X5D7R3_HUMAN Loading...

Vasoactive intestinal peptide receptor 2 isoform C

AlphaFold DB , UniProt , Accession X5D7R3, Species HUMAN (Homo sapiens, Human), Gene VIPR2, Length 94 aa.

						>X5D7R3_HUMAN|X5D7R3|VIPR2
MRTLLPPALLTCWLLAPVNSIHPECRFHLEIQEEETKCAVRAEAKMAKPVPDPVREPGLQGLRFLLLPQRLGGRPAVPPRLPRPVLPANGDLGH
					

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	38.4	Very low	53.3	Low	240 Å²	240	126.3 Å²	126.3	100%	1.182	68%	0.677	S	S	*	*				0	102.7	0	-51.2	179.2	-164.1	0	0	105.6	T3	M1-T3 PolarHBondContact O-N 3.1Å
2	R	47.5	Very low	53.1	Low	244 Å²	244	120.8 Å²	120.8	92%	0.921	66%	0.655	S	S	*	*			trans	-81	108.1	-179.8	-80.8	171.5	169.6	144.3	-4.8	106.8	L4	R2-L4 PolarHBondContact O-N 3.49Å
3	T	49.3	Very low	52.9	Low	139 Å²	139	128.8 Å²	128.8	85%	0.853	67%	0.67	S	S	*	*			trans	-60.3	101.5	170.7	8.1	0	0	0	0	107.4	M1 L5	M1-T3 PolarHBondContact O-N 3.1Å; T3-L5 VanDerWaalsContact C-N 3.29Å; T3-L5 PolarHBondContact O-N 2.77Å
4	L	52.5	Low	53.2	Low	157 Å²	157	129.6 Å²	129.6	82%	0.822	68%	0.675	S	S	*	*			trans	-61.4	97.4	167	-100.8	89.2	0	0	0	106.5	R2 P6	R2-L4 PolarHBondContact O-N 3.49Å; L4-P6 WeakPolarHBondContact O-CD 3.38Å
5	L	55.3	Low	53.1	Low	117 Å²	117	131 Å²	131	61%	0.613	68%	0.682	S	S	*	*			trans	-62.1	114.7	168	-167	68.1	0	0	0	106.5	T3 L9 L10	T3-L5 VanDerWaalsContact C-N 3.29Å; T3-L5 PolarHBondContact O-N 2.77Å; L5-L9 HydrophobicContact CD1-CD1 3.88Å; L5-L9 HydrophobicContact CG-CD1 4.5Å; L5-L10 HydrophobicContact CD2-CD1 4.14Å
6	P	60.3	Low	52.7	Low	66 Å²	66	125.9 Å²	125.9	43%	0.429	67%	0.665	S	S	.	*			trans	-58.6	130.8	-174.4	-22.9	32	0	0	0	109.7	L4 A8 L9	L4-P6 WeakPolarHBondContact O-CD 3.38Å; P6-A8 HydrophobicContact CB-CB 4.42Å; P6-A8 PolarHBondContact O-N 2.97Å; P6-L9 PolarHBondContact O-N 3.4Å
7	P	59.3	Low	52.2	Low	107 Å²	107	125.1 Å²	125.1	70%	0.695	67%	0.669	S	S	*	*	H	α-helix	trans	-51.3	-24	175.7	-26.5	32.9	0	0	0	113.4	L9 L10 T11	P7-L9 VanDerWaalsContact C-N 3.32Å; P7-L9 PolarHBondContact O-N 3.48Å; P7-L10 PolarHBondContact O-N 3.23Å; P7-T11 PolarHBondContact O-N 3.49Å; P7-T11 PolarHBondContact O-OG1 3.42Å
8	A	54.6	Low	52.2	Low	64 Å²	64	125.7 Å²	125.7	53%	0.529	68%	0.677	S	S	.	*	H	α-helix	trans	-60.6	-32.5	175.5	0	0	0	0	0	114.4	P6 T11 C12	P6-A8 HydrophobicContact CB-CB 4.42Å; P6-A8 PolarHBondContact O-N 2.97Å; A8-T11 WeakPolarHBondContact CA-OG1 3.41Å; A8-T11 PolarHBondContact O-OG1 3.41Å; A8-C12 PolarHBondContact O-N 3.2Å
9	L	56	Low	52.2	Low	67 Å²	67	127.3 Å²	127.3	35%	0.351	69%	0.686	S	S	.	*	H	α-helix	trans	-74.2	-33.6	178.7	-66.5	179.1	0	0	0	111.8	L5 P6 P7	L5-L9 HydrophobicContact CD1-CD1 3.88Å; L5-L9 HydrophobicContact CG-CD1 4.5Å; P6-L9 PolarHBondContact O-N 3.4Å; P7-L9 VanDerWaalsContact C-N 3.32Å; P7-L9 PolarHBondContact O-N 3.48Å
10	L	57.7	Low	52.2	Low	107 Å²	107	125.6 Å²	125.6	56%	0.56	68%	0.684	S	S	*	*	H	α-helix	trans	-71.2	-39.5	175.9	-117.9	96	0	0	0	111.6	L5 P7 C12 W13	L5-L10 HydrophobicContact CD2-CD1 4.14Å; P7-L10 PolarHBondContact O-N 3.23Å; L10-C12 VanDerWaalsContact C-N 3.32Å; L10-C12 PolarHBondContact O-N 3.34Å; L10-W13 PolarHBondContact O-N 3.03Å
