X5DNN3_HUMAN Loading...

G protein-coupled receptor 89B isoform D

AlphaFold DB , UniProt , Accession X5DNN3, Species HUMAN (Homo sapiens, Human), Gene GPR89B, Length 432 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	58.5	Low	87.6	Confident	193 Å²	193	76 Å²	76	95%	0.951	40%	0.403	S	S	*	.				0	-57.7	0	-69.4	-58.3	-149.2	0	0	112.3	F3 L4 I5	M1-F3 PolarHBondContact O-N 3.37Å; M1-L4 PolarHBondContact O-N 2.8Å; M1-I5 PolarHBondContact O-N 3.22Å
2	S	80.8	Confident	88.1	Confident	40 Å²	40	76.1 Å²	76.1	28%	0.28	41%	0.409	S	S	.	.	H	α-helix	trans	-60.8	-41.1	-176.9	159.3	0	0	0	0	114.8	L4 I5 D6 N67	S2-L4 VanDerWaalsContact C-N 3.3Å; S2-L4 PolarHBondContact O-N 2.63Å; S2-I5 PolarHBondContact O-N 3.07Å; S2-D6 WeakPolarHBondContact O-CB 3.45Å; S2-D6 PolarHBondContact O-N 3.39Å; S2-D6 PolarHBondContact OG-OD2 3.07Å; S2-N67 WeakPolarHBondContact CB-ND2 3.47Å; S2-N67 VanDerWaalsContact OG-CG 3.24Å; S2-N67 PolarHBondContact OG-ND2 2.98Å
3	F	89.4	Confident	88.5	Confident	93 Å²	93	70.9 Å²	70.9	41%	0.408	38%	0.382	S	S	.	.	H	α-helix	trans	-60.6	-36.3	179.7	-178.2	-100.1	0	0	0	113.9	M1 S7 F73	M1-F3 PolarHBondContact O-N 3.37Å; F3-S7 VanDerWaalsContact O-CB 3.26Å; F3-S7 WeakPolarHBondContact O-CB 3.38Å; F3-S7 PolarHBondContact O-N 3.36Å; F3-S7 PolarHBondContact O-OG 3.07Å; F3-F73 HydrophobicContact CE2-CB 4.25Å; F3-F73 AromaticContact CE2-CD1 3.74Å; F3-F73 HydrophobicContact CE2-CD1 3.74Å; F3-F73 HydrophobicContact CE2-CE1 4.36Å; F3-F73 HydrophobicContact CE2-CG 4.09Å; F3-F73 AromaticContact CZ-CD1 3.6Å; F3-F73 HydrophobicContact CZ-CD1 3.6Å; F3-F73 AromaticContact CZ-CE1 3.75Å; F3-F73 HydrophobicContact CZ-CE1 3.75Å; F3-F73 HydrophobicContact CZ-CG 4.17Å; F3-F73 HydrophobicContact CZ-CZ 4.43Å
4	L	88.9	Confident	88.9	Confident	125 Å²	125	68.1 Å²	68.1	65%	0.654	37%	0.365	S	S	*	.	H	α-helix	trans	-72	-37.8	178.7	-69.6	174.8	0	0	0	111.8	M1 S2 S8	M1-L4 PolarHBondContact O-N 2.8Å; S2-L4 VanDerWaalsContact C-N 3.3Å; S2-L4 PolarHBondContact O-N 2.63Å; L4-S8 WeakPolarHBondContact O-CB 3.49Å; L4-S8 PolarHBondContact O-N 2.89Å
5	I	90.7	Very high	89.2	Confident	103 Å²	103	71.1 Å²	71.1	53%	0.528	38%	0.379	S	S	.	.	H	α-helix	trans	-65.8	-47.7	175	-63.4	167.7	0	0	0	109.3	M1 S2 S7 S8 I9	M1-I5 PolarHBondContact O-N 3.22Å; S2-I5 PolarHBondContact O-N 3.07Å; I5-S7 VanDerWaalsContact C-N 3.33Å; I5-S7 PolarHBondContact O-N 2.95Å; I5-S8 WeakPolarHBondContact O-CB 3.32Å; I5-S8 PolarHBondContact O-N 3.21Å; I5-S8 VanDerWaalsContact O-N 3.09Å; I5-I9 HydrophobicContact CG2-CD1 4.18Å; I5-I9 WeakPolarHBondContact O-CG1 3.24Å; I5-I9 PolarHBondContact O-N 3.36Å
6	D	91.5	Very high	89.5	Confident	12 Å²	12	74 Å²	74	6%	0.064	39%	0.394	C	S	.	.	H	α-helix	trans	-59.1	-45.3	177.1	-68.3	2.3	0	0	0	111.1	S2 S8 I9 M10 L66 N67 S70	S2-D6 WeakPolarHBondContact O-CB 3.45Å; S2-D6 PolarHBondContact O-N 3.39Å; S2-D6 PolarHBondContact OG-OD2 3.07Å; D6-S8 VanDerWaalsContact C-N 3.31Å; D6-S8 PolarHBondContact O-N 3.12Å; D6-I9 PolarHBondContact O-N 3.06Å; D6-M10 WeakPolarHBondContact O-CG 3.4Å; D6-M10 PolarHBondContact O-N 3.37Å; D6-L66 HydrophobicContact CB-CB 4.46Å; D6-L66 HydrophobicContact CB-CD2 3.68Å; D6-N67 PolarHBondContact OD2-N 3.14Å; D6-S70 WeakPolarHBondContact CB-OG 3.32Å; D6-S70 WeakPolarHBondContact OD2-CB 3.39Å; D6-S70 PolarHBondContact OD2-OG 3.04Å
7	S	92.4	Very high	89.6	Confident	18 Å²	18	72.9 Å²	72.9	13%	0.126	39%	0.385	C	S	.	.	H	α-helix	trans	-62.4	-38.5	175	-66.3	0	0	0	0	112.1	F3 I5 M10 I11	F3-S7 VanDerWaalsContact O-CB 3.26Å; F3-S7 WeakPolarHBondContact O-CB 3.38Å; F3-S7 PolarHBondContact O-N 3.36Å; F3-S7 PolarHBondContact O-OG 3.07Å; I5-S7 VanDerWaalsContact C-N 3.33Å; I5-S7 PolarHBondContact O-N 2.95Å; S7-M10 PolarHBondContact O-N 3.45Å; S7-I11 WeakPolarHBondContact O-CB 3.2Å; S7-I11 WeakPolarHBondContact O-CD1 3.26Å; S7-I11 VanDerWaalsContact O-CG1 3.25Å; S7-I11 WeakPolarHBondContact O-CG1 3.38Å; S7-I11 PolarHBondContact O-N 3.46Å
8	S	92.5	Very high	89.8	Confident	69 Å²	69	72.4 Å²	72.4	48%	0.483	38%	0.379	S	S	.	.	H	α-helix	trans	-63.4	-43.6	176.3	-172.2	0	0	0	0	111.1	L4 I5 D6 I11 T12	L4-S8 WeakPolarHBondContact O-CB 3.49Å; L4-S8 PolarHBondContact O-N 2.89Å; I5-S8 WeakPolarHBondContact O-CB 3.32Å; I5-S8 PolarHBondContact O-N 3.21Å; I5-S8 VanDerWaalsContact O-N 3.09Å; D6-S8 VanDerWaalsContact C-N 3.31Å; D6-S8 PolarHBondContact O-N 3.12Å; S8-I11 PolarHBondContact O-N 2.89Å; S8-T12 WeakPolarHBondContact O-CB 3.49Å; S8-T12 PolarHBondContact O-N 3.23Å; S8-T12 PolarHBondContact O-OG1 3.46Å
9	I	92.2	Very high	89.8	Confident	74 Å²	74	70.2 Å²	70.2	38%	0.379	38%	0.376	S	S	.	.	H	α-helix	trans	-59.7	-48.9	177.4	-66.8	165.2	0	0	0	109.8	I5 D6 I11 T12 S13 F60 L66	I5-I9 HydrophobicContact CG2-CD1 4.18Å; I5-I9 WeakPolarHBondContact O-CG1 3.24Å; I5-I9 PolarHBondContact O-N 3.36Å; D6-I9 PolarHBondContact O-N 3.06Å; I9-I11 PolarHBondContact O-N 3.4Å; I9-T12 PolarHBondContact O-N 3.16Å; I9-S13 PolarHBondContact O-N 3.07Å; I9-S13 PolarHBondContact O-OG 3.39Å; I9-F60 HydrophobicContact CG2-CZ 4.47Å; I9-L66 HydrophobicContact CB-CD2 4.47Å; I9-L66 HydrophobicContact CD1-CD2 4.07Å
10	M	93.4	Very high	89.6	Confident	9 Å²	9	72.7 Å²	72.7	4%	0.044	38%	0.384	C	S	.	.	H	α-helix	trans	-62.8	-38.3	178.9	-67.7	-56.8	-52.4	0	0	113	D6 S7 S13 Q14 T53 L57 F60 L66	D6-M10 WeakPolarHBondContact O-CG 3.4Å; D6-M10 PolarHBondContact O-N 3.37Å; S7-M10 PolarHBondContact O-N 3.45Å; M10-S13 PolarHBondContact O-OG 3.48Å; M10-Q14 VanDerWaalsContact O-CB 3.27Å; M10-Q14 WeakPolarHBondContact O-CB 3.48Å; M10-Q14 PolarHBondContact O-N 2.93Å; M10-T53 HydrophobicContact CE-CG2 3.46Å; M10-T53 VanDerWaalsContact CE-CG2 3.46Å; M10-L57 HydrophobicContact CE-CD1 4.44Å; M10-L57 HydrophobicContact CE-CD2 3.58Å; M10-L57 HydrophobicContact CE-CG 3.85Å; M10-L57 HydrophobicContact SD-CD2 3.97Å; M10-F60 HydrophobicContact SD-CD2 3.84Å; M10-F60 HydrophobicContact SD-CE2 3.6Å; M10-L66 HydrophobicContact CG-CD1 4.12Å; M10-L66 HydrophobicContact SD-CD1 3.71Å
11	I	93.2	Very high	89.4	Confident	100 Å²	100	69.2 Å²	69.2	51%	0.513	37%	0.365	S	S	.	.	H	α-helix	trans	-69.1	-41.1	176.9	-72.1	161.3	0	0	0	110.4	S7 S8 I9 Q14 I15	S7-I11 WeakPolarHBondContact O-CB 3.2Å; S7-I11 WeakPolarHBondContact O-CD1 3.26Å; S7-I11 VanDerWaalsContact O-CG1 3.25Å; S7-I11 WeakPolarHBondContact O-CG1 3.38Å; S7-I11 PolarHBondContact O-N 3.46Å; S8-I11 PolarHBondContact O-N 2.89Å; I9-I11 PolarHBondContact O-N 3.4Å; I11-Q14 PolarHBondContact O-N 2.63Å; I11-I15 HydrophobicContact CG2-CD1 3.79Å; I11-I15 HydrophobicContact CG2-CG1 4.4Å; I11-I15 VanDerWaalsContact O-CG1 3.27Å; I11-I15 WeakPolarHBondContact O-CG1 3.49Å; I11-I15 PolarHBondContact O-N 2.61Å
12	T	93.9	Very high	90.7	Very high	77 Å²	77	62.9 Å²	62.9	47%	0.472	33%	0.331	S	S	.	.	H	α-helix	trans	-61.5	-46.4	177.4	-61.3	0	0	0	0	111.1	S8 I9 I15 L16	S8-T12 WeakPolarHBondContact O-CB 3.49Å; S8-T12 PolarHBondContact O-N 3.23Å; S8-T12 PolarHBondContact O-OG1 3.46Å; I9-T12 PolarHBondContact O-N 3.16Å; T12-I15 PolarHBondContact O-N 3.38Å; T12-L16 HydrophobicContact CG2-CD1 4.42Å; T12-L16 WeakPolarHBondContact O-CG 3.19Å; T12-L16 PolarHBondContact O-N 2.76Å; T12-L16 VanDerWaalsContact O-N 3.08Å
13	S	92.9	Very high	90.9	Very high	9 Å²	9	65.2 Å²	65.2	6%	0.063	34%	0.34	C	S	.	.	H	α-helix	trans	-63.8	-41.1	176.6	66	0	0	0	0	112.4	I9 M10 I15 L16 F17 E56	I9-S13 PolarHBondContact O-N 3.07Å; I9-S13 PolarHBondContact O-OG 3.39Å; M10-S13 PolarHBondContact O-OG 3.48Å; S13-I15 PolarHBondContact O-N 3.02Å; S13-L16 WeakPolarHBondContact O-CB 3.25Å; S13-L16 PolarHBondContact O-N 2.95Å; S13-L16 VanDerWaalsContact O-N 3.15Å; S13-F17 WeakPolarHBondContact O-CD2 3.45Å; S13-F17 WeakPolarHBondContact O-CG 3.33Å; S13-F17 PolarHBondContact O-N 2.86Å; S13-E56 VanDerWaalsContact CB-CD 3.46Å; S13-E56 WeakPolarHBondContact CB-OE1 3.47Å; S13-E56 WeakPolarHBondContact CB-OE2 3.37Å; S13-E56 VanDerWaalsContact OG-CD 3.29Å; S13-E56 PolarHBondContact OG-OE1 3.46Å; S13-E56 PolarHBondContact OG-OE2 3.22Å
14	Q	93.8	Very high	90.5	Very high	32 Å²	32	62.1 Å²	62.1	15%	0.15	33%	0.326	C	S	.	.	H	α-helix	trans	-58.4	-44.3	175.6	-172.3	75.5	24.7	0	0	112.3	M10 I11 L16 F17 F18 F50 T53	M10-Q14 VanDerWaalsContact O-CB 3.27Å; M10-Q14 WeakPolarHBondContact O-CB 3.48Å; M10-Q14 PolarHBondContact O-N 2.93Å; I11-Q14 PolarHBondContact O-N 2.63Å; Q14-L16 VanDerWaalsContact C-N 3.34Å; Q14-F17 PolarHBondContact O-N 3.23Å; Q14-F18 WeakPolarHBondContact O-CB 3.34Å; Q14-F18 PolarHBondContact O-N 2.72Å; Q14-F50 VanDerWaalsContact NE2-CD2 3.27Å; Q14-T53 PolarHBondContact OE1-OG1 3.04Å
15	I	94.4	Very high	89.8	Confident	112 Å²	112	56.4 Å²	56.4	57%	0.574	30%	0.296	S	S	*	.	H	α-helix	trans	-64.3	-41.5	177.3	-67.2	165.9	0	0	0	110	I11 T12 S13 F18 G19	I11-I15 HydrophobicContact CG2-CD1 3.79Å; I11-I15 HydrophobicContact CG2-CG1 4.4Å; I11-I15 VanDerWaalsContact O-CG1 3.27Å; I11-I15 WeakPolarHBondContact O-CG1 3.49Å; I11-I15 PolarHBondContact O-N 2.61Å; T12-I15 PolarHBondContact O-N 3.38Å; S13-I15 PolarHBondContact O-N 3.02Å; I15-F18 PolarHBondContact O-N 3.37Å; I15-G19 PolarHBondContact O-N 3.29Å
16	L	93.3	Very high	89	Confident	118 Å²	118	54.7 Å²	54.7	62%	0.618	29%	0.287	S	S	*	.	H	α-helix	trans	-62.4	-46.1	176.3	-69.9	173.3	0	0	0	111.9	T12 S13 Q14 F18 G19 F20	T12-L16 HydrophobicContact CG2-CD1 4.42Å; T12-L16 WeakPolarHBondContact O-CG 3.19Å; T12-L16 PolarHBondContact O-N 2.76Å; T12-L16 VanDerWaalsContact O-N 3.08Å; S13-L16 WeakPolarHBondContact O-CB 3.25Å; S13-L16 PolarHBondContact O-N 2.95Å; S13-L16 VanDerWaalsContact O-N 3.15Å; Q14-L16 VanDerWaalsContact C-N 3.34Å; L16-F18 VanDerWaalsContact C-N 3.34Å; L16-F18 PolarHBondContact O-N 2.92Å; L16-G19 PolarHBondContact O-N 3.41Å; L16-F20 PolarHBondContact O-N 3.3Å
17	F	91.9	Very high	88.2	Confident	56 Å²	56	63 Å²	63	25%	0.246	32%	0.317	C	S	.	.	H	α-helix	trans	-65.4	-37.4	177	-63	-38.4	0	0	0	112.4	S13 Q14 F20 G21 A49 C52 E56	S13-F17 WeakPolarHBondContact O-CD2 3.45Å; S13-F17 WeakPolarHBondContact O-CG 3.33Å; S13-F17 PolarHBondContact O-N 2.86Å; Q14-F17 PolarHBondContact O-N 3.23Å; F17-F20 PolarHBondContact O-N 3.38Å; F17-G21 PolarHBondContact O-N 2.87Å; F17-A49 HydrophobicContact CB-CB 4.02Å; F17-C52 HydrophobicContact CB-CB 4.07Å; F17-C52 HydrophobicContact CD1-CB 3.9Å; F17-C52 HydrophobicContact CD2-CB 3.59Å; F17-C52 HydrophobicContact CE1-CB 4.21Å; F17-C52 HydrophobicContact CE2-CB 3.91Å; F17-C52 HydrophobicContact CG-CB 3.6Å; F17-C52 HydrophobicContact CZ-CB 4.22Å; F17-E56 HydrophobicContact CE2-CB 4.11Å; F17-E56 WeakPolarHBondContact CE2-OE2 3.44Å; F17-E56 HydrophobicContact CZ-CB 4.33Å
18	F	92.9	Very high	87	Confident	63 Å²	63	67.1 Å²	67.1	28%	0.276	34%	0.335	S	S	.	.	H	α-helix	trans	-62.2	-46.9	172.9	179.3	-92.6	0	0	0	111.4	Q14 I15 L16 F20 G21 W22 S45 V46 A49	Q14-F18 WeakPolarHBondContact O-CB 3.34Å; Q14-F18 PolarHBondContact O-N 2.72Å; I15-F18 PolarHBondContact O-N 3.37Å; L16-F18 VanDerWaalsContact C-N 3.34Å; L16-F18 PolarHBondContact O-N 2.92Å; F18-F20 VanDerWaalsContact C-N 3.33Å; F18-F20 PolarHBondContact O-N 2.88Å; F18-G21 PolarHBondContact O-N 3.19Å; F18-W22 AromaticContact CE1-CE3 3.98Å; F18-W22 HydrophobicContact CE1-CE3 3.98Å; F18-W22 AromaticContact CZ-CE3 3.66Å; F18-W22 HydrophobicContact CZ-CE3 3.66Å; F18-W22 HydrophobicContact CZ-CZ3 4.07Å; F18-W22 VanDerWaalsContact O-CB 3.29Å; F18-W22 WeakPolarHBondContact O-CB 3.5Å; F18-W22 PolarHBondContact O-N 2.89Å; F18-S45 VanDerWaalsContact CE2-CB 3.49Å; F18-V46 HydrophobicContact CD2-CG2 4Å; F18-V46 HydrophobicContact CE2-CG2 3.69Å; F18-A49 HydrophobicContact CB-CB 4.01Å
19	G	89.4	Confident	85.6	Confident	31 Å²	31	63.9 Å²	63.9	32%	0.32	31%	0.312	S	S	.	.	H	α-helix	trans	-60.2	-41.7	176.3	0	0	0	0	0	112.5	I15 L16 W22 L23	I15-G19 PolarHBondContact O-N 3.29Å; L16-G19 PolarHBondContact O-N 3.41Å; G19-W22 PolarHBondContact O-N 3.33Å; G19-L23 WeakPolarHBondContact O-CB 3.41Å; G19-L23 VanDerWaalsContact O-CG 3.31Å; G19-L23 WeakPolarHBondContact O-CG 3.41Å; G19-L23 PolarHBondContact O-N 3.44Å
