SERP1_HUMAN Loading...

Stress-associated endoplasmic reticulum protein 1

Interacts with target proteins during their translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation during ER stress. May facilitate glycosylation of target proteins after termination of ER stress. May modulate the use of N-glycosylation sites on target proteins.

AlphaFold DB , UniProt , Accession Q9Y6X1, Species HUMAN (Homo sapiens, Human), Gene SERP1, Length 66 aa.

						>SERP1_HUMAN|Q9Y6X1|SERP1
MVAKQRIRMANEKHSKNITQRGNVAKTSRNAPEEKASVGPWLLALFIFVVCGSAIFQIIQSIRMGM
					

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	61.5	Low	83.4	Confident	160 Å²	160	116.5 Å²	116.5	79%	0.788	59%	0.586	S	S	*	*				0	126.2	0	-78.3	-163.8	-93.9	0	0	109	R6	M1-R6 HydrophobicContact CB-CG 4.39Å
2	V	79.3	Confident	83.6	Confident	96 Å²	96	115.3 Å²	115.3	58%	0.582	58%	0.576	S	S	*	*			trans	-63.3	140.6	-179.4	180	0	0	0	0	109.1	K4 Q5 R6	V2-K4 HydrophobicContact CG1-CB 4.14Å; V2-K4 PolarHBondContact O-N 3.26Å; V2-K4 VanDerWaalsContact O-N 3.09Å; V2-Q5 HydrophobicContact CB-CG 4.27Å; V2-Q5 WeakPolarHBondContact O-CA 3.24Å; V2-Q5 WeakPolarHBondContact O-CB 3.5Å; V2-Q5 PolarHBondContact O-N 3.06Å; V2-R6 PolarHBondContact O-N 3.32Å
3	A	82.4	Confident	83.7	Confident	71 Å²	71	118.3 Å²	118.3	59%	0.587	58%	0.584	S	S	*	*	H	α-helix	trans	-49.8	-40.5	-179.1	0	0	0	0	0	112.5	Q5 R6 I7	A3-Q5 VanDerWaalsContact C-N 3.31Å; A3-Q5 PolarHBondContact O-N 3.38Å; A3-R6 PolarHBondContact O-N 2.98Å; A3-R6 VanDerWaalsContact O-N 3.16Å; A3-I7 WeakPolarHBondContact O-CG1 3.3Å; A3-I7 PolarHBondContact O-N 3.01Å; A3-I7 VanDerWaalsContact O-N 3.08Å
4	K	86.1	Confident	83.6	Confident	149 Å²	149	119.1 Å²	119.1	65%	0.648	59%	0.585	S	S	*	*	H	α-helix	trans	-56.1	-38.8	174	-167.7	177.8	-175.4	-174.3	0	113.5	V2 R8	V2-K4 HydrophobicContact CG1-CB 4.14Å; V2-K4 PolarHBondContact O-N 3.26Å; V2-K4 VanDerWaalsContact O-N 3.09Å; K4-R8 WeakPolarHBondContact O-CG 3.39Å; K4-R8 PolarHBondContact O-N 3.43Å; K4-R8 VanDerWaalsContact O-N 3.08Å
5	Q	85.8	Confident	83.5	Confident	106 Å²	106	114.7 Å²	114.7	50%	0.495	57%	0.571	S	S	.	*	H	α-helix	trans	-68.2	-40.9	178	-68.8	174.8	-46.1	0	0	111.5	V2 A3 I7 R8 M9	V2-Q5 HydrophobicContact CB-CG 4.27Å; V2-Q5 WeakPolarHBondContact O-CA 3.24Å; V2-Q5 WeakPolarHBondContact O-CB 3.5Å; V2-Q5 PolarHBondContact O-N 3.06Å; A3-Q5 VanDerWaalsContact C-N 3.31Å; A3-Q5 PolarHBondContact O-N 3.38Å; Q5-I7 PolarHBondContact O-N 2.93Å; Q5-R8 PolarHBondContact O-N 2.85Å; Q5-M9 PolarHBondContact O-N 3.34Å
6	R	87.3	Confident	83.4	Confident	164 Å²	164	118.1 Å²	118.1	62%	0.619	58%	0.581	S	S	*	*	H	α-helix	trans	-62.4	-43.2	176.6	-68	-178.2	172.8	175.7	-1.6	111.6	M1 V2 A3 M9 A10	M1-R6 HydrophobicContact CB-CG 4.39Å; V2-R6 PolarHBondContact O-N 3.32Å; A3-R6 PolarHBondContact O-N 2.98Å; A3-R6 VanDerWaalsContact O-N 3.16Å; R6-M9 PolarHBondContact O-N 3.34Å; R6-A10 WeakPolarHBondContact O-CB 3.29Å; R6-A10 PolarHBondContact O-N 3.32Å
7	I	88.7	Confident	83.1	Confident	102 Å²	102	118.1 Å²	118.1	52%	0.523	58%	0.584	S	S	.	*	H	α-helix	trans	-63.7	-43.4	177.9	-63.3	167	0	0	0	110.9	A3 Q5 M9 A10 N11	A3-I7 WeakPolarHBondContact O-CG1 3.3Å; A3-I7 PolarHBondContact O-N 3.01Å; A3-I7 VanDerWaalsContact O-N 3.08Å; Q5-I7 PolarHBondContact O-N 2.93Å; I7-M9 PolarHBondContact O-N 2.83Å; I7-A10 PolarHBondContact O-N 3.45Å; I7-N11 PolarHBondContact O-N 3.31Å
