact O-CG 3.28Å; L467-L471 WeakPolarHBondContact O-CG 3.32Å; L467-L471 PolarHBondContact O-N 3.5Å; R468-L471 PolarHBondContact O-N 3.49Å; L471-K475 WeakPolarHBondContact O-CB 3.49Å; L471-K475 WeakPolarHBondContact O-CG 3.17Å; L471-K475 PolarHBondContact O-N 3.16Å
472	V	88.3	Confident	85.6	Confident	55 Å²	55	58.5 Å²	58.5	33%	0.333	30%	0.304	S	S	.	.	H	α-helix	trans	-64	-52.3	178.5	174.1	0	0	0	0	110.6	L72 R468 G474 K475 A476	L72-V472 HydrophobicContact CD1-CG1 4.36Å; L72-V472 HydrophobicContact CD2-CB 4.21Å; L72-V472 HydrophobicContact CD2-CG1 3.92Å; L72-V472 HydrophobicContact CG-CG1 4.21Å; R468-V472 WeakPolarHBondContact O-CG2 3.4Å; R468-V472 PolarHBondContact O-N 3.2Å; V472-G474 VanDerWaalsContact C-N 3.33Å; V472-G474 PolarHBondContact O-N 3.41Å; V472-K475 PolarHBondContact O-N 2.79Å; V472-A476 PolarHBondContact O-N 3.2Å
473	L	86.7	Confident	83.9	Confident	4 Å²	4	62.7 Å²	62.7	2%	0.021	33%	0.331	C	S	.	.	H	α-helix	trans	-66.6	-36.9	-178.7	-165.9	62.2	0	0	0	111.7	I69 A341 L419 L422 D469 A476 Y477	I69-L473 HydrophobicContact CD1-CD1 3.74Å; I69-L473 HydrophobicContact CG2-CD1 4.14Å; A341-L473 HydrophobicContact CB-CD2 4.49Å; L419-L473 HydrophobicContact CD2-CB 3.94Å; L419-L473 HydrophobicContact CD2-CD2 3.74Å; L419-L473 HydrophobicContact CD2-CG 3.71Å; L422-L473 HydrophobicContact CD2-CD2 4.39Å; D469-L473 WeakPolarHBondContact O-CB 3.05Å; D469-L473 PolarHBondContact O-N 2.98Å; L473-A476 PolarHBondContact O-N 3.49Å; L473-Y477 HydrophobicContact CD1-CD2 3.94Å; L473-Y477 HydrophobicContact CD1-CE2 3.42Å; L473-Y477 VanDerWaalsContact CD1-CE2 3.42Å; L473-Y477 HydrophobicContact CD2-CE2 4.13Å; L473-Y477 HydrophobicContact CG-CD2 3.8Å; L473-Y477 HydrophobicContact CG-CE2 3.54Å; L473-Y477 VanDerWaalsContact O-CD2 3.24Å; L473-Y477 WeakPolarHBondContact O-CD2 3.35Å; L473-Y477 PolarHBondContact O-N 3.37Å
474	G	87.6	Confident	81.7	Confident	14 Å²	14	67 Å²	67	14%	0.144	35%	0.352	C	S	.	.	H	α-helix	trans	-61.1	-45.2	174.2	0	0	0	0	0	112.8	R470 V472 S478	R470-G474 WeakPolarHBondContact O-CA 3.5Å; R470-G474 PolarHBondContact O-N 3.2Å; V472-G474 VanDerWaalsContact C-N 3.33Å; V472-G474 PolarHBondContact O-N 3.41Å; G474-S478 WeakPolarHBondContact O-CB 3.47Å; G474-S478 PolarHBondContact O-N 2.92Å; G474-S478 PolarHBondContact O-OG 3.11Å