20	F	86.8	Confident	84.2	Confident	120 Å²	120	61 Å²	61	53%	0.526	30%	0.296	S	S	.	.	H	α-helix	trans	-65.1	-46.3	174.8	-176.1	-92.6	0	0	0	112.1	L16 F17 F18 W22 L23 F24 F48	L16-F20 PolarHBondContact O-N 3.3Å; F17-F20 PolarHBondContact O-N 3.38Å; F18-F20 VanDerWaalsContact C-N 3.33Å; F18-F20 PolarHBondContact O-N 2.88Å; F20-W22 VanDerWaalsContact C-N 3.29Å; F20-W22 PolarHBondContact O-N 3.11Å; F20-L23 PolarHBondContact O-N 2.71Å; F20-F24 WeakPolarHBondContact O-CB 3.36Å; F20-F24 PolarHBondContact O-N 3.2Å; F20-F48 AromaticContact CD1-CE1 3.56Å; F20-F48 HydrophobicContact CD1-CE1 3.56Å; F20-F48 AromaticContact CD1-CZ 3.64Å; F20-F48 HydrophobicContact CD1-CZ 3.64Å; F20-F48 HydrophobicContact CE1-CE1 4.25Å; F20-F48 AromaticContact CE1-CZ 3.85Å; F20-F48 HydrophobicContact CE1-CZ 3.85Å
21	G	83.8	Confident	82.6	Confident	0 Å²	0	68 Å²	68	0%	0	33%	0.327	C	S	.	.	H	α-helix	trans	-59.8	-39.9	176	0	0	0	0	0	112.4	F17 F18 F24 F25	F17-G21 PolarHBondContact O-N 2.87Å; F18-G21 PolarHBondContact O-N 3.19Å; G21-F24 PolarHBondContact O-N 3.01Å; G21-F25 WeakPolarHBondContact O-CB 3.37Å; G21-F25 PolarHBondContact O-N 3.26Å
22	W	87.1	Confident	80.7	Confident	59 Å²	59	68.7 Å²	68.7	22%	0.223	33%	0.332	C	S	.	.	H	α-helix	trans	-63.8	-46.9	175.1	-172.2	-82.8	0	0	0	112.3	F18 G19 F20 F25 M26 Y38 Q41 V42 S45	F18-W22 AromaticContact CE1-CE3 3.98Å; F18-W22 HydrophobicContact CE1-CE3 3.98Å; F18-W22 AromaticContact CZ-CE3 3.66Å; F18-W22 HydrophobicContact CZ-CE3 3.66Å; F18-W22 HydrophobicContact CZ-CZ3 4.07Å; F18-W22 VanDerWaalsContact O-CB 3.29Å; F18-W22 WeakPolarHBondContact O-CB 3.5Å; F18-W22 PolarHBondContact O-N 2.89Å; G19-W22 PolarHBondContact O-N 3.33Å; F20-W22 VanDerWaalsContact C-N 3.29Å; F20-W22 PolarHBondContact O-N 3.11Å; W22-F25 WeakPolarHBondContact O-CB 3.5Å; W22-F25 PolarHBondContact O-N 2.91Å; W22-M26 WeakPolarHBondContact O-CG 3.36Å; W22-M26 PolarHBondContact O-N 3.27Å; W22-Y38 AromaticContact CH2-CD2 3.65Å; W22-Y38 HydrophobicContact CH2-CD2 3.65Å; W22-Y38 AromaticContact CH2-CE2 3.26Å; W22-Y38 HydrophobicContact CH2-CE2 3.26Å; W22-Y38 AromaticContact CH2-CZ 3.93Å; W22-Y38 HydrophobicContact CZ2-CD2 4.31Å; W22-Y38 AromaticContact CZ2-CE2 3.91Å; W22-Y38 HydrophobicContact CZ2-CE2 3.91Å; W22-Y38 HydrophobicContact CZ3-CE2 4.19Å; W22-Q41 HydrophobicContact CD2-CG 4.09Å; W22-Q41 VanDerWaalsContact CD2-NE2 3.31Å; W22-Q41 HydrophobicContact CE3-CG 3.73Å; W22-Q41 HydrophobicContact CH2-CB 4.25Å; W22-Q41 HydrophobicContact CH2-CG 3.64Å; W22-Q41 HydrophobicContact CZ2-CG 4.07Å; W22-Q41 HydrophobicContact CZ3-CB 4.19Å; W22-Q41 HydrophobicContact CZ3-CG 3.5Å; W22-Q41 VanDerWaalsContact CZ3-CG 3.5Å; W22-V42 HydrophobicContact CH2-CG2 4.28Å; W22-V42 HydrophobicContact CZ3-CG2 3.72Å; W22-S45 WeakPolarHBondContact CA-OG 3.46Å; W22-S45 PolarHBondContact N-OG 2.91Å
23	L	84.4	Confident	79	Confident	90 Å²	90	67.1 Å²	67.1	47%	0.471	32%	0.317	S	S	.	.	H	α-helix	trans	-64	-42.9	177.1	-76.6	171.4	0	0	0	111.7	G19 F20 F25 M26 R27	G19-L23 WeakPolarHBondContact O-CB 3.41Å; G19-L23 VanDerWaalsContact O-CG 3.31Å; G19-L23 WeakPolarHBondContact O-CG 3.41Å; G19-L23 PolarHBondContact O-N 3.44Å; F20-L23 PolarHBondContact O-N 2.71Å; L23-F25 VanDerWaalsContact C-N 3.34Å; L23-M26 PolarHBondContact O-N 2.99Å; L23-R27 WeakPolarHBondContact O-CB 3.44Å; L23-R27 PolarHBondContact O-N 2.89Å
24	F	80.4	Confident	76.9	Confident	27 Å²	27	75.7 Å²	75.7	12%	0.118	36%	0.356	C	S	.	.	H	α-helix	trans	-59.6	-46.3	176	178.3	-100.1	0	0	0	111	F20 G21 M26 Q28 F44 L337	F20-F24 WeakPolarHBondContact O-CB 3.36Å; F20-F24 PolarHBondContact O-N 3.2Å; G21-F24 PolarHBondContact O-N 3.01Å; F24-M26 PolarHBondContact O-N 3.44Å; F24-Q28 HydrophobicContact CD2-CB 3.99Å; F24-Q28 HydrophobicContact CD2-CG 4.37Å; F24-Q28 HydrophobicContact CE2-CB 3.86Å; F24-Q28 HydrophobicContact CE2-CG 3.79Å; F24-Q28 HydrophobicContact CZ-CB 4.28Å; F24-Q28 HydrophobicContact CZ-CG 4.19Å; F24-Q28 WeakPolarHBondContact O-CA 3.48Å; F24-Q28 WeakPolarHBondContact O-CB 3.29Å; F24-Q28 PolarHBondContact O-N 3.41Å; F24-F44 HydrophobicContact CD1-CE1 4.15Å; F24-F44 HydrophobicContact CD1-CZ 4.18Å; F24-F44 HydrophobicContact CE1-CZ 4.27Å; F24-L337 HydrophobicContact CE1-CD2 4Å; F24-L337 HydrophobicContact CZ-CB 4.29Å; F24-L337 HydrophobicContact CZ-CD1 4.4Å; F24-L337 HydrophobicContact CZ-CD2 4.15Å
25	F	75.4	Confident	74.9	Confident	5 Å²	5	79.3 Å²	79.3	2%	0.022	38%	0.376	C	S	.	.	I	π-helix	trans	-57.3	-49.6	175.3	-173.2	-83.9	0	0	0	112.2	G21 W22 L23 L29 F30 Q41 F44 V357	G21-F25 WeakPolarHBondContact O-CB 3.37Å; G21-F25 PolarHBondContact O-N 3.26Å; W22-F25 WeakPolarHBondContact O-CB 3.5Å; W22-F25 PolarHBondContact O-N 2.91Å; L23-F25 VanDerWaalsContact C-N 3.34Å; F25-L29 HydrophobicContact CD2-CD2 3.91Å; F25-L29 HydrophobicContact CE2-CD2 4.13Å; F25-L29 WeakPolarHBondContact O-CB 3.49Å; F25-L29 PolarHBondContact O-N 3.4Å; F25-F30 AromaticContact CD1-CD2 3.86Å; F25-F30 HydrophobicContact CD1-CD2 3.86Å; F25-F30 HydrophobicContact CD1-CE2 4.48Å; F25-F30 HydrophobicContact CD2-CD2 4.42Å; F25-F30 HydrophobicContact CE1-CB 4.4Å; F25-F30 AromaticContact CE1-CD2 3.26Å; F25-F30 HydrophobicContact CE1-CD2 3.26Å; F25-F30 AromaticContact CE1-CE2 3.58Å; F25-F30 HydrophobicContact CE1-CE2 3.58Å; F25-F30 AromaticContact CE1-CG 3.92Å; F25-F30 HydrophobicContact CE1-CG 3.92Å; F25-F30 HydrophobicContact CE1-CZ 4.47Å; F25-F30 AromaticContact CE2-CD2 3.97Å; F25-F30 HydrophobicContact CE2-CD2 3.97Å; F25-F30 AromaticContact CE2-CE2 3.72Å; F25-F30 HydrophobicContact CE2-CE2 3.72Å; F25-F30 HydrophobicContact CG-CD2 4.41Å; F25-F30 AromaticContact CZ-CD2 3.35Å; F25-F30 HydrophobicContact CZ-CD2 3.35Å; F25-F30 AromaticContact CZ-CE2 3.13Å; F25-F30 HydrophobicContact CZ-CE2 3.13Å; F25-F30 HydrophobicContact CZ-CG 4.34Å; F25-F30 HydrophobicContact CZ-CZ 4.02Å; F25-F30 PolarHBondContact O-N 3.47Å; F25-F30 VanDerWaalsContact O-N 3.14Å; F25-Q41 HydrophobicContact CD1-CB 4.09Å; F25-Q41 HydrophobicContact CD1-CG 3.51Å; F25-Q41 HydrophobicContact CD2-CG 4.49Å; F25-Q41 HydrophobicContact CE1-CB 3.64Å; F25-Q41 HydrophobicContact CE1-CG 3.61Å; F25-Q41 HydrophobicContact CE2-CB 4.33Å; F25-Q41 HydrophobicContact CG-CG 3.97Å; F25-Q41 HydrophobicContact CZ-CB 3.76Å; F25-Q41 HydrophobicContact CZ-CG 4.11Å; F25-F44 HydrophobicContact CB-CD1 4.15Å; F25-F44 HydrophobicContact CB-CE1 4.33Å; F25-F44 HydrophobicContact CD2-CB 3.96Å; F25-F44 AromaticContact CD2-CD1 3.53Å; F25-F44 HydrophobicContact CD2-CD1 3.53Å; F25-F44 HydrophobicContact CD2-CD2 4.49Å; F25-F44 HydrophobicContact CD2-CE1 4.16Å; F25-F44 AromaticContact CD2-CG 3.72Å; F25-F44 HydrophobicContact CD2-CG 3.72Å; F25-F44 HydrophobicContact CE2-CB 3.96Å; F25-F44 HydrophobicContact CE2-CD1 4.37Å; F25-F44 HydrophobicContact CE2-CG 4.12Å; F25-F44 HydrophobicContact CG-CD1 4.32Å; F25-V357 HydrophobicContact CD2-CG1 4.34Å; F25-V357 HydrophobicContact CE2-CG1 3.35Å; F25-V357 HydrophobicContact CZ-CG1 3.98Å
26	M	74.4	Confident	73.3	Confident	67 Å²	67	82.1 Å²	82.1	33%	0.33	38%	0.379	S	S	.	.	I	π-helix	trans	-67	-42	-177.1	-73.1	-65.7	-76.7	0	0	113.1	W22 L23 F24 Q41	W22-M26 WeakPolarHBondContact O-CG 3.36Å; W22-M26 PolarHBondContact O-N 3.27Å; L23-M26 PolarHBondContact O-N 2.99Å; F24-M26 PolarHBondContact O-N 3.44Å; M26-Q41 PolarHBondContact SD-NE2 3.24Å
27	R	73.6	Confident	72.3	Confident	187 Å²	187	80.1 Å²	80.1	71%	0.706	37%	0.366	S	S	*	.	I	π-helix	trans	-89.4	-32.9	-171.9	-69.5	-172.3	173.4	-178.9	-0.6	113.7	L23	L23-R27 WeakPolarHBondContact O-CB 3.44Å; L23-R27 PolarHBondContact O-N 2.89Å
28	Q	67	Low	71.8	Confident	105 Å²	105	84.8 Å²	84.8	49%	0.491	38%	0.383	S	S	.	.	I	π-helix	trans	-107.5	-36.6	-169.9	-156	106.3	13.3	0	0	112.8	F24 T341	F24-Q28 HydrophobicContact CD2-CB 3.99Å; F24-Q28 HydrophobicContact CD2-CG 4.37Å; F24-Q28 HydrophobicContact CE2-CB 3.86Å; F24-Q28 HydrophobicContact CE2-CG 3.79Å; F24-Q28 HydrophobicContact CZ-CB 4.28Å; F24-Q28 HydrophobicContact CZ-CG 4.19Å; F24-Q28 WeakPolarHBondContact O-CA 3.48Å; F24-Q28 WeakPolarHBondContact O-CB 3.29Å; F24-Q28 PolarHBondContact O-N 3.41Å; Q28-T341 HydrophobicContact CG-CG2 4.47Å
29	L	64	Low	71.4	Confident	1 Å²	1	84.9 Å²	84.9	1%	0.005	39%	0.389	C	S	.	.	I	π-helix	trans	-97.1	-32.8	-170.2	-152.2	76.8	0	0	0	113.1	F25 F344 V357 L360	F25-L29 HydrophobicContact CD2-CD2 3.91Å; F25-L29 HydrophobicContact CE2-CD2 4.13Å; F25-L29 WeakPolarHBondContact O-CB 3.49Å; F25-L29 PolarHBondContact O-N 3.4Å; L29-F344 HydrophobicContact CD1-CD1 4.48Å; L29-F344 HydrophobicContact CD1-CG 4.48Å; L29-F344 WeakPolarHBondContact O-CE1 3.23Å; L29-V357 HydrophobicContact CD2-CG1 4.1Å; L29-V357 HydrophobicContact CD2-CG2 3.9Å; L29-L360 HydrophobicContact CD1-CD2 3.69Å; L29-L360 HydrophobicContact CD2-CD2 3.64Å; L29-L360 HydrophobicContact CG-CD2 4.32Å
30	F	62.8	Low	71.1	Confident	13 Å²	13	83.4 Å²	83.4	6%	0.057	37%	0.374	C	S	.	.	S	Bend	trans	-120.6	17.8	-173	-92.2	-92.1	0	0	0	115.1	F25 D32 Y33 V357	F25-F30 AromaticContact CD1-CD2 3.86Å; F25-F30 HydrophobicContact CD1-CD2 3.86Å; F25-F30 HydrophobicContact CD1-CE2 4.48Å; F25-F30 HydrophobicContact CD2-CD2 4.42Å; F25-F30 HydrophobicContact CE1-CB 4.4Å; F25-F30 AromaticContact CE1-CD2 3.26Å; F25-F30 HydrophobicContact CE1-CD2 3.26Å; F25-F30 AromaticContact CE1-CE2 3.58Å; F25-F30 HydrophobicContact CE1-CE2 3.58Å; F25-F30 AromaticContact CE1-CG 3.92Å; F25-F30 HydrophobicContact CE1-CG 3.92Å; F25-F30 HydrophobicContact CE1-CZ 4.47Å; F25-F30 AromaticContact CE2-CD2 3.97Å; F25-F30 HydrophobicContact CE2-CD2 3.97Å; F25-F30 AromaticContact CE2-CE2 3.72Å; F25-F30 HydrophobicContact CE2-CE2 3.72Å; F25-F30 HydrophobicContact CG-CD2 4.41Å; F25-F30 AromaticContact CZ-CD2 3.35Å; F25-F30 HydrophobicContact CZ-CD2 3.35Å; F25-F30 AromaticContact CZ-CE2 3.13Å; F25-F30 HydrophobicContact CZ-CE2 3.13Å; F25-F30 HydrophobicContact CZ-CG 4.34Å; F25-F30 HydrophobicContact CZ-CZ 4.02Å; F25-F30 PolarHBondContact O-N 3.47Å; F25-F30 VanDerWaalsContact O-N 3.14Å; F30-D32 PolarHBondContact O-N 2.88Å; F30-Y33 HydrophobicContact CD1-CG 4.28Å; F30-Y33 HydrophobicContact CE1-CG 4.42Å; F30-Y33 PolarHBondContact O-N 3.46Å; F30-V357 HydrophobicContact CD2-CG2 4.47Å; F30-V357 HydrophobicContact CE2-CB 4.25Å; F30-V357 HydrophobicContact CE2-CG1 4.1Å; F30-V357 HydrophobicContact CE2-CG2 3.35Å; F30-V357 HydrophobicContact CZ-CG2 3.67Å
31	K	59.2	Low	71	Confident	156 Å²	156	78 Å²	78	68%	0.678	35%	0.35	S	S	*	.	T	Hydrogen-bonded Turn	trans	-50.9	-31.2	-175.1	-166.5	-179.4	175.4	-171.1	0	113.5
32	D	54.1	Low	71.3	Confident	115 Å²	115	80 Å²	80	62%	0.615	36%	0.362	S	S	*	.	T	Hydrogen-bonded Turn	trans	-119.4	12.7	-172.1	-49.4	-53.4	0	0	0	114.4	F30	F30-D32 PolarHBondContact O-N 2.88Å
33	Y	58.2	Low	71.4	Confident	43 Å²	43	77.9 Å²	77.9	17%	0.169	36%	0.355	C	S	.	.			trans	-113.7	120.4	-174.3	-82.6	-70.4	0	0	0	113.3	F30 F344 S348	F30-Y33 HydrophobicContact CD1-CG 4.28Å; F30-Y33 HydrophobicContact CE1-CG 4.42Å; F30-Y33 PolarHBondContact O-N 3.46Å; Y33-F344 HydrophobicContact CD2-CE1 4.16Å; Y33-F344 AromaticContact CD2-CZ 3.99Å; Y33-F344 HydrophobicContact CD2-CZ 3.99Å; Y33-F344 AromaticContact CE2-CE1 3.74Å; Y33-F344 HydrophobicContact CE2-CE1 3.74Å; Y33-F344 AromaticContact CE2-CZ 3.7Å; Y33-F344 HydrophobicContact CE2-CZ 3.7Å; Y33-S348 WeakPolarHBondContact OH-CB 3.25Å; Y33-S348 PolarHBondContact OH-O 3.23Å; Y33-S348 VanDerWaalsContact OH-O 3.05Å; Y33-S348 PolarHBondContact OH-OG 3.05Å
34	E	48.7	Very low	71.6	Confident	189 Å²	189	73.6 Å²	73.6	88%	0.883	33%	0.333	S	S	*	.	S	Bend	trans	-76.9	-23	-168.8	-66.2	-178.4	152.3	0	0	115.6
35	I	51.5	Low	72.1	Confident	109 Å²	109	72.3 Å²	72.3	56%	0.559	33%	0.327	S	S	*	.			trans	-102.3	92.6	-175.3	-53.8	171.1	0	0	0	110.1	Q37	I35-Q37 PolarHBondContact O-N 3.34Å
36	R	60.5	Low	72.9	Confident	171 Å²	171	73.9 Å²	73.9	65%	0.645	34%	0.337	S	S	*	.			trans	-88.4	100.9	176.8	-69.7	-178.5	-69.9	-132.8	-2.3	110.9	Y38	R36-Y38 PolarHBondContact O-N 2.96Å