8	R	87.3	Confident	82.6	Confident	150 Å²	150	115.2 Å²	115.2	57%	0.566	57%	0.57	S	S	*	*	H	α-helix	trans	-59.6	-47.2	176.1	-73.2	175.9	69.4	154.2	6.1	111.9	K4 Q5 A10 N11 E12	K4-R8 WeakPolarHBondContact O-CG 3.39Å; K4-R8 PolarHBondContact O-N 3.43Å; K4-R8 VanDerWaalsContact O-N 3.08Å; Q5-R8 PolarHBondContact O-N 2.85Å; R8-A10 VanDerWaalsContact C-N 3.31Å; R8-A10 PolarHBondContact O-N 2.85Å; R8-N11 PolarHBondContact O-N 3.11Å; R8-E12 WeakPolarHBondContact O-CB 3.26Å; R8-E12 VanDerWaalsContact O-CG 3.32Å; R8-E12 WeakPolarHBondContact O-CG 3.3Å; R8-E12 PolarHBondContact O-N 2.91Å
9	M	86.1	Confident	82.4	Confident	120 Å²	120	115.9 Å²	115.9	59%	0.591	58%	0.582	S	S	*	*	H	α-helix	trans	-62.5	-37.9	178.5	-170	178.4	-70.7	0	0	112.2	Q5 R6 I7 K13	Q5-M9 PolarHBondContact O-N 3.34Å; R6-M9 PolarHBondContact O-N 3.34Å; I7-M9 PolarHBondContact O-N 2.83Å; M9-K13 WeakPolarHBondContact O-CB 3.26Å; M9-K13 PolarHBondContact O-N 2.94Å
10	A	85.7	Confident	81.7	Confident	57 Å²	57	116.5 Å²	116.5	47%	0.471	58%	0.583	S	S	.	*	H	α-helix	trans	-66	-44.5	174.8	0	0	0	0	0	112.1	R6 I7 R8 E12 K13 H14	R6-A10 WeakPolarHBondContact O-CB 3.29Å; R6-A10 PolarHBondContact O-N 3.32Å; I7-A10 PolarHBondContact O-N 3.45Å; R8-A10 VanDerWaalsContact C-N 3.31Å; R8-A10 PolarHBondContact O-N 2.85Å; A10-E12 VanDerWaalsContact C-N 3.35Å; A10-E12 PolarHBondContact O-N 3.41Å; A10-K13 PolarHBondContact O-N 3.46Å; A10-H14 PolarHBondContact O-N 3.08Å
11	N	87.1	Confident	81	Confident	107 Å²	107	118.9 Å²	118.9	57%	0.572	59%	0.585	S	S	*	*	H	α-helix	trans	-64.1	-40	176.4	-76.2	0.4	0	0	0	111.8	I7 R8 H14 S15	I7-N11 PolarHBondContact O-N 3.31Å; R8-N11 PolarHBondContact O-N 3.11Å; N11-H14 PolarHBondContact O-N 3.2Å; N11-S15 WeakPolarHBondContact O-CB 3.15Å; N11-S15 PolarHBondContact O-N 3.33Å
12	E	85.5	Confident	81.4	Confident	101 Å²	101	114.2 Å²	114.2	47%	0.472	58%	0.578	S	S	.	*	H	α-helix	trans	-64.3	-40.2	175.9	-74.7	169.4	-160.8	0	0	111.5	R8 A10 S15 K16	R8-E12 WeakPolarHBondContact O-CB 3.26Å; R8-E12 VanDerWaalsContact O-CG 3.32Å; R8-E12 WeakPolarHBondContact O-CG 3.3Å; R8-E12 PolarHBondContact O-N 2.91Å; A10-E12 VanDerWaalsContact C-N 3.35Å; A10-E12 PolarHBondContact O-N 3.41Å; E12-S15 PolarHBondContact O-N 2.84Å; E12-K16 VanDerWaalsContact O-CG 3.3Å; E12-K16 WeakPolarHBondContact O-CG 3.26Å; E12-K16 PolarHBondContact O-N 2.93Å
13	K	85.3	Confident	80.7	Confident	155 Å²	155	114.9 Å²	114.9	67%	0.674	58%	0.578	S	S	*	*	H	α-helix	trans	-64.4	-46.1	174.5	-172.6	177.3	-178.7	-179.9	0	111.7	M9 A10 K16	M9-K13 WeakPolarHBondContact O-CB 3.26Å; M9-K13 PolarHBondContact O-N 2.94Å; A10-K13 PolarHBondContact O-N 3.46Å; K13-K16 PolarHBondContact O-N 2.81Å
14	H	82.6	Confident	79.8	Confident	129 Å²	129	116.7 Å²	116.7	60%	0.597	58%	0.581	S	S	*	*	H	α-helix	trans	-64.1	-43.4	178.1	-169.1	73.3	0	0	0	111.1	A10 N11 K16 N17 I18	A10-H14 PolarHBondContact O-N 3.08Å; N11-H14 PolarHBondContact O-N 3.2Å; H14-K16 VanDerWaalsContact C-N 3.27Å; H14-K16 PolarHBondContact O-N 3Å; H14-N17 PolarHBondContact O-N 2.84Å; H14-N17 VanDerWaalsContact O-N 3.12Å; H14-I18 WeakPolarHBondContact O-CG1 3.39Å; H14-I18 PolarHBondContact O-N 3.37Å
