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Vasopressin V1a receptor

Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

AlphaFold DB (P37288), UniProt , Accession X5D2B0, Species HUMAN (Homo sapiens, Human), Gene AVPR1A, Length 418 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	44.6	Very low	33.5	Very low	52 Å²	52	77 Å²	77	26%	0.256	52%	0.521	S	S	.	.				0	116.9	0	-75.3	171.2	-165.7	0	0	107.6	V132 F189 Y216 M220	M1-V132 HydrophobicContact CE-CG2 3.12Å; M1-F189 HydrophobicContact SD-CZ 4.43Å; M1-Y216 HydrophobicContact SD-CE1 3.88Å; M1-Y216 PolarHBondContact SD-OH 3.45Å; M1-M220 HydrophobicContact CE-CE 3.58Å; M1-M220 HydrophobicContact SD-CE 4.21Å
2	R	44.2	Very low	33.2	Very low	86 Å²	86	80.2 Å²	80.2	33%	0.325	55%	0.545	S	S	.	.			trans	-78.7	120.9	171.3	-66	-178.9	-176.8	176.5	7.9	108	D112	R2-D112 IonicContact NH2-OD1 2.76Å; R2-D112 PolarHBondContact NH2-OD1 3.39Å
3	L	40	Very low	32.7	Very low	46 Å²	46	79.3 Å²	79.3	24%	0.241	56%	0.558	C	S	.	*			trans	-125	120.9	173.4	-62.3	170.7	0	0	0	105.5	A205 F207 Y216 V217	L3-A205 HydrophobicContact CD2-CB 3.55Å; L3-F207 HydrophobicContact CD2-CE2 4.08Å; L3-F207 HydrophobicContact CD2-CZ 4.19Å; L3-Y216 HydrophobicContact CD1-CD1 3.92Å; L3-Y216 HydrophobicContact CD1-CE1 4.13Å; L3-Y216 HydrophobicContact CD2-CD1 4.39Å; L3-Y216 HydrophobicContact CD2-CE1 4.36Å; L3-V217 HydrophobicContact CD1-CG2 3.34Å
4	S	34.5	Very low	32.4	Very low	21 Å²	21	84.8 Å²	84.8	15%	0.147	58%	0.577	C	S	.	*			trans	-154.8	99.3	-170.4	-111.8	0	0	0	0	110	G6 W204 E324	S4-G6 PolarHBondContact O-N 3.02Å; S4-W204 VanDerWaalsContact C-CZ2 3.48Å; S4-W204 WeakPolarHBondContact O-CH2 3.31Å; S4-W204 WeakPolarHBondContact O-CZ2 3.39Å; S4-W204 VanDerWaalsContact O-CZ3 3.32Å; S4-W204 WeakPolarHBondContact O-CZ3 3.26Å; S4-E324 WeakPolarHBondContact CA-OE1 3.12Å; S4-E324 WeakPolarHBondContact CB-OE1 3.47Å; S4-E324 WeakPolarHBondContact OG-CA 3.48Å; S4-E324 WeakPolarHBondContact OG-CB 3.44Å; S4-E324 WeakPolarHBondContact OG-CG 3.28Å; S4-E324 PolarHBondContact OG-OE1 3.37Å
5	A	30.5	Very low	32.1	Very low	92 Å²	92	85.8 Å²	85.8	76%	0.76	59%	0.586	S	S	*	*			trans	-40.4	115.5	-170.3	0	0	0	0	0	111.5	E324	A5-E324 PolarHBondContact N-OE1 3.47Å
6	G	29.3	Very low	32.1	Very low	36 Å²	36	87.2 Å²	87.2	37%	0.371	60%	0.596	S	S	.	*			trans	-51.2	153.4	-174.5	0	0	0	0	0	111.7	S4 D8	S4-G6 PolarHBondContact O-N 3.02Å; G6-D8 PolarHBondContact O-N 3.25Å
7	P	27.8	Very low	32.3	Very low	89 Å²	89	88.1 Å²	88.1	58%	0.578	60%	0.6	S	S	*	*	S	Bend	trans	-59.6	139.5	172.2	30.1	-32	0	0	0	106.9
8	D	30.4	Very low	32.2	Very low	145 Å²	145	95.9 Å²	95.9	78%	0.775	62%	0.615	S	S	*	*			trans	89.8	62.6	176.5	-43.6	-35	0	0	0	116.3	G6	G6-D8 PolarHBondContact O-N 3.25Å
9	A	31.1	Very low	32.2	Very low	93 Å²	93	102.8 Å²	102.8	77%	0.769	63%	0.628	S	S	*	*			trans	-114.5	79.3	141.7	0	0	0	0	0	108	P11	A9-P11 VanDerWaalsContact O-CD 3.28Å; A9-P11 WeakPolarHBondContact O-CD 3.22Å
10	G	25.2	Very low	32.1	Very low	78 Å²	78	103 Å²	103	80%	0.804	63%	0.631	S	S	*	*			trans	-76.9	122.4	158.5	0	0	0	0	0	108.6
11	P	31.4	Very low	32	Very low	109 Å²	109	104.9 Å²	104.9	71%	0.708	64%	0.637	S	S	*	*			trans	-106.7	107.9	159.2	19.3	2.2	0	0	0	107.3	A9 G13	A9-P11 VanDerWaalsContact O-CD 3.28Å; A9-P11 WeakPolarHBondContact O-CD 3.22Å; P11-G13 PolarHBondContact O-N 2.79Å
12	S	29	Very low	31.5	Very low	115 Å²	115	107.5 Å²	107.5	80%	0.804	67%	0.666	S	S	*	*				8.1	115.4	127.5	52.5	0	0	0	0	115.9
13	G	26.7	Very low	30.9	Very low	69 Å²	69	109.7 Å²	109.7	71%	0.711	69%	0.69	S	S	*	*			trans	80.1	130	132.6	0	0	0	0	0	118.5	P11	P11-G13 PolarHBondContact O-N 2.79Å
14	N	28.4	Very low	30.7	Very low	156 Å²	156	111.2 Å²	111.2	83%	0.834	72%	0.716	S	S	*	*			trans	84.6	95	152.2	-77.4	2.9	0	0	0	119.4
15	S	28.2	Very low	30.6	Very low	100 Å²	100	115.5 Å²	115.5	70%	0.699	75%	0.753	S	S	*	*				53.9	109.5	118.8	40.6	0	0	0	0	118.7
16	S	31.6	Very low	30.7	Very low	108 Å²	108	114.5 Å²	114.5	76%	0.755	75%	0.751	S	S	*	*				169.8	156.4	100.2	43.5	0	0	0	0	112.5
17	P	35.5	Very low	30.8	Very low	103 Å²	103	120.5 Å²	120.5	67%	0.669	78%	0.775	S	S	*	*			trans	-119.5	115.3	-154.7	33.8	-16.1	0	0	0	113.7
18	W	31.6	Very low	31.3	Very low	228 Å²	228	122.7 Å²	122.7	86%	0.864	79%	0.787	S	S	*	*			trans	-154.8	110.9	168.7	-55.7	93.3	0	0	0	106.7
19	W	31.2	Very low	31.5	Very low	228 Å²	228	121.2 Å²	121.2	86%	0.864	79%	0.788	S	S	*	*				-163.7	151	60.1	39.3	-94.7	0	0	0	111
20	P	31.6	Very low	31.6	Very low	105 Å²	105	128 Å²	128	68%	0.682	79%	0.793	S	S	*	*			trans	-105.2	169.6	172.5	38.9	-30.2	0	0	0	113
21	L	29.6	Very low	32.2	Very low	144 Å²	144	133.7 Å²	133.7	75%	0.754	80%	0.799	S	S	*	*			trans	93.4	103.5	160.9	-61	156.7	0	0	0	118.4
22	A	34.3	Very low	32.2	Very low	106 Å²	106	132.8 Å²	132.8	88%	0.876	80%	0.801	S	S	*	*				-144.5	91.8	126.7	0	0	0	0	0	108.8
23	T	31.7	Very low	32.3	Very low	133 Å²	133	136.7 Å²	136.7	82%	0.816	81%	0.806	S	S	*	*			trans	-71.4	116.9	163.1	41.7	0	0	0	0	109
24	G	35.1	Very low	32.8	Very low	77 Å²	77	137.9 Å²	137.9	79%	0.794	81%	0.81	S	S	*	*			trans	-137	98.4	167.7	0	0	0	0	0	108.9
25	A	31.6	Very low	33	Very low	112 Å²	112	139 Å²	139	93%	0.926	82%	0.815	S	S	*	*			trans	-66.7	139.6	174.5	0	0	0	0	0	110.9
26	G	34.2	Very low	33.1	Very low	70 Å²	70	137.7 Å²	137.7	72%	0.722	82%	0.816	S	S	*	*			trans	-171.9	95.6	173	0	0	0	0	0	111.2	T28	G26-T28 PolarHBondContact O-N 3.19Å
27	N	30.2	Very low	33	Very low	162 Å²	162	142.3 Å²	142.3	87%	0.866	83%	0.826	S	S	*	*			trans	-48.6	121.6	170.6	-87.5	-20	0	0	0	112.1
28	T	39.5	Very low	32.8	Very low	136 Å²	136	141 Å²	141	83%	0.834	83%	0.831	S	S	*	*			trans	-148.3	92.4	143.8	21.6	0	0	0	0	109.6	G26 R30	G26-T28 PolarHBondContact O-N 3.19Å; T28-R30 PolarHBondContact O-N 3.38Å
29	S	33.1	Very low	32.9	Very low	113 Å²	113	138.9 Å²	138.9	79%	0.79	84%	0.836	S	S	*	*			trans	-69.5	105.6	157.4	43.8	0	0	0	0	109.6
30	R	34	Very low	33.2	Very low	236 Å²	236	130.3 Å²	130.3	89%	0.891	82%	0.819	S	S	*	*			trans	-173.5	146.2	154.2	-104.4	167	-178.5	175.1	0.3	108.1	T28	T28-R30 PolarHBondContact O-N 3.38Å
31	E	38.4	Very low	33.7	Very low	198 Å²	198	130.1 Å²	130.1	93%	0.925	82%	0.818	S	S	*	*			trans	83.1	57.7	-175.7	-58.5	178.3	122.8	0	0	115.6
32	A	30.7	Very low	34.5	Very low	90 Å²	90	129.4 Å²	129.4	74%	0.744	82%	0.822	S	S	*	*			trans	-76.5	151.8	135.4	0	0	0	0	0	109
33	E	31.8	Very low	35.3	Very low	197 Å²	197	135 Å²	135	92%	0.921	82%	0.82	S	S	*	*			trans	86.5	75.8	169.4	-55.4	-171.5	123.2	0	0	118.1
34	A	36.3	Very low	36.6	Very low	94 Å²	94	133.4 Å²	133.4	78%	0.777	81%	0.807	S	S	*	*			trans	-145.4	92.9	142.6	0	0	0	0	0	109.9
35	L	33.3	Very low	38	Very low	180 Å²	180	134.9 Å²	134.9	94%	0.942	80%	0.8	S	S	*	*			trans	21.8	106.7	135.7	-60.2	158.8	0	0	0	114.4
36	G	29.4	Very low	40	Very low	71 Å²	71	132.6 Å²	132.6	73%	0.732	77%	0.768	S	S	*	*				82.4	71.9	69.6	0	0	0	0	0	111.3
37	E	30.1	Very low	42.2	Very low	206 Å²	206	133.3 Å²	133.3	96%	0.963	76%	0.755	S	S	*	*			trans	-171.1	127.8	156.4	-111.8	-177	119.6	0	0	111.8
38	G	32.1	Very low	44.8	Very low	74 Å²	74	129.8 Å²	129.8	76%	0.763	73%	0.733	S	S	*	*			trans	93.8	61.6	147.9	0	0	0	0	0	119.4	G40	G38-G40 PolarHBondContact O-N 3.24Å
39	N	32.3	Very low	47	Very low	184 Å²	184	129.2 Å²	129.2	98%	0.984	72%	0.721	S	S	*	*			trans	-72.2	64.4	160.6	-158.6	23.8	0	0	0	111.1
40	G	37.9	Very low	49.4	Very low	49 Å²	49	125.1 Å²	125.1	51%	0.505	69%	0.69	S	S	.	*			trans	-104.8	152	171.1	0	0	0	0	0	110.8	G38	G38-G40 PolarHBondContact O-N 3.24Å
41	P	41.6	Very low	51.9	Low	100 Å²	100	114.2 Å²	114.2	65%	0.649	65%	0.651	S	S	*	*	P	Polyproline II helix	trans	-58.3	149.3	177.1	26.6	-33.3	0	0	0	109.9	R43	P41-R43 PolarHBondContact O-N 2.92Å
42	P	47.5	Very low	54.3	Low	129 Å²	129	110.4 Å²	110.4	84%	0.838	63%	0.631	S	S	*	*	P	Polyproline II helix	trans	-54.5	116.2	-176.5	22.4	-31.1	0	0	0	108.4	D44	P42-D44 PolarHBondContact O-N 3.45Å
43	R	51.4	Low	57.1	Low	224 Å²	224	110.9 Å²	110.9	85%	0.845	62%	0.621	S	S	*	*	P	Polyproline II helix	trans	-58.8	137	169.3	-71.9	178.6	173.1	158.6	-1.4	106	P41 V45	P41-R43 PolarHBondContact O-N 2.92Å; R43-V45 HydrophobicContact CB-CG2 4.26Å; R43-V45 WeakPolarHBondContact O-CG2 3.43Å; R43-V45 PolarHBondContact O-N 3.03Å
44	D	59	Low	59.8	Low	99 Å²	99	102.3 Å²	102.3	53%	0.529	58%	0.58	S	S	.	*			trans	-63.4	79.2	174	-162.2	-3.3	0	0	0	107.3	P42 R46 Y115 R116	P42-D44 PolarHBondContact O-N 3.45Å; D44-R46 PolarHBondContact O-N 3.13Å; D44-Y115 WeakPolarHBondContact CB-OH 3.41Å; D44-Y115 PolarHBondContact O-OH 3.28Å; D44-Y115 VanDerWaalsContact O-OH 3.05Å; D44-Y115 PolarHBondContact OD1-OH 3.14Å; D44-Y115 PolarHBondContact OD2-OH 3.46Å; D44-Y115 VanDerWaalsContact OD2-OH 3.04Å; D44-R116 IonicContact OD2-CZ 3.36Å; D44-R116 IonicContact OD2-NH2 3.56Å; D44-R116 PolarHBondContact OD2-NH2 3.11Å
45	V	64.2	Low	62.4	Low	108 Å²	108	99.7 Å²	99.7	66%	0.655	55%	0.553	S	S	*	*			trans	-82.2	108.6	-173.3	179	0	0	0	0	107.7	R43	R43-V45 HydrophobicContact CB-CG2 4.26Å; R43-V45 WeakPolarHBondContact O-CG2 3.43Å; R43-V45 PolarHBondContact O-N 3.03Å
46	R	73.4	Confident	65.3	Low	65 Å²	65	93.7 Å²	93.7	25%	0.245	53%	0.529	C	S	.	.			trans	-77.1	133.6	170	176	175.5	69	172.2	0.3	110.5	D44 E48 A51 D112 Y115 E326	D44-R46 PolarHBondContact O-N 3.13Å; R46-E48 IonicContact CZ-OE1 2.93Å; R46-E48 VanDerWaalsContact CZ-OE1 3.27Å; R46-E48 IonicContact CZ-OE2 2.89Å; R46-E48 IonicContact NE-OE1 3.89Å; R46-E48 PolarHBondContact NE-OE1 3.19Å; R46-E48 IonicContact NE-OE2 2.81Å; R46-E48 VanDerWaalsContact NH2-CD 3.27Å; R46-E48 IonicContact NH2-OE1 3.26Å; R46-E48 PolarHBondContact NH2-OE1 3.41Å; R46-E48 IonicContact NH2-OE2 3.39Å; R46-E48 PolarHBondContact NH2-OE2 3.32Å; R46-E48 PolarHBondContact O-N 3.19Å; R46-A51 HydrophobicContact CG-CB 4.18Å; R46-D112 PolarHBondContact NH1-O 3.26Å; R46-Y115 HydrophobicContact CB-CD2 4.39Å; R46-Y115 HydrophobicContact CB-CE2 3.83Å; R46-Y115 HydrophobicContact CG-CE2 4.35Å; R46-E326 WeakPolarHBondContact CA-OE1 3.43Å
47	N	80.6	Confident	68.2	Low	84 Å²	84	92.5 Å²	92.5	45%	0.449	51%	0.508	S	S	.	.			trans	-67.7	94.2	163.8	-167	-18	0	0	0	111.5	E49 L50 A51 E326	N47-E49 VanDerWaalsContact C-N 3.3Å; N47-E49 PolarHBondContact O-N 3.07Å; N47-E49 PolarHBondContact OD1-N 3.3Å; N47-L50 HydrophobicContact CB-CB 4.12Å; N47-L50 PolarHBondContact O-N 3.05Å; N47-A51 PolarHBondContact O-N 3.03Å; N47-E326 PolarHBondContact N-OE1 2.84Å
48	E	84.1	Confident	71.2	Confident	89 Å²	89	83 Å²	83	42%	0.416	46%	0.464	S	S	.	.	H	α-helix	trans	-57.7	-37	-176.2	-75.5	-65.4	155.5	0	0	113.8	R46 A51 K52	R46-E48 IonicContact CZ-OE1 2.93Å; R46-E48 VanDerWaalsContact CZ-OE1 3.27Å; R46-E48 IonicContact CZ-OE2 2.89Å; R46-E48 IonicContact NE-OE1 3.89Å; R46-E48 PolarHBondContact NE-OE1 3.19Å; R46-E48 IonicContact NE-OE2 2.81Å; R46-E48 VanDerWaalsContact NH2-CD 3.27Å; R46-E48 IonicContact NH2-OE1 3.26Å; R46-E48 PolarHBondContact NH2-OE1 3.41Å; R46-E48 IonicContact NH2-OE2 3.39Å; R46-E48 PolarHBondContact NH2-OE2 3.32Å; R46-E48 PolarHBondContact O-N 3.19Å; E48-A51 PolarHBondContact O-N 3.04Å; E48-K52 VanDerWaalsContact O-CG 3.29Å; E48-K52 WeakPolarHBondContact O-CG 3.39Å; E48-K52 PolarHBondContact O-N 3.41Å
49	E	86.2	Confident	74.2	Confident	123 Å²	123	81.5 Å²	81.5	58%	0.575	44%	0.444	S	S	*	.	H	α-helix	trans	-69.7	-40.5	-179.2	-66.2	-56.4	119.6	0	0	111.4	N47 A51 K52 L53	N47-E49 VanDerWaalsContact C-N 3.3Å; N47-E49 PolarHBondContact O-N 3.07Å; N47-E49 PolarHBondContact OD1-N 3.3Å; E49-A51 VanDerWaalsContact C-N 3.34Å; E49-K52 PolarHBondContact O-N 3.13Å; E49-K52 IonicContact OE1-NZ 3.27Å; E49-K52 PolarHBondContact OE1-NZ 3.18Å; E49-L53 WeakPolarHBondContact O-CB 3.39Å; E49-L53 PolarHBondContact O-N 3.27Å; E49-L53 VanDerWaalsContact O-N 3.07Å
50	L	83.6	Confident	77.1	Confident	27 Å²	27	77.2 Å²	77.2	14%	0.141	42%	0.424	C	S	.	.	H	α-helix	trans	-64.7	-41	174	-176.4	60.4	0	0	0	111.1	N47 L53 E54 P328 T331	N47-L50 HydrophobicContact CB-CB 4.12Å; N47-L50 PolarHBondContact O-N 3.05Å; L50-L53 PolarHBondContact O-N 3.45Å; L50-E54 WeakPolarHBondContact O-CB 3.46Å; L50-E54 PolarHBondContact O-N 3.33Å; L50-P328 HydrophobicContact CD1-CB 4.13Å; L50-P328 HydrophobicContact CD2-CB 4.17Å; L50-T331 HydrophobicContact CD1-CG2 4.44Å
51	A	85.4	Confident	79.8	Confident	8 Å²	8	75 Å²	75	7%	0.066	40%	0.401	C	S	.	.	H	α-helix	trans	-64.5	-44.4	177.9	0	0	0	0	0	112.2	R46 N47 E48 E49 L53 E54 I55	R46-A51 HydrophobicContact CG-CB 4.18Å; N47-A51 PolarHBondContact O-N 3.03Å; E48-A51 PolarHBondContact O-N 3.04Å; E49-A51 VanDerWaalsContact C-N 3.34Å; A51-L53 VanDerWaalsContact C-N 3.32Å; A51-L53 PolarHBondContact O-N 3.01Å; A51-E54 PolarHBondContact O-N 3Å; A51-I55 WeakPolarHBondContact O-CB 3.48Å; A51-I55 WeakPolarHBondContact O-CD1 3.5Å; A51-I55 WeakPolarHBondContact O-CG1 3.45Å; A51-I55 PolarHBondContact O-N 3.24Å
52	K	90.4	Very high	82.3	Confident	117 Å²	117	72.2 Å²	72.2	51%	0.509	38%	0.379	S	S	.	.	H	α-helix	trans	-59.5	-43	174.8	-72.5	170.6	-167.5	166	0	111.7	E48 E49 A56	E48-K52 VanDerWaalsContact O-CG 3.29Å; E48-K52 WeakPolarHBondContact O-CG 3.39Å; E48-K52 PolarHBondContact O-N 3.41Å; E49-K52 PolarHBondContact O-N 3.13Å; E49-K52 IonicContact OE1-NZ 3.27Å; E49-K52 PolarHBondContact OE1-NZ 3.18Å; K52-A56 WeakPolarHBondContact O-CB 3.41Å; K52-A56 PolarHBondContact O-N 3.36Å
53	L	89.2	Confident	84.6	Confident	101 Å²	101	68.2 Å²	68.2	53%	0.529	36%	0.356	S	S	.	.	H	α-helix	trans	-63.9	-46.1	176.8	-179.3	65.2	0	0	0	111.5	E49 L50 A51 A56 V57	E49-L53 WeakPolarHBondContact O-CB 3.39Å; E49-L53 PolarHBondContact O-N 3.27Å; E49-L53 VanDerWaalsContact O-N 3.07Å; L50-L53 PolarHBondContact O-N 3.45Å; A51-L53 VanDerWaalsContact C-N 3.32Å; A51-L53 PolarHBondContact O-N 3.01Å; L53-A56 PolarHBondContact O-N 3.24Å; L53-V57 HydrophobicContact CD1-CG2 4.3Å; L53-V57 VanDerWaalsContact O-CG2 3.31Å; L53-V57 WeakPolarHBondContact O-CG2 3.3Å; L53-V57 PolarHBondContact O-N 3.5Å
54	E	88.3	Confident	86.7	Confident	16 Å²	16	60 Å²	60	8%	0.075	33%	0.331	C	S	.	.	H	α-helix	trans	-58.2	-48.9	176.6	-179.6	170	-159.7	0	0	111.1	L50 A51 A56 V57 L58 T331 L335	L50-E54 WeakPolarHBondContact O-CB 3.46Å; L50-E54 PolarHBondContact O-N 3.33Å; A51-E54 PolarHBondContact O-N 3Å; E54-A56 PolarHBondContact O-N 3.34Å; E54-V57 PolarHBondContact O-N 3.22Å; E54-L58 HydrophobicContact CG-CD1 3.79Å; E54-L58 HydrophobicContact CG-CG 4.35Å; E54-L58 WeakPolarHBondContact O-CB 3.49Å; E54-L58 VanDerWaalsContact O-CG 3.25Å; E54-L58 WeakPolarHBondContact O-CG 3.41Å; E54-L58 PolarHBondContact O-N 3.06Å; E54-T331 HydrophobicContact CB-CG2 4.06Å; E54-T331 HydrophobicContact CG-CG2 3.93Å; E54-L335 HydrophobicContact CG-CD2 4.38Å
55	I	91.7	Very high	88.3	Confident	40 Å²	40	55.3 Å²	55.3	21%	0.205	31%	0.306	C	S	.	.	H	α-helix	trans	-59.3	-45.9	177.4	-66.4	162	0	0	0	111	A51 L58 A59 D112 I113	A51-I55 WeakPolarHBondContact O-CB 3.48Å; A51-I55 WeakPolarHBondContact O-CD1 3.5Å; A51-I55 WeakPolarHBondContact O-CG1 3.45Å; A51-I55 PolarHBondContact O-N 3.24Å; I55-L58 PolarHBondContact O-N 3.29Å; I55-A59 VanDerWaalsContact O-CB 3.27Å; I55-A59 WeakPolarHBondContact O-CB 3.47Å; I55-A59 PolarHBondContact O-N 3.36Å; I55-D112 HydrophobicContact CD1-CB 4.41Å; I55-D112 HydrophobicContact CG1-CB 3.8Å; I55-I113 HydrophobicContact CD1-CG1 3.89Å; I55-I113 HydrophobicContact CG1-CG1 4.04Å; I55-I113 HydrophobicContact CG2-CD1 4.21Å; I55-I113 HydrophobicContact CG2-CG1 3.9Å
56	A	92.9	Very high	89.9	Confident	54 Å²	54	51.5 Å²	51.5	45%	0.446	28%	0.283	S	S	.	.	H	α-helix	trans	-61.6	-45.8	179.4	0	0	0	0	0	111.8	K52 L53 E54 A59 V60	K52-A56 WeakPolarHBondContact O-CB 3.41Å; K52-A56 PolarHBondContact O-N 3.36Å; L53-A56 PolarHBondContact O-N 3.24Å; E54-A56 PolarHBondContact O-N 3.34Å; A56-A59 PolarHBondContact O-N 3.27Å; A56-V60 WeakPolarHBondContact O-CG2 3.22Å; A56-V60 PolarHBondContact O-N 2.93Å
57	V	91.3	Very high	90.8	Very high	45 Å²	45	54.1 Å²	54.1	27%	0.273	30%	0.301	S	S	.	.	H	α-helix	trans	-67	-42.4	179.1	177.2	0	0	0	0	111.1	L53 E54 V60 T61 L335	L53-V57 HydrophobicContact CD1-CG2 4.3Å; L53-V57 VanDerWaalsContact O-CG2 3.31Å; L53-V57 WeakPolarHBondContact O-CG2 3.3Å; L53-V57 PolarHBondContact O-N 3.5Å; E54-V57 PolarHBondContact O-N 3.22Å; V57-V60 PolarHBondContact O-N 3.35Å; V57-T61 VanDerWaalsContact O-CB 3.26Å; V57-T61 WeakPolarHBondContact O-CB 3.35Å; V57-T61 PolarHBondContact O-N 2.84Å; V57-T61 PolarHBondContact O-OG1 3.01Å; V57-L335 HydrophobicContact CB-CD1 4.11Å; V57-L335 HydrophobicContact CB-CD2 4.12Å; V57-L335 HydrophobicContact CG1-CB 4.24Å; V57-L335 HydrophobicContact CG1-CD1 4.05Å; V57-L335 HydrophobicContact CG1-CD2 3.84Å; V57-L335 HydrophobicContact CG1-CG 4.26Å; V57-L335 HydrophobicContact CG2-CD1 4.4Å
58	L	92.1	Very high	91.4	Very high	8 Å²	8	50.9 Å²	50.9	4%	0.042	29%	0.288	C	S	.	.	H	α-helix	trans	-64	-39.8	176.6	-71	172.7	0	0	0	111.8	E54 I55 T61 F62 V105 Q108 M109 D112 L335	E54-L58 HydrophobicContact CG-CD1 3.79Å; E54-L58 HydrophobicContact CG-CG 4.35Å; E54-L58 WeakPolarHBondContact O-CB 3.49Å; E54-L58 VanDerWaalsContact O-CG 3.25Å; E54-L58 WeakPolarHBondContact O-CG 3.41Å; E54-L58 PolarHBondContact O-N 3.06Å; I55-L58 PolarHBondContact O-N 3.29Å; L58-T61 PolarHBondContact O-N 3.34Å; L58-F62 VanDerWaalsContact O-CB 3.23Å; L58-F62 WeakPolarHBondContact O-CB 3.31Å; L58-F62 PolarHBondContact O-N 3.2Å; L58-V105 HydrophobicContact CB-CG1 4.36Å; L58-V105 HydrophobicContact CD2-CG1 3.99Å; L58-Q108 HydrophobicContact CD1-CG 3.91Å; L58-M109 HydrophobicContact CB-CB 4.05Å; L58-M109 HydrophobicContact CB-CG 4.18Å; L58-M109 HydrophobicContact CD1-CB 4.24Å; L58-D112 WeakPolarHBondContact CD1-OD2 3.22Å; L58-L335 HydrophobicContact CD2-CD2 3.67Å; L58-L335 HydrophobicContact CG-CD2 3.74Å
59	A	95.1	Very high	91.9	Very high	41 Å²	41	46.7 Å²	46.7	34%	0.339	27%	0.268	S	S	.	.	H	α-helix	trans	-63.4	-46	176.9	0	0	0	0	0	111.9	I55 A56 F62 A63 M109	I55-A59 VanDerWaalsContact O-CB 3.27Å; I55-A59 WeakPolarHBondContact O-CB 3.47Å; I55-A59 PolarHBondContact O-N 3.36Å; A56-A59 PolarHBondContact O-N 3.27Å; A59-F62 PolarHBondContact O-N 3.39Å; A59-A63 WeakPolarHBondContact O-CB 3.33Å; A59-A63 PolarHBondContact O-N 3.28Å; A59-M109 VanDerWaalsContact CA-SD 3.59Å; A59-M109 HydrophobicContact CB-SD 3.76Å
60	V	94.3	Very high	92.2	Very high	94 Å²	94	43.2 Å²	43.2	57%	0.57	26%	0.258	S	S	*	.	H	α-helix	trans	-63.4	-46.2	175.5	172.9	0	0	0	0	110.7	A56 V57 F62 A63 V64	A56-V60 WeakPolarHBondContact O-CG2 3.22Å; A56-V60 PolarHBondContact O-N 2.93Å; V57-V60 PolarHBondContact O-N 3.35Å; V60-F62 VanDerWaalsContact C-N 3.35Å; V60-F62 PolarHBondContact O-N 3.14Å; V60-A63 PolarHBondContact O-N 3.22Å; V60-V64 HydrophobicContact CG1-CG2 4.27Å; V60-V64 WeakPolarHBondContact O-CB 3.09Å; V60-V64 VanDerWaalsContact O-CG2 3.3Å; V60-V64 WeakPolarHBondContact O-CG2 3.25Å; V60-V64 PolarHBondContact O-N 3.05Å
61	T	92.8	Very high	92.6	Very high	4 Å²	4	43.4 Å²	43.4	3%	0.025	26%	0.261	C	S	.	.	H	α-helix	trans	-59.8	-45.6	178.5	-59.8	0	0	0	0	111	V57 L58 V64 A65 C342	V57-T61 VanDerWaalsContact O-CB 3.26Å; V57-T61 WeakPolarHBondContact O-CB 3.35Å; V57-T61 PolarHBondContact O-N 2.84Å; V57-T61 PolarHBondContact O-OG1 3.01Å; L58-T61 PolarHBondContact O-N 3.34Å; T61-V64 PolarHBondContact O-N 2.88Å; T61-A65 WeakPolarHBondContact O-CB 3.31Å; T61-A65 PolarHBondContact O-N 2.93Å; T61-C342 PolarHBondContact O-SG 2.87Å; T61-C342 VanDerWaalsContact O-SG 3.4Å
62	F	95.1	Very high	92.8	Very high	41 Å²	41	43.6 Å²	43.6	18%	0.18	26%	0.261	C	S	.	.	H	α-helix	trans	-59.1	-50.8	176.3	177.9	-103.4	0	0	0	111.4	L58 A59 V60 V64 A65 V66 A101 F102 V105 L106	L58-F62 VanDerWaalsContact O-CB 3.23Å; L58-F62 WeakPolarHBondContact O-CB 3.31Å; L58-F62 PolarHBondContact O-N 3.2Å; A59-F62 PolarHBondContact O-N 3.39Å; V60-F62 VanDerWaalsContact C-N 3.35Å; V60-F62 PolarHBondContact O-N 3.14Å; F62-V64 PolarHBondContact O-N 3.43Å; F62-A65 PolarHBondContact O-N 3.38Å; F62-V66 HydrophobicContact CD2-CG2 4.05Å; F62-V66 HydrophobicContact CE1-CG2 4.21Å; F62-V66 HydrophobicContact CE2-CG2 3.69Å; F62-V66 HydrophobicContact CG-CG2 4.45Å; F62-V66 HydrophobicContact CZ-CG2 3.79Å; F62-V66 WeakPolarHBondContact O-CB 3.24Å; F62-V66 VanDerWaalsContact O-CG2 3.3Å; F62-V66 WeakPolarHBondContact O-CG2 3.48Å; F62-V66 PolarHBondContact O-N 3.42Å; F62-A101 HydrophobicContact CD2-CB 4.14Å; F62-A101 WeakPolarHBondContact CD2-O 3.21Å; F62-A101 HydrophobicContact CE2-CB 4.33Å; F62-A101 WeakPolarHBondContact CE2-O 3.48Å; F62-F102 HydrophobicContact CE2-CD1 4.18Å; F62-F102 HydrophobicContact CE2-CE1 4.31Å; F62-F102 HydrophobicContact CE2-CG 4.49Å; F62-F102 HydrophobicContact CZ-CD1 4.21Å; F62-F102 AromaticContact CZ-CE1 3.93Å; F62-F102 HydrophobicContact CZ-CE1 3.93Å; F62-F102 HydrophobicContact CZ-CZ 4.39Å; F62-V105 HydrophobicContact CB-CG1 3.92Å; F62-L106 HydrophobicContact CD2-CB 4.01Å; F62-L106 HydrophobicContact CE2-CB 3.74Å; F62-L106 HydrophobicContact CE2-CD2 4.29Å; F62-L106 HydrophobicContact CE2-CG 4.43Å; F62-L106 HydrophobicContact CZ-CB 4.39Å; F62-L106 HydrophobicContact CZ-CD1 4.49Å; F62-L106 HydrophobicContact CZ-CD2 4.26Å
63	A	95.9	Very high	92.9	Very high	44 Å²	44	39.7 Å²	39.7	36%	0.364	25%	0.246	S	C	.	.	H	α-helix	trans	-59.8	-48.3	179.5	0	0	0	0	0	111.8	A59 V60 V66 L67	A59-A63 WeakPolarHBondContact O-CB 3.33Å; A59-A63 PolarHBondContact O-N 3.28Å; V60-A63 PolarHBondContact O-N 3.22Å; A63-V66 PolarHBondContact O-N 3.29Å; A63-L67 VanDerWaalsContact O-CB 3.27Å; A63-L67 WeakPolarHBondContact O-CB 3.36Å; A63-L67 WeakPolarHBondContact O-CG 3.34Å; A63-L67 PolarHBondContact O-N 3.31Å
64	V	94.5	Very high	92.9	Very high	52 Å²	52	38.1 Å²	38.1	32%	0.315	24%	0.237	S	C	.	.	H	α-helix	trans	-64.4	-43.5	179.3	174.4	0	0	0	0	111.3	V60 T61 F62 G68 C342	V60-V64 HydrophobicContact CG1-CG2 4.27Å; V60-V64 WeakPolarHBondContact O-CB 3.09Å; V60-V64 VanDerWaalsContact O-CG2 3.3Å; V60-V64 WeakPolarHBondContact O-CG2 3.25Å; V60-V64 PolarHBondContact O-N 3.05Å; T61-V64 PolarHBondContact O-N 2.88Å; F62-V64 PolarHBondContact O-N 3.43Å; V64-G68 PolarHBondContact O-N 3.21Å; V64-C342 HydrophobicContact CG1-CB 3.77Å
65	A	94.4	Very high	92.9	Very high	1 Å²	1	37.4 Å²	37.4	1%	0.008	23%	0.234	C	C	.	.	H	α-helix	trans	-64.2	-45.4	179.1	0	0	0	0	0	111.8	T61 F62 N69 A101	T61-A65 WeakPolarHBondContact O-CB 3.31Å; T61-A65 PolarHBondContact O-N 2.93Å; F62-A65 PolarHBondContact O-N 3.38Å; A65-N69 VanDerWaalsContact O-CB 3.3Å; A65-N69 WeakPolarHBondContact O-CB 3.34Å; A65-N69 PolarHBondContact O-N 2.77Å; A65-N69 PolarHBondContact O-ND2 3.44Å; A65-A101 HydrophobicContact CB-CB 4.05Å
66	V	95.8	Very high	92.6	Very high	27 Å²	27	35.8 Å²	35.8	16%	0.164	23%	0.226	C	C	.	.	H	α-helix	trans	-66.5	-51.5	179.1	171.9	0	0	0	0	110.9	F62 A63 S70 L98 A101 F102	F62-V66 HydrophobicContact CD2-CG2 4.05Å; F62-V66 HydrophobicContact CE1-CG2 4.21Å; F62-V66 HydrophobicContact CE2-CG2 3.69Å; F62-V66 HydrophobicContact CG-CG2 4.45Å; F62-V66 HydrophobicContact CZ-CG2 3.79Å; F62-V66 WeakPolarHBondContact O-CB 3.24Å; F62-V66 VanDerWaalsContact O-CG2 3.3Å; F62-V66 WeakPolarHBondContact O-CG2 3.48Å; F62-V66 PolarHBondContact O-N 3.42Å; A63-V66 PolarHBondContact O-N 3.29Å; V66-S70 WeakPolarHBondContact O-CB 3.4Å; V66-S70 PolarHBondContact O-N 2.95Å; V66-S70 PolarHBondContact O-OG 2.91Å; V66-L98 HydrophobicContact CB-CD2 4.49Å; V66-L98 HydrophobicContact CG2-CD2 4.41Å; V66-A101 HydrophobicContact CG2-CB 3.93Å; V66-F102 HydrophobicContact CG1-CE2 4.47Å; V66-F102 HydrophobicContact CG1-CZ 4.4Å; V66-F102 HydrophobicContact CG2-CE2 3.98Å; V66-F102 HydrophobicContact CG2-CZ 4.16Å
67	L	94.1	Very high	92.3	Very high	120 Å²	120	40.6 Å²	40.6	63%	0.628	24%	0.239	S	C	*	.	H	α-helix	trans	-62.4	-46.9	-178.8	-69.4	173.4	0	0	0	111.3	A63 S71	A63-L67 VanDerWaalsContact O-CB 3.27Å; A63-L67 WeakPolarHBondContact O-CB 3.36Å; A63-L67 WeakPolarHBondContact O-CG 3.34Å; A63-L67 PolarHBondContact O-N 3.31Å; L67-S71 VanDerWaalsContact O-CB 3.25Å; L67-S71 WeakPolarHBondContact O-CB 3.37Å; L67-S71 PolarHBondContact O-N 3.37Å; L67-S71 PolarHBondContact O-OG 3Å
68	G	92.9	Very high	92	Very high	17 Å²	17	43.7 Å²	43.7	18%	0.175	25%	0.246	C	C	.	.	H	α-helix	trans	-64.2	-51.6	-178.4	0	0	0	0	0	112.5	V64 S71 V72	V64-G68 PolarHBondContact O-N 3.21Å; G68-S71 PolarHBondContact O-N 3.4Å; G68-V72 WeakPolarHBondContact O-CG2 3.31Å; G68-V72 PolarHBondContact O-N 3.29Å
69	N	93.8	Very high	91.3	Very high	0 Å²	0	44.8 Å²	44.8	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-70.8	-34.8	-178	-72	-67.8	0	0	0	112.5	A65 S71 V72 L73 S94 L98 S341	A65-N69 VanDerWaalsContact O-CB 3.3Å; A65-N69 WeakPolarHBondContact O-CB 3.34Å; A65-N69 PolarHBondContact O-N 2.77Å; A65-N69 PolarHBondContact O-ND2 3.44Å; N69-S71 VanDerWaalsContact C-N 3.34Å; N69-V72 PolarHBondContact O-N 2.93Å; N69-L73 WeakPolarHBondContact O-CG 3.29Å; N69-L73 PolarHBondContact O-N 3.48Å; N69-S94 PolarHBondContact OD1-OG 3.16Å; N69-L98 HydrophobicContact CB-CD2 3.94Å; N69-L98 HydrophobicContact CB-CG 3.85Å; N69-S341 PolarHBondContact ND2-O 2.8Å; N69-S341 VanDerWaalsContact ND2-O 3.14Å
70	S	93.5	Very high	89.7	Confident	51 Å²	51	48.7 Å²	48.7	36%	0.357	28%	0.275	S	S	.	.	H	α-helix	trans	-65.2	-39	173	-56.9	0	0	0	0	111.7	V66 L73 L74	V66-S70 WeakPolarHBondContact O-CB 3.4Å; V66-S70 PolarHBondContact O-N 2.95Å; V66-S70 PolarHBondContact O-OG 2.91Å; S70-L73 PolarHBondContact O-N 3.25Å; S70-L74 WeakPolarHBondContact O-CB 3.24Å; S70-L74 PolarHBondContact O-N 3.27Å
71	S	90.7	Very high	87.9	Confident	30 Å²	30	54.8 Å²	54.8	21%	0.21	29%	0.287	C	S	.	.	H	α-helix	trans	-63.4	-41	175.7	-60.2	0	0	0	0	111.9	L67 G68 N69 L74 A75	L67-S71 VanDerWaalsContact O-CB 3.25Å; L67-S71 WeakPolarHBondContact O-CB 3.37Å; L67-S71 PolarHBondContact O-N 3.37Å; L67-S71 PolarHBondContact O-OG 3Å; G68-S71 PolarHBondContact O-N 3.4Å; N69-S71 VanDerWaalsContact C-N 3.34Å; S71-L74 PolarHBondContact O-N 3.01Å; S71-A75 WeakPolarHBondContact O-CB 3.46Å; S71-A75 PolarHBondContact O-N 2.93Å
72	V	90.9	Very high	86.2	Confident	12 Å²	12	64.2 Å²	64.2	7%	0.073	33%	0.328	C	S	.	.	H	α-helix	trans	-62.7	-45.9	174.3	173.1	0	0	0	0	111	G68 N69 L74 A75 L76 I90 S94 P345 Y348	G68-V72 WeakPolarHBondContact O-CG2 3.31Å; G68-V72 PolarHBondContact O-N 3.29Å; N69-V72 PolarHBondContact O-N 2.93Å; V72-L74 VanDerWaalsContact C-N 3.34Å; V72-L74 PolarHBondContact O-N 3.34Å; V72-A75 PolarHBondContact O-N 3.23Å; V72-L76 HydrophobicContact CG1-CD1 3.99Å; V72-L76 HydrophobicContact CG1-CG 4.41Å; V72-L76 WeakPolarHBondContact O-CB 3.45Å; V72-L76 VanDerWaalsContact O-CG 3.25Å; V72-L76 WeakPolarHBondContact O-CG 3.41Å; V72-L76 PolarHBondContact O-N 2.95Å; V72-I90 HydrophobicContact CG1-CG2 3.62Å; V72-S94 WeakPolarHBondContact CG1-OG 3.32Å; V72-P345 HydrophobicContact CG2-CB 3.94Å; V72-P345 HydrophobicContact CG2-CG 4.35Å; V72-Y348 HydrophobicContact CG1-CD2 4.09Å; V72-Y348 HydrophobicContact CG2-CD2 4.03Å
73	L	91.6	Very high	84.6	Confident	35 Å²	35	67.5 Å²	67.5	18%	0.183	35%	0.352	C	S	.	.	H	α-helix	trans	-61.5	-42.4	176.9	-71.9	174.8	0	0	0	112.1	N69 S70 L76 H77 R91 L95 L98	N69-L73 WeakPolarHBondContact O-CG 3.29Å; N69-L73 PolarHBondContact O-N 3.48Å; S70-L73 PolarHBondContact O-N 3.25Å; L73-L76 PolarHBondContact O-N 2.81Å; L73-H77 WeakPolarHBondContact O-CB 3.01Å; L73-H77 PolarHBondContact O-N 3.46Å; L73-R91 HydrophobicContact CD2-CB 4.31Å; L73-R91 HydrophobicContact CD2-CG 3.7Å; L73-L95 HydrophobicContact CD1-CD2 3.95Å; L73-L95 HydrophobicContact CD1-CG 4.43Å; L73-L95 HydrophobicContact CD2-CG 4.35Å; L73-L98 HydrophobicContact CD1-CD1 3.48Å; L73-L98 VanDerWaalsContact CD1-CD1 3.48Å
74	L	90	Very high	83.6	Confident	68 Å²	68	68.2 Å²	68.2	36%	0.356	35%	0.354	S	S	.	.	H	α-helix	trans	-64	-46.1	177.2	-177.6	60.3	0	0	0	111.7	S70 S71 V72 L76 H77 R78	S70-L74 WeakPolarHBondContact O-CB 3.24Å; S70-L74 PolarHBondContact O-N 3.27Å; S71-L74 PolarHBondContact O-N 3.01Å; V72-L74 VanDerWaalsContact C-N 3.34Å; V72-L74 PolarHBondContact O-N 3.34Å; L74-L76 PolarHBondContact O-N 2.89Å; L74-H77 PolarHBondContact O-N 3.44Å; L74-R78 HydrophobicContact CD1-CG 4.37Å; L74-R78 WeakPolarHBondContact O-CB 3.28Å; L74-R78 WeakPolarHBondContact O-CG 3.25Å; L74-R78 PolarHBondContact O-N 3.43Å
75	A	86.6	Confident	83	Confident	1 Å²	1	68.7 Å²	68.7	1%	0.008	35%	0.35	C	S	.	.	H	α-helix	trans	-58.4	-49.1	175.4	0	0	0	0	0	110.8	S71 V72 H77 R78 T79 D358 C359	S71-A75 WeakPolarHBondContact O-CB 3.46Å; S71-A75 PolarHBondContact O-N 2.93Å; V72-A75 PolarHBondContact O-N 3.23Å; A75-H77 VanDerWaalsContact C-N 3.27Å; A75-H77 PolarHBondContact O-N 3.35Å; A75-R78 PolarHBondContact O-N 3.48Å; A75-R78 VanDerWaalsContact O-N 3.09Å; A75-T79 PolarHBondContact O-N 3.22Å; A75-T79 PolarHBondContact O-OG1 2.97Å; A75-D358 HydrophobicContact CB-CB 4.17Å; A75-C359 HydrophobicContact CB-CB 4.39Å
76	L	87	Confident	82.5	Confident	6 Å²	6	69.2 Å²	69.2	3%	0.031	35%	0.352	C	S	.	.	H	α-helix	trans	-63.8	-28.9	177.6	-70.9	175.4	0	0	0	114	V72 L73 L74 H87 I90 R91 L355	V72-L76 HydrophobicContact CG1-CD1 3.99Å; V72-L76 HydrophobicContact CG1-CG 4.41Å; V72-L76 WeakPolarHBondContact O-CB 3.45Å; V72-L76 VanDerWaalsContact O-CG 3.25Å; V72-L76 WeakPolarHBondContact O-CG 3.41Å; V72-L76 PolarHBondContact O-N 2.95Å; L73-L76 PolarHBondContact O-N 2.81Å; L74-L76 PolarHBondContact O-N 2.89Å; L76-H87 HydrophobicContact CD2-CB 3.89Å; L76-I90 HydrophobicContact CD1-CB 4.07Å; L76-I90 HydrophobicContact CD1-CG2 3.72Å; L76-R91 HydrophobicContact CD1-CB 4.22Å; L76-L355 HydrophobicContact CD2-CD1 4.34Å; L76-L355 HydrophobicContact CD2-CD2 3.68Å; L76-L355 HydrophobicContact CG-CD2 4.38Å