11	T	55.5	Low	52.5	Low	81 Å²	81	125.1 Å²	125.1	50%	0.497	68%	0.679	S	S	.	*	H	α-helix	trans	-70	-29.3	179.4	51.8	0	0	0	0	112.7	P7 A8 W13 L14 L15	P7-T11 PolarHBondContact O-N 3.49Å; P7-T11 PolarHBondContact O-OG1 3.42Å; A8-T11 WeakPolarHBondContact CA-OG1 3.41Å; A8-T11 PolarHBondContact O-OG1 3.41Å; T11-W13 VanDerWaalsContact C-N 3.32Å; T11-W13 PolarHBondContact O-N 3.31Å; T11-L14 PolarHBondContact O-N 2.92Å; T11-L15 PolarHBondContact O-N 3.16Å
12	C	51.1	Low	53.3	Low	60 Å²	60	118.9 Å²	118.9	41%	0.405	65%	0.647	S	S	.	*	H	α-helix	trans	-68.9	-30.8	177.9	-163.1	0	0	0	0	112.4	A8 L10	A8-C12 PolarHBondContact O-N 3.2Å; L10-C12 VanDerWaalsContact C-N 3.32Å; L10-C12 PolarHBondContact O-N 3.34Å
13	W	50.7	Low	53.8	Low	225 Å²	225	112 Å²	112	85%	0.852	64%	0.635	S	S	*	*	H	α-helix	trans	-73.7	-25.1	176	-96.6	85.9	0	0	0	114.5	L10 T11	L10-W13 PolarHBondContact O-N 3.03Å; T11-W13 VanDerWaalsContact C-N 3.32Å; T11-W13 PolarHBondContact O-N 3.31Å
14	L	56.3	Low	54.1	Low	141 Å²	141	111.7 Å²	111.7	74%	0.738	62%	0.623	S	S	*	*	H	α-helix	trans	-96.6	-19.7	-172.1	-78.2	162.2	0	0	0	114.5	T11	T11-L14 PolarHBondContact O-N 2.92Å
15	L	52.8	Low	54.3	Low	150 Å²	150	105.7 Å²	105.7	79%	0.785	59%	0.594	S	S	*	*	H	α-helix	trans	-110	-6.3	-170.7	-91.1	85.4	0	0	0	116.1	T11	T11-L15 PolarHBondContact O-N 3.16Å
16	A	45.8	Very low	54.4	Low	49 Å²	49	108.5 Å²	108.5	41%	0.405	60%	0.596	S	S	.	*			trans	-128.8	112.7	-175.4	0	0	0	0	0	111.9	V18	A16-V18 PolarHBondContact O-N 2.8Å; A16-V18 VanDerWaalsContact O-N 3.1Å
17	P	45.2	Very low	54.2	Low	113 Å²	113	111.3 Å²	111.3	73%	0.734	60%	0.602	S	S	*	*			trans	-68.5	109	169	27	-27.5	0	0	0	109	N19	P17-N19 VanDerWaalsContact C-N 3.31Å; P17-N19 PolarHBondContact O-N 3.03Å
18	V	51.7	Low	54.5	Low	136 Å²	136	110.7 Å²	110.7	82%	0.824	59%	0.59	S	S	*	*	S	Bend	trans	25.3	46.7	148.1	-75.1	0	0	0	0	119.1	A16	A16-V18 PolarHBondContact O-N 2.8Å; A16-V18 VanDerWaalsContact O-N 3.1Å
19	N	51	Low	54.8	Low	156 Å²	156	112.3 Å²	112.3	83%	0.834	59%	0.589	S	S	*	*	S	Bend	trans	-152.3	5.6	162.6	-140.5	-11.9	0	0	0	116.4	P17	P17-N19 VanDerWaalsContact C-N 3.31Å; P17-N19 PolarHBondContact O-N 3.03Å
20	S	53.3	Low	55.1	Low	93 Å²	93	114.4 Å²	114.4	65%	0.65	60%	0.597	S	S	*	*			trans	-142.1	60.6	174.3	65.4	0	0	0	0	109.6	H22	S20-H22 PolarHBondContact O-N 2.94Å
21	I	58.5	Low	55.5	Low	115 Å²	115	112.6 Å²	112.6	59%	0.59	59%	0.587	S	S	*	*			trans	-61.6	113.1	166.5	-61.1	172.4	0	0	0	105.7	C25 R26	I21-C25 HydrophobicContact CG2-CB 3.81Å; I21-R26 HydrophobicContact CG2-CB 4.34Å
22	H	56	Low	55.6	Low	109 Å²	109	114.6 Å²	114.6	51%	0.505	59%	0.591	S	S	.	*			trans	-53.4	138.9	177.9	-158.8	-110.6	0	0	0	108.6	S20 E24 C25 R26	S20-H22 PolarHBondContact O-N 2.94Å; H22-E24 PolarHBondContact O-N 2.9Å; H22-C25 WeakPolarHBondContact O-CA 3.44Å; H22-C25 WeakPolarHBondContact O-CB 3.2Å; H22-C25 PolarHBondContact O-N 2.71Å; H22-R26 PolarHBondContact O-N 3.04Å; H22-R26 VanDerWaalsContact O-N 3.16Å
23	P	56.9	Low	56.4	Low	101 Å²	101	118.8 Å²	118.8	66%	0.656	60%	0.604	S	S	*	*	H	α-helix	trans	-55.5	-30.5	-176.1	21.1	-33.1	0	0	0	112.4	R26 F27	P23-R26 PolarHBondContact O-N 3.04Å; P23-F27 PolarHBondContact O-N 3.29Å
24	E	55.4	Low	56.9	Low	131 Å²	131	114 Å²	114	61%	0.612	59%	0.592	S	S	*	*	H	α-helix	trans	-65	-38.2	174.2	-143.5	163.6	87.3	0	0	112.2	H22 F27 H28	H22-E24 PolarHBondContact O-N 2.9Å; E24-F27 PolarHBondContact O-N 3.27Å; E24-H28 PolarHBondContact O-N 3.49Å; E24-H28 PolarHBondContact O-ND1 3.48Å
