X5D920_HUMAN Loading...

G protein-coupled receptor 89A isoform B

AlphaFold DB , UniProt , Accession X5D920, Species HUMAN (Homo sapiens, Human), Gene GPR89A, Length 457 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	58.8	Low	88.3	Confident	194 Å²	194	76.8 Å²	76.8	96%	0.956	41%	0.409	S	S	*	.				0	-59.7	0	-66.7	-65.5	-155.8	0	0	111.8	F3 L4 I5	M1-F3 PolarHBondContact O-N 2.91Å; M1-L4 PolarHBondContact O-N 3.24Å; M1-I5 PolarHBondContact O-N 3.01Å
2	S	81.9	Confident	88.9	Confident	52 Å²	52	76.6 Å²	76.6	36%	0.364	41%	0.412	S	S	.	.	H	α-helix	trans	-56.9	-44	-177.8	150.4	0	0	0	0	114.4	L4 I5 D6	S2-L4 VanDerWaalsContact C-N 3.34Å; S2-L4 PolarHBondContact O-N 2.89Å; S2-I5 PolarHBondContact O-N 2.56Å; S2-D6 WeakPolarHBondContact O-CB 3.31Å; S2-D6 PolarHBondContact O-N 3.37Å; S2-D6 PolarHBondContact OG-OD2 3.23Å
3	F	89.4	Confident	89.3	Confident	93 Å²	93	71.5 Å²	71.5	41%	0.408	39%	0.387	S	S	.	.	H	α-helix	trans	-61.6	-36.4	-180	-177.1	-99.9	0	0	0	114.2	M1 S7 F73	M1-F3 PolarHBondContact O-N 2.91Å; F3-S7 VanDerWaalsContact O-CB 3.27Å; F3-S7 WeakPolarHBondContact O-CB 3.46Å; F3-S7 PolarHBondContact O-N 2.95Å; F3-S7 PolarHBondContact O-OG 3.41Å; F3-F73 HydrophobicContact CE2-CB 4.26Å; F3-F73 AromaticContact CE2-CD1 3.75Å; F3-F73 HydrophobicContact CE2-CD1 3.75Å; F3-F73 HydrophobicContact CE2-CE1 4.39Å; F3-F73 HydrophobicContact CE2-CG 4.1Å; F3-F73 AromaticContact CZ-CD1 3.58Å; F3-F73 HydrophobicContact CZ-CD1 3.58Å; F3-F73 AromaticContact CZ-CE1 3.74Å; F3-F73 HydrophobicContact CZ-CE1 3.74Å; F3-F73 HydrophobicContact CZ-CG 4.16Å; F3-F73 HydrophobicContact CZ-CZ 4.44Å
4	L	89.8	Confident	89.8	Confident	126 Å²	126	68.9 Å²	68.9	66%	0.66	37%	0.371	S	S	*	.	H	α-helix	trans	-71.9	-38.4	179.6	-70.2	174.4	0	0	0	111.7	M1 S2 S7 S8	M1-L4 PolarHBondContact O-N 3.24Å; S2-L4 VanDerWaalsContact C-N 3.34Å; S2-L4 PolarHBondContact O-N 2.89Å; L4-S7 PolarHBondContact O-N 3.16Å; L4-S8 WeakPolarHBondContact O-CB 3.35Å; L4-S8 PolarHBondContact O-N 2.64Å
5	I	91.5	Very high	90.2	Very high	102 Å²	102	71.7 Å²	71.7	52%	0.523	38%	0.384	S	S	.	.	H	α-helix	trans	-65.7	-47.2	174.8	-62.8	168.8	0	0	0	109.2	M1 S2 S7 S8 I9	M1-I5 PolarHBondContact O-N 3.01Å; S2-I5 PolarHBondContact O-N 2.56Å; I5-S7 VanDerWaalsContact C-N 3.31Å; I5-S7 PolarHBondContact O-N 3.36Å; I5-S8 WeakPolarHBondContact O-CB 3.38Å; I5-S8 PolarHBondContact O-N 3.06Å; I5-S8 VanDerWaalsContact O-N 3.08Å; I5-I9 HydrophobicContact CG2-CD1 4.2Å; I5-I9 WeakPolarHBondContact O-CG1 3.47Å; I5-I9 PolarHBondContact O-N 3.36Å
6	D	92	Very high	90.5	Very high	13 Å²	13	74.7 Å²	74.7	7%	0.07	40%	0.399	C	S	.	.	H	α-helix	trans	-59.2	-44.3	177.4	-67.6	-3	0	0	0	111.2	S2 S8 I9 M10 L66 N67 S70	S2-D6 WeakPolarHBondContact O-CB 3.31Å; S2-D6 PolarHBondContact O-N 3.37Å; S2-D6 PolarHBondContact OG-OD2 3.23Å; D6-S8 VanDerWaalsContact C-N 3.32Å; D6-S8 PolarHBondContact O-N 2.88Å; D6-I9 PolarHBondContact O-N 3.46Å; D6-M10 WeakPolarHBondContact O-CG 3.25Å; D6-M10 PolarHBondContact O-N 3.49Å; D6-L66 HydrophobicContact CB-CB 4.4Å; D6-L66 HydrophobicContact CB-CD2 3.78Å; D6-N67 WeakPolarHBondContact OD2-CB 3.32Å; D6-N67 PolarHBondContact OD2-N 3.37Å; D6-S70 VanDerWaalsContact CB-OG 3.23Å; D6-S70 WeakPolarHBondContact CB-OG 3.24Å; D6-S70 VanDerWaalsContact OD2-CB 3.26Å; D6-S70 WeakPolarHBondContact OD2-CB 3.24Å; D6-S70 PolarHBondContact OD2-OG 2.92Å
7	S	93	Very high	90.8	Very high	17 Å²	17	73.7 Å²	73.7	12%	0.119	39%	0.39	C	S	.	.	H	α-helix	trans	-63.2	-37.9	175.3	-66.9	0	0	0	0	112.1	F3 L4 I5 M10 I11 H74	F3-S7 VanDerWaalsContact O-CB 3.27Å; F3-S7 WeakPolarHBondContact O-CB 3.46Å; F3-S7 PolarHBondContact O-N 2.95Å; F3-S7 PolarHBondContact O-OG 3.41Å; L4-S7 PolarHBondContact O-N 3.16Å; I5-S7 VanDerWaalsContact C-N 3.31Å; I5-S7 PolarHBondContact O-N 3.36Å; S7-M10 PolarHBondContact O-N 3.11Å; S7-I11 WeakPolarHBondContact O-CB 3.38Å; S7-I11 WeakPolarHBondContact O-CD1 3.35Å; S7-I11 WeakPolarHBondContact O-CG1 3.21Å; S7-I11 PolarHBondContact O-N 3.4Å; S7-H74 PolarHBondContact OG-NE2 3.06Å
8	S	93.3	Very high	91.1	Very high	68 Å²	68	73.2 Å²	73.2	48%	0.476	38%	0.384	S	S	.	.	H	α-helix	trans	-65.8	-39.6	177.1	-179.4	0	0	0	0	111.8	L4 I5 D6 I11 T12	L4-S8 WeakPolarHBondContact O-CB 3.35Å; L4-S8 PolarHBondContact O-N 2.64Å; I5-S8 WeakPolarHBondContact O-CB 3.38Å; I5-S8 PolarHBondContact O-N 3.06Å; I5-S8 VanDerWaalsContact O-N 3.08Å; D6-S8 VanDerWaalsContact C-N 3.32Å; D6-S8 PolarHBondContact O-N 2.88Å; S8-I11 PolarHBondContact O-N 3.2Å; S8-T12 WeakPolarHBondContact O-CB 3.44Å; S8-T12 PolarHBondContact O-N 2.52Å; S8-T12 PolarHBondContact O-OG1 3.24Å
9	I	93.2	Very high	91.2	Very high	73 Å²	73	70.8 Å²	70.8	37%	0.374	38%	0.38	S	S	.	.	H	α-helix	trans	-61.4	-50.8	174.4	-65.8	165.7	0	0	0	109.7	I5 D6 I11 T12 S13 F60 L66	I5-I9 HydrophobicContact CG2-CD1 4.2Å; I5-I9 WeakPolarHBondContact O-CG1 3.47Å; I5-I9 PolarHBondContact O-N 3.36Å; D6-I9 PolarHBondContact O-N 3.46Å; I9-I11 PolarHBondContact O-N 3.05Å; I9-T12 WeakPolarHBondContact O-CB 3.3Å; I9-T12 PolarHBondContact O-N 3.39Å; I9-S13 PolarHBondContact O-N 2.85Å; I9-F60 HydrophobicContact CG2-CZ 4.44Å; I9-L66 HydrophobicContact CB-CD2 4.45Å; I9-L66 HydrophobicContact CD1-CD2 4Å; I9-L66 HydrophobicContact CG2-CD2 4.48Å
10	M	94.1	Very high	91.3	Very high	8 Å²	8	73.1 Å²	73.1	4%	0.039	39%	0.386	C	S	.	.	H	α-helix	trans	-61.4	-39.7	179.2	-69.3	-58.6	-50	0	0	113.2	D6 S7 T12 S13 Q14 T53 L57 F60 L66	D6-M10 WeakPolarHBondContact O-CG 3.25Å; D6-M10 PolarHBondContact O-N 3.49Å; S7-M10 PolarHBondContact O-N 3.11Å; M10-T12 VanDerWaalsContact C-N 3.34Å; M10-S13 PolarHBondContact O-OG 3.01Å; M10-Q14 VanDerWaalsContact O-CB 3.27Å; M10-Q14 WeakPolarHBondContact O-CB 3.16Å; M10-Q14 PolarHBondContact O-N 3.02Å; M10-T53 HydrophobicContact CE-CG2 3.46Å; M10-T53 VanDerWaalsContact CE-CG2 3.46Å; M10-L57 HydrophobicContact CE-CD1 4.46Å; M10-L57 HydrophobicContact CE-CD2 3.57Å; M10-L57 HydrophobicContact CE-CG 3.88Å; M10-L57 HydrophobicContact SD-CD2 3.87Å; M10-F60 HydrophobicContact SD-CD2 3.8Å; M10-F60 HydrophobicContact SD-CE2 3.55Å; M10-F60 VanDerWaalsContact SD-CE2 3.55Å; M10-L66 HydrophobicContact CG-CD1 4.01Å; M10-L66 HydrophobicContact SD-CD1 3.72Å
11	I	94.1	Very high	91.2	Very high	99 Å²	99	69.6 Å²	69.6	51%	0.508	37%	0.368	S	S	.	.	H	α-helix	trans	-68.6	-38.7	177.7	-70.8	165.3	0	0	0	110.3	S7 S8 I9 Q14 I15	S7-I11 WeakPolarHBondContact O-CB 3.38Å; S7-I11 WeakPolarHBondContact O-CD1 3.35Å; S7-I11 WeakPolarHBondContact O-CG1 3.21Å; S7-I11 PolarHBondContact O-N 3.4Å; S8-I11 PolarHBondContact O-N 3.2Å; I9-I11 PolarHBondContact O-N 3.05Å; I11-Q14 PolarHBondContact O-N 3.47Å; I11-I15 HydrophobicContact CG2-CD1 3.8Å; I11-I15 HydrophobicContact CG2-CG1 4.41Å; I11-I15 VanDerWaalsContact O-CG1 3.26Å; I11-I15 WeakPolarHBondContact O-CG1 3.49Å; I11-I15 PolarHBondContact O-N 3.16Å
12	T	95.1	Very high	92.7	Very high	74 Å²	74	63.2 Å²	63.2	45%	0.454	33%	0.333	S	S	.	.	H	α-helix	trans	-63.5	-47	178.5	-57.2	0	0	0	0	110.8	S8 I9 M10 I15 L16	S8-T12 WeakPolarHBondContact O-CB 3.44Å; S8-T12 PolarHBondContact O-N 2.52Å; S8-T12 PolarHBondContact O-OG1 3.24Å; I9-T12 WeakPolarHBondContact O-CB 3.3Å; I9-T12 PolarHBondContact O-N 3.39Å; M10-T12 VanDerWaalsContact C-N 3.34Å; T12-I15 PolarHBondContact O-N 3.46Å; T12-L16 WeakPolarHBondContact O-CG 3.39Å; T12-L16 PolarHBondContact O-N 2.88Å; T12-L16 VanDerWaalsContact O-N 3.09Å
13	S	95.1	Very high	93.1	Very high	11 Å²	11	65 Å²	65	8%	0.077	34%	0.338	C	S	.	.	H	α-helix	trans	-63.9	-41.1	176.2	65.4	0	0	0	0	112.2	I9 M10 I15 L16 F17 E56	I9-S13 PolarHBondContact O-N 2.85Å; M10-S13 PolarHBondContact O-OG 3.01Å; S13-I15 VanDerWaalsContact C-N 3.34Å; S13-I15 PolarHBondContact O-N 3.33Å; S13-L16 WeakPolarHBondContact O-CB 3.21Å; S13-L16 PolarHBondContact O-N 3.12Å; S13-L16 VanDerWaalsContact O-N 3.13Å; S13-F17 WeakPolarHBondContact O-CD2 3.46Å; S13-F17 WeakPolarHBondContact O-CG 3.49Å; S13-F17 PolarHBondContact O-N 2.89Å; S13-E56 VanDerWaalsContact CB-CD 3.44Å; S13-E56 WeakPolarHBondContact CB-OE1 3.47Å; S13-E56 WeakPolarHBondContact CB-OE2 3.36Å; S13-E56 VanDerWaalsContact OG-CD 3.25Å; S13-E56 PolarHBondContact OG-OE1 3Å; S13-E56 PolarHBondContact OG-OE2 2.64Å
14	Q	95.3	Very high	93	Very high	35 Å²	35	61.2 Å²	61.2	16%	0.164	32%	0.321	C	S	.	.	H	α-helix	trans	-58	-43.8	175.2	-170.6	79.2	27.3	0	0	112.1	M10 I11 L16 F17 F18 F50 T53	M10-Q14 VanDerWaalsContact O-CB 3.27Å; M10-Q14 WeakPolarHBondContact O-CB 3.16Å; M10-Q14 PolarHBondContact O-N 3.02Å; I11-Q14 PolarHBondContact O-N 3.47Å; Q14-L16 VanDerWaalsContact C-N 3.34Å; Q14-F17 PolarHBondContact O-N 2.76Å; Q14-F18 WeakPolarHBondContact O-CB 3.31Å; Q14-F18 PolarHBondContact O-N 3.29Å; Q14-F50 VanDerWaalsContact NE2-CD2 3.27Å; Q14-T53 PolarHBondContact OE1-OG1 3.35Å
15	I	96.1	Very high	92.6	Very high	110 Å²	110	55.4 Å²	55.4	56%	0.564	29%	0.291	S	S	*	.	H	α-helix	trans	-64.3	-40.7	177.3	-70.1	166	0	0	0	110.4	I11 T12 S13 F18 G19	I11-I15 HydrophobicContact CG2-CD1 3.8Å; I11-I15 HydrophobicContact CG2-CG1 4.41Å; I11-I15 VanDerWaalsContact O-CG1 3.26Å; I11-I15 WeakPolarHBondContact O-CG1 3.49Å; I11-I15 PolarHBondContact O-N 3.16Å; T12-I15 PolarHBondContact O-N 3.46Å; S13-I15 VanDerWaalsContact C-N 3.34Å; S13-I15 PolarHBondContact O-N 3.33Å; I15-F18 PolarHBondContact O-N 3.06Å; I15-G19 PolarHBondContact O-N 2.93Å
16	L	96	Very high	92.2	Very high	120 Å²	120	53 Å²	53	63%	0.628	28%	0.278	S	S	*	.	H	α-helix	trans	-63.5	-45.7	176	-69.1	174.2	0	0	0	111.7	T12 S13 Q14 F18 G19 F20	T12-L16 WeakPolarHBondContact O-CG 3.39Å; T12-L16 PolarHBondContact O-N 2.88Å; T12-L16 VanDerWaalsContact O-N 3.09Å; S13-L16 WeakPolarHBondContact O-CB 3.21Å; S13-L16 PolarHBondContact O-N 3.12Å; S13-L16 VanDerWaalsContact O-N 3.13Å; Q14-L16 VanDerWaalsContact C-N 3.34Å; L16-F18 VanDerWaalsContact C-N 3.34Å; L16-F18 PolarHBondContact O-N 3.18Å; L16-G19 PolarHBondContact O-N 2.9Å; L16-F20 PolarHBondContact O-N 3.44Å
17	F	95.4	Very high	91.8	Very high	58 Å²	58	61.4 Å²	61.4	25%	0.254	31%	0.309	S	S	.	.	H	α-helix	trans	-64.7	-38.3	176.4	-63.1	-39.4	0	0	0	112.4	S13 Q14 F20 G21 F48 A49 C52 E56	S13-F17 WeakPolarHBondContact O-CD2 3.46Å; S13-F17 WeakPolarHBondContact O-CG 3.49Å; S13-F17 PolarHBondContact O-N 2.89Å; Q14-F17 PolarHBondContact O-N 2.76Å; F17-F20 PolarHBondContact O-N 3.41Å; F17-G21 PolarHBondContact O-N 3.31Å; F17-F48 WeakPolarHBondContact O-CD1 3.48Å; F17-A49 HydrophobicContact CB-CB 4.02Å; F17-C52 HydrophobicContact CB-CB 4.09Å; F17-C52 HydrophobicContact CD1-CB 3.84Å; F17-C52 HydrophobicContact CD2-CB 3.62Å; F17-C52 HydrophobicContact CE1-CB 4.13Å; F17-C52 HydrophobicContact CE2-CB 3.9Å; F17-C52 HydrophobicContact CG-CB 3.59Å; F17-C52 HydrophobicContact CZ-CB 4.16Å; F17-E56 HydrophobicContact CE2-CB 4.06Å; F17-E56 WeakPolarHBondContact CE2-OE2 3.45Å; F17-E56 HydrophobicContact CZ-CB 4.25Å
18	F	95.9	Very high	91.1	Very high	64 Å²	64	64.5 Å²	64.5	28%	0.281	32%	0.321	S	S	.	.	H	α-helix	trans	-61.8	-46.6	173.4	179.6	-92.1	0	0	0	111.3	Q14 I15 L16 F20 G21 W22 S45 V46 A49	Q14-F18 WeakPolarHBondContact O-CB 3.31Å; Q14-F18 PolarHBondContact O-N 3.29Å; I15-F18 PolarHBondContact O-N 3.06Å; L16-F18 VanDerWaalsContact C-N 3.34Å; L16-F18 PolarHBondContact O-N 3.18Å; F18-F20 VanDerWaalsContact C-N 3.33Å; F18-F20 PolarHBondContact O-N 3.42Å; F18-G21 PolarHBondContact O-N 2.93Å; F18-W22 HydrophobicContact CE1-CD2 4.49Å; F18-W22 AromaticContact CE1-CE3 3.79Å; F18-W22 HydrophobicContact CE1-CE3 3.79Å; F18-W22 HydrophobicContact CE1-CZ3 4.37Å; F18-W22 HydrophobicContact CE2-CE3 4.48Å; F18-W22 AromaticContact CZ-CE3 3.57Å; F18-W22 HydrophobicContact CZ-CE3 3.57Å; F18-W22 AromaticContact CZ-CZ3 3.89Å; F18-W22 HydrophobicContact CZ-CZ3 3.89Å; F18-W22 VanDerWaalsContact O-CB 3.3Å; F18-W22 WeakPolarHBondContact O-CB 3.47Å; F18-W22 PolarHBondContact O-N 3.45Å; F18-S45 VanDerWaalsContact CE2-CB 3.47Å; F18-V46 HydrophobicContact CD2-CG2 4.05Å; F18-V46 HydrophobicContact CE2-CG2 3.72Å; F18-A49 HydrophobicContact CB-CB 4.02Å
19	G	93.6	Very high	90.1	Very high	29 Å²	29	61.3 Å²	61.3	30%	0.299	30%	0.299	S	S	.	.	H	α-helix	trans	-59.6	-41.9	175.6	0	0	0	0	0	112.5	I15 L16 W22 L23	I15-G19 PolarHBondContact O-N 2.93Å; L16-G19 PolarHBondContact O-N 2.9Å; G19-W22 WeakPolarHBondContact O-CB 3.43Å; G19-W22 PolarHBondContact O-N 3.02Å; G19-L23 WeakPolarHBondContact O-CB 3.3Å; G19-L23 VanDerWaalsContact O-CG 3.3Å; G19-L23 WeakPolarHBondContact O-CG 3.31Å; G19-L23 PolarHBondContact O-N 3.48Å
20	F	92.1	Very high	89.1	Confident	115 Å²	115	58.2 Å²	58.2	50%	0.504	28%	0.283	S	S	.	.	H	α-helix	trans	-64.7	-46.6	174.9	-175.7	-90.3	0	0	0	112.1	L16 F17 F18 W22 L23 F24 F48 L362	L16-F20 PolarHBondContact O-N 3.44Å; F17-F20 PolarHBondContact O-N 3.41Å; F18-F20 VanDerWaalsContact C-N 3.33Å; F18-F20 PolarHBondContact O-N 3.42Å; F20-W22 VanDerWaalsContact C-N 3.28Å; F20-W22 PolarHBondContact O-N 2.9Å; F20-L23 PolarHBondContact O-N 3.2Å; F20-F24 WeakPolarHBondContact O-CB 3.48Å; F20-F24 PolarHBondContact O-N 2.91Å; F20-F48 AromaticContact CD1-CE1 3.49Å; F20-F48 HydrophobicContact CD1-CE1 3.49Å; F20-F48 VanDerWaalsContact CD1-CE1 3.49Å; F20-F48 AromaticContact CD1-CZ 3.59Å; F20-F48 HydrophobicContact CD1-CZ 3.59Å; F20-F48 HydrophobicContact CE1-CE1 4.21Å; F20-F48 AromaticContact CE1-CZ 3.83Å; F20-F48 HydrophobicContact CE1-CZ 3.83Å; F20-F48 HydrophobicContact CG-CE1 4.45Å; F20-L362 HydrophobicContact CE1-CD1 4.45Å
21	G	88.8	Confident	87.8	Confident	0 Å²	0	65 Å²	65	0%	0	31%	0.312	C	S	.	.	H	α-helix	trans	-59.4	-39.8	176	0	0	0	0	0	112.3	F17 F18 F24 F25	F17-G21 PolarHBondContact O-N 3.31Å; F18-G21 PolarHBondContact O-N 2.93Å; G21-F24 PolarHBondContact O-N 3.42Å; G21-F25 WeakPolarHBondContact O-CB 3.28Å; G21-F25 PolarHBondContact O-N 2.98Å
22	W	91.8	Very high	86.4	Confident	61 Å²	61	66 Å²	66	23%	0.231	32%	0.318	C	S	.	.	H	α-helix	trans	-63.2	-46.2	175.1	-171.3	-81.6	0	0	0	112.5	F18 G19 F20 F25 M26 Y38 Q41 V42 S45	F18-W22 HydrophobicContact CE1-CD2 4.49Å; F18-W22 AromaticContact CE1-CE3 3.79Å; F18-W22 HydrophobicContact CE1-CE3 3.79Å; F18-W22 HydrophobicContact CE1-CZ3 4.37Å; F18-W22 HydrophobicContact CE2-CE3 4.48Å; F18-W22 AromaticContact CZ-CE3 3.57Å; F18-W22 HydrophobicContact CZ-CE3 3.57Å; F18-W22 AromaticContact CZ-CZ3 3.89Å; F18-W22 HydrophobicContact CZ-CZ3 3.89Å; F18-W22 VanDerWaalsContact O-CB 3.3Å; F18-W22 WeakPolarHBondContact O-CB 3.47Å; F18-W22 PolarHBondContact O-N 3.45Å; G19-W22 WeakPolarHBondContact O-CB 3.43Å; G19-W22 PolarHBondContact O-N 3.02Å; F20-W22 VanDerWaalsContact C-N 3.28Å; F20-W22 PolarHBondContact O-N 2.9Å; W22-F25 PolarHBondContact O-N 3.37Å; W22-M26 WeakPolarHBondContact O-CB 3.38Å; W22-M26 PolarHBondContact O-N 3.39Å; W22-Y38 AromaticContact CH2-CD2 3.88Å; W22-Y38 HydrophobicContact CH2-CD2 3.88Å; W22-Y38 AromaticContact CH2-CE2 3.37Å; W22-Y38 HydrophobicContact CH2-CE2 3.37Å; W22-Y38 AromaticContact CH2-CZ 3.94Å; W22-Y38 HydrophobicContact CZ2-CE2 4.07Å; W22-Y38 HydrophobicContact CZ3-CE2 4.35Å; W22-Q41 HydrophobicContact CD2-CG 4.08Å; W22-Q41 VanDerWaalsContact CE2-CD 3.48Å; W22-Q41 HydrophobicContact CE3-CG 3.75Å; W22-Q41 HydrophobicContact CH2-CG 3.77Å; W22-Q41 HydrophobicContact CZ2-CG 4.17Å; W22-Q41 HydrophobicContact CZ3-CB 4.43Å; W22-Q41 HydrophobicContact CZ3-CG 3.59Å; W22-Q41 VanDerWaalsContact NE1-NE2 3.18Å; W22-V42 HydrophobicContact CH2-CG2 4.34Å; W22-V42 HydrophobicContact CZ3-CG2 3.84Å; W22-S45 WeakPolarHBondContact CA-OG 3.33Å; W22-S45 PolarHBondContact N-OG 3.34Å
23	L	89.3	Confident	85	Confident	88 Å²	88	64.7 Å²	64.7	46%	0.461	31%	0.305	S	S	.	.	H	α-helix	trans	-65.7	-43.3	177.4	-74.9	173.4	0	0	0	111.8	G19 F20 F25 M26 R27	G19-L23 WeakPolarHBondContact O-CB 3.3Å; G19-L23 VanDerWaalsContact O-CG 3.3Å; G19-L23 WeakPolarHBondContact O-CG 3.31Å; G19-L23 PolarHBondContact O-N 3.48Å; F20-L23 PolarHBondContact O-N 3.2Å; L23-F25 VanDerWaalsContact C-N 3.33Å; L23-F25 PolarHBondContact O-N 2.87Å; L23-M26 PolarHBondContact O-N 3.45Å; L23-R27 WeakPolarHBondContact O-CB 3.4Å; L23-R27 WeakPolarHBondContact O-CG 3.39Å; L23-R27 PolarHBondContact O-N 3.32Å
24	F	86.6	Confident	83.2	Confident	14 Å²	14	73.3 Å²	73.3	6%	0.061	35%	0.345	C	S	.	.	H	α-helix	trans	-58.6	-47	175.3	175.8	-95.4	0	0	0	110.8	F20 G21 M26 Q28 L29 F44 L362 T366	F20-F24 WeakPolarHBondContact O-CB 3.48Å; F20-F24 PolarHBondContact O-N 2.91Å; G21-F24 PolarHBondContact O-N 3.42Å; F24-M26 PolarHBondContact O-N 3.36Å; F24-Q28 HydrophobicContact CD2-CB 4.16Å; F24-Q28 HydrophobicContact CE2-CB 4.15Å; F24-Q28 HydrophobicContact CE2-CG 4.21Å; F24-Q28 WeakPolarHBondContact O-CA 3.44Å; F24-Q28 WeakPolarHBondContact O-CB 3.4Å; F24-Q28 PolarHBondContact O-N 2.95Å; F24-L29 HydrophobicContact CD1-CD1 3.94Å; F24-L29 HydrophobicContact CE1-CD1 3.28Å; F24-L29 HydrophobicContact CZ-CD1 3.96Å; F24-L29 PolarHBondContact O-N 2.85Å; F24-F44 AromaticContact CD1-CE1 3.95Å; F24-F44 HydrophobicContact CD1-CE1 3.95Å; F24-F44 AromaticContact CD1-CZ 3.98Å; F24-F44 HydrophobicContact CD1-CZ 3.98Å; F24-F44 HydrophobicContact CE1-CE1 4.42Å; F24-F44 AromaticContact CE1-CZ 3.99Å; F24-F44 HydrophobicContact CE1-CZ 3.99Å; F24-L362 HydrophobicContact CD1-CD2 4.22Å; F24-L362 HydrophobicContact CD2-CD1 4.31Å; F24-L362 HydrophobicContact CE1-CD2 3.67Å; F24-L362 HydrophobicContact CE2-CB 3.92Å; F24-L362 HydrophobicContact CE2-CD1 4.1Å; F24-L362 HydrophobicContact CE2-CD2 4.14Å; F24-L362 HydrophobicContact CE2-CG 4.27Å; F24-L362 HydrophobicContact CZ-CB 3.83Å; F24-L362 HydrophobicContact CZ-CD1 4.44Å; F24-L362 HydrophobicContact CZ-CD2 3.64Å; F24-L362 HydrophobicContact CZ-CG 4.16Å; F24-T366 WeakPolarHBondContact CZ-OG1 3.48Å
25	F	83.4	Confident	81.4	Confident	4 Å²	4	77.7 Å²	77.7	2%	0.018	37%	0.368	C	S	.	.	I	π-helix	trans	-57.3	-49.7	176.4	-177.9	-94.8	0	0	0	112.3	G21 W22 L23 L29 F30 Q41 F44 V382	G21-F25 WeakPolarHBondContact O-CB 3.28Å; G21-F25 PolarHBondContact O-N 2.98Å; W22-F25 PolarHBondContact O-N 3.37Å; L23-F25 VanDerWaalsContact C-N 3.33Å; L23-F25 PolarHBondContact O-N 2.87Å; F25-L29 HydrophobicContact CD2-CB 4.38Å; F25-L29 PolarHBondContact O-N 3.45Å; F25-F30 HydrophobicContact CD1-CD2 4.3Å; F25-F30 HydrophobicContact CD2-CD2 4.21Å; F25-F30 HydrophobicContact CE1-CB 4.35Å; F25-F30 AromaticContact CE1-CD2 3.57Å; F25-F30 HydrophobicContact CE1-CD2 3.57Å; F25-F30 HydrophobicContact CE1-CE2 4.01Å; F25-F30 HydrophobicContact CE1-CG 4.06Å; F25-F30 AromaticContact CE2-CD2 3.39Å; F25-F30 HydrophobicContact CE2-CD2 3.39Å; F25-F30 AromaticContact CE2-CE2 3.39Å; F25-F30 HydrophobicContact CE2-CE2 3.39Å; F25-F30 AromaticContact CZ-CD2 3.07Å; F25-F30 HydrophobicContact CZ-CD2 3.07Å; F25-F30 AromaticContact CZ-CE2 3.09Å; F25-F30 HydrophobicContact CZ-CE2 3.09Å; F25-F30 AromaticContact CZ-CG 3.96Å; F25-F30 HydrophobicContact CZ-CG 3.96Å; F25-F30 HydrophobicContact CZ-CZ 4.05Å; F25-F30 PolarHBondContact O-N 3.35Å; F25-Q41 HydrophobicContact CD1-CB 3.92Å; F25-Q41 HydrophobicContact CD1-CG 3.45Å; F25-Q41 VanDerWaalsContact CD1-CG 3.45Å; F25-Q41 HydrophobicContact CE1-CB 3.55Å; F25-Q41 HydrophobicContact CE1-CG 3.63Å; F25-Q41 HydrophobicContact CG-CG 4.12Å; F25-Q41 HydrophobicContact CZ-CB 4.02Å; F25-Q41 HydrophobicContact CZ-CG 4.45Å; F25-F44 HydrophobicContact CB-CD1 4.06Å; F25-F44 HydrophobicContact CB-CE1 4.27Å; F25-F44 HydrophobicContact CD2-CB 4.31Å; F25-F44 AromaticContact CD2-CD1 3.85Å; F25-F44 HydrophobicContact CD2-CD1 3.85Å; F25-F44 HydrophobicContact CD2-CE1 4.38Å; F25-F44 AromaticContact CD2-CG 4Å; F25-F44 HydrophobicContact CD2-CG 4Å; F25-F44 HydrophobicContact CG-CD1 4.35Å; F25-V382 HydrophobicContact CD2-CG1 4.3Å; F25-V382 HydrophobicContact CE2-CB 4.4Å; F25-V382 HydrophobicContact CE2-CG1 3.49Å; F25-V382 VanDerWaalsContact CE2-CG1 3.49Å; F25-V382 HydrophobicContact CE2-CG2 4.15Å; F25-V382 HydrophobicContact CZ-CG1 4.35Å
26	M	82.8	Confident	79.9	Confident	51 Å²	51	80 Å²	80	25%	0.251	37%	0.369	S	S	.	.	I	π-helix	trans	-67.9	-43.4	-177.6	-81.8	-73.9	175.6	0	0	113.3	W22 L23 F24 Q41	W22-M26 WeakPolarHBondContact O-CB 3.38Å; W22-M26 PolarHBondContact O-N 3.39Å; L23-M26 PolarHBondContact O-N 3.45Å; F24-M26 PolarHBondContact O-N 3.36Å; M26-Q41 VanDerWaalsContact CE-CD 3.43Å; M26-Q41 VanDerWaalsContact CG-NE2 3.33Å
27	R	82.7	Confident	79.2	Confident	190 Å²	190	78.5 Å²	78.5	72%	0.717	36%	0.359	S	S	*	.	I	π-helix	trans	-86.5	-27.3	-173.3	-68.7	-173.5	174	-177.9	-0.7	113.4	L23	L23-R27 WeakPolarHBondContact O-CB 3.4Å; L23-R27 WeakPolarHBondContact O-CG 3.39Å; L23-R27 PolarHBondContact O-N 3.32Å
28	Q	78.5	Confident	78.8	Confident	82 Å²	82	83.2 Å²	83.2	38%	0.383	38%	0.376	S	S	.	.	I	π-helix	trans	-123.3	-26.2	-165.3	-149.6	167.6	-4.2	0	0	114.7	F24 T366 Y370	F24-Q28 HydrophobicContact CD2-CB 4.16Å; F24-Q28 HydrophobicContact CE2-CB 4.15Å; F24-Q28 HydrophobicContact CE2-CG 4.21Å; F24-Q28 WeakPolarHBondContact O-CA 3.44Å; F24-Q28 WeakPolarHBondContact O-CB 3.4Å; F24-Q28 PolarHBondContact O-N 2.95Å; Q28-T366 HydrophobicContact CG-CG2 4.08Å; Q28-Y370 PolarHBondContact O-OH 2.65Å
29	L	72.9	Confident	78.6	Confident	1 Å²	1	82.8 Å²	82.8	1%	0.005	38%	0.379	C	S	.	.	I	π-helix	trans	-94.8	-52.4	169.6	-93.8	92.4	0	0	0	111.6	F24 F25 F44 F369 V382 L385	F24-L29 HydrophobicContact CD1-CD1 3.94Å; F24-L29 HydrophobicContact CE1-CD1 3.28Å; F24-L29 HydrophobicContact CZ-CD1 3.96Å; F24-L29 PolarHBondContact O-N 2.85Å; F25-L29 HydrophobicContact CD2-CB 4.38Å; F25-L29 PolarHBondContact O-N 3.45Å; L29-F44 HydrophobicContact CD1-CZ 4.47Å; L29-F369 HydrophobicContact CB-CD1 4.46Å; L29-F369 HydrophobicContact CB-CE1 4.43Å; L29-F369 HydrophobicContact CD2-CB 4.42Å; L29-F369 HydrophobicContact CD2-CD1 4.47Å; L29-F369 HydrophobicContact CD2-CD2 3.72Å; L29-F369 HydrophobicContact CD2-CE2 4.1Å; L29-F369 HydrophobicContact CD2-CG 3.93Å; L29-F369 HydrophobicContact CG-CB 4.47Å; L29-F369 HydrophobicContact CG-CD1 4.22Å; L29-F369 HydrophobicContact CG-CD2 4.34Å; L29-F369 HydrophobicContact CG-CG 4.06Å; L29-F369 WeakPolarHBondContact O-CE1 3.45Å; L29-V382 HydrophobicContact CD2-CG2 3.56Å; L29-L385 HydrophobicContact CD2-CD1 3.93Å
30	F	71.7	Confident	78.4	Confident	8 Å²	8	81.4 Å²	81.4	4%	0.035	37%	0.365	C	S	.	.	S	Bend	trans	-99.3	19.3	-168.6	-92.5	-96.4	0	0	0	115.4	F25 D32 Y33 F369 V382	F25-F30 HydrophobicContact CD1-CD2 4.3Å; F25-F30 HydrophobicContact CD2-CD2 4.21Å; F25-F30 HydrophobicContact CE1-CB 4.35Å; F25-F30 AromaticContact CE1-CD2 3.57Å; F25-F30 HydrophobicContact CE1-CD2 3.57Å; F25-F30 HydrophobicContact CE1-CE2 4.01Å; F25-F30 HydrophobicContact CE1-CG 4.06Å; F25-F30 AromaticContact CE2-CD2 3.39Å; F25-F30 HydrophobicContact CE2-CD2 3.39Å; F25-F30 AromaticContact CE2-CE2 3.39Å; F25-F30 HydrophobicContact CE2-CE2 3.39Å; F25-F30 AromaticContact CZ-CD2 3.07Å; F25-F30 HydrophobicContact CZ-CD2 3.07Å; F25-F30 AromaticContact CZ-CE2 3.09Å; F25-F30 HydrophobicContact CZ-CE2 3.09Å; F25-F30 AromaticContact CZ-CG 3.96Å; F25-F30 HydrophobicContact CZ-CG 3.96Å; F25-F30 HydrophobicContact CZ-CZ 4.05Å; F25-F30 PolarHBondContact O-N 3.35Å; F30-D32 PolarHBondContact O-N 2.94Å; F30-Y33 VanDerWaalsContact CD1-CB 3.43Å; F30-Y33 HydrophobicContact CD1-CD2 4.47Å; F30-Y33 HydrophobicContact CD1-CG 4.25Å; F30-Y33 HydrophobicContact CE1-CG 4.38Å; F30-Y33 PolarHBondContact O-N 3.15Å; F30-F369 HydrophobicContact CE2-CZ 4.48Å; F30-V382 HydrophobicContact CD2-CG2 4.27Å; F30-V382 HydrophobicContact CE2-CB 4.31Å; F30-V382 HydrophobicContact CE2-CG2 3.35Å; F30-V382 HydrophobicContact CZ-CG2 4.04Å
31	K	67.6	Low	78.3	Confident	152 Å²	152	76.2 Å²	76.2	66%	0.661	34%	0.342	S	S	*	.	T	Hydrogen-bonded Turn	trans	-52.2	-36.7	-175.3	-168.7	-178.4	174.3	-170	0	113.2
32	D	63.8	Low	78.6	Confident	119 Å²	119	78.1 Å²	78.1	64%	0.636	35%	0.354	S	S	*	.	T	Hydrogen-bonded Turn	trans	-113.6	12.1	-171.9	-50.3	-53	0	0	0	113.9	F30	F30-D32 PolarHBondContact O-N 2.94Å
33	Y	66.1	Low	78.7	Confident	46 Å²	46	76.2 Å²	76.2	18%	0.18	35%	0.348	C	S	.	.			trans	-113.9	118.2	-176.4	-75.8	-75.5	0	0	0	112.2	F30 F369 S373	F30-Y33 VanDerWaalsContact CD1-CB 3.43Å; F30-Y33 HydrophobicContact CD1-CD2 4.47Å; F30-Y33 HydrophobicContact CD1-CG 4.25Å; F30-Y33 HydrophobicContact CE1-CG 4.38Å; F30-Y33 PolarHBondContact O-N 3.15Å; Y33-F369 HydrophobicContact CD2-CE1 4.09Å; Y33-F369 HydrophobicContact CD2-CZ 4.02Å; Y33-F369 AromaticContact CE2-CE1 3.66Å; Y33-F369 HydrophobicContact CE2-CE1 3.66Å; Y33-F369 AromaticContact CE2-CZ 3.75Å; Y33-F369 HydrophobicContact CE2-CZ 3.75Å; Y33-S373 VanDerWaalsContact OH-C 3.23Å; Y33-S373 WeakPolarHBondContact OH-CB 3.36Å; Y33-S373 PolarHBondContact OH-O 3.49Å; Y33-S373 PolarHBondContact OH-OG 2.98Å
34	E	55.8	Low	78.8	Confident	193 Å²	193	72 Å²	72	90%	0.902	33%	0.326	S	S	*	.	S	Bend	trans	-74.7	-29.6	-172.8	-63.3	-178.1	158.4	0	0	114.3	R36	E34-R36 PolarHBondContact O-N 2.95Å
35	I	58.4	Low	79.2	Confident	127 Å²	127	71.4 Å²	71.4	65%	0.651	32%	0.323	S	S	*	.			trans	-95.3	95.8	-175.6	-54.2	172.9	0	0	0	109.6
36	R	64.3	Low	79.8	Confident	158 Å²	158	73 Å²	73	60%	0.596	33%	0.333	S	S	*	.			trans	-95.2	112.8	178.6	-66.6	-175.6	-68.6	-139.9	-4.8	111.2	E34	E34-R36 PolarHBondContact O-N 2.95Å
37	Q	82.1	Confident	80.4	Confident	89 Å²	89	70.5 Å²	70.5	42%	0.416	32%	0.321	S	S	.	.			trans	-90.2	111.4	171.1	-157	73.5	-15.8	0	0	110.1	V39 V40 Q41 F97	Q37-V39 PolarHBondContact O-N 2.87Å; Q37-V40 HydrophobicContact CB-CG2 4.13Å; Q37-V40 HydrophobicContact CG-CG2 4.48Å; Q37-V40 PolarHBondContact O-N 3.4Å; Q37-V40 VanDerWaalsContact O-N 3.13Å; Q37-Q41 PolarHBondContact O-N 2.97Å; Q37-F97 HydrophobicContact CG-CE1 3.99Å; Q37-F97 HydrophobicContact CG-CZ 3.81Å
38	Y	87	Confident	80.9	Confident	156 Å²	156	61.7 Å²	61.7	61%	0.612	29%	0.287	S	S	*	.	H	α-helix	trans	-54.7	-38.6	-175.6	-174.9	-96	0	0	0	113.3	W22 V40 Q41 V42	W22-Y38 AromaticContact CH2-CD2 3.88Å; W22-Y38 HydrophobicContact CH2-CD2 3.88Å; W22-Y38 AromaticContact CH2-CE2 3.37Å; W22-Y38 HydrophobicContact CH2-CE2 3.37Å; W22-Y38 AromaticContact CH2-CZ 3.94Å; W22-Y38 HydrophobicContact CZ2-CE2 4.07Å; W22-Y38 HydrophobicContact CZ3-CE2 4.35Å; Y38-V40 PolarHBondContact O-N 3.31Å; Y38-Q41 WeakPolarHBondContact O-CB 3.3Å; Y38-Q41 PolarHBondContact O-N 3.1Å; Y38-V42 HydrophobicContact CD1-CG2 3.76Å; Y38-V42 HydrophobicContact CE1-CG2 3.35Å; Y38-V42 HydrophobicContact CE2-CG2 4.44Å; Y38-V42 HydrophobicContact CG-CG2 4.44Å; Y38-V42 WeakPolarHBondContact O-CG2 3.45Å; Y38-V42 PolarHBondContact O-N 3.11Å
39	V	90.9	Very high	81.8	Confident	56 Å²	56	57.8 Å²	57.8	34%	0.339	27%	0.269	S	S	.	.	H	α-helix	trans	-59.9	-43.9	-179.8	178.7	0	0	0	0	112	Q37 Q41 V42 I43 Y93	Q37-V39 PolarHBondContact O-N 2.87Å; V39-Q41 VanDerWaalsContact C-N 3.31Å; V39-Q41 PolarHBondContact O-N 3.45Å; V39-V42 PolarHBondContact O-N 3.02Å; V39-I43 HydrophobicContact CG1-CD1 3.73Å; V39-I43 HydrophobicContact CG1-CG1 4.44Å; V39-I43 VanDerWaalsContact O-CG1 3.26Å; V39-I43 WeakPolarHBondContact O-CG1 3.47Å; V39-I43 PolarHBondContact O-N 3.02Å; V39-Y93 HydrophobicContact CG1-CD1 4.1Å; V39-Y93 HydrophobicContact CG1-CE1 3.64Å
40	V	90.7	Very high	82.9	Confident	0 Å²	0	59.3 Å²	59.3	0%	0	28%	0.276	C	S	.	.	H	α-helix	trans	-64.4	-41.2	-179	174.3	0	0	0	0	110.5	Q37 Y38 I43 F44 F97 N379 V382 L383	Q37-V40 HydrophobicContact CB-CG2 4.13Å; Q37-V40 HydrophobicContact CG-CG2 4.48Å; Q37-V40 PolarHBondContact O-N 3.4Å; Q37-V40 VanDerWaalsContact O-N 3.13Å; Y38-V40 PolarHBondContact O-N 3.31Å; V40-I43 PolarHBondContact O-N 2.82Å; V40-F44 WeakPolarHBondContact O-CB 3.44Å; V40-F44 PolarHBondContact O-N 3.47Å; V40-F97 HydrophobicContact CG2-CD2 4.16Å; V40-F97 HydrophobicContact CG2-CE1 4.41Å; V40-F97 HydrophobicContact CG2-CE2 3.43Å; V40-F97 VanDerWaalsContact CG2-CE2 3.43Å; V40-F97 HydrophobicContact CG2-CZ 3.6Å; V40-N379 HydrophobicContact CG2-CB 4.18Å; V40-V382 HydrophobicContact CG1-CB 3.98Å; V40-V382 HydrophobicContact CG1-CG1 3.48Å; V40-V382 VanDerWaalsContact CG1-CG1 3.48Å; V40-L383 HydrophobicContact CG1-CD2 4.12Å; V40-L383 HydrophobicContact CG1-CG 4.04Å; V40-L383 HydrophobicContact CG2-CD1 4.23Å; V40-L383 HydrophobicContact CG2-CD2 4.49Å; V40-L383 HydrophobicContact CG2-CG 4.33Å
41	Q	90.2	Very high	83.9	Confident	6 Å²	6	59 Å²	59	3%	0.028	27%	0.274	C	S	.	.	H	α-helix	trans	-64.5	-45.2	177.7	179.3	174.2	16.8	0	0	112.6	W22 F25 M26 Q37 Y38 V39 F44 S45	W22-Q41 HydrophobicContact CD2-CG 4.08Å; W22-Q41 VanDerWaalsContact CE2-CD 3.48Å; W22-Q41 HydrophobicContact CE3-CG 3.75Å; W22-Q41 HydrophobicContact CH2-CG 3.77Å; W22-Q41 HydrophobicContact CZ2-CG 4.17Å; W22-Q41 HydrophobicContact CZ3-CB 4.43Å; W22-Q41 HydrophobicContact CZ3-CG 3.59Å; W22-Q41 VanDerWaalsContact NE1-NE2 3.18Å; F25-Q41 HydrophobicContact CD1-CB 3.92Å; F25-Q41 HydrophobicContact CD1-CG 3.45Å; F25-Q41 VanDerWaalsContact CD1-CG 3.45Å; F25-Q41 HydrophobicContact CE1-CB 3.55Å; F25-Q41 HydrophobicContact CE1-CG 3.63Å; F25-Q41 HydrophobicContact CG-CG 4.12Å; F25-Q41 HydrophobicContact CZ-CB 4.02Å; F25-Q41 HydrophobicContact CZ-CG 4.45Å; M26-Q41 VanDerWaalsContact CE-CD 3.43Å; M26-Q41 VanDerWaalsContact CG-NE2 3.33Å; Q37-Q41 PolarHBondContact O-N 2.97Å; Y38-Q41 WeakPolarHBondContact O-CB 3.3Å; Y38-Q41 PolarHBondContact O-N 3.1Å; V39-Q41 VanDerWaalsContact C-N 3.31Å; V39-Q41 PolarHBondContact O-N 3.45Å; Q41-F44 PolarHBondContact O-N 2.96Å; Q41-S45 WeakPolarHBondContact O-CB 3.36Å; Q41-S45 PolarHBondContact O-N 3.42Å; Q41-S45 PolarHBondContact O-OG 3Å
42	V	93.1	Very high	85.1	Confident	40 Å²	40	52 Å²	52	24%	0.242	25%	0.245	C	C	.	.	H	α-helix	trans	-61.1	-49.6	176.8	172.3	0	0	0	0	109.7	W22 Y38 V39 F44 S45 V46	W22-V42 HydrophobicContact CH2-CG2 4.34Å; W22-V42 HydrophobicContact CZ3-CG2 3.84Å; Y38-V42 HydrophobicContact CD1-CG2 3.76Å; Y38-V42 HydrophobicContact CE1-CG2 3.35Å; Y38-V42 HydrophobicContact CE2-CG2 4.44Å; Y38-V42 HydrophobicContact CG-CG2 4.44Å; Y38-V42 WeakPolarHBondContact O-CG2 3.45Å; Y38-V42 PolarHBondContact O-N 3.11Å; V39-V42 PolarHBondContact O-N 3.02Å; V42-F44 PolarHBondContact O-N 3.2Å; V42-S45 PolarHBondContact O-N 2.93Å; V42-V46 HydrophobicContact CG1-CG2 3.98Å; V42-V46 WeakPolarHBondContact O-CB 3.43Å; V42-V46 VanDerWaalsContact O-CG2 3.26Å; V42-V46 WeakPolarHBondContact O-CG2 3.48Å; V42-V46 PolarHBondContact O-N 3.23Å
43	I	94.1	Very high	86.6	Confident	20 Å²	20	46.5 Å²	46.5	10%	0.103	22%	0.216	C	C	.	.	H	α-helix	trans	-56.9	-50.2	179.9	-68.9	166.6	0	0	0	110.5	V39 V40 S45 V46 T47 V90 Y93 L383	V39-I43 HydrophobicContact CG1-CD1 3.73Å; V39-I43 HydrophobicContact CG1-CG1 4.44Å; V39-I43 VanDerWaalsContact O-CG1 3.26Å; V39-I43 WeakPolarHBondContact O-CG1 3.47Å; V39-I43 PolarHBondContact O-N 3.02Å; V40-I43 PolarHBondContact O-N 2.82Å; I43-S45 PolarHBondContact O-N 3.47Å; I43-V46 PolarHBondContact O-N 3.14Å; I43-T47 WeakPolarHBondContact O-CB 3.46Å; I43-T47 PolarHBondContact O-N 3.38Å; I43-T47 PolarHBondContact O-OG1 3.33Å; I43-V90 HydrophobicContact CG2-CG2 3.58Å; I43-Y93 HydrophobicContact CD1-CD1 4.25Å; I43-Y93 HydrophobicContact CD1-CD2 3.24Å; I43-Y93 HydrophobicContact CD1-CE2 3.59Å; I43-Y93 HydrophobicContact CD1-CG 3.61Å; I43-Y93 HydrophobicContact CG1-CD2 4.49Å; I43-L383 HydrophobicContact CB-CD2 4.21Å; I43-L383 HydrophobicContact CD1-CD2 4.2Å; I43-L383 HydrophobicContact CG2-CD2 3.87Å
44	F	93.3	Very high	87.8	Confident	1 Å²	1	44.4 Å²	44.4	0%	0.004	21%	0.207	C	C	.	.	H	α-helix	trans	-57.4	-47.5	178	179.3	-86.1	0	0	0	112.1	F24 F25 L29 V40 Q41 V42 T47 F48 V382 A386 M389	F24-F44 AromaticContact CD1-CE1 3.95Å; F24-F44 HydrophobicContact CD1-CE1 3.95Å; F24-F44 AromaticContact CD1-CZ 3.98Å; F24-F44 HydrophobicContact CD1-CZ 3.98Å; F24-F44 HydrophobicContact CE1-CE1 4.42Å; F24-F44 AromaticContact CE1-CZ 3.99Å; F24-F44 HydrophobicContact CE1-CZ 3.99Å; F25-F44 HydrophobicContact CB-CD1 4.06Å; F25-F44 HydrophobicContact CB-CE1 4.27Å; F25-F44 HydrophobicContact CD2-CB 4.31Å; F25-F44 AromaticContact CD2-CD1 3.85Å; F25-F44 HydrophobicContact CD2-CD1 3.85Å; F25-F44 HydrophobicContact CD2-CE1 4.38Å; F25-F44 AromaticContact CD2-CG 4Å; F25-F44 HydrophobicContact CD2-CG 4Å; F25-F44 HydrophobicContact CG-CD1 4.35Å; L29-F44 HydrophobicContact CD1-CZ 4.47Å; V40-F44 WeakPolarHBondContact O-CB 3.44Å; V40-F44 PolarHBondContact O-N 3.47Å; Q41-F44 PolarHBondContact O-N 2.96Å; V42-F44 PolarHBondContact O-N 3.2Å; F44-T47 PolarHBondContact O-N 3.46Å; F44-F48 WeakPolarHBondContact O-CB 3.46Å; F44-F48 PolarHBondContact O-N 3.42Å; F44-V382 HydrophobicContact CB-CG1 4.29Å; F44-V382 HydrophobicContact CD2-CG1 4.09Å; F44-V382 HydrophobicContact CG-CG1 4.43Å; F44-A386 HydrophobicContact CB-CB 4.49Å; F44-A386 HydrophobicContact CD2-CB 3.9Å; F44-M389 HydrophobicContact CD2-CE 4.46Å; F44-M389 HydrophobicContact CE2-CE 4.11Å; F44-M389 HydrophobicContact CE2-SD 4.23Å; F44-M389 HydrophobicContact CZ-CE 4.26Å; F44-M389 HydrophobicContact CZ-SD 4.12Å
45	S	94.1	Very high	89.4	Confident	0 Å²	0	35.3 Å²	35.3	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-69.3	-37.2	-176.5	-52.6	0	0	0	0	112.1	F18 W22 Q41 V42 I43 A49	F18-S45 VanDerWaalsContact CE2-CB 3.47Å; W22-S45 WeakPolarHBondContact CA-OG 3.33Å; W22-S45 PolarHBondContact N-OG 3.34Å; Q41-S45 WeakPolarHBondContact O-CB 3.36Å; Q41-S45 PolarHBondContact O-N 3.42Å; Q41-S45 PolarHBondContact O-OG 3Å; V42-S45 PolarHBondContact O-N 2.93Å; I43-S45 PolarHBondContact O-N 3.47Å; S45-A49 WeakPolarHBondContact O-CB 3.41Å; S45-A49 PolarHBondContact O-N 2.82Å
46	V	95.7	Very high	91	Very high	37 Å²	37	30.6 Å²	30.6	22%	0.224	14%	0.14	C	C	.	.	H	α-helix	trans	-65.7	-48.4	173.2	174.5	0	0	0	0	110.1	F18 V42 I43 F48 A49 F50 I85	F18-V46 HydrophobicContact CD2-CG2 4.05Å; F18-V46 HydrophobicContact CE2-CG2 3.72Å; V42-V46 HydrophobicContact CG1-CG2 3.98Å; V42-V46 WeakPolarHBondContact O-CB 3.43Å; V42-V46 VanDerWaalsContact O-CG2 3.26Å; V42-V46 WeakPolarHBondContact O-CG2 3.48Å; V42-V46 PolarHBondContact O-N 3.23Å; I43-V46 PolarHBondContact O-N 3.14Å; V46-F48 VanDerWaalsContact C-N 3.29Å; V46-F48 PolarHBondContact O-N 2.9Å; V46-A49 PolarHBondContact O-N 3.43Å; V46-F50 HydrophobicContact CG1-CD2 3.54Å; V46-F50 HydrophobicContact CG1-CE2 3.67Å; V46-F50 WeakPolarHBondContact O-CD2 3.42Å; V46-F50 PolarHBondContact O-N 3.3Å; V46-I85 HydrophobicContact CG1-CD1 3.56Å
47	T	95.4	Very high	92.3	Very high	0 Å²	0	23.1 Å²	23.1	0%	0	11%	0.112	C	C	.	.	H	α-helix	trans	-57.3	-44.2	176.7	-56.2	0	0	0	0	111.1	I43 F44 S51 I82 I85 L86 M389	I43-T47 WeakPolarHBondContact O-CB 3.46Å; I43-T47 PolarHBondContact O-N 3.38Å; I43-T47 PolarHBondContact O-OG1 3.33Å; F44-T47 PolarHBondContact O-N 3.46Å; T47-S51 VanDerWaalsContact O-CB 3.32Å; T47-S51 WeakPolarHBondContact O-CB 3.45Å; T47-S51 PolarHBondContact O-N 3.45Å; T47-S51 VanDerWaalsContact O-N 3.08Å; T47-S51 PolarHBondContact O-OG 3.48Å; T47-I82 HydrophobicContact CG2-CD1 4.1Å; T47-I85 VanDerWaalsContact OG1-CG2 3.27Å; T47-I85 WeakPolarHBondContact OG1-CG2 3.26Å; T47-L86 HydrophobicContact CG2-CD2 4.22Å; T47-M389 HydrophobicContact CG2-CE 4.02Å
48	F	94.1	Very high	92.6	Very high	4 Å²	4	18.9 Å²	18.9	2%	0.018	9%	0.092	C	C	.	.	H	α-helix	trans	-61.4	-46.4	176.4	-178.9	-95.7	0	0	0	112	F17 F20 F44 V46 S51 C52 I358 L362 M389 F393	F17-F48 WeakPolarHBondContact O-CD1 3.48Å; F20-F48 AromaticContact CD1-CE1 3.49Å; F20-F48 HydrophobicContact CD1-CE1 3.49Å; F20-F48 VanDerWaalsContact CD1-CE1 3.49Å; F20-F48 AromaticContact CD1-CZ 3.59Å; F20-F48 HydrophobicContact CD1-CZ 3.59Å; F20-F48 HydrophobicContact CE1-CE1 4.21Å; F20-F48 AromaticContact CE1-CZ 3.83Å; F20-F48 HydrophobicContact CE1-CZ 3.83Å; F20-F48 HydrophobicContact CG-CE1 4.45Å; F44-F48 WeakPolarHBondContact O-CB 3.46Å; F44-F48 PolarHBondContact O-N 3.42Å; V46-F48 VanDerWaalsContact C-N 3.29Å; V46-F48 PolarHBondContact O-N 2.9Å; F48-S51 WeakPolarHBondContact O-CB 3.5Å; F48-S51 PolarHBondContact O-N 3.26Å; F48-C52 WeakPolarHBondContact CE1-SG 3.34Å; F48-C52 WeakPolarHBondContact CZ-SG 3.46Å; F48-C52 PolarHBondContact O-N 3.25Å; F48-C52 PolarHBondContact O-SG 2.88Å; F48-I358 HydrophobicContact CE2-CG2 4.4Å; F48-L362 HydrophobicContact CD2-CD2 4.37Å; F48-L362 HydrophobicContact CE2-CD1 4.1Å; F48-L362 HydrophobicContact CE2-CD2 4.02Å; F48-L362 HydrophobicContact CE2-CG 4.49Å; F48-M389 HydrophobicContact CB-CE 3.72Å; F48-M389 HydrophobicContact CB-SD 4.37Å; F48-M389 HydrophobicContact CD2-CE 4.23Å; F48-M389 HydrophobicContact CD2-SD 3.77Å; F48-M389 HydrophobicContact CG-CE 4.5Å; F48-F393 HydrophobicContact CD2-CE2 4.49Å
49	A	95.9	Very high	92.6	Very high	0 Å²	0	13.6 Å²	13.6	0%	0	7%	0.074	C	C	.	.	H	α-helix	trans	-61.4	-54.6	-179.1	0	0	0	0	0	112	F17 F18 S45 V46 S51 C52 T53	F17-A49 HydrophobicContact CB-CB 4.02Å; F18-A49 HydrophobicContact CB-CB 4.02Å; S45-A49 WeakPolarHBondContact O-CB 3.41Å; S45-A49 PolarHBondContact O-N 2.82Å; V46-A49 PolarHBondContact O-N 3.43Å; A49-S51 PolarHBondContact O-N 2.91Å; A49-C52 PolarHBondContact O-N 3.34Å; A49-T53 PolarHBondContact O-N 2.65Å; A49-T53 PolarHBondContact O-OG1 3.1Å
50	F	95.9	Very high	92.5	Very high	34 Å²	34	12.1 Å²	12.1	15%	0.149	6%	0.063	C	C	.	.	H	α-helix	trans	-61.4	-27.8	178.2	-82.7	-84.4	0	0	0	112.9	Q14 V46 M54 N78 V81 I82 I85	Q14-F50 VanDerWaalsContact NE2-CD2 3.27Å; V46-F50 HydrophobicContact CG1-CD2 3.54Å; V46-F50 HydrophobicContact CG1-CE2 3.67Å; V46-F50 WeakPolarHBondContact O-CD2 3.42Å; V46-F50 PolarHBondContact O-N 3.3Å; F50-M54 VanDerWaalsContact O-CG 3.25Å; F50-M54 WeakPolarHBondContact O-CG 3.43Å; F50-M54 PolarHBondContact O-N 2.94Å; F50-N78 WeakPolarHBondContact CD1-OD1 3.43Å; F50-N78 PolarHBondContact O-ND2 3.05Å; F50-N78 PolarHBondContact O-OD1 3.09Å; F50-V81 HydrophobicContact CD1-CB 3.94Å; F50-V81 HydrophobicContact CD1-CG1 3.79Å; F50-V81 HydrophobicContact CD2-CG1 3.98Å; F50-V81 HydrophobicContact CE1-CB 3.67Å; F50-V81 HydrophobicContact CE1-CG1 3.51Å; F50-V81 HydrophobicContact CE1-CG2 4.1Å; F50-V81 HydrophobicContact CE2-CG1 3.67Å; F50-V81 HydrophobicContact CG-CG1 4.07Å; F50-V81 HydrophobicContact CZ-CB 4.09Å; F50-V81 HydrophobicContact CZ-CG1 3.45Å; F50-V81 VanDerWaalsContact CZ-CG1 3.45Å; F50-V81 HydrophobicContact CZ-CG2 4.37Å; F50-I82 HydrophobicContact CB-CB 4.37Å; F50-I82 HydrophobicContact CB-CD1 3.9Å; F50-I85 HydrophobicContact CD2-CD1 4.24Å
51	S	93.9	Very high	92.2	Very high	0 Å²	0	12.7 Å²	12.7	0%	0	7%	0.066	C	C	.	.	H	α-helix	trans	-72.3	-42.8	173.3	-58.6	0	0	0	0	112.6	T47 F48 A49 T53 M54 F55	T47-S51 VanDerWaalsContact O-CB 3.32Å; T47-S51 WeakPolarHBondContact O-CB 3.45Å; T47-S51 PolarHBondContact O-N 3.45Å; T47-S51 VanDerWaalsContact O-N 3.08Å; T47-S51 PolarHBondContact O-OG 3.48Å; F48-S51 WeakPolarHBondContact O-CB 3.5Å; F48-S51 PolarHBondContact O-N 3.26Å; A49-S51 PolarHBondContact O-N 2.91Å; S51-T53 VanDerWaalsContact C-N 3.32Å; S51-M54 WeakPolarHBondContact O-CB 3.45Å; S51-M54 PolarHBondContact O-N 3.07Å; S51-F55 WeakPolarHBondContact O-CD2 3.37Å