77	H	86.6	Confident	82	Confident	156 Å²	156	69 Å²	69	72%	0.722	35%	0.35	S	S	*	.	H	α-helix	trans	-74.8	-36.1	174.2	-174.6	-85.5	0	0	0	111.4	L73 L74 A75	L73-H77 WeakPolarHBondContact O-CB 3.01Å; L73-H77 PolarHBondContact O-N 3.46Å; L74-H77 PolarHBondContact O-N 3.44Å; A75-H77 VanDerWaalsContact C-N 3.27Å; A75-H77 PolarHBondContact O-N 3.35Å
78	R	84.6	Confident	81.8	Confident	110 Å²	110	65.2 Å²	65.2	42%	0.415	33%	0.33	S	S	.	.	H	α-helix	trans	-81.7	-22.7	-178.9	-73.8	-173.6	175.9	150.3	-2	114.3	L74 A75 P80 S362	L74-R78 HydrophobicContact CD1-CG 4.37Å; L74-R78 WeakPolarHBondContact O-CB 3.28Å; L74-R78 WeakPolarHBondContact O-CG 3.25Å; L74-R78 PolarHBondContact O-N 3.43Å; A75-R78 PolarHBondContact O-N 3.48Å; A75-R78 VanDerWaalsContact O-N 3.09Å; R78-P80 WeakPolarHBondContact O-CD 3.37Å; R78-P80 WeakPolarHBondContact O-CG 3.49Å; R78-P80 VanDerWaalsContact O-N 3.1Å; R78-S362 PolarHBondContact NH1-O 2.95Å; R78-S362 PolarHBondContact NH1-OG 3.49Å
79	T	77.4	Confident	81.8	Confident	30 Å²	30	64.6 Å²	64.6	18%	0.184	32%	0.322	C	S	.	.			trans	-63.7	105.1	179	-51.7	0	0	0	0	111.3	A75 R81 D358	A75-T79 PolarHBondContact O-N 3.22Å; A75-T79 PolarHBondContact O-OG1 2.97Å; T79-R81 VanDerWaalsContact C-N 3.32Å; T79-R81 PolarHBondContact O-N 2.87Å; T79-R81 VanDerWaalsContact O-N 3.1Å; T79-D358 PolarHBondContact OG1-OD2 3.48Å
80	P	62.1	Low	81.7	Confident	123 Å²	123	64.6 Å²	64.6	80%	0.799	32%	0.322	S	S	*	.			trans	-80.6	12.2	-165.2	-12	28.4	0	0	0	116.5	R78	R78-P80 WeakPolarHBondContact O-CD 3.37Å; R78-P80 WeakPolarHBondContact O-CG 3.49Å; R78-P80 VanDerWaalsContact O-N 3.1Å
81	R	55.6	Low	81.6	Confident	222 Å²	222	66.1 Å²	66.1	84%	0.838	32%	0.32	S	S	*	.	S	Bend	trans	-142	118.5	-169.4	-73.4	-177.4	172	160.2	-3.3	113.5	T79	T79-R81 VanDerWaalsContact C-N 3.32Å; T79-R81 PolarHBondContact O-N 2.87Å; T79-R81 VanDerWaalsContact O-N 3.1Å
82	K	56.3	Low	81.8	Confident	203 Å²	203	67 Å²	67	88%	0.883	32%	0.321	S	S	*	.			trans	39.9	96.4	176.3	-68.4	-172.4	179.3	-179.1	0	114.2	S84	K82-S84 PolarHBondContact O-N 3.21Å
83	T	62.5	Low	82	Confident	110 Å²	110	66.5 Å²	66.5	68%	0.675	32%	0.318	S	S	*	.			trans	-53.3	100.1	169.3	46.5	0	0	0	0	110
84	S	74.6	Confident	82.1	Confident	59 Å²	59	64.8 Å²	64.8	41%	0.413	31%	0.309	S	S	.	.			trans	-61.6	147.6	172.9	176.6	0	0	0	0	108.2	K82 M86 H87 L88	K82-S84 PolarHBondContact O-N 3.21Å; S84-M86 PolarHBondContact O-N 3.45Å; S84-M86 PolarHBondContact OG-N 3.1Å; S84-H87 WeakPolarHBondContact O-CA 3.36Å; S84-H87 VanDerWaalsContact O-CB 3.32Å; S84-H87 WeakPolarHBondContact O-CB 3.47Å; S84-H87 PolarHBondContact O-N 2.92Å; S84-L88 PolarHBondContact O-N 3.34Å
85	R	82.5	Confident	82.4	Confident	62 Å²	62	65 Å²	65	23%	0.234	31%	0.31	C	S	.	.	H	α-helix	trans	-52	-31.4	171.5	-156.9	-168.2	-38.1	163	-1.4	111.8	L88 F89 D148 S167	R85-L88 WeakPolarHBondContact O-CB 3.42Å; R85-L88 PolarHBondContact O-N 2.87Å; R85-F89 HydrophobicContact CG-CE2 4.38Å; R85-F89 VanDerWaalsContact O-CD2 3.31Å; R85-F89 WeakPolarHBondContact O-CD2 3.44Å; R85-F89 PolarHBondContact O-N 3.48Å; R85-D148 IonicContact NH1-OD1 3.21Å; R85-D148 PolarHBondContact NH1-OD1 3.43Å; R85-D148 IonicContact NH1-OD2 3.88Å; R85-S167 WeakPolarHBondContact CD-OG 3.35Å; R85-S167 VanDerWaalsContact CG-OG 3.28Å; R85-S167 WeakPolarHBondContact CG-OG 3.48Å
86	M	83.1	Confident	82.9	Confident	11 Å²	11	65 Å²	65	5%	0.054	31%	0.31	C	S	.	.	H	α-helix	trans	-65.4	-41.3	173.7	-176	57.3	91.6	0	0	112.4	S84 L88 F89 I90 R149 T289 M292 T293	S84-M86 PolarHBondContact O-N 3.45Å; S84-M86 PolarHBondContact OG-N 3.1Å; M86-L88 PolarHBondContact O-N 3.36Å; M86-F89 PolarHBondContact O-N 3.35Å; M86-F89 VanDerWaalsContact O-N 3.1Å; M86-I90 HydrophobicContact CG-CD1 3.77Å; M86-I90 HydrophobicContact CG-CG1 4.15Å; M86-I90 WeakPolarHBondContact O-CG1 3.42Å; M86-I90 PolarHBondContact O-N 3.5Å; M86-I90 HydrophobicContact SD-CD1 4.38Å; M86-I90 HydrophobicContact SD-CG1 4.2Å; M86-R149 VanDerWaalsContact CE-NH1 3.31Å; M86-T289 VanDerWaalsContact CE-CB 3.44Å; M86-T289 HydrophobicContact CE-CG2 3.63Å; M86-M292 HydrophobicContact CE-CE 3.9Å; M86-M292 HydrophobicContact CG-CE 4.39Å; M86-M292 HydrophobicContact SD-CE 3.91Å; M86-T293 HydrophobicContact CE-CG2 4.25Å
87	H	86.6	Confident	83.3	Confident	24 Å²	24	64.7 Å²	64.7	11%	0.111	31%	0.308	C	S	.	.	H	α-helix	trans	-61.1	-32.4	178	-64.6	-177.1	0	0	0	111.4	L76 S84 R91 H354	L76-H87 HydrophobicContact CD2-CB 3.89Å; S84-H87 WeakPolarHBondContact O-CA 3.36Å; S84-H87 VanDerWaalsContact O-CB 3.32Å; S84-H87 WeakPolarHBondContact O-CB 3.47Å; S84-H87 PolarHBondContact O-N 2.92Å; H87-R91 VanDerWaalsContact O-CB 3.28Å; H87-R91 WeakPolarHBondContact O-CB 3.5Å; H87-R91 PolarHBondContact O-N 3.1Å; H87-H354 AromaticContact CE1-CE1 3.99Å; H87-H354 AromaticContact CE1-NE2 3.47Å; H87-H354 PolarHBondContact CE1-NE2 3.48Å; H87-H354 AromaticContact NE2-CE1 3.49Å; H87-H354 PolarHBondContact NE2-CE1 2.81Å; H87-H354 AromaticContact NE2-NE2 3.41Å; H87-H354 PolarHBondContact NE2-NE2 3.08Å
88	L	90	Very high	83.7	Confident	40 Å²	40	58.3 Å²	58.3	21%	0.209	28%	0.28	C	S	.	.	H	α-helix	trans	-64.6	-47.1	173.4	-176	65.5	0	0	0	111.8	S84 R85 M86 R91 H92 R168 I171	S84-L88 PolarHBondContact O-N 3.34Å; R85-L88 WeakPolarHBondContact O-CB 3.42Å; R85-L88 PolarHBondContact O-N 2.87Å; M86-L88 PolarHBondContact O-N 3.36Å; L88-R91 PolarHBondContact O-N 3.48Å; L88-H92 PolarHBondContact O-CD2 2.9Å; L88-H92 PolarHBondContact O-N 3.46Å; L88-H92 VanDerWaalsContact O-N 3.12Å; L88-R168 HydrophobicContact CD2-CG 3.92Å; L88-I171 HydrophobicContact CD2-CD1 3.83Å; L88-I171 HydrophobicContact CG-CD1 3.71Å
89	F	91.6	Very high	84.2	Confident	3 Å²	3	53.6 Å²	53.6	1%	0.013	26%	0.264	C	S	.	.	H	α-helix	trans	-63.5	-45.5	176.4	-77	-70.6	0	0	0	112.2	R85 M86 R91 H92 L93 V144 M145 D148 S167 I171	R85-F89 HydrophobicContact CG-CE2 4.38Å; R85-F89 VanDerWaalsContact O-CD2 3.31Å; R85-F89 WeakPolarHBondContact O-CD2 3.44Å; R85-F89 PolarHBondContact O-N 3.48Å; M86-F89 PolarHBondContact O-N 3.35Å; M86-F89 VanDerWaalsContact O-N 3.1Å; F89-R91 VanDerWaalsContact C-N 3.28Å; F89-R91 PolarHBondContact O-N 3.07Å; F89-H92 PolarHBondContact O-N 2.95Å; F89-L93 WeakPolarHBondContact O-CB 3.22Å; F89-L93 PolarHBondContact O-N 3.49Å; F89-V144 HydrophobicContact CD1-CG2 4.39Å; F89-V144 HydrophobicContact CE1-CB 4.35Å; F89-V144 HydrophobicContact CE1-CG2 3.95Å; F89-M145 HydrophobicContact CB-CB 4.47Å; F89-M145 HydrophobicContact CB-CG 4.2Å; F89-M145 HydrophobicContact CB-SD 4.42Å; F89-M145 HydrophobicContact CD1-CB 4.09Å; F89-M145 HydrophobicContact CG-CB 4.36Å; F89-M145 HydrophobicContact CG-CG 4.38Å; F89-D148 HydrophobicContact CE2-CB 3.59Å; F89-D148 VanDerWaalsContact CE2-CG 3.5Å; F89-D148 HydrophobicContact CZ-CB 3.59Å; F89-S167 WeakPolarHBondContact CE2-OG 3.38Å; F89-I171 HydrophobicContact CD1-CD1 3.98Å; F89-I171 HydrophobicContact CD1-CG1 3.98Å; F89-I171 HydrophobicContact CE1-CD1 3.97Å; F89-I171 HydrophobicContact CE1-CG1 3.73Å
90	I	91	Very high	85	Confident	0 Å²	0	52.4 Å²	52.4	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-59.2	-42.8	177.7	-62.9	172.2	0	0	0	110.1	V72 L76 M86 H92 L93 S94 M292 Y348 L355	V72-I90 HydrophobicContact CG1-CG2 3.62Å; L76-I90 HydrophobicContact CD1-CB 4.07Å; L76-I90 HydrophobicContact CD1-CG2 3.72Å; M86-I90 HydrophobicContact CG-CD1 3.77Å; M86-I90 HydrophobicContact CG-CG1 4.15Å; M86-I90 WeakPolarHBondContact O-CG1 3.42Å; M86-I90 PolarHBondContact O-N 3.5Å; M86-I90 HydrophobicContact SD-CD1 4.38Å; M86-I90 HydrophobicContact SD-CG1 4.2Å; I90-H92 PolarHBondContact O-N 3.36Å; I90-L93 PolarHBondContact O-N 2.95Å; I90-S94 WeakPolarHBondContact O-CB 3.31Å; I90-S94 PolarHBondContact O-N 2.91Å; I90-S94 PolarHBondContact O-OG 2.95Å; I90-M292 HydrophobicContact CD1-CE 4.22Å; I90-M292 HydrophobicContact CG1-CE 4.47Å; I90-Y348 HydrophobicContact CB-CE1 4.48Å; I90-Y348 HydrophobicContact CD1-CD1 4.05Å; I90-Y348 HydrophobicContact CD1-CE1 4.21Å; I90-Y348 HydrophobicContact CG1-CD1 4.15Å; I90-Y348 HydrophobicContact CG1-CE1 3.81Å; I90-Y348 HydrophobicContact CG2-CD1 4.18Å; I90-Y348 HydrophobicContact CG2-CD2 3.98Å; I90-Y348 HydrophobicContact CG2-CE1 4.04Å; I90-Y348 HydrophobicContact CG2-CE2 3.84Å; I90-Y348 HydrophobicContact CG2-CG 4.17Å; I90-L355 HydrophobicContact CD1-CD1 4.41Å
91	R	92.7	Very high	86.6	Confident	84 Å²	84	46.5 Å²	46.5	32%	0.317	22%	0.218	S	C	.	.	H	α-helix	trans	-58.1	-50.4	176.3	-178.3	-177.9	-63.2	172	-1.7	112.1	L73 L76 H87 L88 F89 L93 S94 L95	L73-R91 HydrophobicContact CD2-CB 4.31Å; L73-R91 HydrophobicContact CD2-CG 3.7Å; L76-R91 HydrophobicContact CD1-CB 4.22Å; H87-R91 VanDerWaalsContact O-CB 3.28Å; H87-R91 WeakPolarHBondContact O-CB 3.5Å; H87-R91 PolarHBondContact O-N 3.1Å; L88-R91 PolarHBondContact O-N 3.48Å; F89-R91 VanDerWaalsContact C-N 3.28Å; F89-R91 PolarHBondContact O-N 3.07Å; R91-L93 VanDerWaalsContact C-N 3.35Å; R91-S94 PolarHBondContact O-N 3.17Å; R91-L95 HydrophobicContact CG-CD1 4.38Å; R91-L95 WeakPolarHBondContact O-CG 3.45Å; R91-L95 PolarHBondContact O-N 3.31Å
92	H	95.3	Very high	88.5	Confident	47 Å²	47	40.3 Å²	40.3	22%	0.218	20%	0.198	C	C	.	.	H	α-helix	trans	-70.4	-31.2	-178.8	-79.9	-81.7	0	0	0	113.2	L88 F89 I90 L95 A96 M141 I171 W175	L88-H92 PolarHBondContact O-CD2 2.9Å; L88-H92 PolarHBondContact O-N 3.46Å; L88-H92 VanDerWaalsContact O-N 3.12Å; F89-H92 PolarHBondContact O-N 2.95Å; I90-H92 PolarHBondContact O-N 3.36Å; H92-L95 PolarHBondContact O-N 3.39Å; H92-A96 WeakPolarHBondContact O-CB 3.21Å; H92-A96 PolarHBondContact O-N 3.49Å; H92-M141 HydrophobicContact CB-SD 3.89Å; H92-I171 HydrophobicContact CB-CG2 4.16Å; H92-W175 AromaticContact ND1-NE1 3.34Å; H92-W175 PolarHBondContact ND1-NE1 2.69Å
93	L	94	Very high	90.3	Very high	2 Å²	2	34.6 Å²	34.6	1%	0.01	17%	0.173	C	C	.	.	H	α-helix	trans	-67.1	-45.5	173.1	-176	47.2	0	0	0	111	F89 I90 R91 L95 A96 D97 M141 L142 M145 Y348	F89-L93 WeakPolarHBondContact O-CB 3.22Å; F89-L93 PolarHBondContact O-N 3.49Å; I90-L93 PolarHBondContact O-N 2.95Å; R91-L93 VanDerWaalsContact C-N 3.35Å; L93-L95 VanDerWaalsContact C-N 3.3Å; L93-L95 PolarHBondContact O-N 2.85Å; L93-A96 WeakPolarHBondContact O-CB 3.35Å; L93-A96 PolarHBondContact O-N 3.2Å; L93-A96 VanDerWaalsContact O-N 3.09Å; L93-D97 VanDerWaalsContact O-CG 3.32Å; L93-D97 PolarHBondContact O-N 3.14Å; L93-M141 HydrophobicContact CD1-CB 3.95Å; L93-L142 HydrophobicContact CD1-CD2 4.11Å; L93-L142 HydrophobicContact CD1-CG 4.43Å; L93-L142 HydrophobicContact CD2-CD2 3.67Å; L93-M145 HydrophobicContact CD2-CE 3.62Å; L93-M145 HydrophobicContact CD2-SD 4.02Å; L93-Y348 WeakPolarHBondContact CD2-OH 3.46Å; L93-Y348 WeakPolarHBondContact CG-OH 3.27Å
94	S	95	Very high	91.7	Very high	0 Å²	0	30.8 Å²	30.8	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-61.4	-35.2	172.8	-67	0	0	0	0	113.2	N69 V72 I90 R91 L98	N69-S94 PolarHBondContact OD1-OG 3.16Å; V72-S94 WeakPolarHBondContact CG1-OG 3.32Å; I90-S94 WeakPolarHBondContact O-CB 3.31Å; I90-S94 PolarHBondContact O-N 2.91Å; I90-S94 PolarHBondContact O-OG 2.95Å; R91-S94 PolarHBondContact O-N 3.17Å; S94-L98 WeakPolarHBondContact O-CB 3.3Å; S94-L98 VanDerWaalsContact O-CG 3.31Å; S94-L98 WeakPolarHBondContact O-CG 3.46Å; S94-L98 PolarHBondContact O-N 3.45Å
95	L	96.1	Very high	92.5	Very high	72 Å²	72	28.1 Å²	28.1	38%	0.377	13%	0.129	S	C	.	.	H	α-helix	trans	-66.5	-39.5	172.5	-72.3	170.8	0	0	0	112.2	L73 R91 H92 L93 L98 A99 W175	L73-L95 HydrophobicContact CD1-CD2 3.95Å; L73-L95 HydrophobicContact CD1-CG 4.43Å; L73-L95 HydrophobicContact CD2-CG 4.35Å; R91-L95 HydrophobicContact CG-CD1 4.38Å; R91-L95 WeakPolarHBondContact O-CG 3.45Å; R91-L95 PolarHBondContact O-N 3.31Å; H92-L95 PolarHBondContact O-N 3.39Å; L93-L95 VanDerWaalsContact C-N 3.3Å; L93-L95 PolarHBondContact O-N 2.85Å; L95-L98 PolarHBondContact O-N 2.81Å; L95-A99 PolarHBondContact O-N 3.36Å; L95-W175 HydrophobicContact CB-CZ2 4.38Å
96	A	96.2	Very high	93.1	Very high	0 Å²	0	27.5 Å²	27.5	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-66.7	-39.8	175.6	0	0	0	0	0	111.8	H92 L93 A99 V100 A137 M141 W175	H92-A96 WeakPolarHBondContact O-CB 3.21Å; H92-A96 PolarHBondContact O-N 3.49Å; L93-A96 WeakPolarHBondContact O-CB 3.35Å; L93-A96 PolarHBondContact O-N 3.2Å; L93-A96 VanDerWaalsContact O-N 3.09Å; A96-A99 WeakPolarHBondContact O-CB 3.31Å; A96-A99 PolarHBondContact O-N 3.35Å; A96-V100 WeakPolarHBondContact O-CG2 3.34Å; A96-V100 PolarHBondContact O-N 3Å; A96-A137 HydrophobicContact CB-CB 4.11Å; A96-M141 HydrophobicContact CB-CG 4.06Å; A96-W175 HydrophobicContact CB-CH2 4.2Å; A96-W175 HydrophobicContact CB-CZ2 4.34Å
97	D	95.3	Very high	93.5	Very high	0 Å²	0	28.4 Å²	28.4	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-69.8	-33.5	176.7	-63.4	-29.9	0	0	0	112.3	L93 V100 A101 S138 N344	L93-D97 VanDerWaalsContact O-CG 3.32Å; L93-D97 PolarHBondContact O-N 3.14Å; D97-V100 WeakPolarHBondContact O-CB 3.38Å; D97-V100 PolarHBondContact O-N 2.89Å; D97-A101 PolarHBondContact O-N 3.47Å; D97-S138 PolarHBondContact OD1-OG 3.12Å; D97-N344 PolarHBondContact OD2-ND2 3.39Å
98	L	95.7	Very high	93.7	Very high	23 Å²	23	29 Å²	29	12%	0.12	14%	0.139	C	C	.	.	H	α-helix	trans	-65.9	-39.1	168.4	-74.7	175.7	0	0	0	111.6	V66 N69 L73 S94 L95 V100 A101 F102	V66-L98 HydrophobicContact CB-CD2 4.49Å; V66-L98 HydrophobicContact CG2-CD2 4.41Å; N69-L98 HydrophobicContact CB-CD2 3.94Å; N69-L98 HydrophobicContact CB-CG 3.85Å; L73-L98 HydrophobicContact CD1-CD1 3.48Å; L73-L98 VanDerWaalsContact CD1-CD1 3.48Å; S94-L98 WeakPolarHBondContact O-CB 3.3Å; S94-L98 VanDerWaalsContact O-CG 3.31Å; S94-L98 WeakPolarHBondContact O-CG 3.46Å; S94-L98 PolarHBondContact O-N 3.45Å; L95-L98 PolarHBondContact O-N 2.81Å; L98-V100 VanDerWaalsContact C-N 3.3Å; L98-V100 PolarHBondContact O-N 2.97Å; L98-A101 PolarHBondContact O-N 3.17Å; L98-A101 VanDerWaalsContact O-N 3.15Å; L98-F102 HydrophobicContact CD2-CE2 4.32Å; L98-F102 WeakPolarHBondContact O-CD2 3.14Å; L98-F102 PolarHBondContact O-N 2.97Å
99	A	95.2	Very high	93.7	Very high	11 Å²	11	28.4 Å²	28.4	9%	0.091	14%	0.136	C	C	.	.	H	α-helix	trans	-60.9	-40.9	173	0	0	0	0	0	111.1	L95 A96 F103	L95-A99 PolarHBondContact O-N 3.36Å; A96-A99 WeakPolarHBondContact O-CB 3.31Å; A96-A99 PolarHBondContact O-N 3.35Å; A99-F103 HydrophobicContact CB-CD2 4Å; A99-F103 HydrophobicContact CB-CE2 4.34Å; A99-F103 WeakPolarHBondContact O-CA 3.35Å; A99-F103 WeakPolarHBondContact O-CB 3.34Å; A99-F103 WeakPolarHBondContact O-CD2 3.19Å; A99-F103 PolarHBondContact O-N 2.9Å
100	V	94.7	Very high	93.7	Very high	4 Å²	4	31 Å²	31	2%	0.024	15%	0.154	C	C	.	.	I	π-helix	trans	-60.1	-47.1	170.4	169.5	0	0	0	0	111	A96 D97 L98 F102 Q104 V105 G134 S341	A96-V100 WeakPolarHBondContact O-CG2 3.34Å; A96-V100 PolarHBondContact O-N 3Å; D97-V100 WeakPolarHBondContact O-CB 3.38Å; D97-V100 PolarHBondContact O-N 2.89Å; L98-V100 VanDerWaalsContact C-N 3.3Å; L98-V100 PolarHBondContact O-N 2.97Å; V100-F102 PolarHBondContact O-N 3.37Å; V100-Q104 HydrophobicContact CG1-CB 4.26Å; V100-Q104 CarbonylContact O-C 3.58Å; V100-Q104 VanDerWaalsContact O-CA 3.26Å; V100-Q104 WeakPolarHBondContact O-CA 3.36Å; V100-Q104 WeakPolarHBondContact O-CB 3.39Å; V100-Q104 PolarHBondContact O-N 3.27Å; V100-V105 HydrophobicContact CG1-CG2 4.34Å; V100-V105 PolarHBondContact O-N 2.98Å; V100-G134 VanDerWaalsContact CG2-C 3.48Å; V100-G134 VanDerWaalsContact CG2-O 3.3Å; V100-G134 WeakPolarHBondContact CG2-O 3.41Å; V100-S341 WeakPolarHBondContact CG1-OG 3.41Å
101	A	94.7	Very high	93.7	Very high	0 Å²	0	32 Å²	32	0%	0	16%	0.158	C	C	.	.	I	π-helix	trans	-60.7	-50.1	179.6	0	0	0	0	0	112.5	F62 A65 V66 D97 L98 V105 L106	F62-A101 HydrophobicContact CD2-CB 4.14Å; F62-A101 WeakPolarHBondContact CD2-O 3.21Å; F62-A101 HydrophobicContact CE2-CB 4.33Å; F62-A101 WeakPolarHBondContact CE2-O 3.48Å; A65-A101 HydrophobicContact CB-CB 4.05Å; V66-A101 HydrophobicContact CG2-CB 3.93Å; D97-A101 PolarHBondContact O-N 3.47Å; L98-A101 PolarHBondContact O-N 3.17Å; L98-A101 VanDerWaalsContact O-N 3.15Å; A101-V105 WeakPolarHBondContact O-CB 3.5Å; A101-V105 PolarHBondContact O-N 2.87Å; A101-L106 WeakPolarHBondContact O-CB 3.44Å; A101-L106 PolarHBondContact O-N 2.92Å
102	F	95.5	Very high	93.4	Very high	92 Å²	92	28.3 Å²	28.3	40%	0.404	14%	0.144	S	C	.	.	I	π-helix	trans	-79.8	-32.4	-174.9	-81.2	-75.7	0	0	0	114.6	F62 V66 L98 V100 L106 P107	F62-F102 HydrophobicContact CE2-CD1 4.18Å; F62-F102 HydrophobicContact CE2-CE1 4.31Å; F62-F102 HydrophobicContact CE2-CG 4.49Å; F62-F102 HydrophobicContact CZ-CD1 4.21Å; F62-F102 AromaticContact CZ-CE1 3.93Å; F62-F102 HydrophobicContact CZ-CE1 3.93Å; F62-F102 HydrophobicContact CZ-CZ 4.39Å; V66-F102 HydrophobicContact CG1-CE2 4.47Å; V66-F102 HydrophobicContact CG1-CZ 4.4Å; V66-F102 HydrophobicContact CG2-CE2 3.98Å; V66-F102 HydrophobicContact CG2-CZ 4.16Å; L98-F102 HydrophobicContact CD2-CE2 4.32Å; L98-F102 WeakPolarHBondContact O-CD2 3.14Å; L98-F102 PolarHBondContact O-N 2.97Å; V100-F102 PolarHBondContact O-N 3.37Å; F102-L106 HydrophobicContact CD1-CD2 4.11Å; F102-P107 VanDerWaalsContact O-CD 3.28Å; F102-P107 WeakPolarHBondContact O-CD 3.46Å
103	F	93.5	Very high	93.2	Very high	82 Å²	82	30.5 Å²	30.5	36%	0.36	16%	0.157	S	C	.	.	I	π-helix	trans	-105.2	-21.8	-175.7	-58.3	-49.4	0	0	0	113.7	A99 P107 L130 Q131	A99-F103 HydrophobicContact CB-CD2 4Å; A99-F103 HydrophobicContact CB-CE2 4.34Å; A99-F103 WeakPolarHBondContact O-CA 3.35Å; A99-F103 WeakPolarHBondContact O-CB 3.34Å; A99-F103 WeakPolarHBondContact O-CD2 3.19Å; A99-F103 PolarHBondContact O-N 2.9Å; F103-P107 VanDerWaalsContact C-CD 3.5Å; F103-P107 WeakPolarHBondContact O-CD 3.44Å; F103-P107 VanDerWaalsContact O-CG 3.27Å; F103-P107 WeakPolarHBondContact O-CG 3.06Å; F103-L130 HydrophobicContact CB-CB 3.73Å; F103-L130 HydrophobicContact CD1-CB 4.16Å; F103-L130 HydrophobicContact CD1-CD1 3.82Å; F103-L130 HydrophobicContact CD2-CB 4.35Å; F103-L130 HydrophobicContact CE1-CD1 3.95Å; F103-L130 HydrophobicContact CG-CB 3.84Å; F103-L130 HydrophobicContact CG-CD1 4.28Å; F103-L130 HydrophobicContact CG-CG 4.5Å; F103-L130 HydrophobicContact CZ-CD1 4.49Å; F103-Q131 WeakPolarHBondContact O-CG 3.19Å
104	Q	92.1	Very high	93	Very high	30 Å²	30	32.1 Å²	32.1	14%	0.14	17%	0.167	C	C	.	.	I	π-helix	trans	-102.7	-60.9	176.6	-170	-170	-23.9	0	0	112.5	V100 Q108	V100-Q104 HydrophobicContact CG1-CB 4.26Å; V100-Q104 CarbonylContact O-C 3.58Å; V100-Q104 VanDerWaalsContact O-CA 3.26Å; V100-Q104 WeakPolarHBondContact O-CA 3.36Å; V100-Q104 WeakPolarHBondContact O-CB 3.39Å; V100-Q104 PolarHBondContact O-N 3.27Å; Q104-Q108 VanDerWaalsContact O-CB 3.22Å; Q104-Q108 WeakPolarHBondContact O-CB 3.11Å; Q104-Q108 PolarHBondContact O-N 3.05Å
105	V	92.5	Very high	92.4	Very high	4 Å²	4	34.9 Å²	34.9	2%	0.024	18%	0.177	C	C	.	.	I	π-helix	trans	-69.8	-48	-172.6	-177.1	0	0	0	0	111	L58 F62 V100 A101 Q108 M109	L58-V105 HydrophobicContact CB-CG1 4.36Å; L58-V105 HydrophobicContact CD2-CG1 3.99Å; F62-V105 HydrophobicContact CB-CG1 3.92Å; V100-V105 HydrophobicContact CG1-CG2 4.34Å; V100-V105 PolarHBondContact O-N 2.98Å; A101-V105 WeakPolarHBondContact O-CB 3.5Å; A101-V105 PolarHBondContact O-N 2.87Å; V105-Q108 PolarHBondContact O-N 3.31Å; V105-M109 WeakPolarHBondContact O-CB 3.24Å; V105-M109 PolarHBondContact O-N 3.49Å
106	L	93.6	Very high	91.9	Very high	49 Å²	49	33.4 Å²	33.4	26%	0.257	17%	0.167	S	C	.	.	H	α-helix	trans	-62.9	-49.7	-178.5	172.6	65.9	0	0	0	112.8	F62 A101 F102 Q108 M109 C110	F62-L106 HydrophobicContact CD2-CB 4.01Å; F62-L106 HydrophobicContact CE2-CB 3.74Å; F62-L106 HydrophobicContact CE2-CD2 4.29Å; F62-L106 HydrophobicContact CE2-CG 4.43Å; F62-L106 HydrophobicContact CZ-CB 4.39Å; F62-L106 HydrophobicContact CZ-CD1 4.49Å; F62-L106 HydrophobicContact CZ-CD2 4.26Å; A101-L106 WeakPolarHBondContact O-CB 3.44Å; A101-L106 PolarHBondContact O-N 2.92Å; F102-L106 HydrophobicContact CD1-CD2 4.11Å; L106-Q108 VanDerWaalsContact C-N 3.3Å; L106-Q108 PolarHBondContact O-N 2.82Å; L106-M109 HydrophobicContact CD1-CE 3.72Å; L106-M109 PolarHBondContact O-N 2.95Å; L106-C110 PolarHBondContact O-N 3.27Å; L106-C110 PolarHBondContact O-SG 3.41Å; L106-C110 VanDerWaalsContact O-SG 3.34Å
107	P	91.9	Very high	91.6	Very high	30 Å²	30	34.6 Å²	34.6	20%	0.195	17%	0.172	C	C	.	.	H	α-helix	trans	-66.6	-31.3	178.1	-26.1	39.7	0	0	0	113	F102 F103 W111 V127	F102-P107 VanDerWaalsContact O-CD 3.28Å; F102-P107 WeakPolarHBondContact O-CD 3.46Å; F103-P107 VanDerWaalsContact C-CD 3.5Å; F103-P107 WeakPolarHBondContact O-CD 3.44Å; F103-P107 VanDerWaalsContact O-CG 3.27Å; F103-P107 WeakPolarHBondContact O-CG 3.06Å; P107-W111 WeakPolarHBondContact O-CB 3.27Å; P107-W111 PolarHBondContact O-N 2.82Å; P107-V127 HydrophobicContact CB-CG1 3.72Å; P107-V127 HydrophobicContact CG-CG1 4.33Å
108	Q	90.2	Very high	91.3	Very high	35 Å²	35	43.9 Å²	43.9	16%	0.164	21%	0.207	C	C	.	.	H	α-helix	trans	-64.3	-48.8	171.8	-177.7	61.9	38.2	0	0	110.7	L58 Q104 V105 L106 C110 W111 D112	L58-Q108 HydrophobicContact CD1-CG 3.91Å; Q104-Q108 VanDerWaalsContact O-CB 3.22Å; Q104-Q108 WeakPolarHBondContact O-CB 3.11Å; Q104-Q108 PolarHBondContact O-N 3.05Å; V105-Q108 PolarHBondContact O-N 3.31Å; L106-Q108 VanDerWaalsContact C-N 3.3Å; L106-Q108 PolarHBondContact O-N 2.82Å; Q108-C110 VanDerWaalsContact C-N 3.34Å; Q108-C110 PolarHBondContact O-N 3.41Å; Q108-W111 WeakPolarHBondContact O-CA 3.5Å; Q108-W111 VanDerWaalsContact O-CB 3.25Å; Q108-W111 WeakPolarHBondContact O-CB 3.23Å; Q108-W111 PolarHBondContact O-N 3.46Å; Q108-D112 PolarHBondContact NE2-OD1 2.82Å; Q108-D112 PolarHBondContact NE2-OD2 2.85Å; Q108-D112 VanDerWaalsContact NE2-OD2 3.11Å; Q108-D112 PolarHBondContact O-N 3.04Å; Q108-D112 VanDerWaalsContact O-OD2 3.11Å
109	M	90.9	Very high	90.9	Very high	29 Å²	29	44 Å²	44	14%	0.143	21%	0.214	C	C	.	.	H	α-helix	trans	-59	-44.3	176.1	-174.4	-177	72.1	0	0	112	L58 A59 V105 L106 W111 D112 I113	L58-M109 HydrophobicContact CB-CB 4.05Å; L58-M109 HydrophobicContact CB-CG 4.18Å; L58-M109 HydrophobicContact CD1-CB 4.24Å; A59-M109 VanDerWaalsContact CA-SD 3.59Å; A59-M109 HydrophobicContact CB-SD 3.76Å; V105-M109 WeakPolarHBondContact O-CB 3.24Å; V105-M109 PolarHBondContact O-N 3.49Å; L106-M109 HydrophobicContact CD1-CE 3.72Å; L106-M109 PolarHBondContact O-N 2.95Å; M109-W111 VanDerWaalsContact C-N 3.29Å; M109-W111 PolarHBondContact O-N 3.1Å; M109-D112 PolarHBondContact O-N 3.28Å; M109-I113 HydrophobicContact CG-CD1 4.09Å; M109-I113 VanDerWaalsContact O-CG1 3.28Å; M109-I113 WeakPolarHBondContact O-CG1 3.28Å; M109-I113 PolarHBondContact O-N 3.03Å
110	C	92.6	Very high	90.8	Very high	58 Å²	58	46.6 Å²	46.6	39%	0.392	23%	0.23	S	C	.	.	H	α-helix	trans	-59.4	-42	174.7	-70.5	0	0	0	0	111.5	L106 Q108 I113 T114	L106-C110 PolarHBondContact O-N 3.27Å; L106-C110 PolarHBondContact O-SG 3.41Å; L106-C110 VanDerWaalsContact O-SG 3.34Å; Q108-C110 VanDerWaalsContact C-N 3.34Å; Q108-C110 PolarHBondContact O-N 3.41Å; C110-I113 PolarHBondContact O-N 3.17Å; C110-T114 WeakPolarHBondContact O-CG2 3.46Å; C110-T114 PolarHBondContact O-N 3.02Å; C110-T114 PolarHBondContact O-OG1 2.95Å
111	W	89.2	Confident	90.8	Very high	21 Å²	21	49.1 Å²	49.1	8%	0.08	24%	0.243	C	C	.	.	H	α-helix	trans	-61.1	-46	176.3	-167.6	-62.4	0	0	0	112.1	P107 Q108 M109 I113 T114 Y115 F117 D202 C203	P107-W111 WeakPolarHBondContact O-CB 3.27Å; P107-W111 PolarHBondContact O-N 2.82Å; Q108-W111 WeakPolarHBondContact O-CA 3.5Å; Q108-W111 VanDerWaalsContact O-CB 3.25Å; Q108-W111 WeakPolarHBondContact O-CB 3.23Å; Q108-W111 PolarHBondContact O-N 3.46Å; M109-W111 VanDerWaalsContact C-N 3.29Å; M109-W111 PolarHBondContact O-N 3.1Å; W111-I113 VanDerWaalsContact C-N 3.29Å; W111-I113 PolarHBondContact O-N 2.91Å; W111-T114 PolarHBondContact O-N 3.49Å; W111-Y115 WeakPolarHBondContact O-CA 3.3Å; W111-Y115 PolarHBondContact O-N 3.38Å; W111-F117 HydrophobicContact CE3-CB 3.96Å; W111-F117 AromaticContact CE3-CD2 3.6Å; W111-F117 HydrophobicContact CE3-CD2 3.6Å; W111-F117 HydrophobicContact CE3-CG 4.23Å; W111-F117 HydrophobicContact CH2-CB 3.66Å; W111-F117 HydrophobicContact CH2-CD2 4.41Å; W111-F117 HydrophobicContact CH2-CG 4.34Å; W111-F117 HydrophobicContact CZ2-CB 4.26Å; W111-F117 HydrophobicContact CZ3-CB 3.5Å; W111-F117 AromaticContact CZ3-CD2 3.42Å; W111-F117 HydrophobicContact CZ3-CD2 3.42Å; W111-F117 VanDerWaalsContact CZ3-CD2 3.42Å; W111-F117 HydrophobicContact CZ3-CE2 4.4Å; W111-F117 AromaticContact CZ3-CG 3.76Å; W111-F117 HydrophobicContact CZ3-CG 3.76Å; W111-D202 VanDerWaalsContact CH2-OD1 3.24Å; W111-D202 WeakPolarHBondContact CH2-OD1 3.3Å; W111-D202 VanDerWaalsContact CZ2-CG 3.44Å; W111-D202 WeakPolarHBondContact CZ2-OD1 3.49Å; W111-D202 WeakPolarHBondContact CZ2-OD2 2.95Å; W111-C203 HydrophobicContact CH2-CB 3.48Å; W111-C203 VanDerWaalsContact CH2-CB 3.48Å; W111-C203 WeakPolarHBondContact CH2-O 3.37Å; W111-C203 HydrophobicContact CZ3-CB 3.69Å
112	D	86.6	Confident	90.8	Very high	5 Å²	5	57.1 Å²	57.1	3%	0.027	27%	0.273	C	S	.	.	H	α-helix	trans	-66.6	-33.8	-178.7	-62.6	-35.3	0	0	0	111.4	R2 R46 I55 L58 Q108 M109	R2-D112 IonicContact NH2-OD1 2.76Å; R2-D112 PolarHBondContact NH2-OD1 3.39Å; R46-D112 PolarHBondContact NH1-O 3.26Å; I55-D112 HydrophobicContact CD1-CB 4.41Å; I55-D112 HydrophobicContact CG1-CB 3.8Å; L58-D112 WeakPolarHBondContact CD1-OD2 3.22Å; Q108-D112 PolarHBondContact NE2-OD1 2.82Å; Q108-D112 PolarHBondContact NE2-OD2 2.85Å; Q108-D112 VanDerWaalsContact NE2-OD2 3.11Å; Q108-D112 PolarHBondContact O-N 3.04Å; Q108-D112 VanDerWaalsContact O-OD2 3.11Å; M109-D112 PolarHBondContact O-N 3.28Å
113	I	91	Very high	90.7	Very high	94 Å²	94	55.3 Å²	55.3	48%	0.482	27%	0.268	S	S	.	.	H	α-helix	trans	-68.5	-50.3	172.4	-67.3	165.6	0	0	0	111.5	I55 M109 C110 W111 Y115	I55-I113 HydrophobicContact CD1-CG1 3.89Å; I55-I113 HydrophobicContact CG1-CG1 4.04Å; I55-I113 HydrophobicContact CG2-CD1 4.21Å; I55-I113 HydrophobicContact CG2-CG1 3.9Å; M109-I113 HydrophobicContact CG-CD1 4.09Å; M109-I113 VanDerWaalsContact O-CG1 3.28Å; M109-I113 WeakPolarHBondContact O-CG1 3.28Å; M109-I113 PolarHBondContact O-N 3.03Å; C110-I113 PolarHBondContact O-N 3.17Å; W111-I113 VanDerWaalsContact C-N 3.29Å; W111-I113 PolarHBondContact O-N 2.91Å; I113-Y115 VanDerWaalsContact C-N 3.28Å; I113-Y115 PolarHBondContact O-N 3.35Å
114	T	89.8	Confident	90.8	Very high	36 Å²	36	51.4 Å²	51.4	22%	0.221	25%	0.251	C	S	.	.	H	α-helix	trans	-81.8	-7.7	-173.4	58.6	0	0	0	0	113.6	C110 W111 R116	C110-T114 WeakPolarHBondContact O-CG2 3.46Å; C110-T114 PolarHBondContact O-N 3.02Å; C110-T114 PolarHBondContact O-OG1 2.95Å; W111-T114 PolarHBondContact O-N 3.49Å; T114-R116 WeakPolarHBondContact CB-O 3.37Å; T114-R116 PolarHBondContact O-N 2.96Å; T114-R116 PolarHBondContact OG1-O 3.46Å
115	Y	84.2	Confident	91	Very high	58 Å²	58	53.1 Å²	53.1	23%	0.227	26%	0.256	C	S	.	.	S	Bend	trans	63.5	-34.1	-174.2	-178.3	-118.6	0	0	0	114.9	D44 R46 W111 I113	D44-Y115 WeakPolarHBondContact CB-OH 3.41Å; D44-Y115 PolarHBondContact O-OH 3.28Å; D44-Y115 VanDerWaalsContact O-OH 3.05Å; D44-Y115 PolarHBondContact OD1-OH 3.14Å; D44-Y115 PolarHBondContact OD2-OH 3.46Å; D44-Y115 VanDerWaalsContact OD2-OH 3.04Å; R46-Y115 HydrophobicContact CB-CD2 4.39Å; R46-Y115 HydrophobicContact CB-CE2 3.83Å; R46-Y115 HydrophobicContact CG-CE2 4.35Å; W111-Y115 WeakPolarHBondContact O-CA 3.3Å; W111-Y115 PolarHBondContact O-N 3.38Å; I113-Y115 VanDerWaalsContact C-N 3.28Å; I113-Y115 PolarHBondContact O-N 3.35Å
116	R	85.5	Confident	91.1	Very high	40 Å²	40	55.1 Å²	55.1	15%	0.151	27%	0.268	C	S	.	.	S	Bend	trans	-125.5	152.3	176.6	-59.1	-60.9	-177.9	97.8	-12.8	110.7	D44 T114 R118 D202	D44-R116 IonicContact OD2-CZ 3.36Å; D44-R116 IonicContact OD2-NH2 3.56Å; D44-R116 PolarHBondContact OD2-NH2 3.11Å; T114-R116 WeakPolarHBondContact CB-O 3.37Å; T114-R116 PolarHBondContact O-N 2.96Å; T114-R116 PolarHBondContact OG1-O 3.46Å; R116-R118 PolarHBondContact O-N 3.12Å; R116-D202 WeakPolarHBondContact CD-OD2 3.39Å
117	F	89.5	Confident	91.2	Very high	26 Å²	26	54 Å²	54	11%	0.114	26%	0.263	C	S	.	.			trans	-65.5	123.5	172.7	-170.3	-104.1	0	0	0	111.8	W111 L123 C124 V127 M191 D202 C203	W111-F117 HydrophobicContact CE3-CB 3.96Å; W111-F117 AromaticContact CE3-CD2 3.6Å; W111-F117 HydrophobicContact CE3-CD2 3.6Å; W111-F117 HydrophobicContact CE3-CG 4.23Å; W111-F117 HydrophobicContact CH2-CB 3.66Å; W111-F117 HydrophobicContact CH2-CD2 4.41Å; W111-F117 HydrophobicContact CH2-CG 4.34Å; W111-F117 HydrophobicContact CZ2-CB 4.26Å; W111-F117 HydrophobicContact CZ3-CB 3.5Å; W111-F117 AromaticContact CZ3-CD2 3.42Å; W111-F117 HydrophobicContact CZ3-CD2 3.42Å; W111-F117 VanDerWaalsContact CZ3-CD2 3.42Å; W111-F117 HydrophobicContact CZ3-CE2 4.4Å; W111-F117 AromaticContact CZ3-CG 3.76Å; W111-F117 HydrophobicContact CZ3-CG 3.76Å; F117-L123 HydrophobicContact CE1-CB 4.43Å; F117-L123 HydrophobicContact CZ-CB 4.28Å; F117-L123 HydrophobicContact CZ-CD2 4.24Å; F117-L123 HydrophobicContact CZ-CG 3.96Å; F117-C124 HydrophobicContact CD1-CB 4.16Å; F117-C124 HydrophobicContact CE1-CB 3.7Å; F117-C124 HydrophobicContact CZ-CB 4.12Å; F117-V127 HydrophobicContact CE2-CB 4.39Å; F117-V127 HydrophobicContact CE2-CG1 4.45Å; F117-V127 HydrophobicContact CE2-CG2 4.24Å; F117-V127 HydrophobicContact CZ-CG2 4.28Å; F117-M191 HydrophobicContact CB-SD 4.4Å; F117-M191 HydrophobicContact CD1-CE 4.29Å; F117-M191 HydrophobicContact CD1-SD 3.58Å; F117-M191 VanDerWaalsContact CD1-SD 3.58Å; F117-M191 HydrophobicContact CE1-SD 4.32Å; F117-M191 HydrophobicContact CG-SD 4.38Å; F117-D202 VanDerWaalsContact CB-OD1 3.28Å; F117-D202 WeakPolarHBondContact CB-OD1 3.4Å; F117-D202 PolarHBondContact N-OD1 3.27Å; F117-C203 HydrophobicContact CB-CB 3.86Å; F117-C203 HydrophobicContact CD1-CB 3.96Å; F117-C203 HydrophobicContact CD2-CB 4.37Å; F117-C203 HydrophobicContact CG-CB 3.8Å
