S45A2_HUMAN Loading...

Membrane-associated transporter protein

Proton-associated glucose and sucrose transporter (By similarity). May be able to transport also fructose (By similarity). Expressed at a late melanosome maturation stage where functions as proton/glucose exporter which increase lumenal pH by decreasing glycolysis^1,2. Regulates melanogenesis by maintaining melanosome neutralization that is initially initiated by transient OCA2 and required for a proper function of the tyrosinase TYR^3,4.

AlphaFold DB , UniProt , Accession Q9UMX9, Species HUMAN (Homo sapiens, Human), Gene SLC45A2, Length 530 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	38.9	Very low	35.2	Very low	254 Å²	254	146.5 Å²	146.5	100%	1.251	88%	0.881	S	S	*	*				0	127.3	0	-82.7	165.6	152	0	0	107.9
2	G	39.1	Very low	35.2	Very low	80 Å²	80	148.2 Å²	148.2	83%	0.825	88%	0.879	S	S	*	*			trans	112.1	67.9	158	0	0	0	0	0	119
3	S	36.1	Very low	35	Very low	122 Å²	122	151.8 Å²	151.8	85%	0.853	87%	0.87	S	S	*	*			trans	72.7	109.1	135	-150.7	0	0	0	0	122.8
4	N	34.1	Very low	34.6	Very low	151 Å²	151	154.9 Å²	154.9	81%	0.807	87%	0.869	S	S	*	*			trans	-45.8	151.9	146.7	-80.2	-28	0	0	0	113.8
5	S	37.6	Very low	34.4	Very low	120 Å²	120	152.5 Å²	152.5	84%	0.839	87%	0.867	S	S	*	*				170.9	124.1	99.9	45.8	0	0	0	0	113.6
6	G	33.6	Very low	34.2	Very low	75 Å²	75	154.3 Å²	154.3	77%	0.773	87%	0.872	S	S	*	*			trans	76.3	103.5	130.4	0	0	0	0	0	120
7	Q	36.7	Very low	34.2	Very low	203 Å²	203	151.1 Å²	151.1	95%	0.949	87%	0.869	S	S	*	*				-168.9	118.9	107.1	-113.2	173.2	-14	0	0	111.7
8	A	32.4	Very low	34.1	Very low	108 Å²	108	151 Å²	151	89%	0.893	87%	0.865	S	S	*	*			trans	-74.2	136.9	168.7	0	0	0	0	0	110
9	G	33.1	Very low	34.1	Very low	72 Å²	72	152.2 Å²	152.2	74%	0.742	87%	0.868	S	S	*	*			trans	151.7	68	167.3	0	0	0	0	0	114.9
10	R	33.7	Very low	33.9	Very low	248 Å²	248	146.9 Å²	146.9	94%	0.936	85%	0.848	S	S	*	*			trans	-167.2	73.2	157.5	-111.5	169.6	-167.5	-169.5	3.8	111.8
11	H	31.9	Very low	33.9	Very low	178 Å²	178	145.8 Å²	145.8	82%	0.824	85%	0.846	S	S	*	*			trans	-121	77.6	156.3	-98.8	-78.4	0	0	0	107.7
12	I	35.9	Very low	33.9	Very low	167 Å²	167	141.6 Å²	141.6	86%	0.856	82%	0.821	S	S	*	*			trans	-133.3	92	159	-61.3	-175.9	0	0	0	107.2
13	Y	32.5	Very low	33.7	Very low	195 Å²	195	143.9 Å²	143.9	77%	0.765	81%	0.814	S	S	*	*			trans	-8.2	115.1	156.7	-80.6	-103.5	0	0	0	118.4
14	K	29	Very low	34.3	Very low	195 Å²	195	142.5 Å²	142.5	85%	0.848	81%	0.805	S	S	*	*				52.6	91	107.1	-154.4	178.3	-167	179	0	117.4
15	S	30.9	Very low	35.5	Very low	120 Å²	120	141.9 Å²	141.9	84%	0.839	81%	0.806	S	S	*	*			trans	176.4	84.5	143.2	-177.9	0	0	0	0	110.3
16	L	32.5	Very low	36.8	Very low	181 Å²	181	141.7 Å²	141.7	95%	0.948	79%	0.792	S	S	*	*			trans	-158.4	29.6	177.2	-112	167.7	0	0	0	113.4
17	A	32.9	Very low	38.6	Very low	99 Å²	99	140.2 Å²	140.2	82%	0.818	77%	0.769	S	S	*	*	S	Bend	trans	-141.3	28.5	-171.5	0	0	0	0	0	115.9
18	D	32.9	Very low	40.5	Very low	150 Å²	150	134.5 Å²	134.5	80%	0.802	75%	0.749	S	S	*	*			trans	-145.1	38.5	-179.3	-138.5	16.7	0	0	0	114.9
19	D	33.8	Very low	42.7	Very low	174 Å²	174	136.4 Å²	136.4	93%	0.93	74%	0.737	S	S	*	*			trans	-100.9	85.9	169.3	-79.2	-36.8	0	0	0	109.8
20	G	31.6	Very low	45.2	Very low	45 Å²	45	135.4 Å²	135.4	46%	0.464	71%	0.711	S	S	.	*			trans	-83.6	145.8	165.2	0	0	0	0	0	111.2	F22	G20-F22 PolarHBondContact O-N 3.32Å
21	P	33.5	Very low	47.8	Very low	124 Å²	124	126.4 Å²	126.4	81%	0.805	69%	0.685	S	S	*	*	T	Hydrogen-bonded Turn	trans	-75.4	15	-164.5	-12.6	28.8	0	0	0	116.8
22	F	38.2	Very low	50.5	Low	167 Å²	167	121.2 Å²	121.2	73%	0.732	67%	0.666	S	S	*	*	T	Hydrogen-bonded Turn	trans	-140.4	12.9	-168.4	-80	-78.7	0	0	0	116.2	G20 S24	G20-F22 PolarHBondContact O-N 3.32Å; F22-S24 PolarHBondContact O-N 3.33Å
23	D	35.8	Very low	53.1	Low	127 Å²	127	116.7 Å²	116.7	68%	0.679	65%	0.649	S	S	*	*			trans	-70.3	109.2	173.7	-80.5	-16.5	0	0	0	110.2	V25	D23-V25 PolarHBondContact O-N 3.42Å
24	S	48.8	Very low	55.9	Low	93 Å²	93	112.6 Å²	112.6	65%	0.65	63%	0.632	S	S	*	*			trans	-54.6	103.4	168	54.9	0	0	0	0	108	F22 E26	F22-S24 PolarHBondContact O-N 3.33Å; S24-E26 PolarHBondContact O-N 3.37Å
25	V	57.4	Low	58.9	Low	138 Å²	138	103.4 Å²	103.4	84%	0.836	59%	0.592	S	S	*	*			trans	-54.1	102.5	-177.7	-179.7	0	0	0	0	108.7	D23	D23-V25 PolarHBondContact O-N 3.42Å
26	E	66	Low	61.8	Low	117 Å²	117	100.4 Å²	100.4	55%	0.547	57%	0.566	S	S	.	*	P	Polyproline II helix	trans	-61.6	132.7	178.3	-165.2	179	-178.2	0	0	108	S24 H173	S24-E26 PolarHBondContact O-N 3.37Å; E26-H173 WeakPolarHBondContact OE1-CB 3.37Å; E26-H173 PolarHBondContact OE1-N 3.26Å
27	P	71.1	Confident	64.7	Low	43 Å²	43	95 Å²	95	28%	0.279	54%	0.537	S	S	.	.	P	Polyproline II helix	trans	-56.7	142.2	179.3	20.5	-32.3	0	0	0	110.5	C171 S172	P27-C171 WeakPolarHBondContact CG-O 3.28Å; P27-S172 WeakPolarHBondContact O-CB 3.49Å
28	P	75.9	Confident	67.6	Low	83 Å²	83	90.2 Å²	90.2	54%	0.539	50%	0.498	S	S	.	.	P	Polyproline II helix	trans	-62.2	146.6	-174.4	25.5	-34.7	0	0	0	111.1	R30	P28-R30 VanDerWaalsContact O-CD 3.31Å; P28-R30 WeakPolarHBondContact O-CD 3.42Å; P28-R30 PolarHBondContact O-N 3.25Å; P28-R30 PolarHBondContact O-NE 3.13Å
29	K	80.6	Confident	70.5	Confident	148 Å²	148	83.1 Å²	83.1	64%	0.643	46%	0.459	S	S	*	.	P	Polyproline II helix	trans	-53.5	136.1	176.3	-68.3	-170.9	-178.6	-170.5	0	110.9	Q174 D175	K29-Q174 VanDerWaalsContact NZ-OE1 3.15Å; K29-D175 VanDerWaalsContact CA-OD2 3.27Å; K29-D175 WeakPolarHBondContact CA-OD2 3.48Å
30	R	84.6	Confident	73.4	Confident	52 Å²	52	76.7 Å²	76.7	20%	0.196	42%	0.424	C	S	.	.	P	Polyproline II helix	trans	-100.6	138.1	-176.1	-56.3	-55.4	-173.7	178.9	1.5	110.3	P28 L35 V170 D175 I237	P28-R30 VanDerWaalsContact O-CD 3.31Å; P28-R30 WeakPolarHBondContact O-CD 3.42Å; P28-R30 PolarHBondContact O-N 3.25Å; P28-R30 PolarHBondContact O-NE 3.13Å; R30-L35 HydrophobicContact CB-CD2 4.41Å; R30-L35 HydrophobicContact CB-CG 4.5Å; R30-V170 PolarHBondContact NE-O 2.87Å; R30-V170 PolarHBondContact NH2-O 3.37Å; R30-V170 VanDerWaalsContact NH2-O 3.14Å; R30-D175 PolarHBondContact N-OD2 3.3Å; R30-I237 HydrophobicContact CG-CD1 4.43Å
31	P	88.7	Confident	76.5	Confident	59 Å²	59	74.5 Å²	74.5	38%	0.383	40%	0.402	S	S	.	.	P	Polyproline II helix	trans	-65.1	145.5	173.4	28.8	-34.9	0	0	0	110.1	S33 R34 L35	P31-S33 PolarHBondContact O-N 3.45Å; P31-S33 VanDerWaalsContact O-N 3.16Å; P31-R34 HydrophobicContact CG-CB 4.15Å; P31-R34 HydrophobicContact CG-CG 3.81Å; P31-R34 PolarHBondContact O-N 3.08Å; P31-L35 PolarHBondContact O-N 3.35Å
32	T	88.7	Confident	79.4	Confident	69 Å²	69	68.7 Å²	68.7	42%	0.423	36%	0.364	S	S	.	.	H	α-helix	trans	-54.2	-36.4	-178.6	-52.5	0	0	0	0	113.2	R34 L35 I36 Y182	T32-R34 VanDerWaalsContact C-N 3.27Å; T32-R34 PolarHBondContact O-N 2.76Å; T32-L35 WeakPolarHBondContact O-CB 3.25Å; T32-L35 PolarHBondContact O-N 3.43Å; T32-L35 VanDerWaalsContact O-N 3.14Å; T32-I36 HydrophobicContact CG2-CD1 3.98Å; T32-I36 HydrophobicContact CG2-CG1 4.38Å; T32-I36 WeakPolarHBondContact O-CG1 3.34Å; T32-I36 PolarHBondContact O-N 3.5Å; T32-Y182 HydrophobicContact CG2-CE2 3.82Å; T32-Y182 WeakPolarHBondContact CG2-OH 3.46Å
33	S	90.7	Very high	82.1	Confident	71 Å²	71	61.8 Å²	61.8	50%	0.497	33%	0.334	S	S	.	.	H	α-helix	trans	-58.6	-38.6	177.4	56.2	0	0	0	0	112.6	P31 I36 M37	P31-S33 PolarHBondContact O-N 3.45Å; P31-S33 VanDerWaalsContact O-N 3.16Å; S33-I36 PolarHBondContact O-N 3.28Å; S33-M37 VanDerWaalsContact O-CG 3.27Å; S33-M37 WeakPolarHBondContact O-CG 3.44Å; S33-M37 PolarHBondContact O-N 3.21Å
34	R	91.4	Very high	85	Confident	110 Å²	110	55.8 Å²	55.8	42%	0.415	30%	0.302	S	S	.	.	H	α-helix	trans	-71.5	-35.3	177.4	-72.3	-175.2	-170	165.9	1.1	112.1	P31 T32 M37 H38 I237	P31-R34 HydrophobicContact CG-CB 4.15Å; P31-R34 HydrophobicContact CG-CG 3.81Å; P31-R34 PolarHBondContact O-N 3.08Å; T32-R34 VanDerWaalsContact C-N 3.27Å; T32-R34 PolarHBondContact O-N 2.76Å; R34-M37 PolarHBondContact O-N 3.23Å; R34-H38 VanDerWaalsContact O-CB 3.32Å; R34-H38 WeakPolarHBondContact O-CB 3.44Å; R34-H38 PolarHBondContact O-N 3.42Å; R34-I237 HydrophobicContact CB-CD1 4.28Å; R34-I237 HydrophobicContact CB-CG1 3.9Å
35	L	90.7	Very high	87.2	Confident	1 Å²	1	52 Å²	52	1%	0.005	27%	0.273	C	S	.	.	H	α-helix	trans	-65.1	-41.3	173.2	-64.7	175.5	0	0	0	111.2	R30 P31 T32 H38 S39 L167 C171 D175 K178 Y182	R30-L35 HydrophobicContact CB-CD2 4.41Å; R30-L35 HydrophobicContact CB-CG 4.5Å; P31-L35 PolarHBondContact O-N 3.35Å; T32-L35 WeakPolarHBondContact O-CB 3.25Å; T32-L35 PolarHBondContact O-N 3.43Å; T32-L35 VanDerWaalsContact O-N 3.14Å; L35-H38 WeakPolarHBondContact O-CB 3.41Å; L35-H38 PolarHBondContact O-N 3.11Å; L35-S39 PolarHBondContact O-N 3.1Å; L35-S39 PolarHBondContact O-OG 3.28Å; L35-L167 HydrophobicContact CD2-CD1 4.12Å; L35-C171 VanDerWaalsContact CD2-SG 3.55Å; L35-D175 HydrophobicContact CD1-CB 4.33Å; L35-K178 HydrophobicContact CD1-CB 4.09Å; L35-Y182 HydrophobicContact CB-CD2 4.01Å; L35-Y182 HydrophobicContact CB-CE2 4.4Å; L35-Y182 HydrophobicContact CD1-CE2 4.48Å
36	I	93	Very high	88.9	Confident	58 Å²	58	46.7 Å²	46.7	30%	0.297	24%	0.239	S	C	.	.	H	α-helix	trans	-62.4	-49.2	174.5	-69.4	169	0	0	0	110.7	T32 S33 H38 S39 M40 Y182 F186	T32-I36 HydrophobicContact CG2-CD1 3.98Å; T32-I36 HydrophobicContact CG2-CG1 4.38Å; T32-I36 WeakPolarHBondContact O-CG1 3.34Å; T32-I36 PolarHBondContact O-N 3.5Å; S33-I36 PolarHBondContact O-N 3.28Å; I36-H38 PolarHBondContact O-N 3.25Å; I36-S39 WeakPolarHBondContact O-CA 3.46Å; I36-S39 WeakPolarHBondContact O-CB 3.3Å; I36-S39 PolarHBondContact O-N 3.42Å; I36-M40 PolarHBondContact O-N 3.46Å; I36-Y182 HydrophobicContact CD1-CE1 4.4Å; I36-Y182 HydrophobicContact CG1-CD1 4.08Å; I36-Y182 HydrophobicContact CG1-CE1 4.08Å; I36-Y182 HydrophobicContact CG1-CG 4.42Å; I36-F186 HydrophobicContact CB-CE2 4.38Å; I36-F186 HydrophobicContact CG1-CE2 4.27Å; I36-F186 HydrophobicContact CG2-CE2 3.8Å; I36-F186 HydrophobicContact CG2-CZ 3.66Å
37	M	93.7	Very high	90.3	Very high	66 Å²	66	41.8 Å²	41.8	33%	0.325	22%	0.216	S	C	.	.	H	α-helix	trans	-57.7	-39.6	175.6	-71.3	174.6	72.6	0	0	111.9	S33 R34 S39 M40 V232 H233	S33-M37 VanDerWaalsContact O-CG 3.27Å; S33-M37 WeakPolarHBondContact O-CG 3.44Å; S33-M37 PolarHBondContact O-N 3.21Å; R34-M37 PolarHBondContact O-N 3.23Å; M37-S39 VanDerWaalsContact C-N 3.29Å; M37-S39 PolarHBondContact O-N 3.3Å; M37-M40 WeakPolarHBondContact O-CB 3.5Å; M37-M40 PolarHBondContact O-N 2.85Å; M37-V232 HydrophobicContact CB-CG1 3.76Å; M37-V232 HydrophobicContact CE-CG1 4.07Å; M37-V232 HydrophobicContact CG-CG1 3.82Å; M37-H233 WeakPolarHBondContact O-CA 3.27Å
38	H	93	Very high	91.4	Very high	0 Å²	0	39.7 Å²	39.7	0%	0	20%	0.203	C	C	.	.	H	α-helix	trans	-64.9	-34.2	175	-162.9	104.1	0	0	0	111.8	R34 L35 I36 M40 Y166 H183 H233 S236	R34-H38 VanDerWaalsContact O-CB 3.32Å; R34-H38 WeakPolarHBondContact O-CB 3.44Å; R34-H38 PolarHBondContact O-N 3.42Å; L35-H38 WeakPolarHBondContact O-CB 3.41Å; L35-H38 PolarHBondContact O-N 3.11Å; I36-H38 PolarHBondContact O-N 3.25Å; H38-M40 PolarHBondContact O-N 3.26Å; H38-Y166 AromaticContact CE1-CD1 3.25Å; H38-Y166 WeakPolarHBondContact CE1-CD1 3.17Å; H38-Y166 AromaticContact CE1-CE1 3.45Å; H38-Y166 VanDerWaalsContact CE1-CE1 3.45Å; H38-Y166 WeakPolarHBondContact CE1-CE1 3.31Å; H38-Y166 AromaticContact CE1-CG 3.62Å; H38-Y166 AromaticContact CE1-CZ 3.96Å; H38-Y166 AromaticContact ND1-CE1 3.97Å; H38-Y166 AromaticContact NE2-CD1 3.85Å; H38-H183 AromaticContact CD2-CE1 3.93Å; H38-H183 AromaticContact CD2-NE2 3.35Å; H38-H183 PolarHBondContact CD2-NE2 3.32Å; H38-H233 AromaticContact CD2-CE1 3.61Å; H38-H233 AromaticContact CD2-ND1 3.91Å; H38-H233 AromaticContact CE1-CE1 3.69Å; H38-H233 AromaticContact CG-CE1 3.88Å; H38-H233 AromaticContact CG-ND1 3.92Å; H38-H233 AromaticContact ND1-CE1 3.9Å; H38-H233 AromaticContact NE2-CE1 3.49Å; H38-H233 PolarHBondContact NE2-CE1 3.22Å; H38-H233 PolarHBondContact O-ND1 3.01Å; H38-S236 PolarHBondContact ND1-OG 3.19Å
39	S	93.6	Very high	92.2	Very high	0 Å²	0	38 Å²	38	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-73.4	-15.7	179.8	-53.6	0	0	0	0	113.4	L35 I36 M37 A41 M42 F43 Y182 H183	L35-S39 PolarHBondContact O-N 3.1Å; L35-S39 PolarHBondContact O-OG 3.28Å; I36-S39 WeakPolarHBondContact O-CA 3.46Å; I36-S39 WeakPolarHBondContact O-CB 3.3Å; I36-S39 PolarHBondContact O-N 3.42Å; M37-S39 VanDerWaalsContact C-N 3.29Å; M37-S39 PolarHBondContact O-N 3.3Å; S39-A41 PolarHBondContact O-N 2.92Å; S39-M42 WeakPolarHBondContact O-CB 3.1Å; S39-M42 PolarHBondContact O-N 3.01Å; S39-F43 PolarHBondContact O-N 3.41Å; S39-Y182 WeakPolarHBondContact OG-CB 3.47Å; S39-H183 PolarHBondContact OG-CD2 3.29Å
40	M	95.7	Very high	92.6	Very high	39 Å²	39	31 Å²	31	19%	0.192	16%	0.156	C	C	.	.	H	α-helix	trans	-60.4	-28.6	-179.5	-67.1	-53.7	-51	0	0	113.5	I36 M37 H38 M42 F43 G44 F186 C229 V232	I36-M40 PolarHBondContact O-N 3.46Å; M37-M40 WeakPolarHBondContact O-CB 3.5Å; M37-M40 PolarHBondContact O-N 2.85Å; H38-M40 PolarHBondContact O-N 3.26Å; M40-M42 VanDerWaalsContact C-N 3.3Å; M40-M42 PolarHBondContact O-N 3.26Å; M40-F43 HydrophobicContact CE-CB 4.2Å; M40-F43 HydrophobicContact CE-CD1 4.05Å; M40-F43 HydrophobicContact CE-CG 4.14Å; M40-F43 WeakPolarHBondContact O-CB 3.28Å; M40-F43 PolarHBondContact O-N 3.23Å; M40-G44 PolarHBondContact O-N 3.49Å; M40-F186 HydrophobicContact SD-CD1 4.08Å; M40-F186 HydrophobicContact SD-CE1 3.86Å; M40-F186 HydrophobicContact SD-CZ 4.45Å; M40-C229 HydrophobicContact CB-CB 4.33Å; M40-C229 WeakPolarHBondContact CE-SG 3.48Å; M40-C229 VanDerWaalsContact O-CB 3.24Å; M40-C229 WeakPolarHBondContact O-CB 3.44Å; M40-C229 PolarHBondContact O-SG 2.98Å; M40-V232 HydrophobicContact CB-CB 4.41Å; M40-V232 HydrophobicContact CB-CG1 4.18Å; M40-V232 HydrophobicContact CG-CB 4.41Å; M40-V232 HydrophobicContact CG-CG1 3.77Å
41	A	94.7	Very high	92.9	Very high	0 Å²	0	28.5 Å²	28.5	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-63.1	-37.8	174.5	0	0	0	0	0	112.2	S39 G44 R45 I163 F230 H233	S39-A41 PolarHBondContact O-N 2.92Å; A41-G44 PolarHBondContact O-N 3.09Å; A41-R45 VanDerWaalsContact O-CB 3.3Å; A41-R45 WeakPolarHBondContact O-CB 3.17Å; A41-R45 PolarHBondContact O-N 3.49Å; A41-I163 HydrophobicContact CB-CD1 3.69Å; A41-I163 HydrophobicContact CB-CG1 4.37Å; A41-F230 HydrophobicContact CB-CE2 4.42Å; A41-H233 HydrophobicContact CB-CB 3.71Å; A41-H233 VanDerWaalsContact CB-CG 3.47Å
42	M	94.4	Very high	92.9	Very high	2 Å²	2	26 Å²	26	1%	0.01	13%	0.129	C	C	.	.	H	α-helix	trans	-67.1	-40	176	-63	-65.8	-74.7	0	0	111.2	S39 M40 E46 D160 I163 H183	S39-M42 WeakPolarHBondContact O-CB 3.1Å; S39-M42 PolarHBondContact O-N 3.01Å; M40-M42 VanDerWaalsContact C-N 3.3Å; M40-M42 PolarHBondContact O-N 3.26Å; M42-E46 WeakPolarHBondContact O-CB 3.44Å; M42-E46 PolarHBondContact O-N 2.94Å; M42-D160 VanDerWaalsContact CE-OD1 3.27Å; M42-D160 WeakPolarHBondContact CE-OD1 3.45Å; M42-I163 HydrophobicContact CG-CG2 4.24Å; M42-I163 HydrophobicContact SD-CD1 4.42Å; M42-I163 HydrophobicContact SD-CG2 4.01Å; M42-H183 HydrophobicContact CE-CB 4.39Å; M42-H183 HydrophobicContact CG-CB 3.87Å
43	F	96.3	Very high	92.7	Very high	22 Å²	22	24.6 Å²	24.6	10%	0.096	13%	0.125	C	C	.	.	H	α-helix	trans	-57.7	-52.3	172	177.6	-84.7	0	0	0	111.7	S39 M40 R45 E46 F47 F186 F189 G190 L193 V225 C229	S39-F43 PolarHBondContact O-N 3.41Å; M40-F43 HydrophobicContact CE-CB 4.2Å; M40-F43 HydrophobicContact CE-CD1 4.05Å; M40-F43 HydrophobicContact CE-CG 4.14Å; M40-F43 WeakPolarHBondContact O-CB 3.28Å; M40-F43 PolarHBondContact O-N 3.23Å; F43-R45 PolarHBondContact O-N 3.04Å; F43-E46 PolarHBondContact O-N 3.39Å; F43-F47 VanDerWaalsContact O-CB 3.25Å; F43-F47 WeakPolarHBondContact O-CB 3.31Å; F43-F47 PolarHBondContact O-N 2.8Å; F43-F186 WeakPolarHBondContact CA-O 3.2Å; F43-F186 HydrophobicContact CB-CB 4.05Å; F43-F186 HydrophobicContact CB-CD1 4.19Å; F43-F186 HydrophobicContact CD2-CD1 4.15Å; F43-F186 WeakPolarHBondContact CD2-O 3.33Å; F43-F186 HydrophobicContact CG-CD1 4.5Å; F43-F189 HydrophobicContact CD2-CB 4.35Å; F43-F189 AromaticContact CD2-CD1 3.88Å; F43-F189 HydrophobicContact CD2-CD1 3.88Å; F43-F189 HydrophobicContact CE2-CB 4.38Å; F43-F189 AromaticContact CE2-CD1 3.39Å; F43-F189 HydrophobicContact CE2-CD1 3.39Å; F43-F189 AromaticContact CE2-CE1 3.92Å; F43-F189 HydrophobicContact CE2-CE1 3.92Å; F43-F189 HydrophobicContact CE2-CG 4.12Å; F43-F189 HydrophobicContact CZ-CD1 4.47Å; F43-G190 VanDerWaalsContact CD2-CA 3.42Å; F43-G190 VanDerWaalsContact CE2-CA 3.48Å; F43-L193 HydrophobicContact CE2-CD1 3.92Å; F43-L193 HydrophobicContact CZ-CD1 3.72Å; F43-V225 HydrophobicContact CD1-CG1 4.21Å; F43-V225 HydrophobicContact CE1-CG1 3.7Å; F43-C229 VanDerWaalsContact CD1-SG 3.53Å
44	G	95.9	Very high	92.1	Very high	0 Å²	0	22.9 Å²	22.9	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-63.7	-42.3	-177.2	0	0	0	0	0	112.2	M40 A41 C48	M40-G44 PolarHBondContact O-N 3.49Å; A41-G44 PolarHBondContact O-N 3.09Å; G44-C48 PolarHBondContact O-N 3.45Å; G44-C48 PolarHBondContact O-SG 3.21Å
45	R	95.1	Very high	91.6	Very high	13 Å²	13	18.9 Å²	18.9	5%	0.049	10%	0.1	C	C	.	.	H	α-helix	trans	-59.3	-53.5	175.9	179.3	-123.5	-178.9	-162.2	-0.2	111.4	A41 F43 F47 C48 Y49 M113 A156 D157 I159	A41-R45 VanDerWaalsContact O-CB 3.3Å; A41-R45 WeakPolarHBondContact O-CB 3.17Å; A41-R45 PolarHBondContact O-N 3.49Å; F43-R45 PolarHBondContact O-N 3.04Å; R45-F47 PolarHBondContact O-N 2.96Å; R45-C48 PolarHBondContact O-N 3.41Å; R45-Y49 WeakPolarHBondContact O-CB 3.23Å; R45-Y49 PolarHBondContact O-N 3.25Å; R45-M113 HydrophobicContact CB-CE 4.42Å; R45-M113 HydrophobicContact CG-CE 4.15Å; R45-A156 HydrophobicContact CG-CB 4.49Å; R45-A156 PolarHBondContact NE-O 3.05Å; R45-A156 PolarHBondContact NH2-O 2.86Å; R45-D157 IonicContact NH2-OD1 3.64Å; R45-D157 PolarHBondContact NH2-OD1 3.35Å; R45-D157 VanDerWaalsContact NH2-OD1 3.15Å; R45-I159 HydrophobicContact CG-CG2 4.02Å
46	E	94.2	Very high	91.3	Very high	28 Å²	28	18.9 Å²	18.9	13%	0.131	10%	0.1	C	C	.	.	H	α-helix	trans	-69.3	-34.2	-176.3	-157.6	73.7	175.8	0	0	112.6	M42 F43 C48 Y49 A50 T187	M42-E46 WeakPolarHBondContact O-CB 3.44Å; M42-E46 PolarHBondContact O-N 2.94Å; F43-E46 PolarHBondContact O-N 3.39Å; E46-C48 VanDerWaalsContact C-N 3.35Å; E46-C48 PolarHBondContact O-N 3.41Å; E46-Y49 PolarHBondContact O-N 3.45Å; E46-A50 WeakPolarHBondContact O-CB 3.5Å; E46-A50 PolarHBondContact O-N 3.4Å; E46-T187 HydrophobicContact CB-CG2 3.89Å; E46-T187 VanDerWaalsContact CD-CG2 3.49Å; E46-T187 HydrophobicContact CG-CG2 3.59Å; E46-T187 WeakPolarHBondContact CG-O 3.34Å
47	F	94.6	Very high	90.5	Very high	13 Å²	13	18.4 Å²	18.4	6%	0.057	10%	0.1	C	C	.	.	H	α-helix	trans	-55.9	-51.1	172.6	179.4	-84.8	0	0	0	111.1	F43 R45 A50 V51 G190 L193 L197 V225	F43-F47 VanDerWaalsContact O-CB 3.25Å; F43-F47 WeakPolarHBondContact O-CB 3.31Å; F43-F47 PolarHBondContact O-N 2.8Å; R45-F47 PolarHBondContact O-N 2.96Å; F47-A50 PolarHBondContact O-N 3.03Å; F47-V51 HydrophobicContact CD1-CG2 4.31Å; F47-V51 HydrophobicContact CE1-CG2 3.99Å; F47-V51 HydrophobicContact CZ-CG2 4.42Å; F47-V51 WeakPolarHBondContact O-CG2 3.49Å; F47-V51 PolarHBondContact O-N 2.85Å; F47-G190 WeakPolarHBondContact CA-O 3.27Å; F47-L193 HydrophobicContact CD2-CB 3.92Å; F47-L193 HydrophobicContact CE2-CB 3.94Å; F47-L197 HydrophobicContact CE1-CD2 4.16Å; F47-L197 HydrophobicContact CZ-CB 4.33Å; F47-L197 HydrophobicContact CZ-CD2 3.83Å; F47-L197 HydrophobicContact CZ-CG 4.46Å; F47-V225 HydrophobicContact CB-CG1 4.42Å; F47-V225 HydrophobicContact CD1-CB 4.26Å; F47-V225 HydrophobicContact CD1-CG1 4.02Å; F47-V225 HydrophobicContact CD2-CG1 4.47Å; F47-V225 HydrophobicContact CE1-CB 4.26Å; F47-V225 HydrophobicContact CE1-CG1 4.42Å; F47-V225 HydrophobicContact CE1-CG2 4.28Å; F47-V225 HydrophobicContact CG-CG1 4.04Å; F47-V225 HydrophobicContact CZ-CG2 4.26Å
48	C	94.9	Very high	89.8	Confident	0 Å²	0	18.1 Å²	18.1	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-66.9	-39.5	179.9	-65.2	0	0	0	0	112.2	G44 R45 E46 A50 V51 E52 M113 M117 F152	G44-C48 PolarHBondContact O-N 3.45Å; G44-C48 PolarHBondContact O-SG 3.21Å; R45-C48 PolarHBondContact O-N 3.41Å; E46-C48 VanDerWaalsContact C-N 3.35Å; E46-C48 PolarHBondContact O-N 3.41Å; C48-A50 VanDerWaalsContact C-N 3.33Å; C48-A50 PolarHBondContact O-N 3.29Å; C48-V51 PolarHBondContact O-N 3.49Å; C48-E52 PolarHBondContact O-N 3.25Å; C48-M113 HydrophobicContact CB-CE 4.42Å; C48-M117 HydrophobicContact CB-CE 3.52Å; C48-M117 VanDerWaalsContact SG-CE 3.51Å; C48-F152 HydrophobicContact CB-CE2 3.85Å; C48-F152 HydrophobicContact CB-CZ 3.52Å
49	Y	91.8	Very high	89.3	Confident	48 Å²	48	18.3 Å²	18.3	19%	0.188	10%	0.104	C	C	.	.	H	α-helix	trans	-63.5	-38.7	176.9	-157	-104.5	0	0	0	111.8	R45 E46 E52 A53 F152 A156	R45-Y49 WeakPolarHBondContact O-CB 3.23Å; R45-Y49 PolarHBondContact O-N 3.25Å; E46-Y49 PolarHBondContact O-N 3.45Å; Y49-E52 PolarHBondContact O-N 3.4Å; Y49-A53 WeakPolarHBondContact O-CB 3.43Å; Y49-A53 PolarHBondContact O-N 3.46Å; Y49-F152 HydrophobicContact CD2-CE1 4.1Å; Y49-A156 HydrophobicContact CD2-CB 3.91Å; Y49-A156 HydrophobicContact CE2-CB 4.34Å
50	A	89.9	Confident	88.8	Confident	0 Å²	0	18.5 Å²	18.5	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-68.8	-37	174.5	0	0	0	0	0	112.9	E46 F47 C48 A53 A54 G191 Y195	E46-A50 WeakPolarHBondContact O-CB 3.5Å; E46-A50 PolarHBondContact O-N 3.4Å; F47-A50 PolarHBondContact O-N 3.03Å; C48-A50 VanDerWaalsContact C-N 3.33Å; C48-A50 PolarHBondContact O-N 3.29Å; A50-A53 PolarHBondContact O-N 2.86Å; A50-A54 PolarHBondContact O-N 2.72Å; A50-A54 VanDerWaalsContact O-N 3.14Å; A50-G191 WeakPolarHBondContact CB-O 3.49Å; A50-Y195 HydrophobicContact CB-CD1 3.95Å; A50-Y195 HydrophobicContact CB-CD2 4.02Å; A50-Y195 HydrophobicContact CB-CE1 3.91Å; A50-Y195 HydrophobicContact CB-CE2 3.96Å; A50-Y195 HydrophobicContact CB-CG 4Å
51	V	89.1	Confident	88	Confident	0 Å²	0	21.1 Å²	21.1	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-65.1	-43.7	172.9	171.7	0	0	0	0	111	F47 C48 A54 Y55 L197 M218	F47-V51 HydrophobicContact CD1-CG2 4.31Å; F47-V51 HydrophobicContact CE1-CG2 3.99Å; F47-V51 HydrophobicContact CZ-CG2 4.42Å; F47-V51 WeakPolarHBondContact O-CG2 3.49Å; F47-V51 PolarHBondContact O-N 2.85Å; C48-V51 PolarHBondContact O-N 3.49Å; V51-A54 PolarHBondContact O-N 3.08Å; V51-Y55 HydrophobicContact CG1-CD2 4.34Å; V51-Y55 PolarHBondContact O-N 3.01Å; V51-Y55 VanDerWaalsContact O-N 3.15Å; V51-L197 HydrophobicContact CG2-CB 4.3Å; V51-L197 HydrophobicContact CG2-CD2 3.76Å; V51-M218 HydrophobicContact CG1-CB 4.3Å; V51-M218 HydrophobicContact CG1-SD 4.44Å
52	E	89.4	Confident	87.3	Confident	5 Å²	5	24.8 Å²	24.8	2%	0.023	15%	0.145	C	C	.	.	H	α-helix	trans	-60	-50.6	173.6	178.3	-176.2	-139.3	0	0	111.1	C48 Y49 A54 Y55 V56 F152	C48-E52 PolarHBondContact O-N 3.25Å; Y49-E52 PolarHBondContact O-N 3.4Å; E52-A54 PolarHBondContact O-N 3.03Å; E52-A54 VanDerWaalsContact O-N 3.1Å; E52-Y55 PolarHBondContact O-N 3.34Å; E52-V56 HydrophobicContact CG-CB 3.87Å; E52-V56 HydrophobicContact CG-CG1 4.39Å; E52-V56 HydrophobicContact CG-CG2 4.33Å; E52-V56 VanDerWaalsContact O-CB 3.23Å; E52-V56 WeakPolarHBondContact O-CB 3.3Å; E52-V56 VanDerWaalsContact O-CG1 3.25Å; E52-V56 WeakPolarHBondContact O-CG1 3.34Å; E52-V56 PolarHBondContact O-N 2.78Å; E52-F152 HydrophobicContact CB-CD1 4.47Å; E52-F152 HydrophobicContact CB-CE1 4.08Å; E52-F152 HydrophobicContact CG-CD1 4.41Å; E52-F152 HydrophobicContact CG-CE1 4.47Å; E52-F152 WeakPolarHBondContact OE1-CD1 3.34Å; E52-F152 WeakPolarHBondContact OE2-CD1 3.4Å; E52-F152 WeakPolarHBondContact OE2-CE1 3.37Å
53	A	84.3	Confident	86.8	Confident	40 Å²	40	25.3 Å²	25.3	33%	0.331	15%	0.148	S	C	.	.	H	α-helix	trans	-55.2	-32.8	179.3	0	0	0	0	0	112.7	Y49 A50 Y195	Y49-A53 WeakPolarHBondContact O-CB 3.43Å; Y49-A53 PolarHBondContact O-N 3.46Å; A50-A53 PolarHBondContact O-N 2.86Å; A53-Y195 HydrophobicContact CB-CE1 4.18Å
54	A	79.2	Confident	86	Confident	35 Å²	35	26.1 Å²	26.1	29%	0.289	16%	0.163	S	C	.	.	H	α-helix	trans	-74.9	-35.3	175.8	0	0	0	0	0	113.7	A50 V51 E52	A50-A54 PolarHBondContact O-N 2.72Å; A50-A54 VanDerWaalsContact O-N 3.14Å; V51-A54 PolarHBondContact O-N 3.08Å; E52-A54 PolarHBondContact O-N 3.03Å; E52-A54 VanDerWaalsContact O-N 3.1Å
55	Y	79.9	Confident	85.1	Confident	27 Å²	27	26.5 Å²	26.5	11%	0.106	17%	0.165	C	C	.	.	H	α-helix	trans	-118.8	-12.8	-166.3	-76.1	-72.5	0	0	0	116.5	V51 E52 T57 P58 V59 G198 F215 M218	V51-Y55 HydrophobicContact CG1-CD2 4.34Å; V51-Y55 PolarHBondContact O-N 3.01Å; V51-Y55 VanDerWaalsContact O-N 3.15Å; E52-Y55 PolarHBondContact O-N 3.34Å; Y55-T57 VanDerWaalsContact C-N 3.26Å; Y55-T57 PolarHBondContact O-N 2.9Å; Y55-P58 VanDerWaalsContact O-CD 3.29Å; Y55-P58 WeakPolarHBondContact O-CD 3.5Å; Y55-V59 WeakPolarHBondContact O-CB 3.17Å; Y55-V59 WeakPolarHBondContact O-CG2 3.34Å; Y55-V59 PolarHBondContact O-N 3.26Å; Y55-G198 PolarHBondContact OH-O 3.48Å; Y55-F215 HydrophobicContact CD1-CE1 4.28Å; Y55-M218 HydrophobicContact CD2-CE 4.2Å; Y55-M218 HydrophobicContact CD2-CG 4.31Å; Y55-M218 HydrophobicContact CD2-SD 4.34Å; Y55-M218 HydrophobicContact CE1-CE 4.31Å; Y55-M218 HydrophobicContact CE2-CE 3.22Å; Y55-M218 HydrophobicContact CE2-CG 4.15Å; Y55-M218 HydrophobicContact CE2-SD 3.78Å; Y55-M218 WeakPolarHBondContact OH-CE 3.3Å
56	V	83.9	Confident	84.3	Confident	1 Å²	1	29.1 Å²	29.1	1%	0.006	18%	0.183	C	C	.	.	H	α-helix	trans	-57.6	-42.3	-176.9	64.7	0	0	0	0	111.5	E52 V59 L60 W74 V149	E52-V56 HydrophobicContact CG-CB 3.87Å; E52-V56 HydrophobicContact CG-CG1 4.39Å; E52-V56 HydrophobicContact CG-CG2 4.33Å; E52-V56 VanDerWaalsContact O-CB 3.23Å; E52-V56 WeakPolarHBondContact O-CB 3.3Å; E52-V56 VanDerWaalsContact O-CG1 3.25Å; E52-V56 WeakPolarHBondContact O-CG1 3.34Å; E52-V56 PolarHBondContact O-N 2.78Å; V56-V59 PolarHBondContact O-N 3.44Å; V56-L60 HydrophobicContact CG2-CD1 3.9Å; V56-L60 HydrophobicContact CG2-CG 4.36Å; V56-L60 WeakPolarHBondContact O-CB 3.22Å; V56-L60 VanDerWaalsContact O-CG 3.26Å; V56-L60 WeakPolarHBondContact O-CG 3.49Å; V56-L60 PolarHBondContact O-N 3Å; V56-W74 HydrophobicContact CG1-CH2 4.47Å; V56-W74 HydrophobicContact CG1-CZ2 3.62Å; V56-V149 HydrophobicContact CG2-CB 4.43Å; V56-V149 HydrophobicContact CG2-CG1 3.78Å; V56-V149 HydrophobicContact CG2-CG2 3.68Å
57	T	77.9	Confident	83	Confident	48 Å²	48	32.1 Å²	32.1	29%	0.294	21%	0.207	S	C	.	.	H	α-helix	trans	-65.8	-54	178.6	-55	0	0	0	0	111.7	Y55 V59 L60 L61 Y70	Y55-T57 VanDerWaalsContact C-N 3.26Å; Y55-T57 PolarHBondContact O-N 2.9Å; T57-V59 VanDerWaalsContact C-N 3.3Å; T57-V59 PolarHBondContact O-N 2.74Å; T57-L60 PolarHBondContact O-N 2.87Å; T57-L61 HydrophobicContact CG2-CD1 3.99Å; T57-L61 HydrophobicContact CG2-CG 4.45Å; T57-L61 WeakPolarHBondContact O-CB 3.48Å; T57-L61 WeakPolarHBondContact O-CG 3.18Å; T57-L61 PolarHBondContact O-N 3.01Å; T57-Y70 HydrophobicContact CG2-CE2 4.3Å; T57-Y70 WeakPolarHBondContact OG1-CE2 3.27Å
58	P	77.6	Confident	81.8	Confident	60 Å²	60	35.9 Å²	35.9	39%	0.39	24%	0.236	S	C	.	.	H	α-helix	trans	-51.2	-44.8	171.7	-29.2	32.2	0	0	0	114.2	Y55 L61 S62	Y55-P58 VanDerWaalsContact O-CD 3.29Å; Y55-P58 WeakPolarHBondContact O-CD 3.5Å; P58-L61 PolarHBondContact O-N 3.33Å; P58-S62 VanDerWaalsContact O-CB 3.32Å; P58-S62 WeakPolarHBondContact O-CB 3.18Å; P58-S62 PolarHBondContact O-N 3.48Å; P58-S62 PolarHBondContact O-OG 2.94Å
59	V	82.8	Confident	81	Confident	3 Å²	3	39 Å²	39	2%	0.018	25%	0.252	C	S	.	.	H	α-helix	trans	-63.2	-49.9	-179.6	170.9	0	0	0	0	110.7	Y55 V56 T57 L61 S62 V63 Y120 L121 T145 F215	Y55-V59 WeakPolarHBondContact O-CB 3.17Å; Y55-V59 WeakPolarHBondContact O-CG2 3.34Å; Y55-V59 PolarHBondContact O-N 3.26Å; V56-V59 PolarHBondContact O-N 3.44Å; T57-V59 VanDerWaalsContact C-N 3.3Å; T57-V59 PolarHBondContact O-N 2.74Å; V59-L61 VanDerWaalsContact C-N 3.33Å; V59-L61 PolarHBondContact O-N 3.42Å; V59-S62 PolarHBondContact O-N 2.74Å; V59-S62 PolarHBondContact O-OG 3.06Å; V59-V63 WeakPolarHBondContact O-CG2 3.34Å; V59-V63 PolarHBondContact O-N 3.24Å; V59-V63 VanDerWaalsContact O-N 3.16Å; V59-Y120 HydrophobicContact CG1-CD2 4.37Å; V59-Y120 VanDerWaalsContact CG1-O 3.28Å; V59-Y120 WeakPolarHBondContact CG1-O 3.34Å; V59-L121 HydrophobicContact CG2-CD2 4.15Å; V59-T145 HydrophobicContact CG1-CG2 3.79Å; V59-F215 HydrophobicContact CB-CZ 4.47Å; V59-F215 HydrophobicContact CG2-CD1 3.67Å; V59-F215 HydrophobicContact CG2-CD2 4.22Å; V59-F215 HydrophobicContact CG2-CE1 3.44Å; V59-F215 VanDerWaalsContact CG2-CE1 3.44Å; V59-F215 HydrophobicContact CG2-CE2 4.01Å; V59-F215 HydrophobicContact CG2-CG 4.08Å; V59-F215 HydrophobicContact CG2-CZ 3.62Å
60	L	83.6	Confident	80	Confident	4 Å²	4	40.5 Å²	40.5	2%	0.021	26%	0.258	C	S	.	.	H	α-helix	trans	-62.5	-39.7	-179.7	-71.3	172.1	0	0	0	112.3	V56 T57 V63 G64 L65 V73 T145 M146 V149	V56-L60 HydrophobicContact CG2-CD1 3.9Å; V56-L60 HydrophobicContact CG2-CG 4.36Å; V56-L60 WeakPolarHBondContact O-CB 3.22Å; V56-L60 VanDerWaalsContact O-CG 3.26Å; V56-L60 WeakPolarHBondContact O-CG 3.49Å; V56-L60 PolarHBondContact O-N 3Å; T57-L60 PolarHBondContact O-N 2.87Å; L60-V63 PolarHBondContact O-N 2.85Å; L60-G64 PolarHBondContact O-N 3.44Å; L60-L65 HydrophobicContact CB-CB 4.3Å; L60-L65 HydrophobicContact CB-CD2 4.11Å; L60-L65 HydrophobicContact CD1-CD2 4.18Å; L60-L65 HydrophobicContact CD2-CD2 4.12Å; L60-L65 HydrophobicContact CG-CD2 4.37Å; L60-L65 VanDerWaalsContact O-CB 3.32Å; L60-L65 WeakPolarHBondContact O-CB 3.32Å; L60-L65 PolarHBondContact O-N 2.83Å; L60-V73 HydrophobicContact CD1-CG1 4.45Å; L60-T145 HydrophobicContact CD2-CG2 3.7Å; L60-M146 HydrophobicContact CD2-CG 4.19Å; L60-V149 HydrophobicContact CD2-CG2 4.37Å
61	L	78.9	Confident	79.2	Confident	94 Å²	94	44.1 Å²	44.1	49%	0.492	28%	0.283	S	S	.	.	H	α-helix	trans	-66.7	-41.6	175.6	-68.8	175.5	0	0	0	111.8	T57 P58 V59 V63 G64	T57-L61 HydrophobicContact CG2-CD1 3.99Å; T57-L61 HydrophobicContact CG2-CG 4.45Å; T57-L61 WeakPolarHBondContact O-CB 3.48Å; T57-L61 WeakPolarHBondContact O-CG 3.18Å; T57-L61 PolarHBondContact O-N 3.01Å; P58-L61 PolarHBondContact O-N 3.33Å; V59-L61 VanDerWaalsContact C-N 3.33Å; V59-L61 PolarHBondContact O-N 3.42Å; L61-V63 PolarHBondContact O-N 3.49Å; L61-G64 WeakPolarHBondContact O-CA 3.3Å; L61-G64 PolarHBondContact O-N 3.36Å
62	S	79.7	Confident	78.7	Confident	78 Å²	78	48.6 Å²	48.6	55%	0.545	31%	0.306	S	S	.	.	H	α-helix	trans	-62.2	-29.5	178.7	77.2	0	0	0	0	113.2	P58 V59 G64	P58-S62 VanDerWaalsContact O-CB 3.32Å; P58-S62 WeakPolarHBondContact O-CB 3.18Å; P58-S62 PolarHBondContact O-N 3.48Å; P58-S62 PolarHBondContact O-OG 2.94Å; V59-S62 PolarHBondContact O-N 2.74Å; V59-S62 PolarHBondContact O-OG 3.06Å; S62-G64 VanDerWaalsContact C-N 3.31Å
63	V	84.3	Confident	78.2	Confident	13 Å²	13	48.5 Å²	48.5	8%	0.079	31%	0.306	C	S	.	.	T	Hydrogen-bonded Turn	trans	-82.4	-12	176.4	-179	0	0	0	0	111.9	V59 L60 L61 A124 L138 A141 I142 T145	V59-V63 WeakPolarHBondContact O-CG2 3.34Å; V59-V63 PolarHBondContact O-N 3.24Å; V59-V63 VanDerWaalsContact O-N 3.16Å; L60-V63 PolarHBondContact O-N 2.85Å; L61-V63 PolarHBondContact O-N 3.49Å; V63-A124 HydrophobicContact CG2-CB 4.27Å; V63-L138 WeakPolarHBondContact O-CD1 3.26Å; V63-A141 HydrophobicContact CG1-CB 3.63Å; V63-I142 HydrophobicContact CG1-CB 4.29Å; V63-I142 HydrophobicContact CG1-CG1 3.73Å; V63-I142 VanDerWaalsContact CG1-N 3.3Å; V63-I142 WeakPolarHBondContact O-CG1 3.5Å; V63-T145 HydrophobicContact CG2-CG2 4.45Å
64	G	79.4	Confident	77.8	Confident	39 Å²	39	49.9 Å²	49.9	40%	0.402	30%	0.303	S	S	.	.	T	Hydrogen-bonded Turn	trans	93.2	23.8	176.1	0	0	0	0	0	114.6	L60 L61 S62 P66	L60-G64 PolarHBondContact O-N 3.44Å; L61-G64 WeakPolarHBondContact O-CA 3.3Å; L61-G64 PolarHBondContact O-N 3.36Å; S62-G64 VanDerWaalsContact C-N 3.31Å; G64-P66 WeakPolarHBondContact O-CD 3.46Å
65	L	77.8	Confident	77.9	Confident	8 Å²	8	51.9 Å²	51.9	4%	0.042	31%	0.305	C	S	.	.			trans	-64.8	124.9	172.9	-174.1	72.1	0	0	0	109.6	L60 S67 L69 V73 I142 M146	L60-L65 HydrophobicContact CB-CB 4.3Å; L60-L65 HydrophobicContact CB-CD2 4.11Å; L60-L65 HydrophobicContact CD1-CD2 4.18Å; L60-L65 HydrophobicContact CD2-CD2 4.12Å; L60-L65 HydrophobicContact CG-CD2 4.37Å; L60-L65 VanDerWaalsContact O-CB 3.32Å; L60-L65 WeakPolarHBondContact O-CB 3.32Å; L60-L65 PolarHBondContact O-N 2.83Å; L65-S67 PolarHBondContact O-N 3.25Å; L65-L69 HydrophobicContact CD1-CB 3.78Å; L65-L69 HydrophobicContact CD1-CD1 3.93Å; L65-L69 HydrophobicContact CD1-CG 4.49Å; L65-L69 HydrophobicContact CD2-CB 4.35Å; L65-L69 HydrophobicContact CG-CB 4.09Å; L65-V73 HydrophobicContact CD2-CG2 4.16Å; L65-I142 HydrophobicContact CB-CG2 4.48Å; L65-I142 HydrophobicContact CD1-CG2 3.52Å; L65-M146 HydrophobicContact CD1-CE 4.28Å; L65-M146 HydrophobicContact CD1-CG 4.28Å; L65-M146 HydrophobicContact CD1-SD 3.54Å; L65-M146 VanDerWaalsContact CD1-SD 3.54Å
66	P	76.4	Confident	78.1	Confident	67 Å²	67	54.1 Å²	54.1	44%	0.435	32%	0.318	S	S	.	.			trans	-58.4	136.2	172.2	-22.7	32.7	0	0	0	111.1	G64 S68 L69	G64-P66 WeakPolarHBondContact O-CD 3.46Å; P66-S68 PolarHBondContact O-N 3.03Å; P66-L69 HydrophobicContact CG-CD1 4.37Å; P66-L69 PolarHBondContact O-N 2.63Å
67	S	67.4	Low	78.1	Confident	91 Å²	91	54.1 Å²	54.1	64%	0.636	32%	0.318	S	S	*	.	H	α-helix	trans	-57.5	-21.6	-177.7	-43.8	0	0	0	0	113.9	L65 L69 Y70	L65-S67 PolarHBondContact O-N 3.25Å; S67-L69 VanDerWaalsContact C-N 3.33Å; S67-L69 PolarHBondContact O-N 3.45Å; S67-Y70 WeakPolarHBondContact O-CB 3.5Å
68	S	70.6	Confident	78.3	Confident	93 Å²	93	52.2 Å²	52.2	65%	0.65	31%	0.307	S	S	*	.	H	α-helix	trans	-70.6	-24.4	175	56.8	0	0	0	0	114.1	P66	P66-S68 PolarHBondContact O-N 3.03Å
69	L	77.2	Confident	78.7	Confident	66 Å²	66	51.8 Å²	51.8	35%	0.346	30%	0.301	S	S	.	.	H	α-helix	trans	-90.3	-14.3	179.5	-62.8	-177.8	0	0	0	112.8	L65 P66 S67 S71 I72 V73	L65-L69 HydrophobicContact CD1-CB 3.78Å; L65-L69 HydrophobicContact CD1-CD1 3.93Å; L65-L69 HydrophobicContact CD1-CG 4.49Å; L65-L69 HydrophobicContact CD2-CB 4.35Å; L65-L69 HydrophobicContact CG-CB 4.09Å; P66-L69 HydrophobicContact CG-CD1 4.37Å; P66-L69 PolarHBondContact O-N 2.63Å; S67-L69 VanDerWaalsContact C-N 3.33Å; S67-L69 PolarHBondContact O-N 3.45Å; L69-S71 VanDerWaalsContact C-N 3.33Å; L69-S71 PolarHBondContact O-N 3.44Å; L69-I72 HydrophobicContact CD2-CD1 3.71Å; L69-I72 WeakPolarHBondContact O-CB 2.87Å; L69-I72 PolarHBondContact O-N 3.26Å; L69-I72 VanDerWaalsContact O-N 3.1Å; L69-V73 PolarHBondContact O-N 2.98Å
70	Y	71.4	Confident	78.9	Confident	78 Å²	78	54 Å²	54	31%	0.306	31%	0.312	S	S	.	.	H	α-helix	trans	-51.9	-51.2	175.8	162.3	-94	0	0	0	111.4	T57 S67 I72 V73 W74	T57-Y70 HydrophobicContact CG2-CE2 4.3Å; T57-Y70 WeakPolarHBondContact OG1-CE2 3.27Å; S67-Y70 WeakPolarHBondContact O-CB 3.5Å; Y70-I72 PolarHBondContact O-N 3.28Å; Y70-I72 VanDerWaalsContact O-N 3.14Å; Y70-V73 WeakPolarHBondContact O-CB 3.28Å; Y70-V73 PolarHBondContact O-N 3.34Å; Y70-W74 AromaticContact CD2-CD1 3.77Å; Y70-W74 AromaticContact CD2-NE1 3.63Å; Y70-W74 AromaticContact CE1-CD1 3.96Å; Y70-W74 AromaticContact CE2-CD1 3.4Å; Y70-W74 VanDerWaalsContact CE2-CD1 3.4Å; Y70-W74 AromaticContact CE2-CE2 3.8Å; Y70-W74 HydrophobicContact CE2-CG 4.47Å; Y70-W74 HydrophobicContact CE2-CZ2 4.4Å; Y70-W74 AromaticContact CE2-NE1 2.91Å; Y70-W74 AromaticContact CZ-CD1 3.48Å; Y70-W74 VanDerWaalsContact CZ-CD1 3.48Å; Y70-W74 AromaticContact CZ-CE2 3.74Å; Y70-W74 AromaticContact CZ-NE1 3.19Å; Y70-W74 PolarHBondContact O-N 2.82Å; Y70-W74 PolarHBondContact OH-NE1 3.23Å
71	S	72.5	Confident	78.7	Confident	76 Å²	76	53.9 Å²	53.9	53%	0.531	31%	0.311	S	S	.	.	H	α-helix	trans	-62.4	-27.1	-177.6	-50.1	0	0	0	0	112.6	L69 F75	L69-S71 VanDerWaalsContact C-N 3.33Å; L69-S71 PolarHBondContact O-N 3.44Å; S71-F75 VanDerWaalsContact O-CB 3.31Å; S71-F75 WeakPolarHBondContact O-CB 3.49Å; S71-F75 PolarHBondContact O-N 3.43Å; S71-F75 VanDerWaalsContact O-N 3.11Å
72	I	79.2	Confident	78.8	Confident	95 Å²	95	51.3 Å²	51.3	49%	0.487	30%	0.297	S	S	.	.	H	α-helix	trans	-70.3	-39.6	176.7	-60.4	178.8	0	0	0	110.7	L69 Y70 F75 L76	L69-I72 HydrophobicContact CD2-CD1 3.71Å; L69-I72 WeakPolarHBondContact O-CB 2.87Å; L69-I72 PolarHBondContact O-N 3.26Å; L69-I72 VanDerWaalsContact O-N 3.1Å; Y70-I72 PolarHBondContact O-N 3.28Å; Y70-I72 VanDerWaalsContact O-N 3.14Å; I72-F75 PolarHBondContact O-N 3.13Å; I72-L76 WeakPolarHBondContact O-CB 3.39Å; I72-L76 PolarHBondContact O-N 2.95Å
73	V	78.9	Confident	78.9	Confident	2 Å²	2	51.2 Å²	51.2	1%	0.012	29%	0.289	C	S	.	.	H	α-helix	trans	-59.9	-49.9	177.6	179.8	0	0	0	0	110	L60 L65 L69 Y70 F75 L76 M146 V149 V150	L60-V73 HydrophobicContact CD1-CG1 4.45Å; L65-V73 HydrophobicContact CD2-CG2 4.16Å; L69-V73 PolarHBondContact O-N 2.98Å; Y70-V73 WeakPolarHBondContact O-CB 3.28Å; Y70-V73 PolarHBondContact O-N 3.34Å; V73-F75 VanDerWaalsContact C-N 3.26Å; V73-F75 PolarHBondContact O-N 3.47Å; V73-L76 PolarHBondContact O-N 3.47Å; V73-M146 HydrophobicContact CG2-CE 3.47Å; V73-M146 VanDerWaalsContact CG2-CE 3.47Å; V73-M146 HydrophobicContact CG2-CG 4.03Å; V73-M146 HydrophobicContact CG2-SD 4.49Å; V73-V149 HydrophobicContact CG1-CB 4.14Å; V73-V149 HydrophobicContact CG1-CG1 3.63Å; V73-V150 HydrophobicContact CG1-CG2 4.23Å
74	W	76.1	Confident	78.7	Confident	70 Å²	70	53.9 Å²	53.9	27%	0.265	30%	0.303	S	S	.	.	H	α-helix	trans	-64.8	-28.2	179.4	-78.2	78.5	0	0	0	113.8	V56 Y70 P78 L336	V56-W74 HydrophobicContact CG1-CH2 4.47Å; V56-W74 HydrophobicContact CG1-CZ2 3.62Å; Y70-W74 AromaticContact CD2-CD1 3.77Å; Y70-W74 AromaticContact CD2-NE1 3.63Å; Y70-W74 AromaticContact CE1-CD1 3.96Å; Y70-W74 AromaticContact CE2-CD1 3.4Å; Y70-W74 VanDerWaalsContact CE2-CD1 3.4Å; Y70-W74 AromaticContact CE2-CE2 3.8Å; Y70-W74 HydrophobicContact CE2-CG 4.47Å; Y70-W74 HydrophobicContact CE2-CZ2 4.4Å; Y70-W74 AromaticContact CE2-NE1 2.91Å; Y70-W74 AromaticContact CZ-CD1 3.48Å; Y70-W74 VanDerWaalsContact CZ-CD1 3.48Å; Y70-W74 AromaticContact CZ-CE2 3.74Å; Y70-W74 AromaticContact CZ-NE1 3.19Å; Y70-W74 PolarHBondContact O-N 2.82Å; Y70-W74 PolarHBondContact OH-NE1 3.23Å; W74-P78 WeakPolarHBondContact O-CD 3.49Å; W74-P78 WeakPolarHBondContact O-CG 3.44Å; W74-L336 HydrophobicContact CE3-CD2 4.25Å; W74-L336 HydrophobicContact CZ3-CD2 3.74Å
75	F	79.6	Confident	78.6	Confident	76 Å²	76	52.4 Å²	52.4	33%	0.333	29%	0.285	S	S	.	.	H	α-helix	trans	-82.9	-28.6	178.6	-163.9	-117.6	0	0	0	112.7	S71 I72 V73 P78 I79 I488	S71-F75 VanDerWaalsContact O-CB 3.31Å; S71-F75 WeakPolarHBondContact O-CB 3.49Å; S71-F75 PolarHBondContact O-N 3.43Å; S71-F75 VanDerWaalsContact O-N 3.11Å; I72-F75 PolarHBondContact O-N 3.13Å; V73-F75 VanDerWaalsContact C-N 3.26Å; V73-F75 PolarHBondContact O-N 3.47Å; F75-P78 WeakPolarHBondContact O-CD 3.2Å; F75-I79 HydrophobicContact CD1-CD1 3.28Å; F75-I79 HydrophobicContact CD1-CG1 4.24Å; F75-I79 HydrophobicContact CE1-CD1 3.24Å; F75-I79 HydrophobicContact CE1-CG1 4.09Å; F75-I79 HydrophobicContact CG-CD1 4.12Å; F75-I79 HydrophobicContact CZ-CD1 4.04Å; F75-I79 HydrophobicContact CZ-CG1 4.43Å; F75-I79 WeakPolarHBondContact O-CD1 3.14Å; F75-I79 WeakPolarHBondContact O-CG1 3.35Å; F75-I79 PolarHBondContact O-N 3.26Å; F75-I488 HydrophobicContact CE2-CB 4.35Å; F75-I488 HydrophobicContact CE2-CG2 3.81Å; F75-I488 HydrophobicContact CZ-CG2 3.91Å
76	L	84.6	Confident	78.2	Confident	74 Å²	74	52.1 Å²	52.1	39%	0.387	28%	0.284	S	S	.	.	H	α-helix	trans	-68.1	-42.2	-174.9	-175.4	58.7	0	0	0	112	I72 V73 I79 L80 V150	I72-L76 WeakPolarHBondContact O-CB 3.39Å; I72-L76 PolarHBondContact O-N 2.95Å; V73-L76 PolarHBondContact O-N 3.47Å; L76-I79 PolarHBondContact O-N 2.83Å; L76-L80 HydrophobicContact CD1-CD1 4.26Å; L76-L80 HydrophobicContact CD1-CG 4.22Å; L76-L80 HydrophobicContact CG-CD1 4Å; L76-L80 HydrophobicContact CG-CG 4.38Å; L76-L80 WeakPolarHBondContact O-CG 3.35Å; L76-L80 PolarHBondContact O-N 3.47Å; L76-V150 HydrophobicContact CB-CG2 4.43Å; L76-V150 HydrophobicContact CD2-CG1 3.95Å; L76-V150 HydrophobicContact CD2-CG2 3.87Å; L76-V150 HydrophobicContact CG-CG1 4.09Å; L76-V150 HydrophobicContact CG-CG2 4.4Å
77	S	83.6	Confident	78.2	Confident	2 Å²	2	51.9 Å²	51.9	1%	0.014	28%	0.281	C	S	.	.	H	α-helix	trans	-59.8	-52.5	179.5	169.7	0	0	0	0	112.1	I79 L80 G81 D153	S77-I79 VanDerWaalsContact C-N 3.27Å; S77-I79 PolarHBondContact O-N 3.09Å; S77-L80 PolarHBondContact O-N 3.11Å; S77-G81 PolarHBondContact O-N 2.76Å; S77-D153 VanDerWaalsContact CB-CB 3.45Å; S77-D153 WeakPolarHBondContact OG-CB 3.4Å
78	P	83.8	Confident	78.5	Confident	8 Å²	8	49.1 Å²	49.1	5%	0.052	26%	0.26	C	S	.	.	H	α-helix	trans	-58.5	-35	178.3	-29.6	36.8	0	0	0	115	W74 F75 G81 F82 Q484 Q487 I488	W74-P78 WeakPolarHBondContact O-CD 3.49Å; W74-P78 WeakPolarHBondContact O-CG 3.44Å; F75-P78 WeakPolarHBondContact O-CD 3.2Å; P78-G81 WeakPolarHBondContact O-CA 3.46Å; P78-F82 WeakPolarHBondContact O-CB 3.39Å; P78-F82 PolarHBondContact O-N 2.89Å; P78-Q484 VanDerWaalsContact CA-OE1 3.27Å; P78-Q484 PolarHBondContact O-OE1 2.91Å; P78-Q487 HydrophobicContact CB-CB 3.77Å; P78-Q487 HydrophobicContact CG-CB 3.68Å; P78-Q487 HydrophobicContact CG-CG 4.47Å; P78-I488 HydrophobicContact CB-CD1 4.48Å; P78-I488 HydrophobicContact CB-CG1 3.65Å
79	I	85.4	Confident	78.3	Confident	50 Å²	50	45.4 Å²	45.4	26%	0.256	24%	0.237	S	C	.	.	H	α-helix	trans	-65.5	-48.2	174.7	-67.5	166	0	0	0	110.6	F75 L76 S77 G81 F82 L83 I488	F75-I79 HydrophobicContact CD1-CD1 3.28Å; F75-I79 HydrophobicContact CD1-CG1 4.24Å; F75-I79 HydrophobicContact CE1-CD1 3.24Å; F75-I79 HydrophobicContact CE1-CG1 4.09Å; F75-I79 HydrophobicContact CG-CD1 4.12Å; F75-I79 HydrophobicContact CZ-CD1 4.04Å; F75-I79 HydrophobicContact CZ-CG1 4.43Å; F75-I79 WeakPolarHBondContact O-CD1 3.14Å; F75-I79 WeakPolarHBondContact O-CG1 3.35Å; F75-I79 PolarHBondContact O-N 3.26Å; L76-I79 PolarHBondContact O-N 2.83Å; S77-I79 VanDerWaalsContact C-N 3.27Å; S77-I79 PolarHBondContact O-N 3.09Å; I79-G81 VanDerWaalsContact C-N 3.31Å; I79-F82 PolarHBondContact O-N 3.26Å; I79-L83 HydrophobicContact CG2-CD1 3.71Å; I79-L83 HydrophobicContact CG2-CG 4.26Å; I79-L83 WeakPolarHBondContact O-CB 3.3Å; I79-L83 VanDerWaalsContact O-CG 3.26Å; I79-L83 WeakPolarHBondContact O-CG 3.47Å; I79-L83 PolarHBondContact O-N 2.84Å; I79-I488 HydrophobicContact CG1-CD1 4.26Å; I79-I488 HydrophobicContact CG1-CG1 4.34Å
80	L	85.9	Confident	77.9	Confident	51 Å²	51	42.9 Å²	42.9	27%	0.267	23%	0.225	S	C	.	.	H	α-helix	trans	-62.3	-42.9	177.6	-67.6	175.7	0	0	0	110.7	L76 S77 L83 L84 V150 F154	L76-L80 HydrophobicContact CD1-CD1 4.26Å; L76-L80 HydrophobicContact CD1-CG 4.22Å; L76-L80 HydrophobicContact CG-CD1 4Å; L76-L80 HydrophobicContact CG-CG 4.38Å; L76-L80 WeakPolarHBondContact O-CG 3.35Å; L76-L80 PolarHBondContact O-N 3.47Å; S77-L80 PolarHBondContact O-N 3.11Å; L80-L83 PolarHBondContact O-N 2.93Å; L80-L84 HydrophobicContact CD2-CD1 4.35Å; L80-L84 VanDerWaalsContact O-CB 3.3Å; L80-L84 WeakPolarHBondContact O-CB 3.29Å; L80-L84 PolarHBondContact O-N 2.68Å; L80-V150 HydrophobicContact CD1-CG1 3.61Å; L80-F154 HydrophobicContact CB-CD2 3.93Å; L80-F154 HydrophobicContact CB-CE2 4.37Å