37	Q	71.8	Confident	73.7	Confident	75 Å²	75	70.7 Å²	70.7	35%	0.35	32%	0.321	S	S	.	.			trans	-85.1	111.1	165	-81.7	178.5	-30.6	0	0	110.5	I35 V39 V40 Q41 N354	I35-Q37 PolarHBondContact O-N 3.34Å; Q37-V39 PolarHBondContact O-N 3.49Å; Q37-V39 VanDerWaalsContact O-N 3.16Å; Q37-V40 HydrophobicContact CB-CG2 4.22Å; Q37-V40 PolarHBondContact O-N 3.22Å; Q37-V40 VanDerWaalsContact O-N 3.14Å; Q37-Q41 PolarHBondContact O-N 2.65Å; Q37-N354 PolarHBondContact OE1-ND2 3.17Å
38	Y	81.6	Confident	74.4	Confident	154 Å²	154	62.1 Å²	62.1	60%	0.604	29%	0.289	S	S	*	.	H	α-helix	trans	-52.3	-38.1	-179.2	-175.4	-96.1	0	0	0	112.8	W22 R36 V40 Q41 V42	W22-Y38 AromaticContact CH2-CD2 3.65Å; W22-Y38 HydrophobicContact CH2-CD2 3.65Å; W22-Y38 AromaticContact CH2-CE2 3.26Å; W22-Y38 HydrophobicContact CH2-CE2 3.26Å; W22-Y38 AromaticContact CH2-CZ 3.93Å; W22-Y38 HydrophobicContact CZ2-CD2 4.31Å; W22-Y38 AromaticContact CZ2-CE2 3.91Å; W22-Y38 HydrophobicContact CZ2-CE2 3.91Å; W22-Y38 HydrophobicContact CZ3-CE2 4.19Å; R36-Y38 PolarHBondContact O-N 2.96Å; Y38-V40 PolarHBondContact O-N 3.13Å; Y38-Q41 WeakPolarHBondContact O-CB 3.32Å; Y38-Q41 PolarHBondContact O-N 3.47Å; Y38-V42 HydrophobicContact CD1-CG2 3.76Å; Y38-V42 HydrophobicContact CE1-CG2 3.34Å; Y38-V42 HydrophobicContact CE2-CG2 4.39Å; Y38-V42 HydrophobicContact CG-CG2 4.42Å; Y38-V42 WeakPolarHBondContact O-CG2 3.27Å; Y38-V42 PolarHBondContact O-N 2.95Å
39	V	84.8	Confident	75.5	Confident	66 Å²	66	57.1 Å²	57.1	40%	0.4	27%	0.266	S	S	.	.	H	α-helix	trans	-61.1	-44.5	-179.2	179.9	0	0	0	0	112.2	Q37 Q41 V42 I43 Y93	Q37-V39 PolarHBondContact O-N 3.49Å; Q37-V39 VanDerWaalsContact O-N 3.16Å; V39-Q41 VanDerWaalsContact C-N 3.3Å; V39-Q41 PolarHBondContact O-N 2.88Å; V39-V42 PolarHBondContact O-N 3.36Å; V39-I43 HydrophobicContact CG1-CD1 3.73Å; V39-I43 HydrophobicContact CG1-CG1 4.45Å; V39-I43 WeakPolarHBondContact O-CD1 3.44Å; V39-I43 VanDerWaalsContact O-CG1 3.23Å; V39-I43 WeakPolarHBondContact O-CG1 3.35Å; V39-I43 PolarHBondContact O-N 3.34Å; V39-Y93 HydrophobicContact CG1-CD1 4.18Å; V39-Y93 HydrophobicContact CG1-CE1 3.56Å; V39-Y93 HydrophobicContact CG1-CE2 4.41Å
40	V	83	Confident	76.9	Confident	0 Å²	0	59 Å²	59	0%	0	27%	0.274	C	S	.	.	H	α-helix	trans	-64.7	-39.8	179.7	176.2	0	0	0	0	110.7	Q37 Y38 I43 F44 F97 N354 V357 L358	Q37-V40 HydrophobicContact CB-CG2 4.22Å; Q37-V40 PolarHBondContact O-N 3.22Å; Q37-V40 VanDerWaalsContact O-N 3.14Å; Y38-V40 PolarHBondContact O-N 3.13Å; V40-I43 PolarHBondContact O-N 3.09Å; V40-F44 WeakPolarHBondContact O-CB 3.45Å; V40-F44 PolarHBondContact O-N 2.94Å; V40-F97 HydrophobicContact CG2-CE2 3.67Å; V40-F97 HydrophobicContact CG2-CZ 3.98Å; V40-N354 HydrophobicContact CG2-CB 4.2Å; V40-V357 HydrophobicContact CG1-CB 4.01Å; V40-V357 HydrophobicContact CG1-CG1 3.49Å; V40-V357 VanDerWaalsContact CG1-CG1 3.49Å; V40-L358 HydrophobicContact CG1-CD2 4.08Å; V40-L358 HydrophobicContact CG1-CG 3.99Å; V40-L358 HydrophobicContact CG2-CD1 4.27Å; V40-L358 HydrophobicContact CG2-CD2 4.43Å; V40-L358 HydrophobicContact CG2-CG 4.33Å
41	Q	85.4	Confident	78.1	Confident	7 Å²	7	58.4 Å²	58.4	3%	0.033	27%	0.271	C	S	.	.	H	α-helix	trans	-65.9	-43.8	177.8	-176.9	174.1	7	0	0	112.5	W22 F25 M26 Q37 Y38 V39 F44 S45	W22-Q41 HydrophobicContact CD2-CG 4.09Å; W22-Q41 VanDerWaalsContact CD2-NE2 3.31Å; W22-Q41 HydrophobicContact CE3-CG 3.73Å; W22-Q41 HydrophobicContact CH2-CB 4.25Å; W22-Q41 HydrophobicContact CH2-CG 3.64Å; W22-Q41 HydrophobicContact CZ2-CG 4.07Å; W22-Q41 HydrophobicContact CZ3-CB 4.19Å; W22-Q41 HydrophobicContact CZ3-CG 3.5Å; W22-Q41 VanDerWaalsContact CZ3-CG 3.5Å; F25-Q41 HydrophobicContact CD1-CB 4.09Å; F25-Q41 HydrophobicContact CD1-CG 3.51Å; F25-Q41 HydrophobicContact CD2-CG 4.49Å; F25-Q41 HydrophobicContact CE1-CB 3.64Å; F25-Q41 HydrophobicContact CE1-CG 3.61Å; F25-Q41 HydrophobicContact CE2-CB 4.33Å; F25-Q41 HydrophobicContact CG-CG 3.97Å; F25-Q41 HydrophobicContact CZ-CB 3.76Å; F25-Q41 HydrophobicContact CZ-CG 4.11Å; M26-Q41 PolarHBondContact SD-NE2 3.24Å; Q37-Q41 PolarHBondContact O-N 2.65Å; Y38-Q41 WeakPolarHBondContact O-CB 3.32Å; Y38-Q41 PolarHBondContact O-N 3.47Å; V39-Q41 VanDerWaalsContact C-N 3.3Å; V39-Q41 PolarHBondContact O-N 2.88Å; Q41-F44 PolarHBondContact O-N 3.33Å; Q41-S45 WeakPolarHBondContact O-CB 3.21Å; Q41-S45 PolarHBondContact O-N 3.22Å; Q41-S45 PolarHBondContact O-OG 3.05Å
42	V	89.9	Confident	79.3	Confident	40 Å²	40	51.9 Å²	51.9	24%	0.242	25%	0.245	C	C	.	.	H	α-helix	trans	-61.2	-49.8	174.4	172.4	0	0	0	0	109.6	W22 Y38 V39 F44 S45 V46	W22-V42 HydrophobicContact CH2-CG2 4.28Å; W22-V42 HydrophobicContact CZ3-CG2 3.72Å; Y38-V42 HydrophobicContact CD1-CG2 3.76Å; Y38-V42 HydrophobicContact CE1-CG2 3.34Å; Y38-V42 HydrophobicContact CE2-CG2 4.39Å; Y38-V42 HydrophobicContact CG-CG2 4.42Å; Y38-V42 WeakPolarHBondContact O-CG2 3.27Å; Y38-V42 PolarHBondContact O-N 2.95Å; V39-V42 PolarHBondContact O-N 3.36Å; V42-F44 VanDerWaalsContact C-N 3.33Å; V42-F44 PolarHBondContact O-N 3.44Å; V42-S45 PolarHBondContact O-N 2.53Å; V42-V46 HydrophobicContact CG1-CG2 3.9Å; V42-V46 WeakPolarHBondContact O-CB 3.43Å; V42-V46 VanDerWaalsContact O-CG2 3.24Å; V42-V46 WeakPolarHBondContact O-CG2 3.29Å; V42-V46 PolarHBondContact O-N 2.83Å
43	I	89.8	Confident	81	Confident	16 Å²	16	46.5 Å²	46.5	8%	0.082	22%	0.217	C	C	.	.	H	α-helix	trans	-57.8	-46.4	-179.5	-69.7	164.4	0	0	0	111.1	V39 V40 T47 V90 Y93 L358	V39-I43 HydrophobicContact CG1-CD1 3.73Å; V39-I43 HydrophobicContact CG1-CG1 4.45Å; V39-I43 WeakPolarHBondContact O-CD1 3.44Å; V39-I43 VanDerWaalsContact O-CG1 3.23Å; V39-I43 WeakPolarHBondContact O-CG1 3.35Å; V39-I43 PolarHBondContact O-N 3.34Å; V40-I43 PolarHBondContact O-N 3.09Å; I43-T47 WeakPolarHBondContact O-CB 3.36Å; I43-T47 PolarHBondContact O-N 3.41Å; I43-T47 PolarHBondContact O-OG1 3.29Å; I43-V90 HydrophobicContact CG2-CG2 3.57Å; I43-Y93 HydrophobicContact CD1-CD1 4.23Å; I43-Y93 HydrophobicContact CD1-CD2 3.22Å; I43-Y93 HydrophobicContact CD1-CE1 4.42Å; I43-Y93 HydrophobicContact CD1-CE2 3.47Å; I43-Y93 VanDerWaalsContact CD1-CE2 3.47Å; I43-Y93 HydrophobicContact CD1-CG 3.65Å; I43-Y93 HydrophobicContact CG1-CD2 4.46Å; I43-Y93 HydrophobicContact CG1-CE2 4.5Å; I43-L358 HydrophobicContact CB-CD2 4.27Å; I43-L358 HydrophobicContact CD1-CD2 4.15Å; I43-L358 HydrophobicContact CG2-CD2 3.89Å
44	F	87.9	Confident	82.3	Confident	0 Å²	0	44.6 Å²	44.6	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-60.4	-49.4	176.4	178.2	-87.5	0	0	0	111.7	F24 F25 V40 Q41 V42 V46 T47 F48 L360 A361 M364	F24-F44 HydrophobicContact CD1-CE1 4.15Å; F24-F44 HydrophobicContact CD1-CZ 4.18Å; F24-F44 HydrophobicContact CE1-CZ 4.27Å; F25-F44 HydrophobicContact CB-CD1 4.15Å; F25-F44 HydrophobicContact CB-CE1 4.33Å; F25-F44 HydrophobicContact CD2-CB 3.96Å; F25-F44 AromaticContact CD2-CD1 3.53Å; F25-F44 HydrophobicContact CD2-CD1 3.53Å; F25-F44 HydrophobicContact CD2-CD2 4.49Å; F25-F44 HydrophobicContact CD2-CE1 4.16Å; F25-F44 AromaticContact CD2-CG 3.72Å; F25-F44 HydrophobicContact CD2-CG 3.72Å; F25-F44 HydrophobicContact CE2-CB 3.96Å; F25-F44 HydrophobicContact CE2-CD1 4.37Å; F25-F44 HydrophobicContact CE2-CG 4.12Å; F25-F44 HydrophobicContact CG-CD1 4.32Å; V40-F44 WeakPolarHBondContact O-CB 3.45Å; V40-F44 PolarHBondContact O-N 2.94Å; Q41-F44 PolarHBondContact O-N 3.33Å; V42-F44 VanDerWaalsContact C-N 3.33Å; V42-F44 PolarHBondContact O-N 3.44Å; F44-V46 PolarHBondContact O-N 2.97Å; F44-T47 PolarHBondContact O-N 3.47Å; F44-F48 WeakPolarHBondContact O-CB 3.5Å; F44-F48 PolarHBondContact O-N 2.96Å; F44-L360 HydrophobicContact CD2-CD2 4.38Å; F44-L360 HydrophobicContact CE2-CD2 3.66Å; F44-L360 HydrophobicContact CE2-CG 4Å; F44-L360 HydrophobicContact CZ-CD2 4.39Å; F44-A361 HydrophobicContact CB-CB 4.48Å; F44-A361 HydrophobicContact CD2-CB 3.98Å; F44-M364 HydrophobicContact CE2-CE 4.28Å; F44-M364 HydrophobicContact CE2-SD 4.3Å; F44-M364 HydrophobicContact CZ-CE 4.5Å; F44-M364 HydrophobicContact CZ-SD 4.28Å
45	S	90	Very high	83.8	Confident	0 Å²	0	36.1 Å²	36.1	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-68.3	-37	-175.6	-53.1	0	0	0	0	112.2	F18 W22 Q41 V42 A49	F18-S45 VanDerWaalsContact CE2-CB 3.49Å; W22-S45 WeakPolarHBondContact CA-OG 3.46Å; W22-S45 PolarHBondContact N-OG 2.91Å; Q41-S45 WeakPolarHBondContact O-CB 3.21Å; Q41-S45 PolarHBondContact O-N 3.22Å; Q41-S45 PolarHBondContact O-OG 3.05Å; V42-S45 PolarHBondContact O-N 2.53Å; S45-A49 VanDerWaalsContact O-CB 3.32Å; S45-A49 WeakPolarHBondContact O-CB 3.47Å; S45-A49 PolarHBondContact O-N 3.49Å
46	V	92.5	Very high	85.5	Confident	37 Å²	37	32.3 Å²	32.3	22%	0.224	15%	0.149	C	C	.	.	H	α-helix	trans	-65.1	-48	172.1	174.1	0	0	0	0	109.9	F18 V42 F44 F48 A49 F50 I85	F18-V46 HydrophobicContact CD2-CG2 4Å; F18-V46 HydrophobicContact CE2-CG2 3.69Å; V42-V46 HydrophobicContact CG1-CG2 3.9Å; V42-V46 WeakPolarHBondContact O-CB 3.43Å; V42-V46 VanDerWaalsContact O-CG2 3.24Å; V42-V46 WeakPolarHBondContact O-CG2 3.29Å; V42-V46 PolarHBondContact O-N 2.83Å; F44-V46 PolarHBondContact O-N 2.97Å; V46-F48 VanDerWaalsContact C-N 3.29Å; V46-F48 PolarHBondContact O-N 3.29Å; V46-A49 PolarHBondContact O-N 2.87Å; V46-A49 VanDerWaalsContact O-N 3.16Å; V46-F50 HydrophobicContact CG1-CD2 3.55Å; V46-F50 HydrophobicContact CG1-CE2 3.67Å; V46-F50 WeakPolarHBondContact O-CD2 3.45Å; V46-F50 PolarHBondContact O-N 3.03Å; V46-I85 HydrophobicContact CG1-CD1 3.57Å
47	T	90.8	Very high	86.7	Confident	0 Å²	0	24.1 Å²	24.1	0%	0	12%	0.118	C	C	.	.	H	α-helix	trans	-57.8	-45	177.6	-53.5	0	0	0	0	110.8	I43 F44 S51 I85 L86 M364	I43-T47 WeakPolarHBondContact O-CB 3.36Å; I43-T47 PolarHBondContact O-N 3.41Å; I43-T47 PolarHBondContact O-OG1 3.29Å; F44-T47 PolarHBondContact O-N 3.47Å; T47-S51 VanDerWaalsContact O-CB 3.23Å; T47-S51 WeakPolarHBondContact O-CB 3.44Å; T47-S51 PolarHBondContact O-N 3.45Å; T47-S51 PolarHBondContact O-OG 2.99Å; T47-I85 HydrophobicContact CG2-CG2 4.49Å; T47-I85 VanDerWaalsContact OG1-CG2 3.27Å; T47-I85 WeakPolarHBondContact OG1-CG2 3.33Å; T47-L86 HydrophobicContact CG2-CD2 4.22Å; T47-M364 HydrophobicContact CG2-CE 4.08Å
48	F	88.2	Confident	87.1	Confident	7 Å²	7	20.7 Å²	20.7	3%	0.031	10%	0.102	C	C	.	.	H	α-helix	trans	-60	-48	175.4	-178.5	-92.5	0	0	0	111.9	F20 F44 V46 S51 C52 L337 M364	F20-F48 AromaticContact CD1-CE1 3.56Å; F20-F48 HydrophobicContact CD1-CE1 3.56Å; F20-F48 AromaticContact CD1-CZ 3.64Å; F20-F48 HydrophobicContact CD1-CZ 3.64Å; F20-F48 HydrophobicContact CE1-CE1 4.25Å; F20-F48 AromaticContact CE1-CZ 3.85Å; F20-F48 HydrophobicContact CE1-CZ 3.85Å; F44-F48 WeakPolarHBondContact O-CB 3.5Å; F44-F48 PolarHBondContact O-N 2.96Å; V46-F48 VanDerWaalsContact C-N 3.29Å; V46-F48 PolarHBondContact O-N 3.29Å; F48-S51 WeakPolarHBondContact O-CB 3.43Å; F48-S51 PolarHBondContact O-N 2.68Å; F48-C52 VanDerWaalsContact CE1-SG 3.5Å; F48-C52 WeakPolarHBondContact CZ-SG 3.26Å; F48-C52 PolarHBondContact O-N 3.37Å; F48-L337 HydrophobicContact CE2-CD1 4.36Å; F48-M364 HydrophobicContact CB-CE 3.8Å; F48-M364 HydrophobicContact CD2-CE 4.17Å; F48-M364 HydrophobicContact CD2-SD 3.82Å
49	A	91.6	Very high	87	Confident	0 Å²	0	16.6 Å²	16.6	0%	0	9%	0.09	C	C	.	.	H	α-helix	trans	-60.8	-52.6	-178.6	0	0	0	0	0	112.2	F17 F18 S45 V46 S51 C52 T53	F17-A49 HydrophobicContact CB-CB 4.02Å; F18-A49 HydrophobicContact CB-CB 4.01Å; S45-A49 VanDerWaalsContact O-CB 3.32Å; S45-A49 WeakPolarHBondContact O-CB 3.47Å; S45-A49 PolarHBondContact O-N 3.49Å; V46-A49 PolarHBondContact O-N 2.87Å; V46-A49 VanDerWaalsContact O-N 3.16Å; A49-S51 PolarHBondContact O-N 3.02Å; A49-C52 PolarHBondContact O-N 3.42Å; A49-C52 VanDerWaalsContact O-N 3.11Å; A49-T53 PolarHBondContact O-N 3.35Å; A49-T53 PolarHBondContact O-OG1 3.37Å