118	R	87.5	Confident	91.4	Very high	195 Å²	195	53 Å²	53	74%	0.736	26%	0.255	S	S	*	.			trans	-99.2	94.5	173.9	-66	-174.3	-178.2	158.9	1.6	109.8	R116	R116-R118 PolarHBondContact O-N 3.12Å
119	G	88.9	Confident	91.6	Very high	26 Å²	26	51.4 Å²	51.4	27%	0.268	25%	0.248	S	C	.	.	S	Bend	trans	173.7	168.3	175.4	0	0	0	0	0	114
120	P	93.1	Very high	91.9	Very high	64 Å²	64	52.1 Å²	52.1	42%	0.416	25%	0.252	S	S	.	.			trans	-72.7	167	172.4	31.3	-35.8	0	0	0	112.1	W122 L123 C124	P120-W122 VanDerWaalsContact C-N 3.35Å; P120-W122 HydrophobicContact CG-CD2 4.3Å; P120-W122 HydrophobicContact CG-CG 4.28Å; P120-W122 HydrophobicContact CG-CZ2 4.11Å; P120-W122 PolarHBondContact O-N 3.28Å; P120-L123 HydrophobicContact CG-CB 3.98Å; P120-L123 PolarHBondContact O-N 2.81Å; P120-L123 VanDerWaalsContact O-N 3.08Å; P120-C124 PolarHBondContact O-N 3.41Å
121	D	93.7	Very high	92	Very high	58 Å²	58	49.8 Å²	49.8	31%	0.31	24%	0.235	S	C	.	.	H	α-helix	trans	-54.7	-43.8	-179.2	-176.9	66.6	0	0	0	113.7	L123 C124 R125 S190 M191	D121-L123 VanDerWaalsContact C-N 3.27Å; D121-L123 PolarHBondContact O-N 3.01Å; D121-C124 WeakPolarHBondContact O-CB 3.5Å; D121-C124 PolarHBondContact O-N 2.9Å; D121-R125 WeakPolarHBondContact O-CG 3.35Å; D121-R125 PolarHBondContact O-N 3.42Å; D121-R125 VanDerWaalsContact O-N 3.11Å; D121-R125 IonicContact OD1-CZ 3.61Å; D121-R125 IonicContact OD1-NE 2.76Å; D121-R125 IonicContact OD1-NH2 3.29Å; D121-R125 PolarHBondContact OD1-NH2 3.26Å; D121-R125 IonicContact OD2-CZ 2.7Å; D121-R125 VanDerWaalsContact OD2-CZ 3.29Å; D121-R125 IonicContact OD2-NE 3.85Å; D121-R125 PolarHBondContact OD2-NE 3.19Å; D121-R125 IonicContact OD2-NH2 3.05Å; D121-R125 PolarHBondContact OD2-NH2 2.96Å; D121-S190 WeakPolarHBondContact OD1-CA 3.45Å; D121-M191 HydrophobicContact CB-CB 4.1Å; D121-M191 HydrophobicContact CB-CG 4.18Å; D121-M191 PolarHBondContact OD1-N 3.47Å
122	W	95	Very high	92.2	Very high	167 Å²	167	48.8 Å²	48.8	63%	0.633	23%	0.232	S	C	*	.	H	α-helix	trans	-61.4	-36.7	179	70.8	-100	0	0	0	112.2	P120 R125 V126	P120-W122 VanDerWaalsContact C-N 3.35Å; P120-W122 HydrophobicContact CG-CD2 4.3Å; P120-W122 HydrophobicContact CG-CG 4.28Å; P120-W122 HydrophobicContact CG-CZ2 4.11Å; P120-W122 PolarHBondContact O-N 3.28Å; W122-R125 PolarHBondContact O-N 2.99Å; W122-V126 HydrophobicContact CE3-CG2 4.35Å; W122-V126 VanDerWaalsContact O-CG2 3.28Å; W122-V126 WeakPolarHBondContact O-CG2 3.38Å; W122-V126 PolarHBondContact O-N 3.05Å
123	L	94.6	Very high	92.7	Very high	55 Å²	55	50 Å²	50	29%	0.288	24%	0.237	S	C	.	.	H	α-helix	trans	-71	-39.3	180	-173.8	64.1	0	0	0	110.5	F117 P120 D121 R125 V126 V127	F117-L123 HydrophobicContact CE1-CB 4.43Å; F117-L123 HydrophobicContact CZ-CB 4.28Å; F117-L123 HydrophobicContact CZ-CD2 4.24Å; F117-L123 HydrophobicContact CZ-CG 3.96Å; P120-L123 HydrophobicContact CG-CB 3.98Å; P120-L123 PolarHBondContact O-N 2.81Å; P120-L123 VanDerWaalsContact O-N 3.08Å; D121-L123 VanDerWaalsContact C-N 3.27Å; D121-L123 PolarHBondContact O-N 3.01Å; L123-R125 PolarHBondContact O-N 3.49Å; L123-V126 PolarHBondContact O-N 3.46Å; L123-V127 HydrophobicContact CD1-CG2 4.26Å; L123-V127 HydrophobicContact CG-CG2 4.29Å; L123-V127 WeakPolarHBondContact O-CB 3.42Å; L123-V127 VanDerWaalsContact O-CG2 3.23Å; L123-V127 WeakPolarHBondContact O-CG2 3.3Å; L123-V127 PolarHBondContact O-N 2.88Å
124	C	94.6	Very high	92.9	Very high	0 Å²	0	45.5 Å²	45.5	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-53.9	-52.2	172.1	157.3	0	0	0	0	111.1	F117 P120 D121 V126 V127 K128 M191 C203	F117-C124 HydrophobicContact CD1-CB 4.16Å; F117-C124 HydrophobicContact CE1-CB 3.7Å; F117-C124 HydrophobicContact CZ-CB 4.12Å; P120-C124 PolarHBondContact O-N 3.41Å; D121-C124 WeakPolarHBondContact O-CB 3.5Å; D121-C124 PolarHBondContact O-N 2.9Å; C124-V126 PolarHBondContact O-N 2.87Å; C124-V127 PolarHBondContact O-N 2.82Å; C124-K128 VanDerWaalsContact O-CG 3.29Å; C124-K128 WeakPolarHBondContact O-CG 3.39Å; C124-K128 PolarHBondContact O-N 2.81Å; C124-M191 HydrophobicContact CB-CG 3.84Å; C124-M191 HydrophobicContact CB-SD 4.09Å; C124-C203 HydrophobicContact CB-CB 3.52Å; C124-C203 WeakPolarHBondContact CB-SG 3.27Å; C124-C203 WeakPolarHBondContact SG-CB 3.49Å; C124-C203 CovalentContact SG-SG 2.01Å; C124-C203 PolarHBondContact SG-SG 3.39Å
125	R	95.5	Very high	93.1	Very high	66 Å²	66	44.4 Å²	44.4	25%	0.249	21%	0.207	C	C	.	.	H	α-helix	trans	-62	-44.9	-179.5	-64.8	-179.4	-163.5	-99.2	-3.7	112.4	D121 W122 L123 K128 H129 Y186 F189 S190	D121-R125 WeakPolarHBondContact O-CG 3.35Å; D121-R125 PolarHBondContact O-N 3.42Å; D121-R125 VanDerWaalsContact O-N 3.11Å; D121-R125 IonicContact OD1-CZ 3.61Å; D121-R125 IonicContact OD1-NE 2.76Å; D121-R125 IonicContact OD1-NH2 3.29Å; D121-R125 PolarHBondContact OD1-NH2 3.26Å; D121-R125 IonicContact OD2-CZ 2.7Å; D121-R125 VanDerWaalsContact OD2-CZ 3.29Å; D121-R125 IonicContact OD2-NE 3.85Å; D121-R125 PolarHBondContact OD2-NE 3.19Å; D121-R125 IonicContact OD2-NH2 3.05Å; D121-R125 PolarHBondContact OD2-NH2 2.96Å; W122-R125 PolarHBondContact O-N 2.99Å; L123-R125 PolarHBondContact O-N 3.49Å; R125-K128 PolarHBondContact O-N 3.41Å; R125-H129 WeakPolarHBondContact O-CB 3.17Å; R125-H129 PolarHBondContact O-N 2.91Å; R125-Y186 HydrophobicContact CB-CD1 3.85Å; R125-Y186 HydrophobicContact CB-CE1 4.27Å; R125-Y186 PolarHBondContact NH1-O 3.38Å; R125-F189 WeakPolarHBondContact CG-O 3.41Å; R125-F189 PolarHBondContact NH1-O 3.03Å; R125-F189 VanDerWaalsContact NH1-O 3.15Å; R125-S190 VanDerWaalsContact NH2-CB 3.3Å
126	V	95.9	Very high	93.7	Very high	46 Å²	46	41.7 Å²	41.7	28%	0.279	20%	0.196	S	C	.	.	H	α-helix	trans	-64.4	-44.6	178.4	170.7	0	0	0	0	111.2	W122 L123 C124 K128 H129 L130 Y186	W122-V126 HydrophobicContact CE3-CG2 4.35Å; W122-V126 VanDerWaalsContact O-CG2 3.28Å; W122-V126 WeakPolarHBondContact O-CG2 3.38Å; W122-V126 PolarHBondContact O-N 3.05Å; L123-V126 PolarHBondContact O-N 3.46Å; C124-V126 PolarHBondContact O-N 2.87Å; V126-K128 PolarHBondContact O-N 3.29Å; V126-H129 PolarHBondContact O-N 3.43Å; V126-L130 HydrophobicContact CG1-CD1 3.78Å; V126-L130 HydrophobicContact CG1-CG 4.26Å; V126-L130 WeakPolarHBondContact O-CB 3.28Å; V126-L130 VanDerWaalsContact O-CG 3.31Å; V126-L130 WeakPolarHBondContact O-CG 3.21Å; V126-L130 PolarHBondContact O-N 3.46Å; V126-Y186 HydrophobicContact CG2-CE1 4.21Å
127	V	95.4	Very high	94.2	Very high	24 Å²	24	39.8 Å²	39.8	15%	0.145	19%	0.188	C	C	.	.	H	α-helix	trans	-59.5	-49.6	176.6	168.4	0	0	0	0	110	P107 F117 L123 C124 H129 L130 Q131	P107-V127 HydrophobicContact CB-CG1 3.72Å; P107-V127 HydrophobicContact CG-CG1 4.33Å; F117-V127 HydrophobicContact CE2-CB 4.39Å; F117-V127 HydrophobicContact CE2-CG1 4.45Å; F117-V127 HydrophobicContact CE2-CG2 4.24Å; F117-V127 HydrophobicContact CZ-CG2 4.28Å; L123-V127 HydrophobicContact CD1-CG2 4.26Å; L123-V127 HydrophobicContact CG-CG2 4.29Å; L123-V127 WeakPolarHBondContact O-CB 3.42Å; L123-V127 VanDerWaalsContact O-CG2 3.23Å; L123-V127 WeakPolarHBondContact O-CG2 3.3Å; L123-V127 PolarHBondContact O-N 2.88Å; C124-V127 PolarHBondContact O-N 2.82Å; V127-H129 VanDerWaalsContact C-N 3.33Å; V127-H129 PolarHBondContact O-N 3.08Å; V127-L130 PolarHBondContact O-N 3.34Å; V127-Q131 HydrophobicContact CG1-CG 4.32Å; V127-Q131 VanDerWaalsContact O-CG 3.27Å; V127-Q131 WeakPolarHBondContact O-CG 3.31Å; V127-Q131 PolarHBondContact O-N 3.33Å
128	K	94.9	Very high	94.5	Very high	9 Å²	9	38.8 Å²	38.8	4%	0.039	19%	0.185	C	C	.	.	H	α-helix	trans	-61.1	-41.1	178.3	-65.6	-69.7	-179.7	-170.5	0	112.2	C124 R125 V126 Q131 V132 Q185 F189 C203	C124-K128 VanDerWaalsContact O-CG 3.29Å; C124-K128 WeakPolarHBondContact O-CG 3.39Å; C124-K128 PolarHBondContact O-N 2.81Å; R125-K128 PolarHBondContact O-N 3.41Å; V126-K128 PolarHBondContact O-N 3.29Å; K128-Q131 PolarHBondContact O-N 3.45Å; K128-V132 WeakPolarHBondContact O-CG2 3.28Å; K128-V132 PolarHBondContact O-N 3.41Å; K128-Q185 HydrophobicContact CB-CB 4.3Å; K128-F189 HydrophobicContact CB-CB 4.15Å; K128-F189 HydrophobicContact CB-CD1 4.48Å; K128-F189 HydrophobicContact CB-CD2 3.99Å; K128-F189 HydrophobicContact CB-CG 3.94Å; K128-F189 HydrophobicContact CD-CD1 3.65Å; K128-F189 HydrophobicContact CD-CD2 4.38Å; K128-F189 HydrophobicContact CD-CE1 3.73Å; K128-F189 HydrophobicContact CD-CE2 4.47Å; K128-F189 HydrophobicContact CD-CG 3.99Å; K128-F189 HydrophobicContact CD-CZ 4.16Å; K128-F189 HydrophobicContact CG-CB 3.85Å; K128-F189 HydrophobicContact CG-CD1 3.69Å; K128-F189 HydrophobicContact CG-CD2 4.09Å; K128-F189 HydrophobicContact CG-CE1 4.26Å; K128-F189 HydrophobicContact CG-CG 3.58Å; K128-C203 VanDerWaalsContact CE-SG 3.52Å
129	H	96.1	Very high	94.9	Very high	3 Å²	3	29.5 Å²	29.5	1%	0.014	15%	0.15	C	C	.	.	H	α-helix	trans	-59	-49.3	173.5	177.4	77.3	0	0	0	112.3	R125 V126 V127 V132 F133 F179 S182 Q185 Y186	R125-H129 WeakPolarHBondContact O-CB 3.17Å; R125-H129 PolarHBondContact O-N 2.91Å; V126-H129 PolarHBondContact O-N 3.43Å; V127-H129 VanDerWaalsContact C-N 3.33Å; V127-H129 PolarHBondContact O-N 3.08Å; H129-V132 PolarHBondContact O-N 3.47Å; H129-F133 VanDerWaalsContact O-CB 3.26Å; H129-F133 WeakPolarHBondContact O-CB 2.98Å; H129-F133 PolarHBondContact O-N 3.4Å; H129-F179 AromaticContact NE2-CD2 3.57Å; H129-F179 AromaticContact NE2-CE2 3.37Å; H129-F179 WeakPolarHBondContact NE2-CE2 3.38Å; H129-S182 PolarHBondContact CE1-OG 3.1Å; H129-S182 PolarHBondContact ND1-O 3.33Å; H129-S182 PolarHBondContact ND1-OG 2.93Å; H129-Q185 HydrophobicContact CB-CB 4.13Å; H129-Y186 HydrophobicContact CB-CD2 4.49Å; H129-Y186 HydrophobicContact CB-CE1 4.41Å; H129-Y186 HydrophobicContact CB-CE2 3.86Å; H129-Y186 AromaticContact CD2-CE2 4Å; H129-Y186 PolarHBondContact CD2-OH 2.91Å; H129-Y186 AromaticContact CE1-CE2 3.8Å; H129-Y186 AromaticContact CG-CE2 3.46Å; H129-Y186 VanDerWaalsContact CG-CE2 3.46Å; H129-Y186 AromaticContact CG-CZ 3.7Å; H129-Y186 AromaticContact ND1-CD2 3.98Å; H129-Y186 AromaticContact ND1-CE2 3.35Å; H129-Y186 WeakPolarHBondContact ND1-CE2 3.48Å
130	L	95.9	Very high	95.3	Very high	43 Å²	43	29.7 Å²	29.7	23%	0.225	14%	0.143	C	C	.	.	H	α-helix	trans	-68.5	-34.9	-178.2	-67.4	173.4	0	0	0	112.7	F103 V126 V127 V132 F133 G134	F103-L130 HydrophobicContact CB-CB 3.73Å; F103-L130 HydrophobicContact CD1-CB 4.16Å; F103-L130 HydrophobicContact CD1-CD1 3.82Å; F103-L130 HydrophobicContact CD2-CB 4.35Å; F103-L130 HydrophobicContact CE1-CD1 3.95Å; F103-L130 HydrophobicContact CG-CB 3.84Å; F103-L130 HydrophobicContact CG-CD1 4.28Å; F103-L130 HydrophobicContact CG-CG 4.5Å; F103-L130 HydrophobicContact CZ-CD1 4.49Å; V126-L130 HydrophobicContact CG1-CD1 3.78Å; V126-L130 HydrophobicContact CG1-CG 4.26Å; V126-L130 WeakPolarHBondContact O-CB 3.28Å; V126-L130 VanDerWaalsContact O-CG 3.31Å; V126-L130 WeakPolarHBondContact O-CG 3.21Å; V126-L130 PolarHBondContact O-N 3.46Å; V127-L130 PolarHBondContact O-N 3.34Å; L130-V132 VanDerWaalsContact C-N 3.33Å; L130-V132 PolarHBondContact O-N 2.91Å; L130-F133 HydrophobicContact CD2-CD1 4.4Å; L130-F133 PolarHBondContact O-N 3.45Å; L130-G134 PolarHBondContact O-N 2.95Å
131	Q	94.6	Very high	95.4	Very high	9 Å²	9	26.8 Å²	26.8	4%	0.042	12%	0.124	C	C	.	.	H	α-helix	trans	-53.9	-52	170.8	-74.8	-166.5	-36.9	0	0	110.5	F103 V127 K128 G134 M135	F103-Q131 WeakPolarHBondContact O-CG 3.19Å; V127-Q131 HydrophobicContact CG1-CG 4.32Å; V127-Q131 VanDerWaalsContact O-CG 3.27Å; V127-Q131 WeakPolarHBondContact O-CG 3.31Å; V127-Q131 PolarHBondContact O-N 3.33Å; K128-Q131 PolarHBondContact O-N 3.45Å; Q131-G134 PolarHBondContact O-N 3.23Å; Q131-M135 PolarHBondContact O-N 2.99Å
132	V	94.6	Very high	95.5	Very high	0 Å²	0	24 Å²	24	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-72.7	-39.4	-177.2	177	0	0	0	0	112.4	M1 K128 H129 L130 G134 M135 F136 Q185 M220	M1-V132 HydrophobicContact CE-CG2 3.12Å; K128-V132 WeakPolarHBondContact O-CG2 3.28Å; K128-V132 PolarHBondContact O-N 3.41Å; H129-V132 PolarHBondContact O-N 3.47Å; L130-V132 VanDerWaalsContact C-N 3.33Å; L130-V132 PolarHBondContact O-N 2.91Å; V132-G134 VanDerWaalsContact C-N 3.3Å; V132-G134 PolarHBondContact O-N 2.67Å; V132-M135 PolarHBondContact O-N 3.32Å; V132-F136 HydrophobicContact CG1-CD2 3.48Å; V132-F136 VanDerWaalsContact CG1-CD2 3.48Å; V132-F136 HydrophobicContact CG1-CE2 3.43Å; V132-F136 VanDerWaalsContact CG1-CE2 3.43Å; V132-F136 WeakPolarHBondContact O-CD2 3.48Å; V132-F136 PolarHBondContact O-N 2.94Å; V132-Q185 HydrophobicContact CB-CG 3.9Å; V132-Q185 HydrophobicContact CG1-CG 4.33Å; V132-Q185 VanDerWaalsContact CG2-CD 3.42Å; V132-Q185 HydrophobicContact CG2-CG 3.77Å; V132-M220 HydrophobicContact CB-CE 4.4Å; V132-M220 HydrophobicContact CG1-CE 3.78Å; V132-M220 HydrophobicContact CG1-SD 3.89Å; V132-M220 HydrophobicContact CG2-CE 3.77Å
133	F	97	Very high	95.6	Very high	30 Å²	30	16.9 Å²	16.9	13%	0.132	8%	0.084	C	C	.	.	H	α-helix	trans	-55.5	-45.2	174.1	169.6	-110.1	0	0	0	111.8	H129 L130 M135 F136 A137 W175 F179	H129-F133 VanDerWaalsContact O-CB 3.26Å; H129-F133 WeakPolarHBondContact O-CB 2.98Å; H129-F133 PolarHBondContact O-N 3.4Å; L130-F133 HydrophobicContact CD2-CD1 4.4Å; L130-F133 PolarHBondContact O-N 3.45Å; F133-M135 PolarHBondContact O-N 3.47Å; F133-F136 PolarHBondContact O-N 3.41Å; F133-A137 VanDerWaalsContact O-CB 3.22Å; F133-A137 WeakPolarHBondContact O-CB 3.32Å; F133-A137 PolarHBondContact O-N 3.37Å; F133-W175 HydrophobicContact CE1-CE3 4.23Å; F133-W175 AromaticContact CE1-CZ3 3.75Å; F133-W175 HydrophobicContact CE1-CZ3 3.75Å; F133-W175 AromaticContact CE2-CE3 3.93Å; F133-W175 HydrophobicContact CE2-CE3 3.93Å; F133-W175 HydrophobicContact CE2-CZ3 4.24Å; F133-W175 AromaticContact CZ-CE3 3.38Å; F133-W175 HydrophobicContact CZ-CE3 3.38Å; F133-W175 AromaticContact CZ-CZ3 3.37Å; F133-W175 HydrophobicContact CZ-CZ3 3.37Å; F133-F179 HydrophobicContact CD2-CB 4.17Å; F133-F179 HydrophobicContact CE2-CB 3.99Å; F133-F179 HydrophobicContact CE2-CD2 4.5Å
134	G	94.6	Very high	95.6	Very high	0 Å²	0	15.2 Å²	15.2	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-58.9	-45.2	176.4	0	0	0	0	0	112.6	V100 L130 Q131 V132 A137 S138	V100-G134 VanDerWaalsContact CG2-C 3.48Å; V100-G134 VanDerWaalsContact CG2-O 3.3Å; V100-G134 WeakPolarHBondContact CG2-O 3.41Å; L130-G134 PolarHBondContact O-N 2.95Å; Q131-G134 PolarHBondContact O-N 3.23Å; V132-G134 VanDerWaalsContact C-N 3.3Å; V132-G134 PolarHBondContact O-N 2.67Å; G134-A137 PolarHBondContact O-N 2.88Å; G134-S138 PolarHBondContact O-N 3.49Å
135	M	93.6	Very high	95.6	Very high	14 Å²	14	15.2 Å²	15.2	7%	0.069	8%	0.076	C	C	.	.	H	α-helix	trans	-61	-48.5	177.6	-65.3	178.2	65.9	0	0	112.2	Q131 V132 F133 A139 I224 W304 F308	Q131-M135 PolarHBondContact O-N 2.99Å; V132-M135 PolarHBondContact O-N 3.32Å; F133-M135 PolarHBondContact O-N 3.47Å; M135-A139 WeakPolarHBondContact O-CB 3.28Å; M135-A139 PolarHBondContact O-N 3.37Å; M135-A139 VanDerWaalsContact O-N 3.15Å; M135-I224 HydrophobicContact CB-CD1 3.86Å; M135-I224 HydrophobicContact CB-CG2 4.21Å; M135-I224 HydrophobicContact CE-CD1 3.78Å; M135-I224 HydrophobicContact CE-CG2 4.01Å; M135-I224 HydrophobicContact SD-CD1 4.25Å; M135-W304 HydrophobicContact CE-CE3 4.32Å; M135-W304 HydrophobicContact CE-CH2 3.32Å; M135-W304 HydrophobicContact CE-CZ2 4.24Å; M135-W304 HydrophobicContact CE-CZ3 3.38Å; M135-W304 HydrophobicContact CG-CH2 4.29Å; M135-W304 HydrophobicContact SD-CH2 4.22Å; M135-F308 HydrophobicContact CE-CZ 4.03Å
136	F	96.6	Very high	95.5	Very high	0 Å²	0	12.1 Å²	12.1	0%	0	6%	0.064	C	C	.	.	H	α-helix	trans	-62.6	-45.8	175.6	-83.4	-74.3	0	0	0	111.4	V132 F133 S138 A139 Y140 S178 L181 M220 G223 I224	V132-F136 HydrophobicContact CG1-CD2 3.48Å; V132-F136 VanDerWaalsContact CG1-CD2 3.48Å; V132-F136 HydrophobicContact CG1-CE2 3.43Å; V132-F136 VanDerWaalsContact CG1-CE2 3.43Å; V132-F136 WeakPolarHBondContact O-CD2 3.48Å; V132-F136 PolarHBondContact O-N 2.94Å; F133-F136 PolarHBondContact O-N 3.41Å; F136-S138 PolarHBondContact O-N 3.31Å; F136-A139 PolarHBondContact O-N 2.95Å; F136-Y140 HydrophobicContact CD1-CD2 4.05Å; F136-Y140 AromaticContact CD1-CE2 3.49Å; F136-Y140 HydrophobicContact CD1-CE2 3.49Å; F136-Y140 VanDerWaalsContact CD1-CE2 3.49Å; F136-Y140 HydrophobicContact CE1-CE2 4.07Å; F136-Y140 WeakPolarHBondContact O-CB 3.45Å; F136-Y140 WeakPolarHBondContact O-CD2 3.15Å; F136-Y140 PolarHBondContact O-N 3.41Å; F136-S178 VanDerWaalsContact C-OG 3.26Å; F136-S178 PolarHBondContact O-OG 3.34Å; F136-L181 HydrophobicContact CD1-CB 3.97Å; F136-L181 HydrophobicContact CD1-CD1 3.79Å; F136-L181 HydrophobicContact CD2-CB 4.21Å; F136-L181 HydrophobicContact CE1-CB 3.74Å; F136-L181 HydrophobicContact CE1-CD1 3.64Å; F136-L181 HydrophobicContact CE1-CG 4.29Å; F136-L181 HydrophobicContact CE2-CB 3.98Å; F136-L181 HydrophobicContact CG-CB 4.23Å; F136-L181 HydrophobicContact CZ-CB 3.75Å; F136-L181 HydrophobicContact CZ-CD1 4.43Å; F136-M220 HydrophobicContact CE2-SD 4.26Å; F136-G223 VanDerWaalsContact CE1-C 3.48Å; F136-I224 HydrophobicContact CD1-CG1 3.86Å; F136-I224 HydrophobicContact CD2-CD1 4.08Å; F136-I224 HydrophobicContact CD2-CG1 3.94Å; F136-I224 HydrophobicContact CE1-CG1 3.59Å; F136-I224 HydrophobicContact CE2-CD1 3.83Å; F136-I224 HydrophobicContact CE2-CG1 3.68Å; F136-I224 HydrophobicContact CG-CG1 4.02Å; F136-I224 HydrophobicContact CZ-CD1 4.1Å; F136-I224 HydrophobicContact CZ-CG1 3.49Å; F136-I224 VanDerWaalsContact CZ-CG1 3.49Å
137	A	97.1	Very high	95.4	Very high	0 Å²	0	10.9 Å²	10.9	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-58.4	-48.6	-178.7	0	0	0	0	0	111.4	A96 F133 G134 M141 W175 S178	A96-A137 HydrophobicContact CB-CB 4.11Å; F133-A137 VanDerWaalsContact O-CB 3.22Å; F133-A137 WeakPolarHBondContact O-CB 3.32Å; F133-A137 PolarHBondContact O-N 3.37Å; G134-A137 PolarHBondContact O-N 2.88Å; A137-M141 VanDerWaalsContact O-CB 3.31Å; A137-M141 WeakPolarHBondContact O-CB 3.41Å; A137-M141 WeakPolarHBondContact O-CG 3.48Å; A137-M141 PolarHBondContact O-N 3.25Å; A137-W175 HydrophobicContact CB-CE3 4.09Å; A137-W175 HydrophobicContact CB-CH2 4.24Å; A137-W175 HydrophobicContact CB-CZ3 3.77Å; A137-S178 VanDerWaalsContact CA-OG 3.28Å; A137-S178 WeakPolarHBondContact CA-OG 3.47Å; A137-S178 PolarHBondContact N-OG 3.45Å
138	S	95	Very high	95.2	Very high	5 Å²	5	9.8 Å²	9.8	4%	0.035	5%	0.052	C	C	.	.	H	α-helix	trans	-62.6	-47.9	178.9	-175.3	0	0	0	0	111.3	D97 G134 F136 Y140 M141 L142	D97-S138 PolarHBondContact OD1-OG 3.12Å; G134-S138 PolarHBondContact O-N 3.49Å; F136-S138 PolarHBondContact O-N 3.31Å; S138-Y140 PolarHBondContact O-N 3.24Å; S138-M141 PolarHBondContact O-N 2.9Å; S138-L142 WeakPolarHBondContact O-CG 3.32Å; S138-L142 PolarHBondContact O-N 3.49Å; S138-L142 VanDerWaalsContact O-N 3.17Å
139	A	95.8	Very high	95	Very high	1 Å²	1	10.3 Å²	10.3	1%	0.008	5%	0.054	C	C	.	.	H	α-helix	trans	-62	-44.3	179.1	0	0	0	0	0	113	M135 F136 L142 V143 P228 Y300	M135-A139 WeakPolarHBondContact O-CB 3.28Å; M135-A139 PolarHBondContact O-N 3.37Å; M135-A139 VanDerWaalsContact O-N 3.15Å; F136-A139 PolarHBondContact O-N 2.95Å; A139-L142 WeakPolarHBondContact O-CB 3.39Å; A139-L142 PolarHBondContact O-N 2.97Å; A139-V143 PolarHBondContact O-N 2.69Å; A139-V143 VanDerWaalsContact O-N 3.12Å; A139-P228 HydrophobicContact CB-CG 4.13Å; A139-Y300 HydrophobicContact CB-CE2 4.17Å
140	Y	97.3	Very high	94.8	Very high	30 Å²	30	13 Å²	13	12%	0.118	6%	0.064	C	C	.	.	H	α-helix	trans	-76.1	-27.9	-177.8	-77.2	-114	0	0	0	111.7	F136 S138 L142 V143 V144 L177 L181 G223 P228	F136-Y140 HydrophobicContact CD1-CD2 4.05Å; F136-Y140 AromaticContact CD1-CE2 3.49Å; F136-Y140 HydrophobicContact CD1-CE2 3.49Å; F136-Y140 VanDerWaalsContact CD1-CE2 3.49Å; F136-Y140 HydrophobicContact CE1-CE2 4.07Å; F136-Y140 WeakPolarHBondContact O-CB 3.45Å; F136-Y140 WeakPolarHBondContact O-CD2 3.15Å; F136-Y140 PolarHBondContact O-N 3.41Å; S138-Y140 PolarHBondContact O-N 3.24Å; Y140-L142 VanDerWaalsContact C-N 3.32Å; Y140-V143 PolarHBondContact O-N 3.38Å; Y140-V144 WeakPolarHBondContact O-CG2 3.43Å; Y140-V144 PolarHBondContact O-N 3.17Å; Y140-L177 HydrophobicContact CD1-CD2 3.69Å; Y140-L177 HydrophobicContact CD1-CG 4.2Å; Y140-L177 HydrophobicContact CE1-CD2 3.37Å; Y140-L177 HydrophobicContact CE1-CG 3.91Å; Y140-L181 HydrophobicContact CE1-CD1 4.12Å; Y140-L181 HydrophobicContact CE2-CD1 4.31Å; Y140-L181 WeakPolarHBondContact OH-CD1 3.37Å; Y140-G223 VanDerWaalsContact CE2-O 3.28Å; Y140-G223 WeakPolarHBondContact CE2-O 3.33Å; Y140-G223 PolarHBondContact OH-O 2.95Å; Y140-G223 VanDerWaalsContact OH-O 3.11Å; Y140-P228 HydrophobicContact CE2-CG 4.2Å
141	M	96.1	Very high	94.5	Very high	3 Å²	3	12.5 Å²	12.5	2%	0.015	6%	0.062	C	C	.	.	H	α-helix	trans	-60	-41.1	167.1	-77.5	-50.9	112.3	0	0	111.5	H92 L93 A96 A137 S138 V144 M145 I171 A174 W175	H92-M141 HydrophobicContact CB-SD 3.89Å; L93-M141 HydrophobicContact CD1-CB 3.95Å; A96-M141 HydrophobicContact CB-CG 4.06Å; A137-M141 VanDerWaalsContact O-CB 3.31Å; A137-M141 WeakPolarHBondContact O-CB 3.41Å; A137-M141 WeakPolarHBondContact O-CG 3.48Å; A137-M141 PolarHBondContact O-N 3.25Å; S138-M141 PolarHBondContact O-N 2.9Å; M141-V144 WeakPolarHBondContact O-CG2 3.5Å; M141-V144 PolarHBondContact O-N 2.89Å; M141-V144 HydrophobicContact SD-CG2 4.3Å; M141-M145 WeakPolarHBondContact O-CB 3.33Å; M141-M145 PolarHBondContact O-N 3.41Å; M141-I171 HydrophobicContact CE-CG2 4.46Å; M141-I171 HydrophobicContact SD-CG2 4.3Å; M141-A174 HydrophobicContact CE-CB 3.32Å; M141-W175 HydrophobicContact CE-CD2 4.4Å; M141-W175 HydrophobicContact CE-CG 4.08Å
142	L	94.8	Very high	94.1	Very high	0 Å²	0	12.5 Å²	12.5	0%	0	6%	0.063	C	C	.	.	H	α-helix	trans	-63.1	-41.9	174	-64.4	177.2	0	0	0	112.4	L93 S138 A139 Y140 M145 T146 I296 Y300	L93-L142 HydrophobicContact CD1-CD2 4.11Å; L93-L142 HydrophobicContact CD1-CG 4.43Å; L93-L142 HydrophobicContact CD2-CD2 3.67Å; S138-L142 WeakPolarHBondContact O-CG 3.32Å; S138-L142 PolarHBondContact O-N 3.49Å; S138-L142 VanDerWaalsContact O-N 3.17Å; A139-L142 WeakPolarHBondContact O-CB 3.39Å; A139-L142 PolarHBondContact O-N 2.97Å; Y140-L142 VanDerWaalsContact C-N 3.32Å; L142-M145 HydrophobicContact CD2-CE 3.73Å; L142-T146 WeakPolarHBondContact O-CB 3.5Å; L142-T146 PolarHBondContact O-N 2.95Å; L142-T146 PolarHBondContact O-OG1 2.65Å; L142-I296 HydrophobicContact CD2-CB 4.49Å; L142-I296 HydrophobicContact CD2-CG2 3.28Å; L142-Y300 HydrophobicContact CD1-CD1 4.31Å; L142-Y300 HydrophobicContact CD1-CD2 3.74Å; L142-Y300 HydrophobicContact CD1-CE2 4.5Å; L142-Y300 HydrophobicContact CD1-CG 3.64Å
143	V	97.1	Very high	93.7	Very high	17 Å²	17	13 Å²	13	10%	0.103	7%	0.066	C	C	.	.	H	α-helix	trans	-60.1	-52.1	176.8	171.6	0	0	0	0	110.5	A139 Y140 M145 T146 A147 P228 I231 L232	A139-V143 PolarHBondContact O-N 2.69Å; A139-V143 VanDerWaalsContact O-N 3.12Å; Y140-V143 PolarHBondContact O-N 3.38Å; V143-M145 PolarHBondContact O-N 3.08Å; V143-T146 PolarHBondContact O-N 3.27Å; V143-A147 WeakPolarHBondContact O-CB 3.38Å; V143-A147 PolarHBondContact O-N 3.24Å; V143-P228 HydrophobicContact CG2-CB 3.87Å; V143-P228 HydrophobicContact CG2-CG 4.35Å; V143-I231 HydrophobicContact CG1-CB 4.36Å; V143-I231 HydrophobicContact CG1-CD1 4.3Å; V143-I231 HydrophobicContact CG1-CG2 3.67Å; V143-L232 HydrophobicContact CG2-CD2 4.49Å; V143-L232 HydrophobicContact CG2-CG 4.36Å
144	V	95.9	Very high	93.2	Very high	19 Å²	19	12.4 Å²	12.4	12%	0.115	7%	0.066	C	C	.	.	H	α-helix	trans	-70	-33.2	-177.4	-62.7	0	0	0	0	113	F89 Y140 M141 A147 D148 M170 A174	F89-V144 HydrophobicContact CD1-CG2 4.39Å; F89-V144 HydrophobicContact CE1-CB 4.35Å; F89-V144 HydrophobicContact CE1-CG2 3.95Å; Y140-V144 WeakPolarHBondContact O-CG2 3.43Å; Y140-V144 PolarHBondContact O-N 3.17Å; M141-V144 WeakPolarHBondContact O-CG2 3.5Å; M141-V144 PolarHBondContact O-N 2.89Å; M141-V144 HydrophobicContact SD-CG2 4.3Å; V144-A147 PolarHBondContact O-N 3.1Å; V144-D148 PolarHBondContact O-N 3.4Å; V144-M170 HydrophobicContact CB-CB 4.15Å; V144-M170 HydrophobicContact CB-CE 4.09Å; V144-M170 HydrophobicContact CG1-CB 4.24Å; V144-M170 VanDerWaalsContact O-CE 3.25Å; V144-M170 WeakPolarHBondContact O-CE 3.5Å; V144-A174 HydrophobicContact CG1-CB 3.79Å; V144-A174 HydrophobicContact CG2-CB 4.22Å
145	M	93.2	Very high	92.7	Very high	1 Å²	1	15.8 Å²	15.8	1%	0.005	8%	0.081	C	C	.	.	H	α-helix	trans	-62.4	-45.4	172.5	-179.5	175.1	63	0	0	110.9	F89 L93 M141 L142 V143 D148 R149 T293 I296	F89-M145 HydrophobicContact CB-CB 4.47Å; F89-M145 HydrophobicContact CB-CG 4.2Å; F89-M145 HydrophobicContact CB-SD 4.42Å; F89-M145 HydrophobicContact CD1-CB 4.09Å; F89-M145 HydrophobicContact CG-CB 4.36Å; F89-M145 HydrophobicContact CG-CG 4.38Å; L93-M145 HydrophobicContact CD2-CE 3.62Å; L93-M145 HydrophobicContact CD2-SD 4.02Å; M141-M145 WeakPolarHBondContact O-CB 3.33Å; M141-M145 PolarHBondContact O-N 3.41Å; L142-M145 HydrophobicContact CD2-CE 3.73Å; V143-M145 PolarHBondContact O-N 3.08Å; M145-D148 PolarHBondContact O-N 2.85Å; M145-R149 WeakPolarHBondContact O-CG 3.23Å; M145-R149 PolarHBondContact O-N 3.22Å; M145-R149 VanDerWaalsContact O-N 3.1Å; M145-T293 HydrophobicContact CE-CG2 3.89Å; M145-T293 HydrophobicContact CG-CG2 3.86Å; M145-T293 HydrophobicContact SD-CG2 3.83Å; M145-I296 HydrophobicContact CE-CD1 3.97Å; M145-I296 HydrophobicContact CE-CG2 4.42Å
146	T	94.4	Very high	92	Very high	0 Å²	0	17.5 Å²	17.5	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-68.3	-40.7	177.4	-58.4	0	0	0	0	111.8	L142 V143 D148 R149 Y150 L232 C235 Y236	L142-T146 WeakPolarHBondContact O-CB 3.5Å; L142-T146 PolarHBondContact O-N 2.95Å; L142-T146 PolarHBondContact O-OG1 2.65Å; V143-T146 PolarHBondContact O-N 3.27Å; T146-D148 VanDerWaalsContact C-N 3.3Å; T146-D148 PolarHBondContact O-N 3.31Å; T146-R149 WeakPolarHBondContact O-CA 3.42Å; T146-R149 WeakPolarHBondContact O-CB 3.48Å; T146-R149 PolarHBondContact O-N 3.36Å; T146-R149 VanDerWaalsContact O-N 3.07Å; T146-Y150 PolarHBondContact O-N 2.74Å; T146-L232 VanDerWaalsContact CB-CD2 3.5Å; T146-L232 HydrophobicContact CG2-CD2 3.84Å; T146-L232 WeakPolarHBondContact OG1-CD2 3.48Å; T146-C235 HydrophobicContact CG2-CB 3.68Å; T146-Y236 HydrophobicContact CG2-CD2 4.04Å; T146-Y236 HydrophobicContact CG2-CE1 4.34Å; T146-Y236 HydrophobicContact CG2-CE2 3.53Å; T146-Y236 PolarHBondContact OG1-OH 3.35Å
147	A	93.7	Very high	90.8	Very high	21 Å²	21	23.1 Å²	23.1	17%	0.174	12%	0.123	C	C	.	.	H	α-helix	trans	-60.3	-39.4	173.9	0	0	0	0	0	111.5	V143 V144 R149 Y150 I151 M170	V143-A147 WeakPolarHBondContact O-CB 3.38Å; V143-A147 PolarHBondContact O-N 3.24Å; V144-A147 PolarHBondContact O-N 3.1Å; A147-R149 VanDerWaalsContact C-N 3.35Å; A147-R149 PolarHBondContact O-N 2.9Å; A147-Y150 WeakPolarHBondContact O-CB 3.46Å; A147-Y150 PolarHBondContact O-N 2.85Å; A147-I151 VanDerWaalsContact O-CG1 3.25Å; A147-I151 WeakPolarHBondContact O-CG1 3.38Å; A147-I151 PolarHBondContact O-N 3.39Å; A147-M170 HydrophobicContact CB-CE 3.63Å
148	D	91.2	Very high	89.4	Confident	0 Å²	0	30.1 Å²	30.1	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-64.5	-38.5	173.4	-179.7	71.6	0	0	0	112.1	R85 F89 V144 M145 T146 I151 A152 R166 M170	R85-D148 IonicContact NH1-OD1 3.21Å; R85-D148 PolarHBondContact NH1-OD1 3.43Å; R85-D148 IonicContact NH1-OD2 3.88Å; F89-D148 HydrophobicContact CE2-CB 3.59Å; F89-D148 VanDerWaalsContact CE2-CG 3.5Å; F89-D148 HydrophobicContact CZ-CB 3.59Å; V144-D148 PolarHBondContact O-N 3.4Å; M145-D148 PolarHBondContact O-N 2.85Å; T146-D148 VanDerWaalsContact C-N 3.3Å; T146-D148 PolarHBondContact O-N 3.31Å; D148-I151 PolarHBondContact O-N 3.17Å; D148-A152 WeakPolarHBondContact O-CB 3.4Å; D148-A152 PolarHBondContact O-N 3.22Å; D148-R166 IonicContact OD1-CZ 3.78Å; D148-R166 IonicContact OD1-NH2 2.77Å; D148-R166 PolarHBondContact OD1-NH2 3.06Å; D148-M170 HydrophobicContact CB-CE 4.37Å
149	R	90.7	Very high	88.1	Confident	21 Å²	21	30.6 Å²	30.6	8%	0.079	16%	0.156	C	C	.	.	H	α-helix	trans	-61.6	-46.3	172.6	-65	-53.5	89.2	175.4	9	111.5	M86 M145 T146 A147 I151 A152 V153 I239 T289 V290 T293	M86-R149 VanDerWaalsContact CE-NH1 3.31Å; M145-R149 WeakPolarHBondContact O-CG 3.23Å; M145-R149 PolarHBondContact O-N 3.22Å; M145-R149 VanDerWaalsContact O-N 3.1Å; T146-R149 WeakPolarHBondContact O-CA 3.42Å; T146-R149 WeakPolarHBondContact O-CB 3.48Å; T146-R149 PolarHBondContact O-N 3.36Å; T146-R149 VanDerWaalsContact O-N 3.07Å; A147-R149 VanDerWaalsContact C-N 3.35Å; A147-R149 PolarHBondContact O-N 2.9Å; R149-I151 PolarHBondContact O-N 3Å; R149-A152 PolarHBondContact O-N 3.33Å; R149-V153 WeakPolarHBondContact O-CG2 3.4Å; R149-V153 PolarHBondContact O-N 3.34Å; R149-I239 HydrophobicContact CB-CD1 4.23Å; R149-T289 PolarHBondContact NH1-OG1 3.44Å; R149-V290 HydrophobicContact CB-CG2 4.43Å; R149-T293 HydrophobicContact CG-CG2 3.88Å
