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Gremlin-2

Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells.

AlphaFold DB , UniProt , Accession Q9H772, Species HUMAN (Homo sapiens, Human), Gene GREM2, Length 168 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	62.6	Low	78.8	Confident	215 Å²	215	137.5 Å²	137.5	100%	1.059	67%	0.666	S	S	*	*				0	-27	0	-130.2	164.1	83.6	0	0	113.9	W3	M1-W3 PolarHBondContact O-N 2.84Å
2	F	67.1	Low	79.4	Confident	171 Å²	171	133.6 Å²	133.6	75%	0.75	66%	0.656	S	S	*	*	H	α-helix	trans	-65	-25.6	-175.4	-60.5	-75.7	0	0	0	116.3	K4 L5 S6	F2-K4 PolarHBondContact O-N 3.05Å; F2-L5 PolarHBondContact O-N 3.43Å; F2-S6 PolarHBondContact O-N 2.03Å
3	W	69.4	Low	79.6	Confident	212 Å²	212	127.5 Å²	127.5	80%	0.803	64%	0.64	S	S	*	*	H	α-helix	trans	-64.7	-38.6	-178.5	-167.6	-8.5	0	0	0	113.1	M1 L5 S6 L7	M1-W3 PolarHBondContact O-N 2.84Å; W3-L5 VanDerWaalsContact C-N 3.28Å; W3-L5 PolarHBondContact O-N 2.76Å; W3-S6 PolarHBondContact O-N 3.4Å; W3-L7 PolarHBondContact O-N 2.91Å
4	K	77.2	Confident	79.9	Confident	179 Å²	179	124.4 Å²	124.4	78%	0.778	63%	0.631	S	S	*	*	H	α-helix	trans	-63.7	-35.6	178.4	-71.1	-159.7	173.2	-171.7	0	112.3	F2 L7 S8	F2-K4 PolarHBondContact O-N 3.05Å; K4-L7 PolarHBondContact O-N 3.41Å; K4-S8 PolarHBondContact O-N 3.18Å; K4-S8 VanDerWaalsContact O-N 3.14Å
5	L	81.4	Confident	79.7	Confident	114 Å²	114	123.7 Å²	123.7	60%	0.597	63%	0.628	S	S	*	*	H	α-helix	trans	-67.1	-45.1	176.5	-66.4	171.9	0	0	0	110.9	F2 W3 L7 S8 L9	F2-L5 PolarHBondContact O-N 3.43Å; W3-L5 VanDerWaalsContact C-N 3.28Å; W3-L5 PolarHBondContact O-N 2.76Å; L5-L7 VanDerWaalsContact C-N 3.33Å; L5-L7 PolarHBondContact O-N 2.89Å; L5-S8 PolarHBondContact O-N 3.03Å; L5-S8 PolarHBondContact O-OG 2.81Å; L5-L9 PolarHBondContact O-N 2.83Å
6	S	81.8	Confident	79.4	Confident	64 Å²	64	121.1 Å²	121.1	45%	0.448	62%	0.62	S	S	.	*	H	α-helix	trans	-58.2	-44.7	175.2	-64.6	0	0	0	0	112.1	F2 W3 S8 L9 F10	F2-S6 PolarHBondContact O-N 2.03Å; W3-S6 PolarHBondContact O-N 3.4Å; S6-S8 VanDerWaalsContact C-N 3.32Å; S6-S8 PolarHBondContact O-N 2.83Å; S6-L9 PolarHBondContact O-N 3.4Å; S6-F10 WeakPolarHBondContact O-CD2 3.15Å; S6-F10 PolarHBondContact O-N 2.85Å
7	L	84.3	Confident	78.8	Confident	105 Å²	105	123.4 Å²	123.4	55%	0.55	63%	0.625	S	S	.	*	H	α-helix	trans	-61.6	-40.6	179.8	-155.8	90.9	0	0	0	112.1	W3 K4 L5 F10 L11	W3-L7 PolarHBondContact O-N 2.91Å; K4-L7 PolarHBondContact O-N 3.41Å; L5-L7 VanDerWaalsContact C-N 3.33Å; L5-L7 PolarHBondContact O-N 2.89Å; L7-F10 PolarHBondContact O-N 3.47Å; L7-L11 PolarHBondContact O-N 3.18Å
8	S	84.5	Confident	78.1	Confident	58 Å²	58	120.8 Å²	120.8	41%	0.406	62%	0.616	S	S	.	*	H	α-helix	trans	-66.6	-39.1	176.7	68.9	0	0	0	0	112.5	K4 L5 S6 L11 V12	K4-S8 PolarHBondContact O-N 3.18Å; K4-S8 VanDerWaalsContact O-N 3.14Å; L5-S8 PolarHBondContact O-N 3.03Å; L5-S8 PolarHBondContact O-OG 2.81Å; S6-S8 VanDerWaalsContact C-N 3.32Å; S6-S8 PolarHBondContact O-N 2.83Å; S8-L11 PolarHBondContact O-N 2.88Å; S8-V12 WeakPolarHBondContact O-CG2 3.5Å; S8-V12 PolarHBondContact O-N 2.7Å
9	L	85.2	Confident	77	Confident	135 Å²	135	118 Å²	118	71%	0.707	61%	0.613	S	S	*	*	H	α-helix	trans	-65.2	-41.5	178	-147.5	89.9	0	0	0	111.2	L5 S6 V12 A13	L5-L9 PolarHBondContact O-N 2.83Å; S6-L9 PolarHBondContact O-N 3.4Å; L9-V12 PolarHBondContact O-N 3.01Å; L9-A13 WeakPolarHBondContact O-CB 3.45Å; L9-A13 PolarHBondContact O-N 2.85Å
10	F	85.6	Confident	75.9	Confident	153 Å²	153	119 Å²	119	67%	0.671	61%	0.614	S	S	*	*	H	α-helix	trans	-62.6	-44.2	174.5	-87.3	-71.8	0	0	0	112.1	S6 L7 V12 A13 V14	S6-F10 WeakPolarHBondContact O-CD2 3.15Å; S6-F10 PolarHBondContact O-N 2.85Å; L7-F10 PolarHBondContact O-N 3.47Å; F10-V12 PolarHBondContact O-N 2.92Å; F10-A13 PolarHBondContact O-N 2.8Å; F10-V14 VanDerWaalsContact O-CG2 3.31Å; F10-V14 WeakPolarHBondContact O-CG2 3.32Å; F10-V14 PolarHBondContact O-N 3.48Å
11	L	88.3	Confident	74.9	Confident	106 Å²	106	117 Å²	117	56%	0.555	62%	0.616	S	S	*	*	H	α-helix	trans	-60.4	-45	177.4	-96.5	162	0	0	0	112.3	L7 S8 V14 L15	L7-L11 PolarHBondContact O-N 3.18Å; S8-L11 PolarHBondContact O-N 2.88Å; L11-V14 PolarHBondContact O-N 2.73Å; L11-L15 WeakPolarHBondContact O-CG 3.5Å; L11-L15 PolarHBondContact O-N 2.75Å
12	V	86.1	Confident	74.4	Confident	91 Å²	91	117 Å²	117	55%	0.552	60%	0.604	S	S	*	*	H	α-helix	trans	-64.4	-43.2	177.2	175.9	0	0	0	0	111	S8 L9 F10 V14 L15 V16	S8-V12 WeakPolarHBondContact O-CG2 3.5Å; S8-V12 PolarHBondContact O-N 2.7Å; L9-V12 PolarHBondContact O-N 3.01Å; F10-V12 PolarHBondContact O-N 2.92Å; V12-V14 VanDerWaalsContact C-N 3.34Å; V12-V14 PolarHBondContact O-N 2.81Å; V12-L15 PolarHBondContact O-N 3.4Å; V12-V16 HydrophobicContact CG1-CG2 4.4Å; V12-V16 WeakPolarHBondContact O-CG2 3.11Å; V12-V16 PolarHBondContact O-N 2.99Å
13	A	81.6	Confident	73.2	Confident	54 Å²	54	117.3 Å²	117.3	45%	0.446	61%	0.605	S	S	.	*	H	α-helix	trans	-61.6	-40.2	177.3	0	0	0	0	0	112.5	L9 F10 V16 K17	L9-A13 WeakPolarHBondContact O-CB 3.45Å; L9-A13 PolarHBondContact O-N 2.85Å; F10-A13 PolarHBondContact O-N 2.8Å; A13-V16 PolarHBondContact O-N 2.9Å; A13-K17 WeakPolarHBondContact O-CB 3.22Å; A13-K17 VanDerWaalsContact O-CG 3.22Å; A13-K17 WeakPolarHBondContact O-CG 3.05Å; A13-K17 PolarHBondContact O-N 2.96Å
14	V	84.1	Confident	72	Confident	84 Å²	84	114 Å²	114	51%	0.509	60%	0.603	S	S	.	*	H	α-helix	trans	-65.1	-43.3	174.9	172.6	0	0	0	0	110.9	F10 L11 V12 V16 K17 V18	F10-V14 VanDerWaalsContact O-CG2 3.31Å; F10-V14 WeakPolarHBondContact O-CG2 3.32Å; F10-V14 PolarHBondContact O-N 3.48Å; L11-V14 PolarHBondContact O-N 2.73Å; V12-V14 VanDerWaalsContact C-N 3.34Å; V12-V14 PolarHBondContact O-N 2.81Å; V14-V16 PolarHBondContact O-N 2.88Å; V14-K17 PolarHBondContact O-N 2.88Å; V14-V18 HydrophobicContact CG1-CG2 4.36Å; V14-V18 VanDerWaalsContact O-CG2 3.29Å; V14-V18 WeakPolarHBondContact O-CG2 3.28Å; V14-V18 PolarHBondContact O-N 2.82Å
15	L	76.4	Confident	70.5	Confident	114 Å²	114	116.4 Å²	116.4	60%	0.597	61%	0.607	S	S	*	*	H	α-helix	trans	-63.6	-39.8	177.9	-71.7	172.1	0	0	0	112.4	L11 V12 V18 A19	L11-L15 WeakPolarHBondContact O-CG 3.5Å; L11-L15 PolarHBondContact O-N 2.75Å; V12-L15 PolarHBondContact O-N 3.4Å; L15-V18 PolarHBondContact O-N 2.86Å; L15-A19 WeakPolarHBondContact O-CB 3.32Å; L15-A19 PolarHBondContact O-N 2.8Å
16	V	75.7	Confident	68.6	Low	82 Å²	82	116.3 Å²	116.3	50%	0.497	61%	0.613	S	S	.	*	H	α-helix	trans	-64.3	-44.8	174.5	174.4	0	0	0	0	110.7	V12 A13 V14 V18 A19 E20	V12-V16 HydrophobicContact CG1-CG2 4.4Å; V12-V16 WeakPolarHBondContact O-CG2 3.11Å; V12-V16 PolarHBondContact O-N 2.99Å; A13-V16 PolarHBondContact O-N 2.9Å; V14-V16 PolarHBondContact O-N 2.88Å; V16-V18 VanDerWaalsContact C-N 3.32Å; V16-V18 PolarHBondContact O-N 3.34Å; V16-A19 PolarHBondContact O-N 2.83Å; V16-E20 PolarHBondContact O-N 2.93Å
17	K	68.7	Low	66.9	Low	160 Å²	160	118.6 Å²	118.6	70%	0.696	64%	0.636	S	S	*	*	H	α-helix	trans	-61.1	-38.4	176.2	-72.2	-85.4	-179.1	168	0	112.6	A13 V14 A21	A13-K17 WeakPolarHBondContact O-CB 3.22Å; A13-K17 VanDerWaalsContact O-CG 3.22Å; A13-K17 WeakPolarHBondContact O-CG 3.05Å; A13-K17 PolarHBondContact O-N 2.96Å; V14-K17 PolarHBondContact O-N 2.88Å; K17-A21 WeakPolarHBondContact O-CB 3.29Å; K17-A21 PolarHBondContact O-N 2.75Å
18	V	66.8	Low	65.1	Low	77 Å²	77	117 Å²	117	47%	0.467	65%	0.645	S	S	.	*	H	α-helix	trans	-69.9	-37.8	176.7	171.7	0	0	0	0	111.6	V14 L15 V16 E20 R22	V14-V18 HydrophobicContact CG1-CG2 4.36Å; V14-V18 VanDerWaalsContact O-CG2 3.29Å; V14-V18 WeakPolarHBondContact O-CG2 3.28Å; V14-V18 PolarHBondContact O-N 2.82Å; L15-V18 PolarHBondContact O-N 2.86Å; V16-V18 VanDerWaalsContact C-N 3.32Å; V16-V18 PolarHBondContact O-N 3.34Å; V18-E20 VanDerWaalsContact C-N 3.35Å; V18-R22 PolarHBondContact O-N 3.35Å
19	A	57.1	Low	62.9	Low	68 Å²	68	118.3 Å²	118.3	56%	0.562	66%	0.66	S	S	*	*	H	α-helix	trans	-65.6	-38.7	175.9	0	0	0	0	0	111.8	L15 V16 R22	L15-A19 WeakPolarHBondContact O-CB 3.32Å; L15-A19 PolarHBondContact O-N 2.8Å; V16-A19 PolarHBondContact O-N 2.83Å; A19-R22 PolarHBondContact O-N 3.26Å
20	E	55	Low	61	Low	137 Å²	137	118.3 Å²	118.3	64%	0.64	66%	0.659	S	S	*	*	H	α-helix	trans	-72.7	-36.8	178.8	-156.1	134.1	-145.3	0	0	112.3	V16 V18 R22 K23	V16-E20 PolarHBondContact O-N 2.93Å; V18-E20 VanDerWaalsContact C-N 3.35Å; E20-R22 PolarHBondContact O-N 3.43Å; E20-K23 PolarHBondContact O-N 2.85Å
21	A	53.7	Low	59.3	Low	78 Å²	78	115.1 Å²	115.1	65%	0.645	65%	0.654	S	S	*	*	H	α-helix	trans	-64.4	-19.6	173.6	0	0	0	0	0	113.5	K17 K23	K17-A21 WeakPolarHBondContact O-CB 3.29Å; K17-A21 PolarHBondContact O-N 2.75Å; A21-K23 VanDerWaalsContact C-N 3.32Å
22	R	52	Low	57.1	Low	214 Å²	214	114.3 Å²	114.3	81%	0.808	66%	0.657	S	S	*	*	T	Hydrogen-bonded Turn	trans	-78.8	-10	174.1	-79.1	-173.5	171.8	179.7	-0.7	114	V18 A19 E20	V18-R22 PolarHBondContact O-N 3.35Å; A19-R22 PolarHBondContact O-N 3.26Å; E20-R22 PolarHBondContact O-N 3.43Å