81	G	80.5	Confident	78	Confident	0 Å²	0	41 Å²	41	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-27.6	-80.9	155.3	0	0	0	0	0	113.7	S77 P78 I79 L83 L84 Q85 F158	S77-G81 PolarHBondContact O-N 2.76Å; P78-G81 WeakPolarHBondContact O-CA 3.46Å; I79-G81 VanDerWaalsContact C-N 3.31Å; G81-L83 VanDerWaalsContact C-N 3.26Å; G81-L83 PolarHBondContact O-N 2.85Å; G81-L84 PolarHBondContact O-N 2.81Å; G81-Q85 WeakPolarHBondContact O-CB 3.28Å; G81-Q85 PolarHBondContact O-N 2.65Å; G81-F158 VanDerWaalsContact CA-CE2 3.41Å; G81-F158 WeakPolarHBondContact O-CZ 3.43Å
82	F	81	Confident	78	Confident	41 Å²	41	37.5 Å²	37.5	18%	0.18	20%	0.201	C	C	.	.	H	α-helix	trans	-56.8	-37.5	-174.4	-175.5	-100.4	0	0	0	113.4	P78 I79 L303 Q484 L485 I488	P78-F82 WeakPolarHBondContact O-CB 3.39Å; P78-F82 PolarHBondContact O-N 2.89Å; I79-F82 PolarHBondContact O-N 3.26Å; F82-L303 HydrophobicContact CE1-CD1 4.18Å; F82-Q484 HydrophobicContact CB-CB 4.17Å; F82-L485 HydrophobicContact CD2-CB 4.22Å; F82-L485 HydrophobicContact CE2-CB 4.21Å; F82-L485 HydrophobicContact CE2-CD1 4.3Å; F82-I488 HydrophobicContact CB-CD1 3.87Å; F82-I488 HydrophobicContact CG-CD1 4.27Å
83	L	80.6	Confident	77.4	Confident	75 Å²	75	34.5 Å²	34.5	39%	0.393	19%	0.186	S	C	.	.	H	α-helix	trans	-78.7	-42.2	-176.7	-68	178.1	0	0	0	113.7	I79 L80 G81 L303	I79-L83 HydrophobicContact CG2-CD1 3.71Å; I79-L83 HydrophobicContact CG2-CG 4.26Å; I79-L83 WeakPolarHBondContact O-CB 3.3Å; I79-L83 VanDerWaalsContact O-CG 3.26Å; I79-L83 WeakPolarHBondContact O-CG 3.47Å; I79-L83 PolarHBondContact O-N 2.84Å; L80-L83 PolarHBondContact O-N 2.93Å; G81-L83 VanDerWaalsContact C-N 3.26Å; G81-L83 PolarHBondContact O-N 2.85Å; L83-L303 HydrophobicContact CD2-CD1 4.26Å; L83-L303 HydrophobicContact CD2-CD2 4.22Å
84	L	81.7	Confident	76.8	Confident	69 Å²	69	40.2 Å²	40.2	36%	0.361	21%	0.212	S	C	.	.	H	α-helix	trans	-97.2	-21.4	-170.5	-60.4	173.5	0	0	0	112.8	L80 G81 P86 V87 V88 F154 F158	L80-L84 HydrophobicContact CD2-CD1 4.35Å; L80-L84 VanDerWaalsContact O-CB 3.3Å; L80-L84 WeakPolarHBondContact O-CB 3.29Å; L80-L84 PolarHBondContact O-N 2.68Å; G81-L84 PolarHBondContact O-N 2.81Å; L84-P86 VanDerWaalsContact C-N 3.33Å; L84-V87 WeakPolarHBondContact O-CA 3.36Å; L84-V87 WeakPolarHBondContact O-CB 3.43Å; L84-V87 PolarHBondContact O-N 2.69Å; L84-V88 PolarHBondContact O-N 2.66Å; L84-F154 HydrophobicContact CB-CE2 3.93Å; L84-F154 HydrophobicContact CB-CZ 4.27Å; L84-F154 HydrophobicContact CD1-CE2 3.56Å; L84-F154 HydrophobicContact CD1-CZ 3.92Å; L84-F154 HydrophobicContact CG-CE2 4.34Å; L84-F158 HydrophobicContact CB-CE1 3.79Å; L84-F158 HydrophobicContact CB-CZ 3.62Å
85	Q	76.2	Confident	76.4	Confident	8 Å²	8	38 Å²	38	4%	0.037	21%	0.207	C	C	.	.	H	α-helix	trans	-54.2	-40	-177.3	-177.1	159.3	37.1	0	0	114.3	G81 G89 F158	G81-Q85 WeakPolarHBondContact O-CB 3.28Å; G81-Q85 PolarHBondContact O-N 2.65Å; Q85-G89 PolarHBondContact O-N 3Å; Q85-F158 HydrophobicContact CB-CE1 3.94Å; Q85-F158 HydrophobicContact CB-CE2 4.44Å; Q85-F158 HydrophobicContact CB-CZ 3.8Å
86	P	70.7	Confident	75.7	Confident	2 Å²	2	44.6 Å²	44.6	1%	0.013	23%	0.23	C	C	.	.	H	α-helix	trans	-70.3	-35.8	176.5	-17.6	32.7	0	0	0	112.7	L84 S90 L306	L84-P86 VanDerWaalsContact C-N 3.33Å; P86-S90 WeakPolarHBondContact O-CB 3.48Å; P86-S90 PolarHBondContact O-N 2.82Å; P86-L306 HydrophobicContact CB-CD1 4.02Å; P86-L306 HydrophobicContact CB-CD2 3.89Å; P86-L306 HydrophobicContact CB-CG 3.55Å; P86-L306 HydrophobicContact CG-CB 4.49Å; P86-L306 HydrophobicContact CG-CD1 3.04Å; P86-L306 HydrophobicContact CG-CD2 3.71Å; P86-L306 HydrophobicContact CG-CG 3.17Å
87	V	75.3	Confident	75.1	Confident	63 Å²	63	43 Å²	43	38%	0.382	23%	0.225	S	C	.	.	H	α-helix	trans	-67.1	-49.6	179.8	-177.7	0	0	0	0	109	L84 S90 A91 M301	L84-V87 WeakPolarHBondContact O-CA 3.36Å; L84-V87 WeakPolarHBondContact O-CB 3.43Å; L84-V87 PolarHBondContact O-N 2.69Å; V87-S90 PolarHBondContact O-N 2.71Å; V87-A91 VanDerWaalsContact O-CB 3.28Å; V87-A91 WeakPolarHBondContact O-CB 3.16Å; V87-A91 PolarHBondContact O-N 3.31Å; V87-M301 WeakPolarHBondContact CG2-O 3.27Å
88	V	73.7	Confident	74.2	Confident	32 Å²	32	54.1 Å²	54.1	19%	0.194	27%	0.267	C	S	.	.	H	α-helix	trans	-68.6	-40.4	179.2	179	0	0	0	0	111.2	L84 A91 S92 Y105 F158	L84-V88 PolarHBondContact O-N 2.66Å; V88-A91 PolarHBondContact O-N 2.79Å; V88-S92 WeakPolarHBondContact O-CB 3.36Å; V88-S92 PolarHBondContact O-N 3.41Å; V88-Y105 HydrophobicContact CG1-CD1 4.19Å; V88-Y105 HydrophobicContact CG1-CE1 4.38Å; V88-F158 HydrophobicContact CB-CD1 3.81Å; V88-F158 HydrophobicContact CB-CE1 3.91Å; V88-F158 HydrophobicContact CG1-CD1 4.03Å; V88-F158 HydrophobicContact CG2-CD1 3.86Å; V88-F158 HydrophobicContact CG2-CE1 3.68Å
89	G	67	Low	73.5	Confident	16 Å²	16	62 Å²	62	17%	0.165	30%	0.296	C	S	.	.	H	α-helix	trans	-57.7	-50.2	174.1	0	0	0	0	0	111.8	Q85 S92 D93	Q85-G89 PolarHBondContact O-N 3Å; G89-S92 PolarHBondContact O-N 3.1Å; G89-S92 PolarHBondContact O-OG 3.39Å; G89-D93 PolarHBondContact O-N 2.89Å; G89-D93 VanDerWaalsContact O-N 3.09Å
90	S	68	Low	72.9	Confident	13 Å²	13	59.7 Å²	59.7	9%	0.091	28%	0.284	C	S	.	.	H	α-helix	trans	-61.7	-43.9	174.4	-175.5	0	0	0	0	112	P86 V87 S92 D93 H94	P86-S90 WeakPolarHBondContact O-CB 3.48Å; P86-S90 PolarHBondContact O-N 2.82Å; V87-S90 PolarHBondContact O-N 2.71Å; S90-S92 VanDerWaalsContact C-N 3.26Å; S90-S92 PolarHBondContact O-N 3.22Å; S90-D93 WeakPolarHBondContact O-CB 3.28Å; S90-D93 PolarHBondContact O-N 3.39Å; S90-D93 VanDerWaalsContact O-N 3.11Å; S90-H94 PolarHBondContact O-N 3Å; S90-H94 PolarHBondContact O-ND1 3Å
91	A	73.3	Confident	72.5	Confident	38 Å²	38	59.4 Å²	59.4	31%	0.314	28%	0.28	S	S	.	.	H	α-helix	trans	-61.5	-37.9	177.6	0	0	0	0	0	111.6	V87 V88 D93 H94 C95 Y105	V87-A91 VanDerWaalsContact O-CB 3.28Å; V87-A91 WeakPolarHBondContact O-CB 3.16Å; V87-A91 PolarHBondContact O-N 3.31Å; V88-A91 PolarHBondContact O-N 2.79Å; A91-D93 VanDerWaalsContact C-N 3.33Å; A91-D93 PolarHBondContact O-N 3.03Å; A91-H94 PolarHBondContact O-N 3.21Å; A91-C95 PolarHBondContact O-N 3.08Å; A91-Y105 VanDerWaalsContact C-CZ 3.47Å; A91-Y105 HydrophobicContact CB-CE1 4.03Å; A91-Y105 VanDerWaalsContact CB-OH 3.27Å; A91-Y105 WeakPolarHBondContact CB-OH 3.4Å; A91-Y105 PolarHBondContact O-OH 2.94Å
92	S	73.8	Confident	72.6	Confident	2 Å²	2	59.7 Å²	59.7	1%	0.014	28%	0.28	C	S	.	.	H	α-helix	trans	-64.5	-36.4	175.1	83.3	0	0	0	0	112	V88 G89 S90 H94 C95 R101 R102	V88-S92 WeakPolarHBondContact O-CB 3.36Å; V88-S92 PolarHBondContact O-N 3.41Å; G89-S92 PolarHBondContact O-N 3.1Å; G89-S92 PolarHBondContact O-OG 3.39Å; S90-S92 VanDerWaalsContact C-N 3.26Å; S90-S92 PolarHBondContact O-N 3.22Å; S92-H94 PolarHBondContact O-N 3.17Å; S92-C95 PolarHBondContact O-N 2.66Å; S92-R101 WeakPolarHBondContact O-CD 3.13Å; S92-R101 WeakPolarHBondContact O-CG 3.42Å; S92-R102 PolarHBondContact OG-NH1 3.21Å
93	D	65.7	Low	72.9	Confident	32 Å²	32	59.5 Å²	59.5	17%	0.171	28%	0.279	C	S	.	.	H	α-helix	trans	-64.9	-20.2	177	-74.6	-29.9	0	0	0	114.1	G89 S90 A91 R101 R102	G89-D93 PolarHBondContact O-N 2.89Å; G89-D93 VanDerWaalsContact O-N 3.09Å; S90-D93 WeakPolarHBondContact O-CB 3.28Å; S90-D93 PolarHBondContact O-N 3.39Å; S90-D93 VanDerWaalsContact O-N 3.11Å; A91-D93 VanDerWaalsContact C-N 3.33Å; A91-D93 PolarHBondContact O-N 3.03Å; D93-R101 WeakPolarHBondContact O-CD 3.44Å; D93-R101 PolarHBondContact O-NH1 3.41Å; D93-R102 IonicContact OD1-CZ 3.1Å; D93-R102 IonicContact OD1-NH1 2.76Å; D93-R102 PolarHBondContact OD1-NH1 3.11Å; D93-R102 IonicContact OD1-NH2 3.34Å; D93-R102 PolarHBondContact OD1-NH2 3.43Å
94	H	65.7	Low	73.2	Confident	123 Å²	123	57 Å²	57	57%	0.569	27%	0.267	S	S	*	.	T	Hydrogen-bonded Turn	trans	-111.4	5.6	-173	-62.8	82.9	0	0	0	113.3	S90 A91 S92 R96	S90-H94 PolarHBondContact O-N 3Å; S90-H94 PolarHBondContact O-ND1 3Å; A91-H94 PolarHBondContact O-N 3.21Å; S92-H94 PolarHBondContact O-N 3.17Å; H94-R96 PolarHBondContact O-N 2.93Å
95	C	68.7	Low	73.4	Confident	24 Å²	24	56.7 Å²	56.7	16%	0.162	26%	0.261	C	S	.	.			trans	-67.4	120.1	-178.8	-165	0	0	0	0	112.1	A91 S92 R101 Y105 L242	A91-C95 PolarHBondContact O-N 3.08Å; S92-C95 PolarHBondContact O-N 2.66Å; C95-R101 HydrophobicContact CB-CG 4.21Å; C95-R101 WeakPolarHBondContact CB-O 3.47Å; C95-Y105 HydrophobicContact CB-CD2 4.08Å; C95-Y105 HydrophobicContact CB-CE2 3.54Å; C95-L242 WeakPolarHBondContact O-CD1 3.47Å
96	R	64.2	Low	74	Confident	213 Å²	213	56.3 Å²	56.3	80%	0.804	26%	0.26	S	S	*	.			trans	-95.9	24	179.1	-64.1	-174.4	176.7	-168.1	-2.8	113.9	H94	H94-R96 PolarHBondContact O-N 2.93Å
97	S	72.7	Confident	75.1	Confident	42 Å²	42	59.2 Å²	59.2	29%	0.294	28%	0.275	S	S	.	.			trans	-63.6	148.3	-178.8	-175.1	0	0	0	0	111.9	W99 G100	S97-W99 PolarHBondContact O-N 3.35Å; S97-W99 PolarHBondContact OG-N 2.79Å; S97-G100 WeakPolarHBondContact CB-O 3.41Å; S97-G100 PolarHBondContact O-N 3.16Å
98	R	64.9	Low	75.9	Confident	234 Å²	234	60.3 Å²	60.3	88%	0.883	28%	0.282	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.9	-21.1	175.2	-68.5	-175.2	175.4	-173.3	-1.1	112.8	G100	R98-G100 PolarHBondContact O-N 3.5Å
99	W	69.1	Low	76.8	Confident	174 Å²	174	59.1 Å²	59.1	66%	0.659	27%	0.274	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.3	6.1	179.2	-73.4	5	0	0	0	113.7	S97 R103 L107	S97-W99 PolarHBondContact O-N 3.35Å; S97-W99 PolarHBondContact OG-N 2.79Å; W99-R103 WeakPolarHBondContact O-CD 3.45Å; W99-L107 HydrophobicContact CZ3-CD2 3.99Å
100	G	71.6	Confident	78.1	Confident	1 Å²	1	58.5 Å²	58.5	1%	0.01	27%	0.268	C	S	.	.			trans	99.8	174.2	-170	0	0	0	0	0	111.6	S97 R98 P104 E239	S97-G100 WeakPolarHBondContact CB-O 3.41Å; S97-G100 PolarHBondContact O-N 3.16Å; R98-G100 PolarHBondContact O-N 3.5Å; G100-P104 WeakPolarHBondContact O-CD 3.07Å; G100-E239 WeakPolarHBondContact CA-OE2 3.37Å
101	R	78.5	Confident	79.5	Confident	46 Å²	46	61.4 Å²	61.4	17%	0.174	29%	0.285	C	S	.	.	S	Bend	trans	-84.9	-42.1	-172.2	172	178.7	72.6	168.6	-1.4	111.5	S92 D93 C95 D169 E239 L242	S92-R101 WeakPolarHBondContact O-CD 3.13Å; S92-R101 WeakPolarHBondContact O-CG 3.42Å; D93-R101 WeakPolarHBondContact O-CD 3.44Å; D93-R101 PolarHBondContact O-NH1 3.41Å; C95-R101 HydrophobicContact CB-CG 4.21Å; C95-R101 WeakPolarHBondContact CB-O 3.47Å; R101-D169 IonicContact CZ-OD2 3.49Å; R101-D169 IonicContact NE-OD2 3.73Å; R101-D169 VanDerWaalsContact NH2-CG 3.3Å; R101-D169 IonicContact NH2-OD1 2.76Å; R101-D169 PolarHBondContact NH2-OD1 2.85Å; R101-D169 IonicContact NH2-OD2 3.78Å; R101-D169 PolarHBondContact NH2-OD2 3.22Å; R101-E239 WeakPolarHBondContact CA-OE1 3.48Å; R101-E239 VanDerWaalsContact CB-OE1 3.3Å; R101-E239 WeakPolarHBondContact CB-OE1 3.35Å; R101-E239 PolarHBondContact N-OE1 3.08Å; R101-E239 PolarHBondContact N-OE2 2.91Å; R101-E239 VanDerWaalsContact N-OE2 3.13Å; R101-L242 HydrophobicContact CB-CD1 4.41Å; R101-L242 HydrophobicContact CB-CG 4.38Å; R101-L242 HydrophobicContact CG-CD1 4.35Å
102	R	83.3	Confident	80.5	Confident	5 Å²	5	62.1 Å²	62.1	2%	0.019	28%	0.282	C	S	.	.	S	Bend	trans	-88.5	-43.6	-173.4	-57.9	-65.6	-174.7	-162.3	-3.1	113.4	S92 D93 P104 Y105 I106 Y166 D169 E239	S92-R102 PolarHBondContact OG-NH1 3.21Å; D93-R102 IonicContact OD1-CZ 3.1Å; D93-R102 IonicContact OD1-NH1 2.76Å; D93-R102 PolarHBondContact OD1-NH1 3.11Å; D93-R102 IonicContact OD1-NH2 3.34Å; D93-R102 PolarHBondContact OD1-NH2 3.43Å; R102-P104 VanDerWaalsContact C-CD 3.49Å; R102-Y105 WeakPolarHBondContact O-CB 3.49Å; R102-Y105 PolarHBondContact O-N 2.96Å; R102-I106 HydrophobicContact CB-CD1 4.35Å; R102-I106 PolarHBondContact O-N 3.17Å; R102-I106 VanDerWaalsContact O-N 3.1Å; R102-Y166 HydrophobicContact CB-CD2 4.33Å; R102-Y166 HydrophobicContact CB-CG 4.06Å; R102-Y166 HydrophobicContact CG-CG 4.44Å; R102-D169 IonicContact CZ-OD2 3.98Å; R102-D169 IonicContact NE-OD2 3.89Å; R102-D169 PolarHBondContact NE-OD2 3.36Å; R102-D169 IonicContact NH2-OD2 3.04Å; R102-D169 PolarHBondContact NH2-OD2 3Å; R102-E239 WeakPolarHBondContact CG-OE1 3.3Å; R102-E239 PolarHBondContact N-OE1 2.65Å; R102-E239 PolarHBondContact N-OE2 2.74Å
103	R	86.3	Confident	81.6	Confident	38 Å²	38	62 Å²	62	14%	0.143	28%	0.281	C	S	.	.	H	α-helix	trans	-47.9	-47.9	-177.4	-73.1	176.8	165	-153.8	-7.3	115.7	W99 Y105 I106 L107 Y166 L234 I237 S238 E239	W99-R103 WeakPolarHBondContact O-CD 3.45Å; R103-Y105 VanDerWaalsContact C-N 3.29Å; R103-Y105 PolarHBondContact O-N 3.25Å; R103-I106 PolarHBondContact O-N 3.5Å; R103-L107 WeakPolarHBondContact O-CB 3.3Å; R103-L107 PolarHBondContact O-N 2.99Å; R103-Y166 HydrophobicContact CG-CE1 4.15Å; R103-Y166 PolarHBondContact NE-OH 3.27Å; R103-Y166 PolarHBondContact NH2-OH 2.71Å; R103-Y166 VanDerWaalsContact NH2-OH 3.16Å; R103-L234 HydrophobicContact CB-CD2 4.11Å; R103-L234 HydrophobicContact CG-CD2 4.14Å; R103-L234 PolarHBondContact NH1-O 2.94Å; R103-L234 PolarHBondContact NH2-O 2.81Å; R103-I237 PolarHBondContact NH2-O 3.37Å; R103-S238 VanDerWaalsContact NH2-CA 3.34Å; R103-E239 PolarHBondContact N-OE2 3.31Å
104	P	86.2	Confident	83	Confident	23 Å²	23	62.6 Å²	62.6	15%	0.149	29%	0.285	C	S	.	.	H	α-helix	trans	-64.2	-32.9	179.9	24.8	-35.7	0	0	0	113.2	G100 R102 T108	G100-P104 WeakPolarHBondContact O-CD 3.07Å; R102-P104 VanDerWaalsContact C-CD 3.49Å; P104-T108 WeakPolarHBondContact O-CB 3.04Å; P104-T108 PolarHBondContact O-N 3.04Å; P104-T108 PolarHBondContact O-OG1 3.38Å
105	Y	86.3	Confident	84.5	Confident	61 Å²	61	59.9 Å²	59.9	24%	0.239	28%	0.276	C	S	.	.	H	α-helix	trans	-70.1	-44.8	176.2	-82.9	-97.6	0	0	0	111.1	V88 A91 C95 R102 R103 L107 T108 L109	V88-Y105 HydrophobicContact CG1-CD1 4.19Å; V88-Y105 HydrophobicContact CG1-CE1 4.38Å; A91-Y105 VanDerWaalsContact C-CZ 3.47Å; A91-Y105 HydrophobicContact CB-CE1 4.03Å; A91-Y105 VanDerWaalsContact CB-OH 3.27Å; A91-Y105 WeakPolarHBondContact CB-OH 3.4Å; A91-Y105 PolarHBondContact O-OH 2.94Å; C95-Y105 HydrophobicContact CB-CD2 4.08Å; C95-Y105 HydrophobicContact CB-CE2 3.54Å; R102-Y105 WeakPolarHBondContact O-CB 3.49Å; R102-Y105 PolarHBondContact O-N 2.96Å; R103-Y105 VanDerWaalsContact C-N 3.29Å; R103-Y105 PolarHBondContact O-N 3.25Å; Y105-L107 VanDerWaalsContact C-N 3.33Å; Y105-L107 PolarHBondContact O-N 3.14Å; Y105-T108 PolarHBondContact O-N 3.34Å; Y105-L109 WeakPolarHBondContact O-CB 3.24Å; Y105-L109 WeakPolarHBondContact O-CG 3.49Å; Y105-L109 PolarHBondContact O-N 2.85Å
106	I	90.2	Very high	85.8	Confident	0 Å²	0	58.8 Å²	58.8	0%	0	27%	0.269	C	S	.	.	H	α-helix	trans	-59.6	-45.2	176	-64	172.2	0	0	0	110.4	R102 R103 L109 G110 I159 P162 I163 Y166 F230 L234	R102-I106 HydrophobicContact CB-CD1 4.35Å; R102-I106 PolarHBondContact O-N 3.17Å; R102-I106 VanDerWaalsContact O-N 3.1Å; R103-I106 PolarHBondContact O-N 3.5Å; I106-L109 PolarHBondContact O-N 3.23Å; I106-G110 PolarHBondContact O-N 2.93Å; I106-I159 HydrophobicContact CG2-CD1 3.91Å; I106-I159 HydrophobicContact CG2-CG1 4.26Å; I106-P162 HydrophobicContact CD1-CB 4.47Å; I106-P162 HydrophobicContact CG1-CB 3.88Å; I106-I163 HydrophobicContact CD1-CG1 4.01Å; I106-I163 HydrophobicContact CG1-CG1 4.22Å; I106-I163 HydrophobicContact CG2-CG1 4.27Å; I106-Y166 HydrophobicContact CD1-CD1 3.65Å; I106-Y166 HydrophobicContact CD1-CE1 4.44Å; I106-Y166 HydrophobicContact CD1-CG 4.32Å; I106-F230 HydrophobicContact CG2-CD1 4.46Å; I106-F230 HydrophobicContact CG2-CE1 4.29Å; I106-L234 HydrophobicContact CG2-CD2 4.41Å
107	L	92.9	Very high	87.2	Confident	63 Å²	63	48.6 Å²	48.6	33%	0.33	23%	0.23	S	C	.	.	H	α-helix	trans	-62.6	-44.7	176.2	178.8	63	0	0	0	111.9	W99 R103 Y105 L109 G110 V111 L234	W99-L107 HydrophobicContact CZ3-CD2 3.99Å; R103-L107 WeakPolarHBondContact O-CB 3.3Å; R103-L107 PolarHBondContact O-N 2.99Å; Y105-L107 VanDerWaalsContact C-N 3.33Å; Y105-L107 PolarHBondContact O-N 3.14Å; L107-L109 PolarHBondContact O-N 3.02Å; L107-G110 PolarHBondContact O-N 3.1Å; L107-V111 HydrophobicContact CD1-CG2 4.28Å; L107-V111 WeakPolarHBondContact O-CG2 3.22Å; L107-V111 PolarHBondContact O-N 3.01Å; L107-L234 HydrophobicContact CB-CD1 4.1Å; L107-L234 HydrophobicContact CD1-CD1 3.78Å; L107-L234 HydrophobicContact CG-CD1 4.41Å
108	T	92.3	Very high	88.2	Confident	86 Å²	86	48 Å²	48	53%	0.528	23%	0.228	S	C	.	.	H	α-helix	trans	-61.9	-44.2	179.4	-58.1	0	0	0	0	111.2	P104 Y105 V111 M112	P104-T108 WeakPolarHBondContact O-CB 3.04Å; P104-T108 PolarHBondContact O-N 3.04Å; P104-T108 PolarHBondContact O-OG1 3.38Å; Y105-T108 PolarHBondContact O-N 3.34Å; T108-V111 PolarHBondContact O-N 3.47Å; T108-M112 WeakPolarHBondContact O-CB 3.4Å; T108-M112 PolarHBondContact O-N 3.33Å
109	L	92.7	Very high	89.6	Confident	8 Å²	8	39.1 Å²	39.1	4%	0.042	20%	0.198	C	C	.	.	H	α-helix	trans	-66.5	-38.8	175.9	-69.4	168.4	0	0	0	111.4	Y105 I106 L107 M112 M113 A155 F158 I159 P162	Y105-L109 WeakPolarHBondContact O-CB 3.24Å; Y105-L109 WeakPolarHBondContact O-CG 3.49Å; Y105-L109 PolarHBondContact O-N 2.85Å; I106-L109 PolarHBondContact O-N 3.23Å; L107-L109 PolarHBondContact O-N 3.02Å; L109-M112 HydrophobicContact CD2-SD 4.46Å; L109-M112 CarbonylContact O-C 3.5Å; L109-M112 WeakPolarHBondContact O-CB 3.46Å; L109-M112 PolarHBondContact O-N 2.85Å; L109-M113 WeakPolarHBondContact O-CG 3.4Å; L109-M113 PolarHBondContact O-N 2.97Å; L109-A155 HydrophobicContact CD2-CB 4.45Å; L109-F158 HydrophobicContact CD1-CB 4.09Å; L109-F158 HydrophobicContact CD2-CB 3.97Å; L109-I159 HydrophobicContact CB-CB 4.07Å; L109-I159 HydrophobicContact CB-CD1 3.99Å; L109-I159 HydrophobicContact CB-CG1 3.88Å; L109-I159 HydrophobicContact CD1-CB 4.07Å; L109-I159 HydrophobicContact CD1-CG1 4.07Å; L109-P162 HydrophobicContact CD1-CG 4.32Å
110	G	95	Very high	90.7	Very high	3 Å²	3	30.9 Å²	30.9	3%	0.031	17%	0.167	C	C	.	.	H	α-helix	trans	-62.3	-42.7	173.9	0	0	0	0	0	113.9	I106 L107 M112 M113 L114	I106-G110 PolarHBondContact O-N 2.93Å; L107-G110 PolarHBondContact O-N 3.1Å; G110-M112 VanDerWaalsContact C-N 3.32Å; G110-M113 WeakPolarHBondContact O-CB 3.44Å; G110-M113 PolarHBondContact O-N 3.42Å; G110-L114 PolarHBondContact O-N 3.17Å
111	V	96	Very high	91.6	Very high	73 Å²	73	31.2 Å²	31.2	44%	0.442	17%	0.168	S	C	.	.	H	α-helix	trans	-65.3	-39.4	173	172.8	0	0	0	0	110.5	L107 T108 M113 L114 V115	L107-V111 HydrophobicContact CD1-CG2 4.28Å; L107-V111 WeakPolarHBondContact O-CG2 3.22Å; L107-V111 PolarHBondContact O-N 3.01Å; T108-V111 PolarHBondContact O-N 3.47Å; V111-M113 VanDerWaalsContact C-N 3.34Å; V111-M113 PolarHBondContact O-N 3.18Å; V111-L114 PolarHBondContact O-N 3.19Å; V111-V115 HydrophobicContact CG1-CG2 4.34Å; V111-V115 VanDerWaalsContact O-CG2 3.32Å; V111-V115 WeakPolarHBondContact O-CG2 3.42Å; V111-V115 PolarHBondContact O-N 2.86Å
112	M	95.3	Very high	92.1	Very high	53 Å²	53	30 Å²	30	26%	0.261	17%	0.165	S	C	.	.	H	α-helix	trans	-62	-39.7	175.1	-172.4	179.3	-75.3	0	0	112	T108 L109 G110 V115 G116 L151 F154 A155	T108-M112 WeakPolarHBondContact O-CB 3.4Å; T108-M112 PolarHBondContact O-N 3.33Å; L109-M112 HydrophobicContact CD2-SD 4.46Å; L109-M112 CarbonylContact O-C 3.5Å; L109-M112 WeakPolarHBondContact O-CB 3.46Å; L109-M112 PolarHBondContact O-N 2.85Å; G110-M112 VanDerWaalsContact C-N 3.32Å; M112-V115 PolarHBondContact O-N 3.22Å; M112-G116 PolarHBondContact O-N 3.21Å; M112-L151 HydrophobicContact CE-CD1 4.22Å; M112-L151 HydrophobicContact CG-CD1 3.43Å; M112-L151 VanDerWaalsContact CG-CD1 3.43Å; M112-L151 HydrophobicContact CG-CD2 4.19Å; M112-L151 HydrophobicContact CG-CG 3.61Å; M112-L151 HydrophobicContact SD-CD1 3.56Å; M112-L151 VanDerWaalsContact SD-CD1 3.56Å; M112-L151 HydrophobicContact SD-CG 4.35Å; M112-F154 HydrophobicContact SD-CD1 3.73Å; M112-F154 HydrophobicContact SD-CE1 3.94Å; M112-A155 HydrophobicContact CB-CB 3.85Å; M112-A155 HydrophobicContact CG-CB 3.74Å; M112-A155 HydrophobicContact SD-CB 3.91Å
113	M	95.8	Very high	92.2	Very high	0 Å²	0	29.8 Å²	29.8	0%	0	16%	0.164	C	C	.	.	H	α-helix	trans	-60.9	-48	170.7	-68.6	178.5	70.2	0	0	111.2	R45 C48 L109 G110 V111 V115 G116 M117 F152 A155 A156 I159 L226 F230	R45-M113 HydrophobicContact CB-CE 4.42Å; R45-M113 HydrophobicContact CG-CE 4.15Å; C48-M113 HydrophobicContact CB-CE 4.42Å; L109-M113 WeakPolarHBondContact O-CG 3.4Å; L109-M113 PolarHBondContact O-N 2.97Å; G110-M113 WeakPolarHBondContact O-CB 3.44Å; G110-M113 PolarHBondContact O-N 3.42Å; V111-M113 VanDerWaalsContact C-N 3.34Å; V111-M113 PolarHBondContact O-N 3.18Å; M113-V115 VanDerWaalsContact C-N 3.3Å; M113-V115 PolarHBondContact O-N 3.42Å; M113-G116 PolarHBondContact O-N 3.38Å; M113-M117 VanDerWaalsContact O-CB 3.3Å; M113-M117 WeakPolarHBondContact O-CB 3.45Å; M113-M117 PolarHBondContact O-N 3.1Å; M113-F152 HydrophobicContact CB-CD2 4.08Å; M113-F152 HydrophobicContact CB-CE2 4.06Å; M113-F152 HydrophobicContact CE-CE2 3.67Å; M113-F152 HydrophobicContact CE-CZ 3.76Å; M113-F152 HydrophobicContact CG-CE2 4.44Å; M113-F152 WeakPolarHBondContact O-CD2 3.26Å; M113-A155 HydrophobicContact CB-CB 4.39Å; M113-A155 HydrophobicContact CG-CB 3.47Å; M113-A155 VanDerWaalsContact CG-CB 3.47Å; M113-A156 HydrophobicContact CE-CB 3.79Å; M113-A156 HydrophobicContact SD-CB 4.31Å; M113-I159 HydrophobicContact SD-CG2 4.35Å; M113-L226 HydrophobicContact CB-CD2 3.9Å; M113-L226 HydrophobicContact CE-CD1 4.19Å; M113-L226 HydrophobicContact CE-CD2 4.4Å; M113-F230 HydrophobicContact SD-CZ 4.17Å
114	L	96.4	Very high	92	Very high	45 Å²	45	30.1 Å²	30.1	24%	0.236	18%	0.176	C	C	.	.	H	α-helix	trans	-59	-41.7	177	-73.9	171.3	0	0	0	112.3	G110 V111 A118 A223 L226	G110-L114 PolarHBondContact O-N 3.17Å; V111-L114 PolarHBondContact O-N 3.19Å; L114-A118 VanDerWaalsContact O-CB 3.3Å; L114-A118 WeakPolarHBondContact O-CB 3.4Å; L114-A118 PolarHBondContact O-N 3.42Å; L114-A223 HydrophobicContact CD2-CB 3.75Å; L114-L226 HydrophobicContact CD2-CB 4.39Å; L114-L226 HydrophobicContact CD2-CD2 3.8Å; L114-L226 HydrophobicContact CD2-CG 4.47Å; L114-L226 HydrophobicContact CG-CD2 3.89Å
115	V	96.4	Very high	92	Very high	66 Å²	66	32.2 Å²	32.2	40%	0.4	19%	0.188	S	C	.	.	H	α-helix	trans	-66.9	-48.3	176.9	172.4	0	0	0	0	110.8	V111 M112 M113 M117 A118 L119 L151	V111-V115 HydrophobicContact CG1-CG2 4.34Å; V111-V115 VanDerWaalsContact O-CG2 3.32Å; V111-V115 WeakPolarHBondContact O-CG2 3.42Å; V111-V115 PolarHBondContact O-N 2.86Å; M112-V115 PolarHBondContact O-N 3.22Å; M113-V115 VanDerWaalsContact C-N 3.3Å; M113-V115 PolarHBondContact O-N 3.42Å; V115-M117 VanDerWaalsContact C-N 3.28Å; V115-M117 PolarHBondContact O-N 2.88Å; V115-A118 PolarHBondContact O-N 3.09Å; V115-L119 HydrophobicContact CG1-CD1 3.92Å; V115-L119 HydrophobicContact CG1-CG 4.27Å; V115-L119 WeakPolarHBondContact O-CB 3.33Å; V115-L119 VanDerWaalsContact O-CG 3.23Å; V115-L119 WeakPolarHBondContact O-CG 3.05Å; V115-L119 PolarHBondContact O-N 2.9Å; V115-L151 HydrophobicContact CG1-CD2 3.99Å
116	G	95.1	Very high	92	Very high	0 Å²	0	32.3 Å²	32.3	0%	0	20%	0.195	C	C	.	.	H	α-helix	trans	-56	-46.1	176.9	0	0	0	0	0	111.5	M112 M113 L119 Y120 G148	M112-G116 PolarHBondContact O-N 3.21Å; M113-G116 PolarHBondContact O-N 3.38Å; G116-L119 PolarHBondContact O-N 3.07Å; G116-Y120 VanDerWaalsContact O-CD1 3.29Å; G116-Y120 WeakPolarHBondContact O-CD1 3.5Å; G116-Y120 PolarHBondContact O-N 3.16Å; G116-G148 CarbonylContact C-O 3.41Å; G116-G148 VanDerWaalsContact CA-O 3.25Å; G116-G148 WeakPolarHBondContact CA-O 3.43Å; G116-G148 CarbonylContact O-C 3.6Å; G116-G148 WeakPolarHBondContact O-CA 3.43Å
117	M	94.5	Very high	91.9	Very high	0 Å²	0	32.5 Å²	32.5	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-62.6	-45.5	176	-168.8	-172.6	-68.7	0	0	113.5	C48 M113 V115 L119 Y120 L121 F152 F219 S222	C48-M117 HydrophobicContact CB-CE 3.52Å; C48-M117 VanDerWaalsContact SG-CE 3.51Å; M113-M117 VanDerWaalsContact O-CB 3.3Å; M113-M117 WeakPolarHBondContact O-CB 3.45Å; M113-M117 PolarHBondContact O-N 3.1Å; V115-M117 VanDerWaalsContact C-N 3.28Å; V115-M117 PolarHBondContact O-N 2.88Å; M117-L119 VanDerWaalsContact C-N 3.26Å; M117-L119 PolarHBondContact O-N 3.38Å; M117-Y120 VanDerWaalsContact CA-CD1 3.49Å; M117-Y120 VanDerWaalsContact CA-CE1 3.43Å; M117-Y120 HydrophobicContact CB-CD1 4.49Å; M117-Y120 HydrophobicContact CB-CE1 3.96Å; M117-Y120 HydrophobicContact CG-CE1 3.82Å; M117-Y120 PolarHBondContact O-N 3.06Å; M117-L121 HydrophobicContact CG-CD1 3.61Å; M117-L121 HydrophobicContact CG-CG 4.31Å; M117-L121 WeakPolarHBondContact O-CB 3.42Å; M117-L121 PolarHBondContact O-N 3.05Å; M117-L121 HydrophobicContact SD-CD1 4.22Å; M117-F152 HydrophobicContact CB-CD2 4.01Å; M117-F152 HydrophobicContact CB-CE2 4.4Å; M117-F152 HydrophobicContact CE-CD2 4.24Å; M117-F152 HydrophobicContact CE-CE2 3.55Å; M117-F152 HydrophobicContact CE-CZ 4.2Å; M117-F219 HydrophobicContact CB-CD2 4.45Å; M117-F219 HydrophobicContact CB-CE2 4.49Å; M117-F219 HydrophobicContact CG-CD2 3.87Å; M117-F219 HydrophobicContact CG-CE2 4.37Å; M117-F219 HydrophobicContact SD-CD2 3.99Å; M117-F219 HydrophobicContact SD-CE2 4.5Å; M117-S222 WeakPolarHBondContact SD-CB 3.4Å
118	A	94	Very high	91.6	Very high	30 Å²	30	31.5 Å²	31.5	25%	0.248	20%	0.197	C	C	.	.	H	α-helix	trans	-58.4	-42.6	175.2	0	0	0	0	0	110.8	L114 V115 N122 F219	L114-A118 VanDerWaalsContact O-CB 3.3Å; L114-A118 WeakPolarHBondContact O-CB 3.4Å; L114-A118 PolarHBondContact O-N 3.42Å; V115-A118 PolarHBondContact O-N 3.09Å; A118-N122 WeakPolarHBondContact O-CA 3.47Å; A118-N122 WeakPolarHBondContact O-CB 3.36Å; A118-N122 PolarHBondContact O-N 3.12Å; A118-N122 PolarHBondContact O-ND2 3.49Å; A118-F219 VanDerWaalsContact CA-CE2 3.48Å; A118-F219 HydrophobicContact CB-CE2 3.63Å; A118-F219 HydrophobicContact CB-CZ 3.76Å
119	L	93.2	Very high	91.4	Very high	47 Å²	47	31.6 Å²	31.6	25%	0.246	21%	0.206	C	C	.	.	H	α-helix	trans	-69.3	-41.8	-179.6	-68	175.7	0	0	0	113	V115 G116 M117 G123 V144 L151	V115-L119 HydrophobicContact CG1-CD1 3.92Å; V115-L119 HydrophobicContact CG1-CG 4.27Å; V115-L119 WeakPolarHBondContact O-CB 3.33Å; V115-L119 VanDerWaalsContact O-CG 3.23Å; V115-L119 WeakPolarHBondContact O-CG 3.05Å; V115-L119 PolarHBondContact O-N 2.9Å; G116-L119 PolarHBondContact O-N 3.07Å; M117-L119 VanDerWaalsContact C-N 3.26Å; M117-L119 PolarHBondContact O-N 3.38Å; L119-G123 WeakPolarHBondContact O-CA 3.23Å; L119-G123 PolarHBondContact O-N 3.03Å; L119-V144 HydrophobicContact CB-CG1 4.36Å; L119-V144 HydrophobicContact CD2-CG1 3.95Å; L119-L151 HydrophobicContact CD1-CD2 4.38Å
120	Y	92.4	Very high	91.3	Very high	1 Å²	1	37.8 Å²	37.8	0%	0.004	24%	0.238	C	C	.	.	H	α-helix	trans	-78.2	-42.1	-178.7	84.8	-104.4	0	0	0	112.7	V59 G116 M117 V149 F152	V59-Y120 HydrophobicContact CG1-CD2 4.37Å; V59-Y120 VanDerWaalsContact CG1-O 3.28Å; V59-Y120 WeakPolarHBondContact CG1-O 3.34Å; G116-Y120 VanDerWaalsContact O-CD1 3.29Å; G116-Y120 WeakPolarHBondContact O-CD1 3.5Å; G116-Y120 PolarHBondContact O-N 3.16Å; M117-Y120 VanDerWaalsContact CA-CD1 3.49Å; M117-Y120 VanDerWaalsContact CA-CE1 3.43Å; M117-Y120 HydrophobicContact CB-CD1 4.49Å; M117-Y120 HydrophobicContact CB-CE1 3.96Å; M117-Y120 HydrophobicContact CG-CE1 3.82Å; M117-Y120 PolarHBondContact O-N 3.06Å; Y120-V149 HydrophobicContact CD1-CG2 4.5Å; Y120-V149 HydrophobicContact CD2-CG2 4.43Å; Y120-V149 HydrophobicContact CG-CG2 3.99Å; Y120-F152 HydrophobicContact CD1-CB 4.38Å; Y120-F152 HydrophobicContact CE1-CB 4.36Å; Y120-F152 HydrophobicContact CE1-CD2 4.44Å; Y120-F152 HydrophobicContact CE1-CG 4.19Å
121	L	90.4	Very high	90.9	Very high	8 Å²	8	39.3 Å²	39.3	4%	0.042	25%	0.246	C	C	.	.	H	α-helix	trans	-73.8	-30.6	179.4	-68.3	174.9	0	0	0	113.1	V59 M117 F215 M218 F219	V59-L121 HydrophobicContact CG2-CD2 4.15Å; M117-L121 HydrophobicContact CG-CD1 3.61Å; M117-L121 HydrophobicContact CG-CG 4.31Å; M117-L121 WeakPolarHBondContact O-CB 3.42Å; M117-L121 PolarHBondContact O-N 3.05Å; M117-L121 HydrophobicContact SD-CD1 4.22Å; L121-F215 HydrophobicContact CB-CB 4.42Å; L121-F215 HydrophobicContact CD2-CB 4.12Å; L121-F215 HydrophobicContact CD2-CD1 4.48Å; L121-M218 HydrophobicContact CD1-CB 4.28Å; L121-F219 HydrophobicContact CB-CB 4.19Å; L121-F219 HydrophobicContact CD1-CB 3.61Å; L121-F219 HydrophobicContact CD1-CD2 4.3Å; L121-F219 HydrophobicContact CD1-CG 4.45Å
122	N	89.8	Confident	90.4	Very high	19 Å²	19	40.7 Å²	40.7	10%	0.102	26%	0.264	C	S	.	.	H	α-helix	trans	-113.9	4.3	-177.3	-54.3	-89.4	0	0	0	113.5	A118 A124 T125 V126 Q216	A118-N122 WeakPolarHBondContact O-CA 3.47Å; A118-N122 WeakPolarHBondContact O-CB 3.36Å; A118-N122 PolarHBondContact O-N 3.12Å; A118-N122 PolarHBondContact O-ND2 3.49Å; N122-A124 VanDerWaalsContact C-N 3.33Å; N122-A124 PolarHBondContact O-N 3.45Å; N122-T125 WeakPolarHBondContact O-CA 3.45Å; N122-T125 PolarHBondContact O-N 3.36Å; N122-T125 PolarHBondContact O-OG1 2.86Å; N122-V126 HydrophobicContact CB-CG2 4.35Å; N122-V126 WeakPolarHBondContact O-CG2 3.31Å; N122-V126 PolarHBondContact O-N 3.1Å; N122-Q216 WeakPolarHBondContact OD1-CG 3.48Å
123	G	85.1	Confident	90.1	Very high	1 Å²	1	42.6 Å²	42.6	1%	0.01	28%	0.276	C	S	.	.	H	α-helix	trans	-54.4	-44.2	-171.5	0	0	0	0	0	113.9	L119 T125 V126 V127	L119-G123 WeakPolarHBondContact O-CA 3.23Å; L119-G123 PolarHBondContact O-N 3.03Å; G123-T125 VanDerWaalsContact C-N 3.34Å; G123-T125 PolarHBondContact O-N 3.36Å; G123-V126 PolarHBondContact O-N 2.98Å; G123-V127 WeakPolarHBondContact O-CB 3.27Å; G123-V127 VanDerWaalsContact O-CG2 3.27Å; G123-V127 WeakPolarHBondContact O-CG2 3.38Å; G123-V127 PolarHBondContact O-N 3.32Å
124	A	82.5	Confident	89.5	Confident	46 Å²	46	47.8 Å²	47.8	38%	0.38	31%	0.309	S	S	.	.	H	α-helix	trans	-61.7	-40.1	176.4	0	0	0	0	0	112.7	V63 N122 A128	V63-A124 HydrophobicContact CG2-CB 4.27Å; N122-A124 VanDerWaalsContact C-N 3.33Å; N122-A124 PolarHBondContact O-N 3.45Å; A124-A128 WeakPolarHBondContact O-CB 3.35Å; A124-A128 PolarHBondContact O-N 2.86Å
125	T	85.3	Confident	88.9	Confident	66 Å²	66	56.1 Å²	56.1	41%	0.405	34%	0.338	S	S	.	.	H	α-helix	trans	-70.4	-42.4	179.3	68.7	0	0	0	0	111.8	N122 G123 A128 A129	N122-T125 WeakPolarHBondContact O-CA 3.45Å; N122-T125 PolarHBondContact O-N 3.36Å; N122-T125 PolarHBondContact O-OG1 2.86Å; G123-T125 VanDerWaalsContact C-N 3.34Å; G123-T125 PolarHBondContact O-N 3.36Å; T125-A128 PolarHBondContact O-N 3.06Å; T125-A129 PolarHBondContact O-N 2.93Å; T125-A129 VanDerWaalsContact O-N 3.11Å
126	V	86.4	Confident	88.5	Confident	63 Å²	63	60.7 Å²	60.7	38%	0.382	35%	0.348	S	S	.	.	H	α-helix	trans	-63.4	-46.5	176.9	174.4	0	0	0	0	110.3	N122 G123 A129 L130	N122-V126 HydrophobicContact CB-CG2 4.35Å; N122-V126 WeakPolarHBondContact O-CG2 3.31Å; N122-V126 PolarHBondContact O-N 3.1Å; G123-V126 PolarHBondContact O-N 2.98Å; V126-A129 PolarHBondContact O-N 3.32Å; V126-L130 HydrophobicContact CG1-CD1 4.09Å; V126-L130 WeakPolarHBondContact O-CG 3.46Å; V126-L130 PolarHBondContact O-N 3.34Å
127	V	89.1	Confident	88.1	Confident	5 Å²	5	64.9 Å²	64.9	3%	0.03	37%	0.366	C	S	.	.	H	α-helix	trans	-68.2	-37	178.5	173.3	0	0	0	0	111.6	G123 A129 L130 I131 K137 W140 A141 V144	G123-V127 WeakPolarHBondContact O-CB 3.27Å; G123-V127 VanDerWaalsContact O-CG2 3.27Å; G123-V127 WeakPolarHBondContact O-CG2 3.38Å; G123-V127 PolarHBondContact O-N 3.32Å; V127-A129 VanDerWaalsContact C-N 3.25Å; V127-A129 PolarHBondContact O-N 3.3Å; V127-L130 PolarHBondContact O-N 3.36Å; V127-I131 HydrophobicContact CG1-CB 4.39Å; V127-I131 HydrophobicContact CG1-CD1 4.02Å; V127-I131 HydrophobicContact CG1-CG1 4.33Å; V127-I131 PolarHBondContact O-N 2.86Å; V127-K137 HydrophobicContact CG1-CG 4.25Å; V127-K137 WeakPolarHBondContact CG1-O 3.34Å; V127-W140 HydrophobicContact CG1-CB 3.59Å; V127-W140 HydrophobicContact CG2-CB 4.24Å; V127-A141 HydrophobicContact CB-CB 4.33Å; V127-A141 HydrophobicContact CG1-CB 4.29Å; V127-V144 HydrophobicContact CG2-CB 3.96Å; V127-V144 HydrophobicContact CG2-CG1 4.39Å; V127-V144 HydrophobicContact CG2-CG2 3.67Å
128	A	86.3	Confident	87.8	Confident	41 Å²	41	69.3 Å²	69.3	34%	0.339	39%	0.389	S	S	.	.	H	α-helix	trans	-60.1	-35.4	175.2	0	0	0	0	0	112.9	A124 T125 K137	A124-A128 WeakPolarHBondContact O-CB 3.35Å; A124-A128 PolarHBondContact O-N 2.86Å; T125-A128 PolarHBondContact O-N 3.06Å; A128-K137 HydrophobicContact CB-CD 4.49Å; A128-K137 VanDerWaalsContact CB-CE 3.41Å
129	A	87.8	Confident	87.5	Confident	88 Å²	88	71.9 Å²	71.9	73%	0.727	40%	0.402	S	S	*	.	H	α-helix	trans	-73.6	-28.7	177.4	0	0	0	0	0	113	T125 V126 V127	T125-A129 PolarHBondContact O-N 2.93Å; T125-A129 VanDerWaalsContact O-N 3.11Å; V126-A129 PolarHBondContact O-N 3.32Å; V127-A129 VanDerWaalsContact C-N 3.25Å; V127-A129 PolarHBondContact O-N 3.3Å
130	L	89.9	Confident	87.4	Confident	138 Å²	138	76.2 Å²	76.2	72%	0.723	42%	0.415	S	S	*	.	H	α-helix	trans	-95.8	-27.5	-174.5	-65.5	173.3	0	0	0	114	V126 V127	V126-L130 HydrophobicContact CG1-CD1 4.09Å; V126-L130 WeakPolarHBondContact O-CG 3.46Å; V126-L130 PolarHBondContact O-N 3.34Å; V127-L130 PolarHBondContact O-N 3.36Å
131	I	87.9	Confident	87.3	Confident	36 Å²	36	76.6 Å²	76.6	19%	0.185	42%	0.418	C	S	.	.			trans	-126.7	112.2	-169.8	-54.2	-174.1	0	0	0	111.1	V127 N133 R136 K137 W140	V127-I131 HydrophobicContact CG1-CB 4.39Å; V127-I131 HydrophobicContact CG1-CD1 4.02Å; V127-I131 HydrophobicContact CG1-CG1 4.33Å; V127-I131 PolarHBondContact O-N 2.86Å; I131-N133 HydrophobicContact CG2-CB 4.45Å; I131-R136 HydrophobicContact CG2-CB 3.82Å; I131-K137 HydrophobicContact CG2-CB 4.35Å; I131-W140 HydrophobicContact CD1-CB 3.55Å; I131-W140 HydrophobicContact CD1-CD2 3.95Å; I131-W140 HydrophobicContact CD1-CG 3.28Å
132	A	85.1	Confident	87.2	Confident	101 Å²	101	77.4 Å²	77.4	84%	0.835	42%	0.422	S	S	*	.			trans	-77.7	-30	177.1	0	0	0	0	0	113.8
133	N	87.8	Confident	87.2	Confident	94 Å²	94	78.7 Å²	78.7	50%	0.503	43%	0.432	S	S	.	.			trans	-72.1	120.3	-174.6	-76.7	-40.5	0	0	0	111.6	I131 R135 R136 K137	I131-N133 HydrophobicContact CG2-CB 4.45Å; N133-R135 PolarHBondContact O-N 3.04Å; N133-R136 HydrophobicContact CB-CB 4.08Å; N133-R136 HydrophobicContact CB-CG 4.19Å; N133-R136 PolarHBondContact O-N 3.47Å; N133-K137 WeakPolarHBondContact O-CB 3.26Å; N133-K137 PolarHBondContact O-N 3.37Å
134	P	83.2	Confident	87.5	Confident	108 Å²	108	79.9 Å²	79.9	70%	0.701	44%	0.44	S	S	*	.	H	α-helix	trans	-62.8	-43.5	-169	21.8	-33.1	0	0	0	113.8	R136 K137 L138	P134-R136 PolarHBondContact O-N 2.89Å; P134-K137 WeakPolarHBondContact O-CB 3.11Å; P134-K137 PolarHBondContact O-N 2.91Å; P134-L138 PolarHBondContact O-N 3.16Å; P134-L138 VanDerWaalsContact O-N 3.12Å
135	R	85	Confident	88	Confident	220 Å²	220	77.7 Å²	77.7	83%	0.83	42%	0.422	S	S	*	.	H	α-helix	trans	-65.3	-39.2	178.5	-165.9	-179.8	-166.4	-173.8	4.9	112.3	N133 V139	N133-R135 PolarHBondContact O-N 3.04Å; R135-V139 WeakPolarHBondContact O-CG2 3.45Å; R135-V139 PolarHBondContact O-N 3.39Å
136	R	87.5	Confident	88.2	Confident	162 Å²	162	76.7 Å²	76.7	61%	0.611	41%	0.413	S	S	*	.	H	α-helix	trans	-71	-40.9	176.6	-65.2	-171	-169.6	-158.9	2.1	110.2	I131 N133 P134 L138 V139 W140	I131-R136 HydrophobicContact CG2-CB 3.82Å; N133-R136 HydrophobicContact CB-CB 4.08Å; N133-R136 HydrophobicContact CB-CG 4.19Å; N133-R136 PolarHBondContact O-N 3.47Å; P134-R136 PolarHBondContact O-N 2.89Å; R136-L138 VanDerWaalsContact C-N 3.31Å; R136-L138 PolarHBondContact O-N 3.3Å; R136-V139 PolarHBondContact O-N 3.11Å; R136-W140 WeakPolarHBondContact O-CB 3.45Å; R136-W140 PolarHBondContact O-N 3.24Å
137	K	87	Confident	88.4	Confident	88 Å²	88	78.5 Å²	78.5	38%	0.383	42%	0.419	S	S	.	.	H	α-helix	trans	-54.6	-46.4	177.8	-179.1	178.3	172.6	172.8	0	111.4	V127 A128 I131 N133 P134 A141	V127-K137 HydrophobicContact CG1-CG 4.25Å; V127-K137 WeakPolarHBondContact CG1-O 3.34Å; A128-K137 HydrophobicContact CB-CD 4.49Å; A128-K137 VanDerWaalsContact CB-CE 3.41Å; I131-K137 HydrophobicContact CG2-CB 4.35Å; N133-K137 WeakPolarHBondContact O-CB 3.26Å; N133-K137 PolarHBondContact O-N 3.37Å; P134-K137 WeakPolarHBondContact O-CB 3.11Å; P134-K137 PolarHBondContact O-N 2.91Å; K137-A141 WeakPolarHBondContact O-CB 3.28Å; K137-A141 PolarHBondContact O-N 2.92Å
138	L	87.1	Confident	88.6	Confident	93 Å²	93	78.3 Å²	78.3	49%	0.487	42%	0.418	S	S	.	.	H	α-helix	trans	-60.3	-53.1	176.1	-178.8	65.2	0	0	0	112	V63 P134 R136 W140 A141 I142	V63-L138 WeakPolarHBondContact O-CD1 3.26Å; P134-L138 PolarHBondContact O-N 3.16Å; P134-L138 VanDerWaalsContact O-N 3.12Å; R136-L138 VanDerWaalsContact C-N 3.31Å; R136-L138 PolarHBondContact O-N 3.3Å; L138-W140 VanDerWaalsContact C-N 3.33Å; L138-W140 PolarHBondContact O-N 3.43Å; L138-A141 PolarHBondContact O-N 3.38Å; L138-I142 HydrophobicContact CD1-CD1 4.06Å; L138-I142 HydrophobicContact CD1-CG1 4.41Å; L138-I142 HydrophobicContact CG-CD1 4.05Å; L138-I142 WeakPolarHBondContact O-CG1 3.25Å; L138-I142 PolarHBondContact O-N 2.88Å
139	V	88.4	Confident	88.9	Confident	84 Å²	84	76.4 Å²	76.4	51%	0.509	40%	0.402	S	S	.	.	H	α-helix	trans	-60	-43.9	-178.2	174.5	0	0	0	0	111.6	R135 R136 S143	R135-V139 WeakPolarHBondContact O-CG2 3.45Å; R135-V139 PolarHBondContact O-N 3.39Å; R136-V139 PolarHBondContact O-N 3.11Å; V139-S143 WeakPolarHBondContact O-CB 3.42Å; V139-S143 PolarHBondContact O-N 3.16Å; V139-S143 PolarHBondContact O-OG 2.89Å
140	W	90.7	Very high	89.1	Confident	139 Å²	139	73.1 Å²	73.1	53%	0.527	37%	0.373	S	S	.	.	H	α-helix	trans	-70.8	-36.3	178.7	-80.6	100.9	0	0	0	112.4	V127 I131 R136 L138 S143 V144	V127-W140 HydrophobicContact CG1-CB 3.59Å; V127-W140 HydrophobicContact CG2-CB 4.24Å; I131-W140 HydrophobicContact CD1-CB 3.55Å; I131-W140 HydrophobicContact CD1-CD2 3.95Å; I131-W140 HydrophobicContact CD1-CG 3.28Å; R136-W140 WeakPolarHBondContact O-CB 3.45Å; R136-W140 PolarHBondContact O-N 3.24Å; L138-W140 VanDerWaalsContact C-N 3.33Å; L138-W140 PolarHBondContact O-N 3.43Å; W140-S143 PolarHBondContact O-N 3.29Å; W140-V144 HydrophobicContact CE3-CG2 4.48Å; W140-V144 VanDerWaalsContact O-CB 3.31Å; W140-V144 WeakPolarHBondContact O-CB 3.49Å; W140-V144 VanDerWaalsContact O-CG2 3.24Å; W140-V144 WeakPolarHBondContact O-CG2 2.99Å; W140-V144 PolarHBondContact O-N 3.25Å
141	A	90.4	Very high	89.2	Confident	8 Å²	8	68.8 Å²	68.8	7%	0.066	35%	0.35	C	S	.	.	H	α-helix	trans	-62.6	-48.7	175.7	0	0	0	0	0	110.1	V63 V127 K137 L138 S143 V144 T145	V63-A141 HydrophobicContact CG1-CB 3.63Å; V127-A141 HydrophobicContact CB-CB 4.33Å; V127-A141 HydrophobicContact CG1-CB 4.29Å; K137-A141 WeakPolarHBondContact O-CB 3.28Å; K137-A141 PolarHBondContact O-N 2.92Å; L138-A141 PolarHBondContact O-N 3.38Å; A141-S143 VanDerWaalsContact C-N 3.34Å; A141-S143 PolarHBondContact O-N 2.78Å; A141-V144 PolarHBondContact O-N 3.48Å; A141-T145 WeakPolarHBondContact O-CB 3.34Å; A141-T145 PolarHBondContact O-N 3.32Å; A141-T145 PolarHBondContact O-OG1 3.47Å; A141-T145 VanDerWaalsContact O-OG1 3.1Å
142	I	88.5	Confident	89.5	Confident	26 Å²	26	67 Å²	67	13%	0.133	34%	0.341	C	S	.	.	H	α-helix	trans	-57	-49.9	174.9	-66.2	171.1	0	0	0	110.2	V63 L65 L138 V144 T145 M146	V63-I142 HydrophobicContact CG1-CB 4.29Å; V63-I142 HydrophobicContact CG1-CG1 3.73Å; V63-I142 VanDerWaalsContact CG1-N 3.3Å; V63-I142 WeakPolarHBondContact O-CG1 3.5Å; L65-I142 HydrophobicContact CB-CG2 4.48Å; L65-I142 HydrophobicContact CD1-CG2 3.52Å; L138-I142 HydrophobicContact CD1-CD1 4.06Å; L138-I142 HydrophobicContact CD1-CG1 4.41Å; L138-I142 HydrophobicContact CG-CD1 4.05Å; L138-I142 WeakPolarHBondContact O-CG1 3.25Å; L138-I142 PolarHBondContact O-N 2.88Å; I142-V144 PolarHBondContact O-N 3.23Å; I142-T145 PolarHBondContact O-N 2.49Å; I142-M146 HydrophobicContact CG2-CG 4.25Å; I142-M146 HydrophobicContact CG2-SD 3.66Å; I142-M146 WeakPolarHBondContact O-CB 3.45Å; I142-M146 VanDerWaalsContact O-CG 3.24Å; I142-M146 WeakPolarHBondContact O-CG 3.48Å; I142-M146 PolarHBondContact O-N 3.34Å
143	S	90	Very high	89.9	Confident	45 Å²	45	62.7 Å²	62.7	32%	0.315	30%	0.304	S	S	.	.	H	α-helix	trans	-63	-45.4	-176.6	-56.7	0	0	0	0	112.4	V139 W140 A141 M146 I147	V139-S143 WeakPolarHBondContact O-CB 3.42Å; V139-S143 PolarHBondContact O-N 3.16Å; V139-S143 PolarHBondContact O-OG 2.89Å; W140-S143 PolarHBondContact O-N 3.29Å; A141-S143 VanDerWaalsContact C-N 3.34Å; A141-S143 PolarHBondContact O-N 2.78Å; S143-M146 PolarHBondContact O-N 3.16Å; S143-I147 WeakPolarHBondContact O-CB 3.09Å; S143-I147 WeakPolarHBondContact O-CD1 3.43Å; S143-I147 WeakPolarHBondContact O-CG1 3.4Å; S143-I147 PolarHBondContact O-N 2.82Å
144	V	92.6	Very high	90	Very high	27 Å²	27	59.4 Å²	59.4	16%	0.164	29%	0.286	C	S	.	.	H	α-helix	trans	-66.2	-43.4	179.9	169.2	0	0	0	0	110.9	L119 V127 W140 A141 I142 I147 G148	L119-V144 HydrophobicContact CB-CG1 4.36Å; L119-V144 HydrophobicContact CD2-CG1 3.95Å; V127-V144 HydrophobicContact CG2-CB 3.96Å; V127-V144 HydrophobicContact CG2-CG1 4.39Å; V127-V144 HydrophobicContact CG2-CG2 3.67Å; W140-V144 HydrophobicContact CE3-CG2 4.48Å; W140-V144 VanDerWaalsContact O-CB 3.31Å; W140-V144 WeakPolarHBondContact O-CB 3.49Å; W140-V144 VanDerWaalsContact O-CG2 3.24Å; W140-V144 WeakPolarHBondContact O-CG2 2.99Å; W140-V144 PolarHBondContact O-N 3.25Å; A141-V144 PolarHBondContact O-N 3.48Å; I142-V144 PolarHBondContact O-N 3.23Å; V144-I147 PolarHBondContact O-N 2.93Å; V144-G148 PolarHBondContact O-N 3.45Å
145	T	91.2	Very high	90.4	Very high	0 Å²	0	54.3 Å²	54.3	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-63.7	-46.3	176.9	-64	0	0	0	0	111	V59 L60 V63 A141 I142 I147 G148 V149	V59-T145 HydrophobicContact CG1-CG2 3.79Å; L60-T145 HydrophobicContact CD2-CG2 3.7Å; V63-T145 HydrophobicContact CG2-CG2 4.45Å; A141-T145 WeakPolarHBondContact O-CB 3.34Å; A141-T145 PolarHBondContact O-N 3.32Å; A141-T145 PolarHBondContact O-OG1 3.47Å; A141-T145 VanDerWaalsContact O-OG1 3.1Å; I142-T145 PolarHBondContact O-N 2.49Å; T145-I147 PolarHBondContact O-N 2.85Å; T145-G148 WeakPolarHBondContact O-CA 3.5Å; T145-G148 PolarHBondContact O-N 3.45Å; T145-G148 VanDerWaalsContact O-N 3.12Å; T145-V149 WeakPolarHBondContact O-CG2 3.48Å; T145-V149 PolarHBondContact O-N 2.89Å
146	M	89.5	Confident	90.8	Very high	45 Å²	45	43.8 Å²	43.8	22%	0.222	21%	0.213	C	C	.	.	H	α-helix	trans	-59.8	-44.4	175.8	-73.5	175.9	78.5	0	0	112.3	L60 L65 V73 I142 S143 G148 V149 V150	L60-M146 HydrophobicContact CD2-CG 4.19Å; L65-M146 HydrophobicContact CD1-CE 4.28Å; L65-M146 HydrophobicContact CD1-CG 4.28Å; L65-M146 HydrophobicContact CD1-SD 3.54Å; L65-M146 VanDerWaalsContact CD1-SD 3.54Å; V73-M146 HydrophobicContact CG2-CE 3.47Å; V73-M146 VanDerWaalsContact CG2-CE 3.47Å; V73-M146 HydrophobicContact CG2-CG 4.03Å; V73-M146 HydrophobicContact CG2-SD 4.49Å; I142-M146 HydrophobicContact CG2-CG 4.25Å; I142-M146 HydrophobicContact CG2-SD 3.66Å; I142-M146 WeakPolarHBondContact O-CB 3.45Å; I142-M146 VanDerWaalsContact O-CG 3.24Å; I142-M146 WeakPolarHBondContact O-CG 3.48Å; I142-M146 PolarHBondContact O-N 3.34Å; S143-M146 PolarHBondContact O-N 3.16Å; M146-G148 VanDerWaalsContact C-N 3.27Å; M146-G148 PolarHBondContact O-N 2.89Å; M146-V149 PolarHBondContact O-N 3.42Å; M146-V150 VanDerWaalsContact O-CG2 3.24Å; M146-V150 WeakPolarHBondContact O-CG2 3.39Å; M146-V150 PolarHBondContact O-N 3.03Å