150	Y	91.4	Very high	86.5	Confident	59 Å²	59	36.8 Å²	36.8	23%	0.231	19%	0.188	C	C	.	.	H	α-helix	trans	-55.6	-51.9	175.9	164.9	-103.6	0	0	0	110.9	T146 A147 A152 V153 C154 H155 F238 I239	T146-Y150 PolarHBondContact O-N 2.74Å; A147-Y150 WeakPolarHBondContact O-CB 3.46Å; A147-Y150 PolarHBondContact O-N 2.85Å; Y150-A152 VanDerWaalsContact C-N 3.33Å; Y150-A152 PolarHBondContact O-N 2.84Å; Y150-V153 PolarHBondContact O-N 2.64Å; Y150-C154 HydrophobicContact CD2-CB 4.1Å; Y150-C154 VanDerWaalsContact CD2-SG 3.56Å; Y150-C154 HydrophobicContact CE2-CB 3.84Å; Y150-C154 VanDerWaalsContact O-CB 3.31Å; Y150-C154 WeakPolarHBondContact O-CB 3.15Å; Y150-C154 PolarHBondContact O-N 3.15Å; Y150-H155 AromaticContact CZ-NE2 3.95Å; Y150-H155 PolarHBondContact OH-NE2 2.81Å; Y150-F238 HydrophobicContact CD2-CB 3.85Å; Y150-F238 HydrophobicContact CE2-CB 3.47Å; Y150-F238 VanDerWaalsContact CE2-CB 3.47Å; Y150-F238 HydrophobicContact CE2-CD2 4.1Å; Y150-F238 AromaticContact CE2-CG 3.93Å; Y150-F238 HydrophobicContact CE2-CG 3.93Å; Y150-I239 HydrophobicContact CD2-CG1 4.32Å
151	I	89.7	Confident	85	Confident	33 Å²	33	43.5 Å²	43.5	17%	0.169	22%	0.22	C	C	.	.	H	α-helix	trans	-64.6	-38.7	-179.7	-57.6	160.3	0	0	0	111.1	A147 D148 R149 V153 H155 T159	A147-I151 VanDerWaalsContact O-CG1 3.25Å; A147-I151 WeakPolarHBondContact O-CG1 3.38Å; A147-I151 PolarHBondContact O-N 3.39Å; D148-I151 PolarHBondContact O-N 3.17Å; R149-I151 PolarHBondContact O-N 3Å; I151-V153 VanDerWaalsContact C-N 3.3Å; I151-V153 PolarHBondContact O-N 3Å; I151-H155 HydrophobicContact CG2-CB 4.24Å; I151-H155 CarbonylContact O-C 3.45Å; I151-H155 WeakPolarHBondContact O-CA 3.23Å; I151-H155 PolarHBondContact O-N 3.15Å; I151-H155 VanDerWaalsContact O-O 3.04Å; I151-T159 PolarHBondContact O-OG1 2.92Å
152	A	86.7	Confident	83.7	Confident	8 Å²	8	48.8 Å²	48.8	7%	0.066	25%	0.245	C	C	.	.	H	α-helix	trans	-69.1	-24.9	-179.6	0	0	0	0	0	114.4	D148 R149 Y150 K286	D148-A152 WeakPolarHBondContact O-CB 3.4Å; D148-A152 PolarHBondContact O-N 3.22Å; R149-A152 PolarHBondContact O-N 3.33Å; Y150-A152 VanDerWaalsContact C-N 3.33Å; Y150-A152 PolarHBondContact O-N 2.84Å; A152-K286 PolarHBondContact O-NZ 3.37Å
153	V	86.2	Confident	82.8	Confident	10 Å²	10	50.9 Å²	50.9	6%	0.061	26%	0.259	C	S	.	.	H	α-helix	trans	-93.7	-54.1	178.2	174.9	0	0	0	0	111	R149 Y150 I151 I239 N242 I243 I282 V290	R149-V153 WeakPolarHBondContact O-CG2 3.4Å; R149-V153 PolarHBondContact O-N 3.34Å; Y150-V153 PolarHBondContact O-N 2.64Å; I151-V153 VanDerWaalsContact C-N 3.3Å; I151-V153 PolarHBondContact O-N 3Å; V153-I239 HydrophobicContact CG1-CG2 4.45Å; V153-N242 HydrophobicContact CG1-CB 4.49Å; V153-I243 HydrophobicContact CG1-CG1 4.36Å; V153-I282 HydrophobicContact CG1-CD1 4.04Å; V153-V290 HydrophobicContact CG2-CG2 3.81Å
154	C	86.5	Confident	82.1	Confident	19 Å²	19	52.7 Å²	52.7	13%	0.128	28%	0.276	C	S	.	.	H	α-helix	trans	-80.4	-27.6	-172.6	-61.2	0	0	0	0	113.3	Y150 P156	Y150-C154 HydrophobicContact CD2-CB 4.1Å; Y150-C154 VanDerWaalsContact CD2-SG 3.56Å; Y150-C154 HydrophobicContact CE2-CB 3.84Å; Y150-C154 VanDerWaalsContact O-CB 3.31Å; Y150-C154 WeakPolarHBondContact O-CB 3.15Å; Y150-C154 PolarHBondContact O-N 3.15Å; C154-P156 VanDerWaalsContact C-CD 3.5Å; C154-P156 WeakPolarHBondContact O-CD 3.41Å
155	H	84.4	Confident	81.6	Confident	71 Å²	71	59.8 Å²	59.8	33%	0.329	30%	0.3	S	S	.	.			trans	-129.5	67.2	-178.4	-56.8	-60.3	0	0	0	111.6	Y150 I151 L157 K158 T159	Y150-H155 AromaticContact CZ-NE2 3.95Å; Y150-H155 PolarHBondContact OH-NE2 2.81Å; I151-H155 HydrophobicContact CG2-CB 4.24Å; I151-H155 CarbonylContact O-C 3.45Å; I151-H155 WeakPolarHBondContact O-CA 3.23Å; I151-H155 PolarHBondContact O-N 3.15Å; I151-H155 VanDerWaalsContact O-O 3.04Å; H155-L157 VanDerWaalsContact C-N 3.25Å; H155-L157 PolarHBondContact O-N 2.88Å; H155-K158 HydrophobicContact CB-CB 4.07Å; H155-K158 HydrophobicContact CB-CD 4.27Å; H155-K158 HydrophobicContact CB-CG 4.27Å; H155-K158 PolarHBondContact O-N 3.03Å; H155-T159 PolarHBondContact O-N 2.54Å; H155-T159 PolarHBondContact O-OG1 2.82Å
156	P	77.7	Confident	81.5	Confident	50 Å²	50	62.1 Å²	62.1	33%	0.325	31%	0.309	S	S	.	.	T	Hydrogen-bonded Turn	trans	-59	-36.6	-176.5	23.7	-33.4	0	0	0	112.5	C154 T159	C154-P156 VanDerWaalsContact C-CD 3.5Å; C154-P156 WeakPolarHBondContact O-CD 3.41Å; P156-T159 WeakPolarHBondContact O-CB 3.48Å; P156-T159 PolarHBondContact O-N 3.39Å
157	L	72.6	Confident	81.3	Confident	118 Å²	118	62.1 Å²	62.1	62%	0.618	31%	0.309	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.2	-40.7	-179.5	-61.4	176.7	0	0	0	112.7	H155 T159 L160	H155-L157 VanDerWaalsContact C-N 3.25Å; H155-L157 PolarHBondContact O-N 2.88Å; L157-T159 PolarHBondContact O-N 2.93Å; L157-L160 HydrophobicContact CD2-CD1 4.09Å; L157-L160 WeakPolarHBondContact O-CB 3.45Å; L157-L160 PolarHBondContact O-N 3.34Å; L157-L160 VanDerWaalsContact O-N 3.13Å
158	K	67.5	Low	81.2	Confident	147 Å²	147	68.7 Å²	68.7	64%	0.639	33%	0.329	S	S	*	.	H	α-helix	trans	-63.5	-21.5	174.2	-71.6	-169.5	176.4	-176.8	0	112.8	H155 L160	H155-K158 HydrophobicContact CB-CB 4.07Å; H155-K158 HydrophobicContact CB-CD 4.27Å; H155-K158 HydrophobicContact CB-CG 4.27Å; H155-K158 PolarHBondContact O-N 3.03Å; K158-L160 VanDerWaalsContact C-N 3.34Å
159	T	66.7	Low	81.4	Confident	14 Å²	14	74.5 Å²	74.5	9%	0.086	36%	0.36	C	S	.	.	H	α-helix	trans	-80.7	-15.9	179.3	-62.4	0	0	0	0	112.9	I151 H155 P156 L157	I151-T159 PolarHBondContact O-OG1 2.92Å; H155-T159 PolarHBondContact O-N 2.54Å; H155-T159 PolarHBondContact O-OG1 2.82Å; P156-T159 WeakPolarHBondContact O-CB 3.48Å; P156-T159 PolarHBondContact O-N 3.39Å; L157-T159 PolarHBondContact O-N 2.93Å
160	L	63.4	Low	81.6	Confident	131 Å²	131	75 Å²	75	69%	0.686	36%	0.363	S	S	*	.	H	α-helix	trans	-76.4	-31.2	-178.1	-68.2	168.8	0	0	0	113	L157 K158	L157-L160 HydrophobicContact CD2-CD1 4.09Å; L157-L160 WeakPolarHBondContact O-CB 3.45Å; L157-L160 PolarHBondContact O-N 3.34Å; L157-L160 VanDerWaalsContact O-N 3.13Å; K158-L160 VanDerWaalsContact C-N 3.34Å
161	Q	64.5	Low	81.8	Confident	171 Å²	171	72.4 Å²	72.4	80%	0.799	35%	0.354	S	S	*	.	H	α-helix	trans	-78.9	-42.3	-167.1	-73.6	175.7	-30.4	0	0	113.9
162	Q	69.8	Low	82.2	Confident	115 Å²	115	73.2 Å²	73.2	54%	0.537	37%	0.365	S	S	.	.			trans	-154.3	69.4	177.8	-66.6	-168.8	-10.4	0	0	113.8	A164 R165 R166	Q162-A164 PolarHBondContact O-N 3.21Å; Q162-R165 HydrophobicContact CB-CB 4.49Å; Q162-R166 PolarHBondContact O-N 3Å
163	P	76.1	Confident	82.7	Confident	43 Å²	43	75.4 Å²	75.4	28%	0.279	38%	0.383	S	S	.	.	H	α-helix	trans	-64.7	-40.8	-171.8	22.5	-32.2	0	0	0	114.4	S167	P163-S167 PolarHBondContact O-N 3.03Å; P163-S167 PolarHBondContact O-OG 3.43Å
164	A	81.4	Confident	83.3	Confident	56 Å²	56	75 Å²	75	46%	0.463	38%	0.381	S	S	.	.	H	α-helix	trans	-78.2	-37.4	-173.5	0	0	0	0	0	113.4	Q162 R168	Q162-A164 PolarHBondContact O-N 3.21Å; A164-R168 WeakPolarHBondContact O-CG 3.42Å; A164-R168 PolarHBondContact O-N 3.05Å; A164-R168 VanDerWaalsContact O-N 3.1Å; A164-R168 PolarHBondContact O-NE 2.92Å
165	R	86.5	Confident	83.8	Confident	167 Å²	167	76.7 Å²	76.7	63%	0.63	39%	0.385	S	S	*	.	H	α-helix	trans	-65.1	-44.8	177.2	-172.5	-178.2	-178.8	-178.7	1.9	110.7	Q162 S167 R168 L169	Q162-R165 HydrophobicContact CB-CB 4.49Å; R165-S167 PolarHBondContact O-N 3.44Å; R165-R168 PolarHBondContact O-N 3.39Å; R165-L169 PolarHBondContact O-N 3.31Å
166	R	89.3	Confident	84.5	Confident	51 Å²	51	77.8 Å²	77.8	19%	0.192	40%	0.396	C	S	.	.	H	α-helix	trans	-57.2	-51.2	176.5	-172.3	-173.5	75.9	-158.7	9.3	111.7	D148 Q162 R168 L169 M170	D148-R166 IonicContact OD1-CZ 3.78Å; D148-R166 IonicContact OD1-NH2 2.77Å; D148-R166 PolarHBondContact OD1-NH2 3.06Å; Q162-R166 PolarHBondContact O-N 3Å; R166-R168 VanDerWaalsContact C-N 3.35Å; R166-R168 PolarHBondContact O-N 3.42Å; R166-L169 PolarHBondContact O-N 3.05Å; R166-M170 HydrophobicContact CG-CG 4.42Å; R166-M170 HydrophobicContact CG-SD 3.95Å; R166-M170 VanDerWaalsContact O-CG 3.29Å; R166-M170 WeakPolarHBondContact O-CG 3.38Å; R166-M170 PolarHBondContact O-N 2.91Å
167	S	91	Very high	85.4	Confident	0 Å²	0	79 Å²	79	0%	0	40%	0.399	C	S	.	.	H	α-helix	trans	-62.6	-40.3	-179.8	-65	0	0	0	0	112.9	R85 F89 P163 R165 L169 M170 I171	R85-S167 WeakPolarHBondContact CD-OG 3.35Å; R85-S167 VanDerWaalsContact CG-OG 3.28Å; R85-S167 WeakPolarHBondContact CG-OG 3.48Å; F89-S167 WeakPolarHBondContact CE2-OG 3.38Å; P163-S167 PolarHBondContact O-N 3.03Å; P163-S167 PolarHBondContact O-OG 3.43Å; R165-S167 PolarHBondContact O-N 3.44Å; S167-L169 VanDerWaalsContact C-N 3.34Å; S167-L169 PolarHBondContact O-N 3.39Å; S167-M170 PolarHBondContact O-N 3.3Å; S167-I171 WeakPolarHBondContact O-CB 3.33Å; S167-I171 WeakPolarHBondContact O-CD1 3.45Å; S167-I171 VanDerWaalsContact O-CG1 3.24Å; S167-I171 WeakPolarHBondContact O-CG1 3.36Å; S167-I171 PolarHBondContact O-N 3.1Å
168	R	92.5	Very high	86.6	Confident	158 Å²	158	73.3 Å²	73.3	60%	0.596	37%	0.37	S	S	*	.	H	α-helix	trans	-61.5	-42	174.7	-75.2	-174.6	-70.1	166	-2.6	112.1	L88 A164 R165 R166 I171 A172	L88-R168 HydrophobicContact CD2-CG 3.92Å; A164-R168 WeakPolarHBondContact O-CG 3.42Å; A164-R168 PolarHBondContact O-N 3.05Å; A164-R168 VanDerWaalsContact O-N 3.1Å; A164-R168 PolarHBondContact O-NE 2.92Å; R165-R168 PolarHBondContact O-N 3.39Å; R166-R168 VanDerWaalsContact C-N 3.35Å; R166-R168 PolarHBondContact O-N 3.42Å; R168-I171 PolarHBondContact O-N 3.48Å; R168-A172 WeakPolarHBondContact O-CB 3.25Å; R168-A172 PolarHBondContact O-N 3.11Å
169	L	93.9	Very high	88.1	Confident	122 Å²	122	71.3 Å²	71.3	64%	0.639	36%	0.361	S	S	*	.	H	α-helix	trans	-64.9	-44	176.6	-177.8	63.1	0	0	0	111.8	R165 R166 S167 I171 A172 A173	R165-L169 PolarHBondContact O-N 3.31Å; R166-L169 PolarHBondContact O-N 3.05Å; S167-L169 VanDerWaalsContact C-N 3.34Å; S167-L169 PolarHBondContact O-N 3.39Å; L169-I171 VanDerWaalsContact C-N 3.35Å; L169-I171 PolarHBondContact O-N 2.95Å; L169-A172 PolarHBondContact O-N 3.09Å; L169-A173 VanDerWaalsContact O-CB 3.31Å; L169-A173 WeakPolarHBondContact O-CB 3.45Å; L169-A173 PolarHBondContact O-N 2.93Å
170	M	95.1	Very high	89.5	Confident	32 Å²	32	74.3 Å²	74.3	16%	0.158	38%	0.379	C	S	.	.	H	α-helix	trans	-60.4	-44.5	176.6	-68.1	171	70.1	0	0	111.5	V144 A147 D148 R166 S167 A173 A174	V144-M170 HydrophobicContact CB-CB 4.15Å; V144-M170 HydrophobicContact CB-CE 4.09Å; V144-M170 HydrophobicContact CG1-CB 4.24Å; V144-M170 VanDerWaalsContact O-CE 3.25Å; V144-M170 WeakPolarHBondContact O-CE 3.5Å; A147-M170 HydrophobicContact CB-CE 3.63Å; D148-M170 HydrophobicContact CB-CE 4.37Å; R166-M170 HydrophobicContact CG-CG 4.42Å; R166-M170 HydrophobicContact CG-SD 3.95Å; R166-M170 VanDerWaalsContact O-CG 3.29Å; R166-M170 WeakPolarHBondContact O-CG 3.38Å; R166-M170 PolarHBondContact O-N 2.91Å; S167-M170 PolarHBondContact O-N 3.3Å; M170-A173 PolarHBondContact O-N 3.22Å; M170-A174 PolarHBondContact O-N 3.5Å
171	I	97	Very high	91.1	Very high	5 Å²	5	69.1 Å²	69.1	3%	0.026	35%	0.352	C	S	.	.	H	α-helix	trans	-62.4	-49.8	176.7	-70.2	164.9	0	0	0	110.4	L88 F89 H92 M141 S167 R168 L169 A173 A174 W175	L88-I171 HydrophobicContact CD2-CD1 3.83Å; L88-I171 HydrophobicContact CG-CD1 3.71Å; F89-I171 HydrophobicContact CD1-CD1 3.98Å; F89-I171 HydrophobicContact CD1-CG1 3.98Å; F89-I171 HydrophobicContact CE1-CD1 3.97Å; F89-I171 HydrophobicContact CE1-CG1 3.73Å; H92-I171 HydrophobicContact CB-CG2 4.16Å; M141-I171 HydrophobicContact CE-CG2 4.46Å; M141-I171 HydrophobicContact SD-CG2 4.3Å; S167-I171 WeakPolarHBondContact O-CB 3.33Å; S167-I171 WeakPolarHBondContact O-CD1 3.45Å; S167-I171 VanDerWaalsContact O-CG1 3.24Å; S167-I171 WeakPolarHBondContact O-CG1 3.36Å; S167-I171 PolarHBondContact O-N 3.1Å; R168-I171 PolarHBondContact O-N 3.48Å; L169-I171 VanDerWaalsContact C-N 3.35Å; L169-I171 PolarHBondContact O-N 2.95Å; I171-A173 VanDerWaalsContact C-N 3.33Å; I171-A173 PolarHBondContact O-N 3.43Å; I171-A174 PolarHBondContact O-N 2.94Å; I171-W175 PolarHBondContact O-N 3.39Å
172	A	97.2	Very high	92.6	Very high	49 Å²	49	61 Å²	61	41%	0.405	31%	0.314	S	S	.	.	H	α-helix	trans	-58.6	-44.8	178.7	0	0	0	0	0	111.8	R168 L169 A174 W175 V176	R168-A172 WeakPolarHBondContact O-CB 3.25Å; R168-A172 PolarHBondContact O-N 3.11Å; L169-A172 PolarHBondContact O-N 3.09Å; A172-A174 VanDerWaalsContact C-N 3.32Å; A172-A174 PolarHBondContact O-N 2.89Å; A172-W175 PolarHBondContact O-N 2.93Å; A172-V176 WeakPolarHBondContact O-CG2 3.37Å; A172-V176 PolarHBondContact O-N 3.36Å
173	A	97.5	Very high	93.8	Very high	54 Å²	54	57.9 Å²	57.9	45%	0.446	30%	0.303	S	S	.	.	H	α-helix	trans	-59.5	-42	176.6	0	0	0	0	0	111.9	L169 M170 I171 V176 L177	L169-A173 VanDerWaalsContact O-CB 3.31Å; L169-A173 WeakPolarHBondContact O-CB 3.45Å; L169-A173 PolarHBondContact O-N 2.93Å; M170-A173 PolarHBondContact O-N 3.22Å; I171-A173 VanDerWaalsContact C-N 3.33Å; I171-A173 PolarHBondContact O-N 3.43Å; A173-V176 PolarHBondContact O-N 3.46Å; A173-L177 WeakPolarHBondContact O-CB 3.35Å; A173-L177 PolarHBondContact O-N 2.94Å
174	A	98	Very high	94.7	Very high	3 Å²	3	57.6 Å²	57.6	3%	0.025	30%	0.301	C	S	.	.	H	α-helix	trans	-67.8	-38.2	178.1	0	0	0	0	0	113	M141 V144 M170 I171 A172 S178	M141-A174 HydrophobicContact CE-CB 3.32Å; V144-A174 HydrophobicContact CG1-CB 3.79Å; V144-A174 HydrophobicContact CG2-CB 4.22Å; M170-A174 PolarHBondContact O-N 3.5Å; I171-A174 PolarHBondContact O-N 2.94Å; A172-A174 VanDerWaalsContact C-N 3.32Å; A172-A174 PolarHBondContact O-N 2.89Å; A174-S178 VanDerWaalsContact O-CB 3.3Å; A174-S178 WeakPolarHBondContact O-CB 3.48Å; A174-S178 PolarHBondContact O-N 3.47Å; A174-S178 PolarHBondContact O-OG 2.97Å
175	W	98.4	Very high	95.3	Very high	54 Å²	54	54.9 Å²	54.9	21%	0.205	28%	0.279	C	S	.	.	H	α-helix	trans	-64.6	-47.1	172.9	-78.7	103.4	0	0	0	112.4	H92 L95 A96 F133 A137 M141 I171 A172 S178 F179	H92-W175 AromaticContact ND1-NE1 3.34Å; H92-W175 PolarHBondContact ND1-NE1 2.69Å; L95-W175 HydrophobicContact CB-CZ2 4.38Å; A96-W175 HydrophobicContact CB-CH2 4.2Å; A96-W175 HydrophobicContact CB-CZ2 4.34Å; F133-W175 HydrophobicContact CE1-CE3 4.23Å; F133-W175 AromaticContact CE1-CZ3 3.75Å; F133-W175 HydrophobicContact CE1-CZ3 3.75Å; F133-W175 AromaticContact CE2-CE3 3.93Å; F133-W175 HydrophobicContact CE2-CE3 3.93Å; F133-W175 HydrophobicContact CE2-CZ3 4.24Å; F133-W175 AromaticContact CZ-CE3 3.38Å; F133-W175 HydrophobicContact CZ-CE3 3.38Å; F133-W175 AromaticContact CZ-CZ3 3.37Å; F133-W175 HydrophobicContact CZ-CZ3 3.37Å; A137-W175 HydrophobicContact CB-CE3 4.09Å; A137-W175 HydrophobicContact CB-CH2 4.24Å; A137-W175 HydrophobicContact CB-CZ3 3.77Å; M141-W175 HydrophobicContact CE-CD2 4.4Å; M141-W175 HydrophobicContact CE-CG 4.08Å; I171-W175 PolarHBondContact O-N 3.39Å; A172-W175 PolarHBondContact O-N 2.93Å; W175-S178 PolarHBondContact O-N 2.86Å; W175-F179 PolarHBondContact O-N 3.43Å
176	V	98.2	Very high	95.6	Very high	93 Å²	93	50.9 Å²	50.9	56%	0.564	27%	0.265	S	S	*	.	H	α-helix	trans	-62.1	-46.7	178.3	171.6	0	0	0	0	110.7	A172 A173 S178 F179 V180	A172-V176 WeakPolarHBondContact O-CG2 3.37Å; A172-V176 PolarHBondContact O-N 3.36Å; A173-V176 PolarHBondContact O-N 3.46Å; V176-S178 VanDerWaalsContact C-N 3.3Å; V176-S178 PolarHBondContact O-N 3.09Å; V176-F179 PolarHBondContact O-N 3Å; V176-V180 HydrophobicContact CG1-CG2 4.43Å; V176-V180 WeakPolarHBondContact O-CG2 3.39Å; V176-V180 PolarHBondContact O-N 3.14Å
177	L	97.5	Very high	95.8	Very high	75 Å²	75	56.4 Å²	56.4	39%	0.393	29%	0.29	S	S	.	.	H	α-helix	trans	-62.2	-40.3	178.2	-175.3	56	0	0	0	111.3	Y140 A173 F179 V180 L181	Y140-L177 HydrophobicContact CD1-CD2 3.69Å; Y140-L177 HydrophobicContact CD1-CG 4.2Å; Y140-L177 HydrophobicContact CE1-CD2 3.37Å; Y140-L177 HydrophobicContact CE1-CG 3.91Å; A173-L177 WeakPolarHBondContact O-CB 3.35Å; A173-L177 PolarHBondContact O-N 2.94Å; L177-F179 PolarHBondContact O-N 3.41Å; L177-V180 PolarHBondContact O-N 3.44Å; L177-L181 HydrophobicContact CD1-CD1 3.83Å; L177-L181 HydrophobicContact CD1-CD2 4.35Å; L177-L181 HydrophobicContact CD1-CG 3.87Å; L177-L181 HydrophobicContact CG-CD1 3.76Å; L177-L181 HydrophobicContact CG-CG 4.24Å; L177-L181 WeakPolarHBondContact O-CB 3.09Å; L177-L181 WeakPolarHBondContact O-CG 3.39Å; L177-L181 PolarHBondContact O-N 2.79Å
178	S	98.1	Very high	95.9	Very high	0 Å²	0	57.3 Å²	57.3	0%	0	30%	0.296	C	S	.	.	H	α-helix	trans	-62.8	-41.4	176.2	-58.5	0	0	0	0	112.4	F136 A137 A174 W175 V176 S182	F136-S178 VanDerWaalsContact C-OG 3.26Å; F136-S178 PolarHBondContact O-OG 3.34Å; A137-S178 VanDerWaalsContact CA-OG 3.28Å; A137-S178 WeakPolarHBondContact CA-OG 3.47Å; A137-S178 PolarHBondContact N-OG 3.45Å; A174-S178 VanDerWaalsContact O-CB 3.3Å; A174-S178 WeakPolarHBondContact O-CB 3.48Å; A174-S178 PolarHBondContact O-N 3.47Å; A174-S178 PolarHBondContact O-OG 2.97Å; W175-S178 PolarHBondContact O-N 2.86Å; V176-S178 VanDerWaalsContact C-N 3.3Å; V176-S178 PolarHBondContact O-N 3.09Å; S178-S182 WeakPolarHBondContact O-CB 3.31Å; S178-S182 PolarHBondContact O-N 2.78Å; S178-S182 PolarHBondContact O-OG 2.99Å; S178-S182 VanDerWaalsContact O-OG 3.08Å
179	F	97.5	Very high	95.9	Very high	105 Å²	105	49.9 Å²	49.9	46%	0.461	27%	0.268	S	S	.	.	H	α-helix	trans	-64.6	-43.6	175.6	-177.9	-95.7	0	0	0	112	H129 F133 W175 V176 L177 S182 T183	H129-F179 AromaticContact NE2-CD2 3.57Å; H129-F179 AromaticContact NE2-CE2 3.37Å; H129-F179 WeakPolarHBondContact NE2-CE2 3.38Å; F133-F179 HydrophobicContact CD2-CB 4.17Å; F133-F179 HydrophobicContact CE2-CB 3.99Å; F133-F179 HydrophobicContact CE2-CD2 4.5Å; W175-F179 PolarHBondContact O-N 3.43Å; V176-F179 PolarHBondContact O-N 3Å; L177-F179 PolarHBondContact O-N 3.41Å; F179-S182 PolarHBondContact O-N 2.91Å; F179-S182 PolarHBondContact O-OG 3.47Å; F179-T183 WeakPolarHBondContact O-CG2 3.35Å; F179-T183 PolarHBondContact O-N 3.29Å
180	V	97.4	Very high	95.9	Very high	76 Å²	76	44.7 Å²	44.7	46%	0.461	24%	0.242	S	C	.	.	H	α-helix	trans	-65.8	-47.2	178.9	172	0	0	0	0	111.1	V176 L177 S182 T183	V176-V180 HydrophobicContact CG1-CG2 4.43Å; V176-V180 WeakPolarHBondContact O-CG2 3.39Å; V176-V180 PolarHBondContact O-N 3.14Å; L177-V180 PolarHBondContact O-N 3.44Å; V180-S182 PolarHBondContact O-N 2.95Å; V180-T183 WeakPolarHBondContact O-CB 3.26Å; V180-T183 WeakPolarHBondContact O-CG2 3.22Å; V180-T183 PolarHBondContact O-N 3.28Å; V180-T183 VanDerWaalsContact O-N 3.1Å; V180-T183 PolarHBondContact O-OG1 3.03Å
181	L	97	Very high	95.8	Very high	22 Å²	22	45 Å²	45	12%	0.115	24%	0.243	C	C	.	.	H	α-helix	trans	-67.4	-21.1	-178.8	-66	173.8	0	0	0	113.3	F136 Y140 L177 P184 W219	F136-L181 HydrophobicContact CD1-CB 3.97Å; F136-L181 HydrophobicContact CD1-CD1 3.79Å; F136-L181 HydrophobicContact CD2-CB 4.21Å; F136-L181 HydrophobicContact CE1-CB 3.74Å; F136-L181 HydrophobicContact CE1-CD1 3.64Å; F136-L181 HydrophobicContact CE1-CG 4.29Å; F136-L181 HydrophobicContact CE2-CB 3.98Å; F136-L181 HydrophobicContact CG-CB 4.23Å; F136-L181 HydrophobicContact CZ-CB 3.75Å; F136-L181 HydrophobicContact CZ-CD1 4.43Å; Y140-L181 HydrophobicContact CE1-CD1 4.12Å; Y140-L181 HydrophobicContact CE2-CD1 4.31Å; Y140-L181 WeakPolarHBondContact OH-CD1 3.37Å; L177-L181 HydrophobicContact CD1-CD1 3.83Å; L177-L181 HydrophobicContact CD1-CD2 4.35Å; L177-L181 HydrophobicContact CD1-CG 3.87Å; L177-L181 HydrophobicContact CG-CD1 3.76Å; L177-L181 HydrophobicContact CG-CG 4.24Å; L177-L181 WeakPolarHBondContact O-CB 3.09Å; L177-L181 WeakPolarHBondContact O-CG 3.39Å; L177-L181 PolarHBondContact O-N 2.79Å; L181-P184 VanDerWaalsContact O-CD 3.28Å; L181-P184 WeakPolarHBondContact O-CD 3.45Å; L181-W219 HydrophobicContact CB-CZ2 4.33Å; L181-W219 HydrophobicContact CD2-CH2 3.44Å; L181-W219 VanDerWaalsContact CD2-CH2 3.44Å; L181-W219 HydrophobicContact CD2-CZ2 3.41Å; L181-W219 VanDerWaalsContact CD2-CZ2 3.41Å; L181-W219 HydrophobicContact CG-CZ2 4.46Å
182	S	96.2	Very high	95.4	Very high	0 Å²	0	46.8 Å²	46.8	0%	0	25%	0.253	C	S	.	.	T	Hydrogen-bonded Turn	trans	-89.1	-3.1	174	67	0	0	0	0	114.2	H129 S178 F179 V180 Q185	H129-S182 PolarHBondContact CE1-OG 3.1Å; H129-S182 PolarHBondContact ND1-O 3.33Å; H129-S182 PolarHBondContact ND1-OG 2.93Å; S178-S182 WeakPolarHBondContact O-CB 3.31Å; S178-S182 PolarHBondContact O-N 2.78Å; S178-S182 PolarHBondContact O-OG 2.99Å; S178-S182 VanDerWaalsContact O-OG 3.08Å; F179-S182 PolarHBondContact O-N 2.91Å; F179-S182 PolarHBondContact O-OG 3.47Å; V180-S182 PolarHBondContact O-N 2.95Å; S182-Q185 WeakPolarHBondContact O-CG 3.19Å; S182-Q185 PolarHBondContact O-N 3.48Å
183	T	95.1	Very high	95	Very high	50 Å²	50	47.8 Å²	47.8	31%	0.307	25%	0.249	S	C	.	.	T	Hydrogen-bonded Turn	trans	-62.7	-30	177.6	58.8	0	0	0	0	115.9	F179 V180 Q185 Y186	F179-T183 WeakPolarHBondContact O-CG2 3.35Å; F179-T183 PolarHBondContact O-N 3.29Å; V180-T183 WeakPolarHBondContact O-CB 3.26Å; V180-T183 WeakPolarHBondContact O-CG2 3.22Å; V180-T183 PolarHBondContact O-N 3.28Å; V180-T183 VanDerWaalsContact O-N 3.1Å; V180-T183 PolarHBondContact O-OG1 3.03Å; T183-Q185 PolarHBondContact O-N 2.83Å; T183-Y186 WeakPolarHBondContact O-CD2 3.5Å; T183-Y186 PolarHBondContact O-N 3.49Å; T183-Y186 VanDerWaalsContact O-N 3.14Å
184	P	94	Very high	94.4	Very high	37 Å²	37	47.2 Å²	47.2	24%	0.24	24%	0.24	C	C	.	.	T	Hydrogen-bonded Turn	trans	-57.3	-21.3	-179.7	-28.2	37.3	0	0	0	114.4	L181 Y186 F187 V188	L181-P184 VanDerWaalsContact O-CD 3.28Å; L181-P184 WeakPolarHBondContact O-CD 3.45Å; P184-Y186 PolarHBondContact O-N 3.21Å; P184-F187 PolarHBondContact O-N 3.03Å; P184-V188 WeakPolarHBondContact O-CG2 3.3Å; P184-V188 PolarHBondContact O-N 3.14Å
185	Q	93.7	Very high	93.5	Very high	0 Å²	0	49.3 Å²	49.3	0%	0	25%	0.25	C	S	.	.	H	α-helix	trans	-57.2	-33	178.5	-56.2	-54.6	-54	0	0	113.1	K128 H129 V132 S182 T183 F187 F189 Y216	K128-Q185 HydrophobicContact CB-CB 4.3Å; H129-Q185 HydrophobicContact CB-CB 4.13Å; V132-Q185 HydrophobicContact CB-CG 3.9Å; V132-Q185 HydrophobicContact CG1-CG 4.33Å; V132-Q185 VanDerWaalsContact CG2-CD 3.42Å; V132-Q185 HydrophobicContact CG2-CG 3.77Å; S182-Q185 WeakPolarHBondContact O-CG 3.19Å; S182-Q185 PolarHBondContact O-N 3.48Å; T183-Q185 PolarHBondContact O-N 2.83Å; Q185-F187 PolarHBondContact O-N 3.2Å; Q185-F189 PolarHBondContact O-N 3.35Å; Q185-F189 VanDerWaalsContact O-N 3.07Å; Q185-Y216 VanDerWaalsContact NE2-CE2 3.33Å; Q185-Y216 PolarHBondContact NE2-OH 2.99Å; Q185-Y216 PolarHBondContact OE1-OH 3.01Å
186	Y	93.6	Very high	92.7	Very high	83 Å²	83	52.1 Å²	52.1	33%	0.325	27%	0.27	S	S	.	.	H	α-helix	trans	-66.5	-25.3	178	-71.6	-72.7	0	0	0	113.3	R125 V126 H129 T183 P184	R125-Y186 HydrophobicContact CB-CD1 3.85Å; R125-Y186 HydrophobicContact CB-CE1 4.27Å; R125-Y186 PolarHBondContact NH1-O 3.38Å; V126-Y186 HydrophobicContact CG2-CE1 4.21Å; H129-Y186 HydrophobicContact CB-CD2 4.49Å; H129-Y186 HydrophobicContact CB-CE1 4.41Å; H129-Y186 HydrophobicContact CB-CE2 3.86Å; H129-Y186 AromaticContact CD2-CE2 4Å; H129-Y186 PolarHBondContact CD2-OH 2.91Å; H129-Y186 AromaticContact CE1-CE2 3.8Å; H129-Y186 AromaticContact CG-CE2 3.46Å; H129-Y186 VanDerWaalsContact CG-CE2 3.46Å; H129-Y186 AromaticContact CG-CZ 3.7Å; H129-Y186 AromaticContact ND1-CD2 3.98Å; H129-Y186 AromaticContact ND1-CE2 3.35Å; H129-Y186 WeakPolarHBondContact ND1-CE2 3.48Å; T183-Y186 WeakPolarHBondContact O-CD2 3.5Å; T183-Y186 PolarHBondContact O-N 3.49Å; T183-Y186 VanDerWaalsContact O-N 3.14Å; P184-Y186 PolarHBondContact O-N 3.21Å
187	F	92.6	Very high	91.9	Very high	166 Å²	166	53.2 Å²	53.2	73%	0.728	28%	0.276	S	S	*	.	H	α-helix	trans	-98.9	-28.7	-179.2	-54.5	-74.2	0	0	0	112.3	P184 Q185	P184-F187 PolarHBondContact O-N 3.03Å; Q185-F187 PolarHBondContact O-N 3.2Å
188	V	92.7	Very high	91.3	Very high	20 Å²	20	53.9 Å²	53.9	12%	0.121	28%	0.283	C	S	.	.	H	α-helix	trans	-83.3	-40.5	-177.6	174.2	0	0	0	0	112	P184 A205 T206 F207 Y216	P184-V188 WeakPolarHBondContact O-CG2 3.3Å; P184-V188 PolarHBondContact O-N 3.14Å; V188-A205 HydrophobicContact CG1-CB 3.85Å; V188-A205 CarbonylContact O-C 3.17Å; V188-A205 VanDerWaalsContact O-CA 3.28Å; V188-A205 WeakPolarHBondContact O-CA 3.44Å; V188-T206 PolarHBondContact O-N 3.39Å; V188-T206 PolarHBondContact O-OG1 2.99Å; V188-F207 HydrophobicContact CG1-CE1 3.64Å; V188-F207 HydrophobicContact CG1-CZ 3.74Å; V188-F207 HydrophobicContact CG2-CE1 4.36Å; V188-Y216 HydrophobicContact CB-CE2 4.44Å; V188-Y216 HydrophobicContact CG1-CD2 4.11Å; V188-Y216 HydrophobicContact CG1-CE2 4.11Å; V188-Y216 HydrophobicContact CG2-CD2 4Å; V188-Y216 HydrophobicContact CG2-CE2 4.25Å
189	F	93.7	Very high	90.5	Very high	1 Å²	1	59.8 Å²	59.8	0%	0.004	31%	0.309	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-99.9	140.9	-174.9	-71.5	-91.9	0	0	0	112.4	M1 R125 K128 Q185 W204 A205 Y216	M1-F189 HydrophobicContact SD-CZ 4.43Å; R125-F189 WeakPolarHBondContact CG-O 3.41Å; R125-F189 PolarHBondContact NH1-O 3.03Å; R125-F189 VanDerWaalsContact NH1-O 3.15Å; K128-F189 HydrophobicContact CB-CB 4.15Å; K128-F189 HydrophobicContact CB-CD1 4.48Å; K128-F189 HydrophobicContact CB-CD2 3.99Å; K128-F189 HydrophobicContact CB-CG 3.94Å; K128-F189 HydrophobicContact CD-CD1 3.65Å; K128-F189 HydrophobicContact CD-CD2 4.38Å; K128-F189 HydrophobicContact CD-CE1 3.73Å; K128-F189 HydrophobicContact CD-CE2 4.47Å; K128-F189 HydrophobicContact CD-CG 3.99Å; K128-F189 HydrophobicContact CD-CZ 4.16Å; K128-F189 HydrophobicContact CG-CB 3.85Å; K128-F189 HydrophobicContact CG-CD1 3.69Å; K128-F189 HydrophobicContact CG-CD2 4.09Å; K128-F189 HydrophobicContact CG-CE1 4.26Å; K128-F189 HydrophobicContact CG-CG 3.58Å; Q185-F189 PolarHBondContact O-N 3.35Å; Q185-F189 VanDerWaalsContact O-N 3.07Å; F189-W204 WeakPolarHBondContact CA-O 3.04Å; F189-A205 HydrophobicContact CD1-CB 4.11Å; F189-A205 HydrophobicContact CE1-CB 3.75Å; F189-A205 HydrophobicContact CE2-CB 4.46Å; F189-A205 HydrophobicContact CZ-CB 3.95Å; F189-Y216 HydrophobicContact CE2-CE2 4.4Å; F189-Y216 AromaticContact CE2-CZ 3.92Å
190	S	93.3	Very high	89.9	Confident	13 Å²	13	56 Å²	56	9%	0.091	30%	0.298	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-154.8	162.4	174.2	60.7	0	0	0	0	111.1	D121 R125 W204	D121-S190 WeakPolarHBondContact OD1-CA 3.45Å; R125-S190 VanDerWaalsContact NH2-CB 3.3Å; S190-W204 PolarHBondContact N-O 2.81Å; S190-W204 PolarHBondContact O-N 3.4Å; S190-W204 VanDerWaalsContact O-O 3.14Å
191	M	92.4	Very high	89.5	Confident	39 Å²	39	59.6 Å²	59.6	19%	0.192	30%	0.303	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-79	118.3	170.8	-76.8	-66.9	-69.5	0	0	110.1	F117 D121 C124 R201 D202 C203	F117-M191 HydrophobicContact CB-SD 4.4Å; F117-M191 HydrophobicContact CD1-CE 4.29Å; F117-M191 HydrophobicContact CD1-SD 3.58Å; F117-M191 VanDerWaalsContact CD1-SD 3.58Å; F117-M191 HydrophobicContact CE1-SD 4.32Å; F117-M191 HydrophobicContact CG-SD 4.38Å; D121-M191 HydrophobicContact CB-CB 4.1Å; D121-M191 HydrophobicContact CB-CG 4.18Å; D121-M191 PolarHBondContact OD1-N 3.47Å; C124-M191 HydrophobicContact CB-CG 3.84Å; C124-M191 HydrophobicContact CB-SD 4.09Å; M191-R201 HydrophobicContact CE-CB 3.78Å; M191-D202 WeakPolarHBondContact CA-O 3.21Å; M191-D202 VanDerWaalsContact SD-C 3.51Å; M191-C203 HydrophobicContact SD-CB 3.61Å; M191-C203 PolarHBondContact SD-N 3.27Å
192	I	89.8	Confident	89.2	Confident	43 Å²	43	59.2 Å²	59.2	22%	0.221	30%	0.301	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-122.6	159.6	178.6	68.7	169.4	0	0	0	111.3	V194 R201 D202 W204 T206	I192-V194 HydrophobicContact CD1-CG1 4.19Å; I192-V194 HydrophobicContact CG1-CG1 3.92Å; I192-R201 CarbonylContact O-C 3.49Å; I192-R201 WeakPolarHBondContact O-CA 3.44Å; I192-D202 PolarHBondContact N-O 3.47Å; I192-D202 PolarHBondContact O-N 3.17Å; I192-W204 HydrophobicContact CD1-CB 3.45Å; I192-W204 VanDerWaalsContact CD1-CB 3.45Å; I192-W204 HydrophobicContact CD1-CD2 4.09Å; I192-W204 HydrophobicContact CD1-CE3 4.04Å; I192-W204 HydrophobicContact CD1-CG 3.81Å; I192-W204 HydrophobicContact CG1-CB 3.51Å; I192-W204 HydrophobicContact CG1-CG 4.25Å; I192-T206 HydrophobicContact CG2-CG2 3.83Å
193	E	88.7	Confident	89	Confident	70 Å²	70	59.4 Å²	59.4	33%	0.327	30%	0.302	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-80.6	115.1	169	-71.9	177.5	-168.1	0	0	108.8	K199 R201	E193-K199 WeakPolarHBondContact OE2-CD 3.34Å; E193-K199 IonicContact OE2-NZ 3.02Å; E193-K199 PolarHBondContact OE2-NZ 3.49Å; E193-R201 HydrophobicContact CG-CG 3.66Å; E193-R201 IonicContact OE1-CZ 2.92Å; E193-R201 IonicContact OE1-NE 3.71Å; E193-R201 PolarHBondContact OE1-NE 3.39Å; E193-R201 IonicContact OE1-NH2 3.87Å; E193-R201 PolarHBondContact OE1-NH2 3.49Å
194	V	84.2	Confident	88.7	Confident	42 Å²	42	58.7 Å²	58.7	26%	0.255	29%	0.294	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.7	-13.3	-177.1	-61.3	0	0	0	0	113.2	I192 A200 D202	I192-V194 HydrophobicContact CD1-CG1 4.19Å; I192-V194 HydrophobicContact CG1-CG1 3.92Å; V194-A200 WeakPolarHBondContact CG2-O 3.22Å; V194-A200 PolarHBondContact N-O 2.98Å; V194-D202 HydrophobicContact CG1-CB 3.8Å; V194-D202 HydrophobicContact CG2-CB 4.11Å