23	K	42.4	Very low	55.7	Low	179 Å²	179	115.9 Å²	115.9	78%	0.778	67%	0.669	S	S	*	*	T	Hydrogen-bonded Turn	trans	-89.4	-6.1	-176.2	-154.6	173.6	177.8	-174.7	0	115.2	E20 A21	E20-K23 PolarHBondContact O-N 2.85Å; A21-K23 VanDerWaalsContact C-N 3.32Å
24	N	43.8	Very low	54.4	Low	141 Å²	141	123.1 Å²	123.1	75%	0.754	69%	0.686	S	S	*	*			trans	-114.4	42.1	-175.3	-65.7	-23.5	0	0	0	114.4
25	R	46.1	Very low	52.7	Low	230 Å²	230	128.6 Å²	128.6	87%	0.868	70%	0.703	S	S	*	*			trans	-95.9	118.5	160.1	-97.8	-173.6	171.1	100.6	0.1	108.9	A27	R25-A27 PolarHBondContact O-N 2.86Å
26	P	42.1	Very low	51	Low	112 Å²	112	130.6 Å²	130.6	73%	0.727	72%	0.715	S	S	*	*			trans	-59.3	126.7	167.9	23.5	-29.7	0	0	0	108.4	G28	P26-G28 PolarHBondContact O-N 3.3Å
27	A	46.5	Very low	49.4	Very low	112 Å²	112	129.6 Å²	129.6	93%	0.926	72%	0.72	S	S	*	*	T	Hydrogen-bonded Turn	trans	-62.9	108.2	171	0	0	0	0	0	107.7	R25	R25-A27 PolarHBondContact O-N 2.86Å
28	G	45.6	Very low	48.1	Very low	72 Å²	72	127.7 Å²	127.7	74%	0.742	73%	0.728	S	S	*	*	T	Hydrogen-bonded Turn	trans	152.9	-12	171.7	0	0	0	0	0	117.8	P26 I30	P26-G28 PolarHBondContact O-N 3.3Å; G28-I30 PolarHBondContact O-N 2.02Å
29	A	37.7	Very low	47.5	Very low	86 Å²	86	128.4 Å²	128.4	71%	0.711	74%	0.736	S	S	*	*			trans	-77.9	109.7	176.5	0	0	0	0	0	110.7	P31	A29-P31 WeakPolarHBondContact O-CD 3.44Å
30	I	45.6	Very low	47.2	Very low	135 Å²	135	132.4 Å²	132.4	69%	0.692	75%	0.748	S	S	*	*	P	Polyproline II helix	trans	-60.8	121.6	171.5	-60.2	170.2	0	0	0	108.2	G28	G28-I30 PolarHBondContact O-N 2.02Å
31	P	49.8	Very low	47.1	Very low	86 Å²	86	129.3 Å²	129.3	56%	0.558	74%	0.735	S	S	*	*	P	Polyproline II helix	trans	-67.7	144.3	174.3	-16.2	29.9	0	0	0	111.6	A29	A29-P31 WeakPolarHBondContact O-CD 3.44Å
32	S	42.4	Very low	47.3	Very low	88 Å²	88	129.9 Å²	129.9	62%	0.615	74%	0.735	S	S	*	*	P	Polyproline II helix	trans	-58.6	135	171.3	169.5	0	0	0	0	111.1	Y34	S32-Y34 PolarHBondContact O-N 2.04Å; S32-Y34 PolarHBondContact OG-N 3.36Å
33	P	57.1	Low	47.6	Very low	125 Å²	125	127.1 Å²	127.1	81%	0.812	73%	0.731	S	S	*	*	S	Bend	trans	-65.2	-17.2	178.1	-20.4	32	0	0	0	114.7
34	Y	53	Low	48.2	Very low	205 Å²	205	126.9 Å²	126.9	80%	0.804	73%	0.725	S	S	*	*			trans	-96.8	99.4	180	-68.9	-85.4	0	0	0	109.8	S32	S32-Y34 PolarHBondContact O-N 2.04Å; S32-Y34 PolarHBondContact OG-N 3.36Å
35	K	48.3	Very low	48.7	Very low	199 Å²	199	126.9 Å²	126.9	87%	0.865	72%	0.715	S	S	*	*			trans	-122	109.6	161.6	-167.9	173.6	-177.2	178.9	0	109.2
36	D	41.7	Very low	49.3	Very low	157 Å²	157	121.8 Å²	121.8	84%	0.84	70%	0.701	S	S	*	*			trans	-60.8	135	171.2	-63.5	-44.6	0	0	0	110.6
37	G	42.4	Very low	50.3	Low	60 Å²	60	123 Å²	123	62%	0.619	70%	0.697	S	S	*	*			trans	176.1	100	179.8	0	0	0	0	0	114
38	S	42.2	Very low	50.9	Low	121 Å²	121	122 Å²	122	85%	0.846	67%	0.673	S	S	*	*			trans	-54.7	145.9	-179.1	-173.9	0	0	0	0	116.5
39	S	52.5	Low	51.4	Low	92 Å²	92	123.7 Å²	123.7	64%	0.643	66%	0.664	S	S	*	*	S	Bend	trans	57.2	69.1	149.8	-166.1	0	0	0	0	119.8
40	N	51.8	Low	52.6	Low	151 Å²	151	127.4 Å²	127.4	81%	0.807	66%	0.664	S	S	*	*			trans	-170.1	50.8	139.8	-95.3	-9	0	0	0	109.6
41	N	52.1	Low	53.3	Low	72 Å²	72	126.1 Å²	126.1	39%	0.385	66%	0.655	S	S	.	*	H	α-helix	trans	-90.4	-28.9	-154.6	-111.2	-14.2	0	0	0	114.7	E43 R44 W45	N41-E43 PolarHBondContact O-N 3.15Å; N41-R44 PolarHBondContact O-N 2.04Å; N41-W45 PolarHBondContact ND2-NE1 3.34Å; N41-W45 VanDerWaalsContact O-CB 3.31Å; N41-W45 WeakPolarHBondContact O-CB 3.43Å; N41-W45 PolarHBondContact O-N 3.17Å; N41-W45 PolarHBondContact OD1-NE1 3.13Å
42	S	57.8	Low	53.3	Low	90 Å²	90	125.4 Å²	125.4	63%	0.629	65%	0.649	S	S	*	*	H	α-helix	trans	-59.4	-49.2	-166.5	-172.8	0	0	0	0	114.3	Q46	S42-Q46 PolarHBondContact O-N 3.04Å
43	E	59.9	Low	53.8	Low	156 Å²	156	126.3 Å²	126.3	73%	0.729	65%	0.646	S	S	*	*	H	α-helix	trans	-71.2	-37.9	-179	-62.4	-175.3	159.8	0	0	112.2	N41 Q46 H47	N41-E43 PolarHBondContact O-N 3.15Å; E43-Q46 PolarHBondContact O-N 2.78Å; E43-H47 PolarHBondContact O-CD2 2.9Å; E43-H47 PolarHBondContact O-N 3.02Å; E43-H47 VanDerWaalsContact O-N 3.09Å
44	R	54.2	Low	53.4	Low	174 Å²	174	125.6 Å²	125.6	66%	0.657	65%	0.651	S	S	*	*	H	α-helix	trans	-67.9	-39.4	178.2	-173.5	168	-179.4	137.9	1.7	112	N41 H47 Q48	N41-R44 PolarHBondContact O-N 2.04Å; R44-H47 PolarHBondContact O-N 3.04Å; R44-Q48 WeakPolarHBondContact O-CG 3.44Å; R44-Q48 PolarHBondContact O-N 3.42Å
45	W	54.4	Low	53.2	Low	142 Å²	142	119.4 Å²	119.4	54%	0.538	64%	0.638	S	S	.	*	H	α-helix	trans	-62.6	-42.7	174.1	-88.9	83.8	0	0	0	111.6	N41 H47 Q48 I49	N41-W45 PolarHBondContact ND2-NE1 3.34Å; N41-W45 VanDerWaalsContact O-CB 3.31Å; N41-W45 WeakPolarHBondContact O-CB 3.43Å; N41-W45 PolarHBondContact O-N 3.17Å; N41-W45 PolarHBondContact OD1-NE1 3.13Å; W45-H47 VanDerWaalsContact C-N 3.34Å; W45-H47 PolarHBondContact O-N 3.39Å; W45-Q48 PolarHBondContact O-N 2.72Å; W45-I49 VanDerWaalsContact O-CG1 3.31Å; W45-I49 WeakPolarHBondContact O-CG1 3.42Å; W45-I49 PolarHBondContact O-N 3.28Å
46	Q	59.3	Low	53.5	Low	122 Å²	122	115.6 Å²	115.6	57%	0.57	64%	0.636	S	S	*	*	H	α-helix	trans	-64.2	-37.9	176.9	-78.4	172.8	-20.1	0	0	112.6	S42 E43 K50	S42-Q46 PolarHBondContact O-N 3.04Å; E43-Q46 PolarHBondContact O-N 2.78Å; Q46-K50 PolarHBondContact O-N 3.13Å
47	H	61.6	Low	54	Low	139 Å²	139	117.1 Å²	117.1	64%	0.644	64%	0.638	S	S	*	*	H	α-helix	trans	-64.9	-41.3	172.3	-91	-86.4	0	0	0	112.2	E43 R44 W45 K50 E51	E43-H47 PolarHBondContact O-CD2 2.9Å; E43-H47 PolarHBondContact O-N 3.02Å; E43-H47 VanDerWaalsContact O-N 3.09Å; R44-H47 PolarHBondContact O-N 3.04Å; W45-H47 VanDerWaalsContact C-N 3.34Å; W45-H47 PolarHBondContact O-N 3.39Å; H47-K50 PolarHBondContact O-N 2.79Å; H47-E51 PolarHBondContact O-N 3.07Å
48	Q	59.7	Low	54.5	Low	90 Å²	90	123.1 Å²	123.1	42%	0.421	65%	0.65	S	S	.	*	H	α-helix	trans	-65.4	-39.3	176.4	-74.8	-178.4	-75.1	0	0	112.6	R44 W45 K50 E51 V52	R44-Q48 WeakPolarHBondContact O-CG 3.44Å; R44-Q48 PolarHBondContact O-N 3.42Å; W45-Q48 PolarHBondContact O-N 2.72Å; Q48-K50 VanDerWaalsContact C-N 3.28Å; Q48-K50 PolarHBondContact O-N 3Å; Q48-E51 WeakPolarHBondContact O-CB 3.15Å; Q48-E51 PolarHBondContact O-N 3.1Å; Q48-E51 VanDerWaalsContact O-N 3.07Å; Q48-V52 WeakPolarHBondContact O-CG2 3.19Å; Q48-V52 PolarHBondContact O-N 2.77Å
49	I	57	Low	55.4	Low	108 Å²	108	119.4 Å²	119.4	55%	0.554	63%	0.626	S	S	*	*	H	α-helix	trans	-61.7	-35.4	178.2	-68.9	166.2	0	0	0	111.6	W45 E51 V52	W45-I49 VanDerWaalsContact O-CG1 3.31Å; W45-I49 WeakPolarHBondContact O-CG1 3.42Å; W45-I49 PolarHBondContact O-N 3.28Å; I49-E51 VanDerWaalsContact C-N 3.31Å; I49-E51 PolarHBondContact O-N 2.7Å; I49-V52 PolarHBondContact O-N 3.42Å; I49-V52 VanDerWaalsContact O-N 3.17Å
50	K	61.4	Low	55.9	Low	163 Å²	163	119.9 Å²	119.9	71%	0.709	62%	0.621	S	S	*	*	H	α-helix	trans	-70.4	-25.6	176	-74.2	-179.2	179.3	174.9	0	113.5	Q46 H47 Q48 V52 R65	Q46-K50 PolarHBondContact O-N 3.13Å; H47-K50 PolarHBondContact O-N 2.79Å; Q48-K50 VanDerWaalsContact C-N 3.28Å; Q48-K50 PolarHBondContact O-N 3Å; K50-V52 VanDerWaalsContact C-N 3.31Å; K50-R65 PolarHBondContact O-NH1 3.21Å; K50-R65 VanDerWaalsContact O-NH1 3.15Å
51	E	60.5	Low	56.6	Low	109 Å²	109	117.5 Å²	117.5	51%	0.509	61%	0.612	S	S	.	*	H	α-helix	trans	-75.4	-23.1	171.8	-69.9	-176	167.8	0	0	111.8	H47 Q48 I49 R65	H47-E51 PolarHBondContact O-N 3.07Å; Q48-E51 WeakPolarHBondContact O-CB 3.15Å; Q48-E51 PolarHBondContact O-N 3.1Å; Q48-E51 VanDerWaalsContact O-N 3.07Å; I49-E51 VanDerWaalsContact C-N 3.31Å; I49-E51 PolarHBondContact O-N 2.7Å; E51-R65 HydrophobicContact CB-CB 4.49Å; E51-R65 VanDerWaalsContact O-CB 3.24Å; E51-R65 WeakPolarHBondContact O-CB 3.22Å; E51-R65 WeakPolarHBondContact O-CD 3.02Å
52	V	51.1	Low	57.5	Low	70 Å²	70	117.3 Å²	117.3	42%	0.424	61%	0.613	S	S	.	*	S	Bend	trans	-86.1	126.8	-178.9	-179.9	0	0	0	0	110	Q48 I49 K50 A54 V61	Q48-V52 WeakPolarHBondContact O-CG2 3.19Å; Q48-V52 PolarHBondContact O-N 2.77Å; I49-V52 PolarHBondContact O-N 3.42Å; I49-V52 VanDerWaalsContact O-N 3.17Å; K50-V52 VanDerWaalsContact C-N 3.31Å; V52-A54 PolarHBondContact O-N 3.07Å; V52-V61 HydrophobicContact CG1-CG2 4.25Å
53	L	51.8	Low	58.5	Low	108 Å²	108	115 Å²	115	57%	0.565	60%	0.595	S	S	*	*	P	Polyproline II helix	trans	-66.4	122.9	174.7	-63.1	174.9	0	0	0	109.2	S55 L68	L53-S55 PolarHBondContact O-N 3.47Å; L53-L68 HydrophobicContact CD1-CD1 3.88Å
54	A	48	Very low	59.4	Low	110 Å²	110	111 Å²	111	91%	0.909	58%	0.577	S	S	*	*	P	Polyproline II helix	trans	-66.2	117.3	178.1	0	0	0	0	0	110.6	V52	V52-A54 PolarHBondContact O-N 3.07Å
55	S	49.7	Very low	60.5	Low	75 Å²	75	108.9 Å²	108.9	52%	0.524	57%	0.569	S	S	.	*			trans	-110.1	143.5	167.8	-166.5	0	0	0	0	109.5	L53 Q57 A59	L53-S55 PolarHBondContact O-N 3.47Å; S55-Q57 PolarHBondContact O-N 3.37Å; S55-A59 VanDerWaalsContact CB-CA 3.49Å