25	C	56.9	Low	57.3	Low	31 Å²	31	113.3 Å²	113.3	21%	0.209	59%	0.585	C	S	.	*	H	α-helix	trans	-73.3	-30.8	176.6	-61.2	0	0	0	0	112.8	I21 H22 F27 H28 L29	I21-C25 HydrophobicContact CG2-CB 3.81Å; H22-C25 WeakPolarHBondContact O-CA 3.44Å; H22-C25 WeakPolarHBondContact O-CB 3.2Å; H22-C25 PolarHBondContact O-N 2.71Å; C25-F27 VanDerWaalsContact C-N 3.34Å; C25-H28 PolarHBondContact O-N 3.34Å; C25-L29 PolarHBondContact O-N 3.47Å
26	R	57.1	Low	57.7	Low	176 Å²	176	110.1 Å²	110.1	66%	0.664	57%	0.572	S	S	*	*	H	α-helix	trans	-63.7	-40.8	173.6	-177.4	-179.4	175	173.7	-0.2	111.4	I21 H22 P23 H28 L29 E30	I21-R26 HydrophobicContact CG2-CB 4.34Å; H22-R26 PolarHBondContact O-N 3.04Å; H22-R26 VanDerWaalsContact O-N 3.16Å; P23-R26 PolarHBondContact O-N 3.04Å; R26-H28 VanDerWaalsContact C-N 3.34Å; R26-H28 PolarHBondContact O-N 3.41Å; R26-L29 PolarHBondContact O-N 3.43Å; R26-E30 PolarHBondContact O-N 3.37Å
27	F	57.3	Low	58.4	Low	126 Å²	126	115.4 Å²	115.4	55%	0.553	59%	0.586	S	S	*	*	H	α-helix	trans	-65.4	-38.1	-179.9	-151.9	-104.3	0	0	0	112.1	P23 E24 C25 L29 E30 I31	P23-F27 PolarHBondContact O-N 3.29Å; E24-F27 PolarHBondContact O-N 3.27Å; C25-F27 VanDerWaalsContact C-N 3.34Å; F27-L29 PolarHBondContact O-N 3.46Å; F27-E30 PolarHBondContact O-N 2.98Å; F27-I31 HydrophobicContact CD1-CD1 3.41Å; F27-I31 VanDerWaalsContact CD1-CD1 3.41Å; F27-I31 HydrophobicContact CD1-CG1 4.17Å; F27-I31 HydrophobicContact CE1-CD1 3.58Å; F27-I31 HydrophobicContact CE1-CG1 4.21Å; F27-I31 HydrophobicContact CG-CD1 4.42Å; F27-I31 WeakPolarHBondContact O-CD1 3.45Å; F27-I31 VanDerWaalsContact O-CG1 3.26Å; F27-I31 WeakPolarHBondContact O-CG1 3.39Å; F27-I31 PolarHBondContact O-N 2.95Å
28	H	65.2	Low	59.1	Low	94 Å²	94	113.5 Å²	113.5	44%	0.435	57%	0.574	S	S	.	*	H	α-helix	trans	-67.1	-35.6	176	-71.1	89	0	0	0	113	E24 C25 R26 Q32	E24-H28 PolarHBondContact O-N 3.49Å; E24-H28 PolarHBondContact O-ND1 3.48Å; C25-H28 PolarHBondContact O-N 3.34Å; R26-H28 VanDerWaalsContact C-N 3.34Å; R26-H28 PolarHBondContact O-N 3.41Å; H28-Q32 WeakPolarHBondContact O-CB 3.48Å; H28-Q32 WeakPolarHBondContact O-CG 3.37Å; H28-Q32 PolarHBondContact O-N 3.41Å
29	L	60.5	Low	59.5	Low	98 Å²	98	109.2 Å²	109.2	51%	0.513	55%	0.553	S	S	.	*	H	α-helix	trans	-66.7	-42.3	174.3	-78.9	155.7	0	0	0	111.3	C25 R26 F27 Q32 E33	C25-L29 PolarHBondContact O-N 3.47Å; R26-L29 PolarHBondContact O-N 3.43Å; F27-L29 PolarHBondContact O-N 3.46Å; L29-Q32 PolarHBondContact O-N 3.24Å; L29-E33 PolarHBondContact O-N 3.37Å
30	E	61.6	Low	59.9	Low	111 Å²	111	106.6 Å²	106.6	52%	0.519	54%	0.542	S	S	.	.	H	α-helix	trans	-65	-42.3	177.7	-169.4	169	79.4	0	0	111.9	R26 F27 E33 E34	R26-E30 PolarHBondContact O-N 3.37Å; F27-E30 PolarHBondContact O-N 2.98Å; E30-E33 PolarHBondContact O-N 3.04Å; E30-E34 PolarHBondContact O-N 2.93Å
31	I	67.2	Low	60.1	Low	68 Å²	68	110.4 Å²	110.4	35%	0.349	54%	0.542	S	S	.	.	H	α-helix	trans	-64	-44.8	175.1	-67.5	163.3	0	0	0	111.1	F27 E33 E34 E35	F27-I31 HydrophobicContact CD1-CD1 3.41Å; F27-I31 VanDerWaalsContact CD1-CD1 3.41Å; F27-I31 HydrophobicContact CD1-CG1 4.17Å; F27-I31 HydrophobicContact CE1-CD1 3.58Å; F27-I31 HydrophobicContact CE1-CG1 4.21Å; F27-I31 HydrophobicContact CG-CD1 4.42Å; F27-I31 WeakPolarHBondContact O-CD1 3.45Å; F27-I31 VanDerWaalsContact O-CG1 3.26Å; F27-I31 WeakPolarHBondContact O-CG1 3.39Å; F27-I31 PolarHBondContact O-N 2.95Å; I31-E33 VanDerWaalsContact C-N 3.3Å; I31-E33 PolarHBondContact O-N 2.82Å; I31-E34 PolarHBondContact O-N 2.81Å; I31-E34 VanDerWaalsContact O-N 3.13Å; I31-E35 HydrophobicContact CG2-CG 4.07Å; I31-E35 WeakPolarHBondContact O-CB 3.31Å; I31-E35 WeakPolarHBondContact O-CG 3.44Å; I31-E35 PolarHBondContact O-N 3.39Å