195	N	80.5	Confident	88.5	Confident	47 Å²	47	57 Å²	57	25%	0.251	28%	0.283	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-134.6	113.7	177.4	-175.8	-40.1	0	0	0	109.6	V197 T198 K199 A200	N195-V197 PolarHBondContact O-N 3Å; N195-V197 WeakPolarHBondContact OD1-CA 3.49Å; N195-V197 WeakPolarHBondContact OD1-CB 3.05Å; N195-V197 PolarHBondContact OD1-N 2.84Å; N195-T198 VanDerWaalsContact CB-OG1 3.28Å; N195-T198 WeakPolarHBondContact CB-OG1 3.25Å; N195-T198 PolarHBondContact ND2-OG1 2.71Å; N195-T198 PolarHBondContact OD1-N 2.88Å; N195-T198 PolarHBondContact OD1-OG1 3.31Å; N195-K199 VanDerWaalsContact O-CA 3.31Å; N195-K199 WeakPolarHBondContact O-CA 3.5Å; N195-K199 PolarHBondContact O-N 3.14Å; N195-A200 HydrophobicContact CB-CB 4.45Å
196	N	79.6	Confident	88.2	Confident	113 Å²	113	60 Å²	60	60%	0.604	30%	0.301	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.5	-26	-178	-74.9	-18.4	0	0	0	113.2
197	V	82.6	Confident	88	Confident	116 Å²	116	59 Å²	59	70%	0.703	30%	0.299	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82.4	-51.9	-179.4	-176.3	0	0	0	0	111	N195 K199	N195-V197 PolarHBondContact O-N 3Å; N195-V197 WeakPolarHBondContact OD1-CA 3.49Å; N195-V197 WeakPolarHBondContact OD1-CB 3.05Å; N195-V197 PolarHBondContact OD1-N 2.84Å; V197-K199 VanDerWaalsContact C-N 3.33Å
198	T	84	Confident	87.7	Confident	89 Å²	89	59 Å²	59	55%	0.546	31%	0.305	S	S	.	.	T	Hydrogen-bonded Turn	trans	-86.6	-6.1	-175.6	61	0	0	0	0	113.4	N195 A200	N195-T198 VanDerWaalsContact CB-OG1 3.28Å; N195-T198 WeakPolarHBondContact CB-OG1 3.25Å; N195-T198 PolarHBondContact ND2-OG1 2.71Å; N195-T198 PolarHBondContact OD1-N 2.88Å; N195-T198 PolarHBondContact OD1-OG1 3.31Å; T198-A200 PolarHBondContact O-N 2.92Å; T198-A200 VanDerWaalsContact O-N 3.08Å; T198-A200 WeakPolarHBondContact OG1-CB 3.48Å
199	K	82.9	Confident	87.5	Confident	123 Å²	123	62.6 Å²	62.6	54%	0.535	32%	0.32	S	S	.	.	T	Hydrogen-bonded Turn	trans	52.9	26.1	-172.6	-65.5	-57.5	-162	173.4	0	113.2	E193 N195 V197 R201	E193-K199 WeakPolarHBondContact OE2-CD 3.34Å; E193-K199 IonicContact OE2-NZ 3.02Å; E193-K199 PolarHBondContact OE2-NZ 3.49Å; N195-K199 VanDerWaalsContact O-CA 3.31Å; N195-K199 WeakPolarHBondContact O-CA 3.5Å; N195-K199 PolarHBondContact O-N 3.14Å; V197-K199 VanDerWaalsContact C-N 3.33Å; K199-R201 PolarHBondContact O-N 2.97Å
200	A	85	Confident	87.1	Confident	27 Å²	27	67.8 Å²	67.8	22%	0.223	35%	0.354	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-73	127.7	-177.7	0	0	0	0	0	110.2	V194 N195 T198	V194-A200 WeakPolarHBondContact CG2-O 3.22Å; V194-A200 PolarHBondContact N-O 2.98Å; N195-A200 HydrophobicContact CB-CB 4.45Å; T198-A200 PolarHBondContact O-N 2.92Å; T198-A200 VanDerWaalsContact O-N 3.08Å; T198-A200 WeakPolarHBondContact OG1-CB 3.48Å
201	R	87.9	Confident	86.9	Confident	150 Å²	150	74.5 Å²	74.5	57%	0.566	38%	0.377	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-98.6	146.8	179.9	-65.5	-179.1	178.9	167.8	0.3	111.7	M191 I192 E193 K199	M191-R201 HydrophobicContact CE-CB 3.78Å; I192-R201 CarbonylContact O-C 3.49Å; I192-R201 WeakPolarHBondContact O-CA 3.44Å; E193-R201 HydrophobicContact CG-CG 3.66Å; E193-R201 IonicContact OE1-CZ 2.92Å; E193-R201 IonicContact OE1-NE 3.71Å; E193-R201 PolarHBondContact OE1-NE 3.39Å; E193-R201 IonicContact OE1-NH2 3.87Å; E193-R201 PolarHBondContact OE1-NH2 3.49Å; K199-R201 PolarHBondContact O-N 2.97Å
202	D	90.2	Very high	86.8	Confident	14 Å²	14	73.1 Å²	73.1	8%	0.075	37%	0.373	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-148.2	160.4	175.8	-150.2	1.9	0	0	0	112.4	W111 R116 F117 M191 I192 V194 W204	W111-D202 VanDerWaalsContact CH2-OD1 3.24Å; W111-D202 WeakPolarHBondContact CH2-OD1 3.3Å; W111-D202 VanDerWaalsContact CZ2-CG 3.44Å; W111-D202 WeakPolarHBondContact CZ2-OD1 3.49Å; W111-D202 WeakPolarHBondContact CZ2-OD2 2.95Å; R116-D202 WeakPolarHBondContact CD-OD2 3.39Å; F117-D202 VanDerWaalsContact CB-OD1 3.28Å; F117-D202 WeakPolarHBondContact CB-OD1 3.4Å; F117-D202 PolarHBondContact N-OD1 3.27Å; M191-D202 WeakPolarHBondContact CA-O 3.21Å; M191-D202 VanDerWaalsContact SD-C 3.51Å; I192-D202 PolarHBondContact N-O 3.47Å; I192-D202 PolarHBondContact O-N 3.17Å; V194-D202 HydrophobicContact CG1-CB 3.8Å; V194-D202 HydrophobicContact CG2-CB 4.11Å; D202-W204 PolarHBondContact O-N 3.47Å
203	C	91.9	Very high	86.6	Confident	4 Å²	4	73 Å²	73	3%	0.027	38%	0.376	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-89.7	104.5	-175.9	168.5	0	0	0	0	111.6	W111 F117 C124 K128 M191	W111-C203 HydrophobicContact CH2-CB 3.48Å; W111-C203 VanDerWaalsContact CH2-CB 3.48Å; W111-C203 WeakPolarHBondContact CH2-O 3.37Å; W111-C203 HydrophobicContact CZ3-CB 3.69Å; F117-C203 HydrophobicContact CB-CB 3.86Å; F117-C203 HydrophobicContact CD1-CB 3.96Å; F117-C203 HydrophobicContact CD2-CB 4.37Å; F117-C203 HydrophobicContact CG-CB 3.8Å; C124-C203 HydrophobicContact CB-CB 3.52Å; C124-C203 WeakPolarHBondContact CB-SG 3.27Å; C124-C203 WeakPolarHBondContact SG-CB 3.49Å; C124-C203 CovalentContact SG-SG 2.01Å; C124-C203 PolarHBondContact SG-SG 3.39Å; K128-C203 VanDerWaalsContact CE-SG 3.52Å; M191-C203 HydrophobicContact SD-CB 3.61Å; M191-C203 PolarHBondContact SD-N 3.27Å
204	W	89	Confident	86.8	Confident	35 Å²	35	74.4 Å²	74.4	13%	0.133	38%	0.378	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-131.8	156	-159.4	-137	85	0	0	0	112.1	S4 F189 S190 I192 D202	S4-W204 VanDerWaalsContact C-CZ2 3.48Å; S4-W204 WeakPolarHBondContact O-CH2 3.31Å; S4-W204 WeakPolarHBondContact O-CZ2 3.39Å; S4-W204 VanDerWaalsContact O-CZ3 3.32Å; S4-W204 WeakPolarHBondContact O-CZ3 3.26Å; F189-W204 WeakPolarHBondContact CA-O 3.04Å; S190-W204 PolarHBondContact N-O 2.81Å; S190-W204 PolarHBondContact O-N 3.4Å; S190-W204 VanDerWaalsContact O-O 3.14Å; I192-W204 HydrophobicContact CD1-CB 3.45Å; I192-W204 VanDerWaalsContact CD1-CB 3.45Å; I192-W204 HydrophobicContact CD1-CD2 4.09Å; I192-W204 HydrophobicContact CD1-CE3 4.04Å; I192-W204 HydrophobicContact CD1-CG 3.81Å; I192-W204 HydrophobicContact CG1-CB 3.51Å; I192-W204 HydrophobicContact CG1-CG 4.25Å; D202-W204 PolarHBondContact O-N 3.47Å
205	A	89.6	Confident	87.2	Confident	1 Å²	1	74.6 Å²	74.6	1%	0.008	38%	0.384	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-91.3	114.1	-176.3	0	0	0	0	0	111.5	L3 V188 F189 F207	L3-A205 HydrophobicContact CD2-CB 3.55Å; V188-A205 HydrophobicContact CG1-CB 3.85Å; V188-A205 CarbonylContact O-C 3.17Å; V188-A205 VanDerWaalsContact O-CA 3.28Å; V188-A205 WeakPolarHBondContact O-CA 3.44Å; F189-A205 HydrophobicContact CD1-CB 4.11Å; F189-A205 HydrophobicContact CE1-CB 3.75Å; F189-A205 HydrophobicContact CE2-CB 4.46Å; F189-A205 HydrophobicContact CZ-CB 3.95Å; A205-F207 HydrophobicContact CB-CE2 3.79Å; A205-F207 HydrophobicContact CB-CZ 3.98Å
206	T	88.2	Confident	87.7	Confident	63 Å²	63	73 Å²	73	39%	0.387	38%	0.375	S	S	.	.			trans	-98.5	119.4	-179.4	52.3	0	0	0	0	111	V188 I192	V188-T206 PolarHBondContact O-N 3.39Å; V188-T206 PolarHBondContact O-OG1 2.99Å; I192-T206 HydrophobicContact CG2-CG2 3.83Å
207	F	88.4	Confident	88.3	Confident	63 Å²	63	67.8 Å²	67.8	28%	0.276	35%	0.347	S	S	.	.			trans	-113.2	120.8	176.2	-59.1	-72	0	0	0	110.1	L3 V188 A205 Q209 G212 Y216	L3-F207 HydrophobicContact CD2-CE2 4.08Å; L3-F207 HydrophobicContact CD2-CZ 4.19Å; V188-F207 HydrophobicContact CG1-CE1 3.64Å; V188-F207 HydrophobicContact CG1-CZ 3.74Å; V188-F207 HydrophobicContact CG2-CE1 4.36Å; A205-F207 HydrophobicContact CB-CE2 3.79Å; A205-F207 HydrophobicContact CB-CZ 3.98Å; F207-Q209 VanDerWaalsContact C-N 3.27Å; F207-Q209 PolarHBondContact O-N 2.86Å; F207-G212 VanDerWaalsContact CD1-C 3.4Å; F207-G212 WeakPolarHBondContact CE1-O 3.28Å; F207-Y216 HydrophobicContact CE1-CD2 4.45Å; F207-Y216 AromaticContact CE1-CG 4Å; F207-Y216 HydrophobicContact CE1-CG 4Å; F207-Y216 HydrophobicContact CZ-CD1 4.1Å; F207-Y216 AromaticContact CZ-CG 3.91Å; F207-Y216 HydrophobicContact CZ-CG 3.91Å
208	I	86.4	Confident	88.8	Confident	167 Å²	167	64.5 Å²	64.5	86%	0.856	33%	0.327	S	S	*	.	S	Bend	trans	-67.4	-33.4	177.9	-59.6	170	0	0	0	110.9
209	Q	89	Confident	89.4	Confident	94 Å²	94	65.7 Å²	65.7	44%	0.439	32%	0.322	S	S	.	.	S	Bend	trans	-112	145.5	-173.4	-65.1	-66.9	-27.8	0	0	110.7	F207 W211 G212	F207-Q209 VanDerWaalsContact C-N 3.27Å; F207-Q209 PolarHBondContact O-N 2.86Å; Q209-W211 HydrophobicContact CB-CD2 3.93Å; Q209-W211 VanDerWaalsContact CB-CE2 3.46Å; Q209-W211 HydrophobicContact CB-CG 4.21Å; Q209-W211 HydrophobicContact CB-CZ2 3.82Å; Q209-W211 HydrophobicContact CG-CZ2 3.71Å; Q209-W211 PolarHBondContact O-N 3.41Å; Q209-G212 WeakPolarHBondContact O-CA 3.46Å; Q209-G212 PolarHBondContact O-N 3.09Å
210	P	85.5	Confident	89.9	Confident	110 Å²	110	60.3 Å²	60.3	71%	0.714	30%	0.299	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.4	-26.5	-178.1	25.7	-34.8	0	0	0	112.9	G212	P210-G212 VanDerWaalsContact C-N 3.26Å; P210-G212 PolarHBondContact O-N 2.87Å
211	W	88.6	Confident	90.4	Very high	155 Å²	155	59.3 Å²	59.3	59%	0.587	29%	0.29	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80	-4.6	173.8	54.7	-100.8	0	0	0	113.4	Q209 S213 R214 A215	Q209-W211 HydrophobicContact CB-CD2 3.93Å; Q209-W211 VanDerWaalsContact CB-CE2 3.46Å; Q209-W211 HydrophobicContact CB-CG 4.21Å; Q209-W211 HydrophobicContact CB-CZ2 3.82Å; Q209-W211 HydrophobicContact CG-CZ2 3.71Å; Q209-W211 PolarHBondContact O-N 3.41Å; W211-S213 PolarHBondContact O-N 2.94Å; W211-R214 WeakPolarHBondContact O-CB 3.46Å; W211-R214 PolarHBondContact O-N 3.43Å; W211-A215 HydrophobicContact CE3-CB 3.83Å; W211-A215 HydrophobicContact CZ3-CB 4.05Å; W211-A215 WeakPolarHBondContact O-CB 3.43Å; W211-A215 PolarHBondContact O-N 3Å
212	G	90.1	Very high	90.8	Very high	9 Å²	9	53.5 Å²	53.5	9%	0.093	28%	0.276	C	S	.	.	H	α-helix	trans	-62.2	-42.7	-174.3	0	0	0	0	0	113.4	F207 Q209 P210 A215 Y216	F207-G212 VanDerWaalsContact CD1-C 3.4Å; F207-G212 WeakPolarHBondContact CE1-O 3.28Å; Q209-G212 WeakPolarHBondContact O-CA 3.46Å; Q209-G212 PolarHBondContact O-N 3.09Å; P210-G212 VanDerWaalsContact C-N 3.26Å; P210-G212 PolarHBondContact O-N 2.87Å; G212-A215 PolarHBondContact O-N 3.35Å; G212-Y216 VanDerWaalsContact O-CB 3.25Å; G212-Y216 WeakPolarHBondContact O-CB 3.19Å; G212-Y216 PolarHBondContact O-N 2.95Å
213	S	87.2	Confident	91.1	Very high	41 Å²	41	53.3 Å²	53.3	29%	0.287	28%	0.278	S	S	.	.	H	α-helix	trans	-63.5	-42.5	175.4	58.2	0	0	0	0	111.7	W211 Y216 V217	W211-S213 PolarHBondContact O-N 2.94Å; S213-Y216 PolarHBondContact O-N 2.95Å; S213-V217 WeakPolarHBondContact O-CG2 3.45Å; S213-V217 PolarHBondContact O-N 3.47Å
214	R	91.2	Very high	91.2	Very high	100 Å²	100	53.2 Å²	53.2	38%	0.377	28%	0.277	S	S	.	.	H	α-helix	trans	-59.5	-49.8	174.4	-63.3	-177	174.4	160.1	5.4	112.3	W211 Y216 T218 V315 W316	W211-R214 WeakPolarHBondContact O-CB 3.46Å; W211-R214 PolarHBondContact O-N 3.43Å; R214-Y216 PolarHBondContact O-N 2.9Å; R214-T218 WeakPolarHBondContact O-CB 3.06Å; R214-T218 PolarHBondContact O-N 3.5Å; R214-T218 PolarHBondContact O-OG1 3.44Å; R214-V315 HydrophobicContact CB-CG1 3.9Å; R214-V315 HydrophobicContact CG-CG1 3.5Å; R214-V315 PolarHBondContact NE-O 3.42Å; R214-W316 HydrophobicContact CB-CZ2 4.42Å
215	A	92.7	Very high	91.6	Very high	46 Å²	46	52.8 Å²	52.8	38%	0.38	28%	0.276	S	S	.	.	H	α-helix	trans	-62.3	-43.6	177.4	0	0	0	0	0	111.5	W211 G212 T218 W219	W211-A215 HydrophobicContact CE3-CB 3.83Å; W211-A215 HydrophobicContact CZ3-CB 4.05Å; W211-A215 WeakPolarHBondContact O-CB 3.43Å; W211-A215 PolarHBondContact O-N 3Å; G212-A215 PolarHBondContact O-N 3.35Å; A215-T218 PolarHBondContact O-N 3.4Å; A215-W219 VanDerWaalsContact O-CB 3.23Å; A215-W219 WeakPolarHBondContact O-CB 3.33Å; A215-W219 PolarHBondContact O-N 3.3Å
216	Y	92.4	Very high	91.9	Very high	13 Å²	13	56 Å²	56	5%	0.051	30%	0.295	C	S	.	.	H	α-helix	trans	-63.9	-50.9	-179.5	178.3	-99.1	0	0	0	112.7	M1 L3 Q185 V188 F189 F207 G212 S213 R214 T218 W219 M220	M1-Y216 HydrophobicContact SD-CE1 3.88Å; M1-Y216 PolarHBondContact SD-OH 3.45Å; L3-Y216 HydrophobicContact CD1-CD1 3.92Å; L3-Y216 HydrophobicContact CD1-CE1 4.13Å; L3-Y216 HydrophobicContact CD2-CD1 4.39Å; L3-Y216 HydrophobicContact CD2-CE1 4.36Å; Q185-Y216 VanDerWaalsContact NE2-CE2 3.33Å; Q185-Y216 PolarHBondContact NE2-OH 2.99Å; Q185-Y216 PolarHBondContact OE1-OH 3.01Å; V188-Y216 HydrophobicContact CB-CE2 4.44Å; V188-Y216 HydrophobicContact CG1-CD2 4.11Å; V188-Y216 HydrophobicContact CG1-CE2 4.11Å; V188-Y216 HydrophobicContact CG2-CD2 4Å; V188-Y216 HydrophobicContact CG2-CE2 4.25Å; F189-Y216 HydrophobicContact CE2-CE2 4.4Å; F189-Y216 AromaticContact CE2-CZ 3.92Å; F207-Y216 HydrophobicContact CE1-CD2 4.45Å; F207-Y216 AromaticContact CE1-CG 4Å; F207-Y216 HydrophobicContact CE1-CG 4Å; F207-Y216 HydrophobicContact CZ-CD1 4.1Å; F207-Y216 AromaticContact CZ-CG 3.91Å; F207-Y216 HydrophobicContact CZ-CG 3.91Å; G212-Y216 VanDerWaalsContact O-CB 3.25Å; G212-Y216 WeakPolarHBondContact O-CB 3.19Å; G212-Y216 PolarHBondContact O-N 2.95Å; S213-Y216 PolarHBondContact O-N 2.95Å; R214-Y216 PolarHBondContact O-N 2.9Å; Y216-T218 VanDerWaalsContact C-N 3.3Å; Y216-T218 PolarHBondContact O-N 2.93Å; Y216-W219 WeakPolarHBondContact O-CB 3.29Å; Y216-W219 PolarHBondContact O-N 2.88Å; Y216-M220 HydrophobicContact CD1-CG 4.41Å; Y216-M220 HydrophobicContact CE1-CG 3.98Å; Y216-M220 HydrophobicContact CE2-CG 4.1Å; Y216-M220 HydrophobicContact CE2-SD 4.46Å; Y216-M220 WeakPolarHBondContact O-CB 3.39Å; Y216-M220 VanDerWaalsContact O-CG 3.22Å; Y216-M220 WeakPolarHBondContact O-CG 3.4Å; Y216-M220 PolarHBondContact O-N 3.47Å
217	V	91.6	Very high	92.4	Very high	4 Å²	4	54.8 Å²	54.8	2%	0.024	29%	0.292	C	S	.	.	H	α-helix	trans	-66.1	-37	178.6	174.2	0	0	0	0	111	L3 S213 M220 T221 Q311 M312 V315	L3-V217 HydrophobicContact CD1-CG2 3.34Å; S213-V217 WeakPolarHBondContact O-CG2 3.45Å; S213-V217 PolarHBondContact O-N 3.47Å; V217-M220 PolarHBondContact O-N 2.87Å; V217-T221 WeakPolarHBondContact O-CB 3.4Å; V217-T221 PolarHBondContact O-N 3.27Å; V217-T221 PolarHBondContact O-OG1 3.42Å; V217-Q311 HydrophobicContact CG1-CB 4.06Å; V217-M312 HydrophobicContact CG1-SD 4.13Å; V217-V315 HydrophobicContact CB-CG1 4.34Å; V217-V315 HydrophobicContact CB-CG2 4.1Å; V217-V315 HydrophobicContact CG1-CB 4.5Å; V217-V315 HydrophobicContact CG1-CG2 4.11Å; V217-V315 HydrophobicContact CG2-CG2 3.92Å
218	T	94.1	Very high	92.8	Very high	46 Å²	46	51.8 Å²	51.8	28%	0.282	28%	0.279	S	S	.	.	H	α-helix	trans	-65.6	-43	176	-58.5	0	0	0	0	112.1	R214 A215 Y216 G222 M312 W316	R214-T218 WeakPolarHBondContact O-CB 3.06Å; R214-T218 PolarHBondContact O-N 3.5Å; R214-T218 PolarHBondContact O-OG1 3.44Å; A215-T218 PolarHBondContact O-N 3.4Å; Y216-T218 VanDerWaalsContact C-N 3.3Å; Y216-T218 PolarHBondContact O-N 2.93Å; T218-G222 WeakPolarHBondContact O-CA 3.35Å; T218-G222 PolarHBondContact O-N 3Å; T218-M312 HydrophobicContact CG2-CE 4.1Å; T218-W316 WeakPolarHBondContact OG1-CZ2 3.47Å; T218-W316 PolarHBondContact OG1-NE1 3.45Å; T218-W316 VanDerWaalsContact OG1-NE1 3.1Å
219	W	95.1	Very high	93.3	Very high	114 Å²	114	45.7 Å²	45.7	43%	0.432	25%	0.249	S	C	.	.	H	α-helix	trans	-58.9	-48.7	173.9	167.3	-99.4	0	0	0	111.6	L181 A215 Y216 G222 G223	L181-W219 HydrophobicContact CB-CZ2 4.33Å; L181-W219 HydrophobicContact CD2-CH2 3.44Å; L181-W219 VanDerWaalsContact CD2-CH2 3.44Å; L181-W219 HydrophobicContact CD2-CZ2 3.41Å; L181-W219 VanDerWaalsContact CD2-CZ2 3.41Å; L181-W219 HydrophobicContact CG-CZ2 4.46Å; A215-W219 VanDerWaalsContact O-CB 3.23Å; A215-W219 WeakPolarHBondContact O-CB 3.33Å; A215-W219 PolarHBondContact O-N 3.3Å; Y216-W219 WeakPolarHBondContact O-CB 3.29Å; Y216-W219 PolarHBondContact O-N 2.88Å; W219-G222 PolarHBondContact O-N 3.33Å; W219-G223 PolarHBondContact O-N 3.35Å
220	M	93.9	Very high	93.7	Very high	11 Å²	11	45.4 Å²	45.4	5%	0.054	25%	0.254	C	S	.	.	H	α-helix	trans	-62.9	-47.6	-179.5	-72.4	-66.6	-68.5	0	0	111.6	M1 V132 F136 Y216 V217 I224	M1-M220 HydrophobicContact CE-CE 3.58Å; M1-M220 HydrophobicContact SD-CE 4.21Å; V132-M220 HydrophobicContact CB-CE 4.4Å; V132-M220 HydrophobicContact CG1-CE 3.78Å; V132-M220 HydrophobicContact CG1-SD 3.89Å; V132-M220 HydrophobicContact CG2-CE 3.77Å; F136-M220 HydrophobicContact CE2-SD 4.26Å; Y216-M220 HydrophobicContact CD1-CG 4.41Å; Y216-M220 HydrophobicContact CE1-CG 3.98Å; Y216-M220 HydrophobicContact CE2-CG 4.1Å; Y216-M220 HydrophobicContact CE2-SD 4.46Å; Y216-M220 WeakPolarHBondContact O-CB 3.39Å; Y216-M220 VanDerWaalsContact O-CG 3.22Å; Y216-M220 WeakPolarHBondContact O-CG 3.4Å; Y216-M220 PolarHBondContact O-N 3.47Å; V217-M220 PolarHBondContact O-N 2.87Å; M220-I224 HydrophobicContact CE-CD1 3.34Å; M220-I224 VanDerWaalsContact O-CB 3.27Å; M220-I224 WeakPolarHBondContact O-CB 3.18Å; M220-I224 WeakPolarHBondContact O-CG1 3.35Å; M220-I224 PolarHBondContact O-N 3.23Å; M220-I224 HydrophobicContact SD-CD1 4.11Å
221	T	95.1	Very high	94.2	Very high	6 Å²	6	43.5 Å²	43.5	4%	0.037	24%	0.237	C	C	.	.	H	α-helix	trans	-64.1	-43	176.4	-57.3	0	0	0	0	111.7	V217 F225 V226 F308 M312	V217-T221 WeakPolarHBondContact O-CB 3.4Å; V217-T221 PolarHBondContact O-N 3.27Å; V217-T221 PolarHBondContact O-OG1 3.42Å; T221-F225 WeakPolarHBondContact O-CA 3.42Å; T221-F225 WeakPolarHBondContact O-CB 3.35Å; T221-F225 PolarHBondContact O-N 3.45Å; T221-V226 HydrophobicContact CG2-CG2 4.03Å; T221-V226 PolarHBondContact O-N 2.86Å; T221-F308 HydrophobicContact CG2-CB 3.94Å; T221-F308 HydrophobicContact CG2-CD1 3.9Å; T221-F308 HydrophobicContact CG2-CG 4.17Å; T221-F308 WeakPolarHBondContact OG1-CD1 3.22Å; T221-M312 HydrophobicContact CG2-CE 3.6Å; T221-M312 HydrophobicContact CG2-CG 3.76Å; T221-M312 HydrophobicContact CG2-SD 4.12Å
222	G	96.8	Very high	94.6	Very high	27 Å²	27	36.1 Å²	36.1	28%	0.278	21%	0.209	S	C	.	.	I	π-helix	trans	-59.3	-49.9	177.4	0	0	0	0	0	112.2	T218 W219 A227	T218-G222 WeakPolarHBondContact O-CA 3.35Å; T218-G222 PolarHBondContact O-N 3Å; W219-G222 PolarHBondContact O-N 3.33Å; G222-A227 VanDerWaalsContact O-CB 3.27Å; G222-A227 WeakPolarHBondContact O-CB 3.46Å; G222-A227 PolarHBondContact O-N 3.21Å
223	G	96.1	Very high	94.8	Very high	11 Å²	11	38 Å²	38	11%	0.113	23%	0.228	C	C	.	.	I	π-helix	trans	-76.7	-42	-175.4	0	0	0	0	0	114.3	F136 Y140 W219 P228	F136-G223 VanDerWaalsContact CE1-C 3.48Å; Y140-G223 VanDerWaalsContact CE2-O 3.28Å; Y140-G223 WeakPolarHBondContact CE2-O 3.33Å; Y140-G223 PolarHBondContact OH-O 2.95Å; Y140-G223 VanDerWaalsContact OH-O 3.11Å; W219-G223 PolarHBondContact O-N 3.35Å; G223-P228 WeakPolarHBondContact O-CD 3.43Å
224	I	95.1	Very high	95.2	Very high	1 Å²	1	39.4 Å²	39.4	1%	0.005	24%	0.235	C	C	.	.	I	π-helix	trans	-88.9	-28.1	-173.2	-61.2	175.3	0	0	0	112	M135 F136 M220 P228 Y300 F308	M135-I224 HydrophobicContact CB-CD1 3.86Å; M135-I224 HydrophobicContact CB-CG2 4.21Å; M135-I224 HydrophobicContact CE-CD1 3.78Å; M135-I224 HydrophobicContact CE-CG2 4.01Å; M135-I224 HydrophobicContact SD-CD1 4.25Å; F136-I224 HydrophobicContact CD1-CG1 3.86Å; F136-I224 HydrophobicContact CD2-CD1 4.08Å; F136-I224 HydrophobicContact CD2-CG1 3.94Å; F136-I224 HydrophobicContact CE1-CG1 3.59Å; F136-I224 HydrophobicContact CE2-CD1 3.83Å; F136-I224 HydrophobicContact CE2-CG1 3.68Å; F136-I224 HydrophobicContact CG-CG1 4.02Å; F136-I224 HydrophobicContact CZ-CD1 4.1Å; F136-I224 HydrophobicContact CZ-CG1 3.49Å; F136-I224 VanDerWaalsContact CZ-CG1 3.49Å; M220-I224 HydrophobicContact CE-CD1 3.34Å; M220-I224 VanDerWaalsContact O-CB 3.27Å; M220-I224 WeakPolarHBondContact O-CB 3.18Å; M220-I224 WeakPolarHBondContact O-CG1 3.35Å; M220-I224 PolarHBondContact O-N 3.23Å; M220-I224 HydrophobicContact SD-CD1 4.11Å; I224-P228 WeakPolarHBondContact O-CG 3.18Å; I224-Y300 PolarHBondContact O-OH 3.36Å; I224-F308 HydrophobicContact CB-CE1 4.42Å; I224-F308 HydrophobicContact CB-CZ 3.8Å; I224-F308 HydrophobicContact CG2-CE2 4.04Å; I224-F308 HydrophobicContact CG2-CZ 3.57Å
225	F	95.9	Very high	95.4	Very high	26 Å²	26	35.3 Å²	35.3	11%	0.114	22%	0.221	C	C	.	.	I	π-helix	trans	-120.7	-61.8	-174	-176.2	-109.6	0	0	0	113.4	T221 A227 P228 V229 Y300 W304 A305 F308	T221-F225 WeakPolarHBondContact O-CA 3.42Å; T221-F225 WeakPolarHBondContact O-CB 3.35Å; T221-F225 PolarHBondContact O-N 3.45Å; F225-A227 PolarHBondContact O-N 2.68Å; F225-P228 WeakPolarHBondContact O-CD 3.26Å; F225-V229 HydrophobicContact CD2-CG2 3.88Å; F225-V229 HydrophobicContact CE1-CG2 4.42Å; F225-V229 HydrophobicContact CE2-CG2 3.66Å; F225-V229 HydrophobicContact CG-CG2 4.35Å; F225-V229 HydrophobicContact CZ-CG2 3.93Å; F225-V229 WeakPolarHBondContact O-CB 3.22Å; F225-V229 VanDerWaalsContact O-CG2 3.23Å; F225-V229 WeakPolarHBondContact O-CG2 3.4Å; F225-V229 PolarHBondContact O-N 3.01Å; F225-Y300 WeakPolarHBondContact CA-OH 3.4Å; F225-Y300 HydrophobicContact CD2-CE1 4.45Å; F225-W304 HydrophobicContact CD2-CB 4.02Å; F225-W304 HydrophobicContact CE2-CB 4.23Å; F225-A305 HydrophobicContact CE1-CB 4.44Å; F225-A305 HydrophobicContact CE2-CB 4Å; F225-A305 HydrophobicContact CZ-CB 3.55Å; F225-F308 HydrophobicContact CB-CB 4.38Å; F225-F308 HydrophobicContact CB-CD1 4.34Å; F225-F308 HydrophobicContact CB-CD2 3.39Å; F225-F308 HydrophobicContact CB-CE2 3.63Å; F225-F308 HydrophobicContact CB-CG 3.78Å; F225-F308 HydrophobicContact CB-CZ 4.2Å; F225-F308 HydrophobicContact CD1-CB 4.07Å; F225-F308 HydrophobicContact CD1-CD2 4.31Å; F225-F308 HydrophobicContact CD1-CG 4.38Å; F225-F308 AromaticContact CD2-CD2 3.83Å; F225-F308 HydrophobicContact CD2-CD2 3.83Å; F225-F308 HydrophobicContact CD2-CE2 4.35Å; F225-F308 HydrophobicContact CG-CB 4.21Å; F225-F308 AromaticContact CG-CD2 3.59Å; F225-F308 HydrophobicContact CG-CD2 3.59Å; F225-F308 HydrophobicContact CG-CE2 4.22Å; F225-F308 HydrophobicContact CG-CG 4.05Å
226	V	97.1	Very high	95.5	Very high	68 Å²	68	33.8 Å²	33.8	41%	0.412	21%	0.206	S	C	.	.	I	π-helix	trans	-62.3	-51.1	-170.5	178.1	0	0	0	0	111.7	T221 V229 V230	T221-V226 HydrophobicContact CG2-CG2 4.03Å; T221-V226 PolarHBondContact O-N 2.86Å; V226-V229 PolarHBondContact O-N 2.93Å; V226-V230 HydrophobicContact CG1-CG2 4.3Å; V226-V230 WeakPolarHBondContact O-CB 3.36Å; V226-V230 VanDerWaalsContact O-CG2 3.3Å; V226-V230 WeakPolarHBondContact O-CG2 3.28Å; V226-V230 PolarHBondContact O-N 3.44Å
227	A	97.1	Very high	95.6	Very high	38 Å²	38	35.1 Å²	35.1	31%	0.314	22%	0.224	S	C	.	.	H	α-helix	trans	-60.7	-49.7	179.4	0	0	0	0	0	112.1	G222 F225 V229 V230 I231	G222-A227 VanDerWaalsContact O-CB 3.27Å; G222-A227 WeakPolarHBondContact O-CB 3.46Å; G222-A227 PolarHBondContact O-N 3.21Å; F225-A227 PolarHBondContact O-N 2.68Å; A227-V229 PolarHBondContact O-N 3.45Å; A227-V230 PolarHBondContact O-N 2.96Å; A227-I231 WeakPolarHBondContact O-CD1 3.44Å; A227-I231 VanDerWaalsContact O-CG1 3.22Å; A227-I231 WeakPolarHBondContact O-CG1 3.48Å; A227-I231 PolarHBondContact O-N 3.32Å
228	P	97	Very high	95.7	Very high	1 Å²	1	40.5 Å²	40.5	1%	0.006	25%	0.247	C	C	.	.	H	α-helix	trans	-54.3	-49.3	171.1	-31.6	38.9	0	0	0	113.7	A139 Y140 V143 G223 I224 F225 V230 I231 L232 Y300	A139-P228 HydrophobicContact CB-CG 4.13Å; Y140-P228 HydrophobicContact CE2-CG 4.2Å; V143-P228 HydrophobicContact CG2-CB 3.87Å; V143-P228 HydrophobicContact CG2-CG 4.35Å; G223-P228 WeakPolarHBondContact O-CD 3.43Å; I224-P228 WeakPolarHBondContact O-CG 3.18Å; F225-P228 WeakPolarHBondContact O-CD 3.26Å; P228-V230 PolarHBondContact O-N 3.1Å; P228-I231 PolarHBondContact O-N 3.35Å; P228-L232 HydrophobicContact CB-CD1 4.46Å; P228-L232 VanDerWaalsContact O-CB 3.24Å; P228-L232 WeakPolarHBondContact O-CB 3.22Å; P228-L232 WeakPolarHBondContact O-CD1 3.39Å; P228-L232 WeakPolarHBondContact O-CG 3.47Å; P228-L232 PolarHBondContact O-N 3.18Å; P228-Y300 HydrophobicContact CB-CE1 4.43Å
229	V	96.9	Very high	95.6	Very high	38 Å²	38	38.3 Å²	38.3	23%	0.23	23%	0.234	C	C	.	.	H	α-helix	trans	-61.6	-42.7	-178.2	171.8	0	0	0	0	112.2	F225 V226 A227 L232 G233 Y300 I301	F225-V229 HydrophobicContact CD2-CG2 3.88Å; F225-V229 HydrophobicContact CE1-CG2 4.42Å; F225-V229 HydrophobicContact CE2-CG2 3.66Å; F225-V229 HydrophobicContact CG-CG2 4.35Å; F225-V229 HydrophobicContact CZ-CG2 3.93Å; F225-V229 WeakPolarHBondContact O-CB 3.22Å; F225-V229 VanDerWaalsContact O-CG2 3.23Å; F225-V229 WeakPolarHBondContact O-CG2 3.4Å; F225-V229 PolarHBondContact O-N 3.01Å; V226-V229 PolarHBondContact O-N 2.93Å; A227-V229 PolarHBondContact O-N 3.45Å; V229-L232 PolarHBondContact O-N 3.32Å; V229-G233 PolarHBondContact O-N 2.89Å; V229-Y300 HydrophobicContact CG2-CE1 4.05Å; V229-I301 HydrophobicContact CG1-CD1 4.41Å; V229-I301 HydrophobicContact CG2-CD1 4.48Å; V229-I301 HydrophobicContact CG2-CG1 3.97Å
230	V	97.2	Very high	95.4	Very high	88 Å²	88	36.3 Å²	36.3	53%	0.533	24%	0.236	S	C	.	.	H	α-helix	trans	-63.5	-45.6	176.5	171.5	0	0	0	0	111	V226 A227 P228 T234	V226-V230 HydrophobicContact CG1-CG2 4.3Å; V226-V230 WeakPolarHBondContact O-CB 3.36Å; V226-V230 VanDerWaalsContact O-CG2 3.3Å; V226-V230 WeakPolarHBondContact O-CG2 3.28Å; V226-V230 PolarHBondContact O-N 3.44Å; A227-V230 PolarHBondContact O-N 2.96Å; P228-V230 PolarHBondContact O-N 3.1Å; V230-T234 WeakPolarHBondContact O-CB 3.35Å; V230-T234 VanDerWaalsContact O-CG2 3.27Å; V230-T234 WeakPolarHBondContact O-CG2 3.37Å; V230-T234 PolarHBondContact O-N 3.41Å; V230-T234 PolarHBondContact O-OG1 3.09Å
231	I	97.2	Very high	95.3	Very high	70 Å²	70	42.9 Å²	42.9	36%	0.359	26%	0.261	S	S	.	.	H	α-helix	trans	-66.3	-41.7	179.1	-62.6	164.5	0	0	0	111	V143 A227 P228 T234 C235	V143-I231 HydrophobicContact CG1-CB 4.36Å; V143-I231 HydrophobicContact CG1-CD1 4.3Å; V143-I231 HydrophobicContact CG1-CG2 3.67Å; A227-I231 WeakPolarHBondContact O-CD1 3.44Å; A227-I231 VanDerWaalsContact O-CG1 3.22Å; A227-I231 WeakPolarHBondContact O-CG1 3.48Å; A227-I231 PolarHBondContact O-N 3.32Å; P228-I231 PolarHBondContact O-N 3.35Å; I231-T234 WeakPolarHBondContact CA-OG1 3.3Å; I231-T234 PolarHBondContact O-OG1 3.3Å; I231-C235 VanDerWaalsContact O-CB 3.31Å; I231-C235 WeakPolarHBondContact O-CB 3.31Å; I231-C235 PolarHBondContact O-N 3.48Å; I231-C235 PolarHBondContact O-SG 2.97Å
232	L	96.4	Very high	95	Very high	1 Å²	1	44.5 Å²	44.5	1%	0.005	27%	0.27	C	S	.	.	H	α-helix	trans	-65.7	-46.9	178.6	-69.6	171	0	0	0	111	V143 T146 P228 V229 C235 Y236 V297 Y300	V143-L232 HydrophobicContact CG2-CD2 4.49Å; V143-L232 HydrophobicContact CG2-CG 4.36Å; T146-L232 VanDerWaalsContact CB-CD2 3.5Å; T146-L232 HydrophobicContact CG2-CD2 3.84Å; T146-L232 WeakPolarHBondContact OG1-CD2 3.48Å; P228-L232 HydrophobicContact CB-CD1 4.46Å; P228-L232 VanDerWaalsContact O-CB 3.24Å; P228-L232 WeakPolarHBondContact O-CB 3.22Å; P228-L232 WeakPolarHBondContact O-CD1 3.39Å; P228-L232 WeakPolarHBondContact O-CG 3.47Å; P228-L232 PolarHBondContact O-N 3.18Å; V229-L232 PolarHBondContact O-N 3.32Å; L232-C235 PolarHBondContact O-N 3.28Å; L232-Y236 VanDerWaalsContact O-CD2 3.23Å; L232-Y236 WeakPolarHBondContact O-CD2 3.45Å; L232-Y236 PolarHBondContact O-N 3.21Å; L232-V297 HydrophobicContact CB-CG1 4.01Å; L232-V297 HydrophobicContact CD1-CG1 3.86Å; L232-V297 HydrophobicContact CD1-CG2 4.04Å; L232-V297 HydrophobicContact CD2-CG1 4.47Å; L232-V297 HydrophobicContact CD2-CG2 3.8Å; L232-V297 HydrophobicContact CG-CG1 4.33Å; L232-V297 HydrophobicContact CG-CG2 4.43Å; L232-Y300 HydrophobicContact CD1-CD1 4.34Å; L232-Y300 HydrophobicContact CD1-CE1 4.36Å
233	G	95.4	Very high	94.6	Very high	47 Å²	47	45.2 Å²	45.2	49%	0.485	27%	0.267	S	S	.	.	H	α-helix	trans	-59.7	-46.2	177.6	0	0	0	0	0	112.4	V229 G237	V229-G233 PolarHBondContact O-N 2.89Å; G233-G237 PolarHBondContact O-N 3.06Å
234	T	95.6	Very high	94.2	Very high	71 Å²	71	51.3 Å²	51.3	44%	0.436	29%	0.287	S	S	.	.	H	α-helix	trans	-64	-46.1	176.1	52.5	0	0	0	0	111.9	V230 I231 Y236 G237 F238	V230-T234 WeakPolarHBondContact O-CB 3.35Å; V230-T234 VanDerWaalsContact O-CG2 3.27Å; V230-T234 WeakPolarHBondContact O-CG2 3.37Å; V230-T234 PolarHBondContact O-N 3.41Å; V230-T234 PolarHBondContact O-OG1 3.09Å; I231-T234 WeakPolarHBondContact CA-OG1 3.3Å; I231-T234 PolarHBondContact O-OG1 3.3Å; T234-Y236 PolarHBondContact O-N 3.44Å; T234-G237 PolarHBondContact O-N 2.97Å; T234-F238 WeakPolarHBondContact O-CD2 3.46Å; T234-F238 PolarHBondContact O-N 3.17Å
235	C	95.6	Very high	93.8	Very high	14 Å²	14	53.4 Å²	53.4	10%	0.095	30%	0.301	C	S	.	.	H	α-helix	trans	-58.2	-48.7	176.7	-75	0	0	0	0	112.3	T146 I231 L232 F238 I239	T146-C235 HydrophobicContact CG2-CB 3.68Å; I231-C235 VanDerWaalsContact O-CB 3.31Å; I231-C235 WeakPolarHBondContact O-CB 3.31Å; I231-C235 PolarHBondContact O-N 3.48Å; I231-C235 PolarHBondContact O-SG 2.97Å; L232-C235 PolarHBondContact O-N 3.28Å; C235-F238 PolarHBondContact O-N 2.7Å; C235-I239 WeakPolarHBondContact O-CD1 3.25Å; C235-I239 WeakPolarHBondContact O-CG1 3.25Å; C235-I239 PolarHBondContact O-N 3.39Å