56	S	54	Low	61.9	Low	119 Å²	119	108.7 Å²	108.7	83%	0.832	57%	0.572	S	S	*	*	S	Bend	trans	-79.5	-16.3	-163.1	48.6	0	0	0	0	115.8
57	Q	53	Low	62.9	Low	188 Å²	188	109 Å²	109	88%	0.879	57%	0.568	S	S	*	*	S	Bend	trans	-143	-25.3	179.2	-66.5	-172.3	1.2	0	0	116.9	S55	S55-Q57 PolarHBondContact O-N 3.37Å
58	E	53.3	Low	64	Low	186 Å²	186	104.2 Å²	104.2	87%	0.869	55%	0.547	S	S	*	.			trans	-164.5	91.4	164.6	-150	165	-174.3	0	0	107.4	L60	E58-L60 PolarHBondContact O-N 3.15Å; E58-L60 VanDerWaalsContact O-N 3.09Å
59	A	59.5	Low	65.2	Low	43 Å²	43	108 Å²	108	36%	0.355	56%	0.563	S	S	.	*			trans	-71.7	105.8	177.4	0	0	0	0	0	108	S55 V61	S55-A59 VanDerWaalsContact CB-CA 3.49Å; A59-V61 PolarHBondContact O-N 3.33Å
60	L	63.3	Low	66.9	Low	103 Å²	103	107.9 Å²	107.9	54%	0.539	57%	0.571	S	S	.	*			trans	-63.1	108.9	160.9	178.7	59.8	0	0	0	107.4	E58 V62 I106	E58-L60 PolarHBondContact O-N 3.15Å; E58-L60 VanDerWaalsContact O-N 3.09Å; L60-V62 WeakPolarHBondContact O-CG2 3.18Å; L60-V62 PolarHBondContact O-N 3.17Å; L60-I106 HydrophobicContact CD2-CD1 3.57Å; L60-I106 HydrophobicContact CD2-CG2 4.23Å; L60-I106 HydrophobicContact CG-CD1 4.33Å
61	V	67.4	Low	68.4	Low	100 Å²	100	103.7 Å²	103.7	61%	0.606	56%	0.557	S	S	*	*			trans	-73.6	98.3	176.6	-178.2	0	0	0	0	108	V52 A59	V52-V61 HydrophobicContact CG1-CG2 4.25Å; A59-V61 PolarHBondContact O-N 3.33Å
62	V	70.3	Confident	70.2	Confident	68 Å²	68	102.8 Å²	102.8	41%	0.412	55%	0.548	S	S	.	.			trans	-76.6	-45	-176.1	-168.9	0	0	0	0	111.6	L60 F104 I106	L60-V62 WeakPolarHBondContact O-CG2 3.18Å; L60-V62 PolarHBondContact O-N 3.17Å; V62-F104 HydrophobicContact CG1-CD1 4.29Å; V62-I106 HydrophobicContact CB-CD1 4.08Å; V62-I106 HydrophobicContact CG1-CD1 3.63Å; V62-I106 HydrophobicContact CG1-CG1 3.9Å; V62-I106 HydrophobicContact CG2-CD1 3.35Å; V62-I106 HydrophobicContact CG2-CG1 4.48Å
63	T	78.1	Confident	72.5	Confident	42 Å²	42	100.9 Å²	100.9	26%	0.258	54%	0.538	S	S	.	.	S	Bend	trans	-162.8	164.9	-173.4	-168.8	0	0	0	0	111.6	Y67 L68	T63-Y67 WeakPolarHBondContact OG1-CD2 3.28Å; T63-L68 HydrophobicContact CG2-CD1 4.05Å; T63-L68 HydrophobicContact CG2-CD2 3.42Å; T63-L68 VanDerWaalsContact CG2-CD2 3.42Å; T63-L68 HydrophobicContact CG2-CG 3.57Å
64	E	78.9	Confident	74.7	Confident	72 Å²	72	100.6 Å²	100.6	34%	0.336	53%	0.532	S	S	.	.			trans	-67.2	145.7	173.9	-58.8	177.6	-107.4	0	0	111.3	K66 Y67	E64-K66 HydrophobicContact CB-CD 4.5Å; E64-K66 HydrophobicContact CB-CG 4.13Å; E64-K66 VanDerWaalsContact CD-CE 3.47Å; E64-K66 PolarHBondContact O-N 3.43Å; E64-K66 VanDerWaalsContact O-N 3.07Å; E64-K66 VanDerWaalsContact OE1-CE 3.3Å; E64-K66 WeakPolarHBondContact OE1-CE 3.36Å; E64-K66 IonicContact OE1-NZ 2.86Å; E64-K66 PolarHBondContact OE1-NZ 3.38Å; E64-K66 VanDerWaalsContact OE2-CE 3.22Å; E64-K66 WeakPolarHBondContact OE2-CE 3.45Å; E64-K66 IonicContact OE2-NZ 2.65Å; E64-K66 PolarHBondContact OE2-NZ 3.09Å; E64-Y67 HydrophobicContact CB-CD2 3.89Å; E64-Y67 HydrophobicContact CB-CE2 4.16Å; E64-Y67 HydrophobicContact CG-CE2 4.37Å; E64-Y67 PolarHBondContact O-N 3.45Å; E64-Y67 WeakPolarHBondContact OE1-CE2 3.47Å
65	R	78.7	Confident	77.1	Confident	130 Å²	130	97.2 Å²	97.2	49%	0.491	50%	0.5	S	S	.	.	G	3₁₀ helix	trans	-56.4	-28.9	-179.6	-176.7	171.4	-174.8	151.3	3.8	114.5	K50 E51 Y67 L68	K50-R65 PolarHBondContact O-NH1 3.21Å; K50-R65 VanDerWaalsContact O-NH1 3.15Å; E51-R65 HydrophobicContact CB-CB 4.49Å; E51-R65 VanDerWaalsContact O-CB 3.24Å; E51-R65 WeakPolarHBondContact O-CB 3.22Å; E51-R65 WeakPolarHBondContact O-CD 3.02Å; R65-Y67 PolarHBondContact O-N 3.35Å; R65-L68 PolarHBondContact O-N 3.39Å; R65-L68 VanDerWaalsContact O-N 3.1Å; R65-L68 VanDerWaalsContact O-O 3.05Å
66	K	82.5	Confident	79.4	Confident	138 Å²	138	97.1 Å²	97.1	60%	0.6	49%	0.492	S	S	*	.	G	3₁₀ helix	trans	-63.7	-25.1	177.7	73.1	-168.4	-176.7	-153.9	0	113.5	E64	E64-K66 HydrophobicContact CB-CD 4.5Å; E64-K66 HydrophobicContact CB-CG 4.13Å; E64-K66 VanDerWaalsContact CD-CE 3.47Å; E64-K66 PolarHBondContact O-N 3.43Å; E64-K66 VanDerWaalsContact O-N 3.07Å; E64-K66 VanDerWaalsContact OE1-CE 3.3Å; E64-K66 WeakPolarHBondContact OE1-CE 3.36Å; E64-K66 IonicContact OE1-NZ 2.86Å; E64-K66 PolarHBondContact OE1-NZ 3.38Å; E64-K66 VanDerWaalsContact OE2-CE 3.22Å; E64-K66 WeakPolarHBondContact OE2-CE 3.45Å; E64-K66 IonicContact OE2-NZ 2.65Å; E64-K66 PolarHBondContact OE2-NZ 3.09Å
67	Y	80.8	Confident	81.5	Confident	127 Å²	127	95.2 Å²	95.2	50%	0.498	48%	0.476	S	S	.	.	G	3₁₀ helix	trans	-88.4	-18.1	176	-59.6	-62.6	0	0	0	112.3	T63 E64 R65	T63-Y67 WeakPolarHBondContact OG1-CD2 3.28Å; E64-Y67 HydrophobicContact CB-CD2 3.89Å; E64-Y67 HydrophobicContact CB-CE2 4.16Å; E64-Y67 HydrophobicContact CG-CE2 4.37Å; E64-Y67 PolarHBondContact O-N 3.45Å; E64-Y67 WeakPolarHBondContact OE1-CE2 3.47Å; R65-Y67 PolarHBondContact O-N 3.35Å
68	L	84.3	Confident	83.7	Confident	39 Å²	39	90 Å²	90	20%	0.204	45%	0.454	C	S	.	.	S	Bend	trans	-87.9	113.5	176.4	-61.5	179.6	0	0	0	110.4	L53 T63 R65 F104	L53-L68 HydrophobicContact CD1-CD1 3.88Å; T63-L68 HydrophobicContact CG2-CD1 4.05Å; T63-L68 HydrophobicContact CG2-CD2 3.42Å; T63-L68 VanDerWaalsContact CG2-CD2 3.42Å; T63-L68 HydrophobicContact CG2-CG 3.57Å; R65-L68 PolarHBondContact O-N 3.39Å; R65-L68 VanDerWaalsContact O-N 3.1Å; R65-L68 VanDerWaalsContact O-O 3.05Å; L68-F104 HydrophobicContact CD2-CE1 3.56Å; L68-F104 HydrophobicContact CD2-CZ 3.75Å
69	K	86.5	Confident	85.8	Confident	171 Å²	171	90.9 Å²	90.9	74%	0.743	45%	0.449	S	S	*	.	P	Polyproline II helix	trans	-74.5	140.8	168.7	-64.2	-156.6	177.4	-174.4	0	109.3	D71 N102	K69-D71 PolarHBondContact O-N 3.28Å; K69-N102 PolarHBondContact O-ND2 3.33Å
70	S	91.2	Very high	87.6	Confident	104 Å²	104	92 Å²	92	73%	0.727	45%	0.447	S	S	*	.	P	Polyproline II helix	trans	-65.1	131.8	174	-58.5	0	0	0	0	110.3
71	D	94.2	Very high	89.3	Confident	76 Å²	76	91 Å²	91	41%	0.406	45%	0.446	S	S	.	.	P	Polyproline II helix	trans	-57.3	141.4	170.2	-73.4	-6.6	0	0	0	110.3	K69 C101 N102 C157	K69-D71 PolarHBondContact O-N 3.28Å; D71-C101 WeakPolarHBondContact OD1-CA 3.46Å; D71-N102 VanDerWaalsContact OD1-CG 3.28Å; D71-N102 PolarHBondContact OD1-N 2.88Å; D71-N102 PolarHBondContact OD1-ND2 3.26Å; D71-C157 HydrophobicContact CB-CB 4.43Å
72	W	97.4	Very high	90.7	Very high	89 Å²	89	86.5 Å²	86.5	34%	0.337	42%	0.418	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-140	136.9	166.5	66.4	-89.6	0	0	0	109.8	K74 Y98 G99 Q100	W72-K74 HydrophobicContact CE3-CD 4.07Å; W72-K74 HydrophobicContact CE3-CG 4.05Å; W72-K74 HydrophobicContact CZ3-CD 4.02Å; W72-K74 HydrophobicContact CZ3-CG 4.28Å; W72-Y98 AromaticContact CH2-CD2 3.67Å; W72-Y98 HydrophobicContact CH2-CD2 3.67Å; W72-Y98 AromaticContact CH2-CE2 3.57Å; W72-Y98 HydrophobicContact CH2-CE2 3.57Å; W72-Y98 AromaticContact CZ3-CD2 3.7Å; W72-Y98 HydrophobicContact CZ3-CD2 3.7Å; W72-Y98 AromaticContact CZ3-CE2 3.5Å; W72-Y98 HydrophobicContact CZ3-CE2 3.5Å; W72-Y98 VanDerWaalsContact CZ3-CE2 3.5Å; W72-Y98 HydrophobicContact CZ3-CG 4.42Å; W72-G99 VanDerWaalsContact CZ3-CA 3.48Å; W72-G99 CarbonylContact O-C 3.55Å; W72-G99 WeakPolarHBondContact O-CA 3.41Å; W72-Q100 HydrophobicContact CZ2-CB 4.29Å; W72-Q100 HydrophobicContact CZ2-CG 3.73Å; W72-Q100 PolarHBondContact N-O 3.07Å; W72-Q100 PolarHBondContact O-N 3.19Å; W72-Q100 VanDerWaalsContact O-O 3.13Å
73	C	98.6	Very high	92	Very high	30 Å²	30	86.3 Å²	86.3	20%	0.203	42%	0.42	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-143.7	125.9	177.3	178.1	0	0	0	0	108.1	C123 R156	C73-C123 VanDerWaalsContact CA-SG 3.58Å; C73-C123 HydrophobicContact CB-CB 3.84Å; C73-C123 WeakPolarHBondContact CB-SG 3.38Å; C73-C123 VanDerWaalsContact SG-CA 3.52Å; C73-C123 WeakPolarHBondContact SG-CB 3.46Å; C73-C123 CovalentContact SG-SG 2.04Å; C73-C123 PolarHBondContact SG-SG 3.06Å; C73-R156 VanDerWaalsContact SG-CA 3.54Å; C73-R156 PolarHBondContact SG-N 3.23Å; C73-R156 VanDerWaalsContact SG-N 3.36Å
74	K	98.5	Very high	92.8	Very high	103 Å²	103	87.6 Å²	87.6	45%	0.448	42%	0.423	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-114.9	144.5	-172.1	-74.6	175.4	179.2	177.4	0	110.8	W72 C97 Y98	W72-K74 HydrophobicContact CE3-CD 4.07Å; W72-K74 HydrophobicContact CE3-CG 4.05Å; W72-K74 HydrophobicContact CZ3-CD 4.02Å; W72-K74 HydrophobicContact CZ3-CG 4.28Å; K74-C97 WeakPolarHBondContact O-CA 3.34Å; K74-Y98 HydrophobicContact CB-CD1 3.95Å; K74-Y98 HydrophobicContact CB-CE1 3.42Å; K74-Y98 VanDerWaalsContact CB-CE1 3.42Å; K74-Y98 HydrophobicContact CD-CE1 3.9Å; K74-Y98 HydrophobicContact CD-CE2 4.46Å; K74-Y98 WeakPolarHBondContact CD-OH 3.26Å; K74-Y98 HydrophobicContact CG-CE1 4.3Å; K74-Y98 PolarHBondContact N-O 3.34Å; K74-Y98 PolarHBondContact O-N 3.32Å