50	F	91.8	Very high	87	Confident	42 Å²	42	14.7 Å²	14.7	18%	0.184	8%	0.077	C	C	.	.	H	α-helix	trans	-61.5	-29.6	176.9	-82.2	-83.4	0	0	0	112.8	Q14 V46 M54 N78 V81 I82 I85	Q14-F50 VanDerWaalsContact NE2-CD2 3.27Å; V46-F50 HydrophobicContact CG1-CD2 3.55Å; V46-F50 HydrophobicContact CG1-CE2 3.67Å; V46-F50 WeakPolarHBondContact O-CD2 3.45Å; V46-F50 PolarHBondContact O-N 3.03Å; F50-M54 PolarHBondContact O-N 3.19Å; F50-M54 VanDerWaalsContact O-N 3.17Å; F50-N78 WeakPolarHBondContact CD1-OD1 3.42Å; F50-N78 PolarHBondContact O-ND2 3.14Å; F50-V81 HydrophobicContact CD1-CB 3.99Å; F50-V81 HydrophobicContact CD1-CG1 3.82Å; F50-V81 HydrophobicContact CD2-CG1 4.05Å; F50-V81 HydrophobicContact CE1-CB 3.69Å; F50-V81 HydrophobicContact CE1-CG1 3.49Å; F50-V81 VanDerWaalsContact CE1-CG1 3.49Å; F50-V81 HydrophobicContact CE1-CG2 4.19Å; F50-V81 HydrophobicContact CE2-CG1 3.7Å; F50-V81 HydrophobicContact CG-CG1 4.14Å; F50-V81 HydrophobicContact CZ-CB 4.13Å; F50-V81 HydrophobicContact CZ-CG1 3.44Å; F50-V81 VanDerWaalsContact CZ-CG1 3.44Å; F50-V81 HydrophobicContact CZ-CG2 4.48Å; F50-I82 HydrophobicContact CB-CB 4.27Å; F50-I82 HydrophobicContact CB-CD1 4.33Å; F50-I82 HydrophobicContact CB-CG1 4.39Å; F50-I85 HydrophobicContact CD2-CD1 4.07Å
51	S	88.1	Confident	86.9	Confident	0 Å²	0	15.3 Å²	15.3	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-70	-42.6	174.5	-61.1	0	0	0	0	111.9	T47 F48 A49 M54 I82 F368	T47-S51 VanDerWaalsContact O-CB 3.23Å; T47-S51 WeakPolarHBondContact O-CB 3.44Å; T47-S51 PolarHBondContact O-N 3.45Å; T47-S51 PolarHBondContact O-OG 2.99Å; F48-S51 WeakPolarHBondContact O-CB 3.43Å; F48-S51 PolarHBondContact O-N 2.68Å; A49-S51 PolarHBondContact O-N 3.02Å; S51-M54 PolarHBondContact O-N 2.99Å; S51-I82 WeakPolarHBondContact OG-CD1 3.46Å; S51-F368 WeakPolarHBondContact O-CD1 3.32Å
52	C	86.1	Confident	86.4	Confident	18 Å²	18	16 Å²	16	12%	0.122	8%	0.083	C	C	.	.	H	α-helix	trans	-65.7	-39	173.1	-73.8	0	0	0	0	112.3	F17 F48 A49 M54 F55 E56	F17-C52 HydrophobicContact CB-CB 4.07Å; F17-C52 HydrophobicContact CD1-CB 3.9Å; F17-C52 HydrophobicContact CD2-CB 3.59Å; F17-C52 HydrophobicContact CE1-CB 4.21Å; F17-C52 HydrophobicContact CE2-CB 3.91Å; F17-C52 HydrophobicContact CG-CB 3.6Å; F17-C52 HydrophobicContact CZ-CB 4.22Å; F48-C52 VanDerWaalsContact CE1-SG 3.5Å; F48-C52 WeakPolarHBondContact CZ-SG 3.26Å; F48-C52 PolarHBondContact O-N 3.37Å; A49-C52 PolarHBondContact O-N 3.42Å; A49-C52 VanDerWaalsContact O-N 3.11Å; C52-M54 VanDerWaalsContact C-N 3.29Å; C52-M54 PolarHBondContact O-N 3.36Å; C52-F55 WeakPolarHBondContact O-CA 3.22Å; C52-F55 WeakPolarHBondContact O-CB 3.3Å; C52-F55 PolarHBondContact O-N 3.49Å; C52-E56 PolarHBondContact O-N 3.48Å
53	T	89.8	Confident	85.8	Confident	3 Å²	3	19 Å²	19	2%	0.018	10%	0.097	C	C	.	.	H	α-helix	trans	-64.5	-32.1	177.9	-55.5	0	0	0	0	112.3	M10 Q14 A49 F55 E56 L57 N78	M10-T53 HydrophobicContact CE-CG2 3.46Å; M10-T53 VanDerWaalsContact CE-CG2 3.46Å; Q14-T53 PolarHBondContact OE1-OG1 3.04Å; A49-T53 PolarHBondContact O-N 3.35Å; A49-T53 PolarHBondContact O-OG1 3.37Å; T53-F55 VanDerWaalsContact C-N 3.25Å; T53-F55 PolarHBondContact O-N 3.26Å; T53-E56 PolarHBondContact O-N 3.24Å; T53-L57 HydrophobicContact CG2-CD1 4.34Å; T53-L57 HydrophobicContact CG2-CG 4.44Å; T53-L57 WeakPolarHBondContact O-CB 3.47Å; T53-L57 VanDerWaalsContact O-CG 3.25Å; T53-L57 WeakPolarHBondContact O-CG 3.35Å; T53-L57 PolarHBondContact O-N 3.16Å; T53-N78 WeakPolarHBondContact CB-OD1 3.41Å; T53-N78 VanDerWaalsContact CG2-OD1 3.32Å; T53-N78 WeakPolarHBondContact CG2-OD1 3.47Å
54	M	84.6	Confident	85.2	Confident	3 Å²	3	20.5 Å²	20.5	2%	0.015	12%	0.117	C	C	.	.	H	α-helix	trans	-57.8	-39.7	169.7	-75	-62.8	-92.9	0	0	112	F50 S51 C52 I58 W75 N78 L79 I82 V372	F50-M54 PolarHBondContact O-N 3.19Å; F50-M54 VanDerWaalsContact O-N 3.17Å; S51-M54 PolarHBondContact O-N 2.99Å; C52-M54 VanDerWaalsContact C-N 3.29Å; C52-M54 PolarHBondContact O-N 3.36Å; M54-I58 WeakPolarHBondContact O-CG1 3.4Å; M54-I58 PolarHBondContact O-N 3.47Å; M54-W75 HydrophobicContact CE-CE3 4.25Å; M54-W75 HydrophobicContact CE-CZ3 3.62Å; M54-W75 HydrophobicContact SD-CE3 4.16Å; M54-W75 HydrophobicContact SD-CZ3 3.86Å; M54-N78 WeakPolarHBondContact CG-ND2 3.45Å; M54-N78 HydrophobicContact SD-CB 4.42Å; M54-N78 PolarHBondContact SD-ND2 3.08Å; M54-L79 HydrophobicContact CE-CB 4.47Å; M54-L79 HydrophobicContact CE-CD1 4.12Å; M54-L79 HydrophobicContact CE-CG 4.45Å; M54-I82 HydrophobicContact CG-CD1 4.49Å; M54-V372 HydrophobicContact CB-CG2 4.05Å; M54-V372 HydrophobicContact CE-CB 4.42Å; M54-V372 HydrophobicContact CE-CG1 3.99Å; M54-V372 HydrophobicContact CE-CG2 4.41Å
55	F	80.4	Confident	84.7	Confident	11 Å²	11	23.2 Å²	23.2	5%	0.048	13%	0.133	C	C	.	.	H	α-helix	trans	-76.7	-39.6	179.3	-70.9	-52.4	0	0	0	112.8	C52 T53 L57 I58 I59 I329 I333 F368 V372	C52-F55 WeakPolarHBondContact O-CA 3.22Å; C52-F55 WeakPolarHBondContact O-CB 3.3Å; C52-F55 PolarHBondContact O-N 3.49Å; T53-F55 VanDerWaalsContact C-N 3.25Å; T53-F55 PolarHBondContact O-N 3.26Å; F55-L57 PolarHBondContact O-N 3.17Å; F55-I58 HydrophobicContact CD1-CD1 3.91Å; F55-I58 HydrophobicContact CE1-CD1 4.45Å; F55-I58 WeakPolarHBondContact O-CB 3.3Å; F55-I58 PolarHBondContact O-N 2.91Å; F55-I58 VanDerWaalsContact O-N 3.11Å; F55-I59 WeakPolarHBondContact O-CG1 3.44Å; F55-I59 PolarHBondContact O-N 2.88Å; F55-I329 HydrophobicContact CB-CG2 4.44Å; F55-I329 HydrophobicContact CD1-CB 4.46Å; F55-I329 HydrophobicContact CD1-CD1 3.56Å; F55-I329 HydrophobicContact CD1-CG1 3.91Å; F55-I329 HydrophobicContact CD1-CG2 3.65Å; F55-I329 HydrophobicContact CD2-CG2 3.66Å; F55-I329 HydrophobicContact CE1-CB 4.33Å; F55-I329 HydrophobicContact CE1-CD1 3.82Å; F55-I329 HydrophobicContact CE1-CG1 3.67Å; F55-I329 HydrophobicContact CE1-CG2 3.67Å; F55-I329 HydrophobicContact CE2-CG2 3.58Å; F55-I329 HydrophobicContact CG-CD1 4.41Å; F55-I329 HydrophobicContact CG-CG2 3.68Å; F55-I329 HydrophobicContact CZ-CG1 4.25Å; F55-I329 HydrophobicContact CZ-CG2 3.63Å; F55-I333 HydrophobicContact CD2-CD1 3.74Å; F55-I333 HydrophobicContact CE2-CD1 3.5Å; F55-I333 VanDerWaalsContact CE2-CD1 3.5Å; F55-I333 HydrophobicContact CE2-CG1 3.93Å; F55-F368 AromaticContact CD2-CD1 3.56Å; F55-F368 HydrophobicContact CD2-CD1 3.56Å; F55-F368 AromaticContact CD2-CE1 3.64Å; F55-F368 HydrophobicContact CD2-CE1 3.64Å; F55-F368 AromaticContact CE2-CD1 2.98Å; F55-F368 HydrophobicContact CE2-CD1 2.98Å; F55-F368 AromaticContact CE2-CE1 3.25Å; F55-F368 HydrophobicContact CE2-CE1 3.25Å; F55-F368 AromaticContact CE2-CG 3.92Å; F55-F368 HydrophobicContact CE2-CG 3.92Å; F55-F368 HydrophobicContact CE2-CZ 4.31Å; F55-F368 AromaticContact CZ-CD1 3.84Å; F55-F368 HydrophobicContact CZ-CD1 3.84Å; F55-F368 HydrophobicContact CZ-CE1 4.4Å; F55-F368 HydrophobicContact CZ-CG 4.43Å; F55-V372 HydrophobicContact CD1-CG2 4.22Å; F55-V372 HydrophobicContact CE1-CG2 3.86Å; F55-V372 HydrophobicContact CZ-CG2 4.5Å
56	E	86.2	Confident	84.5	Confident	28 Å²	28	24.3 Å²	24.3	13%	0.131	14%	0.139	C	C	.	.	H	α-helix	trans	-57.1	-42.2	172.3	-176.1	-179.4	-147.3	0	0	111.2	S13 F17 C52 T53 I58 I59 F60	S13-E56 VanDerWaalsContact CB-CD 3.46Å; S13-E56 WeakPolarHBondContact CB-OE1 3.47Å; S13-E56 WeakPolarHBondContact CB-OE2 3.37Å; S13-E56 VanDerWaalsContact OG-CD 3.29Å; S13-E56 PolarHBondContact OG-OE1 3.46Å; S13-E56 PolarHBondContact OG-OE2 3.22Å; F17-E56 HydrophobicContact CE2-CB 4.11Å; F17-E56 WeakPolarHBondContact CE2-OE2 3.44Å; F17-E56 HydrophobicContact CZ-CB 4.33Å; C52-E56 PolarHBondContact O-N 3.48Å; T53-E56 PolarHBondContact O-N 3.24Å; E56-I58 VanDerWaalsContact C-N 3.3Å; E56-I58 PolarHBondContact O-N 3.22Å; E56-I59 CarbonylContact O-C 3.6Å; E56-I59 WeakPolarHBondContact O-CA 3.49Å; E56-I59 WeakPolarHBondContact O-CB 3.39Å; E56-I59 PolarHBondContact O-N 3.27Å; E56-I59 VanDerWaalsContact O-N 3.08Å; E56-F60 HydrophobicContact CG-CD2 4Å; E56-F60 HydrophobicContact CG-CE1 4.09Å; E56-F60 HydrophobicContact CG-CE2 3.49Å; E56-F60 VanDerWaalsContact CG-CE2 3.49Å; E56-F60 HydrophobicContact CG-CZ 3.54Å; E56-F60 WeakPolarHBondContact O-CG 3.42Å; E56-F60 PolarHBondContact O-N 3.43Å; E56-F60 VanDerWaalsContact OE1-CZ 3.23Å; E56-F60 WeakPolarHBondContact OE1-CZ 3.45Å
57	L	86.7	Confident	84.2	Confident	0 Å²	0	26.9 Å²	26.9	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-64	-31.7	176	-74.7	172.2	0	0	0	113.3	M10 T53 F55 E61 H74 W75 N78	M10-L57 HydrophobicContact CE-CD1 4.44Å; M10-L57 HydrophobicContact CE-CD2 3.58Å; M10-L57 HydrophobicContact CE-CG 3.85Å; M10-L57 HydrophobicContact SD-CD2 3.97Å; T53-L57 HydrophobicContact CG2-CD1 4.34Å; T53-L57 HydrophobicContact CG2-CG 4.44Å; T53-L57 WeakPolarHBondContact O-CB 3.47Å; T53-L57 VanDerWaalsContact O-CG 3.25Å; T53-L57 WeakPolarHBondContact O-CG 3.35Å; T53-L57 PolarHBondContact O-N 3.16Å; F55-L57 PolarHBondContact O-N 3.17Å; L57-E61 WeakPolarHBondContact O-CB 3.38Å; L57-E61 PolarHBondContact O-N 3.42Å; L57-H74 HydrophobicContact CD1-CB 4.47Å; L57-H74 HydrophobicContact CD2-CB 3.93Å; L57-W75 HydrophobicContact CB-CD2 4.16Å; L57-W75 HydrophobicContact CB-CZ2 3.83Å; L57-W75 HydrophobicContact CD1-CD2 4.22Å; L57-W75 HydrophobicContact CD1-CG 4.21Å; L57-N78 HydrophobicContact CD1-CB 4.01Å
58	I	80.4	Confident	83.9	Confident	2 Å²	2	30.1 Å²	30.1	1%	0.01	17%	0.174	C	C	.	.	H	α-helix	trans	-66.5	-44.3	170.5	-67.3	162.7	0	0	0	110.2	M54 F55 E56 F60 E61 I62 W75 V372 I375 M379	M54-I58 WeakPolarHBondContact O-CG1 3.4Å; M54-I58 PolarHBondContact O-N 3.47Å; F55-I58 HydrophobicContact CD1-CD1 3.91Å; F55-I58 HydrophobicContact CE1-CD1 4.45Å; F55-I58 WeakPolarHBondContact O-CB 3.3Å; F55-I58 PolarHBondContact O-N 2.91Å; F55-I58 VanDerWaalsContact O-N 3.11Å; E56-I58 VanDerWaalsContact C-N 3.3Å; E56-I58 PolarHBondContact O-N 3.22Å; I58-F60 VanDerWaalsContact C-N 3.33Å; I58-F60 PolarHBondContact O-N 2.81Å; I58-E61 WeakPolarHBondContact O-CB 3.49Å; I58-E61 PolarHBondContact O-N 3.37Å; I58-I62 HydrophobicContact CG2-CD1 3.71Å; I58-I62 HydrophobicContact CG2-CG1 4.49Å; I58-I62 VanDerWaalsContact O-CG1 3.31Å; I58-I62 WeakPolarHBondContact O-CG1 3.45Å; I58-I62 PolarHBondContact O-N 2.81Å; I58-W75 HydrophobicContact CB-CZ2 4.47Å; I58-W75 HydrophobicContact CD1-CH2 4.22Å; I58-W75 HydrophobicContact CG1-CH2 3.56Å; I58-W75 HydrophobicContact CG1-CZ2 3.59Å; I58-V372 HydrophobicContact CD1-CB 4.42Å; I58-V372 HydrophobicContact CD1-CG1 4.09Å; I58-V372 HydrophobicContact CD1-CG2 3.88Å; I58-I375 HydrophobicContact CD1-CD1 4.31Å; I58-I375 HydrophobicContact CD1-CG2 3.81Å; I58-M379 HydrophobicContact CG2-SD 4.02Å
59	I	79.4	Confident	83.9	Confident	69 Å²	69	34.7 Å²	34.7	35%	0.354	21%	0.207	S	C	.	.	H	α-helix	trans	-61.5	-44	178	-67.9	169.4	0	0	0	110.3	F55 E56 I62 L63 F322	F55-I59 WeakPolarHBondContact O-CG1 3.44Å; F55-I59 PolarHBondContact O-N 2.88Å; E56-I59 CarbonylContact O-C 3.6Å; E56-I59 WeakPolarHBondContact O-CA 3.49Å; E56-I59 WeakPolarHBondContact O-CB 3.39Å; E56-I59 PolarHBondContact O-N 3.27Å; E56-I59 VanDerWaalsContact O-N 3.08Å; I59-I62 PolarHBondContact O-N 3.17Å; I59-L63 HydrophobicContact CG2-CD1 3.61Å; I59-L63 HydrophobicContact CG2-CG 4.2Å; I59-L63 WeakPolarHBondContact O-CB 3.48Å; I59-L63 VanDerWaalsContact O-CG 3.32Å; I59-L63 WeakPolarHBondContact O-CG 3.4Å; I59-L63 PolarHBondContact O-N 3.09Å; I59-F322 HydrophobicContact CG1-CE2 4.27Å; I59-F322 HydrophobicContact CG1-CZ 4.5Å; I59-F322 HydrophobicContact CG2-CZ 4.2Å