52	C	93.1	Very high	91.8	Very high	7 Å²	7	12.7 Å²	12.7	5%	0.047	7%	0.066	C	C	.	.	H	α-helix	trans	-64.9	-38.5	175.4	-66.3	0	0	0	0	111.6	F17 F48 A49 M54 F55 E56	F17-C52 HydrophobicContact CB-CB 4.09Å; F17-C52 HydrophobicContact CD1-CB 3.84Å; F17-C52 HydrophobicContact CD2-CB 3.62Å; F17-C52 HydrophobicContact CE1-CB 4.13Å; F17-C52 HydrophobicContact CE2-CB 3.9Å; F17-C52 HydrophobicContact CG-CB 3.59Å; F17-C52 HydrophobicContact CZ-CB 4.16Å; F48-C52 WeakPolarHBondContact CE1-SG 3.34Å; F48-C52 WeakPolarHBondContact CZ-SG 3.46Å; F48-C52 PolarHBondContact O-N 3.25Å; F48-C52 PolarHBondContact O-SG 2.88Å; A49-C52 PolarHBondContact O-N 3.34Å; C52-M54 PolarHBondContact O-N 3.23Å; C52-F55 WeakPolarHBondContact O-CB 3.37Å; C52-F55 PolarHBondContact O-N 2.94Å; C52-E56 PolarHBondContact O-N 3.13Å
53	T	94.3	Very high	91.3	Very high	3 Å²	3	15 Å²	15	2%	0.018	8%	0.076	C	C	.	.	H	α-helix	trans	-61.1	-30.9	176	-55.1	0	0	0	0	112.4	M10 Q14 A49 S51 F55 E56 L57 N78	M10-T53 HydrophobicContact CE-CG2 3.46Å; M10-T53 VanDerWaalsContact CE-CG2 3.46Å; Q14-T53 PolarHBondContact OE1-OG1 3.35Å; A49-T53 PolarHBondContact O-N 2.65Å; A49-T53 PolarHBondContact O-OG1 3.1Å; S51-T53 VanDerWaalsContact C-N 3.32Å; T53-F55 VanDerWaalsContact C-N 3.31Å; T53-F55 PolarHBondContact O-N 3.38Å; T53-E56 PolarHBondContact O-N 3.46Å; T53-L57 HydrophobicContact CG2-CD1 4.3Å; T53-L57 HydrophobicContact CG2-CG 4.38Å; T53-L57 WeakPolarHBondContact O-CB 3.32Å; T53-L57 VanDerWaalsContact O-CG 3.24Å; T53-L57 WeakPolarHBondContact O-CG 3.41Å; T53-L57 PolarHBondContact O-N 2.83Å; T53-N78 WeakPolarHBondContact CB-OD1 3.47Å; T53-N78 WeakPolarHBondContact CG2-OD1 3.46Å
54	M	91.3	Very high	90.8	Very high	1 Å²	1	16.3 Å²	16.3	1%	0.005	10%	0.095	C	C	.	.	H	α-helix	trans	-59.8	-44.2	171.9	-57.8	-109.4	-90.3	0	0	111.8	F50 S51 C52 L57 I58 W75 N78 L79 I82 V394 V397	F50-M54 VanDerWaalsContact O-CG 3.25Å; F50-M54 WeakPolarHBondContact O-CG 3.43Å; F50-M54 PolarHBondContact O-N 2.94Å; S51-M54 WeakPolarHBondContact O-CB 3.45Å; S51-M54 PolarHBondContact O-N 3.07Å; C52-M54 PolarHBondContact O-N 3.23Å; M54-L57 PolarHBondContact O-N 3.1Å; M54-I58 WeakPolarHBondContact O-CG1 3.29Å; M54-I58 PolarHBondContact O-N 3.13Å; M54-W75 HydrophobicContact SD-CZ3 4.27Å; M54-N78 WeakPolarHBondContact CG-ND2 3.44Å; M54-N78 PolarHBondContact SD-ND2 3.23Å; M54-N78 VanDerWaalsContact SD-ND2 3.42Å; M54-L79 HydrophobicContact CE-CD2 3.92Å; M54-L79 HydrophobicContact SD-CD2 3.45Å; M54-L79 WeakPolarHBondContact SD-CD2 3.46Å; M54-L79 HydrophobicContact SD-CG 4.2Å; M54-I82 HydrophobicContact SD-CG2 4.42Å; M54-V394 HydrophobicContact CE-CB 3.96Å; M54-V394 HydrophobicContact CE-CG1 4.32Å; M54-V394 HydrophobicContact CE-CG2 3.53Å; M54-V397 HydrophobicContact CB-CG2 3.87Å; M54-V397 HydrophobicContact CE-CB 4.31Å; M54-V397 HydrophobicContact CE-CG2 4.08Å
55	F	90.6	Very high	90.3	Very high	3 Å²	3	19 Å²	19	1%	0.013	11%	0.112	C	C	.	.	H	α-helix	trans	-72.4	-37.4	179.9	-66.4	-56.9	0	0	0	112.1	S51 C52 T53 L57 I58 I59 I354 I358 F393 V397 I400	S51-F55 WeakPolarHBondContact O-CD2 3.37Å; C52-F55 WeakPolarHBondContact O-CB 3.37Å; C52-F55 PolarHBondContact O-N 2.94Å; T53-F55 VanDerWaalsContact C-N 3.31Å; T53-F55 PolarHBondContact O-N 3.38Å; F55-L57 VanDerWaalsContact C-N 3.32Å; F55-L57 PolarHBondContact O-N 3.34Å; F55-I58 HydrophobicContact CD1-CD1 4.33Å; F55-I58 WeakPolarHBondContact O-CB 3.37Å; F55-I58 PolarHBondContact O-N 3.23Å; F55-I59 PolarHBondContact O-N 2.88Å; F55-I354 HydrophobicContact CB-CD1 3.99Å; F55-I354 HydrophobicContact CB-CG1 4.17Å; F55-I354 HydrophobicContact CB-CG2 3.64Å; F55-I354 HydrophobicContact CD1-CB 4.42Å; F55-I354 HydrophobicContact CD1-CD1 4.07Å; F55-I354 HydrophobicContact CD1-CG1 3.61Å; F55-I354 HydrophobicContact CD1-CG2 4.12Å; F55-I354 HydrophobicContact CD2-CG2 4.09Å; F55-I354 HydrophobicContact CE1-CG1 4.21Å; F55-I354 HydrophobicContact CG-CB 4.49Å; F55-I354 HydrophobicContact CG-CD1 4.38Å; F55-I354 HydrophobicContact CG-CG1 4.06Å; F55-I354 HydrophobicContact CG-CG2 3.71Å; F55-I358 HydrophobicContact CD2-CD1 3.94Å; F55-I358 HydrophobicContact CD2-CG1 4.24Å; F55-I358 HydrophobicContact CE2-CD1 4.24Å; F55-I358 HydrophobicContact CE2-CG1 4.02Å; F55-F393 HydrophobicContact CE2-CB 4.15Å; F55-F393 AromaticContact CE2-CD1 3.37Å; F55-F393 HydrophobicContact CE2-CD1 3.37Å; F55-F393 AromaticContact CE2-CE1 3.83Å; F55-F393 HydrophobicContact CE2-CE1 3.83Å; F55-F393 AromaticContact CE2-CG 3.89Å; F55-F393 HydrophobicContact CE2-CG 3.89Å; F55-F393 HydrophobicContact CZ-CB 4.3Å; F55-F393 AromaticContact CZ-CD1 3.65Å; F55-F393 HydrophobicContact CZ-CD1 3.65Å; F55-F393 HydrophobicContact CZ-CE1 4.34Å; F55-F393 HydrophobicContact CZ-CG 4.31Å; F55-V397 HydrophobicContact CD1-CG2 3.98Å; F55-V397 HydrophobicContact CE1-CG2 3.77Å; F55-V397 HydrophobicContact CZ-CG2 4.44Å; F55-I400 HydrophobicContact CD1-CD1 4.39Å; F55-I400 HydrophobicContact CE1-CD1 3.9Å
56	E	91.8	Very high	89.9	Confident	28 Å²	28	20.1 Å²	20.1	13%	0.131	12%	0.117	C	C	.	.	H	α-helix	trans	-59.7	-43.5	171.8	-177.5	179.9	-145.3	0	0	111.4	S13 F17 C52 T53 I58 I59 F60	S13-E56 VanDerWaalsContact CB-CD 3.44Å; S13-E56 WeakPolarHBondContact CB-OE1 3.47Å; S13-E56 WeakPolarHBondContact CB-OE2 3.36Å; S13-E56 VanDerWaalsContact OG-CD 3.25Å; S13-E56 PolarHBondContact OG-OE1 3Å; S13-E56 PolarHBondContact OG-OE2 2.64Å; F17-E56 HydrophobicContact CE2-CB 4.06Å; F17-E56 WeakPolarHBondContact CE2-OE2 3.45Å; F17-E56 HydrophobicContact CZ-CB 4.25Å; C52-E56 PolarHBondContact O-N 3.13Å; T53-E56 PolarHBondContact O-N 3.46Å; E56-I58 VanDerWaalsContact C-N 3.28Å; E56-I58 PolarHBondContact O-N 2.98Å; E56-I59 CarbonylContact O-C 3.44Å; E56-I59 WeakPolarHBondContact O-CA 3.45Å; E56-I59 WeakPolarHBondContact O-CB 3.47Å; E56-I59 PolarHBondContact O-N 3.37Å; E56-F60 HydrophobicContact CG-CD1 4.5Å; E56-F60 HydrophobicContact CG-CD2 4.08Å; E56-F60 HydrophobicContact CG-CE1 4.04Å; E56-F60 HydrophobicContact CG-CE2 3.59Å; E56-F60 HydrophobicContact CG-CZ 3.56Å; E56-F60 WeakPolarHBondContact O-CG 3.38Å; E56-F60 PolarHBondContact O-N 2.84Å; E56-F60 VanDerWaalsContact OE1-CZ 3.22Å; E56-F60 WeakPolarHBondContact OE1-CZ 3.29Å
57	L	90.9	Very high	89.6	Confident	0 Å²	0	22.2 Å²	22.2	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-63.7	-31.4	176.8	-74.6	172	0	0	0	112.9	M10 T53 M54 F55 E61 H74 W75 N78	M10-L57 HydrophobicContact CE-CD1 4.46Å; M10-L57 HydrophobicContact CE-CD2 3.57Å; M10-L57 HydrophobicContact CE-CG 3.88Å; M10-L57 HydrophobicContact SD-CD2 3.87Å; T53-L57 HydrophobicContact CG2-CD1 4.3Å; T53-L57 HydrophobicContact CG2-CG 4.38Å; T53-L57 WeakPolarHBondContact O-CB 3.32Å; T53-L57 VanDerWaalsContact O-CG 3.24Å; T53-L57 WeakPolarHBondContact O-CG 3.41Å; T53-L57 PolarHBondContact O-N 2.83Å; M54-L57 PolarHBondContact O-N 3.1Å; F55-L57 VanDerWaalsContact C-N 3.32Å; F55-L57 PolarHBondContact O-N 3.34Å; L57-E61 WeakPolarHBondContact O-CB 3.24Å; L57-E61 PolarHBondContact O-N 3.34Å; L57-H74 HydrophobicContact CD2-CB 4.03Å; L57-W75 HydrophobicContact CB-CD2 4.1Å; L57-W75 HydrophobicContact CB-CH2 4.35Å; L57-W75 HydrophobicContact CB-CZ2 3.66Å; L57-W75 HydrophobicContact CD1-CD2 4.02Å; L57-W75 HydrophobicContact CD1-CE3 4.38Å; L57-W75 HydrophobicContact CD1-CG 4.1Å; L57-N78 HydrophobicContact CD1-CB 4.13Å
58	I	87.6	Confident	89.2	Confident	0 Å²	0	25.2 Å²	25.2	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-65.1	-44.8	170	-66.6	172.6	0	0	0	110.4	M54 F55 E56 F60 E61 I62 W75 V350 V397 I400 M404 I412	M54-I58 WeakPolarHBondContact O-CG1 3.29Å; M54-I58 PolarHBondContact O-N 3.13Å; F55-I58 HydrophobicContact CD1-CD1 4.33Å; F55-I58 WeakPolarHBondContact O-CB 3.37Å; F55-I58 PolarHBondContact O-N 3.23Å; E56-I58 VanDerWaalsContact C-N 3.28Å; E56-I58 PolarHBondContact O-N 2.98Å; I58-F60 VanDerWaalsContact C-N 3.33Å; I58-F60 PolarHBondContact O-N 3.29Å; I58-E61 WeakPolarHBondContact O-CB 3.48Å; I58-E61 PolarHBondContact O-N 3.43Å; I58-I62 HydrophobicContact CG2-CD1 3.89Å; I58-I62 HydrophobicContact CG2-CG1 4.5Å; I58-I62 WeakPolarHBondContact O-CG1 3.45Å; I58-I62 PolarHBondContact O-N 2.95Å; I58-W75 HydrophobicContact CD1-CH2 4.42Å; I58-W75 HydrophobicContact CG1-CH2 3.74Å; I58-W75 HydrophobicContact CG1-CZ2 3.68Å; I58-V350 HydrophobicContact CG2-CG1 3.93Å; I58-V397 HydrophobicContact CD1-CB 4.37Å; I58-V397 HydrophobicContact CD1-CG1 4.05Å; I58-V397 HydrophobicContact CD1-CG2 3.94Å; I58-I400 HydrophobicContact CD1-CG2 4.31Å; I58-M404 HydrophobicContact CG2-CE 4.08Å; I58-M404 HydrophobicContact CG2-SD 3.68Å; I58-I412 HydrophobicContact CG1-CD1 4.19Å
59	I	86.8	Confident	89	Confident	46 Å²	46	29.3 Å²	29.3	24%	0.236	18%	0.177	C	C	.	.	H	α-helix	trans	-61.3	-43.7	178.1	-73.6	164.9	0	0	0	110.6	F55 E56 E61 I62 L63 F347 I354	F55-I59 PolarHBondContact O-N 2.88Å; E56-I59 CarbonylContact O-C 3.44Å; E56-I59 WeakPolarHBondContact O-CA 3.45Å; E56-I59 WeakPolarHBondContact O-CB 3.47Å; E56-I59 PolarHBondContact O-N 3.37Å; I59-E61 VanDerWaalsContact C-N 3.31Å; I59-E61 PolarHBondContact O-N 3.04Å; I59-I62 PolarHBondContact O-N 3.37Å; I59-L63 HydrophobicContact CG2-CD1 3.77Å; I59-L63 HydrophobicContact CG2-CG 4.41Å; I59-L63 WeakPolarHBondContact O-CB 3.47Å; I59-L63 WeakPolarHBondContact O-CG 3.25Å; I59-L63 PolarHBondContact O-N 2.92Å; I59-F347 HydrophobicContact CG2-CE2 4Å; I59-I354 HydrophobicContact CD1-CD1 4.19Å; I59-I354 HydrophobicContact CG1-CD1 4.2Å
60	F	88.8	Confident	88.7	Confident	25 Å²	25	29.4 Å²	29.4	11%	0.11	18%	0.178	C	C	.	.	H	α-helix	trans	-66.1	-32.4	176.4	-68.1	-14.1	0	0	0	113	I9 M10 E56 I58 G64 V65 L66	I9-F60 HydrophobicContact CG2-CZ 4.44Å; M10-F60 HydrophobicContact SD-CD2 3.8Å; M10-F60 HydrophobicContact SD-CE2 3.55Å; M10-F60 VanDerWaalsContact SD-CE2 3.55Å; E56-F60 HydrophobicContact CG-CD1 4.5Å; E56-F60 HydrophobicContact CG-CD2 4.08Å; E56-F60 HydrophobicContact CG-CE1 4.04Å; E56-F60 HydrophobicContact CG-CE2 3.59Å; E56-F60 HydrophobicContact CG-CZ 3.56Å; E56-F60 WeakPolarHBondContact O-CG 3.38Å; E56-F60 PolarHBondContact O-N 2.84Å; E56-F60 VanDerWaalsContact OE1-CZ 3.22Å; E56-F60 WeakPolarHBondContact OE1-CZ 3.29Å; I58-F60 VanDerWaalsContact C-N 3.33Å; I58-F60 PolarHBondContact O-N 3.29Å; F60-G64 WeakPolarHBondContact O-CA 3.48Å; F60-G64 PolarHBondContact O-N 3.3Å; F60-V65 HydrophobicContact CB-CB 4.28Å; F60-V65 HydrophobicContact CD1-CB 3.93Å; F60-V65 HydrophobicContact CD1-CG1 4.08Å; F60-V65 HydrophobicContact CD1-CG2 4.49Å; F60-V65 HydrophobicContact CE1-CG1 4.3Å; F60-V65 HydrophobicContact CG-CB 4.23Å; F60-V65 HydrophobicContact CG-CG1 4.43Å; F60-V65 PolarHBondContact O-N 2.96Å; F60-L66 HydrophobicContact CD2-CD1 3.6Å; F60-L66 HydrophobicContact CD2-CG 4.19Å; F60-L66 HydrophobicContact CE2-CD1 4.07Å; F60-L66 HydrophobicContact CG-CD1 4.43Å
61	E	85.8	Confident	88.5	Confident	12 Å²	12	28.7 Å²	28.7	6%	0.056	18%	0.175	C	C	.	.	H	α-helix	trans	-65.5	-46	173	-170.1	66.6	-172.2	0	0	111.7	L57 I58 I59 G64 R71 Y408 I411	L57-E61 WeakPolarHBondContact O-CB 3.24Å; L57-E61 PolarHBondContact O-N 3.34Å; I58-E61 WeakPolarHBondContact O-CB 3.48Å; I58-E61 PolarHBondContact O-N 3.43Å; I59-E61 VanDerWaalsContact C-N 3.31Å; I59-E61 PolarHBondContact O-N 3.04Å; E61-G64 PolarHBondContact O-N 2.9Å; E61-R71 WeakPolarHBondContact OE2-CD 3.24Å; E61-R71 IonicContact OE2-CZ 3.01Å; E61-R71 IonicContact OE2-NE 3.99Å; E61-R71 PolarHBondContact OE2-NE 3.29Å; E61-R71 IonicContact OE2-NH2 2.76Å; E61-Y408 VanDerWaalsContact CG-O 3.26Å; E61-Y408 WeakPolarHBondContact CG-O 3.26Å; E61-I411 WeakPolarHBondContact OE2-CD1 2.92Å
62	I	81.6	Confident	88.3	Confident	5 Å²	5	32.1 Å²	32.1	3%	0.026	19%	0.188	C	C	.	.	H	α-helix	trans	-68.2	-39.4	-179.9	-62.6	166.1	0	0	0	111.8	I58 I59 G64 Q343 F347 V350 M404	I58-I62 HydrophobicContact CG2-CD1 3.89Å; I58-I62 HydrophobicContact CG2-CG1 4.5Å; I58-I62 WeakPolarHBondContact O-CG1 3.45Å; I58-I62 PolarHBondContact O-N 2.95Å; I59-I62 PolarHBondContact O-N 3.37Å; I62-G64 VanDerWaalsContact C-N 3.33Å; I62-Q343 PolarHBondContact O-NE2 3.04Å; I62-F347 HydrophobicContact CB-CD2 4.34Å; I62-F347 HydrophobicContact CG2-CB 3.89Å; I62-F347 HydrophobicContact CG2-CD2 3.85Å; I62-F347 HydrophobicContact CG2-CG 4.32Å; I62-V350 HydrophobicContact CD1-CB 4.15Å; I62-V350 HydrophobicContact CD1-CG1 3.96Å; I62-V350 HydrophobicContact CD1-CG2 4.26Å; I62-M404 HydrophobicContact CD1-SD 3.87Å; I62-M404 HydrophobicContact CG1-SD 4.12Å
63	L	82.6	Confident	88.3	Confident	88 Å²	88	36.5 Å²	36.5	46%	0.461	21%	0.207	S	C	.	.	H	α-helix	trans	-82.1	-10.2	-179.5	-66.2	178.2	0	0	0	113.4	I59 V65 F347	I59-L63 HydrophobicContact CG2-CD1 3.77Å; I59-L63 HydrophobicContact CG2-CG 4.41Å; I59-L63 WeakPolarHBondContact O-CB 3.47Å; I59-L63 WeakPolarHBondContact O-CG 3.25Å; I59-L63 PolarHBondContact O-N 2.92Å; L63-V65 HydrophobicContact CB-CG2 3.69Å; L63-V65 HydrophobicContact CD1-CG2 4.45Å; L63-V65 PolarHBondContact O-N 3.41Å; L63-F347 HydrophobicContact CD1-CE2 3.79Å; L63-F347 HydrophobicContact CD1-CZ 3.97Å; L63-F347 HydrophobicContact CD2-CD2 3.89Å; L63-F347 HydrophobicContact CD2-CE1 4.39Å; L63-F347 HydrophobicContact CD2-CE2 3.67Å; L63-F347 HydrophobicContact CD2-CG 4.34Å; L63-F347 HydrophobicContact CD2-CZ 3.94Å; L63-F347 HydrophobicContact CG-CD2 4.1Å; L63-F347 HydrophobicContact CG-CE2 3.64Å; L63-F347 HydrophobicContact CG-CZ 4.18Å
64	G	82.4	Confident	88.3	Confident	49 Å²	49	36.9 Å²	36.9	51%	0.505	21%	0.208	S	C	.	.	T	Hydrogen-bonded Turn	trans	65.2	24.8	-174.4	0	0	0	0	0	113.7	F60 E61 I62	F60-G64 WeakPolarHBondContact O-CA 3.48Å; F60-G64 PolarHBondContact O-N 3.3Å; E61-G64 PolarHBondContact O-N 2.9Å; I62-G64 VanDerWaalsContact C-N 3.33Å
65	V	82.9	Confident	88.3	Confident	57 Å²	57	36.9 Å²	36.9	35%	0.345	21%	0.208	S	C	.	.			trans	-77.9	144.7	177.3	-179.1	0	0	0	0	108.7	F60 L63 R71	F60-V65 HydrophobicContact CB-CB 4.28Å; F60-V65 HydrophobicContact CD1-CB 3.93Å; F60-V65 HydrophobicContact CD1-CG1 4.08Å; F60-V65 HydrophobicContact CD1-CG2 4.49Å; F60-V65 HydrophobicContact CE1-CG1 4.3Å; F60-V65 HydrophobicContact CG-CB 4.23Å; F60-V65 HydrophobicContact CG-CG1 4.43Å; F60-V65 PolarHBondContact O-N 2.96Å; L63-V65 HydrophobicContact CB-CG2 3.69Å; L63-V65 HydrophobicContact CD1-CG2 4.45Å; L63-V65 PolarHBondContact O-N 3.41Å; V65-R71 WeakPolarHBondContact O-CD 3.37Å; V65-R71 PolarHBondContact O-NH1 3.29Å
66	L	86.6	Confident	88.3	Confident	23 Å²	23	41.9 Å²	41.9	12%	0.12	23%	0.23	C	C	.	.	S	Bend	trans	70.9	164.3	-171.7	-44.3	176.4	0	0	0	114.1	D6 I9 M10 F60 R71	D6-L66 HydrophobicContact CB-CB 4.4Å; D6-L66 HydrophobicContact CB-CD2 3.78Å; I9-L66 HydrophobicContact CB-CD2 4.45Å; I9-L66 HydrophobicContact CD1-CD2 4Å; I9-L66 HydrophobicContact CG2-CD2 4.48Å; M10-L66 HydrophobicContact CG-CD1 4.01Å; M10-L66 HydrophobicContact SD-CD1 3.72Å; F60-L66 HydrophobicContact CD2-CD1 3.6Å; F60-L66 HydrophobicContact CD2-CG 4.19Å; F60-L66 HydrophobicContact CE2-CD1 4.07Å; F60-L66 HydrophobicContact CG-CD1 4.43Å; L66-R71 HydrophobicContact CB-CG 3.88Å; L66-R71 HydrophobicContact CD1-CG 4.35Å; L66-R71 PolarHBondContact O-NH1 2.71Å
67	N	89.1	Confident	88.4	Confident	81 Å²	81	44.1 Å²	44.1	43%	0.433	24%	0.241	S	C	.	.			trans	-75.7	143	173.7	-167	-7.8	0	0	0	111	D6 S69 S70 R71	D6-N67 WeakPolarHBondContact OD2-CB 3.32Å; D6-N67 PolarHBondContact OD2-N 3.37Å; N67-S69 VanDerWaalsContact C-N 3.31Å; N67-S69 PolarHBondContact O-N 3.43Å; N67-S70 WeakPolarHBondContact O-CA 3.41Å; N67-S70 VanDerWaalsContact O-CB 3.3Å; N67-S70 WeakPolarHBondContact O-CB 3.46Å; N67-S70 PolarHBondContact O-N 2.94Å; N67-R71 PolarHBondContact O-N 2.61Å
68	S	86.9	Confident	88.6	Confident	63 Å²	63	44.3 Å²	44.3	44%	0.441	24%	0.242	S	C	.	.	H	α-helix	trans	-56.1	-41.5	-177.1	-56.6	0	0	0	0	113.1	S70 R71 Y72	S68-S70 VanDerWaalsContact C-N 3.3Å; S68-S70 PolarHBondContact O-N 3.33Å; S68-R71 PolarHBondContact O-N 3.3Å; S68-R71 PolarHBondContact OG-NH2 2.84Å; S68-R71 VanDerWaalsContact OG-NH2 3.16Å; S68-Y72 WeakPolarHBondContact O-CB 3.4Å; S68-Y72 PolarHBondContact O-N 2.59Å
69	S	89.3	Confident	88.8	Confident	90 Å²	90	44.3 Å²	44.3	63%	0.629	24%	0.242	S	C	*	.	H	α-helix	trans	-66.3	-33.2	176.4	-52.3	0	0	0	0	112.5	N67 F73	N67-S69 VanDerWaalsContact C-N 3.31Å; N67-S69 PolarHBondContact O-N 3.43Å; S69-F73 PolarHBondContact O-N 2.91Å; S69-F73 VanDerWaalsContact O-N 3.16Å
70	S	91.6	Very high	89.1	Confident	3 Å²	3	44.6 Å²	44.6	2%	0.021	25%	0.248	C	C	.	.	H	α-helix	trans	-70.4	-46.7	176.2	-166.8	0	0	0	0	110.7	D6 N67 S68 Y72 F73 H74	D6-S70 VanDerWaalsContact CB-OG 3.23Å; D6-S70 WeakPolarHBondContact CB-OG 3.24Å; D6-S70 VanDerWaalsContact OD2-CB 3.26Å; D6-S70 WeakPolarHBondContact OD2-CB 3.24Å; D6-S70 PolarHBondContact OD2-OG 2.92Å; N67-S70 WeakPolarHBondContact O-CA 3.41Å; N67-S70 VanDerWaalsContact O-CB 3.3Å; N67-S70 WeakPolarHBondContact O-CB 3.46Å; N67-S70 PolarHBondContact O-N 2.94Å; S68-S70 VanDerWaalsContact C-N 3.3Å; S68-S70 PolarHBondContact O-N 3.33Å; S70-Y72 VanDerWaalsContact C-N 3.33Å; S70-Y72 PolarHBondContact O-N 3.06Å; S70-F73 PolarHBondContact O-N 2.99Å; S70-H74 PolarHBondContact O-CD2 2.82Å; S70-H74 PolarHBondContact O-N 3.3Å; S70-H74 PolarHBondContact OG-CD2 3.38Å
71	R	90.6	Very high	89.4	Confident	18 Å²	18	45.4 Å²	45.4	7%	0.068	25%	0.254	C	S	.	.	H	α-helix	trans	-55.6	-47.9	174.5	-70.1	-160	-64.8	-87.3	-5.1	111.6	E61 V65 L66 N67 S68 F73 H74 W75 I411	E61-R71 WeakPolarHBondContact OE2-CD 3.24Å; E61-R71 IonicContact OE2-CZ 3.01Å; E61-R71 IonicContact OE2-NE 3.99Å; E61-R71 PolarHBondContact OE2-NE 3.29Å; E61-R71 IonicContact OE2-NH2 2.76Å; V65-R71 WeakPolarHBondContact O-CD 3.37Å; V65-R71 PolarHBondContact O-NH1 3.29Å; L66-R71 HydrophobicContact CB-CG 3.88Å; L66-R71 HydrophobicContact CD1-CG 4.35Å; L66-R71 PolarHBondContact O-NH1 2.71Å; N67-R71 PolarHBondContact O-N 2.61Å; S68-R71 PolarHBondContact O-N 3.3Å; S68-R71 PolarHBondContact OG-NH2 2.84Å; S68-R71 VanDerWaalsContact OG-NH2 3.16Å; R71-F73 VanDerWaalsContact C-N 3.34Å; R71-F73 PolarHBondContact O-N 3.17Å; R71-H74 PolarHBondContact O-N 2.9Å; R71-W75 WeakPolarHBondContact O-CB 3.33Å; R71-W75 VanDerWaalsContact O-CD1 3.32Å; R71-W75 PolarHBondContact O-N 3.18Å; R71-I411 HydrophobicContact CB-CD1 4.22Å
72	Y	90.6	Very high	89.9	Confident	73 Å²	73	44.8 Å²	44.8	29%	0.286	25%	0.252	S	S	.	.	H	α-helix	trans	-57.5	-46.1	177.8	179	-92.4	0	0	0	112.3	S68 S70 W75 K76 I411 E414 V415	S68-Y72 WeakPolarHBondContact O-CB 3.4Å; S68-Y72 PolarHBondContact O-N 2.59Å; S70-Y72 VanDerWaalsContact C-N 3.33Å; S70-Y72 PolarHBondContact O-N 3.06Å; Y72-W75 PolarHBondContact O-N 3.37Å; Y72-K76 HydrophobicContact CE1-CD 4.47Å; Y72-K76 PolarHBondContact O-N 2.9Å; Y72-I411 HydrophobicContact CD2-CG2 4.34Å; Y72-E414 HydrophobicContact CE2-CB 4.46Å; Y72-E414 HydrophobicContact CE2-CG 3.98Å; Y72-E414 WeakPolarHBondContact CE2-OE1 3.13Å; Y72-V415 HydrophobicContact CD2-CG2 3.69Å; Y72-V415 HydrophobicContact CE2-CG2 3.65Å
73	F	92.6	Very high	90.4	Very high	99 Å²	99	44.7 Å²	44.7	43%	0.434	25%	0.251	S	S	.	.	H	α-helix	trans	-61	-48.9	176.8	175.1	-97.1	0	0	0	112.1	F3 S69 S70 R71 W75 K76 M77	F3-F73 HydrophobicContact CE2-CB 4.26Å; F3-F73 AromaticContact CE2-CD1 3.75Å; F3-F73 HydrophobicContact CE2-CD1 3.75Å; F3-F73 HydrophobicContact CE2-CE1 4.39Å; F3-F73 HydrophobicContact CE2-CG 4.1Å; F3-F73 AromaticContact CZ-CD1 3.58Å; F3-F73 HydrophobicContact CZ-CD1 3.58Å; F3-F73 AromaticContact CZ-CE1 3.74Å; F3-F73 HydrophobicContact CZ-CE1 3.74Å; F3-F73 HydrophobicContact CZ-CG 4.16Å; F3-F73 HydrophobicContact CZ-CZ 4.44Å; S69-F73 PolarHBondContact O-N 2.91Å; S69-F73 VanDerWaalsContact O-N 3.16Å; S70-F73 PolarHBondContact O-N 2.99Å; R71-F73 VanDerWaalsContact C-N 3.34Å; R71-F73 PolarHBondContact O-N 3.17Å; F73-W75 PolarHBondContact O-N 3.2Å; F73-K76 PolarHBondContact O-N 3.3Å; F73-M77 HydrophobicContact CE1-CE 3.94Å; F73-M77 WeakPolarHBondContact O-CB 3.47Å; F73-M77 PolarHBondContact O-N 2.74Å
74	H	93.6	Very high	91	Very high	11 Å²	11	44.5 Å²	44.5	5%	0.051	25%	0.25	C	C	.	.	H	α-helix	trans	-64.8	-38.1	179.8	-75	-67.2	0	0	0	112.4	S7 L57 S70 R71 N78	S7-H74 PolarHBondContact OG-NE2 3.06Å; L57-H74 HydrophobicContact CD2-CB 4.03Å; S70-H74 PolarHBondContact O-CD2 2.82Å; S70-H74 PolarHBondContact O-N 3.3Å; S70-H74 PolarHBondContact OG-CD2 3.38Å; R71-H74 PolarHBondContact O-N 2.9Å; H74-N78 WeakPolarHBondContact O-CB 3.46Å; H74-N78 PolarHBondContact O-N 3.04Å
75	W	91.6	Very high	91.7	Very high	1 Å²	1	43 Å²	43	0%	0.004	23%	0.23	C	C	.	.	H	α-helix	trans	-57.7	-52.1	172.1	-96.7	111.4	0	0	0	112.2	M54 L57 I58 R71 Y72 F73 M77 N78 L79 V397 I411 I412 V415	M54-W75 HydrophobicContact SD-CZ3 4.27Å; L57-W75 HydrophobicContact CB-CD2 4.1Å; L57-W75 HydrophobicContact CB-CH2 4.35Å; L57-W75 HydrophobicContact CB-CZ2 3.66Å; L57-W75 HydrophobicContact CD1-CD2 4.02Å; L57-W75 HydrophobicContact CD1-CE3 4.38Å; L57-W75 HydrophobicContact CD1-CG 4.1Å; I58-W75 HydrophobicContact CD1-CH2 4.42Å; I58-W75 HydrophobicContact CG1-CH2 3.74Å; I58-W75 HydrophobicContact CG1-CZ2 3.68Å; R71-W75 WeakPolarHBondContact O-CB 3.33Å; R71-W75 VanDerWaalsContact O-CD1 3.32Å; R71-W75 PolarHBondContact O-N 3.18Å; Y72-W75 PolarHBondContact O-N 3.37Å; F73-W75 PolarHBondContact O-N 3.2Å; W75-M77 PolarHBondContact O-N 3.44Å; W75-N78 PolarHBondContact O-N 3.48Å; W75-L79 HydrophobicContact CE3-CD1 4.2Å; W75-L79 HydrophobicContact CE3-CG 4.34Å; W75-L79 WeakPolarHBondContact O-CB 3.31Å; W75-L79 WeakPolarHBondContact O-CG 3.48Å; W75-L79 PolarHBondContact O-N 3.38Å; W75-V397 HydrophobicContact CH2-CG1 3.99Å; W75-V397 HydrophobicContact CZ3-CG1 4.21Å; W75-I411 HydrophobicContact CG-CG2 4.25Å; W75-I412 HydrophobicContact CH2-CG1 4.41Å; W75-I412 HydrophobicContact CZ2-CD1 4.06Å; W75-I412 HydrophobicContact CZ2-CG1 3.87Å; W75-V415 HydrophobicContact CB-CG1 4.23Å; W75-V415 HydrophobicContact CB-CG2 4.03Å
76	K	91.6	Very high	92.3	Very high	107 Å²	107	40.2 Å²	40.2	47%	0.465	21%	0.214	S	C	.	.	H	α-helix	trans	-64	-42.5	-179.4	-171.4	172.8	-175.5	170.7	0	112	Y72 F73 C80	Y72-K76 HydrophobicContact CE1-CD 4.47Å; Y72-K76 PolarHBondContact O-N 2.9Å; F73-K76 PolarHBondContact O-N 3.3Å; K76-C80 VanDerWaalsContact O-CB 3.31Å; K76-C80 WeakPolarHBondContact O-CB 3.47Å; K76-C80 PolarHBondContact O-N 3.38Å
77	M	93.6	Very high	92.6	Very high	76 Å²	76	39.1 Å²	39.1	37%	0.374	21%	0.208	S	C	.	.	H	α-helix	trans	-64.8	-48.3	177.5	-177.2	-114.6	-70.7	0	0	111.4	F73 W75 L79 C80 V81	F73-M77 HydrophobicContact CE1-CE 3.94Å; F73-M77 WeakPolarHBondContact O-CB 3.47Å; F73-M77 PolarHBondContact O-N 2.74Å; W75-M77 PolarHBondContact O-N 3.44Å; M77-L79 PolarHBondContact O-N 2.98Å; M77-C80 WeakPolarHBondContact O-CB 3.38Å; M77-C80 PolarHBondContact O-N 3.4Å; M77-V81 WeakPolarHBondContact O-CG2 3.47Å; M77-V81 PolarHBondContact O-N 2.86Å
78	N	94.8	Very high	92.9	Very high	4 Å²	4	38.2 Å²	38.2	2%	0.021	20%	0.2	C	C	.	.	H	α-helix	trans	-61.3	-45	179.9	-173.3	85.6	0	0	0	111.6	F50 T53 M54 L57 H74 W75 V81 I82	F50-N78 WeakPolarHBondContact CD1-OD1 3.43Å; F50-N78 PolarHBondContact O-ND2 3.05Å; F50-N78 PolarHBondContact O-OD1 3.09Å; T53-N78 WeakPolarHBondContact CB-OD1 3.47Å; T53-N78 WeakPolarHBondContact CG2-OD1 3.46Å; M54-N78 WeakPolarHBondContact CG-ND2 3.44Å; M54-N78 PolarHBondContact SD-ND2 3.23Å; M54-N78 VanDerWaalsContact SD-ND2 3.42Å; L57-N78 HydrophobicContact CD1-CB 4.13Å; H74-N78 WeakPolarHBondContact O-CB 3.46Å; H74-N78 PolarHBondContact O-N 3.04Å; W75-N78 PolarHBondContact O-N 3.48Å; N78-V81 PolarHBondContact O-N 2.85Å; N78-I82 WeakPolarHBondContact O-CG2 3.45Å; N78-I82 PolarHBondContact O-N 2.94Å
79	L	92.2	Very high	93.3	Very high	0 Å²	0	40.2 Å²	40.2	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-63.6	-41.7	175.3	-79.1	175.9	0	0	0	112.8	M54 W75 M77 V81 I82 L83 I147 V415 L416	M54-L79 HydrophobicContact CE-CD2 3.92Å; M54-L79 HydrophobicContact SD-CD2 3.45Å; M54-L79 WeakPolarHBondContact SD-CD2 3.46Å; M54-L79 HydrophobicContact SD-CG 4.2Å; W75-L79 HydrophobicContact CE3-CD1 4.2Å; W75-L79 HydrophobicContact CE3-CG 4.34Å; W75-L79 WeakPolarHBondContact O-CB 3.31Å; W75-L79 WeakPolarHBondContact O-CG 3.48Å; W75-L79 PolarHBondContact O-N 3.38Å; M77-L79 PolarHBondContact O-N 2.98Å; L79-V81 VanDerWaalsContact C-N 3.34Å; L79-V81 PolarHBondContact O-N 3.42Å; L79-I82 HydrophobicContact CD2-CG2 4.33Å; L79-I82 WeakPolarHBondContact O-CG2 3.25Å; L79-L83 VanDerWaalsContact O-CB 3.29Å; L79-L83 WeakPolarHBondContact O-CB 3.33Å; L79-L83 WeakPolarHBondContact O-CD1 3.48Å; L79-L83 WeakPolarHBondContact O-CG 3.36Å; L79-L83 PolarHBondContact O-N 3.33Å; L79-I147 HydrophobicContact CD1-CD1 4.3Å; L79-I147 HydrophobicContact CD2-CD1 3.8Å; L79-V415 HydrophobicContact CD1-CG1 3.3Å; L79-L416 HydrophobicContact CD1-CD2 4.2Å
80	C	92.9	Very high	93.6	Very high	52 Å²	52	35.9 Å²	35.9	35%	0.351	17%	0.174	S	C	.	.	H	α-helix	trans	-58.9	-48.3	175.2	-175.3	0	0	0	0	111	K76 M77 L83 L84	K76-C80 VanDerWaalsContact O-CB 3.31Å; K76-C80 WeakPolarHBondContact O-CB 3.47Å; K76-C80 PolarHBondContact O-N 3.38Å; M77-C80 WeakPolarHBondContact O-CB 3.38Å; M77-C80 PolarHBondContact O-N 3.4Å; C80-L83 PolarHBondContact O-N 2.88Å; C80-L84 WeakPolarHBondContact O-CB 3.23Å; C80-L84 VanDerWaalsContact O-CG 3.3Å; C80-L84 WeakPolarHBondContact O-CG 3.49Å; C80-L84 PolarHBondContact O-N 3.27Å
81	V	95.1	Very high	93.8	Very high	41 Å²	41	36.2 Å²	36.2	25%	0.248	18%	0.175	C	C	.	.	H	α-helix	trans	-66.1	-47	-177.9	176.1	0	0	0	0	111.8	F50 M77 N78 L79 L83 L84 I85	F50-V81 HydrophobicContact CD1-CB 3.94Å; F50-V81 HydrophobicContact CD1-CG1 3.79Å; F50-V81 HydrophobicContact CD2-CG1 3.98Å; F50-V81 HydrophobicContact CE1-CB 3.67Å; F50-V81 HydrophobicContact CE1-CG1 3.51Å; F50-V81 HydrophobicContact CE1-CG2 4.1Å; F50-V81 HydrophobicContact CE2-CG1 3.67Å; F50-V81 HydrophobicContact CG-CG1 4.07Å; F50-V81 HydrophobicContact CZ-CB 4.09Å; F50-V81 HydrophobicContact CZ-CG1 3.45Å; F50-V81 VanDerWaalsContact CZ-CG1 3.45Å; F50-V81 HydrophobicContact CZ-CG2 4.37Å; M77-V81 WeakPolarHBondContact O-CG2 3.47Å; M77-V81 PolarHBondContact O-N 2.86Å; N78-V81 PolarHBondContact O-N 2.85Å; L79-V81 VanDerWaalsContact C-N 3.34Å; L79-V81 PolarHBondContact O-N 3.42Å; V81-L83 VanDerWaalsContact C-N 3.31Å; V81-L83 PolarHBondContact O-N 3.23Å; V81-L84 PolarHBondContact O-N 2.81Å; V81-I85 HydrophobicContact CG1-CD1 3.7Å; V81-I85 HydrophobicContact CG1-CG1 4.4Å; V81-I85 WeakPolarHBondContact O-CD1 3.24Å; V81-I85 VanDerWaalsContact O-CG1 3.25Å; V81-I85 WeakPolarHBondContact O-CG1 3.4Å; V81-I85 PolarHBondContact O-N 3.42Å
82	I	95	Very high	94	Very high	0 Å²	0	38.3 Å²	38.3	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-63.7	-37.7	179.8	-166.1	65.6	0	0	0	111.5	T47 F50 M54 N78 L79 I85 L86 V394	T47-I82 HydrophobicContact CG2-CD1 4.1Å; F50-I82 HydrophobicContact CB-CB 4.37Å; F50-I82 HydrophobicContact CB-CD1 3.9Å; M54-I82 HydrophobicContact SD-CG2 4.42Å; N78-I82 WeakPolarHBondContact O-CG2 3.45Å; N78-I82 PolarHBondContact O-N 2.94Å; L79-I82 HydrophobicContact CD2-CG2 4.33Å; L79-I82 WeakPolarHBondContact O-CG2 3.25Å; I82-I85 PolarHBondContact O-N 3.5Å; I82-L86 HydrophobicContact CD1-CD1 4.4Å; I82-L86 HydrophobicContact CD1-CG 4.48Å; I82-L86 HydrophobicContact CG1-CD1 3.88Å; I82-L86 HydrophobicContact CG1-CG 4.34Å; I82-L86 WeakPolarHBondContact O-CB 3.14Å; I82-L86 VanDerWaalsContact O-CG 3.26Å; I82-L86 WeakPolarHBondContact O-CG 3.46Å; I82-L86 PolarHBondContact O-N 2.91Å; I82-V394 HydrophobicContact CG1-CG2 4.16Å; I82-V394 HydrophobicContact CG2-CG2 4.25Å
83	L	94	Very high	94.2	Very high	2 Å²	2	38.1 Å²	38.1	1%	0.01	18%	0.184	C	C	.	.	H	α-helix	trans	-69.2	-40.1	177.1	-67.8	171.7	0	0	0	112	L79 C80 V81 I85 L86 V87 I143 L146 I147 V150	L79-L83 VanDerWaalsContact O-CB 3.29Å; L79-L83 WeakPolarHBondContact O-CB 3.33Å; L79-L83 WeakPolarHBondContact O-CD1 3.48Å; L79-L83 WeakPolarHBondContact O-CG 3.36Å; L79-L83 PolarHBondContact O-N 3.33Å; C80-L83 PolarHBondContact O-N 2.88Å; V81-L83 VanDerWaalsContact C-N 3.31Å; V81-L83 PolarHBondContact O-N 3.23Å; L83-I85 VanDerWaalsContact C-N 3.27Å; L83-I85 PolarHBondContact O-N 3.26Å; L83-L86 PolarHBondContact O-N 2.99Å; L83-V87 WeakPolarHBondContact O-CB 3.49Å; L83-V87 WeakPolarHBondContact O-CG2 3.4Å; L83-V87 PolarHBondContact O-N 3.46Å; L83-I143 HydrophobicContact CD1-CG2 3.82Å; L83-L146 HydrophobicContact CB-CD2 3.67Å; L83-L146 HydrophobicContact CB-CG 4.18Å; L83-L146 HydrophobicContact CD1-CB 4.29Å; L83-L146 HydrophobicContact CD1-CD2 4.33Å; L83-L146 HydrophobicContact CD1-CG 4.39Å; L83-L146 HydrophobicContact CD2-CG 4.19Å; L83-L146 HydrophobicContact CG-CD2 4.42Å; L83-L146 HydrophobicContact CG-CG 4.49Å; L83-I147 HydrophobicContact CD1-CB 4.2Å; L83-I147 HydrophobicContact CD2-CB 4.25Å; L83-V150 HydrophobicContact CD2-CB 4.26Å; L83-V150 HydrophobicContact CD2-CG1 4.47Å; L83-V150 HydrophobicContact CD2-CG2 3.94Å
84	L	95.1	Very high	94.3	Very high	84 Å²	84	34.4 Å²	34.4	44%	0.44	17%	0.169	S	C	.	.	H	α-helix	trans	-59.3	-41.5	172.5	-75.8	173.9	0	0	0	111.3	C80 V81 F88 M89	C80-L84 WeakPolarHBondContact O-CB 3.23Å; C80-L84 VanDerWaalsContact O-CG 3.3Å; C80-L84 WeakPolarHBondContact O-CG 3.49Å; C80-L84 PolarHBondContact O-N 3.27Å; V81-L84 PolarHBondContact O-N 2.81Å; L84-F88 HydrophobicContact CD2-CD2 3.96Å; L84-F88 HydrophobicContact CD2-CE2 4.17Å; L84-F88 WeakPolarHBondContact O-CB 3.29Å; L84-F88 PolarHBondContact O-N 3.04Å; L84-M89 PolarHBondContact O-N 3.22Å
85	I	95.6	Very high	94.3	Very high	17 Å²	17	34.1 Å²	34.1	9%	0.087	17%	0.169	C	C	.	.	I	π-helix	trans	-65.2	-48.5	177.9	-68.1	164	0	0	0	111	V46 T47 F50 V81 I82 L83 M89 V90	V46-I85 HydrophobicContact CG1-CD1 3.56Å; T47-I85 VanDerWaalsContact OG1-CG2 3.27Å; T47-I85 WeakPolarHBondContact OG1-CG2 3.26Å; F50-I85 HydrophobicContact CD2-CD1 4.24Å; V81-I85 HydrophobicContact CG1-CD1 3.7Å; V81-I85 HydrophobicContact CG1-CG1 4.4Å; V81-I85 WeakPolarHBondContact O-CD1 3.24Å; V81-I85 VanDerWaalsContact O-CG1 3.25Å; V81-I85 WeakPolarHBondContact O-CG1 3.4Å; V81-I85 PolarHBondContact O-N 3.42Å; I82-I85 PolarHBondContact O-N 3.5Å; L83-I85 VanDerWaalsContact C-N 3.27Å; L83-I85 PolarHBondContact O-N 3.26Å; I85-M89 PolarHBondContact O-N 3.39Å; I85-V90 HydrophobicContact CG2-CG2 3.69Å; I85-V90 WeakPolarHBondContact O-CB 3.41Å; I85-V90 WeakPolarHBondContact O-CG2 3.21Å; I85-V90 PolarHBondContact O-N 2.96Å
86	L	95.8	Very high	94.3	Very high	0 Å²	0	36.5 Å²	36.5	0%	0	18%	0.178	C	C	.	.	I	π-helix	trans	-75	-28.7	-173.7	-68.2	172.5	0	0	0	114.2	T47 I82 L83 P91 V150 Q387 M391 V394	T47-L86 HydrophobicContact CG2-CD2 4.22Å; I82-L86 HydrophobicContact CD1-CD1 4.4Å; I82-L86 HydrophobicContact CD1-CG 4.48Å; I82-L86 HydrophobicContact CG1-CD1 3.88Å; I82-L86 HydrophobicContact CG1-CG 4.34Å; I82-L86 WeakPolarHBondContact O-CB 3.14Å; I82-L86 VanDerWaalsContact O-CG 3.26Å; I82-L86 WeakPolarHBondContact O-CG 3.46Å; I82-L86 PolarHBondContact O-N 2.91Å; L83-L86 PolarHBondContact O-N 2.99Å; L86-P91 WeakPolarHBondContact O-CD 3.2Å; L86-P91 VanDerWaalsContact O-CG 3.29Å; L86-P91 WeakPolarHBondContact O-CG 3.46Å; L86-V150 HydrophobicContact CD1-CG1 4.32Å; L86-Q387 PolarHBondContact O-NE2 3.05Å; L86-Q387 PolarHBondContact O-OE1 3.46Å; L86-M391 HydrophobicContact CB-SD 4.08Å; L86-M391 HydrophobicContact CD1-SD 4.09Å; L86-M391 HydrophobicContact CD2-CG 4.37Å; L86-M391 HydrophobicContact CD2-SD 4.46Å; L86-M391 HydrophobicContact CG-SD 4.44Å; L86-V394 HydrophobicContact CD1-CG2 3.9Å
87	V	94.1	Very high	94.3	Very high	0 Å²	0	32 Å²	32	0%	0	16%	0.159	C	C	.	.	I	π-helix	trans	-97	-36.6	-176.6	176	0	0	0	0	111.3	L83 P91 M121 F124 W125 L146 V150	L83-V87 WeakPolarHBondContact O-CB 3.49Å; L83-V87 WeakPolarHBondContact O-CG2 3.4Å; L83-V87 PolarHBondContact O-N 3.46Å; V87-P91 WeakPolarHBondContact O-CG 3.43Å; V87-M121 HydrophobicContact CG1-CE 4.32Å; V87-M121 HydrophobicContact CG1-SD 3.78Å; V87-F124 HydrophobicContact CG1-CE1 4.37Å; V87-F124 HydrophobicContact CG2-CE1 4.31Å; V87-F124 HydrophobicContact CG2-CE2 4.34Å; V87-F124 HydrophobicContact CG2-CZ 3.87Å; V87-W125 HydrophobicContact CG1-CH2 4.19Å; V87-W125 HydrophobicContact CG1-CZ3 3.98Å; V87-L146 HydrophobicContact CB-CD1 4.02Å; V87-L146 HydrophobicContact CB-CD2 4.45Å; V87-L146 HydrophobicContact CG1-CD1 3.88Å; V87-L146 HydrophobicContact CG2-CD1 3.3Å; V87-L146 HydrophobicContact CG2-CD2 4.04Å; V87-L146 HydrophobicContact CG2-CG 3.74Å; V87-V150 HydrophobicContact CG2-CG2 4.02Å
88	F	93.9	Very high	94.2	Very high	62 Å²	62	31.8 Å²	31.8	27%	0.272	16%	0.158	S	C	.	.	I	π-helix	trans	-106.5	-62.5	-173	-60	-93.8	0	0	0	111.7	L84 F92 W117 M121 L146	L84-F88 HydrophobicContact CD2-CD2 3.96Å; L84-F88 HydrophobicContact CD2-CE2 4.17Å; L84-F88 WeakPolarHBondContact O-CB 3.29Å; L84-F88 PolarHBondContact O-N 3.04Å; F88-F92 VanDerWaalsContact O-CB 3.23Å; F88-F92 WeakPolarHBondContact O-CB 3.5Å; F88-F92 PolarHBondContact O-N 2.91Å; F88-W117 HydrophobicContact CD1-CH2 4.34Å; F88-W117 AromaticContact CD1-CZ2 3.53Å; F88-W117 HydrophobicContact CD1-CZ2 3.53Å; F88-W117 HydrophobicContact CE1-CH2 4.49Å; F88-W117 AromaticContact CE1-CZ2 3.94Å; F88-W117 HydrophobicContact CE1-CZ2 3.94Å; F88-M121 HydrophobicContact CD1-CE 4.41Å; F88-M121 HydrophobicContact CE1-CE 3.65Å; F88-M121 HydrophobicContact CE1-SD 4.4Å; F88-M121 HydrophobicContact CZ-CE 3.99Å; F88-L146 HydrophobicContact CE2-CD2 4.47Å
89	M	95.2	Very high	94	Very high	104 Å²	104	31.8 Å²	31.8	51%	0.512	16%	0.158	S	C	.	.	I	π-helix	trans	-64.8	-58.8	-170.1	-67.7	-78	-168.9	0	0	112.4	L84 I85 F92 Y93	L84-M89 PolarHBondContact O-N 3.22Å; I85-M89 PolarHBondContact O-N 3.39Å; M89-F92 PolarHBondContact O-N 3.17Å; M89-Y93 WeakPolarHBondContact O-CD2 3.18Å; M89-Y93 PolarHBondContact O-N 3.09Å; M89-Y93 HydrophobicContact SD-CE2 4.24Å
90	V	95.7	Very high	93.8	Very high	0 Å²	0	33.3 Å²	33.3	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-61.4	-49	-173.4	174.4	0	0	0	0	111.5	I43 I85 F92 Y93 I94 L383 Q387	I43-V90 HydrophobicContact CG2-CG2 3.58Å; I85-V90 HydrophobicContact CG2-CG2 3.69Å; I85-V90 WeakPolarHBondContact O-CB 3.41Å; I85-V90 WeakPolarHBondContact O-CG2 3.21Å; I85-V90 PolarHBondContact O-N 2.96Å; V90-F92 VanDerWaalsContact C-N 3.32Å; V90-F92 PolarHBondContact O-N 3.46Å; V90-Y93 PolarHBondContact O-N 3.43Å; V90-I94 HydrophobicContact CG1-CD1 3.72Å; V90-I94 HydrophobicContact CG1-CG1 4.3Å; V90-I94 VanDerWaalsContact O-CG1 3.3Å; V90-I94 WeakPolarHBondContact O-CG1 3.4Å; V90-I94 PolarHBondContact O-N 3.39Å; V90-L383 WeakPolarHBondContact CG1-O 3.1Å; V90-Q387 VanDerWaalsContact CB-OE1 3.29Å; V90-Q387 HydrophobicContact CG1-CB 3.83Å
91	P	95.9	Very high	93.4	Very high	9 Å²	9	35 Å²	35	6%	0.058	18%	0.175	C	C	.	.	H	α-helix	trans	-61.4	-37.4	178	-25.8	37.9	0	0	0	113.5	L86 V87 I94 G95 F120	L86-P91 WeakPolarHBondContact O-CD 3.2Å; L86-P91 VanDerWaalsContact O-CG 3.29Å; L86-P91 WeakPolarHBondContact O-CG 3.46Å; V87-P91 WeakPolarHBondContact O-CG 3.43Å; P91-I94 PolarHBondContact O-N 2.99Å; P91-G95 PolarHBondContact O-N 3.05Å; P91-F120 HydrophobicContact CB-CD1 3.51Å; P91-F120 HydrophobicContact CB-CD2 4.32Å; P91-F120 HydrophobicContact CB-CE1 3.52Å; P91-F120 HydrophobicContact CB-CE2 4.31Å; P91-F120 HydrophobicContact CB-CG 3.94Å; P91-F120 HydrophobicContact CB-CZ 3.93Å; P91-F120 HydrophobicContact CG-CD1 3.94Å; P91-F120 HydrophobicContact CG-CE1 3.37Å; P91-F120 HydrophobicContact CG-CE2 4.27Å; P91-F120 HydrophobicContact CG-CZ 3.56Å
92	F	95.6	Very high	93	Very high	63 Å²	63	36.9 Å²	36.9	28%	0.276	18%	0.182	S	C	.	.	H	α-helix	trans	-62.8	-47.5	175.5	177	-97.4	0	0	0	111.6	F88 M89 V90 I94 G95 Y96 W117	F88-F92 VanDerWaalsContact O-CB 3.23Å; F88-F92 WeakPolarHBondContact O-CB 3.5Å; F88-F92 PolarHBondContact O-N 2.91Å; M89-F92 PolarHBondContact O-N 3.17Å; V90-F92 VanDerWaalsContact C-N 3.32Å; V90-F92 PolarHBondContact O-N 3.46Å; F92-I94 VanDerWaalsContact C-N 3.35Å; F92-I94 PolarHBondContact O-N 3.41Å; F92-G95 PolarHBondContact O-N 3.13Å; F92-Y96 WeakPolarHBondContact O-CB 3.34Å; F92-Y96 PolarHBondContact O-N 3.39Å; F92-W117 HydrophobicContact CB-CG 4.19Å; F92-W117 HydrophobicContact CD2-CB 4.08Å; F92-W117 HydrophobicContact CD2-CG 4.14Å
93	Y	94.8	Very high	92.4	Very high	68 Å²	68	48.1 Å²	48.1	27%	0.267	23%	0.225	S	C	.	.	H	α-helix	trans	-67.3	-34.3	178.3	-78.5	-72.7	0	0	0	112.4	V39 I43 M89 V90 Y96 F97	V39-Y93 HydrophobicContact CG1-CD1 4.1Å; V39-Y93 HydrophobicContact CG1-CE1 3.64Å; I43-Y93 HydrophobicContact CD1-CD1 4.25Å; I43-Y93 HydrophobicContact CD1-CD2 3.24Å; I43-Y93 HydrophobicContact CD1-CE2 3.59Å; I43-Y93 HydrophobicContact CD1-CG 3.61Å; I43-Y93 HydrophobicContact CG1-CD2 4.49Å; M89-Y93 WeakPolarHBondContact O-CD2 3.18Å; M89-Y93 PolarHBondContact O-N 3.09Å; M89-Y93 HydrophobicContact SD-CE2 4.24Å; V90-Y93 PolarHBondContact O-N 3.43Å; Y93-Y96 PolarHBondContact O-N 3.38Å; Y93-F97 HydrophobicContact CD1-CE2 4.24Å; Y93-F97 WeakPolarHBondContact O-CD2 3.49Å; Y93-F97 PolarHBondContact O-N 2.81Å
94	I	94.1	Very high	91.7	Very high	22 Å²	22	55.7 Å²	55.7	11%	0.113	27%	0.265	C	S	.	.	H	α-helix	trans	-57.2	-52.4	171	-70.6	164.9	0	0	0	109.9	V90 P91 F92 Y96 F97 I98 V380 L383 L384 Q387	V90-I94 HydrophobicContact CG1-CD1 3.72Å; V90-I94 HydrophobicContact CG1-CG1 4.3Å; V90-I94 VanDerWaalsContact O-CG1 3.3Å; V90-I94 WeakPolarHBondContact O-CG1 3.4Å; V90-I94 PolarHBondContact O-N 3.39Å; P91-I94 PolarHBondContact O-N 2.99Å; F92-I94 VanDerWaalsContact C-N 3.35Å; F92-I94 PolarHBondContact O-N 3.41Å; I94-Y96 VanDerWaalsContact C-N 3.3Å; I94-Y96 PolarHBondContact O-N 2.97Å; I94-F97 PolarHBondContact O-N 2.9Å; I94-I98 HydrophobicContact CG2-CD1 3.63Å; I94-I98 HydrophobicContact CG2-CG1 4.43Å; I94-I98 VanDerWaalsContact O-CG1 3.25Å; I94-I98 WeakPolarHBondContact O-CG1 3.3Å; I94-I98 PolarHBondContact O-N 2.94Å; I94-V380 HydrophobicContact CG2-CG1 4.41Å; I94-L383 HydrophobicContact CD1-CB 4.25Å; I94-L383 HydrophobicContact CG1-CB 3.5Å; I94-L383 HydrophobicContact CG1-CD1 4.34Å; I94-L384 HydrophobicContact CD1-CD2 3.86Å; I94-L384 HydrophobicContact CD1-CG 4.29Å; I94-L384 HydrophobicContact CG2-CD2 4.37Å; I94-Q387 HydrophobicContact CD1-CB 4.44Å
95	G	93.1	Very high	91.1	Very high	4 Å²	4	53.5 Å²	53.5	4%	0.041	25%	0.253	C	S	.	.	H	α-helix	trans	-57.6	-43	176.7	0	0	0	0	0	112.5	P91 F92 I98 V99	P91-G95 PolarHBondContact O-N 3.05Å; F92-G95 PolarHBondContact O-N 3.13Å; G95-I98 PolarHBondContact O-N 3.31Å; G95-V99 WeakPolarHBondContact O-CG2 3.33Å; G95-V99 PolarHBondContact O-N 2.91Å