15	S	82.6	Confident	78.7	Confident	54 Å²	54	113.8 Å²	113.8	38%	0.378	59%	0.585	S	S	.	*	H	α-helix	trans	-62.1	-31.5	-177.9	-167.9	0	0	0	0	113.2	N11 E12 R21	N11-S15 WeakPolarHBondContact O-CB 3.15Å; N11-S15 PolarHBondContact O-N 3.33Å; E12-S15 PolarHBondContact O-N 2.84Å; S15-R21 PolarHBondContact OG-NH2 3.31Å
16	K	81.6	Confident	77.6	Confident	168 Å²	168	116.4 Å²	116.4	73%	0.73	60%	0.595	S	S	*	*	H	α-helix	trans	-71.4	-26.9	177.3	-72.7	172.9	-175.6	-169.4	0	113.6	E12 K13 H14	E12-K16 VanDerWaalsContact O-CG 3.3Å; E12-K16 WeakPolarHBondContact O-CG 3.26Å; E12-K16 PolarHBondContact O-N 2.93Å; K13-K16 PolarHBondContact O-N 2.81Å; H14-K16 VanDerWaalsContact C-N 3.27Å; H14-K16 PolarHBondContact O-N 3Å
17	N	77.3	Confident	76.2	Confident	119 Å²	119	113.4 Å²	113.4	64%	0.636	60%	0.595	S	S	*	*	H	α-helix	trans	-87.9	-8.8	179.7	-70	-8	0	0	0	113.4	H14 T19	H14-N17 PolarHBondContact O-N 2.84Å; H14-N17 VanDerWaalsContact O-N 3.12Å; N17-T19 VanDerWaalsContact C-N 3.3Å; N17-T19 PolarHBondContact O-N 3.45Å
18	I	75	Confident	74.8	Confident	66 Å²	66	114.8 Å²	114.8	34%	0.338	61%	0.614	S	S	.	*			trans	-80.6	80.9	175	-49.9	-55.5	0	0	0	108.9	H14 Q20 R21	H14-I18 WeakPolarHBondContact O-CG1 3.39Å; H14-I18 PolarHBondContact O-N 3.37Å; I18-Q20 VanDerWaalsContact C-N 3.34Å; I18-R21 HydrophobicContact CG2-CB 3.73Å; I18-R21 HydrophobicContact CG2-CG 4.35Å
19	T	77.9	Confident	73.3	Confident	129 Å²	129	118.2 Å²	118.2	79%	0.791	63%	0.627	S	S	*	*	T	Hydrogen-bonded Turn	trans	-73.8	-26.7	177.5	53.6	0	0	0	0	112.8	N17	N17-T19 VanDerWaalsContact C-N 3.3Å; N17-T19 PolarHBondContact O-N 3.45Å
20	Q	69	Low	71.7	Confident	127 Å²	127	117.8 Å²	117.8	59%	0.593	63%	0.627	S	S	*	*	T	Hydrogen-bonded Turn	trans	-99.8	25.6	-175.4	-65.5	-96.8	71.6	0	0	112.3	I18 G22 N23	I18-Q20 VanDerWaalsContact C-N 3.34Å; Q20-G22 PolarHBondContact O-N 2.85Å; Q20-N23 HydrophobicContact CB-CB 4.2Å; Q20-N23 PolarHBondContact O-N 2.94Å
21	R	67.2	Low	70.2	Confident	166 Å²	166	117.9 Å²	117.9	63%	0.626	63%	0.628	S	S	*	*	T	Hydrogen-bonded Turn	trans	-64	111.6	178.9	-165.3	176.4	-65.8	-152.3	3.9	108.8	S15 I18	S15-R21 PolarHBondContact OG-NH2 3.31Å; I18-R21 HydrophobicContact CG2-CB 3.73Å; I18-R21 HydrophobicContact CG2-CG 4.35Å
22	G	68.9	Low	68.6	Low	62 Å²	62	117.8 Å²	117.8	64%	0.639	63%	0.633	S	S	*	*	T	Hydrogen-bonded Turn	trans	94.5	-3.2	-177.4	0	0	0	0	0	115	Q20 V24	Q20-G22 PolarHBondContact O-N 2.85Å; G22-V24 PolarHBondContact O-N 3.14Å
23	N	64.7	Low	67.1	Low	110 Å²	110	118.8 Å²	118.8	59%	0.588	64%	0.638	S	S	*	*			trans	-78.4	52.1	162.4	-166.2	60.9	0	0	0	110.2	Q20	Q20-N23 HydrophobicContact CB-CB 4.2Å; Q20-N23 PolarHBondContact O-N 2.94Å
24	V	65.2	Low	65.8	Low	109 Å²	109	120 Å²	120	66%	0.661	65%	0.646	S	S	*	*			trans	-82.2	122.7	160.8	64.2	0	0	0	0	105.1	G22 K26	G22-V24 PolarHBondContact O-N 3.14Å; V24-K26 PolarHBondContact O-N 2.89Å
25	A	62.7	Low	64.7	Low	88 Å²	88	122.2 Å²	122.2	73%	0.727	65%	0.654	S	S	*	*			trans	-48.5	116.3	171.4	0	0	0	0	0	106.8	T27	A25-T27 PolarHBondContact O-N 3.47Å
26	K	62.2	Low	63.8	Low	162 Å²	162	122.5 Å²	122.5	70%	0.704	66%	0.66	S	S	*	*			trans	-70.8	74.1	-170.5	-70.4	-175	-178.8	-177.5	0	109.4	V24	V24-K26 PolarHBondContact O-N 2.89Å
27	T	57.4	Low	63.2	Low	100 Å²	100	120.8 Å²	120.8	61%	0.613	67%	0.669	S	S	*	*			trans	59.3	151.3	-179.9	74.9	0	0	0	0	112.8	A25 R29	A25-T27 PolarHBondContact O-N 3.47Å; T27-R29 PolarHBondContact O-N 3.37Å; T27-R29 WeakPolarHBondContact OG1-CB 3.16Å