236	Y	94.3	Very high	93.2	Very high	14 Å²	14	53.5 Å²	53.5	6%	0.055	30%	0.302	C	S	.	.	H	α-helix	trans	-67.9	-35.4	177.7	-78.6	-63.5	0	0	0	112.8	T146 L232 T234 F238 I239 C240 V290 T293 F294 V297	T146-Y236 HydrophobicContact CG2-CD2 4.04Å; T146-Y236 HydrophobicContact CG2-CE1 4.34Å; T146-Y236 HydrophobicContact CG2-CE2 3.53Å; T146-Y236 PolarHBondContact OG1-OH 3.35Å; L232-Y236 VanDerWaalsContact O-CD2 3.23Å; L232-Y236 WeakPolarHBondContact O-CD2 3.45Å; L232-Y236 PolarHBondContact O-N 3.21Å; T234-Y236 PolarHBondContact O-N 3.44Å; Y236-F238 VanDerWaalsContact C-N 3.33Å; Y236-F238 PolarHBondContact O-N 3.47Å; Y236-I239 HydrophobicContact CD1-CD1 4.01Å; Y236-I239 HydrophobicContact CE1-CD1 4.23Å; Y236-I239 PolarHBondContact O-N 2.92Å; Y236-C240 VanDerWaalsContact O-CB 3.3Å; Y236-C240 WeakPolarHBondContact O-CB 3.28Å; Y236-C240 PolarHBondContact O-N 3Å; Y236-C240 PolarHBondContact O-SG 3.26Å; Y236-V290 HydrophobicContact CE1-CG1 4.39Å; Y236-T293 WeakPolarHBondContact OH-CB 3.1Å; Y236-T293 PolarHBondContact OH-O 3.37Å; Y236-T293 PolarHBondContact OH-OG1 2.97Å; Y236-F294 HydrophobicContact CD1-CB 4.49Å; Y236-F294 AromaticContact CD1-CD2 3.97Å; Y236-F294 HydrophobicContact CD1-CD2 3.97Å; Y236-F294 HydrophobicContact CD2-CD2 4.37Å; Y236-F294 HydrophobicContact CE1-CB 3.89Å; Y236-F294 HydrophobicContact CE1-CD2 4.15Å; Y236-F294 HydrophobicContact CG-CD2 4.11Å; Y236-F294 WeakPolarHBondContact OH-CA 3.42Å; Y236-F294 PolarHBondContact OH-N 2.66Å; Y236-F294 VanDerWaalsContact OH-N 3.08Å; Y236-V297 HydrophobicContact CD2-CG1 4.3Å; Y236-V297 HydrophobicContact CE2-CB 3.85Å; Y236-V297 HydrophobicContact CE2-CG1 3.84Å; Y236-V297 HydrophobicContact CE2-CG2 3.83Å
237	G	93.5	Very high	92.5	Very high	42 Å²	42	54.2 Å²	54.2	43%	0.433	31%	0.307	S	S	.	.	H	α-helix	trans	-54	-50.2	171.8	0	0	0	0	0	111.5	G233 T234 C240 Y241	G233-G237 PolarHBondContact O-N 3.06Å; T234-G237 PolarHBondContact O-N 2.97Å; G237-C240 PolarHBondContact O-N 3.45Å; G237-Y241 WeakPolarHBondContact O-CB 3.4Å; G237-Y241 PolarHBondContact O-N 2.89Å
238	F	94.3	Very high	91.9	Very high	116 Å²	116	60.1 Å²	60.1	51%	0.509	32%	0.321	S	S	.	.	H	α-helix	trans	-67.3	-38.8	176.3	-71	-65.5	0	0	0	113.7	Y150 T234 C235 Y236 Y241 N242	Y150-F238 HydrophobicContact CD2-CB 3.85Å; Y150-F238 HydrophobicContact CE2-CB 3.47Å; Y150-F238 VanDerWaalsContact CE2-CB 3.47Å; Y150-F238 HydrophobicContact CE2-CD2 4.1Å; Y150-F238 AromaticContact CE2-CG 3.93Å; Y150-F238 HydrophobicContact CE2-CG 3.93Å; T234-F238 WeakPolarHBondContact O-CD2 3.46Å; T234-F238 PolarHBondContact O-N 3.17Å; C235-F238 PolarHBondContact O-N 2.7Å; Y236-F238 VanDerWaalsContact C-N 3.33Å; Y236-F238 PolarHBondContact O-N 3.47Å; F238-Y241 PolarHBondContact O-N 2.98Å; F238-N242 VanDerWaalsContact O-CB 3.31Å; F238-N242 WeakPolarHBondContact O-CB 3.31Å; F238-N242 PolarHBondContact O-N 2.95Å
239	I	92.2	Very high	91.1	Very high	0 Å²	0	62 Å²	62	0%	0	34%	0.341	C	S	.	.	H	α-helix	trans	-61	-48.8	176.6	-70.6	164.4	0	0	0	110.1	R149 Y150 V153 C235 Y236 N242 I243 V290	R149-I239 HydrophobicContact CB-CD1 4.23Å; Y150-I239 HydrophobicContact CD2-CG1 4.32Å; V153-I239 HydrophobicContact CG1-CG2 4.45Å; C235-I239 WeakPolarHBondContact O-CD1 3.25Å; C235-I239 WeakPolarHBondContact O-CG1 3.25Å; C235-I239 PolarHBondContact O-N 3.39Å; Y236-I239 HydrophobicContact CD1-CD1 4.01Å; Y236-I239 HydrophobicContact CE1-CD1 4.23Å; Y236-I239 PolarHBondContact O-N 2.92Å; I239-N242 PolarHBondContact O-N 2.98Å; I239-I243 HydrophobicContact CG2-CD1 3.67Å; I239-I243 HydrophobicContact CG2-CG1 4.44Å; I239-I243 WeakPolarHBondContact O-CB 3.49Å; I239-I243 VanDerWaalsContact O-CG1 3.24Å; I239-I243 WeakPolarHBondContact O-CG1 3.34Å; I239-I243 PolarHBondContact O-N 3.45Å; I239-V290 HydrophobicContact CG2-CG1 3.65Å; I239-V290 HydrophobicContact CG2-CG2 4.39Å
240	C	91.4	Very high	90	Very high	72 Å²	72	65 Å²	65	49%	0.486	35%	0.351	S	S	.	.	H	α-helix	trans	-61.9	-45	178.5	-71.9	0	0	0	0	111.3	Y236 G237 N242 I243 W244	Y236-C240 VanDerWaalsContact O-CB 3.3Å; Y236-C240 WeakPolarHBondContact O-CB 3.28Å; Y236-C240 PolarHBondContact O-N 3Å; Y236-C240 PolarHBondContact O-SG 3.26Å; G237-C240 PolarHBondContact O-N 3.45Å; C240-N242 PolarHBondContact O-N 3.49Å; C240-I243 PolarHBondContact O-N 2.93Å; C240-W244 WeakPolarHBondContact O-CB 3.28Å; C240-W244 PolarHBondContact O-N 3.05Å
241	Y	91.3	Very high	88.9	Confident	149 Å²	149	64.8 Å²	64.8	58%	0.584	35%	0.35	S	S	*	.	H	α-helix	trans	-58.6	-48	174.9	178.4	-99	0	0	0	111.9	G237 F238 I243 W244 C245	G237-Y241 WeakPolarHBondContact O-CB 3.4Å; G237-Y241 PolarHBondContact O-N 2.89Å; F238-Y241 PolarHBondContact O-N 2.98Å; Y241-I243 PolarHBondContact O-N 2.87Å; Y241-W244 PolarHBondContact O-N 2.94Å; Y241-C245 PolarHBondContact O-N 3.3Å; Y241-C245 PolarHBondContact O-SG 2.98Å; Y241-C245 VanDerWaalsContact O-SG 3.34Å
242	N	89	Confident	87.9	Confident	40 Å²	40	64.2 Å²	64.2	21%	0.214	36%	0.356	C	S	.	.	H	α-helix	trans	-63.6	-41.2	179.6	-168.6	-72.5	0	0	0	112.1	V153 F238 I239 C240 N246	V153-N242 HydrophobicContact CG1-CB 4.49Å; F238-N242 VanDerWaalsContact O-CB 3.31Å; F238-N242 WeakPolarHBondContact O-CB 3.31Å; F238-N242 PolarHBondContact O-N 2.95Å; I239-N242 PolarHBondContact O-N 2.98Å; C240-N242 PolarHBondContact O-N 3.49Å; N242-N246 WeakPolarHBondContact O-CB 3.49Å; N242-N246 PolarHBondContact O-N 2.94Å; N242-N246 PolarHBondContact O-ND2 2.95Å; N242-N246 PolarHBondContact OD1-ND2 3.31Å
243	I	87.5	Confident	86.5	Confident	42 Å²	42	67 Å²	67	22%	0.215	38%	0.375	C	S	.	.	H	α-helix	trans	-62.1	-46.6	174.5	-69.2	167.5	0	0	0	110.1	V153 I239 C240 Y241 N246 V247 I282	V153-I243 HydrophobicContact CG1-CG1 4.36Å; I239-I243 HydrophobicContact CG2-CD1 3.67Å; I239-I243 HydrophobicContact CG2-CG1 4.44Å; I239-I243 WeakPolarHBondContact O-CB 3.49Å; I239-I243 VanDerWaalsContact O-CG1 3.24Å; I239-I243 WeakPolarHBondContact O-CG1 3.34Å; I239-I243 PolarHBondContact O-N 3.45Å; C240-I243 PolarHBondContact O-N 2.93Å; Y241-I243 PolarHBondContact O-N 2.87Å; I243-N246 PolarHBondContact O-N 3.09Å; I243-V247 HydrophobicContact CG2-CG2 4.41Å; I243-V247 WeakPolarHBondContact O-CG2 3.35Å; I243-V247 PolarHBondContact O-N 3.5Å; I243-I282 HydrophobicContact CB-CD1 4.48Å; I243-I282 HydrophobicContact CG1-CD1 3.75Å
244	W	88.1	Confident	85	Confident	140 Å²	140	74.6 Å²	74.6	53%	0.53	39%	0.389	S	S	.	.	H	α-helix	trans	-61.9	-47.1	179.6	179.4	80.8	0	0	0	112.3	C240 Y241 N246 V247 R248	C240-W244 WeakPolarHBondContact O-CB 3.28Å; C240-W244 PolarHBondContact O-N 3.05Å; Y241-W244 PolarHBondContact O-N 2.94Å; W244-N246 VanDerWaalsContact C-N 3.31Å; W244-N246 PolarHBondContact O-N 3.19Å; W244-V247 PolarHBondContact O-N 3.47Å; W244-R248 WeakPolarHBondContact O-CB 3.35Å; W244-R248 PolarHBondContact O-N 3.39Å
245	C	87.1	Confident	83.3	Confident	45 Å²	45	78.3 Å²	78.3	30%	0.304	40%	0.402	S	S	.	.	H	α-helix	trans	-58.9	-40.6	175	-69.7	0	0	0	0	112.3	Y241 G249	Y241-C245 PolarHBondContact O-N 3.3Å; Y241-C245 PolarHBondContact O-SG 2.98Å; Y241-C245 VanDerWaalsContact O-SG 3.34Å; C245-G249 PolarHBondContact O-N 2.75Å
246	N	82.9	Confident	81.6	Confident	27 Å²	27	81.2 Å²	81.2	14%	0.144	42%	0.422	C	S	.	.	H	α-helix	trans	-69.3	-35.3	177.5	-77.5	-40.1	0	0	0	112.9	N242 I243 W244 K250 I282	N242-N246 WeakPolarHBondContact O-CB 3.49Å; N242-N246 PolarHBondContact O-N 2.94Å; N242-N246 PolarHBondContact O-ND2 2.95Å; N242-N246 PolarHBondContact OD1-ND2 3.31Å; I243-N246 PolarHBondContact O-N 3.09Å; W244-N246 VanDerWaalsContact C-N 3.31Å; W244-N246 PolarHBondContact O-N 3.19Å; N246-K250 VanDerWaalsContact O-CG 3.3Å; N246-K250 WeakPolarHBondContact O-CG 3.38Å; N246-K250 PolarHBondContact O-N 3.44Å; N246-I282 HydrophobicContact CB-CD1 4.47Å
247	V	82.4	Confident	79.9	Confident	84 Å²	84	86.4 Å²	86.4	51%	0.509	45%	0.445	S	S	.	.	H	α-helix	trans	-69.1	-47.9	174.5	172.3	0	0	0	0	110.2	I243 W244 G249 K250 T251	I243-V247 HydrophobicContact CG2-CG2 4.41Å; I243-V247 WeakPolarHBondContact O-CG2 3.35Å; I243-V247 PolarHBondContact O-N 3.5Å; W244-V247 PolarHBondContact O-N 3.47Å; V247-G249 PolarHBondContact O-N 2.89Å; V247-K250 WeakPolarHBondContact O-CB 3.33Å; V247-K250 PolarHBondContact O-N 2.85Å; V247-K250 VanDerWaalsContact O-N 3.14Å; V247-T251 PolarHBondContact O-N 3.3Å; V247-T251 PolarHBondContact O-OG1 2.88Å
248	R	84	Confident	78.1	Confident	161 Å²	161	86.6 Å²	86.6	61%	0.608	45%	0.447	S	S	*	.	H	α-helix	trans	-60.5	-43.2	178.8	-172.8	174.4	177	175.3	-1.5	112.3	W244 K250 T251 A252	W244-R248 WeakPolarHBondContact O-CB 3.35Å; W244-R248 PolarHBondContact O-N 3.39Å; R248-K250 VanDerWaalsContact C-N 3.3Å; R248-K250 PolarHBondContact O-N 3.18Å; R248-T251 PolarHBondContact O-N 3.43Å; R248-A252 PolarHBondContact O-N 2.87Å
249	G	80	Confident	76.3	Confident	42 Å²	42	84.6 Å²	84.6	43%	0.433	45%	0.452	S	S	.	.	H	α-helix	trans	-62.8	-33.7	175.8	0	0	0	0	0	113.6	C245 V247 S253	C245-G249 PolarHBondContact O-N 2.75Å; V247-G249 PolarHBondContact O-N 2.89Å; G249-S253 WeakPolarHBondContact O-CB 3.47Å; G249-S253 PolarHBondContact O-N 3.2Å
250	K	74.4	Confident	74.4	Confident	99 Å²	99	90.5 Å²	90.5	43%	0.43	48%	0.48	S	S	.	.	H	α-helix	trans	-71.6	-39.3	174.8	-75.9	174.5	179.7	-179.7	0	112.6	N246 V247 R248 R254	N246-K250 VanDerWaalsContact O-CG 3.3Å; N246-K250 WeakPolarHBondContact O-CG 3.38Å; N246-K250 PolarHBondContact O-N 3.44Å; V247-K250 WeakPolarHBondContact O-CB 3.33Å; V247-K250 PolarHBondContact O-N 2.85Å; V247-K250 VanDerWaalsContact O-N 3.14Å; R248-K250 VanDerWaalsContact C-N 3.3Å; R248-K250 PolarHBondContact O-N 3.18Å; K250-R254 WeakPolarHBondContact O-CB 3.37Å; K250-R254 WeakPolarHBondContact O-CG 3.18Å; K250-R254 PolarHBondContact O-N 3.46Å
251	T	75.4	Confident	72.5	Confident	85 Å²	85	94.5 Å²	94.5	52%	0.521	49%	0.491	S	S	.	.	H	α-helix	trans	-65.3	-44.4	176.4	-53	0	0	0	0	110.9	V247 R248 R254 Q255	V247-T251 PolarHBondContact O-N 3.3Å; V247-T251 PolarHBondContact O-OG1 2.88Å; R248-T251 PolarHBondContact O-N 3.43Å; T251-R254 PolarHBondContact O-N 3.36Å; T251-Q255 PolarHBondContact O-N 3.31Å
252	A	75.3	Confident	70.6	Confident	57 Å²	57	91.7 Å²	91.7	47%	0.471	50%	0.499	S	S	.	.	H	α-helix	trans	-63	-43.9	176.6	0	0	0	0	0	112.7	R248 R254 Q255 S256	R248-A252 PolarHBondContact O-N 2.87Å; A252-R254 VanDerWaalsContact C-N 3.35Å; A252-R254 PolarHBondContact O-N 3.06Å; A252-Q255 PolarHBondContact O-N 2.96Å; A252-S256 PolarHBondContact O-N 3.15Å
253	S	66.5	Low	68.6	Low	59 Å²	59	92.8 Å²	92.8	41%	0.413	52%	0.519	S	S	.	.	H	α-helix	trans	-66.3	-34.4	177.6	-178.2	0	0	0	0	112.9	G249 K257	G249-S253 WeakPolarHBondContact O-CB 3.47Å; G249-S253 PolarHBondContact O-N 3.2Å; S253-K257 WeakPolarHBondContact O-CG 3.37Å; S253-K257 PolarHBondContact O-N 2.87Å; S253-K257 VanDerWaalsContact O-N 3.13Å
254	R	64.3	Low	66.9	Low	207 Å²	207	95.1 Å²	95.1	78%	0.781	54%	0.535	S	S	*	.	H	α-helix	trans	-67.1	-39.9	173.8	-83.6	-177.8	161.9	-172.3	-7.6	112.3	K250 T251 A252 K257 G258	K250-R254 WeakPolarHBondContact O-CB 3.37Å; K250-R254 WeakPolarHBondContact O-CG 3.18Å; K250-R254 PolarHBondContact O-N 3.46Å; T251-R254 PolarHBondContact O-N 3.36Å; A252-R254 VanDerWaalsContact C-N 3.35Å; A252-R254 PolarHBondContact O-N 3.06Å; R254-K257 PolarHBondContact O-N 3.34Å; R254-G258 PolarHBondContact O-N 2.72Å
255	Q	61	Low	64.9	Low	150 Å²	150	93.3 Å²	93.3	70%	0.701	55%	0.55	S	S	*	*	H	α-helix	trans	-67.4	-40.6	178.4	-164.6	171.3	3.4	0	0	111.7	T251 A252 G258 A259	T251-Q255 PolarHBondContact O-N 3.31Å; A252-Q255 PolarHBondContact O-N 2.96Å; Q255-G258 PolarHBondContact O-N 3.07Å; Q255-A259 PolarHBondContact O-N 3.34Å
256	S	59.5	Low	62.8	Low	75 Å²	75	100.4 Å²	100.4	52%	0.524	58%	0.576	S	S	.	*	H	α-helix	trans	-62.1	-44	174.5	-165.8	0	0	0	0	112.2	A252 A259 E260	A252-S256 PolarHBondContact O-N 3.15Å; S256-A259 PolarHBondContact O-N 2.95Å; S256-E260 WeakPolarHBondContact O-CB 3.42Å; S256-E260 PolarHBondContact O-N 3.04Å; S256-E260 VanDerWaalsContact O-N 3.14Å
257	K	58.9	Low	60.9	Low	122 Å²	122	107.3 Å²	107.3	53%	0.53	61%	0.608	S	S	.	*	H	α-helix	trans	-70	-32.4	179.1	-72.3	-175.4	177.4	-170.2	0	113.6	S253 R254 Q261	S253-K257 WeakPolarHBondContact O-CG 3.37Å; S253-K257 PolarHBondContact O-N 2.87Å; S253-K257 VanDerWaalsContact O-N 3.13Å; R254-K257 PolarHBondContact O-N 3.34Å; K257-Q261 WeakPolarHBondContact O-CB 3.44Å; K257-Q261 WeakPolarHBondContact O-CG 3.28Å; K257-Q261 PolarHBondContact O-N 3.15Å
258	G	55.4	Low	58.8	Low	46 Å²	46	113.4 Å²	113.4	47%	0.474	63%	0.627	S	S	.	*	H	α-helix	trans	-69.4	-34	176.3	0	0	0	0	0	113.3	R254 Q255	R254-G258 PolarHBondContact O-N 2.72Å; Q255-G258 PolarHBondContact O-N 3.07Å
259	A	56.4	Low	56.5	Low	74 Å²	74	109.3 Å²	109.3	61%	0.612	64%	0.635	S	S	*	*	H	α-helix	trans	-74.4	-38.7	174.6	0	0	0	0	0	112.2	Q255 S256 A262	Q255-A259 PolarHBondContact O-N 3.34Å; S256-A259 PolarHBondContact O-N 2.95Å; A259-A262 PolarHBondContact O-N 3.49Å
260	E	52.5	Low	54.4	Low	125 Å²	125	116.1 Å²	116.1	58%	0.584	65%	0.653	S	S	*	*	H	α-helix	trans	-73	-32.7	-179.7	-143.9	171.6	-175.7	0	0	112.3	S256 A262 G263 V264	S256-E260 WeakPolarHBondContact O-CB 3.42Å; S256-E260 PolarHBondContact O-N 3.04Å; S256-E260 VanDerWaalsContact O-N 3.14Å; E260-A262 VanDerWaalsContact C-N 3.29Å; E260-A262 PolarHBondContact O-N 3.39Å; E260-G263 PolarHBondContact O-N 3.22Å; E260-V264 HydrophobicContact CG-CG2 4.23Å; E260-V264 WeakPolarHBondContact O-CB 3.46Å; E260-V264 VanDerWaalsContact O-CG2 3.22Å; E260-V264 WeakPolarHBondContact O-CG2 3.45Å; E260-V264 PolarHBondContact O-N 3.47Å
261	Q	50.7	Low	52.5	Low	156 Å²	156	118 Å²	118	73%	0.729	67%	0.667	S	S	*	*	H	α-helix	trans	-69.5	-21.2	174.5	-81.7	177.3	-34.4	0	0	114.1	K257	K257-Q261 WeakPolarHBondContact O-CB 3.44Å; K257-Q261 WeakPolarHBondContact O-CG 3.28Å; K257-Q261 PolarHBondContact O-N 3.15Å
262	A	50.8	Low	50.8	Low	90 Å²	90	122.3 Å²	122.3	74%	0.744	69%	0.686	S	S	*	*	H	α-helix	trans	-78.3	-22.4	173.5	0	0	0	0	0	113	A259 E260	A259-A262 PolarHBondContact O-N 3.49Å; E260-A262 VanDerWaalsContact C-N 3.29Å; E260-A262 PolarHBondContact O-N 3.39Å
263	G	47.8	Very low	49.1	Very low	63 Å²	63	123.1 Å²	123.1	65%	0.649	69%	0.693	S	S	*	*	H	α-helix	trans	-102	-15.1	-178.1	0	0	0	0	0	115.9	E260	E260-G263 PolarHBondContact O-N 3.22Å
264	V	51.8	Low	47.7	Very low	91 Å²	91	126.6 Å²	126.6	55%	0.552	71%	0.714	S	S	*	*			trans	-116.1	18.3	-165.5	-170.8	0	0	0	0	113.6	E260 F266	E260-V264 HydrophobicContact CG-CG2 4.23Å; E260-V264 WeakPolarHBondContact O-CB 3.46Å; E260-V264 VanDerWaalsContact O-CG2 3.22Å; E260-V264 WeakPolarHBondContact O-CG2 3.45Å; E260-V264 PolarHBondContact O-N 3.47Å; V264-F266 PolarHBondContact O-N 3.29Å
265	A	45.7	Very low	46.5	Very low	102 Å²	102	121.8 Å²	121.8	84%	0.843	71%	0.711	S	S	*	*	T	Hydrogen-bonded Turn	trans	-67.2	2.4	170.4	0	0	0	0	0	114.2
266	F	43.5	Very low	45.5	Very low	193 Å²	193	120.8 Å²	120.8	85%	0.846	72%	0.715	S	S	*	*	T	Hydrogen-bonded Turn	trans	-114.1	0.8	-171.9	-161.8	-105	0	0	0	116.6	V264	V264-F266 PolarHBondContact O-N 3.29Å
267	Q	43.4	Very low	44.6	Very low	173 Å²	173	121.9 Å²	121.9	81%	0.808	72%	0.722	S	S	*	*			trans	-132.1	93.5	178.1	-115.9	171.4	-9.9	0	0	113.8	G269	Q267-G269 PolarHBondContact O-N 2.87Å
268	K	37.1	Very low	43.9	Very low	212 Å²	212	121 Å²	121	92%	0.922	73%	0.731	S	S	*	*			trans	-54.8	126.8	158.6	-92	175.1	170.7	173.9	0	110
269	G	36.5	Very low	43.7	Very low	74 Å²	74	123.2 Å²	123.2	76%	0.763	74%	0.736	S	S	*	*			trans	86	80.1	139.2	0	0	0	0	0	117.2	Q267	Q267-G269 PolarHBondContact O-N 2.87Å
270	F	36.1	Very low	43.7	Very low	186 Å²	186	127 Å²	127	82%	0.816	74%	0.738	S	S	*	*			trans	-163.8	115	139.9	-154	-115.8	0	0	0	111.4
271	L	34.8	Very low	44.3	Very low	139 Å²	139	124.9 Å²	124.9	73%	0.728	74%	0.737	S	S	*	*			trans	26.9	95.2	150.1	-54.6	180	0	0	0	118.9
272	L	39.7	Very low	45.4	Very low	175 Å²	175	119 Å²	119	92%	0.916	71%	0.71	S	S	*	*			trans	-141.2	121.5	151.9	-82.7	178.2	0	0	0	110.7
273	A	38.3	Very low	46.7	Very low	74 Å²	74	117.7 Å²	117.7	61%	0.612	70%	0.696	S	S	*	*			trans	-51.8	146.7	-179.4	0	0	0	0	0	112.6	C275	A273-C275 PolarHBondContact O-N 3.35Å
274	P	37.6	Very low	48.3	Very low	131 Å²	131	125.7 Å²	125.7	85%	0.851	71%	0.707	S	S	*	*			trans	-72.3	84.2	169.3	30.2	-30.2	0	0	0	108.4	V276	P274-V276 PolarHBondContact O-N 2.89Å
275	C	39.2	Very low	49.6	Very low	107 Å²	107	124.3 Å²	124.3	72%	0.723	71%	0.705	S	S	*	*			trans	-57	125.5	177.5	-70.2	0	0	0	0	110.6	A273 S277	A273-C275 PolarHBondContact O-N 3.35Å; C275-S277 PolarHBondContact O-N 3.14Å
276	V	40.2	Very low	51.3	Low	129 Å²	129	123 Å²	123	78%	0.782	68%	0.68	S	S	*	*			trans	-51.1	93.6	-178.8	-178.1	0	0	0	0	111.6	P274 V279	P274-V276 PolarHBondContact O-N 2.89Å; V276-V279 HydrophobicContact CG1-CG2 4.04Å
277	S	40.3	Very low	53.2	Low	98 Å²	98	116.5 Å²	116.5	69%	0.685	65%	0.654	S	S	*	*			trans	-114.9	4.2	170.8	52.8	0	0	0	0	113.5	C275 V279	C275-S277 PolarHBondContact O-N 3.14Å; S277-V279 PolarHBondContact O-N 2.88Å
278	S	44.7	Very low	55.2	Low	103 Å²	103	114.3 Å²	114.3	72%	0.72	64%	0.638	S	S	*	*	G	3₁₀ helix	trans	-71.6	-10.2	-175	-163.8	0	0	0	0	114.8	K280	S278-K280 PolarHBondContact O-N 3.21Å
279	V	50.5	Low	57.5	Low	93 Å²	93	105.6 Å²	105.6	56%	0.564	60%	0.602	S	S	*	*	G	3₁₀ helix	trans	-81.8	-5.6	-169.3	-164.4	0	0	0	0	114.2	V276 S277	V276-V279 HydrophobicContact CG1-CG2 4.04Å; S277-V279 PolarHBondContact O-N 2.88Å
280	K	55.7	Low	60	Low	152 Å²	152	102.6 Å²	102.6	66%	0.661	57%	0.57	S	S	*	*	G	3₁₀ helix	trans	-104.9	12.1	-178	-70.3	-175.5	-179.4	177.5	0	115.6	S278 I282	S278-K280 PolarHBondContact O-N 3.21Å; K280-I282 PolarHBondContact O-N 3.48Å
281	S	65.4	Low	62.6	Low	82 Å²	82	99.8 Å²	99.8	57%	0.573	56%	0.557	S	S	*	*			trans	-85.8	104.2	174.2	72.4	0	0	0	0	111.7	S283	S281-S283 PolarHBondContact O-N 3.44Å
282	I	74.4	Confident	65.2	Low	31 Å²	31	93.4 Å²	93.4	16%	0.159	52%	0.523	C	S	.	.			trans	-66.5	117	167.9	-55.4	175.5	0	0	0	108	V153 I243 N246 K280 K286 I287	V153-I282 HydrophobicContact CG1-CD1 4.04Å; I243-I282 HydrophobicContact CB-CD1 4.48Å; I243-I282 HydrophobicContact CG1-CD1 3.75Å; N246-I282 HydrophobicContact CB-CD1 4.47Å; K280-I282 PolarHBondContact O-N 3.48Å; I282-K286 HydrophobicContact CG2-CB 3.92Å; I282-K286 HydrophobicContact CG2-CD 4.39Å; I282-I287 HydrophobicContact CB-CG1 4.49Å; I282-I287 HydrophobicContact CG2-CD1 4.23Å; I282-I287 HydrophobicContact CG2-CG1 3.67Å
283	S	78.9	Confident	67.5	Low	64 Å²	64	85 Å²	85	45%	0.448	48%	0.48	S	S	.	.			trans	-59.8	143.2	177.5	169.7	0	0	0	0	111.8	S281 A285 K286 I287	S281-S283 PolarHBondContact O-N 3.44Å; S283-A285 PolarHBondContact O-N 3.08Å; S283-A285 VanDerWaalsContact O-N 3.16Å; S283-A285 PolarHBondContact OG-N 2.8Å; S283-K286 WeakPolarHBondContact O-CB 3.48Å; S283-K286 PolarHBondContact O-N 3.25Å; S283-I287 PolarHBondContact O-N 3.47Å
284	R	80.8	Confident	70.1	Confident	230 Å²	230	86.3 Å²	86.3	87%	0.868	47%	0.471	S	S	*	.	H	α-helix	trans	-52.7	-36	174	-67.4	-175	178.2	-158.1	0	112.1	K286 I287 R288	R284-K286 PolarHBondContact O-N 3.45Å; R284-I287 PolarHBondContact O-N 3.31Å; R284-R288 PolarHBondContact O-N 3.03Å
285	A	78.2	Confident	72.8	Confident	62 Å²	62	82.7 Å²	82.7	51%	0.512	45%	0.447	S	S	.	.	H	α-helix	trans	-63.6	-39.5	176.7	0	0	0	0	0	112.3	S283 R288 T289	S283-A285 PolarHBondContact O-N 3.08Å; S283-A285 VanDerWaalsContact O-N 3.16Å; S283-A285 PolarHBondContact OG-N 2.8Å; A285-R288 PolarHBondContact O-N 3.28Å; A285-T289 WeakPolarHBondContact O-CG2 3.25Å; A285-T289 PolarHBondContact O-N 2.97Å; A285-T289 VanDerWaalsContact O-N 3.17Å
286	K	81.7	Confident	75.3	Confident	75 Å²	75	77.6 Å²	77.6	33%	0.326	41%	0.413	S	S	.	.	H	α-helix	trans	-65	-46.2	175.7	-69.5	-172.9	177.6	-172.5	0	111	A152 I282 S283 R284 R288 T289 V290	A152-K286 PolarHBondContact O-NZ 3.37Å; I282-K286 HydrophobicContact CG2-CB 3.92Å; I282-K286 HydrophobicContact CG2-CD 4.39Å; S283-K286 WeakPolarHBondContact O-CB 3.48Å; S283-K286 PolarHBondContact O-N 3.25Å; R284-K286 PolarHBondContact O-N 3.45Å; K286-R288 VanDerWaalsContact C-N 3.3Å; K286-R288 PolarHBondContact O-N 3.24Å; K286-T289 PolarHBondContact O-N 3.23Å; K286-T289 VanDerWaalsContact O-N 3.14Å; K286-T289 PolarHBondContact O-OG1 3.39Å; K286-V290 WeakPolarHBondContact O-CG2 3.39Å; K286-V290 PolarHBondContact O-N 3.27Å
287	I	83.8	Confident	77.7	Confident	57 Å²	57	71.7 Å²	71.7	29%	0.292	38%	0.377	S	S	.	.	H	α-helix	trans	-60.3	-42.5	178.4	-62	175.5	0	0	0	110.6	I282 S283 R284 T289 V290 K291	I282-I287 HydrophobicContact CB-CG1 4.49Å; I282-I287 HydrophobicContact CG2-CD1 4.23Å; I282-I287 HydrophobicContact CG2-CG1 3.67Å; S283-I287 PolarHBondContact O-N 3.47Å; R284-I287 PolarHBondContact O-N 3.31Å; I287-T289 VanDerWaalsContact C-N 3.3Å; I287-T289 PolarHBondContact O-N 3.37Å; I287-V290 PolarHBondContact O-N 3.37Å; I287-K291 HydrophobicContact CG2-CD 4.35Å; I287-K291 HydrophobicContact CG2-CG 4.36Å; I287-K291 WeakPolarHBondContact O-CG 3.34Å; I287-K291 PolarHBondContact O-N 3.08Å
288	R	85.9	Confident	80.2	Confident	126 Å²	126	69.9 Å²	69.9	48%	0.475	36%	0.362	S	S	.	.	H	α-helix	trans	-56.3	-45.4	175.6	-173.8	177.2	-177.7	168.5	5.7	111.7	R284 A285 K286 K291 M292 F351	R284-R288 PolarHBondContact O-N 3.03Å; A285-R288 PolarHBondContact O-N 3.28Å; K286-R288 VanDerWaalsContact C-N 3.3Å; K286-R288 PolarHBondContact O-N 3.24Å; R288-K291 PolarHBondContact O-N 3.25Å; R288-M292 PolarHBondContact O-N 3.22Å; R288-F351 PolarHBondContact NE-O 2.81Å; R288-F351 PolarHBondContact NH2-O 3.39Å
289	T	85.3	Confident	82.6	Confident	29 Å²	29	65.9 Å²	65.9	18%	0.178	34%	0.335	C	S	.	.	H	α-helix	trans	-67.1	-36.8	177.7	61.3	0	0	0	0	113.5	M86 R149 A285 K286 I287 M292 T293	M86-T289 VanDerWaalsContact CE-CB 3.44Å; M86-T289 HydrophobicContact CE-CG2 3.63Å; R149-T289 PolarHBondContact NH1-OG1 3.44Å; A285-T289 WeakPolarHBondContact O-CG2 3.25Å; A285-T289 PolarHBondContact O-N 2.97Å; A285-T289 VanDerWaalsContact O-N 3.17Å; K286-T289 PolarHBondContact O-N 3.23Å; K286-T289 VanDerWaalsContact O-N 3.14Å; K286-T289 PolarHBondContact O-OG1 3.39Å; I287-T289 VanDerWaalsContact C-N 3.3Å; I287-T289 PolarHBondContact O-N 3.37Å; T289-M292 WeakPolarHBondContact O-CB 3.34Å; T289-M292 PolarHBondContact O-N 3.46Å; T289-T293 WeakPolarHBondContact O-CG2 3.35Å; T289-T293 PolarHBondContact O-N 3.35Å; T289-T293 PolarHBondContact O-OG1 2.86Å
290	V	88.5	Confident	84.6	Confident	12 Å²	12	61.6 Å²	61.6	7%	0.073	31%	0.309	C	S	.	.	H	α-helix	trans	-65.8	-43	175.8	170.8	0	0	0	0	110.8	R149 V153 Y236 I239 K286 I287 M292 T293 F294	R149-V290 HydrophobicContact CB-CG2 4.43Å; V153-V290 HydrophobicContact CG2-CG2 3.81Å; Y236-V290 HydrophobicContact CE1-CG1 4.39Å; I239-V290 HydrophobicContact CG2-CG1 3.65Å; I239-V290 HydrophobicContact CG2-CG2 4.39Å; K286-V290 WeakPolarHBondContact O-CG2 3.39Å; K286-V290 PolarHBondContact O-N 3.27Å; I287-V290 PolarHBondContact O-N 3.37Å; V290-M292 VanDerWaalsContact C-N 3.34Å; V290-M292 PolarHBondContact O-N 3.33Å; V290-T293 PolarHBondContact O-N 2.91Å; V290-T293 PolarHBondContact O-OG1 2.98Å; V290-T293 VanDerWaalsContact O-OG1 3.05Å; V290-F294 VanDerWaalsContact O-CB 3.3Å; V290-F294 WeakPolarHBondContact O-CB 3.34Å; V290-F294 PolarHBondContact O-N 3.25Å
291	K	89.7	Confident	86.5	Confident	127 Å²	127	57 Å²	57	55%	0.552	29%	0.291	S	S	*	.	H	α-helix	trans	-61.2	-44.1	175.5	-72.1	-174.7	175.3	-168.6	0	111.3	I287 R288 F294 V295 F351	I287-K291 HydrophobicContact CG2-CD 4.35Å; I287-K291 HydrophobicContact CG2-CG 4.36Å; I287-K291 WeakPolarHBondContact O-CG 3.34Å; I287-K291 PolarHBondContact O-N 3.08Å; R288-K291 PolarHBondContact O-N 3.25Å; K291-F294 PolarHBondContact O-N 2.92Å; K291-V295 WeakPolarHBondContact O-CG2 3.23Å; K291-V295 PolarHBondContact O-N 3.3Å; K291-F351 HydrophobicContact CB-CE1 3.7Å; K291-F351 HydrophobicContact CB-CZ 4.39Å
292	M	89.5	Confident	87.9	Confident	4 Å²	4	57.5 Å²	57.5	2%	0.02	29%	0.29	C	S	.	.	H	α-helix	trans	-57.6	-53.5	175.9	-175.8	-175.2	86.3	0	0	111.3	M86 I90 R288 T289 V290 F294 V295 I296 I347 Y348 F351	M86-M292 HydrophobicContact CE-CE 3.9Å; M86-M292 HydrophobicContact CG-CE 4.39Å; M86-M292 HydrophobicContact SD-CE 3.91Å; I90-M292 HydrophobicContact CD1-CE 4.22Å; I90-M292 HydrophobicContact CG1-CE 4.47Å; R288-M292 PolarHBondContact O-N 3.22Å; T289-M292 WeakPolarHBondContact O-CB 3.34Å; T289-M292 PolarHBondContact O-N 3.46Å; V290-M292 VanDerWaalsContact C-N 3.34Å; V290-M292 PolarHBondContact O-N 3.33Å; M292-F294 VanDerWaalsContact C-N 3.25Å; M292-F294 PolarHBondContact O-N 3.46Å; M292-V295 PolarHBondContact O-N 3.48Å; M292-I296 HydrophobicContact CG-CD1 4.34Å; M292-I296 WeakPolarHBondContact O-CG1 3.36Å; M292-I296 PolarHBondContact O-N 3.43Å; M292-I296 VanDerWaalsContact O-N 3.15Å; M292-I347 HydrophobicContact CG-CG2 4.04Å; M292-Y348 HydrophobicContact CE-CD1 4.08Å; M292-Y348 HydrophobicContact CE-CE1 4.01Å; M292-Y348 HydrophobicContact SD-CD1 3.87Å; M292-Y348 HydrophobicContact SD-CE1 4.36Å; M292-F351 HydrophobicContact CB-CB 3.68Å; M292-F351 HydrophobicContact CB-CD1 3.71Å; M292-F351 HydrophobicContact CB-CD2 4.22Å; M292-F351 HydrophobicContact CB-CE1 4.41Å; M292-F351 HydrophobicContact CB-CG 3.59Å; M292-F351 HydrophobicContact CG-CB 3.49Å; M292-F351 VanDerWaalsContact CG-CB 3.49Å; M292-F351 HydrophobicContact CG-CD1 4.39Å; M292-F351 HydrophobicContact CG-CD2 4.14Å; M292-F351 HydrophobicContact CG-CG 3.76Å; M292-F351 HydrophobicContact SD-CB 3.77Å
293	T	89.7	Confident	88.8	Confident	0 Å²	0	56.5 Å²	56.5	0%	0	29%	0.286	C	S	.	.	H	α-helix	trans	-64.9	-32	-178.8	58.9	0	0	0	0	112.1	M86 M145 R149 Y236 T289 V290 I296 V297	M86-T293 HydrophobicContact CE-CG2 4.25Å; M145-T293 HydrophobicContact CE-CG2 3.89Å; M145-T293 HydrophobicContact CG-CG2 3.86Å; M145-T293 HydrophobicContact SD-CG2 3.83Å; R149-T293 HydrophobicContact CG-CG2 3.88Å; Y236-T293 WeakPolarHBondContact OH-CB 3.1Å; Y236-T293 PolarHBondContact OH-O 3.37Å; Y236-T293 PolarHBondContact OH-OG1 2.97Å; T289-T293 WeakPolarHBondContact O-CG2 3.35Å; T289-T293 PolarHBondContact O-N 3.35Å; T289-T293 PolarHBondContact O-OG1 2.86Å; V290-T293 PolarHBondContact O-N 2.91Å; V290-T293 PolarHBondContact O-OG1 2.98Å; V290-T293 VanDerWaalsContact O-OG1 3.05Å; T293-I296 PolarHBondContact O-N 3.03Å; T293-V297 WeakPolarHBondContact O-CB 3.24Å; T293-V297 WeakPolarHBondContact O-CG2 3.5Å; T293-V297 PolarHBondContact O-N 3.26Å
294	F	92.3	Very high	89.5	Confident	100 Å²	100	54.3 Å²	54.3	44%	0.439	27%	0.268	S	S	.	.	H	α-helix	trans	-63.2	-45.3	175.4	179	-96.8	0	0	0	111.2	Y236 V290 K291 M292 I296 V297 T298	Y236-F294 HydrophobicContact CD1-CB 4.49Å; Y236-F294 AromaticContact CD1-CD2 3.97Å; Y236-F294 HydrophobicContact CD1-CD2 3.97Å; Y236-F294 HydrophobicContact CD2-CD2 4.37Å; Y236-F294 HydrophobicContact CE1-CB 3.89Å; Y236-F294 HydrophobicContact CE1-CD2 4.15Å; Y236-F294 HydrophobicContact CG-CD2 4.11Å; Y236-F294 WeakPolarHBondContact OH-CA 3.42Å; Y236-F294 PolarHBondContact OH-N 2.66Å; Y236-F294 VanDerWaalsContact OH-N 3.08Å; V290-F294 VanDerWaalsContact O-CB 3.3Å; V290-F294 WeakPolarHBondContact O-CB 3.34Å; V290-F294 PolarHBondContact O-N 3.25Å; K291-F294 PolarHBondContact O-N 2.92Å; M292-F294 VanDerWaalsContact C-N 3.25Å; M292-F294 PolarHBondContact O-N 3.46Å; F294-I296 VanDerWaalsContact C-N 3.34Å; F294-I296 PolarHBondContact O-N 2.73Å; F294-V297 PolarHBondContact O-N 3.29Å; F294-T298 PolarHBondContact O-N 3.36Å; F294-T298 PolarHBondContact O-OG1 3.01Å; F294-T298 VanDerWaalsContact O-OG1 3.1Å
295	V	93.1	Very high	90.1	Very high	56 Å²	56	44.1 Å²	44.1	34%	0.339	23%	0.233	S	C	.	.	H	α-helix	trans	-60.7	-43.3	176.2	174.6	0	0	0	0	111.4	K291 M292 V297 T298 A299 I347 F351	K291-V295 WeakPolarHBondContact O-CG2 3.23Å; K291-V295 PolarHBondContact O-N 3.3Å; M292-V295 PolarHBondContact O-N 3.48Å; V295-V297 VanDerWaalsContact C-N 3.31Å; V295-V297 PolarHBondContact O-N 3.01Å; V295-T298 PolarHBondContact O-N 3.12Å; V295-A299 PolarHBondContact O-N 2.87Å; V295-I347 HydrophobicContact CB-CG2 4.35Å; V295-I347 HydrophobicContact CG1-CD1 3.98Å; V295-I347 HydrophobicContact CG1-CG1 3.99Å; V295-I347 HydrophobicContact CG1-CG2 4.14Å; V295-F351 HydrophobicContact CB-CE2 4.25Å; V295-F351 HydrophobicContact CG1-CE2 4.5Å; V295-F351 HydrophobicContact CG2-CE2 3.89Å; V295-F351 HydrophobicContact CG2-CZ 3.81Å
296	I	91.7	Very high	90.8	Very high	0 Å²	0	43.2 Å²	43.2	0%	0	22%	0.222	C	C	.	.	H	α-helix	trans	-59.3	-44.7	176.3	-61.9	171.5	0	0	0	110.8	L142 M145 M292 T293 F294 A299 Y300 I347 Y348	L142-I296 HydrophobicContact CD2-CB 4.49Å; L142-I296 HydrophobicContact CD2-CG2 3.28Å; M145-I296 HydrophobicContact CE-CD1 3.97Å; M145-I296 HydrophobicContact CE-CG2 4.42Å; M292-I296 HydrophobicContact CG-CD1 4.34Å; M292-I296 WeakPolarHBondContact O-CG1 3.36Å; M292-I296 PolarHBondContact O-N 3.43Å; M292-I296 VanDerWaalsContact O-N 3.15Å; T293-I296 PolarHBondContact O-N 3.03Å; F294-I296 VanDerWaalsContact C-N 3.34Å; F294-I296 PolarHBondContact O-N 2.73Å; I296-A299 PolarHBondContact O-N 3.2Å; I296-Y300 PolarHBondContact O-N 3.46Å; I296-I347 HydrophobicContact CB-CD1 4.44Å; I296-I347 HydrophobicContact CD1-CG2 4.29Å; I296-I347 HydrophobicContact CG1-CB 4.24Å; I296-I347 HydrophobicContact CG1-CD1 3.86Å; I296-I347 HydrophobicContact CG1-CG2 3.68Å; I296-Y348 HydrophobicContact CD1-CD1 4.43Å; I296-Y348 HydrophobicContact CD1-CE1 3.56Å
297	V	91.8	Very high	91.3	Very high	5 Å²	5	40.7 Å²	40.7	3%	0.03	21%	0.211	C	C	.	.	H	α-helix	trans	-68.7	-39.4	-178.2	163.3	0	0	0	0	112.1	L232 Y236 T293 F294 V295 Y300 I301	L232-V297 HydrophobicContact CB-CG1 4.01Å; L232-V297 HydrophobicContact CD1-CG1 3.86Å; L232-V297 HydrophobicContact CD1-CG2 4.04Å; L232-V297 HydrophobicContact CD2-CG1 4.47Å; L232-V297 HydrophobicContact CD2-CG2 3.8Å; L232-V297 HydrophobicContact CG-CG1 4.33Å; L232-V297 HydrophobicContact CG-CG2 4.43Å; Y236-V297 HydrophobicContact CD2-CG1 4.3Å; Y236-V297 HydrophobicContact CE2-CB 3.85Å; Y236-V297 HydrophobicContact CE2-CG1 3.84Å; Y236-V297 HydrophobicContact CE2-CG2 3.83Å; T293-V297 WeakPolarHBondContact O-CB 3.24Å; T293-V297 WeakPolarHBondContact O-CG2 3.5Å; T293-V297 PolarHBondContact O-N 3.26Å; F294-V297 PolarHBondContact O-N 3.29Å; V295-V297 VanDerWaalsContact C-N 3.31Å; V295-V297 PolarHBondContact O-N 3.01Å; V297-Y300 PolarHBondContact O-N 3.37Å; V297-I301 HydrophobicContact CG1-CD1 4.17Å; V297-I301 WeakPolarHBondContact O-CG1 3.28Å; V297-I301 PolarHBondContact O-N 3.42Å