32	Q	57.9	Low	60	Low	124 Å²	124	106.7 Å²	106.7	58%	0.579	53%	0.529	S	S	*	.	H	α-helix	trans	-63.3	-37.5	179.2	-79.9	-173.9	35.2	0	0	112.5	H28 L29 E34 T36	H28-Q32 WeakPolarHBondContact O-CB 3.48Å; H28-Q32 WeakPolarHBondContact O-CG 3.37Å; H28-Q32 PolarHBondContact O-N 3.41Å; L29-Q32 PolarHBondContact O-N 3.24Å; Q32-E34 VanDerWaalsContact C-N 3.34Å; Q32-T36 WeakPolarHBondContact O-CB 3.5Å; Q32-T36 VanDerWaalsContact O-CG2 3.31Å; Q32-T36 WeakPolarHBondContact O-CG2 3.36Å; Q32-T36 PolarHBondContact O-N 3.01Å; Q32-T36 PolarHBondContact O-OG1 3.38Å
33	E	67.6	Low	59.9	Low	147 Å²	147	107.9 Å²	107.9	69%	0.687	54%	0.535	S	S	*	.	H	α-helix	trans	-64.2	-41.4	173.5	-172.1	179.5	89.7	0	0	111.2	L29 E30 I31 T36 K37	L29-E33 PolarHBondContact O-N 3.37Å; E30-E33 PolarHBondContact O-N 3.04Å; I31-E33 VanDerWaalsContact C-N 3.3Å; I31-E33 PolarHBondContact O-N 2.82Å; E33-T36 WeakPolarHBondContact CA-OG1 3.44Å; E33-T36 PolarHBondContact O-OG1 3.36Å; E33-K37 WeakPolarHBondContact O-CB 3.48Å; E33-K37 PolarHBondContact O-N 3.13Å
34	E	61.7	Low	60	Low	126 Å²	126	106.5 Å²	106.5	59%	0.589	53%	0.532	S	S	*	.	H	α-helix	trans	-66	-45.6	176.9	-158.2	-148.3	98.5	0	0	112.3	E30 I31 Q32 T36 K37 C38	E30-E34 PolarHBondContact O-N 2.93Å; I31-E34 PolarHBondContact O-N 2.81Å; I31-E34 VanDerWaalsContact O-N 3.13Å; Q32-E34 VanDerWaalsContact C-N 3.34Å; E34-T36 VanDerWaalsContact C-N 3.34Å; E34-T36 PolarHBondContact O-N 2.87Å; E34-K37 PolarHBondContact O-N 3.43Å; E34-C38 WeakPolarHBondContact O-CB 3.26Å; E34-C38 PolarHBondContact O-N 2.9Å; E34-C38 PolarHBondContact O-SG 3.01Å
35	E	63	Low	59.9	Low	125 Å²	125	107.7 Å²	107.7	58%	0.584	54%	0.535	S	S	*	.	H	α-helix	trans	-62.7	-40.3	179.1	-73.3	-167.9	112.2	0	0	111.7	I31 C38 A39	I31-E35 HydrophobicContact CG2-CG 4.07Å; I31-E35 WeakPolarHBondContact O-CB 3.31Å; I31-E35 WeakPolarHBondContact O-CG 3.44Å; I31-E35 PolarHBondContact O-N 3.39Å; E35-C38 PolarHBondContact O-N 3.07Å; E35-A39 WeakPolarHBondContact O-CB 3.39Å; E35-A39 PolarHBondContact O-N 3.1Å
36	T	62.6	Low	59.7	Low	84 Å²	84	113.5 Å²	113.5	52%	0.515	56%	0.561	S	S	.	*	H	α-helix	trans	-68.6	-38.1	176.9	48.7	0	0	0	0	112.1	Q32 E33 E34 C38 A39 V40	Q32-T36 WeakPolarHBondContact O-CB 3.5Å; Q32-T36 VanDerWaalsContact O-CG2 3.31Å; Q32-T36 WeakPolarHBondContact O-CG2 3.36Å; Q32-T36 PolarHBondContact O-N 3.01Å; Q32-T36 PolarHBondContact O-OG1 3.38Å; E33-T36 WeakPolarHBondContact CA-OG1 3.44Å; E33-T36 PolarHBondContact O-OG1 3.36Å; E34-T36 VanDerWaalsContact C-N 3.34Å; E34-T36 PolarHBondContact O-N 2.87Å; T36-C38 VanDerWaalsContact C-N 3.34Å; T36-A39 PolarHBondContact O-N 3.26Å; T36-V40 VanDerWaalsContact O-CG2 3.25Å; T36-V40 WeakPolarHBondContact O-CG2 3.37Å; T36-V40 PolarHBondContact O-N 2.9Å
37	K	60.8	Low	59.6	Low	160 Å²	160	108.9 Å²	108.9	70%	0.696	56%	0.56	S	S	*	*	H	α-helix	trans	-65.1	-38.8	173.8	-174.5	178	177.6	-178.5	0	112	E33 E34 R41	E33-K37 WeakPolarHBondContact O-CB 3.48Å; E33-K37 PolarHBondContact O-N 3.13Å; E34-K37 PolarHBondContact O-N 3.43Å; K37-R41 WeakPolarHBondContact O-CB 3.25Å; K37-R41 PolarHBondContact O-N 2.97Å; K37-R41 VanDerWaalsContact O-N 3.1Å