28	S	60.3	Low	63.1	Low	132 Å²	132	118.5 Å²	118.5	92%	0.923	66%	0.659	S	S	*	*	T	Hydrogen-bonded Turn	trans	-67	9.9	173.6	70.4	0	0	0	0	113.3
29	R	55.8	Low	63.6	Low	222 Å²	222	116.9 Å²	116.9	84%	0.838	66%	0.658	S	S	*	*	T	Hydrogen-bonded Turn	trans	-103.9	-11.6	-166.7	-138.9	175.7	-178.1	145.4	1.6	113.9	T27	T27-R29 PolarHBondContact O-N 3.37Å; T27-R29 WeakPolarHBondContact OG1-CB 3.16Å
30	N	51.2	Low	64.1	Low	110 Å²	110	116.2 Å²	116.2	59%	0.588	66%	0.656	S	S	*	*			trans	-103.9	61.2	175.2	-68.5	6	0	0	0	110.1	P32	N30-P32 WeakPolarHBondContact O-CD 3.37Å
31	A	54.6	Low	65.1	Low	59 Å²	59	119.6 Å²	119.6	49%	0.488	66%	0.664	S	S	.	*			trans	-89.7	81.5	150.9	0	0	0	0	0	107.4	E33 E34	A31-E33 PolarHBondContact O-N 3.42Å; A31-E34 PolarHBondContact O-N 2.92Å
32	P	53.3	Low	66.3	Low	106 Å²	106	116.6 Å²	116.6	69%	0.688	66%	0.66	S	S	*	*	T	Hydrogen-bonded Turn	trans	-70.4	7.5	173.5	32.9	-37.3	0	0	0	112.9	N30	N30-P32 WeakPolarHBondContact O-CD 3.37Å
33	E	55.5	Low	67.3	Low	121 Å²	121	117.3 Å²	117.3	57%	0.565	65%	0.649	S	S	*	*	T	Hydrogen-bonded Turn	trans	-106.5	44.4	170.3	31.6	-82.1	150.9	0	0	111.7	A31 K35	A31-E33 PolarHBondContact O-N 3.42Å; E33-K35 HydrophobicContact CB-CD 4.35Å; E33-K35 HydrophobicContact CB-CG 4.1Å; E33-K35 PolarHBondContact O-N 2.89Å
34	E	57.1	Low	68.6	Low	180 Å²	180	114.8 Å²	114.8	84%	0.841	64%	0.643	S	S	*	*			trans	-58.9	38.4	145.9	-68.3	-177.2	146.4	0	0	111.7	A31 A36	A31-E34 PolarHBondContact O-N 2.92Å; E34-A36 VanDerWaalsContact C-N 3.29Å; E34-A36 PolarHBondContact O-N 3.35Å
35	K	59.4	Low	70	Confident	176 Å²	176	113.3 Å²	113.3	77%	0.765	63%	0.631	S	S	*	*	S	Bend	trans	-44.4	109.6	140.9	-59.2	-176.2	-176.9	-168.5	0	103.5	E33 S37	E33-K35 HydrophobicContact CB-CD 4.35Å; E33-K35 HydrophobicContact CB-CG 4.1Å; E33-K35 PolarHBondContact O-N 2.89Å; K35-S37 PolarHBondContact O-N 2.83Å
36	A	63	Low	71.6	Confident	61 Å²	61	115.5 Å²	115.5	50%	0.504	62%	0.624	S	S	.	*			trans	-26.3	128.6	-166.1	0	0	0	0	0	112	E34 V38	E34-A36 VanDerWaalsContact C-N 3.29Å; E34-A36 PolarHBondContact O-N 3.35Å; A36-V38 HydrophobicContact CB-CG2 3.79Å; A36-V38 CarbonylContact O-C 3.23Å; A36-V38 VanDerWaalsContact O-C 3.23Å; A36-V38 PolarHBondContact O-N 3.27Å
37	S	68.9	Low	73.1	Confident	132 Å²	132	113 Å²	113	92%	0.923	62%	0.617	S	S	*	*	S	Bend	trans	-50.6	-15.8	178.8	-177.8	0	0	0	0	113.1	K35	K35-S37 PolarHBondContact O-N 2.83Å
38	V	76.7	Confident	74.9	Confident	70 Å²	70	114.7 Å²	114.7	42%	0.424	62%	0.617	S	S	.	*	S	Bend	trans	-92.6	113.8	168.4	-67.1	0	0	0	0	111.5	A36 L43	A36-V38 HydrophobicContact CB-CG2 3.79Å; A36-V38 CarbonylContact O-C 3.23Å; A36-V38 VanDerWaalsContact O-C 3.23Å; A36-V38 PolarHBondContact O-N 3.27Å; V38-L43 HydrophobicContact CB-CD2 4.29Å; V38-L43 HydrophobicContact CB-CG 4.26Å; V38-L43 HydrophobicContact CG2-CD1 4.17Å; V38-L43 HydrophobicContact CG2-CD2 3.72Å; V38-L43 HydrophobicContact CG2-CG 3.92Å
39	G	84	Confident	76.5	Confident	32 Å²	32	112.8 Å²	112.8	33%	0.33	60%	0.599	S	S	.	*			trans	-64.8	156.1	175.2	0	0	0	0	0	112.7	W41 L42 L43	G39-W41 PolarHBondContact O-N 3.35Å; G39-W41 VanDerWaalsContact O-N 3.08Å; G39-L42 PolarHBondContact O-N 2.93Å; G39-L43 PolarHBondContact O-N 3.44Å; G39-L43 VanDerWaalsContact O-N 3.1Å