96	Y	93.2	Very high	90.4	Very high	51 Å²	51	58.3 Å²	58.3	20%	0.2	28%	0.275	C	S	.	.	H	α-helix	trans	-59.8	-48	177.5	-178.9	-90.2	0	0	0	113.5	F92 Y93 I94 V99 S100 R109 L110 S113	F92-Y96 WeakPolarHBondContact O-CB 3.34Å; F92-Y96 PolarHBondContact O-N 3.39Å; Y93-Y96 PolarHBondContact O-N 3.38Å; I94-Y96 VanDerWaalsContact C-N 3.3Å; I94-Y96 PolarHBondContact O-N 2.97Å; Y96-V99 PolarHBondContact O-N 3.38Å; Y96-S100 VanDerWaalsContact O-CB 3.31Å; Y96-S100 WeakPolarHBondContact O-CB 3.43Å; Y96-S100 PolarHBondContact O-N 3.35Å; Y96-R109 HydrophobicContact CD2-CG 4.21Å; Y96-R109 HydrophobicContact CE2-CG 4.11Å; Y96-R109 VanDerWaalsContact CZ-CZ 3.49Å; Y96-R109 PolarHBondContact OH-NE 3.14Å; Y96-R109 PolarHBondContact OH-NH1 3.33Å; Y96-R109 PolarHBondContact OH-NH2 3.08Å; Y96-L110 HydrophobicContact CD2-CD2 4.14Å; Y96-L110 HydrophobicContact CE2-CD2 3.87Å; Y96-S113 VanDerWaalsContact CA-OG 3.29Å; Y96-S113 WeakPolarHBondContact CA-OG 3.38Å
97	F	91.3	Very high	89.8	Confident	13 Å²	13	68.3 Å²	68.3	6%	0.057	32%	0.318	C	S	.	.	H	α-helix	trans	-71.3	-34.5	180	-76.6	-70.7	0	0	0	112.3	Q37 V40 Y93 I94 S100 N101 N379 V380 L383	Q37-F97 HydrophobicContact CG-CE1 3.99Å; Q37-F97 HydrophobicContact CG-CZ 3.81Å; V40-F97 HydrophobicContact CG2-CD2 4.16Å; V40-F97 HydrophobicContact CG2-CE1 4.41Å; V40-F97 HydrophobicContact CG2-CE2 3.43Å; V40-F97 VanDerWaalsContact CG2-CE2 3.43Å; V40-F97 HydrophobicContact CG2-CZ 3.6Å; Y93-F97 HydrophobicContact CD1-CE2 4.24Å; Y93-F97 WeakPolarHBondContact O-CD2 3.49Å; Y93-F97 PolarHBondContact O-N 2.81Å; I94-F97 PolarHBondContact O-N 2.9Å; F97-S100 WeakPolarHBondContact CA-OG 3.42Å; F97-S100 PolarHBondContact O-N 3.31Å; F97-S100 PolarHBondContact O-OG 3.42Å; F97-N101 PolarHBondContact O-N 2.99Å; F97-N379 HydrophobicContact CD1-CB 4.24Å; F97-N379 HydrophobicContact CG-CB 4.37Å; F97-V380 HydrophobicContact CB-CG2 3.64Å; F97-L383 HydrophobicContact CD2-CD1 3.45Å; F97-L383 VanDerWaalsContact CD2-CD1 3.45Å; F97-L383 HydrophobicContact CE2-CD1 3.9Å; F97-L383 HydrophobicContact CG-CD1 4.49Å
98	I	90.6	Very high	89.5	Confident	71 Å²	71	73.7 Å²	73.7	36%	0.364	34%	0.343	S	S	.	.	H	α-helix	trans	-59.5	-49.9	172.9	-70.4	169.1	0	0	0	110.6	I94 G95 S100 N101 L116 V380	I94-I98 HydrophobicContact CG2-CD1 3.63Å; I94-I98 HydrophobicContact CG2-CG1 4.43Å; I94-I98 VanDerWaalsContact O-CG1 3.25Å; I94-I98 WeakPolarHBondContact O-CG1 3.3Å; I94-I98 PolarHBondContact O-N 2.94Å; G95-I98 PolarHBondContact O-N 3.31Å; I98-S100 VanDerWaalsContact C-N 3.31Å; I98-S100 PolarHBondContact O-N 3.16Å; I98-N101 PolarHBondContact O-N 3.44Å; I98-L116 HydrophobicContact CG2-CD1 4.48Å; I98-V380 HydrophobicContact CD1-CG1 4.18Å; I98-V380 HydrophobicContact CG1-CG1 3.79Å; I98-V380 HydrophobicContact CG1-CG2 4.01Å
99	V	91.4	Very high	89.2	Confident	4 Å²	4	74 Å²	74	2%	0.024	34%	0.343	C	S	.	.	H	α-helix	trans	-66.9	-35.6	178.9	178.4	0	0	0	0	111.1	G95 Y96 N101 I102 L105 R109 F112 L116	G95-V99 WeakPolarHBondContact O-CG2 3.33Å; G95-V99 PolarHBondContact O-N 2.91Å; Y96-V99 PolarHBondContact O-N 3.38Å; V99-N101 PolarHBondContact O-N 3.05Å; V99-I102 PolarHBondContact O-N 3.38Å; V99-L105 HydrophobicContact CG1-CB 3.81Å; V99-L105 HydrophobicContact CG1-CD1 4.14Å; V99-R109 HydrophobicContact CB-CG 4.31Å; V99-R109 HydrophobicContact CG1-CB 4.2Å; V99-R109 HydrophobicContact CG1-CG 3.91Å; V99-F112 HydrophobicContact CG1-CB 3.93Å; V99-F112 HydrophobicContact CG2-CB 3.95Å; V99-L116 HydrophobicContact CG2-CD1 3.52Å
100	S	87.3	Confident	88.9	Confident	33 Å²	33	74.5 Å²	74.5	23%	0.231	35%	0.347	C	S	.	.	H	α-helix	trans	-62.2	-26.7	178.1	80.1	0	0	0	0	113.6	Y96 F97 I98 I102	Y96-S100 VanDerWaalsContact O-CB 3.31Å; Y96-S100 WeakPolarHBondContact O-CB 3.43Å; Y96-S100 PolarHBondContact O-N 3.35Å; F97-S100 WeakPolarHBondContact CA-OG 3.42Å; F97-S100 PolarHBondContact O-N 3.31Å; F97-S100 PolarHBondContact O-OG 3.42Å; I98-S100 VanDerWaalsContact C-N 3.31Å; I98-S100 PolarHBondContact O-N 3.16Å; S100-I102 PolarHBondContact O-N 2.89Å
101	N	85.6	Confident	88.8	Confident	88 Å²	88	80 Å²	80	47%	0.471	38%	0.376	S	S	.	.	T	Hydrogen-bonded Turn	trans	-75.1	-14	176.5	-76.3	-14.2	0	0	0	112.8	F97 I98 V99 K376	F97-N101 PolarHBondContact O-N 2.99Å; I98-N101 PolarHBondContact O-N 3.44Å; V99-N101 PolarHBondContact O-N 3.05Å; N101-K376 PolarHBondContact ND2-O 2.75Å
102	I	86.2	Confident	88.7	Confident	79 Å²	79	82.7 Å²	82.7	41%	0.405	39%	0.387	S	S	.	.			trans	-97	108.7	-179	-55.8	172.4	0	0	0	109.6	V99 S100 L104 L105	V99-I102 PolarHBondContact O-N 3.38Å; S100-I102 PolarHBondContact O-N 2.89Å; I102-L104 HydrophobicContact CG2-CB 4.28Å; I102-L104 PolarHBondContact O-N 3.07Å; I102-L105 HydrophobicContact CB-CD1 4.38Å; I102-L105 HydrophobicContact CB-CG 4.44Å; I102-L105 HydrophobicContact CD1-CD1 4.12Å; I102-L105 HydrophobicContact CG2-CB 4.45Å; I102-L105 HydrophobicContact CG2-CD1 4.14Å; I102-L105 HydrophobicContact CG2-CG 3.95Å; I102-L105 PolarHBondContact O-N 2.86Å
103	R	81.6	Confident	88.5	Confident	236 Å²	236	79.7 Å²	79.7	89%	0.891	37%	0.374	S	S	*	.	G	3₁₀ helix	trans	-55.9	-36.3	-177.7	-69.1	-178	-178.8	178.8	-1.2	113.6	L105	R103-L105 VanDerWaalsContact C-N 3.29Å; R103-L105 PolarHBondContact O-N 2.72Å
104	L	80.6	Confident	88.5	Confident	162 Å²	162	78.9 Å²	78.9	85%	0.848	38%	0.378	S	S	*	.	G	3₁₀ helix	trans	-66.6	-29.2	-176.1	-159.9	77.4	0	0	0	113	I102	I102-L104 HydrophobicContact CG2-CB 4.28Å; I102-L104 PolarHBondContact O-N 3.07Å
105	L	82.4	Confident	88.6	Confident	37 Å²	37	82.6 Å²	82.6	19%	0.194	40%	0.397	C	S	.	.	G	3₁₀ helix	trans	-97.6	8.7	-172.6	-58.2	-179.1	0	0	0	113.2	V99 I102 R103 K107 Q108 R109 F112	V99-L105 HydrophobicContact CG1-CB 3.81Å; V99-L105 HydrophobicContact CG1-CD1 4.14Å; I102-L105 HydrophobicContact CB-CD1 4.38Å; I102-L105 HydrophobicContact CB-CG 4.44Å; I102-L105 HydrophobicContact CD1-CD1 4.12Å; I102-L105 HydrophobicContact CG2-CB 4.45Å; I102-L105 HydrophobicContact CG2-CD1 4.14Å; I102-L105 HydrophobicContact CG2-CG 3.95Å; I102-L105 PolarHBondContact O-N 2.86Å; R103-L105 VanDerWaalsContact C-N 3.29Å; R103-L105 PolarHBondContact O-N 2.72Å; L105-K107 VanDerWaalsContact C-N 3.34Å; L105-K107 PolarHBondContact O-N 3.31Å; L105-Q108 CarbonylContact O-C 3.58Å; L105-Q108 PolarHBondContact O-N 3.1Å; L105-Q108 VanDerWaalsContact O-N 3.14Å; L105-R109 WeakPolarHBondContact O-CA 3.42Å; L105-R109 PolarHBondContact O-N 3.44Å; L105-F112 HydrophobicContact CB-CD2 4.38Å; L105-F112 HydrophobicContact CD1-CD1 4.39Å; L105-F112 HydrophobicContact CD1-CD2 4.36Å; L105-F112 HydrophobicContact CD1-CG 4.18Å; L105-F112 HydrophobicContact CD2-CD2 3.94Å; L105-F112 HydrophobicContact CD2-CE1 4.4Å; L105-F112 HydrophobicContact CD2-CE2 3.62Å; L105-F112 HydrophobicContact CD2-CG 4.47Å; L105-F112 HydrophobicContact CD2-CZ 3.87Å; L105-F112 HydrophobicContact CG-CD2 4.45Å
106	H	79.6	Confident	88.6	Confident	118 Å²	118	86 Å²	86	55%	0.546	41%	0.414	S	S	.	.	G	3₁₀ helix	trans	-59.4	-39.8	-171.1	-167.4	-87.9	0	0	0	113.5
107	K	82.8	Confident	88.7	Confident	211 Å²	211	86 Å²	86	92%	0.917	41%	0.414	S	S	*	.	G	3₁₀ helix	trans	-70.9	-30	179.1	-74.1	-172.4	178.2	-177.7	0	113.7	L105	L105-K107 VanDerWaalsContact C-N 3.34Å; L105-K107 PolarHBondContact O-N 3.31Å
108	Q	88.4	Confident	88.9	Confident	112 Å²	112	89.7 Å²	89.7	52%	0.523	43%	0.433	S	S	.	.	G	3₁₀ helix	trans	-110.7	21.6	-177.9	-67.4	-177.7	-10.6	0	0	112.3	L105 L110 L111 F112	L105-Q108 CarbonylContact O-C 3.58Å; L105-Q108 PolarHBondContact O-N 3.1Å; L105-Q108 VanDerWaalsContact O-N 3.14Å; Q108-L110 VanDerWaalsContact C-N 3.31Å; Q108-L110 PolarHBondContact O-N 2.85Å; Q108-L111 WeakPolarHBondContact O-CB 3.43Å; Q108-L111 PolarHBondContact O-N 2.74Å; Q108-F112 HydrophobicContact CB-CD2 3.85Å; Q108-F112 HydrophobicContact CB-CE2 3.82Å; Q108-F112 WeakPolarHBondContact O-CD2 3.15Å; Q108-F112 PolarHBondContact O-N 3.23Å
109	R	87.8	Confident	89.1	Confident	68 Å²	68	89.1 Å²	89.1	26%	0.257	43%	0.433	S	S	.	.	H	α-helix	trans	-52.7	-46.2	-171.3	176.8	176.8	59	-171.4	-2.8	112.9	Y96 V99 L105 L111 S113	Y96-R109 HydrophobicContact CD2-CG 4.21Å; Y96-R109 HydrophobicContact CE2-CG 4.11Å; Y96-R109 VanDerWaalsContact CZ-CZ 3.49Å; Y96-R109 PolarHBondContact OH-NE 3.14Å; Y96-R109 PolarHBondContact OH-NH1 3.33Å; Y96-R109 PolarHBondContact OH-NH2 3.08Å; V99-R109 HydrophobicContact CB-CG 4.31Å; V99-R109 HydrophobicContact CG1-CB 4.2Å; V99-R109 HydrophobicContact CG1-CG 3.91Å; L105-R109 WeakPolarHBondContact O-CA 3.42Å; L105-R109 PolarHBondContact O-N 3.44Å; R109-L111 PolarHBondContact O-N 3.04Å; R109-S113 WeakPolarHBondContact O-CB 3.28Å; R109-S113 PolarHBondContact O-N 3.45Å; R109-S113 PolarHBondContact O-OG 3.47Å
110	L	89.9	Confident	89.2	Confident	115 Å²	115	92 Å²	92	60%	0.602	45%	0.446	S	S	*	.	H	α-helix	trans	-63.2	-40	-179.2	-71.9	173.6	0	0	0	112.5	Y96 Q108 S113 C114	Y96-L110 HydrophobicContact CD2-CD2 4.14Å; Y96-L110 HydrophobicContact CE2-CD2 3.87Å; Q108-L110 VanDerWaalsContact C-N 3.31Å; Q108-L110 PolarHBondContact O-N 2.85Å; L110-S113 PolarHBondContact O-N 3.24Å; L110-C114 WeakPolarHBondContact O-CB 3.41Å; L110-C114 PolarHBondContact O-N 3.25Å
111	L	92.7	Very high	89.4	Confident	117 Å²	117	91.7 Å²	91.7	61%	0.613	44%	0.441	S	S	*	.	H	α-helix	trans	-63.2	-51	179.4	-175.5	73.7	0	0	0	111	Q108 R109 S113 C114 L115	Q108-L111 WeakPolarHBondContact O-CB 3.43Å; Q108-L111 PolarHBondContact O-N 2.74Å; R109-L111 PolarHBondContact O-N 3.04Å; L111-S113 VanDerWaalsContact C-N 3.3Å; L111-S113 PolarHBondContact O-N 3.34Å; L111-C114 WeakPolarHBondContact O-CB 3.36Å; L111-C114 PolarHBondContact O-N 3.36Å; L111-L115 PolarHBondContact O-N 3.16Å
112	F	92.9	Very high	89.8	Confident	64 Å²	64	93.8 Å²	93.8	28%	0.281	44%	0.443	S	S	.	.	H	α-helix	trans	-66.3	-32.6	178.3	-76.5	-78.5	0	0	0	112.6	V99 L105 Q108 L115 L116	V99-F112 HydrophobicContact CG1-CB 3.93Å; V99-F112 HydrophobicContact CG2-CB 3.95Å; L105-F112 HydrophobicContact CB-CD2 4.38Å; L105-F112 HydrophobicContact CD1-CD1 4.39Å; L105-F112 HydrophobicContact CD1-CD2 4.36Å; L105-F112 HydrophobicContact CD1-CG 4.18Å; L105-F112 HydrophobicContact CD2-CD2 3.94Å; L105-F112 HydrophobicContact CD2-CE1 4.4Å; L105-F112 HydrophobicContact CD2-CE2 3.62Å; L105-F112 HydrophobicContact CD2-CG 4.47Å; L105-F112 HydrophobicContact CD2-CZ 3.87Å; L105-F112 HydrophobicContact CG-CD2 4.45Å; Q108-F112 HydrophobicContact CB-CD2 3.85Å; Q108-F112 HydrophobicContact CB-CE2 3.82Å; Q108-F112 WeakPolarHBondContact O-CD2 3.15Å; Q108-F112 PolarHBondContact O-N 3.23Å; F112-L115 PolarHBondContact O-N 3.18Å; F112-L116 WeakPolarHBondContact O-CG 3.28Å; F112-L116 PolarHBondContact O-N 3.41Å
113	S	93.1	Very high	90	Very high	0 Å²	0	96 Å²	96	0%	0	45%	0.45	C	S	.	.	H	α-helix	trans	-65.7	-41.9	174	-52.6	0	0	0	0	111.3	Y96 R109 L110 L111 L116 W117	Y96-S113 VanDerWaalsContact CA-OG 3.29Å; Y96-S113 WeakPolarHBondContact CA-OG 3.38Å; R109-S113 WeakPolarHBondContact O-CB 3.28Å; R109-S113 PolarHBondContact O-N 3.45Å; R109-S113 PolarHBondContact O-OG 3.47Å; L110-S113 PolarHBondContact O-N 3.24Å; L111-S113 VanDerWaalsContact C-N 3.3Å; L111-S113 PolarHBondContact O-N 3.34Å; S113-L116 PolarHBondContact O-N 3.04Å; S113-W117 WeakPolarHBondContact O-CB 3.41Å; S113-W117 PolarHBondContact O-N 3.41Å
114	C	94.4	Very high	90.4	Very high	52 Å²	52	85 Å²	85	35%	0.351	41%	0.409	S	S	.	.	H	α-helix	trans	-63.5	-41.8	174.3	-169	0	0	0	0	111.2	L110 L111 W117 L118	L110-C114 WeakPolarHBondContact O-CB 3.41Å; L110-C114 PolarHBondContact O-N 3.25Å; L111-C114 WeakPolarHBondContact O-CB 3.36Å; L111-C114 PolarHBondContact O-N 3.36Å; C114-W117 PolarHBondContact O-N 2.98Å; C114-L118 WeakPolarHBondContact O-CB 3.37Å; C114-L118 WeakPolarHBondContact O-CG 3.36Å; C114-L118 PolarHBondContact O-N 3.44Å
115	L	95.1	Very high	90.8	Very high	99 Å²	99	80.1 Å²	80.1	52%	0.518	38%	0.379	S	S	.	.	H	α-helix	trans	-62.5	-43.7	176	-173.8	69.6	0	0	0	112.3	L111 F112 W117 L118 T119	L111-L115 PolarHBondContact O-N 3.16Å; F112-L115 PolarHBondContact O-N 3.18Å; L115-W117 VanDerWaalsContact C-N 3.34Å; L115-L118 PolarHBondContact O-N 3.01Å; L115-T119 WeakPolarHBondContact O-CB 3.5Å; L115-T119 PolarHBondContact O-N 3.35Å; L115-T119 PolarHBondContact O-OG1 3.25Å
116	L	94.2	Very high	91	Very high	76 Å²	76	83.4 Å²	83.4	40%	0.398	39%	0.392	S	S	.	.	H	α-helix	trans	-63.1	-41.7	174.6	-76.6	176.1	0	0	0	111.6	I98 V99 F112 S113 T119 F120	I98-L116 HydrophobicContact CG2-CD1 4.48Å; V99-L116 HydrophobicContact CG2-CD1 3.52Å; F112-L116 WeakPolarHBondContact O-CG 3.28Å; F112-L116 PolarHBondContact O-N 3.41Å; S113-L116 PolarHBondContact O-N 3.04Å; L116-T119 WeakPolarHBondContact O-CB 3.25Å; L116-T119 PolarHBondContact O-N 2.82Å; L116-F120 PolarHBondContact O-N 2.84Å
117	W	95.1	Very high	91.1	Very high	51 Å²	51	81 Å²	81	19%	0.193	38%	0.383	C	S	.	.	H	α-helix	trans	-64.7	-44.2	176.5	176	74.6	0	0	0	112.1	F88 F92 S113 C114 L115 T119 F120 M121	F88-W117 HydrophobicContact CD1-CH2 4.34Å; F88-W117 AromaticContact CD1-CZ2 3.53Å; F88-W117 HydrophobicContact CD1-CZ2 3.53Å; F88-W117 HydrophobicContact CE1-CH2 4.49Å; F88-W117 AromaticContact CE1-CZ2 3.94Å; F88-W117 HydrophobicContact CE1-CZ2 3.94Å; F92-W117 HydrophobicContact CB-CG 4.19Å; F92-W117 HydrophobicContact CD2-CB 4.08Å; F92-W117 HydrophobicContact CD2-CG 4.14Å; S113-W117 WeakPolarHBondContact O-CB 3.41Å; S113-W117 PolarHBondContact O-N 3.41Å; C114-W117 PolarHBondContact O-N 2.98Å; L115-W117 VanDerWaalsContact C-N 3.34Å; W117-T119 VanDerWaalsContact C-N 3.29Å; W117-T119 PolarHBondContact O-N 2.9Å; W117-F120 WeakPolarHBondContact O-CB 3.48Å; W117-F120 PolarHBondContact O-N 2.76Å; W117-M121 HydrophobicContact CD2-CG 4.06Å; W117-M121 HydrophobicContact CE3-CG 4.49Å; W117-M121 HydrophobicContact CH2-CE 4.42Å; W117-M121 HydrophobicContact CH2-CG 3.99Å; W117-M121 HydrophobicContact CZ2-CE 3.99Å; W117-M121 HydrophobicContact CZ2-CG 3.45Å; W117-M121 VanDerWaalsContact CZ2-CG 3.45Å; W117-M121 HydrophobicContact CZ2-SD 3.76Å; W117-M121 HydrophobicContact CZ3-CG 4.48Å; W117-M121 WeakPolarHBondContact O-CG 3.49Å; W117-M121 PolarHBondContact O-N 3.25Å
118	L	95	Very high	90.8	Very high	90 Å²	90	71 Å²	71	47%	0.471	34%	0.34	S	S	.	.	H	α-helix	trans	-61.5	-38.8	174	-74.2	172.9	0	0	0	111.8	C114 L115 M121 Y122	C114-L118 WeakPolarHBondContact O-CB 3.37Å; C114-L118 WeakPolarHBondContact O-CG 3.36Å; C114-L118 PolarHBondContact O-N 3.44Å; L115-L118 PolarHBondContact O-N 3.01Å; L118-M121 PolarHBondContact O-N 3.06Å; L118-Y122 PolarHBondContact O-N 2.88Å
119	T	94.4	Very high	90.3	Very high	59 Å²	59	70.4 Å²	70.4	36%	0.362	34%	0.34	S	S	.	.	H	α-helix	trans	-62.5	-46.7	174.5	-56.7	0	0	0	0	110.9	L115 L116 W117 M121 Y122 F123	L115-T119 WeakPolarHBondContact O-CB 3.5Å; L115-T119 PolarHBondContact O-N 3.35Å; L115-T119 PolarHBondContact O-OG1 3.25Å; L116-T119 WeakPolarHBondContact O-CB 3.25Å; L116-T119 PolarHBondContact O-N 2.82Å; W117-T119 VanDerWaalsContact C-N 3.29Å; W117-T119 PolarHBondContact O-N 2.9Å; T119-M121 PolarHBondContact O-N 2.76Å; T119-Y122 PolarHBondContact O-N 2.75Å; T119-F123 HydrophobicContact CG2-CD2 3.82Å; T119-F123 HydrophobicContact CG2-CE2 3.59Å; T119-F123 WeakPolarHBondContact O-CD2 3.49Å; T119-F123 PolarHBondContact O-N 2.89Å
120	F	93.7	Very high	89.7	Confident	66 Å²	66	72.1 Å²	72.1	29%	0.289	36%	0.359	S	S	.	.	H	α-helix	trans	-58.1	-47.1	173.9	168.9	-92.7	0	0	0	111.5	P91 L116 W117 Y122 F123 F124	P91-F120 HydrophobicContact CB-CD1 3.51Å; P91-F120 HydrophobicContact CB-CD2 4.32Å; P91-F120 HydrophobicContact CB-CE1 3.52Å; P91-F120 HydrophobicContact CB-CE2 4.31Å; P91-F120 HydrophobicContact CB-CG 3.94Å; P91-F120 HydrophobicContact CB-CZ 3.93Å; P91-F120 HydrophobicContact CG-CD1 3.94Å; P91-F120 HydrophobicContact CG-CE1 3.37Å; P91-F120 HydrophobicContact CG-CE2 4.27Å; P91-F120 HydrophobicContact CG-CZ 3.56Å; L116-F120 PolarHBondContact O-N 2.84Å; W117-F120 WeakPolarHBondContact O-CB 3.48Å; W117-F120 PolarHBondContact O-N 2.76Å; F120-Y122 VanDerWaalsContact C-N 3.34Å; F120-Y122 PolarHBondContact O-N 3.02Å; F120-F123 PolarHBondContact O-N 2.9Å; F120-F124 HydrophobicContact CE1-CB 4.28Å; F120-F124 HydrophobicContact CE1-CD2 4.48Å; F120-F124 HydrophobicContact CZ-CB 4.36Å; F120-F124 HydrophobicContact CZ-CD2 4.08Å; F120-F124 HydrophobicContact CZ-CG 4.5Å; F120-F124 VanDerWaalsContact O-CB 3.29Å; F120-F124 WeakPolarHBondContact O-CB 3.31Å; F120-F124 PolarHBondContact O-N 3.06Å
121	M	92.4	Very high	88.8	Confident	25 Å²	25	68.1 Å²	68.1	12%	0.123	34%	0.337	C	S	.	.	H	α-helix	trans	-59.4	-44.2	177.4	-72.2	-67.6	-72.9	0	0	111.3	V87 F88 W117 L118 T119 F123 F124 W125	V87-M121 HydrophobicContact CG1-CE 4.32Å; V87-M121 HydrophobicContact CG1-SD 3.78Å; F88-M121 HydrophobicContact CD1-CE 4.41Å; F88-M121 HydrophobicContact CE1-CE 3.65Å; F88-M121 HydrophobicContact CE1-SD 4.4Å; F88-M121 HydrophobicContact CZ-CE 3.99Å; W117-M121 HydrophobicContact CD2-CG 4.06Å; W117-M121 HydrophobicContact CE3-CG 4.49Å; W117-M121 HydrophobicContact CH2-CE 4.42Å; W117-M121 HydrophobicContact CH2-CG 3.99Å; W117-M121 HydrophobicContact CZ2-CE 3.99Å; W117-M121 HydrophobicContact CZ2-CG 3.45Å; W117-M121 VanDerWaalsContact CZ2-CG 3.45Å; W117-M121 HydrophobicContact CZ2-SD 3.76Å; W117-M121 HydrophobicContact CZ3-CG 4.48Å; W117-M121 WeakPolarHBondContact O-CG 3.49Å; W117-M121 PolarHBondContact O-N 3.25Å; L118-M121 PolarHBondContact O-N 3.06Å; T119-M121 PolarHBondContact O-N 2.76Å; M121-F123 PolarHBondContact O-N 2.86Å; M121-F124 PolarHBondContact O-N 3.39Å; M121-W125 HydrophobicContact CE-CE3 3.77Å; M121-W125 HydrophobicContact CE-CH2 3.54Å; M121-W125 HydrophobicContact CE-CZ2 4.49Å; M121-W125 HydrophobicContact CE-CZ3 3.1Å; M121-W125 WeakPolarHBondContact O-CB 3.02Å; M121-W125 PolarHBondContact O-N 3.12Å; M121-W125 HydrophobicContact SD-CE3 4.23Å; M121-W125 HydrophobicContact SD-CH2 4.48Å; M121-W125 HydrophobicContact SD-CZ3 3.62Å
122	Y	92.6	Very high	87.5	Confident	132 Å²	132	65.9 Å²	65.9	52%	0.518	33%	0.33	S	S	.	.	H	α-helix	trans	-57.3	-49.7	175	173.6	-96.1	0	0	0	111.9	L118 T119 F120 W125 K126	L118-Y122 PolarHBondContact O-N 2.88Å; T119-Y122 PolarHBondContact O-N 2.75Å; F120-Y122 VanDerWaalsContact C-N 3.34Å; F120-Y122 PolarHBondContact O-N 3.02Å; Y122-W125 PolarHBondContact O-N 3.09Å; Y122-K126 HydrophobicContact CE1-CD 4Å; Y122-K126 WeakPolarHBondContact O-CB 3.42Å; Y122-K126 PolarHBondContact O-N 3.26Å; Y122-K126 PolarHBondContact OH-NZ 3.24Å
123	F	91.8	Very high	86	Confident	126 Å²	126	64 Å²	64	55%	0.553	32%	0.322	S	S	*	.	H	α-helix	trans	-66.3	-39.4	178.5	-77.1	-67	0	0	0	112.7	T119 F120 M121 W125 K126 L127	T119-F123 HydrophobicContact CG2-CD2 3.82Å; T119-F123 HydrophobicContact CG2-CE2 3.59Å; T119-F123 WeakPolarHBondContact O-CD2 3.49Å; T119-F123 PolarHBondContact O-N 2.89Å; F120-F123 PolarHBondContact O-N 2.9Å; M121-F123 PolarHBondContact O-N 2.86Å; F123-W125 VanDerWaalsContact C-N 3.31Å; F123-W125 PolarHBondContact O-N 3.42Å; F123-K126 PolarHBondContact O-N 3.26Å; F123-L127 WeakPolarHBondContact O-CB 3.36Å; F123-L127 PolarHBondContact O-N 2.86Å
124	F	90.6	Very high	84.3	Confident	6 Å²	6	68.7 Å²	68.7	3%	0.026	35%	0.347	C	S	.	.	H	α-helix	trans	-62.7	-39.3	175.8	-178.2	-84.8	0	0	0	111.3	V87 F120 M121 L146 R149 V150 I153	V87-F124 HydrophobicContact CG1-CE1 4.37Å; V87-F124 HydrophobicContact CG2-CE1 4.31Å; V87-F124 HydrophobicContact CG2-CE2 4.34Å; V87-F124 HydrophobicContact CG2-CZ 3.87Å; F120-F124 HydrophobicContact CE1-CB 4.28Å; F120-F124 HydrophobicContact CE1-CD2 4.48Å; F120-F124 HydrophobicContact CZ-CB 4.36Å; F120-F124 HydrophobicContact CZ-CD2 4.08Å; F120-F124 HydrophobicContact CZ-CG 4.5Å; F120-F124 VanDerWaalsContact O-CB 3.29Å; F120-F124 WeakPolarHBondContact O-CB 3.31Å; F120-F124 PolarHBondContact O-N 3.06Å; M121-F124 PolarHBondContact O-N 3.39Å; F124-L146 HydrophobicContact CE1-CD1 3.59Å; F124-L146 HydrophobicContact CZ-CD1 3.85Å; F124-R149 HydrophobicContact CE1-CB 3.87Å; F124-R149 HydrophobicContact CE1-CG 4.44Å; F124-R149 HydrophobicContact CE2-CB 4.17Å; F124-R149 HydrophobicContact CZ-CB 3.55Å; F124-R149 PolarHBondContact O-NH1 3.34Å; F124-V150 HydrophobicContact CE2-CG2 4.16Å; F124-V150 HydrophobicContact CZ-CG2 3.97Å; F124-I153 HydrophobicContact CD2-CD1 4.04Å; F124-I153 HydrophobicContact CE2-CD1 4.05Å
125	W	87.6	Confident	82.5	Confident	58 Å²	58	67.9 Å²	67.9	22%	0.22	34%	0.342	C	S	.	.	H	α-helix	trans	-72.4	-28.3	173.6	-100.1	-103.4	0	0	0	113.3	V87 M121 Y122 F123 D129 L141 L146 R149	V87-W125 HydrophobicContact CG1-CH2 4.19Å; V87-W125 HydrophobicContact CG1-CZ3 3.98Å; M121-W125 HydrophobicContact CE-CE3 3.77Å; M121-W125 HydrophobicContact CE-CH2 3.54Å; M121-W125 HydrophobicContact CE-CZ2 4.49Å; M121-W125 HydrophobicContact CE-CZ3 3.1Å; M121-W125 WeakPolarHBondContact O-CB 3.02Å; M121-W125 PolarHBondContact O-N 3.12Å; M121-W125 HydrophobicContact SD-CE3 4.23Å; M121-W125 HydrophobicContact SD-CH2 4.48Å; M121-W125 HydrophobicContact SD-CZ3 3.62Å; Y122-W125 PolarHBondContact O-N 3.09Å; F123-W125 VanDerWaalsContact C-N 3.31Å; F123-W125 PolarHBondContact O-N 3.42Å; W125-D129 VanDerWaalsContact O-OD1 3.05Å; W125-L141 HydrophobicContact CH2-CD2 4.32Å; W125-L141 HydrophobicContact CZ2-CD2 3.77Å; W125-L146 HydrophobicContact CH2-CD1 4.06Å; W125-R149 VanDerWaalsContact O-CZ 3.26Å; W125-R149 PolarHBondContact O-NH1 3.46Å; W125-R149 PolarHBondContact O-NH2 3.36Å; W125-R149 VanDerWaalsContact O-NH2 3.09Å
126	K	87.1	Confident	80.7	Confident	107 Å²	107	69.5 Å²	69.5	47%	0.465	36%	0.358	S	S	.	.	H	α-helix	trans	-79.4	-30.5	174.8	-163.9	169.8	-171.8	172.6	0	113.1	Y122 F123 G128 D129 P130	Y122-K126 HydrophobicContact CE1-CD 4Å; Y122-K126 WeakPolarHBondContact O-CB 3.42Å; Y122-K126 PolarHBondContact O-N 3.26Å; Y122-K126 PolarHBondContact OH-NZ 3.24Å; F123-K126 PolarHBondContact O-N 3.26Å; K126-G128 VanDerWaalsContact C-N 3.26Å; K126-G128 PolarHBondContact O-N 3.48Å; K126-D129 PolarHBondContact O-N 3.44Å; K126-P130 WeakPolarHBondContact O-CD 3.37Å
127	L	82.7	Confident	79	Confident	68 Å²	68	74.1 Å²	74.1	36%	0.356	38%	0.375	S	S	.	.	H	α-helix	trans	-63.3	-30.5	-176.3	-173.7	146.7	0	0	0	112.9	F123 P130 F131 V152 I153	F123-L127 WeakPolarHBondContact O-CB 3.36Å; F123-L127 PolarHBondContact O-N 2.86Å; L127-P130 WeakPolarHBondContact O-CD 2.93Å; L127-F131 HydrophobicContact CD2-CE2 4.05Å; L127-F131 WeakPolarHBondContact O-CD2 3.17Å; L127-F131 WeakPolarHBondContact O-CE2 3.48Å; L127-V152 HydrophobicContact CD2-CG1 4.39Å; L127-I153 HydrophobicContact CD1-CD1 4.24Å; L127-I153 HydrophobicContact CD1-CG1 4.19Å; L127-I153 HydrophobicContact CD2-CD1 4.29Å; L127-I153 HydrophobicContact CD2-CG1 3.94Å
128	G	75.6	Confident	77.3	Confident	1 Å²	1	75 Å²	75	1%	0.01	38%	0.382	C	S	.	.	T	Hydrogen-bonded Turn	trans	-82.3	-14.2	179.5	0	0	0	0	0	115.6	K126 F131	K126-G128 VanDerWaalsContact C-N 3.26Å; K126-G128 PolarHBondContact O-N 3.48Å; G128-F131 PolarHBondContact O-N 3.48Å
129	D	77.6	Confident	75.8	Confident	98 Å²	98	73.2 Å²	73.2	52%	0.524	39%	0.385	S	S	.	.	T	Hydrogen-bonded Turn	trans	-67.7	-35.6	-175.4	-57.3	-16.5	0	0	0	114	W125 K126 F131 R149	W125-D129 VanDerWaalsContact O-OD1 3.05Å; K126-D129 PolarHBondContact O-N 3.44Å; D129-F131 PolarHBondContact O-N 3.08Å; D129-R149 IonicContact OD1-NH2 3.26Å; D129-R149 PolarHBondContact OD1-NH2 2.86Å
130	P	74.8	Confident	74.6	Confident	104 Å²	104	76.6 Å²	76.6	68%	0.675	40%	0.399	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70	-12	175.8	-20.4	34	0	0	0	114.4	K126 L127	K126-P130 WeakPolarHBondContact O-CD 3.37Å; L127-P130 WeakPolarHBondContact O-CD 2.93Å
131	F	70.9	Confident	73.5	Confident	31 Å²	31	80 Å²	80	14%	0.136	42%	0.419	C	S	.	.	S	Bend	trans	-102.7	145.3	-171.5	-60.7	-62.5	0	0	0	111.1	L127 G128 D129 I133 V152 F423 W427	L127-F131 HydrophobicContact CD2-CE2 4.05Å; L127-F131 WeakPolarHBondContact O-CD2 3.17Å; L127-F131 WeakPolarHBondContact O-CE2 3.48Å; G128-F131 PolarHBondContact O-N 3.48Å; D129-F131 PolarHBondContact O-N 3.08Å; F131-I133 HydrophobicContact CB-CB 4.5Å; F131-I133 HydrophobicContact CB-CD1 3.35Å; F131-I133 HydrophobicContact CB-CG1 3.59Å; F131-I133 HydrophobicContact CD2-CD1 4.2Å; F131-I133 HydrophobicContact CG-CD1 4.1Å; F131-I133 PolarHBondContact O-N 3.33Å; F131-V152 HydrophobicContact CD2-CG1 4.22Å; F131-V152 HydrophobicContact CD2-CG2 4.22Å; F131-V152 HydrophobicContact CE1-CG1 4.37Å; F131-V152 HydrophobicContact CE2-CB 4.5Å; F131-V152 HydrophobicContact CE2-CG1 3.64Å; F131-V152 HydrophobicContact CE2-CG2 4.45Å; F131-V152 HydrophobicContact CG-CG2 4.49Å; F131-V152 HydrophobicContact CZ-CG1 3.71Å; F131-F423 HydrophobicContact CB-CZ 4.17Å; F131-F423 HydrophobicContact CD1-CE1 4.18Å; F131-F423 AromaticContact CD1-CE2 3.69Å; F131-F423 HydrophobicContact CD1-CE2 3.69Å; F131-F423 AromaticContact CD1-CZ 3.2Å; F131-F423 HydrophobicContact CD1-CZ 3.2Å; F131-F423 HydrophobicContact CE1-CE2 4.3Å; F131-F423 AromaticContact CE1-CZ 3.73Å; F131-F423 HydrophobicContact CE1-CZ 3.73Å; F131-F423 HydrophobicContact CG-CE1 4.47Å; F131-F423 AromaticContact CG-CZ 3.88Å; F131-F423 HydrophobicContact CG-CZ 3.88Å; F131-W427 HydrophobicContact CE1-CD2 4.42Å; F131-W427 HydrophobicContact CE1-CE3 4.09Å; F131-W427 AromaticContact CE1-CH2 3.72Å; F131-W427 HydrophobicContact CE1-CH2 3.72Å; F131-W427 HydrophobicContact CE1-CZ2 4.06Å; F131-W427 AromaticContact CE1-CZ3 3.74Å; F131-W427 HydrophobicContact CE1-CZ3 3.74Å; F131-W427 AromaticContact CZ-CH2 3.9Å; F131-W427 HydrophobicContact CZ-CH2 3.9Å; F131-W427 AromaticContact CZ-CZ2 3.94Å; F131-W427 HydrophobicContact CZ-CZ2 3.94Å; F131-W427 HydrophobicContact CZ-CZ3 4.38Å
132	P	65.1	Low	73	Confident	70 Å²	70	79.9 Å²	79.9	46%	0.455	42%	0.421	S	S	.	.	T	Hydrogen-bonded Turn	trans	-74.5	62.3	178.6	33.6	-36.7	0	0	0	111	Q420 F423	P132-Q420 PolarHBondContact O-OE1 2.61Å; P132-F423 HydrophobicContact CG-CD2 3.98Å; P132-F423 HydrophobicContact CG-CG 4.31Å
133	I	62.8	Low	72.5	Confident	24 Å²	24	76.4 Å²	76.4	12%	0.123	41%	0.411	C	S	.	.	T	Hydrogen-bonded Turn	trans	-108.6	-24.2	-172.5	-68	175.7	0	0	0	111	F131 S135 S148 V152	F131-I133 HydrophobicContact CB-CB 4.5Å; F131-I133 HydrophobicContact CB-CD1 3.35Å; F131-I133 HydrophobicContact CB-CG1 3.59Å; F131-I133 HydrophobicContact CD2-CD1 4.2Å; F131-I133 HydrophobicContact CG-CD1 4.1Å; F131-I133 PolarHBondContact O-N 3.33Å; I133-S135 PolarHBondContact O-N 3.47Å; I133-S135 VanDerWaalsContact O-N 3.14Å; I133-S148 WeakPolarHBondContact CG2-OG 3.29Å; I133-V152 HydrophobicContact CD1-CG2 3.79Å
134	L	57.2	Low	72	Confident	100 Å²	100	72.5 Å²	72.5	52%	0.524	40%	0.395	S	S	.	.			trans	-81.2	98.4	-175.9	-72.7	114.1	0	0	0	110.8	P136	L134-P136 WeakPolarHBondContact O-CD 3.3Å
135	S	56.9	Low	71.7	Confident	34 Å²	34	73.2 Å²	73.2	24%	0.238	40%	0.398	C	S	.	.			trans	-72.6	121.6	152.3	-176.6	0	0	0	0	107.8	I133 K137 H138	I133-S135 PolarHBondContact O-N 3.47Å; I133-S135 VanDerWaalsContact O-N 3.14Å; S135-K137 PolarHBondContact O-N 2.88Å; S135-H138 PolarHBondContact O-N 3.36Å
136	P	56.9	Low	71.7	Confident	133 Å²	133	71.6 Å²	71.6	86%	0.864	39%	0.393	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.1	-1.5	-179.7	24.1	-31.7	0	0	0	113.7	L134	L134-P136 WeakPolarHBondContact O-CD 3.3Å
137	K	57.6	Low	71.7	Confident	174 Å²	174	66.6 Å²	66.6	76%	0.757	37%	0.372	S	S	*	.	T	Hydrogen-bonded Turn	trans	-87.3	-10.8	-178.6	-62.6	-175.7	179.6	177.4	0	114.2	S135	S135-K137 PolarHBondContact O-N 2.88Å
138	H	60.3	Low	71.9	Confident	70 Å²	70	63.3 Å²	63.3	32%	0.324	36%	0.355	S	S	.	.	S	Bend	trans	-114.4	139.5	-173.1	-62.7	126.1	0	0	0	113.3	S135 E144 Q145	S135-H138 PolarHBondContact O-N 3.36Å; H138-E144 IonicContact CE1-OE1 3.66Å; H138-E144 IonicContact CE1-OE2 2.95Å; H138-E144 PolarHBondContact CE1-OE2 2.85Å; H138-E144 IonicContact CG-OE2 3.78Å; H138-E144 IonicContact ND1-OE2 2.87Å; H138-E144 PolarHBondContact ND1-OE2 3.25Å; H138-E144 IonicContact NE2-OE1 3.98Å; H138-E144 IonicContact NE2-OE2 3.85Å; H138-Q145 PolarHBondContact O-NE2 2.9Å; H138-Q145 VanDerWaalsContact O-NE2 3.15Å
139	G	64.4	Low	72.6	Confident	52 Å²	52	63.8 Å²	63.8	54%	0.536	36%	0.356	S	S	.	.			trans	-64.5	161.2	178.2	0	0	0	0	0	113.7	L141 S142 Q145	G139-L141 PolarHBondContact O-N 3.33Å; G139-S142 WeakPolarHBondContact O-CB 3.46Å; G139-S142 PolarHBondContact O-N 3.12Å; G139-S142 PolarHBondContact O-OG 3.33Å; G139-Q145 PolarHBondContact O-NE2 3.24Å; G139-Q145 PolarHBondContact O-OE1 3.05Å; G139-Q145 VanDerWaalsContact O-OE1 3.06Å
140	I	67.8	Low	73.3	Confident	130 Å²	130	59.1 Å²	59.1	67%	0.667	33%	0.331	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.3	-21	-171.9	-56.3	168.1	0	0	0	114	Q145	I140-Q145 PolarHBondContact O-OE1 3.08Å
141	L	70.7	Confident	74.1	Confident	136 Å²	136	54.2 Å²	54.2	71%	0.712	30%	0.299	S	S	*	.	T	Hydrogen-bonded Turn	trans	-119.2	26.7	-179.4	-66.9	174.5	0	0	0	112.7	W125 G139	W125-L141 HydrophobicContact CH2-CD2 4.32Å; W125-L141 HydrophobicContact CZ2-CD2 3.77Å; G139-L141 PolarHBondContact O-N 3.33Å
142	S	81.3	Confident	75	Confident	23 Å²	23	52.9 Å²	52.9	16%	0.161	29%	0.293	C	S	.	.			trans	-67.2	145.2	175.8	53.8	0	0	0	0	111.7	G139 E144 Q145 L146	G139-S142 WeakPolarHBondContact O-CB 3.46Å; G139-S142 PolarHBondContact O-N 3.12Å; G139-S142 PolarHBondContact O-OG 3.33Å; S142-E144 PolarHBondContact O-N 3.4Å; S142-Q145 PolarHBondContact O-N 3.46Å; S142-Q145 VanDerWaalsContact O-N 3.16Å; S142-Q145 WeakPolarHBondContact OG-CB 3.46Å; S142-Q145 VanDerWaalsContact OG-CG 3.24Å; S142-Q145 WeakPolarHBondContact OG-CG 3.32Å; S142-L146 PolarHBondContact O-N 3.3Å; S142-L146 VanDerWaalsContact O-N 3.17Å
143	I	82.4	Confident	76.3	Confident	59 Å²	59	51.7 Å²	51.7	30%	0.303	28%	0.283	S	S	.	.	H	α-helix	trans	-55.2	-39	176.8	-69.1	171.4	0	0	0	110.4	L83 L146 I147	L83-I143 HydrophobicContact CD1-CG2 3.82Å; I143-L146 PolarHBondContact O-N 3.38Å; I143-I147 WeakPolarHBondContact O-CB 3.36Å; I143-I147 VanDerWaalsContact O-CG2 3.23Å; I143-I147 WeakPolarHBondContact O-CG2 3.38Å; I143-I147 PolarHBondContact O-N 2.91Å
144	E	81.9	Confident	77.8	Confident	45 Å²	45	50.5 Å²	50.5	21%	0.21	28%	0.277	C	S	.	.	H	α-helix	trans	-61.4	-43.4	178	-59.9	-175.4	-176.9	0	0	113.4	H138 S142 L146 I147 S148 G417	H138-E144 IonicContact CE1-OE1 3.66Å; H138-E144 IonicContact CE1-OE2 2.95Å; H138-E144 PolarHBondContact CE1-OE2 2.85Å; H138-E144 IonicContact CG-OE2 3.78Å; H138-E144 IonicContact ND1-OE2 2.87Å; H138-E144 PolarHBondContact ND1-OE2 3.25Å; H138-E144 IonicContact NE2-OE1 3.98Å; H138-E144 IonicContact NE2-OE2 3.85Å; S142-E144 PolarHBondContact O-N 3.4Å; E144-L146 VanDerWaalsContact C-N 3.29Å; E144-L146 PolarHBondContact O-N 3.46Å; E144-I147 VanDerWaalsContact O-CG2 3.26Å; E144-I147 WeakPolarHBondContact O-CG2 3.31Å; E144-S148 WeakPolarHBondContact O-CB 3.31Å; E144-S148 PolarHBondContact O-N 3.08Å; E144-S148 PolarHBondContact O-OG 3.45Å; E144-G417 VanDerWaalsContact OE1-CA 3.28Å; E144-G417 WeakPolarHBondContact OE1-CA 3.33Å
145	Q	83.6	Confident	79.4	Confident	21 Å²	21	45.8 Å²	45.8	10%	0.098	25%	0.252	C	S	.	.	H	α-helix	trans	-69.1	-31.2	176.8	-75.1	178.3	5.2	0	0	112.1	H138 G139 I140 S142 S148 R149	H138-Q145 PolarHBondContact O-NE2 2.9Å; H138-Q145 VanDerWaalsContact O-NE2 3.15Å; G139-Q145 PolarHBondContact O-NE2 3.24Å; G139-Q145 PolarHBondContact O-OE1 3.05Å; G139-Q145 VanDerWaalsContact O-OE1 3.06Å; I140-Q145 PolarHBondContact O-OE1 3.08Å; S142-Q145 PolarHBondContact O-N 3.46Å; S142-Q145 VanDerWaalsContact O-N 3.16Å; S142-Q145 WeakPolarHBondContact OG-CB 3.46Å; S142-Q145 VanDerWaalsContact OG-CG 3.24Å; S142-Q145 WeakPolarHBondContact OG-CG 3.32Å; Q145-S148 VanDerWaalsContact CA-OG 3.27Å; Q145-S148 WeakPolarHBondContact CA-OG 3.3Å; Q145-S148 PolarHBondContact O-OG 3.5Å; Q145-R149 VanDerWaalsContact O-CD 3.3Å; Q145-R149 WeakPolarHBondContact O-CD 3.48Å; Q145-R149 VanDerWaalsContact O-CG 3.29Å; Q145-R149 WeakPolarHBondContact O-CG 3.32Å; Q145-R149 PolarHBondContact O-N 3.39Å
146	L	87.8	Confident	81.1	Confident	23 Å²	23	45.7 Å²	45.7	12%	0.12	25%	0.25	C	S	.	.	H	α-helix	trans	-76.6	-47.9	-179.8	-164.2	56.1	0	0	0	111.6	L83 V87 F88 F124 W125 S142 I143 E144 S148 R149 V150	L83-L146 HydrophobicContact CB-CD2 3.67Å; L83-L146 HydrophobicContact CB-CG 4.18Å; L83-L146 HydrophobicContact CD1-CB 4.29Å; L83-L146 HydrophobicContact CD1-CD2 4.33Å; L83-L146 HydrophobicContact CD1-CG 4.39Å; L83-L146 HydrophobicContact CD2-CG 4.19Å; L83-L146 HydrophobicContact CG-CD2 4.42Å; L83-L146 HydrophobicContact CG-CG 4.49Å; V87-L146 HydrophobicContact CB-CD1 4.02Å; V87-L146 HydrophobicContact CB-CD2 4.45Å; V87-L146 HydrophobicContact CG1-CD1 3.88Å; V87-L146 HydrophobicContact CG2-CD1 3.3Å; V87-L146 HydrophobicContact CG2-CD2 4.04Å; V87-L146 HydrophobicContact CG2-CG 3.74Å; F88-L146 HydrophobicContact CE2-CD2 4.47Å; F124-L146 HydrophobicContact CE1-CD1 3.59Å; F124-L146 HydrophobicContact CZ-CD1 3.85Å; W125-L146 HydrophobicContact CH2-CD1 4.06Å; S142-L146 PolarHBondContact O-N 3.3Å; S142-L146 VanDerWaalsContact O-N 3.17Å; I143-L146 PolarHBondContact O-N 3.38Å; E144-L146 VanDerWaalsContact C-N 3.29Å; E144-L146 PolarHBondContact O-N 3.46Å; L146-S148 VanDerWaalsContact C-N 3.28Å; L146-S148 PolarHBondContact O-N 3.05Å; L146-R149 PolarHBondContact O-N 3.02Å; L146-V150 WeakPolarHBondContact O-CB 3.37Å; L146-V150 WeakPolarHBondContact O-CG2 3.49Å; L146-V150 PolarHBondContact O-N 3.35Å
147	I	88.3	Confident	82.7	Confident	2 Å²	2	41.6 Å²	41.6	1%	0.01	22%	0.221	C	C	.	.	H	α-helix	trans	-64.2	-34.8	178	-168.2	159.9	0	0	0	112	L79 L83 I143 E144 V150 G151 V394 L398 L416 L419	L79-I147 HydrophobicContact CD1-CD1 4.3Å; L79-I147 HydrophobicContact CD2-CD1 3.8Å; L83-I147 HydrophobicContact CD1-CB 4.2Å; L83-I147 HydrophobicContact CD2-CB 4.25Å; I143-I147 WeakPolarHBondContact O-CB 3.36Å; I143-I147 VanDerWaalsContact O-CG2 3.23Å; I143-I147 WeakPolarHBondContact O-CG2 3.38Å; I143-I147 PolarHBondContact O-N 2.91Å; E144-I147 VanDerWaalsContact O-CG2 3.26Å; E144-I147 WeakPolarHBondContact O-CG2 3.31Å; I147-V150 PolarHBondContact O-N 3.08Å; I147-G151 WeakPolarHBondContact O-CA 3.3Å; I147-G151 PolarHBondContact O-N 3.03Å; I147-V394 HydrophobicContact CD1-CG1 4.34Å; I147-V394 HydrophobicContact CG1-CG1 3.94Å; I147-L398 HydrophobicContact CD1-CD2 4.28Å; I147-L398 HydrophobicContact CG1-CD2 4.3Å; I147-L416 HydrophobicContact CD1-CD2 3.22Å; I147-L416 HydrophobicContact CG1-CD2 4.4Å; I147-L419 HydrophobicContact CG2-CD1 3.95Å
148	S	86.8	Confident	84.2	Confident	0 Å²	0	35.3 Å²	35.3	0%	0	20%	0.195	C	C	.	.	H	α-helix	trans	-65.6	-45.8	179.6	47.2	0	0	0	0	112.3	I133 E144 Q145 L146 G151 V152 Y424	I133-S148 WeakPolarHBondContact CG2-OG 3.29Å; E144-S148 WeakPolarHBondContact O-CB 3.31Å; E144-S148 PolarHBondContact O-N 3.08Å; E144-S148 PolarHBondContact O-OG 3.45Å; Q145-S148 VanDerWaalsContact CA-OG 3.27Å; Q145-S148 WeakPolarHBondContact CA-OG 3.3Å; Q145-S148 PolarHBondContact O-OG 3.5Å; L146-S148 VanDerWaalsContact C-N 3.28Å; L146-S148 PolarHBondContact O-N 3.05Å; S148-G151 PolarHBondContact O-N 3.35Å; S148-V152 WeakPolarHBondContact O-CG2 3.33Å; S148-V152 PolarHBondContact O-N 2.93Å; S148-Y424 VanDerWaalsContact C-OH 3.26Å; S148-Y424 WeakPolarHBondContact CA-OH 3.2Å; S148-Y424 WeakPolarHBondContact CB-OH 3.32Å; S148-Y424 PolarHBondContact O-OH 3.47Å
149	R	89.8	Confident	85.7	Confident	11 Å²	11	32 Å²	32	4%	0.042	18%	0.179	C	C	.	.	H	α-helix	trans	-65.1	-44.7	175.6	-68.5	167.2	180	-89.5	-0.3	111.7	F124 W125 D129 Q145 L146 G151 V152 I153	F124-R149 HydrophobicContact CE1-CB 3.87Å; F124-R149 HydrophobicContact CE1-CG 4.44Å; F124-R149 HydrophobicContact CE2-CB 4.17Å; F124-R149 HydrophobicContact CZ-CB 3.55Å; F124-R149 PolarHBondContact O-NH1 3.34Å; W125-R149 VanDerWaalsContact O-CZ 3.26Å; W125-R149 PolarHBondContact O-NH1 3.46Å; W125-R149 PolarHBondContact O-NH2 3.36Å; W125-R149 VanDerWaalsContact O-NH2 3.09Å; D129-R149 IonicContact OD1-NH2 3.26Å; D129-R149 PolarHBondContact OD1-NH2 2.86Å; Q145-R149 VanDerWaalsContact O-CD 3.3Å; Q145-R149 WeakPolarHBondContact O-CD 3.48Å; Q145-R149 VanDerWaalsContact O-CG 3.29Å; Q145-R149 WeakPolarHBondContact O-CG 3.32Å; Q145-R149 PolarHBondContact O-N 3.39Å; L146-R149 PolarHBondContact O-N 3.02Å; R149-G151 VanDerWaalsContact C-N 3.26Å; R149-G151 PolarHBondContact O-N 2.81Å; R149-V152 PolarHBondContact O-N 2.75Å; R149-I153 PolarHBondContact O-N 3.25Å
150	V	91.9	Very high	87	Confident	0 Å²	0	33.1 Å²	33.1	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-57.7	-43.3	172.9	164.1	0	0	0	0	110.9	L83 L86 V87 F124 L146 I147 V152 I153 G154 M391 V394	L83-V150 HydrophobicContact CD2-CB 4.26Å; L83-V150 HydrophobicContact CD2-CG1 4.47Å; L83-V150 HydrophobicContact CD2-CG2 3.94Å; L86-V150 HydrophobicContact CD1-CG1 4.32Å; V87-V150 HydrophobicContact CG2-CG2 4.02Å; F124-V150 HydrophobicContact CE2-CG2 4.16Å; F124-V150 HydrophobicContact CZ-CG2 3.97Å; L146-V150 WeakPolarHBondContact O-CB 3.37Å; L146-V150 WeakPolarHBondContact O-CG2 3.49Å; L146-V150 PolarHBondContact O-N 3.35Å; I147-V150 PolarHBondContact O-N 3.08Å; V150-V152 PolarHBondContact O-N 3.15Å; V150-I153 PolarHBondContact O-N 3.03Å; V150-G154 PolarHBondContact O-N 2.93Å; V150-M391 HydrophobicContact CB-CE 3.97Å; V150-M391 HydrophobicContact CB-SD 4.06Å; V150-M391 HydrophobicContact CG1-CE 3.89Å; V150-M391 HydrophobicContact CG1-SD 3.53Å; V150-M391 VanDerWaalsContact CG1-SD 3.53Å; V150-M391 HydrophobicContact CG2-CE 3.95Å; V150-M391 HydrophobicContact CG2-SD 3.8Å; V150-V394 HydrophobicContact CG1-CB 3.9Å; V150-V394 HydrophobicContact CG1-CG1 3.69Å; V150-V394 HydrophobicContact CG1-CG2 4.23Å
151	G	90.7	Very high	88	Confident	0 Å²	0	30.5 Å²	30.5	0%	0	16%	0.159	C	C	.	.	H	α-helix	trans	-59.5	-43.3	176.7	0	0	0	0	0	112.8	I147 S148 R149 I153 G154 V155 S395	I147-G151 WeakPolarHBondContact O-CA 3.3Å; I147-G151 PolarHBondContact O-N 3.03Å; S148-G151 PolarHBondContact O-N 3.35Å; R149-G151 VanDerWaalsContact C-N 3.26Å; R149-G151 PolarHBondContact O-N 2.81Å; G151-I153 PolarHBondContact O-N 3.22Å; G151-G154 PolarHBondContact O-N 3.38Å; G151-V155 WeakPolarHBondContact O-CB 3.39Å; G151-V155 WeakPolarHBondContact O-CG2 3.28Å; G151-V155 PolarHBondContact O-N 3.17Å; G151-S395 WeakPolarHBondContact CA-OG 3.33Å; G151-S395 PolarHBondContact O-OG 3.35Å
152	V	91.2	Very high	88.9	Confident	3 Å²	3	25.7 Å²	25.7	2%	0.018	14%	0.137	C	C	.	.	H	α-helix	trans	-61.9	-47.5	178.6	176.7	0	0	0	0	110.7	L127 F131 I133 S148 R149 V150 T156 F423 Y424	L127-V152 HydrophobicContact CD2-CG1 4.39Å; F131-V152 HydrophobicContact CD2-CG1 4.22Å; F131-V152 HydrophobicContact CD2-CG2 4.22Å; F131-V152 HydrophobicContact CE1-CG1 4.37Å; F131-V152 HydrophobicContact CE2-CB 4.5Å; F131-V152 HydrophobicContact CE2-CG1 3.64Å; F131-V152 HydrophobicContact CE2-CG2 4.45Å; F131-V152 HydrophobicContact CG-CG2 4.49Å; F131-V152 HydrophobicContact CZ-CG1 3.71Å; I133-V152 HydrophobicContact CD1-CG2 3.79Å; S148-V152 WeakPolarHBondContact O-CG2 3.33Å; S148-V152 PolarHBondContact O-N 2.93Å; R149-V152 PolarHBondContact O-N 2.75Å; V150-V152 PolarHBondContact O-N 3.15Å; V152-T156 WeakPolarHBondContact O-CB 3.3Å; V152-T156 PolarHBondContact O-N 3.21Å; V152-T156 PolarHBondContact O-OG1 3.08Å; V152-F423 HydrophobicContact CG2-CE1 3.92Å; V152-Y424 HydrophobicContact CG2-CE1 3.85Å