147	I	91.9	Very high	90.8	Very high	101 Å²	101	36.4 Å²	36.4	52%	0.518	19%	0.185	S	C	.	.	H	α-helix	trans	-61.7	-39.7	175.5	-71.2	165	0	0	0	110.3	S143 V144 T145 L151	S143-I147 WeakPolarHBondContact O-CB 3.09Å; S143-I147 WeakPolarHBondContact O-CD1 3.43Å; S143-I147 WeakPolarHBondContact O-CG1 3.4Å; S143-I147 PolarHBondContact O-N 2.82Å; V144-I147 PolarHBondContact O-N 2.93Å; T145-I147 PolarHBondContact O-N 2.85Å; I147-L151 WeakPolarHBondContact O-CB 2.87Å; I147-L151 PolarHBondContact O-N 2.85Å
148	G	93.4	Very high	90.7	Very high	0 Å²	0	32.5 Å²	32.5	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-59.5	-48.5	176.7	0	0	0	0	0	112.9	G116 V144 T145 M146 L151 F152	G116-G148 CarbonylContact C-O 3.41Å; G116-G148 VanDerWaalsContact CA-O 3.25Å; G116-G148 WeakPolarHBondContact CA-O 3.43Å; G116-G148 CarbonylContact O-C 3.6Å; G116-G148 WeakPolarHBondContact O-CA 3.43Å; V144-G148 PolarHBondContact O-N 3.45Å; T145-G148 WeakPolarHBondContact O-CA 3.5Å; T145-G148 PolarHBondContact O-N 3.45Å; T145-G148 VanDerWaalsContact O-N 3.12Å; M146-G148 VanDerWaalsContact C-N 3.27Å; M146-G148 PolarHBondContact O-N 2.89Å; G148-L151 PolarHBondContact O-N 3.34Å; G148-F152 WeakPolarHBondContact O-CB 3.44Å; G148-F152 PolarHBondContact O-N 2.85Å
149	V	92.1	Very high	90.8	Very high	2 Å²	2	28 Å²	28	1%	0.012	15%	0.145	C	C	.	.	H	α-helix	trans	-59.6	-54.8	176.6	174.4	0	0	0	0	110.1	V56 L60 V73 Y120 T145 M146 L151 F152 D153	V56-V149 HydrophobicContact CG2-CB 4.43Å; V56-V149 HydrophobicContact CG2-CG1 3.78Å; V56-V149 HydrophobicContact CG2-CG2 3.68Å; L60-V149 HydrophobicContact CD2-CG2 4.37Å; V73-V149 HydrophobicContact CG1-CB 4.14Å; V73-V149 HydrophobicContact CG1-CG1 3.63Å; Y120-V149 HydrophobicContact CD1-CG2 4.5Å; Y120-V149 HydrophobicContact CD2-CG2 4.43Å; Y120-V149 HydrophobicContact CG-CG2 3.99Å; T145-V149 WeakPolarHBondContact O-CG2 3.48Å; T145-V149 PolarHBondContact O-N 2.89Å; M146-V149 PolarHBondContact O-N 3.42Å; V149-L151 VanDerWaalsContact C-N 3.26Å; V149-L151 PolarHBondContact O-N 3.49Å; V149-F152 PolarHBondContact O-N 3.45Å; V149-D153 PolarHBondContact O-N 3.03Å
150	V	91.6	Very high	90.7	Very high	18 Å²	18	24.4 Å²	24.4	11%	0.109	12%	0.123	C	C	.	.	H	α-helix	trans	-60	-38.5	-177.8	174.6	0	0	0	0	111.8	V73 L76 L80 M146 F154	V73-V150 HydrophobicContact CG1-CG2 4.23Å; L76-V150 HydrophobicContact CB-CG2 4.43Å; L76-V150 HydrophobicContact CD2-CG1 3.95Å; L76-V150 HydrophobicContact CD2-CG2 3.87Å; L76-V150 HydrophobicContact CG-CG1 4.09Å; L76-V150 HydrophobicContact CG-CG2 4.4Å; L80-V150 HydrophobicContact CD1-CG1 3.61Å; M146-V150 VanDerWaalsContact O-CG2 3.24Å; M146-V150 WeakPolarHBondContact O-CG2 3.39Å; M146-V150 PolarHBondContact O-N 3.03Å; V150-F154 WeakPolarHBondContact O-CB 3.36Å; V150-F154 PolarHBondContact O-N 3.25Å
151	L	93.1	Very high	90.3	Very high	47 Å²	47	18.3 Å²	18.3	25%	0.246	10%	0.103	C	C	.	.	H	α-helix	trans	-69.5	-40.3	177.7	-173.7	66.9	0	0	0	112	M112 V115 L119 I147 G148 V149 A155	M112-L151 HydrophobicContact CE-CD1 4.22Å; M112-L151 HydrophobicContact CG-CD1 3.43Å; M112-L151 VanDerWaalsContact CG-CD1 3.43Å; M112-L151 HydrophobicContact CG-CD2 4.19Å; M112-L151 HydrophobicContact CG-CG 3.61Å; M112-L151 HydrophobicContact SD-CD1 3.56Å; M112-L151 VanDerWaalsContact SD-CD1 3.56Å; M112-L151 HydrophobicContact SD-CG 4.35Å; V115-L151 HydrophobicContact CG1-CD2 3.99Å; L119-L151 HydrophobicContact CD1-CD2 4.38Å; I147-L151 WeakPolarHBondContact O-CB 2.87Å; I147-L151 PolarHBondContact O-N 2.85Å; G148-L151 PolarHBondContact O-N 3.34Å; V149-L151 VanDerWaalsContact C-N 3.26Å; V149-L151 PolarHBondContact O-N 3.49Å; L151-A155 VanDerWaalsContact O-CB 3.32Å; L151-A155 WeakPolarHBondContact O-CB 3.34Å; L151-A155 PolarHBondContact O-N 3.18Å
152	F	94.7	Very high	90	Very high	0 Å²	0	18.3 Å²	18.3	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-64.5	-54.6	176.3	176.7	-88.7	0	0	0	110.7	C48 Y49 E52 M113 M117 Y120 G148 V149 F154 A155 A156	C48-F152 HydrophobicContact CB-CE2 3.85Å; C48-F152 HydrophobicContact CB-CZ 3.52Å; Y49-F152 HydrophobicContact CD2-CE1 4.1Å; E52-F152 HydrophobicContact CB-CD1 4.47Å; E52-F152 HydrophobicContact CB-CE1 4.08Å; E52-F152 HydrophobicContact CG-CD1 4.41Å; E52-F152 HydrophobicContact CG-CE1 4.47Å; E52-F152 WeakPolarHBondContact OE1-CD1 3.34Å; E52-F152 WeakPolarHBondContact OE2-CD1 3.4Å; E52-F152 WeakPolarHBondContact OE2-CE1 3.37Å; M113-F152 HydrophobicContact CB-CD2 4.08Å; M113-F152 HydrophobicContact CB-CE2 4.06Å; M113-F152 HydrophobicContact CE-CE2 3.67Å; M113-F152 HydrophobicContact CE-CZ 3.76Å; M113-F152 HydrophobicContact CG-CE2 4.44Å; M113-F152 WeakPolarHBondContact O-CD2 3.26Å; M117-F152 HydrophobicContact CB-CD2 4.01Å; M117-F152 HydrophobicContact CB-CE2 4.4Å; M117-F152 HydrophobicContact CE-CD2 4.24Å; M117-F152 HydrophobicContact CE-CE2 3.55Å; M117-F152 HydrophobicContact CE-CZ 4.2Å; Y120-F152 HydrophobicContact CD1-CB 4.38Å; Y120-F152 HydrophobicContact CE1-CB 4.36Å; Y120-F152 HydrophobicContact CE1-CD2 4.44Å; Y120-F152 HydrophobicContact CE1-CG 4.19Å; G148-F152 WeakPolarHBondContact O-CB 3.44Å; G148-F152 PolarHBondContact O-N 2.85Å; V149-F152 PolarHBondContact O-N 3.45Å; F152-F154 VanDerWaalsContact C-N 3.32Å; F152-F154 PolarHBondContact O-N 3.37Å; F152-A155 PolarHBondContact O-N 3.12Å; F152-A155 VanDerWaalsContact O-N 3.09Å; F152-A156 HydrophobicContact CE1-CB 4.15Å; F152-A156 HydrophobicContact CZ-CB 4.41Å; F152-A156 WeakPolarHBondContact O-CB 3.28Å; F152-A156 PolarHBondContact O-N 3.37Å
153	D	91.9	Very high	90	Very high	10 Å²	10	17.1 Å²	17.1	5%	0.053	10%	0.096	C	C	.	.	H	α-helix	trans	-55	-49.6	179.3	-77.8	-38.7	0	0	0	110.8	S77 V149 A155 A156 D157	S77-D153 VanDerWaalsContact CB-CB 3.45Å; S77-D153 WeakPolarHBondContact OG-CB 3.4Å; V149-D153 PolarHBondContact O-N 3.03Å; D153-A155 VanDerWaalsContact C-N 3.32Å; D153-A155 PolarHBondContact O-N 3.48Å; D153-A156 PolarHBondContact O-N 3.44Å; D153-D157 WeakPolarHBondContact O-CB 3.46Å; D153-D157 PolarHBondContact O-N 3.27Å
154	F	89.5	Confident	89.8	Confident	25 Å²	25	15.1 Å²	15.1	11%	0.11	8%	0.081	C	C	.	.	H	α-helix	trans	-55.1	-48.4	177.1	173.1	-94.3	0	0	0	111.3	L80 L84 M112 V150 F152 F158	L80-F154 HydrophobicContact CB-CD2 3.93Å; L80-F154 HydrophobicContact CB-CE2 4.37Å; L84-F154 HydrophobicContact CB-CE2 3.93Å; L84-F154 HydrophobicContact CB-CZ 4.27Å; L84-F154 HydrophobicContact CD1-CE2 3.56Å; L84-F154 HydrophobicContact CD1-CZ 3.92Å; L84-F154 HydrophobicContact CG-CE2 4.34Å; M112-F154 HydrophobicContact SD-CD1 3.73Å; M112-F154 HydrophobicContact SD-CE1 3.94Å; V150-F154 WeakPolarHBondContact O-CB 3.36Å; V150-F154 PolarHBondContact O-N 3.25Å; F152-F154 VanDerWaalsContact C-N 3.32Å; F152-F154 PolarHBondContact O-N 3.37Å; F154-F158 AromaticContact CD2-CD2 3.79Å; F154-F158 HydrophobicContact CD2-CD2 3.79Å; F154-F158 AromaticContact CD2-CE2 3.31Å; F154-F158 HydrophobicContact CD2-CE2 3.31Å; F154-F158 AromaticContact CD2-CZ 3.82Å; F154-F158 HydrophobicContact CD2-CZ 3.82Å; F154-F158 HydrophobicContact CE1-CD1 4.39Å; F154-F158 HydrophobicContact CE1-CD2 4.5Å; F154-F158 HydrophobicContact CE1-CG 4.37Å; F154-F158 HydrophobicContact CE2-CD1 4.09Å; F154-F158 AromaticContact CE2-CD2 3.73Å; F154-F158 HydrophobicContact CE2-CD2 3.73Å; F154-F158 AromaticContact CE2-CE1 3.56Å; F154-F158 HydrophobicContact CE2-CE1 3.56Å; F154-F158 AromaticContact CE2-CE2 3.1Å; F154-F158 HydrophobicContact CE2-CE2 3.1Å; F154-F158 HydrophobicContact CE2-CG 4.17Å; F154-F158 AromaticContact CE2-CZ 3.08Å; F154-F158 HydrophobicContact CE2-CZ 3.08Å; F154-F158 HydrophobicContact CG-CD2 4.23Å; F154-F158 HydrophobicContact CG-CE2 4.18Å; F154-F158 AromaticContact CZ-CD1 3.79Å; F154-F158 HydrophobicContact CZ-CD1 3.79Å; F154-F158 HydrophobicContact CZ-CD2 4.09Å; F154-F158 AromaticContact CZ-CE1 3.55Å; F154-F158 HydrophobicContact CZ-CE1 3.55Å; F154-F158 AromaticContact CZ-CE2 3.81Å; F154-F158 HydrophobicContact CZ-CE2 3.81Å; F154-F158 HydrophobicContact CZ-CG 4.06Å; F154-F158 AromaticContact CZ-CZ 3.62Å; F154-F158 HydrophobicContact CZ-CZ 3.62Å; F154-F158 WeakPolarHBondContact O-CB 3.47Å; F154-F158 WeakPolarHBondContact O-CD2 3.47Å; F154-F158 WeakPolarHBondContact O-CG 3.47Å; F154-F158 PolarHBondContact O-N 3.46Å
155	A	92.4	Very high	89.3	Confident	0 Å²	0	14.1 Å²	14.1	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-68.4	-40.8	-178.8	0	0	0	0	0	112.3	L109 M112 M113 L151 F152 D153 D157 F158 I159	L109-A155 HydrophobicContact CD2-CB 4.45Å; M112-A155 HydrophobicContact CB-CB 3.85Å; M112-A155 HydrophobicContact CG-CB 3.74Å; M112-A155 HydrophobicContact SD-CB 3.91Å; M113-A155 HydrophobicContact CB-CB 4.39Å; M113-A155 HydrophobicContact CG-CB 3.47Å; M113-A155 VanDerWaalsContact CG-CB 3.47Å; L151-A155 VanDerWaalsContact O-CB 3.32Å; L151-A155 WeakPolarHBondContact O-CB 3.34Å; L151-A155 PolarHBondContact O-N 3.18Å; F152-A155 PolarHBondContact O-N 3.12Å; F152-A155 VanDerWaalsContact O-N 3.09Å; D153-A155 VanDerWaalsContact C-N 3.32Å; D153-A155 PolarHBondContact O-N 3.48Å; A155-D157 VanDerWaalsContact C-N 3.34Å; A155-D157 PolarHBondContact O-N 3.44Å; A155-F158 PolarHBondContact O-N 2.99Å; A155-I159 WeakPolarHBondContact O-CB 3.32Å; A155-I159 PolarHBondContact O-N 3.24Å; A155-I159 VanDerWaalsContact O-N 3.12Å
156	A	92.4	Very high	89.1	Confident	0 Å²	0	14.1 Å²	14.1	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-62.5	-40	178.2	0	0	0	0	0	111.5	R45 Y49 M113 F152 D153 I159	R45-A156 HydrophobicContact CG-CB 4.49Å; R45-A156 PolarHBondContact NE-O 3.05Å; R45-A156 PolarHBondContact NH2-O 2.86Å; Y49-A156 HydrophobicContact CD2-CB 3.91Å; Y49-A156 HydrophobicContact CE2-CB 4.34Å; M113-A156 HydrophobicContact CE-CB 3.79Å; M113-A156 HydrophobicContact SD-CB 4.31Å; F152-A156 HydrophobicContact CE1-CB 4.15Å; F152-A156 HydrophobicContact CZ-CB 4.41Å; F152-A156 WeakPolarHBondContact O-CB 3.28Å; F152-A156 PolarHBondContact O-N 3.37Å; D153-A156 PolarHBondContact O-N 3.44Å; A156-I159 WeakPolarHBondContact O-CG2 3.3Å
157	D	87.6	Confident	89	Confident	7 Å²	7	12 Å²	12	4%	0.037	7%	0.065	C	C	.	.	H	α-helix	trans	-75.2	-38.4	178.2	-82.1	-12.3	0	0	0	113.1	R45 D153 A155 I159 Q484	R45-D157 IonicContact NH2-OD1 3.64Å; R45-D157 PolarHBondContact NH2-OD1 3.35Å; R45-D157 VanDerWaalsContact NH2-OD1 3.15Å; D153-D157 WeakPolarHBondContact O-CB 3.46Å; D153-D157 PolarHBondContact O-N 3.27Å; A155-D157 VanDerWaalsContact C-N 3.34Å; A155-D157 PolarHBondContact O-N 3.44Å; D157-I159 VanDerWaalsContact C-N 3.34Å; D157-I159 PolarHBondContact O-N 2.99Å; D157-Q484 PolarHBondContact OD2-NE2 3.18Å
158	F	85.7	Confident	88.6	Confident	5 Å²	5	7.9 Å²	7.9	2%	0.022	4%	0.044	C	C	.	.	H	α-helix	trans	-71.8	-31.3	-176.8	-87.1	-122	0	0	0	112.8	G81 L84 Q85 V88 L109 F154 A155 D160 G161 P162	G81-F158 VanDerWaalsContact CA-CE2 3.41Å; G81-F158 WeakPolarHBondContact O-CZ 3.43Å; L84-F158 HydrophobicContact CB-CE1 3.79Å; L84-F158 HydrophobicContact CB-CZ 3.62Å; Q85-F158 HydrophobicContact CB-CE1 3.94Å; Q85-F158 HydrophobicContact CB-CE2 4.44Å; Q85-F158 HydrophobicContact CB-CZ 3.8Å; V88-F158 HydrophobicContact CB-CD1 3.81Å; V88-F158 HydrophobicContact CB-CE1 3.91Å; V88-F158 HydrophobicContact CG1-CD1 4.03Å; V88-F158 HydrophobicContact CG2-CD1 3.86Å; V88-F158 HydrophobicContact CG2-CE1 3.68Å; L109-F158 HydrophobicContact CD1-CB 4.09Å; L109-F158 HydrophobicContact CD2-CB 3.97Å; F154-F158 AromaticContact CD2-CD2 3.79Å; F154-F158 HydrophobicContact CD2-CD2 3.79Å; F154-F158 AromaticContact CD2-CE2 3.31Å; F154-F158 HydrophobicContact CD2-CE2 3.31Å; F154-F158 AromaticContact CD2-CZ 3.82Å; F154-F158 HydrophobicContact CD2-CZ 3.82Å; F154-F158 HydrophobicContact CE1-CD1 4.39Å; F154-F158 HydrophobicContact CE1-CD2 4.5Å; F154-F158 HydrophobicContact CE1-CG 4.37Å; F154-F158 HydrophobicContact CE2-CD1 4.09Å; F154-F158 AromaticContact CE2-CD2 3.73Å; F154-F158 HydrophobicContact CE2-CD2 3.73Å; F154-F158 AromaticContact CE2-CE1 3.56Å; F154-F158 HydrophobicContact CE2-CE1 3.56Å; F154-F158 AromaticContact CE2-CE2 3.1Å; F154-F158 HydrophobicContact CE2-CE2 3.1Å; F154-F158 HydrophobicContact CE2-CG 4.17Å; F154-F158 AromaticContact CE2-CZ 3.08Å; F154-F158 HydrophobicContact CE2-CZ 3.08Å; F154-F158 HydrophobicContact CG-CD2 4.23Å; F154-F158 HydrophobicContact CG-CE2 4.18Å; F154-F158 AromaticContact CZ-CD1 3.79Å; F154-F158 HydrophobicContact CZ-CD1 3.79Å; F154-F158 HydrophobicContact CZ-CD2 4.09Å; F154-F158 AromaticContact CZ-CE1 3.55Å; F154-F158 HydrophobicContact CZ-CE1 3.55Å; F154-F158 AromaticContact CZ-CE2 3.81Å; F154-F158 HydrophobicContact CZ-CE2 3.81Å; F154-F158 HydrophobicContact CZ-CG 4.06Å; F154-F158 AromaticContact CZ-CZ 3.62Å; F154-F158 HydrophobicContact CZ-CZ 3.62Å; F154-F158 WeakPolarHBondContact O-CB 3.47Å; F154-F158 WeakPolarHBondContact O-CD2 3.47Å; F154-F158 WeakPolarHBondContact O-CG 3.47Å; F154-F158 PolarHBondContact O-N 3.46Å; A155-F158 PolarHBondContact O-N 2.99Å; F158-D160 VanDerWaalsContact C-N 3.27Å; F158-D160 PolarHBondContact O-N 3.28Å; F158-G161 PolarHBondContact O-N 3.03Å; F158-P162 WeakPolarHBondContact O-CD 3.29Å
159	I	88.9	Confident	88	Confident	0 Å²	0	10.9 Å²	10.9	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-70.3	-25	-172.4	-154	179.9	0	0	0	113.5	R45 I106 L109 M113 A155 A156 D157 G161 P162 I163 F230	R45-I159 HydrophobicContact CG-CG2 4.02Å; I106-I159 HydrophobicContact CG2-CD1 3.91Å; I106-I159 HydrophobicContact CG2-CG1 4.26Å; L109-I159 HydrophobicContact CB-CB 4.07Å; L109-I159 HydrophobicContact CB-CD1 3.99Å; L109-I159 HydrophobicContact CB-CG1 3.88Å; L109-I159 HydrophobicContact CD1-CB 4.07Å; L109-I159 HydrophobicContact CD1-CG1 4.07Å; M113-I159 HydrophobicContact SD-CG2 4.35Å; A155-I159 WeakPolarHBondContact O-CB 3.32Å; A155-I159 PolarHBondContact O-N 3.24Å; A155-I159 VanDerWaalsContact O-N 3.12Å; A156-I159 WeakPolarHBondContact O-CG2 3.3Å; D157-I159 VanDerWaalsContact C-N 3.34Å; D157-I159 PolarHBondContact O-N 2.99Å; I159-G161 VanDerWaalsContact C-N 3.3Å; I159-G161 PolarHBondContact O-N 3.05Å; I159-P162 WeakPolarHBondContact O-CD 3.46Å; I159-I163 HydrophobicContact CB-CD1 4.38Å; I159-I163 HydrophobicContact CD1-CD1 4.04Å; I159-I163 HydrophobicContact CG1-CD1 3.78Å; I159-I163 HydrophobicContact CG1-CG1 4.16Å; I159-I163 HydrophobicContact CG2-CD1 4.07Å; I159-I163 WeakPolarHBondContact O-CB 3.37Å; I159-I163 WeakPolarHBondContact O-CD1 3.3Å; I159-I163 VanDerWaalsContact O-CG1 3.26Å; I159-I163 WeakPolarHBondContact O-CG1 3.2Å; I159-I163 PolarHBondContact O-N 2.87Å; I159-F230 HydrophobicContact CD1-CD1 4.4Å; I159-F230 HydrophobicContact CD1-CE1 3.14Å; I159-F230 HydrophobicContact CD1-CE2 4.47Å; I159-F230 HydrophobicContact CD1-CZ 3.2Å
160	D	86.9	Confident	87.6	Confident	8 Å²	8	11.2 Å²	11.2	4%	0.043	6%	0.062	C	C	.	.	H	α-helix	trans	-56.4	-43.8	177.7	179.2	60.7	0	0	0	112	M42 F158 I163 K164	M42-D160 VanDerWaalsContact CE-OD1 3.27Å; M42-D160 WeakPolarHBondContact CE-OD1 3.45Å; F158-D160 VanDerWaalsContact C-N 3.27Å; F158-D160 PolarHBondContact O-N 3.28Å; D160-I163 PolarHBondContact O-N 2.9Å; D160-K164 WeakPolarHBondContact O-CB 3.27Å; D160-K164 WeakPolarHBondContact O-CG 3.47Å; D160-K164 PolarHBondContact O-N 2.93Å; D160-K164 WeakPolarHBondContact OD1-CE 3.46Å; D160-K164 IonicContact OD1-NZ 2.72Å; D160-K164 PolarHBondContact OD1-NZ 3.25Å; D160-K164 WeakPolarHBondContact OD2-CE 3.37Å; D160-K164 IonicContact OD2-NZ 3.31Å; D160-K164 PolarHBondContact OD2-NZ 3.04Å
161	G	82.1	Confident	87.2	Confident	10 Å²	10	10.3 Å²	10.3	10%	0.103	6%	0.057	C	C	.	.	H	α-helix	trans	-60	-60	179.6	0	0	0	0	0	113.1	F158 I159 I163 K164 A165	F158-G161 PolarHBondContact O-N 3.03Å; I159-G161 VanDerWaalsContact C-N 3.3Å; I159-G161 PolarHBondContact O-N 3.05Å; G161-I163 VanDerWaalsContact C-N 3.32Å; G161-I163 PolarHBondContact O-N 3.04Å; G161-K164 PolarHBondContact O-N 3.21Å; G161-A165 WeakPolarHBondContact O-CB 3.37Å; G161-A165 PolarHBondContact O-N 2.77Å
162	P	84.1	Confident	86.7	Confident	9 Å²	9	8.2 Å²	8.2	6%	0.058	5%	0.046	C	C	.	.	H	α-helix	trans	-57.6	-36.5	175.6	-27.9	36.9	0	0	0	114.3	I106 L109 F158 I159 Y166	I106-P162 HydrophobicContact CD1-CB 4.47Å; I106-P162 HydrophobicContact CG1-CB 3.88Å; L109-P162 HydrophobicContact CD1-CG 4.32Å; F158-P162 WeakPolarHBondContact O-CD 3.29Å; I159-P162 WeakPolarHBondContact O-CD 3.46Å; P162-Y166 WeakPolarHBondContact O-CB 3.37Å; P162-Y166 PolarHBondContact O-N 3.39Å
163	I	88.6	Confident	85.9	Confident	0 Å²	0	9.6 Å²	9.6	0%	0	5%	0.052	C	C	.	.	H	α-helix	trans	-64	-47.2	176	-72.1	166.5	0	0	0	110.8	A41 M42 I106 I159 D160 G161 Y166 L167	A41-I163 HydrophobicContact CB-CD1 3.69Å; A41-I163 HydrophobicContact CB-CG1 4.37Å; M42-I163 HydrophobicContact CG-CG2 4.24Å; M42-I163 HydrophobicContact SD-CD1 4.42Å; M42-I163 HydrophobicContact SD-CG2 4.01Å; I106-I163 HydrophobicContact CD1-CG1 4.01Å; I106-I163 HydrophobicContact CG1-CG1 4.22Å; I106-I163 HydrophobicContact CG2-CG1 4.27Å; I159-I163 HydrophobicContact CB-CD1 4.38Å; I159-I163 HydrophobicContact CD1-CD1 4.04Å; I159-I163 HydrophobicContact CG1-CD1 3.78Å; I159-I163 HydrophobicContact CG1-CG1 4.16Å; I159-I163 HydrophobicContact CG2-CD1 4.07Å; I159-I163 WeakPolarHBondContact O-CB 3.37Å; I159-I163 WeakPolarHBondContact O-CD1 3.3Å; I159-I163 VanDerWaalsContact O-CG1 3.26Å; I159-I163 WeakPolarHBondContact O-CG1 3.2Å; I159-I163 PolarHBondContact O-N 2.87Å; D160-I163 PolarHBondContact O-N 2.9Å; G161-I163 VanDerWaalsContact C-N 3.32Å; G161-I163 PolarHBondContact O-N 3.04Å; I163-Y166 WeakPolarHBondContact O-CB 3.38Å; I163-Y166 PolarHBondContact O-N 3.49Å; I163-L167 PolarHBondContact O-N 3Å
164	K	86.4	Confident	85.4	Confident	3 Å²	3	14 Å²	14	1%	0.013	7%	0.073	C	C	.	.	H	α-helix	trans	-67	-42.8	177.6	-73.6	174.2	178.2	158.4	0	112.2	D160 G161 Y166 L167 F168 F443	D160-K164 WeakPolarHBondContact O-CB 3.27Å; D160-K164 WeakPolarHBondContact O-CG 3.47Å; D160-K164 PolarHBondContact O-N 2.93Å; D160-K164 WeakPolarHBondContact OD1-CE 3.46Å; D160-K164 IonicContact OD1-NZ 2.72Å; D160-K164 PolarHBondContact OD1-NZ 3.25Å; D160-K164 WeakPolarHBondContact OD2-CE 3.37Å; D160-K164 IonicContact OD2-NZ 3.31Å; D160-K164 PolarHBondContact OD2-NZ 3.04Å; G161-K164 PolarHBondContact O-N 3.21Å; K164-Y166 VanDerWaalsContact C-N 3.26Å; K164-Y166 PolarHBondContact O-N 3.36Å; K164-L167 WeakPolarHBondContact O-CB 3.3Å; K164-L167 PolarHBondContact O-N 3.21Å; K164-F168 WeakPolarHBondContact O-CG 3.32Å; K164-F168 PolarHBondContact O-N 3.25Å; K164-F443 HydrophobicContact CD-CD1 3.95Å; K164-F443 HydrophobicContact CD-CD2 4.5Å; K164-F443 HydrophobicContact CD-CE1 3.67Å; K164-F443 HydrophobicContact CD-CE2 4.26Å; K164-F443 HydrophobicContact CD-CG 4.37Å; K164-F443 HydrophobicContact CD-CZ 3.86Å
165	A	82.2	Confident	85.2	Confident	6 Å²	6	12.9 Å²	12.9	5%	0.05	7%	0.068	C	C	.	.	H	α-helix	trans	-60.5	-39.3	174.8	0	0	0	0	0	111.3	G161 F168 D169	G161-A165 WeakPolarHBondContact O-CB 3.37Å; G161-A165 PolarHBondContact O-N 2.77Å; A165-F168 PolarHBondContact O-N 3.03Å; A165-D169 WeakPolarHBondContact O-CB 3.47Å; A165-D169 PolarHBondContact O-N 3.37Å
166	Y	85.8	Confident	84.9	Confident	0 Å²	0	13.9 Å²	13.9	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-63	-45.7	175.7	-179.3	-157.7	0	0	0	112	H38 R102 R103 I106 P162 I163 K164 F168 D169 V170 H233 I237 E239	H38-Y166 AromaticContact CE1-CD1 3.25Å; H38-Y166 WeakPolarHBondContact CE1-CD1 3.17Å; H38-Y166 AromaticContact CE1-CE1 3.45Å; H38-Y166 VanDerWaalsContact CE1-CE1 3.45Å; H38-Y166 WeakPolarHBondContact CE1-CE1 3.31Å; H38-Y166 AromaticContact CE1-CG 3.62Å; H38-Y166 AromaticContact CE1-CZ 3.96Å; H38-Y166 AromaticContact ND1-CE1 3.97Å; H38-Y166 AromaticContact NE2-CD1 3.85Å; R102-Y166 HydrophobicContact CB-CD2 4.33Å; R102-Y166 HydrophobicContact CB-CG 4.06Å; R102-Y166 HydrophobicContact CG-CG 4.44Å; R103-Y166 HydrophobicContact CG-CE1 4.15Å; R103-Y166 PolarHBondContact NE-OH 3.27Å; R103-Y166 PolarHBondContact NH2-OH 2.71Å; R103-Y166 VanDerWaalsContact NH2-OH 3.16Å; I106-Y166 HydrophobicContact CD1-CD1 3.65Å; I106-Y166 HydrophobicContact CD1-CE1 4.44Å; I106-Y166 HydrophobicContact CD1-CG 4.32Å; P162-Y166 WeakPolarHBondContact O-CB 3.37Å; P162-Y166 PolarHBondContact O-N 3.39Å; I163-Y166 WeakPolarHBondContact O-CB 3.38Å; I163-Y166 PolarHBondContact O-N 3.49Å; K164-Y166 VanDerWaalsContact C-N 3.26Å; K164-Y166 PolarHBondContact O-N 3.36Å; Y166-F168 VanDerWaalsContact C-N 3.27Å; Y166-F168 PolarHBondContact O-N 3.44Å; Y166-D169 PolarHBondContact O-N 3Å; Y166-V170 HydrophobicContact CD2-CG1 3.83Å; Y166-V170 HydrophobicContact CD2-CG2 4.32Å; Y166-V170 HydrophobicContact CE2-CG1 3.53Å; Y166-V170 HydrophobicContact CE2-CG2 4.26Å; Y166-V170 VanDerWaalsContact O-CG2 3.26Å; Y166-V170 WeakPolarHBondContact O-CG2 3.43Å; Y166-V170 PolarHBondContact O-N 3.46Å; Y166-H233 AromaticContact CD1-CE1 3.87Å; Y166-H233 AromaticContact CD1-NE2 3.54Å; Y166-H233 AromaticContact CE1-NE2 3.63Å; Y166-I237 PolarHBondContact OH-O 3.31Å; Y166-E239 HydrophobicContact CE2-CB 3.93Å; Y166-E239 HydrophobicContact CE2-CG 4.14Å
167	L	87.8	Confident	84.5	Confident	0 Å²	0	16.8 Å²	16.8	0%	0	9%	0.086	C	C	.	.	H	α-helix	trans	-54.8	-44.5	172.6	-179.9	71.9	0	0	0	111.5	L35 I163 K164 D169 V170 C171 L180	L35-L167 HydrophobicContact CD2-CD1 4.12Å; I163-L167 PolarHBondContact O-N 3Å; K164-L167 WeakPolarHBondContact O-CB 3.3Å; K164-L167 PolarHBondContact O-N 3.21Å; L167-D169 VanDerWaalsContact C-N 3.32Å; L167-D169 PolarHBondContact O-N 3.41Å; L167-V170 PolarHBondContact O-N 3.42Å; L167-C171 HydrophobicContact CD1-CB 4.48Å; L167-C171 VanDerWaalsContact O-CB 3.28Å; L167-C171 WeakPolarHBondContact O-CB 3.37Å; L167-C171 PolarHBondContact O-N 2.96Å; L167-L180 HydrophobicContact CD2-CB 4.49Å
168	F	83.9	Confident	84.5	Confident	15 Å²	15	19.4 Å²	19.4	7%	0.066	10%	0.097	C	C	.	.	H	α-helix	trans	-70.5	-27.2	-179.1	-68.5	-3.1	0	0	0	113.9	K164 A165 Y166 K176 F443	K164-F168 WeakPolarHBondContact O-CG 3.32Å; K164-F168 PolarHBondContact O-N 3.25Å; A165-F168 PolarHBondContact O-N 3.03Å; Y166-F168 VanDerWaalsContact C-N 3.27Å; Y166-F168 PolarHBondContact O-N 3.44Å; F168-K176 HydrophobicContact CB-CD 4.46Å; F168-K176 HydrophobicContact CD1-CB 4.08Å; F168-K176 HydrophobicContact CD1-CD 4.03Å; F168-K176 HydrophobicContact CD1-CG 3.94Å; F168-K176 HydrophobicContact CE1-CB 4.16Å; F168-K176 HydrophobicContact CG-CD 4.4Å; F168-K176 WeakPolarHBondContact O-CE 3.4Å; F168-K176 PolarHBondContact O-NZ 3.08Å; F168-F443 HydrophobicContact CZ-CB 4.19Å
169	D	80.8	Confident	84.7	Confident	64 Å²	64	19.2 Å²	19.2	34%	0.342	10%	0.096	S	C	.	.	H	α-helix	trans	-76.5	-30.1	177.1	-72.1	-23.3	0	0	0	111.9	R101 R102 A165 Y166 L167	R101-D169 IonicContact CZ-OD2 3.49Å; R101-D169 IonicContact NE-OD2 3.73Å; R101-D169 VanDerWaalsContact NH2-CG 3.3Å; R101-D169 IonicContact NH2-OD1 2.76Å; R101-D169 PolarHBondContact NH2-OD1 2.85Å; R101-D169 IonicContact NH2-OD2 3.78Å; R101-D169 PolarHBondContact NH2-OD2 3.22Å; R102-D169 IonicContact CZ-OD2 3.98Å; R102-D169 IonicContact NE-OD2 3.89Å; R102-D169 PolarHBondContact NE-OD2 3.36Å; R102-D169 IonicContact NH2-OD2 3.04Å; R102-D169 PolarHBondContact NH2-OD2 3Å; A165-D169 WeakPolarHBondContact O-CB 3.47Å; A165-D169 PolarHBondContact O-N 3.37Å; Y166-D169 PolarHBondContact O-N 3Å; L167-D169 VanDerWaalsContact C-N 3.32Å; L167-D169 PolarHBondContact O-N 3.41Å
170	V	83.2	Confident	84.7	Confident	8 Å²	8	19.2 Å²	19.2	5%	0.048	10%	0.096	C	C	.	.	H	α-helix	trans	-108	-13.7	-171.6	-64.1	0	0	0	0	117	R30 Y166 L167 I237	R30-V170 PolarHBondContact NE-O 2.87Å; R30-V170 PolarHBondContact NH2-O 3.37Å; R30-V170 VanDerWaalsContact NH2-O 3.14Å; Y166-V170 HydrophobicContact CD2-CG1 3.83Å; Y166-V170 HydrophobicContact CD2-CG2 4.32Å; Y166-V170 HydrophobicContact CE2-CG1 3.53Å; Y166-V170 HydrophobicContact CE2-CG2 4.26Å; Y166-V170 VanDerWaalsContact O-CG2 3.26Å; Y166-V170 WeakPolarHBondContact O-CG2 3.43Å; Y166-V170 PolarHBondContact O-N 3.46Å; L167-V170 PolarHBondContact O-N 3.42Å; V170-I237 HydrophobicContact CB-CG2 3.87Å; V170-I237 HydrophobicContact CG1-CG2 4.23Å; V170-I237 HydrophobicContact CG2-CB 4.37Å; V170-I237 HydrophobicContact CG2-CD1 4.01Å; V170-I237 HydrophobicContact CG2-CG2 3.95Å
171	C	83.6	Confident	84.9	Confident	0 Å²	0	19.8 Å²	19.8	0%	0	10%	0.098	C	C	.	.	S	Bend	trans	-107.4	146.3	-173.6	-71	0	0	0	0	112.7	P27 L35 L167 D175 K176	P27-C171 WeakPolarHBondContact CG-O 3.28Å; L35-C171 VanDerWaalsContact CD2-SG 3.55Å; L167-C171 HydrophobicContact CD1-CB 4.48Å; L167-C171 VanDerWaalsContact O-CB 3.28Å; L167-C171 WeakPolarHBondContact O-CB 3.37Å; L167-C171 PolarHBondContact O-N 2.96Å; C171-D175 HydrophobicContact CB-CB 3.9Å; C171-K176 HydrophobicContact CB-CG 4.06Å; C171-K176 WeakPolarHBondContact O-CE 3.39Å
172	S	82.3	Confident	85.4	Confident	3 Å²	3	21.9 Å²	21.9	2%	0.021	10%	0.103	C	C	.	.			trans	-60.4	160.5	167.3	72.2	0	0	0	0	110.6	P27 Q174 D175 K176	P27-S172 WeakPolarHBondContact O-CB 3.49Å; S172-Q174 VanDerWaalsContact C-N 3.3Å; S172-Q174 PolarHBondContact O-N 3.35Å; S172-D175 CarbonylContact O-C 3.44Å; S172-D175 PolarHBondContact O-N 3.46Å; S172-D175 WeakPolarHBondContact OG-CB 3.27Å; S172-D175 PolarHBondContact OG-N 2.97Å; S172-D175 PolarHBondContact OG-OD2 3.49Å; S172-K176 WeakPolarHBondContact O-CG 3.38Å; S172-K176 PolarHBondContact O-N 2.9Å
173	H	78.2	Confident	85.8	Confident	29 Å²	29	21.5 Å²	21.5	13%	0.134	10%	0.101	C	C	.	.	H	α-helix	trans	-52	-48.3	-178.3	-171.2	-79.2	0	0	0	112.4	E26 D175 K176 E177 E448 R451	E26-H173 WeakPolarHBondContact OE1-CB 3.37Å; E26-H173 PolarHBondContact OE1-N 3.26Å; H173-D175 PolarHBondContact O-N 2.91Å; H173-K176 WeakPolarHBondContact O-CB 3.32Å; H173-K176 PolarHBondContact O-N 3.3Å; H173-E177 IonicContact CE1-OE1 2.93Å; H173-E177 IonicContact ND1-OE1 2.93Å; H173-E448 IonicContact CE1-OE2 3.15Å; H173-E448 PolarHBondContact CE1-OE2 3Å; H173-E448 IonicContact NE2-OE2 3.01Å; H173-E448 PolarHBondContact NE2-OE2 3.26Å; H173-R451 WeakPolarHBondContact NE2-CD 3.43Å
174	Q	80.1	Confident	85.9	Confident	102 Å²	102	21.6 Å²	21.6	48%	0.477	10%	0.102	S	C	.	.	H	α-helix	trans	-64.2	-27.6	178.5	-65.4	-175.8	-16.5	0	0	113.3	K29 S172 K178	K29-Q174 VanDerWaalsContact NZ-OE1 3.15Å; S172-Q174 VanDerWaalsContact C-N 3.3Å; S172-Q174 PolarHBondContact O-N 3.35Å; Q174-K178 WeakPolarHBondContact O-CG 3.24Å
175	D	86.3	Confident	86.2	Confident	2 Å²	2	23.2 Å²	23.2	1%	0.011	11%	0.11	C	C	.	.	H	α-helix	trans	-88.1	-18.3	-179.1	-64.6	-27.7	0	0	0	112.5	K29 R30 L35 C171 S172 H173 K178 G179	K29-D175 VanDerWaalsContact CA-OD2 3.27Å; K29-D175 WeakPolarHBondContact CA-OD2 3.48Å; R30-D175 PolarHBondContact N-OD2 3.3Å; L35-D175 HydrophobicContact CD1-CB 4.33Å; C171-D175 HydrophobicContact CB-CB 3.9Å; S172-D175 CarbonylContact O-C 3.44Å; S172-D175 PolarHBondContact O-N 3.46Å; S172-D175 WeakPolarHBondContact OG-CB 3.27Å; S172-D175 PolarHBondContact OG-N 2.97Å; S172-D175 PolarHBondContact OG-OD2 3.49Å; H173-D175 PolarHBondContact O-N 2.91Å; D175-K178 IonicContact OD1-NZ 3.5Å; D175-K178 PolarHBondContact OD1-NZ 3.34Å; D175-G179 PolarHBondContact O-N 3.43Å
176	K	86.3	Confident	86.8	Confident	21 Å²	21	24.6 Å²	24.6	9%	0.091	12%	0.115	C	C	.	.	H	α-helix	trans	-63.4	-50.7	171.7	-68.4	175.3	-169	-173.7	0	110.9	F168 C171 S172 H173 K178 G179 L180 T447	F168-K176 HydrophobicContact CB-CD 4.46Å; F168-K176 HydrophobicContact CD1-CB 4.08Å; F168-K176 HydrophobicContact CD1-CD 4.03Å; F168-K176 HydrophobicContact CD1-CG 3.94Å; F168-K176 HydrophobicContact CE1-CB 4.16Å; F168-K176 HydrophobicContact CG-CD 4.4Å; F168-K176 WeakPolarHBondContact O-CE 3.4Å; F168-K176 PolarHBondContact O-NZ 3.08Å; C171-K176 HydrophobicContact CB-CG 4.06Å; C171-K176 WeakPolarHBondContact O-CE 3.39Å; S172-K176 WeakPolarHBondContact O-CG 3.38Å; S172-K176 PolarHBondContact O-N 2.9Å; H173-K176 WeakPolarHBondContact O-CB 3.32Å; H173-K176 PolarHBondContact O-N 3.3Å; K176-K178 PolarHBondContact O-N 3.34Å; K176-G179 PolarHBondContact O-N 2.72Å; K176-L180 WeakPolarHBondContact O-CB 3.31Å; K176-L180 PolarHBondContact O-N 2.89Å; K176-T447 HydrophobicContact CB-CG2 4.47Å; K176-T447 HydrophobicContact CD-CG2 3.91Å
177	E	84.8	Confident	87.2	Confident	61 Å²	61	24.7 Å²	24.7	29%	0.285	12%	0.116	S	C	.	.	H	α-helix	trans	-59.2	-49.3	176.9	-67.6	171	-163.7	0	0	111.1	H173 G179 L180 H181	H173-E177 IonicContact CE1-OE1 2.93Å; H173-E177 IonicContact ND1-OE1 2.93Å; E177-G179 VanDerWaalsContact C-N 3.34Å; E177-G179 PolarHBondContact O-N 3.21Å; E177-L180 PolarHBondContact O-N 3.35Å; E177-H181 PolarHBondContact O-CD2 2.86Å; E177-H181 PolarHBondContact O-N 3.3Å
178	K	87.2	Confident	87.4	Confident	62 Å²	62	24.9 Å²	24.9	27%	0.27	12%	0.118	S	C	.	.	H	α-helix	trans	-58.6	-45.8	176.3	-68.7	175.6	-159.1	154.7	0	111.9	L35 Q174 D175 K176 L180 H181 Y182	L35-K178 HydrophobicContact CD1-CB 4.09Å; Q174-K178 WeakPolarHBondContact O-CG 3.24Å; D175-K178 IonicContact OD1-NZ 3.5Å; D175-K178 PolarHBondContact OD1-NZ 3.34Å; K176-K178 PolarHBondContact O-N 3.34Å; K178-L180 VanDerWaalsContact C-N 3.29Å; K178-L180 PolarHBondContact O-N 3.39Å; K178-H181 PolarHBondContact O-N 3.45Å; K178-Y182 HydrophobicContact CB-CE2 4.48Å; K178-Y182 WeakPolarHBondContact O-CD2 3.38Å; K178-Y182 PolarHBondContact O-N 3.01Å
179	G	89.6	Confident	87.9	Confident	0 Å²	0	28.9 Å²	28.9	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-60	-41.2	178.5	0	0	0	0	0	111.6	D175 K176 E177 Y182 H183	D175-G179 PolarHBondContact O-N 3.43Å; K176-G179 PolarHBondContact O-N 2.72Å; E177-G179 VanDerWaalsContact C-N 3.34Å; E177-G179 PolarHBondContact O-N 3.21Å; G179-Y182 PolarHBondContact O-N 3.48Å; G179-H183 PolarHBondContact O-CD2 2.88Å; G179-H183 PolarHBondContact O-N 3.41Å
180	L	89.1	Confident	88.5	Confident	1 Å²	1	25.9 Å²	25.9	1%	0.005	12%	0.119	C	C	.	.	H	α-helix	trans	-68	-37.6	177.7	-169.3	69.4	0	0	0	112.6	L167 K176 E177 K178 H183 A184 T440 F443 N444	L167-L180 HydrophobicContact CD2-CB 4.49Å; K176-L180 WeakPolarHBondContact O-CB 3.31Å; K176-L180 PolarHBondContact O-N 2.89Å; E177-L180 PolarHBondContact O-N 3.35Å; K178-L180 VanDerWaalsContact C-N 3.29Å; K178-L180 PolarHBondContact O-N 3.39Å; L180-H183 WeakPolarHBondContact O-CB 3.44Å; L180-H183 PolarHBondContact O-N 3.3Å; L180-A184 PolarHBondContact O-N 3.05Å; L180-T440 WeakPolarHBondContact CD2-O 3.49Å; L180-T440 HydrophobicContact CG-CG2 4.35Å; L180-F443 HydrophobicContact CD1-CB 4.31Å; L180-F443 HydrophobicContact CD2-CB 3.6Å; L180-N444 WeakPolarHBondContact CD2-OD1 3.29Å
181	H	90	Very high	89	Confident	20 Å²	20	25.5 Å²	25.5	9%	0.093	12%	0.117	C	C	.	.	H	α-helix	trans	-62.9	-41.5	171.1	-70.8	-60	0	0	0	112.1	E177 K178 A184 L185 Q388	E177-H181 PolarHBondContact O-CD2 2.86Å; E177-H181 PolarHBondContact O-N 3.3Å; K178-H181 PolarHBondContact O-N 3.45Å; H181-A184 PolarHBondContact O-N 3.13Å; H181-L185 WeakPolarHBondContact O-CB 3.23Å; H181-L185 PolarHBondContact O-N 3.49Å; H181-Q388 PolarHBondContact ND1-OE1 3.45Å
182	Y	92.2	Very high	89.4	Confident	53 Å²	53	25.9 Å²	25.9	21%	0.208	12%	0.12	C	C	.	.	H	α-helix	trans	-65.2	-39.4	173.1	-71.3	-61.4	0	0	0	111.8	T32 L35 I36 S39 K178 G179 A184 L185 F186	T32-Y182 HydrophobicContact CG2-CE2 3.82Å; T32-Y182 WeakPolarHBondContact CG2-OH 3.46Å; L35-Y182 HydrophobicContact CB-CD2 4.01Å; L35-Y182 HydrophobicContact CB-CE2 4.4Å; L35-Y182 HydrophobicContact CD1-CE2 4.48Å; I36-Y182 HydrophobicContact CD1-CE1 4.4Å; I36-Y182 HydrophobicContact CG1-CD1 4.08Å; I36-Y182 HydrophobicContact CG1-CE1 4.08Å; I36-Y182 HydrophobicContact CG1-CG 4.42Å; S39-Y182 WeakPolarHBondContact OG-CB 3.47Å; K178-Y182 HydrophobicContact CB-CE2 4.48Å; K178-Y182 WeakPolarHBondContact O-CD2 3.38Å; K178-Y182 PolarHBondContact O-N 3.01Å; G179-Y182 PolarHBondContact O-N 3.48Å; Y182-A184 VanDerWaalsContact C-N 3.35Å; Y182-A184 PolarHBondContact O-N 3.46Å; Y182-L185 HydrophobicContact CD1-CD2 4.06Å; Y182-L185 WeakPolarHBondContact O-CB 3.25Å; Y182-L185 PolarHBondContact O-N 3.03Å; Y182-F186 HydrophobicContact CD1-CE2 4.41Å; Y182-F186 WeakPolarHBondContact O-CB 3.12Å; Y182-F186 VanDerWaalsContact O-CD2 3.26Å; Y182-F186 WeakPolarHBondContact O-CD2 3.24Å; Y182-F186 PolarHBondContact O-N 2.86Å
183	H	93.3	Very high	89.8	Confident	2 Å²	2	28.5 Å²	28.5	1%	0.009	13%	0.134	C	C	.	.	H	α-helix	trans	-55	-50.8	173.2	-76.5	-162	0	0	0	110.8	H38 S39 M42 G179 L180 F186 T187	H38-H183 AromaticContact CD2-CE1 3.93Å; H38-H183 AromaticContact CD2-NE2 3.35Å; H38-H183 PolarHBondContact CD2-NE2 3.32Å; S39-H183 PolarHBondContact OG-CD2 3.29Å; M42-H183 HydrophobicContact CE-CB 4.39Å; M42-H183 HydrophobicContact CG-CB 3.87Å; G179-H183 PolarHBondContact O-CD2 2.88Å; G179-H183 PolarHBondContact O-N 3.41Å; L180-H183 WeakPolarHBondContact O-CB 3.44Å; L180-H183 PolarHBondContact O-N 3.3Å; H183-F186 PolarHBondContact O-N 2.83Å; H183-T187 WeakPolarHBondContact O-CB 3.32Å; H183-T187 PolarHBondContact O-N 2.79Å; H183-T187 PolarHBondContact O-OG1 3.29Å
184	A	90.8	Very high	90.4	Very high	2 Å²	2	27.1 Å²	27.1	2%	0.017	13%	0.127	C	C	.	.	H	α-helix	trans	-67	-38.8	-179	0	0	0	0	0	112.9	L180 H181 Y182 T187 G188 S385 T440	L180-A184 PolarHBondContact O-N 3.05Å; H181-A184 PolarHBondContact O-N 3.13Å; Y182-A184 VanDerWaalsContact C-N 3.35Å; Y182-A184 PolarHBondContact O-N 3.46Å; A184-T187 PolarHBondContact O-N 2.94Å; A184-G188 PolarHBondContact O-N 3.27Å; A184-S385 VanDerWaalsContact CB-OG 3.29Å; A184-S385 WeakPolarHBondContact CB-OG 3.34Å; A184-T440 HydrophobicContact CB-CG2 3.38Å
185	L	93.3	Very high	90.7	Very high	36 Å²	36	24.4 Å²	24.4	19%	0.188	11%	0.113	C	C	.	.	H	α-helix	trans	-55.8	-54.7	172.4	177	71.8	0	0	0	111.1	H181 Y182 T187 G188 F189 S382	H181-L185 WeakPolarHBondContact O-CB 3.23Å; H181-L185 PolarHBondContact O-N 3.49Å; Y182-L185 HydrophobicContact CD1-CD2 4.06Å; Y182-L185 WeakPolarHBondContact O-CB 3.25Å; Y182-L185 PolarHBondContact O-N 3.03Å; L185-T187 VanDerWaalsContact C-N 3.35Å; L185-T187 PolarHBondContact O-N 3.14Å; L185-G188 PolarHBondContact O-N 2.87Å; L185-F189 PolarHBondContact O-N 3.36Å; L185-S382 WeakPolarHBondContact CD1-O 3.39Å; L185-S382 WeakPolarHBondContact CD1-OG 3.48Å; L185-S382 WeakPolarHBondContact O-CB 3.18Å; L185-S382 PolarHBondContact O-OG 3.3Å
186	F	94.6	Very high	90.7	Very high	35 Å²	35	27.6 Å²	27.6	15%	0.154	13%	0.13	C	C	.	.	H	α-helix	trans	-71.3	-28.9	-177.1	-84.6	-73.6	0	0	0	113	I36 M40 F43 Y182 H183 G190	I36-F186 HydrophobicContact CB-CE2 4.38Å; I36-F186 HydrophobicContact CG1-CE2 4.27Å; I36-F186 HydrophobicContact CG2-CE2 3.8Å; I36-F186 HydrophobicContact CG2-CZ 3.66Å; M40-F186 HydrophobicContact SD-CD1 4.08Å; M40-F186 HydrophobicContact SD-CE1 3.86Å; M40-F186 HydrophobicContact SD-CZ 4.45Å; F43-F186 WeakPolarHBondContact CA-O 3.2Å; F43-F186 HydrophobicContact CB-CB 4.05Å; F43-F186 HydrophobicContact CB-CD1 4.19Å; F43-F186 HydrophobicContact CD2-CD1 4.15Å; F43-F186 WeakPolarHBondContact CD2-O 3.33Å; F43-F186 HydrophobicContact CG-CD1 4.5Å; Y182-F186 HydrophobicContact CD1-CE2 4.41Å; Y182-F186 WeakPolarHBondContact O-CB 3.12Å; Y182-F186 VanDerWaalsContact O-CD2 3.26Å; Y182-F186 WeakPolarHBondContact O-CD2 3.24Å; Y182-F186 PolarHBondContact O-N 2.86Å; H183-F186 PolarHBondContact O-N 2.83Å; F186-G190 PolarHBondContact O-N 3.38Å
187	T	93.7	Very high	90.6	Very high	2 Å²	2	27.5 Å²	27.5	1%	0.012	13%	0.13	C	C	.	.	H	α-helix	trans	-60.8	-54.7	169.4	-56.8	0	0	0	0	109.8	E46 H183 A184 L185 F189 G190 G191 Y439	E46-T187 HydrophobicContact CB-CG2 3.89Å; E46-T187 VanDerWaalsContact CD-CG2 3.49Å; E46-T187 HydrophobicContact CG-CG2 3.59Å; E46-T187 WeakPolarHBondContact CG-O 3.34Å; H183-T187 WeakPolarHBondContact O-CB 3.32Å; H183-T187 PolarHBondContact O-N 2.79Å; H183-T187 PolarHBondContact O-OG1 3.29Å; A184-T187 PolarHBondContact O-N 2.94Å; L185-T187 VanDerWaalsContact C-N 3.35Å; L185-T187 PolarHBondContact O-N 3.14Å; T187-F189 VanDerWaalsContact C-N 3.3Å; T187-F189 PolarHBondContact O-N 3.06Å; T187-G190 PolarHBondContact O-N 3.2Å; T187-G191 PolarHBondContact O-N 3.33Å; T187-Y439 HydrophobicContact CG2-CE2 4.08Å
188	G	92.5	Very high	90	Very high	4 Å²	4	25.1 Å²	25.1	4%	0.041	12%	0.122	C	C	.	.	H	α-helix	trans	-60.1	-39.3	179.3	0	0	0	0	0	113	A184 L185 A192 S378	A184-G188 PolarHBondContact O-N 3.27Å; L185-G188 PolarHBondContact O-N 2.87Å; G188-A192 WeakPolarHBondContact O-CB 3.4Å; G188-A192 PolarHBondContact O-N 3.35Å; G188-S378 CarbonylContact C-O 3.57Å; G188-S378 WeakPolarHBondContact CA-O 3.34Å; G188-S378 CarbonylContact O-C 3.46Å; G188-S378 WeakPolarHBondContact O-CB 3.44Å
189	F	93.8	Very high	89.4	Confident	100 Å²	100	25.1 Å²	25.1	44%	0.439	13%	0.133	S	C	.	.	H	α-helix	trans	-69.4	-40.4	177.2	-167.9	-125.8	0	0	0	112.8	F43 L185 T187 A192 L193	F43-F189 HydrophobicContact CD2-CB 4.35Å; F43-F189 AromaticContact CD2-CD1 3.88Å; F43-F189 HydrophobicContact CD2-CD1 3.88Å; F43-F189 HydrophobicContact CE2-CB 4.38Å; F43-F189 AromaticContact CE2-CD1 3.39Å; F43-F189 HydrophobicContact CE2-CD1 3.39Å; F43-F189 AromaticContact CE2-CE1 3.92Å; F43-F189 HydrophobicContact CE2-CE1 3.92Å; F43-F189 HydrophobicContact CE2-CG 4.12Å; F43-F189 HydrophobicContact CZ-CD1 4.47Å; L185-F189 PolarHBondContact O-N 3.36Å; T187-F189 VanDerWaalsContact C-N 3.3Å; T187-F189 PolarHBondContact O-N 3.06Å; F189-A192 PolarHBondContact O-N 2.87Å; F189-L193 HydrophobicContact CD1-CD1 4.34Å; F189-L193 HydrophobicContact CE1-CD1 3.82Å; F189-L193 HydrophobicContact CE2-CD1 4.27Å; F189-L193 HydrophobicContact CE2-CG 4.42Å; F189-L193 HydrophobicContact CZ-CD1 3.78Å; F189-L193 HydrophobicContact CZ-CG 4.39Å; F189-L193 PolarHBondContact O-N 2.71Å; F189-L193 VanDerWaalsContact O-N 3.13Å
190	G	94.1	Very high	88.8	Confident	0 Å²	0	28 Å²	28	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-61.3	-48.1	174.4	0	0	0	0	0	111.7	F43 F47 F186 T187 A192 L193 G194	F43-G190 VanDerWaalsContact CD2-CA 3.42Å; F43-G190 VanDerWaalsContact CE2-CA 3.48Å; F47-G190 WeakPolarHBondContact CA-O 3.27Å; F186-G190 PolarHBondContact O-N 3.38Å; T187-G190 PolarHBondContact O-N 3.2Å; G190-A192 PolarHBondContact O-N 3.48Å; G190-L193 PolarHBondContact O-N 3.44Å; G190-G194 PolarHBondContact O-N 3.02Å
191	G	92.3	Very high	88.1	Confident	1 Å²	1	31.9 Å²	31.9	1%	0.01	17%	0.169	C	C	.	.	H	α-helix	trans	-59.4	-44.6	176.2	0	0	0	0	0	112.7	A50 T187 L193 G194 Y195	A50-G191 WeakPolarHBondContact CB-O 3.49Å; T187-G191 PolarHBondContact O-N 3.33Å; G191-L193 PolarHBondContact O-N 2.86Å; G191-G194 PolarHBondContact O-N 2.91Å; G191-Y195 WeakPolarHBondContact O-CD2 3.01Å; G191-Y195 PolarHBondContact O-N 3.16Å
192	A	91.9	Very high	87.4	Confident	7 Å²	7	31.9 Å²	31.9	6%	0.058	17%	0.168	C	C	.	.	H	α-helix	trans	-59	-45.7	177.6	0	0	0	0	0	112.4	G188 F189 G190 L196 V379	G188-A192 WeakPolarHBondContact O-CB 3.4Å; G188-A192 PolarHBondContact O-N 3.35Å; F189-A192 PolarHBondContact O-N 2.87Å; G190-A192 PolarHBondContact O-N 3.48Å; A192-L196 WeakPolarHBondContact O-CB 3.44Å; A192-L196 PolarHBondContact O-N 2.65Å; A192-V379 HydrophobicContact CB-CG2 3.74Å
193	L	92.6	Very high	86.2	Confident	59 Å²	59	31.9 Å²	31.9	31%	0.309	18%	0.179	S	C	.	.	H	α-helix	trans	-71.3	-33	178.1	-71.1	177.8	0	0	0	112.8	F43 F47 F189 G190 G191 L196 L197	F43-L193 HydrophobicContact CE2-CD1 3.92Å; F43-L193 HydrophobicContact CZ-CD1 3.72Å; F47-L193 HydrophobicContact CD2-CB 3.92Å; F47-L193 HydrophobicContact CE2-CB 3.94Å; F189-L193 HydrophobicContact CD1-CD1 4.34Å; F189-L193 HydrophobicContact CE1-CD1 3.82Å; F189-L193 HydrophobicContact CE2-CD1 4.27Å; F189-L193 HydrophobicContact CE2-CG 4.42Å; F189-L193 HydrophobicContact CZ-CD1 3.78Å; F189-L193 HydrophobicContact CZ-CG 4.39Å; F189-L193 PolarHBondContact O-N 2.71Å; F189-L193 VanDerWaalsContact O-N 3.13Å; G190-L193 PolarHBondContact O-N 3.44Å; G191-L193 PolarHBondContact O-N 2.86Å; L193-L196 HydrophobicContact CD2-CD2 4.28Å; L193-L196 PolarHBondContact O-N 3.3Å; L193-L197 PolarHBondContact O-N 3.3Å
194	G	90.5	Very high	85.1	Confident	0 Å²	0	39.4 Å²	39.4	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-66.4	-45.6	174.7	0	0	0	0	0	112.3	G190 G191 L196 L197 G198	G190-G194 PolarHBondContact O-N 3.02Å; G191-G194 PolarHBondContact O-N 2.91Å; G194-L196 VanDerWaalsContact C-N 3.29Å; G194-L196 PolarHBondContact O-N 3.14Å; G194-L197 WeakPolarHBondContact O-CB 3.39Å; G194-L197 PolarHBondContact O-N 3.4Å; G194-G198 PolarHBondContact O-N 3.47Å
195	Y	86	Confident	84.4	Confident	45 Å²	45	43.4 Å²	43.4	18%	0.176	24%	0.235	C	C	.	.	H	α-helix	trans	-63.8	-34.6	172.9	-69.6	-54.2	0	0	0	112.3	A50 A53 G191 G198 A199 L374	A50-Y195 HydrophobicContact CB-CD1 3.95Å; A50-Y195 HydrophobicContact CB-CD2 4.02Å; A50-Y195 HydrophobicContact CB-CE1 3.91Å; A50-Y195 HydrophobicContact CB-CE2 3.96Å; A50-Y195 HydrophobicContact CB-CG 4Å; A53-Y195 HydrophobicContact CB-CE1 4.18Å; G191-Y195 WeakPolarHBondContact O-CD2 3.01Å; G191-Y195 PolarHBondContact O-N 3.16Å; Y195-G198 CarbonylContact O-C 3.56Å; Y195-G198 VanDerWaalsContact O-CA 3.29Å; Y195-G198 WeakPolarHBondContact O-CA 3.13Å; Y195-G198 PolarHBondContact O-N 2.99Å; Y195-A199 PolarHBondContact O-N 3.22Å; Y195-L374 HydrophobicContact CE2-CB 4.34Å
196	L	86.9	Confident	83.4	Confident	68 Å²	68	50 Å²	50	36%	0.356	26%	0.264	S	S	.	.	H	α-helix	trans	-67.4	-42.5	174.9	-175.3	65.6	0	0	0	112	A192 L193 G194 G198 A199 I200 W372	A192-L196 WeakPolarHBondContact O-CB 3.44Å; A192-L196 PolarHBondContact O-N 2.65Å; L193-L196 HydrophobicContact CD2-CD2 4.28Å; L193-L196 PolarHBondContact O-N 3.3Å; G194-L196 VanDerWaalsContact C-N 3.29Å; G194-L196 PolarHBondContact O-N 3.14Å; L196-G198 PolarHBondContact O-N 2.89Å; L196-A199 PolarHBondContact O-N 3.37Å; L196-A199 VanDerWaalsContact O-N 3.1Å; L196-I200 WeakPolarHBondContact O-CG1 3.43Å; L196-I200 PolarHBondContact O-N 3.3Å; L196-W372 HydrophobicContact CD1-CH2 4.33Å
197	L	83.8	Confident	82.2	Confident	19 Å²	19	51.2 Å²	51.2	10%	0.099	27%	0.272	C	S	.	.	H	α-helix	trans	-58.8	-39.9	172	-164.1	86	0	0	0	110.5	F47 V51 L193 G194 A199 I200 W202 M218 F221	F47-L197 HydrophobicContact CE1-CD2 4.16Å; F47-L197 HydrophobicContact CZ-CB 4.33Å; F47-L197 HydrophobicContact CZ-CD2 3.83Å; F47-L197 HydrophobicContact CZ-CG 4.46Å; V51-L197 HydrophobicContact CG2-CB 4.3Å; V51-L197 HydrophobicContact CG2-CD2 3.76Å; L193-L197 PolarHBondContact O-N 3.3Å; G194-L197 WeakPolarHBondContact O-CB 3.39Å; G194-L197 PolarHBondContact O-N 3.4Å; L197-A199 PolarHBondContact O-N 2.81Å; L197-I200 PolarHBondContact O-N 2.84Å; L197-W202 HydrophobicContact CD1-CH2 4.07Å; L197-W202 HydrophobicContact CD1-CZ2 3.4Å; L197-W202 VanDerWaalsContact CD1-CZ2 3.4Å; L197-W202 HydrophobicContact CG-CZ2 4.03Å; L197-W202 PolarHBondContact O-NE1 3.33Å; L197-W202 VanDerWaalsContact O-NE1 3.09Å; L197-M218 HydrophobicContact CD2-SD 3.55Å; L197-M218 VanDerWaalsContact CD2-SD 3.55Å; L197-M218 HydrophobicContact CG-SD 3.8Å; L197-F221 HydrophobicContact CD1-CB 4.4Å; L197-F221 HydrophobicContact CD1-CD2 4.37Å; L197-F221 HydrophobicContact CD1-CG 4.45Å; L197-F221 HydrophobicContact CD2-CB 4.17Å