40	P	88.2	Confident	78.3	Confident	116 Å²	116	106 Å²	106	75%	0.753	58%	0.582	S	S	*	*	H	α-helix	trans	-53	-34.1	179.2	-27.1	34.5	0	0	0	113.9	L43 A44	P40-L43 PolarHBondContact O-N 3.46Å; P40-A44 WeakPolarHBondContact O-CB 3.07Å; P40-A44 PolarHBondContact O-N 2.91Å
41	W	91.7	Very high	80.4	Confident	197 Å²	197	104 Å²	104	75%	0.746	58%	0.576	S	S	*	*	H	α-helix	trans	-65	-44.1	176.7	-172.2	-102.1	0	0	0	112.8	G39 A44 L45	G39-W41 PolarHBondContact O-N 3.35Å; G39-W41 VanDerWaalsContact O-N 3.08Å; W41-A44 PolarHBondContact O-N 3.35Å; W41-L45 WeakPolarHBondContact O-CB 3.14Å; W41-L45 WeakPolarHBondContact O-CG 3.44Å; W41-L45 PolarHBondContact O-N 2.72Å
42	L	91.2	Very high	82.2	Confident	103 Å²	103	101.7 Å²	101.7	54%	0.539	56%	0.558	S	S	.	*	H	α-helix	trans	-66.3	-39.7	177	-72.1	173.6	0	0	0	111.3	G39 L45 F46	G39-L42 PolarHBondContact O-N 2.93Å; L42-L45 PolarHBondContact O-N 3.1Å; L42-F46 VanDerWaalsContact O-CB 3.25Å; L42-F46 WeakPolarHBondContact O-CB 3.08Å; L42-F46 PolarHBondContact O-N 3.46Å
43	L	90.7	Very high	84	Confident	78 Å²	78	99.2 Å²	99.2	41%	0.408	54%	0.543	S	S	.	.	H	α-helix	trans	-61.9	-44.9	174	-72.2	173.6	0	0	0	111.8	V38 G39 P40 F46 I47	V38-L43 HydrophobicContact CB-CD2 4.29Å; V38-L43 HydrophobicContact CB-CG 4.26Å; V38-L43 HydrophobicContact CG2-CD1 4.17Å; V38-L43 HydrophobicContact CG2-CD2 3.72Å; V38-L43 HydrophobicContact CG2-CG 3.92Å; G39-L43 PolarHBondContact O-N 3.44Å; G39-L43 VanDerWaalsContact O-N 3.1Å; P40-L43 PolarHBondContact O-N 3.46Å; L43-F46 PolarHBondContact O-N 2.99Å; L43-I47 WeakPolarHBondContact O-CG1 3.33Å; L43-I47 PolarHBondContact O-N 3.08Å
44	A	92.7	Very high	85.8	Confident	57 Å²	57	95.7 Å²	95.7	47%	0.471	53%	0.534	S	S	.	.	H	α-helix	trans	-62.5	-45.6	176.9	0	0	0	0	0	111.8	P40 W41 F46 I47 F48	P40-A44 WeakPolarHBondContact O-CB 3.07Å; P40-A44 PolarHBondContact O-N 2.91Å; W41-A44 PolarHBondContact O-N 3.35Å; A44-F46 VanDerWaalsContact C-N 3.32Å; A44-F46 PolarHBondContact O-N 2.93Å; A44-I47 PolarHBondContact O-N 3.46Å; A44-F48 VanDerWaalsContact O-CB 3.29Å; A44-F48 WeakPolarHBondContact O-CB 3.29Å; A44-F48 PolarHBondContact O-N 3.06Å
45	L	94.3	Very high	87.5	Confident	77 Å²	77	91.3 Å²	91.3	40%	0.403	52%	0.516	S	S	.	.	H	α-helix	trans	-59.7	-43.5	173.9	-75	177.6	0	0	0	111.5	W41 L42 F48 V49	W41-L45 WeakPolarHBondContact O-CB 3.14Å; W41-L45 WeakPolarHBondContact O-CG 3.44Å; W41-L45 PolarHBondContact O-N 2.72Å; L42-L45 PolarHBondContact O-N 3.1Å; L45-F48 PolarHBondContact O-N 2.73Å; L45-V49 WeakPolarHBondContact O-CB 3.25Å; L45-V49 VanDerWaalsContact O-CG2 3.25Å; L45-V49 WeakPolarHBondContact O-CG2 3.25Å; L45-V49 PolarHBondContact O-N 2.69Å
46	F	95.2	Very high	89	Confident	135 Å²	135	89.2 Å²	89.2	59%	0.592	51%	0.507	S	S	*	.	H	α-helix	trans	-61.7	-48.5	178.7	-177.3	-101.8	0	0	0	111.8	L42 L43 A44 F48 V49 V50	L42-F46 VanDerWaalsContact O-CB 3.25Å; L42-F46 WeakPolarHBondContact O-CB 3.08Å; L42-F46 PolarHBondContact O-N 3.46Å; L43-F46 PolarHBondContact O-N 2.99Å; A44-F46 VanDerWaalsContact C-N 3.32Å; A44-F46 PolarHBondContact O-N 2.93Å; F46-F48 VanDerWaalsContact C-N 3.34Å; F46-F48 PolarHBondContact O-N 2.86Å; F46-V49 PolarHBondContact O-N 2.93Å; F46-V50 HydrophobicContact CD1-CG2 4.44Å; F46-V50 HydrophobicContact CD2-CG2 4.32Å; F46-V50 HydrophobicContact CE1-CG2 4.13Å; F46-V50 HydrophobicContact CE2-CG2 4.01Å; F46-V50 HydrophobicContact CZ-CG2 3.91Å; F46-V50 WeakPolarHBondContact O-CB 3.44Å; F46-V50 VanDerWaalsContact O-CG2 3.29Å; F46-V50 WeakPolarHBondContact O-CG2 3.29Å; F46-V50 PolarHBondContact O-N 3.01Å