60	F	85.3	Confident	83.8	Confident	26 Å²	26	34.8 Å²	34.8	11%	0.114	21%	0.208	C	C	.	.	H	α-helix	trans	-67.2	-33.9	177.2	-67.8	-16.7	0	0	0	113.2	I9 M10 E56 I58 G64 V65 L66	I9-F60 HydrophobicContact CG2-CZ 4.47Å; M10-F60 HydrophobicContact SD-CD2 3.84Å; M10-F60 HydrophobicContact SD-CE2 3.6Å; E56-F60 HydrophobicContact CG-CD2 4Å; E56-F60 HydrophobicContact CG-CE1 4.09Å; E56-F60 HydrophobicContact CG-CE2 3.49Å; E56-F60 VanDerWaalsContact CG-CE2 3.49Å; E56-F60 HydrophobicContact CG-CZ 3.54Å; E56-F60 WeakPolarHBondContact O-CG 3.42Å; E56-F60 PolarHBondContact O-N 3.43Å; E56-F60 VanDerWaalsContact OE1-CZ 3.23Å; E56-F60 WeakPolarHBondContact OE1-CZ 3.45Å; I58-F60 VanDerWaalsContact C-N 3.33Å; I58-F60 PolarHBondContact O-N 2.81Å; F60-G64 WeakPolarHBondContact O-CA 3.19Å; F60-G64 PolarHBondContact O-N 3.25Å; F60-V65 HydrophobicContact CB-CB 4.25Å; F60-V65 HydrophobicContact CD1-CB 3.84Å; F60-V65 HydrophobicContact CD1-CG1 3.9Å; F60-V65 HydrophobicContact CD1-CG2 4.46Å; F60-V65 HydrophobicContact CE1-CG1 4.13Å; F60-V65 HydrophobicContact CG-CB 4.2Å; F60-V65 HydrophobicContact CG-CG1 4.33Å; F60-V65 PolarHBondContact O-N 3.47Å; F60-L66 HydrophobicContact CB-CD1 4.49Å; F60-L66 HydrophobicContact CD2-CD1 3.5Å; F60-L66 HydrophobicContact CD2-CG 4.17Å; F60-L66 HydrophobicContact CE2-CD1 4.01Å; F60-L66 HydrophobicContact CG-CD1 4.27Å
61	E	80.9	Confident	83.6	Confident	12 Å²	12	33.7 Å²	33.7	6%	0.056	20%	0.202	C	C	.	.	H	α-helix	trans	-62.8	-44.3	172.6	-171.3	63.2	-162.6	0	0	111.4	L57 I58 G64 R71 Y383 I386	L57-E61 WeakPolarHBondContact O-CB 3.38Å; L57-E61 PolarHBondContact O-N 3.42Å; I58-E61 WeakPolarHBondContact O-CB 3.49Å; I58-E61 PolarHBondContact O-N 3.37Å; E61-G64 PolarHBondContact O-N 3.41Å; E61-R71 VanDerWaalsContact OE2-CD 3.32Å; E61-R71 WeakPolarHBondContact OE2-CD 3.44Å; E61-R71 IonicContact OE2-CZ 3.33Å; E61-R71 IonicContact OE2-NE 2.59Å; E61-R71 PolarHBondContact OE2-NE 2.86Å; E61-R71 IonicContact OE2-NH2 3.51Å; E61-Y383 WeakPolarHBondContact O-CD1 3.22Å; E61-I386 WeakPolarHBondContact OE2-CD1 3.32Å
62	I	74	Confident	83.5	Confident	21 Å²	21	37 Å²	37	11%	0.108	22%	0.216	C	C	.	.	H	α-helix	trans	-75.3	-40.1	-176.6	-62.4	167.1	0	0	0	111.8	I58 I59 G64 F322 M379	I58-I62 HydrophobicContact CG2-CD1 3.71Å; I58-I62 HydrophobicContact CG2-CG1 4.49Å; I58-I62 VanDerWaalsContact O-CG1 3.31Å; I58-I62 WeakPolarHBondContact O-CG1 3.45Å; I58-I62 PolarHBondContact O-N 2.81Å; I59-I62 PolarHBondContact O-N 3.17Å; I62-G64 PolarHBondContact O-N 2.95Å; I62-F322 HydrophobicContact CB-CD2 3.81Å; I62-F322 HydrophobicContact CB-CE2 3.88Å; I62-F322 HydrophobicContact CD1-CD2 3.39Å; I62-F322 HydrophobicContact CD1-CE2 3.83Å; I62-F322 HydrophobicContact CD1-CG 4.48Å; I62-F322 HydrophobicContact CG1-CD2 4.17Å; I62-F322 HydrophobicContact CG1-CE2 4.46Å; I62-F322 HydrophobicContact CG2-CB 4.02Å; I62-F322 HydrophobicContact CG2-CD1 4.47Å; I62-F322 HydrophobicContact CG2-CD2 3.38Å; I62-F322 HydrophobicContact CG2-CE2 3.84Å; I62-F322 HydrophobicContact CG2-CG 3.7Å; I62-M379 HydrophobicContact CD1-SD 3.72Å; I62-M379 HydrophobicContact CG1-SD 4.15Å
63	L	76.4	Confident	83.7	Confident	103 Å²	103	40.5 Å²	40.5	54%	0.539	23%	0.229	S	C	.	.	H	α-helix	trans	-78.2	-7.8	177.7	-64.6	179.9	0	0	0	113.1	I59 V65 F322	I59-L63 HydrophobicContact CG2-CD1 3.61Å; I59-L63 HydrophobicContact CG2-CG 4.2Å; I59-L63 WeakPolarHBondContact O-CB 3.48Å; I59-L63 VanDerWaalsContact O-CG 3.32Å; I59-L63 WeakPolarHBondContact O-CG 3.4Å; I59-L63 PolarHBondContact O-N 3.09Å; L63-V65 HydrophobicContact CB-CG2 3.67Å; L63-V65 PolarHBondContact O-N 2.91Å; L63-F322 HydrophobicContact CD1-CZ 4.5Å; L63-F322 HydrophobicContact CD2-CE1 4.01Å; L63-F322 HydrophobicContact CD2-CZ 4.07Å; L63-F322 HydrophobicContact CG-CZ 4.11Å
64	G	77.4	Confident	83.8	Confident	48 Å²	48	41.4 Å²	41.4	50%	0.495	23%	0.233	S	C	.	.	T	Hydrogen-bonded Turn	trans	65.5	24.5	-175.8	0	0	0	0	0	113.6	F60 E61 I62	F60-G64 WeakPolarHBondContact O-CA 3.19Å; F60-G64 PolarHBondContact O-N 3.25Å; E61-G64 PolarHBondContact O-N 3.41Å; I62-G64 PolarHBondContact O-N 2.95Å
65	V	78.2	Confident	84	Confident	58 Å²	58	41.4 Å²	41.4	35%	0.352	23%	0.232	S	C	.	.			trans	-80.6	145.1	178.7	-179.9	0	0	0	0	108.6	F60 L63 R71	F60-V65 HydrophobicContact CB-CB 4.25Å; F60-V65 HydrophobicContact CD1-CB 3.84Å; F60-V65 HydrophobicContact CD1-CG1 3.9Å; F60-V65 HydrophobicContact CD1-CG2 4.46Å; F60-V65 HydrophobicContact CE1-CG1 4.13Å; F60-V65 HydrophobicContact CG-CB 4.2Å; F60-V65 HydrophobicContact CG-CG1 4.33Å; F60-V65 PolarHBondContact O-N 3.47Å; L63-V65 HydrophobicContact CB-CG2 3.67Å; L63-V65 PolarHBondContact O-N 2.91Å; V65-R71 WeakPolarHBondContact O-CD 3.26Å; V65-R71 PolarHBondContact O-NH1 3.37Å
66	L	85	Confident	84.3	Confident	22 Å²	22	46.8 Å²	46.8	12%	0.115	26%	0.256	C	S	.	.	S	Bend	trans	69.7	161.3	-170.9	-46.7	172.1	0	0	0	114.4	D6 I9 M10 F60 R71	D6-L66 HydrophobicContact CB-CB 4.46Å; D6-L66 HydrophobicContact CB-CD2 3.68Å; I9-L66 HydrophobicContact CB-CD2 4.47Å; I9-L66 HydrophobicContact CD1-CD2 4.07Å; M10-L66 HydrophobicContact CG-CD1 4.12Å; M10-L66 HydrophobicContact SD-CD1 3.71Å; F60-L66 HydrophobicContact CB-CD1 4.49Å; F60-L66 HydrophobicContact CD2-CD1 3.5Å; F60-L66 HydrophobicContact CD2-CG 4.17Å; F60-L66 HydrophobicContact CE2-CD1 4.01Å; F60-L66 HydrophobicContact CG-CD1 4.27Å; L66-R71 HydrophobicContact CB-CG 3.89Å; L66-R71 HydrophobicContact CD1-CG 4.38Å; L66-R71 PolarHBondContact O-NH1 3.29Å
67	N	87.6	Confident	84.6	Confident	91 Å²	91	50 Å²	50	49%	0.487	27%	0.272	S	S	.	.			trans	-72.5	142.8	173.3	-88.9	-7.5	0	0	0	111.9	S2 D6 S69 S70 R71	S2-N67 WeakPolarHBondContact CB-ND2 3.47Å; S2-N67 VanDerWaalsContact OG-CG 3.24Å; S2-N67 PolarHBondContact OG-ND2 2.98Å; D6-N67 PolarHBondContact OD2-N 3.14Å; N67-S69 VanDerWaalsContact C-N 3.33Å; N67-S69 PolarHBondContact O-N 3.47Å; N67-S70 WeakPolarHBondContact O-CA 3.29Å; N67-S70 VanDerWaalsContact O-CB 3.28Å; N67-S70 WeakPolarHBondContact O-CB 3.48Å; N67-S70 PolarHBondContact O-N 3.4Å; N67-R71 PolarHBondContact O-N 3.15Å
68	S	84.5	Confident	84.8	Confident	69 Å²	69	50.3 Å²	50.3	48%	0.483	27%	0.274	S	S	.	.	H	α-helix	trans	-55.8	-42	-177.6	-52.5	0	0	0	0	113.6	S70 R71 Y72	S68-S70 VanDerWaalsContact C-N 3.3Å; S68-S70 PolarHBondContact O-N 3.31Å; S68-R71 PolarHBondContact O-N 3.44Å; S68-R71 PolarHBondContact OG-NH2 2.97Å; S68-Y72 PolarHBondContact O-N 3.42Å
69	S	86.6	Confident	85.1	Confident	102 Å²	102	51.2 Å²	51.2	71%	0.713	28%	0.278	S	S	*	.	H	α-helix	trans	-66	-33.3	176.2	-50.6	0	0	0	0	112.7	N67 F73	N67-S69 VanDerWaalsContact C-N 3.33Å; N67-S69 PolarHBondContact O-N 3.47Å; S69-F73 PolarHBondContact O-N 3.34Å
70	S	89.6	Confident	85.6	Confident	3 Å²	3	51.4 Å²	51.4	2%	0.021	29%	0.285	C	S	.	.	H	α-helix	trans	-70.6	-46	176	-164.6	0	0	0	0	110.7	D6 N67 S68 Y72 F73 H74	D6-S70 WeakPolarHBondContact CB-OG 3.32Å; D6-S70 WeakPolarHBondContact OD2-CB 3.39Å; D6-S70 PolarHBondContact OD2-OG 3.04Å; N67-S70 WeakPolarHBondContact O-CA 3.29Å; N67-S70 VanDerWaalsContact O-CB 3.28Å; N67-S70 WeakPolarHBondContact O-CB 3.48Å; N67-S70 PolarHBondContact O-N 3.4Å; S68-S70 VanDerWaalsContact C-N 3.3Å; S68-S70 PolarHBondContact O-N 3.31Å; S70-Y72 VanDerWaalsContact C-N 3.35Å; S70-Y72 PolarHBondContact O-N 3.29Å; S70-F73 PolarHBondContact O-N 2.83Å; S70-H74 PolarHBondContact O-CD2 3.1Å; S70-H74 PolarHBondContact O-N 2.91Å; S70-H74 PolarHBondContact OG-CD2 2.9Å; S70-H74 PolarHBondContact OG-NE2 3.49Å
71	R	88.4	Confident	85.9	Confident	19 Å²	19	52.4 Å²	52.4	7%	0.072	29%	0.293	C	S	.	.	H	α-helix	trans	-55.4	-48.9	174.5	-69.5	-160	-64.3	-95.5	-1.7	111.6	E61 V65 L66 N67 S68 F73 H74 W75 I386	E61-R71 VanDerWaalsContact OE2-CD 3.32Å; E61-R71 WeakPolarHBondContact OE2-CD 3.44Å; E61-R71 IonicContact OE2-CZ 3.33Å; E61-R71 IonicContact OE2-NE 2.59Å; E61-R71 PolarHBondContact OE2-NE 2.86Å; E61-R71 IonicContact OE2-NH2 3.51Å; V65-R71 WeakPolarHBondContact O-CD 3.26Å; V65-R71 PolarHBondContact O-NH1 3.37Å; L66-R71 HydrophobicContact CB-CG 3.89Å; L66-R71 HydrophobicContact CD1-CG 4.38Å; L66-R71 PolarHBondContact O-NH1 3.29Å; N67-R71 PolarHBondContact O-N 3.15Å; S68-R71 PolarHBondContact O-N 3.44Å; S68-R71 PolarHBondContact OG-NH2 2.97Å; R71-F73 VanDerWaalsContact C-N 3.34Å; R71-F73 PolarHBondContact O-N 2.87Å; R71-H74 PolarHBondContact O-N 3.31Å; R71-W75 WeakPolarHBondContact O-CB 3.43Å; R71-W75 VanDerWaalsContact O-CD1 3.25Å; R71-W75 PolarHBondContact O-N 3.03Å; R71-I386 HydrophobicContact CB-CD1 4.46Å
72	Y	86.6	Confident	86.3	Confident	70 Å²	70	51.9 Å²	51.9	28%	0.275	29%	0.291	S	S	.	.	H	α-helix	trans	-57	-46.4	177.8	178.3	-92.3	0	0	0	112.3	S68 S70 W75 K76 I386 E389 V390	S68-Y72 PolarHBondContact O-N 3.42Å; S70-Y72 VanDerWaalsContact C-N 3.35Å; S70-Y72 PolarHBondContact O-N 3.29Å; Y72-W75 PolarHBondContact O-N 2.95Å; Y72-K76 PolarHBondContact O-N 3.05Å; Y72-I386 HydrophobicContact CD2-CG2 4.23Å; Y72-E389 HydrophobicContact CE2-CB 4.27Å; Y72-E389 HydrophobicContact CE2-CG 3.89Å; Y72-V390 HydrophobicContact CD2-CG2 3.75Å; Y72-V390 HydrophobicContact CE2-CG2 3.67Å
73	F	90.4	Very high	86.8	Confident	90 Å²	90	51.5 Å²	51.5	40%	0.395	29%	0.289	S	S	.	.	H	α-helix	trans	-60.9	-49	177.1	175.8	-97.6	0	0	0	112	F3 S69 S70 R71 W75 K76 M77	F3-F73 HydrophobicContact CE2-CB 4.25Å; F3-F73 AromaticContact CE2-CD1 3.74Å; F3-F73 HydrophobicContact CE2-CD1 3.74Å; F3-F73 HydrophobicContact CE2-CE1 4.36Å; F3-F73 HydrophobicContact CE2-CG 4.09Å; F3-F73 AromaticContact CZ-CD1 3.6Å; F3-F73 HydrophobicContact CZ-CD1 3.6Å; F3-F73 AromaticContact CZ-CE1 3.75Å; F3-F73 HydrophobicContact CZ-CE1 3.75Å; F3-F73 HydrophobicContact CZ-CG 4.17Å; F3-F73 HydrophobicContact CZ-CZ 4.43Å; S69-F73 PolarHBondContact O-N 3.34Å; S70-F73 PolarHBondContact O-N 2.83Å; R71-F73 VanDerWaalsContact C-N 3.34Å; R71-F73 PolarHBondContact O-N 2.87Å; F73-W75 PolarHBondContact O-N 2.94Å; F73-K76 PolarHBondContact O-N 2.94Å; F73-M77 HydrophobicContact CD1-CG 4.19Å; F73-M77 HydrophobicContact CD2-CG 4.31Å; F73-M77 HydrophobicContact CE1-CG 3.74Å; F73-M77 HydrophobicContact CE2-CG 3.87Å; F73-M77 HydrophobicContact CE2-SD 4.36Å; F73-M77 HydrophobicContact CG-CG 4.46Å; F73-M77 HydrophobicContact CZ-CG 3.57Å; F73-M77 HydrophobicContact CZ-SD 4.11Å; F73-M77 WeakPolarHBondContact O-CB 3.45Å; F73-M77 WeakPolarHBondContact O-CG 2.89Å; F73-M77 PolarHBondContact O-N 3.37Å
74	H	91.4	Very high	87.5	Confident	23 Å²	23	50.6 Å²	50.6	11%	0.106	28%	0.284	C	S	.	.	H	α-helix	trans	-65.2	-37.6	179.9	-72.9	-64.6	0	0	0	112.5	L57 S70 R71 N78	L57-H74 HydrophobicContact CD1-CB 4.47Å; L57-H74 HydrophobicContact CD2-CB 3.93Å; S70-H74 PolarHBondContact O-CD2 3.1Å; S70-H74 PolarHBondContact O-N 2.91Å; S70-H74 PolarHBondContact OG-CD2 2.9Å; S70-H74 PolarHBondContact OG-NE2 3.49Å; R71-H74 PolarHBondContact O-N 3.31Å; H74-N78 WeakPolarHBondContact O-CB 3.45Å; H74-N78 PolarHBondContact O-N 3.33Å
75	W	88.7	Confident	88	Confident	2 Å²	2	49 Å²	49	1%	0.008	26%	0.264	C	S	.	.	H	α-helix	trans	-57.9	-52	171.7	-94.9	107.2	0	0	0	112	M54 L57 I58 R71 Y72 F73 M77 N78 L79 V372 I386 I387 V390	M54-W75 HydrophobicContact CE-CE3 4.25Å; M54-W75 HydrophobicContact CE-CZ3 3.62Å; M54-W75 HydrophobicContact SD-CE3 4.16Å; M54-W75 HydrophobicContact SD-CZ3 3.86Å; L57-W75 HydrophobicContact CB-CD2 4.16Å; L57-W75 HydrophobicContact CB-CZ2 3.83Å; L57-W75 HydrophobicContact CD1-CD2 4.22Å; L57-W75 HydrophobicContact CD1-CG 4.21Å; I58-W75 HydrophobicContact CB-CZ2 4.47Å; I58-W75 HydrophobicContact CD1-CH2 4.22Å; I58-W75 HydrophobicContact CG1-CH2 3.56Å; I58-W75 HydrophobicContact CG1-CZ2 3.59Å; R71-W75 WeakPolarHBondContact O-CB 3.43Å; R71-W75 VanDerWaalsContact O-CD1 3.25Å; R71-W75 PolarHBondContact O-N 3.03Å; Y72-W75 PolarHBondContact O-N 2.95Å; F73-W75 PolarHBondContact O-N 2.94Å; W75-M77 PolarHBondContact O-N 3.44Å; W75-N78 PolarHBondContact O-N 2.85Å; W75-L79 VanDerWaalsContact O-CB 3.23Å; W75-L79 WeakPolarHBondContact O-CB 3.47Å; W75-L79 PolarHBondContact O-N 2.98Å; W75-V372 HydrophobicContact CH2-CG1 3.91Å; W75-V372 HydrophobicContact CZ3-CG1 3.99Å; W75-I386 HydrophobicContact CG-CG2 4.32Å; W75-I387 HydrophobicContact CH2-CD1 4.11Å; W75-I387 HydrophobicContact CH2-CG1 4.02Å; W75-I387 HydrophobicContact CZ2-CD1 3.85Å; W75-I387 HydrophobicContact CZ2-CG1 3.77Å; W75-V390 HydrophobicContact CB-CG1 4.3Å; W75-V390 HydrophobicContact CB-CG2 4Å
