X5D315_HUMAN Loading...

C-terminal binding protein 1 isoform E

AlphaFold DB , UniProt , Accession X5D315, Species HUMAN (Homo sapiens, Human), Gene CTBP1, Length 50 aa.

						>X5D315_HUMAN|X5D315|CTBP1
MGSSHLLNKGLPLGPERGCGGPDVPHHHSHQGGPGEVQSPPHHRPDWQWF
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	43.4	Very low	54.3	Low	249 Å²	249	140.5 Å²	140.5	100%	1.227	80%	0.8	S	S	*	*				0	130.7	0	-75.4	122.9	81.6	0	0	108
2	G	43	Very low	54.1	Low	75 Å²	75	139.8 Å²	139.8	77%	0.773	80%	0.804	S	S	*	*			trans	-73.7	148.1	-156.2	0	0	0	0	0	116	S4	G2-S4 PolarHBondContact O-N 3.18Å
3	S	47.5	Very low	54.1	Low	125 Å²	125	140.7 Å²	140.7	87%	0.874	80%	0.803	S	S	*	*			trans	-79.6	109.3	166.5	-168.7	0	0	0	0	108.7
4	S	67.8	Low	54.8	Low	87 Å²	87	134.4 Å²	134.4	61%	0.608	79%	0.785	S	S	*	*			trans	-76.1	179.4	162	-55.3	0	0	0	0	109.8	G2	G2-S4 PolarHBondContact O-N 3.18Å
5	H	49.4	Very low	55	Low	166 Å²	166	133.9 Å²	133.9	77%	0.769	79%	0.787	S	S	*	*			trans	98.8	75.2	177.2	-42.1	104	0	0	0	114.4
6	L	65.6	Low	55.1	Low	157 Å²	157	136.8 Å²	136.8	82%	0.822	79%	0.791	S	S	*	*				44.1	121.3	115.5	-57.7	167.4	0	0	0	116.1
7	L	54.3	Low	55.4	Low	166 Å²	166	143.2 Å²	143.2	87%	0.869	80%	0.799	S	S	*	*				164.2	77.3	129.8	-83.7	160.8	0	0	0	109.9
8	N	48.2	Very low	55.5	Low	122 Å²	122	138.8 Å²	138.8	65%	0.652	79%	0.792	S	S	*	*			trans	-143.5	71.7	142.2	-148.4	-87.2	0	0	0	109.6	G10 L11	N8-G10 VanDerWaalsContact C-N 3.29Å; N8-G10 VanDerWaalsContact O-N 3.15Å; N8-G10 PolarHBondContact O-N 3.35Å; N8-L11 PolarHBondContact OD1-N 2.79Å
9	K	56.1	Low	55.7	Low	213 Å²	213	138.5 Å²	138.5	93%	0.926	80%	0.797	S	S	*	*			trans	-66.5	99.2	150.8	-77	-175.5	174.8	-172.4	0	106.2
10	G	60.1	Low	55.7	Low	60 Å²	60	135.5 Å²	135.5	62%	0.619	80%	0.797	S	S	*	*			trans	100.5	89.3	159	0	0	0	0	0	115.8	N8	N8-G10 VanDerWaalsContact C-N 3.29Å; N8-G10 VanDerWaalsContact O-N 3.15Å; N8-G10 PolarHBondContact O-N 3.35Å
11	L	62.3	Low	55.8	Low	126 Å²	126	131.8 Å²	131.8	66%	0.66	79%	0.788	S	S	*	*			trans	-153.8	129.7	135.3	-75.1	-176.6	0	0	0	107.7	N8 L13	N8-L11 PolarHBondContact OD1-N 2.79Å; L11-L13 PolarHBondContact O-N 3.01Å
12	P	51.3	Low	56.3	Low	131 Å²	131	125.5 Å²	125.5	85%	0.851	77%	0.766	S	S	*	*			trans	-72.2	98.7	170.4	29.6	-29.3	0	0	0	107.5	G14	P12-G14 PolarHBondContact O-N 2.82Å
