X5CR15_HUMAN Loading...

RUNX1/RUNX1T1 fusion protein

AlphaFold DB , UniProt , Accession X5CR15, Species HUMAN (Homo sapiens, Human), Gene RUNX1, Length 34 aa.

						>X5CR15_HUMAN|X5CR15|RUNX1
MASDSIFESFPSYPQCFMRECILGMNPSRDVHDE
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	50.5	Low	60.1	Low	232 Å²	232	114 Å²	114	100%	1.143	65%	0.651	S	S	*	*				0	108.4	0	-72.8	-160	111.5	0	0	107.5
2	A	55.7	Low	60.8	Low	104 Å²	104	114.1 Å²	114.1	86%	0.86	66%	0.664	S	S	*	*			trans	-149.1	57.7	-175.3	0	0	0	0	0	109.1
3	S	55.6	Low	61.2	Low	81 Å²	81	112.7 Å²	112.7	57%	0.566	64%	0.642	S	S	*	*			trans	-134.1	-2.8	175.8	-137.4	0	0	0	0	114.1	S5	S3-S5 PolarHBondContact O-N 3.34Å
4	D	58.1	Low	61.8	Low	119 Å²	119	110 Å²	110	64%	0.636	63%	0.631	S	S	*	*	S	Bend	trans	-75.6	-10.7	177.4	-59	-59.9	0	0	0	113.1
5	S	62.7	Low	62.2	Low	88 Å²	88	108.3 Å²	108.3	62%	0.615	62%	0.615	S	S	*	*	H	α-helix	trans	-90.2	-22.4	-166.4	-175.6	0	0	0	0	116.4	S3 S9	S3-S5 PolarHBondContact O-N 3.34Å; S5-S9 PolarHBondContact O-OG 2.93Å
6	I	64.4	Low	62.4	Low	105 Å²	105	107.9 Å²	107.9	54%	0.538	62%	0.619	S	S	.	*	H	α-helix	trans	-83.4	-32.7	-174.5	-57.9	176.7	0	0	0	110.8	F10	I6-F10 WeakPolarHBondContact O-CD2 3.48Å
7	F	59.5	Low	62.5	Low	45 Å²	45	108.2 Å²	108.2	20%	0.197	61%	0.612	C	S	.	*	H	α-helix	trans	-85	-31.7	-173.9	-66.1	-80.3	0	0	0	113.8	S9 Q15 M18 I22	F7-S9 PolarHBondContact O-N 3.15Å; F7-Q15 VanDerWaalsContact CD1-OE1 3.3Å; F7-Q15 PolarHBondContact O-NE2 3.49Å; F7-M18 HydrophobicContact CZ-SD 3.51Å; F7-M18 VanDerWaalsContact CZ-SD 3.51Å; F7-M18 HydrophobicContact CZ-CG 4.31Å; F7-M18 HydrophobicContact CZ-CE 3.79Å; F7-M18 HydrophobicContact CZ-CB 3.99Å; F7-M18 HydrophobicContact CG-CE 4.43Å; F7-M18 WeakPolarHBondContact CE1-SD 3.41Å; F7-M18 HydrophobicContact CE1-SD 3.23Å; F7-M18 HydrophobicContact CE1-CE 3.09Å; F7-M18 VanDerWaalsContact CE1-CB 3.41Å; F7-M18 HydrophobicContact CE1-CB 3.41Å; F7-M18 HydrophobicContact CD1-SD 4.2Å; F7-M18 VanDerWaalsContact CD1-CE 3.45Å; F7-M18 HydrophobicContact CD1-CE 3.45Å; F7-M18 HydrophobicContact CD1-CB 4.5Å; F7-M18 HydrophobicContact CE1-CG 3.66Å; F7-I22 HydrophobicContact CE2-CD1 4.12Å; F7-I22 HydrophobicContact CZ-CD1 3.57Å