75	T	98.8	Very high	93.6	Very high	38 Å²	38	92.9 Å²	92.9	23%	0.233	45%	0.448	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-105.4	114.3	171.2	-47.2	0	0	0	0	108	R95 V152 C155	T75-R95 HydrophobicContact CG2-CB 3.76Å; T75-R95 HydrophobicContact CG2-CG 4.17Å; T75-V152 HydrophobicContact CG2-CG1 4.25Å; T75-C155 WeakPolarHBondContact OG1-CB 3.33Å; T75-C155 PolarHBondContact OG1-N 3.19Å; T75-C155 PolarHBondContact OG1-SG 3.43Å; T75-C155 VanDerWaalsContact OG1-SG 3.34Å
76	Q	98.6	Very high	94.4	Very high	74 Å²	74	89 Å²	89	35%	0.346	45%	0.449	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-116.9	144.9	-175.9	-71.2	-61.9	-60.1	0	0	112.2	R95 F96 Y98	Q76-R95 CarbonylContact O-C 3.24Å; Q76-R95 WeakPolarHBondContact O-CA 3.47Å; Q76-R95 VanDerWaalsContact O-CB 3.22Å; Q76-R95 WeakPolarHBondContact O-CB 2.95Å; Q76-F96 HydrophobicContact CB-CD1 3.81Å; Q76-F96 HydrophobicContact CB-CE1 3.31Å; Q76-F96 HydrophobicContact CB-CE2 4.35Å; Q76-F96 HydrophobicContact CB-CZ 3.62Å; Q76-F96 HydrophobicContact CG-CE1 4.35Å; Q76-F96 HydrophobicContact CG-CZ 4.21Å; Q76-F96 PolarHBondContact N-O 3.38Å; Q76-F96 WeakPolarHBondContact O-CD1 3.48Å; Q76-F96 PolarHBondContact O-N 3.46Å; Q76-Y98 HydrophobicContact CB-CE1 4.43Å; Q76-Y98 HydrophobicContact CG-CD1 3.99Å; Q76-Y98 HydrophobicContact CG-CE1 3.34Å
77	P	98.4	Very high	95.2	Very high	79 Å²	79	83.4 Å²	83.4	51%	0.513	43%	0.426	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-62.3	140.8	175	26.6	-33	0	0	0	111.5	L93	P77-L93 HydrophobicContact CB-CD1 3.75Å
78	L	97.9	Very high	96	Very high	79 Å²	79	84.3 Å²	84.3	41%	0.414	43%	0.429	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-134	131.2	173.7	178.2	63.2	0	0	0	109.2	Q80 N94 F96	L78-Q80 PolarHBondContact O-N 3.31Å; L78-N94 PolarHBondContact N-O 2.97Å; L78-N94 CarbonylContact O-C 3.47Å; L78-N94 PolarHBondContact O-N 3Å; L78-F96 HydrophobicContact CB-CD1 4.04Å
79	R	98	Very high	96.7	Very high	203 Å²	203	85.9 Å²	85.9	77%	0.766	44%	0.443	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-80.5	109.6	167.4	-68.8	178.6	69.2	136.8	0.4	108.1	T91	R79-T91 HydrophobicContact CB-CG2 3.89Å; R79-T91 HydrophobicContact CG-CG2 4.43Å
80	Q	97.7	Very high	97.2	Very high	66 Å²	66	84.3 Å²	84.3	31%	0.308	43%	0.432	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-107.4	128.2	178.4	-179	178.6	-2.8	0	0	109.2	L78 T91 I92 N94	L78-Q80 PolarHBondContact O-N 3.31Å; Q80-T91 WeakPolarHBondContact O-CA 3.12Å; Q80-I92 HydrophobicContact CB-CG1 4.35Å; Q80-I92 PolarHBondContact N-O 3.48Å; Q80-I92 PolarHBondContact O-N 3.21Å; Q80-N94 HydrophobicContact CB-CB 4.19Å; Q80-N94 PolarHBondContact OE1-ND2 3Å
81	T	97.9	Very high	97.5	Very high	84 Å²	84	82.5 Å²	82.5	52%	0.515	42%	0.417	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-88.1	132.6	173.7	-61.4	0	0	0	0	110	T91	T81-T91 PolarHBondContact OG1-OG1 3.46Å
82	V	98.1	Very high	97.6	Very high	4 Å²	4	80.1 Å²	80.1	2%	0.024	40%	0.404	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-108.8	119.3	177.5	-173.9	0	0	0	0	107.1	S89 R90 I92 V133 L135 K147 I149	V82-S89 CarbonylContact O-C 3.59Å; V82-S89 WeakPolarHBondContact O-CA 3.49Å; V82-S89 WeakPolarHBondContact O-CB 3.11Å; V82-R90 WeakPolarHBondContact CB-O 3.31Å; V82-R90 PolarHBondContact N-O 2.95Å; V82-R90 PolarHBondContact O-N 3.27Å; V82-I92 HydrophobicContact CG2-CD1 3.97Å; V82-I92 HydrophobicContact CG2-CG1 3.81Å; V82-I92 HydrophobicContact CG2-CG2 4.18Å; V82-V133 HydrophobicContact CG1-CG1 4.45Å; V82-V133 HydrophobicContact CG2-CG1 4.48Å; V82-L135 HydrophobicContact CB-CD2 4.32Å; V82-L135 HydrophobicContact CG1-CD1 4.22Å; V82-L135 HydrophobicContact CG1-CD2 4.08Å; V82-K147 HydrophobicContact CG1-CB 4.19Å; V82-K147 HydrophobicContact CG1-CD 3.69Å; V82-K147 HydrophobicContact CG1-CG 4.02Å; V82-I149 HydrophobicContact CB-CD1 3.85Å; V82-I149 HydrophobicContact CG1-CD1 3.39Å; V82-I149 HydrophobicContact CG1-CG1 4.49Å; V82-I149 HydrophobicContact CG2-CD1 3.11Å
83	S	96.9	Very high	97.6	Very high	65 Å²	65	80.1 Å²	80.1	46%	0.455	41%	0.41	S	S	.	.			trans	-124.9	151	-179.9	55.9	0	0	0	0	110.9	S89 K147	S83-S89 WeakPolarHBondContact CA-OG 3.1Å; S83-S89 WeakPolarHBondContact CB-OG 3.02Å; S83-K147 PolarHBondContact O-NZ 3Å
84	E	96	Very high	97.6	Very high	68 Å²	68	79.1 Å²	79.1	32%	0.318	40%	0.403	S	S	.	.			trans	-149.6	147.6	172.6	-170	163.1	162.4	0	0	107.9	C87 L135	E84-C87 HydrophobicContact CB-CB 4.19Å; E84-C87 PolarHBondContact O-N 3.46Å; E84-L135 HydrophobicContact CB-CD1 3.48Å; E84-L135 VanDerWaalsContact CB-CD1 3.48Å
85	E	95.1	Very high	97.6	Very high	184 Å²	184	78.2 Å²	78.2	86%	0.86	40%	0.397	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.1	139.2	-178.6	-171.3	177.3	-179.9	0	0	110.9	C87	E85-C87 PolarHBondContact O-N 3.48Å
86	G	96.1	Very high	97.6	Very high	49 Å²	49	80.6 Å²	80.6	51%	0.505	40%	0.404	S	S	.	.	T	Hydrogen-bonded Turn	trans	71.5	1.8	-177.1	0	0	0	0	0	114.9
87	C	97.8	Very high	97.6	Very high	19 Å²	19	78.6 Å²	78.6	13%	0.128	40%	0.398	C	S	.	.	S	Bend	trans	-118.7	149.5	-177.8	-55.2	0	0	0	0	112.7	E84 E85 S89 L135 E136 C137	E84-C87 HydrophobicContact CB-CB 4.19Å; E84-C87 PolarHBondContact O-N 3.46Å; E85-C87 PolarHBondContact O-N 3.48Å; C87-S89 PolarHBondContact O-N 3.38Å; C87-L135 HydrophobicContact CB-CB 3.97Å; C87-L135 HydrophobicContact CB-CD1 4.38Å; C87-E136 CarbonylContact C-O 3.56Å; C87-E136 VanDerWaalsContact CA-O 3.28Å; C87-E136 WeakPolarHBondContact CA-O 3.47Å; C87-C137 HydrophobicContact CB-CB 4Å; C87-C137 WeakPolarHBondContact CB-SG 3.02Å; C87-C137 WeakPolarHBondContact SG-CB 3.33Å; C87-C137 CovalentContact SG-SG 2.03Å; C87-C137 PolarHBondContact SG-SG 2.86Å
88	R	98.1	Very high	97.6	Very high	147 Å²	147	79 Å²	79	56%	0.555	39%	0.39	S	S	*	.			trans	-70.2	125.7	170.1	-67.6	-178.2	177.9	167.6	-1.1	109.6	E136	R88-E136 HydrophobicContact CB-CB 4.47Å; R88-E136 WeakPolarHBondContact CD-OE2 3.32Å; R88-E136 IonicContact CZ-OE1 3.5Å; R88-E136 IonicContact CZ-OE2 3.68Å; R88-E136 PolarHBondContact N-O 2.93Å; R88-E136 IonicContact NE-OE2 3.86Å; R88-E136 IonicContact NH1-OE1 2.91Å; R88-E136 PolarHBondContact NH1-OE1 2.91Å; R88-E136 IonicContact NH1-OE2 2.84Å; R88-E136 PolarHBondContact NH1-OE2 3.41Å
89	S	98.1	Very high	97.6	Very high	72 Å²	72	76.7 Å²	76.7	50%	0.503	39%	0.385	S	S	.	.			trans	-68.4	141.3	178.9	-65.2	0	0	0	0	111.2	V82 S83 C87	V82-S89 CarbonylContact O-C 3.59Å; V82-S89 WeakPolarHBondContact O-CA 3.49Å; V82-S89 WeakPolarHBondContact O-CB 3.11Å; S83-S89 WeakPolarHBondContact CA-OG 3.1Å; S83-S89 WeakPolarHBondContact CB-OG 3.02Å; C87-S89 PolarHBondContact O-N 3.38Å
90	R	97.5	Very high	97.5	Very high	137 Å²	137	73.1 Å²	73.1	52%	0.517	38%	0.377	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-120.4	132.1	179.9	-174.8	176.2	176.5	167.3	3.5	110.7	V82 I92 E134 L135	V82-R90 WeakPolarHBondContact CB-O 3.31Å; V82-R90 PolarHBondContact N-O 2.95Å; V82-R90 PolarHBondContact O-N 3.27Å; R90-I92 HydrophobicContact CG-CG2 4.47Å; R90-E134 PolarHBondContact NH1-O 3.06Å; R90-L135 HydrophobicContact CB-CD2 3.76Å
91	T	98	Very high	97.4	Very high	66 Å²	66	71.5 Å²	71.5	41%	0.405	37%	0.373	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-86.5	128.7	171	-54.9	0	0	0	0	110.4	R79 Q80 T81	R79-T91 HydrophobicContact CB-CG2 3.89Å; R79-T91 HydrophobicContact CG-CG2 4.43Å; Q80-T91 WeakPolarHBondContact O-CA 3.12Å; T81-T91 PolarHBondContact OG1-OG1 3.46Å
92	I	97.1	Very high	97.1	Very high	26 Å²	26	69.8 Å²	69.8	13%	0.133	36%	0.361	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-117.1	155.6	173.6	65.9	164	0	0	0	110.8	Q80 V82 R90 N94 V133 I149	Q80-I92 HydrophobicContact CB-CG1 4.35Å; Q80-I92 PolarHBondContact N-O 3.48Å; Q80-I92 PolarHBondContact O-N 3.21Å; V82-I92 HydrophobicContact CG2-CD1 3.97Å; V82-I92 HydrophobicContact CG2-CG1 3.81Å; V82-I92 HydrophobicContact CG2-CG2 4.18Å; R90-I92 HydrophobicContact CG-CG2 4.47Å; I92-N94 PolarHBondContact O-N 3.21Å; I92-V133 HydrophobicContact CD1-CG2 4.16Å; I92-V133 HydrophobicContact CG2-CG1 4.13Å; I92-V133 HydrophobicContact CG2-CG2 4.1Å; I92-I149 HydrophobicContact CD1-CD1 3.94Å; I92-I149 HydrophobicContact CD1-CG2 4.33Å
93	L	97.6	Very high	96.8	Very high	89 Å²	89	73.5 Å²	73.5	47%	0.466	39%	0.387	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-84.5	110.5	170.3	-175.3	65.9	0	0	0	109.9	P77 K151	P77-L93 HydrophobicContact CB-CD1 3.75Å; L93-K151 WeakPolarHBondContact O-CE 3.47Å; L93-K151 PolarHBondContact O-NZ 3Å