13	L	54.4	Low	57.2	Low	152 Å²	152	129.1 Å²	129.1	80%	0.796	77%	0.767	S	S	*	*			trans	-77.5	74.9	178.9	-72	174.4	0	0	0	110.7	L11	L11-L13 PolarHBondContact O-N 3.01Å
14	G	63.7	Low	57.9	Low	53 Å²	53	127.9 Å²	127.9	55%	0.546	75%	0.754	S	S	.	*			trans	59	157.5	153.7	0	0	0	0	0	118.4	P12 E16	P12-G14 PolarHBondContact O-N 2.82Å; G14-E16 PolarHBondContact O-N 3.12Å
15	P	57.4	Low	57.8	Low	126 Å²	126	128.7 Å²	128.7	82%	0.818	76%	0.757	S	S	*	*			trans	-64.7	106.4	165.9	26.4	-29.1	0	0	0	107.6	R17	P15-R17 PolarHBondContact O-N 2.77Å
16	E	58	Low	58.5	Low	180 Å²	180	128.4 Å²	128.4	84%	0.841	76%	0.756	S	S	*	*			trans	-50.3	118.1	161.1	-64.2	-173.5	95.5	0	0	105.9	G14 G18	G14-E16 PolarHBondContact O-N 3.12Å; E16-G18 PolarHBondContact O-N 2.86Å
17	R	59	Low	58.4	Low	246 Å²	246	128.5 Å²	128.5	93%	0.928	75%	0.752	S	S	*	*			trans	-69.2	75	175	-75	177.4	-82.9	179.2	-4.8	107.1	P15 C19	P15-R17 PolarHBondContact O-N 2.77Å; R17-C19 PolarHBondContact O-N 3.04Å
18	G	57	Low	59	Low	65 Å²	65	128.7 Å²	128.7	67%	0.67	75%	0.748	S	S	*	*			trans	-62.9	124.7	179.7	0	0	0	0	0	109	E16 G20	E16-G18 PolarHBondContact O-N 2.86Å; G18-G20 PolarHBondContact O-N 3.09Å; G18-G20 VanDerWaalsContact O-N 3.17Å
19	C	60.1	Low	60.1	Low	132 Å²	132	127.4 Å²	127.4	89%	0.892	75%	0.749	S	S	*	*	S	Bend	trans	-55.3	116.4	173.5	-56.6	0	0	0	0	109.7	R17 G21	R17-C19 PolarHBondContact O-N 3.04Å; C19-G21 PolarHBondContact O-N 3.42Å
20	G	56.1	Low	60.4	Low	78 Å²	78	125.5 Å²	125.5	80%	0.804	74%	0.743	S	S	*	*			trans	43.1	67.8	155	0	0	0	0	0	116.7	G18	G18-G20 PolarHBondContact O-N 3.09Å; G18-G20 VanDerWaalsContact O-N 3.17Å
21	G	57.7	Low	60.7	Low	58 Å²	58	131.8 Å²	131.8	60%	0.598	76%	0.756	S	S	*	*			trans	-64.1	153.8	150.4	0	0	0	0	0	109.3	C19 D23	C19-G21 PolarHBondContact O-N 3.42Å; G21-D23 PolarHBondContact O-N 2.8Å
22	P	52.8	Low	60.6	Low	117 Å²	117	128.3 Å²	128.3	76%	0.76	75%	0.751	S	S	*	*			trans	-51.2	132.7	-179.5	23.4	-33	0	0	0	108.4	V24	P22-V24 PolarHBondContact O-N 2.91Å; P22-V24 WeakPolarHBondContact O-CG2 3.42Å
23	D	63	Low	61.1	Low	151 Å²	151	124.9 Å²	124.9	81%	0.807	74%	0.739	S	S	*	*			trans	-50.2	95.3	174	-171.8	-100.5	0	0	0	107.3	G21 P25	G21-D23 PolarHBondContact O-N 2.8Å; D23-P25 WeakPolarHBondContact O-CD 3.24Å