8	E	60.3	Low	62.6	Low	164 Å²	164	104.1 Å²	104.1	77%	0.766	59%	0.587	S	S	*	*	H	α-helix	trans	-68.6	-24.8	173.6	-79.2	-159.3	105.3	0	0	112.8	F10	E8-F10 VanDerWaalsContact C-N 3.26Å; E8-F10 PolarHBondContact O-N 3.48Å
9	S	67.4	Low	62.7	Low	78 Å²	78	108.3 Å²	108.3	55%	0.545	59%	0.593	S	S	.	*	T	Hydrogen-bonded Turn	trans	-73.8	-16.3	-178.7	-60.8	0	0	0	0	113.5	S5 F7	S5-S9 PolarHBondContact O-OG 2.93Å; F7-S9 PolarHBondContact O-N 3.15Å
10	F	66.5	Low	62.9	Low	119 Å²	119	110 Å²	110	52%	0.522	60%	0.597	S	S	.	*			trans	-129.9	80.2	-178.9	-58.9	-83.3	0	0	0	111.2	I6 E8 S12 Y13	I6-F10 WeakPolarHBondContact O-CD2 3.48Å; E8-F10 VanDerWaalsContact C-N 3.26Å; E8-F10 PolarHBondContact O-N 3.48Å; F10-S12 PolarHBondContact O-N 2.76Å; F10-Y13 PolarHBondContact O-N 3.05Å
11	P	60.1	Low	63	Low	119 Å²	119	107.2 Å²	107.2	77%	0.773	59%	0.585	S	S	*	*	T	Hydrogen-bonded Turn	trans	-60.5	-19.4	-177	21.7	-32.4	0	0	0	113.9
12	S	69.3	Low	63.6	Low	115 Å²	115	100.6 Å²	100.6	80%	0.804	55%	0.553	S	S	*	*	T	Hydrogen-bonded Turn	trans	-105.8	-1.1	179	-41.8	0	0	0	0	114.3	F10	F10-S12 PolarHBondContact O-N 2.76Å
13	Y	65.8	Low	64	Low	96 Å²	96	101.7 Å²	101.7	38%	0.376	54%	0.544	S	S	.	.	S	Bend	trans	-70.4	130.9	176.7	-164.5	-84.5	0	0	0	108.4	F10 Q15 F17 M18	F10-Y13 PolarHBondContact O-N 3.05Å; Y13-Q15 PolarHBondContact O-N 3.13Å; Y13-F17 HydrophobicContact CE1-CD1 4.43Å; Y13-M18 HydrophobicContact CD1-CE 3.66Å; Y13-M18 HydrophobicContact CD1-CG 3.71Å; Y13-M18 HydrophobicContact CD1-SD 4.44Å; Y13-M18 HydrophobicContact CE1-CB 4.42Å; Y13-M18 HydrophobicContact CE1-CE 3.79Å; Y13-M18 HydrophobicContact CE1-CG 3.18Å; Y13-M18 HydrophobicContact CE1-SD 4.03Å; Y13-M18 HydrophobicContact CG-CE 4.24Å
14	P	69.3	Low	64.4	Low	75 Å²	75	101 Å²	101	49%	0.487	55%	0.55	S	S	.	*			trans	-61.9	97.6	-178	22.7	-31.1	0	0	0	109.8	C16 F17 M18	P14-C16 VanDerWaalsContact O-N 3.15Å; P14-C16 PolarHBondContact O-N 2.84Å; P14-F17 HydrophobicContact CB-CB 4.21Å; P14-F17 PolarHBondContact O-N 3.01Å; P14-F17 HydrophobicContact CG-CB 4.11Å; P14-F17 WeakPolarHBondContact O-CB 3.02Å; P14-M18 PolarHBondContact O-N 3.03Å
15	Q	67.6	Low	64.5	Low	85 Å²	85	102.5 Å²	102.5	40%	0.397	56%	0.555	S	S	.	*	H	α-helix	trans	-56.6	-31.5	179.5	-62.2	-68.1	-35.2	0	0	111	F7 Y13 F17 R19	F7-Q15 VanDerWaalsContact CD1-OE1 3.3Å; F7-Q15 PolarHBondContact O-NE2 3.49Å; Y13-Q15 PolarHBondContact O-N 3.13Å; Q15-F17 VanDerWaalsContact C-N 3.31Å; Q15-F17 PolarHBondContact O-N 3.41Å; Q15-R19 WeakPolarHBondContact O-CB 3.33Å; Q15-R19 PolarHBondContact O-N 2.83Å; Q15-R19 VanDerWaalsContact O-N 3.13Å