38	C	59.8	Low	59	Low	72 Å²	72	111.8 Å²	111.8	49%	0.486	57%	0.573	S	S	.	*	H	α-helix	trans	-66.8	-42.1	174.7	-79.7	0	0	0	0	112	E34 E35 T36 R41 A42	E34-C38 WeakPolarHBondContact O-CB 3.26Å; E34-C38 PolarHBondContact O-N 2.9Å; E34-C38 PolarHBondContact O-SG 3.01Å; E35-C38 PolarHBondContact O-N 3.07Å; T36-C38 VanDerWaalsContact C-N 3.34Å; C38-R41 PolarHBondContact O-N 2.86Å; C38-A42 WeakPolarHBondContact O-CB 3.4Å; C38-A42 PolarHBondContact O-N 3.4Å
39	A	58.7	Low	58.3	Low	47 Å²	47	112.6 Å²	112.6	39%	0.388	59%	0.587	S	S	.	*	H	α-helix	trans	-58.8	-55.6	174	0	0	0	0	0	110.6	E35 T36 R41 A42 E43	E35-A39 WeakPolarHBondContact O-CB 3.39Å; E35-A39 PolarHBondContact O-N 3.1Å; T36-A39 PolarHBondContact O-N 3.26Å; A39-R41 PolarHBondContact O-N 3.49Å; A39-R41 VanDerWaalsContact O-N 3.1Å; A39-A42 CarbonylContact O-C 3.58Å; A39-A42 WeakPolarHBondContact O-CA 3.44Å; A39-A42 VanDerWaalsContact O-CB 3.31Å; A39-A42 WeakPolarHBondContact O-CB 3.24Å; A39-A42 PolarHBondContact O-N 3.04Å; A39-E43 VanDerWaalsContact O-CG 3.24Å; A39-E43 WeakPolarHBondContact O-CG 3.3Å; A39-E43 PolarHBondContact O-N 3.34Å
40	V	60.9	Low	57.8	Low	101 Å²	101	114 Å²	114	61%	0.612	60%	0.599	S	S	*	*	H	α-helix	trans	-54.3	-36.7	178.7	172	0	0	0	0	112.3	T36 A44	T36-V40 VanDerWaalsContact O-CG2 3.25Å; T36-V40 WeakPolarHBondContact O-CG2 3.37Å; T36-V40 PolarHBondContact O-N 2.9Å; V40-A44 WeakPolarHBondContact O-CB 3.43Å; V40-A44 PolarHBondContact O-N 3.3Å; V40-A44 VanDerWaalsContact O-N 3.1Å
41	R	56	Low	57.4	Low	172 Å²	172	114.3 Å²	114.3	65%	0.649	61%	0.611	S	S	*	*	H	α-helix	trans	-74.6	-30.5	176.6	-160.5	176.4	-157.5	-135.1	4.6	113.1	K37 C38 A39 K45	K37-R41 WeakPolarHBondContact O-CB 3.25Å; K37-R41 PolarHBondContact O-N 2.97Å; K37-R41 VanDerWaalsContact O-N 3.1Å; C38-R41 PolarHBondContact O-N 2.86Å; A39-R41 PolarHBondContact O-N 3.49Å; A39-R41 VanDerWaalsContact O-N 3.1Å; R41-K45 WeakPolarHBondContact O-CD 3.49Å; R41-K45 VanDerWaalsContact O-CG 3.3Å; R41-K45 WeakPolarHBondContact O-CG 3.31Å; R41-K45 PolarHBondContact O-N 3.1Å
42	A	57.1	Low	56.7	Low	37 Å²	37	117.5 Å²	117.5	31%	0.306	63%	0.628	S	S	.	*	H	α-helix	trans	-69.1	-46.2	172	0	0	0	0	0	110.5	C38 A39 A44 K45 M46	C38-A42 WeakPolarHBondContact O-CB 3.4Å; C38-A42 PolarHBondContact O-N 3.4Å; A39-A42 CarbonylContact O-C 3.58Å; A39-A42 WeakPolarHBondContact O-CA 3.44Å; A39-A42 VanDerWaalsContact O-CB 3.31Å; A39-A42 WeakPolarHBondContact O-CB 3.24Å; A39-A42 PolarHBondContact O-N 3.04Å; A42-A44 VanDerWaalsContact C-N 3.29Å; A42-A44 PolarHBondContact O-N 2.92Å; A42-K45 PolarHBondContact O-N 3.14Å; A42-K45 VanDerWaalsContact O-N 3.08Å; A42-M46 VanDerWaalsContact O-CG 3.31Å; A42-M46 WeakPolarHBondContact O-CG 3.32Å; A42-M46 PolarHBondContact O-N 3.3Å
43	E	54.8	Low	56.6	Low	134 Å²	134	117 Å²	117	63%	0.626	64%	0.635	S	S	*	*	H	α-helix	trans	-57.3	-43.8	175.4	-36.8	-58.6	86.7	0	0	111.2	A39 K45 M46 A47	A39-E43 VanDerWaalsContact O-CG 3.24Å; A39-E43 WeakPolarHBondContact O-CG 3.3Å; A39-E43 PolarHBondContact O-N 3.34Å; E43-K45 PolarHBondContact O-N 3.1Å; E43-M46 PolarHBondContact O-N 3.2Å; E43-M46 VanDerWaalsContact O-N 3.14Å; E43-A47 PolarHBondContact O-N 3.08Å