153	I	92.4	Very high	89.3	Confident	45 Å²	45	24.6 Å²	24.6	23%	0.231	13%	0.129	C	C	.	.	H	α-helix	trans	-64.6	-46.3	-178.5	-61.7	172.9	0	0	0	110.2	F124 L127 R149 V150 G151 T156 L157 M391	F124-I153 HydrophobicContact CD2-CD1 4.04Å; F124-I153 HydrophobicContact CE2-CD1 4.05Å; L127-I153 HydrophobicContact CD1-CD1 4.24Å; L127-I153 HydrophobicContact CD1-CG1 4.19Å; L127-I153 HydrophobicContact CD2-CD1 4.29Å; L127-I153 HydrophobicContact CD2-CG1 3.94Å; R149-I153 PolarHBondContact O-N 3.25Å; V150-I153 PolarHBondContact O-N 3.03Å; G151-I153 PolarHBondContact O-N 3.22Å; I153-T156 WeakPolarHBondContact O-CB 3.24Å; I153-T156 PolarHBondContact O-N 2.97Å; I153-L157 HydrophobicContact CG2-CD1 4.26Å; I153-L157 WeakPolarHBondContact O-CG 3.4Å; I153-L157 PolarHBondContact O-N 3.09Å; I153-M391 HydrophobicContact CB-CE 3.5Å; I153-M391 HydrophobicContact CD1-CE 3.74Å; I153-M391 HydrophobicContact CG1-CE 4.15Å; I153-M391 HydrophobicContact CG2-CE 3.67Å
154	G	93	Very high	89.6	Confident	0 Å²	0	26.5 Å²	26.5	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-72.2	-34.2	-179.1	0	0	0	0	0	114	V150 G151 T156 L157 M158 S395	V150-G154 PolarHBondContact O-N 2.93Å; G151-G154 PolarHBondContact O-N 3.38Å; G154-T156 VanDerWaalsContact C-N 3.31Å; G154-L157 PolarHBondContact O-N 3.43Å; G154-M158 WeakPolarHBondContact O-CB 3.33Å; G154-M158 PolarHBondContact O-N 2.85Å; G154-S395 VanDerWaalsContact C-CB 3.43Å; G154-S395 WeakPolarHBondContact CA-OG 3.34Å
155	V	91.9	Very high	89.8	Confident	0 Å²	0	25.3 Å²	25.3	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-63.3	-40.5	170.7	170.5	0	0	0	0	110.3	G151 M158 A159 S395 L399 Y424 F428	G151-V155 WeakPolarHBondContact O-CB 3.39Å; G151-V155 WeakPolarHBondContact O-CG2 3.28Å; G151-V155 PolarHBondContact O-N 3.17Å; V155-M158 PolarHBondContact O-N 3.49Å; V155-A159 WeakPolarHBondContact O-CB 3.23Å; V155-A159 PolarHBondContact O-N 3.38Å; V155-S395 PolarHBondContact N-OG 3.45Å; V155-S395 VanDerWaalsContact N-OG 3.12Å; V155-L399 HydrophobicContact CG2-CD1 4.16Å; V155-L399 HydrophobicContact CG2-CD2 4.39Å; V155-L399 HydrophobicContact CG2-CG 4.26Å; V155-Y424 HydrophobicContact CG2-CD1 4.01Å; V155-F428 HydrophobicContact CG1-CB 3.69Å; V155-F428 HydrophobicContact CG1-CD2 4.14Å; V155-F428 HydrophobicContact CG1-CG 4.43Å
156	T	93	Very high	90	Very high	33 Å²	33	24.7 Å²	24.7	20%	0.202	13%	0.134	C	C	.	.	H	α-helix	trans	-58.7	-49.2	173.9	-53.8	0	0	0	0	110.6	V152 I153 G154 M158 A159 L160 W427 I431	V152-T156 WeakPolarHBondContact O-CB 3.3Å; V152-T156 PolarHBondContact O-N 3.21Å; V152-T156 PolarHBondContact O-OG1 3.08Å; I153-T156 WeakPolarHBondContact O-CB 3.24Å; I153-T156 PolarHBondContact O-N 2.97Å; G154-T156 VanDerWaalsContact C-N 3.31Å; T156-M158 PolarHBondContact O-N 2.86Å; T156-A159 PolarHBondContact O-N 2.84Å; T156-L160 HydrophobicContact CG2-CD1 4.17Å; T156-L160 HydrophobicContact CG2-CG 4.44Å; T156-L160 WeakPolarHBondContact O-CB 3.45Å; T156-L160 VanDerWaalsContact O-CG 3.24Å; T156-L160 WeakPolarHBondContact O-CG 3.28Å; T156-L160 PolarHBondContact O-N 3.23Å; T156-W427 PolarHBondContact OG1-NE1 3.4Å; T156-I431 HydrophobicContact CG2-CG1 4.45Å; T156-I431 HydrophobicContact CG2-CG2 4.07Å
157	L	90.6	Very high	90.1	Very high	46 Å²	46	24.5 Å²	24.5	24%	0.241	13%	0.134	C	C	.	.	H	α-helix	trans	-60.1	-45.4	177.6	-70.4	167.2	0	0	0	112.2	I153 G154 L160 L161 I388	I153-L157 HydrophobicContact CG2-CD1 4.26Å; I153-L157 WeakPolarHBondContact O-CG 3.4Å; I153-L157 PolarHBondContact O-N 3.09Å; G154-L157 PolarHBondContact O-N 3.43Å; L157-L160 PolarHBondContact O-N 3.42Å; L157-L161 WeakPolarHBondContact O-CG 3.29Å; L157-L161 PolarHBondContact O-N 2.94Å; L157-I388 HydrophobicContact CD1-CB 4.49Å; L157-I388 HydrophobicContact CD1-CG1 4.32Å; L157-I388 HydrophobicContact CD1-CG2 4.23Å
158	M	89.4	Confident	90.1	Very high	43 Å²	43	26.6 Å²	26.6	21%	0.212	15%	0.145	C	C	.	.	H	α-helix	trans	-63.6	-41.7	178.7	-172.6	-177.5	175.1	0	0	111.8	G154 V155 T156 S162 Y392 L399 F428	G154-M158 WeakPolarHBondContact O-CB 3.33Å; G154-M158 PolarHBondContact O-N 2.85Å; V155-M158 PolarHBondContact O-N 3.49Å; T156-M158 PolarHBondContact O-N 2.86Å; M158-S162 VanDerWaalsContact O-CB 3.27Å; M158-S162 WeakPolarHBondContact O-CB 3.28Å; M158-S162 PolarHBondContact O-N 3.34Å; M158-Y392 HydrophobicContact CB-CD2 3.95Å; M158-Y392 HydrophobicContact CB-CE2 3.85Å; M158-Y392 HydrophobicContact CG-CD2 4.22Å; M158-Y392 HydrophobicContact CG-CE2 3.62Å; M158-Y392 HydrophobicContact SD-CE2 4.49Å; M158-L399 HydrophobicContact CE-CD1 4.32Å; M158-L399 HydrophobicContact SD-CD1 3.63Å; M158-F428 HydrophobicContact CB-CE2 4.42Å; M158-F428 HydrophobicContact CG-CE2 4Å; M158-F428 HydrophobicContact SD-CE2 4.32Å
159	A	91.8	Very high	89.9	Confident	0 Å²	0	28.8 Å²	28.8	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-67.7	-42.2	178.7	0	0	0	0	0	112	V155 T156 S162 G163 F428 I431 F432	V155-A159 WeakPolarHBondContact O-CB 3.23Å; V155-A159 PolarHBondContact O-N 3.38Å; T156-A159 PolarHBondContact O-N 2.84Å; A159-S162 PolarHBondContact O-N 3.03Å; A159-G163 PolarHBondContact O-N 3.45Å; A159-F428 HydrophobicContact CB-CD2 3.66Å; A159-F428 HydrophobicContact CB-CE2 3.87Å; A159-F428 HydrophobicContact CB-CG 4.2Å; A159-F428 WeakPolarHBondContact CB-O 3.23Å; A159-I431 HydrophobicContact CB-CB 3.7Å; A159-I431 HydrophobicContact CB-CG2 3.63Å; A159-F432 HydrophobicContact CB-CB 4.31Å
160	L	91.5	Very high	89.7	Confident	75 Å²	75	28.7 Å²	28.7	39%	0.393	16%	0.161	S	C	.	.	H	α-helix	trans	-61.2	-48.4	174.5	-70.9	175.5	0	0	0	111.6	T156 L157 S162 G163 F164 I431 S435	T156-L160 HydrophobicContact CG2-CD1 4.17Å; T156-L160 HydrophobicContact CG2-CG 4.44Å; T156-L160 WeakPolarHBondContact O-CB 3.45Å; T156-L160 VanDerWaalsContact O-CG 3.24Å; T156-L160 WeakPolarHBondContact O-CG 3.28Å; T156-L160 PolarHBondContact O-N 3.23Å; L157-L160 PolarHBondContact O-N 3.42Å; L160-S162 VanDerWaalsContact C-N 3.34Å; L160-S162 PolarHBondContact O-N 3.5Å; L160-G163 PolarHBondContact O-N 2.94Å; L160-F164 WeakPolarHBondContact O-CB 3.28Å; L160-F164 PolarHBondContact O-N 3.45Å; L160-I431 HydrophobicContact CD2-CG2 3.74Å; L160-I431 HydrophobicContact CG-CG2 3.8Å; L160-S435 PolarHBondContact O-OG 3Å
161	L	87.8	Confident	89.3	Confident	75 Å²	75	32.1 Å²	32.1	39%	0.393	17%	0.174	S	C	.	.	H	α-helix	trans	-65	-39.6	178.3	-69.5	174.6	0	0	0	111.7	L157 G165	L157-L161 WeakPolarHBondContact O-CG 3.29Å; L157-L161 PolarHBondContact O-N 2.94Å; L161-G165 PolarHBondContact O-N 2.79Å
162	S	88.9	Confident	89	Confident	35 Å²	35	34.8 Å²	34.8	25%	0.245	19%	0.191	C	C	.	.	H	α-helix	trans	-69.2	-37.5	177	-176.2	0	0	0	0	112.3	M158 A159 L160 A166 K302 F432	M158-S162 VanDerWaalsContact O-CB 3.27Å; M158-S162 WeakPolarHBondContact O-CB 3.28Å; M158-S162 PolarHBondContact O-N 3.34Å; A159-S162 PolarHBondContact O-N 3.03Å; L160-S162 VanDerWaalsContact C-N 3.34Å; L160-S162 PolarHBondContact O-N 3.5Å; S162-A166 WeakPolarHBondContact O-CB 3.24Å; S162-A166 PolarHBondContact O-N 3.18Å; S162-K302 PolarHBondContact OG-NZ 3.07Å; S162-K302 VanDerWaalsContact OG-NZ 3.11Å; S162-F432 WeakPolarHBondContact O-CE2 3.2Å
163	G	90.1	Very high	88.5	Confident	0 Å²	0	39.2 Å²	39.2	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-68.8	-48.3	179.3	0	0	0	0	0	111.4	A159 L160 G165 A166	A159-G163 PolarHBondContact O-N 3.45Å; L160-G163 PolarHBondContact O-N 2.94Å; G163-G165 PolarHBondContact O-N 3.49Å; G163-A166 PolarHBondContact O-N 2.98Å
164	F	89.6	Confident	88	Confident	99 Å²	99	37.6 Å²	37.6	43%	0.434	20%	0.199	S	C	.	.	H	α-helix	trans	-57.5	-47.2	170.9	175.9	-100.2	0	0	0	111.8	L160 A166 V167 N168 S435	L160-F164 WeakPolarHBondContact O-CB 3.28Å; L160-F164 PolarHBondContact O-N 3.45Å; F164-A166 VanDerWaalsContact C-N 3.31Å; F164-A166 PolarHBondContact O-N 2.82Å; F164-V167 PolarHBondContact O-N 3.41Å; F164-N168 HydrophobicContact CD1-CB 4.2Å; F164-N168 HydrophobicContact CE1-CB 3.77Å; F164-N168 HydrophobicContact CE2-CB 4.11Å; F164-N168 HydrophobicContact CZ-CB 3.72Å; F164-N168 VanDerWaalsContact O-CB 3.28Å; F164-N168 WeakPolarHBondContact O-CB 3.43Å; F164-N168 PolarHBondContact O-N 2.96Å; F164-S435 PolarHBondContact N-OG 3.06Å
165	G	86.9	Confident	87.4	Confident	20 Å²	20	39.8 Å²	39.8	21%	0.206	22%	0.215	C	C	.	.	H	α-helix	trans	-62	-34.9	178.8	0	0	0	0	0	113.5	L161 G163 V167 C169	L161-G165 PolarHBondContact O-N 2.79Å; G163-G165 PolarHBondContact O-N 3.49Å; G165-V167 PolarHBondContact O-N 3.3Å; G165-C169 WeakPolarHBondContact O-CB 3.48Å; G165-C169 PolarHBondContact O-N 3.45Å; G165-C169 PolarHBondContact O-SG 2.94Å
166	A	87.4	Confident	86.9	Confident	8 Å²	8	48 Å²	48	7%	0.066	25%	0.247	C	C	.	.	H	α-helix	trans	-63.4	-24.3	178.5	0	0	0	0	0	113.1	S162 G163 F164 P170 C299 F432	S162-A166 WeakPolarHBondContact O-CB 3.24Å; S162-A166 PolarHBondContact O-N 3.18Å; G163-A166 PolarHBondContact O-N 2.98Å; F164-A166 VanDerWaalsContact C-N 3.31Å; F164-A166 PolarHBondContact O-N 2.82Å; A166-P170 VanDerWaalsContact O-CD 3.3Å; A166-P170 WeakPolarHBondContact O-CD 3.26Å; A166-P170 WeakPolarHBondContact O-CG 3.46Å; A166-C299 VanDerWaalsContact CA-SG 3.52Å; A166-C299 HydrophobicContact CB-CB 4.13Å; A166-C299 VanDerWaalsContact O-CB 3.3Å; A166-C299 WeakPolarHBondContact O-CB 3.43Å; A166-C299 PolarHBondContact O-SG 2.94Å; A166-F432 HydrophobicContact CB-CE2 3.97Å; A166-F432 HydrophobicContact CB-CZ 3.97Å
167	V	89.6	Confident	86.3	Confident	19 Å²	19	50.3 Å²	50.3	12%	0.115	25%	0.254	C	S	.	.	H	α-helix	trans	-102.3	-45.9	-178.8	-178.3	0	0	0	0	110.7	F164 G165 C169 P170 Y171 A436 I440 L443	F164-V167 PolarHBondContact O-N 3.41Å; G165-V167 PolarHBondContact O-N 3.3Å; V167-C169 PolarHBondContact O-N 3.41Å; V167-P170 WeakPolarHBondContact O-CD 3.44Å; V167-Y171 WeakPolarHBondContact O-CB 3.32Å; V167-Y171 PolarHBondContact O-N 3.43Å; V167-A436 HydrophobicContact CG2-CB 4.12Å; V167-A436 WeakPolarHBondContact CG2-O 3.37Å; V167-I440 HydrophobicContact CB-CG1 4.39Å; V167-I440 HydrophobicContact CG1-CG1 3.72Å; V167-I440 HydrophobicContact CG2-CD1 4.18Å; V167-I440 HydrophobicContact CG2-CG1 3.71Å; V167-L443 HydrophobicContact CG1-CD1 3.66Å
168	N	87.6	Confident	85.8	Confident	47 Å²	47	49.8 Å²	49.8	25%	0.251	25%	0.252	S	S	.	.	H	α-helix	trans	-70.1	-30.9	-176.4	-171.9	62.1	0	0	0	113.1	F164 T172	F164-N168 HydrophobicContact CD1-CB 4.2Å; F164-N168 HydrophobicContact CE1-CB 3.77Å; F164-N168 HydrophobicContact CE2-CB 4.11Å; F164-N168 HydrophobicContact CZ-CB 3.72Å; F164-N168 VanDerWaalsContact O-CB 3.28Å; F164-N168 WeakPolarHBondContact O-CB 3.43Å; F164-N168 PolarHBondContact O-N 2.96Å; N168-T172 VanDerWaalsContact O-CB 3.29Å; N168-T172 WeakPolarHBondContact O-CB 3.36Å; N168-T172 PolarHBondContact O-N 3.37Å; N168-T172 PolarHBondContact O-OG1 3.34Å
169	C	83	Confident	85.2	Confident	46 Å²	46	51.6 Å²	51.6	31%	0.311	26%	0.256	S	S	.	.	H	α-helix	trans	-66.4	-53.4	178.9	-72.3	0	0	0	0	112.4	G165 V167 Y171 T172 Y173	G165-C169 WeakPolarHBondContact O-CB 3.48Å; G165-C169 PolarHBondContact O-N 3.45Å; G165-C169 PolarHBondContact O-SG 2.94Å; V167-C169 PolarHBondContact O-N 3.41Å; C169-Y171 VanDerWaalsContact C-N 3.3Å; C169-Y171 PolarHBondContact O-N 2.92Å; C169-T172 PolarHBondContact O-N 3.46Å; C169-Y173 PolarHBondContact O-N 3.12Å
170	P	85.3	Confident	84.6	Confident	9 Å²	9	58.5 Å²	58.5	6%	0.058	29%	0.293	C	S	.	.	H	α-helix	trans	-55.8	-44.3	172	-26.2	34.6	0	0	0	112.5	A166 V167 T172 Y173 M174	A166-P170 VanDerWaalsContact O-CD 3.3Å; A166-P170 WeakPolarHBondContact O-CD 3.26Å; A166-P170 WeakPolarHBondContact O-CG 3.46Å; V167-P170 WeakPolarHBondContact O-CD 3.44Å; P170-T172 VanDerWaalsContact C-N 3.31Å; P170-T172 PolarHBondContact O-N 2.95Å; P170-Y173 PolarHBondContact O-N 3.26Å; P170-M174 HydrophobicContact CB-SD 4.01Å; P170-M174 VanDerWaalsContact O-CB 3.24Å; P170-M174 WeakPolarHBondContact O-CB 3.39Å; P170-M174 VanDerWaalsContact O-CG 3.26Å; P170-M174 WeakPolarHBondContact O-CG 3.3Å; P170-M174 PolarHBondContact O-N 3.18Å
171	Y	84.8	Confident	84.2	Confident	71 Å²	71	55.9 Å²	55.9	28%	0.278	28%	0.28	S	S	.	.	H	α-helix	trans	-59.2	-39.6	178.8	-178.1	-104.8	0	0	0	113.1	V167 C169 F177 L443	V167-Y171 WeakPolarHBondContact O-CB 3.32Å; V167-Y171 PolarHBondContact O-N 3.43Å; C169-Y171 VanDerWaalsContact C-N 3.3Å; C169-Y171 PolarHBondContact O-N 2.92Å; Y171-F177 HydrophobicContact CD2-CB 3.86Å; Y171-F177 HydrophobicContact CD2-CD1 4.28Å; Y171-F177 HydrophobicContact CD2-CD2 4.36Å; Y171-F177 AromaticContact CD2-CG 3.93Å; Y171-F177 HydrophobicContact CD2-CG 3.93Å; Y171-F177 HydrophobicContact CE2-CB 4.06Å; Y171-F177 HydrophobicContact CE2-CG 4.43Å; Y171-L443 HydrophobicContact CD1-CD1 4.11Å; Y171-L443 HydrophobicContact CD1-CD2 3.97Å; Y171-L443 HydrophobicContact CD2-CD1 3.96Å; Y171-L443 HydrophobicContact CE1-CD2 3.84Å; Y171-L443 HydrophobicContact CE2-CD2 4.44Å; Y171-L443 HydrophobicContact CG-CD1 3.71Å; Y171-L443 HydrophobicContact CG-CD2 4.33Å
172	T	82.6	Confident	84.2	Confident	57 Å²	57	55.5 Å²	55.5	35%	0.35	28%	0.281	S	S	.	.	H	α-helix	trans	-79.7	-36.2	-177.7	-56.7	0	0	0	0	112.9	N168 C169 P170	N168-T172 VanDerWaalsContact O-CB 3.29Å; N168-T172 WeakPolarHBondContact O-CB 3.36Å; N168-T172 PolarHBondContact O-N 3.37Å; N168-T172 PolarHBondContact O-OG1 3.34Å; C169-T172 PolarHBondContact O-N 3.46Å; P170-T172 VanDerWaalsContact C-N 3.31Å; P170-T172 PolarHBondContact O-N 2.95Å
173	Y	80.9	Confident	84.2	Confident	96 Å²	96	58.2 Å²	58.2	38%	0.376	29%	0.292	S	S	.	.	H	α-helix	trans	-92.6	-26.3	-173	-67	-31.2	0	0	0	114.5	C169 P170 F288 N289	C169-Y173 PolarHBondContact O-N 3.12Å; P170-Y173 PolarHBondContact O-N 3.26Å; Y173-F288 HydrophobicContact CD1-CB 4.49Å; Y173-F288 HydrophobicContact CD1-CD1 4.38Å; Y173-F288 HydrophobicContact CE1-CD1 4.18Å; Y173-F288 HydrophobicContact CE2-CD1 4.49Å; Y173-N289 WeakPolarHBondContact O-CA 3.5Å
174	M	82.8	Confident	84.2	Confident	11 Å²	11	62.7 Å²	62.7	5%	0.054	32%	0.32	C	S	.	.			trans	-79	127.1	-177.8	-69.2	175.6	58.5	0	0	111.5	P170 Y176 F177 L178 N289 Y293	P170-M174 HydrophobicContact CB-SD 4.01Å; P170-M174 VanDerWaalsContact O-CB 3.24Å; P170-M174 WeakPolarHBondContact O-CB 3.39Å; P170-M174 VanDerWaalsContact O-CG 3.26Å; P170-M174 WeakPolarHBondContact O-CG 3.3Å; P170-M174 PolarHBondContact O-N 3.18Å; M174-Y176 PolarHBondContact O-N 3.46Å; M174-F177 HydrophobicContact CB-CD2 3.96Å; M174-F177 HydrophobicContact CB-CE2 4.45Å; M174-F177 HydrophobicContact CE-CD2 4.5Å; M174-F177 HydrophobicContact CE-CE2 4.03Å; M174-F177 PolarHBondContact O-N 2.9Å; M174-F177 HydrophobicContact SD-CD2 4.33Å; M174-F177 HydrophobicContact SD-CE2 3.88Å; M174-L178 WeakPolarHBondContact O-CD1 3.45Å; M174-N289 WeakPolarHBondContact CA-OD1 3.45Å; M174-Y293 HydrophobicContact CE-CD1 3.77Å; M174-Y293 HydrophobicContact CE-CE1 3.48Å; M174-Y293 VanDerWaalsContact CE-CE1 3.48Å
175	S	79.9	Confident	84.1	Confident	46 Å²	46	59.7 Å²	59.7	32%	0.322	31%	0.308	S	S	.	.	G	3₁₀ helix	trans	-60.8	-24.6	173	64	0	0	0	0	113.1	F177 L178 N289	S175-F177 VanDerWaalsContact C-N 3.29Å; S175-F177 PolarHBondContact O-N 3.21Å; S175-L178 PolarHBondContact O-N 3.27Å; S175-N289 PolarHBondContact N-OD1 2.98Å; S175-N289 PolarHBondContact OG-ND2 2.76Å; S175-N289 PolarHBondContact OG-OD1 3.17Å
176	Y	81.2	Confident	84.3	Confident	171 Å²	171	58.9 Å²	58.9	67%	0.671	30%	0.3	S	S	*	.	G	3₁₀ helix	trans	-59.3	-35.4	177.8	-178.6	-96	0	0	0	113.4	M174	M174-Y176 PolarHBondContact O-N 3.46Å
177	F	81.6	Confident	84.5	Confident	82 Å²	82	62.5 Å²	62.5	36%	0.36	32%	0.317	S	S	.	.	G	3₁₀ helix	trans	-90.1	2.4	-179.6	-64.9	-65.9	0	0	0	113.4	Y171 M174 S175 R179	Y171-F177 HydrophobicContact CD2-CB 3.86Å; Y171-F177 HydrophobicContact CD2-CD1 4.28Å; Y171-F177 HydrophobicContact CD2-CD2 4.36Å; Y171-F177 AromaticContact CD2-CG 3.93Å; Y171-F177 HydrophobicContact CD2-CG 3.93Å; Y171-F177 HydrophobicContact CE2-CB 4.06Å; Y171-F177 HydrophobicContact CE2-CG 4.43Å; M174-F177 HydrophobicContact CB-CD2 3.96Å; M174-F177 HydrophobicContact CB-CE2 4.45Å; M174-F177 HydrophobicContact CE-CD2 4.5Å; M174-F177 HydrophobicContact CE-CE2 4.03Å; M174-F177 PolarHBondContact O-N 2.9Å; M174-F177 HydrophobicContact SD-CD2 4.33Å; M174-F177 HydrophobicContact SD-CE2 3.88Å; S175-F177 VanDerWaalsContact C-N 3.29Å; S175-F177 PolarHBondContact O-N 3.21Å; F177-R179 PolarHBondContact O-N 2.97Å
178	L	78.9	Confident	84.6	Confident	36 Å²	36	64.3 Å²	64.3	19%	0.188	33%	0.334	C	S	.	.	S	Bend	trans	-75.4	126.5	173.7	-85.8	95.1	0	0	0	110.4	M174 S175 N180 R276 I277	M174-L178 WeakPolarHBondContact O-CD1 3.45Å; S175-L178 PolarHBondContact O-N 3.27Å; L178-N180 PolarHBondContact O-N 2.87Å; L178-R276 HydrophobicContact CD2-CB 3.69Å; L178-I277 HydrophobicContact CD2-CB 4.44Å; L178-I277 HydrophobicContact CD2-CG1 3.67Å
179	R	78.3	Confident	84.8	Confident	81 Å²	81	62.9 Å²	62.9	31%	0.306	33%	0.327	S	S	.	.			trans	-61.9	131.6	167.3	-179.1	178.2	-178.3	-178.6	4.4	109.2	F177 V181 T273 P451	F177-R179 PolarHBondContact O-N 2.97Å; R179-V181 HydrophobicContact CG-CG2 4.24Å; R179-V181 PolarHBondContact O-N 3.4Å; R179-T273 HydrophobicContact CB-CG2 4.43Å; R179-P451 PolarHBondContact NH2-O 2.95Å
180	N	78.4	Confident	85.3	Confident	144 Å²	144	63.3 Å²	63.3	77%	0.77	32%	0.324	S	S	*	.			trans	-71.9	115.4	171.4	-69.6	-40.2	0	0	0	109.2	L178	L178-N180 PolarHBondContact O-N 2.87Å
181	V	82.9	Confident	85.8	Confident	20 Å²	20	70.9 Å²	70.9	12%	0.121	35%	0.351	C	S	.	.			trans	-116.5	127.6	176.9	179.9	0	0	0	0	108.3	R179 I186 L270 T273 I277	R179-V181 HydrophobicContact CG-CG2 4.24Å; R179-V181 PolarHBondContact O-N 3.4Å; V181-I186 HydrophobicContact CG1-CD1 3.96Å; V181-I186 HydrophobicContact CG1-CG1 3.87Å; V181-L270 HydrophobicContact CG1-CB 4.27Å; V181-L270 HydrophobicContact CG1-CD2 3.93Å; V181-L270 HydrophobicContact CG2-CD2 3.71Å; V181-T273 HydrophobicContact CG2-CG2 3.62Å; V181-I277 HydrophobicContact CB-CD1 4.27Å
182	T	86.8	Confident	86.2	Confident	67 Å²	67	73.9 Å²	73.9	41%	0.411	36%	0.362	S	S	.	.			trans	-102.4	154.8	175.7	59.8	0	0	0	0	110.8	T184 D185 I186	T182-T184 PolarHBondContact O-N 2.66Å; T182-T184 PolarHBondContact OG1-OG1 2.92Å; T182-D185 WeakPolarHBondContact O-CB 3.42Å; T182-D185 PolarHBondContact O-N 3.37Å; T182-D185 PolarHBondContact OG1-OD1 3.35Å; T182-D185 PolarHBondContact OG1-OD2 2.89Å; T182-I186 PolarHBondContact O-N 2.93Å
183	D	89.8	Confident	86.7	Confident	92 Å²	92	72 Å²	72	49%	0.492	35%	0.35	S	S	.	.	H	α-helix	trans	-60.1	-31.2	177.5	-67.6	-43.3	0	0	0	112.5	D185 I186 L187 K274	D183-D185 PolarHBondContact O-N 2.87Å; D183-I186 PolarHBondContact O-N 3.42Å; D183-L187 VanDerWaalsContact O-CG 3.31Å; D183-L187 WeakPolarHBondContact O-CG 3.4Å; D183-L187 PolarHBondContact O-N 3.42Å; D183-K274 VanDerWaalsContact OD1-CE 3.25Å; D183-K274 WeakPolarHBondContact OD1-CE 3.39Å; D183-K274 IonicContact OD1-NZ 2.56Å; D183-K274 PolarHBondContact OD1-NZ 3.39Å
184	T	89.5	Confident	87.4	Confident	95 Å²	95	72.4 Å²	72.4	58%	0.583	36%	0.358	S	S	*	.	H	α-helix	trans	-63.7	-31.9	175.5	48	0	0	0	0	112.5	T182 A188	T182-T184 PolarHBondContact O-N 2.66Å; T182-T184 PolarHBondContact OG1-OG1 2.92Å; T184-A188 VanDerWaalsContact O-CB 3.3Å; T184-A188 WeakPolarHBondContact O-CB 3.35Å; T184-A188 PolarHBondContact O-N 3.21Å
185	D	87.9	Confident	88	Confident	35 Å²	35	77.8 Å²	77.8	19%	0.187	38%	0.383	C	S	.	.	H	α-helix	trans	-74.7	-41.3	-178.5	-62.8	-20.1	0	0	0	111.6	T182 D183 A188 L189 K453	T182-D185 WeakPolarHBondContact O-CB 3.42Å; T182-D185 PolarHBondContact O-N 3.37Å; T182-D185 PolarHBondContact OG1-OD1 3.35Å; T182-D185 PolarHBondContact OG1-OD2 2.89Å; D183-D185 PolarHBondContact O-N 2.87Å; D185-A188 PolarHBondContact O-N 3.23Å; D185-L189 PolarHBondContact O-N 3.45Å; D185-K453 IonicContact OD1-NZ 2.75Å; D185-K453 PolarHBondContact OD1-NZ 2.88Å; D185-K453 IonicContact OD2-NZ 3.9Å; D185-K453 PolarHBondContact OD2-NZ 3.24Å
186	I	90.3	Very high	88.7	Confident	4 Å²	4	75.8 Å²	75.8	2%	0.021	37%	0.369	C	S	.	.	H	α-helix	trans	-60.9	-50.2	173.7	-65.2	168.7	0	0	0	109.3	V181 T182 D183 A188 L189 E190 L270 Y271 K274	V181-I186 HydrophobicContact CG1-CD1 3.96Å; V181-I186 HydrophobicContact CG1-CG1 3.87Å; T182-I186 PolarHBondContact O-N 2.93Å; D183-I186 PolarHBondContact O-N 3.42Å; I186-A188 VanDerWaalsContact C-N 3.32Å; I186-A188 PolarHBondContact O-N 3.46Å; I186-L189 PolarHBondContact O-N 3.35Å; I186-E190 HydrophobicContact CG2-CG 4.39Å; I186-E190 WeakPolarHBondContact O-CB 3.43Å; I186-E190 WeakPolarHBondContact O-CG 3.47Å; I186-E190 PolarHBondContact O-N 2.96Å; I186-L270 HydrophobicContact CG1-CB 3.97Å; I186-L270 HydrophobicContact CG1-CD1 4.36Å; I186-Y271 HydrophobicContact CG2-CD2 4.21Å; I186-Y271 HydrophobicContact CG2-CE1 3.99Å; I186-Y271 HydrophobicContact CG2-CE2 3.54Å; I186-Y271 VanDerWaalsContact CG2-CZ 3.42Å; I186-K274 HydrophobicContact CD1-CB 4.13Å; I186-K274 HydrophobicContact CD1-CD 3.64Å; I186-K274 HydrophobicContact CD1-CG 4.45Å
187	L	93.2	Very high	89.3	Confident	84 Å²	84	71.7 Å²	71.7	44%	0.44	36%	0.357	S	S	.	.	H	α-helix	trans	-62	-37.5	179.2	-71	172.5	0	0	0	112.8	D183 R191	D183-L187 VanDerWaalsContact O-CG 3.31Å; D183-L187 WeakPolarHBondContact O-CG 3.4Å; D183-L187 PolarHBondContact O-N 3.42Å; L187-R191 WeakPolarHBondContact O-CB 3.19Å; L187-R191 VanDerWaalsContact O-CG 3.24Å; L187-R191 WeakPolarHBondContact O-CG 3.38Å; L187-R191 PolarHBondContact O-N 3.01Å
188	A	91.9	Very high	90	Very high	57 Å²	57	72.8 Å²	72.8	47%	0.471	37%	0.367	S	S	.	.	H	α-helix	trans	-65	-42.5	176.9	0	0	0	0	0	111.6	T184 D185 I186 R191 R192	T184-A188 VanDerWaalsContact O-CB 3.3Å; T184-A188 WeakPolarHBondContact O-CB 3.35Å; T184-A188 PolarHBondContact O-N 3.21Å; D185-A188 PolarHBondContact O-N 3.23Å; I186-A188 VanDerWaalsContact C-N 3.32Å; I186-A188 PolarHBondContact O-N 3.46Å; A188-R191 PolarHBondContact O-N 2.87Å; A188-R192 PolarHBondContact O-N 2.97Å; A188-R192 VanDerWaalsContact O-N 3.11Å
189	L	91.2	Very high	90.7	Very high	17 Å²	17	75.4 Å²	75.4	9%	0.089	38%	0.379	C	S	.	.	H	α-helix	trans	-71.2	-39.7	179.1	-164.8	67.5	0	0	0	112.1	D185 I186 R191 R192 L193 L263 E266 T267 L270	D185-L189 PolarHBondContact O-N 3.45Å; I186-L189 PolarHBondContact O-N 3.35Å; L189-R191 VanDerWaalsContact C-N 3.35Å; L189-R191 PolarHBondContact O-N 3.47Å; L189-R192 WeakPolarHBondContact O-CB 3.36Å; L189-R192 PolarHBondContact O-N 2.93Å; L189-R192 VanDerWaalsContact O-N 3.16Å; L189-L193 PolarHBondContact O-N 3.33Å; L189-L263 HydrophobicContact CD1-CD2 3.64Å; L189-E266 HydrophobicContact CD2-CB 3.88Å; L189-E266 HydrophobicContact CD2-CG 3.6Å; L189-T267 WeakPolarHBondContact CD2-OG1 3.45Å; L189-L270 HydrophobicContact CB-CD1 4.44Å; L189-L270 HydrophobicContact CD2-CD1 3.69Å; L189-L270 HydrophobicContact CD2-CG 4.48Å
190	E	93.4	Very high	91.5	Very high	55 Å²	55	72.2 Å²	72.2	26%	0.257	37%	0.368	S	S	.	.	H	α-helix	trans	-58.8	-45.2	172.7	-77.7	-176	157	0	0	111.9	I186 R192 L193 L194 T267 Y271	I186-E190 HydrophobicContact CG2-CG 4.39Å; I186-E190 WeakPolarHBondContact O-CB 3.43Å; I186-E190 WeakPolarHBondContact O-CG 3.47Å; I186-E190 PolarHBondContact O-N 2.96Å; E190-R192 VanDerWaalsContact C-N 3.3Å; E190-R192 PolarHBondContact O-N 2.88Å; E190-L193 PolarHBondContact O-N 3.47Å; E190-L194 WeakPolarHBondContact O-CG 3.5Å; E190-L194 PolarHBondContact O-N 2.83Å; E190-T267 HydrophobicContact CG-CG2 3.87Å; E190-Y271 WeakPolarHBondContact OE1-CE2 3.33Å; E190-Y271 VanDerWaalsContact OE1-CZ 3.26Å; E190-Y271 PolarHBondContact OE1-OH 2.99Å
191	R	95.1	Very high	92.3	Very high	167 Å²	167	70.4 Å²	70.4	63%	0.63	36%	0.357	S	S	*	.	H	α-helix	trans	-59.7	-42.4	175.3	-75.1	173.6	-173.5	-177.9	3.1	111.4	L187 A188 L189 L194 Q195	L187-R191 WeakPolarHBondContact O-CB 3.19Å; L187-R191 VanDerWaalsContact O-CG 3.24Å; L187-R191 WeakPolarHBondContact O-CG 3.38Å; L187-R191 PolarHBondContact O-N 3.01Å; A188-R191 PolarHBondContact O-N 2.87Å; L189-R191 VanDerWaalsContact C-N 3.35Å; L189-R191 PolarHBondContact O-N 3.47Å; R191-L194 PolarHBondContact O-N 3.42Å; R191-Q195 WeakPolarHBondContact O-CB 3.34Å; R191-Q195 WeakPolarHBondContact O-CG 3.3Å; R191-Q195 PolarHBondContact O-N 3.41Å
192	R	93.4	Very high	92.9	Very high	134 Å²	134	72 Å²	72	51%	0.506	37%	0.369	S	S	.	.	H	α-helix	trans	-64.9	-39.9	177.1	-171.3	179.6	-179.3	-171.7	0.3	112.2	A188 L189 E190 T196 L263	A188-R192 PolarHBondContact O-N 2.97Å; A188-R192 VanDerWaalsContact O-N 3.11Å; L189-R192 WeakPolarHBondContact O-CB 3.36Å; L189-R192 PolarHBondContact O-N 2.93Å; L189-R192 VanDerWaalsContact O-N 3.16Å; E190-R192 VanDerWaalsContact C-N 3.3Å; E190-R192 PolarHBondContact O-N 2.88Å; R192-T196 WeakPolarHBondContact O-CB 3.35Å; R192-T196 PolarHBondContact O-N 3.26Å; R192-T196 PolarHBondContact O-OG1 2.82Å; R192-L263 HydrophobicContact CG-CD1 4.11Å; R192-L263 HydrophobicContact CG-CD2 4.35Å
193	L	94.1	Very high	93.1	Very high	17 Å²	17	71 Å²	71	9%	0.089	36%	0.359	C	S	.	.	H	α-helix	trans	-62.8	-49.8	174.6	176.3	62.9	0	0	0	111	L189 E190 Q195 T196 M197 S260 L263 F264	L189-L193 PolarHBondContact O-N 3.33Å; E190-L193 PolarHBondContact O-N 3.47Å; L193-Q195 PolarHBondContact O-N 2.92Å; L193-T196 WeakPolarHBondContact O-CB 3.5Å; L193-T196 PolarHBondContact O-N 2.95Å; L193-T196 VanDerWaalsContact O-N 3.12Å; L193-M197 HydrophobicContact CG-SD 4.5Å; L193-M197 WeakPolarHBondContact O-CG 3.49Å; L193-M197 PolarHBondContact O-N 2.73Å; L193-S260 WeakPolarHBondContact CD1-O 3.44Å; L193-L263 HydrophobicContact CB-CB 4.32Å; L193-L263 HydrophobicContact CD1-CB 3.84Å; L193-F264 HydrophobicContact CD1-CB 4.35Å; L193-F264 HydrophobicContact CD2-CB 4.37Å; L193-F264 HydrophobicContact CD2-CD2 4.25Å
194	L	95.3	Very high	93.3	Very high	105 Å²	105	71 Å²	71	55%	0.55	36%	0.355	S	S	.	.	H	α-helix	trans	-60.4	-45.4	178.3	-70.5	171.6	0	0	0	111.6	E190 R191 T196 M197 D198	E190-L194 WeakPolarHBondContact O-CG 3.5Å; E190-L194 PolarHBondContact O-N 2.83Å; R191-L194 PolarHBondContact O-N 3.42Å; L194-T196 VanDerWaalsContact C-N 3.27Å; L194-T196 PolarHBondContact O-N 3.31Å; L194-M197 WeakPolarHBondContact O-CB 3.29Å; L194-M197 PolarHBondContact O-N 2.9Å; L194-D198 PolarHBondContact O-N 2.95Å
195	Q	95.6	Very high	93.4	Very high	124 Å²	124	73.1 Å²	73.1	58%	0.579	36%	0.356	S	S	*	.	H	α-helix	trans	-58.3	-39.8	174.4	-74.8	172.1	-5.4	0	0	112.1	R191 L193 D198 M199	R191-Q195 WeakPolarHBondContact O-CB 3.34Å; R191-Q195 WeakPolarHBondContact O-CG 3.3Å; R191-Q195 PolarHBondContact O-N 3.41Å; L193-Q195 PolarHBondContact O-N 2.92Å; Q195-D198 PolarHBondContact O-N 2.83Å; Q195-M199 WeakPolarHBondContact O-CG 3.34Å; Q195-M199 PolarHBondContact O-N 2.88Å
196	T	93.9	Very high	93.4	Very high	5 Å²	5	78.9 Å²	78.9	3%	0.031	38%	0.375	C	S	.	.	H	α-helix	trans	-67.1	-42.7	177.4	-55.7	0	0	0	0	111.2	R192 L193 L194 D198 M199 I200 L256 L259 L263	R192-T196 WeakPolarHBondContact O-CB 3.35Å; R192-T196 PolarHBondContact O-N 3.26Å; R192-T196 PolarHBondContact O-OG1 2.82Å; L193-T196 WeakPolarHBondContact O-CB 3.5Å; L193-T196 PolarHBondContact O-N 2.95Å; L193-T196 VanDerWaalsContact O-N 3.12Å; L194-T196 VanDerWaalsContact C-N 3.27Å; L194-T196 PolarHBondContact O-N 3.31Å; T196-D198 PolarHBondContact O-N 3.03Å; T196-M199 HydrophobicContact CG2-CE 4.39Å; T196-M199 PolarHBondContact O-N 3.28Å; T196-I200 HydrophobicContact CG2-CD1 4.28Å; T196-I200 VanDerWaalsContact O-CG1 3.3Å; T196-I200 WeakPolarHBondContact O-CG1 3.45Å; T196-I200 PolarHBondContact O-N 3.22Å; T196-L256 HydrophobicContact CG2-CD2 4.23Å; T196-L259 HydrophobicContact CG2-CD2 4.16Å; T196-L259 HydrophobicContact CG2-CG 4.37Å; T196-L263 HydrophobicContact CG2-CD1 4.49Å
197	M	94.8	Very high	93.2	Very high	84 Å²	84	79.6 Å²	79.6	41%	0.414	38%	0.378	S	S	.	.	H	α-helix	trans	-60.5	-42.8	173.8	-71.9	-177.4	134.7	0	0	112	L193 L194 M199 I200 I201	L193-M197 HydrophobicContact CG-SD 4.5Å; L193-M197 WeakPolarHBondContact O-CG 3.49Å; L193-M197 PolarHBondContact O-N 2.73Å; L194-M197 WeakPolarHBondContact O-CB 3.29Å; L194-M197 PolarHBondContact O-N 2.9Å; M197-M199 VanDerWaalsContact C-N 3.35Å; M197-M199 PolarHBondContact O-N 2.89Å; M197-I200 WeakPolarHBondContact O-CB 3.43Å; M197-I200 PolarHBondContact O-N 3.48Å; M197-I201 VanDerWaalsContact O-CG1 3.28Å; M197-I201 WeakPolarHBondContact O-CG1 3.32Å; M197-I201 PolarHBondContact O-N 2.87Å
198	D	96.3	Very high	92.9	Very high	106 Å²	106	78.5 Å²	78.5	57%	0.567	38%	0.382	S	S	*	.	H	α-helix	trans	-62.4	-40.6	176.9	-74.4	-26.7	0	0	0	112.1	L194 Q195 T196 I201 S202	L194-D198 PolarHBondContact O-N 2.95Å; Q195-D198 PolarHBondContact O-N 2.83Å; T196-D198 PolarHBondContact O-N 3.03Å; D198-I201 PolarHBondContact O-N 3.44Å; D198-S202 VanDerWaalsContact O-CB 3.31Å; D198-S202 WeakPolarHBondContact O-CB 3.44Å; D198-S202 PolarHBondContact O-N 3.41Å
199	M	93.6	Very high	92.8	Very high	90 Å²	90	80.7 Å²	80.7	44%	0.443	38%	0.383	S	S	.	.	H	α-helix	trans	-62	-43.9	173.5	-70.9	-170.6	-62.1	0	0	111.9	Q195 T196 M197 S202 K203 L256	Q195-M199 WeakPolarHBondContact O-CG 3.34Å; Q195-M199 PolarHBondContact O-N 2.88Å; T196-M199 HydrophobicContact CG2-CE 4.39Å; T196-M199 PolarHBondContact O-N 3.28Å; M197-M199 VanDerWaalsContact C-N 3.35Å; M197-M199 PolarHBondContact O-N 2.89Å; M199-S202 PolarHBondContact O-N 3.36Å; M199-K203 WeakPolarHBondContact O-CG 3.38Å; M199-K203 PolarHBondContact O-N 3.43Å; M199-L256 HydrophobicContact CB-CD1 4.28Å; M199-L256 HydrophobicContact CE-CD2 3.91Å
200	I	94.5	Very high	92.4	Very high	15 Å²	15	81.3 Å²	81.3	8%	0.077	39%	0.391	C	S	.	.	H	α-helix	trans	-60.4	-49	176.9	-67	164.2	0	0	0	110.1	T196 M197 S202 K203 K204 L256 E257	T196-I200 HydrophobicContact CG2-CD1 4.28Å; T196-I200 VanDerWaalsContact O-CG1 3.3Å; T196-I200 WeakPolarHBondContact O-CG1 3.45Å; T196-I200 PolarHBondContact O-N 3.22Å; M197-I200 WeakPolarHBondContact O-CB 3.43Å; M197-I200 PolarHBondContact O-N 3.48Å; I200-S202 VanDerWaalsContact C-N 3.32Å; I200-S202 PolarHBondContact O-N 2.85Å; I200-K203 PolarHBondContact O-N 2.76Å; I200-K204 HydrophobicContact CG2-CD 4.03Å; I200-K204 HydrophobicContact CG2-CG 4.32Å; I200-K204 WeakPolarHBondContact O-CB 3.49Å; I200-K204 WeakPolarHBondContact O-CG 3.21Å; I200-K204 PolarHBondContact O-N 3.29Å; I200-L256 HydrophobicContact CD1-CB 4.09Å; I200-L256 HydrophobicContact CG1-CB 3.56Å; I200-L256 HydrophobicContact CG1-CD1 4.35Å; I200-E257 HydrophobicContact CD1-CG 4.28Å; I200-E257 HydrophobicContact CG2-CG 4.34Å
201	I	95.7	Very high	91.9	Very high	106 Å²	106	85.7 Å²	85.7	54%	0.544	41%	0.405	S	S	.	.	H	α-helix	trans	-59.7	-45.5	179.4	-68.2	165.6	0	0	0	110.2	M197 D198 K204 K205	M197-I201 VanDerWaalsContact O-CG1 3.28Å; M197-I201 WeakPolarHBondContact O-CG1 3.32Å; M197-I201 PolarHBondContact O-N 2.87Å; D198-I201 PolarHBondContact O-N 3.44Å; I201-K204 PolarHBondContact O-N 3.45Å; I201-K205 VanDerWaalsContact O-CB 3.3Å; I201-K205 WeakPolarHBondContact O-CB 3.2Å; I201-K205 PolarHBondContact O-N 3.33Å
202	S	93.9	Very high	91.3	Very high	52 Å²	52	86.1 Å²	86.1	36%	0.364	41%	0.407	S	S	.	.	H	α-helix	trans	-60.7	-46.4	178.1	-173.7	0	0	0	0	112.2	D198 M199 I200 K205 R206	D198-S202 VanDerWaalsContact O-CB 3.31Å; D198-S202 WeakPolarHBondContact O-CB 3.44Å; D198-S202 PolarHBondContact O-N 3.41Å; M199-S202 PolarHBondContact O-N 3.36Å; I200-S202 VanDerWaalsContact C-N 3.32Å; I200-S202 PolarHBondContact O-N 2.85Å; S202-K205 PolarHBondContact O-N 2.89Å; S202-R206 WeakPolarHBondContact O-CG 3.19Å; S202-R206 PolarHBondContact O-N 3.39Å
203	K	92.6	Very high	90.7	Very high	47 Å²	47	82.8 Å²	82.8	20%	0.204	40%	0.401	C	S	.	.	H	α-helix	trans	-67	-43.4	177.8	-70.4	-165.4	-179	-157.1	0	112.3	M199 I200 K205 R206 M207 I249 E252 V253 L256	M199-K203 WeakPolarHBondContact O-CG 3.38Å; M199-K203 PolarHBondContact O-N 3.43Å; I200-K203 PolarHBondContact O-N 2.76Å; K203-K205 VanDerWaalsContact C-N 3.31Å; K203-K205 PolarHBondContact O-N 3.09Å; K203-R206 WeakPolarHBondContact O-CB 3.33Å; K203-R206 PolarHBondContact O-N 2.98Å; K203-R206 VanDerWaalsContact O-N 3.15Å; K203-M207 WeakPolarHBondContact O-CG 3.36Å; K203-M207 PolarHBondContact O-N 3.27Å; K203-I249 HydrophobicContact CB-CG2 4.28Å; K203-E252 HydrophobicContact CD-CB 4.39Å; K203-E252 IonicContact NZ-OE1 2.72Å; K203-E252 PolarHBondContact NZ-OE1 3.01Å; K203-E252 IonicContact NZ-OE2 3.59Å; K203-E252 PolarHBondContact NZ-OE2 3.46Å; K203-V253 HydrophobicContact CB-CG2 3.67Å; K203-V253 HydrophobicContact CD-CG2 4.47Å; K203-L256 HydrophobicContact CD-CD1 3.98Å
204	K	92.6	Very high	89.8	Confident	92 Å²	92	85 Å²	85	40%	0.4	41%	0.412	S	S	.	.	H	α-helix	trans	-60	-40.5	173.7	-75.2	-172.4	175.3	-174.8	0	112.5	I200 I201 M207 A208 V253 E257	I200-K204 HydrophobicContact CG2-CD 4.03Å; I200-K204 HydrophobicContact CG2-CG 4.32Å; I200-K204 WeakPolarHBondContact O-CB 3.49Å; I200-K204 WeakPolarHBondContact O-CG 3.21Å; I200-K204 PolarHBondContact O-N 3.29Å; I201-K204 PolarHBondContact O-N 3.45Å; K204-M207 HydrophobicContact CG-CE 4.23Å; K204-M207 PolarHBondContact O-N 3.45Å; K204-A208 WeakPolarHBondContact O-CB 3.27Å; K204-A208 PolarHBondContact O-N 3.4Å; K204-V253 HydrophobicContact CG-CG1 4.09Å; K204-V253 HydrophobicContact CG-CG2 4.41Å; K204-E257 WeakPolarHBondContact CE-OE1 3.27Å; K204-E257 IonicContact NZ-OE1 2.82Å; K204-E257 PolarHBondContact NZ-OE1 2.96Å
205	K	92.4	Very high	88.7	Confident	139 Å²	139	87.6 Å²	87.6	60%	0.604	42%	0.419	S	S	*	.	H	α-helix	trans	-62.2	-43.9	174.3	-172.1	-177.8	177.6	179	0	111.3	I201 S202 K203 A208 M209	I201-K205 VanDerWaalsContact O-CB 3.3Å; I201-K205 WeakPolarHBondContact O-CB 3.2Å; I201-K205 PolarHBondContact O-N 3.33Å; S202-K205 PolarHBondContact O-N 2.89Å; K203-K205 VanDerWaalsContact C-N 3.31Å; K203-K205 PolarHBondContact O-N 3.09Å; K205-A208 PolarHBondContact O-N 3.13Å; K205-M209 HydrophobicContact CG-CE 4.1Å; K205-M209 HydrophobicContact CG-SD 4.49Å; K205-M209 WeakPolarHBondContact O-CG 3.34Å; K205-M209 PolarHBondContact O-N 2.88Å
206	R	88.1	Confident	87.5	Confident	156 Å²	156	86.6 Å²	86.6	59%	0.589	42%	0.415	S	S	*	.	H	α-helix	trans	-59.9	-45.5	174.7	-71.3	177.4	-171	-172.3	1.1	111.9	S202 K203 A208 M209 A210	S202-R206 WeakPolarHBondContact O-CG 3.19Å; S202-R206 PolarHBondContact O-N 3.39Å; K203-R206 WeakPolarHBondContact O-CB 3.33Å; K203-R206 PolarHBondContact O-N 2.98Å; K203-R206 VanDerWaalsContact O-N 3.15Å; R206-A208 PolarHBondContact O-N 3.18Å; R206-M209 HydrophobicContact CG-CE 4.42Å; R206-M209 PolarHBondContact O-N 3.37Å; R206-A210 WeakPolarHBondContact O-CB 3.34Å; R206-A210 PolarHBondContact O-N 2.97Å
207	M	86.4	Confident	86.1	Confident	19 Å²	19	92.2 Å²	92.2	9%	0.094	44%	0.439	C	S	.	.	H	α-helix	trans	-61	-43	175.9	-65.4	-164.9	-48.4	0	0	112.5	K203 K204 A210 R211 L246 I249 Q250 V253	K203-M207 WeakPolarHBondContact O-CG 3.36Å; K203-M207 PolarHBondContact O-N 3.27Å; K204-M207 HydrophobicContact CG-CE 4.23Å; K204-M207 PolarHBondContact O-N 3.45Å; M207-A210 PolarHBondContact O-N 2.82Å; M207-R211 WeakPolarHBondContact O-CB 3.3Å; M207-R211 WeakPolarHBondContact O-CG 3.2Å; M207-R211 PolarHBondContact O-N 3.42Å; M207-L246 HydrophobicContact CB-CD2 4.32Å; M207-L246 HydrophobicContact CG-CD2 4.37Å; M207-I249 HydrophobicContact CG-CB 4.26Å; M207-I249 HydrophobicContact CG-CG2 3.47Å; M207-I249 VanDerWaalsContact CG-CG2 3.47Å; M207-I249 HydrophobicContact SD-CB 4.41Å; M207-I249 HydrophobicContact SD-CG2 3.83Å; M207-Q250 HydrophobicContact SD-CB 4.28Å; M207-V253 HydrophobicContact CE-CG2 4.31Å; M207-V253 HydrophobicContact SD-CG2 4.46Å
208	A	87.2	Confident	84.4	Confident	62 Å²	62	90.4 Å²	90.4	51%	0.512	44%	0.441	S	S	.	.	H	α-helix	trans	-64.3	-41.3	178.2	0	0	0	0	0	111.8	K204 K205 R206 R212	K204-A208 WeakPolarHBondContact O-CB 3.27Å; K204-A208 PolarHBondContact O-N 3.4Å; K205-A208 PolarHBondContact O-N 3.13Å; R206-A208 PolarHBondContact O-N 3.18Å; A208-R212 WeakPolarHBondContact O-CB 3.14Å; A208-R212 PolarHBondContact O-N 3.44Å
209	M	88.2	Confident	82.3	Confident	102 Å²	102	92.8 Å²	92.8	50%	0.502	45%	0.449	S	S	.	.	H	α-helix	trans	-64.3	-46.9	174.4	-70.5	-172.9	-60.9	0	0	111.5	K205 R206 R211 R212 T213	K205-M209 HydrophobicContact CG-CE 4.1Å; K205-M209 HydrophobicContact CG-SD 4.49Å; K205-M209 WeakPolarHBondContact O-CG 3.34Å; K205-M209 PolarHBondContact O-N 2.88Å; R206-M209 HydrophobicContact CG-CE 4.42Å; R206-M209 PolarHBondContact O-N 3.37Å; M209-R211 PolarHBondContact O-N 3.09Å; M209-R212 WeakPolarHBondContact O-CB 3.36Å; M209-R212 PolarHBondContact O-N 3.3Å; M209-R212 VanDerWaalsContact O-N 3.11Å; M209-T213 PolarHBondContact O-N 3.08Å; M209-T213 PolarHBondContact O-OG1 3.45Å
210	A	83.4	Confident	80.3	Confident	31 Å²	31	94.3 Å²	94.3	26%	0.256	46%	0.463	S	S	.	.	H	α-helix	trans	-59.3	-45.7	177.9	0	0	0	0	0	112.3	R206 M207 R212 T213 M214 L246	R206-A210 WeakPolarHBondContact O-CB 3.34Å; R206-A210 PolarHBondContact O-N 2.97Å; M207-A210 PolarHBondContact O-N 2.82Å; A210-R212 VanDerWaalsContact C-N 3.34Å; A210-R212 PolarHBondContact O-N 2.85Å; A210-T213 WeakPolarHBondContact CA-OG1 3.26Å; A210-T213 PolarHBondContact O-N 3.13Å; A210-T213 PolarHBondContact O-OG1 3.49Å; A210-M214 WeakPolarHBondContact O-CG 3.46Å; A210-M214 PolarHBondContact O-N 2.99Å; A210-L246 HydrophobicContact CB-CD2 3.97Å
211	R	82.3	Confident	78.1	Confident	146 Å²	146	101.2 Å²	101.2	55%	0.551	49%	0.494	S	S	*	.	H	α-helix	trans	-58.8	-44.2	172.7	-77.2	-175.5	-177.9	-178	3.4	111.7	M207 M209 T213 M214 F215	M207-R211 WeakPolarHBondContact O-CB 3.3Å; M207-R211 WeakPolarHBondContact O-CG 3.2Å; M207-R211 PolarHBondContact O-N 3.42Å; M209-R211 PolarHBondContact O-N 3.09Å; R211-T213 PolarHBondContact O-N 3.36Å; R211-M214 WeakPolarHBondContact O-CB 3.21Å; R211-M214 PolarHBondContact O-N 3.36Å; R211-F215 VanDerWaalsContact O-CD2 3.25Å; R211-F215 WeakPolarHBondContact O-CD2 3.49Å; R211-F215 PolarHBondContact O-N 2.7Å
212	R	83	Confident	75.6	Confident	176 Å²	176	103.3 Å²	103.3	66%	0.664	51%	0.507	S	S	*	.	H	α-helix	trans	-61.8	-42.3	178.7	-171.4	177.3	-179.2	174.8	1	112.3	A208 M209 A210 F215 Q216	A208-R212 WeakPolarHBondContact O-CB 3.14Å; A208-R212 PolarHBondContact O-N 3.44Å; M209-R212 WeakPolarHBondContact O-CB 3.36Å; M209-R212 PolarHBondContact O-N 3.3Å; M209-R212 VanDerWaalsContact O-N 3.11Å; A210-R212 VanDerWaalsContact C-N 3.34Å; A210-R212 PolarHBondContact O-N 2.85Å; R212-F215 PolarHBondContact O-N 3.34Å; R212-Q216 PolarHBondContact O-N 2.93Å
213	T	80.6	Confident	73.3	Confident	64 Å²	64	109.5 Å²	109.5	39%	0.393	53%	0.527	S	S	.	.	H	α-helix	trans	-65	-36.1	174.1	29.5	0	0	0	0	112.9	M209 A210 R211 Q216 K217	M209-T213 PolarHBondContact O-N 3.08Å; M209-T213 PolarHBondContact O-OG1 3.45Å; A210-T213 WeakPolarHBondContact CA-OG1 3.26Å; A210-T213 PolarHBondContact O-N 3.13Å; A210-T213 PolarHBondContact O-OG1 3.49Å; R211-T213 PolarHBondContact O-N 3.36Å; T213-Q216 PolarHBondContact O-N 2.9Å; T213-K217 WeakPolarHBondContact O-CG 3.49Å; T213-K217 PolarHBondContact O-N 2.9Å