94	N	97.9	Very high	96.4	Very high	10 Å²	10	73.2 Å²	73.2	5%	0.053	38%	0.377	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-108.4	-170	167.8	-154.9	-12.9	0	0	0	110.2	L78 Q80 I92 Q150 K151 V152	L78-N94 PolarHBondContact N-O 2.97Å; L78-N94 CarbonylContact O-C 3.47Å; L78-N94 PolarHBondContact O-N 3Å; Q80-N94 HydrophobicContact CB-CB 4.19Å; Q80-N94 PolarHBondContact OE1-ND2 3Å; I92-N94 PolarHBondContact O-N 3.21Å; N94-Q150 PolarHBondContact ND2-O 3.32Å; N94-K151 VanDerWaalsContact OD1-CA 3.28Å; N94-K151 WeakPolarHBondContact OD1-CA 3.32Å; N94-V152 PolarHBondContact OD1-N 3.38Å
95	R	98.6	Very high	95.9	Very high	84 Å²	84	76.8 Å²	76.8	32%	0.317	39%	0.389	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-137.9	152.1	174.6	-58.3	-174.8	177.2	78.5	-0.5	111.3	T75 Q76 V152	T75-R95 HydrophobicContact CG2-CB 3.76Å; T75-R95 HydrophobicContact CG2-CG 4.17Å; Q76-R95 CarbonylContact O-C 3.24Å; Q76-R95 WeakPolarHBondContact O-CA 3.47Å; Q76-R95 VanDerWaalsContact O-CB 3.22Å; Q76-R95 WeakPolarHBondContact O-CB 2.95Å; R95-V152 HydrophobicContact CB-CB 4.05Å; R95-V152 HydrophobicContact CB-CG1 4.25Å; R95-V152 WeakPolarHBondContact O-CB 3.07Å; R95-V152 WeakPolarHBondContact O-CG2 3Å
96	F	98.2	Very high	95.4	Very high	87 Å²	87	69.5 Å²	69.5	38%	0.382	36%	0.355	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-120	161.2	172.2	74.5	-81.3	0	0	0	111	Q76 L78 Y98	Q76-F96 HydrophobicContact CB-CD1 3.81Å; Q76-F96 HydrophobicContact CB-CE1 3.31Å; Q76-F96 HydrophobicContact CB-CE2 4.35Å; Q76-F96 HydrophobicContact CB-CZ 3.62Å; Q76-F96 HydrophobicContact CG-CE1 4.35Å; Q76-F96 HydrophobicContact CG-CZ 4.21Å; Q76-F96 PolarHBondContact N-O 3.38Å; Q76-F96 WeakPolarHBondContact O-CD1 3.48Å; Q76-F96 PolarHBondContact O-N 3.46Å; L78-F96 HydrophobicContact CB-CD1 4.04Å; F96-Y98 HydrophobicContact CD2-CD1 4.44Å; F96-Y98 AromaticContact CE2-CD1 3.78Å; F96-Y98 HydrophobicContact CE2-CD1 3.78Å; F96-Y98 HydrophobicContact CE2-CG 4.15Å; F96-Y98 HydrophobicContact CZ-CD1 4.36Å
97	C	98.7	Very high	94.9	Very high	33 Å²	33	71.1 Å²	71.1	22%	0.223	36%	0.357	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-108.5	135.3	178.8	-58	0	0	0	0	110.3	K74 P125 C155	K74-C97 WeakPolarHBondContact O-CA 3.34Å; C97-P125 VanDerWaalsContact SG-N 3.41Å; C97-C155 WeakPolarHBondContact CA-SG 3.36Å; C97-C155 HydrophobicContact CB-CB 3.65Å; C97-C155 WeakPolarHBondContact CB-SG 3.44Å; C97-C155 WeakPolarHBondContact SG-CB 3.37Å; C97-C155 CovalentContact SG-SG 2.02Å; C97-C155 PolarHBondContact SG-SG 3.01Å
98	Y	98.2	Very high	94	Very high	87 Å²	87	76.2 Å²	76.2	34%	0.341	37%	0.373	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-151	146.5	168.8	81.1	-68.3	0	0	0	109.8	W72 K74 Q76 F96 C123	W72-Y98 AromaticContact CH2-CD2 3.67Å; W72-Y98 HydrophobicContact CH2-CD2 3.67Å; W72-Y98 AromaticContact CH2-CE2 3.57Å; W72-Y98 HydrophobicContact CH2-CE2 3.57Å; W72-Y98 AromaticContact CZ3-CD2 3.7Å; W72-Y98 HydrophobicContact CZ3-CD2 3.7Å; W72-Y98 AromaticContact CZ3-CE2 3.5Å; W72-Y98 HydrophobicContact CZ3-CE2 3.5Å; W72-Y98 VanDerWaalsContact CZ3-CE2 3.5Å; W72-Y98 HydrophobicContact CZ3-CG 4.42Å; K74-Y98 HydrophobicContact CB-CD1 3.95Å; K74-Y98 HydrophobicContact CB-CE1 3.42Å; K74-Y98 VanDerWaalsContact CB-CE1 3.42Å; K74-Y98 HydrophobicContact CD-CE1 3.9Å; K74-Y98 HydrophobicContact CD-CE2 4.46Å; K74-Y98 WeakPolarHBondContact CD-OH 3.26Å; K74-Y98 HydrophobicContact CG-CE1 4.3Å; K74-Y98 PolarHBondContact N-O 3.34Å; K74-Y98 PolarHBondContact O-N 3.32Å; Q76-Y98 HydrophobicContact CB-CE1 4.43Å; Q76-Y98 HydrophobicContact CG-CD1 3.99Å; Q76-Y98 HydrophobicContact CG-CE1 3.34Å; F96-Y98 HydrophobicContact CD2-CD1 4.44Å; F96-Y98 AromaticContact CE2-CD1 3.78Å; F96-Y98 HydrophobicContact CE2-CD1 3.78Å; F96-Y98 HydrophobicContact CE2-CG 4.15Å; F96-Y98 HydrophobicContact CZ-CD1 4.36Å; Y98-C123 PolarHBondContact O-SG 3.03Å
99	G	97.8	Very high	92.4	Very high	30 Å²	30	77.4 Å²	77.4	31%	0.309	39%	0.385	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-179.8	176.2	-168.7	0	0	0	0	0	113.6	W72	W72-G99 VanDerWaalsContact CZ3-CA 3.48Å; W72-G99 CarbonylContact O-C 3.55Å; W72-G99 WeakPolarHBondContact O-CA 3.41Å
100	Q	96.4	Very high	90.6	Very high	128 Å²	128	79.3 Å²	79.3	60%	0.598	39%	0.394	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-129.5	124.4	168.3	-66.4	175.1	-30.5	0	0	107.9	W72	W72-Q100 HydrophobicContact CZ2-CB 4.29Å; W72-Q100 HydrophobicContact CZ2-CG 3.73Å; W72-Q100 PolarHBondContact N-O 3.07Å; W72-Q100 PolarHBondContact O-N 3.19Å; W72-Q100 VanDerWaalsContact O-O 3.13Å
101	C	95.5	Very high	88.8	Confident	32 Å²	32	81.7 Å²	81.7	22%	0.216	41%	0.407	C	S	.	.			trans	-123	145.3	-179.2	-50.4	0	0	0	0	108.8	D71 A121 C123 C157	D71-C101 WeakPolarHBondContact OD1-CA 3.46Å; C101-A121 HydrophobicContact CB-CB 3.89Å; C101-A121 WeakPolarHBondContact CB-O 3.29Å; C101-C123 PolarHBondContact SG-N 2.76Å; C101-C123 VanDerWaalsContact SG-N 3.42Å; C101-C157 HydrophobicContact CB-CB 3.74Å; C101-C157 WeakPolarHBondContact CB-SG 3.5Å; C101-C157 WeakPolarHBondContact SG-CA 3.24Å; C101-C157 WeakPolarHBondContact SG-CB 3.47Å; C101-C157 CovalentContact SG-SG 2.04Å; C101-C157 PolarHBondContact SG-SG 3.1Å
102	N	91.9	Very high	87.1	Confident	49 Å²	49	89.2 Å²	89.2	26%	0.262	44%	0.435	S	S	.	.			trans	-72.1	149.6	177.1	-70.2	-62	0	0	0	111.9	K69 D71 F104	K69-N102 PolarHBondContact O-ND2 3.33Å; D71-N102 VanDerWaalsContact OD1-CG 3.28Å; D71-N102 PolarHBondContact OD1-N 2.88Å; D71-N102 PolarHBondContact OD1-ND2 3.26Å; N102-F104 HydrophobicContact CB-CE2 3.87Å; N102-F104 HydrophobicContact CB-CZ 3.94Å
103	S	91.3	Very high	85.6	Confident	82 Å²	82	96.9 Å²	96.9	57%	0.573	47%	0.47	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-132	152.2	166.7	61.1	0	0	0	0	109.5	S119	S103-S119 CarbonylContact C-O 3.49Å; S103-S119 VanDerWaalsContact CA-O 3.29Å; S103-S119 WeakPolarHBondContact CA-O 3.46Å
104	F	87.9	Confident	84	Confident	58 Å²	58	98.7 Å²	98.7	25%	0.254	48%	0.476	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-134.6	131.4	-175.9	-60.3	-77.6	0	0	0	109.7	V62 L68 N102 F117 Q118 S119	V62-F104 HydrophobicContact CG1-CD1 4.29Å; L68-F104 HydrophobicContact CD2-CE1 3.56Å; L68-F104 HydrophobicContact CD2-CZ 3.75Å; N102-F104 HydrophobicContact CB-CE2 3.87Å; N102-F104 HydrophobicContact CB-CZ 3.94Å; F104-F117 HydrophobicContact CB-CE1 4.22Å; F104-Q118 WeakPolarHBondContact O-CA 3.22Å; F104-S119 PolarHBondContact N-O 3.24Å; F104-S119 PolarHBondContact O-N 3.39Å
105	Y	87.3	Confident	82.9	Confident	144 Å²	144	106.5 Å²	106.5	57%	0.565	51%	0.512	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-126.3	116.4	166.3	179.4	-90.9	0	0	0	107.2	P107 S116 Q118	Y105-P107 HydrophobicContact CD1-CG 4.3Å; Y105-P107 HydrophobicContact CE1-CG 3.92Å; Y105-S116 WeakPolarHBondContact CE2-OG 3.43Å; Y105-S116 WeakPolarHBondContact OH-CB 3.29Å; Y105-S116 PolarHBondContact OH-OG 3.22Å; Y105-Q118 HydrophobicContact CD2-CG 4.36Å
106	I	84.5	Confident	82.1	Confident	30 Å²	30	104.4 Å²	104.4	15%	0.154	51%	0.51	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-120.2	108.8	-178.1	-52.5	170.7	0	0	0	107.4	L60 V62 R108 F117	L60-I106 HydrophobicContact CD2-CD1 3.57Å; L60-I106 HydrophobicContact CD2-CG2 4.23Å; L60-I106 HydrophobicContact CG-CD1 4.33Å; V62-I106 HydrophobicContact CB-CD1 4.08Å; V62-I106 HydrophobicContact CG1-CD1 3.63Å; V62-I106 HydrophobicContact CG1-CG1 3.9Å; V62-I106 HydrophobicContact CG2-CD1 3.35Å; V62-I106 HydrophobicContact CG2-CG1 4.48Å; I106-R108 PolarHBondContact O-N 3.28Å; I106-F117 HydrophobicContact CB-CB 4.22Å; I106-F117 HydrophobicContact CB-CD1 4.18Å; I106-F117 HydrophobicContact CD1-CD1 3.52Å; I106-F117 HydrophobicContact CD1-CE1 3.95Å; I106-F117 HydrophobicContact CD1-CG 4.4Å; I106-F117 HydrophobicContact CG1-CD1 3.89Å; I106-F117 PolarHBondContact N-O 3.34Å; I106-F117 PolarHBondContact O-N 3.43Å
107	P	84.3	Confident	81.4	Confident	83 Å²	83	104 Å²	104	54%	0.539	51%	0.508	S	S	.	.	P	Polyproline II helix	trans	-57.9	126	170.1	-18.2	29	0	0	0	109.2	Y105	Y105-P107 HydrophobicContact CD1-CG 4.3Å; Y105-P107 HydrophobicContact CE1-CG 3.92Å
108	R	79.2	Confident	80.7	Confident	126 Å²	126	107.6 Å²	107.6	48%	0.475	52%	0.522	S	S	.	.	P	Polyproline II helix	trans	-90.4	131.6	163	-67.8	-174.1	178.4	-170.5	3.3	107.5	I106 E114	I106-R108 PolarHBondContact O-N 3.28Å; R108-E114 IonicContact CZ-OE2 3.86Å; R108-E114 IonicContact NH1-OE2 2.79Å; R108-E114 PolarHBondContact NH1-OE2 3.21Å
109	H	65.2	Low	80.3	Confident	173 Å²	173	105.5 Å²	105.5	80%	0.801	52%	0.52	S	S	*	.	P	Polyproline II helix	trans	-82.1	141.8	158.3	-64.4	-59.7	0	0	0	107
110	V	59.3	Low	80	Confident	112 Å²	112	105.6 Å²	105.6	68%	0.679	52%	0.516	S	S	*	.	S	Bend	trans	123.8	125.4	154.4	-170.2	0	0	0	0	114.2
111	K	60.7	Low	79.9	Confident	186 Å²	186	100.5 Å²	100.5	81%	0.809	50%	0.496	S	S	*	.	S	Bend	trans	40.5	96.8	167.2	-64.9	177.5	-175	-177.7	0	116.8	E113	K111-E113 PolarHBondContact O-N 3.04Å
112	K	62.5	Low	79.9	Confident	225 Å²	225	105.3 Å²	105.3	98%	0.978	51%	0.513	S	S	*	.	T	Hydrogen-bonded Turn	trans	25.2	-18.8	157.4	-104.4	-174.8	-177.9	-175.7	0	123.6