198	G	71.9	Confident	80.8	Confident	12 Å²	12	51.4 Å²	51.4	12%	0.124	28%	0.275	C	S	.	.	H	α-helix	trans	-44.8	-52.6	166	0	0	0	0	0	114.5	Y55 G194 Y195 L196 I200	Y55-G198 PolarHBondContact OH-O 3.48Å; G194-G198 PolarHBondContact O-N 3.47Å; Y195-G198 CarbonylContact O-C 3.56Å; Y195-G198 VanDerWaalsContact O-CA 3.29Å; Y195-G198 WeakPolarHBondContact O-CA 3.13Å; Y195-G198 PolarHBondContact O-N 2.99Å; L196-G198 PolarHBondContact O-N 2.89Å; G198-I200 PolarHBondContact O-N 3.18Å
199	A	73.5	Confident	79.6	Confident	61 Å²	61	61.9 Å²	61.9	50%	0.504	31%	0.313	S	S	.	.	H	α-helix	trans	-81.7	-9.9	-170.8	0	0	0	0	0	114.8	Y195 L196 L197	Y195-A199 PolarHBondContact O-N 3.22Å; L196-A199 PolarHBondContact O-N 3.37Å; L196-A199 VanDerWaalsContact O-N 3.1Å; L197-A199 PolarHBondContact O-N 2.81Å
200	I	77.6	Confident	78.6	Confident	61 Å²	61	64 Å²	64	31%	0.313	33%	0.328	S	S	.	.	S	Bend	trans	-82.3	129.7	179	-66.3	164.2	0	0	0	109.3	L196 L197 G198 W202	L196-I200 WeakPolarHBondContact O-CG1 3.43Å; L196-I200 PolarHBondContact O-N 3.3Å; L197-I200 PolarHBondContact O-N 2.84Å; G198-I200 PolarHBondContact O-N 3.18Å; I200-W202 HydrophobicContact CB-CZ2 4.05Å; I200-W202 HydrophobicContact CD1-CH2 4.49Å; I200-W202 HydrophobicContact CD1-CZ2 3.94Å; I200-W202 HydrophobicContact CG2-CD2 4.01Å; I200-W202 HydrophobicContact CG2-CE3 4.49Å; I200-W202 HydrophobicContact CG2-CG 4.37Å; I200-W202 HydrophobicContact CG2-CH2 4.43Å; I200-W202 HydrophobicContact CG2-CZ2 3.9Å; I200-W202 PolarHBondContact O-N 3.35Å; I200-W202 PolarHBondContact O-NE1 2.93Å
201	D	73.6	Confident	77.6	Confident	82 Å²	82	66.6 Å²	66.6	44%	0.439	34%	0.342	S	S	.	.			trans	-80.2	97.8	172	-174.4	-12.4	0	0	0	110.7	A203 H204	D201-A203 VanDerWaalsContact C-N 3.31Å; D201-A203 WeakPolarHBondContact OD1-CB 3.49Å; D201-A203 PolarHBondContact OD1-N 2.7Å; D201-H204 IonicContact OD2-CD2 3.5Å; D201-H204 PolarHBondContact OD2-CD2 2.87Å; D201-H204 IonicContact OD2-NE2 3.65Å
202	W	76.2	Confident	76.6	Confident	21 Å²	21	69 Å²	69	8%	0.08	37%	0.367	C	S	.	.			trans	-77	-16.8	-179.1	-61.2	86.9	0	0	0	113.4	L197 I200 H204 L205 L207 G208 V217 M218 F221	L197-W202 HydrophobicContact CD1-CH2 4.07Å; L197-W202 HydrophobicContact CD1-CZ2 3.4Å; L197-W202 VanDerWaalsContact CD1-CZ2 3.4Å; L197-W202 HydrophobicContact CG-CZ2 4.03Å; L197-W202 PolarHBondContact O-NE1 3.33Å; L197-W202 VanDerWaalsContact O-NE1 3.09Å; I200-W202 HydrophobicContact CB-CZ2 4.05Å; I200-W202 HydrophobicContact CD1-CH2 4.49Å; I200-W202 HydrophobicContact CD1-CZ2 3.94Å; I200-W202 HydrophobicContact CG2-CD2 4.01Å; I200-W202 HydrophobicContact CG2-CE3 4.49Å; I200-W202 HydrophobicContact CG2-CG 4.37Å; I200-W202 HydrophobicContact CG2-CH2 4.43Å; I200-W202 HydrophobicContact CG2-CZ2 3.9Å; I200-W202 PolarHBondContact O-N 3.35Å; I200-W202 PolarHBondContact O-NE1 2.93Å; W202-H204 PolarHBondContact O-N 2.94Å; W202-L205 HydrophobicContact CE3-CD2 4.31Å; W202-L205 HydrophobicContact CZ3-CD2 4.29Å; W202-L205 PolarHBondContact O-N 3.41Å; W202-L207 HydrophobicContact CE3-CD2 4.3Å; W202-L207 HydrophobicContact CZ3-CD2 3.97Å; W202-G208 WeakPolarHBondContact O-CA 3.22Å; W202-V217 HydrophobicContact CD2-CG1 3.77Å; W202-V217 HydrophobicContact CE3-CG1 3.62Å; W202-V217 HydrophobicContact CG-CG1 4.19Å; W202-V217 HydrophobicContact CZ3-CG1 4.12Å; W202-M218 HydrophobicContact CG-CE 4.02Å; W202-F221 HydrophobicContact CE3-CE2 4.49Å; W202-F221 HydrophobicContact CH2-CD2 4.31Å; W202-F221 AromaticContact CH2-CE2 3.77Å; W202-F221 HydrophobicContact CH2-CE2 3.77Å; W202-F221 HydrophobicContact CH2-CZ 4.37Å; W202-F221 AromaticContact CZ3-CE2 3.75Å; W202-F221 HydrophobicContact CZ3-CE2 3.75Å; W202-F221 HydrophobicContact CZ3-CZ 4.38Å
203	A	67.2	Low	76	Confident	53 Å²	53	71.6 Å²	71.6	44%	0.438	38%	0.382	S	S	.	.	S	Bend	trans	-65.9	-32.4	-179	0	0	0	0	0	111.4	D201 E214	D201-A203 VanDerWaalsContact C-N 3.31Å; D201-A203 WeakPolarHBondContact OD1-CB 3.49Å; D201-A203 PolarHBondContact OD1-N 2.7Å; A203-E214 HydrophobicContact CB-CG 4.14Å
204	H	70	Confident	75.4	Confident	160 Å²	160	72.7 Å²	72.7	74%	0.741	39%	0.385	S	S	*	.	S	Bend	trans	-84.5	-17.9	177.9	-71.2	-45.6	0	0	0	114.6	D201 W202	D201-H204 IonicContact OD2-CD2 3.5Å; D201-H204 PolarHBondContact OD2-CD2 2.87Å; D201-H204 IonicContact OD2-NE2 3.65Å; W202-H204 PolarHBondContact O-N 2.94Å
205	L	76.2	Confident	75.1	Confident	86 Å²	86	74.8 Å²	74.8	45%	0.45	40%	0.395	S	S	.	.	S	Bend	trans	-81.9	144.5	177.1	-96	69.2	0	0	0	111.4	W202 L207 G208	W202-L205 HydrophobicContact CE3-CD2 4.31Å; W202-L205 HydrophobicContact CZ3-CD2 4.29Å; W202-L205 PolarHBondContact O-N 3.41Å; L205-L207 PolarHBondContact O-N 2.83Å; L205-G208 PolarHBondContact O-N 2.91Å
206	E	73.1	Confident	75.1	Confident	173 Å²	173	75.3 Å²	75.3	81%	0.808	40%	0.398	S	S	*	.	H	α-helix	trans	-55.1	-28.5	176.6	-64.4	-172.9	160.7	0	0	112.9	G208 R209 L210	E206-G208 VanDerWaalsContact C-N 3.33Å; E206-G208 PolarHBondContact O-N 3.48Å; E206-R209 WeakPolarHBondContact O-CB 3.32Å; E206-R209 PolarHBondContact O-N 3.44Å; E206-R209 VanDerWaalsContact O-N 3.17Å; E206-L210 PolarHBondContact O-N 3.04Å
207	L	68.9	Low	75.1	Confident	61 Å²	61	72 Å²	72	32%	0.319	38%	0.382	S	S	.	.	H	α-helix	trans	-63.7	-36.9	178	-149.1	89.5	0	0	0	112.6	W202 L205 R209 L210 L211 V217 F221	W202-L207 HydrophobicContact CE3-CD2 4.3Å; W202-L207 HydrophobicContact CZ3-CD2 3.97Å; L205-L207 PolarHBondContact O-N 2.83Å; L207-R209 VanDerWaalsContact C-N 3.29Å; L207-R209 PolarHBondContact O-N 3.48Å; L207-L210 PolarHBondContact O-N 3.44Å; L207-L211 HydrophobicContact CD2-CD1 4.09Å; L207-L211 HydrophobicContact CG-CD1 4.12Å; L207-L211 PolarHBondContact O-N 3.12Å; L207-V217 HydrophobicContact CD2-CG1 3.97Å; L207-F221 HydrophobicContact CD2-CE2 3.4Å; L207-F221 VanDerWaalsContact CD2-CE2 3.4Å; L207-F221 HydrophobicContact CD2-CZ 3.52Å
208	G	63.8	Low	75.2	Confident	7 Å²	7	71.1 Å²	71.1	7%	0.072	38%	0.377	C	S	.	.	H	α-helix	trans	-63.5	-37.8	174.1	0	0	0	0	0	111.8	W202 L205 E206 G212	W202-G208 WeakPolarHBondContact O-CA 3.22Å; L205-G208 PolarHBondContact O-N 2.91Å; E206-G208 VanDerWaalsContact C-N 3.33Å; E206-G208 PolarHBondContact O-N 3.48Å; G208-G212 CarbonylContact O-C 3.53Å; G208-G212 PolarHBondContact O-N 2.89Å; G208-G212 VanDerWaalsContact O-N 3.08Å
209	R	67.8	Low	76.1	Confident	224 Å²	224	73.2 Å²	73.2	85%	0.845	38%	0.383	S	S	*	.	H	α-helix	trans	-69.8	-33	175.6	-161.1	179.8	-62.1	-175.7	2.8	112.6	E206 L207	E206-R209 WeakPolarHBondContact O-CB 3.32Å; E206-R209 PolarHBondContact O-N 3.44Å; E206-R209 VanDerWaalsContact O-N 3.17Å; L207-R209 VanDerWaalsContact C-N 3.29Å; L207-R209 PolarHBondContact O-N 3.48Å
210	L	72.8	Confident	77	Confident	143 Å²	143	75.2 Å²	75.2	75%	0.749	38%	0.38	S	S	*	.	H	α-helix	trans	-74.4	-44.2	179.5	-172.8	71.6	0	0	0	112.4	E206 L207	E206-L210 PolarHBondContact O-N 3.04Å; L207-L210 PolarHBondContact O-N 3.44Å
211	L	72.1	Confident	77.6	Confident	56 Å²	56	74.9 Å²	74.9	29%	0.293	38%	0.376	S	S	.	.	H	α-helix	trans	-89.2	-7.7	-174.9	-72.8	166.7	0	0	0	113.6	L207 Q216 V217 F220	L207-L211 HydrophobicContact CD2-CD1 4.09Å; L207-L211 HydrophobicContact CG-CD1 4.12Å; L207-L211 PolarHBondContact O-N 3.12Å; L211-Q216 WeakPolarHBondContact O-CB 3.06Å; L211-Q216 PolarHBondContact O-OE1 3.22Å; L211-V217 HydrophobicContact CB-CG2 3.78Å; L211-V217 HydrophobicContact CD1-CB 4.38Å; L211-V217 HydrophobicContact CD1-CG1 4.42Å; L211-V217 HydrophobicContact CD1-CG2 3.94Å; L211-V217 HydrophobicContact CG-CG2 4.49Å; L211-F220 HydrophobicContact CD1-CB 4.49Å; L211-F220 HydrophobicContact CD1-CD1 4.37Å; L211-F220 HydrophobicContact CD1-CG 4.48Å
212	G	72.2	Confident	78.6	Confident	51 Å²	51	71 Å²	71	53%	0.526	36%	0.356	S	S	.	.	S	Bend	trans	107.9	-68.7	169.3	0	0	0	0	0	112.6	G208	G208-G212 CarbonylContact O-C 3.53Å; G208-G212 PolarHBondContact O-N 2.89Å; G208-G212 VanDerWaalsContact O-N 3.08Å
213	T	78.7	Confident	79.5	Confident	61 Å²	61	70.7 Å²	70.7	37%	0.374	36%	0.358	S	S	.	.	S	Bend	trans	-127.1	155.7	-179.3	57.7	0	0	0	0	111.1	F215 Q216 V217	T213-F215 PolarHBondContact O-N 3.46Å; T213-Q216 WeakPolarHBondContact O-CB 3.4Å; T213-Q216 PolarHBondContact O-N 3.39Å; T213-Q216 VanDerWaalsContact OG1-CD 3.28Å; T213-Q216 VanDerWaalsContact OG1-CG 3.25Å; T213-Q216 WeakPolarHBondContact OG1-CG 3.01Å; T213-Q216 PolarHBondContact OG1-N 3.07Å; T213-Q216 PolarHBondContact OG1-OE1 3.44Å; T213-V217 PolarHBondContact O-N 2.84Å; T213-V217 VanDerWaalsContact O-N 3.11Å
214	E	80.9	Confident	80.9	Confident	83 Å²	83	72.7 Å²	72.7	39%	0.388	36%	0.361	S	S	.	.	H	α-helix	trans	-50.5	-44.8	174.1	-48.9	166.5	-143.7	0	0	110.7	A203 Q216 V217 M218	A203-E214 HydrophobicContact CB-CG 4.14Å; E214-Q216 VanDerWaalsContact C-N 3.33Å; E214-Q216 PolarHBondContact O-N 2.9Å; E214-V217 WeakPolarHBondContact O-CB 3.45Å; E214-V217 PolarHBondContact O-N 3.03Å; E214-M218 WeakPolarHBondContact O-CG 3.33Å; E214-M218 PolarHBondContact O-N 3.49Å
215	F	84.4	Confident	82.1	Confident	44 Å²	44	66.7 Å²	66.7	19%	0.193	34%	0.335	C	S	.	.	H	α-helix	trans	-63.1	-34.8	178.2	-55.3	-33.5	0	0	0	113.4	Y55 V59 L121 T213 M218 F219	Y55-F215 HydrophobicContact CD1-CE1 4.28Å; V59-F215 HydrophobicContact CB-CZ 4.47Å; V59-F215 HydrophobicContact CG2-CD1 3.67Å; V59-F215 HydrophobicContact CG2-CD2 4.22Å; V59-F215 HydrophobicContact CG2-CE1 3.44Å; V59-F215 VanDerWaalsContact CG2-CE1 3.44Å; V59-F215 HydrophobicContact CG2-CE2 4.01Å; V59-F215 HydrophobicContact CG2-CG 4.08Å; V59-F215 HydrophobicContact CG2-CZ 3.62Å; L121-F215 HydrophobicContact CB-CB 4.42Å; L121-F215 HydrophobicContact CD2-CB 4.12Å; L121-F215 HydrophobicContact CD2-CD1 4.48Å; T213-F215 PolarHBondContact O-N 3.46Å; F215-M218 PolarHBondContact O-N 3.09Å; F215-F219 WeakPolarHBondContact O-CB 3.36Å; F215-F219 PolarHBondContact O-N 3.36Å
216	Q	85.8	Confident	83	Confident	55 Å²	55	62.6 Å²	62.6	26%	0.257	31%	0.314	S	S	.	.	H	α-helix	trans	-70.8	-36.2	175.8	-77	166.9	-36.3	0	0	112	N122 L211 T213 E214 F219 F220	N122-Q216 WeakPolarHBondContact OD1-CG 3.48Å; L211-Q216 WeakPolarHBondContact O-CB 3.06Å; L211-Q216 PolarHBondContact O-OE1 3.22Å; T213-Q216 WeakPolarHBondContact O-CB 3.4Å; T213-Q216 PolarHBondContact O-N 3.39Å; T213-Q216 VanDerWaalsContact OG1-CD 3.28Å; T213-Q216 VanDerWaalsContact OG1-CG 3.25Å; T213-Q216 WeakPolarHBondContact OG1-CG 3.01Å; T213-Q216 PolarHBondContact OG1-N 3.07Å; T213-Q216 PolarHBondContact OG1-OE1 3.44Å; E214-Q216 VanDerWaalsContact C-N 3.33Å; E214-Q216 PolarHBondContact O-N 2.9Å; Q216-F219 PolarHBondContact O-N 3.06Å; Q216-F220 WeakPolarHBondContact O-CB 3.31Å; Q216-F220 PolarHBondContact O-N 2.74Å
217	V	85.7	Confident	84.1	Confident	0 Å²	0	57.5 Å²	57.5	0%	0	29%	0.294	C	S	.	.	H	α-helix	trans	-61.9	-48	172.1	179.8	0	0	0	0	110.3	W202 L207 L211 T213 E214 F219 F220 F221	W202-V217 HydrophobicContact CD2-CG1 3.77Å; W202-V217 HydrophobicContact CE3-CG1 3.62Å; W202-V217 HydrophobicContact CG-CG1 4.19Å; W202-V217 HydrophobicContact CZ3-CG1 4.12Å; L207-V217 HydrophobicContact CD2-CG1 3.97Å; L211-V217 HydrophobicContact CB-CG2 3.78Å; L211-V217 HydrophobicContact CD1-CB 4.38Å; L211-V217 HydrophobicContact CD1-CG1 4.42Å; L211-V217 HydrophobicContact CD1-CG2 3.94Å; L211-V217 HydrophobicContact CG-CG2 4.49Å; T213-V217 PolarHBondContact O-N 2.84Å; T213-V217 VanDerWaalsContact O-N 3.11Å; E214-V217 WeakPolarHBondContact O-CB 3.45Å; E214-V217 PolarHBondContact O-N 3.03Å; V217-F219 VanDerWaalsContact C-N 3.35Å; V217-F219 PolarHBondContact O-N 2.81Å; V217-F220 PolarHBondContact O-N 3.25Å; V217-F221 HydrophobicContact CG1-CD2 3.65Å; V217-F221 HydrophobicContact CG1-CE2 3.54Å; V217-F221 WeakPolarHBondContact O-CD2 3.34Å; V217-F221 PolarHBondContact O-N 3.26Å
218	M	86	Confident	85.5	Confident	0 Å²	0	60 Å²	60	0%	0	31%	0.307	C	S	.	.	H	α-helix	trans	-59.2	-46.4	177	-65.1	-59.3	171.4	0	0	111.9	V51 Y55 L121 L197 W202 E214 F215 F220 F221 S222	V51-M218 HydrophobicContact CG1-CB 4.3Å; V51-M218 HydrophobicContact CG1-SD 4.44Å; Y55-M218 HydrophobicContact CD2-CE 4.2Å; Y55-M218 HydrophobicContact CD2-CG 4.31Å; Y55-M218 HydrophobicContact CD2-SD 4.34Å; Y55-M218 HydrophobicContact CE1-CE 4.31Å; Y55-M218 HydrophobicContact CE2-CE 3.22Å; Y55-M218 HydrophobicContact CE2-CG 4.15Å; Y55-M218 HydrophobicContact CE2-SD 3.78Å; Y55-M218 WeakPolarHBondContact OH-CE 3.3Å; L121-M218 HydrophobicContact CD1-CB 4.28Å; L197-M218 HydrophobicContact CD2-SD 3.55Å; L197-M218 VanDerWaalsContact CD2-SD 3.55Å; L197-M218 HydrophobicContact CG-SD 3.8Å; W202-M218 HydrophobicContact CG-CE 4.02Å; E214-M218 WeakPolarHBondContact O-CG 3.33Å; E214-M218 PolarHBondContact O-N 3.49Å; F215-M218 PolarHBondContact O-N 3.09Å; M218-F220 VanDerWaalsContact C-N 3.33Å; M218-F220 PolarHBondContact O-N 2.93Å; M218-F221 PolarHBondContact O-N 3.09Å; M218-S222 WeakPolarHBondContact O-CB 3.5Å; M218-S222 PolarHBondContact O-N 3.44Å; M218-S222 PolarHBondContact O-OG 3.24Å
219	F	91.7	Very high	87	Confident	56 Å²	56	59.8 Å²	59.8	25%	0.246	31%	0.305	C	S	.	.	H	α-helix	trans	-58.6	-47.4	177.4	174.7	-112.4	0	0	0	110.7	M117 A118 L121 F215 Q216 V217 S222 A223	M117-F219 HydrophobicContact CB-CD2 4.45Å; M117-F219 HydrophobicContact CB-CE2 4.49Å; M117-F219 HydrophobicContact CG-CD2 3.87Å; M117-F219 HydrophobicContact CG-CE2 4.37Å; M117-F219 HydrophobicContact SD-CD2 3.99Å; M117-F219 HydrophobicContact SD-CE2 4.5Å; A118-F219 VanDerWaalsContact CA-CE2 3.48Å; A118-F219 HydrophobicContact CB-CE2 3.63Å; A118-F219 HydrophobicContact CB-CZ 3.76Å; L121-F219 HydrophobicContact CB-CB 4.19Å; L121-F219 HydrophobicContact CD1-CB 3.61Å; L121-F219 HydrophobicContact CD1-CD2 4.3Å; L121-F219 HydrophobicContact CD1-CG 4.45Å; F215-F219 WeakPolarHBondContact O-CB 3.36Å; F215-F219 PolarHBondContact O-N 3.36Å; Q216-F219 PolarHBondContact O-N 3.06Å; V217-F219 VanDerWaalsContact C-N 3.35Å; V217-F219 PolarHBondContact O-N 2.81Å; F219-S222 PolarHBondContact O-N 3.37Å; F219-A223 HydrophobicContact CD2-CB 4.47Å; F219-A223 HydrophobicContact CE2-CB 4.13Å; F219-A223 HydrophobicContact CZ-CB 4.25Å; F219-A223 WeakPolarHBondContact O-CB 3.47Å; F219-A223 PolarHBondContact O-N 2.89Å
220	F	91.8	Very high	88.3	Confident	102 Å²	102	49.6 Å²	49.6	45%	0.447	27%	0.267	S	S	.	.	H	α-helix	trans	-59.2	-52.5	-179.2	175.9	-97.6	0	0	0	112.1	L211 Q216 V217 M218 L224	L211-F220 HydrophobicContact CD1-CB 4.49Å; L211-F220 HydrophobicContact CD1-CD1 4.37Å; L211-F220 HydrophobicContact CD1-CG 4.48Å; Q216-F220 WeakPolarHBondContact O-CB 3.31Å; Q216-F220 PolarHBondContact O-N 2.74Å; V217-F220 PolarHBondContact O-N 3.25Å; M218-F220 VanDerWaalsContact C-N 3.33Å; M218-F220 PolarHBondContact O-N 2.93Å; F220-L224 HydrophobicContact CE1-CD2 4.42Å; F220-L224 VanDerWaalsContact O-CB 3.22Å; F220-L224 WeakPolarHBondContact O-CB 3.41Å; F220-L224 PolarHBondContact O-N 3.41Å
221	F	91.6	Very high	89.3	Confident	55 Å²	55	46.4 Å²	46.4	24%	0.241	25%	0.253	C	S	.	.	H	α-helix	trans	-65.4	-43.4	-179.9	-77.4	-63.7	0	0	0	112.2	L197 W202 L207 V217 M218 L224 V225	L197-F221 HydrophobicContact CD1-CB 4.4Å; L197-F221 HydrophobicContact CD1-CD2 4.37Å; L197-F221 HydrophobicContact CD1-CG 4.45Å; L197-F221 HydrophobicContact CD2-CB 4.17Å; W202-F221 HydrophobicContact CE3-CE2 4.49Å; W202-F221 HydrophobicContact CH2-CD2 4.31Å; W202-F221 AromaticContact CH2-CE2 3.77Å; W202-F221 HydrophobicContact CH2-CE2 3.77Å; W202-F221 HydrophobicContact CH2-CZ 4.37Å; W202-F221 AromaticContact CZ3-CE2 3.75Å; W202-F221 HydrophobicContact CZ3-CE2 3.75Å; W202-F221 HydrophobicContact CZ3-CZ 4.38Å; L207-F221 HydrophobicContact CD2-CE2 3.4Å; L207-F221 VanDerWaalsContact CD2-CE2 3.4Å; L207-F221 HydrophobicContact CD2-CZ 3.52Å; V217-F221 HydrophobicContact CG1-CD2 3.65Å; V217-F221 HydrophobicContact CG1-CE2 3.54Å; V217-F221 WeakPolarHBondContact O-CD2 3.34Å; V217-F221 PolarHBondContact O-N 3.26Å; M218-F221 PolarHBondContact O-N 3.09Å; F221-L224 PolarHBondContact O-N 2.81Å; F221-V225 WeakPolarHBondContact O-CB 3.47Å; F221-V225 VanDerWaalsContact O-CG2 3.28Å; F221-V225 WeakPolarHBondContact O-CG2 3.3Å; F221-V225 PolarHBondContact O-N 2.89Å
222	S	93.2	Very high	90.4	Very high	0 Å²	0	45.7 Å²	45.7	0%	0	25%	0.251	C	S	.	.	H	α-helix	trans	-66.4	-43.6	-179.4	-58.6	0	0	0	0	111.8	M117 M218 F219 V225 L226	M117-S222 WeakPolarHBondContact SD-CB 3.4Å; M218-S222 WeakPolarHBondContact O-CB 3.5Å; M218-S222 PolarHBondContact O-N 3.44Å; M218-S222 PolarHBondContact O-OG 3.24Å; F219-S222 PolarHBondContact O-N 3.37Å; S222-V225 PolarHBondContact O-N 3.22Å; S222-L226 WeakPolarHBondContact O-CB 3.01Å; S222-L226 PolarHBondContact O-N 2.81Å
223	A	95.7	Very high	91.4	Very high	15 Å²	15	43.2 Å²	43.2	12%	0.124	23%	0.226	C	C	.	.	H	α-helix	trans	-64.2	-40.4	175	0	0	0	0	0	112	L114 F219 T227	L114-A223 HydrophobicContact CD2-CB 3.75Å; F219-A223 HydrophobicContact CD2-CB 4.47Å; F219-A223 HydrophobicContact CE2-CB 4.13Å; F219-A223 HydrophobicContact CZ-CB 4.25Å; F219-A223 WeakPolarHBondContact O-CB 3.47Å; F219-A223 PolarHBondContact O-N 2.89Å; A223-T227 WeakPolarHBondContact O-CB 3.31Å; A223-T227 PolarHBondContact O-N 3.26Å; A223-T227 PolarHBondContact O-OG1 3.12Å
224	L	95.5	Very high	91.9	Very high	95 Å²	95	41.9 Å²	41.9	50%	0.497	22%	0.216	S	C	.	.	H	α-helix	trans	-62.1	-51.6	176.5	178.2	65.7	0	0	0	111.3	F220 F221 T227 L228	F220-L224 HydrophobicContact CE1-CD2 4.42Å; F220-L224 VanDerWaalsContact O-CB 3.22Å; F220-L224 WeakPolarHBondContact O-CB 3.41Å; F220-L224 PolarHBondContact O-N 3.41Å; F221-L224 PolarHBondContact O-N 2.81Å; L224-T227 PolarHBondContact O-N 3.15Å; L224-L228 WeakPolarHBondContact O-CB 3.48Å; L224-L228 PolarHBondContact O-N 3.39Å
225	V	95.7	Very high	92.3	Very high	33 Å²	33	42.2 Å²	42.2	20%	0.2	23%	0.227	C	C	.	.	H	α-helix	trans	-61.3	-48.4	179.3	169.8	0	0	0	0	110.5	F43 F47 F221 S222 T227 L228 C229	F43-V225 HydrophobicContact CD1-CG1 4.21Å; F43-V225 HydrophobicContact CE1-CG1 3.7Å; F47-V225 HydrophobicContact CB-CG1 4.42Å; F47-V225 HydrophobicContact CD1-CB 4.26Å; F47-V225 HydrophobicContact CD1-CG1 4.02Å; F47-V225 HydrophobicContact CD2-CG1 4.47Å; F47-V225 HydrophobicContact CE1-CB 4.26Å; F47-V225 HydrophobicContact CE1-CG1 4.42Å; F47-V225 HydrophobicContact CE1-CG2 4.28Å; F47-V225 HydrophobicContact CG-CG1 4.04Å; F47-V225 HydrophobicContact CZ-CG2 4.26Å; F221-V225 WeakPolarHBondContact O-CB 3.47Å; F221-V225 VanDerWaalsContact O-CG2 3.28Å; F221-V225 WeakPolarHBondContact O-CG2 3.3Å; F221-V225 PolarHBondContact O-N 2.89Å; S222-V225 PolarHBondContact O-N 3.22Å; V225-T227 PolarHBondContact O-N 2.72Å; V225-L228 PolarHBondContact O-N 3.34Å; V225-C229 VanDerWaalsContact O-CB 3.26Å; V225-C229 WeakPolarHBondContact O-CB 3.45Å; V225-C229 PolarHBondContact O-N 3.32Å; V225-C229 PolarHBondContact O-SG 3.5Å
226	L	96.1	Very high	92.3	Very high	1 Å²	1	40.5 Å²	40.5	1%	0.005	22%	0.22	C	C	.	.	H	α-helix	trans	-60.3	-46.8	180	-170.9	65.6	0	0	0	111.5	M113 L114 S222 C229 F230	M113-L226 HydrophobicContact CB-CD2 3.9Å; M113-L226 HydrophobicContact CE-CD1 4.19Å; M113-L226 HydrophobicContact CE-CD2 4.4Å; L114-L226 HydrophobicContact CD2-CB 4.39Å; L114-L226 HydrophobicContact CD2-CD2 3.8Å; L114-L226 HydrophobicContact CD2-CG 4.47Å; L114-L226 HydrophobicContact CG-CD2 3.89Å; S222-L226 WeakPolarHBondContact O-CB 3.01Å; S222-L226 PolarHBondContact O-N 2.81Å; L226-C229 PolarHBondContact O-N 3.02Å; L226-F230 HydrophobicContact CD1-CD2 3.69Å; L226-F230 HydrophobicContact CD1-CE2 3.26Å; L226-F230 HydrophobicContact CD1-CZ 3.99Å; L226-F230 HydrophobicContact CG-CD2 4.16Å; L226-F230 HydrophobicContact CG-CE2 4.12Å; L226-F230 WeakPolarHBondContact O-CB 3.3Å; L226-F230 VanDerWaalsContact O-CD2 3.28Å; L226-F230 WeakPolarHBondContact O-CD2 3.33Å; L226-F230 PolarHBondContact O-N 2.98Å
227	T	96.5	Very high	92	Very high	65 Å²	65	38 Å²	38	40%	0.399	21%	0.208	S	C	.	.	H	α-helix	trans	-63	-45.3	179.6	-57.7	0	0	0	0	111.4	A223 L224 V225 T231	A223-T227 WeakPolarHBondContact O-CB 3.31Å; A223-T227 PolarHBondContact O-N 3.26Å; A223-T227 PolarHBondContact O-OG1 3.12Å; L224-T227 PolarHBondContact O-N 3.15Å; V225-T227 PolarHBondContact O-N 2.72Å; T227-T231 VanDerWaalsContact O-CB 3.28Å; T227-T231 WeakPolarHBondContact O-CB 3.49Å; T227-T231 PolarHBondContact O-N 3.28Å; T227-T231 PolarHBondContact O-OG1 3.11Å
228	L	96.7	Very high	91.5	Very high	113 Å²	113	42.7 Å²	42.7	59%	0.592	24%	0.241	S	C	*	.	H	α-helix	trans	-61	-49.4	177.1	179.6	63.7	0	0	0	110.8	L224 V225 F230 T231 V232	L224-L228 WeakPolarHBondContact O-CB 3.48Å; L224-L228 PolarHBondContact O-N 3.39Å; V225-L228 PolarHBondContact O-N 3.34Å; L228-F230 PolarHBondContact O-N 3.02Å; L228-T231 PolarHBondContact O-N 3.14Å; L228-V232 HydrophobicContact CD1-CG2 4.41Å; L228-V232 VanDerWaalsContact O-CG2 3.3Å; L228-V232 WeakPolarHBondContact O-CG2 3.2Å; L228-V232 PolarHBondContact O-N 2.93Å
229	C	96.6	Very high	91	Very high	3 Å²	3	43.7 Å²	43.7	2%	0.02	25%	0.246	C	C	.	.	H	α-helix	trans	-59.9	-45.1	179.8	-79	0	0	0	0	113.2	M40 F43 V225 L226 V232 H233	M40-C229 HydrophobicContact CB-CB 4.33Å; M40-C229 WeakPolarHBondContact CE-SG 3.48Å; M40-C229 VanDerWaalsContact O-CB 3.24Å; M40-C229 WeakPolarHBondContact O-CB 3.44Å; M40-C229 PolarHBondContact O-SG 2.98Å; F43-C229 VanDerWaalsContact CD1-SG 3.53Å; V225-C229 VanDerWaalsContact O-CB 3.26Å; V225-C229 WeakPolarHBondContact O-CB 3.45Å; V225-C229 PolarHBondContact O-N 3.32Å; V225-C229 PolarHBondContact O-SG 3.5Å; L226-C229 PolarHBondContact O-N 3.02Å; C229-V232 PolarHBondContact O-N 3.12Å; C229-H233 WeakPolarHBondContact O-CB 3.27Å; C229-H233 PolarHBondContact O-N 3.45Å
230	F	94.2	Very high	89.6	Confident	11 Å²	11	44.1 Å²	44.1	5%	0.048	26%	0.259	C	S	.	.	H	α-helix	trans	-69.8	-37.2	179.2	-87.1	-124	0	0	0	111.7	A41 I106 M113 I159 L226 L228 H233 L234	A41-F230 HydrophobicContact CB-CE2 4.42Å; I106-F230 HydrophobicContact CG2-CD1 4.46Å; I106-F230 HydrophobicContact CG2-CE1 4.29Å; M113-F230 HydrophobicContact SD-CZ 4.17Å; I159-F230 HydrophobicContact CD1-CD1 4.4Å; I159-F230 HydrophobicContact CD1-CE1 3.14Å; I159-F230 HydrophobicContact CD1-CE2 4.47Å; I159-F230 HydrophobicContact CD1-CZ 3.2Å; L226-F230 HydrophobicContact CD1-CD2 3.69Å; L226-F230 HydrophobicContact CD1-CE2 3.26Å; L226-F230 HydrophobicContact CD1-CZ 3.99Å; L226-F230 HydrophobicContact CG-CD2 4.16Å; L226-F230 HydrophobicContact CG-CE2 4.12Å; L226-F230 WeakPolarHBondContact O-CB 3.3Å; L226-F230 VanDerWaalsContact O-CD2 3.28Å; L226-F230 WeakPolarHBondContact O-CD2 3.33Å; L226-F230 PolarHBondContact O-N 2.98Å; L228-F230 PolarHBondContact O-N 3.02Å; F230-H233 PolarHBondContact O-N 2.95Å; F230-L234 WeakPolarHBondContact O-CB 3.38Å; F230-L234 VanDerWaalsContact O-CG 3.23Å; F230-L234 WeakPolarHBondContact O-CG 3.28Å; F230-L234 PolarHBondContact O-N 3.35Å
231	T	94.2	Very high	88.2	Confident	75 Å²	75	40.4 Å²	40.4	46%	0.46	25%	0.246	S	C	.	.	H	α-helix	trans	-60.8	-47.7	173.6	-58	0	0	0	0	110.4	T227 L228 H233 L234 C235	T227-T231 VanDerWaalsContact O-CB 3.28Å; T227-T231 WeakPolarHBondContact O-CB 3.49Å; T227-T231 PolarHBondContact O-N 3.28Å; T227-T231 PolarHBondContact O-OG1 3.11Å; L228-T231 PolarHBondContact O-N 3.14Å; T231-H233 PolarHBondContact O-N 3.1Å; T231-L234 PolarHBondContact O-N 3.24Å; T231-C235 WeakPolarHBondContact O-CB 3.49Å; T231-C235 PolarHBondContact O-N 3.31Å; T231-C235 PolarHBondContact O-SG 3.45Å
232	V	94.4	Very high	86.7	Confident	41 Å²	41	40.8 Å²	40.8	25%	0.248	25%	0.25	C	C	.	.	H	α-helix	trans	-61.7	-43.7	176.5	172.7	0	0	0	0	111.5	M37 M40 L228 C229 C235 S236	M37-V232 HydrophobicContact CB-CG1 3.76Å; M37-V232 HydrophobicContact CE-CG1 4.07Å; M37-V232 HydrophobicContact CG-CG1 3.82Å; M40-V232 HydrophobicContact CB-CB 4.41Å; M40-V232 HydrophobicContact CB-CG1 4.18Å; M40-V232 HydrophobicContact CG-CB 4.41Å; M40-V232 HydrophobicContact CG-CG1 3.77Å; L228-V232 HydrophobicContact CD1-CG2 4.41Å; L228-V232 VanDerWaalsContact O-CG2 3.3Å; L228-V232 WeakPolarHBondContact O-CG2 3.2Å; L228-V232 PolarHBondContact O-N 2.93Å; C229-V232 PolarHBondContact O-N 3.12Å; V232-C235 PolarHBondContact O-N 3.26Å; V232-S236 PolarHBondContact O-N 3.49Å; V232-S236 VanDerWaalsContact O-N 3.14Å
233	H	93.9	Very high	84.8	Confident	0 Å²	0	44.4 Å²	44.4	0%	0	27%	0.272	C	S	.	.	H	α-helix	trans	-61.8	-49.5	177.6	173.9	84.4	0	0	0	112.3	M37 H38 A41 Y166 C229 F230 T231 C235 S236	M37-H233 WeakPolarHBondContact O-CA 3.27Å; H38-H233 AromaticContact CD2-CE1 3.61Å; H38-H233 AromaticContact CD2-ND1 3.91Å; H38-H233 AromaticContact CE1-CE1 3.69Å; H38-H233 AromaticContact CG-CE1 3.88Å; H38-H233 AromaticContact CG-ND1 3.92Å; H38-H233 AromaticContact ND1-CE1 3.9Å; H38-H233 AromaticContact NE2-CE1 3.49Å; H38-H233 PolarHBondContact NE2-CE1 3.22Å; H38-H233 PolarHBondContact O-ND1 3.01Å; A41-H233 HydrophobicContact CB-CB 3.71Å; A41-H233 VanDerWaalsContact CB-CG 3.47Å; Y166-H233 AromaticContact CD1-CE1 3.87Å; Y166-H233 AromaticContact CD1-NE2 3.54Å; Y166-H233 AromaticContact CE1-NE2 3.63Å; C229-H233 WeakPolarHBondContact O-CB 3.27Å; C229-H233 PolarHBondContact O-N 3.45Å; F230-H233 PolarHBondContact O-N 2.95Å; T231-H233 PolarHBondContact O-N 3.1Å; H233-C235 PolarHBondContact O-N 2.93Å; H233-S236 VanDerWaalsContact O-CB 3.27Å; H233-S236 WeakPolarHBondContact O-CB 3.21Å; H233-S236 PolarHBondContact O-N 2.9Å; H233-S236 PolarHBondContact O-OG 3.49Å
234	L	90.2	Very high	82.9	Confident	32 Å²	32	49.9 Å²	49.9	17%	0.168	30%	0.295	C	S	.	.	H	α-helix	trans	-65.9	-23.7	179.3	-68	171.5	0	0	0	112.3	R103 I106 L107 F230 T231	R103-L234 HydrophobicContact CB-CD2 4.11Å; R103-L234 HydrophobicContact CG-CD2 4.14Å; R103-L234 PolarHBondContact NH1-O 2.94Å; R103-L234 PolarHBondContact NH2-O 2.81Å; I106-L234 HydrophobicContact CG2-CD2 4.41Å; L107-L234 HydrophobicContact CB-CD1 4.1Å; L107-L234 HydrophobicContact CD1-CD1 3.78Å; L107-L234 HydrophobicContact CG-CD1 4.41Å; F230-L234 WeakPolarHBondContact O-CB 3.38Å; F230-L234 VanDerWaalsContact O-CG 3.23Å; F230-L234 WeakPolarHBondContact O-CG 3.28Å; F230-L234 PolarHBondContact O-N 3.35Å; T231-L234 PolarHBondContact O-N 3.24Å
235	C	88.7	Confident	81	Confident	91 Å²	91	49.6 Å²	49.6	62%	0.615	30%	0.297	S	S	*	.	T	Hydrogen-bonded Turn	trans	-88.1	-5.6	174.1	-64	0	0	0	0	114.3	T231 V232 H233	T231-C235 WeakPolarHBondContact O-CB 3.49Å; T231-C235 PolarHBondContact O-N 3.31Å; T231-C235 PolarHBondContact O-SG 3.45Å; V232-C235 PolarHBondContact O-N 3.26Å; H233-C235 PolarHBondContact O-N 2.93Å
236	S	84.8	Confident	78.9	Confident	7 Å²	7	51.5 Å²	51.5	5%	0.049	32%	0.316	C	S	.	.	T	Hydrogen-bonded Turn	trans	-69.6	-59.3	-168.7	65.9	0	0	0	0	115	H38 V232 H233	H38-S236 PolarHBondContact ND1-OG 3.19Å; V232-S236 PolarHBondContact O-N 3.49Å; V232-S236 VanDerWaalsContact O-N 3.14Å; H233-S236 VanDerWaalsContact O-CB 3.27Å; H233-S236 WeakPolarHBondContact O-CB 3.21Å; H233-S236 PolarHBondContact O-N 2.9Å; H233-S236 PolarHBondContact O-OG 3.49Å
237	I	79.8	Confident	76.6	Confident	3 Å²	3	59.5 Å²	59.5	2%	0.015	35%	0.351	C	S	.	.	S	Bend	trans	-138	108.3	-172	-57.6	171.6	0	0	0	109.9	R30 R34 R103 Y166 V170 E239	R30-I237 HydrophobicContact CG-CD1 4.43Å; R34-I237 HydrophobicContact CB-CD1 4.28Å; R34-I237 HydrophobicContact CB-CG1 3.9Å; R103-I237 PolarHBondContact NH2-O 3.37Å; Y166-I237 PolarHBondContact OH-O 3.31Å; V170-I237 HydrophobicContact CB-CG2 3.87Å; V170-I237 HydrophobicContact CG1-CG2 4.23Å; V170-I237 HydrophobicContact CG2-CB 4.37Å; V170-I237 HydrophobicContact CG2-CD1 4.01Å; V170-I237 HydrophobicContact CG2-CG2 3.95Å; I237-E239 PolarHBondContact O-N 2.92Å
238	S	75.3	Confident	74.1	Confident	98 Å²	98	59.4 Å²	59.4	69%	0.685	36%	0.363	S	S	*	.	P	Polyproline II helix	trans	-56.4	128.9	179.8	-59.5	0	0	0	0	112.6	R103	R103-S238 VanDerWaalsContact NH2-CA 3.34Å
239	E	73.5	Confident	71.5	Confident	22 Å²	22	59.9 Å²	59.9	10%	0.103	37%	0.365	C	S	.	.	P	Polyproline II helix	trans	-86.8	134	174.9	-166	-177.3	174.1	0	0	109	G100 R101 R102 R103 Y166 I237	G100-E239 WeakPolarHBondContact CA-OE2 3.37Å; R101-E239 WeakPolarHBondContact CA-OE1 3.48Å; R101-E239 VanDerWaalsContact CB-OE1 3.3Å; R101-E239 WeakPolarHBondContact CB-OE1 3.35Å; R101-E239 PolarHBondContact N-OE1 3.08Å; R101-E239 PolarHBondContact N-OE2 2.91Å; R101-E239 VanDerWaalsContact N-OE2 3.13Å; R102-E239 WeakPolarHBondContact CG-OE1 3.3Å; R102-E239 PolarHBondContact N-OE1 2.65Å; R102-E239 PolarHBondContact N-OE2 2.74Å; R103-E239 PolarHBondContact N-OE2 3.31Å; Y166-E239 HydrophobicContact CE2-CB 3.93Å; Y166-E239 HydrophobicContact CE2-CG 4.14Å; I237-E239 PolarHBondContact O-N 2.92Å
240	A	62.5	Low	68.4	Low	64 Å²	64	64.8 Å²	64.8	53%	0.529	40%	0.396	S	S	.	.	P	Polyproline II helix	trans	-76	131.3	174.5	0	0	0	0	0	109.8
241	P	63.5	Low	65.7	Low	25 Å²	25	70.1 Å²	70.1	16%	0.162	43%	0.432	C	S	.	.	P	Polyproline II helix	trans	-68.6	140.4	178.9	26.6	-31.9	0	0	0	111.1	T243 E244	P241-T243 PolarHBondContact O-N 2.97Å; P241-E244 HydrophobicContact CG-CB 4.42Å; P241-E244 HydrophobicContact CG-CG 3.98Å; P241-E244 PolarHBondContact O-N 3.48Å
242	L	59.3	Low	62.9	Low	62 Å²	62	74.8 Å²	74.8	33%	0.325	45%	0.449	S	S	.	.	H	α-helix	trans	-50.7	-28.9	178.6	-77.9	172.7	0	0	0	113.8	C95 R101 E244 A246	C95-L242 WeakPolarHBondContact O-CD1 3.47Å; R101-L242 HydrophobicContact CB-CD1 4.41Å; R101-L242 HydrophobicContact CB-CG 4.38Å; R101-L242 HydrophobicContact CG-CD1 4.35Å; L242-E244 VanDerWaalsContact C-N 3.28Å; L242-E244 PolarHBondContact O-N 2.7Å; L242-A246 PolarHBondContact O-N 3.03Å
243	T	53.8	Low	60.1	Low	76 Å²	76	81.6 Å²	81.6	47%	0.466	48%	0.478	S	S	.	.	H	α-helix	trans	-68.5	-26.2	-178.4	-50	0	0	0	0	112.6	P241 K247	P241-T243 PolarHBondContact O-N 2.97Å; T243-K247 WeakPolarHBondContact O-CG 3.3Å
244	E	54.8	Low	57.2	Low	130 Å²	130	87.5 Å²	87.5	61%	0.607	51%	0.514	S	S	*	.	H	α-helix	trans	-82.1	-38.3	178.5	-73.4	-174	177.4	0	0	111.9	P241 L242 A246 K247 G248	P241-E244 HydrophobicContact CG-CB 4.42Å; P241-E244 HydrophobicContact CG-CG 3.98Å; P241-E244 PolarHBondContact O-N 3.48Å; L242-E244 VanDerWaalsContact C-N 3.28Å; L242-E244 PolarHBondContact O-N 2.7Å; E244-A246 VanDerWaalsContact C-N 3.31Å; E244-A246 PolarHBondContact O-N 3.32Å; E244-K247 PolarHBondContact O-N 2.63Å; E244-K247 VanDerWaalsContact O-N 3.1Å; E244-G248 PolarHBondContact O-N 2.93Å
245	V	56.4	Low	54.7	Low	90 Å²	90	92 Å²	92	55%	0.545	55%	0.546	S	S	.	.	H	α-helix	trans	-61.4	-42	175.9	-177.2	0	0	0	0	110.9	K247 G248	V245-K247 PolarHBondContact O-N 3.05Å; V245-G248 PolarHBondContact O-N 3.12Å
246	A	51.8	Low	52.2	Low	72 Å²	72	96.8 Å²	96.8	60%	0.595	56%	0.559	S	S	*	*	T	Hydrogen-bonded Turn	trans	-67	-21.4	177.5	0	0	0	0	0	113.9	L242 E244	L242-A246 PolarHBondContact O-N 3.03Å; E244-A246 VanDerWaalsContact C-N 3.31Å; E244-A246 PolarHBondContact O-N 3.32Å
247	K	47.9	Very low	49.8	Very low	170 Å²	170	103.7 Å²	103.7	74%	0.739	60%	0.595	S	S	*	*	T	Hydrogen-bonded Turn	trans	-87.9	-19	176.2	-74	179.9	180	-177.2	0	113.2	T243 E244 V245 I249	T243-K247 WeakPolarHBondContact O-CG 3.3Å; E244-K247 PolarHBondContact O-N 2.63Å; E244-K247 VanDerWaalsContact O-N 3.1Å; V245-K247 PolarHBondContact O-N 3.05Å; K247-I249 VanDerWaalsContact C-N 3.33Å
248	G	44.9	Very low	47.8	Very low	63 Å²	63	109.1 Å²	109.1	65%	0.649	63%	0.631	S	S	*	*	S	Bend	trans	-80.6	-7.3	-179.4	0	0	0	0	0	115.1	E244 V245 P250	E244-G248 PolarHBondContact O-N 2.93Å; V245-G248 PolarHBondContact O-N 3.12Å; G248-P250 WeakPolarHBondContact O-CD 3.17Å
249	I	40.4	Very low	46.1	Very low	123 Å²	123	110.6 Å²	110.6	63%	0.631	64%	0.638	S	S	*	*	S	Bend	trans	-94.9	111	179	-54.9	170.4	0	0	0	108.3	K247	K247-I249 VanDerWaalsContact C-N 3.33Å
250	P	31.7	Very low	44.3	Very low	105 Å²	105	117.8 Å²	117.8	68%	0.682	68%	0.676	S	S	*	*			trans	-61.9	139.9	171.4	-13.9	27.5	0	0	0	109.4	G248 Q252	G248-P250 WeakPolarHBondContact O-CD 3.17Å; P250-Q252 PolarHBondContact O-N 3.49Å; P250-Q252 VanDerWaalsContact O-N 3.08Å
251	P	37.2	Very low	42.8	Very low	124 Å²	124	120.2 Å²	120.2	81%	0.805	69%	0.689	S	S	*	*			trans	-60.8	117.1	174.9	24.1	-31.1	0	0	0	109.5	Q253	P251-Q253 PolarHBondContact O-N 2.98Å; P251-Q253 VanDerWaalsContact O-N 3.13Å
252	Q	37.2	Very low	41.4	Very low	172 Å²	172	124.8 Å²	124.8	80%	0.804	72%	0.722	S	S	*	*			trans	-59.5	113.8	178.8	-140.6	172.5	17.1	0	0	109.1	P250 T254	P250-Q252 PolarHBondContact O-N 3.49Å; P250-Q252 VanDerWaalsContact O-N 3.08Å; Q252-T254 PolarHBondContact O-N 3.41Å
253	Q	35.1	Very low	40.2	Very low	184 Å²	184	129.9 Å²	129.9	86%	0.86	75%	0.749	S	S	*	*	P	Polyproline II helix	trans	-70	123.5	173.1	-76.1	174	-32	0	0	109	P251	P251-Q253 PolarHBondContact O-N 2.98Å; P251-Q253 VanDerWaalsContact O-N 3.13Å
254	T	32.7	Very low	39.3	Very low	124 Å²	124	129.7 Å²	129.7	76%	0.761	76%	0.763	S	S	*	*	P	Polyproline II helix	trans	-50.8	138.2	167.3	28.2	0	0	0	0	111.2	Q252 Q256	Q252-T254 PolarHBondContact O-N 3.41Å; T254-Q256 PolarHBondContact O-N 3.28Å
255	P	37.2	Very low	37.9	Very low	128 Å²	128	131.6 Å²	131.6	83%	0.831	77%	0.774	S	S	*	*	P	Polyproline II helix	trans	-64.6	124.1	-178.1	-12.7	26.1	0	0	0	110.8
256	Q	36.7	Very low	36.8	Very low	191 Å²	191	138.9 Å²	138.9	89%	0.893	79%	0.793	S	S	*	*			trans	-106.7	131.2	160.5	-82.5	-177.8	-21.8	0	0	108	T254	T254-Q256 PolarHBondContact O-N 3.28Å
257	D	33.7	Very low	35.7	Very low	152 Å²	152	143.5 Å²	143.5	81%	0.813	80%	0.803	S	S	*	*	P	Polyproline II helix	trans	-56.5	149	-175.6	-60.9	-50.4	0	0	0	113.4
258	P	39	Very low	34.8	Very low	117 Å²	117	145.9 Å²	145.9	76%	0.76	81%	0.808	S	S	*	*	P	Polyproline II helix	trans	-74.9	142.8	-177.9	30.1	-32.2	0	0	0	111.9
259	P	37.9	Very low	34.2	Very low	129 Å²	129	145.6 Å²	145.6	84%	0.838	81%	0.805	S	S	*	*	P	Polyproline II helix	trans	-81.6	134	-173.1	31.8	-32.2	0	0	0	112.2
260	L	35.9	Very low	33.9	Very low	172 Å²	172	145.1 Å²	145.1	90%	0.901	81%	0.813	S	S	*	*	P	Polyproline II helix	trans	-73.7	134.3	169.8	-115.2	93.2	0	0	0	111
261	S	30.9	Very low	34	Very low	115 Å²	115	147.4 Å²	147.4	80%	0.804	82%	0.818	S	S	*	*	P	Polyproline II helix	trans	-62.4	137	174.4	50	0	0	0	0	114.1
262	S	35.5	Very low	33.9	Very low	122 Å²	122	149.8 Å²	149.8	85%	0.853	82%	0.818	S	S	*	*			trans	-147.8	126.9	151	-178.8	0	0	0	0	110.4
263	D	33	Very low	33.7	Very low	168 Å²	168	150.8 Å²	150.8	90%	0.898	82%	0.82	S	S	*	*			trans	-41.4	144.9	166.9	-104.3	-37.5	0	0	0	114.2
264	G	34.6	Very low	33.4	Very low	73 Å²	73	148.3 Å²	148.3	75%	0.753	82%	0.817	S	S	*	*			trans	168.4	72.2	174.5	0	0	0	0	0	114.4
265	M	26.7	Very low	33.4	Very low	170 Å²	170	151.6 Å²	151.6	84%	0.837	82%	0.821	S	S	*	*			trans	-58.8	121.5	169.4	169.2	171.3	140.5	0	0	112.4
266	Y	32.6	Very low	33	Very low	242 Å²	242	153 Å²	153	95%	0.949	82%	0.821	S	S	*	*			trans	-153.8	145.8	146.8	-80.8	-67.7	0	0	0	111.3
267	E	28.8	Very low	32.7	Very low	170 Å²	170	147.6 Å²	147.6	79%	0.794	82%	0.817	S	S	*	*			trans	-100.4	162.4	-156.1	-144.8	179.2	162.6	0	0	112.8
268	Y	29.2	Very low	32.6	Very low	219 Å²	219	151.6 Å²	151.6	86%	0.859	82%	0.823	S	S	*	*			trans	92.5	110.4	149	-132.1	-95.5	0	0	0	121.5
269	G	32.4	Very low	32.3	Very low	57 Å²	57	152.3 Å²	152.3	59%	0.588	82%	0.824	S	S	*	*				105.7	95.4	122.7	0	0	0	0	0	121.6
270	S	33.5	Very low	32.2	Very low	113 Å²	113	152.3 Å²	152.3	79%	0.79	82%	0.817	S	S	*	*			trans	75	117.1	135.2	54.6	0	0	0	0	124.6
271	I	34.3	Very low	32.5	Very low	153 Å²	153	149.5 Å²	149.5	79%	0.785	81%	0.809	S	S	*	*			trans	91.9	106.7	130.8	-61.2	168	0	0	0	121
272	E	34.2	Very low	33	Very low	174 Å²	174	152.3 Å²	152.3	81%	0.813	81%	0.81	S	S	*	*			trans	66.8	104.2	140.9	-68.9	-177	145.2	0	0	124.6
273	K	33.7	Very low	33.3	Very low	193 Å²	193	153.4 Å²	153.4	84%	0.839	81%	0.805	S	S	*	*			trans	46.1	108.5	130.1	-82.1	-176.2	175	173.6	0	123.2
274	V	29.2	Very low	33.6	Very low	132 Å²	132	149.1 Å²	149.1	80%	0.8	79%	0.793	S	S	*	*				59.4	111.3	121.3	-174.1	0	0	0	0	120.4
275	K	32.5	Very low	33.8	Very low	193 Å²	193	153.3 Å²	153.3	84%	0.839	80%	0.795	S	S	*	*			trans	-169.5	121.3	131.3	-116.2	175	180	176.3	0	115
276	N	28.6	Very low	34.5	Very low	157 Å²	157	152.4 Å²	152.4	84%	0.84	79%	0.789	S	S	*	*			trans	53.5	124.6	143.1	-68.2	-0.5	0	0	0	123.4
277	G	30.6	Very low	34.7	Very low	78 Å²	78	142.7 Å²	142.7	80%	0.804	76%	0.762	S	S	*	*			trans	-147.5	129.9	157	0	0	0	0	0	112.3
278	Y	31	Very low	35.3	Very low	237 Å²	237	137.1 Å²	137.1	93%	0.929	75%	0.745	S	S	*	*			trans	-68.3	149.2	-178.7	-92.6	-114.4	0	0	0	114.4
279	V	33.4	Very low	35.5	Very low	132 Å²	132	134.9 Å²	134.9	80%	0.8	74%	0.74	S	S	*	*			trans	-140.2	117.4	161.5	-175.4	0	0	0	0	113.7
280	N	36.5	Very low	35.8	Very low	129 Å²	129	138.1 Å²	138.1	69%	0.69	74%	0.744	S	S	*	*			trans	41.2	132.2	151.5	-65.3	-24.5	0	0	0	125.6
281	P	40.7	Very low	36	Very low	112 Å²	112	140 Å²	140	73%	0.727	74%	0.738	S	S	*	*	T	Hydrogen-bonded Turn	trans	-83.6	-3	-175.7	-7.3	27.1	0	0	0	118.2	L283 A284	P281-L283 PolarHBondContact O-N 3.36Å; P281-A284 WeakPolarHBondContact O-CB 3.24Å; P281-A284 PolarHBondContact O-N 2.98Å
282	E	42.3	Very low	35.9	Very low	174 Å²	174	137.9 Å²	137.9	81%	0.813	73%	0.728	S	S	*	*	T	Hydrogen-bonded Turn	trans	-71.3	-24.3	-175.8	-89.4	177.7	127.9	0	0	114.4	A284	E282-A284 PolarHBondContact O-N 3.01Å
283	L	41.6	Very low	35.9	Very low	145 Å²	145	136.2 Å²	136.2	76%	0.759	72%	0.72	S	S	*	*	H	α-helix	trans	-68.3	-21.1	174.7	-98.1	108.6	0	0	0	113.5	P281 M285	P281-L283 PolarHBondContact O-N 3.36Å; L283-M285 VanDerWaalsContact C-N 3.28Å; L283-M285 PolarHBondContact O-N 2.93Å
284	A	39.7	Very low	36	Very low	78 Å²	78	130.7 Å²	130.7	65%	0.645	71%	0.711	S	S	*	*	H	α-helix	trans	-69.5	-26	-177.9	0	0	0	0	0	112.8	P281 E282	P281-A284 WeakPolarHBondContact O-CB 3.24Å; P281-A284 PolarHBondContact O-N 2.98Å; E282-A284 PolarHBondContact O-N 3.01Å
285	M	39.2	Very low	36.2	Very low	161 Å²	161	129.2 Å²	129.2	79%	0.793	70%	0.695	S	S	*	*	H	α-helix	trans	-83.2	-26.7	-175.7	-130.9	179.1	71.4	0	0	113.4	L283	L283-M285 VanDerWaalsContact C-N 3.28Å; L283-M285 PolarHBondContact O-N 2.93Å
286	Q	40.1	Very low	36.2	Very low	151 Å²	151	126.2 Å²	126.2	71%	0.706	68%	0.684	S	S	*	*	H	α-helix	trans	-75.1	-31.2	173.6	-78.2	179.6	-19.9	0	0	112.4	A288 K289	Q286-A288 PolarHBondContact O-N 3.44Å; Q286-K289 PolarHBondContact O-N 2.92Å
287	G	38	Very low	36.7	Very low	38 Å²	38	124.5 Å²	124.5	39%	0.392	68%	0.679	S	S	.	*	H	α-helix	trans	-64	-22.3	174.4	0	0	0	0	0	114.4	K291	G287-K291 WeakPolarHBondContact O-CG 3.26Å
288	A	40.3	Very low	37	Very low	53 Å²	53	130 Å²	130	44%	0.438	68%	0.676	S	S	.	*	H	α-helix	trans	-76.1	-31.5	177.3	0	0	0	0	0	112.9	Q286	Q286-A288 PolarHBondContact O-N 3.44Å
289	K	34.4	Very low	37.7	Very low	172 Å²	172	128.5 Å²	128.5	75%	0.748	67%	0.668	S	S	*	*	H	α-helix	trans	-71.4	-33.9	178.1	-104.8	-179.2	175	179.6	0	112.7	Q286	Q286-K289 PolarHBondContact O-N 2.92Å
290	N	39	Very low	38.3	Very low	126 Å²	126	125.6 Å²	125.6	67%	0.674	66%	0.658	S	S	*	*	H	α-helix	trans	-76.1	-23.6	177.1	-81.4	-2.4	0	0	0	113.8	N292 H293	N290-N292 VanDerWaalsContact C-N 3.31Å; N290-N292 PolarHBondContact O-N 3.05Å; N290-H293 PolarHBondContact O-N 3.49Å
291	K	37	Very low	39.3	Very low	153 Å²	153	120.5 Å²	120.5	67%	0.665	63%	0.63	S	S	*	*	H	α-helix	trans	-67.5	-31.1	175.6	-77.9	178.9	178.4	179.5	0	113	G287 H293 A294 E295	G287-K291 WeakPolarHBondContact O-CG 3.26Å; K291-H293 VanDerWaalsContact C-N 3.31Å; K291-H293 PolarHBondContact O-N 3.24Å; K291-A294 PolarHBondContact O-N 2.84Å; K291-E295 PolarHBondContact O-N 3.31Å
292	N	31.7	Very low	40.2	Very low	107 Å²	107	119.4 Å²	119.4	57%	0.572	62%	0.622	S	S	*	*	H	α-helix	trans	-69.8	-27.9	179.4	-69.3	-6.4	0	0	0	112.8	N290	N290-N292 VanDerWaalsContact C-N 3.31Å; N290-N292 PolarHBondContact O-N 3.05Å
293	H	33.5	Very low	41.3	Very low	139 Å²	139	114.6 Å²	114.6	64%	0.644	60%	0.601	S	S	*	*	H	α-helix	trans	-75	-35.2	174.8	-100.8	-60.5	0	0	0	112.8	N290 K291 E295 Q296	N290-H293 PolarHBondContact O-N 3.49Å; K291-H293 VanDerWaalsContact C-N 3.31Å; K291-H293 PolarHBondContact O-N 3.24Å; H293-E295 VanDerWaalsContact C-N 3.34Å; H293-E295 PolarHBondContact O-N 3.4Å; H293-Q296 PolarHBondContact O-N 3.36Å
294	A	36.2	Very low	42.5	Very low	78 Å²	78	114.6 Å²	114.6	65%	0.645	60%	0.595	S	S	*	*	H	α-helix	trans	-71.5	-25.5	176.4	0	0	0	0	0	113.3	K291	K291-A294 PolarHBondContact O-N 2.84Å
295	E	34.5	Very low	43.7	Very low	100 Å²	100	112.4 Å²	112.4	47%	0.467	58%	0.575	S	S	.	*	H	α-helix	trans	-79.6	-16	173	-77.9	-165.9	131.6	0	0	113.6	K291 H293 T297 R298	K291-E295 PolarHBondContact O-N 3.31Å; H293-E295 VanDerWaalsContact C-N 3.34Å; H293-E295 PolarHBondContact O-N 3.4Å; E295-T297 PolarHBondContact O-N 2.88Å; E295-R298 VanDerWaalsContact O-CB 3.25Å; E295-R298 WeakPolarHBondContact O-CB 3.39Å; E295-R298 PolarHBondContact O-N 2.87Å; E295-R298 IonicContact OE1-CZ 3.07Å; E295-R298 IonicContact OE1-NH1 3.01Å; E295-R298 PolarHBondContact OE1-NH1 3.3Å; E295-R298 IonicContact OE1-NH2 3.63Å
296	Q	32.9	Very low	45	Very low	131 Å²	131	105 Å²	105	61%	0.612	54%	0.539	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75.8	-12.2	-176.3	-157.2	154.1	-4.3	0	0	113.6	H293 R298	H293-Q296 PolarHBondContact O-N 3.36Å; Q296-R298 PolarHBondContact O-N 3.45Å
297	T	38.3	Very low	46.4	Very low	120 Å²	120	102.5 Å²	102.5	74%	0.736	53%	0.529	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.4	4.1	172.2	-37.6	0	0	0	0	112.8	E295 R299	E295-T297 PolarHBondContact O-N 2.88Å; T297-R299 VanDerWaalsContact C-N 3.27Å; T297-R299 PolarHBondContact O-N 3.07Å
298	R	37.4	Very low	48	Very low	194 Å²	194	107.4 Å²	107.4	73%	0.732	54%	0.536	S	S	*	.			trans	-74.6	6.5	177.1	-88	-177.2	163.4	159	3	116.2	E295 Q296 A300	E295-R298 VanDerWaalsContact O-CB 3.25Å; E295-R298 WeakPolarHBondContact O-CB 3.39Å; E295-R298 PolarHBondContact O-N 2.87Å; E295-R298 IonicContact OE1-CZ 3.07Å; E295-R298 IonicContact OE1-NH1 3.01Å; E295-R298 PolarHBondContact OE1-NH1 3.3Å; E295-R298 IonicContact OE1-NH2 3.63Å; Q296-R298 PolarHBondContact O-N 3.45Å; R298-A300 PolarHBondContact O-N 2.69Å
299	R	44.4	Very low	49.3	Very low	206 Å²	206	105.9 Å²	105.9	78%	0.777	52%	0.524	S	S	*	.			trans	-74.8	104.7	-173.4	-89.4	-178.5	174.2	166.9	-0.3	111.6	T297 M301	T297-R299 VanDerWaalsContact C-N 3.27Å; T297-R299 PolarHBondContact O-N 3.07Å; R299-M301 PolarHBondContact O-N 2.68Å
300	A	47.5	Very low	51.1	Low	71 Å²	71	99.8 Å²	99.8	59%	0.587	50%	0.499	S	S	*	.			trans	-38.3	124.5	156.5	0	0	0	0	0	109.3	R298 T302	R298-A300 PolarHBondContact O-N 2.69Å; A300-T302 PolarHBondContact O-N 3.37Å
301	M	55.9	Low	52.9	Low	21 Å²	21	98.2 Å²	98.2	10%	0.103	49%	0.494	C	S	.	.			trans	-65.6	96.1	-178.5	-84.8	-151.5	-75.6	0	0	110.4	V87 R299 S305 M474	V87-M301 WeakPolarHBondContact CG2-O 3.27Å; R299-M301 PolarHBondContact O-N 2.68Å; M301-S305 WeakPolarHBondContact CA-OG 3.38Å; M301-S305 WeakPolarHBondContact CB-OG 3.47Å; M301-S305 VanDerWaalsContact CG-OG 3.28Å; M301-S305 WeakPolarHBondContact CG-OG 3.39Å; M301-M474 HydrophobicContact CE-CE 3.94Å; M301-M474 HydrophobicContact CE-CG 4.18Å; M301-M474 HydrophobicContact SD-CE 3.59Å; M301-M474 VanDerWaalsContact SD-CE 3.59Å; M301-M474 HydrophobicContact SD-CG 4.38Å; M301-M474 HydrophobicContact SD-SD 4.16Å