214	M	74.5	Confident	70.9	Confident	64 Å²	64	113.7 Å²	113.7	32%	0.315	56%	0.559	S	S	.	*	H	α-helix	trans	-63.9	-43.4	173.1	-72.9	-174	175.5	0	0	111.9	A210 R211 K217 G218 E242 L246	A210-M214 WeakPolarHBondContact O-CG 3.46Å; A210-M214 PolarHBondContact O-N 2.99Å; R211-M214 WeakPolarHBondContact O-CB 3.21Å; R211-M214 PolarHBondContact O-N 3.36Å; M214-K217 PolarHBondContact O-N 2.86Å; M214-G218 PolarHBondContact O-N 3.29Å; M214-E242 HydrophobicContact CE-CB 3.4Å; M214-E242 VanDerWaalsContact CE-CB 3.4Å; M214-L246 HydrophobicContact CE-CD1 3.5Å; M214-L246 HydrophobicContact SD-CD1 3.74Å
215	F	73.9	Confident	68.6	Low	160 Å²	160	113.7 Å²	113.7	70%	0.702	57%	0.571	S	S	*	*	H	α-helix	trans	-61.4	-43.4	174.9	-86.1	-74.8	0	0	0	112.2	R211 R212 G218 E219	R211-F215 VanDerWaalsContact O-CD2 3.25Å; R211-F215 WeakPolarHBondContact O-CD2 3.49Å; R211-F215 PolarHBondContact O-N 2.7Å; R212-F215 PolarHBondContact O-N 3.34Å; F215-G218 PolarHBondContact O-N 3.34Å; F215-E219 PolarHBondContact O-N 3.23Å; F215-E219 VanDerWaalsContact O-N 3.14Å
216	Q	70.4	Confident	66.5	Low	103 Å²	103	109.8 Å²	109.8	48%	0.481	57%	0.57	S	S	.	*	H	α-helix	trans	-65.7	-39.6	176.8	-75.5	-178.7	-26.6	0	0	112.9	R212 T213 G218 E219 V220	R212-Q216 PolarHBondContact O-N 2.93Å; T213-Q216 PolarHBondContact O-N 2.9Å; Q216-G218 VanDerWaalsContact C-N 3.31Å; Q216-E219 PolarHBondContact O-N 3.05Å; Q216-V220 WeakPolarHBondContact O-CG2 3.21Å; Q216-V220 PolarHBondContact O-N 3.47Å
217	K	64.3	Low	64.8	Low	123 Å²	123	110.7 Å²	110.7	54%	0.535	58%	0.579	S	S	.	*	H	α-helix	trans	-65.7	-34.5	173.1	-76.1	179.1	-177.9	173	0	111.8	T213 M214 V220 H221 E242	T213-K217 WeakPolarHBondContact O-CG 3.49Å; T213-K217 PolarHBondContact O-N 2.9Å; M214-K217 PolarHBondContact O-N 2.86Å; K217-V220 PolarHBondContact O-N 2.98Å; K217-H221 PolarHBondContact O-N 3.01Å; K217-E242 IonicContact NZ-OE1 2.64Å; K217-E242 PolarHBondContact NZ-OE1 3.04Å; K217-E242 VanDerWaalsContact NZ-OE1 3.1Å; K217-E242 IonicContact NZ-OE2 3.1Å
218	G	59	Low	63.1	Low	45 Å²	45	120.1 Å²	120.1	46%	0.464	61%	0.614	S	S	.	*	H	α-helix	trans	-65.3	-35	176.3	0	0	0	0	0	114	M214 F215 Q216	M214-G218 PolarHBondContact O-N 3.29Å; F215-G218 PolarHBondContact O-N 3.34Å; Q216-G218 VanDerWaalsContact C-N 3.31Å
219	E	52	Low	61.7	Low	157 Å²	157	118.9 Å²	118.9	73%	0.734	61%	0.607	S	S	*	*	H	α-helix	trans	-71	-32.4	174.9	-79.5	-174.4	143.4	0	0	113.1	F215 Q216 H221	F215-E219 PolarHBondContact O-N 3.23Å; F215-E219 VanDerWaalsContact O-N 3.14Å; Q216-E219 PolarHBondContact O-N 3.05Å; E219-H221 VanDerWaalsContact C-N 3.3Å; E219-H221 PolarHBondContact O-N 2.91Å
220	V	50.7	Low	60.1	Low	121 Å²	121	120.3 Å²	120.3	73%	0.733	61%	0.614	S	S	*	*	H	α-helix	trans	-72.6	-22.6	-179.9	178	0	0	0	0	112.4	Q216 K217	Q216-V220 WeakPolarHBondContact O-CG2 3.21Å; Q216-V220 PolarHBondContact O-N 3.47Å; K217-V220 PolarHBondContact O-N 2.98Å
221	H	47.9	Very low	58.8	Low	160 Å²	160	123.8 Å²	123.8	74%	0.741	63%	0.627	S	S	*	*	T	Hydrogen-bonded Turn	trans	-94.5	5.9	-178.9	-128.8	49.9	0	0	0	114.9	K217 E219 K223	K217-H221 PolarHBondContact O-N 3.01Å; E219-H221 VanDerWaalsContact C-N 3.3Å; E219-H221 PolarHBondContact O-N 2.91Å; H221-K223 PolarHBondContact O-N 2.7Å; H221-K223 VanDerWaalsContact O-N 3.17Å
222	N	45	Very low	57.3	Low	150 Å²	150	123.6 Å²	123.6	80%	0.802	63%	0.63	S	S	*	*			trans	-85.7	32.9	178.4	-119.4	1.5	0	0	0	113.6
223	K	44.7	Very low	55.8	Low	182 Å²	182	118.5 Å²	118.5	79%	0.791	62%	0.622	S	S	*	*	S	Bend	trans	-102.3	131.6	163.6	-90.5	-175.6	175.7	177.4	0	108.5	H221 S225	H221-K223 PolarHBondContact O-N 2.7Å; H221-K223 VanDerWaalsContact O-N 3.17Å; K223-S225 PolarHBondContact O-N 3.14Å
224	P	42.3	Very low	54.4	Low	135 Å²	135	120.4 Å²	120.4	88%	0.877	63%	0.633	S	S	*	*			trans	-75	94	-169.4	31.5	-33.3	0	0	0	109.8
225	S	43.7	Very low	53	Low	92 Å²	92	122.6 Å²	122.6	64%	0.643	65%	0.65	S	S	*	*			trans	-88.6	117.2	164.2	75.5	0	0	0	0	108.3	K223	K223-S225 PolarHBondContact O-N 3.14Å
226	G	48.6	Very low	51.5	Low	58 Å²	58	119.6 Å²	119.6	60%	0.598	65%	0.645	S	S	*	*			trans	-58.3	173.7	-170.3	0	0	0	0	0	115.8	W228 G229	G226-W228 PolarHBondContact O-N 3.44Å; G226-G229 PolarHBondContact O-N 3.38Å
227	F	52.5	Low	50.2	Low	174 Å²	174	119.1 Å²	119.1	76%	0.763	65%	0.653	S	S	*	*	T	Hydrogen-bonded Turn	trans	-32.7	-28.7	-174.2	-145	-102.7	0	0	0	117.4
228	W	51.6	Low	49.1	Very low	218 Å²	218	118.2 Å²	118.2	83%	0.826	67%	0.668	S	S	*	*	T	Hydrogen-bonded Turn	trans	-72.6	-22.8	176.1	-113.2	84.4	0	0	0	115.1	G226	G226-W228 PolarHBondContact O-N 3.44Å
229	G	57.1	Low	48.2	Very low	36 Å²	36	121.2 Å²	121.2	37%	0.371	68%	0.682	S	S	.	*	H	α-helix	trans	-74.2	-27.7	174.8	0	0	0	0	0	113.4	G226 S233	G226-G229 PolarHBondContact O-N 3.38Å; G229-S233 PolarHBondContact O-N 3.11Å
230	M	54.6	Low	47.9	Very low	132 Å²	132	117.2 Å²	117.2	65%	0.65	68%	0.683	S	S	*	*	H	α-helix	trans	-77.7	-21.1	-174.9	-157.3	167.2	91	0	0	113.4	S233 V234	M230-S233 PolarHBondContact O-OG 2.93Å; M230-S233 VanDerWaalsContact O-OG 3.04Å; M230-V234 WeakPolarHBondContact O-CG2 3.39Å
231	I	55.6	Low	47.7	Very low	103 Å²	103	115.6 Å²	115.6	53%	0.528	68%	0.677	S	S	.	*	H	α-helix	trans	-92.1	-26.3	-179.4	-37.7	176.6	0	0	0	110.7	T235	I231-T235 PolarHBondContact O-OG1 2.97Å
232	K	51.3	Low	48	Very low	143 Å²	143	112.6 Å²	112.6	62%	0.622	66%	0.664	S	S	*	*	H	α-helix	trans	-78.2	-27.1	175	-146	178.3	-175	-177.1	0	112.5	V234 T235 T236	K232-V234 VanDerWaalsContact C-N 3.32Å; K232-T235 PolarHBondContact O-OG1 2.94Å; K232-T236 PolarHBondContact O-N 3.36Å; K232-T236 PolarHBondContact O-OG1 2.8Å
233	S	52	Low	48.3	Very low	69 Å²	69	112 Å²	112	48%	0.483	66%	0.658	S	S	.	*	H	α-helix	trans	-72.2	-23.5	173	64	0	0	0	0	113.3	G229 M230 S237	G229-S233 PolarHBondContact O-N 3.11Å; M230-S233 PolarHBondContact O-OG 2.93Å; M230-S233 VanDerWaalsContact O-OG 3.04Å; S233-S237 PolarHBondContact O-OG 3.2Å; S233-S237 VanDerWaalsContact O-OG 3.1Å
234	V	51.9	Low	48.9	Very low	103 Å²	103	106.9 Å²	106.9	62%	0.624	64%	0.643	S	S	*	*	H	α-helix	trans	-82.2	-29.4	177.4	177.8	0	0	0	0	111.8	M230 K232 S237	M230-V234 WeakPolarHBondContact O-CG2 3.39Å; K232-V234 VanDerWaalsContact C-N 3.32Å; V234-S237 VanDerWaalsContact C-OG 3.29Å; V234-S237 PolarHBondContact O-OG 3.47Å
235	T	43.2	Very low	50.3	Low	111 Å²	111	105.2 Å²	105.2	68%	0.681	63%	0.626	S	S	*	*	H	α-helix	trans	-91.9	-8.4	-178.9	42	0	0	0	0	114.2	I231 K232	I231-T235 PolarHBondContact O-OG1 2.97Å; K232-T235 PolarHBondContact O-OG1 2.94Å
236	T	43.1	Very low	52	Low	96 Å²	96	102.2 Å²	102.2	59%	0.589	60%	0.603	S	S	*	*	T	Hydrogen-bonded Turn	trans	-109.8	28.9	170.8	47.4	0	0	0	0	112.7	K232 A238	K232-T236 PolarHBondContact O-N 3.36Å; K232-T236 PolarHBondContact O-OG1 2.8Å; T236-A238 PolarHBondContact O-N 3.39Å; T236-A238 VanDerWaalsContact O-N 3.07Å
237	S	42.8	Very low	53.7	Low	94 Å²	94	103.4 Å²	103.4	66%	0.657	60%	0.599	S	S	*	*	T	Hydrogen-bonded Turn	trans	-80.4	32.5	178.1	-43.1	0	0	0	0	113.8	S233 V234	S233-S237 PolarHBondContact O-OG 3.2Å; S233-S237 VanDerWaalsContact O-OG 3.1Å; V234-S237 VanDerWaalsContact C-OG 3.29Å; V234-S237 PolarHBondContact O-OG 3.47Å
238	A	41.4	Very low	55.4	Low	104 Å²	104	99.3 Å²	99.3	86%	0.86	58%	0.584	S	S	*	*	T	Hydrogen-bonded Turn	trans	-117	19.4	-177.5	0	0	0	0	0	113.5	T236	T236-A238 PolarHBondContact O-N 3.39Å; T236-A238 VanDerWaalsContact O-N 3.07Å
239	S	40.3	Very low	57	Low	107 Å²	107	90.2 Å²	90.2	75%	0.748	55%	0.552	S	S	*	*	S	Bend	trans	-145.4	103.4	173.1	57.1	0	0	0	0	112.4
240	G	46.3	Very low	58.6	Low	74 Å²	74	91.6 Å²	91.6	76%	0.763	55%	0.548	S	S	*	.			trans	72	68.8	150	0	0	0	0	0	116.7	E242	G240-E242 PolarHBondContact O-N 2.9Å
241	S	46.1	Very low	60.3	Low	86 Å²	86	91.8 Å²	91.8	60%	0.601	55%	0.548	S	S	*	.			trans	-68.2	116.7	155.4	48.6	0	0	0	0	108.2	M243 P244	S241-M243 PolarHBondContact O-N 3.21Å; S241-P244 WeakPolarHBondContact O-CD 3.46Å; S241-P244 VanDerWaalsContact O-CG 3.25Å; S241-P244 WeakPolarHBondContact O-CG 3.36Å; S241-P244 WeakPolarHBondContact OG-CD 3.44Å
242	E	53.5	Low	62	Low	98 Å²	98	90.6 Å²	90.6	46%	0.458	54%	0.54	S	S	.	.	S	Bend	trans	-66.2	2.7	171	-70.8	173.9	179.3	0	0	112.4	M214 K217 G240	M214-E242 HydrophobicContact CE-CB 3.4Å; M214-E242 VanDerWaalsContact CE-CB 3.4Å; K217-E242 IonicContact NZ-OE1 2.64Å; K217-E242 PolarHBondContact NZ-OE1 3.04Å; K217-E242 VanDerWaalsContact NZ-OE1 3.1Å; K217-E242 IonicContact NZ-OE2 3.1Å; G240-E242 PolarHBondContact O-N 2.9Å
243	M	51.3	Low	64	Low	138 Å²	138	83.8 Å²	83.8	68%	0.68	51%	0.51	S	S	*	.	H	α-helix	trans	-78.9	-44.8	-175.1	-150.5	-177.3	-68.1	0	0	113.9	S241 D245 L246 T247	S241-M243 PolarHBondContact O-N 3.21Å; M243-D245 VanDerWaalsContact C-N 3.27Å; M243-D245 PolarHBondContact O-N 3.36Å; M243-L246 PolarHBondContact O-N 2.99Å; M243-T247 PolarHBondContact O-N 3.44Å
244	P	56.9	Low	66	Low	74 Å²	74	84.1 Å²	84.1	48%	0.481	51%	0.507	S	S	.	.	H	α-helix	trans	-58.5	-30.9	171.2	15.4	-31.7	0	0	0	114.8	S241 T247 L248	S241-P244 WeakPolarHBondContact O-CD 3.46Å; S241-P244 VanDerWaalsContact O-CG 3.25Å; S241-P244 WeakPolarHBondContact O-CG 3.36Å; S241-P244 WeakPolarHBondContact OG-CD 3.44Å; P244-T247 WeakPolarHBondContact CA-OG1 3.36Å; P244-T247 PolarHBondContact O-OG1 3.49Å; P244-L248 WeakPolarHBondContact O-CB 3.46Å; P244-L248 PolarHBondContact O-N 2.89Å; P244-L248 VanDerWaalsContact O-N 3.16Å
245	D	71.9	Confident	68	Low	99 Å²	99	82.3 Å²	82.3	53%	0.529	50%	0.502	S	S	.	.	H	α-helix	trans	-69.8	-41.7	179.4	-164.8	23.4	0	0	0	111.5	M243 T247 L248 I249	M243-D245 VanDerWaalsContact C-N 3.27Å; M243-D245 PolarHBondContact O-N 3.36Å; D245-T247 PolarHBondContact O-N 3.38Å; D245-L248 PolarHBondContact O-N 2.84Å; D245-I249 VanDerWaalsContact O-CG1 3.24Å; D245-I249 WeakPolarHBondContact O-CG1 3.25Å; D245-I249 PolarHBondContact O-N 3.45Å
246	L	80.5	Confident	70.4	Confident	29 Å²	29	78.2 Å²	78.2	15%	0.152	48%	0.476	C	S	.	.	H	α-helix	trans	-63.6	-39.5	176.2	-82.3	167	0	0	0	113.1	M207 A210 M214 M243 Q250	M207-L246 HydrophobicContact CB-CD2 4.32Å; M207-L246 HydrophobicContact CG-CD2 4.37Å; A210-L246 HydrophobicContact CB-CD2 3.97Å; M214-L246 HydrophobicContact CE-CD1 3.5Å; M214-L246 HydrophobicContact SD-CD1 3.74Å; M243-L246 PolarHBondContact O-N 2.99Å; L246-Q250 WeakPolarHBondContact O-CB 3.41Å; L246-Q250 PolarHBondContact O-N 3.47Å
247	T	84.1	Confident	72.9	Confident	83 Å²	83	77.3 Å²	77.3	51%	0.509	47%	0.465	S	S	.	.	H	α-helix	trans	-69.2	-35.8	177.9	51.9	0	0	0	0	112	M243 P244 D245 Q250 Q251	M243-T247 PolarHBondContact O-N 3.44Å; P244-T247 WeakPolarHBondContact CA-OG1 3.36Å; P244-T247 PolarHBondContact O-OG1 3.49Å; D245-T247 PolarHBondContact O-N 3.38Å; T247-Q250 PolarHBondContact O-N 2.81Å; T247-Q251 WeakPolarHBondContact O-CG 3.47Å; T247-Q251 PolarHBondContact O-N 3.43Å; T247-Q251 VanDerWaalsContact O-N 3.08Å
248	L	87.8	Confident	75.3	Confident	88 Å²	88	76.3 Å²	76.3	46%	0.461	45%	0.45	S	S	.	.	H	α-helix	trans	-68.4	-46.9	176.4	-170.8	153.5	0	0	0	110.7	P244 D245 Q250 Q251 E252	P244-L248 WeakPolarHBondContact O-CB 3.46Å; P244-L248 PolarHBondContact O-N 2.89Å; P244-L248 VanDerWaalsContact O-N 3.16Å; D245-L248 PolarHBondContact O-N 2.84Å; L248-Q250 PolarHBondContact O-N 2.87Å; L248-Q251 PolarHBondContact O-N 3.41Å; L248-Q251 VanDerWaalsContact O-N 3.14Å; L248-E252 HydrophobicContact CD2-CG 4.07Å; L248-E252 WeakPolarHBondContact O-CG 3.09Å; L248-E252 PolarHBondContact O-N 3.44Å
249	I	85.7	Confident	77.7	Confident	28 Å²	28	74 Å²	74	14%	0.144	42%	0.423	C	S	.	.	H	α-helix	trans	-60.8	-36.1	175.8	-64.1	165.7	0	0	0	110.8	K203 M207 D245 E252 V253	K203-I249 HydrophobicContact CB-CG2 4.28Å; M207-I249 HydrophobicContact CG-CB 4.26Å; M207-I249 HydrophobicContact CG-CG2 3.47Å; M207-I249 VanDerWaalsContact CG-CG2 3.47Å; M207-I249 HydrophobicContact SD-CB 4.41Å; M207-I249 HydrophobicContact SD-CG2 3.83Å; D245-I249 VanDerWaalsContact O-CG1 3.24Å; D245-I249 WeakPolarHBondContact O-CG1 3.25Å; D245-I249 PolarHBondContact O-N 3.45Å; I249-E252 PolarHBondContact O-N 3.21Å; I249-V253 HydrophobicContact CG2-CG2 4.46Å; I249-V253 VanDerWaalsContact O-CG2 3.29Å; I249-V253 WeakPolarHBondContact O-CG2 3.4Å; I249-V253 PolarHBondContact O-N 2.92Å
250	Q	89.8	Confident	80.3	Confident	64 Å²	64	69.6 Å²	69.6	30%	0.299	39%	0.393	S	S	.	.	H	α-helix	trans	-62.9	-47	174.5	-176.3	65.1	47.2	0	0	111.7	M207 L246 T247 L248 E252 V253 D254	M207-Q250 HydrophobicContact SD-CB 4.28Å; L246-Q250 WeakPolarHBondContact O-CB 3.41Å; L246-Q250 PolarHBondContact O-N 3.47Å; T247-Q250 PolarHBondContact O-N 2.81Å; L248-Q250 PolarHBondContact O-N 2.87Å; Q250-E252 VanDerWaalsContact C-N 3.29Å; Q250-E252 PolarHBondContact O-N 3.44Å; Q250-V253 WeakPolarHBondContact O-CB 3.31Å; Q250-V253 PolarHBondContact O-N 2.9Å; Q250-V253 VanDerWaalsContact O-N 3.13Å; Q250-D254 PolarHBondContact NE2-OD1 2.94Å; Q250-D254 PolarHBondContact O-N 2.87Å
251	Q	91.1	Very high	82.4	Confident	137 Å²	137	72.9 Å²	72.9	64%	0.64	38%	0.382	S	S	*	.	H	α-helix	trans	-60.5	-39	176	-72.5	177.7	-12.6	0	0	112.1	T247 L248 D254 A255	T247-Q251 WeakPolarHBondContact O-CG 3.47Å; T247-Q251 PolarHBondContact O-N 3.43Å; T247-Q251 VanDerWaalsContact O-N 3.08Å; L248-Q251 PolarHBondContact O-N 3.41Å; L248-Q251 VanDerWaalsContact O-N 3.14Å; Q251-D254 PolarHBondContact O-N 3.4Å; Q251-A255 WeakPolarHBondContact O-CB 3.22Å; Q251-A255 PolarHBondContact O-N 3.07Å
252	E	91.9	Very high	84.6	Confident	77 Å²	77	73.7 Å²	73.7	36%	0.36	38%	0.376	S	S	.	.	H	α-helix	trans	-65.7	-38	174.5	-67.8	-177.5	132.6	0	0	112.5	K203 L248 I249 Q250 L256	K203-E252 HydrophobicContact CD-CB 4.39Å; K203-E252 IonicContact NZ-OE1 2.72Å; K203-E252 PolarHBondContact NZ-OE1 3.01Å; K203-E252 IonicContact NZ-OE2 3.59Å; K203-E252 PolarHBondContact NZ-OE2 3.46Å; L248-E252 HydrophobicContact CD2-CG 4.07Å; L248-E252 WeakPolarHBondContact O-CG 3.09Å; L248-E252 PolarHBondContact O-N 3.44Å; I249-E252 PolarHBondContact O-N 3.21Å; Q250-E252 VanDerWaalsContact C-N 3.29Å; Q250-E252 PolarHBondContact O-N 3.44Å; E252-L256 WeakPolarHBondContact O-CB 3.15Å; E252-L256 VanDerWaalsContact O-CG 3.24Å; E252-L256 WeakPolarHBondContact O-CG 3.33Å; E252-L256 PolarHBondContact O-N 3.5Å
253	V	93.4	Very high	86.4	Confident	0 Å²	0	69.2 Å²	69.2	0%	0	36%	0.356	C	S	.	.	H	α-helix	trans	-64.3	-46.5	174.4	168.3	0	0	0	0	110.1	K203 K204 M207 I249 Q250 A255 L256 E257	K203-V253 HydrophobicContact CB-CG2 3.67Å; K203-V253 HydrophobicContact CD-CG2 4.47Å; K204-V253 HydrophobicContact CG-CG1 4.09Å; K204-V253 HydrophobicContact CG-CG2 4.41Å; M207-V253 HydrophobicContact CE-CG2 4.31Å; M207-V253 HydrophobicContact SD-CG2 4.46Å; I249-V253 HydrophobicContact CG2-CG2 4.46Å; I249-V253 VanDerWaalsContact O-CG2 3.29Å; I249-V253 WeakPolarHBondContact O-CG2 3.4Å; I249-V253 PolarHBondContact O-N 2.92Å; Q250-V253 WeakPolarHBondContact O-CB 3.31Å; Q250-V253 PolarHBondContact O-N 2.9Å; Q250-V253 VanDerWaalsContact O-N 3.13Å; V253-A255 VanDerWaalsContact C-N 3.3Å; V253-A255 PolarHBondContact O-N 2.87Å; V253-L256 PolarHBondContact O-N 3.32Å; V253-L256 VanDerWaalsContact O-N 3.17Å; V253-E257 HydrophobicContact CG1-CG 4.28Å; V253-E257 WeakPolarHBondContact O-CB 2.96Å; V253-E257 WeakPolarHBondContact O-CG 3.49Å; V253-E257 PolarHBondContact O-N 2.98Å
254	D	93.4	Very high	88.4	Confident	77 Å²	77	68.6 Å²	68.6	41%	0.412	35%	0.349	S	S	.	.	H	α-helix	trans	-61	-40.6	179.2	-62	-17.7	0	0	0	111	Q250 Q251 E257 E258	Q250-D254 PolarHBondContact NE2-OD1 2.94Å; Q250-D254 PolarHBondContact O-N 2.87Å; Q251-D254 PolarHBondContact O-N 3.4Å; D254-E257 PolarHBondContact O-N 2.96Å; D254-E258 PolarHBondContact O-N 3.33Å; D254-E258 VanDerWaalsContact O-N 3.09Å
255	A	93.9	Very high	89.9	Confident	64 Å²	64	69.9 Å²	69.9	53%	0.529	35%	0.352	S	S	.	.	H	α-helix	trans	-65.6	-41.4	174.8	0	0	0	0	0	112.7	Q251 V253 E258 L259	Q251-A255 WeakPolarHBondContact O-CB 3.22Å; Q251-A255 PolarHBondContact O-N 3.07Å; V253-A255 VanDerWaalsContact C-N 3.3Å; V253-A255 PolarHBondContact O-N 2.87Å; A255-E258 PolarHBondContact O-N 3.23Å; A255-L259 PolarHBondContact O-N 2.85Å
256	L	93.7	Very high	90.7	Very high	25 Å²	25	68.4 Å²	68.4	13%	0.131	34%	0.341	C	S	.	.	H	α-helix	trans	-68.7	-35.1	176.4	-73.8	171.5	0	0	0	112.2	T196 M199 I200 K203 E252 V253 L259 S260	T196-L256 HydrophobicContact CG2-CD2 4.23Å; M199-L256 HydrophobicContact CB-CD1 4.28Å; M199-L256 HydrophobicContact CE-CD2 3.91Å; I200-L256 HydrophobicContact CD1-CB 4.09Å; I200-L256 HydrophobicContact CG1-CB 3.56Å; I200-L256 HydrophobicContact CG1-CD1 4.35Å; K203-L256 HydrophobicContact CD-CD1 3.98Å; E252-L256 WeakPolarHBondContact O-CB 3.15Å; E252-L256 VanDerWaalsContact O-CG 3.24Å; E252-L256 WeakPolarHBondContact O-CG 3.33Å; E252-L256 PolarHBondContact O-N 3.5Å; V253-L256 PolarHBondContact O-N 3.32Å; V253-L256 VanDerWaalsContact O-N 3.17Å; L256-L259 HydrophobicContact CD2-CD2 4.49Å; L256-L259 PolarHBondContact O-N 3.26Å; L256-S260 WeakPolarHBondContact O-CB 3.47Å; L256-S260 PolarHBondContact O-N 2.93Å
257	E	94.4	Very high	91.2	Very high	77 Å²	77	67.5 Å²	67.5	36%	0.36	34%	0.337	S	S	.	.	H	α-helix	trans	-63.8	-43	174.3	-77.2	-176.2	178.5	0	0	111.6	I200 K204 V253 D254 S260 R261	I200-E257 HydrophobicContact CD1-CG 4.28Å; I200-E257 HydrophobicContact CG2-CG 4.34Å; K204-E257 WeakPolarHBondContact CE-OE1 3.27Å; K204-E257 IonicContact NZ-OE1 2.82Å; K204-E257 PolarHBondContact NZ-OE1 2.96Å; V253-E257 HydrophobicContact CG1-CG 4.28Å; V253-E257 WeakPolarHBondContact O-CB 2.96Å; V253-E257 WeakPolarHBondContact O-CG 3.49Å; V253-E257 PolarHBondContact O-N 2.98Å; D254-E257 PolarHBondContact O-N 2.96Å; E257-S260 WeakPolarHBondContact O-CB 3.37Å; E257-S260 PolarHBondContact O-N 3.42Å; E257-R261 PolarHBondContact O-N 3.48Å
258	E	93.3	Very high	91.5	Very high	73 Å²	73	65.9 Å²	65.9	34%	0.341	33%	0.332	S	S	.	.	H	α-helix	trans	-64.7	-42.1	175	-177.7	55.8	-159	0	0	111.5	D254 A255 S260 R261 Q262	D254-E258 PolarHBondContact O-N 3.33Å; D254-E258 VanDerWaalsContact O-N 3.09Å; A255-E258 PolarHBondContact O-N 3.23Å; E258-S260 VanDerWaalsContact C-N 3.34Å; E258-S260 PolarHBondContact O-N 2.89Å; E258-R261 VanDerWaalsContact CD-NH2 3.33Å; E258-R261 WeakPolarHBondContact O-CB 3.32Å; E258-R261 PolarHBondContact O-N 3.5Å; E258-R261 IonicContact OE1-CZ 3.33Å; E258-R261 IonicContact OE1-NE 3.06Å; E258-R261 IonicContact OE1-NH2 3.34Å; E258-R261 PolarHBondContact OE1-NH2 2.62Å; E258-R261 IonicContact OE2-CZ 2.61Å; E258-R261 IonicContact OE2-NE 3.61Å; E258-R261 PolarHBondContact OE2-NE 3.32Å; E258-R261 IonicContact OE2-NH2 2.59Å; E258-R261 PolarHBondContact OE2-NH2 3.16Å; E258-Q262 WeakPolarHBondContact O-CG 3.41Å; E258-Q262 PolarHBondContact O-N 2.92Å; E258-Q262 PolarHBondContact OE1-NE2 3.07Å
259	L	92.8	Very high	91.5	Very high	56 Å²	56	65.9 Å²	65.9	29%	0.293	33%	0.333	S	S	.	.	H	α-helix	trans	-60.4	-43.3	172.8	178.8	64.4	0	0	0	111.6	T196 A255 L256 R261 Q262 L263	T196-L259 HydrophobicContact CG2-CD2 4.16Å; T196-L259 HydrophobicContact CG2-CG 4.37Å; A255-L259 PolarHBondContact O-N 2.85Å; L256-L259 HydrophobicContact CD2-CD2 4.49Å; L256-L259 PolarHBondContact O-N 3.26Å; L259-R261 VanDerWaalsContact C-N 3.29Å; L259-R261 PolarHBondContact O-N 3.45Å; L259-Q262 PolarHBondContact O-N 3.29Å; L259-L263 HydrophobicContact CD1-CD1 4.31Å; L259-L263 HydrophobicContact CD1-CG 4.23Å; L259-L263 HydrophobicContact CG-CD1 4Å; L259-L263 HydrophobicContact CG-CG 4.35Å; L259-L263 WeakPolarHBondContact O-CB 3.35Å; L259-L263 WeakPolarHBondContact O-CG 3.4Å; L259-L263 PolarHBondContact O-N 2.96Å
260	S	93.6	Very high	91.6	Very high	15 Å²	15	64.9 Å²	64.9	11%	0.105	33%	0.328	C	S	.	.	H	α-helix	trans	-61.3	-39.3	176.7	-178.9	0	0	0	0	111.6	L193 L256 E257 E258 F264	L193-S260 WeakPolarHBondContact CD1-O 3.44Å; L256-S260 WeakPolarHBondContact O-CB 3.47Å; L256-S260 PolarHBondContact O-N 2.93Å; E257-S260 WeakPolarHBondContact O-CB 3.37Å; E257-S260 PolarHBondContact O-N 3.42Å; E258-S260 VanDerWaalsContact C-N 3.34Å; E258-S260 PolarHBondContact O-N 2.89Å; S260-F264 VanDerWaalsContact O-CB 3.29Å; S260-F264 WeakPolarHBondContact O-CB 3.27Å; S260-F264 PolarHBondContact O-N 3.27Å
261	R	91.9	Very high	91.6	Very high	142 Å²	142	66.7 Å²	66.7	54%	0.536	33%	0.332	S	S	.	.	H	α-helix	trans	-64.4	-44	176.4	-169.6	176.1	72.9	116.2	5	111	E257 E258 L259 F264 L265	E257-R261 PolarHBondContact O-N 3.48Å; E258-R261 VanDerWaalsContact CD-NH2 3.33Å; E258-R261 WeakPolarHBondContact O-CB 3.32Å; E258-R261 PolarHBondContact O-N 3.5Å; E258-R261 IonicContact OE1-CZ 3.33Å; E258-R261 IonicContact OE1-NE 3.06Å; E258-R261 IonicContact OE1-NH2 3.34Å; E258-R261 PolarHBondContact OE1-NH2 2.62Å; E258-R261 IonicContact OE2-CZ 2.61Å; E258-R261 IonicContact OE2-NE 3.61Å; E258-R261 PolarHBondContact OE2-NE 3.32Å; E258-R261 IonicContact OE2-NH2 2.59Å; E258-R261 PolarHBondContact OE2-NH2 3.16Å; L259-R261 VanDerWaalsContact C-N 3.29Å; L259-R261 PolarHBondContact O-N 3.45Å; R261-F264 PolarHBondContact O-N 3.19Å; R261-L265 WeakPolarHBondContact O-CG 3.49Å; R261-L265 PolarHBondContact O-N 3.29Å
262	Q	91.3	Very high	91.5	Very high	104 Å²	104	61.8 Å²	61.8	49%	0.486	32%	0.316	S	S	.	.	H	α-helix	trans	-63.4	-48.5	176.6	-69.8	175.2	6.3	0	0	112	E258 L259 F264 L265 E266	E258-Q262 WeakPolarHBondContact O-CG 3.41Å; E258-Q262 PolarHBondContact O-N 2.92Å; E258-Q262 PolarHBondContact OE1-NE2 3.07Å; L259-Q262 PolarHBondContact O-N 3.29Å; Q262-F264 VanDerWaalsContact C-N 3.29Å; Q262-F264 PolarHBondContact O-N 2.94Å; Q262-L265 PolarHBondContact O-N 3.3Å; Q262-E266 WeakPolarHBondContact O-CB 3.35Å; Q262-E266 PolarHBondContact O-N 2.91Å
263	L	91.4	Very high	91.2	Very high	4 Å²	4	59 Å²	59	2%	0.021	30%	0.304	C	S	.	.	H	α-helix	trans	-60.8	-37.9	177.2	-71.9	173.7	0	0	0	112.2	L189 R192 L193 T196 L259 T267	L189-L263 HydrophobicContact CD1-CD2 3.64Å; R192-L263 HydrophobicContact CG-CD1 4.11Å; R192-L263 HydrophobicContact CG-CD2 4.35Å; L193-L263 HydrophobicContact CB-CB 4.32Å; L193-L263 HydrophobicContact CD1-CB 3.84Å; T196-L263 HydrophobicContact CG2-CD1 4.49Å; L259-L263 HydrophobicContact CD1-CD1 4.31Å; L259-L263 HydrophobicContact CD1-CG 4.23Å; L259-L263 HydrophobicContact CG-CD1 4Å; L259-L263 HydrophobicContact CG-CG 4.35Å; L259-L263 WeakPolarHBondContact O-CB 3.35Å; L259-L263 WeakPolarHBondContact O-CG 3.4Å; L259-L263 PolarHBondContact O-N 2.96Å; L263-T267 WeakPolarHBondContact O-CB 3.42Å; L263-T267 PolarHBondContact O-N 3.08Å; L263-T267 PolarHBondContact O-OG1 3.32Å
264	F	93.3	Very high	91	Very high	124 Å²	124	61.6 Å²	61.6	54%	0.544	32%	0.315	S	S	.	.	H	α-helix	trans	-64.6	-46.7	175.8	178.1	-96.7	0	0	0	111.9	L193 S260 R261 Q262 E266 T267 A268	L193-F264 HydrophobicContact CD1-CB 4.35Å; L193-F264 HydrophobicContact CD2-CB 4.37Å; L193-F264 HydrophobicContact CD2-CD2 4.25Å; S260-F264 VanDerWaalsContact O-CB 3.29Å; S260-F264 WeakPolarHBondContact O-CB 3.27Å; S260-F264 PolarHBondContact O-N 3.27Å; R261-F264 PolarHBondContact O-N 3.19Å; Q262-F264 VanDerWaalsContact C-N 3.29Å; Q262-F264 PolarHBondContact O-N 2.94Å; F264-E266 VanDerWaalsContact C-N 3.35Å; F264-E266 PolarHBondContact O-N 3.36Å; F264-T267 PolarHBondContact O-N 2.89Å; F264-A268 WeakPolarHBondContact O-CB 3.36Å; F264-A268 PolarHBondContact O-N 3.17Å
265	L	89.4	Confident	90.8	Very high	102 Å²	102	64.6 Å²	64.6	53%	0.534	33%	0.327	S	S	.	.	H	α-helix	trans	-62.7	-41.9	177	-70	172.5	0	0	0	111.7	R261 Q262 A268 D269	R261-L265 WeakPolarHBondContact O-CG 3.49Å; R261-L265 PolarHBondContact O-N 3.29Å; Q262-L265 PolarHBondContact O-N 3.3Å; L265-A268 PolarHBondContact O-N 3.47Å; L265-D269 WeakPolarHBondContact O-CB 3.37Å; L265-D269 PolarHBondContact O-N 2.93Å
266	E	89	Confident	90.4	Very high	67 Å²	67	67.7 Å²	67.7	31%	0.313	33%	0.325	S	S	.	.	H	α-helix	trans	-64.5	-40.5	176.2	-170.5	-178.2	-175.1	0	0	111.5	L189 Q262 F264 D269 L270	L189-E266 HydrophobicContact CD2-CB 3.88Å; L189-E266 HydrophobicContact CD2-CG 3.6Å; Q262-E266 WeakPolarHBondContact O-CB 3.35Å; Q262-E266 PolarHBondContact O-N 2.91Å; F264-E266 VanDerWaalsContact C-N 3.35Å; F264-E266 PolarHBondContact O-N 3.36Å; E266-D269 PolarHBondContact O-N 2.67Å; E266-L270 WeakPolarHBondContact O-CG 3.47Å; E266-L270 PolarHBondContact O-N 3.24Å
267	T	89.6	Confident	90	Very high	10 Å²	10	68 Å²	68	6%	0.061	33%	0.326	C	S	.	.	H	α-helix	trans	-62.8	-45.8	175.2	-55.7	0	0	0	0	111.1	L189 E190 L263 F264 D269 L270 Y271	L189-T267 WeakPolarHBondContact CD2-OG1 3.45Å; E190-T267 HydrophobicContact CG-CG2 3.87Å; L263-T267 WeakPolarHBondContact O-CB 3.42Å; L263-T267 PolarHBondContact O-N 3.08Å; L263-T267 PolarHBondContact O-OG1 3.32Å; F264-T267 PolarHBondContact O-N 2.89Å; T267-D269 VanDerWaalsContact C-N 3.3Å; T267-D269 PolarHBondContact O-N 2.8Å; T267-L270 PolarHBondContact O-N 3.16Å; T267-Y271 HydrophobicContact CG2-CD2 3.93Å; T267-Y271 HydrophobicContact CG2-CE2 3.85Å; T267-Y271 VanDerWaalsContact O-CD2 3.31Å; T267-Y271 WeakPolarHBondContact O-CD2 3.41Å; T267-Y271 PolarHBondContact O-N 2.94Å
268	A	90.8	Very high	89.7	Confident	50 Å²	50	69.3 Å²	69.3	41%	0.413	33%	0.332	S	S	.	.	H	α-helix	trans	-60.9	-39	176.1	0	0	0	0	0	112.2	F264 L265 Y271 A272	F264-A268 WeakPolarHBondContact O-CB 3.36Å; F264-A268 PolarHBondContact O-N 3.17Å; L265-A268 PolarHBondContact O-N 3.47Å; A268-Y271 PolarHBondContact O-N 3.01Å; A268-A272 WeakPolarHBondContact O-CB 3.33Å; A268-A272 PolarHBondContact O-N 3.41Å
269	D	87.6	Confident	89.5	Confident	87 Å²	87	70.4 Å²	70.4	47%	0.465	33%	0.334	S	S	.	.	H	α-helix	trans	-67.4	-39.3	176.5	-171.4	56.7	0	0	0	112.7	L265 E266 T267 A272 T273	L265-D269 WeakPolarHBondContact O-CB 3.37Å; L265-D269 PolarHBondContact O-N 2.93Å; E266-D269 PolarHBondContact O-N 2.67Å; T267-D269 VanDerWaalsContact C-N 3.3Å; T267-D269 PolarHBondContact O-N 2.8Å; D269-A272 PolarHBondContact O-N 3.18Å; D269-T273 WeakPolarHBondContact O-CB 3.37Å; D269-T273 PolarHBondContact O-N 2.56Å; D269-T273 PolarHBondContact O-OG1 3.17Å
270	L	87.9	Confident	89.2	Confident	8 Å²	8	69.3 Å²	69.3	4%	0.042	33%	0.331	C	S	.	.	H	α-helix	trans	-63.5	-41.8	173.7	-70.9	-176.6	0	0	0	111.9	V181 I186 L189 E266 T267 T273 K274	V181-L270 HydrophobicContact CG1-CB 4.27Å; V181-L270 HydrophobicContact CG1-CD2 3.93Å; V181-L270 HydrophobicContact CG2-CD2 3.71Å; I186-L270 HydrophobicContact CG1-CB 3.97Å; I186-L270 HydrophobicContact CG1-CD1 4.36Å; L189-L270 HydrophobicContact CB-CD1 4.44Å; L189-L270 HydrophobicContact CD2-CD1 3.69Å; L189-L270 HydrophobicContact CD2-CG 4.48Å; E266-L270 WeakPolarHBondContact O-CG 3.47Å; E266-L270 PolarHBondContact O-N 3.24Å; T267-L270 PolarHBondContact O-N 3.16Å; L270-T273 PolarHBondContact O-N 3.37Å; L270-K274 WeakPolarHBondContact O-CB 3.26Å; L270-K274 PolarHBondContact O-N 2.92Å
271	Y	90.6	Very high	88.9	Confident	101 Å²	101	75.6 Å²	75.6	40%	0.396	36%	0.356	S	S	.	.	H	α-helix	trans	-62.4	-45.6	173.8	-88	-69.2	0	0	0	112	I186 E190 T267 A268 T273 K274 E275	I186-Y271 HydrophobicContact CG2-CD2 4.21Å; I186-Y271 HydrophobicContact CG2-CE1 3.99Å; I186-Y271 HydrophobicContact CG2-CE2 3.54Å; I186-Y271 VanDerWaalsContact CG2-CZ 3.42Å; E190-Y271 WeakPolarHBondContact OE1-CE2 3.33Å; E190-Y271 VanDerWaalsContact OE1-CZ 3.26Å; E190-Y271 PolarHBondContact OE1-OH 2.99Å; T267-Y271 HydrophobicContact CG2-CD2 3.93Å; T267-Y271 HydrophobicContact CG2-CE2 3.85Å; T267-Y271 VanDerWaalsContact O-CD2 3.31Å; T267-Y271 WeakPolarHBondContact O-CD2 3.41Å; T267-Y271 PolarHBondContact O-N 2.94Å; A268-Y271 PolarHBondContact O-N 3.01Å; Y271-T273 VanDerWaalsContact C-N 3.27Å; Y271-T273 PolarHBondContact O-N 3.38Å; Y271-K274 PolarHBondContact O-N 3.39Å; Y271-E275 PolarHBondContact O-N 2.82Å
272	A	87.8	Confident	89	Confident	35 Å²	35	71.6 Å²	71.6	29%	0.289	35%	0.348	S	S	.	.	H	α-helix	trans	-61.3	-37.3	175.5	0	0	0	0	0	111.9	A268 D269 R276	A268-A272 WeakPolarHBondContact O-CB 3.33Å; A268-A272 PolarHBondContact O-N 3.41Å; D269-A272 PolarHBondContact O-N 3.18Å; A272-R276 WeakPolarHBondContact O-CG 3.25Å; A272-R276 PolarHBondContact O-N 3.41Å; A272-R276 VanDerWaalsContact O-N 3.13Å
273	T	85.8	Confident	89	Confident	18 Å²	18	75.7 Å²	75.7	11%	0.11	36%	0.364	C	S	.	.	H	α-helix	trans	-67.6	-42.8	175.9	-59.2	0	0	0	0	111.4	R179 V181 D269 L270 Y271 E275 R276 I277	R179-T273 HydrophobicContact CB-CG2 4.43Å; V181-T273 HydrophobicContact CG2-CG2 3.62Å; D269-T273 WeakPolarHBondContact O-CB 3.37Å; D269-T273 PolarHBondContact O-N 2.56Å; D269-T273 PolarHBondContact O-OG1 3.17Å; L270-T273 PolarHBondContact O-N 3.37Å; Y271-T273 VanDerWaalsContact C-N 3.27Å; Y271-T273 PolarHBondContact O-N 3.38Å; T273-E275 VanDerWaalsContact C-N 3.35Å; T273-E275 PolarHBondContact O-N 3.13Å; T273-R276 WeakPolarHBondContact O-CB 3.26Å; T273-R276 PolarHBondContact O-N 2.98Å; T273-R276 VanDerWaalsContact O-N 3.13Å; T273-I277 HydrophobicContact CG2-CD1 4.4Å; T273-I277 WeakPolarHBondContact O-CG1 3.29Å; T273-I277 PolarHBondContact O-N 2.96Å
274	K	88.9	Confident	88.9	Confident	55 Å²	55	81.6 Å²	81.6	24%	0.239	39%	0.39	C	S	.	.	H	α-helix	trans	-59.1	-45.1	174.8	-178.8	178.6	170.5	179.6	0	111.6	D183 I186 L270 Y271 R276 I277 E278	D183-K274 VanDerWaalsContact OD1-CE 3.25Å; D183-K274 WeakPolarHBondContact OD1-CE 3.39Å; D183-K274 IonicContact OD1-NZ 2.56Å; D183-K274 PolarHBondContact OD1-NZ 3.39Å; I186-K274 HydrophobicContact CD1-CB 4.13Å; I186-K274 HydrophobicContact CD1-CD 3.64Å; I186-K274 HydrophobicContact CD1-CG 4.45Å; L270-K274 WeakPolarHBondContact O-CB 3.26Å; L270-K274 PolarHBondContact O-N 2.92Å; Y271-K274 PolarHBondContact O-N 3.39Å; K274-R276 VanDerWaalsContact C-N 3.27Å; K274-R276 PolarHBondContact O-N 2.89Å; K274-I277 WeakPolarHBondContact O-CB 3.31Å; K274-I277 PolarHBondContact O-N 2.92Å; K274-I277 VanDerWaalsContact O-N 3.1Å; K274-E278 WeakPolarHBondContact CE-OE1 3.26Å; K274-E278 PolarHBondContact O-N 2.98Å
275	E	89.1	Confident	88.6	Confident	139 Å²	139	75.8 Å²	75.8	65%	0.65	37%	0.365	S	S	*	.	H	α-helix	trans	-58.5	-40.3	175.1	-171.3	-173.9	174.8	0	0	111.5	Y271 T273 E278 Y279	Y271-E275 PolarHBondContact O-N 2.82Å; T273-E275 VanDerWaalsContact C-N 3.35Å; T273-E275 PolarHBondContact O-N 3.13Å; E275-E278 PolarHBondContact O-N 3.4Å; E275-Y279 WeakPolarHBondContact O-CB 3.41Å; E275-Y279 PolarHBondContact O-N 3.39Å
276	R	85.6	Confident	88.6	Confident	129 Å²	129	77 Å²	77	49%	0.487	37%	0.367	S	S	.	.	H	α-helix	trans	-66.9	-37	175.2	-67.3	-177.2	-161.4	-167.6	10.1	112.9	L178 A272 T273 K274 Y279 S280	L178-R276 HydrophobicContact CD2-CB 3.69Å; A272-R276 WeakPolarHBondContact O-CG 3.25Å; A272-R276 PolarHBondContact O-N 3.41Å; A272-R276 VanDerWaalsContact O-N 3.13Å; T273-R276 WeakPolarHBondContact O-CB 3.26Å; T273-R276 PolarHBondContact O-N 2.98Å; T273-R276 VanDerWaalsContact O-N 3.13Å; K274-R276 VanDerWaalsContact C-N 3.27Å; K274-R276 PolarHBondContact O-N 2.89Å; R276-Y279 PolarHBondContact O-N 3.2Å; R276-S280 WeakPolarHBondContact O-CB 3.23Å; R276-S280 PolarHBondContact O-N 2.99Å
277	I	86.1	Confident	88.6	Confident	31 Å²	31	80.5 Å²	80.5	16%	0.159	38%	0.378	C	S	.	.	H	α-helix	trans	-62.3	-46.6	174.3	-67	168.7	0	0	0	109.4	L178 V181 T273 K274 S280 K281	L178-I277 HydrophobicContact CD2-CB 4.44Å; L178-I277 HydrophobicContact CD2-CG1 3.67Å; V181-I277 HydrophobicContact CB-CD1 4.27Å; T273-I277 HydrophobicContact CG2-CD1 4.4Å; T273-I277 WeakPolarHBondContact O-CG1 3.29Å; T273-I277 PolarHBondContact O-N 2.96Å; K274-I277 WeakPolarHBondContact O-CB 3.31Å; K274-I277 PolarHBondContact O-N 2.92Å; K274-I277 VanDerWaalsContact O-N 3.1Å; I277-S280 PolarHBondContact O-N 3.28Å; I277-S280 PolarHBondContact O-OG 3.45Å; I277-K281 PolarHBondContact O-N 3.19Å
278	E	88.9	Confident	88.4	Confident	105 Å²	105	82.5 Å²	82.5	49%	0.491	39%	0.386	S	S	.	.	H	α-helix	trans	-61.9	-43.9	176.3	-70	176.4	-171.2	0	0	111.6	K274 E275 S280 K281	K274-E278 WeakPolarHBondContact CE-OE1 3.26Å; K274-E278 PolarHBondContact O-N 2.98Å; E275-E278 PolarHBondContact O-N 3.4Å; E278-S280 VanDerWaalsContact C-N 3.31Å; E278-S280 PolarHBondContact O-N 3.48Å; E278-K281 WeakPolarHBondContact O-CB 3.47Å; E278-K281 PolarHBondContact O-N 3.47Å; E278-K281 VanDerWaalsContact O-N 3.16Å
279	Y	88.2	Confident	88.3	Confident	96 Å²	96	81.6 Å²	81.6	38%	0.376	37%	0.374	S	S	.	.	H	α-helix	trans	-57.8	-42.2	174	179	-99.9	0	0	0	112	E275 R276 K281 T282 K284 G285 F288	E275-Y279 WeakPolarHBondContact O-CB 3.41Å; E275-Y279 PolarHBondContact O-N 3.39Å; R276-Y279 PolarHBondContact O-N 3.2Å; Y279-K281 PolarHBondContact O-N 2.72Å; Y279-T282 WeakPolarHBondContact O-CB 3.42Å; Y279-T282 PolarHBondContact O-N 3.31Å; Y279-T282 VanDerWaalsContact O-N 3.07Å; Y279-T282 PolarHBondContact O-OG1 2.71Å; Y279-K284 HydrophobicContact CE2-CD 4.05Å; Y279-K284 HydrophobicContact CE2-CG 4.4Å; Y279-K284 WeakPolarHBondContact OH-CD 3.23Å; Y279-K284 VanDerWaalsContact OH-CE 3.31Å; Y279-K284 WeakPolarHBondContact OH-CE 3.42Å; Y279-K284 WeakPolarHBondContact OH-CG 3.37Å; Y279-G285 WeakPolarHBondContact O-CA 3.37Å; Y279-F288 WeakPolarHBondContact OH-CD2 3.07Å
280	S	86.5	Confident	88.3	Confident	33 Å²	33	84.5 Å²	84.5	23%	0.231	38%	0.383	C	S	.	.	H	α-helix	trans	-62	-28.6	180	79.7	0	0	0	0	113.2	R276 I277 E278 T282	R276-S280 WeakPolarHBondContact O-CB 3.23Å; R276-S280 PolarHBondContact O-N 2.99Å; I277-S280 PolarHBondContact O-N 3.28Å; I277-S280 PolarHBondContact O-OG 3.45Å; E278-S280 VanDerWaalsContact C-N 3.31Å; E278-S280 PolarHBondContact O-N 3.48Å; S280-T282 VanDerWaalsContact C-N 3.32Å
281	K	87.9	Confident	88	Confident	147 Å²	147	85.9 Å²	85.9	64%	0.639	39%	0.39	S	S	*	.	H	α-helix	trans	-74.5	-23.1	177.6	-65.7	173.2	-177.4	174.9	0	112.5	I277 E278 Y279	I277-K281 PolarHBondContact O-N 3.19Å; E278-K281 WeakPolarHBondContact O-CB 3.47Å; E278-K281 PolarHBondContact O-N 3.47Å; E278-K281 VanDerWaalsContact O-N 3.16Å; Y279-K281 PolarHBondContact O-N 2.72Å
282	T	93.3	Very high	87.8	Confident	59 Å²	59	81 Å²	81	36%	0.362	37%	0.371	S	S	.	.	S	Bend	trans	-67.7	157.8	178.3	73.1	0	0	0	0	111.9	Y279 S280 K284 G285 K286	Y279-T282 WeakPolarHBondContact O-CB 3.42Å; Y279-T282 PolarHBondContact O-N 3.31Å; Y279-T282 VanDerWaalsContact O-N 3.07Å; Y279-T282 PolarHBondContact O-OG1 2.71Å; S280-T282 VanDerWaalsContact C-N 3.32Å; T282-K284 PolarHBondContact O-N 3.29Å; T282-G285 PolarHBondContact O-N 2.96Å; T282-G285 VanDerWaalsContact O-N 3.09Å; T282-G285 PolarHBondContact OG1-N 2.95Å; T282-K286 WeakPolarHBondContact O-CG 3.09Å; T282-K286 PolarHBondContact O-N 3.49Å
283	F	91.3	Very high	87.7	Confident	189 Å²	189	84.2 Å²	84.2	83%	0.829	38%	0.376	S	S	*	.	H	α-helix	trans	-56.8	-39.5	174.5	-72.8	-76.9	0	0	0	112.6	K286 Y287	F283-K286 PolarHBondContact O-N 2.98Å; F283-Y287 PolarHBondContact O-N 2.97Å; F283-Y287 VanDerWaalsContact O-N 3.1Å
284	K	88.4	Confident	87.8	Confident	128 Å²	128	89.4 Å²	89.4	56%	0.557	40%	0.397	S	S	*	.	H	α-helix	trans	-63.6	-44.3	175.2	-170.7	-178.3	174.4	-173.6	0	110.9	Y279 T282 Y287 F288	Y279-K284 HydrophobicContact CE2-CD 4.05Å; Y279-K284 HydrophobicContact CE2-CG 4.4Å; Y279-K284 WeakPolarHBondContact OH-CD 3.23Å; Y279-K284 VanDerWaalsContact OH-CE 3.31Å; Y279-K284 WeakPolarHBondContact OH-CE 3.42Å; Y279-K284 WeakPolarHBondContact OH-CG 3.37Å; T282-K284 PolarHBondContact O-N 3.29Å; K284-Y287 PolarHBondContact O-N 3.43Å; K284-F288 HydrophobicContact CD-CE2 4.38Å; K284-F288 HydrophobicContact CG-CD2 3.93Å; K284-F288 HydrophobicContact CG-CE2 3.77Å; K284-F288 VanDerWaalsContact O-CD2 3.24Å; K284-F288 WeakPolarHBondContact O-CD2 3.49Å; K284-F288 PolarHBondContact O-N 3.19Å
285	G	87.8	Confident	87.4	Confident	3 Å²	3	90.7 Å²	90.7	3%	0.031	40%	0.403	C	S	.	.	H	α-helix	trans	-59.3	-46.8	175.2	0	0	0	0	0	112.9	Y279 T282 Y287 F288 N289	Y279-G285 WeakPolarHBondContact O-CA 3.37Å; T282-G285 PolarHBondContact O-N 2.96Å; T282-G285 VanDerWaalsContact O-N 3.09Å; T282-G285 PolarHBondContact OG1-N 2.95Å; G285-Y287 VanDerWaalsContact C-N 3.32Å; G285-Y287 PolarHBondContact O-N 2.91Å; G285-F288 PolarHBondContact O-N 3.47Å; G285-N289 WeakPolarHBondContact O-CB 3.34Å; G285-N289 PolarHBondContact O-N 2.91Å
286	K	88.7	Confident	87.3	Confident	128 Å²	128	85.7 Å²	85.7	56%	0.557	38%	0.384	S	S	*	.	H	α-helix	trans	-58.9	-41.5	176.4	-69.3	-179.3	-177.6	-178.7	0	112.5	T282 F283 N289 F290	T282-K286 WeakPolarHBondContact O-CG 3.09Å; T282-K286 PolarHBondContact O-N 3.49Å; F283-K286 PolarHBondContact O-N 2.98Å; K286-N289 PolarHBondContact O-N 3.24Å; K286-F290 PolarHBondContact O-N 3.39Å
287	Y	90.1	Very high	87.4	Confident	139 Å²	139	85.6 Å²	85.6	55%	0.545	39%	0.391	S	S	.	.	H	α-helix	trans	-62.5	-47.8	175.1	173.5	-100.6	0	0	0	112.4	F283 K284 G285 N289 F290 L291	F283-Y287 PolarHBondContact O-N 2.97Å; F283-Y287 VanDerWaalsContact O-N 3.1Å; K284-Y287 PolarHBondContact O-N 3.43Å; G285-Y287 VanDerWaalsContact C-N 3.32Å; G285-Y287 PolarHBondContact O-N 2.91Å; Y287-N289 VanDerWaalsContact C-N 3.3Å; Y287-N289 PolarHBondContact O-N 3.01Å; Y287-F290 PolarHBondContact O-N 3.05Å; Y287-L291 HydrophobicContact CD1-CD1 3.95Å; Y287-L291 HydrophobicContact CE1-CD1 3.28Å; Y287-L291 HydrophobicContact CE1-CG 4.1Å; Y287-L291 HydrophobicContact CE2-CD1 4.37Å; Y287-L291 HydrophobicContact CE2-CG 4.4Å; Y287-L291 PolarHBondContact O-N 3.19Å
288	F	84.9	Confident	87.4	Confident	52 Å²	52	89.6 Å²	89.6	23%	0.228	41%	0.405	C	S	.	.	H	α-helix	trans	-65.6	-33	177	-81.8	-72.8	0	0	0	112.7	Y173 Y279 K284 G285 L291 G292	Y173-F288 HydrophobicContact CD1-CB 4.49Å; Y173-F288 HydrophobicContact CD1-CD1 4.38Å; Y173-F288 HydrophobicContact CE1-CD1 4.18Å; Y173-F288 HydrophobicContact CE2-CD1 4.49Å; Y279-F288 WeakPolarHBondContact OH-CD2 3.07Å; K284-F288 HydrophobicContact CD-CE2 4.38Å; K284-F288 HydrophobicContact CG-CD2 3.93Å; K284-F288 HydrophobicContact CG-CE2 3.77Å; K284-F288 VanDerWaalsContact O-CD2 3.24Å; K284-F288 WeakPolarHBondContact O-CD2 3.49Å; K284-F288 PolarHBondContact O-N 3.19Å; G285-F288 PolarHBondContact O-N 3.47Å; F288-L291 HydrophobicContact CD1-CD1 4.29Å; F288-L291 PolarHBondContact O-N 3.23Å; F288-G292 PolarHBondContact O-N 3.47Å
289	N	88.3	Confident	87.4	Confident	32 Å²	32	85.1 Å²	85.1	17%	0.171	39%	0.386	C	S	.	.	H	α-helix	trans	-63.2	-47.2	173.8	-171.2	37.6	0	0	0	111.5	Y173 M174 S175 G285 K286 Y287 L291 G292 Y293	Y173-N289 WeakPolarHBondContact O-CA 3.5Å; M174-N289 WeakPolarHBondContact CA-OD1 3.45Å; S175-N289 PolarHBondContact N-OD1 2.98Å; S175-N289 PolarHBondContact OG-ND2 2.76Å; S175-N289 PolarHBondContact OG-OD1 3.17Å; G285-N289 WeakPolarHBondContact O-CB 3.34Å; G285-N289 PolarHBondContact O-N 2.91Å; K286-N289 PolarHBondContact O-N 3.24Å; Y287-N289 VanDerWaalsContact C-N 3.3Å; Y287-N289 PolarHBondContact O-N 3.01Å; N289-L291 PolarHBondContact O-N 3.42Å; N289-G292 WeakPolarHBondContact O-CA 3.36Å; N289-G292 PolarHBondContact O-N 3.48Å; N289-Y293 VanDerWaalsContact O-CD2 3.23Å; N289-Y293 WeakPolarHBondContact O-CD2 3.48Å; N289-Y293 PolarHBondContact O-N 3.24Å