113	E	64.4	Low	80.2	Confident	186 Å²	186	103.5 Å²	103.5	87%	0.869	50%	0.504	S	S	*	.	T	Hydrogen-bonded Turn	trans	-121.9	-10.4	-169.1	-68.7	-179.8	178.6	0	0	114.4	K111	K111-E113 PolarHBondContact O-N 3.04Å
114	E	64.9	Low	80.5	Confident	128 Å²	128	102.9 Å²	102.9	60%	0.598	49%	0.491	S	S	*	.	P	Polyproline II helix	trans	-95.1	117.8	171.5	-71.2	-168.7	-157.4	0	0	111.7	R108	R108-E114 IonicContact CZ-OE2 3.86Å; R108-E114 IonicContact NH1-OE2 2.79Å; R108-E114 PolarHBondContact NH1-OE2 3.21Å
115	E	75.4	Confident	81	Confident	174 Å²	174	102.8 Å²	102.8	81%	0.813	50%	0.496	S	S	*	.	P	Polyproline II helix	trans	-66.2	151.8	172.9	-64.8	-179.4	170.1	0	0	111.4
116	S	81.8	Confident	81.5	Confident	40 Å²	40	99.1 Å²	99.1	28%	0.28	48%	0.484	S	S	.	.	P	Polyproline II helix	trans	-55.7	141	171.6	52	0	0	0	0	110.8	Y105 Q118	Y105-S116 WeakPolarHBondContact CE2-OG 3.43Å; Y105-S116 WeakPolarHBondContact OH-CB 3.29Å; Y105-S116 PolarHBondContact OH-OG 3.22Å; S116-Q118 PolarHBondContact O-N 3.01Å
117	F	82.4	Confident	82.1	Confident	77 Å²	77	105 Å²	105	34%	0.338	51%	0.505	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-70.5	125.6	174.2	171	-89.9	0	0	0	109.6	F104 I106	F104-F117 HydrophobicContact CB-CE1 4.22Å; I106-F117 HydrophobicContact CB-CB 4.22Å; I106-F117 HydrophobicContact CB-CD1 4.18Å; I106-F117 HydrophobicContact CD1-CD1 3.52Å; I106-F117 HydrophobicContact CD1-CE1 3.95Å; I106-F117 HydrophobicContact CD1-CG 4.4Å; I106-F117 HydrophobicContact CG1-CD1 3.89Å; I106-F117 PolarHBondContact N-O 3.34Å; I106-F117 PolarHBondContact O-N 3.43Å
118	Q	85	Confident	82.8	Confident	110 Å²	110	104.3 Å²	104.3	51%	0.514	50%	0.498	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-131.5	130.6	178.1	-165.6	173.1	26.1	0	0	110.3	F104 Y105 S116 L162	F104-Q118 WeakPolarHBondContact O-CA 3.22Å; Y105-Q118 HydrophobicContact CD2-CG 4.36Å; S116-Q118 PolarHBondContact O-N 3.01Å; Q118-L162 HydrophobicContact CG-CD1 3.76Å
119	S	88.3	Confident	83.7	Confident	43 Å²	43	100.9 Å²	100.9	30%	0.301	49%	0.492	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-137.9	125.8	174.6	-173.5	0	0	0	0	109.1	S103 F104	S103-S119 CarbonylContact C-O 3.49Å; S103-S119 VanDerWaalsContact CA-O 3.29Å; S103-S119 WeakPolarHBondContact CA-O 3.46Å; F104-S119 PolarHBondContact N-O 3.24Å; F104-S119 PolarHBondContact O-N 3.39Å
120	C	92	Very high	85.2	Confident	32 Å²	32	95.9 Å²	95.9	22%	0.216	48%	0.476	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-131.2	137.1	178.3	-173.9	0	0	0	0	109.2	S159 V160 L162	C120-S159 CarbonylContact O-C 3.56Å; C120-S159 VanDerWaalsContact O-CA 3.26Å; C120-S159 WeakPolarHBondContact O-CA 3.49Å; C120-V160 HydrophobicContact CB-CG2 3.96Å; C120-V160 PolarHBondContact O-N 3.25Å; C120-L162 HydrophobicContact CB-CD1 4.01Å; C120-L162 HydrophobicContact CB-CD2 4.14Å; C120-L162 HydrophobicContact CB-CG 4.2Å
121	A	93.9	Very high	87	Confident	21 Å²	21	92.8 Å²	92.8	17%	0.174	46%	0.457	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-121	144.7	173.3	0	0	0	0	0	111	C101 C157 M158	C101-A121 HydrophobicContact CB-CB 3.89Å; C101-A121 WeakPolarHBondContact CB-O 3.29Å; A121-C157 HydrophobicContact CB-CB 4.48Å; A121-M158 CarbonylContact C-O 3.53Å; A121-M158 VanDerWaalsContact CA-O 3.26Å; A121-M158 WeakPolarHBondContact CA-O 3.19Å
122	F	95.7	Very high	88.8	Confident	132 Å²	132	89.5 Å²	89.5	58%	0.579	45%	0.448	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-125.6	141.6	178.1	-173.5	-108.4	0	0	0	110.7	K124 M158 V160	F122-K124 HydrophobicContact CD1-CB 3.82Å; F122-K124 HydrophobicContact CD1-CD 4.48Å; F122-K124 HydrophobicContact CD1-CG 4.43Å; F122-K124 HydrophobicContact CE1-CB 4.23Å; F122-K124 PolarHBondContact O-N 3.38Å; F122-K124 VanDerWaalsContact O-N 3.13Å; F122-M158 PolarHBondContact N-O 3.37Å; F122-M158 PolarHBondContact O-N 3.14Å; F122-V160 HydrophobicContact CB-CG1 3.96Å
123	C	98.1	Very high	90.5	Very high	11 Å²	11	79.2 Å²	79.2	7%	0.074	40%	0.404	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-78.8	95.7	176.6	176.2	0	0	0	0	109.6	C73 Y98 C101	C73-C123 VanDerWaalsContact CA-SG 3.58Å; C73-C123 HydrophobicContact CB-CB 3.84Å; C73-C123 WeakPolarHBondContact CB-SG 3.38Å; C73-C123 VanDerWaalsContact SG-CA 3.52Å; C73-C123 WeakPolarHBondContact SG-CB 3.46Å; C73-C123 CovalentContact SG-SG 2.04Å; C73-C123 PolarHBondContact SG-SG 3.06Å; Y98-C123 PolarHBondContact O-SG 3.03Å; C101-C123 PolarHBondContact SG-N 2.76Å; C101-C123 VanDerWaalsContact SG-N 3.42Å
124	K	97.5	Very high	92.1	Very high	70 Å²	70	75.7 Å²	75.7	30%	0.304	39%	0.388	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-129.2	167.5	-175.7	61.2	-178.8	-178.1	180	0	113.1	F122 Q126 C155 R156 M158	F122-K124 HydrophobicContact CD1-CB 3.82Å; F122-K124 HydrophobicContact CD1-CD 4.48Å; F122-K124 HydrophobicContact CD1-CG 4.43Å; F122-K124 HydrophobicContact CE1-CB 4.23Å; F122-K124 PolarHBondContact O-N 3.38Å; F122-K124 VanDerWaalsContact O-N 3.13Å; K124-Q126 PolarHBondContact O-N 3.47Å; K124-Q126 VanDerWaalsContact O-N 3.13Å; K124-C155 VanDerWaalsContact O-CA 3.31Å; K124-C155 WeakPolarHBondContact O-CA 3.42Å; K124-R156 PolarHBondContact N-O 3.09Å; K124-R156 PolarHBondContact O-N 3.48Å; K124-M158 HydrophobicContact CG-CB 4.28Å; K124-M158 HydrophobicContact CG-SD 4.13Å
125	P	98.1	Very high	93.6	Very high	56 Å²	56	69.7 Å²	69.7	36%	0.364	36%	0.36	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-58.2	117.2	174.4	-25.1	35.3	0	0	0	111.3	C97 V128 V152 Q154	C97-P125 VanDerWaalsContact SG-N 3.41Å; P125-V128 HydrophobicContact CB-CG2 3.4Å; P125-V128 HydrophobicContact CG-CG2 4.37Å; P125-V152 HydrophobicContact CB-CG1 4.09Å; P125-V152 HydrophobicContact CB-CG2 4.15Å; P125-V152 HydrophobicContact CG-CG1 4.25Å; P125-V152 HydrophobicContact CG-CG2 3.81Å; P125-Q154 CarbonylContact C-O 3.54Å; P125-Q154 WeakPolarHBondContact CA-O 3.26Å
126	Q	97.6	Very high	94.7	Very high	67 Å²	67	66.1 Å²	66.1	31%	0.313	34%	0.343	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-82.6	-36.8	171.1	-172.8	-168.8	8.1	0	0	110.7	K124 Q154 R156 M158	K124-Q126 PolarHBondContact O-N 3.47Å; K124-Q126 VanDerWaalsContact O-N 3.13Å; Q126-Q154 PolarHBondContact N-O 3.31Å; Q126-R156 HydrophobicContact CB-CB 4.01Å; Q126-R156 HydrophobicContact CG-CB 4.37Å; Q126-M158 HydrophobicContact CB-SD 3.98Å; Q126-M158 HydrophobicContact CG-SD 4.1Å
127	R	98.4	Very high	95.5	Very high	153 Å²	153	64.2 Å²	64.2	58%	0.577	33%	0.33	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-128.1	121.6	179.3	-64.5	-178.9	179.8	164.7	-6.1	109.5	K153 Q154	R127-K153 HydrophobicContact CB-CB 3.95Å; R127-K153 WeakPolarHBondContact O-CB 3.41Å; R127-K153 PolarHBondContact O-N 2.85Å; R127-Q154 HydrophobicContact CB-CB 4.07Å; R127-Q154 HydrophobicContact CG-CB 4.31Å; R127-Q154 PolarHBondContact N-O 3.02Å; R127-Q154 VanDerWaalsContact N-O 3.15Å; R127-Q154 VanDerWaalsContact NH1-OE1 3.11Å; R127-Q154 PolarHBondContact O-N 2.89Å
128	V	98.5	Very high	96.2	Very high	68 Å²	68	64.7 Å²	64.7	41%	0.412	34%	0.34	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-125.7	143.1	176.6	-174.9	0	0	0	0	108.6	P125 Q150 K151	P125-V128 HydrophobicContact CB-CG2 3.4Å; P125-V128 HydrophobicContact CG-CG2 4.37Å; V128-Q150 HydrophobicContact CG1-CB 3.96Å; V128-Q150 HydrophobicContact CG1-CG 4.32Å; V128-K151 WeakPolarHBondContact CA-O 3.42Å
129	T	97.8	Very high	96.7	Very high	55 Å²	55	62.9 Å²	62.9	34%	0.337	35%	0.351	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-128.4	148	173.7	55.2	0	0	0	0	109.2	K151 K153	T129-K151 PolarHBondContact N-O 3.14Å; T129-K151 PolarHBondContact O-N 3.07Å; T129-K151 PolarHBondContact OG1-O 3.22Å; T129-K153 HydrophobicContact CG2-CD 4.46Å; T129-K153 HydrophobicContact CG2-CG 3.87Å; T129-K153 WeakPolarHBondContact OG1-CE 3.31Å
130	S	98	Very high	97	Very high	68 Å²	68	63.7 Å²	63.7	48%	0.476	35%	0.352	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-89.8	139.1	168.3	-64.8	0	0	0	0	110.3	K148 I149	S130-K148 VanDerWaalsContact CB-CE 3.41Å; S130-K148 VanDerWaalsContact OG-CE 3.32Å; S130-K148 WeakPolarHBondContact OG-CE 3.31Å; S130-I149 CarbonylContact C-O 3.35Å; S130-I149 WeakPolarHBondContact CA-O 3.21Å
131	V	96.5	Very high	97.2	Very high	46 Å²	46	69.4 Å²	69.4	28%	0.279	38%	0.38	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-125.8	142.1	172.6	-63.6	0	0	0	0	109.5	V133 K148 I149 K151	V131-V133 HydrophobicContact CG2-CG2 4.34Å; V131-K148 WeakPolarHBondContact O-CA 3.31Å; V131-I149 HydrophobicContact CG2-CB 4.37Å; V131-I149 PolarHBondContact N-O 3.17Å; V131-I149 PolarHBondContact O-N 3.2Å; V131-K151 HydrophobicContact CG1-CB 4.45Å; V131-K151 HydrophobicContact CG1-CD 4.4Å; V131-K151 HydrophobicContact CG2-CB 4.39Å