302	T	61.6	Low	54.7	Low	89 Å²	89	96.4 Å²	96.4	55%	0.546	49%	0.491	S	S	.	.			trans	-67.1	157.8	167.2	48.1	0	0	0	0	111	A300 K304 S305 L306	A300-T302 PolarHBondContact O-N 3.37Å; T302-K304 PolarHBondContact O-N 3.39Å; T302-S305 PolarHBondContact N-OG 2.96Å; T302-S305 WeakPolarHBondContact O-CA 3.32Å; T302-S305 WeakPolarHBondContact O-CB 3.47Å; T302-S305 PolarHBondContact O-N 3.46Å; T302-S305 PolarHBondContact O-OG 3.36Å; T302-L306 PolarHBondContact O-N 3.3Å
303	L	63.4	Low	56.8	Low	74 Å²	74	91.5 Å²	91.5	39%	0.387	47%	0.465	S	S	.	.	H	α-helix	trans	-45.2	-32.9	172.4	-175.7	67.2	0	0	0	113.7	F82 L83 S305 L306 L307	F82-L303 HydrophobicContact CE1-CD1 4.18Å; L83-L303 HydrophobicContact CD2-CD1 4.26Å; L83-L303 HydrophobicContact CD2-CD2 4.22Å; L303-S305 VanDerWaalsContact C-N 3.33Å; L303-S305 PolarHBondContact O-N 2.91Å; L303-L306 WeakPolarHBondContact O-CB 3.5Å; L303-L306 PolarHBondContact O-N 3.11Å; L303-L307 HydrophobicContact CG-CD1 4.45Å; L303-L307 PolarHBondContact O-N 2.92Å
304	K	68.1	Low	59.2	Low	145 Å²	145	86.7 Å²	86.7	63%	0.63	45%	0.447	S	S	*	.	H	α-helix	trans	-62	-34.8	174.8	-169.5	172.6	-175.4	171.3	0	113.6	T302 R308	T302-K304 PolarHBondContact O-N 3.39Å; K304-R308 WeakPolarHBondContact O-CB 2.93Å; K304-R308 PolarHBondContact O-N 2.96Å
305	S	64	Low	61.5	Low	32 Å²	32	86.7 Å²	86.7	22%	0.224	44%	0.44	C	S	.	.	H	α-helix	trans	-73.6	-34.4	176	68.3	0	0	0	0	111.7	M301 T302 L303 R308 A309	M301-S305 WeakPolarHBondContact CA-OG 3.38Å; M301-S305 WeakPolarHBondContact CB-OG 3.47Å; M301-S305 VanDerWaalsContact CG-OG 3.28Å; M301-S305 WeakPolarHBondContact CG-OG 3.39Å; T302-S305 PolarHBondContact N-OG 2.96Å; T302-S305 WeakPolarHBondContact O-CA 3.32Å; T302-S305 WeakPolarHBondContact O-CB 3.47Å; T302-S305 PolarHBondContact O-N 3.46Å; T302-S305 PolarHBondContact O-OG 3.36Å; L303-S305 VanDerWaalsContact C-N 3.33Å; L303-S305 PolarHBondContact O-N 2.91Å; S305-R308 CarbonylContact O-C 3.6Å; S305-R308 PolarHBondContact O-N 3.18Å; S305-A309 VanDerWaalsContact O-CB 3.23Å; S305-A309 WeakPolarHBondContact O-CB 3.27Å; S305-A309 PolarHBondContact O-N 3.3Å
306	L	66.2	Low	63.9	Low	6 Å²	6	83.6 Å²	83.6	3%	0.031	43%	0.425	C	S	.	.	H	α-helix	trans	-60.4	-53.7	171.3	-106.3	-156.3	0	0	0	111.8	P86 T302 L303 R308 A309 L310	P86-L306 HydrophobicContact CB-CD1 4.02Å; P86-L306 HydrophobicContact CB-CD2 3.89Å; P86-L306 HydrophobicContact CB-CG 3.55Å; P86-L306 HydrophobicContact CG-CB 4.49Å; P86-L306 HydrophobicContact CG-CD1 3.04Å; P86-L306 HydrophobicContact CG-CD2 3.71Å; P86-L306 HydrophobicContact CG-CG 3.17Å; T302-L306 PolarHBondContact O-N 3.3Å; L303-L306 WeakPolarHBondContact O-CB 3.5Å; L303-L306 PolarHBondContact O-N 3.11Å; L306-R308 PolarHBondContact O-N 3.41Å; L306-A309 WeakPolarHBondContact O-CA 3.4Å; L306-A309 WeakPolarHBondContact O-CB 3.3Å; L306-A309 PolarHBondContact O-N 2.89Å; L306-L310 PolarHBondContact O-N 3.35Å
307	L	70.8	Confident	66.4	Low	97 Å²	97	77.5 Å²	77.5	51%	0.508	40%	0.397	S	S	.	.	H	α-helix	trans	-59.6	-40.9	179.5	-72.4	170.3	0	0	0	110.1	L303 L310 V311	L303-L307 HydrophobicContact CG-CD1 4.45Å; L303-L307 PolarHBondContact O-N 2.92Å; L307-L310 PolarHBondContact O-N 2.89Å; L307-V311 WeakPolarHBondContact O-CB 3.47Å; L307-V311 WeakPolarHBondContact O-CG2 3.37Å; L307-V311 PolarHBondContact O-N 2.91Å
308	R	71.6	Confident	68.8	Low	141 Å²	141	76.3 Å²	76.3	53%	0.532	38%	0.379	S	S	.	.	H	α-helix	trans	-64.8	-39.6	173.8	-173.7	-179.7	-66.3	176.9	-6.9	112.4	K304 S305 L306 V311 N312	K304-R308 WeakPolarHBondContact O-CB 2.93Å; K304-R308 PolarHBondContact O-N 2.96Å; S305-R308 CarbonylContact O-C 3.6Å; S305-R308 PolarHBondContact O-N 3.18Å; L306-R308 PolarHBondContact O-N 3.41Å; R308-V311 PolarHBondContact O-N 3.45Å; R308-N312 WeakPolarHBondContact CG-ND2 3.37Å; R308-N312 WeakPolarHBondContact O-CB 3.45Å; R308-N312 PolarHBondContact O-N 3.33Å
309	A	68.3	Low	71.4	Confident	22 Å²	22	71.2 Å²	71.2	18%	0.182	36%	0.36	C	S	.	.	H	α-helix	trans	-64.1	-46.1	177.5	0	0	0	0	0	110.5	S305 L306 V311 N312 M313 M474	S305-A309 VanDerWaalsContact O-CB 3.23Å; S305-A309 WeakPolarHBondContact O-CB 3.27Å; S305-A309 PolarHBondContact O-N 3.3Å; L306-A309 WeakPolarHBondContact O-CA 3.4Å; L306-A309 WeakPolarHBondContact O-CB 3.3Å; L306-A309 PolarHBondContact O-N 2.89Å; A309-V311 VanDerWaalsContact C-N 3.34Å; A309-V311 PolarHBondContact O-N 2.9Å; A309-N312 CarbonylContact O-C 3.6Å; A309-N312 PolarHBondContact O-N 3.46Å; A309-M313 WeakPolarHBondContact O-CA 3.29Å; A309-M313 VanDerWaalsContact O-CB 3.22Å; A309-M313 WeakPolarHBondContact O-CB 3.37Å; A309-M313 PolarHBondContact O-N 2.92Å; A309-M474 HydrophobicContact CB-SD 4.1Å
310	L	71.8	Confident	73.6	Confident	43 Å²	43	61.5 Å²	61.5	23%	0.225	32%	0.323	C	S	.	.	H	α-helix	trans	-58.6	-44.4	173.5	-73.9	169.1	0	0	0	112.3	L306 L307 N312 R318 T478 M482	L306-L310 PolarHBondContact O-N 3.35Å; L307-L310 PolarHBondContact O-N 2.89Å; L310-N312 VanDerWaalsContact C-N 3.33Å; L310-N312 PolarHBondContact O-N 3.24Å; L310-R318 PolarHBondContact O-NE 3.45Å; L310-T478 HydrophobicContact CD2-CG2 3.34Å; L310-T478 HydrophobicContact CG-CG2 4.07Å; L310-M482 HydrophobicContact CD1-CE 4.11Å; L310-M482 HydrophobicContact CD2-CE 3.57Å; L310-M482 HydrophobicContact CG-CE 4.46Å
311	V	76	Confident	75.7	Confident	94 Å²	94	58.4 Å²	58.4	57%	0.57	30%	0.297	S	S	*	.	H	α-helix	trans	-73.8	-22.1	-179.7	172	0	0	0	0	113	L307 R308 A309 R318	L307-V311 WeakPolarHBondContact O-CB 3.47Å; L307-V311 WeakPolarHBondContact O-CG2 3.37Å; L307-V311 PolarHBondContact O-N 2.91Å; R308-V311 PolarHBondContact O-N 3.45Å; A309-V311 VanDerWaalsContact C-N 3.34Å; A309-V311 PolarHBondContact O-N 2.9Å; V311-R318 PolarHBondContact O-NH1 3.38Å; V311-R318 PolarHBondContact O-NH2 2.9Å
312	N	74.6	Confident	77.5	Confident	114 Å²	114	60.9 Å²	60.9	61%	0.61	31%	0.311	S	S	*	.	H	α-helix	trans	-102.6	-8.3	179.2	-68.8	-7.3	0	0	0	113.4	R308 A309 L310	R308-N312 WeakPolarHBondContact CG-ND2 3.37Å; R308-N312 WeakPolarHBondContact O-CB 3.45Å; R308-N312 PolarHBondContact O-N 3.33Å; A309-N312 CarbonylContact O-C 3.6Å; A309-N312 PolarHBondContact O-N 3.46Å; L310-N312 VanDerWaalsContact C-N 3.33Å; L310-N312 PolarHBondContact O-N 3.24Å
313	M	76.8	Confident	79.1	Confident	5 Å²	5	56.7 Å²	56.7	3%	0.025	29%	0.285	C	S	.	.	S	Bend	trans	-59.1	142.9	-178.4	175.3	173	-84.6	0	0	110.9	A309 Y317 R318 T478	A309-M313 WeakPolarHBondContact O-CA 3.29Å; A309-M313 VanDerWaalsContact O-CB 3.22Å; A309-M313 WeakPolarHBondContact O-CB 3.37Å; A309-M313 PolarHBondContact O-N 2.92Å; M313-Y317 HydrophobicContact CG-CG 4.38Å; M313-Y317 WeakPolarHBondContact SD-CB 3.35Å; M313-R318 HydrophobicContact CB-CG 3.75Å; M313-R318 HydrophobicContact CG-CG 3.78Å; M313-R318 PolarHBondContact O-NE 2.96Å; M313-R318 PolarHBondContact O-NH2 2.91Å; M313-R318 HydrophobicContact SD-CG 4.12Å; M313-T478 HydrophobicContact CE-CG2 3.88Å
314	P	82.4	Confident	80.5	Confident	38 Å²	38	53.2 Å²	53.2	25%	0.247	27%	0.266	C	S	.	.			trans	-60.4	152.6	175	-22.7	33.2	0	0	0	111.9	H316 Y317 R318	P314-H316 VanDerWaalsContact C-N 3.3Å; P314-H316 WeakPolarHBondContact CB-CE1 3.3Å; P314-H316 WeakPolarHBondContact CB-ND1 3.42Å; P314-H316 PolarHBondContact O-N 3.4Å; P314-Y317 HydrophobicContact CB-CD2 4.05Å; P314-Y317 HydrophobicContact CG-CD2 4Å; P314-Y317 HydrophobicContact CG-CE2 4.35Å; P314-Y317 PolarHBondContact O-N 2.92Å; P314-R318 PolarHBondContact O-N 3.32Å; P314-R318 VanDerWaalsContact O-N 3.11Å
315	P	85	Confident	81.8	Confident	78 Å²	78	47.8 Å²	47.8	51%	0.506	24%	0.244	S	C	.	.	H	α-helix	trans	-54.1	-41.4	-174.2	-27.1	34.6	0	0	0	114	Y317 R318 Y319	P315-Y317 PolarHBondContact O-N 3.18Å; P315-R318 PolarHBondContact O-N 2.8Å; P315-R318 VanDerWaalsContact O-N 3.16Å; P315-Y319 HydrophobicContact CB-CD2 4.45Å; P315-Y319 HydrophobicContact CB-CE2 3.87Å; P315-Y319 WeakPolarHBondContact O-CD2 3.09Å; P315-Y319 VanDerWaalsContact O-CG 3.27Å; P315-Y319 PolarHBondContact O-N 3.32Å
316	H	84.5	Confident	83.3	Confident	35 Å²	35	47.7 Å²	47.7	16%	0.162	24%	0.241	C	C	.	.	H	α-helix	trans	-62	-40.7	-179.3	52.1	-71.5	0	0	0	113.2	P314 L320 Y449 E453	P314-H316 VanDerWaalsContact C-N 3.3Å; P314-H316 WeakPolarHBondContact CB-CE1 3.3Å; P314-H316 WeakPolarHBondContact CB-ND1 3.42Å; P314-H316 PolarHBondContact O-N 3.4Å; H316-L320 PolarHBondContact O-N 3.42Å; H316-L320 VanDerWaalsContact O-N 3.11Å; H316-Y449 HydrophobicContact CB-CE2 4.39Å; H316-Y449 AromaticContact CD2-CD2 3.81Å; H316-Y449 AromaticContact CD2-CG 3.85Å; H316-E453 IonicContact CE1-OE1 3.6Å; H316-E453 PolarHBondContact CE1-OE1 3.5Å; H316-E453 IonicContact NE2-OE1 3.73Å; H316-E453 PolarHBondContact NE2-OE1 3.41Å; H316-E453 VanDerWaalsContact NE2-OE1 3.16Å
317	Y	86	Confident	84.7	Confident	2 Å²	2	47.4 Å²	47.4	1%	0.008	24%	0.239	C	C	.	.	H	α-helix	trans	-72.4	-33.9	174.7	-67.8	-88.5	0	0	0	112.4	M313 P314 P315 L320 C321 I446 Y449 H450 E453	M313-Y317 HydrophobicContact CG-CG 4.38Å; M313-Y317 WeakPolarHBondContact SD-CB 3.35Å; P314-Y317 HydrophobicContact CB-CD2 4.05Å; P314-Y317 HydrophobicContact CG-CD2 4Å; P314-Y317 HydrophobicContact CG-CE2 4.35Å; P314-Y317 PolarHBondContact O-N 2.92Å; P315-Y317 PolarHBondContact O-N 3.18Å; Y317-L320 WeakPolarHBondContact O-CB 3.39Å; Y317-L320 PolarHBondContact O-N 2.84Å; Y317-C321 PolarHBondContact O-N 3.38Å; Y317-C321 PolarHBondContact O-SG 3.02Å; Y317-I446 HydrophobicContact CD1-CG1 4.45Å; Y317-I446 HydrophobicContact CE1-CG2 4.48Å; Y317-Y449 HydrophobicContact CD1-CD2 4.11Å; Y317-Y449 HydrophobicContact CE1-CD2 4.03Å; Y317-Y449 HydrophobicContact CE1-CG 4.45Å; Y317-Y449 HydrophobicContact CG-CD2 4.5Å; Y317-Y449 WeakPolarHBondContact OH-CB 3.09Å; Y317-H450 PolarHBondContact OH-N 3.36Å; Y317-H450 PolarHBondContact OH-ND1 2.93Å; Y317-E453 VanDerWaalsContact CE2-OE1 3.29Å; Y317-E453 WeakPolarHBondContact CE2-OE1 3.42Å; Y317-E453 PolarHBondContact OH-OE2 2.82Å
318	R	88.1	Confident	85.9	Confident	96 Å²	96	43.3 Å²	43.3	36%	0.362	22%	0.217	S	C	.	.	H	α-helix	trans	-64	-46.3	175.3	-68.4	-170.4	-154.8	174.2	12.7	111.3	L310 V311 M313 P314 P315 L320 C321 I322	L310-R318 PolarHBondContact O-NE 3.45Å; V311-R318 PolarHBondContact O-NH1 3.38Å; V311-R318 PolarHBondContact O-NH2 2.9Å; M313-R318 HydrophobicContact CB-CG 3.75Å; M313-R318 HydrophobicContact CG-CG 3.78Å; M313-R318 PolarHBondContact O-NE 2.96Å; M313-R318 PolarHBondContact O-NH2 2.91Å; M313-R318 HydrophobicContact SD-CG 4.12Å; P314-R318 PolarHBondContact O-N 3.32Å; P314-R318 VanDerWaalsContact O-N 3.11Å; P315-R318 PolarHBondContact O-N 2.8Å; P315-R318 VanDerWaalsContact O-N 3.16Å; R318-L320 PolarHBondContact O-N 3.43Å; R318-C321 PolarHBondContact O-N 3.22Å; R318-C321 VanDerWaalsContact O-N 3.16Å; R318-I322 WeakPolarHBondContact O-CG1 3.46Å; R318-I322 PolarHBondContact O-N 2.87Å
319	Y	91.8	Very high	87	Confident	86 Å²	86	37.9 Å²	37.9	34%	0.337	20%	0.2	S	C	.	.	H	α-helix	trans	-60.2	-39.3	175.9	-61.7	-43	0	0	0	111	P315 I322 S323 F521 F525	P315-Y319 HydrophobicContact CB-CD2 4.45Å; P315-Y319 HydrophobicContact CB-CE2 3.87Å; P315-Y319 WeakPolarHBondContact O-CD2 3.09Å; P315-Y319 VanDerWaalsContact O-CG 3.27Å; P315-Y319 PolarHBondContact O-N 3.32Å; Y319-I322 PolarHBondContact O-N 3.3Å; Y319-S323 WeakPolarHBondContact O-CB 3.17Å; Y319-S323 PolarHBondContact O-N 3.19Å; Y319-S323 PolarHBondContact O-OG 3.28Å; Y319-F521 AromaticContact CD1-CZ 4Å; Y319-F521 HydrophobicContact CD1-CZ 4Å; Y319-F521 WeakPolarHBondContact O-CE1 3.32Å; Y319-F525 HydrophobicContact CD1-CB 4.05Å; Y319-F525 HydrophobicContact CD1-CD1 4.27Å; Y319-F525 HydrophobicContact CD1-CG 4.31Å; Y319-F525 HydrophobicContact CD2-CB 4.18Å; Y319-F525 HydrophobicContact CE1-CD1 4.01Å; Y319-F525 HydrophobicContact CE1-CG 4.49Å; Y319-F525 HydrophobicContact CE2-CD1 4.44Å; Y319-F525 HydrophobicContact CG-CB 3.83Å
320	L	92.2	Very high	88.2	Confident	2 Å²	2	36.8 Å²	36.8	1%	0.01	19%	0.191	C	C	.	.	H	α-helix	trans	-61.5	-46.3	173.7	-170.4	61.9	0	0	0	112.1	H316 Y317 R318 I322 S323 H324 Y401 P442 L445 I446 Y449	H316-L320 PolarHBondContact O-N 3.42Å; H316-L320 VanDerWaalsContact O-N 3.11Å; Y317-L320 WeakPolarHBondContact O-CB 3.39Å; Y317-L320 PolarHBondContact O-N 2.84Å; R318-L320 PolarHBondContact O-N 3.43Å; L320-I322 PolarHBondContact O-N 3.49Å; L320-S323 WeakPolarHBondContact CA-OG 3.36Å; L320-S323 PolarHBondContact O-N 2.92Å; L320-S323 PolarHBondContact O-OG 3.32Å; L320-H324 WeakPolarHBondContact O-CB 3.44Å; L320-H324 PolarHBondContact O-N 3.44Å; L320-Y401 HydrophobicContact CD1-CE1 4.2Å; L320-P442 HydrophobicContact CD1-CB 4.24Å; L320-L445 HydrophobicContact CD1-CB 4.23Å; L320-L445 HydrophobicContact CD1-CD1 3.63Å; L320-L445 HydrophobicContact CD2-CB 3.9Å; L320-I446 HydrophobicContact CD2-CD1 4.36Å; L320-I446 HydrophobicContact CD2-CG1 3.58Å; L320-Y449 HydrophobicContact CB-CE2 4.45Å; L320-Y449 HydrophobicContact CD2-CD2 4.34Å; L320-Y449 HydrophobicContact CD2-CE2 3.95Å
321	C	91.4	Very high	89.3	Confident	6 Å²	6	35.3 Å²	35.3	4%	0.041	18%	0.183	C	C	.	.	H	α-helix	trans	-61.8	-43.6	177	-66.5	0	0	0	0	112.5	Y317 R318 H324 L325 M482	Y317-C321 PolarHBondContact O-N 3.38Å; Y317-C321 PolarHBondContact O-SG 3.02Å; R318-C321 PolarHBondContact O-N 3.22Å; R318-C321 VanDerWaalsContact O-N 3.16Å; C321-H324 PolarHBondContact O-N 3.01Å; C321-L325 WeakPolarHBondContact O-CB 2.94Å; C321-L325 PolarHBondContact O-N 2.74Å; C321-M482 HydrophobicContact CB-CG 4Å; C321-M482 HydrophobicContact CB-SD 4.21Å
322	I	93.1	Very high	90	Very high	74 Å²	74	31.8 Å²	31.8	38%	0.379	16%	0.161	S	C	.	.	H	α-helix	trans	-63.4	-46.3	177.2	-67	165.7	0	0	0	110.3	R318 Y319 L320 H324 L325 I326 F521	R318-I322 WeakPolarHBondContact O-CG1 3.46Å; R318-I322 PolarHBondContact O-N 2.87Å; Y319-I322 PolarHBondContact O-N 3.3Å; L320-I322 PolarHBondContact O-N 3.49Å; I322-H324 VanDerWaalsContact C-N 3.31Å; I322-H324 PolarHBondContact O-N 3.03Å; I322-L325 WeakPolarHBondContact O-CB 2.97Å; I322-L325 PolarHBondContact O-N 3.33Å; I322-I326 HydrophobicContact CG2-CD1 3.89Å; I322-I326 VanDerWaalsContact O-CG1 3.3Å; I322-I326 WeakPolarHBondContact O-CG1 3.08Å; I322-I326 PolarHBondContact O-N 2.92Å; I322-F521 HydrophobicContact CB-CE1 4.17Å; I322-F521 HydrophobicContact CB-CZ 3.88Å; I322-F521 HydrophobicContact CD1-CZ 4.42Å; I322-F521 HydrophobicContact CG2-CE1 4Å; I322-F521 HydrophobicContact CG2-CE2 3.84Å; I322-F521 HydrophobicContact CG2-CZ 3.51Å
323	S	94.3	Very high	90.7	Very high	0 Å²	0	26.5 Å²	26.5	0%	0	13%	0.132	C	C	.	.	H	α-helix	trans	-58.9	-46.4	175.7	68.3	0	0	0	0	110.3	Y319 L320 L325 I326 G327 Y401 Y405	Y319-S323 WeakPolarHBondContact O-CB 3.17Å; Y319-S323 PolarHBondContact O-N 3.19Å; Y319-S323 PolarHBondContact O-OG 3.28Å; L320-S323 WeakPolarHBondContact CA-OG 3.36Å; L320-S323 PolarHBondContact O-N 2.92Å; L320-S323 PolarHBondContact O-OG 3.32Å; S323-L325 VanDerWaalsContact C-N 3.34Å; S323-L325 PolarHBondContact O-N 3.46Å; S323-I326 WeakPolarHBondContact O-CB 3.36Å; S323-I326 PolarHBondContact O-N 3.39Å; S323-I326 VanDerWaalsContact O-N 3.12Å; S323-G327 PolarHBondContact O-N 2.95Å; S323-Y401 WeakPolarHBondContact OG-CE1 3.24Å; S323-Y405 PolarHBondContact O-OH 3.3Å
324	H	93.9	Very high	91.4	Very high	1 Å²	1	26.3 Å²	26.3	1%	0.005	13%	0.131	C	C	.	.	H	α-helix	trans	-59.6	-42.7	178.8	-160.7	64	0	0	0	113.1	L320 C321 I322 G327 W328 Y401 L438 P442 L479	L320-H324 WeakPolarHBondContact O-CB 3.44Å; L320-H324 PolarHBondContact O-N 3.44Å; C321-H324 PolarHBondContact O-N 3.01Å; I322-H324 VanDerWaalsContact C-N 3.31Å; I322-H324 PolarHBondContact O-N 3.03Å; H324-G327 PolarHBondContact O-N 2.93Å; H324-W328 AromaticContact CD2-CD1 3.54Å; H324-W328 AromaticContact CD2-NE1 3.68Å; H324-W328 AromaticContact CE1-CD1 3.52Å; H324-W328 AromaticContact CE1-NE1 3.01Å; H324-W328 PolarHBondContact CE1-NE1 3.43Å; H324-W328 AromaticContact CG-CD1 3.83Å; H324-W328 AromaticContact ND1-CD1 3.78Å; H324-W328 AromaticContact ND1-NE1 3.7Å; H324-W328 AromaticContact NE2-CD1 3.35Å; H324-W328 VanDerWaalsContact NE2-CD1 3.35Å; H324-W328 AromaticContact NE2-NE1 2.95Å; H324-W328 PolarHBondContact NE2-NE1 2.98Å; H324-W328 VanDerWaalsContact O-CD1 3.3Å; H324-W328 PolarHBondContact O-N 2.85Å; H324-Y401 WeakPolarHBondContact CA-OH 3.37Å; H324-Y401 PolarHBondContact N-OH 3.2Å; H324-L438 PolarHBondContact CE1-O 2.97Å; H324-P442 VanDerWaalsContact ND1-CG 3.33Å; H324-P442 WeakPolarHBondContact ND1-CG 3.35Å; H324-L479 HydrophobicContact CB-CD1 3.55Å; H324-L479 VanDerWaalsContact CD2-CD1 3.47Å; H324-L479 WeakPolarHBondContact CD2-CD1 3.35Å; H324-L479 PolarHBondContact CD2-O 3.5Å; H324-L479 VanDerWaalsContact CG-CD1 3.49Å
325	L	94.8	Very high	91.6	Very high	32 Å²	32	25.8 Å²	25.8	17%	0.168	13%	0.126	C	C	.	.	H	α-helix	trans	-58.3	-47.5	174.1	177.5	64.1	0	0	0	111.6	C321 I322 S323 G327 T329 M482 L485 A486 L489	C321-L325 WeakPolarHBondContact O-CB 2.94Å; C321-L325 PolarHBondContact O-N 2.74Å; I322-L325 WeakPolarHBondContact O-CB 2.97Å; I322-L325 PolarHBondContact O-N 3.33Å; S323-L325 VanDerWaalsContact C-N 3.34Å; S323-L325 PolarHBondContact O-N 3.46Å; L325-G327 VanDerWaalsContact C-N 3.34Å; L325-G327 PolarHBondContact O-N 3.22Å; L325-T329 VanDerWaalsContact O-CB 3.31Å; L325-T329 WeakPolarHBondContact O-CB 3.47Å; L325-T329 PolarHBondContact O-N 3.24Å; L325-T329 PolarHBondContact O-OG1 3.43Å; L325-M482 HydrophobicContact CB-CB 4.15Å; L325-M482 HydrophobicContact CB-SD 4.4Å; L325-M482 VanDerWaalsContact CD1-O 3.27Å; L325-M482 WeakPolarHBondContact CD1-O 3.43Å; L325-L485 HydrophobicContact CD1-CB 3.88Å; L325-L485 HydrophobicContact CD1-CD2 3.91Å; L325-L485 HydrophobicContact CD1-CG 3.8Å; L325-L485 HydrophobicContact CD2-CD2 3.9Å; L325-A486 HydrophobicContact CD1-CB 4.03Å; L325-L489 HydrophobicContact CD1-CD1 4.21Å
326	I	96	Very high	91.4	Very high	29 Å²	29	25.5 Å²	25.5	15%	0.149	12%	0.12	C	C	.	.	H	α-helix	trans	-61	-45.1	178.3	-67	166.6	0	0	0	110.4	I322 S323 T329 A330 Y405 V514 F521	I322-I326 HydrophobicContact CG2-CD1 3.89Å; I322-I326 VanDerWaalsContact O-CG1 3.3Å; I322-I326 WeakPolarHBondContact O-CG1 3.08Å; I322-I326 PolarHBondContact O-N 2.92Å; S323-I326 WeakPolarHBondContact O-CB 3.36Å; S323-I326 PolarHBondContact O-N 3.39Å; S323-I326 VanDerWaalsContact O-N 3.12Å; I326-T329 PolarHBondContact O-N 2.85Å; I326-A330 PolarHBondContact O-N 3.37Å; I326-Y405 HydrophobicContact CG2-CE1 4.38Å; I326-V514 HydrophobicContact CG2-CG1 3.76Å; I326-V514 VanDerWaalsContact CG2-O 3.3Å; I326-V514 WeakPolarHBondContact CG2-O 3.33Å; I326-V514 WeakPolarHBondContact O-CG1 3.21Å; I326-F521 HydrophobicContact CD1-CB 4.48Å; I326-F521 HydrophobicContact CD1-CD2 4.36Å; I326-F521 HydrophobicContact CD1-CG 4.25Å
327	G	96	Very high	91.4	Very high	0 Å²	0	26.2 Å²	26.2	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-61.4	-49.2	179.1	0	0	0	0	0	114	S323 H324 L325 T329 A330 F331 Y405	S323-G327 PolarHBondContact O-N 2.95Å; H324-G327 PolarHBondContact O-N 2.93Å; L325-G327 VanDerWaalsContact C-N 3.34Å; L325-G327 PolarHBondContact O-N 3.22Å; G327-T329 VanDerWaalsContact C-N 3.32Å; G327-T329 PolarHBondContact O-N 3.38Å; G327-A330 PolarHBondContact O-N 3.12Å; G327-F331 VanDerWaalsContact O-CB 3.31Å; G327-F331 WeakPolarHBondContact O-CB 3.33Å; G327-F331 PolarHBondContact O-N 2.89Å; G327-Y405 WeakPolarHBondContact CA-OH 3.43Å; G327-Y405 PolarHBondContact N-OH 2.93Å
328	W	94.6	Very high	91.5	Very high	12 Å²	12	26.1 Å²	26.1	5%	0.045	12%	0.122	C	C	.	.	H	α-helix	trans	-66.5	-35.1	175.9	-79.4	107	0	0	0	112.3	H324 F331 L332 L438 Y439 V483 A486	H324-W328 AromaticContact CD2-CD1 3.54Å; H324-W328 AromaticContact CD2-NE1 3.68Å; H324-W328 AromaticContact CE1-CD1 3.52Å; H324-W328 AromaticContact CE1-NE1 3.01Å; H324-W328 PolarHBondContact CE1-NE1 3.43Å; H324-W328 AromaticContact CG-CD1 3.83Å; H324-W328 AromaticContact ND1-CD1 3.78Å; H324-W328 AromaticContact ND1-NE1 3.7Å; H324-W328 AromaticContact NE2-CD1 3.35Å; H324-W328 VanDerWaalsContact NE2-CD1 3.35Å; H324-W328 AromaticContact NE2-NE1 2.95Å; H324-W328 PolarHBondContact NE2-NE1 2.98Å; H324-W328 VanDerWaalsContact O-CD1 3.3Å; H324-W328 PolarHBondContact O-N 2.85Å; W328-F331 AromaticContact CE3-CD1 3.96Å; W328-F331 HydrophobicContact CE3-CD1 3.96Å; W328-F331 AromaticContact CZ3-CD1 3.72Å; W328-F331 HydrophobicContact CZ3-CD1 3.72Å; W328-F331 HydrophobicContact CZ3-CE1 4.08Å; W328-F331 PolarHBondContact O-N 3.35Å; W328-L332 HydrophobicContact CB-CD1 4.29Å; W328-L332 HydrophobicContact CE3-CD1 4.24Å; W328-L332 HydrophobicContact CE3-CD2 4.38Å; W328-L332 HydrophobicContact CE3-CG 4.06Å; W328-L332 WeakPolarHBondContact O-CB 3.29Å; W328-L332 WeakPolarHBondContact O-CD1 3.45Å; W328-L332 WeakPolarHBondContact O-CG 3.41Å; W328-L332 PolarHBondContact O-N 3.1Å; W328-L438 HydrophobicContact CD2-CD1 4.08Å; W328-L438 HydrophobicContact CE3-CD1 4.38Å; W328-L438 HydrophobicContact CG-CD1 4.36Å; W328-L438 HydrophobicContact CZ2-CB 3.94Å; W328-Y439 HydrophobicContact CH2-CD1 4.36Å; W328-Y439 HydrophobicContact CH2-CD2 4.45Å; W328-Y439 AromaticContact CH2-CE1 3.77Å; W328-Y439 HydrophobicContact CH2-CE1 3.77Å; W328-Y439 AromaticContact CH2-CE2 3.89Å; W328-Y439 HydrophobicContact CH2-CE2 3.89Å; W328-Y439 AromaticContact CH2-CZ 3.53Å; W328-Y439 HydrophobicContact CZ2-CD1 4.15Å; W328-Y439 AromaticContact CZ2-CE1 3.89Å; W328-Y439 HydrophobicContact CZ2-CE1 3.89Å; W328-V483 HydrophobicContact CD2-CG1 3.86Å; W328-V483 HydrophobicContact CD2-CG2 4.19Å; W328-V483 HydrophobicContact CE3-CG1 4.08Å; W328-V483 HydrophobicContact CG-CB 4.4Å; W328-V483 HydrophobicContact CG-CG1 4.13Å; W328-V483 HydrophobicContact CG-CG2 4.06Å; W328-A486 HydrophobicContact CB-CB 3.59Å
329	T	94.6	Very high	91.4	Very high	26 Å²	26	23.1 Å²	23.1	16%	0.16	12%	0.115	C	C	.	.	H	α-helix	trans	-61.8	-48.2	174.8	-58.2	0	0	0	0	110.5	L325 I326 G327 S333 A486 V490 V514	L325-T329 VanDerWaalsContact O-CB 3.31Å; L325-T329 WeakPolarHBondContact O-CB 3.47Å; L325-T329 PolarHBondContact O-N 3.24Å; L325-T329 PolarHBondContact O-OG1 3.43Å; I326-T329 PolarHBondContact O-N 2.85Å; G327-T329 VanDerWaalsContact C-N 3.32Å; G327-T329 PolarHBondContact O-N 3.38Å; T329-S333 WeakPolarHBondContact O-CB 3.32Å; T329-S333 PolarHBondContact O-N 3.36Å; T329-S333 PolarHBondContact O-OG 2.98Å; T329-S333 VanDerWaalsContact O-OG 3.06Å; T329-A486 WeakPolarHBondContact OG1-CB 3.34Å; T329-V490 HydrophobicContact CG2-CG2 3.89Å; T329-V490 WeakPolarHBondContact O-CG2 3.5Å; T329-V514 HydrophobicContact CG2-CG1 4.34Å
330	A	95.2	Very high	91.2	Very high	0 Å²	0	20.5 Å²	20.5	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-60.7	-49.2	175.8	0	0	0	0	0	111.8	I326 G327 S333 N334 F408 A511 V514 A515	I326-A330 PolarHBondContact O-N 3.37Å; G327-A330 PolarHBondContact O-N 3.12Å; A330-S333 PolarHBondContact O-OG 3Å; A330-N334 PolarHBondContact O-N 3.32Å; A330-F408 HydrophobicContact CB-CE1 4.05Å; A330-A511 WeakPolarHBondContact O-CB 3.49Å; A330-V514 HydrophobicContact CB-CB 4.03Å; A330-V514 HydrophobicContact CB-CG1 3.83Å; A330-A515 HydrophobicContact CB-CB 3.94Å
331	F	94.7	Very high	91.1	Very high	12 Å²	12	20.5 Å²	20.5	5%	0.053	11%	0.106	C	C	.	.	H	α-helix	trans	-64.3	-49.5	-177.1	-175.7	-106.7	0	0	0	112.4	G327 W328 N334 M335 F408 F431 M434 L438	G327-F331 VanDerWaalsContact O-CB 3.31Å; G327-F331 WeakPolarHBondContact O-CB 3.33Å; G327-F331 PolarHBondContact O-N 2.89Å; W328-F331 AromaticContact CE3-CD1 3.96Å; W328-F331 HydrophobicContact CE3-CD1 3.96Å; W328-F331 AromaticContact CZ3-CD1 3.72Å; W328-F331 HydrophobicContact CZ3-CD1 3.72Å; W328-F331 HydrophobicContact CZ3-CE1 4.08Å; W328-F331 PolarHBondContact O-N 3.35Å; F331-N334 PolarHBondContact O-N 3.48Å; F331-M335 HydrophobicContact CD1-CG 4Å; F331-M335 HydrophobicContact CD2-CE 4.44Å; F331-M335 HydrophobicContact CD2-CG 4.29Å; F331-M335 HydrophobicContact CE1-CG 3.65Å; F331-M335 HydrophobicContact CE1-SD 4.36Å; F331-M335 HydrophobicContact CE2-CE 3.69Å; F331-M335 HydrophobicContact CE2-CG 3.96Å; F331-M335 HydrophobicContact CE2-SD 4.2Å; F331-M335 HydrophobicContact CG-CG 4.31Å; F331-M335 HydrophobicContact CZ-CE 3.92Å; F331-M335 HydrophobicContact CZ-CG 3.61Å; F331-M335 HydrophobicContact CZ-SD 3.81Å; F331-M335 WeakPolarHBondContact O-CB 3.19Å; F331-M335 VanDerWaalsContact O-CG 3.24Å; F331-M335 WeakPolarHBondContact O-CG 3.43Å; F331-M335 PolarHBondContact O-N 3.33Å; F331-F408 HydrophobicContact CD2-CD2 4.49Å; F331-F408 AromaticContact CD2-CE2 3.87Å; F331-F408 HydrophobicContact CD2-CE2 3.87Å; F331-F408 HydrophobicContact CD2-CZ 4.22Å; F331-F408 HydrophobicContact CE2-CE2 4.48Å; F331-F431 HydrophobicContact CE2-CB 4.38Å; F331-F431 WeakPolarHBondContact CE2-O 3.17Å; F331-M434 HydrophobicContact CB-CG 4.34Å; F331-M434 HydrophobicContact CD2-CB 4.08Å; F331-M434 HydrophobicContact CD2-CG 3.84Å; F331-M434 HydrophobicContact CE2-CB 4.47Å; F331-M434 HydrophobicContact CG-CG 4.42Å; F331-L438 HydrophobicContact CB-CD1 3.79Å; F331-L438 HydrophobicContact CG-CD1 4.14Å
332	L	90.9	Very high	91.1	Very high	20 Å²	20	20.2 Å²	20.2	11%	0.105	10%	0.104	C	C	.	.	H	α-helix	trans	-67.6	-36.2	-179.5	-68.2	166.2	0	0	0	112.6	W328 N334 M335 L336 A486 Q487 V490	W328-L332 HydrophobicContact CB-CD1 4.29Å; W328-L332 HydrophobicContact CE3-CD1 4.24Å; W328-L332 HydrophobicContact CE3-CD2 4.38Å; W328-L332 HydrophobicContact CE3-CG 4.06Å; W328-L332 WeakPolarHBondContact O-CB 3.29Å; W328-L332 WeakPolarHBondContact O-CD1 3.45Å; W328-L332 WeakPolarHBondContact O-CG 3.41Å; W328-L332 PolarHBondContact O-N 3.1Å; L332-N334 VanDerWaalsContact C-N 3.28Å; L332-N334 PolarHBondContact O-N 3.43Å; L332-M335 PolarHBondContact O-N 2.96Å; L332-L336 WeakPolarHBondContact O-CB 3.43Å; L332-L336 WeakPolarHBondContact O-CG 3.17Å; L332-L336 PolarHBondContact O-N 2.98Å; L332-A486 HydrophobicContact CD1-CB 3.99Å; L332-Q487 HydrophobicContact CD1-CB 4.32Å; L332-Q487 HydrophobicContact CD1-CG 3.42Å; L332-Q487 VanDerWaalsContact CD1-CG 3.42Å; L332-Q487 HydrophobicContact CD2-CG 4.41Å; L332-V490 HydrophobicContact CB-CG2 4.26Å
333	S	89.4	Confident	90.8	Very high	3 Å²	3	16.7 Å²	16.7	2%	0.021	9%	0.086	C	C	.	.	H	α-helix	trans	-56.4	-45.7	175.7	65.4	0	0	0	0	111.3	T329 A330 V507 A511	T329-S333 WeakPolarHBondContact O-CB 3.32Å; T329-S333 PolarHBondContact O-N 3.36Å; T329-S333 PolarHBondContact O-OG 2.98Å; T329-S333 VanDerWaalsContact O-OG 3.06Å; A330-S333 PolarHBondContact O-OG 3Å; S333-V507 WeakPolarHBondContact O-CG1 3.27Å; S333-A511 WeakPolarHBondContact OG-CA 3.07Å; S333-A511 WeakPolarHBondContact OG-CB 3.29Å
334	N	90	Very high	90.6	Very high	0 Å²	0	19 Å²	19	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-69.8	-50.6	174.9	-176.6	79.7	0	0	0	111.7	A330 F331 L332 L336 F337 F338 F408 T412 F431 A511	A330-N334 PolarHBondContact O-N 3.32Å; F331-N334 PolarHBondContact O-N 3.48Å; L332-N334 VanDerWaalsContact C-N 3.28Å; L332-N334 PolarHBondContact O-N 3.43Å; N334-L336 PolarHBondContact O-N 2.92Å; N334-F337 PolarHBondContact O-N 3.42Å; N334-F338 WeakPolarHBondContact O-CA 3.22Å; N334-F338 WeakPolarHBondContact O-CB 3.39Å; N334-F338 PolarHBondContact O-N 2.63Å; N334-F408 HydrophobicContact CB-CZ 3.89Å; N334-T412 HydrophobicContact CB-CG2 4.41Å; N334-F431 WeakPolarHBondContact ND2-CE2 3.4Å; N334-F431 WeakPolarHBondContact ND2-CZ 3.48Å; N334-A511 HydrophobicContact CB-CB 3.81Å
335	M	87	Confident	90.6	Very high	27 Å²	27	20.6 Å²	20.6	13%	0.133	11%	0.106	C	C	.	.	H	α-helix	trans	-58.6	-44	-173.4	-73.6	-71.9	130.2	0	0	113.7	F331 L332 F337 L374 F431	F331-M335 HydrophobicContact CD1-CG 4Å; F331-M335 HydrophobicContact CD2-CE 4.44Å; F331-M335 HydrophobicContact CD2-CG 4.29Å; F331-M335 HydrophobicContact CE1-CG 3.65Å; F331-M335 HydrophobicContact CE1-SD 4.36Å; F331-M335 HydrophobicContact CE2-CE 3.69Å; F331-M335 HydrophobicContact CE2-CG 3.96Å; F331-M335 HydrophobicContact CE2-SD 4.2Å; F331-M335 HydrophobicContact CG-CG 4.31Å; F331-M335 HydrophobicContact CZ-CE 3.92Å; F331-M335 HydrophobicContact CZ-CG 3.61Å; F331-M335 HydrophobicContact CZ-SD 3.81Å; F331-M335 WeakPolarHBondContact O-CB 3.19Å; F331-M335 VanDerWaalsContact O-CG 3.24Å; F331-M335 WeakPolarHBondContact O-CG 3.43Å; F331-M335 PolarHBondContact O-N 3.33Å; L332-M335 PolarHBondContact O-N 2.96Å; M335-F337 VanDerWaalsContact C-N 3.31Å; M335-F337 PolarHBondContact O-N 3.39Å; M335-L374 HydrophobicContact CE-CD2 4.16Å; M335-L374 HydrophobicContact SD-CD2 3.56Å; M335-L374 VanDerWaalsContact SD-CD2 3.56Å; M335-F431 HydrophobicContact CE-CB 3.51Å; M335-F431 HydrophobicContact CE-CD2 3.3Å; M335-F431 HydrophobicContact CE-CE2 4.18Å; M335-F431 HydrophobicContact CE-CG 3.65Å
336	L	81.2	Confident	90.5	Very high	73 Å²	73	20 Å²	20	38%	0.382	10%	0.103	S	C	.	.	H	α-helix	trans	-68.3	-28.5	-175	-71.6	174.5	0	0	0	113.6	W74 L332 N334 V490	W74-L336 HydrophobicContact CE3-CD2 4.25Å; W74-L336 HydrophobicContact CZ3-CD2 3.74Å; L332-L336 WeakPolarHBondContact O-CB 3.43Å; L332-L336 WeakPolarHBondContact O-CG 3.17Å; L332-L336 PolarHBondContact O-N 2.98Å; N334-L336 PolarHBondContact O-N 2.92Å; L336-V490 HydrophobicContact CD1-CG1 3.84Å
337	F	84.1	Confident	90.3	Very high	49 Å²	49	21.6 Å²	21.6	22%	0.215	11%	0.107	C	C	.	.	H	α-helix	trans	-112.7	5.5	-177.7	-65.3	-94.5	0	0	0	112.6	N334 M335 T339 D340 F341 L494 V507	N334-F337 PolarHBondContact O-N 3.42Å; M335-F337 VanDerWaalsContact C-N 3.31Å; M335-F337 PolarHBondContact O-N 3.39Å; F337-T339 PolarHBondContact O-N 2.91Å; F337-D340 PolarHBondContact O-N 3.27Å; F337-F341 WeakPolarHBondContact O-CB 3.31Å; F337-F341 PolarHBondContact O-N 2.99Å; F337-L494 HydrophobicContact CD2-CD2 3.34Å; F337-L494 HydrophobicContact CD2-CG 4.41Å; F337-L494 HydrophobicContact CE2-CB 4.11Å; F337-L494 HydrophobicContact CE2-CD2 3.29Å; F337-L494 HydrophobicContact CE2-CG 4.04Å; F337-L494 HydrophobicContact CG-CD2 4.28Å; F337-L494 HydrophobicContact CZ-CB 4.45Å; F337-L494 HydrophobicContact CZ-CD2 4.19Å; F337-V507 HydrophobicContact CB-CB 4.37Å; F337-V507 HydrophobicContact CB-CG1 3.86Å; F337-V507 HydrophobicContact CB-CG2 4.23Å; F337-V507 HydrophobicContact CD1-CG2 4.46Å; F337-V507 HydrophobicContact CD2-CG1 4.14Å; F337-V507 HydrophobicContact CD2-CG2 4.46Å; F337-V507 HydrophobicContact CG-CG1 4.2Å; F337-V507 HydrophobicContact CG-CG2 4.13Å
338	F	88	Confident	90.1	Very high	0 Å²	0	31.7 Å²	31.7	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-64.5	-43.9	-172.7	178.1	-107.7	0	0	0	112.6	N334 D340 F341 M342 G370 L374 T424 C428 F431	N334-F338 WeakPolarHBondContact O-CA 3.22Å; N334-F338 WeakPolarHBondContact O-CB 3.39Å; N334-F338 PolarHBondContact O-N 2.63Å; F338-D340 VanDerWaalsContact C-N 3.32Å; F338-F341 WeakPolarHBondContact O-CB 3.29Å; F338-F341 PolarHBondContact O-N 2.84Å; F338-M342 HydrophobicContact CE1-CE 4.28Å; F338-M342 HydrophobicContact CZ-CE 3.83Å; F338-M342 PolarHBondContact O-N 3.4Å; F338-G370 WeakPolarHBondContact CE1-O 3.26Å; F338-L374 HydrophobicContact CB-CD2 4.47Å; F338-L374 HydrophobicContact CD1-CD2 3.73Å; F338-L374 HydrophobicContact CD1-CG 3.97Å; F338-L374 HydrophobicContact CE1-CD2 4.43Å; F338-L374 HydrophobicContact CG-CD2 4.37Å; F338-T424 HydrophobicContact CE2-CG2 3.71Å; F338-T424 HydrophobicContact CZ-CG2 3.75Å; F338-C428 WeakPolarHBondContact CZ-SG 3.46Å; F338-F431 AromaticContact CD2-CE2 3.81Å; F338-F431 HydrophobicContact CD2-CE2 3.81Å; F338-F431 HydrophobicContact CD2-CZ 4.39Å; F338-F431 AromaticContact CE2-CE2 3.7Å; F338-F431 HydrophobicContact CE2-CE2 3.7Å; F338-F431 HydrophobicContact CE2-CZ 4.23Å; F338-F431 HydrophobicContact CG-CE2 4.44Å; F338-F431 HydrophobicContact CZ-CE2 4.24Å
339	T	86.9	Confident	89.8	Confident	33 Å²	33	31.5 Å²	31.5	20%	0.202	15%	0.147	C	C	.	.	H	α-helix	trans	-64.6	-39.8	178.1	47.5	0	0	0	0	111.3	F337 M342 G343 L374	F337-T339 PolarHBondContact O-N 2.91Å; T339-M342 WeakPolarHBondContact O-CB 3.34Å; T339-M342 PolarHBondContact O-N 2.74Å; T339-G343 PolarHBondContact O-N 2.9Å; T339-L374 HydrophobicContact CG2-CD1 3.95Å
340	D	86.6	Confident	89.5	Confident	31 Å²	31	33.5 Å²	33.5	17%	0.166	16%	0.157	C	C	.	.	H	α-helix	trans	-67.2	-40.7	176.1	-167.8	46.4	0	0	0	112.1	F337 F338 M342 G343 Q344 Y363 V504	F337-D340 PolarHBondContact O-N 3.27Å; F338-D340 VanDerWaalsContact C-N 3.32Å; D340-M342 VanDerWaalsContact C-N 3.33Å; D340-M342 PolarHBondContact O-N 3.26Å; D340-G343 PolarHBondContact O-N 3.49Å; D340-Q344 WeakPolarHBondContact O-CB 3.1Å; D340-Q344 PolarHBondContact O-N 3.32Å; D340-Q344 PolarHBondContact OD1-NE2 2.97Å; D340-Q344 PolarHBondContact OD2-NE2 3.31Å; D340-Y363 VanDerWaalsContact OD1-CE2 3.3Å; D340-Y363 WeakPolarHBondContact OD1-CE2 3.5Å; D340-Y363 PolarHBondContact OD1-OH 3.28Å; D340-V504 WeakPolarHBondContact OD2-CG1 3.25Å
341	F	90.6	Very high	88.9	Confident	2 Å²	2	34.9 Å²	34.9	1%	0.009	17%	0.166	C	C	.	.	H	α-helix	trans	-59.8	-42	170.4	172.3	-90.5	0	0	0	111.8	F337 F338 I345 V346 I415 P419 V504 V505 V508	F337-F341 WeakPolarHBondContact O-CB 3.31Å; F337-F341 PolarHBondContact O-N 2.99Å; F338-F341 WeakPolarHBondContact O-CB 3.29Å; F338-F341 PolarHBondContact O-N 2.84Å; F341-I345 HydrophobicContact CD2-CB 3.93Å; F341-I345 HydrophobicContact CD2-CG1 3.74Å; F341-I345 HydrophobicContact CD2-CG2 4.37Å; F341-I345 HydrophobicContact CE2-CB 3.81Å; F341-I345 HydrophobicContact CE2-CG1 3.94Å; F341-I345 HydrophobicContact CE2-CG2 3.75Å; F341-I345 HydrophobicContact CG-CB 4.46Å; F341-I345 HydrophobicContact CG-CG1 4.5Å; F341-I345 HydrophobicContact CZ-CB 4.25Å; F341-I345 HydrophobicContact CZ-CG2 4.02Å; F341-I345 WeakPolarHBondContact O-CA 3.41Å; F341-I345 WeakPolarHBondContact O-CB 3.18Å; F341-I345 PolarHBondContact O-N 3.42Å; F341-V346 HydrophobicContact CD1-CG2 4.04Å; F341-V346 HydrophobicContact CE1-CG2 3.53Å; F341-V346 HydrophobicContact CZ-CG2 4.22Å; F341-V346 PolarHBondContact O-N 3.5Å; F341-I415 HydrophobicContact CD1-CG2 4.38Å; F341-I415 HydrophobicContact CE1-CG2 3.39Å; F341-I415 HydrophobicContact CZ-CG2 3.71Å; F341-P419 HydrophobicContact CZ-CB 4.32Å; F341-V504 HydrophobicContact CB-CG2 4.45Å; F341-V504 HydrophobicContact CD2-CG2 4.42Å; F341-V505 HydrophobicContact CE2-CG2 4.23Å; F341-V508 HydrophobicContact CB-CG2 4.46Å; F341-V508 HydrophobicContact CD1-CG2 4.21Å; F341-V508 HydrophobicContact CD2-CG2 3.56Å; F341-V508 HydrophobicContact CE1-CG2 4.38Å; F341-V508 HydrophobicContact CE2-CB 4.38Å; F341-V508 HydrophobicContact CE2-CG2 3.74Å; F341-V508 HydrophobicContact CG-CG2 3.81Å; F341-V508 HydrophobicContact CZ-CG2 4.16Å
342	M	91	Very high	88.4	Confident	0 Å²	0	43.8 Å²	43.8	0%	0	20%	0.2	C	C	.	.	I	π-helix	trans	-63.4	-43.7	176.4	-170.1	72.2	86.7	0	0	111.1	F338 T339 D340 V346 Y347 G366 V369 T424 L425	F338-M342 HydrophobicContact CE1-CE 4.28Å; F338-M342 HydrophobicContact CZ-CE 3.83Å; F338-M342 PolarHBondContact O-N 3.4Å; T339-M342 WeakPolarHBondContact O-CB 3.34Å; T339-M342 PolarHBondContact O-N 2.74Å; D340-M342 VanDerWaalsContact C-N 3.33Å; D340-M342 PolarHBondContact O-N 3.26Å; M342-V346 HydrophobicContact CG-CB 4.46Å; M342-V346 WeakPolarHBondContact O-CB 3.39Å; M342-V346 PolarHBondContact O-N 3.15Å; M342-V346 HydrophobicContact SD-CB 3.63Å; M342-V346 HydrophobicContact SD-CG1 3.56Å; M342-V346 VanDerWaalsContact SD-CG1 3.56Å; M342-V346 HydrophobicContact SD-CG2 3.85Å; M342-Y347 HydrophobicContact CG-CD2 4.08Å; M342-Y347 HydrophobicContact CG-CE2 4.25Å; M342-Y347 WeakPolarHBondContact O-CD2 3.4Å; M342-Y347 PolarHBondContact O-N 3.39Å; M342-Y347 HydrophobicContact SD-CD2 4.29Å; M342-Y347 HydrophobicContact SD-CE2 4.21Å; M342-G366 WeakPolarHBondContact CB-O 3.19Å; M342-G366 WeakPolarHBondContact CG-O 3.08Å; M342-V369 HydrophobicContact CE-CG1 4.25Å; M342-V369 HydrophobicContact SD-CG1 4.47Å; M342-T424 HydrophobicContact CE-CG2 3.67Å; M342-T424 HydrophobicContact SD-CG2 4.33Å; M342-L425 HydrophobicContact CE-CD2 4.11Å; M342-L425 HydrophobicContact CE-CG 4.48Å
343	G	87.5	Confident	88	Confident	0 Å²	0	43.9 Å²	43.9	0%	0	20%	0.203	C	C	.	.	I	π-helix	trans	-60.8	-57.2	175	0	0	0	0	0	113.4	T339 D340 R348 G349	T339-G343 PolarHBondContact O-N 2.9Å; D340-G343 PolarHBondContact O-N 3.49Å; G343-R348 PolarHBondContact O-N 2.98Å; G343-G349 PolarHBondContact O-N 3.02Å
344	Q	89.7	Confident	87.7	Confident	48 Å²	48	47.2 Å²	47.2	22%	0.224	23%	0.231	C	C	.	.	I	π-helix	trans	-80.4	-39.3	-170.5	-69.9	-176.7	47.5	0	0	114.2	D340 R348 P351 Y363 V504	D340-Q344 WeakPolarHBondContact O-CB 3.1Å; D340-Q344 PolarHBondContact O-N 3.32Å; D340-Q344 PolarHBondContact OD1-NE2 2.97Å; D340-Q344 PolarHBondContact OD2-NE2 3.31Å; Q344-R348 VanDerWaalsContact O-CA 3.27Å; Q344-R348 WeakPolarHBondContact O-CA 3.21Å; Q344-P351 HydrophobicContact CG-CG 4.04Å; Q344-Y363 HydrophobicContact CG-CD2 4.09Å; Q344-Y363 HydrophobicContact CG-CE2 3.97Å; Q344-V504 HydrophobicContact CB-CG2 4.08Å
345	I	93.1	Very high	87	Confident	36 Å²	36	53.5 Å²	53.5	19%	0.185	26%	0.26	C	S	.	.	I	π-helix	trans	-100.9	-47.3	-170.3	-55.6	-56.1	0	0	0	111.5	F341 P419 V504 V505	F341-I345 HydrophobicContact CD2-CB 3.93Å; F341-I345 HydrophobicContact CD2-CG1 3.74Å; F341-I345 HydrophobicContact CD2-CG2 4.37Å; F341-I345 HydrophobicContact CE2-CB 3.81Å; F341-I345 HydrophobicContact CE2-CG1 3.94Å; F341-I345 HydrophobicContact CE2-CG2 3.75Å; F341-I345 HydrophobicContact CG-CB 4.46Å; F341-I345 HydrophobicContact CG-CG1 4.5Å; F341-I345 HydrophobicContact CZ-CB 4.25Å; F341-I345 HydrophobicContact CZ-CG2 4.02Å; F341-I345 WeakPolarHBondContact O-CA 3.41Å; F341-I345 WeakPolarHBondContact O-CB 3.18Å; F341-I345 PolarHBondContact O-N 3.42Å; I345-P419 HydrophobicContact CG2-CB 3.76Å; I345-P419 HydrophobicContact CG2-CG 4.03Å; I345-V504 HydrophobicContact CD1-CG2 3.82Å; I345-V504 HydrophobicContact CG1-CG2 3.43Å; I345-V504 VanDerWaalsContact CG1-CG2 3.43Å; I345-V505 HydrophobicContact CB-CG2 4.34Å; I345-V505 HydrophobicContact CD1-CG2 3.56Å; I345-V505 HydrophobicContact CG1-CG2 3.63Å; I345-V505 HydrophobicContact CG2-CG2 3.79Å
346	V	93.4	Very high	86.8	Confident	18 Å²	18	59.9 Å²	59.9	11%	0.109	29%	0.294	C	S	.	.	I	π-helix	trans	-77.4	-46.1	-175.7	-180	0	0	0	0	110.8	F341 M342 P419 V421	F341-V346 HydrophobicContact CD1-CG2 4.04Å; F341-V346 HydrophobicContact CE1-CG2 3.53Å; F341-V346 HydrophobicContact CZ-CG2 4.22Å; F341-V346 PolarHBondContact O-N 3.5Å; M342-V346 HydrophobicContact CG-CB 4.46Å; M342-V346 WeakPolarHBondContact O-CB 3.39Å; M342-V346 PolarHBondContact O-N 3.15Å; M342-V346 HydrophobicContact SD-CB 3.63Å; M342-V346 HydrophobicContact SD-CG1 3.56Å; M342-V346 VanDerWaalsContact SD-CG1 3.56Å; M342-V346 HydrophobicContact SD-CG2 3.85Å; V346-P419 HydrophobicContact CG2-CB 4.17Å; V346-V421 HydrophobicContact CG1-CB 4.24Å; V346-V421 HydrophobicContact CG1-CG2 3.7Å
347	Y	92.4	Very high	87.2	Confident	63 Å²	63	57.5 Å²	57.5	25%	0.247	28%	0.284	C	S	.	.	S	Bend	trans	-89.3	-16.7	178	-85.8	-100.3	0	0	0	113.9	M342 G349 I362 R365 G366 V369 V421	M342-Y347 HydrophobicContact CG-CD2 4.08Å; M342-Y347 HydrophobicContact CG-CE2 4.25Å; M342-Y347 WeakPolarHBondContact O-CD2 3.4Å; M342-Y347 PolarHBondContact O-N 3.39Å; M342-Y347 HydrophobicContact SD-CD2 4.29Å; M342-Y347 HydrophobicContact SD-CE2 4.21Å; Y347-G349 VanDerWaalsContact C-N 3.26Å; Y347-G349 PolarHBondContact O-N 3.48Å; Y347-I362 WeakPolarHBondContact O-CG2 3.14Å; Y347-R365 HydrophobicContact CD1-CG 4.39Å; Y347-R365 HydrophobicContact CE1-CG 3.96Å; Y347-G366 VanDerWaalsContact CD2-CA 3.41Å; Y347-V369 HydrophobicContact CE2-CB 3.96Å; Y347-V369 HydrophobicContact CE2-CG1 3.96Å; Y347-V369 HydrophobicContact CE2-CG2 4.27Å; Y347-V369 WeakPolarHBondContact OH-CG2 3.25Å; Y347-V421 HydrophobicContact CD2-CG2 4.4Å; Y347-V421 HydrophobicContact CE2-CG1 4.01Å; Y347-V421 HydrophobicContact CE2-CG2 3.76Å
348	R	92.1	Very high	87.5	Confident	213 Å²	213	59.9 Å²	59.9	80%	0.804	30%	0.302	S	S	*	.			trans	61	33.2	-177.6	-52.1	-179.1	179.8	-176	-0.9	113.4	G343 Q344	G343-R348 PolarHBondContact O-N 2.98Å; Q344-R348 VanDerWaalsContact O-CA 3.27Å; Q344-R348 WeakPolarHBondContact O-CA 3.21Å
349	G	88	Confident	87.6	Confident	8 Å²	8	64.5 Å²	64.5	8%	0.082	32%	0.324	C	S	.	.			trans	-82	163.5	171.2	0	0	0	0	0	112.1	G343 Y347 E359	G343-G349 PolarHBondContact O-N 3.02Å; Y347-G349 VanDerWaalsContact C-N 3.26Å; Y347-G349 PolarHBondContact O-N 3.48Å; G349-E359 WeakPolarHBondContact CA-O 3.45Å
350	D	87.5	Confident	87.5	Confident	68 Å²	68	64.5 Å²	64.5	36%	0.364	32%	0.321	S	S	.	.			trans	-119.4	112	177	-178.5	4	0	0	0	110.5	Y352 S353 E359	D350-Y352 PolarHBondContact O-N 3.23Å; D350-Y352 PolarHBondContact OD1-N 2.89Å; D350-S353 PolarHBondContact O-N 3.33Å; D350-S353 PolarHBondContact O-OG 3.09Å; D350-E359 HydrophobicContact CB-CB 4.06Å; D350-E359 PolarHBondContact N-O 2.92Å; D350-E359 VanDerWaalsContact N-O 3.15Å
351	P	82	Confident	87.5	Confident	28 Å²	28	67.5 Å²	67.5	18%	0.182	34%	0.337	C	S	.	.	T	Hydrogen-bonded Turn	trans	-66.7	-17.6	178.5	26.8	-34.4	0	0	0	113.8	Q344 Y363	Q344-P351 HydrophobicContact CG-CG 4.04Å; P351-Y363 HydrophobicContact CB-CD1 4.05Å; P351-Y363 HydrophobicContact CB-CD2 3.99Å; P351-Y363 HydrophobicContact CB-CE1 3.83Å; P351-Y363 HydrophobicContact CB-CE2 3.77Å; P351-Y363 HydrophobicContact CB-CG 4.12Å; P351-Y363 HydrophobicContact CG-CD2 4.26Å; P351-Y363 HydrophobicContact CG-CE2 4.06Å
352	Y	85.2	Confident	87.5	Confident	199 Å²	199	70.5 Å²	70.5	78%	0.78	35%	0.352	S	S	*	.	T	Hydrogen-bonded Turn	trans	-95.9	-4.2	-178.6	-55.6	-72.1	0	0	0	113.3	D350	D350-Y352 PolarHBondContact O-N 3.23Å; D350-Y352 PolarHBondContact OD1-N 2.89Å
353	S	82.2	Confident	87.3	Confident	22 Å²	22	72.5 Å²	72.5	15%	0.154	36%	0.36	C	S	.	.	S	Bend	trans	-69.9	160.8	174.9	65.7	0	0	0	0	111.4	D350 H355 S357 F360	D350-S353 PolarHBondContact O-N 3.33Å; D350-S353 PolarHBondContact O-OG 3.09Å; S353-H355 PolarHBondContact O-N 3.28Å; S353-S357 WeakPolarHBondContact CB-OG 3.22Å; S353-S357 PolarHBondContact OG-OG 3.05Å; S353-F360 WeakPolarHBondContact OG-CA 3.24Å; S353-F360 WeakPolarHBondContact OG-CB 3.17Å; S353-F360 PolarHBondContact OG-N 3.18Å
354	A	83.1	Confident	87.1	Confident	73 Å²	73	76.9 Å²	76.9	60%	0.603	38%	0.381	S	S	*	.			trans	-60.8	138.6	-179.3	0	0	0	0	0	110.1	N356 S357 F360	A354-N356 PolarHBondContact O-N 3.43Å; A354-S357 WeakPolarHBondContact O-CA 3.49Å; A354-S357 WeakPolarHBondContact O-CB 3.24Å; A354-S357 PolarHBondContact O-N 2.99Å; A354-S357 PolarHBondContact O-OG 2.96Å; A354-F360 WeakPolarHBondContact O-CB 3.26Å
355	H	76.1	Confident	86.9	Confident	132 Å²	132	81 Å²	81	61%	0.611	39%	0.394	S	S	*	.	T	Hydrogen-bonded Turn	trans	-54.3	-24.9	-175.5	-70	-61.7	0	0	0	115.5	S353 F360	S353-H355 PolarHBondContact O-N 3.28Å; H355-F360 HydrophobicContact CB-CD1 4.31Å; H355-F360 HydrophobicContact CB-CE1 4.39Å; H355-F360 AromaticContact CE1-CE2 3.67Å; H355-F360 AromaticContact CE1-CZ 3.6Å; H355-F360 AromaticContact ND1-CD1 3.86Å; H355-F360 AromaticContact ND1-CD2 3.81Å; H355-F360 AromaticContact ND1-CE1 3.34Å; H355-F360 VanDerWaalsContact ND1-CE1 3.34Å; H355-F360 WeakPolarHBondContact ND1-CE1 3.44Å; H355-F360 AromaticContact ND1-CE2 3.29Å; H355-F360 VanDerWaalsContact ND1-CE2 3.29Å; H355-F360 WeakPolarHBondContact ND1-CE2 3.43Å; H355-F360 AromaticContact ND1-CZ 3.04Å; H355-F360 WeakPolarHBondContact ND1-CZ 3.39Å; H355-F360 WeakPolarHBondContact O-CD1 3.48Å