16	C	65.2	Low	64.4	Low	101 Å²	101	104.5 Å²	104.5	68%	0.682	56%	0.559	S	S	*	*	H	α-helix	trans	-56.7	-42.7	173.4	-55.4	0	0	0	0	112.2	P14 E20	P14-C16 VanDerWaalsContact O-N 3.15Å; P14-C16 PolarHBondContact O-N 2.84Å; C16-E20 PolarHBondContact O-N 3.25Å
17	F	63.9	Low	64.1	Low	114 Å²	114	104.2 Å²	104.2	50%	0.5	56%	0.563	S	S	.	*	H	α-helix	trans	-71.3	-46	-176.4	-176.1	-102.5	0	0	0	112.1	Y13 P14 Q15 R19 E20 C21	Y13-F17 HydrophobicContact CE1-CD1 4.43Å; P14-F17 HydrophobicContact CB-CB 4.21Å; P14-F17 PolarHBondContact O-N 3.01Å; P14-F17 HydrophobicContact CG-CB 4.11Å; P14-F17 WeakPolarHBondContact O-CB 3.02Å; Q15-F17 VanDerWaalsContact C-N 3.31Å; Q15-F17 PolarHBondContact O-N 3.41Å; F17-R19 VanDerWaalsContact C-N 3.34Å; F17-R19 PolarHBondContact O-N 2.97Å; F17-E20 PolarHBondContact O-N 3.46Å; F17-C21 VanDerWaalsContact CE1-SG 3.55Å; F17-C21 PolarHBondContact O-N 3.06Å; F17-C21 PolarHBondContact O-SG 3.37Å
18	M	65.7	Low	64.1	Low	33 Å²	33	105.9 Å²	105.9	16%	0.163	58%	0.581	C	S	.	*	H	α-helix	trans	-67.6	-33.7	178.5	-75.5	-133	-112.5	0	0	113.3	F7 Y13 P14 E20 C21 I22	F7-M18 HydrophobicContact CZ-SD 3.51Å; F7-M18 VanDerWaalsContact CZ-SD 3.51Å; F7-M18 HydrophobicContact CZ-CG 4.31Å; F7-M18 HydrophobicContact CZ-CE 3.79Å; F7-M18 HydrophobicContact CZ-CB 3.99Å; F7-M18 HydrophobicContact CG-CE 4.43Å; F7-M18 WeakPolarHBondContact CE1-SD 3.41Å; F7-M18 HydrophobicContact CE1-SD 3.23Å; F7-M18 HydrophobicContact CE1-CE 3.09Å; F7-M18 VanDerWaalsContact CE1-CB 3.41Å; F7-M18 HydrophobicContact CE1-CB 3.41Å; F7-M18 HydrophobicContact CD1-SD 4.2Å; F7-M18 VanDerWaalsContact CD1-CE 3.45Å; F7-M18 HydrophobicContact CD1-CE 3.45Å; F7-M18 HydrophobicContact CD1-CB 4.5Å; F7-M18 HydrophobicContact CE1-CG 3.66Å; Y13-M18 HydrophobicContact CD1-CE 3.66Å; Y13-M18 HydrophobicContact CD1-CG 3.71Å; Y13-M18 HydrophobicContact CD1-SD 4.44Å; Y13-M18 HydrophobicContact CE1-CB 4.42Å; Y13-M18 HydrophobicContact CE1-CE 3.79Å; Y13-M18 HydrophobicContact CE1-CG 3.18Å; Y13-M18 HydrophobicContact CE1-SD 4.03Å; Y13-M18 HydrophobicContact CG-CE 4.24Å; P14-M18 PolarHBondContact O-N 3.03Å; M18-E20 VanDerWaalsContact C-N 3.27Å; M18-E20 PolarHBondContact O-N 3.25Å; M18-C21 PolarHBondContact O-N 3.43Å; M18-I22 PolarHBondContact O-N 3.44Å; M18-I22 WeakPolarHBondContact O-CG1 3.38Å