290	F	88.8	Confident	87.4	Confident	147 Å²	147	85.2 Å²	85.2	65%	0.645	40%	0.396	S	S	*	.	H	α-helix	trans	-59	-45.8	174.4	176.7	-100.5	0	0	0	112	K286 Y287 G292 Y293 F294	K286-F290 PolarHBondContact O-N 3.39Å; Y287-F290 PolarHBondContact O-N 3.05Å; F290-G292 PolarHBondContact O-N 3.44Å; F290-Y293 PolarHBondContact O-N 2.95Å; F290-F294 PolarHBondContact O-N 2.88Å
291	L	81.8	Confident	87.5	Confident	37 Å²	37	90.6 Å²	90.6	19%	0.194	41%	0.411	C	S	.	.	H	α-helix	trans	-59.4	-36.6	172.7	-76.2	180	0	0	0	112.3	Y287 F288 N289 Y293 F294 F295	Y287-L291 HydrophobicContact CD1-CD1 3.95Å; Y287-L291 HydrophobicContact CE1-CD1 3.28Å; Y287-L291 HydrophobicContact CE1-CG 4.1Å; Y287-L291 HydrophobicContact CE2-CD1 4.37Å; Y287-L291 HydrophobicContact CE2-CG 4.4Å; Y287-L291 PolarHBondContact O-N 3.19Å; F288-L291 HydrophobicContact CD1-CD1 4.29Å; F288-L291 PolarHBondContact O-N 3.23Å; N289-L291 PolarHBondContact O-N 3.42Å; L291-Y293 VanDerWaalsContact C-N 3.33Å; L291-Y293 PolarHBondContact O-N 3.31Å; L291-F294 PolarHBondContact O-N 2.78Å; L291-F295 HydrophobicContact CB-CD2 4.28Å; L291-F295 HydrophobicContact CB-CE2 4.36Å; L291-F295 WeakPolarHBondContact O-CB 2.99Å; L291-F295 WeakPolarHBondContact O-CD2 3.5Å; L291-F295 PolarHBondContact O-N 3.44Å
292	G	84.9	Confident	87.4	Confident	0 Å²	0	85.8 Å²	85.8	0%	0	39%	0.39	C	S	.	.	H	α-helix	trans	-56.7	-44.6	176	0	0	0	0	0	112.3	F288 N289 F290 F295 S296	F288-G292 PolarHBondContact O-N 3.47Å; N289-G292 WeakPolarHBondContact O-CA 3.36Å; N289-G292 PolarHBondContact O-N 3.48Å; F290-G292 PolarHBondContact O-N 3.44Å; G292-F295 PolarHBondContact O-N 3Å; G292-S296 WeakPolarHBondContact O-CB 3.34Å; G292-S296 PolarHBondContact O-N 3.39Å
293	Y	87.1	Confident	87.2	Confident	101 Å²	101	84.5 Å²	84.5	40%	0.396	38%	0.381	S	S	.	.	H	α-helix	trans	-64	-45	174.9	-73.3	-74.8	0	0	0	112.6	M174 N289 F290 L291 S296 I297	M174-Y293 HydrophobicContact CE-CD1 3.77Å; M174-Y293 HydrophobicContact CE-CE1 3.48Å; M174-Y293 VanDerWaalsContact CE-CE1 3.48Å; N289-Y293 VanDerWaalsContact O-CD2 3.23Å; N289-Y293 WeakPolarHBondContact O-CD2 3.48Å; N289-Y293 PolarHBondContact O-N 3.24Å; F290-Y293 PolarHBondContact O-N 2.95Å; L291-Y293 VanDerWaalsContact C-N 3.33Å; L291-Y293 PolarHBondContact O-N 3.31Å; Y293-S296 WeakPolarHBondContact O-CB 3.1Å; Y293-S296 PolarHBondContact O-N 2.96Å; Y293-I297 WeakPolarHBondContact O-CG1 3.25Å; Y293-I297 PolarHBondContact O-N 3.11Å; Y293-I297 VanDerWaalsContact O-N 3.12Å
294	F	86.5	Confident	87.2	Confident	128 Å²	128	80.9 Å²	80.9	56%	0.561	37%	0.365	S	S	*	.	H	α-helix	trans	-60.3	-47.7	176.4	178	-95	0	0	0	111.8	F290 L291 S296 I297 Y298	F290-F294 PolarHBondContact O-N 2.88Å; L291-F294 PolarHBondContact O-N 2.78Å; F294-S296 VanDerWaalsContact C-N 3.3Å; F294-S296 PolarHBondContact O-N 2.82Å; F294-I297 PolarHBondContact O-N 3.01Å; F294-Y298 PolarHBondContact O-N 3.21Å; F294-Y298 VanDerWaalsContact O-N 3.09Å
295	F	80.9	Confident	87	Confident	82 Å²	82	77.4 Å²	77.4	36%	0.36	35%	0.351	S	S	.	.	H	α-helix	trans	-63.3	-36.3	176.4	-81.4	-60.4	0	0	0	112.1	L291 G292 Y298 C299	L291-F295 HydrophobicContact CB-CD2 4.28Å; L291-F295 HydrophobicContact CB-CE2 4.36Å; L291-F295 WeakPolarHBondContact O-CB 2.99Å; L291-F295 WeakPolarHBondContact O-CD2 3.5Å; L291-F295 PolarHBondContact O-N 3.44Å; G292-F295 PolarHBondContact O-N 3Å; F295-Y298 PolarHBondContact O-N 2.82Å; F295-C299 VanDerWaalsContact O-CB 3.29Å; F295-C299 WeakPolarHBondContact O-CB 3.39Å; F295-C299 PolarHBondContact O-N 3.46Å; F295-C299 PolarHBondContact O-SG 2.86Å
296	S	87.2	Confident	86.9	Confident	34 Å²	34	77.4 Å²	77.4	24%	0.238	35%	0.351	C	S	.	.	H	α-helix	trans	-58.7	-49.4	175.7	-175.4	0	0	0	0	111.6	G292 Y293 F294 Y298 C299 V300	G292-S296 WeakPolarHBondContact O-CB 3.34Å; G292-S296 PolarHBondContact O-N 3.39Å; Y293-S296 WeakPolarHBondContact O-CB 3.1Å; Y293-S296 PolarHBondContact O-N 2.96Å; F294-S296 VanDerWaalsContact C-N 3.3Å; F294-S296 PolarHBondContact O-N 2.82Å; S296-Y298 VanDerWaalsContact C-N 3.33Å; S296-Y298 PolarHBondContact O-N 3.3Å; S296-C299 PolarHBondContact O-N 3.4Å; S296-V300 WeakPolarHBondContact O-CG2 3.36Å; S296-V300 PolarHBondContact O-N 3.45Å
297	I	88.1	Confident	87	Confident	126 Å²	126	73.9 Å²	73.9	65%	0.646	34%	0.34	S	S	*	.	H	α-helix	trans	-58.5	-47.2	176.7	-64.2	167.7	0	0	0	110.4	Y293 F294 C299 V300 W301	Y293-I297 WeakPolarHBondContact O-CG1 3.25Å; Y293-I297 PolarHBondContact O-N 3.11Å; Y293-I297 VanDerWaalsContact O-N 3.12Å; F294-I297 PolarHBondContact O-N 3.01Å; I297-C299 PolarHBondContact O-N 3.31Å; I297-V300 PolarHBondContact O-N 3.42Å; I297-W301 WeakPolarHBondContact O-CB 3.2Å; I297-W301 PolarHBondContact O-N 3Å
298	Y	85.5	Confident	86.8	Confident	115 Å²	115	69 Å²	69	45%	0.451	32%	0.323	S	S	.	.	H	α-helix	trans	-60.6	-42.2	177	171.5	-100.8	0	0	0	112.7	F294 F295 S296 W301 K302	F294-Y298 PolarHBondContact O-N 3.21Å; F294-Y298 VanDerWaalsContact O-N 3.09Å; F295-Y298 PolarHBondContact O-N 2.82Å; S296-Y298 VanDerWaalsContact C-N 3.33Å; S296-Y298 PolarHBondContact O-N 3.3Å; Y298-W301 PolarHBondContact O-N 3.09Å; Y298-K302 HydrophobicContact CE1-CD 4.24Å; Y298-K302 VanDerWaalsContact O-CB 3.32Å; Y298-K302 WeakPolarHBondContact O-CB 3.2Å; Y298-K302 PolarHBondContact O-N 3.02Å
299	C	88.3	Confident	86.9	Confident	12 Å²	12	68.6 Å²	68.6	8%	0.081	32%	0.323	C	S	.	.	H	α-helix	trans	-67.8	-42.6	-179.6	-72.1	0	0	0	0	111.9	A166 F295 S296 I297 K302 I303	A166-C299 VanDerWaalsContact CA-SG 3.52Å; A166-C299 HydrophobicContact CB-CB 4.13Å; A166-C299 VanDerWaalsContact O-CB 3.3Å; A166-C299 WeakPolarHBondContact O-CB 3.43Å; A166-C299 PolarHBondContact O-SG 2.94Å; F295-C299 VanDerWaalsContact O-CB 3.29Å; F295-C299 WeakPolarHBondContact O-CB 3.39Å; F295-C299 PolarHBondContact O-N 3.46Å; F295-C299 PolarHBondContact O-SG 2.86Å; S296-C299 PolarHBondContact O-N 3.4Å; I297-C299 PolarHBondContact O-N 3.31Å; C299-K302 PolarHBondContact O-N 3.33Å; C299-I303 WeakPolarHBondContact O-CB 3.39Å; C299-I303 VanDerWaalsContact O-CG1 3.29Å; C299-I303 WeakPolarHBondContact O-CG1 3.39Å; C299-I303 PolarHBondContact O-N 2.91Å
300	V	90.1	Very high	86.9	Confident	97 Å²	97	69.1 Å²	69.1	59%	0.588	33%	0.326	S	S	*	.	H	α-helix	trans	-60.7	-47	173.3	172.5	0	0	0	0	110.4	S296 I297 K302 I303 F304	S296-V300 WeakPolarHBondContact O-CG2 3.36Å; S296-V300 PolarHBondContact O-N 3.45Å; I297-V300 PolarHBondContact O-N 3.42Å; V300-K302 PolarHBondContact O-N 3.16Å; V300-I303 PolarHBondContact O-N 2.98Å; V300-F304 WeakPolarHBondContact O-CB 3.38Å; V300-F304 PolarHBondContact O-N 2.55Å
301	W	88	Confident	86.9	Confident	147 Å²	147	67 Å²	67	56%	0.557	33%	0.325	S	S	*	.	H	α-helix	trans	-59.4	-43.8	175.6	176.1	-100.9	0	0	0	112.6	I297 Y298 F304 M305	I297-W301 WeakPolarHBondContact O-CB 3.2Å; I297-W301 PolarHBondContact O-N 3Å; Y298-W301 PolarHBondContact O-N 3.09Å; W301-F304 HydrophobicContact CE3-CD1 4.47Å; W301-F304 PolarHBondContact O-N 2.91Å; W301-M305 HydrophobicContact CD2-CE 4.49Å; W301-M305 HydrophobicContact CD2-CG 4.3Å; W301-M305 HydrophobicContact CH2-CE 3.29Å; W301-M305 HydrophobicContact CZ2-CE 3.09Å; W301-M305 HydrophobicContact CZ2-CG 4.24Å; W301-M305 HydrophobicContact CZ2-SD 4.48Å; W301-M305 HydrophobicContact CZ3-CE 4.07Å; W301-M305 WeakPolarHBondContact O-CB 3.46Å; W301-M305 WeakPolarHBondContact O-CG 3.39Å; W301-M305 PolarHBondContact O-N 3.3Å
302	K	85.4	Confident	87	Confident	46 Å²	46	72.4 Å²	72.4	20%	0.2	35%	0.347	C	S	.	.	H	α-helix	trans	-65.5	-42	179	-171.9	177.6	178.8	-179.6	0	111.8	S162 Y298 C299 V300 M305 A306 F432	S162-K302 PolarHBondContact OG-NZ 3.07Å; S162-K302 VanDerWaalsContact OG-NZ 3.11Å; Y298-K302 HydrophobicContact CE1-CD 4.24Å; Y298-K302 VanDerWaalsContact O-CB 3.32Å; Y298-K302 WeakPolarHBondContact O-CB 3.2Å; Y298-K302 PolarHBondContact O-N 3.02Å; C299-K302 PolarHBondContact O-N 3.33Å; V300-K302 PolarHBondContact O-N 3.16Å; K302-M305 PolarHBondContact O-N 3.21Å; K302-A306 WeakPolarHBondContact O-CB 3.24Å; K302-A306 PolarHBondContact O-N 2.65Å; K302-F432 HydrophobicContact CB-CZ 4.41Å; K302-F432 HydrophobicContact CD-CE1 4.3Å; K302-F432 HydrophobicContact CD-CE2 4.06Å; K302-F432 HydrophobicContact CD-CZ 3.7Å; K302-F432 HydrophobicContact CG-CE1 3.98Å; K302-F432 HydrophobicContact CG-CZ 3.82Å
303	I	89.6	Confident	86.6	Confident	32 Å²	32	76.8 Å²	76.8	16%	0.164	37%	0.37	C	S	.	.	H	α-helix	trans	-59.9	-48.5	173.8	-71.2	167.9	0	0	0	109.8	C299 V300 M305 A306 T307 F432 L433 A436	C299-I303 WeakPolarHBondContact O-CB 3.39Å; C299-I303 VanDerWaalsContact O-CG1 3.29Å; C299-I303 WeakPolarHBondContact O-CG1 3.39Å; C299-I303 PolarHBondContact O-N 2.91Å; V300-I303 PolarHBondContact O-N 2.98Å; I303-M305 PolarHBondContact O-N 2.82Å; I303-A306 PolarHBondContact O-N 3.45Å; I303-T307 PolarHBondContact O-N 3.41Å; I303-T307 PolarHBondContact O-OG1 2.84Å; I303-F432 HydrophobicContact CG1-CE1 3.98Å; I303-F432 HydrophobicContact CG1-CZ 4.19Å; I303-L433 HydrophobicContact CG2-CD1 3.85Å; I303-A436 HydrophobicContact CD1-CB 4.03Å; I303-A436 HydrophobicContact CG1-CB 4.17Å
304	F	90.3	Very high	85.9	Confident	113 Å²	113	79.1 Å²	79.1	50%	0.496	38%	0.378	S	S	.	.	H	α-helix	trans	-59.3	-46.7	177.9	177.7	-107.7	0	0	0	112.6	V300 W301 T307 I308	V300-F304 WeakPolarHBondContact O-CB 3.38Å; V300-F304 PolarHBondContact O-N 2.55Å; W301-F304 HydrophobicContact CE3-CD1 4.47Å; W301-F304 PolarHBondContact O-N 2.91Å; F304-T307 WeakPolarHBondContact O-CB 3.39Å; F304-T307 PolarHBondContact O-N 2.86Å; F304-I308 HydrophobicContact CD1-CD1 3.92Å; F304-I308 HydrophobicContact CE1-CD1 3.32Å; F304-I308 HydrophobicContact CE1-CG1 4.38Å; F304-I308 HydrophobicContact CE2-CD1 4.15Å; F304-I308 HydrophobicContact CZ-CD1 3.47Å; F304-I308 VanDerWaalsContact CZ-CD1 3.47Å; F304-I308 HydrophobicContact CZ-CG1 4.3Å; F304-I308 PolarHBondContact O-N 3.38Å
305	M	85.1	Confident	84.8	Confident	55 Å²	55	75.4 Å²	75.4	27%	0.271	37%	0.366	S	S	.	.	H	α-helix	trans	-64.8	-40.9	177.4	-79.6	-63.8	176.1	0	0	112.7	W301 K302 I303 T307 I308 N309	W301-M305 HydrophobicContact CD2-CE 4.49Å; W301-M305 HydrophobicContact CD2-CG 4.3Å; W301-M305 HydrophobicContact CH2-CE 3.29Å; W301-M305 HydrophobicContact CZ2-CE 3.09Å; W301-M305 HydrophobicContact CZ2-CG 4.24Å; W301-M305 HydrophobicContact CZ2-SD 4.48Å; W301-M305 HydrophobicContact CZ3-CE 4.07Å; W301-M305 WeakPolarHBondContact O-CB 3.46Å; W301-M305 WeakPolarHBondContact O-CG 3.39Å; W301-M305 PolarHBondContact O-N 3.3Å; K302-M305 PolarHBondContact O-N 3.21Å; I303-M305 PolarHBondContact O-N 2.82Å; M305-T307 VanDerWaalsContact C-N 3.3Å; M305-T307 PolarHBondContact O-N 3.34Å; M305-I308 PolarHBondContact O-N 3.01Å; M305-I308 HydrophobicContact SD-CD1 4.46Å; M305-N309 PolarHBondContact O-N 2.86Å; M305-N309 PolarHBondContact O-OD1 3.14Å
306	A	86.4	Confident	83.6	Confident	3 Å²	3	74.4 Å²	74.4	3%	0.025	38%	0.379	C	S	.	.	H	α-helix	trans	-60.6	-41.3	173.7	0	0	0	0	0	111.1	K302 I303 N309 I310 D429 F432	K302-A306 WeakPolarHBondContact O-CB 3.24Å; K302-A306 PolarHBondContact O-N 2.65Å; I303-A306 PolarHBondContact O-N 3.45Å; A306-N309 PolarHBondContact O-N 3.35Å; A306-I310 WeakPolarHBondContact O-CD1 3.18Å; A306-I310 WeakPolarHBondContact O-CG1 3.47Å; A306-I310 PolarHBondContact O-N 3.29Å; A306-I310 VanDerWaalsContact O-N 3.07Å; A306-D429 HydrophobicContact CB-CB 4.2Å; A306-F432 HydrophobicContact CB-CD1 3.98Å; A306-F432 HydrophobicContact CB-CE1 4.27Å
307	T	89.4	Confident	82	Confident	54 Å²	54	82.3 Å²	82.3	33%	0.331	41%	0.409	S	S	.	.	H	α-helix	trans	-60.8	-46	173.9	-54.3	0	0	0	0	111.9	I303 F304 M305 I310 V311	I303-T307 PolarHBondContact O-N 3.41Å; I303-T307 PolarHBondContact O-OG1 2.84Å; F304-T307 WeakPolarHBondContact O-CB 3.39Å; F304-T307 PolarHBondContact O-N 2.86Å; M305-T307 VanDerWaalsContact C-N 3.3Å; M305-T307 PolarHBondContact O-N 3.34Å; T307-I310 PolarHBondContact O-N 2.96Å; T307-V311 HydrophobicContact CG2-CG2 4.27Å; T307-V311 WeakPolarHBondContact O-CB 3.34Å; T307-V311 VanDerWaalsContact O-CG2 3.28Å; T307-V311 WeakPolarHBondContact O-CG2 3.39Å; T307-V311 PolarHBondContact O-N 3.06Å
308	I	87.1	Confident	80.2	Confident	36 Å²	36	79.1 Å²	79.1	19%	0.185	40%	0.396	C	S	.	.	H	α-helix	trans	-60.3	-47.5	176.6	-73.2	178.3	0	0	0	111.2	F304 M305 I310 V311 F312	F304-I308 HydrophobicContact CD1-CD1 3.92Å; F304-I308 HydrophobicContact CE1-CD1 3.32Å; F304-I308 HydrophobicContact CE1-CG1 4.38Å; F304-I308 HydrophobicContact CE2-CD1 4.15Å; F304-I308 HydrophobicContact CZ-CD1 3.47Å; F304-I308 VanDerWaalsContact CZ-CD1 3.47Å; F304-I308 HydrophobicContact CZ-CG1 4.3Å; F304-I308 PolarHBondContact O-N 3.38Å; M305-I308 PolarHBondContact O-N 3.01Å; M305-I308 HydrophobicContact SD-CD1 4.46Å; I308-I310 VanDerWaalsContact C-N 3.26Å; I308-I310 PolarHBondContact O-N 3.33Å; I308-V311 PolarHBondContact O-N 3.38Å; I308-F312 HydrophobicContact CB-CD2 4.39Å; I308-F312 HydrophobicContact CG2-CD2 3.85Å; I308-F312 WeakPolarHBondContact O-CB 3.05Å; I308-F312 WeakPolarHBondContact O-CD2 3.46Å; I308-F312 PolarHBondContact O-N 3.33Å
309	N	85.9	Confident	78.7	Confident	43 Å²	43	74.9 Å²	74.9	23%	0.23	38%	0.381	C	S	.	.	H	α-helix	trans	-58.8	-40.5	-179.3	-69.8	-11.9	0	0	0	111.6	M305 A306 D313 R314 D429	M305-N309 PolarHBondContact O-N 2.86Å; M305-N309 PolarHBondContact O-OD1 3.14Å; A306-N309 PolarHBondContact O-N 3.35Å; N309-D313 VanDerWaalsContact O-CA 3.29Å; N309-D313 WeakPolarHBondContact O-CA 3.46Å; N309-D313 PolarHBondContact O-N 3.46Å; N309-D313 VanDerWaalsContact O-N 3.17Å; N309-R314 PolarHBondContact O-N 2.87Å; N309-R314 VanDerWaalsContact O-N 3.12Å; N309-D429 WeakPolarHBondContact CB-OD2 3.43Å; N309-D429 PolarHBondContact ND2-OD2 3Å
310	I	87.5	Confident	77.2	Confident	43 Å²	43	79.7 Å²	79.7	22%	0.221	41%	0.412	C	S	.	.	H	α-helix	trans	-69.4	-46.4	178.1	-65.6	163.3	0	0	0	111.5	A306 T307 I308 D429 V430 L433	A306-I310 WeakPolarHBondContact O-CD1 3.18Å; A306-I310 WeakPolarHBondContact O-CG1 3.47Å; A306-I310 PolarHBondContact O-N 3.29Å; A306-I310 VanDerWaalsContact O-N 3.07Å; T307-I310 PolarHBondContact O-N 2.96Å; I308-I310 VanDerWaalsContact C-N 3.26Å; I308-I310 PolarHBondContact O-N 3.33Å; I310-D429 HydrophobicContact CD1-CB 4.32Å; I310-D429 HydrophobicContact CG1-CB 4.2Å; I310-V430 HydrophobicContact CD1-CB 4.45Å; I310-V430 HydrophobicContact CD1-CG2 3.91Å; I310-V430 HydrophobicContact CG1-CG2 3.88Å; I310-V430 HydrophobicContact CG2-CG2 4.46Å; I310-L433 HydrophobicContact CD1-CB 4.25Å; I310-L433 HydrophobicContact CD1-CD2 3.77Å
311	V	89.1	Confident	75.5	Confident	103 Å²	103	77.2 Å²	77.2	62%	0.624	40%	0.397	S	S	*	.	H	α-helix	trans	-71	-42.3	-174.7	170.7	0	0	0	0	112	T307 I308	T307-V311 HydrophobicContact CG2-CG2 4.27Å; T307-V311 WeakPolarHBondContact O-CB 3.34Å; T307-V311 VanDerWaalsContact O-CG2 3.28Å; T307-V311 WeakPolarHBondContact O-CG2 3.39Å; T307-V311 PolarHBondContact O-N 3.06Å; I308-V311 PolarHBondContact O-N 3.38Å
312	F	84.9	Confident	74.3	Confident	151 Å²	151	71.3 Å²	71.3	66%	0.662	38%	0.377	S	S	*	.	T	Hydrogen-bonded Turn	trans	-97.9	7.6	-175.3	-65.3	-77.1	0	0	0	113.6	I308 R314	I308-F312 HydrophobicContact CB-CD2 4.39Å; I308-F312 HydrophobicContact CG2-CD2 3.85Å; I308-F312 WeakPolarHBondContact O-CB 3.05Å; I308-F312 WeakPolarHBondContact O-CD2 3.46Å; I308-F312 PolarHBondContact O-N 3.33Å; F312-R314 HydrophobicContact CB-CB 4.49Å; F312-R314 PolarHBondContact O-N 3.46Å; F312-R314 VanDerWaalsContact O-N 3.08Å
313	D	76.8	Confident	73.3	Confident	92 Å²	92	75 Å²	75	49%	0.492	39%	0.39	S	S	.	.	T	Hydrogen-bonded Turn	trans	45.2	39.9	-173.6	-155.6	10.4	0	0	0	112.7	N309 V315 R426	N309-D313 VanDerWaalsContact O-CA 3.29Å; N309-D313 WeakPolarHBondContact O-CA 3.46Å; N309-D313 PolarHBondContact O-N 3.46Å; N309-D313 VanDerWaalsContact O-N 3.17Å; D313-V315 PolarHBondContact O-N 3.38Å; D313-R426 IonicContact OD1-CZ 2.88Å; D313-R426 IonicContact OD1-NE 3.67Å; D313-R426 IonicContact OD1-NH1 3.6Å; D313-R426 PolarHBondContact OD1-NH1 2.95Å; D313-R426 IonicContact OD2-NH1 3.85Å; D313-R426 PolarHBondContact OD2-NH1 3.36Å
314	R	72.6	Confident	72.2	Confident	149 Å²	149	75 Å²	75	56%	0.562	40%	0.397	S	S	*	.			trans	-85.3	102.4	-173.7	-171.4	-179.1	178.6	-176	-0.9	108.9	N309 F312	N309-R314 PolarHBondContact O-N 2.87Å; N309-R314 VanDerWaalsContact O-N 3.12Å; F312-R314 HydrophobicContact CB-CB 4.49Å; F312-R314 PolarHBondContact O-N 3.46Å; F312-R314 VanDerWaalsContact O-N 3.08Å
315	V	62.6	Low	71	Confident	51 Å²	51	70.6 Å²	70.6	31%	0.309	38%	0.379	S	S	.	.			trans	-82.3	120.8	170	-173.5	0	0	0	0	108.5	D313 K317 N422	D313-V315 PolarHBondContact O-N 3.38Å; V315-K317 PolarHBondContact O-N 3.35Å; V315-N422 HydrophobicContact CG1-CB 4.1Å; V315-N422 WeakPolarHBondContact CG1-OD1 3.47Å; V315-N422 HydrophobicContact CG2-CB 4.23Å
316	G	55.9	Low	70.2	Confident	61 Å²	61	71.6 Å²	71.6	63%	0.629	38%	0.383	S	S	*	.			trans	-57.5	103.1	174.5	0	0	0	0	0	110.7	T318	G316-T318 VanDerWaalsContact C-N 3.31Å
317	K	52.4	Low	69.5	Low	200 Å²	200	76.5 Å²	76.5	87%	0.87	41%	0.407	S	S	*	.	S	Bend	trans	-78.6	-15.8	-178.4	-69.5	-174.7	178.9	179.9	0	113.5	V315	V315-K317 PolarHBondContact O-N 3.35Å
318	T	51.3	Low	68.7	Low	59 Å²	59	77.6 Å²	77.6	36%	0.362	41%	0.414	S	S	.	.	S	Bend	trans	-138.8	136.6	-179.5	52.2	0	0	0	0	108.3	G316 R323	G316-T318 VanDerWaalsContact C-N 3.31Å; T318-R323 WeakPolarHBondContact OG1-CD 3.04Å
319	D	54.6	Low	68	Low	25 Å²	25	77.3 Å²	77.3	13%	0.134	41%	0.414	C	S	.	.			trans	-58.4	141	177.9	57.6	-62.2	0	0	0	110.9	V321 T322 R323	D319-V321 PolarHBondContact O-N 3.09Å; D319-V321 VanDerWaalsContact O-N 3.09Å; D319-T322 PolarHBondContact O-N 2.81Å; D319-T322 WeakPolarHBondContact OD1-CB 3.43Å; D319-T322 PolarHBondContact OD1-OG1 2.83Å; D319-T322 WeakPolarHBondContact OD2-CA 3.43Å; D319-T322 WeakPolarHBondContact OD2-CB 3.44Å; D319-T322 PolarHBondContact OD2-N 3.23Å; D319-T322 PolarHBondContact OD2-OG1 3.25Å; D319-R323 WeakPolarHBondContact O-CB 3.26Å; D319-R323 PolarHBondContact O-N 3.31Å
320	P	55.9	Low	67.3	Low	113 Å²	113	81.6 Å²	81.6	73%	0.734	44%	0.437	S	S	*	.	H	α-helix	trans	-57.6	-29.2	-175.3	-23.8	32.2	0	0	0	113.2	G324	P320-G324 PolarHBondContact O-N 3.36Å
321	V	55.7	Low	66.9	Low	46 Å²	46	89.3 Å²	89.3	28%	0.279	46%	0.464	S	S	.	.	H	α-helix	trans	-77.3	-48.9	-177.8	179.6	0	0	0	0	110.9	D319 R323 G324 I325 I345 L349	D319-V321 PolarHBondContact O-N 3.09Å; D319-V321 VanDerWaalsContact O-N 3.09Å; V321-R323 VanDerWaalsContact C-N 3.32Å; V321-R323 PolarHBondContact O-N 3.04Å; V321-G324 WeakPolarHBondContact O-CA 3.35Å; V321-G324 PolarHBondContact O-N 3.12Å; V321-G324 VanDerWaalsContact O-N 3.11Å; V321-I325 HydrophobicContact CG1-CD1 4.04Å; V321-I325 WeakPolarHBondContact O-CG1 3.24Å; V321-I325 PolarHBondContact O-N 3.42Å; V321-I345 HydrophobicContact CG1-CG2 3.84Å; V321-L349 HydrophobicContact CB-CD2 4.25Å; V321-L349 HydrophobicContact CG2-CD2 3.6Å
322	T	61.3	Low	66.3	Low	23 Å²	23	89.3 Å²	89.3	14%	0.141	46%	0.46	C	S	.	.	H	α-helix	trans	-61.9	-40.5	174.1	-61.2	0	0	0	0	111.4	D319 G324 I325 E326	D319-T322 PolarHBondContact O-N 2.81Å; D319-T322 WeakPolarHBondContact OD1-CB 3.43Å; D319-T322 PolarHBondContact OD1-OG1 2.83Å; D319-T322 WeakPolarHBondContact OD2-CA 3.43Å; D319-T322 WeakPolarHBondContact OD2-CB 3.44Å; D319-T322 PolarHBondContact OD2-N 3.23Å; D319-T322 PolarHBondContact OD2-OG1 3.25Å; T322-G324 VanDerWaalsContact C-N 3.3Å; T322-G324 PolarHBondContact O-N 2.81Å; T322-I325 PolarHBondContact O-N 2.99Å; T322-E326 HydrophobicContact CG2-CG 4.4Å; T322-E326 WeakPolarHBondContact O-CB 3.38Å; T322-E326 WeakPolarHBondContact O-CG 3.35Å; T322-E326 PolarHBondContact O-N 2.95Å
323	R	65.4	Low	65.3	Low	124 Å²	124	85.3 Å²	85.3	47%	0.468	46%	0.462	S	S	.	.	H	α-helix	trans	-60.5	-41	173.5	-166	110.4	179.1	144.8	0.9	111.9	T318 D319 V321 I327	T318-R323 WeakPolarHBondContact OG1-CD 3.04Å; D319-R323 WeakPolarHBondContact O-CB 3.26Å; D319-R323 PolarHBondContact O-N 3.31Å; V321-R323 VanDerWaalsContact C-N 3.32Å; V321-R323 PolarHBondContact O-N 3.04Å; R323-I327 HydrophobicContact CG-CD1 4.17Å; R323-I327 WeakPolarHBondContact O-CD1 3.44Å; R323-I327 VanDerWaalsContact O-CG1 3.23Å; R323-I327 WeakPolarHBondContact O-CG1 3.21Å; R323-I327 PolarHBondContact O-N 3.02Å
324	G	66.5	Low	65	Low	30 Å²	30	85.6 Å²	85.6	31%	0.309	46%	0.463	S	S	.	.	H	α-helix	trans	-64	-42	175.4	0	0	0	0	0	112.5	P320 V321 T322 T328	P320-G324 PolarHBondContact O-N 3.36Å; V321-G324 WeakPolarHBondContact O-CA 3.35Å; V321-G324 PolarHBondContact O-N 3.12Å; V321-G324 VanDerWaalsContact O-N 3.11Å; T322-G324 VanDerWaalsContact C-N 3.3Å; T322-G324 PolarHBondContact O-N 2.81Å; G324-T328 WeakPolarHBondContact O-CB 3.45Å; G324-T328 PolarHBondContact O-N 3.45Å; G324-T328 PolarHBondContact O-OG1 3.01Å
325	I	65.5	Low	64.4	Low	22 Å²	22	88.2 Å²	88.2	11%	0.113	48%	0.481	C	S	.	.	H	α-helix	trans	-64.4	-47.2	175.6	-66.2	165.9	0	0	0	110.2	V321 T322 I327 T328 V329 V338 I345	V321-I325 HydrophobicContact CG1-CD1 4.04Å; V321-I325 WeakPolarHBondContact O-CG1 3.24Å; V321-I325 PolarHBondContact O-N 3.42Å; T322-I325 PolarHBondContact O-N 2.99Å; I325-I327 VanDerWaalsContact C-N 3.35Å; I325-I327 PolarHBondContact O-N 3.36Å; I325-T328 PolarHBondContact O-N 3.21Å; I325-T328 VanDerWaalsContact O-N 3.13Å; I325-V329 HydrophobicContact CG2-CG2 4.02Å; I325-V329 WeakPolarHBondContact O-CB 3.25Å; I325-V329 VanDerWaalsContact O-CG2 3.23Å; I325-V329 WeakPolarHBondContact O-CG2 3.5Å; I325-V329 PolarHBondContact O-N 3.01Å; I325-V338 HydrophobicContact CG2-CG1 4.25Å; I325-I345 HydrophobicContact CD1-CD1 3.88Å; I325-I345 HydrophobicContact CD1-CG2 4.29Å
326	E	67.2	Low	64.5	Low	76 Å²	76	89.3 Å²	89.3	36%	0.355	48%	0.482	S	S	.	.	H	α-helix	trans	-56.5	-45.9	177	-77.2	175.7	179.8	0	0	112.2	T322 T328 N330	T322-E326 HydrophobicContact CG2-CG 4.4Å; T322-E326 WeakPolarHBondContact O-CB 3.38Å; T322-E326 WeakPolarHBondContact O-CG 3.35Å; T322-E326 PolarHBondContact O-N 2.95Å; E326-T328 VanDerWaalsContact C-N 3.34Å; E326-N330 VanDerWaalsContact O-CB 3.29Å; E326-N330 WeakPolarHBondContact O-CB 3.26Å; E326-N330 PolarHBondContact O-N 2.85Å; E326-N330 PolarHBondContact O-ND2 3.32Å
327	I	72.8	Confident	65.2	Low	106 Å²	106	90.9 Å²	90.9	54%	0.544	48%	0.476	S	S	.	.	H	α-helix	trans	-63.9	-42.7	177.3	-67.8	164.5	0	0	0	110.4	R323 I325 Y331	R323-I327 HydrophobicContact CG-CD1 4.17Å; R323-I327 WeakPolarHBondContact O-CD1 3.44Å; R323-I327 VanDerWaalsContact O-CG1 3.23Å; R323-I327 WeakPolarHBondContact O-CG1 3.21Å; R323-I327 PolarHBondContact O-N 3.02Å; I325-I327 VanDerWaalsContact C-N 3.35Å; I325-I327 PolarHBondContact O-N 3.36Å; I327-Y331 WeakPolarHBondContact O-CB 3.3Å; I327-Y331 PolarHBondContact O-N 3.47Å
328	T	70.9	Confident	65.9	Low	77 Å²	77	83.7 Å²	83.7	47%	0.472	45%	0.448	S	S	.	.	H	α-helix	trans	-66.9	-42.3	-178.7	-56.6	0	0	0	0	111.7	G324 I325 E326 Y331 L332	G324-T328 WeakPolarHBondContact O-CB 3.45Å; G324-T328 PolarHBondContact O-N 3.45Å; G324-T328 PolarHBondContact O-OG1 3.01Å; I325-T328 PolarHBondContact O-N 3.21Å; I325-T328 VanDerWaalsContact O-N 3.13Å; E326-T328 VanDerWaalsContact C-N 3.34Å; T328-Y331 PolarHBondContact O-N 3.04Å; T328-L332 HydrophobicContact CG2-CD1 3.68Å; T328-L332 WeakPolarHBondContact O-CB 3.23Å; T328-L332 WeakPolarHBondContact O-CG 3.4Å; T328-L332 PolarHBondContact O-N 3.21Å
329	V	72.3	Confident	66.7	Low	29 Å²	29	88 Å²	88	18%	0.176	46%	0.462	C	S	.	.	H	α-helix	trans	-66.5	-44.5	177.8	171.3	0	0	0	0	110.8	I325 Y331 G333 F336 V338	I325-V329 HydrophobicContact CG2-CG2 4.02Å; I325-V329 WeakPolarHBondContact O-CB 3.25Å; I325-V329 VanDerWaalsContact O-CG2 3.23Å; I325-V329 WeakPolarHBondContact O-CG2 3.5Å; I325-V329 PolarHBondContact O-N 3.01Å; V329-Y331 VanDerWaalsContact C-N 3.34Å; V329-Y331 PolarHBondContact O-N 3.35Å; V329-G333 PolarHBondContact O-N 3.02Å; V329-G333 VanDerWaalsContact O-N 3.09Å; V329-F336 HydrophobicContact CG1-CB 4.46Å; V329-F336 HydrophobicContact CG2-CB 4.02Å; V329-F336 HydrophobicContact CG2-CD1 4.06Å; V329-F336 HydrophobicContact CG2-CG 4.38Å; V329-V338 HydrophobicContact CG1-CG2 4.15Å; V329-V338 HydrophobicContact CG2-CG2 4.17Å
330	N	72.8	Confident	67.6	Low	134 Å²	134	91.7 Å²	91.7	72%	0.717	48%	0.477	S	S	*	.	H	α-helix	trans	-67.2	-33.6	176.9	-72.6	-25.7	0	0	0	112.8	E326	E326-N330 VanDerWaalsContact O-CB 3.29Å; E326-N330 WeakPolarHBondContact O-CB 3.26Å; E326-N330 PolarHBondContact O-N 2.85Å; E326-N330 PolarHBondContact O-ND2 3.32Å
331	Y	78.2	Confident	68.6	Low	204 Å²	204	92.1 Å²	92.1	80%	0.8	46%	0.464	S	S	*	.	H	α-helix	trans	-76.5	-36.5	179.1	-172.6	-99.8	0	0	0	112.9	I327 T328 V329	I327-Y331 WeakPolarHBondContact O-CB 3.3Å; I327-Y331 PolarHBondContact O-N 3.47Å; T328-Y331 PolarHBondContact O-N 3.04Å; V329-Y331 VanDerWaalsContact C-N 3.34Å; V329-Y331 PolarHBondContact O-N 3.35Å
332	L	76.3	Confident	69.2	Low	103 Å²	103	90.9 Å²	90.9	54%	0.539	46%	0.458	S	S	.	.	H	α-helix	trans	-89.4	-11.1	-177.4	-69.4	169.9	0	0	0	114	T328 I334	T328-L332 HydrophobicContact CG2-CD1 3.68Å; T328-L332 WeakPolarHBondContact O-CB 3.23Å; T328-L332 WeakPolarHBondContact O-CG 3.4Å; T328-L332 PolarHBondContact O-N 3.21Å; L332-I334 HydrophobicContact CB-CD1 3.87Å; L332-I334 HydrophobicContact CB-CG1 3.99Å; L332-I334 HydrophobicContact CD1-CD1 4.3Å; L332-I334 PolarHBondContact O-N 3.43Å; L332-I334 VanDerWaalsContact O-N 3.08Å
333	G	63.7	Low	69.7	Low	68 Å²	68	92.6 Å²	92.6	70%	0.701	46%	0.464	S	S	*	.	T	Hydrogen-bonded Turn	trans	62.9	15.5	177.6	0	0	0	0	0	114.4	V329	V329-G333 PolarHBondContact O-N 3.02Å; V329-G333 VanDerWaalsContact O-N 3.09Å
334	I	70.6	Confident	70.3	Confident	98 Å²	98	90.3 Å²	90.3	50%	0.503	46%	0.459	S	S	.	.			trans	-81.2	130.5	-179.2	-60.8	170.3	0	0	0	107.9	L332 F336	L332-I334 HydrophobicContact CB-CD1 3.87Å; L332-I334 HydrophobicContact CB-CG1 3.99Å; L332-I334 HydrophobicContact CD1-CD1 4.3Å; L332-I334 PolarHBondContact O-N 3.43Å; L332-I334 VanDerWaalsContact O-N 3.08Å; I334-F336 HydrophobicContact CG2-CB 4.23Å; I334-F336 PolarHBondContact O-N 3.46Å
335	Q	61.6	Low	70.8	Confident	204 Å²	204	91.6 Å²	91.6	95%	0.953	46%	0.458	S	S	*	.			trans	-70	72.8	166.7	-66.9	-159.3	-4.9	0	0	109.5
336	F	63.8	Low	71	Confident	74 Å²	74	90.8 Å²	90.8	33%	0.325	45%	0.454	S	S	.	.			trans	-86.5	127.6	178.2	-165	-109	0	0	0	107.8	V329 I334 V338 W341	V329-F336 HydrophobicContact CG1-CB 4.46Å; V329-F336 HydrophobicContact CG2-CB 4.02Å; V329-F336 HydrophobicContact CG2-CD1 4.06Å; V329-F336 HydrophobicContact CG2-CG 4.38Å; I334-F336 HydrophobicContact CG2-CB 4.23Å; I334-F336 PolarHBondContact O-N 3.46Å; F336-V338 WeakPolarHBondContact O-CG2 3.43Å; F336-V338 PolarHBondContact O-N 2.94Å; F336-W341 HydrophobicContact CD1-CB 4.21Å; F336-W341 HydrophobicContact CD1-CG 4.35Å; F336-W341 HydrophobicContact CE1-CB 3.21Å; F336-W341 AromaticContact CE1-CD1 3.56Å; F336-W341 HydrophobicContact CE1-CD2 4.25Å; F336-W341 AromaticContact CE1-CG 3.39Å; F336-W341 HydrophobicContact CE1-CG 3.39Å; F336-W341 AromaticContact CE2-CD1 3.54Å; F336-W341 HydrophobicContact CE2-CD2 4.11Å; F336-W341 AromaticContact CE2-CE2 3.97Å; F336-W341 AromaticContact CE2-CG 3.85Å; F336-W341 HydrophobicContact CE2-CG 3.85Å; F336-W341 AromaticContact CE2-NE1 3.6Å; F336-W341 HydrophobicContact CZ-CB 3.45Å; F336-W341 VanDerWaalsContact CZ-CB 3.45Å; F336-W341 AromaticContact CZ-CD1 3.22Å; F336-W341 AromaticContact CZ-CD2 3.49Å; F336-W341 HydrophobicContact CZ-CD2 3.49Å; F336-W341 VanDerWaalsContact CZ-CD2 3.49Å; F336-W341 AromaticContact CZ-CE2 3.86Å; F336-W341 HydrophobicContact CZ-CE3 4.26Å; F336-W341 AromaticContact CZ-CG 3.08Å; F336-W341 HydrophobicContact CZ-CG 3.08Å; F336-W341 AromaticContact CZ-NE1 3.67Å
337	D	70.3	Confident	71.6	Confident	94 Å²	94	90 Å²	90	50%	0.503	45%	0.45	S	S	.	.			trans	-69.7	87.2	172	-173.5	-5.5	0	0	0	108.9	K339 F340 W341	D337-K339 PolarHBondContact O-N 3.31Å; D337-K339 PolarHBondContact OD1-N 3.46Å; D337-K339 VanDerWaalsContact OD1-N 3.16Å; D337-F340 HydrophobicContact CB-CB 4.17Å; D337-F340 PolarHBondContact O-N 3.03Å; D337-F340 PolarHBondContact OD1-N 2.86Å; D337-F340 WeakPolarHBondContact OD2-CB 3.39Å; D337-W341 PolarHBondContact O-N 2.89Å; D337-W341 VanDerWaalsContact O-N 3.14Å
338	V	67.9	Low	72	Confident	48 Å²	48	89.8 Å²	89.8	29%	0.291	45%	0.449	S	S	.	.	H	α-helix	trans	-56.6	-33.4	-178.4	-175.5	0	0	0	0	110.3	I325 V329 F336 S342	I325-V338 HydrophobicContact CG2-CG1 4.25Å; V329-V338 HydrophobicContact CG1-CG2 4.15Å; V329-V338 HydrophobicContact CG2-CG2 4.17Å; F336-V338 WeakPolarHBondContact O-CG2 3.43Å; F336-V338 PolarHBondContact O-N 2.94Å; V338-S342 WeakPolarHBondContact O-CA 3.5Å; V338-S342 WeakPolarHBondContact O-CB 3.27Å; V338-S342 PolarHBondContact O-N 3.31Å; V338-S342 PolarHBondContact O-OG 3.15Å
339	K	67.8	Low	72.3	Confident	149 Å²	149	88.8 Å²	88.8	65%	0.648	44%	0.44	S	S	*	.	H	α-helix	trans	-70.8	-49.6	-178.3	-69	-172	176.1	-169.1	0	111.6	D337 S342 Q343	D337-K339 PolarHBondContact O-N 3.31Å; D337-K339 PolarHBondContact OD1-N 3.46Å; D337-K339 VanDerWaalsContact OD1-N 3.16Å; K339-S342 PolarHBondContact O-OG 2.81Å; K339-S342 VanDerWaalsContact O-OG 3.07Å; K339-Q343 PolarHBondContact O-N 3.42Å
340	F	74.1	Confident	72.5	Confident	104 Å²	104	87.5 Å²	87.5	46%	0.456	43%	0.432	S	S	.	.	H	α-helix	trans	-60.6	-49	178.3	179.4	-98	0	0	0	112.3	D337 H344	D337-F340 HydrophobicContact CB-CB 4.17Å; D337-F340 PolarHBondContact O-N 3.03Å; D337-F340 PolarHBondContact OD1-N 2.86Å; D337-F340 WeakPolarHBondContact OD2-CB 3.39Å; F340-H344 AromaticContact CD2-NE2 3.99Å; F340-H344 AromaticContact CE1-CD2 3.62Å; F340-H344 AromaticContact CE1-NE2 3.77Å; F340-H344 AromaticContact CE2-CD2 3.95Å; F340-H344 AromaticContact CE2-NE2 3.33Å; F340-H344 VanDerWaalsContact CE2-NE2 3.33Å; F340-H344 WeakPolarHBondContact CE2-NE2 3.49Å; F340-H344 AromaticContact CZ-CD2 3.59Å; F340-H344 AromaticContact CZ-NE2 3.2Å; F340-H344 WeakPolarHBondContact CZ-NE2 3.18Å; F340-H344 PolarHBondContact O-CD2 3.35Å
341	W	75.6	Confident	73	Confident	121 Å²	121	82 Å²	82	46%	0.458	41%	0.408	S	S	.	.	H	α-helix	trans	-77.2	-32.7	-175.6	-77.7	100.1	0	0	0	113.8	F336 D337 Q343 H344 I345	F336-W341 HydrophobicContact CD1-CB 4.21Å; F336-W341 HydrophobicContact CD1-CG 4.35Å; F336-W341 HydrophobicContact CE1-CB 3.21Å; F336-W341 AromaticContact CE1-CD1 3.56Å; F336-W341 HydrophobicContact CE1-CD2 4.25Å; F336-W341 AromaticContact CE1-CG 3.39Å; F336-W341 HydrophobicContact CE1-CG 3.39Å; F336-W341 AromaticContact CE2-CD1 3.54Å; F336-W341 HydrophobicContact CE2-CD2 4.11Å; F336-W341 AromaticContact CE2-CE2 3.97Å; F336-W341 AromaticContact CE2-CG 3.85Å; F336-W341 HydrophobicContact CE2-CG 3.85Å; F336-W341 AromaticContact CE2-NE1 3.6Å; F336-W341 HydrophobicContact CZ-CB 3.45Å; F336-W341 VanDerWaalsContact CZ-CB 3.45Å; F336-W341 AromaticContact CZ-CD1 3.22Å; F336-W341 AromaticContact CZ-CD2 3.49Å; F336-W341 HydrophobicContact CZ-CD2 3.49Å; F336-W341 VanDerWaalsContact CZ-CD2 3.49Å; F336-W341 AromaticContact CZ-CE2 3.86Å; F336-W341 HydrophobicContact CZ-CE3 4.26Å; F336-W341 AromaticContact CZ-CG 3.08Å; F336-W341 HydrophobicContact CZ-CG 3.08Å; F336-W341 AromaticContact CZ-NE1 3.67Å; D337-W341 PolarHBondContact O-N 2.89Å; D337-W341 VanDerWaalsContact O-N 3.14Å; W341-Q343 VanDerWaalsContact C-N 3.29Å; W341-Q343 PolarHBondContact O-N 3.42Å; W341-H344 PolarHBondContact O-N 3.21Å; W341-I345 HydrophobicContact CB-CD1 4.49Å; W341-I345 WeakPolarHBondContact O-CB 3.15Å; W341-I345 WeakPolarHBondContact O-CD1 3.48Å; W341-I345 WeakPolarHBondContact O-CG1 3.16Å; W341-I345 PolarHBondContact O-N 3.33Å
342	S	68.9	Low	73.1	Confident	21 Å²	21	76.8 Å²	76.8	15%	0.147	39%	0.392	C	S	.	.	H	α-helix	trans	-61.1	-40.2	174.4	60.3	0	0	0	0	111.2	V338 K339 H344 I345 S346	V338-S342 WeakPolarHBondContact O-CA 3.5Å; V338-S342 WeakPolarHBondContact O-CB 3.27Å; V338-S342 PolarHBondContact O-N 3.31Å; V338-S342 PolarHBondContact O-OG 3.15Å; K339-S342 PolarHBondContact O-OG 2.81Å; K339-S342 VanDerWaalsContact O-OG 3.07Å; S342-H344 PolarHBondContact O-N 2.86Å; S342-I345 PolarHBondContact O-N 3.42Å; S342-S346 WeakPolarHBondContact O-CB 3.4Å; S342-S346 PolarHBondContact O-N 3.48Å; S342-S346 PolarHBondContact O-OG 3.36Å
343	Q	71.2	Confident	73.3	Confident	58 Å²	58	74.4 Å²	74.4	27%	0.271	38%	0.38	S	S	.	.	H	α-helix	trans	-58.8	-50.9	176.3	-177.3	-179.9	0.5	0	0	112	I62 K339 W341 S346 F347 Y408	I62-Q343 PolarHBondContact O-NE2 3.04Å; K339-Q343 PolarHBondContact O-N 3.42Å; W341-Q343 VanDerWaalsContact C-N 3.29Å; W341-Q343 PolarHBondContact O-N 3.42Å; Q343-S346 PolarHBondContact O-N 3.24Å; Q343-F347 WeakPolarHBondContact O-CB 3.25Å; Q343-F347 PolarHBondContact O-N 3.29Å; Q343-Y408 HydrophobicContact CB-CE2 4.5Å; Q343-Y408 HydrophobicContact CG-CE2 4.16Å; Q343-Y408 VanDerWaalsContact CG-OH 3.25Å; Q343-Y408 WeakPolarHBondContact CG-OH 3.42Å; Q343-Y408 PolarHBondContact NE2-OH 3.04Å; Q343-Y408 PolarHBondContact OE1-OH 3.19Å; Q343-Y408 VanDerWaalsContact OE1-OH 3.06Å
344	H	79.2	Confident	74.2	Confident	76 Å²	76	71.6 Å²	71.6	35%	0.352	35%	0.349	S	S	.	.	H	α-helix	trans	-66.2	-40.8	-179.3	-69.3	-58.2	0	0	0	112.5	F340 W341 S342 F347 I348	F340-H344 AromaticContact CD2-NE2 3.99Å; F340-H344 AromaticContact CE1-CD2 3.62Å; F340-H344 AromaticContact CE1-NE2 3.77Å; F340-H344 AromaticContact CE2-CD2 3.95Å; F340-H344 AromaticContact CE2-NE2 3.33Å; F340-H344 VanDerWaalsContact CE2-NE2 3.33Å; F340-H344 WeakPolarHBondContact CE2-NE2 3.49Å; F340-H344 AromaticContact CZ-CD2 3.59Å; F340-H344 AromaticContact CZ-NE2 3.2Å; F340-H344 WeakPolarHBondContact CZ-NE2 3.18Å; F340-H344 PolarHBondContact O-CD2 3.35Å; W341-H344 PolarHBondContact O-N 3.21Å; S342-H344 PolarHBondContact O-N 2.86Å; H344-F347 PolarHBondContact O-N 3.38Å; H344-I348 VanDerWaalsContact O-CG1 3.28Å; H344-I348 WeakPolarHBondContact O-CG1 3.38Å; H344-I348 PolarHBondContact O-N 3Å
345	I	75.5	Confident	74.9	Confident	57 Å²	57	71.5 Å²	71.5	29%	0.292	35%	0.353	S	S	.	.	H	α-helix	trans	-66.3	-45.5	177.7	-67.5	168.1	0	0	0	110.4	V321 I325 W341 S342 F347 I348 L349	V321-I345 HydrophobicContact CG1-CG2 3.84Å; I325-I345 HydrophobicContact CD1-CD1 3.88Å; I325-I345 HydrophobicContact CD1-CG2 4.29Å; W341-I345 HydrophobicContact CB-CD1 4.49Å; W341-I345 WeakPolarHBondContact O-CB 3.15Å; W341-I345 WeakPolarHBondContact O-CD1 3.48Å; W341-I345 WeakPolarHBondContact O-CG1 3.16Å; W341-I345 PolarHBondContact O-N 3.33Å; S342-I345 PolarHBondContact O-N 3.42Å; I345-F347 VanDerWaalsContact C-N 3.32Å; I345-F347 PolarHBondContact O-N 3.29Å; I345-I348 PolarHBondContact O-N 3.26Å; I345-L349 WeakPolarHBondContact O-CB 3.33Å; I345-L349 PolarHBondContact O-N 2.9Å
346	S	71.2	Confident	75.8	Confident	5 Å²	5	65.8 Å²	65.8	4%	0.035	33%	0.332	C	S	.	.	H	α-helix	trans	-60.9	-40.5	175.1	-68.3	0	0	0	0	111.5	S342 Q343 L349 V350	S342-S346 WeakPolarHBondContact O-CB 3.4Å; S342-S346 PolarHBondContact O-N 3.48Å; S342-S346 PolarHBondContact O-OG 3.36Å; Q343-S346 PolarHBondContact O-N 3.24Å; S346-L349 PolarHBondContact O-N 3.02Å; S346-V350 VanDerWaalsContact O-CB 3.3Å; S346-V350 WeakPolarHBondContact O-CB 3.36Å; S346-V350 WeakPolarHBondContact O-CG2 3.18Å; S346-V350 PolarHBondContact O-N 3.04Å
347	F	78.9	Confident	76.7	Confident	61 Å²	61	62.9 Å²	62.9	27%	0.268	32%	0.32	S	S	.	.	H	α-helix	trans	-60.3	-51.6	175.1	174.1	-105.4	0	0	0	112.2	I59 I62 L63 Q343 H344 I345 L349 V350 G351	I59-F347 HydrophobicContact CG2-CE2 4Å; I62-F347 HydrophobicContact CB-CD2 4.34Å; I62-F347 HydrophobicContact CG2-CB 3.89Å; I62-F347 HydrophobicContact CG2-CD2 3.85Å; I62-F347 HydrophobicContact CG2-CG 4.32Å; L63-F347 HydrophobicContact CD1-CE2 3.79Å; L63-F347 HydrophobicContact CD1-CZ 3.97Å; L63-F347 HydrophobicContact CD2-CD2 3.89Å; L63-F347 HydrophobicContact CD2-CE1 4.39Å; L63-F347 HydrophobicContact CD2-CE2 3.67Å; L63-F347 HydrophobicContact CD2-CG 4.34Å; L63-F347 HydrophobicContact CD2-CZ 3.94Å; L63-F347 HydrophobicContact CG-CD2 4.1Å; L63-F347 HydrophobicContact CG-CE2 3.64Å; L63-F347 HydrophobicContact CG-CZ 4.18Å; Q343-F347 WeakPolarHBondContact O-CB 3.25Å; Q343-F347 PolarHBondContact O-N 3.29Å; H344-F347 PolarHBondContact O-N 3.38Å; I345-F347 VanDerWaalsContact C-N 3.32Å; I345-F347 PolarHBondContact O-N 3.29Å; F347-L349 VanDerWaalsContact C-N 3.32Å; F347-L349 PolarHBondContact O-N 3.47Å; F347-V350 PolarHBondContact O-N 2.9Å; F347-G351 PolarHBondContact O-N 2.89Å
348	I	81.6	Confident	77.4	Confident	100 Å²	100	59.9 Å²	59.9	51%	0.513	30%	0.304	S	S	.	.	H	α-helix	trans	-61.3	-44.4	179.2	-66.1	171	0	0	0	110.1	H344 I345 G351 I352	H344-I348 VanDerWaalsContact O-CG1 3.28Å; H344-I348 WeakPolarHBondContact O-CG1 3.38Å; H344-I348 PolarHBondContact O-N 3Å; I345-I348 PolarHBondContact O-N 3.26Å; I348-G351 PolarHBondContact O-N 3.33Å; I348-I352 HydrophobicContact CG2-CD1 3.84Å; I348-I352 HydrophobicContact CG2-CG1 4.48Å; I348-I352 VanDerWaalsContact O-CG1 3.3Å; I348-I352 WeakPolarHBondContact O-CG1 3.44Å; I348-I352 PolarHBondContact O-N 2.93Å
349	L	77.1	Confident	78.3	Confident	57 Å²	57	65.8 Å²	65.8	30%	0.298	32%	0.321	S	S	.	.	H	α-helix	trans	-62.3	-49.5	179.4	-176.4	75	0	0	0	111.6	V321 I345 S346 F347 G351 I352 I353	V321-L349 HydrophobicContact CB-CD2 4.25Å; V321-L349 HydrophobicContact CG2-CD2 3.6Å; I345-L349 WeakPolarHBondContact O-CB 3.33Å; I345-L349 PolarHBondContact O-N 2.9Å; S346-L349 PolarHBondContact O-N 3.02Å; F347-L349 VanDerWaalsContact C-N 3.32Å; F347-L349 PolarHBondContact O-N 3.47Å; L349-G351 VanDerWaalsContact C-N 3.3Å; L349-G351 PolarHBondContact O-N 3.44Å; L349-I352 PolarHBondContact O-N 3.08Å; L349-I353 HydrophobicContact CD2-CD1 4.42Å; L349-I353 HydrophobicContact CG-CD1 3.94Å; L349-I353 VanDerWaalsContact O-CG1 3.26Å; L349-I353 WeakPolarHBondContact O-CG1 3.43Å; L349-I353 PolarHBondContact O-N 2.6Å
350	V	76.7	Confident	79	Confident	1 Å²	1	60.4 Å²	60.4	1%	0.006	31%	0.308	C	S	.	.	H	α-helix	trans	-60.4	-43	177.4	169.7	0	0	0	0	110.1	I58 I62 S346 F347 I352 I353 I354 I400 M404	I58-V350 HydrophobicContact CG2-CG1 3.93Å; I62-V350 HydrophobicContact CD1-CB 4.15Å; I62-V350 HydrophobicContact CD1-CG1 3.96Å; I62-V350 HydrophobicContact CD1-CG2 4.26Å; S346-V350 VanDerWaalsContact O-CB 3.3Å; S346-V350 WeakPolarHBondContact O-CB 3.36Å; S346-V350 WeakPolarHBondContact O-CG2 3.18Å; S346-V350 PolarHBondContact O-N 3.04Å; F347-V350 PolarHBondContact O-N 2.9Å; V350-I352 PolarHBondContact O-N 2.89Å; V350-I353 PolarHBondContact O-N 3.37Å; V350-I354 HydrophobicContact CG1-CD1 3.62Å; V350-I354 HydrophobicContact CG1-CG1 4.3Å; V350-I354 WeakPolarHBondContact O-CB 3.27Å; V350-I354 WeakPolarHBondContact O-CG1 3.29Å; V350-I354 PolarHBondContact O-N 3.39Å; V350-I400 HydrophobicContact CG1-CG2 4.18Å; V350-I400 HydrophobicContact CG2-CG2 4.36Å; V350-M404 HydrophobicContact CG2-CG 4.14Å
351	G	82.2	Confident	79.4	Confident	20 Å²	20	55.7 Å²	55.7	21%	0.206	29%	0.287	C	S	.	.	H	α-helix	trans	-58.5	-45.5	174.1	0	0	0	0	0	113.1	F347 I348 L349 I354 V355	F347-G351 PolarHBondContact O-N 2.89Å; I348-G351 PolarHBondContact O-N 3.33Å; L349-G351 VanDerWaalsContact C-N 3.3Å; L349-G351 PolarHBondContact O-N 3.44Å; G351-I354 PolarHBondContact O-N 3.5Å; G351-V355 WeakPolarHBondContact O-CG2 3.4Å; G351-V355 PolarHBondContact O-N 2.87Å