76	K	87.4	Confident	88.5	Confident	125 Å²	125	46.2 Å²	46.2	54%	0.543	25%	0.247	S	C	.	.	H	α-helix	trans	-63	-44	-179.8	-173.1	173.5	-177.8	172.4	0	111.9	Y72 F73 C80	Y72-K76 PolarHBondContact O-N 3.05Å; F73-K76 PolarHBondContact O-N 2.94Å; K76-C80 VanDerWaalsContact O-CB 3.25Å; K76-C80 WeakPolarHBondContact O-CB 3.42Å; K76-C80 PolarHBondContact O-N 2.87Å
77	M	90.7	Very high	88.5	Confident	94 Å²	94	46.3 Å²	46.3	46%	0.463	25%	0.249	S	C	.	.	H	α-helix	trans	-62.9	-49.7	177.1	-77.5	-66.9	-69.1	0	0	111.9	F73 W75 L79 C80 V81	F73-M77 HydrophobicContact CD1-CG 4.19Å; F73-M77 HydrophobicContact CD2-CG 4.31Å; F73-M77 HydrophobicContact CE1-CG 3.74Å; F73-M77 HydrophobicContact CE2-CG 3.87Å; F73-M77 HydrophobicContact CE2-SD 4.36Å; F73-M77 HydrophobicContact CG-CG 4.46Å; F73-M77 HydrophobicContact CZ-CG 3.57Å; F73-M77 HydrophobicContact CZ-SD 4.11Å; F73-M77 WeakPolarHBondContact O-CB 3.45Å; F73-M77 WeakPolarHBondContact O-CG 2.89Å; F73-M77 PolarHBondContact O-N 3.37Å; W75-M77 PolarHBondContact O-N 3.44Å; M77-L79 PolarHBondContact O-N 3.46Å; M77-C80 PolarHBondContact O-N 3.31Å; M77-V81 WeakPolarHBondContact O-CG2 3.5Å; M77-V81 PolarHBondContact O-N 2.92Å
78	N	91.9	Very high	88.4	Confident	8 Å²	8	46.7 Å²	46.7	4%	0.043	25%	0.246	C	C	.	.	H	α-helix	trans	-63.2	-44.1	-177.8	-166.6	83.6	0	0	0	111.2	F50 T53 M54 L57 H74 W75 V81 I82	F50-N78 WeakPolarHBondContact CD1-OD1 3.42Å; F50-N78 PolarHBondContact O-ND2 3.14Å; T53-N78 WeakPolarHBondContact CB-OD1 3.41Å; T53-N78 VanDerWaalsContact CG2-OD1 3.32Å; T53-N78 WeakPolarHBondContact CG2-OD1 3.47Å; M54-N78 WeakPolarHBondContact CG-ND2 3.45Å; M54-N78 HydrophobicContact SD-CB 4.42Å; M54-N78 PolarHBondContact SD-ND2 3.08Å; L57-N78 HydrophobicContact CD1-CB 4.01Å; H74-N78 WeakPolarHBondContact O-CB 3.45Å; H74-N78 PolarHBondContact O-N 3.33Å; W75-N78 PolarHBondContact O-N 2.85Å; N78-V81 PolarHBondContact O-N 3.49Å; N78-I82 WeakPolarHBondContact O-CG2 3.37Å; N78-I82 PolarHBondContact O-N 3.22Å
79	L	86.9	Confident	88.6	Confident	20 Å²	20	47.3 Å²	47.3	11%	0.105	24%	0.243	C	C	.	.	H	α-helix	trans	-64	-41	176.8	-168.3	147.5	0	0	0	111.8	M54 W75 M77 I82 L83 V390 L391	M54-L79 HydrophobicContact CE-CB 4.47Å; M54-L79 HydrophobicContact CE-CD1 4.12Å; M54-L79 HydrophobicContact CE-CG 4.45Å; W75-L79 VanDerWaalsContact O-CB 3.23Å; W75-L79 WeakPolarHBondContact O-CB 3.47Å; W75-L79 PolarHBondContact O-N 2.98Å; M77-L79 PolarHBondContact O-N 3.46Å; L79-I82 WeakPolarHBondContact O-CG2 3.34Å; L79-L83 HydrophobicContact CD2-CD1 3.43Å; L79-L83 VanDerWaalsContact CD2-CD1 3.43Å; L79-L83 HydrophobicContact CD2-CG 4.21Å; L79-L83 HydrophobicContact CG-CD1 4.35Å; L79-L83 WeakPolarHBondContact O-CB 3.36Å; L79-L83 WeakPolarHBondContact O-CG 3.5Å; L79-L83 PolarHBondContact O-N 3.45Å; L79-L83 VanDerWaalsContact O-N 3.1Å; L79-V390 HydrophobicContact CD1-CG1 4.18Å; L79-L391 HydrophobicContact CD1-CD2 3.72Å
80	C	89	Confident	88.7	Confident	74 Å²	74	42.5 Å²	42.5	50%	0.5	21%	0.209	S	C	.	.	H	α-helix	trans	-61.4	-48.2	175	-176.7	0	0	0	0	111.9	K76 M77 L83 L84	K76-C80 VanDerWaalsContact O-CB 3.25Å; K76-C80 WeakPolarHBondContact O-CB 3.42Å; K76-C80 PolarHBondContact O-N 2.87Å; M77-C80 PolarHBondContact O-N 3.31Å; C80-L83 PolarHBondContact O-N 3.34Å; C80-L84 WeakPolarHBondContact O-CB 3.48Å; C80-L84 PolarHBondContact O-N 3.45Å
81	V	91.6	Very high	88.6	Confident	46 Å²	46	44.8 Å²	44.8	28%	0.279	22%	0.223	S	C	.	.	H	α-helix	trans	-66.9	-45.4	-177.6	175.3	0	0	0	0	111.5	F50 M77 N78 L83 L84 I85	F50-V81 HydrophobicContact CD1-CB 3.99Å; F50-V81 HydrophobicContact CD1-CG1 3.82Å; F50-V81 HydrophobicContact CD2-CG1 4.05Å; F50-V81 HydrophobicContact CE1-CB 3.69Å; F50-V81 HydrophobicContact CE1-CG1 3.49Å; F50-V81 VanDerWaalsContact CE1-CG1 3.49Å; F50-V81 HydrophobicContact CE1-CG2 4.19Å; F50-V81 HydrophobicContact CE2-CG1 3.7Å; F50-V81 HydrophobicContact CG-CG1 4.14Å; F50-V81 HydrophobicContact CZ-CB 4.13Å; F50-V81 HydrophobicContact CZ-CG1 3.44Å; F50-V81 VanDerWaalsContact CZ-CG1 3.44Å; F50-V81 HydrophobicContact CZ-CG2 4.48Å; M77-V81 WeakPolarHBondContact O-CG2 3.5Å; M77-V81 PolarHBondContact O-N 2.92Å; N78-V81 PolarHBondContact O-N 3.49Å; V81-L83 VanDerWaalsContact C-N 3.31Å; V81-L83 PolarHBondContact O-N 2.95Å; V81-L84 PolarHBondContact O-N 3.32Å; V81-I85 HydrophobicContact CG1-CD1 3.73Å; V81-I85 HydrophobicContact CG1-CG1 4.41Å; V81-I85 WeakPolarHBondContact O-CD1 3.36Å; V81-I85 VanDerWaalsContact O-CG1 3.27Å; V81-I85 WeakPolarHBondContact O-CG1 3.37Å; V81-I85 PolarHBondContact O-N 3.28Å
82	I	89.8	Confident	88.5	Confident	1 Å²	1	50.4 Å²	50.4	1%	0.005	25%	0.249	C	C	.	.	H	α-helix	trans	-64.6	-36.4	179.2	-162.8	166.9	0	0	0	111.8	F50 S51 M54 N78 L79 I85 L86 V369	F50-I82 HydrophobicContact CB-CB 4.27Å; F50-I82 HydrophobicContact CB-CD1 4.33Å; F50-I82 HydrophobicContact CB-CG1 4.39Å; S51-I82 WeakPolarHBondContact OG-CD1 3.46Å; M54-I82 HydrophobicContact CG-CD1 4.49Å; N78-I82 WeakPolarHBondContact O-CG2 3.37Å; N78-I82 PolarHBondContact O-N 3.22Å; L79-I82 WeakPolarHBondContact O-CG2 3.34Å; I82-I85 PolarHBondContact O-N 3.45Å; I82-L86 HydrophobicContact CG1-CD1 4.05Å; I82-L86 HydrophobicContact CG1-CG 4.42Å; I82-L86 WeakPolarHBondContact O-CB 3.23Å; I82-L86 VanDerWaalsContact O-CG 3.29Å; I82-L86 WeakPolarHBondContact O-CG 3.37Å; I82-L86 PolarHBondContact O-N 3.31Å; I82-V369 HydrophobicContact CD1-CG2 4.06Å; I82-V369 HydrophobicContact CG1-CG2 4.35Å; I82-V369 HydrophobicContact CG2-CG2 4.16Å
83	L	85.4	Confident	88.4	Confident	14 Å²	14	49.8 Å²	49.8	7%	0.073	25%	0.246	C	C	.	.	H	α-helix	trans	-66.5	-43.5	173.8	-73.9	177.2	0	0	0	111.9	L79 C80 V81 I85 L86 V87 I124	L79-L83 HydrophobicContact CD2-CD1 3.43Å; L79-L83 VanDerWaalsContact CD2-CD1 3.43Å; L79-L83 HydrophobicContact CD2-CG 4.21Å; L79-L83 HydrophobicContact CG-CD1 4.35Å; L79-L83 WeakPolarHBondContact O-CB 3.36Å; L79-L83 WeakPolarHBondContact O-CG 3.5Å; L79-L83 PolarHBondContact O-N 3.45Å; L79-L83 VanDerWaalsContact O-N 3.1Å; C80-L83 PolarHBondContact O-N 3.34Å; V81-L83 VanDerWaalsContact C-N 3.31Å; V81-L83 PolarHBondContact O-N 2.95Å; L83-I85 VanDerWaalsContact C-N 3.26Å; L83-I85 PolarHBondContact O-N 2.93Å; L83-L86 PolarHBondContact O-N 2.96Å; L83-V87 VanDerWaalsContact O-CB 3.22Å; L83-V87 WeakPolarHBondContact O-CB 3.46Å; L83-V87 WeakPolarHBondContact O-CG2 3.26Å; L83-V87 PolarHBondContact O-N 2.99Å; L83-I124 HydrophobicContact CD1-CD1 3.9Å; L83-I124 HydrophobicContact CD1-CG1 3.52Å; L83-I124 HydrophobicContact CD2-CG1 4.18Å
84	L	89.4	Confident	88	Confident	83 Å²	83	46.5 Å²	46.5	44%	0.435	23%	0.233	S	C	.	.	H	α-helix	trans	-57.4	-45.4	176	-170.1	168	0	0	0	110.4	C80 V81 F88 M89	C80-L84 WeakPolarHBondContact O-CB 3.48Å; C80-L84 PolarHBondContact O-N 3.45Å; V81-L84 PolarHBondContact O-N 3.32Å; L84-F88 HydrophobicContact CG-CD2 4.48Å; L84-F88 WeakPolarHBondContact O-CB 3.38Å; L84-F88 PolarHBondContact O-N 3.42Å; L84-M89 HydrophobicContact CD2-CG 3.68Å; L84-M89 PolarHBondContact O-N 3.47Å
85	I	89.7	Confident	87.2	Confident	14 Å²	14	46.9 Å²	46.9	7%	0.072	24%	0.243	C	C	.	.	I	π-helix	trans	-61.4	-50.2	178.1	-67.6	162.4	0	0	0	111.2	V46 T47 F50 V81 I82 L83 M89 V90	V46-I85 HydrophobicContact CG1-CD1 3.57Å; T47-I85 HydrophobicContact CG2-CG2 4.49Å; T47-I85 VanDerWaalsContact OG1-CG2 3.27Å; T47-I85 WeakPolarHBondContact OG1-CG2 3.33Å; F50-I85 HydrophobicContact CD2-CD1 4.07Å; V81-I85 HydrophobicContact CG1-CD1 3.73Å; V81-I85 HydrophobicContact CG1-CG1 4.41Å; V81-I85 WeakPolarHBondContact O-CD1 3.36Å; V81-I85 VanDerWaalsContact O-CG1 3.27Å; V81-I85 WeakPolarHBondContact O-CG1 3.37Å; V81-I85 PolarHBondContact O-N 3.28Å; I82-I85 PolarHBondContact O-N 3.45Å; L83-I85 VanDerWaalsContact C-N 3.26Å; L83-I85 PolarHBondContact O-N 2.93Å; I85-M89 PolarHBondContact O-N 2.85Å; I85-V90 HydrophobicContact CG2-CG2 3.79Å; I85-V90 WeakPolarHBondContact O-CG2 3.35Å; I85-V90 PolarHBondContact O-N 3.39Å
86	L	88.4	Confident	86.8	Confident	0 Å²	0	53 Å²	53	0%	0	27%	0.267	C	S	.	.	I	π-helix	trans	-73.6	-27.3	-174.8	-71.8	175.4	0	0	0	114.4	T47 I82 L83 P91 V127 Q362 G365 V369	T47-L86 HydrophobicContact CG2-CD2 4.22Å; I82-L86 HydrophobicContact CG1-CD1 4.05Å; I82-L86 HydrophobicContact CG1-CG 4.42Å; I82-L86 WeakPolarHBondContact O-CB 3.23Å; I82-L86 VanDerWaalsContact O-CG 3.29Å; I82-L86 WeakPolarHBondContact O-CG 3.37Å; I82-L86 PolarHBondContact O-N 3.31Å; L83-L86 PolarHBondContact O-N 2.96Å; L86-P91 VanDerWaalsContact O-CD 3.31Å; L86-P91 WeakPolarHBondContact O-CD 3.48Å; L86-P91 VanDerWaalsContact O-CG 3.32Å; L86-P91 WeakPolarHBondContact O-CG 3.23Å; L86-V127 HydrophobicContact CB-CG1 4.42Å; L86-V127 HydrophobicContact CD1-CG1 4.28Å; L86-Q362 PolarHBondContact O-NE2 2.79Å; L86-Q362 PolarHBondContact O-OE1 2.75Å; L86-Q362 VanDerWaalsContact O-OE1 3.05Å; L86-G365 VanDerWaalsContact CD1-C 3.41Å; L86-V369 HydrophobicContact CD1-CG2 3.93Å
87	V	84.3	Confident	85.9	Confident	24 Å²	24	47.7 Å²	47.7	15%	0.145	24%	0.244	C	C	.	.	I	π-helix	trans	-91.9	-46.5	-177.2	170.9	0	0	0	0	111	L83 P91 L123 V127	L83-V87 VanDerWaalsContact O-CB 3.22Å; L83-V87 WeakPolarHBondContact O-CB 3.46Å; L83-V87 WeakPolarHBondContact O-CG2 3.26Å; L83-V87 PolarHBondContact O-N 2.99Å; V87-P91 VanDerWaalsContact O-CG 3.26Å; V87-P91 WeakPolarHBondContact O-CG 3.32Å; V87-L123 HydrophobicContact CB-CD1 4.03Å; V87-L123 HydrophobicContact CB-CD2 3.99Å; V87-L123 HydrophobicContact CB-CG 4.12Å; V87-L123 HydrophobicContact CG1-CD1 3.17Å; V87-L123 HydrophobicContact CG1-CD2 3.64Å; V87-L123 HydrophobicContact CG1-CG 3.72Å; V87-L123 HydrophobicContact CG2-CD1 3.69Å; V87-L123 HydrophobicContact CG2-CD2 3.66Å; V87-L123 HydrophobicContact CG2-CG 3.44Å; V87-L123 VanDerWaalsContact CG2-CG 3.44Å; V87-V127 HydrophobicContact CG2-CG2 3.56Å
88	F	86.3	Confident	84.8	Confident	99 Å²	99	46.6 Å²	46.6	43%	0.434	24%	0.239	S	C	.	.	I	π-helix	trans	-104.1	-58.7	-168.8	-63.2	-73.6	0	0	0	110.5	L84 F92 L118 L123	L84-F88 HydrophobicContact CG-CD2 4.48Å; L84-F88 WeakPolarHBondContact O-CB 3.38Å; L84-F88 PolarHBondContact O-N 3.42Å; F88-F92 WeakPolarHBondContact O-CB 3.45Å; F88-F92 PolarHBondContact O-N 3.35Å; F88-L118 HydrophobicContact CE1-CD2 4.17Å; F88-L118 HydrophobicContact CZ-CD2 3.66Å; F88-L123 HydrophobicContact CE2-CD2 3.95Å; F88-L123 HydrophobicContact CZ-CD2 4.19Å
89	M	88.3	Confident	83.5	Confident	83 Å²	83	50.7 Å²	50.7	41%	0.409	26%	0.264	S	S	.	.	I	π-helix	trans	-65.2	-57.9	-170.3	-64.9	-73.9	-106.2	0	0	111.8	L84 I85 F92 Y93	L84-M89 HydrophobicContact CD2-CG 3.68Å; L84-M89 PolarHBondContact O-N 3.47Å; I85-M89 PolarHBondContact O-N 2.85Å; M89-F92 PolarHBondContact O-N 2.91Å; M89-Y93 WeakPolarHBondContact O-CD2 3.46Å; M89-Y93 PolarHBondContact O-N 3.16Å; M89-Y93 HydrophobicContact SD-CE2 4.46Å
90	V	87.9	Confident	82.3	Confident	0 Å²	0	52.5 Å²	52.5	0%	0	28%	0.279	C	S	.	.	H	α-helix	trans	-62.1	-49	-174.6	175.3	0	0	0	0	111.5	I43 I85 F92 Y93 I94 L358 Q362	I43-V90 HydrophobicContact CG2-CG2 3.57Å; I85-V90 HydrophobicContact CG2-CG2 3.79Å; I85-V90 WeakPolarHBondContact O-CG2 3.35Å; I85-V90 PolarHBondContact O-N 3.39Å; V90-F92 VanDerWaalsContact C-N 3.35Å; V90-F92 PolarHBondContact O-N 3.44Å; V90-Y93 PolarHBondContact O-N 3.06Å; V90-I94 HydrophobicContact CG1-CD1 3.74Å; V90-I94 HydrophobicContact CG1-CG1 4.36Å; V90-I94 VanDerWaalsContact O-CG1 3.28Å; V90-I94 WeakPolarHBondContact O-CG1 3.47Å; V90-I94 PolarHBondContact O-N 2.82Å; V90-L358 HydrophobicContact CG1-CB 4.43Å; V90-L358 VanDerWaalsContact CG1-O 3.28Å; V90-L358 WeakPolarHBondContact CG1-O 3.38Å; V90-Q362 VanDerWaalsContact CB-OE1 3.28Å; V90-Q362 HydrophobicContact CG1-CB 3.77Å; V90-Q362 HydrophobicContact CG1-CG 4.42Å
91	P	87.1	Confident	80.7	Confident	51 Å²	51	52.7 Å²	52.7	33%	0.331	27%	0.274	S	S	.	.	H	α-helix	trans	-62.7	-36.6	176.4	-27.4	40.1	0	0	0	113.9	L86 V87 I94 G95	L86-P91 VanDerWaalsContact O-CD 3.31Å; L86-P91 WeakPolarHBondContact O-CD 3.48Å; L86-P91 VanDerWaalsContact O-CG 3.32Å; L86-P91 WeakPolarHBondContact O-CG 3.23Å; V87-P91 VanDerWaalsContact O-CG 3.26Å; V87-P91 WeakPolarHBondContact O-CG 3.32Å; P91-I94 PolarHBondContact O-N 3.23Å; P91-G95 PolarHBondContact O-N 3.39Å