44	A	57	Low	55.6	Low	72 Å²	72	115.7 Å²	115.7	60%	0.595	64%	0.637	S	S	*	*	H	α-helix	trans	-66	-25.5	180	0	0	0	0	0	113.4	V40 A42	V40-A44 WeakPolarHBondContact O-CB 3.43Å; V40-A44 PolarHBondContact O-N 3.3Å; V40-A44 VanDerWaalsContact O-N 3.1Å; A42-A44 VanDerWaalsContact C-N 3.29Å; A42-A44 PolarHBondContact O-N 2.92Å
45	K	55.2	Low	54.8	Low	156 Å²	156	121 Å²	121	68%	0.678	65%	0.652	S	S	*	*	H	α-helix	trans	-85.4	-16.3	176.2	-73.5	168.3	178.4	-108.5	0	113	R41 A42 E43	R41-K45 WeakPolarHBondContact O-CD 3.49Å; R41-K45 VanDerWaalsContact O-CG 3.3Å; R41-K45 WeakPolarHBondContact O-CG 3.31Å; R41-K45 PolarHBondContact O-N 3.1Å; A42-K45 PolarHBondContact O-N 3.14Å; A42-K45 VanDerWaalsContact O-N 3.08Å; E43-K45 PolarHBondContact O-N 3.1Å
46	M	52.2	Low	53.9	Low	153 Å²	153	122.2 Å²	122.2	75%	0.754	66%	0.658	S	S	*	*	H	α-helix	trans	-95	-0.2	176.4	-51	-144.4	-164.4	0	0	113.2	A42 E43 K48	A42-M46 VanDerWaalsContact O-CG 3.31Å; A42-M46 WeakPolarHBondContact O-CG 3.32Å; A42-M46 PolarHBondContact O-N 3.3Å; E43-M46 PolarHBondContact O-N 3.2Å; E43-M46 VanDerWaalsContact O-N 3.14Å; M46-K48 VanDerWaalsContact C-N 3.25Å; M46-K48 PolarHBondContact O-N 3.32Å
47	A	53.6	Low	53.3	Low	79 Å²	79	123.7 Å²	123.7	65%	0.653	67%	0.669	S	S	*	*			trans	-80.5	66.5	174.1	0	0	0	0	0	112.2	E43	E43-A47 PolarHBondContact O-N 3.08Å
48	K	46.5	Very low	52.5	Low	188 Å²	188	119.3 Å²	119.3	82%	0.817	67%	0.669	S	S	*	*			trans	-126	100.3	142.3	-170.6	156.4	-176.4	169.7	0	107.3	M46 V50	M46-K48 VanDerWaalsContact C-N 3.25Å; M46-K48 PolarHBondContact O-N 3.32Å; K48-V50 PolarHBondContact O-N 3.5Å; K48-V50 VanDerWaalsContact O-N 3.12Å
49	P	48.7	Very low	52.4	Low	111 Å²	111	123.9 Å²	123.9	72%	0.721	69%	0.688	S	S	*	*			trans	-64.7	118.3	171.8	26.1	-29.4	0	0	0	107.4	P51	P49-P51 WeakPolarHBondContact O-CD 3.31Å
50	V	50.8	Low	52.4	Low	128 Å²	128	129.9 Å²	129.9	78%	0.776	71%	0.708	S	S	*	*			trans	-62.5	121.5	158.1	159.9	0	0	0	0	105.9	K48 D52	K48-V50 PolarHBondContact O-N 3.5Å; K48-V50 VanDerWaalsContact O-N 3.12Å; V50-D52 PolarHBondContact O-N 3.11Å; V50-D52 VanDerWaalsContact O-N 3.13Å
51	P	54	Low	51.8	Low	117 Å²	117	128 Å²	128	76%	0.76	71%	0.71	S	S	*	*			trans	-67.6	113.3	171.1	26.7	-30.2	0	0	0	107.9	P49	P49-P51 WeakPolarHBondContact O-CD 3.31Å
52	D	52.4	Low	52	Low	135 Å²	135	128.7 Å²	128.7	72%	0.722	73%	0.725	S	S	*	*			trans	-58.5	130.2	167.5	-157.6	-88.9	0	0	0	108.1	V50 V54	V50-D52 PolarHBondContact O-N 3.11Å; V50-D52 VanDerWaalsContact O-N 3.13Å; D52-V54 PolarHBondContact O-N 2.98Å
53	P	54.3	Low	51.9	Low	112 Å²	112	137.3 Å²	137.3	73%	0.727	75%	0.75	S	S	*	*			trans	-66.4	104.8	174.3	25.9	-30.6	0	0	0	108.8	R55	P53-R55 PolarHBondContact O-N 3.42Å
54	V	46.5	Very low	51.8	Low	120 Å²	120	139.7 Å²	139.7	73%	0.727	76%	0.758	S	S	*	*			trans	-41.9	106.7	168.1	167.7	0	0	0	0	109.5	D52 E56	D52-V54 PolarHBondContact O-N 2.98Å; V54-E56 PolarHBondContact O-N 2.81Å
55	R	46	Very low	51.5	Low	238 Å²	238	142.1 Å²	142.1	90%	0.898	76%	0.761	S	S	*	*			trans	-84.7	108	165.4	-167.4	175.8	79.8	-174.7	4	107.5	P53	P53-R55 PolarHBondContact O-N 3.42Å
56	E	43.2	Very low	51.5	Low	150 Å²	150	143.1 Å²	143.1	70%	0.701	77%	0.772	S	S	*	*			trans	-47.8	147.5	178.4	-69	-78.4	86.8	0	0	113.4	V54 G58	V54-E56 PolarHBondContact O-N 2.81Å; E56-G58 PolarHBondContact O-N 3.28Å