352	I	81.2	Confident	79.9	Confident	93 Å²	93	50.6 Å²	50.6	48%	0.477	27%	0.269	S	S	.	.	H	α-helix	trans	-62	-45.2	175.2	-69.7	167.9	0	0	0	110.6	I348 L349 V350 I354 V355 T356	I348-I352 HydrophobicContact CG2-CD1 3.84Å; I348-I352 HydrophobicContact CG2-CG1 4.48Å; I348-I352 VanDerWaalsContact O-CG1 3.3Å; I348-I352 WeakPolarHBondContact O-CG1 3.44Å; I348-I352 PolarHBondContact O-N 2.93Å; L349-I352 PolarHBondContact O-N 3.08Å; V350-I352 PolarHBondContact O-N 2.89Å; I352-I354 VanDerWaalsContact C-N 3.34Å; I352-I354 PolarHBondContact O-N 3.27Å; I352-V355 PolarHBondContact O-N 3.32Å; I352-T356 HydrophobicContact CG2-CG2 4.07Å; I352-T356 VanDerWaalsContact O-CB 3.28Å; I352-T356 WeakPolarHBondContact O-CB 3.21Å; I352-T356 VanDerWaalsContact O-CG2 3.24Å; I352-T356 WeakPolarHBondContact O-CG2 3.29Å; I352-T356 PolarHBondContact O-N 2.88Å; I352-T356 PolarHBondContact O-OG1 2.96Å
353	I	80.8	Confident	80.7	Confident	54 Å²	54	52.9 Å²	52.9	28%	0.277	28%	0.279	S	S	.	.	H	α-helix	trans	-60	-44.3	177.9	-68.9	166.2	0	0	0	110.7	L349 V350 T356 S357 I400	L349-I353 HydrophobicContact CD2-CD1 4.42Å; L349-I353 HydrophobicContact CG-CD1 3.94Å; L349-I353 VanDerWaalsContact O-CG1 3.26Å; L349-I353 WeakPolarHBondContact O-CG1 3.43Å; L349-I353 PolarHBondContact O-N 2.6Å; V350-I353 PolarHBondContact O-N 3.37Å; I353-T356 PolarHBondContact O-OG1 3.33Å; I353-S357 WeakPolarHBondContact O-CB 3.28Å; I353-S357 PolarHBondContact O-N 3.35Å; I353-S357 PolarHBondContact O-OG 2.96Å; I353-I400 HydrophobicContact CG2-CD1 3.97Å; I353-I400 HydrophobicContact CG2-CG1 4.09Å
354	I	82	Confident	81.3	Confident	8 Å²	8	53 Å²	53	4%	0.041	28%	0.283	C	S	.	.	H	α-helix	trans	-62.6	-53	178	-68.9	165.3	0	0	0	110.6	F55 I59 V350 G351 I352 T356 S357 I358 I400	F55-I354 HydrophobicContact CB-CD1 3.99Å; F55-I354 HydrophobicContact CB-CG1 4.17Å; F55-I354 HydrophobicContact CB-CG2 3.64Å; F55-I354 HydrophobicContact CD1-CB 4.42Å; F55-I354 HydrophobicContact CD1-CD1 4.07Å; F55-I354 HydrophobicContact CD1-CG1 3.61Å; F55-I354 HydrophobicContact CD1-CG2 4.12Å; F55-I354 HydrophobicContact CD2-CG2 4.09Å; F55-I354 HydrophobicContact CE1-CG1 4.21Å; F55-I354 HydrophobicContact CG-CB 4.49Å; F55-I354 HydrophobicContact CG-CD1 4.38Å; F55-I354 HydrophobicContact CG-CG1 4.06Å; F55-I354 HydrophobicContact CG-CG2 3.71Å; I59-I354 HydrophobicContact CD1-CD1 4.19Å; I59-I354 HydrophobicContact CG1-CD1 4.2Å; V350-I354 HydrophobicContact CG1-CD1 3.62Å; V350-I354 HydrophobicContact CG1-CG1 4.3Å; V350-I354 WeakPolarHBondContact O-CB 3.27Å; V350-I354 WeakPolarHBondContact O-CG1 3.29Å; V350-I354 PolarHBondContact O-N 3.39Å; G351-I354 PolarHBondContact O-N 3.5Å; I352-I354 VanDerWaalsContact C-N 3.34Å; I352-I354 PolarHBondContact O-N 3.27Å; I354-T356 PolarHBondContact O-N 3.3Å; I354-S357 PolarHBondContact O-N 3.39Å; I354-S357 PolarHBondContact O-OG 2.96Å; I354-I358 HydrophobicContact CG2-CD1 3.76Å; I354-I358 WeakPolarHBondContact O-CG1 3.46Å; I354-I358 PolarHBondContact O-N 3.14Å; I354-I400 HydrophobicContact CG1-CD1 4.33Å
355	V	84.9	Confident	81.5	Confident	97 Å²	97	49.8 Å²	49.8	59%	0.588	27%	0.269	S	S	*	.	H	α-helix	trans	-63.9	-42.6	-177.4	172.9	0	0	0	0	111.4	G351 I352 R359	G351-V355 WeakPolarHBondContact O-CG2 3.4Å; G351-V355 PolarHBondContact O-N 2.87Å; I352-V355 PolarHBondContact O-N 3.32Å; V355-R359 VanDerWaalsContact O-CB 3.25Å; V355-R359 WeakPolarHBondContact O-CB 3.28Å; V355-R359 PolarHBondContact O-N 3.26Å
356	T	81.4	Confident	82	Confident	84 Å²	84	47.6 Å²	47.6	52%	0.515	26%	0.258	S	S	.	.	H	α-helix	trans	-69.1	-37.2	178.9	55.7	0	0	0	0	112.2	I352 I353 I354 G360	I352-T356 HydrophobicContact CG2-CG2 4.07Å; I352-T356 VanDerWaalsContact O-CB 3.28Å; I352-T356 WeakPolarHBondContact O-CB 3.21Å; I352-T356 VanDerWaalsContact O-CG2 3.24Å; I352-T356 WeakPolarHBondContact O-CG2 3.29Å; I352-T356 PolarHBondContact O-N 2.88Å; I352-T356 PolarHBondContact O-OG1 2.96Å; I353-T356 PolarHBondContact O-OG1 3.33Å; I354-T356 PolarHBondContact O-N 3.3Å; T356-G360 WeakPolarHBondContact O-CA 3.37Å; T356-G360 PolarHBondContact O-N 3.39Å
357	S	82.8	Confident	82.6	Confident	12 Å²	12	54.4 Å²	54.4	8%	0.084	29%	0.287	C	S	.	.	H	α-helix	trans	-67.4	-46.7	176.1	64.4	0	0	0	0	112.4	I353 I354 G360 L361	I353-S357 WeakPolarHBondContact O-CB 3.28Å; I353-S357 PolarHBondContact O-N 3.35Å; I353-S357 PolarHBondContact O-OG 2.96Å; I354-S357 PolarHBondContact O-N 3.39Å; I354-S357 PolarHBondContact O-OG 2.96Å; S357-G360 PolarHBondContact O-N 2.91Å; S357-L361 VanDerWaalsContact O-CB 3.23Å; S357-L361 WeakPolarHBondContact O-CB 3.2Å; S357-L361 PolarHBondContact O-N 3.07Å
358	I	84.4	Confident	82.8	Confident	31 Å²	31	56.3 Å²	56.3	16%	0.159	30%	0.296	C	S	.	.	H	α-helix	trans	-60	-52.4	176.1	-65.5	168.4	0	0	0	110	F48 F55 I354 G360 L361 L362 F393	F48-I358 HydrophobicContact CE2-CG2 4.4Å; F55-I358 HydrophobicContact CD2-CD1 3.94Å; F55-I358 HydrophobicContact CD2-CG1 4.24Å; F55-I358 HydrophobicContact CE2-CD1 4.24Å; F55-I358 HydrophobicContact CE2-CG1 4.02Å; I354-I358 HydrophobicContact CG2-CD1 3.76Å; I354-I358 WeakPolarHBondContact O-CG1 3.46Å; I354-I358 PolarHBondContact O-N 3.14Å; I358-G360 PolarHBondContact O-N 2.93Å; I358-L361 PolarHBondContact O-N 3.44Å; I358-L362 HydrophobicContact CG2-CD1 3.91Å; I358-L362 HydrophobicContact CG2-CG 4.34Å; I358-L362 WeakPolarHBondContact O-CB 3.2Å; I358-L362 VanDerWaalsContact O-CG 3.28Å; I358-L362 WeakPolarHBondContact O-CG 3.36Å; I358-L362 PolarHBondContact O-N 3.17Å; I358-F393 HydrophobicContact CB-CE1 4.33Å; I358-F393 HydrophobicContact CB-CZ 4.33Å; I358-F393 HydrophobicContact CG1-CE1 3.72Å; I358-F393 HydrophobicContact CG1-CZ 3.92Å; I358-F393 HydrophobicContact CG2-CZ 4.33Å
359	R	86.5	Confident	83	Confident	173 Å²	173	51.5 Å²	51.5	65%	0.653	27%	0.271	S	S	*	.	H	α-helix	trans	-61.6	-46.4	-179.4	-179.9	179.9	173.7	-177.2	-0.5	111.9	V355 L362 I363	V355-R359 VanDerWaalsContact O-CB 3.25Å; V355-R359 WeakPolarHBondContact O-CB 3.28Å; V355-R359 PolarHBondContact O-N 3.26Å; R359-L362 PolarHBondContact O-N 3.12Å; R359-I363 HydrophobicContact CG-CD1 3.81Å; R359-I363 VanDerWaalsContact O-CG1 3.28Å; R359-I363 WeakPolarHBondContact O-CG1 3.17Å; R359-I363 PolarHBondContact O-N 3.31Å; R359-I363 VanDerWaalsContact O-N 3.08Å
360	G	82.2	Confident	83.3	Confident	36 Å²	36	53.7 Å²	53.7	37%	0.371	28%	0.276	S	S	.	.	H	α-helix	trans	-57.4	-51.1	179.5	0	0	0	0	0	110.9	T356 S357 I358 I363 T364	T356-G360 WeakPolarHBondContact O-CA 3.37Å; T356-G360 PolarHBondContact O-N 3.39Å; S357-G360 PolarHBondContact O-N 2.91Å; I358-G360 PolarHBondContact O-N 2.93Å; G360-I363 PolarHBondContact O-N 2.94Å; G360-T364 PolarHBondContact O-N 2.79Å; G360-T364 VanDerWaalsContact O-N 3.08Å; G360-T364 PolarHBondContact O-OG1 2.89Å
361	L	83.9	Confident	83.6	Confident	4 Å²	4	57.5 Å²	57.5	2%	0.021	31%	0.308	C	S	.	.	H	α-helix	trans	-59.3	-52.1	178.3	-175.8	70.8	0	0	0	111.9	S357 I358 I363 T364 L365 M389 Y392 F393	S357-L361 VanDerWaalsContact O-CB 3.23Å; S357-L361 WeakPolarHBondContact O-CB 3.2Å; S357-L361 PolarHBondContact O-N 3.07Å; I358-L361 PolarHBondContact O-N 3.44Å; L361-I363 VanDerWaalsContact C-N 3.29Å; L361-I363 PolarHBondContact O-N 3.25Å; L361-T364 VanDerWaalsContact CA-OG1 3.28Å; L361-T364 WeakPolarHBondContact CA-OG1 3.21Å; L361-T364 PolarHBondContact O-N 3.34Å; L361-T364 VanDerWaalsContact O-N 3.08Å; L361-T364 PolarHBondContact O-OG1 2.98Å; L361-L365 HydrophobicContact CD1-CD1 4.35Å; L361-L365 HydrophobicContact CD1-CD2 4.43Å; L361-L365 HydrophobicContact CD1-CG 4.25Å; L361-L365 HydrophobicContact CD2-CD1 4.29Å; L361-L365 HydrophobicContact CG-CD1 3.84Å; L361-L365 HydrophobicContact CG-CG 4.12Å; L361-L365 VanDerWaalsContact O-CG 3.29Å; L361-L365 WeakPolarHBondContact O-CG 3.26Å; L361-L365 PolarHBondContact O-N 3.4Å; L361-M389 HydrophobicContact CD2-CB 4.26Å; L361-M389 HydrophobicContact CD2-CG 3.8Å; L361-Y392 HydrophobicContact CB-CD1 4.42Å; L361-Y392 HydrophobicContact CB-CE1 4.17Å; L361-Y392 HydrophobicContact CD1-CD1 4.01Å; L361-Y392 HydrophobicContact CD1-CD2 3.98Å; L361-Y392 HydrophobicContact CD1-CE1 4.35Å; L361-Y392 HydrophobicContact CD1-CE2 4.31Å; L361-Y392 HydrophobicContact CD1-CG 3.82Å; L361-Y392 HydrophobicContact CD2-CD1 3.48Å; L361-Y392 VanDerWaalsContact CD2-CD1 3.48Å; L361-Y392 HydrophobicContact CD2-CE1 4.02Å; L361-Y392 HydrophobicContact CD2-CG 3.98Å; L361-Y392 HydrophobicContact CG-CD1 4.17Å; L361-Y392 HydrophobicContact CG-CE1 4.42Å; L361-Y392 HydrophobicContact CG-CG 4.46Å; L361-F393 HydrophobicContact CD2-CD1 4.07Å; L361-F393 HydrophobicContact CD2-CD2 4.31Å; L361-F393 HydrophobicContact CD2-CE1 3.53Å; L361-F393 HydrophobicContact CD2-CE2 3.86Å; L361-F393 HydrophobicContact CD2-CG 4.47Å; L361-F393 HydrophobicContact CD2-CZ 3.45Å; L361-F393 VanDerWaalsContact CD2-CZ 3.45Å
362	L	85.7	Confident	83.6	Confident	14 Å²	14	60.5 Å²	60.5	7%	0.073	32%	0.318	C	S	.	.	H	α-helix	trans	-57.5	-41.7	-178.9	-70.1	178.9	0	0	0	112	F20 F24 F48 I358 R359 L365 T366 M389	F20-L362 HydrophobicContact CE1-CD1 4.45Å; F24-L362 HydrophobicContact CD1-CD2 4.22Å; F24-L362 HydrophobicContact CD2-CD1 4.31Å; F24-L362 HydrophobicContact CE1-CD2 3.67Å; F24-L362 HydrophobicContact CE2-CB 3.92Å; F24-L362 HydrophobicContact CE2-CD1 4.1Å; F24-L362 HydrophobicContact CE2-CD2 4.14Å; F24-L362 HydrophobicContact CE2-CG 4.27Å; F24-L362 HydrophobicContact CZ-CB 3.83Å; F24-L362 HydrophobicContact CZ-CD1 4.44Å; F24-L362 HydrophobicContact CZ-CD2 3.64Å; F24-L362 HydrophobicContact CZ-CG 4.16Å; F48-L362 HydrophobicContact CD2-CD2 4.37Å; F48-L362 HydrophobicContact CE2-CD1 4.1Å; F48-L362 HydrophobicContact CE2-CD2 4.02Å; F48-L362 HydrophobicContact CE2-CG 4.49Å; I358-L362 HydrophobicContact CG2-CD1 3.91Å; I358-L362 HydrophobicContact CG2-CG 4.34Å; I358-L362 WeakPolarHBondContact O-CB 3.2Å; I358-L362 VanDerWaalsContact O-CG 3.28Å; I358-L362 WeakPolarHBondContact O-CG 3.36Å; I358-L362 PolarHBondContact O-N 3.17Å; R359-L362 PolarHBondContact O-N 3.12Å; L362-L365 PolarHBondContact O-N 3.42Å; L362-T366 WeakPolarHBondContact O-CB 3.33Å; L362-T366 PolarHBondContact O-N 3.35Å; L362-T366 PolarHBondContact O-OG1 3.43Å; L362-M389 HydrophobicContact CD2-SD 4.42Å
363	I	85.1	Confident	83.5	Confident	70 Å²	70	57 Å²	57	36%	0.359	30%	0.302	S	S	.	.	H	α-helix	trans	-63.1	-45.6	176.2	-67.7	168.1	0	0	0	111	R359 G360 L361 T366 K367	R359-I363 HydrophobicContact CG-CD1 3.81Å; R359-I363 VanDerWaalsContact O-CG1 3.28Å; R359-I363 WeakPolarHBondContact O-CG1 3.17Å; R359-I363 PolarHBondContact O-N 3.31Å; R359-I363 VanDerWaalsContact O-N 3.08Å; G360-I363 PolarHBondContact O-N 2.94Å; L361-I363 VanDerWaalsContact C-N 3.29Å; L361-I363 PolarHBondContact O-N 3.25Å; I363-T366 PolarHBondContact O-N 2.85Å; I363-K367 HydrophobicContact CG2-CD 4.39Å; I363-K367 WeakPolarHBondContact O-CG 3.35Å; I363-K367 PolarHBondContact O-N 3.46Å
364	T	84.1	Confident	83.4	Confident	59 Å²	59	57.3 Å²	57.3	36%	0.362	31%	0.309	S	S	.	.	H	α-helix	trans	-62.8	-41.9	176.1	30.2	0	0	0	0	112.5	G360 L361 K367 F368	G360-T364 PolarHBondContact O-N 2.79Å; G360-T364 VanDerWaalsContact O-N 3.08Å; G360-T364 PolarHBondContact O-OG1 2.89Å; L361-T364 VanDerWaalsContact CA-OG1 3.28Å; L361-T364 WeakPolarHBondContact CA-OG1 3.21Å; L361-T364 PolarHBondContact O-N 3.34Å; L361-T364 VanDerWaalsContact O-N 3.08Å; L361-T364 PolarHBondContact O-OG1 2.98Å; T364-K367 PolarHBondContact O-N 3.08Å; T364-F368 WeakPolarHBondContact O-CB 3.22Å; T364-F368 PolarHBondContact O-N 3.03Å
365	L	83.9	Confident	83	Confident	9 Å²	9	61.1 Å²	61.1	5%	0.047	34%	0.336	C	S	.	.	H	α-helix	trans	-63.8	-42.5	178	-66.6	175.7	0	0	0	111.1	L361 L362 F368 F369 L385 I388 M389	L361-L365 HydrophobicContact CD1-CD1 4.35Å; L361-L365 HydrophobicContact CD1-CD2 4.43Å; L361-L365 HydrophobicContact CD1-CG 4.25Å; L361-L365 HydrophobicContact CD2-CD1 4.29Å; L361-L365 HydrophobicContact CG-CD1 3.84Å; L361-L365 HydrophobicContact CG-CG 4.12Å; L361-L365 VanDerWaalsContact O-CG 3.29Å; L361-L365 WeakPolarHBondContact O-CG 3.26Å; L361-L365 PolarHBondContact O-N 3.4Å; L362-L365 PolarHBondContact O-N 3.42Å; L365-F368 PolarHBondContact O-N 3.31Å; L365-F369 VanDerWaalsContact O-CB 3.31Å; L365-F369 WeakPolarHBondContact O-CB 3.26Å; L365-F369 PolarHBondContact O-N 3.17Å; L365-L385 HydrophobicContact CB-CD2 3.96Å; L365-L385 HydrophobicContact CD2-CB 4.27Å; L365-L385 HydrophobicContact CD2-CD2 3.3Å; L365-L385 HydrophobicContact CD2-CG 4.38Å; L365-L385 HydrophobicContact CG-CD2 4.16Å; L365-I388 HydrophobicContact CD2-CG2 4.07Å; L365-M389 HydrophobicContact CD1-CB 3.83Å; L365-M389 HydrophobicContact CD1-CG 4.09Å; L365-M389 HydrophobicContact CD1-SD 4.23Å
366	T	85.4	Confident	82.5	Confident	12 Å²	12	64.2 Å²	64.2	7%	0.074	34%	0.342	C	S	.	.	H	α-helix	trans	-62	-45.6	175.6	-61.7	0	0	0	0	111.7	F24 Q28 L362 I363 F368 F369 Y370	F24-T366 WeakPolarHBondContact CZ-OG1 3.48Å; Q28-T366 HydrophobicContact CG-CG2 4.08Å; L362-T366 WeakPolarHBondContact O-CB 3.33Å; L362-T366 PolarHBondContact O-N 3.35Å; L362-T366 PolarHBondContact O-OG1 3.43Å; I363-T366 PolarHBondContact O-N 2.85Å; T366-F368 PolarHBondContact O-N 3.25Å; T366-F369 WeakPolarHBondContact O-CB 3.47Å; T366-F369 PolarHBondContact O-N 3.29Å; T366-Y370 HydrophobicContact CG2-CD2 3.65Å; T366-Y370 HydrophobicContact CG2-CE2 3.32Å; T366-Y370 WeakPolarHBondContact O-CD2 3.3Å; T366-Y370 PolarHBondContact O-N 3.26Å
367	K	84.4	Confident	82.6	Confident	147 Å²	147	61.9 Å²	61.9	64%	0.639	33%	0.329	S	S	*	.	H	α-helix	trans	-61.9	-44.5	176.9	-73	179.8	179.5	-175.3	0	111.8	I363 T364 Y370 A371	I363-K367 HydrophobicContact CG2-CD 4.39Å; I363-K367 WeakPolarHBondContact O-CG 3.35Å; I363-K367 PolarHBondContact O-N 3.46Å; T364-K367 PolarHBondContact O-N 3.08Å; K367-Y370 PolarHBondContact O-N 3.38Å; K367-A371 WeakPolarHBondContact O-CB 3.45Å; K367-A371 PolarHBondContact O-N 3.17Å
368	F	83.1	Confident	82.7	Confident	101 Å²	101	61.5 Å²	61.5	44%	0.443	33%	0.326	S	S	.	.	H	α-helix	trans	-65.1	-40.3	178	-172.1	-91.2	0	0	0	111.9	T364 L365 T366 A371 I372 L385	T364-F368 WeakPolarHBondContact O-CB 3.22Å; T364-F368 PolarHBondContact O-N 3.03Å; L365-F368 PolarHBondContact O-N 3.31Å; T366-F368 PolarHBondContact O-N 3.25Å; F368-A371 PolarHBondContact O-N 3.17Å; F368-I372 HydrophobicContact CD1-CD1 3.82Å; F368-I372 HydrophobicContact CD2-CD1 3.68Å; F368-I372 HydrophobicContact CE1-CD1 3.42Å; F368-I372 VanDerWaalsContact CE1-CD1 3.42Å; F368-I372 HydrophobicContact CE2-CD1 3.23Å; F368-I372 HydrophobicContact CG-CD1 3.98Å; F368-I372 HydrophobicContact CZ-CD1 3.11Å; F368-I372 PolarHBondContact O-N 3.3Å; F368-L385 HydrophobicContact CB-CD2 4.48Å; F368-L385 HydrophobicContact CD1-CD2 3.83Å
369	F	85.1	Confident	82.9	Confident	0 Å²	0	61.3 Å²	61.3	0%	0	33%	0.326	C	S	.	.	H	α-helix	trans	-55.7	-58.7	174	-177.3	-100.4	0	0	0	109.8	L29 F30 Y33 L365 T366 A371 I372 S373 I381 V382 L385	L29-F369 HydrophobicContact CB-CD1 4.46Å; L29-F369 HydrophobicContact CB-CE1 4.43Å; L29-F369 HydrophobicContact CD2-CB 4.42Å; L29-F369 HydrophobicContact CD2-CD1 4.47Å; L29-F369 HydrophobicContact CD2-CD2 3.72Å; L29-F369 HydrophobicContact CD2-CE2 4.1Å; L29-F369 HydrophobicContact CD2-CG 3.93Å; L29-F369 HydrophobicContact CG-CB 4.47Å; L29-F369 HydrophobicContact CG-CD1 4.22Å; L29-F369 HydrophobicContact CG-CD2 4.34Å; L29-F369 HydrophobicContact CG-CG 4.06Å; L29-F369 WeakPolarHBondContact O-CE1 3.45Å; F30-F369 HydrophobicContact CE2-CZ 4.48Å; Y33-F369 HydrophobicContact CD2-CE1 4.09Å; Y33-F369 HydrophobicContact CD2-CZ 4.02Å; Y33-F369 AromaticContact CE2-CE1 3.66Å; Y33-F369 HydrophobicContact CE2-CE1 3.66Å; Y33-F369 AromaticContact CE2-CZ 3.75Å; Y33-F369 HydrophobicContact CE2-CZ 3.75Å; L365-F369 VanDerWaalsContact O-CB 3.31Å; L365-F369 WeakPolarHBondContact O-CB 3.26Å; L365-F369 PolarHBondContact O-N 3.17Å; T366-F369 WeakPolarHBondContact O-CB 3.47Å; T366-F369 PolarHBondContact O-N 3.29Å; F369-A371 VanDerWaalsContact C-N 3.26Å; F369-A371 PolarHBondContact O-N 3.16Å; F369-I372 PolarHBondContact O-N 3.09Å; F369-I372 VanDerWaalsContact O-N 3.15Å; F369-S373 WeakPolarHBondContact O-CA 3.38Å; F369-S373 WeakPolarHBondContact O-CB 3.34Å; F369-S373 PolarHBondContact O-N 3.36Å; F369-S373 PolarHBondContact O-OG 2.89Å; F369-I381 HydrophobicContact CD2-CG2 3.81Å; F369-I381 HydrophobicContact CE2-CG2 4.34Å; F369-V382 HydrophobicContact CD2-CG2 3.96Å; F369-V382 HydrophobicContact CE2-CG2 3.42Å; F369-V382 VanDerWaalsContact CE2-CG2 3.42Å; F369-V382 HydrophobicContact CZ-CG2 4.27Å; F369-L385 HydrophobicContact CB-CD1 3.68Å; F369-L385 HydrophobicContact CD2-CD1 3.69Å; F369-L385 HydrophobicContact CG-CD1 4.12Å
370	Y	83.8	Confident	83.1	Confident	102 Å²	102	53.8 Å²	53.8	40%	0.4	30%	0.299	S	S	.	.	H	α-helix	trans	-63	-29.1	-177.8	-70.5	-53.2	0	0	0	114.4	Q28 T366 K367	Q28-Y370 PolarHBondContact O-OH 2.65Å; T366-Y370 HydrophobicContact CG2-CD2 3.65Å; T366-Y370 HydrophobicContact CG2-CE2 3.32Å; T366-Y370 WeakPolarHBondContact O-CD2 3.3Å; T366-Y370 PolarHBondContact O-N 3.26Å; K367-Y370 PolarHBondContact O-N 3.38Å
371	A	82.3	Confident	83.4	Confident	82 Å²	82	52.6 Å²	52.6	68%	0.678	28%	0.284	S	S	*	.	H	α-helix	trans	-71.4	-29.1	178.4	0	0	0	0	0	113.3	K367 F368 F369	K367-A371 WeakPolarHBondContact O-CB 3.45Å; K367-A371 PolarHBondContact O-N 3.17Å; F368-A371 PolarHBondContact O-N 3.17Å; F369-A371 VanDerWaalsContact C-N 3.26Å; F369-A371 PolarHBondContact O-N 3.16Å
372	I	82.6	Confident	83.7	Confident	83 Å²	83	52.4 Å²	52.4	43%	0.426	28%	0.283	S	S	.	.	H	α-helix	trans	-119.2	-17.4	-169.6	-63.4	162.8	0	0	0	111.9	F368 F369 S374 I381	F368-I372 HydrophobicContact CD1-CD1 3.82Å; F368-I372 HydrophobicContact CD2-CD1 3.68Å; F368-I372 HydrophobicContact CE1-CD1 3.42Å; F368-I372 VanDerWaalsContact CE1-CD1 3.42Å; F368-I372 HydrophobicContact CE2-CD1 3.23Å; F368-I372 HydrophobicContact CG-CD1 3.98Å; F368-I372 HydrophobicContact CZ-CD1 3.11Å; F368-I372 PolarHBondContact O-N 3.3Å; F369-I372 PolarHBondContact O-N 3.09Å; F369-I372 VanDerWaalsContact O-N 3.15Å; I372-S374 PolarHBondContact O-N 2.83Å; I372-I381 HydrophobicContact CB-CD1 4.48Å; I372-I381 HydrophobicContact CG2-CD1 3.84Å; I372-I381 HydrophobicContact CG2-CG1 4.4Å; I372-I381 WeakPolarHBondContact O-CD1 3.43Å
373	S	78.8	Confident	84.1	Confident	20 Å²	20	51.7 Å²	51.7	14%	0.14	28%	0.279	C	S	.	.			trans	-65.1	117.5	-174.5	61.5	0	0	0	0	111.4	Y33 F369	Y33-S373 VanDerWaalsContact OH-C 3.23Å; Y33-S373 WeakPolarHBondContact OH-CB 3.36Å; Y33-S373 PolarHBondContact OH-O 3.49Å; Y33-S373 PolarHBondContact OH-OG 2.98Å; F369-S373 WeakPolarHBondContact O-CA 3.38Å; F369-S373 WeakPolarHBondContact O-CB 3.34Å; F369-S373 PolarHBondContact O-N 3.36Å; F369-S373 PolarHBondContact O-OG 2.89Å
374	S	79.4	Confident	84.4	Confident	60 Å²	60	52 Å²	52	42%	0.42	28%	0.281	S	S	.	.			trans	-108.9	156.1	164.5	-179.9	0	0	0	0	109	I372 K376 S377 S378	I372-S374 PolarHBondContact O-N 2.83Å; S374-K376 PolarHBondContact O-N 3.45Å; S374-K376 VanDerWaalsContact O-N 3.09Å; S374-S377 WeakPolarHBondContact CB-OG 3.48Å; S374-S377 PolarHBondContact N-OG 3.25Å; S374-S377 PolarHBondContact O-N 3.46Å; S374-S377 VanDerWaalsContact O-N 3.08Å; S374-S378 PolarHBondContact O-N 3.28Å
375	S	72.9	Confident	84.8	Confident	88 Å²	88	49.3 Å²	49.3	62%	0.615	26%	0.264	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.8	-26.8	178.6	56.8	0	0	0	0	113.6
376	K	74.9	Confident	85.2	Confident	162 Å²	162	48.9 Å²	48.9	70%	0.704	26%	0.262	S	S	*	.	T	Hydrogen-bonded Turn	trans	-87.8	-23.7	178.4	-64.3	-175.2	-179.5	174	0	114.3	N101 S374	N101-K376 PolarHBondContact ND2-O 2.75Å; S374-K376 PolarHBondContact O-N 3.45Å; S374-K376 VanDerWaalsContact O-N 3.09Å
377	S	82.5	Confident	85.7	Confident	35 Å²	35	49.4 Å²	49.4	25%	0.245	26%	0.264	C	S	.	.	T	Hydrogen-bonded Turn	trans	-112.2	-4.6	-172.9	58	0	0	0	0	114	S374 N379 V380 I381	S374-S377 WeakPolarHBondContact CB-OG 3.48Å; S374-S377 PolarHBondContact N-OG 3.25Å; S374-S377 PolarHBondContact O-N 3.46Å; S374-S377 VanDerWaalsContact O-N 3.08Å; S377-N379 VanDerWaalsContact C-N 3.32Å; S377-N379 PolarHBondContact O-N 3.41Å; S377-V380 PolarHBondContact O-N 2.94Å; S377-I381 WeakPolarHBondContact O-CG1 3.38Å; S377-I381 PolarHBondContact O-N 3.27Å; S377-I381 WeakPolarHBondContact OG-CD1 3.4Å
378	S	85.4	Confident	86.1	Confident	4 Å²	4	44.6 Å²	44.6	3%	0.028	25%	0.245	C	C	.	.	H	α-helix	trans	-51	-45.6	-176	59.6	0	0	0	0	113.3	S374 V380 I381 V382	S374-S378 PolarHBondContact O-N 3.28Å; S378-V380 PolarHBondContact O-N 3.36Å; S378-I381 PolarHBondContact O-N 3.16Å; S378-V382 VanDerWaalsContact O-CG2 3.26Å; S378-V382 WeakPolarHBondContact O-CG2 3.39Å; S378-V382 PolarHBondContact O-N 3.26Å
379	N	88.4	Confident	86.5	Confident	27 Å²	27	39.8 Å²	39.8	14%	0.144	22%	0.224	C	C	.	.	H	α-helix	trans	-60.3	-43.6	177.8	-70.4	-37.9	0	0	0	112.9	V40 F97 S377 L383	V40-N379 HydrophobicContact CG2-CB 4.18Å; F97-N379 HydrophobicContact CD1-CB 4.24Å; F97-N379 HydrophobicContact CG-CB 4.37Å; S377-N379 VanDerWaalsContact C-N 3.32Å; S377-N379 PolarHBondContact O-N 3.41Å; N379-L383 WeakPolarHBondContact O-CG 3.29Å; N379-L383 PolarHBondContact O-N 3.45Å; N379-L383 VanDerWaalsContact O-N 3.16Å
380	V	90.4	Very high	86.9	Confident	15 Å²	15	39.8 Å²	39.8	9%	0.091	22%	0.224	C	C	.	.	H	α-helix	trans	-66.9	-44.7	178.3	178	0	0	0	0	110	I94 F97 I98 S377 S378 V382 L383 L384	I94-V380 HydrophobicContact CG2-CG1 4.41Å; F97-V380 HydrophobicContact CB-CG2 3.64Å; I98-V380 HydrophobicContact CD1-CG1 4.18Å; I98-V380 HydrophobicContact CG1-CG1 3.79Å; I98-V380 HydrophobicContact CG1-CG2 4.01Å; S377-V380 PolarHBondContact O-N 2.94Å; S378-V380 PolarHBondContact O-N 3.36Å; V380-V382 VanDerWaalsContact C-N 3.31Å; V380-V382 PolarHBondContact O-N 2.95Å; V380-L383 PolarHBondContact O-N 3.48Å; V380-L384 HydrophobicContact CG1-CD1 4.06Å; V380-L384 HydrophobicContact CG1-CG 4.47Å; V380-L384 WeakPolarHBondContact O-CG 3.36Å; V380-L384 PolarHBondContact O-N 3.42Å
381	I	89.8	Confident	87.4	Confident	10 Å²	10	35.1 Å²	35.1	5%	0.051	21%	0.206	C	C	.	.	H	α-helix	trans	-62	-41.7	-179.7	-65.4	164.6	0	0	0	110.4	F369 I372 S377 S378 L384 L385	F369-I381 HydrophobicContact CD2-CG2 3.81Å; F369-I381 HydrophobicContact CE2-CG2 4.34Å; I372-I381 HydrophobicContact CB-CD1 4.48Å; I372-I381 HydrophobicContact CG2-CD1 3.84Å; I372-I381 HydrophobicContact CG2-CG1 4.4Å; I372-I381 WeakPolarHBondContact O-CD1 3.43Å; S377-I381 WeakPolarHBondContact O-CG1 3.38Å; S377-I381 PolarHBondContact O-N 3.27Å; S377-I381 WeakPolarHBondContact OG-CD1 3.4Å; S378-I381 PolarHBondContact O-N 3.16Å; I381-L384 WeakPolarHBondContact O-CB 3.4Å; I381-L384 PolarHBondContact O-N 2.75Å; I381-L385 HydrophobicContact CG2-CD1 4.04Å; I381-L385 HydrophobicContact CG2-CG 4.39Å; I381-L385 VanDerWaalsContact O-CG 3.24Å; I381-L385 WeakPolarHBondContact O-CG 3.36Å; I381-L385 PolarHBondContact O-N 2.74Å
382	V	90	Very high	87.9	Confident	0 Å²	0	32.5 Å²	32.5	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-63.2	-43.6	176.3	165.2	0	0	0	0	112.7	F25 L29 F30 V40 F44 F369 S378 V380 L384 L385 A386	F25-V382 HydrophobicContact CD2-CG1 4.3Å; F25-V382 HydrophobicContact CE2-CB 4.4Å; F25-V382 HydrophobicContact CE2-CG1 3.49Å; F25-V382 VanDerWaalsContact CE2-CG1 3.49Å; F25-V382 HydrophobicContact CE2-CG2 4.15Å; F25-V382 HydrophobicContact CZ-CG1 4.35Å; L29-V382 HydrophobicContact CD2-CG2 3.56Å; F30-V382 HydrophobicContact CD2-CG2 4.27Å; F30-V382 HydrophobicContact CE2-CB 4.31Å; F30-V382 HydrophobicContact CE2-CG2 3.35Å; F30-V382 HydrophobicContact CZ-CG2 4.04Å; V40-V382 HydrophobicContact CG1-CB 3.98Å; V40-V382 HydrophobicContact CG1-CG1 3.48Å; V40-V382 VanDerWaalsContact CG1-CG1 3.48Å; F44-V382 HydrophobicContact CB-CG1 4.29Å; F44-V382 HydrophobicContact CD2-CG1 4.09Å; F44-V382 HydrophobicContact CG-CG1 4.43Å; F369-V382 HydrophobicContact CD2-CG2 3.96Å; F369-V382 HydrophobicContact CE2-CG2 3.42Å; F369-V382 VanDerWaalsContact CE2-CG2 3.42Å; F369-V382 HydrophobicContact CZ-CG2 4.27Å; S378-V382 VanDerWaalsContact O-CG2 3.26Å; S378-V382 WeakPolarHBondContact O-CG2 3.39Å; S378-V382 PolarHBondContact O-N 3.26Å; V380-V382 VanDerWaalsContact C-N 3.31Å; V380-V382 PolarHBondContact O-N 2.95Å; V382-L384 VanDerWaalsContact C-N 3.28Å; V382-L384 PolarHBondContact O-N 2.91Å; V382-L385 CarbonylContact O-C 3.59Å; V382-L385 WeakPolarHBondContact O-CB 3.44Å; V382-L385 PolarHBondContact O-N 2.85Å; V382-L385 VanDerWaalsContact O-N 3.17Å; V382-A386 PolarHBondContact O-N 3.45Å
383	L	93	Very high	88.3	Confident	0 Å²	0	28.5 Å²	28.5	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-65.5	-36	177.1	-68.9	171.2	0	0	0	111.3	V40 I43 V90 I94 F97 N379 V380 L385 A386 Q387	V40-L383 HydrophobicContact CG1-CD2 4.12Å; V40-L383 HydrophobicContact CG1-CG 4.04Å; V40-L383 HydrophobicContact CG2-CD1 4.23Å; V40-L383 HydrophobicContact CG2-CD2 4.49Å; V40-L383 HydrophobicContact CG2-CG 4.33Å; I43-L383 HydrophobicContact CB-CD2 4.21Å; I43-L383 HydrophobicContact CD1-CD2 4.2Å; I43-L383 HydrophobicContact CG2-CD2 3.87Å; V90-L383 WeakPolarHBondContact CG1-O 3.1Å; I94-L383 HydrophobicContact CD1-CB 4.25Å; I94-L383 HydrophobicContact CG1-CB 3.5Å; I94-L383 HydrophobicContact CG1-CD1 4.34Å; F97-L383 HydrophobicContact CD2-CD1 3.45Å; F97-L383 VanDerWaalsContact CD2-CD1 3.45Å; F97-L383 HydrophobicContact CE2-CD1 3.9Å; F97-L383 HydrophobicContact CG-CD1 4.49Å; N379-L383 WeakPolarHBondContact O-CG 3.29Å; N379-L383 PolarHBondContact O-N 3.45Å; N379-L383 VanDerWaalsContact O-N 3.16Å; V380-L383 PolarHBondContact O-N 3.48Å; L383-L385 VanDerWaalsContact C-N 3.35Å; L383-A386 WeakPolarHBondContact O-CB 3.29Å; L383-A386 PolarHBondContact O-N 2.95Å; L383-Q387 PolarHBondContact O-N 3.47Å
384	L	92.8	Very high	88.8	Confident	76 Å²	76	27.6 Å²	27.6	40%	0.398	15%	0.152	S	C	.	.	H	α-helix	trans	-63.1	-40.3	170.9	-71.9	169.1	0	0	0	111.9	I94 V380 I381 V382 Q387 I388	I94-L384 HydrophobicContact CD1-CD2 3.86Å; I94-L384 HydrophobicContact CD1-CG 4.29Å; I94-L384 HydrophobicContact CG2-CD2 4.37Å; V380-L384 HydrophobicContact CG1-CD1 4.06Å; V380-L384 HydrophobicContact CG1-CG 4.47Å; V380-L384 WeakPolarHBondContact O-CG 3.36Å; V380-L384 PolarHBondContact O-N 3.42Å; I381-L384 WeakPolarHBondContact O-CB 3.4Å; I381-L384 PolarHBondContact O-N 2.75Å; V382-L384 VanDerWaalsContact C-N 3.28Å; V382-L384 PolarHBondContact O-N 2.91Å; L384-Q387 WeakPolarHBondContact O-CB 3.41Å; L384-Q387 PolarHBondContact O-N 3.29Å; L384-I388 VanDerWaalsContact O-CG1 3.31Å; L384-I388 WeakPolarHBondContact O-CG1 3.45Å; L384-I388 PolarHBondContact O-N 3.41Å
385	L	90.8	Very high	89.3	Confident	2 Å²	2	24.8 Å²	24.8	1%	0.01	13%	0.132	C	C	.	.	H	α-helix	trans	-65.6	-40.6	174.4	-69	167.9	0	0	0	111.3	L29 L365 F368 F369 I381 V382 L383 Q387 I388 M389	L29-L385 HydrophobicContact CD2-CD1 3.93Å; L365-L385 HydrophobicContact CB-CD2 3.96Å; L365-L385 HydrophobicContact CD2-CB 4.27Å; L365-L385 HydrophobicContact CD2-CD2 3.3Å; L365-L385 HydrophobicContact CD2-CG 4.38Å; L365-L385 HydrophobicContact CG-CD2 4.16Å; F368-L385 HydrophobicContact CB-CD2 4.48Å; F368-L385 HydrophobicContact CD1-CD2 3.83Å; F369-L385 HydrophobicContact CB-CD1 3.68Å; F369-L385 HydrophobicContact CD2-CD1 3.69Å; F369-L385 HydrophobicContact CG-CD1 4.12Å; I381-L385 HydrophobicContact CG2-CD1 4.04Å; I381-L385 HydrophobicContact CG2-CG 4.39Å; I381-L385 VanDerWaalsContact O-CG 3.24Å; I381-L385 WeakPolarHBondContact O-CG 3.36Å; I381-L385 PolarHBondContact O-N 2.74Å; V382-L385 CarbonylContact O-C 3.59Å; V382-L385 WeakPolarHBondContact O-CB 3.44Å; V382-L385 PolarHBondContact O-N 2.85Å; V382-L385 VanDerWaalsContact O-N 3.17Å; L383-L385 VanDerWaalsContact C-N 3.35Å; L385-Q387 VanDerWaalsContact C-N 3.32Å; L385-Q387 PolarHBondContact O-N 3.5Å; L385-I388 PolarHBondContact O-N 2.93Å; L385-M389 WeakPolarHBondContact O-CB 3.41Å; L385-M389 PolarHBondContact O-N 3.39Å
386	A	93.1	Very high	90.1	Very high	0 Å²	0	20.7 Å²	20.7	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-60.3	-43.1	173.4	0	0	0	0	0	111.2	F44 V382 L383 M389 G390	F44-A386 HydrophobicContact CB-CB 4.49Å; F44-A386 HydrophobicContact CD2-CB 3.9Å; V382-A386 PolarHBondContact O-N 3.45Å; L383-A386 WeakPolarHBondContact O-CB 3.29Å; L383-A386 PolarHBondContact O-N 2.95Å; A386-M389 PolarHBondContact O-N 3.44Å; A386-G390 PolarHBondContact O-N 3Å
387	Q	95.2	Very high	90.6	Very high	24 Å²	24	13.1 Å²	13.1	11%	0.112	7%	0.07	C	C	.	.	H	α-helix	trans	-59.5	-57.1	174.8	-172.2	67.6	14.9	0	0	110.7	L86 V90 I94 L383 L384 L385 M389 G390 M391	L86-Q387 PolarHBondContact O-NE2 3.05Å; L86-Q387 PolarHBondContact O-OE1 3.46Å; V90-Q387 VanDerWaalsContact CB-OE1 3.29Å; V90-Q387 HydrophobicContact CG1-CB 3.83Å; I94-Q387 HydrophobicContact CD1-CB 4.44Å; L383-Q387 PolarHBondContact O-N 3.47Å; L384-Q387 WeakPolarHBondContact O-CB 3.41Å; L384-Q387 PolarHBondContact O-N 3.29Å; L385-Q387 VanDerWaalsContact C-N 3.32Å; L385-Q387 PolarHBondContact O-N 3.5Å; Q387-M389 PolarHBondContact O-N 3.32Å; Q387-G390 PolarHBondContact O-N 3.5Å; Q387-M391 HydrophobicContact CG-CG 4.33Å; Q387-M391 WeakPolarHBondContact O-CG 3.48Å; Q387-M391 PolarHBondContact O-N 3.44Å
388	I	93.1	Very high	90.7	Very high	46 Å²	46	11.5 Å²	11.5	24%	0.236	6%	0.059	C	C	.	.	H	α-helix	trans	-55.4	-43.8	-179.8	-71.8	167.8	0	0	0	110.4	L157 L365 L384 L385 Y392	L157-I388 HydrophobicContact CD1-CB 4.49Å; L157-I388 HydrophobicContact CD1-CG1 4.32Å; L157-I388 HydrophobicContact CD1-CG2 4.23Å; L365-I388 HydrophobicContact CD2-CG2 4.07Å; L384-I388 VanDerWaalsContact O-CG1 3.31Å; L384-I388 WeakPolarHBondContact O-CG1 3.45Å; L384-I388 PolarHBondContact O-N 3.41Å; L385-I388 PolarHBondContact O-N 2.93Å; I388-Y392 WeakPolarHBondContact O-CB 3.26Å; I388-Y392 PolarHBondContact O-N 3.35Å
389	M	92.3	Very high	90.4	Very high	0 Å²	0	12.1 Å²	12.1	0%	0	6%	0.062	C	C	.	.	H	α-helix	trans	-61.6	-52.3	-179.3	-179.4	-179.2	71.4	0	0	112.7	F44 T47 F48 L361 L362 L365 L385 A386 Q387 M391 Y392 F393	F44-M389 HydrophobicContact CD2-CE 4.46Å; F44-M389 HydrophobicContact CE2-CE 4.11Å; F44-M389 HydrophobicContact CE2-SD 4.23Å; F44-M389 HydrophobicContact CZ-CE 4.26Å; F44-M389 HydrophobicContact CZ-SD 4.12Å; T47-M389 HydrophobicContact CG2-CE 4.02Å; F48-M389 HydrophobicContact CB-CE 3.72Å; F48-M389 HydrophobicContact CB-SD 4.37Å; F48-M389 HydrophobicContact CD2-CE 4.23Å; F48-M389 HydrophobicContact CD2-SD 3.77Å; F48-M389 HydrophobicContact CG-CE 4.5Å; L361-M389 HydrophobicContact CD2-CB 4.26Å; L361-M389 HydrophobicContact CD2-CG 3.8Å; L362-M389 HydrophobicContact CD2-SD 4.42Å; L365-M389 HydrophobicContact CD1-CB 3.83Å; L365-M389 HydrophobicContact CD1-CG 4.09Å; L365-M389 HydrophobicContact CD1-SD 4.23Å; L385-M389 WeakPolarHBondContact O-CB 3.41Å; L385-M389 PolarHBondContact O-N 3.39Å; A386-M389 PolarHBondContact O-N 3.44Å; Q387-M389 PolarHBondContact O-N 3.32Å; M389-M391 PolarHBondContact O-N 2.92Å; M389-Y392 WeakPolarHBondContact O-CB 3.08Å; M389-Y392 PolarHBondContact O-N 2.88Å; M389-F393 HydrophobicContact CG-CD2 3.63Å; M389-F393 HydrophobicContact CG-CE2 3.3Å; M389-F393 HydrophobicContact CG-CZ 4.19Å; M389-F393 VanDerWaalsContact O-CD2 3.25Å; M389-F393 WeakPolarHBondContact O-CD2 3.49Å; M389-F393 WeakPolarHBondContact O-CG 3.35Å; M389-F393 PolarHBondContact O-N 3.33Å; M389-F393 HydrophobicContact SD-CE2 3.98Å
390	G	93.9	Very high	90	Very high	0 Å²	0	11.2 Å²	11.2	0%	0	6%	0.057	C	C	.	.	H	α-helix	trans	-66.6	-38.9	-179.2	0	0	0	0	0	112.5	A386 Q387 Y392 F393 V394	A386-G390 PolarHBondContact O-N 3Å; Q387-G390 PolarHBondContact O-N 3.5Å; G390-Y392 VanDerWaalsContact C-N 3.33Å; G390-Y392 PolarHBondContact O-N 3.48Å; G390-F393 PolarHBondContact O-N 3.44Å; G390-V394 VanDerWaalsContact O-CG2 3.26Å; G390-V394 WeakPolarHBondContact O-CG2 3.43Å; G390-V394 PolarHBondContact O-N 3.14Å
391	M	93.8	Very high	89.3	Confident	4 Å²	4	11.2 Å²	11.2	2%	0.02	6%	0.055	C	C	.	.	H	α-helix	trans	-63.6	-41	176.1	-56.3	-74.4	-71.8	0	0	111.1	L86 V150 I153 Q387 M389 S395	L86-M391 HydrophobicContact CB-SD 4.08Å; L86-M391 HydrophobicContact CD1-SD 4.09Å; L86-M391 HydrophobicContact CD2-CG 4.37Å; L86-M391 HydrophobicContact CD2-SD 4.46Å; L86-M391 HydrophobicContact CG-SD 4.44Å; V150-M391 HydrophobicContact CB-CE 3.97Å; V150-M391 HydrophobicContact CB-SD 4.06Å; V150-M391 HydrophobicContact CG1-CE 3.89Å; V150-M391 HydrophobicContact CG1-SD 3.53Å; V150-M391 VanDerWaalsContact CG1-SD 3.53Å; V150-M391 HydrophobicContact CG2-CE 3.95Å; V150-M391 HydrophobicContact CG2-SD 3.8Å; I153-M391 HydrophobicContact CB-CE 3.5Å; I153-M391 HydrophobicContact CD1-CE 3.74Å; I153-M391 HydrophobicContact CG1-CE 4.15Å; I153-M391 HydrophobicContact CG2-CE 3.67Å; Q387-M391 HydrophobicContact CG-CG 4.33Å; Q387-M391 WeakPolarHBondContact O-CG 3.48Å; Q387-M391 PolarHBondContact O-N 3.44Å; M389-M391 PolarHBondContact O-N 2.92Å; M391-S395 WeakPolarHBondContact O-CB 3.46Å; M391-S395 PolarHBondContact O-N 2.94Å; M391-S395 PolarHBondContact O-OG 2.96Å
392	Y	91.9	Very high	88.3	Confident	26 Å²	26	13.2 Å²	13.2	10%	0.102	7%	0.065	C	C	.	.	H	α-helix	trans	-61.6	-46.2	175	176.7	-83.4	0	0	0	111.8	M158 L361 I388 M389 G390 S395 S396	M158-Y392 HydrophobicContact CB-CD2 3.95Å; M158-Y392 HydrophobicContact CB-CE2 3.85Å; M158-Y392 HydrophobicContact CG-CD2 4.22Å; M158-Y392 HydrophobicContact CG-CE2 3.62Å; M158-Y392 HydrophobicContact SD-CE2 4.49Å; L361-Y392 HydrophobicContact CB-CD1 4.42Å; L361-Y392 HydrophobicContact CB-CE1 4.17Å; L361-Y392 HydrophobicContact CD1-CD1 4.01Å; L361-Y392 HydrophobicContact CD1-CD2 3.98Å; L361-Y392 HydrophobicContact CD1-CE1 4.35Å; L361-Y392 HydrophobicContact CD1-CE2 4.31Å; L361-Y392 HydrophobicContact CD1-CG 3.82Å; L361-Y392 HydrophobicContact CD2-CD1 3.48Å; L361-Y392 VanDerWaalsContact CD2-CD1 3.48Å; L361-Y392 HydrophobicContact CD2-CE1 4.02Å; L361-Y392 HydrophobicContact CD2-CG 3.98Å; L361-Y392 HydrophobicContact CG-CD1 4.17Å; L361-Y392 HydrophobicContact CG-CE1 4.42Å; L361-Y392 HydrophobicContact CG-CG 4.46Å; I388-Y392 WeakPolarHBondContact O-CB 3.26Å; I388-Y392 PolarHBondContact O-N 3.35Å; M389-Y392 WeakPolarHBondContact O-CB 3.08Å; M389-Y392 PolarHBondContact O-N 2.88Å; G390-Y392 VanDerWaalsContact C-N 3.33Å; G390-Y392 PolarHBondContact O-N 3.48Å; Y392-S395 PolarHBondContact O-N 3.18Å; Y392-S396 WeakPolarHBondContact CE1-OG 3.35Å; Y392-S396 WeakPolarHBondContact O-CB 3.23Å; Y392-S396 PolarHBondContact O-N 3.25Å; Y392-S396 PolarHBondContact O-OG 2.95Å
393	F	90.9	Very high	87.2	Confident	0 Å²	0	15 Å²	15	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-69	-42	-178.8	-70.5	-40.4	0	0	0	112.6	F48 F55 I358 L361 M389 G390 S395 S396 V397	F48-F393 HydrophobicContact CD2-CE2 4.49Å; F55-F393 HydrophobicContact CE2-CB 4.15Å; F55-F393 AromaticContact CE2-CD1 3.37Å; F55-F393 HydrophobicContact CE2-CD1 3.37Å; F55-F393 AromaticContact CE2-CE1 3.83Å; F55-F393 HydrophobicContact CE2-CE1 3.83Å; F55-F393 AromaticContact CE2-CG 3.89Å; F55-F393 HydrophobicContact CE2-CG 3.89Å; F55-F393 HydrophobicContact CZ-CB 4.3Å; F55-F393 AromaticContact CZ-CD1 3.65Å; F55-F393 HydrophobicContact CZ-CD1 3.65Å; F55-F393 HydrophobicContact CZ-CE1 4.34Å; F55-F393 HydrophobicContact CZ-CG 4.31Å; I358-F393 HydrophobicContact CB-CE1 4.33Å; I358-F393 HydrophobicContact CB-CZ 4.33Å; I358-F393 HydrophobicContact CG1-CE1 3.72Å; I358-F393 HydrophobicContact CG1-CZ 3.92Å; I358-F393 HydrophobicContact CG2-CZ 4.33Å; L361-F393 HydrophobicContact CD2-CD1 4.07Å; L361-F393 HydrophobicContact CD2-CD2 4.31Å; L361-F393 HydrophobicContact CD2-CE1 3.53Å; L361-F393 HydrophobicContact CD2-CE2 3.86Å; L361-F393 HydrophobicContact CD2-CG 4.47Å; L361-F393 HydrophobicContact CD2-CZ 3.45Å; L361-F393 VanDerWaalsContact CD2-CZ 3.45Å; M389-F393 HydrophobicContact CG-CD2 3.63Å; M389-F393 HydrophobicContact CG-CE2 3.3Å; M389-F393 HydrophobicContact CG-CZ 4.19Å; M389-F393 VanDerWaalsContact O-CD2 3.25Å; M389-F393 WeakPolarHBondContact O-CD2 3.49Å; M389-F393 WeakPolarHBondContact O-CG 3.35Å; M389-F393 PolarHBondContact O-N 3.33Å; M389-F393 HydrophobicContact SD-CE2 3.98Å; G390-F393 PolarHBondContact O-N 3.44Å; F393-S395 VanDerWaalsContact C-N 3.27Å; F393-S395 PolarHBondContact O-N 2.83Å; F393-S396 PolarHBondContact O-N 2.98Å; F393-V397 WeakPolarHBondContact O-CG2 3.37Å; F393-V397 PolarHBondContact O-N 3.29Å; F393-V397 VanDerWaalsContact O-N 3.09Å
394	V	90.9	Very high	86	Confident	1 Å²	1	15.4 Å²	15.4	1%	0.006	8%	0.079	C	C	.	.	H	α-helix	trans	-56.4	-44.7	171.7	174.3	0	0	0	0	110.8	M54 I82 L86 I147 V150 G390 V397 L398	M54-V394 HydrophobicContact CE-CB 3.96Å; M54-V394 HydrophobicContact CE-CG1 4.32Å; M54-V394 HydrophobicContact CE-CG2 3.53Å; I82-V394 HydrophobicContact CG1-CG2 4.16Å; I82-V394 HydrophobicContact CG2-CG2 4.25Å; L86-V394 HydrophobicContact CD1-CG2 3.9Å; I147-V394 HydrophobicContact CD1-CG1 4.34Å; I147-V394 HydrophobicContact CG1-CG1 3.94Å; V150-V394 HydrophobicContact CG1-CB 3.9Å; V150-V394 HydrophobicContact CG1-CG1 3.69Å; V150-V394 HydrophobicContact CG1-CG2 4.23Å; G390-V394 VanDerWaalsContact O-CG2 3.26Å; G390-V394 WeakPolarHBondContact O-CG2 3.43Å; G390-V394 PolarHBondContact O-N 3.14Å; V394-V397 PolarHBondContact O-N 2.95Å; V394-L398 WeakPolarHBondContact O-CG 3.45Å; V394-L398 PolarHBondContact O-N 3.05Å; V394-L398 VanDerWaalsContact O-N 3.17Å
395	S	90	Very high	84.7	Confident	0 Å²	0	13.1 Å²	13.1	0%	0	7%	0.069	C	C	.	.	H	α-helix	trans	-69.6	-34.9	179.7	-60.4	0	0	0	0	113.4	G151 G154 V155 M391 Y392 F393 V397 L398 L399	G151-S395 WeakPolarHBondContact CA-OG 3.33Å; G151-S395 PolarHBondContact O-OG 3.35Å; G154-S395 VanDerWaalsContact C-CB 3.43Å; G154-S395 WeakPolarHBondContact CA-OG 3.34Å; V155-S395 PolarHBondContact N-OG 3.45Å; V155-S395 VanDerWaalsContact N-OG 3.12Å; M391-S395 WeakPolarHBondContact O-CB 3.46Å; M391-S395 PolarHBondContact O-N 2.94Å; M391-S395 PolarHBondContact O-OG 2.96Å; Y392-S395 PolarHBondContact O-N 3.18Å; F393-S395 VanDerWaalsContact C-N 3.27Å; F393-S395 PolarHBondContact O-N 2.83Å; S395-V397 VanDerWaalsContact C-N 3.3Å; S395-V397 PolarHBondContact O-N 3.2Å; S395-L398 WeakPolarHBondContact O-CB 3.3Å; S395-L398 PolarHBondContact O-N 2.92Å; S395-L399 WeakPolarHBondContact O-CG 3.35Å; S395-L399 PolarHBondContact O-N 3.21Å; S395-L399 VanDerWaalsContact O-N 3.09Å
396	S	88	Confident	83.6	Confident	3 Å²	3	18.4 Å²	18.4	2%	0.021	10%	0.097	C	C	.	.	H	α-helix	trans	-61.7	-41.9	175	-61.2	0	0	0	0	110.8	Y392 F393 L399 I400	Y392-S396 WeakPolarHBondContact CE1-OG 3.35Å; Y392-S396 WeakPolarHBondContact O-CB 3.23Å; Y392-S396 PolarHBondContact O-N 3.25Å; Y392-S396 PolarHBondContact O-OG 2.95Å; F393-S396 PolarHBondContact O-N 2.98Å; S396-L399 PolarHBondContact O-N 2.92Å; S396-I400 WeakPolarHBondContact O-CB 3.44Å; S396-I400 WeakPolarHBondContact O-CD1 3.45Å; S396-I400 WeakPolarHBondContact O-CG1 3.41Å; S396-I400 PolarHBondContact O-N 3.41Å