92	F	87.1	Confident	78.8	Confident	137 Å²	137	54.3 Å²	54.3	60%	0.601	28%	0.281	S	S	*	.	H	α-helix	trans	-60.7	-47.7	174.4	174.1	-96.2	0	0	0	111.5	F88 M89 V90 G95 Y96	F88-F92 WeakPolarHBondContact O-CB 3.45Å; F88-F92 PolarHBondContact O-N 3.35Å; M89-F92 PolarHBondContact O-N 2.91Å; V90-F92 VanDerWaalsContact C-N 3.35Å; V90-F92 PolarHBondContact O-N 3.44Å; F92-G95 PolarHBondContact O-N 2.96Å; F92-Y96 WeakPolarHBondContact O-CB 3.49Å; F92-Y96 PolarHBondContact O-N 3.09Å
93	Y	85	Confident	76.6	Confident	58 Å²	58	65.1 Å²	65.1	23%	0.227	32%	0.322	C	S	.	.	H	α-helix	trans	-67.9	-36.7	178.1	-79.2	-75	0	0	0	112.3	V39 I43 M89 V90 Y96 F97	V39-Y93 HydrophobicContact CG1-CD1 4.18Å; V39-Y93 HydrophobicContact CG1-CE1 3.56Å; V39-Y93 HydrophobicContact CG1-CE2 4.41Å; I43-Y93 HydrophobicContact CD1-CD1 4.23Å; I43-Y93 HydrophobicContact CD1-CD2 3.22Å; I43-Y93 HydrophobicContact CD1-CE1 4.42Å; I43-Y93 HydrophobicContact CD1-CE2 3.47Å; I43-Y93 VanDerWaalsContact CD1-CE2 3.47Å; I43-Y93 HydrophobicContact CD1-CG 3.65Å; I43-Y93 HydrophobicContact CG1-CD2 4.46Å; I43-Y93 HydrophobicContact CG1-CE2 4.5Å; M89-Y93 WeakPolarHBondContact O-CD2 3.46Å; M89-Y93 PolarHBondContact O-N 3.16Å; M89-Y93 HydrophobicContact SD-CE2 4.46Å; V90-Y93 PolarHBondContact O-N 3.06Å; Y93-Y96 PolarHBondContact O-N 3.46Å; Y93-F97 HydrophobicContact CD1-CE2 4.39Å; Y93-F97 WeakPolarHBondContact O-CD2 3.43Å; Y93-F97 PolarHBondContact O-N 3.11Å
94	I	81.7	Confident	74.8	Confident	21 Å²	21	71.9 Å²	71.9	11%	0.108	36%	0.357	C	S	.	.	H	α-helix	trans	-57.9	-50.5	171.8	-70	165.7	0	0	0	109.9	V90 P91 Y96 F97 I98 V355 L358 L359	V90-I94 HydrophobicContact CG1-CD1 3.74Å; V90-I94 HydrophobicContact CG1-CG1 4.36Å; V90-I94 VanDerWaalsContact O-CG1 3.28Å; V90-I94 WeakPolarHBondContact O-CG1 3.47Å; V90-I94 PolarHBondContact O-N 2.82Å; P91-I94 PolarHBondContact O-N 3.23Å; I94-Y96 PolarHBondContact O-N 2.87Å; I94-F97 PolarHBondContact O-N 3.38Å; I94-I98 HydrophobicContact CG2-CD1 3.54Å; I94-I98 HydrophobicContact CG2-CG1 4.31Å; I94-I98 WeakPolarHBondContact O-CB 3.34Å; I94-I98 VanDerWaalsContact O-CG1 3.23Å; I94-I98 WeakPolarHBondContact O-CG1 3.37Å; I94-I98 PolarHBondContact O-N 3Å; I94-V355 HydrophobicContact CG2-CG1 4.47Å; I94-L358 HydrophobicContact CD1-CB 4.16Å; I94-L358 HydrophobicContact CG1-CB 3.51Å; I94-L358 HydrophobicContact CG1-CD1 4.27Å; I94-L359 HydrophobicContact CD1-CD2 3.89Å; I94-L359 HydrophobicContact CD1-CG 4.25Å
95	G	74.8	Confident	72.3	Confident	31 Å²	31	77.9 Å²	77.9	32%	0.32	37%	0.374	S	S	.	.	H	α-helix	trans	-59.2	-45.8	177	0	0	0	0	0	112.4	P91 F92 F97 I98 V99	P91-G95 PolarHBondContact O-N 3.39Å; F92-G95 PolarHBondContact O-N 2.96Å; G95-F97 PolarHBondContact O-N 3.4Å; G95-I98 PolarHBondContact O-N 3.32Å; G95-V99 WeakPolarHBondContact O-CB 3.2Å; G95-V99 VanDerWaalsContact O-CG2 3.26Å; G95-V99 WeakPolarHBondContact O-CG2 3.46Å; G95-V99 PolarHBondContact O-N 3.36Å
96	Y	80.1	Confident	69.7	Low	130 Å²	130	83.7 Å²	83.7	51%	0.51	41%	0.405	S	S	.	.	H	α-helix	trans	-56.9	-47.7	175.7	174.3	-95.9	0	0	0	112.1	F92 Y93 I94 V99 S100	F92-Y96 WeakPolarHBondContact O-CB 3.49Å; F92-Y96 PolarHBondContact O-N 3.09Å; Y93-Y96 PolarHBondContact O-N 3.46Å; I94-Y96 PolarHBondContact O-N 2.87Å; Y96-V99 PolarHBondContact O-N 2.93Å; Y96-S100 WeakPolarHBondContact O-CB 3.44Å; Y96-S100 PolarHBondContact O-N 3.31Å
97	F	69.4	Low	67.2	Low	14 Å²	14	89.4 Å²	89.4	6%	0.061	44%	0.442	C	S	.	.	H	α-helix	trans	-70	-37.7	179.6	-82.5	-65.4	0	0	0	113.2	V40 Y93 I94 G95 S100 N101 N354 V355 L358	V40-F97 HydrophobicContact CG2-CE2 3.67Å; V40-F97 HydrophobicContact CG2-CZ 3.98Å; Y93-F97 HydrophobicContact CD1-CE2 4.39Å; Y93-F97 WeakPolarHBondContact O-CD2 3.43Å; Y93-F97 PolarHBondContact O-N 3.11Å; I94-F97 PolarHBondContact O-N 3.38Å; G95-F97 PolarHBondContact O-N 3.4Å; F97-S100 PolarHBondContact O-N 3.46Å; F97-N101 VanDerWaalsContact O-CB 3.25Å; F97-N101 WeakPolarHBondContact O-CB 3.47Å; F97-N101 VanDerWaalsContact O-CG 3.23Å; F97-N101 PolarHBondContact O-N 3Å; F97-N101 PolarHBondContact O-ND2 3.49Å; F97-N354 HydrophobicContact CD1-CB 4.42Å; F97-N354 HydrophobicContact CE1-CB 4.48Å; F97-V355 HydrophobicContact CB-CG2 3.51Å; F97-V355 HydrophobicContact CG-CG2 4.47Å; F97-L358 HydrophobicContact CD2-CD1 3.47Å; F97-L358 VanDerWaalsContact CD2-CD1 3.47Å; F97-L358 HydrophobicContact CE2-CD1 3.9Å
98	I	66.6	Low	64.5	Low	70 Å²	70	97.8 Å²	97.8	36%	0.359	48%	0.477	S	S	.	.	H	α-helix	trans	-63.1	-49.8	174.4	-71.2	173.8	0	0	0	109.6	I94 G95 S100 N101 I102 V355	I94-I98 HydrophobicContact CG2-CD1 3.54Å; I94-I98 HydrophobicContact CG2-CG1 4.31Å; I94-I98 WeakPolarHBondContact O-CB 3.34Å; I94-I98 VanDerWaalsContact O-CG1 3.23Å; I94-I98 WeakPolarHBondContact O-CG1 3.37Å; I94-I98 PolarHBondContact O-N 3Å; G95-I98 PolarHBondContact O-N 3.32Å; I98-S100 PolarHBondContact O-N 3.01Å; I98-N101 PolarHBondContact O-N 2.64Å; I98-I102 HydrophobicContact CG2-CD1 3.43Å; I98-I102 VanDerWaalsContact CG2-CD1 3.43Å; I98-I102 HydrophobicContact CG2-CG1 4.27Å; I98-I102 VanDerWaalsContact O-CB 3.3Å; I98-I102 WeakPolarHBondContact O-CB 3.48Å; I98-I102 WeakPolarHBondContact O-CG1 3.42Å; I98-I102 PolarHBondContact O-N 3.27Å; I98-V355 HydrophobicContact CD1-CG1 4.34Å; I98-V355 HydrophobicContact CG1-CG1 4.08Å; I98-V355 HydrophobicContact CG1-CG2 4.27Å
99	V	64.4	Low	62.1	Low	94 Å²	94	98.5 Å²	98.5	57%	0.57	49%	0.491	S	S	*	.	H	α-helix	trans	-63	-41.4	177.5	172.3	0	0	0	0	111.4	G95 Y96 N101 I102 R103	G95-V99 WeakPolarHBondContact O-CB 3.2Å; G95-V99 VanDerWaalsContact O-CG2 3.26Å; G95-V99 WeakPolarHBondContact O-CG2 3.46Å; G95-V99 PolarHBondContact O-N 3.36Å; Y96-V99 PolarHBondContact O-N 2.93Å; V99-N101 VanDerWaalsContact C-N 3.31Å; V99-N101 PolarHBondContact O-N 3.29Å; V99-I102 CarbonylContact O-C 3.53Å; V99-I102 PolarHBondContact O-N 3.47Å; V99-R103 WeakPolarHBondContact O-CB 3.25Å; V99-R103 PolarHBondContact O-N 3.29Å
100	S	62.7	Low	59.5	Low	59 Å²	59	102 Å²	102	41%	0.413	51%	0.51	S	S	.	.	H	α-helix	trans	-63.4	-36	176.4	-175.7	0	0	0	0	112.4	Y96 F97 I98	Y96-S100 WeakPolarHBondContact O-CB 3.44Å; Y96-S100 PolarHBondContact O-N 3.31Å; F97-S100 PolarHBondContact O-N 3.46Å; I98-S100 PolarHBondContact O-N 3.01Å
101	N	55.5	Low	57	Low	77 Å²	77	110 Å²	110	41%	0.412	55%	0.552	S	S	.	*	H	α-helix	trans	-78.7	-30.6	176.4	-75.9	-36.8	0	0	0	112.3	F97 I98 V99	F97-N101 VanDerWaalsContact O-CB 3.25Å; F97-N101 WeakPolarHBondContact O-CB 3.47Å; F97-N101 VanDerWaalsContact O-CG 3.23Å; F97-N101 PolarHBondContact O-N 3Å; F97-N101 PolarHBondContact O-ND2 3.49Å; I98-N101 PolarHBondContact O-N 2.64Å; V99-N101 VanDerWaalsContact C-N 3.31Å; V99-N101 PolarHBondContact O-N 3.29Å
102	I	50.9	Low	54.5	Low	80 Å²	80	112.9 Å²	112.9	41%	0.41	57%	0.573	S	S	.	*	H	α-helix	trans	-78.3	-19.7	174.4	-68	172.8	0	0	0	111.4	I98 V99 L104 R105	I98-I102 HydrophobicContact CG2-CD1 3.43Å; I98-I102 VanDerWaalsContact CG2-CD1 3.43Å; I98-I102 HydrophobicContact CG2-CG1 4.27Å; I98-I102 VanDerWaalsContact O-CB 3.3Å; I98-I102 WeakPolarHBondContact O-CB 3.48Å; I98-I102 WeakPolarHBondContact O-CG1 3.42Å; I98-I102 PolarHBondContact O-N 3.27Å; V99-I102 CarbonylContact O-C 3.53Å; V99-I102 PolarHBondContact O-N 3.47Å; I102-L104 PolarHBondContact O-N 3Å; I102-R105 WeakPolarHBondContact CG2-O 3.31Å; I102-R105 CarbonylContact O-C 3.09Å; I102-R105 WeakPolarHBondContact O-CA 3.06Å; I102-R105 PolarHBondContact O-N 2.73Å
103	R	43.6	Very low	52.4	Low	229 Å²	229	111.7 Å²	111.7	86%	0.864	58%	0.579	S	S	*	*	T	Hydrogen-bonded Turn	trans	-66.1	-1.3	174.2	-135.4	174.9	-176.4	-176.5	0.1	113.9	V99	V99-R103 WeakPolarHBondContact O-CB 3.25Å; V99-R103 PolarHBondContact O-N 3.29Å
104	L	48	Very low	50.3	Low	156 Å²	156	118 Å²	118	82%	0.817	61%	0.608	S	S	*	*	T	Hydrogen-bonded Turn	trans	-93	0.2	164	-89.7	160.3	0	0	0	114.1	I102	I102-L104 PolarHBondContact O-N 3Å
105	R	37.1	Very low	48.2	Very low	209 Å²	209	125.5 Å²	125.5	79%	0.789	64%	0.642	S	S	*	*	S	Bend	trans	-162.3	101.2	173.6	-162.8	167.4	-161.4	-173.1	3.3	111.4	I102	I102-R105 WeakPolarHBondContact CG2-O 3.31Å; I102-R105 CarbonylContact O-C 3.09Å; I102-R105 WeakPolarHBondContact O-CA 3.06Å; I102-R105 PolarHBondContact O-N 2.73Å
106	D	34.4	Very low	46.7	Very low	136 Å²	136	127.9 Å²	127.9	73%	0.727	67%	0.667	S	S	*	*			trans	16	135.6	170.2	-52.9	-36.8	0	0	0	121.4
107	P	35.4	Very low	45.1	Very low	120 Å²	120	128.4 Å²	128.4	78%	0.779	68%	0.677	S	S	*	*	P	Polyproline II helix	trans	-81.6	127.4	-172.4	31.7	-30.5	0	0	0	113.5
108	F	28.8	Very low	44	Very low	199 Å²	199	134.2 Å²	134.2	87%	0.873	71%	0.708	S	S	*	*	P	Polyproline II helix	trans	-80.6	142.9	165.4	-87.4	-85.2	0	0	0	111.7
109	P	36.2	Very low	42.9	Very low	114 Å²	114	133.4 Å²	133.4	74%	0.74	71%	0.708	S	S	*	*	P	Polyproline II helix	trans	-101.4	116.1	-178	35.2	-25.8	0	0	0	111.4
110	I	33	Very low	42	Very low	157 Å²	157	134.9 Å²	134.9	81%	0.805	71%	0.712	S	S	*	*			trans	-148.9	115.3	154.9	-38	171	0	0	0	108.8
111	L	35.6	Very low	41	Very low	167 Å²	167	138.9 Å²	138.9	87%	0.874	72%	0.724	S	S	*	*				-176.6	130.5	121.9	-114.5	85.4	0	0	0	110.4
112	S	34.8	Very low	40.4	Very low	112 Å²	112	140.6 Å²	140.6	78%	0.783	73%	0.73	S	S	*	*			trans	-89.2	133.9	172.5	179.3	0	0	0	0	109.9
113	P	43.3	Very low	40	Very low	112 Å²	112	138.4 Å²	138.4	73%	0.727	72%	0.718	S	S	*	*			trans	-94.2	106.4	-176.6	34	-26.9	0	0	0	110
114	K	40.4	Very low	40.1	Very low	190 Å²	190	128.4 Å²	128.4	83%	0.826	68%	0.682	S	S	*	*			trans	-170.3	105.5	153.8	-103.1	156.7	-166	-168.2	0	109
115	H	37.3	Very low	39.8	Very low	179 Å²	179	122.9 Å²	122.9	83%	0.829	66%	0.656	S	S	*	*	S	Bend	trans	159.4	135.7	143.6	-80.7	98.8	0	0	0	108.2
116	G	42.5	Very low	40.3	Very low	81 Å²	81	121.3 Å²	121.3	84%	0.835	65%	0.65	S	S	*	*			trans	-68.9	137.8	-176.2	0	0	0	0	0	113.1
117	I	47.2	Very low	41	Very low	142 Å²	142	115.3 Å²	115.3	73%	0.728	62%	0.619	S	S	*	*			trans	-104.6	0.9	-161.4	-71.5	165.6	0	0	0	114.3
118	L	45.9	Very low	41.5	Very low	136 Å²	136	109.7 Å²	109.7	71%	0.712	58%	0.582	S	S	*	*			trans	-126.9	90.5	-163.1	-69.2	166.7	0	0	0	114.2	F88	F88-L118 HydrophobicContact CE1-CD2 4.17Å; F88-L118 HydrophobicContact CZ-CD2 3.66Å
119	S	43.4	Very low	42.5	Very low	52 Å²	52	101.7 Å²	101.7	36%	0.364	55%	0.55	S	S	.	.			trans	-128.1	131.8	147.6	175.2	0	0	0	0	108.6	E121 Q122 L123	S119-E121 PolarHBondContact O-N 3.37Å; S119-E121 VanDerWaalsContact O-N 3.14Å; S119-Q122 PolarHBondContact O-N 3.31Å; S119-Q122 VanDerWaalsContact O-N 3.11Å; S119-L123 PolarHBondContact O-N 3.47Å
120	I	45.9	Very low	43.3	Very low	125 Å²	125	100.4 Å²	100.4	64%	0.641	54%	0.536	S	S	*	.	H	α-helix	trans	-55.2	-31.4	-177.3	-73.4	166	0	0	0	111.6	L123 I124	I120-L123 WeakPolarHBondContact O-CB 3.41Å; I120-L123 PolarHBondContact O-N 3.14Å; I120-I124 HydrophobicContact CG2-CD1 3.84Å; I120-I124 WeakPolarHBondContact O-CG1 3.41Å; I120-I124 PolarHBondContact O-N 3.06Å; I120-I124 VanDerWaalsContact O-N 3.1Å
121	E	42.6	Very low	44.3	Very low	144 Å²	144	92.9 Å²	92.9	67%	0.673	50%	0.497	S	S	*	.	H	α-helix	trans	-70.7	-38.9	179.9	-62.2	175.9	171.5	0	0	112.9	S119 L123 S125	S119-E121 PolarHBondContact O-N 3.37Å; S119-E121 VanDerWaalsContact O-N 3.14Å; E121-L123 PolarHBondContact O-N 3.08Å; E121-S125 PolarHBondContact O-N 3.42Å
122	Q	41.7	Very low	45.3	Very low	113 Å²	113	85 Å²	85	53%	0.528	46%	0.456	S	S	.	.	H	α-helix	trans	-73.5	-18.8	176.6	-66.7	-177.7	-8.9	0	0	112.5	S119 S125 R126	S119-Q122 PolarHBondContact O-N 3.31Å; S119-Q122 VanDerWaalsContact O-N 3.11Å; Q122-S125 PolarHBondContact O-OG 3.47Å; Q122-R126 WeakPolarHBondContact O-CG 3.33Å; Q122-R126 PolarHBondContact O-N 2.83Å
