X5C9T4_HUMAN Loading...

RUNX1/RUNX1T1 fusion protein

AlphaFold DB , UniProt , Accession X5C9T4, Species HUMAN (Homo sapiens, Human), Gene RUNX1, Length 21 aa.

						>X5C9T4_HUMAN|X5C9T4|RUNX1
MASDSIFESFPSYPQCFMRDE
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	47.7	Very low	66.7	Low	231 Å²	231	112.6 Å²	112.6	100%	1.138	63%	0.634	S	S	*	*				0	112	0	-81.9	-72.2	142.3	0	0	105.4	S3	M1-S3 PolarHBondContact O-N 2.9Å
2	A	58.7	Low	67.2	Low	87 Å²	87	112.3 Å²	112.3	72%	0.719	64%	0.644	S	S	*	*			trans	-59.6	112.8	166.3	0	0	0	0	0	105	D4	A2-D4 VanDerWaalsContact C-N 3.3Å; A2-D4 PolarHBondContact O-N 3.18Å
3	S	60.2	Low	67.8	Low	89 Å²	89	110.1 Å²	110.1	62%	0.622	62%	0.62	S	S	*	*			trans	-67.2	102.3	168.8	164.5	0	0	0	0	103.9	M1 S5	M1-S3 PolarHBondContact O-N 2.9Å; S3-S5 PolarHBondContact O-N 2.97Å
4	D	65.7	Low	68.2	Low	141 Å²	141	106.9 Å²	106.9	75%	0.754	61%	0.605	S	S	*	*			trans	-63.3	78.7	166.3	-69.4	-32.4	0	0	0	106.6	A2 I6	A2-D4 VanDerWaalsContact C-N 3.3Å; A2-D4 PolarHBondContact O-N 3.18Å; D4-I6 PolarHBondContact O-N 2.98Å
5	S	72.1	Confident	68.3	Low	29 Å²	29	108 Å²	108	20%	0.203	60%	0.604	C	S	.	*			trans	-68.3	126.7	-174.2	-173.1	0	0	0	0	105.8	S3 F7 E8	S3-S5 PolarHBondContact O-N 2.97Å; S5-F7 PolarHBondContact O-N 3.28Å; S5-F7 WeakPolarHBondContact OG-CD2 3.48Å; S5-E8 WeakPolarHBondContact O-CB 3.37Å; S5-E8 PolarHBondContact O-N 3.02Å
6	I	72.8	Confident	68.6	Low	109 Å²	109	108.8 Å²	108.8	56%	0.559	62%	0.617	S	S	*	*	H	α-helix	trans	-51.5	-26.5	178.1	59.8	167.3	0	0	0	111.5	D4 E8 S9 F10	D4-I6 PolarHBondContact O-N 2.98Å; I6-E8 VanDerWaalsContact C-N 3.34Å; I6-E8 PolarHBondContact O-N 3.35Å; I6-S9 VanDerWaalsContact O-N 3.17Å; I6-S9 PolarHBondContact O-N 2.96Å; I6-S9 WeakPolarHBondContact O-CB 3.43Å; I6-F10 WeakPolarHBondContact O-CD2 3.16Å; I6-F10 PolarHBondContact O-N 3.02Å
7	F	69	Low	68.7	Low	62 Å²	62	111.1 Å²	111.1	27%	0.272	62%	0.619	S	S	.	*	H	α-helix	trans	-66.8	-30.1	176.9	-53.7	-54.7	0	0	0	113.4	S5 S9 F10 Y13 M18	S5-F7 PolarHBondContact O-N 3.28Å; S5-F7 WeakPolarHBondContact OG-CD2 3.48Å; F7-S9 VanDerWaalsContact C-N 3.3Å; F7-F10 PolarHBondContact O-N 3.25Å; F7-Y13 AromaticContact CE1-CZ 3.43Å; F7-Y13 HydrophobicContact CZ-CE1 4.27Å; F7-Y13 HydrophobicContact CG-CD1 4.32Å; F7-Y13 VanDerWaalsContact CE1-CZ 3.43Å; F7-Y13 HydrophobicContact CE1-CG 4.34Å; F7-Y13 HydrophobicContact CE1-CE2 4.14Å; F7-Y13 HydrophobicContact CE1-CE1 3.18Å; F7-Y13 AromaticContact CE1-CE1 3.18Å; F7-Y13 HydrophobicContact CE1-CD1 3.69Å; F7-Y13 AromaticContact CD1-CZ 3.9Å; F7-Y13 AromaticContact CE1-CD1 3.69Å; F7-Y13 AromaticContact CD1-CD1 3.3Å; F7-Y13 HydrophobicContact CD1-CD1 3.3Å; F7-Y13 HydrophobicContact CD1-CD2 4.28Å; F7-Y13 AromaticContact CD1-CE1 3.36Å; F7-Y13 HydrophobicContact CD1-CE1 3.36Å; F7-Y13 HydrophobicContact CD1-CE2 4.34Å; F7-Y13 AromaticContact CD1-CG 3.78Å; F7-Y13 HydrophobicContact CD1-CG 3.78Å; F7-M18 HydrophobicContact CB-CE 3.43Å; F7-M18 VanDerWaalsContact CB-CE 3.43Å; F7-M18 HydrophobicContact CB-SD 3.95Å; F7-M18 HydrophobicContact CD2-CE 3.73Å; F7-M18 HydrophobicContact CG-CE 3.75Å; F7-M18 HydrophobicContact CG-SD 4.19Å