132	L	97.8	Very high	97.3	Very high	117 Å²	117	70.8 Å²	70.8	61%	0.613	39%	0.388	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-89.3	126.4	168.8	-66.5	175.3	0	0	0	108.3	K148	L132-K148 HydrophobicContact CD2-CB 3.82Å; L132-K148 HydrophobicContact CD2-CG 4.21Å
133	V	97.8	Very high	97.4	Very high	10 Å²	10	68.1 Å²	68.1	6%	0.061	38%	0.384	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-108.5	117.3	175.7	-179.6	0	0	0	0	107.5	V82 I92 V131 L135 K147 I149	V82-V133 HydrophobicContact CG1-CG1 4.45Å; V82-V133 HydrophobicContact CG2-CG1 4.48Å; I92-V133 HydrophobicContact CD1-CG2 4.16Å; I92-V133 HydrophobicContact CG2-CG1 4.13Å; I92-V133 HydrophobicContact CG2-CG2 4.1Å; V131-V133 HydrophobicContact CG2-CG2 4.34Å; V133-L135 HydrophobicContact CG1-CD2 4.1Å; V133-K147 PolarHBondContact N-O 2.9Å; V133-K147 PolarHBondContact O-N 3.28Å; V133-I149 HydrophobicContact CB-CD1 4.18Å; V133-I149 HydrophobicContact CG2-CD1 3.63Å; V133-I149 HydrophobicContact CG2-CG1 4.16Å
134	E	97.8	Very high	97.3	Very high	112 Å²	112	71.7 Å²	71.7	52%	0.523	40%	0.398	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-77.8	127.1	170.7	-166.2	179.4	119.3	0	0	110.2	R90 F144 R145 L146	R90-E134 PolarHBondContact NH1-O 3.06Å; E134-F144 HydrophobicContact CG-CB 4.09Å; E134-F144 HydrophobicContact CG-CD2 4.27Å; E134-F144 HydrophobicContact CG-CG 4.47Å; E134-R145 WeakPolarHBondContact CA-O 3.34Å; E134-L146 HydrophobicContact CB-CD2 3.75Å; E134-L146 HydrophobicContact CG-CD2 3.92Å
135	L	98.4	Very high	97.3	Very high	2 Å²	2	73 Å²	73	1%	0.01	40%	0.401	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-109.2	139.2	174.4	-58.1	178.7	0	0	0	108.9	V82 E84 C87 R90 V133 C137 F144 R145 K147	V82-L135 HydrophobicContact CB-CD2 4.32Å; V82-L135 HydrophobicContact CG1-CD1 4.22Å; V82-L135 HydrophobicContact CG1-CD2 4.08Å; E84-L135 HydrophobicContact CB-CD1 3.48Å; E84-L135 VanDerWaalsContact CB-CD1 3.48Å; C87-L135 HydrophobicContact CB-CB 3.97Å; C87-L135 HydrophobicContact CB-CD1 4.38Å; R90-L135 HydrophobicContact CB-CD2 3.76Å; V133-L135 HydrophobicContact CG1-CD2 4.1Å; L135-C137 PolarHBondContact O-SG 2.65Å; L135-C137 VanDerWaalsContact O-SG 3.41Å; L135-F144 CarbonylContact O-C 3.59Å; L135-F144 WeakPolarHBondContact O-CA 3.37Å; L135-F144 WeakPolarHBondContact O-CB 3.44Å; L135-R145 PolarHBondContact N-O 3.32Å; L135-R145 PolarHBondContact O-N 2.96Å; L135-K147 HydrophobicContact CD1-CB 4.31Å; L135-K147 HydrophobicContact CD1-CD 4.39Å
136	E	98.3	Very high	97.3	Very high	99 Å²	99	74.8 Å²	74.8	46%	0.463	41%	0.407	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-82.8	126	176.2	-173.9	-168.2	167.7	0	0	109.4	C87 R88	C87-E136 CarbonylContact C-O 3.56Å; C87-E136 VanDerWaalsContact CA-O 3.28Å; C87-E136 WeakPolarHBondContact CA-O 3.47Å; R88-E136 HydrophobicContact CB-CB 4.47Å; R88-E136 WeakPolarHBondContact CD-OE2 3.32Å; R88-E136 IonicContact CZ-OE1 3.5Å; R88-E136 IonicContact CZ-OE2 3.68Å; R88-E136 PolarHBondContact N-O 2.93Å; R88-E136 IonicContact NE-OE2 3.86Å; R88-E136 IonicContact NH1-OE1 2.91Å; R88-E136 PolarHBondContact NH1-OE1 2.91Å; R88-E136 IonicContact NH1-OE2 2.84Å; R88-E136 PolarHBondContact NH1-OE2 3.41Å
137	C	97.8	Very high	97.2	Very high	0 Å²	0	75.3 Å²	75.3	0%	0	41%	0.408	C	S	.	.			trans	-130.7	75.4	-173.2	-45.5	0	0	0	0	110.3	C87 L135 G139 L140 P143 R145	C87-C137 HydrophobicContact CB-CB 4Å; C87-C137 WeakPolarHBondContact CB-SG 3.02Å; C87-C137 WeakPolarHBondContact SG-CB 3.33Å; C87-C137 CovalentContact SG-SG 2.03Å; C87-C137 PolarHBondContact SG-SG 2.86Å; L135-C137 PolarHBondContact O-SG 2.65Å; L135-C137 VanDerWaalsContact O-SG 3.41Å; C137-G139 PolarHBondContact O-N 3.25Å; C137-L140 HydrophobicContact CB-CB 4.03Å; C137-L140 HydrophobicContact CB-CD1 3.77Å; C137-L140 HydrophobicContact CB-CG 3.97Å; C137-L140 PolarHBondContact O-N 3.48Å; C137-P143 PolarHBondContact N-O 2.98Å; C137-P143 CarbonylContact O-C 3.49Å; C137-P143 WeakPolarHBondContact O-CA 3.3Å; C137-R145 WeakPolarHBondContact SG-CG 3.22Å; C137-R145 PolarHBondContact SG-N 3.31Å; C137-R145 VanDerWaalsContact SG-N 3.4Å
138	P	96.5	Very high	97.2	Very high	86 Å²	86	75.1 Å²	75.1	56%	0.558	41%	0.412	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.5	-17.5	-167.6	25.5	-35.1	0	0	0	114.8
139	G	95.5	Very high	97.1	Very high	72 Å²	72	72.7 Å²	72.7	74%	0.742	40%	0.396	S	S	*	.	T	Hydrogen-bonded Turn	trans	-97.1	3	176.8	0	0	0	0	0	114.9	C137	C137-G139 PolarHBondContact O-N 3.25Å
140	L	95.5	Very high	97.1	Very high	60 Å²	60	76.8 Å²	76.8	31%	0.314	41%	0.411	S	S	.	.	S	Bend	trans	-112.6	156.9	-178.1	-56.9	-175.5	0	0	0	111	C137 P142 P143 R145	C137-L140 HydrophobicContact CB-CB 4.03Å; C137-L140 HydrophobicContact CB-CD1 3.77Å; C137-L140 HydrophobicContact CB-CG 3.97Å; C137-L140 PolarHBondContact O-N 3.48Å; L140-P142 CarbonylContact C-O 3.44Å; L140-P142 CarbonylContact O-C 3.51Å; L140-P142 VanDerWaalsContact O-C 3.24Å; L140-P143 VanDerWaalsContact O-CA 3.29Å; L140-P143 WeakPolarHBondContact O-CA 3.48Å; L140-R145 HydrophobicContact CD1-CG 4.2Å
141	D	95.8	Very high	97.1	Very high	152 Å²	152	75.6 Å²	75.6	81%	0.813	40%	0.398	S	S	*	.	S	Bend	trans	-118.1	116.5	166.8	-174	30.9	0	0	0	109.2
142	P	95.6	Very high	97.2	Very high	51 Å²	51	74.2 Å²	74.2	33%	0.331	39%	0.39	S	S	.	.	S	Bend	cis	-68.2	161.1	-1.7	31.5	-36.6	0	0	0	112.5	L140 F144	L140-P142 CarbonylContact C-O 3.44Å; L140-P142 CarbonylContact O-C 3.51Å; L140-P142 VanDerWaalsContact O-C 3.24Å; P142-F144 HydrophobicContact CB-CD1 3.98Å; P142-F144 HydrophobicContact CB-CE1 3.72Å; P142-F144 HydrophobicContact CB-CZ 4.3Å; P142-F144 HydrophobicContact CG-CE1 4.25Å; P142-F144 HydrophobicContact CG-CZ 4.37Å; P142-F144 PolarHBondContact O-N 2.84Å
143	P	97.3	Very high	97.2	Very high	76 Å²	76	73.3 Å²	73.3	49%	0.494	38%	0.381	S	S	.	.	S	Bend	trans	-76.4	26	-175.8	33	-37.6	0	0	0	113.7	C137 L140	C137-P143 PolarHBondContact N-O 2.98Å; C137-P143 CarbonylContact O-C 3.49Å; C137-P143 WeakPolarHBondContact O-CA 3.3Å; L140-P143 VanDerWaalsContact O-CA 3.29Å; L140-P143 WeakPolarHBondContact O-CA 3.48Å
144	F	97.7	Very high	97.2	Very high	86 Å²	86	76.1 Å²	76.1	38%	0.377	39%	0.393	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-150.7	156.1	177.6	67.3	-89.6	0	0	0	111.9	E134 L135 P142 L146	E134-F144 HydrophobicContact CG-CB 4.09Å; E134-F144 HydrophobicContact CG-CD2 4.27Å; E134-F144 HydrophobicContact CG-CG 4.47Å; L135-F144 CarbonylContact O-C 3.59Å; L135-F144 WeakPolarHBondContact O-CA 3.37Å; L135-F144 WeakPolarHBondContact O-CB 3.44Å; P142-F144 HydrophobicContact CB-CD1 3.98Å; P142-F144 HydrophobicContact CB-CE1 3.72Å; P142-F144 HydrophobicContact CB-CZ 4.3Å; P142-F144 HydrophobicContact CG-CE1 4.25Å; P142-F144 HydrophobicContact CG-CZ 4.37Å; P142-F144 PolarHBondContact O-N 2.84Å; F144-L146 HydrophobicContact CD2-CG 4.37Å; F144-L146 HydrophobicContact CE2-CG 4.35Å
145	R	97.5	Very high	97.3	Very high	97 Å²	97	71.2 Å²	71.2	37%	0.366	37%	0.371	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-129.5	142	170.7	-67.3	-68	-178.3	-167.7	-3	110.1	E134 L135 C137 L140	E134-R145 WeakPolarHBondContact CA-O 3.34Å; L135-R145 PolarHBondContact N-O 3.32Å; L135-R145 PolarHBondContact O-N 2.96Å; C137-R145 WeakPolarHBondContact SG-CG 3.22Å; C137-R145 PolarHBondContact SG-N 3.31Å; C137-R145 VanDerWaalsContact SG-N 3.4Å; L140-R145 HydrophobicContact CD1-CG 4.2Å
146	L	97.1	Very high	97.3	Very high	94 Å²	94	78.2 Å²	78.2	49%	0.492	40%	0.397	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-103	110.3	176.6	-66	176.5	0	0	0	109.8	E134 F144	E134-L146 HydrophobicContact CB-CD2 3.75Å; E134-L146 HydrophobicContact CG-CD2 3.92Å; F144-L146 HydrophobicContact CD2-CG 4.37Å; F144-L146 HydrophobicContact CE2-CG 4.35Å
147	K	96.8	Very high	97.3	Very high	77 Å²	77	74.5 Å²	74.5	34%	0.335	38%	0.382	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-100.9	121.4	179.3	-172.6	149.8	178.5	164.6	0	111.4	V82 S83 V133 L135 I149	V82-K147 HydrophobicContact CG1-CB 4.19Å; V82-K147 HydrophobicContact CG1-CD 3.69Å; V82-K147 HydrophobicContact CG1-CG 4.02Å; S83-K147 PolarHBondContact O-NZ 3Å; V133-K147 PolarHBondContact N-O 2.9Å; V133-K147 PolarHBondContact O-N 3.28Å; L135-K147 HydrophobicContact CD1-CB 4.31Å; L135-K147 HydrophobicContact CD1-CD 4.39Å; K147-I149 HydrophobicContact CG-CD1 4.48Å; K147-I149 HydrophobicContact CG-CG1 4.19Å
148	K	97.2	Very high	97.2	Very high	150 Å²	150	77.6 Å²	77.6	65%	0.652	40%	0.397	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-80.6	128.1	175.6	-169.8	177.9	-178.5	178.4	0	110.7	S130 V131 L132	S130-K148 VanDerWaalsContact CB-CE 3.41Å; S130-K148 VanDerWaalsContact OG-CE 3.32Å; S130-K148 WeakPolarHBondContact OG-CE 3.31Å; V131-K148 WeakPolarHBondContact O-CA 3.31Å; L132-K148 HydrophobicContact CD2-CB 3.82Å; L132-K148 HydrophobicContact CD2-CG 4.21Å