356	N	82.8	Confident	86.7	Confident	161 Å²	161	79.3 Å²	79.3	86%	0.861	39%	0.386	S	S	*	.	T	Hydrogen-bonded Turn	trans	-93.2	5.4	177.1	-66.4	-8.1	0	0	0	113.5	A354	A354-N356 PolarHBondContact O-N 3.43Å
357	S	87.9	Confident	86.2	Confident	24 Å²	24	80.3 Å²	80.3	17%	0.168	39%	0.392	C	S	.	.	S	Bend	trans	-86.1	154.7	-179.4	97.2	0	0	0	0	111	S353 A354 E359 F360 L361	S353-S357 WeakPolarHBondContact CB-OG 3.22Å; S353-S357 PolarHBondContact OG-OG 3.05Å; A354-S357 WeakPolarHBondContact O-CA 3.49Å; A354-S357 WeakPolarHBondContact O-CB 3.24Å; A354-S357 PolarHBondContact O-N 2.99Å; A354-S357 PolarHBondContact O-OG 2.96Å; S357-E359 WeakPolarHBondContact CB-OE2 3.42Å; S357-E359 PolarHBondContact O-N 3.29Å; S357-E359 PolarHBondContact OG-N 2.66Å; S357-E359 PolarHBondContact OG-OE2 3.08Å; S357-F360 PolarHBondContact O-N 2.92Å; S357-F360 PolarHBondContact OG-N 3.41Å; S357-L361 PolarHBondContact O-N 3.31Å
358	T	91.9	Very high	85.8	Confident	98 Å²	98	81.3 Å²	81.3	60%	0.601	40%	0.399	S	S	*	.	H	α-helix	trans	-61.7	-35.9	178.3	-50.4	0	0	0	0	111	L361 I362	T358-L361 PolarHBondContact O-N 3.38Å; T358-I362 HydrophobicContact CG2-CD1 3.95Å; T358-I362 HydrophobicContact CG2-CG1 4.46Å; T358-I362 WeakPolarHBondContact O-CB 3.43Å; T358-I362 WeakPolarHBondContact O-CG1 3.24Å; T358-I362 PolarHBondContact O-N 2.79Å
359	E	89.7	Confident	85.6	Confident	97 Å²	97	71.8 Å²	71.8	45%	0.453	36%	0.364	S	S	.	.	H	α-helix	trans	-65.3	-38.4	-179.9	-58.3	80.3	-176.6	0	0	112.2	G349 D350 S357 Y363	G349-E359 WeakPolarHBondContact CA-O 3.45Å; D350-E359 HydrophobicContact CB-CB 4.06Å; D350-E359 PolarHBondContact N-O 2.92Å; D350-E359 VanDerWaalsContact N-O 3.15Å; S357-E359 WeakPolarHBondContact CB-OE2 3.42Å; S357-E359 PolarHBondContact O-N 3.29Å; S357-E359 PolarHBondContact OG-N 2.66Å; S357-E359 PolarHBondContact OG-OE2 3.08Å; E359-Y363 PolarHBondContact O-N 3.2Å
360	F	85.3	Confident	85.5	Confident	33 Å²	33	71.4 Å²	71.4	15%	0.145	36%	0.36	C	S	.	.	H	α-helix	trans	-69.1	-43.6	176.3	-174	-95.8	0	0	0	111	S353 A354 H355 S357 I362 Y363 E364	S353-F360 WeakPolarHBondContact OG-CA 3.24Å; S353-F360 WeakPolarHBondContact OG-CB 3.17Å; S353-F360 PolarHBondContact OG-N 3.18Å; A354-F360 WeakPolarHBondContact O-CB 3.26Å; H355-F360 HydrophobicContact CB-CD1 4.31Å; H355-F360 HydrophobicContact CB-CE1 4.39Å; H355-F360 AromaticContact CE1-CE2 3.67Å; H355-F360 AromaticContact CE1-CZ 3.6Å; H355-F360 AromaticContact ND1-CD1 3.86Å; H355-F360 AromaticContact ND1-CD2 3.81Å; H355-F360 AromaticContact ND1-CE1 3.34Å; H355-F360 VanDerWaalsContact ND1-CE1 3.34Å; H355-F360 WeakPolarHBondContact ND1-CE1 3.44Å; H355-F360 AromaticContact ND1-CE2 3.29Å; H355-F360 VanDerWaalsContact ND1-CE2 3.29Å; H355-F360 WeakPolarHBondContact ND1-CE2 3.43Å; H355-F360 AromaticContact ND1-CZ 3.04Å; H355-F360 WeakPolarHBondContact ND1-CZ 3.39Å; H355-F360 WeakPolarHBondContact O-CD1 3.48Å; S357-F360 PolarHBondContact O-N 2.92Å; S357-F360 PolarHBondContact OG-N 3.41Å; F360-I362 VanDerWaalsContact C-N 3.31Å; F360-I362 PolarHBondContact O-N 3.04Å; F360-Y363 WeakPolarHBondContact O-CA 3.22Å; F360-Y363 WeakPolarHBondContact O-CB 3.36Å; F360-Y363 PolarHBondContact O-N 2.64Å; F360-Y363 VanDerWaalsContact O-N 3.11Å; F360-E364 PolarHBondContact O-N 2.99Å
361	L	86.5	Confident	85.4	Confident	95 Å²	95	70.2 Å²	70.2	50%	0.497	36%	0.357	S	S	.	.	H	α-helix	trans	-63.8	-36.1	176.9	-68.8	171.3	0	0	0	112.1	S357 T358 Y363 R365	S357-L361 PolarHBondContact O-N 3.31Å; T358-L361 PolarHBondContact O-N 3.38Å; L361-Y363 VanDerWaalsContact C-N 3.35Å; L361-R365 WeakPolarHBondContact O-CB 3.35Å; L361-R365 PolarHBondContact O-N 2.88Å
362	I	89.9	Confident	85.6	Confident	64 Å²	64	75.6 Å²	75.6	33%	0.328	37%	0.373	S	S	.	.	H	α-helix	trans	-64.9	-41	172.7	-71.5	167.6	0	0	0	110.7	Y347 T358 F360 R365 G366	Y347-I362 WeakPolarHBondContact O-CG2 3.14Å; T358-I362 HydrophobicContact CG2-CD1 3.95Å; T358-I362 HydrophobicContact CG2-CG1 4.46Å; T358-I362 WeakPolarHBondContact O-CB 3.43Å; T358-I362 WeakPolarHBondContact O-CG1 3.24Å; T358-I362 PolarHBondContact O-N 2.79Å; F360-I362 VanDerWaalsContact C-N 3.31Å; F360-I362 PolarHBondContact O-N 3.04Å; I362-R365 PolarHBondContact O-N 3.37Å; I362-G366 PolarHBondContact O-N 2.98Å
363	Y	87.7	Confident	85.9	Confident	43 Å²	43	66.1 Å²	66.1	17%	0.169	34%	0.336	C	S	.	.	H	α-helix	trans	-61.9	-51	175.6	170.7	-97.7	0	0	0	111.4	D340 Q344 P351 E359 F360 L361 R365 G366 V367	D340-Y363 VanDerWaalsContact OD1-CE2 3.3Å; D340-Y363 WeakPolarHBondContact OD1-CE2 3.5Å; D340-Y363 PolarHBondContact OD1-OH 3.28Å; Q344-Y363 HydrophobicContact CG-CD2 4.09Å; Q344-Y363 HydrophobicContact CG-CE2 3.97Å; P351-Y363 HydrophobicContact CB-CD1 4.05Å; P351-Y363 HydrophobicContact CB-CD2 3.99Å; P351-Y363 HydrophobicContact CB-CE1 3.83Å; P351-Y363 HydrophobicContact CB-CE2 3.77Å; P351-Y363 HydrophobicContact CB-CG 4.12Å; P351-Y363 HydrophobicContact CG-CD2 4.26Å; P351-Y363 HydrophobicContact CG-CE2 4.06Å; E359-Y363 PolarHBondContact O-N 3.2Å; F360-Y363 WeakPolarHBondContact O-CA 3.22Å; F360-Y363 WeakPolarHBondContact O-CB 3.36Å; F360-Y363 PolarHBondContact O-N 2.64Å; F360-Y363 VanDerWaalsContact O-N 3.11Å; L361-Y363 VanDerWaalsContact C-N 3.35Å; Y363-R365 VanDerWaalsContact C-N 3.28Å; Y363-R365 PolarHBondContact O-N 3.26Å; Y363-G366 CarbonylContact O-C 3.6Å; Y363-G366 WeakPolarHBondContact O-CA 3.5Å; Y363-G366 PolarHBondContact O-N 2.82Å; Y363-V367 HydrophobicContact CD1-CG2 4.19Å; Y363-V367 HydrophobicContact CD2-CG2 4.5Å; Y363-V367 HydrophobicContact CE1-CG2 3.66Å; Y363-V367 HydrophobicContact CE2-CG2 4Å; Y363-V367 WeakPolarHBondContact O-CG2 3.42Å; Y363-V367 PolarHBondContact O-N 3.04Å
364	E	81.9	Confident	86.2	Confident	92 Å²	92	65.8 Å²	65.8	43%	0.43	33%	0.333	S	S	.	.	H	α-helix	trans	-56	-45.1	177.6	-175.9	174.6	-145.8	0	0	110.8	F360 G366 V367 E368	F360-E364 PolarHBondContact O-N 2.99Å; E364-G366 VanDerWaalsContact C-N 3.3Å; E364-G366 PolarHBondContact O-N 3.41Å; E364-V367 WeakPolarHBondContact O-CB 3.39Å; E364-V367 PolarHBondContact O-N 3.38Å; E364-V367 VanDerWaalsContact O-N 3.09Å; E364-E368 WeakPolarHBondContact O-CG 3.47Å; E364-E368 PolarHBondContact O-N 3.24Å
365	R	87.1	Confident	86.5	Confident	135 Å²	135	63.2 Å²	63.2	51%	0.509	31%	0.31	S	S	.	.	H	α-helix	trans	-60.8	-38.5	174.8	-174.6	55.6	178.3	-178.7	0.9	112.8	Y347 L361 I362 Y363 E368 V369	Y347-R365 HydrophobicContact CD1-CG 4.39Å; Y347-R365 HydrophobicContact CE1-CG 3.96Å; L361-R365 WeakPolarHBondContact O-CB 3.35Å; L361-R365 PolarHBondContact O-N 2.88Å; I362-R365 PolarHBondContact O-N 3.37Å; Y363-R365 VanDerWaalsContact C-N 3.28Å; Y363-R365 PolarHBondContact O-N 3.26Å; R365-E368 VanDerWaalsContact CD-OE2 3.24Å; R365-E368 WeakPolarHBondContact CD-OE2 3.36Å; R365-E368 IonicContact CZ-OE2 2.7Å; R365-E368 IonicContact NE-OE2 3.03Å; R365-E368 IonicContact NH1-OE2 3.88Å; R365-E368 PolarHBondContact NH1-OE2 3.37Å; R365-V369 VanDerWaalsContact O-CG2 3.27Å; R365-V369 WeakPolarHBondContact O-CG2 3.47Å; R365-V369 PolarHBondContact O-N 3.43Å; R365-V369 VanDerWaalsContact O-N 3.09Å
366	G	87.9	Confident	87.2	Confident	0 Å²	0	59.5 Å²	59.5	0%	0	29%	0.294	C	S	.	.	H	α-helix	trans	-66.2	-38.8	174	0	0	0	0	0	112.6	M342 Y347 I362 Y363 E364 V369 G370	M342-G366 WeakPolarHBondContact CB-O 3.19Å; M342-G366 WeakPolarHBondContact CG-O 3.08Å; Y347-G366 VanDerWaalsContact CD2-CA 3.41Å; I362-G366 PolarHBondContact O-N 2.98Å; Y363-G366 CarbonylContact O-C 3.6Å; Y363-G366 WeakPolarHBondContact O-CA 3.5Å; Y363-G366 PolarHBondContact O-N 2.82Å; E364-G366 VanDerWaalsContact C-N 3.3Å; E364-G366 PolarHBondContact O-N 3.41Å; G366-V369 PolarHBondContact O-N 3.03Å; G366-G370 PolarHBondContact O-N 2.86Å
367	V	83.2	Confident	87.7	Confident	39 Å²	39	52.2 Å²	52.2	24%	0.236	26%	0.255	C	S	.	.	H	α-helix	trans	-62.7	-45.5	174.3	171.6	0	0	0	0	111.3	Y363 E364 V369 G370 C371	Y363-V367 HydrophobicContact CD1-CG2 4.19Å; Y363-V367 HydrophobicContact CD2-CG2 4.5Å; Y363-V367 HydrophobicContact CE1-CG2 3.66Å; Y363-V367 HydrophobicContact CE2-CG2 4Å; Y363-V367 WeakPolarHBondContact O-CG2 3.42Å; Y363-V367 PolarHBondContact O-N 3.04Å; E364-V367 WeakPolarHBondContact O-CB 3.39Å; E364-V367 PolarHBondContact O-N 3.38Å; E364-V367 VanDerWaalsContact O-N 3.09Å; V367-V369 VanDerWaalsContact C-N 3.34Å; V367-V369 PolarHBondContact O-N 3.27Å; V367-G370 WeakPolarHBondContact O-CA 3.28Å; V367-G370 PolarHBondContact O-N 2.85Å; V367-G370 VanDerWaalsContact O-N 3.11Å; V367-C371 PolarHBondContact O-N 3.46Å; V367-C371 PolarHBondContact O-SG 2.95Å
368	E	82.9	Confident	87.9	Confident	84 Å²	84	51.5 Å²	51.5	39%	0.393	25%	0.25	S	S	.	.	H	α-helix	trans	-56.5	-47.3	175.2	-71.3	178	170.3	0	0	111.7	E364 R365 G370 C371 W372	E364-E368 WeakPolarHBondContact O-CG 3.47Å; E364-E368 PolarHBondContact O-N 3.24Å; R365-E368 VanDerWaalsContact CD-OE2 3.24Å; R365-E368 WeakPolarHBondContact CD-OE2 3.36Å; R365-E368 IonicContact CZ-OE2 2.7Å; R365-E368 IonicContact NE-OE2 3.03Å; R365-E368 IonicContact NH1-OE2 3.88Å; R365-E368 PolarHBondContact NH1-OE2 3.37Å; E368-G370 VanDerWaalsContact C-N 3.28Å; E368-G370 PolarHBondContact O-N 3.12Å; E368-C371 WeakPolarHBondContact O-CB 3.16Å; E368-C371 PolarHBondContact O-N 2.97Å; E368-C371 VanDerWaalsContact O-N 3.16Å; E368-W372 PolarHBondContact O-N 3.48Å
369	V	88	Confident	88	Confident	12 Å²	12	49.8 Å²	49.8	7%	0.073	24%	0.239	C	C	.	.	H	α-helix	trans	-69.1	-30.5	178.9	175.6	0	0	0	0	111.2	M342 Y347 R365 G366 V367 C371 W372 G373 V421 L425	M342-V369 HydrophobicContact CE-CG1 4.25Å; M342-V369 HydrophobicContact SD-CG1 4.47Å; Y347-V369 HydrophobicContact CE2-CB 3.96Å; Y347-V369 HydrophobicContact CE2-CG1 3.96Å; Y347-V369 HydrophobicContact CE2-CG2 4.27Å; Y347-V369 WeakPolarHBondContact OH-CG2 3.25Å; R365-V369 VanDerWaalsContact O-CG2 3.27Å; R365-V369 WeakPolarHBondContact O-CG2 3.47Å; R365-V369 PolarHBondContact O-N 3.43Å; R365-V369 VanDerWaalsContact O-N 3.09Å; G366-V369 PolarHBondContact O-N 3.03Å; V367-V369 VanDerWaalsContact C-N 3.34Å; V367-V369 PolarHBondContact O-N 3.27Å; V369-C371 VanDerWaalsContact C-N 3.34Å; V369-W372 WeakPolarHBondContact O-CB 3.13Å; V369-W372 PolarHBondContact O-N 3.27Å; V369-G373 PolarHBondContact O-N 2.8Å; V369-V421 HydrophobicContact CG1-CG1 3.98Å; V369-L425 HydrophobicContact CG1-CD1 4.08Å; V369-L425 HydrophobicContact CG1-CD2 4.09Å; V369-L425 HydrophobicContact CG1-CG 4.39Å
370	G	87.7	Confident	88.2	Confident	0 Å²	0	49.6 Å²	49.6	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-60.7	-41.6	169.6	0	0	0	0	0	112.1	F338 G366 V367 E368 W372 G373 L374	F338-G370 WeakPolarHBondContact CE1-O 3.26Å; G366-G370 PolarHBondContact O-N 2.86Å; V367-G370 WeakPolarHBondContact O-CA 3.28Å; V367-G370 PolarHBondContact O-N 2.85Å; V367-G370 VanDerWaalsContact O-N 3.11Å; E368-G370 VanDerWaalsContact C-N 3.28Å; E368-G370 PolarHBondContact O-N 3.12Å; G370-W372 VanDerWaalsContact C-N 3.34Å; G370-W372 PolarHBondContact O-N 3.39Å; G370-G373 WeakPolarHBondContact O-CA 3.49Å; G370-G373 PolarHBondContact O-N 3.26Å; G370-L374 PolarHBondContact O-N 3.42Å
371	C	83.7	Confident	88.6	Confident	44 Å²	44	48 Å²	48	30%	0.297	23%	0.23	S	C	.	.	H	α-helix	trans	-63.7	-39.1	175.9	-62.2	0	0	0	0	111.9	V367 E368 V369 G373 L374 C375	V367-C371 PolarHBondContact O-N 3.46Å; V367-C371 PolarHBondContact O-SG 2.95Å; E368-C371 WeakPolarHBondContact O-CB 3.16Å; E368-C371 PolarHBondContact O-N 2.97Å; E368-C371 VanDerWaalsContact O-N 3.16Å; V369-C371 VanDerWaalsContact C-N 3.34Å; C371-G373 VanDerWaalsContact C-N 3.29Å; C371-G373 PolarHBondContact O-N 2.71Å; C371-L374 PolarHBondContact O-N 3.06Å; C371-C375 PolarHBondContact O-N 3.28Å
372	W	87.7	Confident	88.9	Confident	140 Å²	140	44 Å²	44	53%	0.53	21%	0.211	S	C	.	.	H	α-helix	trans	-59.7	-39.8	169.9	-80.2	103.4	0	0	0	112.3	L196 E368 V369 G370 C375 I376	L196-W372 HydrophobicContact CD1-CH2 4.33Å; E368-W372 PolarHBondContact O-N 3.48Å; V369-W372 WeakPolarHBondContact O-CB 3.13Å; V369-W372 PolarHBondContact O-N 3.27Å; G370-W372 VanDerWaalsContact C-N 3.34Å; G370-W372 PolarHBondContact O-N 3.39Å; W372-C375 WeakPolarHBondContact O-CB 3.21Å; W372-C375 PolarHBondContact O-N 2.95Å; W372-I376 WeakPolarHBondContact O-CG1 3.47Å; W372-I376 PolarHBondContact O-N 2.91Å
373	G	90.6	Very high	89	Confident	0 Å²	0	45 Å²	45	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-59	-43.3	172	0	0	0	0	0	113.2	V369 G370 C371 C375 I376 N377 C428	V369-G373 PolarHBondContact O-N 2.8Å; G370-G373 WeakPolarHBondContact O-CA 3.49Å; G370-G373 PolarHBondContact O-N 3.26Å; C371-G373 VanDerWaalsContact C-N 3.29Å; C371-G373 PolarHBondContact O-N 2.71Å; G373-C375 VanDerWaalsContact C-N 3.34Å; G373-C375 PolarHBondContact O-N 3.46Å; G373-I376 WeakPolarHBondContact O-CB 3.33Å; G373-I376 PolarHBondContact O-N 2.78Å; G373-N377 PolarHBondContact O-N 3.39Å; G373-C428 WeakPolarHBondContact O-CB 3.37Å
374	L	88.1	Confident	89.3	Confident	15 Å²	15	44.3 Å²	44.3	8%	0.079	21%	0.213	C	C	.	.	H	α-helix	trans	-67.3	-33.6	176.3	-64.2	-179.2	0	0	0	112.9	Y195 M335 F338 T339 G370 C371 N377 S378	Y195-L374 HydrophobicContact CE2-CB 4.34Å; M335-L374 HydrophobicContact CE-CD2 4.16Å; M335-L374 HydrophobicContact SD-CD2 3.56Å; M335-L374 VanDerWaalsContact SD-CD2 3.56Å; F338-L374 HydrophobicContact CB-CD2 4.47Å; F338-L374 HydrophobicContact CD1-CD2 3.73Å; F338-L374 HydrophobicContact CD1-CG 3.97Å; F338-L374 HydrophobicContact CE1-CD2 4.43Å; F338-L374 HydrophobicContact CG-CD2 4.37Å; T339-L374 HydrophobicContact CG2-CD1 3.95Å; G370-L374 PolarHBondContact O-N 3.42Å; C371-L374 PolarHBondContact O-N 3.06Å; L374-N377 WeakPolarHBondContact O-CB 3.28Å; L374-N377 PolarHBondContact O-N 3.2Å; L374-S378 PolarHBondContact O-N 2.67Å; L374-S378 PolarHBondContact O-OG 2.87Å
375	C	89.6	Confident	89.6	Confident	19 Å²	19	40 Å²	40	13%	0.128	19%	0.193	C	C	.	.	H	α-helix	trans	-63.9	-47	170.9	-176.6	0	0	0	0	111.1	C371 W372 G373 N377 S378 V379	C371-C375 PolarHBondContact O-N 3.28Å; W372-C375 WeakPolarHBondContact O-CB 3.21Å; W372-C375 PolarHBondContact O-N 2.95Å; G373-C375 VanDerWaalsContact C-N 3.34Å; G373-C375 PolarHBondContact O-N 3.46Å; C375-N377 VanDerWaalsContact C-N 3.32Å; C375-N377 PolarHBondContact O-N 3.13Å; C375-S378 WeakPolarHBondContact O-CB 3.45Å; C375-S378 PolarHBondContact O-N 3.26Å; C375-V379 WeakPolarHBondContact O-CG2 3.4Å; C375-V379 PolarHBondContact O-N 3.4Å
376	I	92.3	Very high	89.7	Confident	54 Å²	54	40.9 Å²	40.9	28%	0.277	20%	0.198	S	C	.	.	H	α-helix	trans	-56.6	-46.6	174.8	-69.2	165.5	0	0	0	110.6	W372 G373 S378 V379 F380 L425 C428	W372-I376 WeakPolarHBondContact O-CG1 3.47Å; W372-I376 PolarHBondContact O-N 2.91Å; G373-I376 WeakPolarHBondContact O-CB 3.33Å; G373-I376 PolarHBondContact O-N 2.78Å; I376-S378 VanDerWaalsContact C-N 3.32Å; I376-S378 PolarHBondContact O-N 3.4Å; I376-V379 PolarHBondContact O-N 3.46Å; I376-F380 HydrophobicContact CG2-CD2 3.88Å; I376-F380 HydrophobicContact CG2-CE2 4.18Å; I376-F380 WeakPolarHBondContact O-CB 3.22Å; I376-F380 WeakPolarHBondContact O-CD2 3.33Å; I376-F380 PolarHBondContact O-N 3.27Å; I376-L425 HydrophobicContact CD1-CB 4.32Å; I376-L425 HydrophobicContact CD1-CD2 4.25Å; I376-C428 HydrophobicContact CB-CB 4.43Å; I376-C428 HydrophobicContact CG2-CB 4.24Å
377	N	92.8	Very high	89.8	Confident	8 Å²	8	46.1 Å²	46.1	4%	0.043	22%	0.221	C	C	.	.	H	α-helix	trans	-53.3	-47.7	173.6	158.2	69.8	0	0	0	111.9	G373 L374 C375 F380 S381 C428 F431 G432	G373-N377 PolarHBondContact O-N 3.39Å; L374-N377 WeakPolarHBondContact O-CB 3.28Å; L374-N377 PolarHBondContact O-N 3.2Å; C375-N377 VanDerWaalsContact C-N 3.32Å; C375-N377 PolarHBondContact O-N 3.13Å; N377-F380 PolarHBondContact O-N 3.48Å; N377-S381 WeakPolarHBondContact O-CB 3.46Å; N377-S381 PolarHBondContact O-N 2.92Å; N377-C428 WeakPolarHBondContact CA-O 3.45Å; N377-F431 HydrophobicContact CB-CB 4.1Å; N377-F431 WeakPolarHBondContact OD1-CB 3.37Å; N377-F431 PolarHBondContact OD1-O 2.98Å; N377-G432 VanDerWaalsContact O-CA 3.22Å; N377-G432 WeakPolarHBondContact O-CA 3.3Å; N377-G432 WeakPolarHBondContact OD1-CA 3.35Å; N377-G432 PolarHBondContact OD1-N 3.44Å
378	S	91.7	Very high	90.1	Very high	10 Å²	10	44.2 Å²	44.2	7%	0.07	21%	0.209	C	C	.	.	H	α-helix	trans	-66.2	-42.3	-177.9	-55.9	0	0	0	0	112.1	G188 L374 C375 I376 S381 S382	G188-S378 CarbonylContact C-O 3.57Å; G188-S378 WeakPolarHBondContact CA-O 3.34Å; G188-S378 CarbonylContact O-C 3.46Å; G188-S378 WeakPolarHBondContact O-CB 3.44Å; L374-S378 PolarHBondContact O-N 2.67Å; L374-S378 PolarHBondContact O-OG 2.87Å; C375-S378 WeakPolarHBondContact O-CB 3.45Å; C375-S378 PolarHBondContact O-N 3.26Å; I376-S378 VanDerWaalsContact C-N 3.32Å; I376-S378 PolarHBondContact O-N 3.4Å; S378-S381 PolarHBondContact O-N 2.69Å; S378-S382 PolarHBondContact O-N 2.8Å
379	V	93.9	Very high	90.2	Very high	61 Å²	61	46.4 Å²	46.4	37%	0.37	22%	0.217	S	C	.	.	H	α-helix	trans	-62.5	-47.4	174.5	173.6	0	0	0	0	111	A192 C375 I376 S381 S382 L383	A192-V379 HydrophobicContact CB-CG2 3.74Å; C375-V379 WeakPolarHBondContact O-CG2 3.4Å; C375-V379 PolarHBondContact O-N 3.4Å; I376-V379 PolarHBondContact O-N 3.46Å; V379-S381 PolarHBondContact O-N 3.23Å; V379-S382 WeakPolarHBondContact O-CB 3.34Å; V379-S382 PolarHBondContact O-N 3.46Å; V379-L383 HydrophobicContact CG1-CD1 4.08Å; V379-L383 HydrophobicContact CG1-CG 4.49Å; V379-L383 WeakPolarHBondContact O-CG 3.09Å; V379-L383 PolarHBondContact O-N 2.92Å
380	F	94.2	Very high	90.2	Very high	93 Å²	93	49.5 Å²	49.5	41%	0.408	24%	0.236	S	C	.	.	H	α-helix	trans	-67.4	-35	178.5	-93.7	-96.1	0	0	0	112.7	I376 N377 S382 L383 Y384 S429	I376-F380 HydrophobicContact CG2-CD2 3.88Å; I376-F380 HydrophobicContact CG2-CE2 4.18Å; I376-F380 WeakPolarHBondContact O-CB 3.22Å; I376-F380 WeakPolarHBondContact O-CD2 3.33Å; I376-F380 PolarHBondContact O-N 3.27Å; N377-F380 PolarHBondContact O-N 3.48Å; F380-S382 VanDerWaalsContact C-N 3.31Å; F380-S382 PolarHBondContact O-N 3.35Å; F380-L383 PolarHBondContact O-N 2.88Å; F380-Y384 WeakPolarHBondContact O-CB 3.39Å; F380-Y384 PolarHBondContact O-N 3.49Å; F380-S429 VanDerWaalsContact CD1-CB 3.5Å
381	S	93.4	Very high	90.4	Very high	0 Å²	0	52.1 Å²	52.1	0%	0	25%	0.25	C	C	.	.	H	α-helix	trans	-59.4	-44.4	172	-178.2	0	0	0	0	111.3	N377 S378 V379 S385 G432 S436	N377-S381 WeakPolarHBondContact O-CB 3.46Å; N377-S381 PolarHBondContact O-N 2.92Å; S378-S381 PolarHBondContact O-N 2.69Å; V379-S381 PolarHBondContact O-N 3.23Å; S381-S385 WeakPolarHBondContact O-CB 3.26Å; S381-S385 PolarHBondContact O-N 3.24Å; S381-S385 PolarHBondContact O-OG 2.93Å; S381-G432 VanDerWaalsContact CA-O 3.31Å; S381-G432 WeakPolarHBondContact CA-O 3.39Å; S381-G432 WeakPolarHBondContact CB-O 3.32Å; S381-S436 WeakPolarHBondContact O-CB 3.42Å; S381-S436 WeakPolarHBondContact OG-CB 3.49Å; S381-S436 PolarHBondContact OG-N 3.46Å
382	S	92.2	Very high	90.6	Very high	12 Å²	12	51.8 Å²	51.8	8%	0.084	25%	0.246	C	C	.	.	H	α-helix	trans	-60.7	-54.3	175.4	169.8	0	0	0	0	111.1	L185 S378 V379 F380 Y384 S385 Y386	L185-S382 WeakPolarHBondContact CD1-O 3.39Å; L185-S382 WeakPolarHBondContact CD1-OG 3.48Å; L185-S382 WeakPolarHBondContact O-CB 3.18Å; L185-S382 PolarHBondContact O-OG 3.3Å; S378-S382 PolarHBondContact O-N 2.8Å; V379-S382 WeakPolarHBondContact O-CB 3.34Å; V379-S382 PolarHBondContact O-N 3.46Å; F380-S382 VanDerWaalsContact C-N 3.31Å; F380-S382 PolarHBondContact O-N 3.35Å; S382-Y384 PolarHBondContact O-N 2.95Å; S382-S385 WeakPolarHBondContact O-CB 3.36Å; S382-S385 PolarHBondContact O-N 3.29Å; S382-Y386 PolarHBondContact O-N 2.94Å
383	L	92.7	Very high	90.6	Very high	85 Å²	85	49.6 Å²	49.6	45%	0.445	25%	0.252	S	S	.	.	H	α-helix	trans	-60.1	-45.5	179.7	-67.2	174.8	0	0	0	112.3	V379 F380 S385 Y386 F387	V379-L383 HydrophobicContact CG1-CD1 4.08Å; V379-L383 HydrophobicContact CG1-CG 4.49Å; V379-L383 WeakPolarHBondContact O-CG 3.09Å; V379-L383 PolarHBondContact O-N 2.92Å; F380-L383 PolarHBondContact O-N 2.88Å; L383-S385 VanDerWaalsContact C-N 3.33Å; L383-S385 PolarHBondContact O-N 3.47Å; L383-Y386 WeakPolarHBondContact O-CB 3.47Å; L383-Y386 PolarHBondContact O-N 3.22Å; L383-Y386 VanDerWaalsContact O-N 3.17Å; L383-F387 WeakPolarHBondContact O-CD2 3.25Å; L383-F387 PolarHBondContact O-N 2.78Å
384	Y	93.2	Very high	90.6	Very high	28 Å²	28	58.6 Å²	58.6	11%	0.11	29%	0.288	C	S	.	.	H	α-helix	trans	-61.2	-42.1	178.9	-172.8	-109	0	0	0	111.4	F380 S382 Y386 F387 Q388 L391 L400 V433 S436	F380-Y384 WeakPolarHBondContact O-CB 3.39Å; F380-Y384 PolarHBondContact O-N 3.49Å; S382-Y384 PolarHBondContact O-N 2.95Å; Y384-Y386 PolarHBondContact O-N 2.9Å; Y384-F387 CarbonylContact O-C 3.55Å; Y384-F387 PolarHBondContact O-N 2.9Å; Y384-Q388 HydrophobicContact CD1-CG 3.68Å; Y384-Q388 HydrophobicContact CE1-CG 3.57Å; Y384-Q388 HydrophobicContact CG-CG 4.41Å; Y384-Q388 WeakPolarHBondContact O-CG 3.23Å; Y384-Q388 PolarHBondContact O-N 2.91Å; Y384-L391 HydrophobicContact CE2-CD2 3.67Å; Y384-L400 HydrophobicContact CE1-CD1 4.39Å; Y384-L400 WeakPolarHBondContact OH-CD1 3.35Å; Y384-V433 HydrophobicContact CD1-CB 4.45Å; Y384-V433 HydrophobicContact CD1-CG1 4.21Å; Y384-V433 HydrophobicContact CD2-CG1 4.47Å; Y384-V433 HydrophobicContact CD2-CG2 4.07Å; Y384-V433 HydrophobicContact CE1-CB 4.45Å; Y384-V433 HydrophobicContact CE1-CG1 3.74Å; Y384-V433 HydrophobicContact CE2-CG1 4.04Å; Y384-V433 HydrophobicContact CE2-CG2 4.3Å; Y384-V433 HydrophobicContact CG-CG2 4.21Å; Y384-S436 WeakPolarHBondContact CD1-OG 3.33Å
385	S	89.6	Confident	90.8	Very high	1 Å²	1	61 Å²	61	1%	0.007	30%	0.3	C	S	.	.	H	α-helix	trans	-56.3	-35.2	176.6	-59.8	0	0	0	0	112.9	A184 S381 S382 L383 S436	A184-S385 VanDerWaalsContact CB-OG 3.29Å; A184-S385 WeakPolarHBondContact CB-OG 3.34Å; S381-S385 WeakPolarHBondContact O-CB 3.26Å; S381-S385 PolarHBondContact O-N 3.24Å; S381-S385 PolarHBondContact O-OG 2.93Å; S382-S385 WeakPolarHBondContact O-CB 3.36Å; S382-S385 PolarHBondContact O-N 3.29Å; L383-S385 VanDerWaalsContact C-N 3.33Å; L383-S385 PolarHBondContact O-N 3.47Å; S385-S436 WeakPolarHBondContact CA-OG 3.47Å; S385-S436 PolarHBondContact N-OG 3.1Å; S385-S436 WeakPolarHBondContact OG-CB 3.49Å; S385-S436 PolarHBondContact OG-OG 3.42Å
386	Y	87.9	Confident	90.9	Very high	154 Å²	154	60.7 Å²	60.7	60%	0.604	30%	0.3	S	S	*	.	H	α-helix	trans	-68	-42.1	174.3	-176.4	-100.2	0	0	0	112.3	S382 L383 Y384	S382-Y386 PolarHBondContact O-N 2.94Å; L383-Y386 WeakPolarHBondContact O-CB 3.47Å; L383-Y386 PolarHBondContact O-N 3.22Å; L383-Y386 VanDerWaalsContact O-N 3.17Å; Y384-Y386 PolarHBondContact O-N 2.9Å
387	F	90.4	Very high	90.9	Very high	109 Å²	109	59 Å²	59	48%	0.478	29%	0.291	S	S	.	.	H	α-helix	trans	-79.6	-19.1	179.7	-66.3	-66.1	0	0	0	114	L383 Y384 K389 V390 L391	L383-F387 WeakPolarHBondContact O-CD2 3.25Å; L383-F387 PolarHBondContact O-N 2.78Å; Y384-F387 CarbonylContact O-C 3.55Å; Y384-F387 PolarHBondContact O-N 2.9Å; F387-K389 PolarHBondContact O-N 3.4Å; F387-K389 VanDerWaalsContact O-N 3.15Å; F387-V390 WeakPolarHBondContact O-CB 3.38Å; F387-V390 PolarHBondContact O-N 2.92Å; F387-L391 HydrophobicContact CB-CD1 4.36Å; F387-L391 WeakPolarHBondContact O-CD1 3.34Å; F387-L391 PolarHBondContact O-N 3.44Å; F387-L391 VanDerWaalsContact O-N 3.08Å
388	Q	89.3	Confident	90.9	Very high	0 Å²	0	60.7 Å²	60.7	0%	0	30%	0.298	C	S	.	.	H	α-helix	trans	-52.3	-40.3	-179.9	-85.1	-176.9	-20.5	0	0	112	H181 Y384 V390 L391 V392 L400 S436 T440	H181-Q388 PolarHBondContact ND1-OE1 3.45Å; Y384-Q388 HydrophobicContact CD1-CG 3.68Å; Y384-Q388 HydrophobicContact CE1-CG 3.57Å; Y384-Q388 HydrophobicContact CG-CG 4.41Å; Y384-Q388 WeakPolarHBondContact O-CG 3.23Å; Y384-Q388 PolarHBondContact O-N 2.91Å; Q388-V390 PolarHBondContact O-N 2.89Å; Q388-L391 CarbonylContact O-C 3.58Å; Q388-L391 PolarHBondContact O-N 3.16Å; Q388-L391 VanDerWaalsContact O-N 3.08Å; Q388-V392 VanDerWaalsContact O-CG2 3.29Å; Q388-V392 WeakPolarHBondContact O-CG2 3.44Å; Q388-V392 PolarHBondContact O-N 3.26Å; Q388-L400 HydrophobicContact CB-CD2 4.21Å; Q388-L400 HydrophobicContact CG-CD2 3.94Å; Q388-S436 VanDerWaalsContact CD-OG 3.25Å; Q388-S436 PolarHBondContact NE2-O 3.43Å; Q388-S436 PolarHBondContact NE2-OG 2.86Å; Q388-S436 PolarHBondContact OE1-OG 2.71Å; Q388-T440 VanDerWaalsContact CD-OG1 3.25Å; Q388-T440 PolarHBondContact NE2-OG1 3.45Å; Q388-T440 VanDerWaalsContact OE1-CG2 3.25Å; Q388-T440 PolarHBondContact OE1-OG1 3.22Å
389	K	84.6	Confident	91	Very high	130 Å²	130	61.1 Å²	61.1	57%	0.565	30%	0.304	S	S	*	.	H	α-helix	trans	-56.1	-40.2	177.7	-174.4	-176.5	178	-169.1	0	112.6	F387	F387-K389 PolarHBondContact O-N 3.4Å; F387-K389 VanDerWaalsContact O-N 3.15Å
390	V	89.4	Confident	90.9	Very high	77 Å²	77	58.3 Å²	58.3	47%	0.467	29%	0.287	S	S	.	.	H	α-helix	trans	-70	-46.7	176.8	177.6	0	0	0	0	109.4	F387 Q388 V392 S393 Y394	F387-V390 WeakPolarHBondContact O-CB 3.38Å; F387-V390 PolarHBondContact O-N 2.92Å; Q388-V390 PolarHBondContact O-N 2.89Å; V390-V392 PolarHBondContact O-N 3.34Å; V390-S393 PolarHBondContact O-N 3.28Å; V390-S393 PolarHBondContact O-OG 3.14Å; V390-Y394 HydrophobicContact CG1-CD2 4.24Å; V390-Y394 HydrophobicContact CG1-CE2 3.69Å; V390-Y394 WeakPolarHBondContact O-CD2 3.41Å
391	L	90.9	Very high	91	Very high	55 Å²	55	53.9 Å²	53.9	29%	0.288	27%	0.268	S	S	.	.	H	α-helix	trans	-61.5	-41	179.6	-88.9	66.1	0	0	0	112.9	Y384 F387 Q388 S393 Y394 I395 L400	Y384-L391 HydrophobicContact CE2-CD2 3.67Å; F387-L391 HydrophobicContact CB-CD1 4.36Å; F387-L391 WeakPolarHBondContact O-CD1 3.34Å; F387-L391 PolarHBondContact O-N 3.44Å; F387-L391 VanDerWaalsContact O-N 3.08Å; Q388-L391 CarbonylContact O-C 3.58Å; Q388-L391 PolarHBondContact O-N 3.16Å; Q388-L391 VanDerWaalsContact O-N 3.08Å; L391-S393 PolarHBondContact O-N 3.05Å; L391-Y394 PolarHBondContact O-N 3.49Å; L391-I395 WeakPolarHBondContact O-CG1 3.31Å; L391-I395 PolarHBondContact O-N 3.44Å; L391-L400 HydrophobicContact CB-CD1 4.02Å; L391-L400 HydrophobicContact CD2-CD1 4.08Å
392	V	88.8	Confident	91.1	Very high	36 Å²	36	57.3 Å²	57.3	22%	0.218	28%	0.283	C	S	.	.	H	α-helix	trans	-55.4	-37.2	177.6	170.3	0	0	0	0	110.9	Q388 V390 Y394 G396 L397 L400	Q388-V392 VanDerWaalsContact O-CG2 3.29Å; Q388-V392 WeakPolarHBondContact O-CG2 3.44Å; Q388-V392 PolarHBondContact O-N 3.26Å; V390-V392 PolarHBondContact O-N 3.34Å; V392-Y394 PolarHBondContact O-N 3.49Å; V392-G396 VanDerWaalsContact O-CA 3.22Å; V392-G396 WeakPolarHBondContact O-CA 3.36Å; V392-G396 PolarHBondContact O-N 3.15Å; V392-L397 HydrophobicContact CG1-CD2 4.19Å; V392-L397 HydrophobicContact CG1-CG 4.3Å; V392-L397 HydrophobicContact CG2-CD2 4.09Å; V392-L400 HydrophobicContact CG2-CD2 3.56Å
393	S	88.2	Confident	91.2	Very high	94 Å²	94	58.8 Å²	58.8	66%	0.657	29%	0.291	S	S	*	.	H	α-helix	trans	-67.9	-19.2	177.7	72.3	0	0	0	0	114.6	V390 L391	V390-S393 PolarHBondContact O-N 3.28Å; V390-S393 PolarHBondContact O-OG 3.14Å; L391-S393 PolarHBondContact O-N 3.05Å
394	Y	90.6	Very high	91.3	Very high	190 Å²	190	54.7 Å²	54.7	75%	0.745	27%	0.27	S	S	*	.	H	α-helix	trans	-99	-40.4	-179.9	-69.7	-74.2	0	0	0	113.7	V390 L391 V392	V390-Y394 HydrophobicContact CG1-CD2 4.24Å; V390-Y394 HydrophobicContact CG1-CE2 3.69Å; V390-Y394 WeakPolarHBondContact O-CD2 3.41Å; L391-Y394 PolarHBondContact O-N 3.49Å; V392-Y394 PolarHBondContact O-N 3.49Å
395	I	92	Very high	91.5	Very high	66 Å²	66	53.4 Å²	53.4	34%	0.338	27%	0.265	S	S	.	.	H	α-helix	trans	-117.1	-3.2	-172.6	63.2	174.6	0	0	0	113.9	L391 G399 L400	L391-I395 WeakPolarHBondContact O-CG1 3.31Å; L391-I395 PolarHBondContact O-N 3.44Å; I395-G399 WeakPolarHBondContact O-CA 3.36Å; I395-G399 PolarHBondContact O-N 2.9Å; I395-L400 HydrophobicContact CD1-CB 4.22Å; I395-L400 HydrophobicContact CD1-CD1 4.13Å; I395-L400 HydrophobicContact CG1-CB 4.46Å
396	G	91.4	Very high	91.8	Very high	12 Å²	12	56.1 Å²	56.1	12%	0.124	28%	0.279	C	S	.	.	H	α-helix	trans	69.5	173.6	-175.2	0	0	0	0	0	113.7	V392 G399 L400	V392-G396 VanDerWaalsContact O-CA 3.22Å; V392-G396 WeakPolarHBondContact O-CA 3.36Å; V392-G396 PolarHBondContact O-N 3.15Å; G396-G399 PolarHBondContact O-N 3.21Å; G396-L400 WeakPolarHBondContact O-CB 3.48Å; G396-L400 PolarHBondContact O-N 2.88Å
397	L	91.2	Very high	92.3	Very high	19 Å²	19	51.6 Å²	51.6	10%	0.099	27%	0.265	C	S	.	.	H	α-helix	trans	-65.4	-43.1	179.6	-72.7	170.6	0	0	0	112.2	V392 L400 Y401 V441 N444 L445	V392-L397 HydrophobicContact CG1-CD2 4.19Å; V392-L397 HydrophobicContact CG1-CG 4.3Å; V392-L397 HydrophobicContact CG2-CD2 4.09Å; L397-L400 PolarHBondContact O-N 3.31Å; L397-Y401 PolarHBondContact O-N 3.46Å; L397-V441 HydrophobicContact CB-CG1 4.38Å; L397-V441 HydrophobicContact CD2-CG1 4.42Å; L397-V441 WeakPolarHBondContact O-CG1 3.32Å; L397-N444 HydrophobicContact CD1-CB 4.21Å; L397-N444 HydrophobicContact CD2-CB 3.85Å; L397-L445 HydrophobicContact CB-CD2 3.86Å; L397-L445 HydrophobicContact CB-CG 4.27Å; L397-L445 HydrophobicContact CD1-CD2 4.11Å; L397-L445 HydrophobicContact CD1-CG 4.46Å
398	K	93.2	Very high	92.5	Very high	43 Å²	43	46.4 Å²	46.4	19%	0.187	24%	0.242	C	C	.	.	H	α-helix	trans	-63	-43.8	177.9	-178.1	179.2	177.7	168	0	111.7	Y401 F402 V522 A523 V526 Y528	K398-Y401 PolarHBondContact O-N 3.39Å; K398-F402 WeakPolarHBondContact O-CB 3.37Å; K398-F402 PolarHBondContact O-N 2.87Å; K398-V522 WeakPolarHBondContact CE-O 3.4Å; K398-V522 HydrophobicContact CG-CG1 4.48Å; K398-A523 VanDerWaalsContact CE-O 3.27Å; K398-A523 WeakPolarHBondContact CE-O 3.43Å; K398-A523 PolarHBondContact NZ-O 3.48Å; K398-V526 VanDerWaalsContact CD-O 3.31Å; K398-V526 WeakPolarHBondContact CD-O 3.21Å; K398-V526 WeakPolarHBondContact CE-O 3.48Å; K398-V526 HydrophobicContact CG-CG1 4.38Å; K398-V526 PolarHBondContact NZ-O 3.16Å; K398-Y528 HydrophobicContact CB-CD2 4.17Å; K398-Y528 HydrophobicContact CD-CD2 4.15Å
399	G	93.2	Very high	92.9	Very high	19 Å²	19	46.4 Å²	46.4	20%	0.196	24%	0.242	C	C	.	.	H	α-helix	trans	-63.3	-43.3	177.2	0	0	0	0	0	111.5	I395 G396 Y401 F402 T403	I395-G399 WeakPolarHBondContact O-CA 3.36Å; I395-G399 PolarHBondContact O-N 2.9Å; G396-G399 PolarHBondContact O-N 3.21Å; G399-Y401 VanDerWaalsContact C-N 3.29Å; G399-Y401 PolarHBondContact O-N 3.33Å; G399-F402 WeakPolarHBondContact O-CB 3.44Å; G399-F402 PolarHBondContact O-N 3.44Å; G399-T403 WeakPolarHBondContact O-CB 3.42Å; G399-T403 PolarHBondContact O-N 2.87Å; G399-T403 PolarHBondContact O-OG1 3.31Å
400	L	93.6	Very high	93.4	Very high	1 Å²	1	45 Å²	45	1%	0.005	24%	0.24	C	C	.	.	H	α-helix	trans	-59.1	-42.5	175.2	-169.6	67.6	0	0	0	111.8	Y384 Q388 L391 V392 I395 G396 L397 T403 G404 V441	Y384-L400 HydrophobicContact CE1-CD1 4.39Å; Y384-L400 WeakPolarHBondContact OH-CD1 3.35Å; Q388-L400 HydrophobicContact CB-CD2 4.21Å; Q388-L400 HydrophobicContact CG-CD2 3.94Å; L391-L400 HydrophobicContact CB-CD1 4.02Å; L391-L400 HydrophobicContact CD2-CD1 4.08Å; V392-L400 HydrophobicContact CG2-CD2 3.56Å; I395-L400 HydrophobicContact CD1-CB 4.22Å; I395-L400 HydrophobicContact CD1-CD1 4.13Å; I395-L400 HydrophobicContact CG1-CB 4.46Å; G396-L400 WeakPolarHBondContact O-CB 3.48Å; G396-L400 PolarHBondContact O-N 2.88Å; L397-L400 PolarHBondContact O-N 3.31Å; L400-T403 PolarHBondContact O-N 3.01Å; L400-G404 PolarHBondContact O-N 3.05Å; L400-V441 HydrophobicContact CB-CG2 4.29Å; L400-V441 HydrophobicContact CD2-CG2 3.51Å; L400-V441 HydrophobicContact CG-CG2 3.9Å
401	Y	94.6	Very high	93.7	Very high	0 Å²	0	41.5 Å²	41.5	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-63.1	-48	178.3	-156.6	-171.5	0	0	0	111.6	L320 S323 H324 L397 K398 G399 T403 G404 Y405 T437 L438 V441 P442 L445 V522 V526	L320-Y401 HydrophobicContact CD1-CE1 4.2Å; S323-Y401 WeakPolarHBondContact OG-CE1 3.24Å; H324-Y401 WeakPolarHBondContact CA-OH 3.37Å; H324-Y401 PolarHBondContact N-OH 3.2Å; L397-Y401 PolarHBondContact O-N 3.46Å; K398-Y401 PolarHBondContact O-N 3.39Å; G399-Y401 VanDerWaalsContact C-N 3.29Å; G399-Y401 PolarHBondContact O-N 3.33Å; Y401-T403 PolarHBondContact O-N 3.02Å; Y401-G404 PolarHBondContact O-N 2.94Å; Y401-Y405 AromaticContact CD2-CD2 3.89Å; Y401-Y405 HydrophobicContact CD2-CD2 3.89Å; Y401-Y405 AromaticContact CD2-CE2 3.5Å; Y401-Y405 HydrophobicContact CD2-CE2 3.5Å; Y401-Y405 VanDerWaalsContact CD2-CE2 3.5Å; Y401-Y405 HydrophobicContact CE1-CE2 4.19Å; Y401-Y405 AromaticContact CE2-CD2 3.99Å; Y401-Y405 HydrophobicContact CE2-CD2 3.99Å; Y401-Y405 AromaticContact CE2-CE2 3.15Å; Y401-Y405 HydrophobicContact CE2-CE2 3.15Å; Y401-Y405 AromaticContact CE2-CZ 3.89Å; Y401-Y405 HydrophobicContact CG-CE2 4.2Å; Y401-Y405 AromaticContact CZ-CE2 3.51Å; Y401-Y405 VanDerWaalsContact O-CD2 3.29Å; Y401-Y405 WeakPolarHBondContact O-CD2 3.43Å; Y401-Y405 PolarHBondContact O-N 3.49Å; Y401-Y405 PolarHBondContact OH-OH 3.31Å; Y401-T437 HydrophobicContact CD2-CG2 3.65Å; Y401-T437 HydrophobicContact CE2-CG2 4.33Å; Y401-L438 HydrophobicContact CE2-CD2 4.06Å; Y401-V441 HydrophobicContact CD1-CG1 4.47Å; Y401-V441 HydrophobicContact CG-CG1 4.08Å; Y401-P442 HydrophobicContact CE1-CG 4.26Å; Y401-P442 HydrophobicContact CE2-CG 4.15Å; Y401-L445 HydrophobicContact CD1-CD1 4.31Å; Y401-V522 HydrophobicContact CD1-CG1 3.95Å; Y401-V522 HydrophobicContact CD1-CG2 3.68Å; Y401-V522 HydrophobicContact CE1-CG2 3.82Å; Y401-V522 HydrophobicContact CG-CG1 4.1Å; Y401-V522 HydrophobicContact CG-CG2 4.09Å; Y401-V526 HydrophobicContact CD1-CG2 4.5Å
402	F	95.7	Very high	93.8	Very high	73 Å²	73	38.9 Å²	38.9	32%	0.32	21%	0.205	S	C	.	.	H	α-helix	trans	-57	-48.3	176.5	173	-90.7	0	0	0	111.9	K398 G399 G404 Y405 L406 C519 V522 A523	K398-F402 WeakPolarHBondContact O-CB 3.37Å; K398-F402 PolarHBondContact O-N 2.87Å; G399-F402 WeakPolarHBondContact O-CB 3.44Å; G399-F402 PolarHBondContact O-N 3.44Å; F402-G404 VanDerWaalsContact C-N 3.31Å; F402-G404 PolarHBondContact O-N 3.36Å; F402-Y405 PolarHBondContact O-N 3.01Å; F402-L406 HydrophobicContact CE1-CD2 3.91Å; F402-L406 HydrophobicContact CZ-CD2 4.34Å; F402-L406 WeakPolarHBondContact O-CB 3.24Å; F402-L406 PolarHBondContact O-N 3.27Å; F402-C519 WeakPolarHBondContact CD2-SG 3.47Å; F402-C519 WeakPolarHBondContact CE2-SG 3.4Å; F402-V522 HydrophobicContact CB-CG1 4.16Å; F402-A523 HydrophobicContact CD2-CB 3.92Å; F402-A523 HydrophobicContact CE2-CB 4.01Å
403	T	94.8	Very high	94.1	Very high	42 Å²	42	37.8 Å²	37.8	26%	0.258	20%	0.202	S	C	.	.	H	α-helix	trans	-60.5	-39.9	179.1	-61.9	0	0	0	0	111.8	G399 L400 Y401 L406 L407	G399-T403 WeakPolarHBondContact O-CB 3.42Å; G399-T403 PolarHBondContact O-N 2.87Å; G399-T403 PolarHBondContact O-OG1 3.31Å; L400-T403 PolarHBondContact O-N 3.01Å; Y401-T403 PolarHBondContact O-N 3.02Å; T403-L406 PolarHBondContact O-N 3.44Å; T403-L407 HydrophobicContact CG2-CD1 3.65Å; T403-L407 HydrophobicContact CG2-CG 4.08Å; T403-L407 WeakPolarHBondContact O-CB 3.48Å; T403-L407 VanDerWaalsContact O-CG 3.31Å; T403-L407 WeakPolarHBondContact O-CG 3.34Å; T403-L407 PolarHBondContact O-N 2.76Å
404	G	95.2	Very high	94.4	Very high	0 Å²	0	38 Å²	38	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-58.5	-49.2	175.7	0	0	0	0	0	112.9	L400 Y401 F402 F408	L400-G404 PolarHBondContact O-N 3.05Å; Y401-G404 PolarHBondContact O-N 2.94Å; F402-G404 VanDerWaalsContact C-N 3.31Å; F402-G404 PolarHBondContact O-N 3.36Å; G404-F408 WeakPolarHBondContact O-CB 3.48Å; G404-F408 PolarHBondContact O-N 3.46Å; G404-F408 VanDerWaalsContact O-N 3.11Å
405	Y	96.9	Very high	94.5	Very high	0 Å²	0	29 Å²	29	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-61.9	-45.7	175.4	-82.5	-83.1	0	0	0	113	S323 I326 G327 Y401 F402 F408 G409 M434 A515 V522	S323-Y405 PolarHBondContact O-OH 3.3Å; I326-Y405 HydrophobicContact CG2-CE1 4.38Å; G327-Y405 WeakPolarHBondContact CA-OH 3.43Å; G327-Y405 PolarHBondContact N-OH 2.93Å; Y401-Y405 AromaticContact CD2-CD2 3.89Å; Y401-Y405 HydrophobicContact CD2-CD2 3.89Å; Y401-Y405 AromaticContact CD2-CE2 3.5Å; Y401-Y405 HydrophobicContact CD2-CE2 3.5Å; Y401-Y405 VanDerWaalsContact CD2-CE2 3.5Å; Y401-Y405 HydrophobicContact CE1-CE2 4.19Å; Y401-Y405 AromaticContact CE2-CD2 3.99Å; Y401-Y405 HydrophobicContact CE2-CD2 3.99Å; Y401-Y405 AromaticContact CE2-CE2 3.15Å; Y401-Y405 HydrophobicContact CE2-CE2 3.15Å; Y401-Y405 AromaticContact CE2-CZ 3.89Å; Y401-Y405 HydrophobicContact CG-CE2 4.2Å; Y401-Y405 AromaticContact CZ-CE2 3.51Å; Y401-Y405 VanDerWaalsContact O-CD2 3.29Å; Y401-Y405 WeakPolarHBondContact O-CD2 3.43Å; Y401-Y405 PolarHBondContact O-N 3.49Å; Y401-Y405 PolarHBondContact OH-OH 3.31Å; F402-Y405 PolarHBondContact O-N 3.01Å; Y405-F408 PolarHBondContact O-N 2.97Å; Y405-G409 PolarHBondContact O-N 3.05Å; Y405-M434 HydrophobicContact CD1-CE 3.56Å; Y405-M434 HydrophobicContact CE1-CE 3.84Å; Y405-M434 HydrophobicContact CG-CE 4.07Å; Y405-A515 HydrophobicContact CD1-CB 4.49Å; Y405-A515 VanDerWaalsContact CD1-O 3.26Å; Y405-A515 WeakPolarHBondContact CD1-O 3.4Å; Y405-V522 HydrophobicContact CD2-CG2 3.78Å; Y405-V522 HydrophobicContact CE2-CG2 3.5Å
406	L	97	Very high	94.5	Very high	59 Å²	59	26.4 Å²	26.4	31%	0.309	15%	0.145	S	C	.	.	H	α-helix	trans	-62.1	-50.7	-176.8	-176.9	64.1	0	0	0	111	F402 T403 F408 G409 L410 L516	F402-L406 HydrophobicContact CE1-CD2 3.91Å; F402-L406 HydrophobicContact CZ-CD2 4.34Å; F402-L406 WeakPolarHBondContact O-CB 3.24Å; F402-L406 PolarHBondContact O-N 3.27Å; T403-L406 PolarHBondContact O-N 3.44Å; L406-F408 VanDerWaalsContact C-N 3.32Å; L406-F408 PolarHBondContact O-N 3.1Å; L406-G409 PolarHBondContact O-N 3.47Å; L406-L410 HydrophobicContact CD1-CD1 3.99Å; L406-L410 HydrophobicContact CD1-CG 4.19Å; L406-L410 HydrophobicContact CG-CD1 3.99Å; L406-L410 HydrophobicContact CG-CG 4.49Å; L406-L410 WeakPolarHBondContact O-CB 3.19Å; L406-L410 VanDerWaalsContact O-CG 3.28Å; L406-L410 WeakPolarHBondContact O-CG 3.2Å; L406-L410 PolarHBondContact O-N 2.68Å; L406-L516 HydrophobicContact CD1-CD2 4.31Å
407	L	96.4	Very high	94.4	Very high	59 Å²	59	31.9 Å²	31.9	31%	0.309	17%	0.171	S	C	.	.	H	α-helix	trans	-62.9	-40.4	-179.4	-71.6	177.9	0	0	0	111.5	T403 G411 L430 V433	T403-L407 HydrophobicContact CG2-CD1 3.65Å; T403-L407 HydrophobicContact CG2-CG 4.08Å; T403-L407 WeakPolarHBondContact O-CB 3.48Å; T403-L407 VanDerWaalsContact O-CG 3.31Å; T403-L407 WeakPolarHBondContact O-CG 3.34Å; T403-L407 PolarHBondContact O-N 2.76Å; L407-G411 PolarHBondContact O-N 3Å; L407-L430 HydrophobicContact CB-CD2 4.35Å; L407-V433 HydrophobicContact CD1-CG1 4.03Å
408	F	96.6	Very high	94.5	Very high	0 Å²	0	36.6 Å²	36.6	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-65.7	-46.6	175.6	-173.8	-100.6	0	0	0	112.7	A330 F331 N334 G404 Y405 L406 G411 T412 F431 M434 A511 A515	A330-F408 HydrophobicContact CB-CE1 4.05Å; F331-F408 HydrophobicContact CD2-CD2 4.49Å; F331-F408 AromaticContact CD2-CE2 3.87Å; F331-F408 HydrophobicContact CD2-CE2 3.87Å; F331-F408 HydrophobicContact CD2-CZ 4.22Å; F331-F408 HydrophobicContact CE2-CE2 4.48Å; N334-F408 HydrophobicContact CB-CZ 3.89Å; G404-F408 WeakPolarHBondContact O-CB 3.48Å; G404-F408 PolarHBondContact O-N 3.46Å; G404-F408 VanDerWaalsContact O-N 3.11Å; Y405-F408 PolarHBondContact O-N 2.97Å; L406-F408 VanDerWaalsContact C-N 3.32Å; L406-F408 PolarHBondContact O-N 3.1Å; F408-G411 PolarHBondContact O-N 2.88Å; F408-T412 HydrophobicContact CD1-CG2 4.18Å; F408-T412 HydrophobicContact CD2-CG2 4.23Å; F408-T412 HydrophobicContact CE1-CG2 3.77Å; F408-T412 HydrophobicContact CE2-CG2 3.8Å; F408-T412 HydrophobicContact CG-CG2 4.42Å; F408-T412 HydrophobicContact CZ-CG2 3.56Å; F408-T412 WeakPolarHBondContact O-CB 3.22Å; F408-T412 WeakPolarHBondContact O-CG2 3.15Å; F408-T412 PolarHBondContact O-N 3.25Å; F408-T412 PolarHBondContact O-OG1 3.17Å; F408-F431 AromaticContact CD2-CD1 3.71Å; F408-F431 HydrophobicContact CD2-CD1 3.71Å; F408-F431 HydrophobicContact CD2-CE1 4.42Å; F408-F431 HydrophobicContact CD2-CG 4.45Å; F408-F431 HydrophobicContact CE2-CB 4.29Å; F408-F431 AromaticContact CE2-CD1 3.48Å; F408-F431 HydrophobicContact CE2-CD1 3.48Å; F408-F431 VanDerWaalsContact CE2-CD1 3.48Å; F408-F431 HydrophobicContact CE2-CE1 4.05Å; F408-F431 HydrophobicContact CE2-CG 4.02Å; F408-M434 HydrophobicContact CB-CB 3.81Å; F408-M434 HydrophobicContact CB-CE 3.83Å; F408-M434 HydrophobicContact CB-CG 3.9Å; F408-M434 HydrophobicContact CB-SD 4.05Å; F408-M434 HydrophobicContact CD1-CE 3.67Å; F408-M434 HydrophobicContact CD1-CG 4.24Å; F408-M434 HydrophobicContact CD2-CB 3.52Å; F408-M434 HydrophobicContact CD2-CG 3.76Å; F408-M434 HydrophobicContact CE1-CE 4.45Å; F408-M434 HydrophobicContact CE2-CB 4.31Å; F408-M434 HydrophobicContact CE2-CG 4.36Å; F408-M434 HydrophobicContact CG-CB 3.79Å; F408-M434 HydrophobicContact CG-CE 3.84Å; F408-M434 HydrophobicContact CG-CG 3.68Å; F408-M434 HydrophobicContact CG-SD 4.32Å; F408-A511 HydrophobicContact CE1-CB 4.41Å; F408-A515 HydrophobicContact CD1-CB 3.59Å; F408-A515 HydrophobicContact CE1-CB 4.23Å
409	G	96.6	Very high	94.2	Very high	0 Å²	0	37.2 Å²	37.2	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-62.2	-43.8	179.9	0	0	0	0	0	112.2	Y405 L406 T412 G413 S512	Y405-G409 PolarHBondContact O-N 3.05Å; L406-G409 PolarHBondContact O-N 3.47Å; G409-T412 PolarHBondContact O-OG1 3.25Å; G409-G413 PolarHBondContact O-N 3.39Å; G409-S512 WeakPolarHBondContact O-CB 3.35Å; G409-S512 PolarHBondContact O-OG 3.37Å
410	L	96.3	Very high	94.2	Very high	101 Å²	101	40.1 Å²	40.1	53%	0.529	21%	0.21	S	C	.	.	H	α-helix	trans	-67.9	-42.3	175	-66.7	177.8	0	0	0	112	L406 G413 F414	L406-L410 HydrophobicContact CD1-CD1 3.99Å; L406-L410 HydrophobicContact CD1-CG 4.19Å; L406-L410 HydrophobicContact CG-CD1 3.99Å; L406-L410 HydrophobicContact CG-CG 4.49Å; L406-L410 WeakPolarHBondContact O-CB 3.19Å; L406-L410 VanDerWaalsContact O-CG 3.28Å; L406-L410 WeakPolarHBondContact O-CG 3.2Å; L406-L410 PolarHBondContact O-N 2.68Å; L410-G413 PolarHBondContact O-N 3.42Å; L410-F414 WeakPolarHBondContact O-CB 3.43Å; L410-F414 PolarHBondContact O-N 2.98Å
411	G	94.9	Very high	94.1	Very high	2 Å²	2	41.7 Å²	41.7	2%	0.021	22%	0.22	C	C	.	.	H	α-helix	trans	-63.4	-52.2	-179.9	0	0	0	0	0	112.8	L407 F408 G413 F414 I415	L407-G411 PolarHBondContact O-N 3Å; F408-G411 PolarHBondContact O-N 2.88Å; G411-G413 VanDerWaalsContact C-N 3.35Å; G411-F414 PolarHBondContact O-N 2.69Å; G411-I415 VanDerWaalsContact O-CG1 3.32Å; G411-I415 WeakPolarHBondContact O-CG1 3.17Å; G411-I415 PolarHBondContact O-N 3.41Å