24	V	62.4	Low	61.5	Low	99 Å²	99	124 Å²	124	60%	0.6	74%	0.742	S	S	*	*			trans	-69.8	119.7	176.7	173.1	0	0	0	0	102.6	P22 H26	P22-V24 PolarHBondContact O-N 2.91Å; P22-V24 WeakPolarHBondContact O-CG2 3.42Å; V24-H26 PolarHBondContact O-CD2 3.32Å; V24-H26 PolarHBondContact O-N 2.83Å
25	P	64.3	Low	61.5	Low	104 Å²	104	124.3 Å²	124.3	68%	0.675	75%	0.746	S	S	*	*			trans	-57.1	111.7	174.5	21.4	-29.8	0	0	0	106.5	D23 H27	D23-P25 WeakPolarHBondContact O-CD 3.24Å; P25-H27 PolarHBondContact O-N 3.04Å
26	H	64.3	Low	61.7	Low	160 Å²	160	127.5 Å²	127.5	74%	0.741	75%	0.75	S	S	*	*			trans	-67.2	85.8	170.8	-72.8	-84.9	0	0	0	105.7	V24 H28	V24-H26 PolarHBondContact O-CD2 3.32Å; V24-H26 PolarHBondContact O-N 2.83Å; H26-H28 VanDerWaalsContact C-N 3.29Å; H26-H28 PolarHBondContact O-CD2 2.74Å; H26-H28 PolarHBondContact O-N 2.97Å
27	H	64.4	Low	62.1	Low	159 Å²	159	125.5 Å²	125.5	74%	0.736	75%	0.749	S	S	*	*			trans	-67.7	95.4	176.2	-167.5	-81.3	0	0	0	106.5	P25 S29	P25-H27 PolarHBondContact O-N 3.04Å; H27-S29 PolarHBondContact O-N 3.42Å
28	H	67.4	Low	62.3	Low	170 Å²	170	122.1 Å²	122.1	79%	0.787	74%	0.744	S	S	*	*			trans	-61.8	104.9	165.9	-72.6	-85.4	0	0	0	106.5	H26 H30	H26-H28 VanDerWaalsContact C-N 3.29Å; H26-H28 PolarHBondContact O-CD2 2.74Å; H26-H28 PolarHBondContact O-N 2.97Å; H28-H30 PolarHBondContact O-N 3.43Å
29	S	70.1	Confident	62.8	Low	95 Å²	95	123.9 Å²	123.9	66%	0.664	75%	0.746	S	S	*	*			trans	-53.3	117.8	171.1	-61	0	0	0	0	108.1	H27 Q31	H27-S29 PolarHBondContact O-N 3.42Å; S29-Q31 PolarHBondContact O-N 2.8Å
30	H	62.7	Low	63	Low	173 Å²	173	123.3 Å²	123.3	80%	0.801	74%	0.741	S	S	*	*			trans	-54.1	104.3	171.6	-174.1	81	0	0	0	107.8	H28 G32	H28-H30 PolarHBondContact O-N 3.43Å; H30-G32 PolarHBondContact O-N 2.87Å
31	Q	65.7	Low	63.3	Low	193 Å²	193	125.1 Å²	125.1	90%	0.902	74%	0.739	S	S	*	*			trans	-72.5	75.2	166.7	-71.3	-169.5	-8.9	0	0	107.1	S29 G33	S29-Q31 PolarHBondContact O-N 2.8Å; Q31-G33 PolarHBondContact O-N 3.35Å
32	G	61.6	Low	63.5	Low	53 Å²	53	130.5 Å²	130.5	55%	0.546	75%	0.748	S	S	.	*			trans	-61.2	120.1	165.1	0	0	0	0	0	107.7	H30	H30-G32 PolarHBondContact O-N 2.87Å
33	G	62.1	Low	63.9	Low	58 Å²	58	133.1 Å²	133.1	60%	0.598	75%	0.75	S	S	*	*			trans	-68.6	178.2	-156.4	0	0	0	0	0	116.8	Q31 G35	Q31-G33 PolarHBondContact O-N 3.35Å; G33-G35 PolarHBondContact O-N 2.69Å; G33-G35 VanDerWaalsContact O-N 3.09Å