8	E	68.9	Low	68.7	Low	151 Å²	151	108.4 Å²	108.4	71%	0.706	60%	0.602	S	S	*	*	H	α-helix	trans	-72.8	-25.5	173.4	-64.8	-179	-176.2	0	0	112	S5 I6 F10	S5-E8 WeakPolarHBondContact O-CB 3.37Å; S5-E8 PolarHBondContact O-N 3.02Å; I6-E8 VanDerWaalsContact C-N 3.34Å; I6-E8 PolarHBondContact O-N 3.35Å; E8-F10 VanDerWaalsContact C-N 3.29Å
9	S	75.3	Confident	68.9	Low	87 Å²	87	115.2 Å²	115.2	61%	0.608	62%	0.617	S	S	*	*	H	α-helix	trans	-76.2	-17	176	-60.6	0	0	0	0	113.2	I6 F7 P11	I6-S9 VanDerWaalsContact O-N 3.17Å; I6-S9 PolarHBondContact O-N 2.96Å; I6-S9 WeakPolarHBondContact O-CB 3.43Å; F7-S9 VanDerWaalsContact C-N 3.3Å; S9-P11 WeakPolarHBondContact O-CD 3.22Å
10	F	77.1	Confident	68.8	Low	121 Å²	121	117.5 Å²	117.5	53%	0.531	63%	0.629	S	S	.	*			trans	-120.8	89.9	-179	-65.5	-69.6	0	0	0	110.2	I6 F7 E8 S12 Y13	I6-F10 WeakPolarHBondContact O-CD2 3.16Å; I6-F10 PolarHBondContact O-N 3.02Å; F7-F10 PolarHBondContact O-N 3.25Å; E8-F10 VanDerWaalsContact C-N 3.29Å; F10-S12 PolarHBondContact O-N 3.37Å; F10-Y13 PolarHBondContact O-N 3.17Å; F10-Y13 WeakPolarHBondContact O-CB 3.39Å
11	P	66.4	Low	68.2	Low	132 Å²	132	124.6 Å²	124.6	86%	0.857	66%	0.659	S	S	*	*	T	Hydrogen-bonded Turn	trans	-62.3	-14.5	-175.5	21.3	-31.2	0	0	0	114.4	S9	S9-P11 WeakPolarHBondContact O-CD 3.22Å
12	S	72.4	Confident	69.3	Low	108 Å²	108	119.3 Å²	119.3	76%	0.755	64%	0.635	S	S	*	*	T	Hydrogen-bonded Turn	trans	-104.3	9.2	175.4	66.8	0	0	0	0	113.9	F10	F10-S12 PolarHBondContact O-N 3.37Å
13	Y	75.5	Confident	69.8	Low	84 Å²	84	120.9 Å²	120.9	33%	0.329	63%	0.63	S	S	.	*	S	Bend	trans	-64.2	127.8	179.3	-167.7	-94.2	0	0	0	109.6	F7 F10 Q15 F17	F7-Y13 AromaticContact CE1-CZ 3.43Å; F7-Y13 HydrophobicContact CZ-CE1 4.27Å; F7-Y13 HydrophobicContact CG-CD1 4.32Å; F7-Y13 VanDerWaalsContact CE1-CZ 3.43Å; F7-Y13 HydrophobicContact CE1-CG 4.34Å; F7-Y13 HydrophobicContact CE1-CE2 4.14Å; F7-Y13 HydrophobicContact CE1-CE1 3.18Å; F7-Y13 AromaticContact CE1-CE1 3.18Å; F7-Y13 HydrophobicContact CE1-CD1 3.69Å; F7-Y13 AromaticContact CD1-CZ 3.9Å; F7-Y13 AromaticContact CE1-CD1 3.69Å; F7-Y13 AromaticContact CD1-CD1 3.3Å; F7-Y13 HydrophobicContact CD1-CD1 3.3Å; F7-Y13 HydrophobicContact CD1-CD2 4.28Å; F7-Y13 AromaticContact CD1-CE1 3.36Å; F7-Y13 HydrophobicContact CD1-CE1 3.36Å; F7-Y13 HydrophobicContact CD1-CE2 4.34Å; F7-Y13 AromaticContact CD1-CG 3.78Å; F7-Y13 HydrophobicContact CD1-CG 3.78Å; F10-Y13 PolarHBondContact O-N 3.17Å; F10-Y13 WeakPolarHBondContact O-CB 3.39Å; Y13-Q15 PolarHBondContact O-N 3.46Å; Y13-Q15 PolarHBondContact O-NE2 2.66Å; Y13-F17 HydrophobicContact CE1-CB 4.17Å; Y13-F17 HydrophobicContact CE1-CD2 4.38Å