57	P	50.8	Low	51.5	Low	115 Å²	115	143 Å²	143	75%	0.747	77%	0.774	S	S	*	*			trans	-78.6	106.2	-168.5	28.8	-33.2	0	0	0	113.5	L59	P57-L59 PolarHBondContact O-N 3.26Å
58	G	43.7	Very low	51.5	Low	69 Å²	69	144.2 Å²	144.2	71%	0.711	78%	0.775	S	S	*	*			trans	-76	101.3	163.8	0	0	0	0	0	111.5	E56 Q60	E56-G58 PolarHBondContact O-N 3.28Å; G58-Q60 PolarHBondContact O-N 3.5Å
59	L	58.2	Low	51.5	Low	168 Å²	168	143.4 Å²	143.4	88%	0.88	77%	0.774	S	S	*	*	T	Hydrogen-bonded Turn	trans	-63.3	53.2	-176.3	-147.7	154.1	0	0	0	114.8	P57	P57-L59 PolarHBondContact O-N 3.26Å
60	Q	58.8	Low	51.7	Low	172 Å²	172	148.6 Å²	148.6	80%	0.804	78%	0.779	S	S	*	*	T	Hydrogen-bonded Turn	trans	-126.7	-11.2	-170.4	-65.2	-91.3	73.3	0	0	115.4	G58	G58-Q60 PolarHBondContact O-N 3.5Å
61	G	48.5	Very low	51.5	Low	63 Å²	63	150 Å²	150	65%	0.649	78%	0.782	S	S	*	*	S	Bend	trans	-95.7	-27.8	-172.4	0	0	0	0	0	116.3	R63	G61-R63 PolarHBondContact O-N 2.94Å; G61-R63 VanDerWaalsContact O-N 3.11Å
62	L	59.4	Low	51.3	Low	185 Å²	185	148.4 Å²	148.4	97%	0.969	79%	0.787	S	S	*	*	T	Hydrogen-bonded Turn	trans	-78.7	7.1	-172.6	-73.1	165.6	0	0	0	113.9
63	R	56.4	Low	51.2	Low	219 Å²	219	145.3 Å²	145.3	83%	0.826	79%	0.787	S	S	*	*	T	Hydrogen-bonded Turn	trans	-107.7	13.9	-176.8	-135.5	-180	-178.4	-93.6	1.5	114.2	G61 L65	G61-R63 PolarHBondContact O-N 2.94Å; G61-R63 VanDerWaalsContact O-N 3.11Å; R63-L65 VanDerWaalsContact O-CG 3.32Å; R63-L65 WeakPolarHBondContact O-CG 3.38Å
64	F	51.3	Low	51.2	Low	184 Å²	184	151.5 Å²	151.5	81%	0.807	80%	0.795	S	S	*	*	S	Bend	trans	-105	72.6	157.9	-81.9	-90.5	0	0	0	108.2
65	L	50.9	Low	51.4	Low	123 Å²	123	151.9 Å²	151.9	64%	0.644	80%	0.801	S	S	*	*				65	81.5	99.3	-63.1	158.7	0	0	0	109.7	R63 L67	R63-L65 VanDerWaalsContact O-CG 3.32Å; R63-L65 WeakPolarHBondContact O-CG 3.38Å; L65-L67 PolarHBondContact O-N 2.94Å
66	L	55.8	Low	51.8	Low	176 Å²	176	145.3 Å²	145.3	92%	0.921	80%	0.797	S	S	*	*				41.2	39.7	78.4	-134.6	92.1	0	0	0	113.8
67	L	51.8	Low	52.5	Low	152 Å²	152	144.2 Å²	144.2	80%	0.796	80%	0.8	S	S	*	*			trans	-125	109.8	169.5	-140.6	75.8	0	0	0	110.4	L65	L65-L67 PolarHBondContact O-N 2.94Å
68	P	53	Low	52.7	Low	104 Å²	104	143.6 Å²	143.6	68%	0.675	80%	0.796	S	S	*	*			trans	-90.1	115.8	171.6	32.3	-23.9	0	0	0	108.3
69	Q	46.9	Very low	53.3	Low	171 Å²	171	146.3 Å²	146.3	80%	0.799	80%	0.802	S	S	*	*			trans	-164.7	114.5	149.3	-68.4	-48.8	16.6	0	0	109.8
70	R	53.3	Low	53.3	Low	219 Å²	219	149.9 Å²	149.9	83%	0.826	80%	0.803	S	S	*	*				48.6	92.8	82.4	-100	-98.6	-175.5	-166.9	-1.8	112.8
71	L	46.5	Very low	53.4	Low	157 Å²	157	149.3 Å²	149.3	82%	0.822	81%	0.805	S	S	*	*				167.1	142.1	121.8	-110.3	81.8	0	0	0	109.3
72	G	49.7	Very low	53.7	Low	84 Å²	84	152 Å²	152	87%	0.866	81%	0.81	S	S	*	*			trans	-67.4	160	-175.1	0	0	0	0	0	114.7
73	G	50.8	Low	53.9	Low	70 Å²	70	154.3 Å²	154.3	72%	0.722	81%	0.807	S	S	*	*			trans	154.7	107.6	164.4	0	0	0	0	0	115.2
74	R	54.5	Low	53.5	Low	242 Å²	242	149.2 Å²	149.2	91%	0.913	80%	0.802	S	S	*	*			trans	81	133.5	155.6	-54.5	173.8	78.1	-173	4.5	118.1	A76	R74-A76 PolarHBondContact O-N 3.13Å
75	P	49.8	Very low	54	Low	129 Å²	129	147.3 Å²	147.3	84%	0.838	81%	0.805	S	S	*	*	P	Polyproline II helix	trans	-69.8	130.1	172.8	27.5	-30.6	0	0	0	110.6	V77	P75-V77 PolarHBondContact O-N 3.12Å