34	P	62.7	Low	63.8	Low	133 Å²	133	136.4 Å²	136.4	86%	0.864	75%	0.751	S	S	*	*			trans	-60.2	117.7	160.9	27.5	-30.2	0	0	0	106.6	E36	P34-E36 PolarHBondContact O-N 3.15Å
35	G	63	Low	63.9	Low	61 Å²	61	135.9 Å²	135.9	63%	0.629	75%	0.749	S	S	*	*			trans	-47.3	140.4	174.6	0	0	0	0	0	109.4	G33 V37	G33-G35 PolarHBondContact O-N 2.69Å; G33-G35 VanDerWaalsContact O-N 3.09Å; G35-V37 VanDerWaalsContact C-N 3.33Å; G35-V37 PolarHBondContact O-N 3.23Å
36	E	62.2	Low	64	Low	192 Å²	192	136.5 Å²	136.5	90%	0.897	75%	0.747	S	S	*	*			trans	-45.2	106.1	163.3	-112.4	172.1	81.7	0	0	107.1	P34 Q38	P34-E36 PolarHBondContact O-N 3.15Å; E36-Q38 PolarHBondContact O-N 3.02Å
37	V	65.4	Low	64.1	Low	138 Å²	138	137.4 Å²	137.4	84%	0.836	74%	0.744	S	S	*	*			trans	-63.9	102.4	166	172.5	0	0	0	0	103.1	G35 S39	G35-V37 VanDerWaalsContact C-N 3.33Å; G35-V37 PolarHBondContact O-N 3.23Å; V37-S39 PolarHBondContact O-N 3.43Å
38	Q	63.9	Low	64.3	Low	175 Å²	175	136.8 Å²	136.8	82%	0.818	74%	0.741	S	S	*	*			trans	-47.5	120.1	173.7	-70.8	-178.1	-31	0	0	107.1	E36	E36-Q38 PolarHBondContact O-N 3.02Å
39	S	66.1	Low	64.6	Low	102 Å²	102	138.6 Å²	138.6	71%	0.713	74%	0.741	S	S	*	*			trans	-40.4	140.1	176.2	-57	0	0	0	0	110.4	V37 P41	V37-S39 PolarHBondContact O-N 3.43Å; S39-P41 WeakPolarHBondContact O-CD 3.4Å; S39-P41 VanDerWaalsContact O-N 3.14Å
40	P	64.4	Low	64.6	Low	120 Å²	120	147.1 Å²	147.1	78%	0.779	77%	0.767	S	S	*	*			trans	-56.3	124.8	-179	22.9	-32.4	0	0	0	109.3	H42	P40-H42 PolarHBondContact O-N 2.88Å; P40-H42 VanDerWaalsContact O-N 3.12Å
41	P	63.9	Low	64.7	Low	117 Å²	117	145.9 Å²	145.9	76%	0.76	77%	0.765	S	S	*	*			trans	-66.7	117.9	170	25.6	-29.6	0	0	0	108.2	S39	S39-P41 WeakPolarHBondContact O-CD 3.4Å; S39-P41 VanDerWaalsContact O-N 3.14Å
42	H	60.8	Low	64.7	Low	171 Å²	171	143.4 Å²	143.4	79%	0.792	76%	0.758	S	S	*	*			trans	37.6	111.5	144.1	-68.3	-87.5	0	0	0	117.9	P40	P40-H42 PolarHBondContact O-N 2.88Å; P40-H42 VanDerWaalsContact O-N 3.12Å
43	H	60.7	Low	64.8	Low	172 Å²	172	148.4 Å²	148.4	80%	0.796	77%	0.77	S	S	*	*				177.5	124.1	98.4	-121.1	-91.7	0	0	0	108.3	P45	H43-P45 WeakPolarHBondContact O-CD 3.45Å
44	R	62.6	Low	65	Low	220 Å²	220	153.7 Å²	153.7	83%	0.83	78%	0.78	S	S	*	*			trans	-70.7	125.8	151	-75.6	-174	159.4	179.1	-5.3	105.7	D46	R44-D46 VanDerWaalsContact C-N 3.29Å; R44-D46 PolarHBondContact O-N 2.94Å