298	T	93.2	Very high	91.7	Very high	59 Å²	59	38.2 Å²	38.2	36%	0.362	20%	0.198	S	C	.	.	H	α-helix	trans	-62.6	-43.6	173.8	-58.8	0	0	0	0	111.3	F294 V295 Y300 I301 V302	F294-T298 PolarHBondContact O-N 3.36Å; F294-T298 PolarHBondContact O-OG1 3.01Å; F294-T298 VanDerWaalsContact O-OG1 3.1Å; V295-T298 PolarHBondContact O-N 3.12Å; T298-Y300 VanDerWaalsContact C-N 3.33Å; T298-Y300 PolarHBondContact O-N 3.07Å; T298-I301 PolarHBondContact O-N 2.97Å; T298-V302 HydrophobicContact CG2-CG2 4.33Å; T298-V302 WeakPolarHBondContact O-CG2 3.27Å; T298-V302 PolarHBondContact O-N 3.14Å
299	A	93.7	Very high	92	Very high	20 Å²	20	37.1 Å²	37.1	17%	0.165	20%	0.201	C	C	.	.	H	α-helix	trans	-59.1	-45.6	175.9	0	0	0	0	0	111.2	V295 I296 I301 V302 C303 I347	V295-A299 PolarHBondContact O-N 2.87Å; I296-A299 PolarHBondContact O-N 3.2Å; A299-I301 PolarHBondContact O-N 3.39Å; A299-V302 PolarHBondContact O-N 3.3Å; A299-C303 VanDerWaalsContact O-CB 3.26Å; A299-C303 WeakPolarHBondContact O-CB 3.3Å; A299-C303 PolarHBondContact O-N 3.26Å; A299-C303 PolarHBondContact O-SG 3.47Å; A299-I347 HydrophobicContact CB-CD1 4.48Å
300	Y	94.2	Very high	92.1	Very high	2 Å²	2	36.9 Å²	36.9	1%	0.008	20%	0.198	C	C	.	.	H	α-helix	trans	-57.2	-46.2	175.5	164	-94	0	0	0	112.9	A139 L142 I224 F225 P228 V229 L232 I296 V297 T298 W304 N340	A139-Y300 HydrophobicContact CB-CE2 4.17Å; L142-Y300 HydrophobicContact CD1-CD1 4.31Å; L142-Y300 HydrophobicContact CD1-CD2 3.74Å; L142-Y300 HydrophobicContact CD1-CE2 4.5Å; L142-Y300 HydrophobicContact CD1-CG 3.64Å; I224-Y300 PolarHBondContact O-OH 3.36Å; F225-Y300 WeakPolarHBondContact CA-OH 3.4Å; F225-Y300 HydrophobicContact CD2-CE1 4.45Å; P228-Y300 HydrophobicContact CB-CE1 4.43Å; V229-Y300 HydrophobicContact CG2-CE1 4.05Å; L232-Y300 HydrophobicContact CD1-CD1 4.34Å; L232-Y300 HydrophobicContact CD1-CE1 4.36Å; I296-Y300 PolarHBondContact O-N 3.46Å; V297-Y300 PolarHBondContact O-N 3.37Å; T298-Y300 VanDerWaalsContact C-N 3.33Å; T298-Y300 PolarHBondContact O-N 3.07Å; Y300-W304 AromaticContact CD2-CD1 3.39Å; Y300-W304 HydrophobicContact CD2-CG 4.32Å; Y300-W304 AromaticContact CD2-NE1 3.94Å; Y300-W304 AromaticContact CE2-CD1 3.53Å; Y300-W304 HydrophobicContact CE2-CG 4.12Å; Y300-W304 WeakPolarHBondContact O-CB 3.33Å; Y300-W304 PolarHBondContact O-N 2.97Å; Y300-N340 WeakPolarHBondContact CA-OD1 3.25Å; Y300-N340 PolarHBondContact N-OD1 2.99Å
301	I	94.4	Very high	92	Very high	57 Å²	57	37.2 Å²	37.2	29%	0.292	20%	0.199	S	C	.	.	H	α-helix	trans	-63.6	-48.9	178.5	-66	169.9	0	0	0	110.7	V229 V297 T298 A299 C303 W304 A305	V229-I301 HydrophobicContact CG1-CD1 4.41Å; V229-I301 HydrophobicContact CG2-CD1 4.48Å; V229-I301 HydrophobicContact CG2-CG1 3.97Å; V297-I301 HydrophobicContact CG1-CD1 4.17Å; V297-I301 WeakPolarHBondContact O-CG1 3.28Å; V297-I301 PolarHBondContact O-N 3.42Å; T298-I301 PolarHBondContact O-N 2.97Å; A299-I301 PolarHBondContact O-N 3.39Å; I301-C303 VanDerWaalsContact C-N 3.31Å; I301-C303 PolarHBondContact O-N 3Å; I301-W304 PolarHBondContact O-N 3.24Å; I301-A305 WeakPolarHBondContact O-CB 3.04Å; I301-A305 PolarHBondContact O-N 3.44Å
302	V	94.4	Very high	92	Very high	91 Å²	91	33.5 Å²	33.5	55%	0.552	18%	0.184	S	C	*	.	H	α-helix	trans	-63.6	-38.5	-177.9	171.7	0	0	0	0	111.6	T298 A299 P306	T298-V302 HydrophobicContact CG2-CG2 4.33Å; T298-V302 WeakPolarHBondContact O-CG2 3.27Å; T298-V302 PolarHBondContact O-N 3.14Å; A299-V302 PolarHBondContact O-N 3.3Å; V302-P306 VanDerWaalsContact O-CD 3.28Å; V302-P306 WeakPolarHBondContact O-CD 3.27Å
303	C	93.6	Very high	91.9	Very high	11 Å²	11	40.1 Å²	40.1	7%	0.074	21%	0.209	C	C	.	.	H	α-helix	trans	-72.5	-42.1	-179.9	-74.4	0	0	0	0	112.9	A299 I301 L336 G337 N340	A299-C303 VanDerWaalsContact O-CB 3.26Å; A299-C303 WeakPolarHBondContact O-CB 3.3Å; A299-C303 PolarHBondContact O-N 3.26Å; A299-C303 PolarHBondContact O-SG 3.47Å; I301-C303 VanDerWaalsContact C-N 3.31Å; I301-C303 PolarHBondContact O-N 3Å; C303-L336 WeakPolarHBondContact CB-O 3.18Å; C303-L336 CarbonylContact O-C 3.49Å; C303-G337 WeakPolarHBondContact O-CA 2.96Å; C303-G337 PolarHBondContact O-N 3.15Å; C303-N340 HydrophobicContact CB-CB 3.89Å
304	W	93.3	Very high	91.6	Very high	17 Å²	17	42 Å²	42	6%	0.064	22%	0.222	C	C	.	.	H	α-helix	trans	-93.2	-27	-172.7	-78	102.6	0	0	0	114.8	M135 F225 Y300 I301 F307 F308	M135-W304 HydrophobicContact CE-CE3 4.32Å; M135-W304 HydrophobicContact CE-CH2 3.32Å; M135-W304 HydrophobicContact CE-CZ2 4.24Å; M135-W304 HydrophobicContact CE-CZ3 3.38Å; M135-W304 HydrophobicContact CG-CH2 4.29Å; M135-W304 HydrophobicContact SD-CH2 4.22Å; F225-W304 HydrophobicContact CD2-CB 4.02Å; F225-W304 HydrophobicContact CE2-CB 4.23Å; Y300-W304 AromaticContact CD2-CD1 3.39Å; Y300-W304 HydrophobicContact CD2-CG 4.32Å; Y300-W304 AromaticContact CD2-NE1 3.94Å; Y300-W304 AromaticContact CE2-CD1 3.53Å; Y300-W304 HydrophobicContact CE2-CG 4.12Å; Y300-W304 WeakPolarHBondContact O-CB 3.33Å; Y300-W304 PolarHBondContact O-N 2.97Å; I301-W304 PolarHBondContact O-N 3.24Å; W304-F307 HydrophobicContact CE3-CD1 4.08Å; W304-F307 AromaticContact CZ3-CD1 3.98Å; W304-F307 HydrophobicContact CZ3-CD1 3.98Å; W304-F307 HydrophobicContact CZ3-CE1 4.36Å; W304-F307 PolarHBondContact O-N 2.76Å; W304-F308 HydrophobicContact CB-CD2 4.02Å; W304-F308 HydrophobicContact CB-CE2 4.04Å; W304-F308 AromaticContact CD2-CE2 3.95Å; W304-F308 HydrophobicContact CD2-CE2 3.95Å; W304-F308 HydrophobicContact CE3-CD2 4.06Å; W304-F308 AromaticContact CE3-CE2 3.37Å; W304-F308 HydrophobicContact CE3-CE2 3.37Å; W304-F308 HydrophobicContact CE3-CZ 4.02Å; W304-F308 HydrophobicContact CG-CE2 4.27Å; W304-F308 HydrophobicContact CZ3-CE2 4.1Å; W304-F308 HydrophobicContact CZ3-CZ 4.31Å; W304-F308 VanDerWaalsContact O-CD2 3.31Å; W304-F308 WeakPolarHBondContact O-CD2 3.12Å; W304-F308 PolarHBondContact O-N 2.92Å
305	A	94.6	Very high	91.1	Very high	17 Å²	17	38.4 Å²	38.4	14%	0.14	21%	0.208	C	C	.	.	H	α-helix	trans	-56.3	-46.7	-175.8	0	0	0	0	0	113.1	F225 I301 F307 F308 I309	F225-A305 HydrophobicContact CE1-CB 4.44Å; F225-A305 HydrophobicContact CE2-CB 4Å; F225-A305 HydrophobicContact CZ-CB 3.55Å; I301-A305 WeakPolarHBondContact O-CB 3.04Å; I301-A305 PolarHBondContact O-N 3.44Å; A305-F307 VanDerWaalsContact C-N 3.33Å; A305-F307 PolarHBondContact O-N 3.11Å; A305-F308 PolarHBondContact O-N 3.48Å; A305-I309 HydrophobicContact CB-CD1 4.31Å; A305-I309 WeakPolarHBondContact O-CB 3.38Å; A305-I309 WeakPolarHBondContact O-CD1 3.29Å; A305-I309 WeakPolarHBondContact O-CG1 2.94Å; A305-I309 PolarHBondContact O-N 3.32Å
306	P	93.3	Very high	90.8	Very high	43 Å²	43	42.6 Å²	42.6	28%	0.279	22%	0.218	S	C	.	.	H	α-helix	trans	-59.6	-44.1	-177.9	-27.4	39.5	0	0	0	112.4	V302 I309 I310 T333 L336	V302-P306 VanDerWaalsContact O-CD 3.28Å; V302-P306 WeakPolarHBondContact O-CD 3.27Å; P306-I309 PolarHBondContact O-N 3.22Å; P306-I310 WeakPolarHBondContact O-CD1 3.05Å; P306-I310 WeakPolarHBondContact O-CG1 3.27Å; P306-I310 PolarHBondContact O-N 3.3Å; P306-T333 HydrophobicContact CB-CG2 3.68Å; P306-L336 HydrophobicContact CB-CD2 4.33Å; P306-L336 HydrophobicContact CG-CD2 3.79Å
307	F	90.8	Very high	90.4	Very high	21 Å²	21	45.1 Å²	45.1	9%	0.092	23%	0.231	C	C	.	.	H	α-helix	trans	-60.4	-51	178.5	177.1	-105.6	0	0	0	111.7	W304 A305 I309 I310 Q311 A334	W304-F307 HydrophobicContact CE3-CD1 4.08Å; W304-F307 AromaticContact CZ3-CD1 3.98Å; W304-F307 HydrophobicContact CZ3-CD1 3.98Å; W304-F307 HydrophobicContact CZ3-CE1 4.36Å; W304-F307 PolarHBondContact O-N 2.76Å; A305-F307 VanDerWaalsContact C-N 3.33Å; A305-F307 PolarHBondContact O-N 3.11Å; F307-I309 PolarHBondContact O-N 2.85Å; F307-I310 PolarHBondContact O-N 3.08Å; F307-Q311 HydrophobicContact CD1-CG 4.22Å; F307-Q311 HydrophobicContact CD2-CG 4.09Å; F307-Q311 HydrophobicContact CE1-CG 3.86Å; F307-Q311 HydrophobicContact CE2-CG 3.71Å; F307-Q311 HydrophobicContact CG-CG 4.34Å; F307-Q311 HydrophobicContact CZ-CG 3.59Å; F307-Q311 WeakPolarHBondContact O-CB 3.26Å; F307-Q311 WeakPolarHBondContact O-CG 3.49Å; F307-Q311 PolarHBondContact O-N 3.37Å; F307-A334 HydrophobicContact CD2-CB 3.83Å; F307-A334 HydrophobicContact CE2-CB 3.86Å
308	F	91.8	Very high	89.3	Confident	6 Å²	6	50.1 Å²	50.1	3%	0.026	26%	0.264	C	S	.	.	H	α-helix	trans	-68.9	-33.1	-177.7	-75.9	-65.5	0	0	0	113.2	M135 T221 I224 F225 W304 A305 M312	M135-F308 HydrophobicContact CE-CZ 4.03Å; T221-F308 HydrophobicContact CG2-CB 3.94Å; T221-F308 HydrophobicContact CG2-CD1 3.9Å; T221-F308 HydrophobicContact CG2-CG 4.17Å; T221-F308 WeakPolarHBondContact OG1-CD1 3.22Å; I224-F308 HydrophobicContact CB-CE1 4.42Å; I224-F308 HydrophobicContact CB-CZ 3.8Å; I224-F308 HydrophobicContact CG2-CE2 4.04Å; I224-F308 HydrophobicContact CG2-CZ 3.57Å; F225-F308 HydrophobicContact CB-CB 4.38Å; F225-F308 HydrophobicContact CB-CD1 4.34Å; F225-F308 HydrophobicContact CB-CD2 3.39Å; F225-F308 HydrophobicContact CB-CE2 3.63Å; F225-F308 HydrophobicContact CB-CG 3.78Å; F225-F308 HydrophobicContact CB-CZ 4.2Å; F225-F308 HydrophobicContact CD1-CB 4.07Å; F225-F308 HydrophobicContact CD1-CD2 4.31Å; F225-F308 HydrophobicContact CD1-CG 4.38Å; F225-F308 AromaticContact CD2-CD2 3.83Å; F225-F308 HydrophobicContact CD2-CD2 3.83Å; F225-F308 HydrophobicContact CD2-CE2 4.35Å; F225-F308 HydrophobicContact CG-CB 4.21Å; F225-F308 AromaticContact CG-CD2 3.59Å; F225-F308 HydrophobicContact CG-CD2 3.59Å; F225-F308 HydrophobicContact CG-CE2 4.22Å; F225-F308 HydrophobicContact CG-CG 4.05Å; W304-F308 HydrophobicContact CB-CD2 4.02Å; W304-F308 HydrophobicContact CB-CE2 4.04Å; W304-F308 AromaticContact CD2-CE2 3.95Å; W304-F308 HydrophobicContact CD2-CE2 3.95Å; W304-F308 HydrophobicContact CE3-CD2 4.06Å; W304-F308 AromaticContact CE3-CE2 3.37Å; W304-F308 HydrophobicContact CE3-CE2 3.37Å; W304-F308 HydrophobicContact CE3-CZ 4.02Å; W304-F308 HydrophobicContact CG-CE2 4.27Å; W304-F308 HydrophobicContact CZ3-CE2 4.1Å; W304-F308 HydrophobicContact CZ3-CZ 4.31Å; W304-F308 VanDerWaalsContact O-CD2 3.31Å; W304-F308 WeakPolarHBondContact O-CD2 3.12Å; W304-F308 PolarHBondContact O-N 2.92Å; A305-F308 PolarHBondContact O-N 3.48Å; F308-M312 WeakPolarHBondContact O-CB 3.42Å; F308-M312 VanDerWaalsContact O-CG 3.28Å; F308-M312 WeakPolarHBondContact O-CG 3.35Å; F308-M312 PolarHBondContact O-N 3.03Å
309	I	92.2	Very high	88	Confident	103 Å²	103	55 Å²	55	53%	0.528	28%	0.284	S	S	.	.	H	α-helix	trans	-63.3	-49.3	174.2	-70.1	165.6	0	0	0	110.1	A305 P306 F307 M312 W313	A305-I309 HydrophobicContact CB-CD1 4.31Å; A305-I309 WeakPolarHBondContact O-CB 3.38Å; A305-I309 WeakPolarHBondContact O-CD1 3.29Å; A305-I309 WeakPolarHBondContact O-CG1 2.94Å; A305-I309 PolarHBondContact O-N 3.32Å; P306-I309 PolarHBondContact O-N 3.22Å; F307-I309 PolarHBondContact O-N 2.85Å; I309-M312 PolarHBondContact O-N 3.47Å; I309-W313 WeakPolarHBondContact O-CB 3.15Å; I309-W313 PolarHBondContact O-N 2.92Å
310	I	88.2	Confident	86.5	Confident	23 Å²	23	55.3 Å²	55.3	12%	0.118	29%	0.286	C	S	.	.	H	α-helix	trans	-65.1	-42.3	179.8	-72.7	155.7	0	0	0	111.3	P306 F307 M312 W313 S314 T329 I330 T333	P306-I310 WeakPolarHBondContact O-CD1 3.05Å; P306-I310 WeakPolarHBondContact O-CG1 3.27Å; P306-I310 PolarHBondContact O-N 3.3Å; F307-I310 PolarHBondContact O-N 3.08Å; I310-M312 VanDerWaalsContact C-N 3.33Å; I310-M312 PolarHBondContact O-N 3.18Å; I310-W313 PolarHBondContact O-N 2.65Å; I310-S314 WeakPolarHBondContact O-CB 3.48Å; I310-S314 PolarHBondContact O-N 3.36Å; I310-T329 HydrophobicContact CD1-CG2 3.58Å; I310-T329 HydrophobicContact CG1-CG2 4.42Å; I310-I330 HydrophobicContact CG2-CG1 3.84Å; I310-T333 HydrophobicContact CD1-CG2 3.29Å
311	Q	87.1	Confident	84.7	Confident	20 Å²	20	61.1 Å²	61.1	9%	0.093	32%	0.321	C	S	.	.	H	α-helix	trans	-61.9	-40.5	177.2	-72.5	-71.1	103.2	0	0	112.2	V217 F307 V315	V217-Q311 HydrophobicContact CG1-CB 4.06Å; F307-Q311 HydrophobicContact CD1-CG 4.22Å; F307-Q311 HydrophobicContact CD2-CG 4.09Å; F307-Q311 HydrophobicContact CE1-CG 3.86Å; F307-Q311 HydrophobicContact CE2-CG 3.71Å; F307-Q311 HydrophobicContact CG-CG 4.34Å; F307-Q311 HydrophobicContact CZ-CG 3.59Å; F307-Q311 WeakPolarHBondContact O-CB 3.26Å; F307-Q311 WeakPolarHBondContact O-CG 3.49Å; F307-Q311 PolarHBondContact O-N 3.37Å; Q311-V315 WeakPolarHBondContact O-CG2 3.26Å; Q311-V315 PolarHBondContact O-N 3.39Å
312	M	89.4	Confident	82.7	Confident	48 Å²	48	62 Å²	62	24%	0.236	32%	0.321	C	S	.	.	H	α-helix	trans	-68.4	-42.6	175.3	-72.4	-62.7	-126.4	0	0	111.6	V217 T218 T221 F308 I309 I310 V315 W316	V217-M312 HydrophobicContact CG1-SD 4.13Å; T218-M312 HydrophobicContact CG2-CE 4.1Å; T221-M312 HydrophobicContact CG2-CE 3.6Å; T221-M312 HydrophobicContact CG2-CG 3.76Å; T221-M312 HydrophobicContact CG2-SD 4.12Å; F308-M312 WeakPolarHBondContact O-CB 3.42Å; F308-M312 VanDerWaalsContact O-CG 3.28Å; F308-M312 WeakPolarHBondContact O-CG 3.35Å; F308-M312 PolarHBondContact O-N 3.03Å; I309-M312 PolarHBondContact O-N 3.47Å; I310-M312 VanDerWaalsContact C-N 3.33Å; I310-M312 PolarHBondContact O-N 3.18Å; M312-V315 PolarHBondContact O-N 3.5Å; M312-W316 WeakPolarHBondContact O-CB 3.32Å; M312-W316 VanDerWaalsContact O-CD1 3.3Å; M312-W316 PolarHBondContact O-N 2.68Å; M312-W316 VanDerWaalsContact O-N 3.09Å
313	W	87.9	Confident	80.6	Confident	144 Å²	144	62.4 Å²	62.4	55%	0.545	32%	0.324	S	S	.	.	H	α-helix	trans	-58	-52.4	176.5	-168.3	-16.6	0	0	0	110.6	I309 I310 V315 W316 D317	I309-W313 WeakPolarHBondContact O-CB 3.15Å; I309-W313 PolarHBondContact O-N 2.92Å; I310-W313 PolarHBondContact O-N 2.65Å; W313-V315 PolarHBondContact O-N 2.77Å; W313-W316 PolarHBondContact O-N 2.01Å; W313-D317 VanDerWaalsContact CD1-CB 3.42Å; W313-D317 PolarHBondContact NE1-OD2 2.97Å; W313-D317 WeakPolarHBondContact O-CB 3.48Å; W313-D317 PolarHBondContact O-N 2.89Å
314	S	81.9	Confident	78.6	Confident	39 Å²	39	67.1 Å²	67.1	27%	0.273	35%	0.345	S	S	.	.	H	α-helix	trans	-55.2	-25.1	-178.3	171	0	0	0	0	114.3	I310	I310-S314 WeakPolarHBondContact O-CB 3.48Å; I310-S314 PolarHBondContact O-N 3.36Å
315	V	83.3	Confident	76.7	Confident	25 Å²	25	68.9 Å²	68.9	15%	0.152	36%	0.359	C	S	.	.	H	α-helix	trans	-103.3	-25.9	-172.6	172.5	0	0	0	0	112.9	R214 V217 Q311 M312 W313	R214-V315 HydrophobicContact CB-CG1 3.9Å; R214-V315 HydrophobicContact CG-CG1 3.5Å; R214-V315 PolarHBondContact NE-O 3.42Å; V217-V315 HydrophobicContact CB-CG1 4.34Å; V217-V315 HydrophobicContact CB-CG2 4.1Å; V217-V315 HydrophobicContact CG1-CB 4.5Å; V217-V315 HydrophobicContact CG1-CG2 4.11Å; V217-V315 HydrophobicContact CG2-CG2 3.92Å; Q311-V315 WeakPolarHBondContact O-CG2 3.26Å; Q311-V315 PolarHBondContact O-N 3.39Å; M312-V315 PolarHBondContact O-N 3.5Å; W313-V315 PolarHBondContact O-N 2.77Å
316	W	86.1	Confident	74.8	Confident	144 Å²	144	72.3 Å²	72.3	55%	0.545	37%	0.373	S	S	.	.	H	α-helix	trans	-101.1	-18.4	-178.4	-73.8	101	0	0	0	114.2	R214 T218 M312 W313 P318	R214-W316 HydrophobicContact CB-CZ2 4.42Å; T218-W316 WeakPolarHBondContact OG1-CZ2 3.47Å; T218-W316 PolarHBondContact OG1-NE1 3.45Å; T218-W316 VanDerWaalsContact OG1-NE1 3.1Å; M312-W316 WeakPolarHBondContact O-CB 3.32Å; M312-W316 VanDerWaalsContact O-CD1 3.3Å; M312-W316 PolarHBondContact O-N 2.68Å; M312-W316 VanDerWaalsContact O-N 3.09Å; W313-W316 PolarHBondContact O-N 2.01Å; W316-P318 WeakPolarHBondContact O-CD 2.6Å
317	D	82.7	Confident	73.6	Confident	53 Å²	53	72.1 Å²	72.1	28%	0.283	37%	0.369	S	S	.	.			trans	-96.6	105.7	175.4	-175.1	1.2	0	0	0	111.4	W313 M319 S320	W313-D317 VanDerWaalsContact CD1-CB 3.42Å; W313-D317 PolarHBondContact NE1-OD2 2.97Å; W313-D317 WeakPolarHBondContact O-CB 3.48Å; W313-D317 PolarHBondContact O-N 2.89Å; D317-M319 PolarHBondContact O-N 2.96Å; D317-M319 WeakPolarHBondContact OD1-CB 3.32Å; D317-M319 PolarHBondContact OD1-N 3.47Å; D317-S320 PolarHBondContact O-N 2.81Å; D317-S320 PolarHBondContact O-OG 2.95Å
318	P	68.7	Low	73	Confident	109 Å²	109	74 Å²	74	71%	0.708	38%	0.384	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.7	-20.7	-180	-14.3	30.1	0	0	0	113.5	W316 S320	W316-P318 WeakPolarHBondContact O-CD 2.6Å; P318-S320 VanDerWaalsContact C-N 3.29Å
319	M	66.1	Low	72.5	Confident	161 Å²	161	76.5 Å²	76.5	79%	0.793	40%	0.4	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.7	-8.6	-179	-68	-62.5	-61.3	0	0	112.6	D317 V321	D317-M319 PolarHBondContact O-N 2.96Å; D317-M319 WeakPolarHBondContact OD1-CB 3.32Å; D317-M319 PolarHBondContact OD1-N 3.47Å; M319-V321 PolarHBondContact O-N 3.19Å; M319-V321 VanDerWaalsContact O-N 3.15Å
320	S	62	Low	71.9	Confident	28 Å²	28	73.3 Å²	73.3	20%	0.196	38%	0.383	C	S	.	.			trans	-80.6	102.5	-175.9	71.7	0	0	0	0	110.1	D317 P318 W322	D317-S320 PolarHBondContact O-N 2.81Å; D317-S320 PolarHBondContact O-OG 2.95Å; P318-S320 VanDerWaalsContact C-N 3.29Å; S320-W322 PolarHBondContact O-N 2.88Å
321	V	56	Low	71.4	Confident	124 Å²	124	72.8 Å²	72.8	75%	0.752	38%	0.381	S	S	*	.			trans	-72.8	59.9	171.2	-169.4	0	0	0	0	108.8	M319 T323	M319-V321 PolarHBondContact O-N 3.19Å; M319-V321 VanDerWaalsContact O-N 3.15Å; V321-T323 HydrophobicContact CG1-CG2 4.3Å; V321-T323 PolarHBondContact O-N 2.93Å
322	W	53.9	Low	71.3	Confident	74 Å²	74	76.8 Å²	76.8	28%	0.28	40%	0.402	S	S	.	.			trans	-79.8	82.4	162.9	-58.5	100.7	0	0	0	105.9	S320 E324 N327	S320-W322 PolarHBondContact O-N 2.88Å; W322-E324 VanDerWaalsContact C-N 3.31Å; W322-E324 PolarHBondContact O-N 2.9Å; W322-N327 HydrophobicContact CE3-CB 3.99Å; W322-N327 VanDerWaalsContact CE3-CG 3.47Å; W322-N327 HydrophobicContact CZ3-CB 4.36Å; W322-N327 VanDerWaalsContact CZ3-CG 3.41Å; W322-N327 WeakPolarHBondContact CZ3-ND2 3.29Å
323	T	50.1	Low	71.2	Confident	101 Å²	101	75 Å²	75	62%	0.62	39%	0.394	S	S	*	.			trans	-54.8	100.6	166.6	20.5	0	0	0	0	108.4	V321	V321-T323 HydrophobicContact CG1-CG2 4.3Å; V321-T323 PolarHBondContact O-N 2.93Å
324	E	51.8	Low	71	Confident	109 Å²	109	69.9 Å²	69.9	51%	0.509	38%	0.382	S	S	.	.	T	Hydrogen-bonded Turn	trans	31.6	96.3	141.1	-57.9	-139	123.5	0	0	115.5	S4 A5 W322 E326	S4-E324 WeakPolarHBondContact CA-OE1 3.12Å; S4-E324 WeakPolarHBondContact CB-OE1 3.47Å; S4-E324 WeakPolarHBondContact OG-CA 3.48Å; S4-E324 WeakPolarHBondContact OG-CB 3.44Å; S4-E324 WeakPolarHBondContact OG-CG 3.28Å; S4-E324 PolarHBondContact OG-OE1 3.37Å; A5-E324 PolarHBondContact N-OE1 3.47Å; W322-E324 VanDerWaalsContact C-N 3.31Å; W322-E324 PolarHBondContact O-N 2.9Å; E324-E326 VanDerWaalsContact C-N 3.26Å; E324-E326 PolarHBondContact O-N 3.49Å
325	S	51.7	Low	71.1	Confident	54 Å²	54	68.9 Å²	68.9	38%	0.378	37%	0.374	S	S	.	.	T	Hydrogen-bonded Turn	trans	67.1	-15.9	160.4	77.5	0	0	0	0	120.4
326	E	55.3	Low	71.4	Confident	89 Å²	89	70.4 Å²	70.4	42%	0.416	38%	0.381	S	S	.	.			trans	-103.1	0.7	-175.3	-63.9	-146.5	120.1	0	0	115.1	R46 N47 E324 P328	R46-E326 WeakPolarHBondContact CA-OE1 3.43Å; N47-E326 PolarHBondContact N-OE1 2.84Å; E324-E326 VanDerWaalsContact C-N 3.26Å; E324-E326 PolarHBondContact O-N 3.49Å; E326-P328 VanDerWaalsContact O-CD 3.23Å; E326-P328 WeakPolarHBondContact O-CD 3.46Å; E326-P328 VanDerWaalsContact O-N 3.17Å
327	N	69.1	Low	71.5	Confident	40 Å²	40	63.6 Å²	63.6	21%	0.214	36%	0.355	C	S	.	.			trans	-71.5	116	-178	-162.5	-62.6	0	0	0	111	W322 T329 I330 T331	W322-N327 HydrophobicContact CE3-CB 3.99Å; W322-N327 VanDerWaalsContact CE3-CG 3.47Å; W322-N327 HydrophobicContact CZ3-CB 4.36Å; W322-N327 VanDerWaalsContact CZ3-CG 3.41Å; W322-N327 WeakPolarHBondContact CZ3-ND2 3.29Å; N327-T329 PolarHBondContact O-N 3.47Å; N327-T329 WeakPolarHBondContact OD1-CB 3.2Å; N327-T329 PolarHBondContact OD1-N 3.4Å; N327-T329 PolarHBondContact OD1-OG1 2.62Å; N327-T329 VanDerWaalsContact OD1-OG1 3.08Å; N327-I330 HydrophobicContact CB-CD1 4.37Å; N327-I330 HydrophobicContact CB-CG1 4.41Å; N327-I330 PolarHBondContact O-N 3.13Å; N327-T331 PolarHBondContact O-N 3.47Å
328	P	77.2	Confident	71.6	Confident	61 Å²	61	61.3 Å²	61.3	40%	0.396	34%	0.343	S	S	.	.	H	α-helix	trans	-57.9	-26.4	-178.4	24.2	-34.7	0	0	0	112.1	L50 E326 T331 I332	L50-P328 HydrophobicContact CD1-CB 4.13Å; L50-P328 HydrophobicContact CD2-CB 4.17Å; E326-P328 VanDerWaalsContact O-CD 3.23Å; E326-P328 WeakPolarHBondContact O-CD 3.46Å; E326-P328 VanDerWaalsContact O-N 3.17Å; P328-T331 PolarHBondContact O-N 3.49Å; P328-I332 HydrophobicContact CB-CD1 4.3Å; P328-I332 VanDerWaalsContact O-CB 3.27Å; P328-I332 WeakPolarHBondContact O-CB 3.44Å; P328-I332 WeakPolarHBondContact O-CD1 3.37Å; P328-I332 WeakPolarHBondContact O-CG1 3.28Å; P328-I332 PolarHBondContact O-N 3.21Å
329	T	81.1	Confident	72.5	Confident	58 Å²	58	59.4 Å²	59.4	36%	0.356	33%	0.327	S	S	.	.	H	α-helix	trans	-63.1	-41.9	176.7	-55	0	0	0	0	112.4	I310 N327 T333	I310-T329 HydrophobicContact CD1-CG2 3.58Å; I310-T329 HydrophobicContact CG1-CG2 4.42Å; N327-T329 PolarHBondContact O-N 3.47Å; N327-T329 WeakPolarHBondContact OD1-CB 3.2Å; N327-T329 PolarHBondContact OD1-N 3.4Å; N327-T329 PolarHBondContact OD1-OG1 2.62Å; N327-T329 VanDerWaalsContact OD1-OG1 3.08Å; T329-T333 WeakPolarHBondContact O-CB 3.38Å; T329-T333 VanDerWaalsContact O-CG2 3.29Å; T329-T333 WeakPolarHBondContact O-CG2 3.23Å; T329-T333 PolarHBondContact O-N 3.06Å; T329-T333 PolarHBondContact O-OG1 3.39Å
330	I	80	Confident	73.6	Confident	36 Å²	36	51.8 Å²	51.8	19%	0.185	29%	0.289	C	S	.	.	H	α-helix	trans	-66.8	-44.7	177.5	-63.1	175	0	0	0	109.6	I310 N327 T333 A334	I310-I330 HydrophobicContact CG2-CG1 3.84Å; N327-I330 HydrophobicContact CB-CD1 4.37Å; N327-I330 HydrophobicContact CB-CG1 4.41Å; N327-I330 PolarHBondContact O-N 3.13Å; I330-T333 PolarHBondContact O-N 3.36Å; I330-T333 PolarHBondContact O-OG1 2.88Å; I330-T333 VanDerWaalsContact O-OG1 3.11Å; I330-A334 WeakPolarHBondContact O-CB 3.46Å; I330-A334 PolarHBondContact O-N 3.43Å
331	T	78.8	Confident	74.8	Confident	12 Å²	12	50.7 Å²	50.7	7%	0.074	28%	0.281	C	S	.	.	H	α-helix	trans	-61.1	-51.5	177.5	-57	0	0	0	0	111.4	L50 E54 N327 P328 T333 A334 L335	L50-T331 HydrophobicContact CD1-CG2 4.44Å; E54-T331 HydrophobicContact CB-CG2 4.06Å; E54-T331 HydrophobicContact CG-CG2 3.93Å; N327-T331 PolarHBondContact O-N 3.47Å; P328-T331 PolarHBondContact O-N 3.49Å; T331-T333 VanDerWaalsContact C-N 3.3Å; T331-T333 PolarHBondContact O-N 2.93Å; T331-A334 PolarHBondContact O-N 2.92Å; T331-L335 HydrophobicContact CG2-CD1 4.08Å; T331-L335 HydrophobicContact CG2-CG 4.41Å; T331-L335 VanDerWaalsContact O-CG 3.26Å; T331-L335 WeakPolarHBondContact O-CG 3.3Å; T331-L335 PolarHBondContact O-N 2.84Å
332	I	83.5	Confident	76.4	Confident	103 Å²	103	45.3 Å²	45.3	53%	0.528	25%	0.249	S	C	.	.	H	α-helix	trans	-58.2	-43.2	180	-70.4	163.5	0	0	0	111.2	P328 L335 L336	P328-I332 HydrophobicContact CB-CD1 4.3Å; P328-I332 VanDerWaalsContact O-CB 3.27Å; P328-I332 WeakPolarHBondContact O-CB 3.44Å; P328-I332 WeakPolarHBondContact O-CD1 3.37Å; P328-I332 WeakPolarHBondContact O-CG1 3.28Å; P328-I332 PolarHBondContact O-N 3.21Å; I332-L335 PolarHBondContact O-N 3.44Å; I332-L336 PolarHBondContact O-N 3.03Å
333	T	86.9	Confident	78.1	Confident	12 Å²	12	43.7 Å²	43.7	7%	0.074	25%	0.249	C	C	.	.	H	α-helix	trans	-73.3	-33.1	-179.8	57.2	0	0	0	0	113	P306 I310 T329 I330 T331 L336 G337	P306-T333 HydrophobicContact CB-CG2 3.68Å; I310-T333 HydrophobicContact CD1-CG2 3.29Å; T329-T333 WeakPolarHBondContact O-CB 3.38Å; T329-T333 VanDerWaalsContact O-CG2 3.29Å; T329-T333 WeakPolarHBondContact O-CG2 3.23Å; T329-T333 PolarHBondContact O-N 3.06Å; T329-T333 PolarHBondContact O-OG1 3.39Å; I330-T333 PolarHBondContact O-N 3.36Å; I330-T333 PolarHBondContact O-OG1 2.88Å; I330-T333 VanDerWaalsContact O-OG1 3.11Å; T331-T333 VanDerWaalsContact C-N 3.3Å; T331-T333 PolarHBondContact O-N 2.93Å; T333-L336 PolarHBondContact O-N 3.32Å; T333-G337 PolarHBondContact O-N 3.23Å; T333-G337 VanDerWaalsContact O-N 3.08Å
334	A	84.7	Confident	79.8	Confident	36 Å²	36	38.9 Å²	38.9	30%	0.298	22%	0.219	S	C	.	.	H	α-helix	trans	-63.7	-42.7	170.2	0	0	0	0	0	111.8	F307 I330 T331 L336 G337 S338	F307-A334 HydrophobicContact CD2-CB 3.83Å; F307-A334 HydrophobicContact CE2-CB 3.86Å; I330-A334 WeakPolarHBondContact O-CB 3.46Å; I330-A334 PolarHBondContact O-N 3.43Å; T331-A334 PolarHBondContact O-N 2.92Å; A334-L336 VanDerWaalsContact C-N 3.34Å; A334-L336 PolarHBondContact O-N 3.19Å; A334-G337 PolarHBondContact O-N 2.93Å; A334-S338 PolarHBondContact O-N 3.11Å; A334-S338 VanDerWaalsContact O-N 3.13Å
335	L	85	Confident	81.4	Confident	17 Å²	17	33.9 Å²	33.9	9%	0.089	20%	0.196	C	C	.	.	H	α-helix	trans	-61.2	-42.6	174.5	-68.2	173.6	0	0	0	111.1	E54 V57 L58 T331 I332 G337 S338 L339	E54-L335 HydrophobicContact CG-CD2 4.38Å; V57-L335 HydrophobicContact CB-CD1 4.11Å; V57-L335 HydrophobicContact CB-CD2 4.12Å; V57-L335 HydrophobicContact CG1-CB 4.24Å; V57-L335 HydrophobicContact CG1-CD1 4.05Å; V57-L335 HydrophobicContact CG1-CD2 3.84Å; V57-L335 HydrophobicContact CG1-CG 4.26Å; V57-L335 HydrophobicContact CG2-CD1 4.4Å; L58-L335 HydrophobicContact CD2-CD2 3.67Å; L58-L335 HydrophobicContact CG-CD2 3.74Å; T331-L335 HydrophobicContact CG2-CD1 4.08Å; T331-L335 HydrophobicContact CG2-CG 4.41Å; T331-L335 VanDerWaalsContact O-CG 3.26Å; T331-L335 WeakPolarHBondContact O-CG 3.3Å; T331-L335 PolarHBondContact O-N 2.84Å; I332-L335 PolarHBondContact O-N 3.44Å; L335-G337 VanDerWaalsContact C-N 3.3Å; L335-G337 PolarHBondContact O-N 3.48Å; L335-S338 WeakPolarHBondContact O-CB 3.24Å; L335-S338 PolarHBondContact O-N 2.97Å; L335-S338 PolarHBondContact O-OG 3.24Å; L335-L339 PolarHBondContact O-N 2.86Å
336	L	89.7	Confident	83	Confident	58 Å²	58	38 Å²	38	30%	0.304	20%	0.204	S	C	.	.	H	α-helix	trans	-59.7	-39.5	175.3	-177.7	62.2	0	0	0	112.4	C303 P306 I332 T333 A334 S338 L339	C303-L336 WeakPolarHBondContact CB-O 3.18Å; C303-L336 CarbonylContact O-C 3.49Å; P306-L336 HydrophobicContact CB-CD2 4.33Å; P306-L336 HydrophobicContact CG-CD2 3.79Å; I332-L336 PolarHBondContact O-N 3.03Å; T333-L336 PolarHBondContact O-N 3.32Å; A334-L336 VanDerWaalsContact C-N 3.34Å; A334-L336 PolarHBondContact O-N 3.19Å; L336-S338 VanDerWaalsContact C-N 3.32Å; L336-S338 PolarHBondContact O-N 3.01Å; L336-L339 HydrophobicContact CD1-CD1 4.2Å; L336-L339 WeakPolarHBondContact O-CB 3.4Å; L336-L339 PolarHBondContact O-N 3.48Å
337	G	87	Confident	84.5	Confident	0 Å²	0	34.5 Å²	34.5	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-61	-39.5	173	0	0	0	0	0	112.7	C303 T333 A334 L335 L339 N340	C303-G337 WeakPolarHBondContact O-CA 2.96Å; C303-G337 PolarHBondContact O-N 3.15Å; T333-G337 PolarHBondContact O-N 3.23Å; T333-G337 VanDerWaalsContact O-N 3.08Å; A334-G337 PolarHBondContact O-N 2.93Å; L335-G337 VanDerWaalsContact C-N 3.3Å; L335-G337 PolarHBondContact O-N 3.48Å; G337-L339 VanDerWaalsContact C-N 3.31Å; G337-L339 PolarHBondContact O-N 3.46Å; G337-N340 VanDerWaalsContact O-CB 3.28Å; G337-N340 WeakPolarHBondContact O-CB 3.21Å; G337-N340 PolarHBondContact O-N 2.87Å
338	S	84.3	Confident	85.1	Confident	6 Å²	6	32.7 Å²	32.7	4%	0.042	18%	0.178	C	C	.	.	H	α-helix	trans	-67.3	-27.7	179.4	74.6	0	0	0	0	113.8	A334 L335 L336 N340 S341	A334-S338 PolarHBondContact O-N 3.11Å; A334-S338 VanDerWaalsContact O-N 3.13Å; L335-S338 WeakPolarHBondContact O-CB 3.24Å; L335-S338 PolarHBondContact O-N 2.97Å; L335-S338 PolarHBondContact O-OG 3.24Å; L336-S338 VanDerWaalsContact C-N 3.32Å; L336-S338 PolarHBondContact O-N 3.01Å; S338-N340 PolarHBondContact O-N 2.91Å; S338-S341 PolarHBondContact O-N 3.45Å
339	L	87.6	Confident	85.2	Confident	68 Å²	68	31.8 Å²	31.8	36%	0.356	17%	0.169	S	C	.	.	T	Hydrogen-bonded Turn	trans	-64.6	-20.6	176.1	-67.7	174.8	0	0	0	113.4	L335 L336 G337 S341 C342 C343	L335-L339 PolarHBondContact O-N 2.86Å; L336-L339 HydrophobicContact CD1-CD1 4.2Å; L336-L339 WeakPolarHBondContact O-CB 3.4Å; L336-L339 PolarHBondContact O-N 3.48Å; G337-L339 VanDerWaalsContact C-N 3.31Å; G337-L339 PolarHBondContact O-N 3.46Å; L339-S341 VanDerWaalsContact C-N 3.25Å; L339-S341 PolarHBondContact O-N 3.47Å; L339-C342 VanDerWaalsContact O-CB 3.31Å; L339-C342 WeakPolarHBondContact O-CB 3.25Å; L339-C342 PolarHBondContact O-N 3.19Å; L339-C343 PolarHBondContact O-N 3.39Å; L339-C343 PolarHBondContact O-SG 3.36Å
340	N	89.7	Confident	85.2	Confident	1 Å²	1	36.5 Å²	36.5	1%	0.005	19%	0.185	C	C	.	.	H	α-helix	trans	-53.6	-42.9	177.9	178.7	60.3	0	0	0	112.3	Y300 C303 G337 S338 C342 C343	Y300-N340 WeakPolarHBondContact CA-OD1 3.25Å; Y300-N340 PolarHBondContact N-OD1 2.99Å; C303-N340 HydrophobicContact CB-CB 3.89Å; G337-N340 VanDerWaalsContact O-CB 3.28Å; G337-N340 WeakPolarHBondContact O-CB 3.21Å; G337-N340 PolarHBondContact O-N 2.87Å; S338-N340 PolarHBondContact O-N 2.91Å; N340-C342 PolarHBondContact O-N 3.11Å; N340-C343 PolarHBondContact O-N 3.3Å
341	S	87.2	Confident	85.1	Confident	5 Å²	5	37.2 Å²	37.2	4%	0.035	19%	0.187	C	C	.	.	H	α-helix	trans	-66.9	-22.8	179.7	-60.9	0	0	0	0	113.1	N69 V100 S338 L339	N69-S341 PolarHBondContact ND2-O 2.8Å; N69-S341 VanDerWaalsContact ND2-O 3.14Å; V100-S341 WeakPolarHBondContact CG1-OG 3.41Å; S338-S341 PolarHBondContact O-N 3.45Å; L339-S341 VanDerWaalsContact C-N 3.25Å; L339-S341 PolarHBondContact O-N 3.47Å