14	P	72.4	Confident	70.3	Confident	65 Å²	65	122.7 Å²	122.7	42%	0.422	63%	0.631	S	S	.	*			trans	-59.4	113.8	-175.3	-20.9	30.4	0	0	0	110.5	C16 F17	P14-C16 PolarHBondContact O-N 3.31Å; P14-F17 HydrophobicContact CB-CD2 4.03Å; P14-F17 HydrophobicContact CB-CE2 4.16Å; P14-F17 HydrophobicContact CG-CE2 4.42Å; P14-F17 PolarHBondContact O-N 3.4Å
15	Q	70.8	Confident	70.6	Confident	124 Å²	124	121.6 Å²	121.6	58%	0.579	62%	0.623	S	S	*	*	G	3₁₀ helix	trans	-60.3	-15.9	176.9	-61.3	-64.5	-70.3	0	0	111.9	Y13 F17 M18	Y13-Q15 PolarHBondContact O-N 3.46Å; Y13-Q15 PolarHBondContact O-NE2 2.66Å; Q15-F17 PolarHBondContact O-N 3.47Å; Q15-M18 VanDerWaalsContact CD-SD 3.54Å; Q15-M18 PolarHBondContact NE2-SD 2.81Å; Q15-M18 PolarHBondContact O-N 3.03Å; Q15-M18 PolarHBondContact OE1-SD 3.03Å; Q15-M18 VanDerWaalsContact OE1-SD 3.35Å
16	C	72.8	Confident	70.5	Confident	121 Å²	121	127.4 Å²	127.4	82%	0.818	65%	0.65	S	S	*	*	G	3₁₀ helix	trans	-54.9	-20.6	174.4	-53.5	0	0	0	0	114.6	P14	P14-C16 PolarHBondContact O-N 3.31Å
17	F	69.9	Low	70.4	Confident	147 Å²	147	128.7 Å²	128.7	65%	0.645	66%	0.656	S	S	*	*	G	3₁₀ helix	trans	-99.9	-10.3	177.7	-62.9	-75	0	0	0	113.6	Y13 P14 Q15 R19	Y13-F17 HydrophobicContact CE1-CB 4.17Å; Y13-F17 HydrophobicContact CE1-CD2 4.38Å; P14-F17 HydrophobicContact CB-CD2 4.03Å; P14-F17 HydrophobicContact CB-CE2 4.16Å; P14-F17 HydrophobicContact CG-CE2 4.42Å; P14-F17 PolarHBondContact O-N 3.4Å; Q15-F17 PolarHBondContact O-N 3.47Å; F17-R19 PolarHBondContact O-N 2.91Å; F17-R19 VanDerWaalsContact O-N 3.15Å
18	M	69.3	Low	70.5	Confident	63 Å²	63	133.4 Å²	133.4	31%	0.31	68%	0.683	S	S	.	*			trans	-82.5	93.5	175.4	-60	-178.1	87.3	0	0	106.2	F7 Q15 D20	F7-M18 HydrophobicContact CB-CE 3.43Å; F7-M18 VanDerWaalsContact CB-CE 3.43Å; F7-M18 HydrophobicContact CB-SD 3.95Å; F7-M18 HydrophobicContact CD2-CE 3.73Å; F7-M18 HydrophobicContact CG-CE 3.75Å; F7-M18 HydrophobicContact CG-SD 4.19Å; Q15-M18 VanDerWaalsContact CD-SD 3.54Å; Q15-M18 PolarHBondContact NE2-SD 2.81Å; Q15-M18 PolarHBondContact O-N 3.03Å; Q15-M18 PolarHBondContact OE1-SD 3.03Å; Q15-M18 VanDerWaalsContact OE1-SD 3.35Å; M18-D20 PolarHBondContact O-N 3.27Å
19	R	73.1	Confident	70.6	Confident	238 Å²	238	132.1 Å²	132.1	90%	0.898	68%	0.681	S	S	*	*			trans	-82.8	104.4	177.8	-169.8	178.3	-71.3	-163.7	-2.2	107	F17 E21	F17-R19 PolarHBondContact O-N 2.91Å; F17-R19 VanDerWaalsContact O-N 3.15Å; R19-E21 PolarHBondContact O-N 3.15Å
20	D	66.2	Low	70.2	Confident	161 Å²	161	135.8 Å²	135.8	86%	0.861	69%	0.687	S	S	*	*			trans	-64.4	115.7	171.4	-61.3	-62.3	0	0	0	108.5	M18	M18-D20 PolarHBondContact O-N 3.27Å
21	E	56.8	Low	69.6	Low	266 Å²	266	137.2 Å²	137.2	100%	1.243	70%	0.702	S	S	*	*			trans	-90.1	0	162.7	-173.7	171.8	110.6	0	0	109.5	R19	R19-E21 PolarHBondContact O-N 3.15Å

Retrieved 21 of 21 residues in 44.8 ms (Link to these results)

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