45	P	63.7	Low	65.1	Low	88 Å²	88	155 Å²	155	57%	0.571	78%	0.775	S	S	*	*			trans	-63.9	107.2	155.2	26.5	-27.8	0	0	0	104.9	H43 W47	H43-P45 WeakPolarHBondContact O-CD 3.45Å; P45-W47 PolarHBondContact O-N 2.69Å
46	D	65.9	Low	65.3	Low	117 Å²	117	161.3 Å²	161.3	63%	0.626	79%	0.785	S	S	*	*			trans	-65	84.9	165.7	-139.4	-99.2	0	0	0	105	R44 Q48	R44-D46 VanDerWaalsContact C-N 3.29Å; R44-D46 PolarHBondContact O-N 2.94Å; D46-Q48 PolarHBondContact O-N 3.06Å; D46-Q48 PolarHBondContact OD1-NE2 3.44Å; D46-Q48 WeakPolarHBondContact OD1-CG 3.32Å; D46-Q48 VanDerWaalsContact OD1-CG 3.24Å
47	W	66.5	Low	65.5	Low	179 Å²	179	159.1 Å²	159.1	68%	0.678	78%	0.776	S	S	*	*			trans	-70.2	68.6	166.4	-70.9	91.9	0	0	0	106.8	P45 W49	P45-W47 PolarHBondContact O-N 2.69Å; W47-W49 VanDerWaalsContact C-N 3.31Å; W47-W49 AromaticContact CE3-CH2 4Å; W47-W49 HydrophobicContact CE3-CH2 4Å; W47-W49 AromaticContact CE3-CZ2 3.68Å; W47-W49 HydrophobicContact CE3-CZ2 3.68Å; W47-W49 AromaticContact CZ3-CH2 3.89Å; W47-W49 HydrophobicContact CZ3-CH2 3.89Å; W47-W49 AromaticContact CZ3-CZ2 3.98Å; W47-W49 HydrophobicContact CZ3-CZ2 3.98Å; W47-W49 PolarHBondContact O-N 3.39Å
48	Q	69.2	Low	65.5	Low	145 Å²	145	160.7 Å²	160.7	68%	0.678	77%	0.772	S	S	*	*			trans	-72.1	97	156.7	-88.4	179.9	96.6	0	0	105.8	D46 F50	D46-Q48 PolarHBondContact O-N 3.06Å; D46-Q48 PolarHBondContact OD1-NE2 3.44Å; D46-Q48 WeakPolarHBondContact OD1-CG 3.32Å; D46-Q48 VanDerWaalsContact OD1-CG 3.24Å; Q48-F50 PolarHBondContact O-N 3.17Å
49	W	73.5	Confident	65.6	Low	209 Å²	209	159.5 Å²	159.5	79%	0.792	77%	0.768	S	S	*	*			trans	-63.6	120.6	159.1	-62.9	101.7	0	0	0	107.1	W47	W47-W49 VanDerWaalsContact C-N 3.31Å; W47-W49 AromaticContact CE3-CH2 4Å; W47-W49 HydrophobicContact CE3-CH2 4Å; W47-W49 AromaticContact CE3-CZ2 3.68Å; W47-W49 HydrophobicContact CE3-CZ2 3.68Å; W47-W49 AromaticContact CZ3-CH2 3.89Å; W47-W49 HydrophobicContact CZ3-CH2 3.89Å; W47-W49 AromaticContact CZ3-CZ2 3.98Å; W47-W49 HydrophobicContact CZ3-CZ2 3.98Å; W47-W49 PolarHBondContact O-N 3.39Å
50	F	70.3	Confident	65.6	Low	274 Å²	274	164.7 Å²	164.7	100%	1.202	77%	0.773	S	S	*	*			trans	-70.4	0	164.9	-71.9	-83.6	0	0	0	110.4	Q48	Q48-F50 PolarHBondContact O-N 3.17Å

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