47	I	94.2	Very high	90.2	Very high	109 Å²	109	92.2 Å²	92.2	56%	0.559	51%	0.511	S	S	*	.	H	α-helix	trans	-62.9	-42.3	177.4	-66.8	168	0	0	0	110.8	L43 A44 C51	L43-I47 WeakPolarHBondContact O-CG1 3.33Å; L43-I47 PolarHBondContact O-N 3.08Å; A44-I47 PolarHBondContact O-N 3.46Å; I47-C51 WeakPolarHBondContact O-CB 3.41Å; I47-C51 PolarHBondContact O-N 2.83Å
48	F	94.3	Very high	91.3	Very high	136 Å²	136	90.7 Å²	90.7	60%	0.596	49%	0.491	S	S	*	.	H	α-helix	trans	-62.6	-44	177.7	176.2	-101.6	0	0	0	112	A44 L45 F46 G52	A44-F48 VanDerWaalsContact O-CB 3.29Å; A44-F48 WeakPolarHBondContact O-CB 3.29Å; A44-F48 PolarHBondContact O-N 3.06Å; L45-F48 PolarHBondContact O-N 2.73Å; F46-F48 VanDerWaalsContact C-N 3.34Å; F46-F48 PolarHBondContact O-N 2.86Å; F48-G52 WeakPolarHBondContact O-CA 3.36Å; F48-G52 PolarHBondContact O-N 3.5Å
49	V	94.6	Very high	91.9	Very high	92 Å²	92	91.8 Å²	91.8	56%	0.558	49%	0.494	S	S	*	.	H	α-helix	trans	-67.6	-47	179	170.7	0	0	0	0	110.9	L45 F46 S53	L45-V49 WeakPolarHBondContact O-CB 3.25Å; L45-V49 VanDerWaalsContact O-CG2 3.25Å; L45-V49 WeakPolarHBondContact O-CG2 3.25Å; L45-V49 PolarHBondContact O-N 2.69Å; F46-V49 PolarHBondContact O-N 2.93Å; V49-S53 WeakPolarHBondContact O-CB 3.49Å; V49-S53 PolarHBondContact O-N 2.92Å; V49-S53 VanDerWaalsContact O-N 3.14Å; V49-S53 PolarHBondContact O-OG 3.26Å
50	V	94.6	Very high	92.1	Very high	78 Å²	78	94.9 Å²	94.9	47%	0.473	50%	0.499	S	S	.	.	H	α-helix	trans	-69	-53.7	-177.8	175.4	0	0	0	0	111.3	F46 S53	F46-V50 HydrophobicContact CD1-CG2 4.44Å; F46-V50 HydrophobicContact CD2-CG2 4.32Å; F46-V50 HydrophobicContact CE1-CG2 4.13Å; F46-V50 HydrophobicContact CE2-CG2 4.01Å; F46-V50 HydrophobicContact CZ-CG2 3.91Å; F46-V50 WeakPolarHBondContact O-CB 3.44Å; F46-V50 VanDerWaalsContact O-CG2 3.29Å; F46-V50 WeakPolarHBondContact O-CG2 3.29Å; F46-V50 PolarHBondContact O-N 3.01Å; V50-S53 PolarHBondContact O-OG 3.02Å
51	C	94.4	Very high	92.2	Very high	70 Å²	70	91.3 Å²	91.3	47%	0.473	48%	0.477	S	S	.	.	H	α-helix	trans	-78.4	-39	-175.4	-153.2	0	0	0	0	111.8	I47 S53 A54 I55	I47-C51 WeakPolarHBondContact O-CB 3.41Å; I47-C51 PolarHBondContact O-N 2.83Å; C51-S53 PolarHBondContact O-N 3.39Å; C51-A54 PolarHBondContact O-N 2.8Å; C51-I55 WeakPolarHBondContact O-CG1 2.91Å; C51-I55 PolarHBondContact O-N 3.01Å; C51-I55 VanDerWaalsContact O-N 3.11Å
52	G	91.6	Very high	92.1	Very high	10 Å²	10	88.1 Å²	88.1	10%	0.103	47%	0.474	C	S	.	.	H	α-helix	trans	-61.9	-40.9	176.5	0	0	0	0	0	112.1	F48 A54 I55 F56	F48-G52 WeakPolarHBondContact O-CA 3.36Å; F48-G52 PolarHBondContact O-N 3.5Å; G52-A54 VanDerWaalsContact C-N 3.31Å; G52-A54 PolarHBondContact O-N 3.49Å; G52-I55 PolarHBondContact O-N 3.08Å; G52-F56 WeakPolarHBondContact O-CD2 3.46Å; G52-F56 PolarHBondContact O-N 2.87Å
53	S	92.7	Very high	91.8	Very high	54 Å²	54	93.4 Å²	93.4	38%	0.378	49%	0.486	S	S	.	.	H	α-helix	trans	-62.3	-36.8	178	63	0	0	0	0	113.1	V49 V50 C51 Q57	V49-S53 WeakPolarHBondContact O-CB 3.49Å; V49-S53 PolarHBondContact O-N 2.92Å; V49-S53 VanDerWaalsContact O-N 3.14Å; V49-S53 PolarHBondContact O-OG 3.26Å; V50-S53 PolarHBondContact O-OG 3.02Å; C51-S53 PolarHBondContact O-N 3.39Å; S53-Q57 WeakPolarHBondContact O-CB 3.14Å; S53-Q57 VanDerWaalsContact O-CG 3.26Å; S53-Q57 WeakPolarHBondContact O-CG 3.43Å; S53-Q57 PolarHBondContact O-N 3.49Å; S53-Q57 PolarHBondContact O-NE2 3.24Å; S53-Q57 VanDerWaalsContact O-NE2 3.08Å