19	R	64.1	Low	64.1	Low	184 Å²	184	109.3 Å²	109.3	69%	0.694	59%	0.587	S	S	*	*	H	α-helix	trans	-59.2	-43.8	174.6	177.6	179.3	-89.4	-169.4	-4.9	110.1	Q15 F17 I22 L23	Q15-R19 WeakPolarHBondContact O-CB 3.33Å; Q15-R19 PolarHBondContact O-N 2.83Å; Q15-R19 VanDerWaalsContact O-N 3.13Å; F17-R19 VanDerWaalsContact C-N 3.34Å; F17-R19 PolarHBondContact O-N 2.97Å; R19-I22 PolarHBondContact O-N 3.01Å; R19-L23 HydrophobicContact CG-CD1 3.77Å; R19-L23 HydrophobicContact CG-CG 4.48Å; R19-L23 WeakPolarHBondContact O-CB 3.23Å; R19-L23 WeakPolarHBondContact O-CD1 3.19Å; R19-L23 WeakPolarHBondContact O-CG 3.47Å; R19-L23 PolarHBondContact O-N 3.19Å
20	E	65.6	Low	63.6	Low	142 Å²	142	112.2 Å²	112.2	66%	0.664	60%	0.596	S	S	*	*	H	α-helix	trans	-65.7	-39.6	174.3	-73.2	-171.6	98.3	0	0	112.4	C16 F17 M18 L23 G24	C16-E20 PolarHBondContact O-N 3.25Å; F17-E20 PolarHBondContact O-N 3.46Å; M18-E20 VanDerWaalsContact C-N 3.27Å; M18-E20 PolarHBondContact O-N 3.25Å; E20-L23 PolarHBondContact O-N 3.44Å; E20-G24 PolarHBondContact O-N 3.09Å
21	C	65	Low	63.3	Low	53 Å²	53	112.2 Å²	112.2	36%	0.358	61%	0.605	S	S	.	*	H	α-helix	trans	-62.3	-44.3	175.3	-63.5	0	0	0	0	112.5	F17 M18 M25	F17-C21 VanDerWaalsContact CE1-SG 3.55Å; F17-C21 PolarHBondContact O-N 3.06Å; F17-C21 PolarHBondContact O-SG 3.37Å; M18-C21 PolarHBondContact O-N 3.43Å; C21-M25 WeakPolarHBondContact O-CB 3.49Å; C21-M25 PolarHBondContact O-N 3.46Å
22	I	64.8	Low	63.3	Low	92 Å²	92	115.2 Å²	115.2	47%	0.472	61%	0.609	S	S	.	*	H	α-helix	trans	-67.7	-40.3	-179.7	-67.5	163.4	0	0	0	111	F7 M18 R19	F7-I22 HydrophobicContact CE2-CD1 4.12Å; F7-I22 HydrophobicContact CZ-CD1 3.57Å; M18-I22 PolarHBondContact O-N 3.44Å; M18-I22 WeakPolarHBondContact O-CG1 3.38Å; R19-I22 PolarHBondContact O-N 3.01Å
23	L	63.8	Low	62.7	Low	128 Å²	128	117.9 Å²	117.9	67%	0.67	61%	0.614	S	S	*	*	H	α-helix	trans	-72.7	-35.3	179.3	-67.3	171.7	0	0	0	112.2	R19 E20	R19-L23 HydrophobicContact CG-CD1 3.77Å; R19-L23 HydrophobicContact CG-CG 4.48Å; R19-L23 WeakPolarHBondContact O-CB 3.23Å; R19-L23 WeakPolarHBondContact O-CD1 3.19Å; R19-L23 WeakPolarHBondContact O-CG 3.47Å; R19-L23 PolarHBondContact O-N 3.19Å; E20-L23 PolarHBondContact O-N 3.44Å