342	C	89.5	Confident	84.6	Confident	11 Å²	11	37.5 Å²	37.5	7%	0.074	19%	0.189	C	C	.	.	H	α-helix	trans	-79.7	-30.5	177.2	-59.9	0	0	0	0	112.3	T61 V64 L339 N340 P345 W346	T61-C342 PolarHBondContact O-SG 2.87Å; T61-C342 VanDerWaalsContact O-SG 3.4Å; V64-C342 HydrophobicContact CG1-CB 3.77Å; L339-C342 VanDerWaalsContact O-CB 3.31Å; L339-C342 WeakPolarHBondContact O-CB 3.25Å; L339-C342 PolarHBondContact O-N 3.19Å; N340-C342 PolarHBondContact O-N 3.11Å; C342-P345 WeakPolarHBondContact O-CD 3.38Å; C342-W346 PolarHBondContact O-NE1 2.92Å
343	C	89.3	Confident	83.8	Confident	41 Å²	41	34.3 Å²	34.3	28%	0.277	18%	0.181	S	C	.	.	H	α-helix	trans	-69.3	-33	-176.2	-65.1	0	0	0	0	113.2	L339 N340 W346 I347	L339-C343 PolarHBondContact O-N 3.39Å; L339-C343 PolarHBondContact O-SG 3.36Å; N340-C343 PolarHBondContact O-N 3.3Å; C343-W346 PolarHBondContact O-N 2.87Å; C343-I347 HydrophobicContact CB-CD1 4.17Å; C343-I347 WeakPolarHBondContact O-CG1 2.81Å; C343-I347 PolarHBondContact O-N 2.72Å; C343-I347 VanDerWaalsContact O-N 3.09Å
344	N	86.5	Confident	83	Confident	0 Å²	0	37.3 Å²	37.3	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-58.2	-50.3	-170	-69	-15.2	0	0	0	114.1	D97 W346 I347 Y348	D97-N344 PolarHBondContact OD2-ND2 3.39Å; N344-W346 VanDerWaalsContact C-N 3.32Å; N344-W346 PolarHBondContact O-N 2.88Å; N344-I347 PolarHBondContact O-N 3.41Å; N344-I347 VanDerWaalsContact O-N 3.14Å; N344-Y348 HydrophobicContact CB-CE2 3.87Å; N344-Y348 WeakPolarHBondContact O-CD2 3.26Å; N344-Y348 WeakPolarHBondContact O-CE2 3.31Å; N344-Y348 PolarHBondContact O-N 3.41Å
345	P	85.1	Confident	82.1	Confident	3 Å²	3	35.9 Å²	35.9	2%	0.019	18%	0.182	C	C	.	.	H	α-helix	trans	-53.1	-44.9	175.4	-28.7	36.3	0	0	0	113.8	V72 C342 I347 Y348 M349	V72-P345 HydrophobicContact CG2-CB 3.94Å; V72-P345 HydrophobicContact CG2-CG 4.35Å; C342-P345 WeakPolarHBondContact O-CD 3.38Å; P345-I347 PolarHBondContact O-N 3.43Å; P345-Y348 PolarHBondContact O-N 2.87Å; P345-M349 WeakPolarHBondContact O-CG 2.97Å; P345-M349 PolarHBondContact O-N 2.98Å
346	W	84.5	Confident	81.2	Confident	142 Å²	142	38.8 Å²	38.8	54%	0.538	20%	0.197	S	C	.	.	H	α-helix	trans	-62.3	-44.6	178.4	-56	103.5	0	0	0	111.3	C342 C343 N344 Y348 M349 F350	C342-W346 PolarHBondContact O-NE1 2.92Å; C343-W346 PolarHBondContact O-N 2.87Å; N344-W346 VanDerWaalsContact C-N 3.32Å; N344-W346 PolarHBondContact O-N 2.88Å; W346-Y348 VanDerWaalsContact C-N 3.32Å; W346-Y348 PolarHBondContact O-N 3.44Å; W346-M349 HydrophobicContact CB-CE 4.47Å; W346-M349 HydrophobicContact CD2-CE 3.74Å; W346-M349 HydrophobicContact CE3-CE 3.29Å; W346-M349 HydrophobicContact CG-CE 4.27Å; W346-M349 HydrophobicContact CZ3-CE 3.74Å; W346-M349 PolarHBondContact O-N 3.39Å; W346-F350 HydrophobicContact CB-CE2 4.41Å; W346-F350 WeakPolarHBondContact O-CD2 3.16Å; W346-F350 PolarHBondContact O-N 2.89Å
347	I	87.2	Confident	80.2	Confident	15 Å²	15	41.5 Å²	41.5	8%	0.077	21%	0.208	C	C	.	.	H	α-helix	trans	-60.8	-42.7	177.7	-61.4	163.7	0	0	0	110.6	M292 V295 I296 A299 C343 N344 P345 M349 F350 F351	M292-I347 HydrophobicContact CG-CG2 4.04Å; V295-I347 HydrophobicContact CB-CG2 4.35Å; V295-I347 HydrophobicContact CG1-CD1 3.98Å; V295-I347 HydrophobicContact CG1-CG1 3.99Å; V295-I347 HydrophobicContact CG1-CG2 4.14Å; I296-I347 HydrophobicContact CB-CD1 4.44Å; I296-I347 HydrophobicContact CD1-CG2 4.29Å; I296-I347 HydrophobicContact CG1-CB 4.24Å; I296-I347 HydrophobicContact CG1-CD1 3.86Å; I296-I347 HydrophobicContact CG1-CG2 3.68Å; A299-I347 HydrophobicContact CB-CD1 4.48Å; C343-I347 HydrophobicContact CB-CD1 4.17Å; C343-I347 WeakPolarHBondContact O-CG1 2.81Å; C343-I347 PolarHBondContact O-N 2.72Å; C343-I347 VanDerWaalsContact O-N 3.09Å; N344-I347 PolarHBondContact O-N 3.41Å; N344-I347 VanDerWaalsContact O-N 3.14Å; P345-I347 PolarHBondContact O-N 3.43Å; I347-M349 PolarHBondContact O-N 2.66Å; I347-F350 PolarHBondContact O-N 3.03Å; I347-F351 HydrophobicContact CG2-CD2 3.83Å; I347-F351 HydrophobicContact CG2-CE2 4.26Å; I347-F351 WeakPolarHBondContact O-CB 3.06Å; I347-F351 WeakPolarHBondContact O-CD2 3.09Å; I347-F351 PolarHBondContact O-N 3.43Å
348	Y	82.8	Confident	79.4	Confident	1 Å²	1	43 Å²	43	0%	0.004	22%	0.216	C	C	.	.	H	α-helix	trans	-64.4	-40.3	176.1	-58.8	-47.8	0	0	0	112.6	V72 I90 L93 M292 I296 N344 P345 W346 F351 S352	V72-Y348 HydrophobicContact CG1-CD2 4.09Å; V72-Y348 HydrophobicContact CG2-CD2 4.03Å; I90-Y348 HydrophobicContact CB-CE1 4.48Å; I90-Y348 HydrophobicContact CD1-CD1 4.05Å; I90-Y348 HydrophobicContact CD1-CE1 4.21Å; I90-Y348 HydrophobicContact CG1-CD1 4.15Å; I90-Y348 HydrophobicContact CG1-CE1 3.81Å; I90-Y348 HydrophobicContact CG2-CD1 4.18Å; I90-Y348 HydrophobicContact CG2-CD2 3.98Å; I90-Y348 HydrophobicContact CG2-CE1 4.04Å; I90-Y348 HydrophobicContact CG2-CE2 3.84Å; I90-Y348 HydrophobicContact CG2-CG 4.17Å; L93-Y348 WeakPolarHBondContact CD2-OH 3.46Å; L93-Y348 WeakPolarHBondContact CG-OH 3.27Å; M292-Y348 HydrophobicContact CE-CD1 4.08Å; M292-Y348 HydrophobicContact CE-CE1 4.01Å; M292-Y348 HydrophobicContact SD-CD1 3.87Å; M292-Y348 HydrophobicContact SD-CE1 4.36Å; I296-Y348 HydrophobicContact CD1-CD1 4.43Å; I296-Y348 HydrophobicContact CD1-CE1 3.56Å; N344-Y348 HydrophobicContact CB-CE2 3.87Å; N344-Y348 WeakPolarHBondContact O-CD2 3.26Å; N344-Y348 WeakPolarHBondContact O-CE2 3.31Å; N344-Y348 PolarHBondContact O-N 3.41Å; P345-Y348 PolarHBondContact O-N 2.87Å; W346-Y348 VanDerWaalsContact C-N 3.32Å; W346-Y348 PolarHBondContact O-N 3.44Å; Y348-F351 PolarHBondContact O-N 3.06Å; Y348-S352 VanDerWaalsContact O-CA 3.32Å; Y348-S352 WeakPolarHBondContact O-CA 3.35Å; Y348-S352 WeakPolarHBondContact O-CB 3.32Å; Y348-S352 PolarHBondContact O-N 2.85Å
349	M	78.2	Confident	78.6	Confident	42 Å²	42	43.4 Å²	43.4	21%	0.207	22%	0.219	C	C	.	.	H	α-helix	trans	-61.7	-44.7	177.8	-73.7	-171.9	-68	0	0	111.6	P345 W346 I347 L356	P345-M349 WeakPolarHBondContact O-CG 2.97Å; P345-M349 PolarHBondContact O-N 2.98Å; W346-M349 HydrophobicContact CB-CE 4.47Å; W346-M349 HydrophobicContact CD2-CE 3.74Å; W346-M349 HydrophobicContact CE3-CE 3.29Å; W346-M349 HydrophobicContact CG-CE 4.27Å; W346-M349 HydrophobicContact CZ3-CE 3.74Å; W346-M349 PolarHBondContact O-N 3.39Å; I347-M349 PolarHBondContact O-N 2.66Å; M349-L356 HydrophobicContact CB-CB 4.45Å; M349-L356 HydrophobicContact CB-CD1 4.24Å
350	F	80.7	Confident	77.8	Confident	158 Å²	158	43.4 Å²	43.4	69%	0.693	22%	0.221	S	C	*	.	H	α-helix	trans	-67.8	-44.3	177.2	-74	-64.2	0	0	0	112.8	W346 I347	W346-F350 HydrophobicContact CB-CE2 4.41Å; W346-F350 WeakPolarHBondContact O-CD2 3.16Å; W346-F350 PolarHBondContact O-N 2.89Å; I347-F350 PolarHBondContact O-N 3.03Å
351	F	78.1	Confident	76.6	Confident	51 Å²	51	46.2 Å²	46.2	22%	0.224	23%	0.234	C	C	.	.	H	α-helix	trans	-86.8	-14.3	-175.7	-80	-89	0	0	0	114	R288 K291 M292 V295 I347 Y348	R288-F351 PolarHBondContact NE-O 2.81Å; R288-F351 PolarHBondContact NH2-O 3.39Å; K291-F351 HydrophobicContact CB-CE1 3.7Å; K291-F351 HydrophobicContact CB-CZ 4.39Å; M292-F351 HydrophobicContact CB-CB 3.68Å; M292-F351 HydrophobicContact CB-CD1 3.71Å; M292-F351 HydrophobicContact CB-CD2 4.22Å; M292-F351 HydrophobicContact CB-CE1 4.41Å; M292-F351 HydrophobicContact CB-CG 3.59Å; M292-F351 HydrophobicContact CG-CB 3.49Å; M292-F351 VanDerWaalsContact CG-CB 3.49Å; M292-F351 HydrophobicContact CG-CD1 4.39Å; M292-F351 HydrophobicContact CG-CD2 4.14Å; M292-F351 HydrophobicContact CG-CG 3.76Å; M292-F351 HydrophobicContact SD-CB 3.77Å; V295-F351 HydrophobicContact CB-CE2 4.25Å; V295-F351 HydrophobicContact CG1-CE2 4.5Å; V295-F351 HydrophobicContact CG2-CE2 3.89Å; V295-F351 HydrophobicContact CG2-CZ 3.81Å; I347-F351 HydrophobicContact CG2-CD2 3.83Å; I347-F351 HydrophobicContact CG2-CE2 4.26Å; I347-F351 WeakPolarHBondContact O-CB 3.06Å; I347-F351 WeakPolarHBondContact O-CD2 3.09Å; I347-F351 PolarHBondContact O-N 3.43Å; Y348-F351 PolarHBondContact O-N 3.06Å
352	S	69.4	Low	75.6	Confident	17 Å²	17	46.7 Å²	46.7	12%	0.119	24%	0.238	C	C	.	.			trans	-128.2	75.9	179.3	-56.7	0	0	0	0	109.4	Y348 H354 L355 L356	Y348-S352 VanDerWaalsContact O-CA 3.32Å; Y348-S352 WeakPolarHBondContact O-CA 3.35Å; Y348-S352 WeakPolarHBondContact O-CB 3.32Å; Y348-S352 PolarHBondContact O-N 2.85Å; S352-H354 PolarHBondContact O-N 3.06Å; S352-L355 WeakPolarHBondContact O-CA 3.09Å; S352-L355 WeakPolarHBondContact O-CB 3.27Å; S352-L355 PolarHBondContact O-N 2.91Å; S352-L356 PolarHBondContact O-N 2.93Å
353	G	66	Low	74.7	Confident	36 Å²	36	51.3 Å²	51.3	37%	0.371	26%	0.257	S	S	.	.	H	α-helix	trans	-53.1	-26.2	-178.4	0	0	0	0	0	114.7	L356 Q357	G353-L356 PolarHBondContact O-N 2.89Å; G353-Q357 PolarHBondContact O-N 3.26Å; G353-Q357 VanDerWaalsContact O-N 3.14Å
354	H	70.5	Confident	73.3	Confident	75 Å²	75	53.8 Å²	53.8	35%	0.347	27%	0.272	S	S	.	.	H	α-helix	trans	-67.7	-37	172.3	84.5	-82.5	0	0	0	112.9	H87 S352 L356 Q357 D358	H87-H354 AromaticContact CE1-CE1 3.99Å; H87-H354 AromaticContact CE1-NE2 3.47Å; H87-H354 PolarHBondContact CE1-NE2 3.48Å; H87-H354 AromaticContact NE2-CE1 3.49Å; H87-H354 PolarHBondContact NE2-CE1 2.81Å; H87-H354 AromaticContact NE2-NE2 3.41Å; H87-H354 PolarHBondContact NE2-NE2 3.08Å; S352-H354 PolarHBondContact O-N 3.06Å; H354-L356 VanDerWaalsContact C-N 3.33Å; H354-Q357 PolarHBondContact O-N 3.43Å; H354-D358 IonicContact CD2-OD2 3.65Å; H354-D358 WeakPolarHBondContact O-CB 3.16Å; H354-D358 VanDerWaalsContact O-CG 3.29Å; H354-D358 PolarHBondContact O-N 2.87Å
355	L	64.7	Low	72.1	Confident	6 Å²	6	58.9 Å²	58.9	3%	0.031	31%	0.307	C	S	.	.	H	α-helix	trans	-69.3	-34.4	176.1	-62.4	-179.3	0	0	0	111.1	L76 I90 S352 Q357 D358 C359	L76-L355 HydrophobicContact CD2-CD1 4.34Å; L76-L355 HydrophobicContact CD2-CD2 3.68Å; L76-L355 HydrophobicContact CG-CD2 4.38Å; I90-L355 HydrophobicContact CD1-CD1 4.41Å; S352-L355 WeakPolarHBondContact O-CA 3.09Å; S352-L355 WeakPolarHBondContact O-CB 3.27Å; S352-L355 PolarHBondContact O-N 2.91Å; L355-Q357 VanDerWaalsContact C-N 3.35Å; L355-D358 PolarHBondContact O-N 3.34Å; L355-C359 WeakPolarHBondContact O-CB 3.09Å; L355-C359 PolarHBondContact O-N 3.34Å
356	L	68.1	Low	70.7	Confident	78 Å²	78	61 Å²	61	41%	0.408	32%	0.321	S	S	.	.	H	α-helix	trans	-61.9	-46.3	172.3	-174.4	152.7	0	0	0	110.1	M349 S352 G353 H354 D358 C359 V360	M349-L356 HydrophobicContact CB-CB 4.45Å; M349-L356 HydrophobicContact CB-CD1 4.24Å; S352-L356 PolarHBondContact O-N 2.93Å; G353-L356 PolarHBondContact O-N 2.89Å; H354-L356 VanDerWaalsContact C-N 3.33Å; L356-D358 PolarHBondContact O-N 2.88Å; L356-C359 PolarHBondContact O-N 2.69Å; L356-V360 HydrophobicContact CD2-CG2 4.06Å; L356-V360 WeakPolarHBondContact O-CB 3.46Å; L356-V360 VanDerWaalsContact O-CG2 3.25Å; L356-V360 WeakPolarHBondContact O-CG2 3.28Å; L356-V360 PolarHBondContact O-N 2.96Å
357	Q	68.2	Low	69.5	Low	116 Å²	116	58.8 Å²	58.8	54%	0.542	32%	0.317	S	S	.	.	H	α-helix	trans	-61.6	-42.8	176.4	-175.9	175.7	3.9	0	0	112.3	G353 H354 L355 Q361	G353-Q357 PolarHBondContact O-N 3.26Å; G353-Q357 VanDerWaalsContact O-N 3.14Å; H354-Q357 PolarHBondContact O-N 3.43Å; L355-Q357 VanDerWaalsContact C-N 3.35Å; Q357-Q361 VanDerWaalsContact CG-NE2 3.31Å; Q357-Q361 WeakPolarHBondContact O-CB 3.27Å; Q357-Q361 VanDerWaalsContact O-CG 3.26Å; Q357-Q361 WeakPolarHBondContact O-CG 3.33Å; Q357-Q361 PolarHBondContact O-N 3.06Å
358	D	69.5	Low	68	Low	32 Å²	32	63.4 Å²	63.4	17%	0.171	34%	0.341	C	S	.	.	H	α-helix	trans	-70	-34.1	178.4	-69.3	-15.6	0	0	0	112.3	A75 T79 H354 L355 L356 S362	A75-D358 HydrophobicContact CB-CB 4.17Å; T79-D358 PolarHBondContact OG1-OD2 3.48Å; H354-D358 IonicContact CD2-OD2 3.65Å; H354-D358 WeakPolarHBondContact O-CB 3.16Å; H354-D358 VanDerWaalsContact O-CG 3.29Å; H354-D358 PolarHBondContact O-N 2.87Å; L355-D358 PolarHBondContact O-N 3.34Å; L356-D358 PolarHBondContact O-N 2.88Å; D358-S362 WeakPolarHBondContact O-CB 3.44Å; D358-S362 PolarHBondContact O-N 2.9Å; D358-S362 VanDerWaalsContact O-N 3.09Å; D358-S362 PolarHBondContact O-OG 3.03Å
359	C	68.9	Low	66.6	Low	14 Å²	14	69.9 Å²	69.9	10%	0.095	37%	0.374	C	S	.	.	H	α-helix	trans	-68.4	-46.5	174.1	-172.4	0	0	0	0	110.9	A75 L355 L356 Q361 S362 F363	A75-C359 HydrophobicContact CB-CB 4.39Å; L355-C359 WeakPolarHBondContact O-CB 3.09Å; L355-C359 PolarHBondContact O-N 3.34Å; L356-C359 PolarHBondContact O-N 2.69Å; C359-Q361 VanDerWaalsContact C-N 3.34Å; C359-Q361 PolarHBondContact O-N 3.42Å; C359-S362 WeakPolarHBondContact O-CA 3.4Å; C359-S362 VanDerWaalsContact O-CB 3.22Å; C359-S362 WeakPolarHBondContact O-CB 3.37Å; C359-S362 PolarHBondContact O-N 3.4Å; C359-F363 WeakPolarHBondContact O-CD2 3.44Å
360	V	69.5	Low	65.4	Low	67 Å²	67	73.1 Å²	73.1	41%	0.406	39%	0.386	S	S	.	.	H	α-helix	trans	-61.1	-43.7	175.2	172.5	0	0	0	0	110.8	L356 S362 F363 C366	L356-V360 HydrophobicContact CD2-CG2 4.06Å; L356-V360 WeakPolarHBondContact O-CB 3.46Å; L356-V360 VanDerWaalsContact O-CG2 3.25Å; L356-V360 WeakPolarHBondContact O-CG2 3.28Å; L356-V360 PolarHBondContact O-N 2.96Å; V360-S362 PolarHBondContact O-N 3.39Å; V360-F363 PolarHBondContact O-N 3.3Å; V360-C366 HydrophobicContact CG1-CB 4.27Å; V360-C366 VanDerWaalsContact O-CB 3.24Å; V360-C366 WeakPolarHBondContact O-CB 3.45Å
361	Q	65.7	Low	64.3	Low	60 Å²	60	72.2 Å²	72.2	28%	0.28	38%	0.384	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66.6	-14.6	174.8	-73.5	178.7	38.4	0	0	113.7	Q357 C359 Q367	Q357-Q361 VanDerWaalsContact CG-NE2 3.31Å; Q357-Q361 WeakPolarHBondContact O-CB 3.27Å; Q357-Q361 VanDerWaalsContact O-CG 3.26Å; Q357-Q361 WeakPolarHBondContact O-CG 3.33Å; Q357-Q361 PolarHBondContact O-N 3.06Å; C359-Q361 VanDerWaalsContact C-N 3.34Å; C359-Q361 PolarHBondContact O-N 3.42Å; Q361-Q367 WeakPolarHBondContact O-CG 3.17Å; Q361-Q367 PolarHBondContact O-NE2 2.97Å
362	S	66.2	Low	63.2	Low	16 Å²	16	76.4 Å²	76.4	11%	0.112	40%	0.403	C	S	.	.	T	Hydrogen-bonded Turn	trans	-82	-17.9	177.8	-71.6	0	0	0	0	113.7	R78 D358 C359 V360	R78-S362 PolarHBondContact NH1-O 2.95Å; R78-S362 PolarHBondContact NH1-OG 3.49Å; D358-S362 WeakPolarHBondContact O-CB 3.44Å; D358-S362 PolarHBondContact O-N 2.9Å; D358-S362 VanDerWaalsContact O-N 3.09Å; D358-S362 PolarHBondContact O-OG 3.03Å; C359-S362 WeakPolarHBondContact O-CA 3.4Å; C359-S362 VanDerWaalsContact O-CB 3.22Å; C359-S362 WeakPolarHBondContact O-CB 3.37Å; C359-S362 PolarHBondContact O-N 3.4Å; V360-S362 PolarHBondContact O-N 3.39Å
363	F	68.8	Low	62.4	Low	108 Å²	108	81.8 Å²	81.8	47%	0.474	42%	0.424	S	S	.	.	S	Bend	trans	-78.7	129.6	174.4	-70.7	-79.2	0	0	0	110.5	C359 V360 C365 C366 Q367	C359-F363 WeakPolarHBondContact O-CD2 3.44Å; V360-F363 PolarHBondContact O-N 3.3Å; F363-C365 PolarHBondContact O-N 2.92Å; F363-C365 VanDerWaalsContact O-N 3.14Å; F363-C366 PolarHBondContact O-N 3.41Å; F363-Q367 PolarHBondContact O-N 3Å
364	P	59.9	Low	61.9	Low	93 Å²	93	84.3 Å²	84.3	60%	0.604	43%	0.429	S	S	*	.	H	α-helix	trans	-53.7	-36.2	-177.2	-25.8	32.4	0	0	0	113.9	C366 Q367	P364-C366 PolarHBondContact O-N 3.39Å; P364-Q367 PolarHBondContact O-N 2.87Å
365	C	61.3	Low	61	Low	106 Å²	106	87.9 Å²	87.9	72%	0.716	44%	0.443	S	S	*	.	H	α-helix	trans	-61.4	-28.2	178.2	-63.8	0	0	0	0	113.6	F363	F363-C365 PolarHBondContact O-N 2.92Å; F363-C365 VanDerWaalsContact O-N 3.14Å
366	C	57.3	Low	60.7	Low	47 Å²	47	92.9 Å²	92.9	32%	0.318	47%	0.467	S	S	.	.	H	α-helix	trans	-91.2	-19	-179	-65	0	0	0	0	113.2	V360 F363 P364 M369 K370	V360-C366 HydrophobicContact CG1-CB 4.27Å; V360-C366 VanDerWaalsContact O-CB 3.24Å; V360-C366 WeakPolarHBondContact O-CB 3.45Å; F363-C366 PolarHBondContact O-N 3.41Å; P364-C366 PolarHBondContact O-N 3.39Å; C366-M369 PolarHBondContact O-N 3.3Å; C366-K370 PolarHBondContact O-N 3.43Å
367	Q	58.5	Low	60.1	Low	96 Å²	96	93.1 Å²	93.1	45%	0.449	47%	0.468	S	S	.	.	H	α-helix	trans	-66.5	-41.6	173.1	-67.4	-173.2	-21.1	0	0	110.9	Q361 F363 P364 M369 K370 E371	Q361-Q367 WeakPolarHBondContact O-CG 3.17Å; Q361-Q367 PolarHBondContact O-NE2 2.97Å; F363-Q367 PolarHBondContact O-N 3Å; P364-Q367 PolarHBondContact O-N 2.87Å; Q367-M369 VanDerWaalsContact C-N 3.27Å; Q367-M369 PolarHBondContact O-N 3.31Å; Q367-K370 PolarHBondContact O-N 2.96Å; Q367-E371 PolarHBondContact O-N 3.42Å; Q367-E371 VanDerWaalsContact O-N 3.12Å
368	N	55	Low	59.6	Low	112 Å²	112	92 Å²	92	60%	0.599	47%	0.47	S	S	*	.	H	α-helix	trans	-60.2	-34.8	174.9	-74.8	-13.3	0	0	0	113	K372	N368-K372 WeakPolarHBondContact O-CB 3.38Å; N368-K372 PolarHBondContact O-N 3.08Å; N368-K372 VanDerWaalsContact O-N 3.07Å
369	M	54.4	Low	59.1	Low	138 Å²	138	94.4 Å²	94.4	68%	0.68	48%	0.482	S	S	*	.	H	α-helix	trans	-69.6	-37.3	178.6	-70.6	-83.4	-79.8	0	0	112.1	C366 Q367 K372 F373	C366-M369 PolarHBondContact O-N 3.3Å; Q367-M369 VanDerWaalsContact C-N 3.27Å; Q367-M369 PolarHBondContact O-N 3.31Å; M369-K372 PolarHBondContact O-N 2.79Å; M369-F373 WeakPolarHBondContact O-CB 3.4Å; M369-F373 PolarHBondContact O-N 2.9Å
370	K	53.7	Low	58.6	Low	109 Å²	109	96 Å²	96	47%	0.474	49%	0.494	S	S	.	.	H	α-helix	trans	-73.5	-37.6	179	-169	178.8	-178.1	-176.7	0	112.1	C366 Q367 K372 F373 N374	C366-K370 PolarHBondContact O-N 3.43Å; Q367-K370 PolarHBondContact O-N 2.96Å; K370-K372 VanDerWaalsContact C-N 3.32Å; K370-F373 PolarHBondContact O-N 3.31Å; K370-N374 WeakPolarHBondContact O-CB 3.47Å; K370-N374 PolarHBondContact O-N 3.35Å
371	E	56.7	Low	57.9	Low	140 Å²	140	98.4 Å²	98.4	65%	0.654	50%	0.502	S	S	*	.	H	α-helix	trans	-64.2	-39.8	172.3	-73.3	-173.4	166.2	0	0	111.4	Q367 K375	Q367-E371 PolarHBondContact O-N 3.42Å; Q367-E371 VanDerWaalsContact O-N 3.12Å; E371-K375 VanDerWaalsContact O-CB 3.25Å; E371-K375 WeakPolarHBondContact O-CB 3.46Å; E371-K375 PolarHBondContact O-N 2.87Å
372	K	54.3	Low	57.6	Low	139 Å²	139	98.6 Å²	98.6	60%	0.604	51%	0.51	S	S	*	.	H	α-helix	trans	-65.7	-43.1	176.5	-149.1	174.4	-174.5	-175.5	0	112.2	N368 M369 K370 K375 E376	N368-K372 WeakPolarHBondContact O-CB 3.38Å; N368-K372 PolarHBondContact O-N 3.08Å; N368-K372 VanDerWaalsContact O-N 3.07Å; M369-K372 PolarHBondContact O-N 2.79Å; K370-K372 VanDerWaalsContact C-N 3.32Å; K372-K375 PolarHBondContact O-N 3.32Å; K372-E376 WeakPolarHBondContact O-CG 3.37Å; K372-E376 PolarHBondContact O-N 3.43Å
373	F	53	Low	57.1	Low	130 Å²	130	105.8 Å²	105.8	57%	0.57	54%	0.535	S	S	*	.	H	α-helix	trans	-69.7	-41.6	178.9	-148.7	-91.3	0	0	0	112.7	M369 K370 K375 E376 D377	M369-F373 WeakPolarHBondContact O-CB 3.4Å; M369-F373 PolarHBondContact O-N 2.9Å; K370-F373 PolarHBondContact O-N 3.31Å; F373-K375 VanDerWaalsContact C-N 3.29Å; F373-K375 PolarHBondContact O-N 2.94Å; F373-E376 PolarHBondContact O-N 3.34Å; F373-D377 PolarHBondContact O-N 3.43Å
374	N	54.9	Low	56.5	Low	89 Å²	89	108.9 Å²	108.9	48%	0.476	54%	0.543	S	S	.	.	H	α-helix	trans	-65.1	-34	174.6	-78.2	-19.2	0	0	0	111.9	K370 T378	K370-N374 WeakPolarHBondContact O-CB 3.47Å; K370-N374 PolarHBondContact O-N 3.35Å; N374-T378 WeakPolarHBondContact O-CB 3.31Å; N374-T378 PolarHBondContact O-N 2.84Å; N374-T378 PolarHBondContact O-OG1 3.05Å
375	K	53.6	Low	56.3	Low	149 Å²	149	111 Å²	111	65%	0.648	55%	0.545	S	S	*	.	H	α-helix	trans	-68.7	-41.6	175.3	-167.1	169.3	-178.2	172.2	0	111.4	E371 K372 F373 T378 D379	E371-K375 VanDerWaalsContact O-CB 3.25Å; E371-K375 WeakPolarHBondContact O-CB 3.46Å; E371-K375 PolarHBondContact O-N 2.87Å; K372-K375 PolarHBondContact O-N 3.32Å; F373-K375 VanDerWaalsContact C-N 3.29Å; F373-K375 PolarHBondContact O-N 2.94Å; K375-T378 PolarHBondContact O-N 2.81Å; K375-D379 WeakPolarHBondContact O-CB 3.23Å; K375-D379 PolarHBondContact O-N 3.04Å
376	E	56.4	Low	56.2	Low	111 Å²	111	109.8 Å²	109.8	52%	0.519	54%	0.535	S	S	.	.	H	α-helix	trans	-65.7	-39.5	175	-74.7	171.1	176	0	0	113	K372 F373 D379 S380	K372-E376 WeakPolarHBondContact O-CG 3.37Å; K372-E376 PolarHBondContact O-N 3.43Å; F373-E376 PolarHBondContact O-N 3.34Å; E376-D379 PolarHBondContact O-N 3.04Å; E376-S380 WeakPolarHBondContact O-CB 3.28Å; E376-S380 PolarHBondContact O-N 3.05Å
377	D	56.6	Low	56	Low	83 Å²	83	114.8 Å²	114.8	44%	0.444	55%	0.551	S	S	.	*	H	α-helix	trans	-68	-37	175.1	-85.5	-27.4	0	0	0	112.3	F373 S380 M381	F373-D377 PolarHBondContact O-N 3.43Å; D377-S380 PolarHBondContact O-N 3.35Å; D377-M381 WeakPolarHBondContact O-CB 3.35Å; D377-M381 WeakPolarHBondContact O-CG 3.38Å; D377-M381 PolarHBondContact O-N 3.47Å
378	T	58.4	Low	55.7	Low	94 Å²	94	119.6 Å²	119.6	58%	0.577	57%	0.567	S	S	*	*	H	α-helix	trans	-67.8	-41.3	176.3	-51.7	0	0	0	0	111	N374 K375 S382	N374-T378 WeakPolarHBondContact O-CB 3.31Å; N374-T378 PolarHBondContact O-N 2.84Å; N374-T378 PolarHBondContact O-OG1 3.05Å; K375-T378 PolarHBondContact O-N 2.81Å; T378-S382 VanDerWaalsContact O-CB 3.29Å; T378-S382 WeakPolarHBondContact O-CB 3.34Å; T378-S382 PolarHBondContact O-N 2.7Å
379	D	58.6	Low	55.7	Low	81 Å²	81	118.6 Å²	118.6	43%	0.433	57%	0.569	S	S	.	*	H	α-helix	trans	-69.8	-33.8	176.1	-74.5	-18.3	0	0	0	112.4	K375 E376 R383	K375-D379 WeakPolarHBondContact O-CB 3.23Å; K375-D379 PolarHBondContact O-N 3.04Å; E376-D379 PolarHBondContact O-N 3.04Å; D379-R383 WeakPolarHBondContact O-CB 3.33Å; D379-R383 PolarHBondContact O-N 3.07Å
380	S	57.1	Low	55.8	Low	48 Å²	48	118.4 Å²	118.4	34%	0.336	57%	0.57	S	S	.	*	H	α-helix	trans	-67.3	-44.2	173.9	169	0	0	0	0	112.4	E376 D377 R383 R384	E376-S380 WeakPolarHBondContact O-CB 3.28Å; E376-S380 PolarHBondContact O-N 3.05Å; D377-S380 PolarHBondContact O-N 3.35Å; S380-R383 PolarHBondContact O-N 3.41Å; S380-R384 PolarHBondContact O-N 2.75Å
381	M	56.6	Low	55.6	Low	117 Å²	117	120.1 Å²	120.1	58%	0.576	58%	0.584	S	S	*	*	H	α-helix	trans	-68.2	-40.1	175.7	-76	-133	71.8	0	0	112.3	D377 R384 Q385	D377-M381 WeakPolarHBondContact O-CB 3.35Å; D377-M381 WeakPolarHBondContact O-CG 3.38Å; D377-M381 PolarHBondContact O-N 3.47Å; M381-R384 PolarHBondContact O-N 3.02Å; M381-Q385 PolarHBondContact O-N 2.94Å
382	S	57.6	Low	55	Low	65 Å²	65	124.3 Å²	124.3	46%	0.455	59%	0.594	S	S	.	*	H	α-helix	trans	-58.9	-46.8	173.1	172.5	0	0	0	0	111.3	T378 R384 Q385 T386	T378-S382 VanDerWaalsContact O-CB 3.29Å; T378-S382 WeakPolarHBondContact O-CB 3.34Å; T378-S382 PolarHBondContact O-N 2.7Å; S382-R384 PolarHBondContact O-N 2.92Å; S382-Q385 PolarHBondContact O-N 3.49Å; S382-T386 PolarHBondContact O-N 3.38Å; S382-T386 PolarHBondContact O-OG1 3.03Å
383	R	56.9	Low	54.5	Low	167 Å²	167	122.5 Å²	122.5	63%	0.63	60%	0.599	S	S	*	*	H	α-helix	trans	-61.6	-42.4	175.5	-115.1	179	-81.4	-164.6	-6	112.6	D379 S380 T386 F387	D379-R383 WeakPolarHBondContact O-CB 3.33Å; D379-R383 PolarHBondContact O-N 3.07Å; S380-R383 PolarHBondContact O-N 3.41Å; R383-T386 WeakPolarHBondContact CA-OG1 3.35Å; R383-T386 PolarHBondContact O-N 3.49Å; R383-T386 PolarHBondContact O-OG1 3.31Å; R383-F387 WeakPolarHBondContact O-CD2 3.29Å; R383-F387 PolarHBondContact O-N 2.97Å
384	R	56.3	Low	53.9	Low	172 Å²	172	122 Å²	122	65%	0.649	61%	0.609	S	S	*	*	H	α-helix	trans	-64.8	-40.9	176.1	-80.3	-177	-179.8	169.2	2.5	112	S380 M381 S382 F387 Y388	S380-R384 PolarHBondContact O-N 2.75Å; M381-R384 PolarHBondContact O-N 3.02Å; S382-R384 PolarHBondContact O-N 2.92Å; R384-F387 PolarHBondContact O-N 2.89Å; R384-Y388 WeakPolarHBondContact O-CD2 3.36Å; R384-Y388 PolarHBondContact O-N 2.76Å
385	Q	55.8	Low	53.6	Low	139 Å²	139	124.6 Å²	124.6	65%	0.65	63%	0.628	S	S	*	*	H	α-helix	trans	-67.1	-36.8	177.2	-84.7	-177.8	-25.9	0	0	112.9	M381 S382 Y388 S389	M381-Q385 PolarHBondContact O-N 2.94Å; S382-Q385 PolarHBondContact O-N 3.49Å; Q385-Y388 PolarHBondContact O-N 3.26Å; Q385-S389 WeakPolarHBondContact O-CB 3.4Å; Q385-S389 PolarHBondContact O-N 2.96Å
386	T	57.9	Low	53	Low	80 Å²	80	124.9 Å²	124.9	49%	0.491	64%	0.637	S	S	.	*	H	α-helix	trans	-67.8	-37.5	174.5	18.9	0	0	0	0	112.3	S382 R383 S389 N390	S382-T386 PolarHBondContact O-N 3.38Å; S382-T386 PolarHBondContact O-OG1 3.03Å; R383-T386 WeakPolarHBondContact CA-OG1 3.35Å; R383-T386 PolarHBondContact O-N 3.49Å; R383-T386 PolarHBondContact O-OG1 3.31Å; T386-S389 PolarHBondContact O-N 3.35Å; T386-N390 PolarHBondContact O-N 2.86Å; T386-N390 VanDerWaalsContact O-N 3.11Å
387	F	54.9	Low	52.3	Low	152 Å²	152	124.1 Å²	124.1	67%	0.667	64%	0.644	S	S	*	*	H	α-helix	trans	-66.4	-37.2	174	-95.3	-92.1	0	0	0	113.2	R383 R384 N391	R383-F387 WeakPolarHBondContact O-CD2 3.29Å; R383-F387 PolarHBondContact O-N 2.97Å; R384-F387 PolarHBondContact O-N 2.89Å; F387-N391 PolarHBondContact O-N 3.42Å
388	Y	52.1	Low	51.6	Low	197 Å²	197	126.8 Å²	126.8	77%	0.773	66%	0.663	S	S	*	*	H	α-helix	trans	-73.8	-26.2	176.1	-90.3	-79.5	0	0	0	113.4	R384 Q385	R384-Y388 WeakPolarHBondContact O-CD2 3.36Å; R384-Y388 PolarHBondContact O-N 2.76Å; Q385-Y388 PolarHBondContact O-N 3.26Å
389	S	55.1	Low	50.8	Low	91 Å²	91	125.9 Å²	125.9	64%	0.636	67%	0.673	S	S	*	*	H	α-helix	trans	-81.4	-30	177	-164.4	0	0	0	0	113.1	Q385 T386	Q385-S389 WeakPolarHBondContact O-CB 3.4Å; Q385-S389 PolarHBondContact O-N 2.96Å; T386-S389 PolarHBondContact O-N 3.35Å
390	N	54.8	Low	49.9	Very low	133 Å²	133	130 Å²	130	71%	0.711	69%	0.692	S	S	*	*	H	α-helix	trans	-84.6	-15.6	-179.8	-93.7	2.8	0	0	0	114.7	T386 R392	T386-N390 PolarHBondContact O-N 2.86Å; T386-N390 VanDerWaalsContact O-N 3.11Å; N390-R392 VanDerWaalsContact C-N 3.34Å
391	N	50.6	Low	49.1	Very low	145 Å²	145	139 Å²	139	78%	0.775	72%	0.718	S	S	*	*	T	Hydrogen-bonded Turn	trans	-91	10.5	177.3	-97.3	5.1	0	0	0	114.3	F387	F387-N391 PolarHBondContact O-N 3.42Å
392	R	44.3	Very low	48.3	Very low	228 Å²	228	142 Å²	142	86%	0.86	73%	0.728	S	S	*	*			trans	-109.2	67.8	176.5	-150.5	174.3	-167.3	161.7	2.4	110.2	N390	N390-R392 VanDerWaalsContact C-N 3.34Å
393	S	43.6	Very low	47.5	Very low	102 Å²	102	146 Å²	146	71%	0.713	75%	0.745	S	S	*	*			trans	-69.2	146.5	170	-62.7	0	0	0	0	111.1
394	P	40.2	Very low	46.8	Very low	119 Å²	119	143.6 Å²	143.6	77%	0.773	75%	0.753	S	S	*	*			trans	-86	120.9	-167.1	32.7	-31.4	0	0	0	111.5
395	T	48.7	Very low	46.1	Very low	144 Å²	144	141 Å²	141	88%	0.883	76%	0.758	S	S	*	*			trans	-102.5	106.4	163.2	44.2	0	0	0	0	110.1
396	N	41.2	Very low	45.3	Very low	155 Å²	155	144.4 Å²	144.4	83%	0.829	77%	0.771	S	S	*	*			trans	-34	124.2	161.1	-77	-23.6	0	0	0	112.1
397	S	40.7	Very low	44.5	Very low	94 Å²	94	146.2 Å²	146.2	66%	0.657	79%	0.787	S	S	*	*				90.5	128.5	83.8	-173.4	0	0	0	0	113.7
398	T	42.7	Very low	43.8	Very low	140 Å²	140	144.6 Å²	144.6	86%	0.859	80%	0.795	S	S	*	*			trans	93.5	129.1	160.1	70.7	0	0	0	0	120.9
399	G	40.7	Very low	43.1	Very low	75 Å²	75	144.9 Å²	144.9	77%	0.773	80%	0.8	S	S	*	*			trans	101.1	70.9	158.3	0	0	0	0	0	116
400	M	40.5	Very low	42.4	Very low	168 Å²	168	145.1 Å²	145.1	83%	0.828	80%	0.802	S	S	*	*				80.5	100.4	80.8	-152.8	-179.8	86.9	0	0	115.2
401	W	39.9	Very low	41.7	Very low	237 Å²	237	145.2 Å²	145.2	90%	0.898	80%	0.801	S	S	*	*			trans	57.6	126.5	146.8	-62.7	61.8	0	0	0	118.3
402	K	39.7	Very low	41.2	Very low	178 Å²	178	147.7 Å²	147.7	77%	0.774	80%	0.804	S	S	*	*				178	131.1	66.8	-146.4	176	175.6	176.3	0	105.5
403	D	40.6	Very low	41	Very low	151 Å²	151	145.8 Å²	145.8	81%	0.807	80%	0.803	S	S	*	*				-177.1	144.4	95.4	-85.5	-35.7	0	0	0	112.1
404	S	42.6	Very low	41.1	Very low	115 Å²	115	148.8 Å²	148.8	80%	0.804	81%	0.809	S	S	*	*			trans	-62.3	-174.8	-178.3	-87.2	0	0	0	0	117.1
405	P	41.7	Very low	41.3	Very low	118 Å²	118	148.1 Å²	148.1	77%	0.766	81%	0.805	S	S	*	*			cis	-134.6	155.6	-45.6	36.2	-19.7	0	0	0	112.7
406	K	38.6	Very low	41.2	Very low	211 Å²	211	147.7 Å²	147.7	92%	0.917	80%	0.802	S	S	*	*			trans	-125.6	113.6	164.2	-86.2	-174.9	-179.6	175	0	111.9
407	S	41	Very low	41.3	Very low	118 Å²	118	145.4 Å²	145.4	83%	0.825	80%	0.798	S	S	*	*			trans	30.8	109.7	140.1	-167.4	0	0	0	0	118.1
408	S	41.1	Very low	41.8	Very low	118 Å²	118	151.4 Å²	151.4	83%	0.825	83%	0.831	S	S	*	*			trans	-71.3	123.6	172.7	-156.1	0	0	0	0	111.4
409	K	36.8	Very low	41.8	Very low	203 Å²	203	152 Å²	152	88%	0.883	83%	0.829	S	S	*	*			trans	-97.6	130.9	159.3	-79.3	180	176.5	175.8	0	107.7
410	S	40	Very low	41.8	Very low	96 Å²	96	156.1 Å²	156.1	67%	0.671	83%	0.832	S	S	*	*			trans	-146.9	101.7	161.7	-167.7	0	0	0	0	108.2
411	I	41.2	Very low	41.9	Very low	135 Å²	135	155.4 Å²	155.4	69%	0.692	83%	0.833	S	S	*	*				75.8	111.8	101.2	-66.7	166.3	0	0	0	111.7
412	K	40.4	Very low	42	Very low	196 Å²	196	150.6 Å²	150.6	85%	0.852	83%	0.829	S	S	*	*				167.8	153.3	95.3	-127.7	154.4	-163.7	-178.3	0	111.5
413	F	39	Very low	42.1	Very low	189 Å²	189	148.9 Å²	148.9	83%	0.829	83%	0.832	S	S	*	*			trans	-57.5	157.9	178.4	-78.9	-109	0	0	0	114.8
414	I	46.5	Very low	42.2	Very low	164 Å²	164	148.7 Å²	148.7	84%	0.841	83%	0.834	S	S	*	*				-175.6	135.2	122.4	-83.3	145.7	0	0	0	108.7
415	P	43.2	Very low	42.2	Very low	105 Å²	105	151.1 Å²	151.1	68%	0.682	84%	0.836	S	S	*	*			trans	-97.7	158.2	169.4	36.9	-29	0	0	0	112.1
416	V	47.1	Very low	42.3	Very low	136 Å²	136	153.7 Å²	153.7	82%	0.824	84%	0.841	S	S	*	*			trans	169.8	131.3	139.4	152.6	0	0	0	0	112.9
417	S	44.1	Very low	42.6	Very low	106 Å²	106	148.9 Å²	148.9	74%	0.741	84%	0.835	S	S	*	*			trans	45.1	124.1	147.5	-52.3	0	0	0	0	125.2
418	T	50.7	Low	42.7	Very low	221 Å²	221	151.7 Å²	151.7	100%	1.356	84%	0.836	S	S	*	*				-142.7	0	105.9	35.1	0	0	0	0	109.8

Retrieved 418 of 418 residues in 211.6 ms (Link to these results)

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