54	A	92.4	Very high	91.1	Very high	46 Å²	46	95 Å²	95	38%	0.38	49%	0.493	S	S	.	.	H	α-helix	trans	-66.9	-44.6	174.5	0	0	0	0	0	111.4	C51 G52 Q57 I58	C51-A54 PolarHBondContact O-N 2.8Å; G52-A54 VanDerWaalsContact C-N 3.31Å; G52-A54 PolarHBondContact O-N 3.49Å; A54-Q57 PolarHBondContact O-N 3.12Å; A54-I58 VanDerWaalsContact O-CG1 3.3Å; A54-I58 WeakPolarHBondContact O-CG1 3.32Å; A54-I58 PolarHBondContact O-N 2.92Å
55	I	93.2	Very high	90	Very high	89 Å²	89	95.8 Å²	95.8	46%	0.456	51%	0.506	S	S	.	.	H	α-helix	trans	-62.6	-46.1	177.8	-65	165.8	0	0	0	110.6	C51 G52 Q57 I58 I59	C51-I55 WeakPolarHBondContact O-CG1 2.91Å; C51-I55 PolarHBondContact O-N 3.01Å; C51-I55 VanDerWaalsContact O-N 3.11Å; G52-I55 PolarHBondContact O-N 3.08Å; I55-Q57 VanDerWaalsContact C-N 3.35Å; I55-Q57 PolarHBondContact O-N 3.36Å; I55-I58 PolarHBondContact O-N 3.01Å; I55-I59 HydrophobicContact CG2-CD1 3.68Å; I55-I59 HydrophobicContact CG2-CG1 4.36Å; I55-I59 VanDerWaalsContact O-CG1 3.3Å; I55-I59 WeakPolarHBondContact O-CG1 3.32Å; I55-I59 PolarHBondContact O-N 3.38Å
56	F	89.9	Confident	88.3	Confident	132 Å²	132	101.2 Å²	101.2	58%	0.579	53%	0.532	S	S	*	.	H	α-helix	trans	-63.1	-39.6	177.5	-80.2	-69	0	0	0	112.2	G52 I59 Q60	G52-F56 WeakPolarHBondContact O-CD2 3.46Å; G52-F56 PolarHBondContact O-N 2.87Å; F56-I59 PolarHBondContact O-N 3.4Å; F56-Q60 WeakPolarHBondContact O-CB 3.46Å; F56-Q60 PolarHBondContact O-N 3.47Å
57	Q	89.8	Confident	88	Confident	124 Å²	124	99.6 Å²	99.6	58%	0.579	53%	0.529	S	S	*	.	H	α-helix	trans	-61.2	-43.3	174	-80.3	172	75.6	0	0	112.2	S53 A54 I55 Q60 S61	S53-Q57 WeakPolarHBondContact O-CB 3.14Å; S53-Q57 VanDerWaalsContact O-CG 3.26Å; S53-Q57 WeakPolarHBondContact O-CG 3.43Å; S53-Q57 PolarHBondContact O-N 3.49Å; S53-Q57 PolarHBondContact O-NE2 3.24Å; S53-Q57 VanDerWaalsContact O-NE2 3.08Å; A54-Q57 PolarHBondContact O-N 3.12Å; I55-Q57 VanDerWaalsContact C-N 3.35Å; I55-Q57 PolarHBondContact O-N 3.36Å; Q57-Q60 PolarHBondContact O-N 3.22Å; Q57-S61 PolarHBondContact O-N 3.31Å; Q57-S61 PolarHBondContact O-OG 3.08Å
58	I	90.9	Very high	87.7	Confident	99 Å²	99	99.1 Å²	99.1	51%	0.508	53%	0.528	S	S	.	.	H	α-helix	trans	-66.1	-43.6	177.5	-65.9	163.8	0	0	0	111.1	A54 I55 Q60 S61 I62	A54-I58 VanDerWaalsContact O-CG1 3.3Å; A54-I58 WeakPolarHBondContact O-CG1 3.32Å; A54-I58 PolarHBondContact O-N 2.92Å; I55-I58 PolarHBondContact O-N 3.01Å; I58-Q60 VanDerWaalsContact C-N 3.27Å; I58-Q60 PolarHBondContact O-N 3.03Å; I58-S61 PolarHBondContact O-N 3.48Å; I58-S61 PolarHBondContact O-OG 3.29Å; I58-I62 HydrophobicContact CG2-CD1 3.78Å; I58-I62 WeakPolarHBondContact O-CB 3.3Å; I58-I62 VanDerWaalsContact O-CG1 3.24Å; I58-I62 WeakPolarHBondContact O-CG1 3.35Å; I58-I62 PolarHBondContact O-N 2.98Å
59	I	89.9	Confident	87.3	Confident	94 Å²	94	97 Å²	97	48%	0.482	52%	0.524	S	S	.	.	H	α-helix	trans	-63.9	-39.5	177.1	-67.2	168.9	0	0	0	110.2	I55 F56 R63	I55-I59 HydrophobicContact CG2-CD1 3.68Å; I55-I59 HydrophobicContact CG2-CG1 4.36Å; I55-I59 VanDerWaalsContact O-CG1 3.3Å; I55-I59 WeakPolarHBondContact O-CG1 3.32Å; I55-I59 PolarHBondContact O-N 3.38Å; F56-I59 PolarHBondContact O-N 3.4Å; I59-R63 VanDerWaalsContact O-CB 3.26Å; I59-R63 WeakPolarHBondContact O-CB 3.48Å; I59-R63 PolarHBondContact O-N 3.5Å