475	K	87.9	Confident	79.5	Confident	154 Å²	154	68.6 Å²	68.6	67%	0.67	35%	0.354	S	S	*	.	H	α-helix	trans	-63.9	-44.3	175.7	-75.7	-179.9	179.5	-178	0	111.5	L471 V472 Y477 S478 Y479	L471-K475 WeakPolarHBondContact O-CB 3.49Å; L471-K475 WeakPolarHBondContact O-CG 3.17Å; L471-K475 PolarHBondContact O-N 3.16Å; V472-K475 PolarHBondContact O-N 2.79Å; K475-Y477 PolarHBondContact O-N 2.72Å; K475-S478 WeakPolarHBondContact CA-OG 2.93Å; K475-S478 PolarHBondContact O-N 2.83Å; K475-S478 PolarHBondContact O-OG 3.36Å; K475-Y479 PolarHBondContact O-N 2.7Å
476	A	84.9	Confident	77.4	Confident	17 Å²	17	72.7 Å²	72.7	14%	0.14	38%	0.377	C	S	.	.	H	α-helix	trans	-58.6	-48.9	178.9	0	0	0	0	0	112.3	V472 L473 Y479 S480	V472-A476 PolarHBondContact O-N 3.2Å; L473-A476 PolarHBondContact O-N 3.49Å; A476-Y479 PolarHBondContact O-N 3.18Å; A476-S480 PolarHBondContact O-N 2.71Å
477	Y	84.9	Confident	75.3	Confident	34 Å²	34	77.2 Å²	77.2	13%	0.133	40%	0.401	C	S	.	.	H	α-helix	trans	-70.7	-31.5	177.5	-75.7	-66.1	0	0	0	113.3	I69 D345 H348 P418 L419 L473 K475 Y479 S480 A481	I69-Y477 HydrophobicContact CD1-CE1 4.48Å; I69-Y477 HydrophobicContact CD1-CE2 4.21Å; I69-Y477 WeakPolarHBondContact CD1-OH 3.08Å; D345-Y477 PolarHBondContact OD1-OH 2.84Å; H348-Y477 AromaticContact CD2-CE1 3.99Å; P418-Y477 HydrophobicContact CB-CD2 4.24Å; P418-Y477 HydrophobicContact CB-CE1 4.36Å; P418-Y477 HydrophobicContact CB-CE2 3.41Å; P418-Y477 VanDerWaalsContact CB-CE2 3.41Å; P418-Y477 VanDerWaalsContact CB-CZ 3.49Å; P418-Y477 WeakPolarHBondContact CB-OH 2.97Å; P418-Y477 HydrophobicContact CG-CD1 4.07Å; P418-Y477 HydrophobicContact CG-CD2 3.6Å; P418-Y477 HydrophobicContact CG-CE1 3.76Å; P418-Y477 HydrophobicContact CG-CE2 3.21Å; P418-Y477 HydrophobicContact CG-CG 4.02Å; L419-Y477 HydrophobicContact CD2-CD2 4.4Å; L473-Y477 HydrophobicContact CD1-CD2 3.94Å; L473-Y477 HydrophobicContact CD1-CE2 3.42Å; L473-Y477 VanDerWaalsContact CD1-CE2 3.42Å; L473-Y477 HydrophobicContact CD2-CE2 4.13Å; L473-Y477 HydrophobicContact CG-CD2 3.8Å; L473-Y477 HydrophobicContact CG-CE2 3.54Å; L473-Y477 VanDerWaalsContact O-CD2 3.24Å; L473-Y477 WeakPolarHBondContact O-CD2 3.35Å; L473-Y477 PolarHBondContact O-N 3.37Å; K475-Y477 PolarHBondContact O-N 2.72Å; Y477-Y479 VanDerWaalsContact C-N 3.34Å; Y477-S480 PolarHBondContact O-N 3Å; Y477-A481 PolarHBondContact O-N 2.65Å