412	T	93.6	Very high	94	Very high	0 Å²	0	50.4 Å²	50.4	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-61	-43.3	174.3	49.4	0	0	0	0	111.4	N334 F408 G409 F414 I415 G416 F431 V508 S512	N334-T412 HydrophobicContact CB-CG2 4.41Å; F408-T412 HydrophobicContact CD1-CG2 4.18Å; F408-T412 HydrophobicContact CD2-CG2 4.23Å; F408-T412 HydrophobicContact CE1-CG2 3.77Å; F408-T412 HydrophobicContact CE2-CG2 3.8Å; F408-T412 HydrophobicContact CG-CG2 4.42Å; F408-T412 HydrophobicContact CZ-CG2 3.56Å; F408-T412 WeakPolarHBondContact O-CB 3.22Å; F408-T412 WeakPolarHBondContact O-CG2 3.15Å; F408-T412 PolarHBondContact O-N 3.25Å; F408-T412 PolarHBondContact O-OG1 3.17Å; G409-T412 PolarHBondContact O-OG1 3.25Å; T412-F414 VanDerWaalsContact C-N 3.33Å; T412-F414 PolarHBondContact O-N 2.97Å; T412-I415 PolarHBondContact O-N 3.21Å; T412-G416 PolarHBondContact O-N 3.34Å; T412-F431 HydrophobicContact CG2-CD1 4.2Å; T412-F431 HydrophobicContact CG2-CE1 3.41Å; T412-F431 VanDerWaalsContact CG2-CE1 3.41Å; T412-F431 HydrophobicContact CG2-CZ 4.02Å; T412-V508 WeakPolarHBondContact O-CG1 3.5Å; T412-S512 VanDerWaalsContact OG1-CA 3.25Å; T412-S512 WeakPolarHBondContact OG1-CA 3.04Å; T412-S512 WeakPolarHBondContact OG1-CB 3.2Å
413	G	93.9	Very high	93.8	Very high	14 Å²	14	48.3 Å²	48.3	14%	0.144	25%	0.248	C	C	.	.	H	α-helix	trans	-58.2	-43.9	176.7	0	0	0	0	0	112.5	G409 L410 G411 G416 L417 S512	G409-G413 PolarHBondContact O-N 3.39Å; L410-G413 PolarHBondContact O-N 3.42Å; G411-G413 VanDerWaalsContact C-N 3.35Å; G413-G416 PolarHBondContact O-N 3.41Å; G413-L417 VanDerWaalsContact O-CG 3.32Å; G413-L417 WeakPolarHBondContact O-CG 3.4Å; G413-L417 PolarHBondContact O-N 2.79Å; G413-S512 WeakPolarHBondContact CA-OG 3.43Å; G413-S512 PolarHBondContact N-OG 2.7Å
414	F	94.5	Very high	93.7	Very high	99 Å²	99	46.3 Å²	46.3	43%	0.434	24%	0.236	S	C	.	.	H	α-helix	trans	-66.9	-39.6	177.6	-164.7	-86.9	0	0	0	112.6	L410 G411 T412 G416 L417 F418 S423 L427	L410-F414 WeakPolarHBondContact O-CB 3.43Å; L410-F414 PolarHBondContact O-N 2.98Å; G411-F414 PolarHBondContact O-N 2.69Å; T412-F414 VanDerWaalsContact C-N 3.33Å; T412-F414 PolarHBondContact O-N 2.97Å; F414-G416 VanDerWaalsContact C-N 3.32Å; F414-G416 PolarHBondContact O-N 3.08Å; F414-L417 PolarHBondContact O-N 2.94Å; F414-F418 HydrophobicContact CD1-CB 4.47Å; F414-F418 HydrophobicContact CD1-CD2 4.15Å; F414-F418 AromaticContact CD2-CD2 3.78Å; F414-F418 HydrophobicContact CD2-CD2 3.78Å; F414-F418 HydrophobicContact CD2-CE2 4.05Å; F414-F418 HydrophobicContact CE1-CB 4.18Å; F414-F418 AromaticContact CE1-CD2 3.96Å; F414-F418 HydrophobicContact CE1-CD2 3.96Å; F414-F418 HydrophobicContact CE1-CG 4.43Å; F414-F418 AromaticContact CE2-CD2 3.55Å; F414-F418 HydrophobicContact CE2-CD2 3.55Å; F414-F418 AromaticContact CE2-CE2 3.74Å; F414-F418 HydrophobicContact CE2-CE2 3.74Å; F414-F418 HydrophobicContact CG-CD2 4.09Å; F414-F418 AromaticContact CZ-CD2 3.66Å; F414-F418 HydrophobicContact CZ-CD2 3.66Å; F414-F418 HydrophobicContact CZ-CE2 4.22Å; F414-F418 HydrophobicContact CZ-CG 4.32Å; F414-F418 PolarHBondContact O-N 3.28Å; F414-S423 WeakPolarHBondContact CE1-OG 3.3Å; F414-L427 HydrophobicContact CB-CD1 4.04Å; F414-L427 HydrophobicContact CD1-CD1 3.48Å; F414-L427 VanDerWaalsContact CD1-CD1 3.48Å; F414-L427 HydrophobicContact CE1-CD1 4.36Å; F414-L427 HydrophobicContact CG-CD1 4.14Å
415	I	93.1	Very high	93.6	Very high	0 Å²	0	48 Å²	48	0%	0	25%	0.245	C	C	.	.	H	α-helix	trans	-59.2	-44.7	173.3	-69.2	168	0	0	0	110.7	F341 G411 T412 F418 T424 L427 F431 V508	F341-I415 HydrophobicContact CD1-CG2 4.38Å; F341-I415 HydrophobicContact CE1-CG2 3.39Å; F341-I415 HydrophobicContact CZ-CG2 3.71Å; G411-I415 VanDerWaalsContact O-CG1 3.32Å; G411-I415 WeakPolarHBondContact O-CG1 3.17Å; G411-I415 PolarHBondContact O-N 3.41Å; T412-I415 PolarHBondContact O-N 3.21Å; I415-F418 CarbonylContact O-C 3.43Å; I415-T424 HydrophobicContact CD1-CG2 4.18Å; I415-T424 HydrophobicContact CG1-CG2 4.29Å; I415-T424 HydrophobicContact CG2-CG2 3.9Å; I415-L427 HydrophobicContact CD1-CB 3.65Å; I415-L427 HydrophobicContact CD1-CD1 4.44Å; I415-L427 HydrophobicContact CG1-CB 3.78Å; I415-L427 HydrophobicContact CG1-CD1 3.64Å; I415-L427 HydrophobicContact CG1-CG 4.37Å; I415-F431 HydrophobicContact CD1-CE1 3.79Å; I415-F431 HydrophobicContact CD1-CE2 4.33Å; I415-F431 HydrophobicContact CD1-CZ 3.37Å; I415-V508 HydrophobicContact CB-CG1 4.34Å; I415-V508 HydrophobicContact CG2-CG1 4.26Å
416	G	91	Very high	93.5	Very high	11 Å²	11	52.9 Å²	52.9	11%	0.113	28%	0.275	C	S	.	.	H	α-helix	trans	-65.8	-37.1	179.4	0	0	0	0	0	113.4	T412 G413 F414	T412-G416 PolarHBondContact O-N 3.34Å; G413-G416 PolarHBondContact O-N 3.41Å; F414-G416 VanDerWaalsContact C-N 3.32Å; F414-G416 PolarHBondContact O-N 3.08Å
417	L	91.2	Very high	93.3	Very high	127 Å²	127	51.4 Å²	51.4	67%	0.665	27%	0.267	S	S	*	.	H	α-helix	trans	-79.3	-35.4	180	-69.4	172	0	0	0	113.3	G413 F414	G413-L417 VanDerWaalsContact O-CG 3.32Å; G413-L417 WeakPolarHBondContact O-CG 3.4Å; G413-L417 PolarHBondContact O-N 2.79Å; F414-L417 PolarHBondContact O-N 2.94Å
418	F	91.7	Very high	93.2	Very high	118 Å²	118	48.6 Å²	48.6	52%	0.518	25%	0.252	S	S	.	.	S	Bend	trans	-129.3	70.1	-175.6	-54.6	-73.4	0	0	0	111	F414 I415 N420	F414-F418 HydrophobicContact CD1-CB 4.47Å; F414-F418 HydrophobicContact CD1-CD2 4.15Å; F414-F418 AromaticContact CD2-CD2 3.78Å; F414-F418 HydrophobicContact CD2-CD2 3.78Å; F414-F418 HydrophobicContact CD2-CE2 4.05Å; F414-F418 HydrophobicContact CE1-CB 4.18Å; F414-F418 AromaticContact CE1-CD2 3.96Å; F414-F418 HydrophobicContact CE1-CD2 3.96Å; F414-F418 HydrophobicContact CE1-CG 4.43Å; F414-F418 AromaticContact CE2-CD2 3.55Å; F414-F418 HydrophobicContact CE2-CD2 3.55Å; F414-F418 AromaticContact CE2-CE2 3.74Å; F414-F418 HydrophobicContact CE2-CE2 3.74Å; F414-F418 HydrophobicContact CG-CD2 4.09Å; F414-F418 AromaticContact CZ-CD2 3.66Å; F414-F418 HydrophobicContact CZ-CD2 3.66Å; F414-F418 HydrophobicContact CZ-CE2 4.22Å; F414-F418 HydrophobicContact CZ-CG 4.32Å; F414-F418 PolarHBondContact O-N 3.28Å; I415-F418 CarbonylContact O-C 3.43Å; F418-N420 PolarHBondContact O-N 3.25Å
419	P	88.2	Confident	93.1	Very high	56 Å²	56	49.6 Å²	49.6	36%	0.364	26%	0.259	S	S	.	.			trans	-65.2	103.1	-179.5	25.9	-33.6	0	0	0	110.4	F341 I345 V346	F341-P419 HydrophobicContact CZ-CB 4.32Å; I345-P419 HydrophobicContact CG2-CB 3.76Å; I345-P419 HydrophobicContact CG2-CG 4.03Å; V346-P419 HydrophobicContact CG2-CB 4.17Å
420	N	92.1	Very high	93	Very high	80 Å²	80	51.3 Å²	51.3	43%	0.428	27%	0.268	S	S	.	.			trans	-141.5	137.7	177.3	179.9	-72.4	0	0	0	109	F418 Y422 S423 T424	F418-N420 PolarHBondContact O-N 3.25Å; N420-Y422 PolarHBondContact O-N 2.86Å; N420-Y422 PolarHBondContact OD1-N 3.23Å; N420-S423 PolarHBondContact O-N 3.45Å; N420-S423 PolarHBondContact OD1-N 2.89Å; N420-T424 VanDerWaalsContact O-CB 3.25Å; N420-T424 WeakPolarHBondContact O-CB 3.42Å; N420-T424 PolarHBondContact O-N 3.33Å; N420-T424 PolarHBondContact O-OG1 3.17Å
421	V	91.8	Very high	92.9	Very high	34 Å²	34	46.5 Å²	46.5	21%	0.206	24%	0.243	C	C	.	.	H	α-helix	trans	-52.7	-53.7	-175.9	-171.3	0	0	0	0	111.7	V346 Y347 V369 T424 L425	V346-V421 HydrophobicContact CG1-CB 4.24Å; V346-V421 HydrophobicContact CG1-CG2 3.7Å; Y347-V421 HydrophobicContact CD2-CG2 4.4Å; Y347-V421 HydrophobicContact CE2-CG1 4.01Å; Y347-V421 HydrophobicContact CE2-CG2 3.76Å; V369-V421 HydrophobicContact CG1-CG1 3.98Å; V421-T424 PolarHBondContact O-N 3.44Å; V421-L425 HydrophobicContact CG1-CD1 4.07Å; V421-L425 WeakPolarHBondContact O-CG 3.33Å; V421-L425 PolarHBondContact O-N 3.38Å
422	Y	92.3	Very high	92.8	Very high	184 Å²	184	46.4 Å²	46.4	72%	0.722	24%	0.242	S	C	*	.	H	α-helix	trans	-68.6	-43.6	-174	-59.7	-71.9	0	0	0	111.7	N420 T424 L425 V426	N420-Y422 PolarHBondContact O-N 2.86Å; N420-Y422 PolarHBondContact OD1-N 3.23Å; Y422-T424 VanDerWaalsContact C-N 3.33Å; Y422-T424 PolarHBondContact O-N 2.97Å; Y422-L425 PolarHBondContact O-N 3.36Å; Y422-V426 VanDerWaalsContact O-CG2 3.32Å; Y422-V426 WeakPolarHBondContact O-CG2 3.47Å; Y422-V426 PolarHBondContact O-N 3.36Å
423	S	91.9	Very high	92.9	Very high	28 Å²	28	47 Å²	47	20%	0.196	25%	0.245	C	C	.	.	H	α-helix	trans	-59.1	-46.6	175.2	-176.7	0	0	0	0	111	F414 N420 V426 L427	F414-S423 WeakPolarHBondContact CE1-OG 3.3Å; N420-S423 PolarHBondContact O-N 3.45Å; N420-S423 PolarHBondContact OD1-N 2.89Å; S423-V426 PolarHBondContact O-N 2.94Å; S423-L427 WeakPolarHBondContact O-CB 3.34Å; S423-L427 WeakPolarHBondContact O-CD1 2.93Å; S423-L427 WeakPolarHBondContact O-CG 3.47Å; S423-L427 PolarHBondContact O-N 3.41Å
424	T	92.9	Very high	93	Very high	0 Å²	0	46.3 Å²	46.3	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-63.6	-46.1	-178.2	-54.1	0	0	0	0	111.4	F338 M342 I415 N420 V421 Y422 V426 L427 C428	F338-T424 HydrophobicContact CE2-CG2 3.71Å; F338-T424 HydrophobicContact CZ-CG2 3.75Å; M342-T424 HydrophobicContact CE-CG2 3.67Å; M342-T424 HydrophobicContact SD-CG2 4.33Å; I415-T424 HydrophobicContact CD1-CG2 4.18Å; I415-T424 HydrophobicContact CG1-CG2 4.29Å; I415-T424 HydrophobicContact CG2-CG2 3.9Å; N420-T424 VanDerWaalsContact O-CB 3.25Å; N420-T424 WeakPolarHBondContact O-CB 3.42Å; N420-T424 PolarHBondContact O-N 3.33Å; N420-T424 PolarHBondContact O-OG1 3.17Å; V421-T424 PolarHBondContact O-N 3.44Å; Y422-T424 VanDerWaalsContact C-N 3.33Å; Y422-T424 PolarHBondContact O-N 2.97Å; T424-V426 PolarHBondContact O-N 2.93Å; T424-L427 PolarHBondContact O-N 3.36Å; T424-C428 PolarHBondContact O-N 3.36Å; T424-C428 PolarHBondContact O-SG 3.27Å
425	L	93.1	Very high	92.9	Very high	37 Å²	37	42.1 Å²	42.1	19%	0.194	22%	0.221	C	C	.	.	H	α-helix	trans	-62.6	-40.8	177.7	-71.7	176.3	0	0	0	112.5	M342 V369 I376 V421 Y422 C428	M342-L425 HydrophobicContact CE-CD2 4.11Å; M342-L425 HydrophobicContact CE-CG 4.48Å; V369-L425 HydrophobicContact CG1-CD1 4.08Å; V369-L425 HydrophobicContact CG1-CD2 4.09Å; V369-L425 HydrophobicContact CG1-CG 4.39Å; I376-L425 HydrophobicContact CD1-CB 4.32Å; I376-L425 HydrophobicContact CD1-CD2 4.25Å; V421-L425 HydrophobicContact CG1-CD1 4.07Å; V421-L425 WeakPolarHBondContact O-CG 3.33Å; V421-L425 PolarHBondContact O-N 3.38Å; Y422-L425 PolarHBondContact O-N 3.36Å; L425-C428 WeakPolarHBondContact O-CB 3.25Å; L425-C428 PolarHBondContact O-N 3.39Å
426	V	93.8	Very high	92.9	Very high	102 Å²	102	42.1 Å²	42.1	62%	0.618	22%	0.221	S	C	*	.	H	α-helix	trans	-65	-43.9	175.3	171.8	0	0	0	0	110.5	Y422 S423 T424 C428 S429	Y422-V426 VanDerWaalsContact O-CG2 3.32Å; Y422-V426 WeakPolarHBondContact O-CG2 3.47Å; Y422-V426 PolarHBondContact O-N 3.36Å; S423-V426 PolarHBondContact O-N 2.94Å; T424-V426 PolarHBondContact O-N 2.93Å; V426-C428 VanDerWaalsContact C-N 3.25Å; V426-C428 PolarHBondContact O-N 3.2Å; V426-S429 VanDerWaalsContact O-CB 3.28Å; V426-S429 WeakPolarHBondContact O-CB 3.31Å; V426-S429 PolarHBondContact O-N 3.5Å; V426-S429 VanDerWaalsContact O-N 3.12Å; V426-S429 PolarHBondContact O-OG 2.92Å
427	L	94.4	Very high	93	Very high	28 Å²	28	41.6 Å²	41.6	15%	0.147	22%	0.216	C	C	.	.	H	α-helix	trans	-71.9	-16.8	-178.3	-68.9	168.6	0	0	0	113.5	F414 I415 S423 T424 S429 L430	F414-L427 HydrophobicContact CB-CD1 4.04Å; F414-L427 HydrophobicContact CD1-CD1 3.48Å; F414-L427 VanDerWaalsContact CD1-CD1 3.48Å; F414-L427 HydrophobicContact CE1-CD1 4.36Å; F414-L427 HydrophobicContact CG-CD1 4.14Å; I415-L427 HydrophobicContact CD1-CB 3.65Å; I415-L427 HydrophobicContact CD1-CD1 4.44Å; I415-L427 HydrophobicContact CG1-CB 3.78Å; I415-L427 HydrophobicContact CG1-CD1 3.64Å; I415-L427 HydrophobicContact CG1-CG 4.37Å; S423-L427 WeakPolarHBondContact O-CB 3.34Å; S423-L427 WeakPolarHBondContact O-CD1 2.93Å; S423-L427 WeakPolarHBondContact O-CG 3.47Å; S423-L427 PolarHBondContact O-N 3.41Å; T424-L427 PolarHBondContact O-N 3.36Å; L427-S429 PolarHBondContact O-N 3.19Å; L427-S429 VanDerWaalsContact O-N 3.17Å; L427-L430 HydrophobicContact CD2-CD1 3.57Å; L427-L430 HydrophobicContact CD2-CG 4.42Å; L427-L430 WeakPolarHBondContact O-CB 3.37Å; L427-L430 PolarHBondContact O-N 2.85Å
428	C	93.2	Very high	93.1	Very high	0 Å²	0	35.5 Å²	35.5	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-58.2	-24.3	167.9	-69.2	0	0	0	0	112.6	F338 G373 I376 N377 T424 L425 V426 L430 F431 G432	F338-C428 WeakPolarHBondContact CZ-SG 3.46Å; G373-C428 WeakPolarHBondContact O-CB 3.37Å; I376-C428 HydrophobicContact CB-CB 4.43Å; I376-C428 HydrophobicContact CG2-CB 4.24Å; N377-C428 WeakPolarHBondContact CA-O 3.45Å; T424-C428 PolarHBondContact O-N 3.36Å; T424-C428 PolarHBondContact O-SG 3.27Å; L425-C428 WeakPolarHBondContact O-CB 3.25Å; L425-C428 PolarHBondContact O-N 3.39Å; V426-C428 VanDerWaalsContact C-N 3.25Å; V426-C428 PolarHBondContact O-N 3.2Å; C428-L430 PolarHBondContact O-N 3.11Å; C428-F431 HydrophobicContact CB-CD2 4.3Å; C428-F431 VanDerWaalsContact O-CB 3.31Å; C428-F431 WeakPolarHBondContact O-CB 3.42Å; C428-F431 PolarHBondContact O-N 3.11Å; C428-F431 VanDerWaalsContact O-N 3.13Å; C428-G432 PolarHBondContact O-N 2.85Å
429	S	94.7	Very high	93	Very high	20 Å²	20	31 Å²	31	14%	0.14	16%	0.164	C	C	.	.	H	α-helix	trans	-59	-34.1	171.7	63.5	0	0	0	0	112.8	F380 V426 L427 F431 G432 V433	F380-S429 VanDerWaalsContact CD1-CB 3.5Å; V426-S429 VanDerWaalsContact O-CB 3.28Å; V426-S429 WeakPolarHBondContact O-CB 3.31Å; V426-S429 PolarHBondContact O-N 3.5Å; V426-S429 VanDerWaalsContact O-N 3.12Å; V426-S429 PolarHBondContact O-OG 2.92Å; L427-S429 PolarHBondContact O-N 3.19Å; L427-S429 VanDerWaalsContact O-N 3.17Å; S429-F431 VanDerWaalsContact C-N 3.29Å; S429-F431 PolarHBondContact O-N 2.69Å; S429-G432 PolarHBondContact O-N 3.33Å; S429-G432 VanDerWaalsContact O-N 3.11Å; S429-V433 PolarHBondContact O-N 3.44Å
430	L	95	Very high	93.1	Very high	36 Å²	36	28.3 Å²	28.3	19%	0.188	15%	0.147	C	C	.	.	H	α-helix	trans	-72.4	-25.2	178.4	-56.2	-179.8	0	0	0	112.1	L407 L427 C428 G432 V433 M434	L407-L430 HydrophobicContact CB-CD2 4.35Å; L427-L430 HydrophobicContact CD2-CD1 3.57Å; L427-L430 HydrophobicContact CD2-CG 4.42Å; L427-L430 WeakPolarHBondContact O-CB 3.37Å; L427-L430 PolarHBondContact O-N 2.85Å; C428-L430 PolarHBondContact O-N 3.11Å; L430-G432 PolarHBondContact O-N 2.87Å; L430-V433 WeakPolarHBondContact O-CB 3.28Å; L430-V433 PolarHBondContact O-N 3.43Å; L430-M434 PolarHBondContact O-N 3.37Å
431	F	94.1	Very high	93.2	Very high	0 Å²	0	24.5 Å²	24.5	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-64.6	-37.6	170.2	-56	-9.8	0	0	0	110.2	F331 N334 M335 F338 N377 F408 T412 I415 C428 S429 V433 M434 S435	F331-F431 HydrophobicContact CE2-CB 4.38Å; F331-F431 WeakPolarHBondContact CE2-O 3.17Å; N334-F431 WeakPolarHBondContact ND2-CE2 3.4Å; N334-F431 WeakPolarHBondContact ND2-CZ 3.48Å; M335-F431 HydrophobicContact CE-CB 3.51Å; M335-F431 HydrophobicContact CE-CD2 3.3Å; M335-F431 HydrophobicContact CE-CE2 4.18Å; M335-F431 HydrophobicContact CE-CG 3.65Å; F338-F431 AromaticContact CD2-CE2 3.81Å; F338-F431 HydrophobicContact CD2-CE2 3.81Å; F338-F431 HydrophobicContact CD2-CZ 4.39Å; F338-F431 AromaticContact CE2-CE2 3.7Å; F338-F431 HydrophobicContact CE2-CE2 3.7Å; F338-F431 HydrophobicContact CE2-CZ 4.23Å; F338-F431 HydrophobicContact CG-CE2 4.44Å; F338-F431 HydrophobicContact CZ-CE2 4.24Å; N377-F431 HydrophobicContact CB-CB 4.1Å; N377-F431 WeakPolarHBondContact OD1-CB 3.37Å; N377-F431 PolarHBondContact OD1-O 2.98Å; F408-F431 AromaticContact CD2-CD1 3.71Å; F408-F431 HydrophobicContact CD2-CD1 3.71Å; F408-F431 HydrophobicContact CD2-CE1 4.42Å; F408-F431 HydrophobicContact CD2-CG 4.45Å; F408-F431 HydrophobicContact CE2-CB 4.29Å; F408-F431 AromaticContact CE2-CD1 3.48Å; F408-F431 HydrophobicContact CE2-CD1 3.48Å; F408-F431 VanDerWaalsContact CE2-CD1 3.48Å; F408-F431 HydrophobicContact CE2-CE1 4.05Å; F408-F431 HydrophobicContact CE2-CG 4.02Å; T412-F431 HydrophobicContact CG2-CD1 4.2Å; T412-F431 HydrophobicContact CG2-CE1 3.41Å; T412-F431 VanDerWaalsContact CG2-CE1 3.41Å; T412-F431 HydrophobicContact CG2-CZ 4.02Å; I415-F431 HydrophobicContact CD1-CE1 3.79Å; I415-F431 HydrophobicContact CD1-CE2 4.33Å; I415-F431 HydrophobicContact CD1-CZ 3.37Å; C428-F431 HydrophobicContact CB-CD2 4.3Å; C428-F431 VanDerWaalsContact O-CB 3.31Å; C428-F431 WeakPolarHBondContact O-CB 3.42Å; C428-F431 PolarHBondContact O-N 3.11Å; C428-F431 VanDerWaalsContact O-N 3.13Å; S429-F431 VanDerWaalsContact C-N 3.29Å; S429-F431 PolarHBondContact O-N 2.69Å; F431-V433 VanDerWaalsContact C-N 3.3Å; F431-V433 PolarHBondContact O-N 2.94Å; F431-M434 WeakPolarHBondContact O-CB 3.42Å; F431-M434 PolarHBondContact O-N 3.33Å; F431-S435 WeakPolarHBondContact O-CB 3.46Å; F431-S435 PolarHBondContact O-N 3.34Å
432	G	93.3	Very high	93.2	Very high	0 Å²	0	22.9 Å²	22.9	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-62.8	-39.7	177.5	0	0	0	0	0	111.9	N377 S381 C428 S429 L430 S435 S436	N377-G432 VanDerWaalsContact O-CA 3.22Å; N377-G432 WeakPolarHBondContact O-CA 3.3Å; N377-G432 WeakPolarHBondContact OD1-CA 3.35Å; N377-G432 PolarHBondContact OD1-N 3.44Å; S381-G432 VanDerWaalsContact CA-O 3.31Å; S381-G432 WeakPolarHBondContact CA-O 3.39Å; S381-G432 WeakPolarHBondContact CB-O 3.32Å; C428-G432 PolarHBondContact O-N 2.85Å; S429-G432 PolarHBondContact O-N 3.33Å; S429-G432 VanDerWaalsContact O-N 3.11Å; L430-G432 PolarHBondContact O-N 2.87Å; G432-S435 PolarHBondContact O-N 3.39Å; G432-S436 WeakPolarHBondContact O-CB 3.35Å; G432-S436 PolarHBondContact O-N 2.95Å
433	V	94.6	Very high	93	Very high	13 Å²	13	14.3 Å²	14.3	8%	0.079	8%	0.083	C	C	.	.	H	α-helix	trans	-59.5	-46.7	174.2	176.3	0	0	0	0	111.1	Y384 L407 S429 L430 F431 T437	Y384-V433 HydrophobicContact CD1-CB 4.45Å; Y384-V433 HydrophobicContact CD1-CG1 4.21Å; Y384-V433 HydrophobicContact CD2-CG1 4.47Å; Y384-V433 HydrophobicContact CD2-CG2 4.07Å; Y384-V433 HydrophobicContact CE1-CB 4.45Å; Y384-V433 HydrophobicContact CE1-CG1 3.74Å; Y384-V433 HydrophobicContact CE2-CG1 4.04Å; Y384-V433 HydrophobicContact CE2-CG2 4.3Å; Y384-V433 HydrophobicContact CG-CG2 4.21Å; L407-V433 HydrophobicContact CD1-CG1 4.03Å; S429-V433 PolarHBondContact O-N 3.44Å; L430-V433 WeakPolarHBondContact O-CB 3.28Å; L430-V433 PolarHBondContact O-N 3.43Å; F431-V433 VanDerWaalsContact C-N 3.3Å; F431-V433 PolarHBondContact O-N 2.94Å; V433-T437 VanDerWaalsContact O-CB 3.32Å; V433-T437 WeakPolarHBondContact O-CB 3.25Å; V433-T437 PolarHBondContact O-N 2.9Å; V433-T437 PolarHBondContact O-OG1 2.97Å
434	M	95.3	Very high	92.8	Very high	0 Å²	0	13 Å²	13	0%	0	7%	0.074	C	C	.	.	H	α-helix	trans	-62.3	-51.2	177.1	-171.9	56.2	134.4	0	0	112.2	F331 Y405 F408 L430 F431 S436 T437 L438 A515	F331-M434 HydrophobicContact CB-CG 4.34Å; F331-M434 HydrophobicContact CD2-CB 4.08Å; F331-M434 HydrophobicContact CD2-CG 3.84Å; F331-M434 HydrophobicContact CE2-CB 4.47Å; F331-M434 HydrophobicContact CG-CG 4.42Å; Y405-M434 HydrophobicContact CD1-CE 3.56Å; Y405-M434 HydrophobicContact CE1-CE 3.84Å; Y405-M434 HydrophobicContact CG-CE 4.07Å; F408-M434 HydrophobicContact CB-CB 3.81Å; F408-M434 HydrophobicContact CB-CE 3.83Å; F408-M434 HydrophobicContact CB-CG 3.9Å; F408-M434 HydrophobicContact CB-SD 4.05Å; F408-M434 HydrophobicContact CD1-CE 3.67Å; F408-M434 HydrophobicContact CD1-CG 4.24Å; F408-M434 HydrophobicContact CD2-CB 3.52Å; F408-M434 HydrophobicContact CD2-CG 3.76Å; F408-M434 HydrophobicContact CE1-CE 4.45Å; F408-M434 HydrophobicContact CE2-CB 4.31Å; F408-M434 HydrophobicContact CE2-CG 4.36Å; F408-M434 HydrophobicContact CG-CB 3.79Å; F408-M434 HydrophobicContact CG-CE 3.84Å; F408-M434 HydrophobicContact CG-CG 3.68Å; F408-M434 HydrophobicContact CG-SD 4.32Å; L430-M434 PolarHBondContact O-N 3.37Å; F431-M434 WeakPolarHBondContact O-CB 3.42Å; F431-M434 PolarHBondContact O-N 3.33Å; M434-S436 PolarHBondContact O-N 2.86Å; M434-T437 WeakPolarHBondContact O-CB 3.15Å; M434-T437 PolarHBondContact O-N 3.31Å; M434-T437 VanDerWaalsContact O-N 3.09Å; M434-L438 HydrophobicContact CG-CD1 3.99Å; M434-L438 HydrophobicContact CG-CG 4.43Å; M434-L438 WeakPolarHBondContact O-CG 3.47Å; M434-L438 PolarHBondContact O-N 3.42Å; M434-L438 HydrophobicContact SD-CD1 4.27Å; M434-L438 HydrophobicContact SD-CG 4.24Å; M434-A515 HydrophobicContact CE-CB 4.34Å
435	S	92.8	Very high	92.7	Very high	10 Å²	10	13 Å²	13	7%	0.07	7%	0.074	C	C	.	.	H	α-helix	trans	-52.7	-54.6	179.3	-177.8	0	0	0	0	111	F431 G432 T437 L438 Y439	F431-S435 WeakPolarHBondContact O-CB 3.46Å; F431-S435 PolarHBondContact O-N 3.34Å; G432-S435 PolarHBondContact O-N 3.39Å; S435-T437 VanDerWaalsContact C-N 3.3Å; S435-T437 PolarHBondContact O-N 3.14Å; S435-L438 PolarHBondContact O-N 2.67Å; S435-Y439 WeakPolarHBondContact O-CD2 3.43Å; S435-Y439 PolarHBondContact O-N 2.96Å
436	S	93.3	Very high	92.4	Very high	0 Å²	0	11.5 Å²	11.5	0%	0	7%	0.066	C	C	.	.	H	α-helix	trans	-60.9	-38.2	178.2	170.7	0	0	0	0	112.3	S381 Y384 S385 Q388 G432 M434 Y439 T440	S381-S436 WeakPolarHBondContact O-CB 3.42Å; S381-S436 WeakPolarHBondContact OG-CB 3.49Å; S381-S436 PolarHBondContact OG-N 3.46Å; Y384-S436 WeakPolarHBondContact CD1-OG 3.33Å; S385-S436 WeakPolarHBondContact CA-OG 3.47Å; S385-S436 PolarHBondContact N-OG 3.1Å; S385-S436 WeakPolarHBondContact OG-CB 3.49Å; S385-S436 PolarHBondContact OG-OG 3.42Å; Q388-S436 VanDerWaalsContact CD-OG 3.25Å; Q388-S436 PolarHBondContact NE2-O 3.43Å; Q388-S436 PolarHBondContact NE2-OG 2.86Å; Q388-S436 PolarHBondContact OE1-OG 2.71Å; G432-S436 WeakPolarHBondContact O-CB 3.35Å; G432-S436 PolarHBondContact O-N 2.95Å; M434-S436 PolarHBondContact O-N 2.86Å; S436-Y439 PolarHBondContact O-N 2.93Å; S436-T440 PolarHBondContact O-N 2.99Å; S436-T440 VanDerWaalsContact O-N 3.12Å; S436-T440 PolarHBondContact O-OG1 3.04Å
437	T	94.1	Very high	91.9	Very high	0 Å²	0	7.1 Å²	7.1	0%	0	4%	0.039	C	C	.	.	H	α-helix	trans	-65	-44	177.3	-57.9	0	0	0	0	111.8	Y401 V433 M434 S435 Y439 T440 V441 P442	Y401-T437 HydrophobicContact CD2-CG2 3.65Å; Y401-T437 HydrophobicContact CE2-CG2 4.33Å; V433-T437 VanDerWaalsContact O-CB 3.32Å; V433-T437 WeakPolarHBondContact O-CB 3.25Å; V433-T437 PolarHBondContact O-N 2.9Å; V433-T437 PolarHBondContact O-OG1 2.97Å; M434-T437 WeakPolarHBondContact O-CB 3.15Å; M434-T437 PolarHBondContact O-N 3.31Å; M434-T437 VanDerWaalsContact O-N 3.09Å; S435-T437 VanDerWaalsContact C-N 3.3Å; S435-T437 PolarHBondContact O-N 3.14Å; T437-Y439 VanDerWaalsContact C-N 3.32Å; T437-Y439 PolarHBondContact O-N 3.36Å; T437-T440 PolarHBondContact O-N 3.25Å; T437-V441 HydrophobicContact CG2-CB 4.24Å; T437-V441 HydrophobicContact CG2-CG2 3.78Å; T437-V441 WeakPolarHBondContact O-CB 3.38Å; T437-V441 PolarHBondContact O-N 3.05Å; T437-P442 VanDerWaalsContact O-CD 3.3Å; T437-P442 WeakPolarHBondContact O-CD 3.5Å
438	L	93.4	Very high	91.5	Very high	0 Å²	0	6.4 Å²	6.4	0%	0	4%	0.035	C	C	.	.	H	α-helix	trans	-66.1	-34.9	178.2	-68.6	172.7	0	0	0	112.1	H324 W328 F331 Y401 M434 S435	H324-L438 PolarHBondContact CE1-O 2.97Å; W328-L438 HydrophobicContact CD2-CD1 4.08Å; W328-L438 HydrophobicContact CE3-CD1 4.38Å; W328-L438 HydrophobicContact CG-CD1 4.36Å; W328-L438 HydrophobicContact CZ2-CB 3.94Å; F331-L438 HydrophobicContact CB-CD1 3.79Å; F331-L438 HydrophobicContact CG-CD1 4.14Å; Y401-L438 HydrophobicContact CE2-CD2 4.06Å; M434-L438 HydrophobicContact CG-CD1 3.99Å; M434-L438 HydrophobicContact CG-CG 4.43Å; M434-L438 WeakPolarHBondContact O-CG 3.47Å; M434-L438 PolarHBondContact O-N 3.42Å; M434-L438 HydrophobicContact SD-CD1 4.27Å; M434-L438 HydrophobicContact SD-CG 4.24Å; S435-L438 PolarHBondContact O-N 2.67Å
439	Y	89.7	Confident	91.2	Very high	23 Å²	23	6.4 Å²	6.4	9%	0.09	4%	0.035	C	C	.	.	H	α-helix	trans	-74.4	-27.3	177.5	-79.6	-58.9	0	0	0	114.3	T187 W328 S435 S436 T437 F443	T187-Y439 HydrophobicContact CG2-CE2 4.08Å; W328-Y439 HydrophobicContact CH2-CD1 4.36Å; W328-Y439 HydrophobicContact CH2-CD2 4.45Å; W328-Y439 AromaticContact CH2-CE1 3.77Å; W328-Y439 HydrophobicContact CH2-CE1 3.77Å; W328-Y439 AromaticContact CH2-CE2 3.89Å; W328-Y439 HydrophobicContact CH2-CE2 3.89Å; W328-Y439 AromaticContact CH2-CZ 3.53Å; W328-Y439 HydrophobicContact CZ2-CD1 4.15Å; W328-Y439 AromaticContact CZ2-CE1 3.89Å; W328-Y439 HydrophobicContact CZ2-CE1 3.89Å; S435-Y439 WeakPolarHBondContact O-CD2 3.43Å; S435-Y439 PolarHBondContact O-N 2.96Å; S436-Y439 PolarHBondContact O-N 2.93Å; T437-Y439 VanDerWaalsContact C-N 3.32Å; T437-Y439 PolarHBondContact O-N 3.36Å; Y439-F443 WeakPolarHBondContact O-CD2 3.32Å
440	T	90.5	Very high	90.6	Very high	0 Å²	0	6 Å²	6	0%	0	3%	0.031	C	C	.	.	H	α-helix	trans	-107.5	-54	-174.6	61.7	0	0	0	0	114.3	L180 A184 Q388 S436 T437 F443 N444	L180-T440 WeakPolarHBondContact CD2-O 3.49Å; L180-T440 HydrophobicContact CG-CG2 4.35Å; A184-T440 HydrophobicContact CB-CG2 3.38Å; Q388-T440 VanDerWaalsContact CD-OG1 3.25Å; Q388-T440 PolarHBondContact NE2-OG1 3.45Å; Q388-T440 VanDerWaalsContact OE1-CG2 3.25Å; Q388-T440 PolarHBondContact OE1-OG1 3.22Å; S436-T440 PolarHBondContact O-N 2.99Å; S436-T440 VanDerWaalsContact O-N 3.12Å; S436-T440 PolarHBondContact O-OG1 3.04Å; T437-T440 PolarHBondContact O-N 3.25Å; T440-F443 PolarHBondContact O-N 3.11Å; T440-N444 PolarHBondContact O-N 3.46Å
441	V	92.8	Very high	90	Very high	0 Å²	0	8.8 Å²	8.8	0%	0	4%	0.039	C	C	.	.	H	α-helix	trans	-65	-45.5	-163.5	-178.4	0	0	0	0	113.6	L397 L400 Y401 T437 F443 N444 L445	L397-V441 HydrophobicContact CB-CG1 4.38Å; L397-V441 HydrophobicContact CD2-CG1 4.42Å; L397-V441 WeakPolarHBondContact O-CG1 3.32Å; L400-V441 HydrophobicContact CB-CG2 4.29Å; L400-V441 HydrophobicContact CD2-CG2 3.51Å; L400-V441 HydrophobicContact CG-CG2 3.9Å; Y401-V441 HydrophobicContact CD1-CG1 4.47Å; Y401-V441 HydrophobicContact CG-CG1 4.08Å; T437-V441 HydrophobicContact CG2-CB 4.24Å; T437-V441 HydrophobicContact CG2-CG2 3.78Å; T437-V441 WeakPolarHBondContact O-CB 3.38Å; T437-V441 PolarHBondContact O-N 3.05Å; V441-F443 VanDerWaalsContact C-N 3.34Å; V441-F443 PolarHBondContact O-N 3.17Å; V441-N444 PolarHBondContact O-N 3.5Å; V441-L445 HydrophobicContact CG1-CD1 3.91Å; V441-L445 HydrophobicContact CG1-CG 4.26Å; V441-L445 WeakPolarHBondContact O-CG 3.34Å; V441-L445 PolarHBondContact O-N 3.36Å
442	P	92.2	Very high	89.5	Confident	0 Å²	0	10.5 Å²	10.5	0%	0	5%	0.047	C	C	.	.	H	α-helix	trans	-62.2	-38.3	179.9	-27.3	39.3	0	0	0	113.4	L320 H324 Y401 T437 L445 I446 L479	L320-P442 HydrophobicContact CD1-CB 4.24Å; H324-P442 VanDerWaalsContact ND1-CG 3.33Å; H324-P442 WeakPolarHBondContact ND1-CG 3.35Å; Y401-P442 HydrophobicContact CE1-CG 4.26Å; Y401-P442 HydrophobicContact CE2-CG 4.15Å; T437-P442 VanDerWaalsContact O-CD 3.3Å; T437-P442 WeakPolarHBondContact O-CD 3.5Å; P442-L445 PolarHBondContact O-N 3.46Å; P442-I446 WeakPolarHBondContact O-CG1 3.05Å; P442-I446 PolarHBondContact O-N 2.99Å; P442-L479 HydrophobicContact CB-CD1 4.29Å; P442-L479 HydrophobicContact CB-CD2 3.68Å
443	F	88.4	Confident	88.9	Confident	3 Å²	3	12.5 Å²	12.5	1%	0.013	6%	0.056	C	C	.	.	H	α-helix	trans	-75.2	-31.3	178.4	-60.4	-86.8	0	0	0	112.1	K164 F168 L180 Y439 T440 V441 T447 L479	K164-F443 HydrophobicContact CD-CD1 3.95Å; K164-F443 HydrophobicContact CD-CD2 4.5Å; K164-F443 HydrophobicContact CD-CE1 3.67Å; K164-F443 HydrophobicContact CD-CE2 4.26Å; K164-F443 HydrophobicContact CD-CG 4.37Å; K164-F443 HydrophobicContact CD-CZ 3.86Å; F168-F443 HydrophobicContact CZ-CB 4.19Å; L180-F443 HydrophobicContact CD1-CB 4.31Å; L180-F443 HydrophobicContact CD2-CB 3.6Å; Y439-F443 WeakPolarHBondContact O-CD2 3.32Å; T440-F443 PolarHBondContact O-N 3.11Å; V441-F443 VanDerWaalsContact C-N 3.34Å; V441-F443 PolarHBondContact O-N 3.17Å; F443-T447 PolarHBondContact O-N 2.93Å; F443-T447 VanDerWaalsContact O-N 3.12Å; F443-T447 PolarHBondContact O-OG1 3.25Å; F443-L479 HydrophobicContact CD1-CD2 3.67Å; F443-L479 HydrophobicContact CD2-CD2 4.12Å; F443-L479 HydrophobicContact CE1-CB 4.47Å; F443-L479 HydrophobicContact CE1-CD2 3.57Å; F443-L479 HydrophobicContact CE1-CG 4.33Å; F443-L479 HydrophobicContact CE2-CD2 4.01Å; F443-L479 HydrophobicContact CG-CD2 3.94Å; F443-L479 HydrophobicContact CZ-CD2 3.73Å; F443-L479 HydrophobicContact CZ-CG 4.33Å
444	N	88.4	Confident	88.1	Confident	2 Å²	2	15.8 Å²	15.8	1%	0.011	7%	0.071	C	C	.	.	H	α-helix	trans	-65.2	-43.7	169.2	-78.9	-8.5	0	0	0	111.4	L180 L397 T440 V441 I446 T447 E448	L180-N444 WeakPolarHBondContact CD2-OD1 3.29Å; L397-N444 HydrophobicContact CD1-CB 4.21Å; L397-N444 HydrophobicContact CD2-CB 3.85Å; T440-N444 PolarHBondContact O-N 3.46Å; V441-N444 PolarHBondContact O-N 3.5Å; N444-I446 PolarHBondContact O-N 3.49Å; N444-T447 WeakPolarHBondContact O-CB 3.42Å; N444-T447 PolarHBondContact O-N 3.29Å; N444-T447 VanDerWaalsContact O-N 3.07Å; N444-E448 PolarHBondContact O-N 2.88Å
445	L	90.5	Very high	87.4	Confident	0 Å²	0	19.5 Å²	19.5	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-60.7	-42.6	175.7	-76.2	168.9	0	0	0	112	L320 L397 Y401 V441 P442 T447 E448 Y449 V526 V529	L320-L445 HydrophobicContact CD1-CB 4.23Å; L320-L445 HydrophobicContact CD1-CD1 3.63Å; L320-L445 HydrophobicContact CD2-CB 3.9Å; L397-L445 HydrophobicContact CB-CD2 3.86Å; L397-L445 HydrophobicContact CB-CG 4.27Å; L397-L445 HydrophobicContact CD1-CD2 4.11Å; L397-L445 HydrophobicContact CD1-CG 4.46Å; Y401-L445 HydrophobicContact CD1-CD1 4.31Å; V441-L445 HydrophobicContact CG1-CD1 3.91Å; V441-L445 HydrophobicContact CG1-CG 4.26Å; V441-L445 WeakPolarHBondContact O-CG 3.34Å; V441-L445 PolarHBondContact O-N 3.36Å; P442-L445 PolarHBondContact O-N 3.46Å; L445-T447 VanDerWaalsContact C-N 3.26Å; L445-T447 PolarHBondContact O-N 3.42Å; L445-E448 PolarHBondContact O-N 3.38Å; L445-Y449 HydrophobicContact CB-CE2 4.35Å; L445-Y449 HydrophobicContact CD2-CE1 4.5Å; L445-Y449 WeakPolarHBondContact O-CB 3.39Å; L445-Y449 WeakPolarHBondContact O-CD2 3.38Å; L445-Y449 PolarHBondContact O-N 3.42Å; L445-V526 HydrophobicContact CD1-CG1 3.92Å; L445-V529 HydrophobicContact CD2-CG2 4.13Å
446	I	86.3	Confident	86.9	Confident	5 Å²	5	24.1 Å²	24.1	3%	0.026	11%	0.107	C	C	.	.	H	α-helix	trans	-57.3	-43.3	172.6	-73.2	176.6	0	0	0	110.8	Y317 L320 P442 N444 Y449 H450 D475 L479	Y317-I446 HydrophobicContact CD1-CG1 4.45Å; Y317-I446 HydrophobicContact CE1-CG2 4.48Å; L320-I446 HydrophobicContact CD2-CD1 4.36Å; L320-I446 HydrophobicContact CD2-CG1 3.58Å; P442-I446 WeakPolarHBondContact O-CG1 3.05Å; P442-I446 PolarHBondContact O-N 2.99Å; N444-I446 PolarHBondContact O-N 3.49Å; I446-Y449 PolarHBondContact O-N 2.91Å; I446-H450 PolarHBondContact O-CD2 2.88Å; I446-H450 PolarHBondContact O-N 3.27Å; I446-D475 HydrophobicContact CG2-CB 4.46Å; I446-L479 HydrophobicContact CD1-CB 3.93Å; I446-L479 HydrophobicContact CD1-CD1 4.47Å; I446-L479 HydrophobicContact CD1-CD2 3.47Å; I446-L479 VanDerWaalsContact CD1-CD2 3.47Å; I446-L479 HydrophobicContact CD1-CG 4.15Å
447	T	83	Confident	85.9	Confident	9 Å²	9	30.2 Å²	30.2	6%	0.055	13%	0.13	C	C	.	.	H	α-helix	trans	-62.7	-44.7	-178.3	-58.3	0	0	0	0	111.5	K176 F443 N444 L445 H450 R451	K176-T447 HydrophobicContact CB-CG2 4.47Å; K176-T447 HydrophobicContact CD-CG2 3.91Å; F443-T447 PolarHBondContact O-N 2.93Å; F443-T447 VanDerWaalsContact O-N 3.12Å; F443-T447 PolarHBondContact O-OG1 3.25Å; N444-T447 WeakPolarHBondContact O-CB 3.42Å; N444-T447 PolarHBondContact O-N 3.29Å; N444-T447 VanDerWaalsContact O-N 3.07Å; L445-T447 VanDerWaalsContact C-N 3.26Å; L445-T447 PolarHBondContact O-N 3.42Å; T447-H450 PolarHBondContact O-N 2.91Å; T447-R451 PolarHBondContact O-N 2.87Å; T447-R451 VanDerWaalsContact O-N 3.16Å
448	E	87	Confident	84.9	Confident	13 Å²	13	36.7 Å²	36.7	6%	0.061	16%	0.16	C	C	.	.	H	α-helix	trans	-76.5	-33.4	-179.9	-166.5	59.2	-135.8	0	0	112.4	H173 N444 L445 H450 R451 E452 V529	H173-E448 IonicContact CE1-OE2 3.15Å; H173-E448 PolarHBondContact CE1-OE2 3Å; H173-E448 IonicContact NE2-OE2 3.01Å; H173-E448 PolarHBondContact NE2-OE2 3.26Å; N444-E448 PolarHBondContact O-N 2.88Å; L445-E448 PolarHBondContact O-N 3.38Å; E448-H450 VanDerWaalsContact C-N 3.29Å; E448-H450 PolarHBondContact O-N 3.44Å; E448-R451 WeakPolarHBondContact O-CB 3.43Å; E448-R451 PolarHBondContact O-N 3.06Å; E448-R451 WeakPolarHBondContact OE1-CD 3.4Å; E448-R451 IonicContact OE1-CZ 3Å; E448-R451 IonicContact OE1-NE 2.66Å; E448-R451 IonicContact OE1-NH1 3.09Å; E448-R451 PolarHBondContact OE1-NH1 3.39Å; E448-R451 VanDerWaalsContact OE1-NH1 3.1Å; E448-R451 IonicContact OE2-CZ 3.17Å; E448-R451 IonicContact OE2-NH1 3.6Å; E448-R451 PolarHBondContact OE2-NH1 3.38Å; E448-E452 PolarHBondContact O-N 2.93Å; E448-V529 HydrophobicContact CB-CG1 3.83Å; E448-V529 HydrophobicContact CG-CB 4.44Å; E448-V529 HydrophobicContact CG-CG1 3.05Å
449	Y	87	Confident	83.9	Confident	1 Å²	1	44 Å²	44	0%	0.004	20%	0.195	C	C	.	.	H	α-helix	trans	-58.8	-41.1	170.2	-68	-19.1	0	0	0	112.1	H316 Y317 L320 L445 I446 R451 E453 R527 V529	H316-Y449 HydrophobicContact CB-CE2 4.39Å; H316-Y449 AromaticContact CD2-CD2 3.81Å; H316-Y449 AromaticContact CD2-CG 3.85Å; Y317-Y449 HydrophobicContact CD1-CD2 4.11Å; Y317-Y449 HydrophobicContact CE1-CD2 4.03Å; Y317-Y449 HydrophobicContact CE1-CG 4.45Å; Y317-Y449 HydrophobicContact CG-CD2 4.5Å; Y317-Y449 WeakPolarHBondContact OH-CB 3.09Å; L320-Y449 HydrophobicContact CB-CE2 4.45Å; L320-Y449 HydrophobicContact CD2-CD2 4.34Å; L320-Y449 HydrophobicContact CD2-CE2 3.95Å; L445-Y449 HydrophobicContact CB-CE2 4.35Å; L445-Y449 HydrophobicContact CD2-CE1 4.5Å; L445-Y449 WeakPolarHBondContact O-CB 3.39Å; L445-Y449 WeakPolarHBondContact O-CD2 3.38Å; L445-Y449 PolarHBondContact O-N 3.42Å; I446-Y449 PolarHBondContact O-N 2.91Å; Y449-R451 VanDerWaalsContact C-N 3.32Å; Y449-R451 PolarHBondContact O-N 3.01Å; Y449-E453 WeakPolarHBondContact O-CG 3.4Å; Y449-E453 PolarHBondContact O-N 3.46Å; Y449-E453 VanDerWaalsContact O-N 3.08Å; Y449-R527 HydrophobicContact CE1-CB 4.04Å; Y449-R527 PolarHBondContact OH-N 3.13Å; Y449-R527 PolarHBondContact OH-O 3.38Å; Y449-V529 HydrophobicContact CD1-CG2 3.92Å; Y449-V529 HydrophobicContact CE1-CG2 3.38Å
450	H	81.6	Confident	82.9	Confident	12 Å²	12	45.4 Å²	45.4	6%	0.056	21%	0.211	C	C	.	.	H	α-helix	trans	-64.7	-37.6	173.9	-77.8	-56.7	0	0	0	112.5	Y317 I446 T447 E448 E453 E454 D475	Y317-H450 PolarHBondContact OH-N 3.36Å; Y317-H450 PolarHBondContact OH-ND1 2.93Å; I446-H450 PolarHBondContact O-CD2 2.88Å; I446-H450 PolarHBondContact O-N 3.27Å; T447-H450 PolarHBondContact O-N 2.91Å; E448-H450 VanDerWaalsContact C-N 3.29Å; E448-H450 PolarHBondContact O-N 3.44Å; H450-E453 IonicContact ND1-OE2 3.7Å; H450-E453 PolarHBondContact O-N 3.01Å; H450-E454 WeakPolarHBondContact O-CB 3.49Å; H450-E454 VanDerWaalsContact O-CG 3.28Å; H450-E454 WeakPolarHBondContact O-CG 3.09Å; H450-E454 PolarHBondContact O-N 3.38Å; H450-D475 IonicContact CE1-OD2 2.65Å; H450-D475 PolarHBondContact CE1-OD2 3.49Å; H450-D475 IonicContact NE2-OD2 2.68Å; H450-D475 PolarHBondContact NE2-OD2 3.28Å
451	R	81.9	Confident	81.3	Confident	94 Å²	94	51.9 Å²	51.9	36%	0.355	25%	0.253	S	S	.	.	H	α-helix	trans	-67.3	-42.2	178.7	175.7	171.7	171.4	-136.9	1.8	112	H173 T447 E448 Y449 E454 K455	H173-R451 WeakPolarHBondContact NE2-CD 3.43Å; T447-R451 PolarHBondContact O-N 2.87Å; T447-R451 VanDerWaalsContact O-N 3.16Å; E448-R451 WeakPolarHBondContact O-CB 3.43Å; E448-R451 PolarHBondContact O-N 3.06Å; E448-R451 WeakPolarHBondContact OE1-CD 3.4Å; E448-R451 IonicContact OE1-CZ 3Å; E448-R451 IonicContact OE1-NE 2.66Å; E448-R451 IonicContact OE1-NH1 3.09Å; E448-R451 PolarHBondContact OE1-NH1 3.39Å; E448-R451 VanDerWaalsContact OE1-NH1 3.1Å; E448-R451 IonicContact OE2-CZ 3.17Å; E448-R451 IonicContact OE2-NH1 3.6Å; E448-R451 PolarHBondContact OE2-NH1 3.38Å; Y449-R451 VanDerWaalsContact C-N 3.32Å; Y449-R451 PolarHBondContact O-N 3.01Å; R451-E454 PolarHBondContact O-N 2.88Å; R451-K455 HydrophobicContact CG-CD 4.3Å; R451-K455 VanDerWaalsContact CZ-NZ 3.32Å; R451-K455 VanDerWaalsContact O-CG 3.3Å; R451-K455 WeakPolarHBondContact O-CG 3.31Å; R451-K455 PolarHBondContact O-N 2.79Å
452	E	83.5	Confident	79.7	Confident	36 Å²	36	56 Å²	56	17%	0.168	30%	0.295	C	S	.	.	H	α-helix	trans	-59.4	-48.2	172.8	-71.6	-174.9	165.2	0	0	110.8	E448 E454 K455 E456 R527	E448-E452 PolarHBondContact O-N 2.93Å; E452-E454 VanDerWaalsContact C-N 3.33Å; E452-E454 PolarHBondContact O-N 2.95Å; E452-K455 PolarHBondContact O-N 3.4Å; E452-E456 WeakPolarHBondContact O-CB 3.44Å; E452-E456 WeakPolarHBondContact O-CG 3.47Å; E452-E456 PolarHBondContact O-N 3.13Å; E452-R527 IonicContact OE2-CZ 2.93Å; E452-R527 VanDerWaalsContact OE2-CZ 3.27Å; E452-R527 IonicContact OE2-NE 3.16Å; E452-R527 IonicContact OE2-NH1 2.66Å; E452-R527 PolarHBondContact OE2-NH1 3.35Å; E452-R527 IonicContact OE2-NH2 3.41Å; E452-R527 PolarHBondContact OE2-NH2 2.94Å
453	E	81	Confident	77.6	Confident	42 Å²	42	58.5 Å²	58.5	20%	0.196	32%	0.321	C	S	.	.	H	α-helix	trans	-62.6	-37.1	178.1	-72.9	179	159.1	0	0	112.8	H316 Y317 Y449 H450 R457	H316-E453 IonicContact CE1-OE1 3.6Å; H316-E453 PolarHBondContact CE1-OE1 3.5Å; H316-E453 IonicContact NE2-OE1 3.73Å; H316-E453 PolarHBondContact NE2-OE1 3.41Å; H316-E453 VanDerWaalsContact NE2-OE1 3.16Å; Y317-E453 VanDerWaalsContact CE2-OE1 3.29Å; Y317-E453 WeakPolarHBondContact CE2-OE1 3.42Å; Y317-E453 PolarHBondContact OH-OE2 2.82Å; Y449-E453 WeakPolarHBondContact O-CG 3.4Å; Y449-E453 PolarHBondContact O-N 3.46Å; Y449-E453 VanDerWaalsContact O-N 3.08Å; H450-E453 IonicContact ND1-OE2 3.7Å; H450-E453 PolarHBondContact O-N 3.01Å; E453-R457 WeakPolarHBondContact O-CB 3.3Å; E453-R457 VanDerWaalsContact O-CG 3.3Å; E453-R457 WeakPolarHBondContact O-CG 3.5Å; E453-R457 PolarHBondContact O-N 3.33Å
454	E	77.5	Confident	75.6	Confident	82 Å²	82	63.8 Å²	63.8	38%	0.383	35%	0.349	S	S	.	.	H	α-helix	trans	-65.3	-43.7	174.7	-78.7	171.1	-176.4	0	0	111.6	H450 R451 E452 R457 Q458 K472	H450-E454 WeakPolarHBondContact O-CB 3.49Å; H450-E454 VanDerWaalsContact O-CG 3.28Å; H450-E454 WeakPolarHBondContact O-CG 3.09Å; H450-E454 PolarHBondContact O-N 3.38Å; R451-E454 PolarHBondContact O-N 2.88Å; E452-E454 VanDerWaalsContact C-N 3.33Å; E452-E454 PolarHBondContact O-N 2.95Å; E454-R457 PolarHBondContact O-N 3.35Å; E454-Q458 WeakPolarHBondContact O-CG 3.37Å; E454-Q458 PolarHBondContact O-N 3.11Å; E454-K472 WeakPolarHBondContact OE1-CE 3.32Å; E454-K472 IonicContact OE1-NZ 3.88Å; E454-K472 PolarHBondContact OE1-NZ 3.37Å; E454-K472 IonicContact OE2-NZ 3.26Å
455	K	81.7	Confident	73.9	Confident	77 Å²	77	69.5 Å²	69.5	34%	0.335	39%	0.387	S	S	.	.	H	α-helix	trans	-65	-43.5	175.8	-71	168.1	-178.9	168	0	111.9	R451 E452 R457 Q458 Q459	R451-K455 HydrophobicContact CG-CD 4.3Å; R451-K455 VanDerWaalsContact CZ-NZ 3.32Å; R451-K455 VanDerWaalsContact O-CG 3.3Å; R451-K455 WeakPolarHBondContact O-CG 3.31Å; R451-K455 PolarHBondContact O-N 2.79Å; E452-K455 PolarHBondContact O-N 3.4Å; K455-R457 VanDerWaalsContact C-N 3.32Å; K455-R457 PolarHBondContact O-N 2.98Å; K455-Q458 PolarHBondContact O-N 3.49Å; K455-Q459 WeakPolarHBondContact O-CB 3.16Å; K455-Q459 VanDerWaalsContact O-CG 3.31Å; K455-Q459 WeakPolarHBondContact O-CG 3.47Å; K455-Q459 PolarHBondContact O-N 3.47Å
456	E	80.5	Confident	71.7	Confident	107 Å²	107	76.3 Å²	76.3	50%	0.5	42%	0.423	S	S	.	.	H	α-helix	trans	-61.4	-41	177	-73.9	175.6	-178	0	0	111.1	E452 Q459 A460	E452-E456 WeakPolarHBondContact O-CB 3.44Å; E452-E456 WeakPolarHBondContact O-CG 3.47Å; E452-E456 PolarHBondContact O-N 3.13Å; E456-Q459 PolarHBondContact O-N 3.12Å; E456-A460 WeakPolarHBondContact O-CB 3.34Å; E456-A460 PolarHBondContact O-N 3.17Å
457	R	73.9	Confident	69.8	Low	129 Å²	129	81.7 Å²	81.7	49%	0.487	45%	0.452	S	S	.	.	H	α-helix	trans	-64.6	-40.5	174.3	-77.2	-178.1	-173.9	-147.2	0.3	112.8	E453 E454 K455 Q459 A460 N467	E453-R457 WeakPolarHBondContact O-CB 3.3Å; E453-R457 VanDerWaalsContact O-CG 3.3Å; E453-R457 WeakPolarHBondContact O-CG 3.5Å; E453-R457 PolarHBondContact O-N 3.33Å; E454-R457 PolarHBondContact O-N 3.35Å; K455-R457 VanDerWaalsContact C-N 3.32Å; K455-R457 PolarHBondContact O-N 2.98Å; R457-Q459 VanDerWaalsContact C-N 3.27Å; R457-Q459 PolarHBondContact O-N 3.43Å; R457-A460 PolarHBondContact O-N 2.95Å; R457-N467 PolarHBondContact NH1-O 3.36Å; R457-N467 VanDerWaalsContact NH1-O 3.09Å; R457-N467 PolarHBondContact NH2-O 2.83Å
458	Q	71.8	Confident	68.1	Low	135 Å²	135	85.7 Å²	85.7	63%	0.631	48%	0.48	S	S	*	.	H	α-helix	trans	-67.1	-29	177.4	-74.1	174.1	-3	0	0	112.5	E454 K455	E454-Q458 WeakPolarHBondContact O-CG 3.37Å; E454-Q458 PolarHBondContact O-N 3.11Å; K455-Q458 PolarHBondContact O-N 3.49Å
459	Q	73.8	Confident	66.5	Low	155 Å²	155	91 Å²	91	72%	0.724	51%	0.513	S	S	*	.	H	α-helix	trans	-89.1	-17.7	-179.7	-69.1	174.7	7.3	0	0	113.6	K455 E456 R457 P461	K455-Q459 WeakPolarHBondContact O-CB 3.16Å; K455-Q459 VanDerWaalsContact O-CG 3.31Å; K455-Q459 WeakPolarHBondContact O-CG 3.47Å; K455-Q459 PolarHBondContact O-N 3.47Å; E456-Q459 PolarHBondContact O-N 3.12Å; R457-Q459 VanDerWaalsContact C-N 3.27Å; R457-Q459 PolarHBondContact O-N 3.43Å; Q459-P461 VanDerWaalsContact O-CD 3.3Å; Q459-P461 WeakPolarHBondContact O-CD 3.47Å
460	A	68.4	Low	65.3	Low	51 Å²	51	93.5 Å²	93.5	42%	0.421	52%	0.523	S	S	.	.	S	Bend	trans	-74.6	113.4	179.7	0	0	0	0	0	111.7	E456 R457 G462	E456-A460 WeakPolarHBondContact O-CB 3.34Å; E456-A460 PolarHBondContact O-N 3.17Å; R457-A460 PolarHBondContact O-N 2.95Å; A460-G462 PolarHBondContact O-N 2.84Å
461	P	55.6	Low	64.3	Low	136 Å²	136	94.4 Å²	94.4	88%	0.883	54%	0.535	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.6	119.3	175.6	-1.6	16.4	0	0	0	109.4	Q459	Q459-P461 VanDerWaalsContact O-CD 3.3Å; Q459-P461 WeakPolarHBondContact O-CD 3.47Å
462	G	60	Low	63.5	Low	86 Å²	86	93 Å²	93	89%	0.887	53%	0.532	S	S	*	.	T	Hydrogen-bonded Turn	trans	91.7	20.5	176.4	0	0	0	0	0	116	A460 D464	A460-G462 PolarHBondContact O-N 2.84Å; G462-D464 PolarHBondContact O-N 2.79Å
463	G	46.9	Very low	62.6	Low	53 Å²	53	92 Å²	92	55%	0.546	53%	0.531	S	S	.	.			trans	-64.2	116.2	174.5	0	0	0	0	0	112.4	P465	G463-P465 WeakPolarHBondContact O-CD 3.06Å
464	D	48.2	Very low	62	Low	114 Å²	114	92.7 Å²	92.7	61%	0.61	54%	0.535	S	S	*	.			trans	-57.6	115.7	171.1	-168	-1.2	0	0	0	109.6	G462 D466	G462-D464 PolarHBondContact O-N 2.79Å; D464-D466 PolarHBondContact O-N 3.32Å; D464-D466 VanDerWaalsContact O-N 3.11Å; D464-D466 PolarHBondContact OD1-N 3.48Å
465	P	52.1	Low	61.8	Low	122 Å²	122	88.9 Å²	88.9	79%	0.792	52%	0.518	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.1	-13.9	-177.9	25.2	-33	0	0	0	112.8	G463	G463-P465 WeakPolarHBondContact O-CD 3.06Å
466	D	44.9	Very low	61.4	Low	144 Å²	144	85.3 Å²	85.3	77%	0.77	50%	0.502	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.5	-0.6	-171.7	-140.4	17	0	0	0	114.3	D464 S468	D464-D466 PolarHBondContact O-N 3.32Å; D464-D466 VanDerWaalsContact O-N 3.11Å; D464-D466 PolarHBondContact OD1-N 3.48Å; D466-S468 VanDerWaalsContact C-N 3.3Å; D466-S468 PolarHBondContact O-N 2.9Å
467	N	45.4	Very low	61.1	Low	117 Å²	117	80.8 Å²	80.8	63%	0.626	48%	0.483	S	S	*	.	S	Bend	trans	-76.1	87.2	173.4	-117.7	-11.8	0	0	0	110.2	R457 V469	R457-N467 PolarHBondContact NH1-O 3.36Å; R457-N467 VanDerWaalsContact NH1-O 3.09Å; R457-N467 PolarHBondContact NH2-O 2.83Å; N467-V469 PolarHBondContact O-N 2.87Å