60	Q	87.1	Confident	86.9	Confident	96 Å²	96	97.3 Å²	97.3	45%	0.449	52%	0.522	S	S	.	.	H	α-helix	trans	-66.8	-45	178.5	-171.9	176.4	2.6	0	0	111.7	F56 Q57 I58 R63 M64	F56-Q60 WeakPolarHBondContact O-CB 3.46Å; F56-Q60 PolarHBondContact O-N 3.47Å; Q57-Q60 PolarHBondContact O-N 3.22Å; I58-Q60 VanDerWaalsContact C-N 3.27Å; I58-Q60 PolarHBondContact O-N 3.03Å; Q60-R63 PolarHBondContact O-N 2.92Å; Q60-M64 HydrophobicContact CG-CE 3.58Å; Q60-M64 HydrophobicContact CG-CG 4.24Å; Q60-M64 HydrophobicContact CG-SD 3.29Å; Q60-M64 WeakPolarHBondContact CG-SD 3.48Å; Q60-M64 PolarHBondContact NE2-SD 3.09Å; Q60-M64 VanDerWaalsContact O-CB 3.26Å; Q60-M64 WeakPolarHBondContact O-CB 3.48Å; Q60-M64 WeakPolarHBondContact O-CG 3.4Å; Q60-M64 PolarHBondContact O-N 3.29Å
61	S	90.1	Very high	86.4	Confident	42 Å²	42	98.5 Å²	98.5	29%	0.294	53%	0.525	S	S	.	.	H	α-helix	trans	-62.1	-44.3	177.8	62.7	0	0	0	0	111.5	Q57 I58 G65 M66	Q57-S61 PolarHBondContact O-N 3.31Å; Q57-S61 PolarHBondContact O-OG 3.08Å; I58-S61 PolarHBondContact O-N 3.48Å; I58-S61 PolarHBondContact O-OG 3.29Å; S61-G65 PolarHBondContact O-N 3.16Å; S61-M66 PolarHBondContact O-N 2.82Å
62	I	90.1	Very high	85.9	Confident	130 Å²	130	100.4 Å²	100.4	67%	0.667	53%	0.529	S	S	*	.	H	α-helix	trans	-64.5	-43.1	176.9	-64.5	168.1	0	0	0	111.5	I58	I58-I62 HydrophobicContact CG2-CD1 3.78Å; I58-I62 WeakPolarHBondContact O-CB 3.3Å; I58-I62 VanDerWaalsContact O-CG1 3.24Å; I58-I62 WeakPolarHBondContact O-CG1 3.35Å; I58-I62 PolarHBondContact O-N 2.98Å
63	R	84.4	Confident	85.5	Confident	213 Å²	213	106.9 Å²	106.9	80%	0.804	56%	0.559	S	S	*	*	H	α-helix	trans	-71.7	-37.7	-178.7	-176.8	179.9	176.4	99.1	0.9	112.7	I59 Q60 G65	I59-R63 VanDerWaalsContact O-CB 3.26Å; I59-R63 WeakPolarHBondContact O-CB 3.48Å; I59-R63 PolarHBondContact O-N 3.5Å; Q60-R63 PolarHBondContact O-N 2.92Å; R63-G65 VanDerWaalsContact C-N 3.34Å
64	M	77.6	Confident	84.9	Confident	112 Å²	112	110.9 Å²	110.9	55%	0.552	57%	0.573	S	S	*	*	H	α-helix	trans	-90	-3.1	-176.1	-63.7	174.7	-174.5	0	0	112.5	Q60 M66	Q60-M64 HydrophobicContact CG-CE 3.58Å; Q60-M64 HydrophobicContact CG-CG 4.24Å; Q60-M64 HydrophobicContact CG-SD 3.29Å; Q60-M64 WeakPolarHBondContact CG-SD 3.48Å; Q60-M64 PolarHBondContact NE2-SD 3.09Å; Q60-M64 VanDerWaalsContact O-CB 3.26Å; Q60-M64 WeakPolarHBondContact O-CB 3.48Å; Q60-M64 WeakPolarHBondContact O-CG 3.4Å; Q60-M64 PolarHBondContact O-N 3.29Å; M64-M66 VanDerWaalsContact C-N 3.27Å; M64-M66 HydrophobicContact CB-CG 4.07Å; M64-M66 HydrophobicContact CB-SD 4.42Å; M64-M66 PolarHBondContact O-N 3.34Å
65	G	69.3	Low	84.3	Confident	73 Å²	73	116.3 Å²	116.3	75%	0.753	59%	0.589	S	S	*	*	T	Hydrogen-bonded Turn	trans	63.9	32.3	173.6	0	0	0	0	0	113.3	S61 R63	S61-G65 PolarHBondContact O-N 3.16Å; R63-G65 VanDerWaalsContact C-N 3.34Å
66	M	59.2	Low	83.5	Confident	192 Å²	192	118.8 Å²	118.8	95%	0.946	60%	0.601	S	S	*	*			trans	-112.5	0	178.6	49.8	172	-70	0	0	111.7	S61 M64	S61-M66 PolarHBondContact O-N 2.82Å; M64-M66 VanDerWaalsContact C-N 3.27Å; M64-M66 HydrophobicContact CB-CG 4.07Å; M64-M66 HydrophobicContact CB-SD 4.42Å; M64-M66 PolarHBondContact O-N 3.34Å

Retrieved 66 of 66 residues in 23.2 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).