76	A	54.2	Low	54.5	Low	99 Å²	99	148.2 Å²	148.2	82%	0.818	81%	0.81	S	S	*	*	P	Polyproline II helix	trans	-67.8	122.1	175.5	0	0	0	0	0	110.3	R74	R74-A76 PolarHBondContact O-N 3.13Å
77	V	58.3	Low	54.5	Low	127 Å²	127	145 Å²	145	77%	0.77	80%	0.799	S	S	*	*	P	Polyproline II helix	trans	-65.5	131.6	166.1	169.6	0	0	0	0	108.1	P75	P75-V77 PolarHBondContact O-N 3.12Å
78	P	55.9	Low	54.7	Low	103 Å²	103	142.8 Å²	142.8	67%	0.669	80%	0.803	S	S	*	*	P	Polyproline II helix	trans	-67.9	147	176.3	27	-32.8	0	0	0	111.1	R80	P78-R80 PolarHBondContact O-N 3.35Å
79	P	56.2	Low	54.8	Low	126 Å²	126	145.2 Å²	145.2	82%	0.818	81%	0.81	S	S	*	*	P	Polyproline II helix	trans	-65.7	134.7	-178.4	26.3	-32.3	0	0	0	111	L81	P79-L81 PolarHBondContact O-N 3.48Å
80	R	57.5	Low	55.1	Low	243 Å²	243	141 Å²	141	92%	0.917	81%	0.812	S	S	*	*	P	Polyproline II helix	trans	-67.8	120.8	177.6	-64.9	-170.9	-170.5	-97.9	4.3	109.9	P78	P78-R80 PolarHBondContact O-N 3.35Å
81	L	61.1	Low	55.2	Low	160 Å²	160	138.3 Å²	138.3	84%	0.838	81%	0.814	S	S	*	*	P	Polyproline II helix	trans	-62	145.3	167.1	-84	143.6	0	0	0	110.6	P79 R83	P79-L81 PolarHBondContact O-N 3.48Å; L81-R83 PolarHBondContact O-N 3.44Å
82	P	54.6	Low	55.5	Low	118 Å²	118	138.8 Å²	138.8	77%	0.766	82%	0.817	S	S	*	*	P	Polyproline II helix	trans	-59.9	133.8	174.2	-17.1	29	0	0	0	110.6
83	R	62.4	Low	55.4	Low	235 Å²	235	138.2 Å²	138.2	89%	0.887	81%	0.811	S	S	*	*	P	Polyproline II helix	trans	-65.8	135.9	177.3	-84.1	179.5	149.8	164.6	-7.4	110.6	L81 V85	L81-R83 PolarHBondContact O-N 3.44Å; R83-V85 PolarHBondContact O-N 3.49Å
84	P	49.3	Very low	55	Low	111 Å²	111	147.5 Å²	147.5	72%	0.721	84%	0.835	S	S	*	*	P	Polyproline II helix	trans	-69.4	130.1	169.6	25.5	-27.6	0	0	0	109.9	L86	P84-L86 PolarHBondContact O-N 3.34Å
85	V	61.9	Low	55.1	Low	144 Å²	144	142.8 Å²	142.8	87%	0.873	83%	0.831	S	S	*	*			trans	-78.8	106.6	171.7	175.9	0	0	0	0	107.6	R83	R83-V85 PolarHBondContact O-N 3.49Å
86	L	61	Low	55.3	Low	143 Å²	143	143.5 Å²	143.5	75%	0.749	83%	0.831	S	S	*	*	P	Polyproline II helix	trans	-84.1	137.5	167.6	-81.7	135.9	0	0	0	109.1	P84	P84-L86 PolarHBondContact O-N 3.34Å
87	P	54.8	Low	55.4	Low	108 Å²	108	145.9 Å²	145.9	70%	0.701	83%	0.831	S	S	*	*	P	Polyproline II helix	trans	-65.7	136.7	168.9	27.4	-31.1	0	0	0	109.7	N89	P87-N89 PolarHBondContact O-N 3.25Å
88	A	57	Low	55.2	Low	105 Å²	105	147.1 Å²	147.1	87%	0.868	84%	0.835	S	S	*	*	P	Polyproline II helix	trans	-62.3	119	-179.8	0	0	0	0	0	110.3
89	N	55.2	Low	55.2	Low	156 Å²	156	149.8 Å²	149.8	83%	0.834	85%	0.845	S	S	*	*	P	Polyproline II helix	trans	-72.1	147.6	165.8	-76.4	-72.6	0	0	0	109.3	P87	P87-N89 PolarHBondContact O-N 3.25Å
90	G	53.4	Low	55.1	Low	82 Å²	82	151.4 Å²	151.4	85%	0.845	85%	0.847	S	S	*	*	P	Polyproline II helix	trans	-60.3	163	-170.5	0	0	0	0	0	116.2
91	D	53.9	Low	55	Low	162 Å²	162	144.9 Å²	144.9	87%	0.866	84%	0.842	S	S	*	*			trans	-114	139.7	170.2	-170.9	-120.9	0	0	0	110.2
92	L	53.9	Low	54.5	Low	168 Å²	168	143.7 Å²	143.7	88%	0.88	84%	0.843	S	S	*	*			trans	-108.5	119.3	-167	-161.4	113.6	0	0	0	107.8
93	G	46.9	Very low	54.5	Low	72 Å²	72	145.8 Å²	145.8	74%	0.742	85%	0.849	S	S	*	*			trans	93.5	124.6	152.2	0	0	0	0	0	118.3
94	H	43.8	Very low	53.7	Low	264 Å²	264	137.7 Å²	137.7	100%	1.222	85%	0.846	S	S	*	*			trans	-139.7	0	132.2	-149.6	156.7	0	0	0	108

Retrieved 94 of 94 residues in 145.6 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).