397	V	86.1	Confident	82.4	Confident	2 Å²	2	24.3 Å²	24.3	1%	0.012	12%	0.124	C	C	.	.	H	α-helix	trans	-62.7	-42.8	175	169.1	0	0	0	0	111.7	M54 F55 I58 W75 F393 V394 S395 L399 I400 R401	M54-V397 HydrophobicContact CB-CG2 3.87Å; M54-V397 HydrophobicContact CE-CB 4.31Å; M54-V397 HydrophobicContact CE-CG2 4.08Å; F55-V397 HydrophobicContact CD1-CG2 3.98Å; F55-V397 HydrophobicContact CE1-CG2 3.77Å; F55-V397 HydrophobicContact CZ-CG2 4.44Å; I58-V397 HydrophobicContact CD1-CB 4.37Å; I58-V397 HydrophobicContact CD1-CG1 4.05Å; I58-V397 HydrophobicContact CD1-CG2 3.94Å; W75-V397 HydrophobicContact CH2-CG1 3.99Å; W75-V397 HydrophobicContact CZ3-CG1 4.21Å; F393-V397 WeakPolarHBondContact O-CG2 3.37Å; F393-V397 PolarHBondContact O-N 3.29Å; F393-V397 VanDerWaalsContact O-N 3.09Å; V394-V397 PolarHBondContact O-N 2.95Å; S395-V397 VanDerWaalsContact C-N 3.3Å; S395-V397 PolarHBondContact O-N 3.2Å; V397-L399 VanDerWaalsContact C-N 3.29Å; V397-L399 PolarHBondContact O-N 3.26Å; V397-I400 PolarHBondContact O-N 2.94Å; V397-R401 PolarHBondContact O-N 3.27Å
398	L	83.9	Confident	81.3	Confident	2 Å²	2	25 Å²	25	1%	0.01	13%	0.126	C	C	.	.	H	α-helix	trans	-58.1	-40.8	175.9	-67.5	177.3	0	0	0	112.3	I147 V394 S395 L416 L419 F421 Y424	I147-L398 HydrophobicContact CD1-CD2 4.28Å; I147-L398 HydrophobicContact CG1-CD2 4.3Å; V394-L398 WeakPolarHBondContact O-CG 3.45Å; V394-L398 PolarHBondContact O-N 3.05Å; V394-L398 VanDerWaalsContact O-N 3.17Å; S395-L398 WeakPolarHBondContact O-CB 3.3Å; S395-L398 PolarHBondContact O-N 2.92Å; L398-L416 HydrophobicContact CD2-CD1 3.84Å; L398-L416 HydrophobicContact CD2-CD2 3.7Å; L398-L416 HydrophobicContact CD2-CG 4.35Å; L398-L419 HydrophobicContact CD2-CD1 4.07Å; L398-F421 HydrophobicContact CD2-CE1 4.17Å; L398-Y424 HydrophobicContact CD1-CE1 4.47Å
399	L	80.8	Confident	80.4	Confident	16 Å²	16	26.4 Å²	26.4	8%	0.084	13%	0.129	C	C	.	.	H	α-helix	trans	-79.8	-35.9	-179.4	-64.8	176.2	0	0	0	112.9	V155 M158 S395 S396 V397 R401 M402 F428	V155-L399 HydrophobicContact CG2-CD1 4.16Å; V155-L399 HydrophobicContact CG2-CD2 4.39Å; V155-L399 HydrophobicContact CG2-CG 4.26Å; M158-L399 HydrophobicContact CE-CD1 4.32Å; M158-L399 HydrophobicContact SD-CD1 3.63Å; S395-L399 WeakPolarHBondContact O-CG 3.35Å; S395-L399 PolarHBondContact O-N 3.21Å; S395-L399 VanDerWaalsContact O-N 3.09Å; S396-L399 PolarHBondContact O-N 2.92Å; V397-L399 VanDerWaalsContact C-N 3.29Å; V397-L399 PolarHBondContact O-N 3.26Å; L399-R401 PolarHBondContact O-N 2.86Å; L399-M402 PolarHBondContact O-N 3.41Å; L399-M402 VanDerWaalsContact O-N 3.17Å; L399-F428 HydrophobicContact CD1-CD2 4.09Å
400	I	78.9	Confident	79.7	Confident	8 Å²	8	30.3 Å²	30.3	4%	0.041	15%	0.153	C	C	.	.	H	α-helix	trans	-62.2	-31.8	177.7	-73.7	165.6	0	0	0	111.1	F55 I58 V350 I353 I354 S396 V397 M402 S403 M404	F55-I400 HydrophobicContact CD1-CD1 4.39Å; F55-I400 HydrophobicContact CE1-CD1 3.9Å; I58-I400 HydrophobicContact CD1-CG2 4.31Å; V350-I400 HydrophobicContact CG1-CG2 4.18Å; V350-I400 HydrophobicContact CG2-CG2 4.36Å; I353-I400 HydrophobicContact CG2-CD1 3.97Å; I353-I400 HydrophobicContact CG2-CG1 4.09Å; I354-I400 HydrophobicContact CG1-CD1 4.33Å; S396-I400 WeakPolarHBondContact O-CB 3.44Å; S396-I400 WeakPolarHBondContact O-CD1 3.45Å; S396-I400 WeakPolarHBondContact O-CG1 3.41Å; S396-I400 PolarHBondContact O-N 3.41Å; V397-I400 PolarHBondContact O-N 2.94Å; I400-M402 PolarHBondContact O-N 3.36Å; I400-M402 VanDerWaalsContact O-N 3.14Å; I400-S403 WeakPolarHBondContact O-CA 3.44Å; I400-S403 WeakPolarHBondContact O-CB 3.47Å; I400-S403 PolarHBondContact O-N 3.36Å; I400-M404 HydrophobicContact CG2-CE 4.17Å; I400-M404 HydrophobicContact CG2-CG 4.45Å; I400-M404 HydrophobicContact CG2-SD 4.39Å; I400-M404 PolarHBondContact O-N 3.3Å
401	R	76.4	Confident	79	Confident	15 Å²	15	31 Å²	31	6%	0.057	16%	0.156	C	C	.	.	G	3₁₀ helix	trans	-49.2	-40.6	173.7	-179.9	-172.6	173.4	-104.2	4.1	112.8	V397 L399 S403 M404 R409 I412 T413 F421	V397-R401 PolarHBondContact O-N 3.27Å; L399-R401 PolarHBondContact O-N 2.86Å; R401-S403 PolarHBondContact O-N 3.22Å; R401-M404 PolarHBondContact O-N 3.37Å; R401-R409 HydrophobicContact CG-CB 4.44Å; R401-I412 HydrophobicContact CB-CG2 4.41Å; R401-I412 HydrophobicContact CG-CG2 4.21Å; R401-T413 PolarHBondContact NE-OG1 3.49Å; R401-T413 PolarHBondContact NH2-OG1 2.92Å; R401-F421 VanDerWaalsContact CZ-CE2 3.43Å; R401-F421 VanDerWaalsContact NH1-CG 3.25Å
402	M	67.5	Low	78.3	Confident	52 Å²	52	30.9 Å²	30.9	26%	0.256	16%	0.156	S	C	.	.	G	3₁₀ helix	trans	-74.6	-14.2	-179.1	-75	-65.3	-166.3	0	0	113.6	L399 I400 F421 H425	L399-M402 PolarHBondContact O-N 3.41Å; L399-M402 VanDerWaalsContact O-N 3.17Å; I400-M402 PolarHBondContact O-N 3.36Å; I400-M402 VanDerWaalsContact O-N 3.14Å; M402-F421 HydrophobicContact CE-CB 3.2Å; M402-F421 HydrophobicContact CE-CG 4.13Å; M402-H425 VanDerWaalsContact CB-NE2 3.26Å; M402-H425 WeakPolarHBondContact CB-NE2 3.21Å; M402-H425 WeakPolarHBondContact CG-NE2 3.34Å
403	S	67.4	Low	77.7	Confident	37 Å²	37	31.7 Å²	31.7	26%	0.259	16%	0.163	S	C	.	.	G	3₁₀ helix	trans	-89.9	-3.4	174.5	-50.8	0	0	0	0	112.7	I400 R401	I400-S403 WeakPolarHBondContact O-CA 3.44Å; I400-S403 WeakPolarHBondContact O-CB 3.47Å; I400-S403 PolarHBondContact O-N 3.36Å; R401-S403 PolarHBondContact O-N 3.22Å
404	M	68.6	Low	77.2	Confident	9 Å²	9	37.5 Å²	37.5	4%	0.044	19%	0.191	C	C	.	.	S	Bend	trans	-105.1	142.1	-177.7	-67.6	-170.5	-70.4	0	0	112.2	I58 I62 V350 I400 R401 I412	I58-M404 HydrophobicContact CG2-CE 4.08Å; I58-M404 HydrophobicContact CG2-SD 3.68Å; I62-M404 HydrophobicContact CD1-SD 3.87Å; I62-M404 HydrophobicContact CG1-SD 4.12Å; V350-M404 HydrophobicContact CG2-CG 4.14Å; I400-M404 HydrophobicContact CG2-CE 4.17Å; I400-M404 HydrophobicContact CG2-CG 4.45Å; I400-M404 HydrophobicContact CG2-SD 4.39Å; I400-M404 PolarHBondContact O-N 3.3Å; R401-M404 PolarHBondContact O-N 3.37Å; M404-I412 HydrophobicContact CE-CD1 3.47Å; M404-I412 VanDerWaalsContact CE-CD1 3.47Å
405	P	66.1	Low	76.7	Confident	28 Å²	28	38.3 Å²	38.3	18%	0.182	20%	0.195	C	C	.	.			trans	-57.5	158.7	173.9	-24.9	33.4	0	0	0	114	E407 Y408	P405-E407 PolarHBondContact O-N 2.94Å; P405-Y408 HydrophobicContact CB-CD2 4.08Å; P405-Y408 HydrophobicContact CB-CE2 4.39Å; P405-Y408 HydrophobicContact CG-CD2 4.18Å; P405-Y408 HydrophobicContact CG-CE2 4.39Å; P405-Y408 PolarHBondContact O-N 3.19Å
406	L	67.8	Low	76	Confident	114 Å²	114	38.4 Å²	38.4	60%	0.597	20%	0.196	S	C	*	.	G	3₁₀ helix	trans	-57.1	-32.1	-178	-58.4	-174.3	0	0	0	113.8	Y408 R409	L406-Y408 PolarHBondContact O-N 3.46Å; L406-R409 VanDerWaalsContact CD2-NE 3.25Å; L406-R409 VanDerWaalsContact CD2-NH1 3.29Å; L406-R409 WeakPolarHBondContact O-CG 3.43Å
407	E	67.8	Low	75.3	Confident	123 Å²	123	38.6 Å²	38.6	58%	0.575	20%	0.199	S	C	*	.	G	3₁₀ helix	trans	-69.6	-32.6	-174	-61.9	176.5	-178.4	0	0	112	P405	P405-E407 PolarHBondContact O-N 2.94Å
408	Y	70.8	Confident	74.5	Confident	38 Å²	38	46 Å²	46	15%	0.149	23%	0.233	C	C	.	.	G	3₁₀ helix	trans	-101.6	2.5	-175.8	-50.1	-69.2	0	0	0	113.9	E61 Q343 P405 L406	E61-Y408 VanDerWaalsContact CG-O 3.26Å; E61-Y408 WeakPolarHBondContact CG-O 3.26Å; Q343-Y408 HydrophobicContact CB-CE2 4.5Å; Q343-Y408 HydrophobicContact CG-CE2 4.16Å; Q343-Y408 VanDerWaalsContact CG-OH 3.25Å; Q343-Y408 WeakPolarHBondContact CG-OH 3.42Å; Q343-Y408 PolarHBondContact NE2-OH 3.04Å; Q343-Y408 PolarHBondContact OE1-OH 3.19Å; Q343-Y408 VanDerWaalsContact OE1-OH 3.06Å; P405-Y408 HydrophobicContact CB-CD2 4.08Å; P405-Y408 HydrophobicContact CB-CE2 4.39Å; P405-Y408 HydrophobicContact CG-CD2 4.18Å; P405-Y408 HydrophobicContact CG-CE2 4.39Å; P405-Y408 PolarHBondContact O-N 3.19Å; L406-Y408 PolarHBondContact O-N 3.46Å
409	R	73.9	Confident	73.9	Confident	76 Å²	76	46.8 Å²	46.8	29%	0.287	24%	0.237	S	C	.	.			trans	-101.9	2.7	-177.7	77.5	-177.5	-167.1	176.6	5.4	113.8	R401 L406 T413	R401-R409 HydrophobicContact CG-CB 4.44Å; L406-R409 VanDerWaalsContact CD2-NE 3.25Å; L406-R409 VanDerWaalsContact CD2-NH1 3.29Å; L406-R409 WeakPolarHBondContact O-CG 3.43Å; R409-T413 WeakPolarHBondContact O-CB 3.05Å; R409-T413 PolarHBondContact O-N 2.72Å; R409-T413 PolarHBondContact O-OG1 3.09Å
410	T	77.5	Confident	73.7	Confident	83 Å²	83	51.5 Å²	51.5	51%	0.509	26%	0.259	S	S	.	.	H	α-helix	trans	-63.3	-58.1	-171.5	45.9	0	0	0	0	112	I412 T413 E414	T410-I412 VanDerWaalsContact C-N 3.3Å; T410-I412 PolarHBondContact O-N 3.23Å; T410-T413 PolarHBondContact O-N 3.01Å; T410-T413 VanDerWaalsContact O-N 3.15Å; T410-E414 PolarHBondContact O-N 3.49Å
411	I	80.1	Confident	73.5	Confident	14 Å²	14	51.8 Å²	51.8	7%	0.072	26%	0.26	C	S	.	.	H	α-helix	trans	-60	-42.8	178.4	-70.9	172.7	0	0	0	110.8	E61 R71 Y72 W75 T413 E414 V415	E61-I411 WeakPolarHBondContact OE2-CD1 2.92Å; R71-I411 HydrophobicContact CB-CD1 4.22Å; Y72-I411 HydrophobicContact CD2-CG2 4.34Å; W75-I411 HydrophobicContact CG-CG2 4.25Å; I411-T413 VanDerWaalsContact C-N 3.33Å; I411-T413 PolarHBondContact O-N 3.33Å; I411-E414 PolarHBondContact O-N 2.83Å; I411-V415 HydrophobicContact CG2-CG2 4.14Å; I411-V415 WeakPolarHBondContact O-CB 3.45Å; I411-V415 WeakPolarHBondContact O-CG2 2.89Å; I411-V415 PolarHBondContact O-N 3.08Å
412	I	78.3	Confident	73.7	Confident	1 Å²	1	55 Å²	55	1%	0.005	28%	0.278	C	S	.	.	H	α-helix	trans	-63.2	-40.8	179.1	-62	175.1	0	0	0	110.9	I58 W75 R401 M404 T410 L416	I58-I412 HydrophobicContact CG1-CD1 4.19Å; W75-I412 HydrophobicContact CH2-CG1 4.41Å; W75-I412 HydrophobicContact CZ2-CD1 4.06Å; W75-I412 HydrophobicContact CZ2-CG1 3.87Å; R401-I412 HydrophobicContact CB-CG2 4.41Å; R401-I412 HydrophobicContact CG-CG2 4.21Å; M404-I412 HydrophobicContact CE-CD1 3.47Å; M404-I412 VanDerWaalsContact CE-CD1 3.47Å; T410-I412 VanDerWaalsContact C-N 3.3Å; T410-I412 PolarHBondContact O-N 3.23Å; I412-L416 HydrophobicContact CG2-CD1 3.42Å; I412-L416 VanDerWaalsContact CG2-CD1 3.42Å; I412-L416 HydrophobicContact CG2-CG 4.08Å; I412-L416 WeakPolarHBondContact O-CB 3.22Å; I412-L416 WeakPolarHBondContact O-CD1 3.34Å; I412-L416 WeakPolarHBondContact O-CG 3.5Å; I412-L416 PolarHBondContact O-N 3.13Å
413	T	80.1	Confident	74.5	Confident	43 Å²	43	54.3 Å²	54.3	26%	0.264	27%	0.274	S	S	.	.	H	α-helix	trans	-67.4	-40.9	177.8	-57.9	0	0	0	0	111.4	R401 R409 T410 I411 G417	R401-T413 PolarHBondContact NE-OG1 3.49Å; R401-T413 PolarHBondContact NH2-OG1 2.92Å; R409-T413 WeakPolarHBondContact O-CB 3.05Å; R409-T413 PolarHBondContact O-N 2.72Å; R409-T413 PolarHBondContact O-OG1 3.09Å; T410-T413 PolarHBondContact O-N 3.01Å; T410-T413 VanDerWaalsContact O-N 3.15Å; I411-T413 VanDerWaalsContact C-N 3.33Å; I411-T413 PolarHBondContact O-N 3.33Å; T413-G417 PolarHBondContact O-N 2.94Å
414	E	81.4	Confident	75.4	Confident	123 Å²	123	52.7 Å²	52.7	58%	0.575	26%	0.262	S	S	*	.	H	α-helix	trans	-67	-41.1	178.9	-168	-177	163.2	0	0	111.9	Y72 T410 I411	Y72-E414 HydrophobicContact CE2-CB 4.46Å; Y72-E414 HydrophobicContact CE2-CG 3.98Å; Y72-E414 WeakPolarHBondContact CE2-OE1 3.13Å; T410-E414 PolarHBondContact O-N 3.49Å; I411-E414 PolarHBondContact O-N 2.83Å
415	V	78.6	Confident	76.1	Confident	17 Å²	17	55 Å²	55	10%	0.103	27%	0.273	C	S	.	.	H	α-helix	trans	-76	-37.2	-178.1	173.1	0	0	0	0	112.1	Y72 W75 L79 I411 G417	Y72-V415 HydrophobicContact CD2-CG2 3.69Å; Y72-V415 HydrophobicContact CE2-CG2 3.65Å; W75-V415 HydrophobicContact CB-CG1 4.23Å; W75-V415 HydrophobicContact CB-CG2 4.03Å; L79-V415 HydrophobicContact CD1-CG1 3.3Å; I411-V415 HydrophobicContact CG2-CG2 4.14Å; I411-V415 WeakPolarHBondContact O-CB 3.45Å; I411-V415 WeakPolarHBondContact O-CG2 2.89Å; I411-V415 PolarHBondContact O-N 3.08Å; V415-G417 VanDerWaalsContact C-N 3.31Å
416	L	76.3	Confident	77.1	Confident	2 Å²	2	59.1 Å²	59.1	1%	0.01	29%	0.285	C	S	.	.	H	α-helix	trans	-76.7	-19.9	177.1	-66.5	176.4	0	0	0	112.7	L79 I147 L398 I412 L419 F421	L79-L416 HydrophobicContact CD1-CD2 4.2Å; I147-L416 HydrophobicContact CD1-CD2 3.22Å; I147-L416 HydrophobicContact CG1-CD2 4.4Å; L398-L416 HydrophobicContact CD2-CD1 3.84Å; L398-L416 HydrophobicContact CD2-CD2 3.7Å; L398-L416 HydrophobicContact CD2-CG 4.35Å; I412-L416 HydrophobicContact CG2-CD1 3.42Å; I412-L416 VanDerWaalsContact CG2-CD1 3.42Å; I412-L416 HydrophobicContact CG2-CG 4.08Å; I412-L416 WeakPolarHBondContact O-CB 3.22Å; I412-L416 WeakPolarHBondContact O-CD1 3.34Å; I412-L416 WeakPolarHBondContact O-CG 3.5Å; I412-L416 PolarHBondContact O-N 3.13Å; L416-L419 HydrophobicContact CB-CD1 4.2Å; L416-L419 WeakPolarHBondContact O-CD1 2.97Å; L416-L419 WeakPolarHBondContact O-CG 2.97Å; L416-F421 HydrophobicContact CB-CZ 3.96Å; L416-F421 HydrophobicContact CD1-CE1 3.9Å; L416-F421 HydrophobicContact CD1-CZ 3.98Å
417	G	74.2	Confident	78.2	Confident	8 Å²	8	56.8 Å²	56.8	8%	0.082	27%	0.268	C	S	.	.			trans	79.7	-169.5	-179.4	0	0	0	0	0	114.2	E144 T413 V415 L419	E144-G417 VanDerWaalsContact OE1-CA 3.28Å; E144-G417 WeakPolarHBondContact OE1-CA 3.33Å; T413-G417 PolarHBondContact O-N 2.94Å; V415-G417 VanDerWaalsContact C-N 3.31Å; G417-L419 PolarHBondContact O-N 2.86Å
418	E	68	Low	79.3	Confident	158 Å²	158	51.8 Å²	51.8	74%	0.738	24%	0.244	S	C	*	.	S	Bend	trans	-77.6	48.7	-179.8	-64.2	-171.9	162.1	0	0	112.7
419	L	71.9	Confident	80.3	Confident	17 Å²	17	51.1 Å²	51.1	9%	0.089	24%	0.243	C	C	.	.			trans	-67.1	140.9	176.3	-64.3	172.8	0	0	0	110.9	I147 L398 L416 G417 F421	I147-L419 HydrophobicContact CG2-CD1 3.95Å; L398-L419 HydrophobicContact CD2-CD1 4.07Å; L416-L419 HydrophobicContact CB-CD1 4.2Å; L416-L419 WeakPolarHBondContact O-CD1 2.97Å; L416-L419 WeakPolarHBondContact O-CG 2.97Å; G417-L419 PolarHBondContact O-N 2.86Å; L419-F421 HydrophobicContact CB-CD1 4.43Å; L419-F421 HydrophobicContact CB-CD2 4.16Å; L419-F421 HydrophobicContact CB-CE1 4.07Å; L419-F421 HydrophobicContact CB-CE2 3.78Å; L419-F421 HydrophobicContact CB-CG 4.47Å; L419-F421 HydrophobicContact CB-CZ 3.74Å; L419-F421 HydrophobicContact CD1-CE1 4.17Å; L419-F421 HydrophobicContact CD1-CZ 4.15Å; L419-F421 HydrophobicContact CG-CZ 4.4Å; L419-F421 WeakPolarHBondContact O-CD2 3.27Å; L419-F421 VanDerWaalsContact O-CE2 3.3Å; L419-F421 WeakPolarHBondContact O-CE2 3.04Å; L419-F421 PolarHBondContact O-N 3.04Å
420	Q	76.3	Confident	81.2	Confident	115 Å²	115	49.7 Å²	49.7	54%	0.537	24%	0.243	S	C	.	.			trans	-75.4	74.5	170.6	-65.9	-169.3	-3.5	0	0	110.4	P132 N422 F423	P132-Q420 PolarHBondContact O-OE1 2.61Å; Q420-N422 PolarHBondContact O-N 3.42Å; Q420-N422 VanDerWaalsContact O-N 3.09Å; Q420-F423 HydrophobicContact CB-CB 4.27Å; Q420-F423 VanDerWaalsContact O-CB 3.26Å; Q420-F423 WeakPolarHBondContact O-CB 3.4Å; Q420-F423 PolarHBondContact O-N 2.87Å
421	F	75.8	Confident	82.1	Confident	14 Å²	14	47 Å²	47	6%	0.061	23%	0.225	C	C	.	.	H	α-helix	trans	-56.9	-29.4	-176.3	-65.5	-81.8	0	0	0	114.5	L398 R401 M402 L416 L419 F423 Y424 H425	L398-F421 HydrophobicContact CD2-CE1 4.17Å; R401-F421 VanDerWaalsContact CZ-CE2 3.43Å; R401-F421 VanDerWaalsContact NH1-CG 3.25Å; M402-F421 HydrophobicContact CE-CB 3.2Å; M402-F421 HydrophobicContact CE-CG 4.13Å; L416-F421 HydrophobicContact CB-CZ 3.96Å; L416-F421 HydrophobicContact CD1-CE1 3.9Å; L416-F421 HydrophobicContact CD1-CZ 3.98Å; L419-F421 HydrophobicContact CB-CD1 4.43Å; L419-F421 HydrophobicContact CB-CD2 4.16Å; L419-F421 HydrophobicContact CB-CE1 4.07Å; L419-F421 HydrophobicContact CB-CE2 3.78Å; L419-F421 HydrophobicContact CB-CG 4.47Å; L419-F421 HydrophobicContact CB-CZ 3.74Å; L419-F421 HydrophobicContact CD1-CE1 4.17Å; L419-F421 HydrophobicContact CD1-CZ 4.15Å; L419-F421 HydrophobicContact CG-CZ 4.4Å; L419-F421 WeakPolarHBondContact O-CD2 3.27Å; L419-F421 VanDerWaalsContact O-CE2 3.3Å; L419-F421 WeakPolarHBondContact O-CE2 3.04Å; L419-F421 PolarHBondContact O-N 3.04Å; F421-F423 PolarHBondContact O-N 3.43Å; F421-Y424 PolarHBondContact O-N 2.82Å; F421-Y424 VanDerWaalsContact O-N 3.13Å; F421-H425 PolarHBondContact O-N 2.68Å
422	N	79.8	Confident	82.8	Confident	84 Å²	84	46.3 Å²	46.3	45%	0.449	22%	0.222	S	C	.	.	H	α-helix	trans	-60.3	-35.2	175.5	-61.8	-12.8	0	0	0	111.9	V315 Q420 Y424 H425 R426	V315-N422 HydrophobicContact CG1-CB 4.1Å; V315-N422 WeakPolarHBondContact CG1-OD1 3.47Å; V315-N422 HydrophobicContact CG2-CB 4.23Å; Q420-N422 PolarHBondContact O-N 3.42Å; Q420-N422 VanDerWaalsContact O-N 3.09Å; N422-Y424 VanDerWaalsContact C-N 3.35Å; N422-Y424 PolarHBondContact O-N 3.15Å; N422-H425 PolarHBondContact O-N 2.82Å; N422-R426 PolarHBondContact O-N 2.85Å; N422-R426 VanDerWaalsContact O-N 3.08Å
423	F	84.5	Confident	83.5	Confident	37 Å²	37	47.6 Å²	47.6	16%	0.162	23%	0.228	C	C	.	.	H	α-helix	trans	-61.2	-43.5	175.7	162.9	-93.9	0	0	0	110.9	F131 P132 V152 Q420 F421 H425 R426 W427	F131-F423 HydrophobicContact CB-CZ 4.17Å; F131-F423 HydrophobicContact CD1-CE1 4.18Å; F131-F423 AromaticContact CD1-CE2 3.69Å; F131-F423 HydrophobicContact CD1-CE2 3.69Å; F131-F423 AromaticContact CD1-CZ 3.2Å; F131-F423 HydrophobicContact CD1-CZ 3.2Å; F131-F423 HydrophobicContact CE1-CE2 4.3Å; F131-F423 AromaticContact CE1-CZ 3.73Å; F131-F423 HydrophobicContact CE1-CZ 3.73Å; F131-F423 HydrophobicContact CG-CE1 4.47Å; F131-F423 AromaticContact CG-CZ 3.88Å; F131-F423 HydrophobicContact CG-CZ 3.88Å; P132-F423 HydrophobicContact CG-CD2 3.98Å; P132-F423 HydrophobicContact CG-CG 4.31Å; V152-F423 HydrophobicContact CG2-CE1 3.92Å; Q420-F423 HydrophobicContact CB-CB 4.27Å; Q420-F423 VanDerWaalsContact O-CB 3.26Å; Q420-F423 WeakPolarHBondContact O-CB 3.4Å; Q420-F423 PolarHBondContact O-N 2.87Å; F421-F423 PolarHBondContact O-N 3.43Å; F423-H425 PolarHBondContact O-N 3.29Å; F423-R426 PolarHBondContact O-N 3.3Å; F423-W427 HydrophobicContact CE1-CB 4.43Å; F423-W427 HydrophobicContact CE2-CE3 4.29Å; F423-W427 HydrophobicContact CZ-CB 4.2Å; F423-W427 HydrophobicContact CZ-CD2 4.22Å; F423-W427 HydrophobicContact CZ-CE3 4.2Å; F423-W427 HydrophobicContact CZ-CG 4.24Å; F423-W427 WeakPolarHBondContact O-CB 3.09Å; F423-W427 PolarHBondContact O-N 2.9Å
424	Y	86.2	Confident	84.3	Confident	3 Å²	3	49.8 Å²	49.8	1%	0.012	24%	0.241	C	C	.	.	H	α-helix	trans	-64.8	-37.6	-179.7	-67.7	-84.5	0	0	0	113.1	S148 V152 V155 L398 F421 N422 F428	S148-Y424 VanDerWaalsContact C-OH 3.26Å; S148-Y424 WeakPolarHBondContact CA-OH 3.2Å; S148-Y424 WeakPolarHBondContact CB-OH 3.32Å; S148-Y424 PolarHBondContact O-OH 3.47Å; V152-Y424 HydrophobicContact CG2-CE1 3.85Å; V155-Y424 HydrophobicContact CG2-CD1 4.01Å; L398-Y424 HydrophobicContact CD1-CE1 4.47Å; F421-Y424 PolarHBondContact O-N 2.82Å; F421-Y424 VanDerWaalsContact O-N 3.13Å; N422-Y424 VanDerWaalsContact C-N 3.35Å; N422-Y424 PolarHBondContact O-N 3.15Å; Y424-F428 WeakPolarHBondContact O-CB 3.18Å; Y424-F428 PolarHBondContact O-N 3.05Å
425	H	84.2	Confident	85	Confident	57 Å²	57	44.3 Å²	44.3	26%	0.264	22%	0.217	S	C	.	.	H	α-helix	trans	-67.8	-45.3	175.2	-82.6	-77.3	0	0	0	112.2	M402 F421 N422 F423 W427 F428 D429	M402-H425 VanDerWaalsContact CB-NE2 3.26Å; M402-H425 WeakPolarHBondContact CB-NE2 3.21Å; M402-H425 WeakPolarHBondContact CG-NE2 3.34Å; F421-H425 PolarHBondContact O-N 2.68Å; N422-H425 PolarHBondContact O-N 2.82Å; F423-H425 PolarHBondContact O-N 3.29Å; H425-W427 VanDerWaalsContact C-N 3.3Å; H425-W427 PolarHBondContact O-N 2.95Å; H425-F428 WeakPolarHBondContact O-CB 3.26Å; H425-F428 PolarHBondContact O-N 3.49Å; H425-D429 PolarHBondContact O-N 3.24Å
426	R	87.1	Confident	85.7	Confident	115 Å²	115	43.5 Å²	43.5	43%	0.434	21%	0.212	S	C	.	.	H	α-helix	trans	-62.7	-41.7	175.6	-175.9	171.5	174	169.4	-3.8	111.2	D313 N422 F423 F428 D429 V430	D313-R426 IonicContact OD1-CZ 2.88Å; D313-R426 IonicContact OD1-NE 3.67Å; D313-R426 IonicContact OD1-NH1 3.6Å; D313-R426 PolarHBondContact OD1-NH1 2.95Å; D313-R426 IonicContact OD2-NH1 3.85Å; D313-R426 PolarHBondContact OD2-NH1 3.36Å; N422-R426 PolarHBondContact O-N 2.85Å; N422-R426 VanDerWaalsContact O-N 3.08Å; F423-R426 PolarHBondContact O-N 3.3Å; R426-F428 VanDerWaalsContact C-N 3.35Å; R426-D429 PolarHBondContact O-N 3.46Å; R426-V430 VanDerWaalsContact O-CG2 3.28Å; R426-V430 WeakPolarHBondContact O-CG2 3.3Å; R426-V430 PolarHBondContact O-N 3.17Å
427	W	90.2	Very high	86.5	Confident	64 Å²	64	47.9 Å²	47.9	24%	0.242	24%	0.235	C	C	.	.	H	α-helix	trans	-60.8	-44.3	175.2	-172.8	-105.8	0	0	0	111.6	F131 T156 F423 H425 V430 I431	F131-W427 HydrophobicContact CE1-CD2 4.42Å; F131-W427 HydrophobicContact CE1-CE3 4.09Å; F131-W427 AromaticContact CE1-CH2 3.72Å; F131-W427 HydrophobicContact CE1-CH2 3.72Å; F131-W427 HydrophobicContact CE1-CZ2 4.06Å; F131-W427 AromaticContact CE1-CZ3 3.74Å; F131-W427 HydrophobicContact CE1-CZ3 3.74Å; F131-W427 AromaticContact CZ-CH2 3.9Å; F131-W427 HydrophobicContact CZ-CH2 3.9Å; F131-W427 AromaticContact CZ-CZ2 3.94Å; F131-W427 HydrophobicContact CZ-CZ2 3.94Å; F131-W427 HydrophobicContact CZ-CZ3 4.38Å; T156-W427 PolarHBondContact OG1-NE1 3.4Å; F423-W427 HydrophobicContact CE1-CB 4.43Å; F423-W427 HydrophobicContact CE2-CE3 4.29Å; F423-W427 HydrophobicContact CZ-CB 4.2Å; F423-W427 HydrophobicContact CZ-CD2 4.22Å; F423-W427 HydrophobicContact CZ-CE3 4.2Å; F423-W427 HydrophobicContact CZ-CG 4.24Å; F423-W427 WeakPolarHBondContact O-CB 3.09Å; F423-W427 PolarHBondContact O-N 2.9Å; H425-W427 VanDerWaalsContact C-N 3.3Å; H425-W427 PolarHBondContact O-N 2.95Å; W427-V430 PolarHBondContact O-N 3.46Å; W427-I431 HydrophobicContact CD2-CG1 4.27Å; W427-I431 HydrophobicContact CH2-CD1 4.3Å; W427-I431 HydrophobicContact CZ2-CD1 3.9Å; W427-I431 HydrophobicContact CZ2-CG1 4.14Å; W427-I431 WeakPolarHBondContact O-CG1 3.29Å; W427-I431 PolarHBondContact O-N 2.8Å
428	F	91.1	Very high	87.5	Confident	18 Å²	18	50.5 Å²	50.5	8%	0.079	25%	0.252	C	S	.	.	H	α-helix	trans	-56.4	-52.2	173.4	179.5	-87.6	0	0	0	111.3	V155 M158 A159 L399 Y424 H425 R426 V430 I431 F432	V155-F428 HydrophobicContact CG1-CB 3.69Å; V155-F428 HydrophobicContact CG1-CD2 4.14Å; V155-F428 HydrophobicContact CG1-CG 4.43Å; M158-F428 HydrophobicContact CB-CE2 4.42Å; M158-F428 HydrophobicContact CG-CE2 4Å; M158-F428 HydrophobicContact SD-CE2 4.32Å; A159-F428 HydrophobicContact CB-CD2 3.66Å; A159-F428 HydrophobicContact CB-CE2 3.87Å; A159-F428 HydrophobicContact CB-CG 4.2Å; A159-F428 WeakPolarHBondContact CB-O 3.23Å; L399-F428 HydrophobicContact CD1-CD2 4.09Å; Y424-F428 WeakPolarHBondContact O-CB 3.18Å; Y424-F428 PolarHBondContact O-N 3.05Å; H425-F428 WeakPolarHBondContact O-CB 3.26Å; H425-F428 PolarHBondContact O-N 3.49Å; R426-F428 VanDerWaalsContact C-N 3.35Å; F428-V430 VanDerWaalsContact C-N 3.34Å; F428-V430 PolarHBondContact O-N 2.85Å; F428-I431 PolarHBondContact O-N 2.87Å; F428-F432 HydrophobicContact CD1-CB 4.44Å; F428-F432 HydrophobicContact CE1-CB 4.18Å; F428-F432 HydrophobicContact CE1-CG 4.39Å; F428-F432 WeakPolarHBondContact O-CB 3.29Å; F428-F432 PolarHBondContact O-N 3Å
429	D	91.4	Very high	88.7	Confident	24 Å²	24	43.6 Å²	43.6	13%	0.128	22%	0.221	C	C	.	.	H	α-helix	trans	-61.5	-41.3	-177.2	-77.1	-10.5	0	0	0	111.7	A306 N309 I310 H425 R426 L433	A306-D429 HydrophobicContact CB-CB 4.2Å; N309-D429 WeakPolarHBondContact CB-OD2 3.43Å; N309-D429 PolarHBondContact ND2-OD2 3Å; I310-D429 HydrophobicContact CD1-CB 4.32Å; I310-D429 HydrophobicContact CG1-CB 4.2Å; H425-D429 PolarHBondContact O-N 3.24Å; R426-D429 PolarHBondContact O-N 3.46Å; D429-L433 WeakPolarHBondContact O-CB 3.49Å; D429-L433 PolarHBondContact O-N 2.8Å
430	V	93.3	Very high	89.6	Confident	46 Å²	46	46.6 Å²	46.6	28%	0.279	24%	0.236	S	C	.	.	H	α-helix	trans	-62.3	-53.2	177.1	170.8	0	0	0	0	111.2	I310 R426 W427 F428 F432 L433 V434	I310-V430 HydrophobicContact CD1-CB 4.45Å; I310-V430 HydrophobicContact CD1-CG2 3.91Å; I310-V430 HydrophobicContact CG1-CG2 3.88Å; I310-V430 HydrophobicContact CG2-CG2 4.46Å; R426-V430 VanDerWaalsContact O-CG2 3.28Å; R426-V430 WeakPolarHBondContact O-CG2 3.3Å; R426-V430 PolarHBondContact O-N 3.17Å; W427-V430 PolarHBondContact O-N 3.46Å; F428-V430 VanDerWaalsContact C-N 3.34Å; F428-V430 PolarHBondContact O-N 2.85Å; V430-F432 VanDerWaalsContact C-N 3.32Å; V430-F432 PolarHBondContact O-N 3.32Å; V430-L433 PolarHBondContact O-N 3.18Å; V430-V434 WeakPolarHBondContact O-CG2 3.44Å; V430-V434 PolarHBondContact O-N 3.04Å
431	I	95	Very high	90.4	Very high	27 Å²	27	45.9 Å²	45.9	14%	0.138	24%	0.236	C	C	.	.	H	α-helix	trans	-66.6	-37.3	-178.3	-61.6	-60.6	0	0	0	111	T156 A159 L160 W427 F428 V434 S435	T156-I431 HydrophobicContact CG2-CG1 4.45Å; T156-I431 HydrophobicContact CG2-CG2 4.07Å; A159-I431 HydrophobicContact CB-CB 3.7Å; A159-I431 HydrophobicContact CB-CG2 3.63Å; L160-I431 HydrophobicContact CD2-CG2 3.74Å; L160-I431 HydrophobicContact CG-CG2 3.8Å; W427-I431 HydrophobicContact CD2-CG1 4.27Å; W427-I431 HydrophobicContact CH2-CD1 4.3Å; W427-I431 HydrophobicContact CZ2-CD1 3.9Å; W427-I431 HydrophobicContact CZ2-CG1 4.14Å; W427-I431 WeakPolarHBondContact O-CG1 3.29Å; W427-I431 PolarHBondContact O-N 2.8Å; F428-I431 PolarHBondContact O-N 2.87Å; I431-V434 PolarHBondContact O-N 3.46Å; I431-S435 VanDerWaalsContact O-CB 3.27Å; I431-S435 WeakPolarHBondContact O-CB 3.33Å; I431-S435 PolarHBondContact O-N 3.43Å
432	F	94.6	Very high	91.2	Very high	0 Å²	0	52 Å²	52	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-59.6	-47.9	175.3	169.1	-95.4	0	0	0	110.9	A159 S162 A166 K302 I303 A306 F428 V430 S435 A436	A159-F432 HydrophobicContact CB-CB 4.31Å; S162-F432 WeakPolarHBondContact O-CE2 3.2Å; A166-F432 HydrophobicContact CB-CE2 3.97Å; A166-F432 HydrophobicContact CB-CZ 3.97Å; K302-F432 HydrophobicContact CB-CZ 4.41Å; K302-F432 HydrophobicContact CD-CE1 4.3Å; K302-F432 HydrophobicContact CD-CE2 4.06Å; K302-F432 HydrophobicContact CD-CZ 3.7Å; K302-F432 HydrophobicContact CG-CE1 3.98Å; K302-F432 HydrophobicContact CG-CZ 3.82Å; I303-F432 HydrophobicContact CG1-CE1 3.98Å; I303-F432 HydrophobicContact CG1-CZ 4.19Å; A306-F432 HydrophobicContact CB-CD1 3.98Å; A306-F432 HydrophobicContact CB-CE1 4.27Å; F428-F432 HydrophobicContact CD1-CB 4.44Å; F428-F432 HydrophobicContact CE1-CB 4.18Å; F428-F432 HydrophobicContact CE1-CG 4.39Å; F428-F432 WeakPolarHBondContact O-CB 3.29Å; F428-F432 PolarHBondContact O-N 3Å; V430-F432 VanDerWaalsContact C-N 3.32Å; V430-F432 PolarHBondContact O-N 3.32Å; F432-S435 PolarHBondContact O-N 3.33Å; F432-A436 WeakPolarHBondContact O-CB 3.39Å; F432-A436 PolarHBondContact O-N 3.39Å
433	L	94.6	Very high	91.5	Very high	27 Å²	27	49.4 Å²	49.4	14%	0.141	25%	0.249	C	C	.	.	H	α-helix	trans	-64.3	-46	179.8	-175.6	64	0	0	0	111.4	I303 I310 D429 V430 S435 A436 L437	I303-L433 HydrophobicContact CG2-CD1 3.85Å; I310-L433 HydrophobicContact CD1-CB 4.25Å; I310-L433 HydrophobicContact CD1-CD2 3.77Å; D429-L433 WeakPolarHBondContact O-CB 3.49Å; D429-L433 PolarHBondContact O-N 2.8Å; V430-L433 PolarHBondContact O-N 3.18Å; L433-S435 VanDerWaalsContact C-N 3.3Å; L433-S435 PolarHBondContact O-N 3.24Å; L433-A436 PolarHBondContact O-N 3.33Å; L433-L437 HydrophobicContact CD1-CD1 4.15Å; L433-L437 HydrophobicContact CD1-CG 4.21Å; L433-L437 HydrophobicContact CG-CD1 3.98Å; L433-L437 HydrophobicContact CG-CG 4.41Å; L433-L437 WeakPolarHBondContact O-CB 3.31Å; L433-L437 VanDerWaalsContact O-CG 3.3Å; L433-L437 WeakPolarHBondContact O-CG 3.44Å; L433-L437 PolarHBondContact O-N 3.44Å
434	V	95.9	Very high	91.6	Very high	89 Å²	89	55 Å²	55	54%	0.539	27%	0.27	S	S	.	.	H	α-helix	trans	-58.9	-43.5	176.3	171.7	0	0	0	0	111	V430 I431 S438	V430-V434 WeakPolarHBondContact O-CG2 3.44Å; V430-V434 PolarHBondContact O-N 3.04Å; I431-V434 PolarHBondContact O-N 3.46Å; V434-S438 WeakPolarHBondContact O-CB 3.3Å; V434-S438 PolarHBondContact O-N 3.48Å; V434-S438 PolarHBondContact O-OG 2.84Å; V434-S438 VanDerWaalsContact O-OG 3.05Å
435	S	95.6	Very high	91.7	Very high	8 Å²	8	59 Å²	59	6%	0.056	29%	0.29	C	S	.	.	H	α-helix	trans	-67.1	-40.2	178	179.1	0	0	0	0	113.3	L160 F164 I431 F432 L433 S438 S439	L160-S435 PolarHBondContact O-OG 3Å; F164-S435 PolarHBondContact N-OG 3.06Å; I431-S435 VanDerWaalsContact O-CB 3.27Å; I431-S435 WeakPolarHBondContact O-CB 3.33Å; I431-S435 PolarHBondContact O-N 3.43Å; F432-S435 PolarHBondContact O-N 3.33Å; L433-S435 VanDerWaalsContact C-N 3.3Å; L433-S435 PolarHBondContact O-N 3.24Å; S435-S438 PolarHBondContact O-OG 3.2Å; S435-S438 VanDerWaalsContact O-OG 3.04Å; S435-S439 VanDerWaalsContact O-CB 3.3Å; S435-S439 WeakPolarHBondContact O-CB 3.45Å; S435-S439 PolarHBondContact O-N 3.41Å; S435-S439 PolarHBondContact O-OG 3.41Å
436	A	93.1	Very high	91.6	Very high	0 Å²	0	58.1 Å²	58.1	0%	0	29%	0.293	C	S	.	.	H	α-helix	trans	-66.1	-47.8	176.9	0	0	0	0	0	110.9	V167 I303 F432 L433 S438 S439 I440	V167-A436 HydrophobicContact CG2-CB 4.12Å; V167-A436 WeakPolarHBondContact CG2-O 3.37Å; I303-A436 HydrophobicContact CD1-CB 4.03Å; I303-A436 HydrophobicContact CG1-CB 4.17Å; F432-A436 WeakPolarHBondContact O-CB 3.39Å; F432-A436 PolarHBondContact O-N 3.39Å; L433-A436 PolarHBondContact O-N 3.33Å; A436-S438 PolarHBondContact O-N 3.34Å; A436-S439 PolarHBondContact O-N 2.91Å; A436-I440 VanDerWaalsContact O-CG1 3.31Å; A436-I440 WeakPolarHBondContact O-CG1 3.41Å; A436-I440 PolarHBondContact O-N 2.91Å
437	L	94.8	Very high	91.2	Very high	94 Å²	94	56.5 Å²	56.5	49%	0.492	29%	0.291	S	S	.	.	H	α-helix	trans	-63.7	-41.8	179.3	-68.3	175.4	0	0	0	112.3	L433 S439 I440 L441	L433-L437 HydrophobicContact CD1-CD1 4.15Å; L433-L437 HydrophobicContact CD1-CG 4.21Å; L433-L437 HydrophobicContact CG-CD1 3.98Å; L433-L437 HydrophobicContact CG-CG 4.41Å; L433-L437 WeakPolarHBondContact O-CB 3.31Å; L433-L437 VanDerWaalsContact O-CG 3.3Å; L433-L437 WeakPolarHBondContact O-CG 3.44Å; L433-L437 PolarHBondContact O-N 3.44Å; L437-S439 VanDerWaalsContact C-N 3.33Å; L437-S439 PolarHBondContact O-N 3.29Å; L437-I440 PolarHBondContact O-N 2.87Å; L437-L441 WeakPolarHBondContact O-CB 3.32Å; L437-L441 PolarHBondContact O-N 2.93Å
438	S	94.4	Very high	90.5	Very high	64 Å²	64	61.1 Å²	61.1	45%	0.448	31%	0.312	S	S	.	.	H	α-helix	trans	-66.1	-35.7	175.8	66.2	0	0	0	0	112.3	V434 S435 A436 L441 F442	V434-S438 WeakPolarHBondContact O-CB 3.3Å; V434-S438 PolarHBondContact O-N 3.48Å; V434-S438 PolarHBondContact O-OG 2.84Å; V434-S438 VanDerWaalsContact O-OG 3.05Å; S435-S438 PolarHBondContact O-OG 3.2Å; S435-S438 VanDerWaalsContact O-OG 3.04Å; A436-S438 PolarHBondContact O-N 3.34Å; S438-L441 PolarHBondContact O-N 3.4Å; S438-F442 WeakPolarHBondContact O-CB 3.24Å; S438-F442 PolarHBondContact O-N 2.73Å
439	S	92.4	Very high	89.3	Confident	12 Å²	12	68 Å²	68	8%	0.084	34%	0.344	C	S	.	.	H	α-helix	trans	-67.9	-40	174.8	-58.6	0	0	0	0	112.1	S435 A436 L437 F442 L443	S435-S439 VanDerWaalsContact O-CB 3.3Å; S435-S439 WeakPolarHBondContact O-CB 3.45Å; S435-S439 PolarHBondContact O-N 3.41Å; S435-S439 PolarHBondContact O-OG 3.41Å; A436-S439 PolarHBondContact O-N 2.91Å; L437-S439 VanDerWaalsContact C-N 3.33Å; L437-S439 PolarHBondContact O-N 3.29Å; S439-F442 PolarHBondContact O-N 2.73Å; S439-L443 WeakPolarHBondContact O-CG 3.49Å; S439-L443 PolarHBondContact O-N 3.16Å
440	I	92.3	Very high	87.7	Confident	80 Å²	80	68.4 Å²	68.4	41%	0.41	35%	0.352	S	S	.	.	H	α-helix	trans	-61.6	-47.7	173.6	-68.9	163.8	0	0	0	109.9	V167 A436 L437 F442 L443 Y444	V167-I440 HydrophobicContact CB-CG1 4.39Å; V167-I440 HydrophobicContact CG1-CG1 3.72Å; V167-I440 HydrophobicContact CG2-CD1 4.18Å; V167-I440 HydrophobicContact CG2-CG1 3.71Å; A436-I440 VanDerWaalsContact O-CG1 3.31Å; A436-I440 WeakPolarHBondContact O-CG1 3.41Å; A436-I440 PolarHBondContact O-N 2.91Å; L437-I440 PolarHBondContact O-N 2.87Å; I440-F442 VanDerWaalsContact C-N 3.34Å; I440-F442 PolarHBondContact O-N 2.8Å; I440-L443 PolarHBondContact O-N 3.43Å; I440-Y444 VanDerWaalsContact O-CB 3.31Å; I440-Y444 WeakPolarHBondContact O-CB 3.36Å; I440-Y444 PolarHBondContact O-N 3.27Å
441	L	92.6	Very high	85.6	Confident	101 Å²	101	70 Å²	70	53%	0.529	36%	0.363	S	S	.	.	H	α-helix	trans	-60.2	-44.6	177.6	179.4	63.6	0	0	0	111.6	L437 S438 Y444 L445	L437-L441 WeakPolarHBondContact O-CB 3.32Å; L437-L441 PolarHBondContact O-N 2.93Å; S438-L441 PolarHBondContact O-N 3.4Å; L441-Y444 PolarHBondContact O-N 2.89Å; L441-L445 HydrophobicContact CD1-CD1 4.32Å; L441-L445 HydrophobicContact CD1-CG 4.32Å; L441-L445 HydrophobicContact CG-CD1 4.22Å; L441-L445 WeakPolarHBondContact O-CG 3.28Å; L441-L445 PolarHBondContact O-N 3.26Å
442	F	91.3	Very high	83.2	Confident	141 Å²	141	75.9 Å²	75.9	62%	0.618	39%	0.39	S	S	*	.	H	α-helix	trans	-60.1	-48.8	177.8	176.8	-97	0	0	0	111.8	S438 S439 I440 Y444 L445 A446	S438-F442 WeakPolarHBondContact O-CB 3.24Å; S438-F442 PolarHBondContact O-N 2.73Å; S439-F442 PolarHBondContact O-N 2.73Å; I440-F442 VanDerWaalsContact C-N 3.34Å; I440-F442 PolarHBondContact O-N 2.8Å; F442-Y444 VanDerWaalsContact C-N 3.33Å; F442-Y444 PolarHBondContact O-N 3.04Å; F442-L445 PolarHBondContact O-N 3.26Å; F442-A446 WeakPolarHBondContact O-CB 3.42Å; F442-A446 PolarHBondContact O-N 3.21Å
443	L	86.9	Confident	80.7	Confident	31 Å²	31	81.9 Å²	81.9	16%	0.162	42%	0.416	C	S	.	.	H	α-helix	trans	-64.5	-38.3	177.5	-71.1	-179.2	0	0	0	112.2	V167 Y171 S439 I440 A446 H447	V167-L443 HydrophobicContact CG1-CD1 3.66Å; Y171-L443 HydrophobicContact CD1-CD1 4.11Å; Y171-L443 HydrophobicContact CD1-CD2 3.97Å; Y171-L443 HydrophobicContact CD2-CD1 3.96Å; Y171-L443 HydrophobicContact CE1-CD2 3.84Å; Y171-L443 HydrophobicContact CE2-CD2 4.44Å; Y171-L443 HydrophobicContact CG-CD1 3.71Å; Y171-L443 HydrophobicContact CG-CD2 4.33Å; S439-L443 WeakPolarHBondContact O-CG 3.49Å; S439-L443 PolarHBondContact O-N 3.16Å; I440-L443 PolarHBondContact O-N 3.43Å; L443-A446 PolarHBondContact O-N 3.29Å; L443-H447 WeakPolarHBondContact O-CB 3.47Å; L443-H447 PolarHBondContact O-N 2.95Å
444	Y	86.8	Confident	77.9	Confident	154 Å²	154	89.5 Å²	89.5	60%	0.604	45%	0.451	S	S	*	.	H	α-helix	trans	-61.5	-45	175.9	177.1	-102.3	0	0	0	111.9	I440 L441 F442 H447 K448	I440-Y444 VanDerWaalsContact O-CB 3.31Å; I440-Y444 WeakPolarHBondContact O-CB 3.36Å; I440-Y444 PolarHBondContact O-N 3.27Å; L441-Y444 PolarHBondContact O-N 2.89Å; F442-Y444 VanDerWaalsContact C-N 3.33Å; F442-Y444 PolarHBondContact O-N 3.04Å; Y444-H447 PolarHBondContact O-N 2.87Å; Y444-K448 PolarHBondContact O-N 3.14Å; Y444-K448 VanDerWaalsContact O-N 3.08Å
445	L	88.2	Confident	75.1	Confident	86 Å²	86	94 Å²	94	45%	0.45	47%	0.468	S	S	.	.	H	α-helix	trans	-66.2	-41.6	175.9	-68.5	175.1	0	0	0	112	L441 F442 H447 K448 Q449	L441-L445 HydrophobicContact CD1-CD1 4.32Å; L441-L445 HydrophobicContact CD1-CG 4.32Å; L441-L445 HydrophobicContact CG-CD1 4.22Å; L441-L445 WeakPolarHBondContact O-CG 3.28Å; L441-L445 PolarHBondContact O-N 3.26Å; F442-L445 PolarHBondContact O-N 3.26Å; L445-H447 VanDerWaalsContact C-N 3.33Å; L445-H447 PolarHBondContact O-N 3.25Å; L445-K448 PolarHBondContact O-N 2.93Å; L445-Q449 WeakPolarHBondContact O-CG 3.37Å; L445-Q449 PolarHBondContact O-N 3.09Å; L445-Q449 VanDerWaalsContact O-N 3.12Å
446	A	82.9	Confident	71.8	Confident	39 Å²	39	97.6 Å²	97.6	32%	0.322	50%	0.498	S	S	.	.	H	α-helix	trans	-62.6	-40.3	176.9	0	0	0	0	0	111.7	F442 L443 Q449 A450	F442-A446 WeakPolarHBondContact O-CB 3.42Å; F442-A446 PolarHBondContact O-N 3.21Å; L443-A446 PolarHBondContact O-N 3.29Å; A446-Q449 PolarHBondContact O-N 2.62Å; A446-A450 PolarHBondContact O-N 2.87Å; A446-A450 VanDerWaalsContact O-N 3.16Å
447	H	77.4	Confident	69.1	Low	82 Å²	82	107.2 Å²	107.2	38%	0.38	56%	0.561	S	S	.	*	H	α-helix	trans	-68.1	-37.6	177.8	-152.4	73.2	0	0	0	112.1	L443 Y444 L445 Q449 A450	L443-H447 WeakPolarHBondContact O-CB 3.47Å; L443-H447 PolarHBondContact O-N 2.95Å; Y444-H447 PolarHBondContact O-N 2.87Å; L445-H447 VanDerWaalsContact C-N 3.33Å; L445-H447 PolarHBondContact O-N 3.25Å; H447-Q449 VanDerWaalsContact C-N 3.29Å; H447-Q449 PolarHBondContact O-N 3.16Å; H447-A450 PolarHBondContact O-N 3.05Å
448	K	76.8	Confident	67.8	Low	160 Å²	160	107.9 Å²	107.9	70%	0.696	57%	0.565	S	S	*	*	H	α-helix	trans	-66.4	-29.5	175.6	-170	178.2	180	-179	0	113.2	Y444 L445	Y444-K448 PolarHBondContact O-N 3.14Å; Y444-K448 VanDerWaalsContact O-N 3.08Å; L445-K448 PolarHBondContact O-N 2.93Å
449	Q	65.1	Low	66.4	Low	162 Å²	162	110.2 Å²	110.2	76%	0.757	57%	0.571	S	S	*	*	H	α-helix	trans	-82.1	-23.9	178.3	-73.7	179.6	-8.6	0	0	113.1	L445 A446 H447 P451	L445-Q449 WeakPolarHBondContact O-CG 3.37Å; L445-Q449 PolarHBondContact O-N 3.09Å; L445-Q449 VanDerWaalsContact O-N 3.12Å; A446-Q449 PolarHBondContact O-N 2.62Å; H447-Q449 VanDerWaalsContact C-N 3.29Å; H447-Q449 PolarHBondContact O-N 3.16Å; Q449-P451 WeakPolarHBondContact O-CD 3.46Å
450	A	57.4	Low	65	Low	34 Å²	34	115.7 Å²	115.7	28%	0.281	60%	0.598	S	S	.	*	S	Bend	trans	-64.4	119.1	166.2	0	0	0	0	0	106.9	A446 H447 E452	A446-A450 PolarHBondContact O-N 2.87Å; A446-A450 VanDerWaalsContact O-N 3.16Å; H447-A450 PolarHBondContact O-N 3.05Å; A450-E452 VanDerWaalsContact C-N 3.31Å; A450-E452 PolarHBondContact O-N 3.38Å
451	P	49.1	Very low	63.4	Low	79 Å²	79	117.8 Å²	117.8	51%	0.513	61%	0.609	S	S	.	*			trans	-63.2	99	179.4	24.1	-30.5	0	0	0	107.6	R179 Q449 K453	R179-P451 PolarHBondContact NH2-O 2.95Å; Q449-P451 WeakPolarHBondContact O-CD 3.46Å; P451-K453 VanDerWaalsContact C-N 3.29Å; P451-K453 PolarHBondContact O-N 3.06Å
452	E	44.8	Very low	61.5	Low	151 Å²	151	118.8 Å²	118.8	71%	0.706	61%	0.614	S	S	*	*			trans	-53.7	106.4	156.7	-83.2	-172.7	152.1	0	0	104.8	A450 Q454	A450-E452 VanDerWaalsContact C-N 3.31Å; A450-E452 PolarHBondContact O-N 3.38Å; E452-Q454 PolarHBondContact O-N 3.15Å
453	K	42.3	Very low	59.6	Low	125 Å²	125	117.3 Å²	117.3	54%	0.543	61%	0.613	S	S	.	*			trans	-47	122.5	159.8	-79.9	178.6	167.7	-171.6	0	105.6	D185 P451 M455	D185-K453 IonicContact OD1-NZ 2.75Å; D185-K453 PolarHBondContact OD1-NZ 2.88Å; D185-K453 IonicContact OD2-NZ 3.9Å; D185-K453 PolarHBondContact OD2-NZ 3.24Å; P451-K453 VanDerWaalsContact C-N 3.29Å; P451-K453 PolarHBondContact O-N 3.06Å; K453-M455 PolarHBondContact O-N 3.44Å
454	Q	35.3	Very low	57.6	Low	188 Å²	188	123.5 Å²	123.5	88%	0.879	65%	0.646	S	S	*	*			trans	-33.4	105.7	163.9	-68.3	168.5	-29.1	0	0	108.2	E452 A456	E452-Q454 PolarHBondContact O-N 3.15Å; Q454-A456 PolarHBondContact O-N 3.05Å
455	M	36.4	Very low	55.4	Low	182 Å²	182	121.2 Å²	121.2	90%	0.897	65%	0.649	S	S	*	*			trans	-62.8	96.2	157.4	-73.4	-178.8	-178	0	0	103.9	K453	K453-M455 PolarHBondContact O-N 3.44Å
456	A	28.2	Very low	52.6	Low	84 Å²	84	124.1 Å²	124.1	69%	0.694	67%	0.665	S	S	*	*			trans	-64.7	137.8	159.6	0	0	0	0	0	106.8	Q454	Q454-A456 PolarHBondContact O-N 3.05Å
457	P	35.7	Very low	49.9	Very low	203 Å²	203	131.8 Å²	131.8	100%	1.318	70%	0.697	S	S	*	*			trans	-61.4	0	-171.4	25.2	-34.6	0	0	0	114.1

Retrieved 457 of 457 residues in 457.4 ms (Link to these results)

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