478	S	84.6	Confident	72.9	Confident	70 Å²	70	79.6 Å²	79.6	49%	0.49	41%	0.414	S	S	.	.	H	α-helix	trans	-65.8	-37.2	176.6	70.7	0	0	0	0	112.6	G474 K475 A481 S482	G474-S478 WeakPolarHBondContact O-CB 3.47Å; G474-S478 PolarHBondContact O-N 2.92Å; G474-S478 PolarHBondContact O-OG 3.11Å; K475-S478 WeakPolarHBondContact CA-OG 2.93Å; K475-S478 PolarHBondContact O-N 2.83Å; K475-S478 PolarHBondContact O-OG 3.36Å; S478-A481 PolarHBondContact O-N 3.39Å; S478-S482 PolarHBondContact O-N 2.73Å; S478-S482 PolarHBondContact O-OG 2.78Å
479	Y	79.6	Confident	70.5	Confident	139 Å²	139	83 Å²	83	55%	0.545	43%	0.433	S	S	.	.	H	α-helix	trans	-65.8	-40.5	176.8	-167.1	-92.8	0	0	0	111.4	K475 A476 Y477 A481 S482	K475-Y479 PolarHBondContact O-N 2.7Å; A476-Y479 PolarHBondContact O-N 3.18Å; Y477-Y479 VanDerWaalsContact C-N 3.34Å; Y479-A481 VanDerWaalsContact C-N 3.35Å; Y479-A481 PolarHBondContact O-N 2.77Å; Y479-S482 PolarHBondContact O-N 3.43Å; Y479-S482 PolarHBondContact O-OG 3.28Å
480	S	72.1	Confident	68.2	Low	56 Å²	56	91.5 Å²	91.5	39%	0.392	46%	0.463	S	S	.	.	H	α-helix	trans	-70.8	-28	176.7	-62.5	0	0	0	0	114.1	C67 A476 Y477 S482	C67-S480 VanDerWaalsContact CB-OG 3.27Å; C67-S480 WeakPolarHBondContact CB-OG 3.44Å; C67-S480 PolarHBondContact SG-OG 2.83Å; A476-S480 PolarHBondContact O-N 2.71Å; Y477-S480 PolarHBondContact O-N 3Å; S480-S482 VanDerWaalsContact C-N 3.25Å; S480-S482 PolarHBondContact O-N 2.87Å
481	A	69.5	Low	65.9	Low	83 Å²	83	96.6 Å²	96.6	69%	0.686	49%	0.488	S	S	*	.	H	α-helix	trans	-74.8	-15.7	174.8	0	0	0	0	0	112.9	Y477 S478 Y479 P483	Y477-A481 PolarHBondContact O-N 2.65Å; S478-A481 PolarHBondContact O-N 3.39Å; Y479-A481 VanDerWaalsContact C-N 3.35Å; Y479-A481 PolarHBondContact O-N 2.77Å; A481-P483 WeakPolarHBondContact O-CD 3.29Å
482	S	63.1	Low	63.6	Low	40 Å²	40	99.6 Å²	99.6	28%	0.28	52%	0.517	S	S	.	.			trans	-104.3	72.6	174.8	62.7	0	0	0	0	112	S478 Y479 S480 Q484	S478-S482 PolarHBondContact O-N 2.73Å; S478-S482 PolarHBondContact O-OG 2.78Å; Y479-S482 PolarHBondContact O-N 3.43Å; Y479-S482 PolarHBondContact O-OG 3.28Å; S480-S482 VanDerWaalsContact C-N 3.25Å; S480-S482 PolarHBondContact O-N 2.87Å; S482-Q484 PolarHBondContact O-N 2.96Å; S482-Q484 VanDerWaalsContact O-N 3.12Å
483	P	55	Low	62.4	Low	91 Å²	91	101.9 Å²	101.9	59%	0.591	53%	0.526	S	S	*	.	G	3₁₀ helix	trans	-67.1	-6.6	172.8	27.6	-32.4	0	0	0	113.1	A481 R485	A481-P483 WeakPolarHBondContact O-CD 3.29Å; P483-R485 VanDerWaalsContact C-N 3.32Å; P483-R485 PolarHBondContact O-N 3.43Å