468	S	47.3	Very low	61.4	Low	93 Å²	93	74.7 Å²	74.7	65%	0.65	46%	0.46	S	S	*	.			trans	-4.4	109.2	-177.5	70.7	0	0	0	0	113.6	D466 R470	D466-S468 VanDerWaalsContact C-N 3.3Å; D466-S468 PolarHBondContact O-N 2.9Å; S468-R470 VanDerWaalsContact C-N 3.33Å; S468-R470 PolarHBondContact O-N 2.96Å
469	V	53.4	Low	62	Low	125 Å²	125	68.2 Å²	68.2	76%	0.758	43%	0.43	S	S	*	.			trans	-49.5	102.9	164	178	0	0	0	0	106.8	N467 G471	N467-V469 PolarHBondContact O-N 2.87Å; V469-G471 PolarHBondContact O-N 3.22Å; V469-G471 VanDerWaalsContact O-N 3.08Å
470	R	61.2	Low	62.4	Low	53 Å²	53	61.1 Å²	61.1	20%	0.2	40%	0.397	C	S	.	.			trans	-62.3	119.1	-178.4	-175.5	168.6	165.2	-137.1	-5.4	106.6	S468 K472 D475	S468-R470 VanDerWaalsContact C-N 3.33Å; S468-R470 PolarHBondContact O-N 2.96Å; R470-K472 PolarHBondContact O-N 2.94Å; R470-K472 VanDerWaalsContact O-N 3.08Å; R470-D475 IonicContact CZ-OD1 3.1Å; R470-D475 IonicContact CZ-OD2 3.36Å; R470-D475 IonicContact NE-OD1 3.27Å; R470-D475 PolarHBondContact NE-OD1 3.31Å; R470-D475 IonicContact NE-OD2 3.71Å; R470-D475 PolarHBondContact NE-OD2 2.9Å; R470-D475 IonicContact NH1-OD2 2.86Å; R470-D475 IonicContact NH2-OD1 3.82Å; R470-D475 PolarHBondContact NH2-OD1 3.47Å; R470-D475 IonicContact NH2-OD2 3.88Å; R470-D475 PolarHBondContact NH2-OD2 3.02Å
471	G	62.3	Low	63.1	Low	31 Å²	31	58.7 Å²	58.7	32%	0.32	38%	0.377	S	S	.	.			trans	-66.1	114	-171.2	0	0	0	0	0	110	V469 G473 M474 D475	V469-G471 PolarHBondContact O-N 3.22Å; V469-G471 VanDerWaalsContact O-N 3.08Å; G471-G473 PolarHBondContact O-N 3.03Å; G471-M474 WeakPolarHBondContact O-CA 3.48Å; G471-M474 WeakPolarHBondContact O-CB 3.32Å; G471-M474 PolarHBondContact O-N 3.32Å; G471-D475 PolarHBondContact O-N 3.32Å
472	K	64.2	Low	64.7	Low	64 Å²	64	52.8 Å²	52.8	28%	0.278	34%	0.338	S	S	.	.	H	α-helix	trans	-48	-34.7	172.6	-62.4	-177.9	179.4	176.3	0	111.8	E454 R470 C476	E454-K472 WeakPolarHBondContact OE1-CE 3.32Å; E454-K472 IonicContact OE1-NZ 3.88Å; E454-K472 PolarHBondContact OE1-NZ 3.37Å; E454-K472 IonicContact OE2-NZ 3.26Å; R470-K472 PolarHBondContact O-N 2.94Å; R470-K472 VanDerWaalsContact O-N 3.08Å; K472-C476 WeakPolarHBondContact O-CB 3.39Å; K472-C476 PolarHBondContact O-N 3.43Å; K472-C476 VanDerWaalsContact O-N 3.1Å
473	G	64.1	Low	66	Low	15 Å²	15	49.6 Å²	49.6	16%	0.155	30%	0.301	C	S	.	.	H	α-helix	trans	-65.4	-35.9	174.1	0	0	0	0	0	114.6	G471 A477	G471-G473 PolarHBondContact O-N 3.03Å; G473-A477 VanDerWaalsContact O-CB 3.24Å; G473-A477 WeakPolarHBondContact O-CB 3.29Å; G473-A477 PolarHBondContact O-N 3.48Å
474	M	68.4	Low	68	Low	57 Å²	57	47.2 Å²	47.2	28%	0.281	28%	0.276	S	S	.	.	H	α-helix	trans	-69.3	-39.3	177.2	-174.2	-176.9	-56.8	0	0	111.4	M301 A309 G471 A477 T478	M301-M474 HydrophobicContact CE-CE 3.94Å; M301-M474 HydrophobicContact CE-CG 4.18Å; M301-M474 HydrophobicContact SD-CE 3.59Å; M301-M474 VanDerWaalsContact SD-CE 3.59Å; M301-M474 HydrophobicContact SD-CG 4.38Å; M301-M474 HydrophobicContact SD-SD 4.16Å; A309-M474 HydrophobicContact CB-SD 4.1Å; G471-M474 WeakPolarHBondContact O-CA 3.48Å; G471-M474 WeakPolarHBondContact O-CB 3.32Å; G471-M474 PolarHBondContact O-N 3.32Å; M474-A477 PolarHBondContact O-N 2.88Å; M474-T478 WeakPolarHBondContact O-CB 3.39Å; M474-T478 PolarHBondContact O-N 3.33Å; M474-T478 PolarHBondContact O-OG1 3.17Å
475	D	74.6	Confident	69.9	Low	3 Å²	3	44 Å²	44	2%	0.016	26%	0.258	C	S	.	.	H	α-helix	trans	-71.2	-40.6	179.5	-67.4	-25.6	0	0	0	111.4	I446 H450 R470 G471 T478 L479	I446-D475 HydrophobicContact CG2-CB 4.46Å; H450-D475 IonicContact CE1-OD2 2.65Å; H450-D475 PolarHBondContact CE1-OD2 3.49Å; H450-D475 IonicContact NE2-OD2 2.68Å; H450-D475 PolarHBondContact NE2-OD2 3.28Å; R470-D475 IonicContact CZ-OD1 3.1Å; R470-D475 IonicContact CZ-OD2 3.36Å; R470-D475 IonicContact NE-OD1 3.27Å; R470-D475 PolarHBondContact NE-OD1 3.31Å; R470-D475 IonicContact NE-OD2 3.71Å; R470-D475 PolarHBondContact NE-OD2 2.9Å; R470-D475 IonicContact NH1-OD2 2.86Å; R470-D475 IonicContact NH2-OD1 3.82Å; R470-D475 PolarHBondContact NH2-OD1 3.47Å; R470-D475 IonicContact NH2-OD2 3.88Å; R470-D475 PolarHBondContact NH2-OD2 3.02Å; G471-D475 PolarHBondContact O-N 3.32Å; D475-T478 PolarHBondContact O-N 2.67Å; D475-L479 WeakPolarHBondContact O-CB 3.48Å; D475-L479 PolarHBondContact O-N 3.34Å
476	C	73.3	Confident	71.8	Confident	1 Å²	1	38.2 Å²	38.2	1%	0.007	22%	0.221	C	C	.	.	H	α-helix	trans	-59.9	-47.8	169.7	-174.7	0	0	0	0	111.4	K472 T478 L479 T480	K472-C476 WeakPolarHBondContact O-CB 3.39Å; K472-C476 PolarHBondContact O-N 3.43Å; K472-C476 VanDerWaalsContact O-N 3.1Å; C476-T478 VanDerWaalsContact C-N 3.31Å; C476-T478 PolarHBondContact O-N 3Å; C476-L479 WeakPolarHBondContact O-CB 3.15Å; C476-L479 PolarHBondContact O-N 3.01Å; C476-T480 PolarHBondContact O-N 3.25Å; C476-T480 PolarHBondContact O-OG1 3.08Å; C476-T480 VanDerWaalsContact O-OG1 3.09Å
477	A	73.5	Confident	73.9	Confident	12 Å²	12	32.4 Å²	32.4	10%	0.099	19%	0.189	C	C	.	.	H	α-helix	trans	-61.4	-39.6	177.4	0	0	0	0	0	112.1	G473 M474 T480 C481	G473-A477 VanDerWaalsContact O-CB 3.24Å; G473-A477 WeakPolarHBondContact O-CB 3.29Å; G473-A477 PolarHBondContact O-N 3.48Å; M474-A477 PolarHBondContact O-N 2.88Å; A477-T480 PolarHBondContact O-N 3.09Å; A477-C481 WeakPolarHBondContact O-CB 3.04Å; A477-C481 PolarHBondContact O-N 3.26Å; A477-C481 PolarHBondContact O-SG 3.4Å
478	T	79.8	Confident	75.9	Confident	1 Å²	1	28.5 Å²	28.5	1%	0.006	17%	0.168	C	C	.	.	H	α-helix	trans	-64.9	-42.3	177.2	-57.4	0	0	0	0	111	L310 M313 M474 D475 C476 C481 M482	L310-T478 HydrophobicContact CD2-CG2 3.34Å; L310-T478 HydrophobicContact CG-CG2 4.07Å; M313-T478 HydrophobicContact CE-CG2 3.88Å; M474-T478 WeakPolarHBondContact O-CB 3.39Å; M474-T478 PolarHBondContact O-N 3.33Å; M474-T478 PolarHBondContact O-OG1 3.17Å; D475-T478 PolarHBondContact O-N 2.67Å; C476-T478 VanDerWaalsContact C-N 3.31Å; C476-T478 PolarHBondContact O-N 3Å; T478-C481 WeakPolarHBondContact O-CB 3.45Å; T478-C481 PolarHBondContact O-N 3.49Å; T478-M482 HydrophobicContact CG2-CE 4.11Å; T478-M482 WeakPolarHBondContact O-CE 3.37Å; T478-M482 PolarHBondContact O-N 3.48Å
479	L	84.2	Confident	77.9	Confident	0 Å²	0	28.3 Å²	28.3	0%	0	16%	0.159	C	C	.	.	H	α-helix	trans	-62.5	-45.5	175.1	-169.8	69.9	0	0	0	110.9	H324 P442 F443 I446 D475 C476 C481 M482	H324-L479 HydrophobicContact CB-CD1 3.55Å; H324-L479 VanDerWaalsContact CD2-CD1 3.47Å; H324-L479 WeakPolarHBondContact CD2-CD1 3.35Å; H324-L479 PolarHBondContact CD2-O 3.5Å; H324-L479 VanDerWaalsContact CG-CD1 3.49Å; P442-L479 HydrophobicContact CB-CD1 4.29Å; P442-L479 HydrophobicContact CB-CD2 3.68Å; F443-L479 HydrophobicContact CD1-CD2 3.67Å; F443-L479 HydrophobicContact CD2-CD2 4.12Å; F443-L479 HydrophobicContact CE1-CB 4.47Å; F443-L479 HydrophobicContact CE1-CD2 3.57Å; F443-L479 HydrophobicContact CE1-CG 4.33Å; F443-L479 HydrophobicContact CE2-CD2 4.01Å; F443-L479 HydrophobicContact CG-CD2 3.94Å; F443-L479 HydrophobicContact CZ-CD2 3.73Å; F443-L479 HydrophobicContact CZ-CG 4.33Å; I446-L479 HydrophobicContact CD1-CB 3.93Å; I446-L479 HydrophobicContact CD1-CD1 4.47Å; I446-L479 HydrophobicContact CD1-CD2 3.47Å; I446-L479 VanDerWaalsContact CD1-CD2 3.47Å; I446-L479 HydrophobicContact CD1-CG 4.15Å; D475-L479 WeakPolarHBondContact O-CB 3.48Å; D475-L479 PolarHBondContact O-N 3.34Å; C476-L479 WeakPolarHBondContact O-CB 3.15Å; C476-L479 PolarHBondContact O-N 3.01Å; L479-C481 VanDerWaalsContact C-N 3.32Å; L479-C481 PolarHBondContact O-N 3.1Å; L479-M482 VanDerWaalsContact O-CB 3.29Å; L479-M482 WeakPolarHBondContact O-CB 3.43Å; L479-M482 PolarHBondContact O-N 3.29Å; L479-M482 VanDerWaalsContact O-N 3.08Å
480	T	82.3	Confident	79.5	Confident	5 Å²	5	22.7 Å²	22.7	3%	0.031	13%	0.125	C	C	.	.	H	α-helix	trans	-65.5	-33.4	176.6	-48.3	0	0	0	0	112.2	C476 A477 M482 V483	C476-T480 PolarHBondContact O-N 3.25Å; C476-T480 PolarHBondContact O-OG1 3.08Å; C476-T480 VanDerWaalsContact O-OG1 3.09Å; A477-T480 PolarHBondContact O-N 3.09Å; T480-M482 PolarHBondContact O-N 3.42Å; T480-V483 VanDerWaalsContact O-CB 3.28Å; T480-V483 WeakPolarHBondContact O-CB 3.34Å; T480-V483 WeakPolarHBondContact O-CG2 3.29Å; T480-V483 PolarHBondContact O-N 3.17Å
481	C	83.1	Confident	80.4	Confident	1 Å²	1	22.3 Å²	22.3	1%	0.007	14%	0.138	C	C	.	.	H	α-helix	trans	-60.9	-27.3	173.1	-69.7	0	0	0	0	112.5	A477 T478 L479 V483 Q484 L485	A477-C481 WeakPolarHBondContact O-CB 3.04Å; A477-C481 PolarHBondContact O-N 3.26Å; A477-C481 PolarHBondContact O-SG 3.4Å; T478-C481 WeakPolarHBondContact O-CB 3.45Å; T478-C481 PolarHBondContact O-N 3.49Å; L479-C481 VanDerWaalsContact C-N 3.32Å; L479-C481 PolarHBondContact O-N 3.1Å; C481-V483 VanDerWaalsContact C-N 3.26Å; C481-V483 PolarHBondContact O-N 3.27Å; C481-Q484 PolarHBondContact O-N 2.97Å; C481-L485 PolarHBondContact O-N 2.97Å
482	M	89.2	Confident	81.3	Confident	11 Å²	11	23.1 Å²	23.1	5%	0.054	15%	0.146	C	C	.	.	H	α-helix	trans	-66.9	-28.6	175.1	-59.4	-60.2	122.3	0	0	112.2	L310 C321 L325 T478 L479 T480 L485 A486	L310-M482 HydrophobicContact CD1-CE 4.11Å; L310-M482 HydrophobicContact CD2-CE 3.57Å; L310-M482 HydrophobicContact CG-CE 4.46Å; C321-M482 HydrophobicContact CB-CG 4Å; C321-M482 HydrophobicContact CB-SD 4.21Å; L325-M482 HydrophobicContact CB-CB 4.15Å; L325-M482 HydrophobicContact CB-SD 4.4Å; L325-M482 VanDerWaalsContact CD1-O 3.27Å; L325-M482 WeakPolarHBondContact CD1-O 3.43Å; T478-M482 HydrophobicContact CG2-CE 4.11Å; T478-M482 WeakPolarHBondContact O-CE 3.37Å; T478-M482 PolarHBondContact O-N 3.48Å; L479-M482 VanDerWaalsContact O-CB 3.29Å; L479-M482 WeakPolarHBondContact O-CB 3.43Å; L479-M482 PolarHBondContact O-N 3.29Å; L479-M482 VanDerWaalsContact O-N 3.08Å; T480-M482 PolarHBondContact O-N 3.42Å; M482-L485 PolarHBondContact O-N 3.42Å; M482-L485 HydrophobicContact SD-CD2 4.48Å; M482-A486 WeakPolarHBondContact O-CB 3.38Å; M482-A486 PolarHBondContact O-N 3.04Å
483	V	88.9	Confident	82.2	Confident	20 Å²	20	21.8 Å²	21.8	12%	0.121	15%	0.151	C	C	.	.	H	α-helix	trans	-65.7	-46.4	174.7	-171.8	0	0	0	0	110.2	W328 T480 C481 L485 A486 Q487	W328-V483 HydrophobicContact CD2-CG1 3.86Å; W328-V483 HydrophobicContact CD2-CG2 4.19Å; W328-V483 HydrophobicContact CE3-CG1 4.08Å; W328-V483 HydrophobicContact CG-CB 4.4Å; W328-V483 HydrophobicContact CG-CG1 4.13Å; W328-V483 HydrophobicContact CG-CG2 4.06Å; T480-V483 VanDerWaalsContact O-CB 3.28Å; T480-V483 WeakPolarHBondContact O-CB 3.34Å; T480-V483 WeakPolarHBondContact O-CG2 3.29Å; T480-V483 PolarHBondContact O-N 3.17Å; C481-V483 VanDerWaalsContact C-N 3.26Å; C481-V483 PolarHBondContact O-N 3.27Å; V483-L485 VanDerWaalsContact C-N 3.32Å; V483-L485 PolarHBondContact O-N 2.94Å; V483-A486 WeakPolarHBondContact O-CB 3.43Å; V483-A486 PolarHBondContact O-N 3.28Å; V483-A486 VanDerWaalsContact O-N 3.12Å; V483-Q487 PolarHBondContact O-N 3.16Å
484	Q	88.1	Confident	83	Confident	2 Å²	2	21.5 Å²	21.5	1%	0.009	15%	0.145	C	C	.	.	H	α-helix	trans	-62	-42.5	177.3	-59.8	-63	-43.7	0	0	111.1	P78 F82 D157 C481 A486 Q487 I488	P78-Q484 VanDerWaalsContact CA-OE1 3.27Å; P78-Q484 PolarHBondContact O-OE1 2.91Å; F82-Q484 HydrophobicContact CB-CB 4.17Å; D157-Q484 PolarHBondContact OD2-NE2 3.18Å; C481-Q484 PolarHBondContact O-N 2.97Å; Q484-A486 VanDerWaalsContact C-N 3.34Å; Q484-A486 PolarHBondContact O-N 3.45Å; Q484-Q487 VanDerWaalsContact CD-OE1 3.28Å; Q484-Q487 PolarHBondContact O-N 3.11Å; Q484-I488 VanDerWaalsContact O-CG1 3.32Å; Q484-I488 WeakPolarHBondContact O-CG1 3.28Å; Q484-I488 PolarHBondContact O-N 2.83Å
485	L	88.7	Confident	83.3	Confident	47 Å²	47	20.6 Å²	20.6	25%	0.246	15%	0.15	C	C	.	.	H	α-helix	trans	-62.7	-40	174.1	-175.2	61.1	0	0	0	112	F82 L325 C481 M482 V483 I488 L489	F82-L485 HydrophobicContact CD2-CB 4.22Å; F82-L485 HydrophobicContact CE2-CB 4.21Å; F82-L485 HydrophobicContact CE2-CD1 4.3Å; L325-L485 HydrophobicContact CD1-CB 3.88Å; L325-L485 HydrophobicContact CD1-CD2 3.91Å; L325-L485 HydrophobicContact CD1-CG 3.8Å; L325-L485 HydrophobicContact CD2-CD2 3.9Å; C481-L485 PolarHBondContact O-N 2.97Å; M482-L485 PolarHBondContact O-N 3.42Å; M482-L485 HydrophobicContact SD-CD2 4.48Å; V483-L485 VanDerWaalsContact C-N 3.32Å; V483-L485 PolarHBondContact O-N 2.94Å; L485-I488 PolarHBondContact O-N 3.09Å; L485-L489 HydrophobicContact CG-CD1 4.41Å; L485-L489 VanDerWaalsContact O-CG 3.3Å; L485-L489 WeakPolarHBondContact O-CG 3.45Å; L485-L489 PolarHBondContact O-N 2.89Å
486	A	91.3	Very high	83.7	Confident	0 Å²	0	27.6 Å²	27.6	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-61.6	-44.5	173.9	0	0	0	0	0	111.9	L325 W328 T329 L332 M482 V483 Q484 I488 L489 V490	L325-A486 HydrophobicContact CD1-CB 4.03Å; W328-A486 HydrophobicContact CB-CB 3.59Å; T329-A486 WeakPolarHBondContact OG1-CB 3.34Å; L332-A486 HydrophobicContact CD1-CB 3.99Å; M482-A486 WeakPolarHBondContact O-CB 3.38Å; M482-A486 PolarHBondContact O-N 3.04Å; V483-A486 WeakPolarHBondContact O-CB 3.43Å; V483-A486 PolarHBondContact O-N 3.28Å; V483-A486 VanDerWaalsContact O-N 3.12Å; Q484-A486 VanDerWaalsContact C-N 3.34Å; Q484-A486 PolarHBondContact O-N 3.45Å; A486-I488 VanDerWaalsContact C-N 3.34Å; A486-I488 PolarHBondContact O-N 3.32Å; A486-L489 PolarHBondContact O-N 3.28Å; A486-V490 WeakPolarHBondContact O-CB 3.47Å; A486-V490 VanDerWaalsContact O-CG2 3.3Å; A486-V490 WeakPolarHBondContact O-CG2 3.36Å; A486-V490 PolarHBondContact O-N 3.06Å
487	Q	88.7	Confident	84.4	Confident	23 Å²	23	30.3 Å²	30.3	11%	0.107	20%	0.195	C	C	.	.	H	α-helix	trans	-60.2	-42.6	175.9	-71.9	169.7	-52.7	0	0	111.8	P78 L332 V483 Q484 V490 G491	P78-Q487 HydrophobicContact CB-CB 3.77Å; P78-Q487 HydrophobicContact CG-CB 3.68Å; P78-Q487 HydrophobicContact CG-CG 4.47Å; L332-Q487 HydrophobicContact CD1-CB 4.32Å; L332-Q487 HydrophobicContact CD1-CG 3.42Å; L332-Q487 VanDerWaalsContact CD1-CG 3.42Å; L332-Q487 HydrophobicContact CD2-CG 4.41Å; V483-Q487 PolarHBondContact O-N 3.16Å; Q484-Q487 VanDerWaalsContact CD-OE1 3.28Å; Q484-Q487 PolarHBondContact O-N 3.11Å; Q487-V490 PolarHBondContact O-N 3.46Å; Q487-G491 PolarHBondContact O-N 2.94Å
488	I	87.8	Confident	84.9	Confident	34 Å²	34	31 Å²	31	17%	0.174	20%	0.198	C	C	.	.	H	α-helix	trans	-61.5	-46.8	175.3	-66.8	167.9	0	0	0	110.8	F75 P78 I79 F82 Q484 L485 A486 G492	F75-I488 HydrophobicContact CE2-CB 4.35Å; F75-I488 HydrophobicContact CE2-CG2 3.81Å; F75-I488 HydrophobicContact CZ-CG2 3.91Å; P78-I488 HydrophobicContact CB-CD1 4.48Å; P78-I488 HydrophobicContact CB-CG1 3.65Å; I79-I488 HydrophobicContact CG1-CD1 4.26Å; I79-I488 HydrophobicContact CG1-CG1 4.34Å; F82-I488 HydrophobicContact CB-CD1 3.87Å; F82-I488 HydrophobicContact CG-CD1 4.27Å; Q484-I488 VanDerWaalsContact O-CG1 3.32Å; Q484-I488 WeakPolarHBondContact O-CG1 3.28Å; Q484-I488 PolarHBondContact O-N 2.83Å; L485-I488 PolarHBondContact O-N 3.09Å; A486-I488 VanDerWaalsContact C-N 3.34Å; A486-I488 PolarHBondContact O-N 3.32Å; I488-G492 PolarHBondContact O-N 2.95Å
489	L	89.6	Confident	85.1	Confident	90 Å²	90	37.4 Å²	37.4	47%	0.471	23%	0.232	S	C	.	.	H	α-helix	trans	-62.4	-45	-179.9	-72.5	174	0	0	0	111.8	L325 L485 A486 G493	L325-L489 HydrophobicContact CD1-CD1 4.21Å; L485-L489 HydrophobicContact CG-CD1 4.41Å; L485-L489 VanDerWaalsContact O-CG 3.3Å; L485-L489 WeakPolarHBondContact O-CG 3.45Å; L485-L489 PolarHBondContact O-N 2.89Å; A486-L489 PolarHBondContact O-N 3.28Å; L489-G493 WeakPolarHBondContact O-CA 2.95Å; L489-G493 PolarHBondContact O-N 3.25Å
490	V	87.2	Confident	85.3	Confident	6 Å²	6	41.9 Å²	41.9	4%	0.036	26%	0.26	C	S	.	.	H	α-helix	trans	-68.9	-48.4	179.1	175.2	0	0	0	0	110.7	T329 L332 L336 A486 Q487 G492 L494	T329-V490 HydrophobicContact CG2-CG2 3.89Å; T329-V490 WeakPolarHBondContact O-CG2 3.5Å; L332-V490 HydrophobicContact CB-CG2 4.26Å; L336-V490 HydrophobicContact CD1-CG1 3.84Å; A486-V490 WeakPolarHBondContact O-CB 3.47Å; A486-V490 VanDerWaalsContact O-CG2 3.3Å; A486-V490 WeakPolarHBondContact O-CG2 3.36Å; A486-V490 PolarHBondContact O-N 3.06Å; Q487-V490 PolarHBondContact O-N 3.46Å; V490-G492 PolarHBondContact O-N 3.47Å; V490-L494 HydrophobicContact CG1-CB 4.27Å; V490-L494 HydrophobicContact CG1-CD2 4Å; V490-L494 WeakPolarHBondContact O-CB 3.38Å; V490-L494 PolarHBondContact O-N 3.46Å
491	G	80	Confident	85.7	Confident	46 Å²	46	44.1 Å²	44.1	47%	0.474	28%	0.279	S	S	.	.	H	α-helix	trans	-63.2	-39.1	-178.6	0	0	0	0	0	113.3	Q487	Q487-G491 PolarHBondContact O-N 2.94Å
492	G	79.7	Confident	85.7	Confident	48 Å²	48	47.5 Å²	47.5	50%	0.495	31%	0.314	S	S	.	.	H	α-helix	trans	-82.5	-35.8	178.5	0	0	0	0	0	114.4	I488 V490	I488-G492 PolarHBondContact O-N 2.95Å; V490-G492 PolarHBondContact O-N 3.47Å
493	G	83.1	Confident	85.7	Confident	36 Å²	36	49.4 Å²	49.4	37%	0.371	33%	0.326	S	S	.	.	H	α-helix	trans	-93.5	-37	-171.3	0	0	0	0	0	114.6	L489 F496 L497	L489-G493 WeakPolarHBondContact O-CA 2.95Å; L489-G493 PolarHBondContact O-N 3.25Å; G493-F496 PolarHBondContact O-N 3.34Å; G493-L497 PolarHBondContact O-N 3.25Å; G493-L497 VanDerWaalsContact O-N 3.13Å
494	L	81.2	Confident	85.5	Confident	8 Å²	8	48.7 Å²	48.7	4%	0.042	32%	0.322	C	S	.	.	H	α-helix	trans	-76	-33.5	-166.8	-160.2	68.9	0	0	0	112.7	F337 V490 F496 L497 V498 V507 T510	F337-L494 HydrophobicContact CD2-CD2 3.34Å; F337-L494 HydrophobicContact CD2-CG 4.41Å; F337-L494 HydrophobicContact CE2-CB 4.11Å; F337-L494 HydrophobicContact CE2-CD2 3.29Å; F337-L494 HydrophobicContact CE2-CG 4.04Å; F337-L494 HydrophobicContact CG-CD2 4.28Å; F337-L494 HydrophobicContact CZ-CB 4.45Å; F337-L494 HydrophobicContact CZ-CD2 4.19Å; V490-L494 HydrophobicContact CG1-CB 4.27Å; V490-L494 HydrophobicContact CG1-CD2 4Å; V490-L494 WeakPolarHBondContact O-CB 3.38Å; V490-L494 PolarHBondContact O-N 3.46Å; L494-F496 VanDerWaalsContact C-N 3.34Å; L494-F496 PolarHBondContact O-N 3.12Å; L494-L497 HydrophobicContact CD1-CB 4.5Å; L494-L497 HydrophobicContact CD1-CD2 4.27Å; L494-L497 WeakPolarHBondContact O-CB 3.49Å; L494-L497 PolarHBondContact O-N 3.44Å; L494-L497 VanDerWaalsContact O-N 3.12Å; L494-V498 WeakPolarHBondContact O-CG2 3.46Å; L494-V498 PolarHBondContact O-N 2.96Å; L494-V507 HydrophobicContact CD1-CG1 4.48Å; L494-V507 HydrophobicContact CD1-CG2 4.27Å; L494-V507 HydrophobicContact CD2-CB 4.13Å; L494-V507 HydrophobicContact CD2-CG1 3.4Å; L494-V507 VanDerWaalsContact CD2-CG1 3.4Å; L494-V507 HydrophobicContact CD2-CG2 3.8Å; L494-V507 HydrophobicContact CG-CG1 4.31Å; L494-V507 HydrophobicContact CG-CG2 3.91Å; L494-T510 HydrophobicContact CD1-CG2 4.42Å
495	G	75.1	Confident	85.6	Confident	38 Å²	38	50 Å²	50	39%	0.392	33%	0.33	S	S	.	.	H	α-helix	trans	-61.6	-41.2	173.4	0	0	0	0	0	112.7	L497 V498 N499	G495-L497 VanDerWaalsContact C-N 3.29Å; G495-L497 PolarHBondContact O-N 2.91Å; G495-V498 PolarHBondContact O-N 3.33Å; G495-N499 WeakPolarHBondContact O-CB 3.48Å; G495-N499 PolarHBondContact O-N 3.47Å
496	F	84.2	Confident	85.8	Confident	151 Å²	151	49.2 Å²	49.2	66%	0.662	33%	0.327	S	S	*	.	H	α-helix	trans	-61.9	-40.3	172.6	174.1	-96.5	0	0	0	111.6	G493 L494 N499 T500	G493-F496 PolarHBondContact O-N 3.34Å; L494-F496 VanDerWaalsContact C-N 3.34Å; L494-F496 PolarHBondContact O-N 3.12Å; F496-N499 PolarHBondContact O-N 3.06Å; F496-T500 WeakPolarHBondContact O-CB 3.28Å; F496-T500 PolarHBondContact O-N 3.48Å; F496-T500 PolarHBondContact O-OG1 2.97Å
497	L	86.7	Confident	85.6	Confident	58 Å²	58	49.3 Å²	49.3	30%	0.304	33%	0.327	S	S	.	.	H	α-helix	trans	-67.3	-41.7	-179.7	-165.3	148.8	0	0	0	111.7	G493 L494 G495 T500 A501 V506	G493-L497 PolarHBondContact O-N 3.25Å; G493-L497 VanDerWaalsContact O-N 3.13Å; L494-L497 HydrophobicContact CD1-CB 4.5Å; L494-L497 HydrophobicContact CD1-CD2 4.27Å; L494-L497 WeakPolarHBondContact O-CB 3.49Å; L494-L497 PolarHBondContact O-N 3.44Å; L494-L497 VanDerWaalsContact O-N 3.12Å; G495-L497 VanDerWaalsContact C-N 3.29Å; G495-L497 PolarHBondContact O-N 2.91Å; L497-T500 PolarHBondContact O-N 2.61Å; L497-A501 VanDerWaalsContact O-CB 3.3Å; L497-A501 WeakPolarHBondContact O-CB 3.39Å; L497-A501 PolarHBondContact O-N 3.31Å; L497-V506 HydrophobicContact CD2-CB 3.86Å; L497-V506 HydrophobicContact CD2-CG1 3.32Å; L497-V506 HydrophobicContact CD2-CG2 3.29Å; L497-V506 HydrophobicContact CG-CG2 4.49Å
498	V	83.8	Confident	85.8	Confident	26 Å²	26	48.3 Å²	48.3	16%	0.158	32%	0.323	C	S	.	.	H	α-helix	trans	-61.9	-47.5	171.8	172.5	0	0	0	0	111.3	L494 G495 T500 A501 G502 V504 V506 V507	L494-V498 WeakPolarHBondContact O-CG2 3.46Å; L494-V498 PolarHBondContact O-N 2.96Å; G495-V498 PolarHBondContact O-N 3.33Å; V498-T500 VanDerWaalsContact C-N 3.3Å; V498-T500 PolarHBondContact O-N 2.9Å; V498-A501 PolarHBondContact O-N 3.25Å; V498-G502 PolarHBondContact O-N 2.86Å; V498-V504 HydrophobicContact CG1-CG1 3.96Å; V498-V506 HydrophobicContact CG2-CG1 4.02Å; V498-V507 HydrophobicContact CG2-CG2 3.32Å
499	N	83.9	Confident	86	Confident	135 Å²	135	50.9 Å²	50.9	72%	0.722	34%	0.336	S	S	*	.	H	α-helix	trans	-63.1	-37	179.5	-173.1	57.9	0	0	0	112.4	G495 F496	G495-N499 WeakPolarHBondContact O-CB 3.48Å; G495-N499 PolarHBondContact O-N 3.47Å; F496-N499 PolarHBondContact O-N 3.06Å
500	T	89.1	Confident	86.2	Confident	95 Å²	95	48.3 Å²	48.3	58%	0.583	32%	0.324	S	S	*	.	H	α-helix	trans	-73.2	-38.8	178.1	-55.1	0	0	0	0	112.1	F496 L497 V498	F496-T500 WeakPolarHBondContact O-CB 3.28Å; F496-T500 PolarHBondContact O-N 3.48Å; F496-T500 PolarHBondContact O-OG1 2.97Å; L497-T500 PolarHBondContact O-N 2.61Å; V498-T500 VanDerWaalsContact C-N 3.3Å; V498-T500 PolarHBondContact O-N 2.9Å
501	A	90	Very high	86.6	Confident	51 Å²	51	48 Å²	48	42%	0.421	32%	0.323	S	S	.	.	H	α-helix	trans	-78.3	-20.6	178.5	0	0	0	0	0	113.2	L497 V498 T503 V506	L497-A501 VanDerWaalsContact O-CB 3.3Å; L497-A501 WeakPolarHBondContact O-CB 3.39Å; L497-A501 PolarHBondContact O-N 3.31Å; V498-A501 PolarHBondContact O-N 3.25Å; A501-T503 HydrophobicContact CB-CG2 4.29Å; A501-T503 PolarHBondContact O-N 2.91Å; A501-V506 HydrophobicContact CB-CB 3.79Å; A501-V506 HydrophobicContact CB-CG1 3.88Å; A501-V506 HydrophobicContact CB-CG2 3.83Å
502	G	84.5	Confident	87.3	Confident	72 Å²	72	46.5 Å²	46.5	74%	0.742	31%	0.305	S	S	*	.	T	Hydrogen-bonded Turn	trans	69.7	13.1	-175.9	0	0	0	0	0	114.2	V498	V498-G502 PolarHBondContact O-N 2.86Å
503	T	87.9	Confident	88.1	Confident	52 Å²	52	46.4 Å²	46.4	32%	0.319	30%	0.299	S	S	.	.	S	Bend	trans	-152.9	145.6	-177.3	-177.7	0	0	0	0	111.4	A501 V505 V506	A501-T503 HydrophobicContact CB-CG2 4.29Å; A501-T503 PolarHBondContact O-N 2.91Å; T503-V505 VanDerWaalsContact C-N 3.3Å; T503-V505 HydrophobicContact CG2-CB 4.25Å; T503-V505 WeakPolarHBondContact OG1-CG2 3.49Å; T503-V505 PolarHBondContact OG1-N 3.3Å; T503-V506 WeakPolarHBondContact O-CG1 3.21Å
504	V	85.2	Confident	88.8	Confident	4 Å²	4	46.2 Å²	46.2	2%	0.024	29%	0.29	C	S	.	.	T	Hydrogen-bonded Turn	trans	-77.8	-12.9	175.5	-59.8	0	0	0	0	113.2	D340 F341 Q344 I345 V498 V506 V507	D340-V504 WeakPolarHBondContact OD2-CG1 3.25Å; F341-V504 HydrophobicContact CB-CG2 4.45Å; F341-V504 HydrophobicContact CD2-CG2 4.42Å; Q344-V504 HydrophobicContact CB-CG2 4.08Å; I345-V504 HydrophobicContact CD1-CG2 3.82Å; I345-V504 HydrophobicContact CG1-CG2 3.43Å; I345-V504 VanDerWaalsContact CG1-CG2 3.43Å; V498-V504 HydrophobicContact CG1-CG1 3.96Å; V504-V506 PolarHBondContact O-N 2.67Å; V504-V506 VanDerWaalsContact O-N 3.17Å; V504-V507 VanDerWaalsContact O-CB 3.3Å; V504-V507 WeakPolarHBondContact O-CB 3.34Å; V504-V507 WeakPolarHBondContact O-CG2 3.46Å; V504-V507 PolarHBondContact O-N 2.89Å
505	V	90.6	Very high	89.5	Confident	30 Å²	30	45.8 Å²	45.8	18%	0.182	29%	0.288	C	S	.	.	H	α-helix	trans	-56.5	-34.1	175.1	178.2	0	0	0	0	111.6	F341 I345 T503 V507 V508 I509	F341-V505 HydrophobicContact CE2-CG2 4.23Å; I345-V505 HydrophobicContact CB-CG2 4.34Å; I345-V505 HydrophobicContact CD1-CG2 3.56Å; I345-V505 HydrophobicContact CG1-CG2 3.63Å; I345-V505 HydrophobicContact CG2-CG2 3.79Å; T503-V505 VanDerWaalsContact C-N 3.3Å; T503-V505 HydrophobicContact CG2-CB 4.25Å; T503-V505 WeakPolarHBondContact OG1-CG2 3.49Å; T503-V505 PolarHBondContact OG1-N 3.3Å; V505-V507 PolarHBondContact O-N 3.35Å; V505-V507 VanDerWaalsContact O-N 3.1Å; V505-V508 PolarHBondContact O-N 3.04Å; V505-V508 VanDerWaalsContact O-N 3.11Å; V505-I509 HydrophobicContact CG1-CD1 3.79Å; V505-I509 HydrophobicContact CG1-CG1 4.18Å; V505-I509 PolarHBondContact O-N 3.38Å; V505-I509 VanDerWaalsContact O-N 3.14Å
506	V	91.4	Very high	90.6	Very high	30 Å²	30	47 Å²	47	18%	0.182	29%	0.285	C	S	.	.	H	α-helix	trans	-57.3	-28.1	179.9	78.1	0	0	0	0	112.2	L497 V498 A501 T503 V504 T510	L497-V506 HydrophobicContact CD2-CB 3.86Å; L497-V506 HydrophobicContact CD2-CG1 3.32Å; L497-V506 HydrophobicContact CD2-CG2 3.29Å; L497-V506 HydrophobicContact CG-CG2 4.49Å; V498-V506 HydrophobicContact CG2-CG1 4.02Å; A501-V506 HydrophobicContact CB-CB 3.79Å; A501-V506 HydrophobicContact CB-CG1 3.88Å; A501-V506 HydrophobicContact CB-CG2 3.83Å; T503-V506 WeakPolarHBondContact O-CG1 3.21Å; V504-V506 PolarHBondContact O-N 2.67Å; V504-V506 VanDerWaalsContact O-N 3.17Å; V506-T510 VanDerWaalsContact O-CB 3.24Å; V506-T510 WeakPolarHBondContact O-CB 3.32Å; V506-T510 PolarHBondContact O-N 2.92Å; V506-T510 PolarHBondContact O-OG1 3.34Å
507	V	88.6	Confident	91.2	Very high	2 Å²	2	44.8 Å²	44.8	1%	0.012	28%	0.279	C	S	.	.	H	α-helix	trans	-66	-48.9	178.4	176.1	0	0	0	0	110.8	S333 F337 L494 V498 V504 V505 I509 T510 A511	S333-V507 WeakPolarHBondContact O-CG1 3.27Å; F337-V507 HydrophobicContact CB-CB 4.37Å; F337-V507 HydrophobicContact CB-CG1 3.86Å; F337-V507 HydrophobicContact CB-CG2 4.23Å; F337-V507 HydrophobicContact CD1-CG2 4.46Å; F337-V507 HydrophobicContact CD2-CG1 4.14Å; F337-V507 HydrophobicContact CD2-CG2 4.46Å; F337-V507 HydrophobicContact CG-CG1 4.2Å; F337-V507 HydrophobicContact CG-CG2 4.13Å; L494-V507 HydrophobicContact CD1-CG1 4.48Å; L494-V507 HydrophobicContact CD1-CG2 4.27Å; L494-V507 HydrophobicContact CD2-CB 4.13Å; L494-V507 HydrophobicContact CD2-CG1 3.4Å; L494-V507 VanDerWaalsContact CD2-CG1 3.4Å; L494-V507 HydrophobicContact CD2-CG2 3.8Å; L494-V507 HydrophobicContact CG-CG1 4.31Å; L494-V507 HydrophobicContact CG-CG2 3.91Å; V498-V507 HydrophobicContact CG2-CG2 3.32Å; V504-V507 VanDerWaalsContact O-CB 3.3Å; V504-V507 WeakPolarHBondContact O-CB 3.34Å; V504-V507 WeakPolarHBondContact O-CG2 3.46Å; V504-V507 PolarHBondContact O-N 2.89Å; V505-V507 PolarHBondContact O-N 3.35Å; V505-V507 VanDerWaalsContact O-N 3.1Å; V507-I509 VanDerWaalsContact C-N 3.34Å; V507-I509 PolarHBondContact O-N 3.46Å; V507-T510 PolarHBondContact O-N 3.17Å; V507-A511 WeakPolarHBondContact O-CB 3.37Å; V507-A511 PolarHBondContact O-N 2.99Å
508	V	92.1	Very high	91.6	Very high	2 Å²	2	42 Å²	42	1%	0.012	27%	0.265	C	S	.	.	H	α-helix	trans	-66.7	-39.4	-179.2	179.9	0	0	0	0	110.6	F341 T412 I415 V505 A511 S512	F341-V508 HydrophobicContact CB-CG2 4.46Å; F341-V508 HydrophobicContact CD1-CG2 4.21Å; F341-V508 HydrophobicContact CD2-CG2 3.56Å; F341-V508 HydrophobicContact CE1-CG2 4.38Å; F341-V508 HydrophobicContact CE2-CB 4.38Å; F341-V508 HydrophobicContact CE2-CG2 3.74Å; F341-V508 HydrophobicContact CG-CG2 3.81Å; F341-V508 HydrophobicContact CZ-CG2 4.16Å; T412-V508 WeakPolarHBondContact O-CG1 3.5Å; I415-V508 HydrophobicContact CB-CG1 4.34Å; I415-V508 HydrophobicContact CG2-CG1 4.26Å; V505-V508 PolarHBondContact O-N 3.04Å; V505-V508 VanDerWaalsContact O-N 3.11Å; V508-A511 PolarHBondContact O-N 3.09Å; V508-S512 WeakPolarHBondContact O-CB 3.34Å; V508-S512 PolarHBondContact O-N 3.28Å
509	I	92.9	Very high	92.1	Very high	89 Å²	89	41 Å²	41	46%	0.456	26%	0.259	S	S	.	.	H	α-helix	trans	-64.4	-43.5	174.8	-64.4	176.5	0	0	0	110.8	V505 V507 S512 A513	V505-I509 HydrophobicContact CG1-CD1 3.79Å; V505-I509 HydrophobicContact CG1-CG1 4.18Å; V505-I509 PolarHBondContact O-N 3.38Å; V505-I509 VanDerWaalsContact O-N 3.14Å; V507-I509 VanDerWaalsContact C-N 3.34Å; V507-I509 PolarHBondContact O-N 3.46Å; I509-S512 WeakPolarHBondContact O-CB 3.44Å; I509-S512 PolarHBondContact O-N 2.99Å; I509-A513 WeakPolarHBondContact O-CB 3.24Å; I509-A513 PolarHBondContact O-N 3.21Å
510	T	93.3	Very high	92.7	Very high	36 Å²	36	38.3 Å²	38.3	22%	0.221	25%	0.25	C	C	.	.	H	α-helix	trans	-63.4	-44.5	177.4	-58.9	0	0	0	0	110.6	L494 V506 V507 S512 A513 V514	L494-T510 HydrophobicContact CD1-CG2 4.42Å; V506-T510 VanDerWaalsContact O-CB 3.24Å; V506-T510 WeakPolarHBondContact O-CB 3.32Å; V506-T510 PolarHBondContact O-N 2.92Å; V506-T510 PolarHBondContact O-OG1 3.34Å; V507-T510 PolarHBondContact O-N 3.17Å; T510-S512 VanDerWaalsContact C-N 3.32Å; T510-S512 PolarHBondContact O-N 3.36Å; T510-A513 PolarHBondContact O-N 3.47Å; T510-V514 HydrophobicContact CG2-CG2 4.12Å; T510-V514 WeakPolarHBondContact O-CB 3.42Å; T510-V514 VanDerWaalsContact O-CG2 3.22Å; T510-V514 WeakPolarHBondContact O-CG2 3.48Å; T510-V514 PolarHBondContact O-N 2.96Å
511	A	94.6	Very high	93	Very high	0 Å²	0	35.4 Å²	35.4	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-57.1	-45.5	175.4	0	0	0	0	0	111.8	A330 S333 N334 F408 V507 V508 A515	A330-A511 WeakPolarHBondContact O-CB 3.49Å; S333-A511 WeakPolarHBondContact OG-CA 3.07Å; S333-A511 WeakPolarHBondContact OG-CB 3.29Å; N334-A511 HydrophobicContact CB-CB 3.81Å; F408-A511 HydrophobicContact CE1-CB 4.41Å; V507-A511 WeakPolarHBondContact O-CB 3.37Å; V507-A511 PolarHBondContact O-N 2.99Å; V508-A511 PolarHBondContact O-N 3.09Å; A511-A515 VanDerWaalsContact O-CB 3.24Å; A511-A515 WeakPolarHBondContact O-CB 3.45Å; A511-A515 PolarHBondContact O-N 3.4Å
512	S	96.3	Very high	93.2	Very high	14 Å²	14	33 Å²	33	10%	0.098	21%	0.209	C	C	.	.	H	α-helix	trans	-60.6	-49.7	176	179.3	0	0	0	0	111.8	G409 T412 G413 V508 I509 T510 A515 L516	G409-S512 WeakPolarHBondContact O-CB 3.35Å; G409-S512 PolarHBondContact O-OG 3.37Å; T412-S512 VanDerWaalsContact OG1-CA 3.25Å; T412-S512 WeakPolarHBondContact OG1-CA 3.04Å; T412-S512 WeakPolarHBondContact OG1-CB 3.2Å; G413-S512 WeakPolarHBondContact CA-OG 3.43Å; G413-S512 PolarHBondContact N-OG 2.7Å; V508-S512 WeakPolarHBondContact O-CB 3.34Å; V508-S512 PolarHBondContact O-N 3.28Å; I509-S512 WeakPolarHBondContact O-CB 3.44Å; I509-S512 PolarHBondContact O-N 2.99Å; T510-S512 VanDerWaalsContact C-N 3.32Å; T510-S512 PolarHBondContact O-N 3.36Å; S512-A515 PolarHBondContact O-N 3.22Å; S512-L516 WeakPolarHBondContact O-CG 3.27Å; S512-L516 PolarHBondContact O-N 3.11Å
513	A	96.3	Very high	93.6	Very high	45 Å²	45	31.6 Å²	31.6	37%	0.372	19%	0.191	S	C	.	.	H	α-helix	trans	-61.7	-47.9	179.9	0	0	0	0	0	112	I509 T510 A515 L516 I517	I509-A513 WeakPolarHBondContact O-CB 3.24Å; I509-A513 PolarHBondContact O-N 3.21Å; T510-A513 PolarHBondContact O-N 3.47Å; A513-A515 VanDerWaalsContact C-N 3.29Å; A513-A515 PolarHBondContact O-N 3.41Å; A513-L516 PolarHBondContact O-N 3.45Å; A513-I517 VanDerWaalsContact O-CG1 3.27Å; A513-I517 WeakPolarHBondContact O-CG1 3.32Å; A513-I517 PolarHBondContact O-N 3.25Å
514	V	96.4	Very high	93.9	Very high	32 Å²	32	35.4 Å²	35.4	19%	0.194	21%	0.208	C	C	.	.	H	α-helix	trans	-62.1	-38.8	178.1	177.6	0	0	0	0	110.6	I326 T329 A330 T510 I517 G518	I326-V514 HydrophobicContact CG2-CG1 3.76Å; I326-V514 VanDerWaalsContact CG2-O 3.3Å; I326-V514 WeakPolarHBondContact CG2-O 3.33Å; I326-V514 WeakPolarHBondContact O-CG1 3.21Å; T329-V514 HydrophobicContact CG2-CG1 4.34Å; A330-V514 HydrophobicContact CB-CB 4.03Å; A330-V514 HydrophobicContact CB-CG1 3.83Å; T510-V514 HydrophobicContact CG2-CG2 4.12Å; T510-V514 WeakPolarHBondContact O-CB 3.42Å; T510-V514 VanDerWaalsContact O-CG2 3.22Å; T510-V514 WeakPolarHBondContact O-CG2 3.48Å; T510-V514 PolarHBondContact O-N 2.96Å; V514-I517 PolarHBondContact O-N 2.75Å; V514-G518 PolarHBondContact O-N 3.15Å
515	A	96.9	Very high	94.2	Very high	0 Å²	0	39.5 Å²	39.5	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-67.1	-41.6	176.3	0	0	0	0	0	113.2	A330 Y405 F408 M434 A511 S512 A513 G518 C519	A330-A515 HydrophobicContact CB-CB 3.94Å; Y405-A515 HydrophobicContact CD1-CB 4.49Å; Y405-A515 VanDerWaalsContact CD1-O 3.26Å; Y405-A515 WeakPolarHBondContact CD1-O 3.4Å; F408-A515 HydrophobicContact CD1-CB 3.59Å; F408-A515 HydrophobicContact CE1-CB 4.23Å; M434-A515 HydrophobicContact CE-CB 4.34Å; A511-A515 VanDerWaalsContact O-CB 3.24Å; A511-A515 WeakPolarHBondContact O-CB 3.45Å; A511-A515 PolarHBondContact O-N 3.4Å; S512-A515 PolarHBondContact O-N 3.22Å; A513-A515 VanDerWaalsContact C-N 3.29Å; A513-A515 PolarHBondContact O-N 3.41Å; A515-G518 CarbonylContact O-C 3.53Å; A515-G518 WeakPolarHBondContact O-CA 3.34Å; A515-G518 PolarHBondContact O-N 2.87Å; A515-C519 WeakPolarHBondContact O-CB 3.34Å; A515-C519 PolarHBondContact O-N 2.98Å
516	L	97	Very high	94	Very high	62 Å²	62	38.2 Å²	38.2	33%	0.325	22%	0.218	S	C	.	.	H	α-helix	trans	-67.4	-37	176.3	-68.1	174	0	0	0	111.6	L406 S512 A513 G518 C519 C520	L406-L516 HydrophobicContact CD1-CD2 4.31Å; S512-L516 WeakPolarHBondContact O-CG 3.27Å; S512-L516 PolarHBondContact O-N 3.11Å; A513-L516 PolarHBondContact O-N 3.45Å; L516-G518 VanDerWaalsContact C-N 3.33Å; L516-C519 VanDerWaalsContact O-CB 3.24Å; L516-C519 WeakPolarHBondContact O-CB 3.5Å; L516-C519 PolarHBondContact O-N 3.47Å; L516-C520 PolarHBondContact O-N 3.36Å; L516-C520 PolarHBondContact O-SG 3.32Å
517	I	96.6	Very high	93.8	Very high	105 Å²	105	42 Å²	42	54%	0.538	23%	0.229	S	C	.	.	H	α-helix	trans	-61.1	-45.2	170	-68.1	165.1	0	0	0	110.1	A513 V514 C519 C520 F521	A513-I517 VanDerWaalsContact O-CG1 3.27Å; A513-I517 WeakPolarHBondContact O-CG1 3.32Å; A513-I517 PolarHBondContact O-N 3.25Å; V514-I517 PolarHBondContact O-N 2.75Å; I517-C519 VanDerWaalsContact C-N 3.3Å; I517-C519 PolarHBondContact O-N 3.02Å; I517-C520 PolarHBondContact O-N 3.37Å; I517-F521 WeakPolarHBondContact O-CB 3.32Å; I517-F521 PolarHBondContact O-N 2.94Å
518	G	95.8	Very high	93.4	Very high	0 Å²	0	47.7 Å²	47.7	0%	0	25%	0.251	C	S	.	.	H	α-helix	trans	-59.4	-39.6	174.6	0	0	0	0	0	112.9	V514 A515 L516 F521 V522	V514-G518 PolarHBondContact O-N 3.15Å; A515-G518 CarbonylContact O-C 3.53Å; A515-G518 WeakPolarHBondContact O-CA 3.34Å; A515-G518 PolarHBondContact O-N 2.87Å; L516-G518 VanDerWaalsContact C-N 3.33Å; G518-F521 PolarHBondContact O-N 3.05Å; G518-V522 WeakPolarHBondContact O-CG2 3.35Å; G518-V522 PolarHBondContact O-N 2.98Å
519	C	95.6	Very high	92.7	Very high	5 Å²	5	48.1 Å²	48.1	3%	0.034	25%	0.254	C	S	.	.	H	α-helix	trans	-57.6	-52.2	174.6	-170	0	0	0	0	111.4	F402 A515 L516 I517 F521 V522 A523	F402-C519 WeakPolarHBondContact CD2-SG 3.47Å; F402-C519 WeakPolarHBondContact CE2-SG 3.4Å; A515-C519 WeakPolarHBondContact O-CB 3.34Å; A515-C519 PolarHBondContact O-N 2.98Å; L516-C519 VanDerWaalsContact O-CB 3.24Å; L516-C519 WeakPolarHBondContact O-CB 3.5Å; L516-C519 PolarHBondContact O-N 3.47Å; I517-C519 VanDerWaalsContact C-N 3.3Å; I517-C519 PolarHBondContact O-N 3.02Å; C519-F521 VanDerWaalsContact C-N 3.33Å; C519-F521 PolarHBondContact O-N 3.36Å; C519-V522 PolarHBondContact O-N 2.68Å; C519-A523 PolarHBondContact O-N 2.94Å
520	C	95.9	Very high	91.2	Very high	78 Å²	78	53.2 Å²	53.2	53%	0.527	28%	0.282	S	S	.	.	H	α-helix	trans	-61.5	-41.7	175.6	-65.8	0	0	0	0	111.8	L516 I517 A523 L524	L516-C520 PolarHBondContact O-N 3.36Å; L516-C520 PolarHBondContact O-SG 3.32Å; I517-C520 PolarHBondContact O-N 3.37Å; C520-A523 PolarHBondContact O-N 3.33Å; C520-L524 VanDerWaalsContact O-CG 3.3Å; C520-L524 WeakPolarHBondContact O-CG 3.33Å; C520-L524 PolarHBondContact O-N 2.86Å
521	F	95.5	Very high	91.1	Very high	35 Å²	35	54.1 Å²	54.1	15%	0.154	29%	0.285	C	S	.	.	H	α-helix	trans	-62.8	-44.7	179.6	-170	-81.9	0	0	0	111.9	Y319 I322 I326 I517 G518 C519 A523 L524 F525	Y319-F521 AromaticContact CD1-CZ 4Å; Y319-F521 HydrophobicContact CD1-CZ 4Å; Y319-F521 WeakPolarHBondContact O-CE1 3.32Å; I322-F521 HydrophobicContact CB-CE1 4.17Å; I322-F521 HydrophobicContact CB-CZ 3.88Å; I322-F521 HydrophobicContact CD1-CZ 4.42Å; I322-F521 HydrophobicContact CG2-CE1 4Å; I322-F521 HydrophobicContact CG2-CE2 3.84Å; I322-F521 HydrophobicContact CG2-CZ 3.51Å; I326-F521 HydrophobicContact CD1-CB 4.48Å; I326-F521 HydrophobicContact CD1-CD2 4.36Å; I326-F521 HydrophobicContact CD1-CG 4.25Å; I517-F521 WeakPolarHBondContact O-CB 3.32Å; I517-F521 PolarHBondContact O-N 2.94Å; G518-F521 PolarHBondContact O-N 3.05Å; C519-F521 VanDerWaalsContact C-N 3.33Å; C519-F521 PolarHBondContact O-N 3.36Å; F521-A523 PolarHBondContact O-N 2.93Å; F521-L524 PolarHBondContact O-N 3.39Å; F521-F525 HydrophobicContact CD1-CB 4.29Å; F521-F525 HydrophobicContact CD1-CD2 4.18Å; F521-F525 AromaticContact CD2-CD2 3.53Å; F521-F525 HydrophobicContact CD2-CD2 3.53Å; F521-F525 AromaticContact CD2-CE2 3.89Å; F521-F525 HydrophobicContact CD2-CE2 3.89Å; F521-F525 HydrophobicContact CE1-CB 3.91Å; F521-F525 HydrophobicContact CE1-CD2 4.19Å; F521-F525 HydrophobicContact CE1-CG 4.37Å; F521-F525 AromaticContact CE2-CD2 3.55Å; F521-F525 HydrophobicContact CE2-CD2 3.55Å; F521-F525 AromaticContact CE2-CE2 3.95Å; F521-F525 HydrophobicContact CE2-CE2 3.95Å; F521-F525 HydrophobicContact CE2-CG 4.21Å; F521-F525 AromaticContact CG-CD2 3.87Å; F521-F525 HydrophobicContact CG-CD2 3.87Å; F521-F525 HydrophobicContact CZ-CB 4.09Å; F521-F525 AromaticContact CZ-CD2 3.89Å; F521-F525 HydrophobicContact CZ-CD2 3.89Å; F521-F525 HydrophobicContact CZ-CG 4.13Å; F521-F525 PolarHBondContact O-N 3.49Å
522	V	93.9	Very high	90.9	Very high	0 Å²	0	56.9 Å²	56.9	0%	0	30%	0.3	C	S	.	.	H	α-helix	trans	-61.3	-44.9	175.8	169	0	0	0	0	110.9	K398 Y401 F402 Y405 G518 C519 L524 V526	K398-V522 WeakPolarHBondContact CE-O 3.4Å; K398-V522 HydrophobicContact CG-CG1 4.48Å; Y401-V522 HydrophobicContact CD1-CG1 3.95Å; Y401-V522 HydrophobicContact CD1-CG2 3.68Å; Y401-V522 HydrophobicContact CE1-CG2 3.82Å; Y401-V522 HydrophobicContact CG-CG1 4.1Å; Y401-V522 HydrophobicContact CG-CG2 4.09Å; F402-V522 HydrophobicContact CB-CG1 4.16Å; Y405-V522 HydrophobicContact CD2-CG2 3.78Å; Y405-V522 HydrophobicContact CE2-CG2 3.5Å; G518-V522 WeakPolarHBondContact O-CG2 3.35Å; G518-V522 PolarHBondContact O-N 2.98Å; C519-V522 PolarHBondContact O-N 2.68Å; V522-L524 VanDerWaalsContact C-N 3.3Å; V522-L524 PolarHBondContact O-N 3.44Å; V522-V526 HydrophobicContact CB-CG2 4.29Å; V522-V526 HydrophobicContact CG1-CB 4.32Å; V522-V526 HydrophobicContact CG1-CG2 4.21Å; V522-V526 HydrophobicContact CG2-CG2 4.17Å; V522-V526 WeakPolarHBondContact O-CB 3.22Å; V522-V526 PolarHBondContact O-N 2.74Å
523	A	93.2	Very high	90.6	Very high	43 Å²	43	59.3 Å²	59.3	36%	0.355	31%	0.311	S	S	.	.	H	α-helix	trans	-58.7	-41.5	178.3	0	0	0	0	0	112.4	K398 F402 C519 C520 F521	K398-A523 VanDerWaalsContact CE-O 3.27Å; K398-A523 WeakPolarHBondContact CE-O 3.43Å; K398-A523 PolarHBondContact NZ-O 3.48Å; F402-A523 HydrophobicContact CD2-CB 3.92Å; F402-A523 HydrophobicContact CE2-CB 4.01Å; C519-A523 PolarHBondContact O-N 2.94Å; C520-A523 PolarHBondContact O-N 3.33Å; F521-A523 PolarHBondContact O-N 2.93Å
524	L	93	Very high	90.3	Very high	132 Å²	132	60.1 Å²	60.1	69%	0.691	31%	0.308	S	S	*	.	H	α-helix	trans	-84.9	-42	-173.7	-65.9	173.8	0	0	0	114	C520 F521 V522	C520-L524 VanDerWaalsContact O-CG 3.3Å; C520-L524 WeakPolarHBondContact O-CG 3.33Å; C520-L524 PolarHBondContact O-N 2.86Å; F521-L524 PolarHBondContact O-N 3.39Å; V522-L524 VanDerWaalsContact C-N 3.3Å; V522-L524 PolarHBondContact O-N 3.44Å
525	F	92.4	Very high	89.9	Confident	90 Å²	90	61.9 Å²	61.9	40%	0.395	32%	0.315	S	S	.	.	H	α-helix	trans	-112.7	-23.4	-164.6	-63.1	-73.3	0	0	0	115.3	Y319 F521 R527	Y319-F525 HydrophobicContact CD1-CB 4.05Å; Y319-F525 HydrophobicContact CD1-CD1 4.27Å; Y319-F525 HydrophobicContact CD1-CG 4.31Å; Y319-F525 HydrophobicContact CD2-CB 4.18Å; Y319-F525 HydrophobicContact CE1-CD1 4.01Å; Y319-F525 HydrophobicContact CE1-CG 4.49Å; Y319-F525 HydrophobicContact CE2-CD1 4.44Å; Y319-F525 HydrophobicContact CG-CB 3.83Å; F521-F525 HydrophobicContact CD1-CB 4.29Å; F521-F525 HydrophobicContact CD1-CD2 4.18Å; F521-F525 AromaticContact CD2-CD2 3.53Å; F521-F525 HydrophobicContact CD2-CD2 3.53Å; F521-F525 AromaticContact CD2-CE2 3.89Å; F521-F525 HydrophobicContact CD2-CE2 3.89Å; F521-F525 HydrophobicContact CE1-CB 3.91Å; F521-F525 HydrophobicContact CE1-CD2 4.19Å; F521-F525 HydrophobicContact CE1-CG 4.37Å; F521-F525 AromaticContact CE2-CD2 3.55Å; F521-F525 HydrophobicContact CE2-CD2 3.55Å; F521-F525 AromaticContact CE2-CE2 3.95Å; F521-F525 HydrophobicContact CE2-CE2 3.95Å; F521-F525 HydrophobicContact CE2-CG 4.21Å; F521-F525 AromaticContact CG-CD2 3.87Å; F521-F525 HydrophobicContact CG-CD2 3.87Å; F521-F525 HydrophobicContact CZ-CB 4.09Å; F521-F525 AromaticContact CZ-CD2 3.89Å; F521-F525 HydrophobicContact CZ-CD2 3.89Å; F521-F525 HydrophobicContact CZ-CG 4.13Å; F521-F525 PolarHBondContact O-N 3.49Å; F525-R527 PolarHBondContact O-N 3.03Å
526	V	87.4	Confident	89.4	Confident	3 Å²	3	66 Å²	66	2%	0.018	34%	0.336	C	S	.	.	S	Bend	trans	-73.8	125	177.2	176	0	0	0	0	108.7	K398 Y401 L445 V522	K398-V526 VanDerWaalsContact CD-O 3.31Å; K398-V526 WeakPolarHBondContact CD-O 3.21Å; K398-V526 WeakPolarHBondContact CE-O 3.48Å; K398-V526 HydrophobicContact CG-CG1 4.38Å; K398-V526 PolarHBondContact NZ-O 3.16Å; Y401-V526 HydrophobicContact CD1-CG2 4.5Å; L445-V526 HydrophobicContact CD1-CG1 3.92Å; V522-V526 HydrophobicContact CB-CG2 4.29Å; V522-V526 HydrophobicContact CG1-CB 4.32Å; V522-V526 HydrophobicContact CG1-CG2 4.21Å; V522-V526 HydrophobicContact CG2-CG2 4.17Å; V522-V526 WeakPolarHBondContact O-CB 3.22Å; V522-V526 PolarHBondContact O-N 2.74Å
527	R	85.6	Confident	88.9	Confident	108 Å²	108	66.3 Å²	66.3	41%	0.408	34%	0.337	S	S	.	.	P	Polyproline II helix	trans	-65.3	134.3	179.9	-173.5	-177.4	174.8	177.4	0.2	109.3	Y449 E452 F525	Y449-R527 HydrophobicContact CE1-CB 4.04Å; Y449-R527 PolarHBondContact OH-N 3.13Å; Y449-R527 PolarHBondContact OH-O 3.38Å; E452-R527 IonicContact OE2-CZ 2.93Å; E452-R527 VanDerWaalsContact OE2-CZ 3.27Å; E452-R527 IonicContact OE2-NE 3.16Å; E452-R527 IonicContact OE2-NH1 2.66Å; E452-R527 PolarHBondContact OE2-NH1 3.35Å; E452-R527 IonicContact OE2-NH2 3.41Å; E452-R527 PolarHBondContact OE2-NH2 2.94Å; F525-R527 PolarHBondContact O-N 3.03Å
528	Y	81.3	Confident	88.3	Confident	122 Å²	122	63.3 Å²	63.3	48%	0.478	32%	0.321	S	S	.	.	P	Polyproline II helix	trans	-72.9	140.6	170.7	-166.4	-88.9	0	0	0	109.1	K398 D530	K398-Y528 HydrophobicContact CB-CD2 4.17Å; K398-Y528 HydrophobicContact CD-CD2 4.15Å; Y528-D530 WeakPolarHBondContact CE1-OD1 3.1Å
529	V	77.4	Confident	87.6	Confident	11 Å²	11	68.6 Å²	68.6	7%	0.067	35%	0.348	C	S	.	.			trans	-133.6	121.6	-175.3	-177.9	0	0	0	0	106.2	L445 E448 Y449	L445-V529 HydrophobicContact CD2-CG2 4.13Å; E448-V529 HydrophobicContact CB-CG1 3.83Å; E448-V529 HydrophobicContact CG-CB 4.44Å; E448-V529 HydrophobicContact CG-CG1 3.05Å; Y449-V529 HydrophobicContact CD1-CG2 3.92Å; Y449-V529 HydrophobicContact CE1-CG2 3.38Å
530	D	60.7	Low	86.9	Confident	196 Å²	196	74.4 Å²	74.4	100%	1.048	38%	0.376	S	S	*	.			trans	-80.8	0	-173.4	-73.5	-54.4	0	0	0	113.5	Y528	Y528-D530 WeakPolarHBondContact CE1-OD1 3.1Å

Retrieved 530 of 530 residues in 223.5 ms (Link to these results)

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