149	I	96.9	Very high	97	Very high	17 Å²	17	78 Å²	78	9%	0.087	40%	0.402	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-133.4	141.1	-177.2	-47.7	-175.8	0	0	0	110.3	V82 I92 S130 V131 V133 K147	V82-I149 HydrophobicContact CB-CD1 3.85Å; V82-I149 HydrophobicContact CG1-CD1 3.39Å; V82-I149 HydrophobicContact CG1-CG1 4.49Å; V82-I149 HydrophobicContact CG2-CD1 3.11Å; I92-I149 HydrophobicContact CD1-CD1 3.94Å; I92-I149 HydrophobicContact CD1-CG2 4.33Å; S130-I149 CarbonylContact C-O 3.35Å; S130-I149 WeakPolarHBondContact CA-O 3.21Å; V131-I149 HydrophobicContact CG2-CB 4.37Å; V131-I149 PolarHBondContact N-O 3.17Å; V131-I149 PolarHBondContact O-N 3.2Å; V133-I149 HydrophobicContact CB-CD1 4.18Å; V133-I149 HydrophobicContact CG2-CD1 3.63Å; V133-I149 HydrophobicContact CG2-CG1 4.16Å; K147-I149 HydrophobicContact CG-CD1 4.48Å; K147-I149 HydrophobicContact CG-CG1 4.19Å
150	Q	97.5	Very high	96.7	Very high	140 Å²	140	76.3 Å²	76.3	65%	0.654	38%	0.377	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-80	125.9	171.2	-69.5	-172	-23.9	0	0	111	N94 V128	N94-Q150 PolarHBondContact ND2-O 3.32Å; V128-Q150 HydrophobicContact CG1-CB 3.96Å; V128-Q150 HydrophobicContact CG1-CG 4.32Å
151	K	97.6	Very high	96	Very high	43 Å²	43	78.7 Å²	78.7	19%	0.187	39%	0.39	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-112.3	121.2	177.1	-176.4	162	-180	155.8	0	110.7	L93 N94 V128 T129 V131	L93-K151 WeakPolarHBondContact O-CE 3.47Å; L93-K151 PolarHBondContact O-NZ 3Å; N94-K151 VanDerWaalsContact OD1-CA 3.28Å; N94-K151 WeakPolarHBondContact OD1-CA 3.32Å; V128-K151 WeakPolarHBondContact CA-O 3.42Å; T129-K151 PolarHBondContact N-O 3.14Å; T129-K151 PolarHBondContact O-N 3.07Å; T129-K151 PolarHBondContact OG1-O 3.22Å; V131-K151 HydrophobicContact CG1-CB 4.45Å; V131-K151 HydrophobicContact CG1-CD 4.4Å; V131-K151 HydrophobicContact CG2-CB 4.39Å
152	V	98.6	Very high	94.9	Very high	18 Å²	18	74.4 Å²	74.4	11%	0.109	37%	0.367	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-75	129.2	174.8	178.1	0	0	0	0	109.2	T75 N94 R95 P125	T75-V152 HydrophobicContact CG2-CG1 4.25Å; N94-V152 PolarHBondContact OD1-N 3.38Å; R95-V152 HydrophobicContact CB-CB 4.05Å; R95-V152 HydrophobicContact CB-CG1 4.25Å; R95-V152 WeakPolarHBondContact O-CB 3.07Å; R95-V152 WeakPolarHBondContact O-CG2 3Å; P125-V152 HydrophobicContact CB-CG1 4.09Å; P125-V152 HydrophobicContact CB-CG2 4.15Å; P125-V152 HydrophobicContact CG-CG1 4.25Å; P125-V152 HydrophobicContact CG-CG2 3.81Å
153	K	98.3	Very high	93.7	Very high	97 Å²	97	76.4 Å²	76.4	42%	0.422	38%	0.382	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-103.1	-40.6	177.2	-64	-69.6	-178.4	157.4	0	111.8	R127 T129	R127-K153 HydrophobicContact CB-CB 3.95Å; R127-K153 WeakPolarHBondContact O-CB 3.41Å; R127-K153 PolarHBondContact O-N 2.85Å; T129-K153 HydrophobicContact CG2-CD 4.46Å; T129-K153 HydrophobicContact CG2-CG 3.87Å; T129-K153 WeakPolarHBondContact OG1-CE 3.31Å
154	Q	98.6	Very high	91.9	Very high	70 Å²	70	78 Å²	78	33%	0.327	39%	0.387	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-152.3	144	-175.9	-173.5	172.4	6.7	0	0	110.6	P125 Q126 R127	P125-Q154 CarbonylContact C-O 3.54Å; P125-Q154 WeakPolarHBondContact CA-O 3.26Å; Q126-Q154 PolarHBondContact N-O 3.31Å; R127-Q154 HydrophobicContact CB-CB 4.07Å; R127-Q154 HydrophobicContact CG-CB 4.31Å; R127-Q154 PolarHBondContact N-O 3.02Å; R127-Q154 VanDerWaalsContact N-O 3.15Å; R127-Q154 VanDerWaalsContact NH1-OE1 3.11Å; R127-Q154 PolarHBondContact O-N 2.89Å
155	C	98.7	Very high	89.9	Confident	8 Å²	8	77.1 Å²	77.1	5%	0.054	39%	0.391	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-116	148	176	-51.7	0	0	0	0	109.9	T75 C97 K124	T75-C155 WeakPolarHBondContact OG1-CB 3.33Å; T75-C155 PolarHBondContact OG1-N 3.19Å; T75-C155 PolarHBondContact OG1-SG 3.43Å; T75-C155 VanDerWaalsContact OG1-SG 3.34Å; C97-C155 WeakPolarHBondContact CA-SG 3.36Å; C97-C155 HydrophobicContact CB-CB 3.65Å; C97-C155 WeakPolarHBondContact CB-SG 3.44Å; C97-C155 WeakPolarHBondContact SG-CB 3.37Å; C97-C155 CovalentContact SG-SG 2.02Å; C97-C155 PolarHBondContact SG-SG 3.01Å; K124-C155 VanDerWaalsContact O-CA 3.31Å; K124-C155 WeakPolarHBondContact O-CA 3.42Å
156	R	98.3	Very high	87.8	Confident	149 Å²	149	79.7 Å²	79.7	56%	0.562	41%	0.412	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-150.9	153.4	175.3	-165.2	-179.7	172.9	161.2	-0.2	110.3	C73 K124 Q126 M158	C73-R156 VanDerWaalsContact SG-CA 3.54Å; C73-R156 PolarHBondContact SG-N 3.23Å; C73-R156 VanDerWaalsContact SG-N 3.36Å; K124-R156 PolarHBondContact N-O 3.09Å; K124-R156 PolarHBondContact O-N 3.48Å; Q126-R156 HydrophobicContact CB-CB 4.01Å; Q126-R156 HydrophobicContact CG-CB 4.37Å; R156-M158 HydrophobicContact CB-CG 4.17Å; R156-M158 PolarHBondContact O-N 3.17Å
157	C	97.7	Very high	85.5	Confident	22 Å²	22	84.6 Å²	84.6	15%	0.149	43%	0.43	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-65	119.1	161.3	-70.1	0	0	0	0	108.8	D71 C101 A121	D71-C157 HydrophobicContact CB-CB 4.43Å; C101-C157 HydrophobicContact CB-CB 3.74Å; C101-C157 WeakPolarHBondContact CB-SG 3.5Å; C101-C157 WeakPolarHBondContact SG-CA 3.24Å; C101-C157 WeakPolarHBondContact SG-CB 3.47Å; C101-C157 CovalentContact SG-SG 2.04Å; C101-C157 PolarHBondContact SG-SG 3.1Å; A121-C157 HydrophobicContact CB-CB 4.48Å
158	M	95.7	Very high	82.7	Confident	65 Å²	65	92.8 Å²	92.8	32%	0.32	47%	0.469	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-133.2	139.4	-176.8	-65.4	177.6	67.8	0	0	109.6	A121 F122 K124 Q126 R156	A121-M158 CarbonylContact C-O 3.53Å; A121-M158 VanDerWaalsContact CA-O 3.26Å; A121-M158 WeakPolarHBondContact CA-O 3.19Å; F122-M158 PolarHBondContact N-O 3.37Å; F122-M158 PolarHBondContact O-N 3.14Å; K124-M158 HydrophobicContact CG-CB 4.28Å; K124-M158 HydrophobicContact CG-SD 4.13Å; Q126-M158 HydrophobicContact CB-SD 3.98Å; Q126-M158 HydrophobicContact CG-SD 4.1Å; R156-M158 HydrophobicContact CB-CG 4.17Å; R156-M158 PolarHBondContact O-N 3.17Å
159	S	93.4	Very high	82	Confident	94 Å²	94	89.9 Å²	89.9	66%	0.657	46%	0.46	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-59.1	143.3	177.9	-48	0	0	0	0	111.6	C120	C120-S159 CarbonylContact O-C 3.56Å; C120-S159 VanDerWaalsContact O-CA 3.26Å; C120-S159 WeakPolarHBondContact O-CA 3.49Å
160	V	88.9	Confident	81.2	Confident	36 Å²	36	93.7 Å²	93.7	22%	0.218	48%	0.479	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-126.2	141.9	175.3	-64.6	0	0	0	0	109.5	C120 F122 L162	C120-V160 HydrophobicContact CB-CG2 3.96Å; C120-V160 PolarHBondContact O-N 3.25Å; F122-V160 HydrophobicContact CB-CG1 3.96Å; V160-L162 HydrophobicContact CG2-CD2 4.45Å
161	N	81.8	Confident	80.3	Confident	110 Å²	110	91.2 Å²	91.2	59%	0.588	47%	0.47	S	S	*	.			trans	-83	123.6	169.5	-62.6	-33.1	0	0	0	108	S163 D164	N161-S163 VanDerWaalsContact C-N 3.25Å; N161-S163 PolarHBondContact O-N 3.04Å; N161-D164 PolarHBondContact O-N 3.37Å
162	L	71	Confident	79.3	Confident	63 Å²	63	94 Å²	94	33%	0.33	49%	0.486	S	S	.	.	G	3₁₀ helix	trans	-75.3	-19.2	-178.7	-66	167.8	0	0	0	112.2	Q118 C120 V160 D164 S165	Q118-L162 HydrophobicContact CG-CD1 3.76Å; C120-L162 HydrophobicContact CB-CD1 4.01Å; C120-L162 HydrophobicContact CB-CD2 4.14Å; C120-L162 HydrophobicContact CB-CG 4.2Å; V160-L162 HydrophobicContact CG2-CD2 4.45Å; L162-D164 PolarHBondContact O-N 3.23Å; L162-D164 VanDerWaalsContact O-N 3.14Å; L162-S165 PolarHBondContact O-N 2.79Å
163	S	70.4	Confident	78.1	Confident	93 Å²	93	98.8 Å²	98.8	65%	0.65	51%	0.51	S	S	*	.	G	3₁₀ helix	trans	-57.2	-25.4	172	58.6	0	0	0	0	114	N161	N161-S163 VanDerWaalsContact C-N 3.25Å; N161-S163 PolarHBondContact O-N 3.04Å
164	D	61.2	Low	76.7	Confident	109 Å²	109	98.9 Å²	98.9	58%	0.583	52%	0.516	S	S	*	.	G	3₁₀ helix	trans	-93	-11.6	-174.7	-57.6	-24.9	0	0	0	112.4	N161 L162	N161-D164 PolarHBondContact O-N 3.37Å; L162-D164 PolarHBondContact O-N 3.23Å; L162-D164 VanDerWaalsContact O-N 3.14Å
165	S	55.5	Low	75.1	Confident	67 Å²	67	100.9 Å²	100.9	47%	0.469	53%	0.529	S	S	.	.	G	3₁₀ helix	trans	-87.3	-16.8	-170.5	-58.5	0	0	0	0	114.2	L162 K167	L162-S165 PolarHBondContact O-N 2.79Å; S165-K167 PolarHBondContact O-N 2.64Å
166	D	52.8	Low	73.3	Confident	152 Å²	152	108.1 Å²	108.1	81%	0.813	57%	0.566	S	S	*	*	G	3₁₀ helix	trans	-79.3	4.3	177.4	-70	-31.4	0	0	0	113.8
167	K	47.9	Very low	71.3	Confident	197 Å²	197	104.7 Å²	104.7	86%	0.857	57%	0.566	S	S	*	*	G	3₁₀ helix	trans	-105.8	19.6	-178.8	-73	-171.1	179	179.4	0	114.7	S165	S165-K167 PolarHBondContact O-N 2.64Å
168	Q	38.7	Very low	68.8	Low	248 Å²	248	112.2 Å²	112.2	100%	1.159	60%	0.604	S	S	*	*			trans	-130.4	0	179.3	-153.4	148.5	41.4	0	0	111.8

Retrieved 168 of 168 residues in 25.9 ms (Link to these results)

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