24	G	63.1	Low	62.3	Low	67 Å²	67	125.9 Å²	125.9	69%	0.691	66%	0.655	S	S	*	*	H	α-helix	trans	-80.7	-14.1	177.7	0	0	0	0	0	114.7	E20	E20-G24 PolarHBondContact O-N 3.09Å
25	M	61.2	Low	61.9	Low	150 Å²	150	128.5 Å²	128.5	74%	0.739	66%	0.663	S	S	*	*	T	Hydrogen-bonded Turn	trans	-99.5	21.7	-175.9	-157.8	158.4	85.4	0	0	113.4	C21 P27	C21-M25 WeakPolarHBondContact O-CB 3.49Å; C21-M25 PolarHBondContact O-N 3.46Å; M25-P27 WeakPolarHBondContact O-CD 2.93Å
26	N	60.3	Low	61.6	Low	130 Å²	130	130.7 Å²	130.7	70%	0.695	68%	0.677	S	S	*	*			trans	-91	87.5	157.2	-94.5	-82	0	0	0	109.1	S28	N26-S28 PolarHBondContact O-N 3.34Å; N26-S28 VanDerWaalsContact O-N 3.09Å
27	P	57.5	Low	61.4	Low	98 Å²	98	132.4 Å²	132.4	64%	0.636	68%	0.677	S	S	*	*			trans	-61.8	113.6	151.3	28.2	-28.1	0	0	0	105.5	M25 R29	M25-P27 WeakPolarHBondContact O-CD 2.93Å; P27-R29 PolarHBondContact O-N 3.05Å
28	S	60.4	Low	61.3	Low	80 Å²	80	133.5 Å²	133.5	56%	0.559	69%	0.688	S	S	*	*			trans	-49.1	111.6	169.8	172.4	0	0	0	0	107.1	N26 D30	N26-S28 PolarHBondContact O-N 3.34Å; N26-S28 VanDerWaalsContact O-N 3.09Å; S28-D30 PolarHBondContact O-N 2.91Å; S28-D30 PolarHBondContact OG-OD2 3.44Å
29	R	59.2	Low	61	Low	237 Å²	237	139.8 Å²	139.8	89%	0.894	72%	0.72	S	S	*	*	S	Bend	trans	-76.2	20.2	179.7	-78.7	179.2	60.8	-163.2	-3.3	111.6	P27	P27-R29 PolarHBondContact O-N 3.05Å
30	D	57.9	Low	60.8	Low	139 Å²	139	136.8 Å²	136.8	74%	0.743	72%	0.722	S	S	*	*			trans	-106.4	29.5	-173.2	-63.2	-82.1	0	0	0	112.4	S28	S28-D30 PolarHBondContact O-N 2.91Å; S28-D30 PolarHBondContact OG-OD2 3.44Å
31	V	59.3	Low	60.4	Low	118 Å²	118	136.4 Å²	136.4	72%	0.715	73%	0.726	S	S	*	*	S	Bend	trans	-119.5	14.4	176.9	-167.1	0	0	0	0	112.6
32	H	61.1	Low	60.1	Low	182 Å²	182	142.8 Å²	142.8	84%	0.843	76%	0.755	S	S	*	*			trans	-138.8	70.9	169.6	-86.5	38.8	0	0	0	109.8
33	D	56.3	Low	59.7	Low	171 Å²	171	147.1 Å²	147.1	91%	0.914	78%	0.778	S	S	*	*			trans	-137.6	80.4	152.5	-156	-106	0	0	0	105.1
34	E	56.2	Low	59.3	Low	265 Å²	265	148.8 Å²	148.8	100%	1.238	79%	0.788	S	S	*	*			trans	-104.5	0	162	-173.2	-172.4	101.4	0	0	107.5

Retrieved 34 of 34 residues in 11.3 ms (Link to these results)

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