484	Q	47.7	Very low	61.1	Low	148 Å²	148	107 Å²	107	69%	0.692	55%	0.553	S	S	*	*	G	3₁₀ helix	trans	-71	-16.2	-174.5	-144.2	95.9	-1.9	0	0	114.8	S482	S482-Q484 PolarHBondContact O-N 2.96Å; S482-Q484 VanDerWaalsContact O-N 3.12Å
485	R	45.5	Very low	59.6	Low	159 Å²	159	112.2 Å²	112.2	60%	0.6	58%	0.575	S	S	*	*	G	3₁₀ helix	trans	-84.8	-19.9	-179	-69.9	-167	-154	155.7	6.9	114.9	P483 L487 D488	P483-R485 VanDerWaalsContact C-N 3.32Å; P483-R485 PolarHBondContact O-N 3.43Å; R485-L487 PolarHBondContact O-N 2.97Å; R485-D488 PolarHBondContact O-N 3.16Å
486	D	45.6	Very low	58	Low	109 Å²	109	109.7 Å²	109.7	58%	0.583	57%	0.57	S	S	*	*	T	Hydrogen-bonded Turn	trans	-75.9	-8.8	175.2	-75.7	-19.7	0	0	0	112.5
487	L	47.3	Very low	56.3	Low	96 Å²	96	115.5 Å²	115.5	50%	0.503	60%	0.597	S	S	.	*	T	Hydrogen-bonded Turn	trans	-81.4	-29.8	170.2	-83.3	156.7	0	0	0	112.6	R485 H489 R490 F491	R485-L487 PolarHBondContact O-N 2.97Å; L487-H489 VanDerWaalsContact C-N 3.33Å; L487-H489 PolarHBondContact O-N 3.32Å; L487-R490 PolarHBondContact O-N 3.38Å; L487-F491 WeakPolarHBondContact O-CD2 3.48Å
488	D	40.3	Very low	54.4	Low	116 Å²	116	120.9 Å²	120.9	62%	0.62	63%	0.627	S	S	*	*	G	3₁₀ helix	trans	-73.8	-24.7	-179.3	-71.6	-19.9	0	0	0	112.5	R485 R490	R485-D488 PolarHBondContact O-N 3.16Å; D488-R490 VanDerWaalsContact C-N 3.31Å; D488-R490 PolarHBondContact O-N 3.45Å
489	H	40.5	Very low	52.2	Low	161 Å²	161	124.6 Å²	124.6	75%	0.745	64%	0.637	S	S	*	*	G	3₁₀ helix	trans	-82.3	0.7	172.9	-82.6	-53	0	0	0	114.9	L487	L487-H489 VanDerWaalsContact C-N 3.33Å; L487-H489 PolarHBondContact O-N 3.32Å
490	R	39.5	Very low	50.1	Low	209 Å²	209	123.5 Å²	123.5	79%	0.789	64%	0.644	S	S	*	*	G	3₁₀ helix	trans	-104.4	-1.1	169.1	-74.5	-166.2	-161.8	-163.5	4.5	114.2	L487 D488	L487-R490 PolarHBondContact O-N 3.38Å; D488-R490 VanDerWaalsContact C-N 3.31Å; D488-R490 PolarHBondContact O-N 3.45Å
491	F	43.6	Very low	48.3	Very low	176 Å²	176	129.1 Å²	129.1	77%	0.772	67%	0.665	S	S	*	*			trans	-120.2	17.1	176.5	-69.1	-70.2	0	0	0	113.8	L487	L487-F491 WeakPolarHBondContact O-CD2 3.48Å
492	S	42.2	Very low	46.4	Very low	161 Å²	161	133.3 Å²	133.3	100%	1.126	66%	0.664	S	S	*	*			trans	-108	0	151.2	-64.7	0	0	0	0	108.2

Retrieved 492 of 492 residues in 3450.3 ms (Link to these results)

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