123	L	43.3	Very low	46.6	Very low	33 Å²	33	81.2 Å²	81.2	17%	0.173	43%	0.428	C	S	.	.	H	α-helix	trans	-85.1	-41	-179.8	-167	66.5	0	0	0	111.8	V87 F88 S119 I120 E121 S125 R126 V127	V87-L123 HydrophobicContact CB-CD1 4.03Å; V87-L123 HydrophobicContact CB-CD2 3.99Å; V87-L123 HydrophobicContact CB-CG 4.12Å; V87-L123 HydrophobicContact CG1-CD1 3.17Å; V87-L123 HydrophobicContact CG1-CD2 3.64Å; V87-L123 HydrophobicContact CG1-CG 3.72Å; V87-L123 HydrophobicContact CG2-CD1 3.69Å; V87-L123 HydrophobicContact CG2-CD2 3.66Å; V87-L123 HydrophobicContact CG2-CG 3.44Å; V87-L123 VanDerWaalsContact CG2-CG 3.44Å; F88-L123 HydrophobicContact CE2-CD2 3.95Å; F88-L123 HydrophobicContact CZ-CD2 4.19Å; S119-L123 PolarHBondContact O-N 3.47Å; I120-L123 WeakPolarHBondContact O-CB 3.41Å; I120-L123 PolarHBondContact O-N 3.14Å; E121-L123 PolarHBondContact O-N 3.08Å; L123-S125 PolarHBondContact O-N 3.41Å; L123-R126 PolarHBondContact O-N 3.42Å; L123-V127 WeakPolarHBondContact O-CG2 3.49Å; L123-V127 PolarHBondContact O-N 2.85Å
124	I	45.9	Very low	47.4	Very low	19 Å²	19	77.9 Å²	77.9	10%	0.097	40%	0.404	C	S	.	.	H	α-helix	trans	-62	-35.3	170.5	-66.8	163.7	0	0	0	110.6	L83 I120 G128 L394	L83-I124 HydrophobicContact CD1-CD1 3.9Å; L83-I124 HydrophobicContact CD1-CG1 3.52Å; L83-I124 HydrophobicContact CD2-CG1 4.18Å; I120-I124 HydrophobicContact CG2-CD1 3.84Å; I120-I124 WeakPolarHBondContact O-CG1 3.41Å; I120-I124 PolarHBondContact O-N 3.06Å; I120-I124 VanDerWaalsContact O-N 3.1Å; I124-G128 WeakPolarHBondContact O-CA 3.31Å; I124-G128 PolarHBondContact O-N 3.38Å; I124-L394 HydrophobicContact CG2-CD1 3.84Å; I124-L394 HydrophobicContact CG2-CD2 4.02Å
125	S	41.5	Very low	48.4	Very low	40 Å²	40	70.3 Å²	70.3	28%	0.28	37%	0.372	S	S	.	.	H	α-helix	trans	-68.6	-39.4	178.3	72.6	0	0	0	0	114.2	E121 Q122 L123 V129 Y399	E121-S125 PolarHBondContact O-N 3.42Å; Q122-S125 PolarHBondContact O-OG 3.47Å; L123-S125 PolarHBondContact O-N 3.41Å; S125-V129 VanDerWaalsContact O-CB 3.27Å; S125-V129 WeakPolarHBondContact O-CB 3.46Å; S125-V129 WeakPolarHBondContact O-CG2 3.44Å; S125-V129 PolarHBondContact O-N 3.1Å; S125-Y399 WeakPolarHBondContact CA-OH 3.48Å; S125-Y399 WeakPolarHBondContact CB-OH 3.27Å
126	R	48.1	Very low	49.8	Very low	176 Å²	176	61.8 Å²	61.8	66%	0.664	33%	0.332	S	S	*	.	H	α-helix	trans	-72.1	-44.6	178.5	-68.7	178.1	-177.8	-157.4	1.5	112.7	Q122 L123 V129 I130	Q122-R126 WeakPolarHBondContact O-CG 3.33Å; Q122-R126 PolarHBondContact O-N 2.83Å; L123-R126 PolarHBondContact O-N 3.42Å; R126-V129 PolarHBondContact O-N 3.42Å; R126-I130 VanDerWaalsContact O-CG1 3.31Å; R126-I130 WeakPolarHBondContact O-CG1 3.36Å; R126-I130 PolarHBondContact O-N 3.32Å; R126-I130 VanDerWaalsContact O-N 3.13Å
127	V	48.5	Very low	51.1	Low	11 Å²	11	61.5 Å²	61.5	7%	0.067	31%	0.311	C	S	.	.	H	α-helix	trans	-67.9	-41.5	178.1	178.7	0	0	0	0	110.7	L86 V87 L123 G131 M366	L86-V127 HydrophobicContact CB-CG1 4.42Å; L86-V127 HydrophobicContact CD1-CG1 4.28Å; V87-V127 HydrophobicContact CG2-CG2 3.56Å; L123-V127 WeakPolarHBondContact O-CG2 3.49Å; L123-V127 PolarHBondContact O-N 2.85Å; V127-G131 PolarHBondContact O-N 3.03Å; V127-M366 HydrophobicContact CG1-CG 3.8Å
128	G	46.2	Very low	52.1	Low	1 Å²	1	57.6 Å²	57.6	1%	0.01	29%	0.292	C	S	.	.	H	α-helix	trans	-63.3	-43.5	174.8	0	0	0	0	0	112.7	I124 I130 G131 V132 S370	I124-G128 WeakPolarHBondContact O-CA 3.31Å; I124-G128 PolarHBondContact O-N 3.38Å; G128-I130 PolarHBondContact O-N 2.99Å; G128-G131 PolarHBondContact O-N 3.38Å; G128-V132 WeakPolarHBondContact O-CB 3.4Å; G128-V132 WeakPolarHBondContact O-CG2 3.29Å; G128-V132 PolarHBondContact O-N 3.49Å; G128-S370 PolarHBondContact O-OG 2.96Å
129	V	48.6	Very low	53.2	Low	31 Å²	31	52.8 Å²	52.8	19%	0.188	27%	0.27	C	S	.	.	H	α-helix	trans	-63.4	-44.4	177.8	166.6	0	0	0	0	111.5	S125 R126 T133 F398 Y399 W402	S125-V129 VanDerWaalsContact O-CB 3.27Å; S125-V129 WeakPolarHBondContact O-CB 3.46Å; S125-V129 WeakPolarHBondContact O-CG2 3.44Å; S125-V129 PolarHBondContact O-N 3.1Å; R126-V129 PolarHBondContact O-N 3.42Å; V129-T133 VanDerWaalsContact O-CB 3.29Å; V129-T133 WeakPolarHBondContact O-CB 3.49Å; V129-T133 PolarHBondContact O-N 3.05Å; V129-T133 PolarHBondContact O-OG1 2.97Å; V129-F398 HydrophobicContact CG2-CE1 3.73Å; V129-F398 HydrophobicContact CG2-CZ 4.37Å; V129-Y399 HydrophobicContact CG2-CE1 4.33Å; V129-W402 HydrophobicContact CG1-CZ2 4.09Å
130	I	53	Low	54.5	Low	87 Å²	87	50.3 Å²	50.3	45%	0.446	25%	0.252	S	S	.	.	H	α-helix	trans	-66	-44.3	178.7	-62.3	166.1	0	0	0	110.6	R126 G128 T133 L134 M366	R126-I130 VanDerWaalsContact O-CG1 3.31Å; R126-I130 WeakPolarHBondContact O-CG1 3.36Å; R126-I130 PolarHBondContact O-N 3.32Å; R126-I130 VanDerWaalsContact O-N 3.13Å; G128-I130 PolarHBondContact O-N 2.99Å; I130-T133 WeakPolarHBondContact O-CB 3.44Å; I130-T133 PolarHBondContact O-N 2.59Å; I130-L134 HydrophobicContact CG2-CD1 4.13Å; I130-L134 WeakPolarHBondContact O-CG 3.38Å; I130-L134 PolarHBondContact O-N 3.48Å; I130-M366 HydrophobicContact CB-CE 4.37Å; I130-M366 HydrophobicContact CB-SD 3.81Å; I130-M366 HydrophobicContact CG2-CE 3.44Å; I130-M366 VanDerWaalsContact CG2-CE 3.44Å; I130-M366 HydrophobicContact CG2-SD 3.52Å; I130-M366 VanDerWaalsContact CG2-SD 3.52Å
131	G	54.9	Low	55.8	Low	0 Å²	0	49 Å²	49	0%	0	24%	0.242	C	C	.	.	H	α-helix	trans	-65.6	-41.6	178.2	0	0	0	0	0	113.6	V127 G128 T133 L134 M135 S370	V127-G131 PolarHBondContact O-N 3.03Å; G128-G131 PolarHBondContact O-N 3.38Å; G131-T133 VanDerWaalsContact C-N 3.33Å; G131-L134 PolarHBondContact O-N 3.08Å; G131-M135 WeakPolarHBondContact O-CB 3.25Å; G131-M135 PolarHBondContact O-N 3.37Å; G131-S370 WeakPolarHBondContact CA-OG 3.4Å
132	V	57.2	Low	57.1	Low	0 Å²	0	43.1 Å²	43.1	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-64	-40.2	174	171.1	0	0	0	0	110.4	G128 M135 A136 S370 Y399 F403	G128-V132 WeakPolarHBondContact O-CB 3.4Å; G128-V132 WeakPolarHBondContact O-CG2 3.29Å; G128-V132 PolarHBondContact O-N 3.49Å; V132-M135 PolarHBondContact O-N 3.4Å; V132-A136 WeakPolarHBondContact O-CB 3.42Å; V132-A136 PolarHBondContact O-N 3.5Å; V132-S370 PolarHBondContact N-OG 3.24Å; V132-S370 VanDerWaalsContact N-OG 3.08Å; V132-Y399 HydrophobicContact CG2-CD1 4.36Å; V132-F403 HydrophobicContact CG1-CB 3.59Å; V132-F403 HydrophobicContact CG1-CD2 4.03Å; V132-F403 HydrophobicContact CG1-CG 4.32Å
133	T	60.7	Low	58.6	Low	33 Å²	33	38.1 Å²	38.1	20%	0.202	20%	0.198	C	C	.	.	H	α-helix	trans	-60.9	-47.6	175.9	-56.3	0	0	0	0	110.7	V129 I130 G131 A136 L137 W402 I406	V129-T133 VanDerWaalsContact O-CB 3.29Å; V129-T133 WeakPolarHBondContact O-CB 3.49Å; V129-T133 PolarHBondContact O-N 3.05Å; V129-T133 PolarHBondContact O-OG1 2.97Å; I130-T133 WeakPolarHBondContact O-CB 3.44Å; I130-T133 PolarHBondContact O-N 2.59Å; G131-T133 VanDerWaalsContact C-N 3.33Å; T133-A136 PolarHBondContact O-N 3.29Å; T133-L137 HydrophobicContact CG2-CD1 4.28Å; T133-L137 WeakPolarHBondContact O-CB 3.4Å; T133-L137 VanDerWaalsContact O-CG 3.25Å; T133-L137 WeakPolarHBondContact O-CG 3.3Å; T133-L137 PolarHBondContact O-N 3.43Å; T133-W402 PolarHBondContact OG1-NE1 2.95Å; T133-I406 HydrophobicContact CG2-CD1 4.35Å; T133-I406 HydrophobicContact CG2-CG1 4.31Å; T133-I406 HydrophobicContact CG2-CG2 3.95Å
134	L	60.6	Low	60.1	Low	42 Å²	42	37.5 Å²	37.5	22%	0.22	20%	0.196	C	C	.	.	H	α-helix	trans	-64.8	-43.6	178.3	-71.6	165.8	0	0	0	112.4	I130 G131 A136 L137 L138 I363 M366	I130-L134 HydrophobicContact CG2-CD1 4.13Å; I130-L134 WeakPolarHBondContact O-CG 3.38Å; I130-L134 PolarHBondContact O-N 3.48Å; G131-L134 PolarHBondContact O-N 3.08Å; L134-A136 VanDerWaalsContact C-N 3.32Å; L134-A136 PolarHBondContact O-N 3.43Å; L134-L137 PolarHBondContact O-N 2.97Å; L134-L138 WeakPolarHBondContact O-CB 3.26Å; L134-L138 WeakPolarHBondContact O-CG 3.36Å; L134-L138 PolarHBondContact O-N 3.5Å; L134-I363 HydrophobicContact CD1-CB 4.33Å; L134-I363 HydrophobicContact CD1-CG1 3.94Å; L134-I363 HydrophobicContact CD1-CG2 4.09Å; L134-M366 HydrophobicContact CD1-CE 3.68Å
135	M	62.7	Low	61.6	Low	31 Å²	31	38.8 Å²	38.8	15%	0.153	20%	0.203	C	C	.	.	H	α-helix	trans	-62.4	-41.5	176.8	-175.7	178.3	175.2	0	0	111.5	G131 V132 S139 Y367 L374 F403	G131-M135 WeakPolarHBondContact O-CB 3.25Å; G131-M135 PolarHBondContact O-N 3.37Å; V132-M135 PolarHBondContact O-N 3.4Å; M135-S139 WeakPolarHBondContact O-CB 3.43Å; M135-S139 PolarHBondContact O-N 3.23Å; M135-Y367 HydrophobicContact CB-CD2 3.73Å; M135-Y367 HydrophobicContact CB-CE2 3.69Å; M135-Y367 HydrophobicContact CG-CD2 4Å; M135-Y367 HydrophobicContact CG-CE2 3.47Å; M135-Y367 VanDerWaalsContact CG-CE2 3.47Å; M135-Y367 HydrophobicContact SD-CE2 4.32Å; M135-L374 HydrophobicContact CE-CD1 4.02Å; M135-L374 HydrophobicContact SD-CD1 3.66Å; M135-F403 HydrophobicContact CB-CE2 4.42Å; M135-F403 HydrophobicContact CG-CE2 3.98Å; M135-F403 HydrophobicContact SD-CE2 4.38Å
136	A	66.4	Low	63	Low	0 Å²	0	39.3 Å²	39.3	0%	0	21%	0.206	C	C	.	.	H	α-helix	trans	-67.3	-42	178.1	0	0	0	0	0	112.1	V132 T133 L134 S139 G140 F403 I406 F407	V132-A136 WeakPolarHBondContact O-CB 3.42Å; V132-A136 PolarHBondContact O-N 3.5Å; T133-A136 PolarHBondContact O-N 3.29Å; L134-A136 VanDerWaalsContact C-N 3.32Å; L134-A136 PolarHBondContact O-N 3.43Å; A136-S139 PolarHBondContact O-N 2.88Å; A136-G140 PolarHBondContact O-N 3.21Å; A136-F403 HydrophobicContact CB-CD2 3.68Å; A136-F403 HydrophobicContact CB-CE2 3.84Å; A136-F403 HydrophobicContact CB-CG 4.34Å; A136-F403 WeakPolarHBondContact CB-O 3.34Å; A136-I406 HydrophobicContact CB-CB 3.61Å; A136-I406 HydrophobicContact CB-CG2 3.55Å; A136-F407 HydrophobicContact CB-CB 4.21Å
137	L	68.9	Low	64.4	Low	75 Å²	75	31.3 Å²	31.3	39%	0.393	18%	0.177	S	C	.	.	H	α-helix	trans	-61.9	-51.4	174.2	-71.4	176	0	0	0	111.6	T133 L134 S139 G140 F141 I406 S410	T133-L137 HydrophobicContact CG2-CD1 4.28Å; T133-L137 WeakPolarHBondContact O-CB 3.4Å; T133-L137 VanDerWaalsContact O-CG 3.25Å; T133-L137 WeakPolarHBondContact O-CG 3.3Å; T133-L137 PolarHBondContact O-N 3.43Å; L134-L137 PolarHBondContact O-N 2.97Å; L137-S139 VanDerWaalsContact C-N 3.34Å; L137-S139 PolarHBondContact O-N 2.76Å; L137-G140 PolarHBondContact O-N 3.33Å; L137-F141 WeakPolarHBondContact O-CB 3.26Å; L137-F141 PolarHBondContact O-N 3.07Å; L137-I406 HydrophobicContact CD2-CG2 3.82Å; L137-I406 HydrophobicContact CG-CG2 3.81Å; L137-S410 WeakPolarHBondContact CA-OG 3.38Å; L137-S410 PolarHBondContact O-OG 3.08Å
138	L	68.2	Low	65.7	Low	60 Å²	60	33.7 Å²	33.7	31%	0.314	19%	0.185	S	C	.	.	H	α-helix	trans	-63.3	-40.7	179.3	-70	173.1	0	0	0	111.7	L134 G142 L336 T339	L134-L138 WeakPolarHBondContact O-CB 3.26Å; L134-L138 WeakPolarHBondContact O-CG 3.36Å; L134-L138 PolarHBondContact O-N 3.5Å; L138-G142 PolarHBondContact O-N 2.89Å; L138-L336 HydrophobicContact CD1-CD1 4.37Å; L138-T339 HydrophobicContact CD2-CG2 4.38Å
139	S	69.4	Low	67	Low	36 Å²	36	36 Å²	36	25%	0.252	20%	0.199	S	C	.	.	H	α-helix	trans	-68.3	-37.9	176.8	-176.7	0	0	0	0	111.9	M135 A136 L137 A143 K277 F407	M135-S139 WeakPolarHBondContact O-CB 3.43Å; M135-S139 PolarHBondContact O-N 3.23Å; A136-S139 PolarHBondContact O-N 2.88Å; L137-S139 VanDerWaalsContact C-N 3.34Å; L137-S139 PolarHBondContact O-N 2.76Å; S139-A143 WeakPolarHBondContact O-CB 3.35Å; S139-A143 PolarHBondContact O-N 3.18Å; S139-K277 PolarHBondContact OG-NZ 3.05Å; S139-K277 VanDerWaalsContact OG-NZ 3.08Å; S139-F407 WeakPolarHBondContact O-CE2 3.25Å; S139-F407 WeakPolarHBondContact OG-CE2 3.28Å
140	G	70.4	Confident	68.2	Low	0 Å²	0	39.9 Å²	39.9	0%	0	21%	0.211	C	C	.	.	H	α-helix	trans	-69.9	-45.5	179.1	0	0	0	0	0	111.8	A136 L137 A143	A136-G140 PolarHBondContact O-N 3.21Å; L137-G140 PolarHBondContact O-N 3.33Å; G140-A143 PolarHBondContact O-N 3.34Å
141	F	72.4	Confident	69.3	Low	97 Å²	97	36.4 Å²	36.4	43%	0.425	19%	0.193	S	C	.	.	H	α-helix	trans	-59.5	-46.8	170.7	176.5	-99.5	0	0	0	111.7	L137 A143 V144 N145	L137-F141 WeakPolarHBondContact O-CB 3.26Å; L137-F141 PolarHBondContact O-N 3.07Å; F141-A143 VanDerWaalsContact C-N 3.32Å; F141-A143 PolarHBondContact O-N 3.21Å; F141-V144 PolarHBondContact O-N 3.18Å; F141-N145 HydrophobicContact CD1-CB 4.22Å; F141-N145 HydrophobicContact CE1-CB 3.8Å; F141-N145 HydrophobicContact CE2-CB 4.24Å; F141-N145 HydrophobicContact CZ-CB 3.81Å; F141-N145 VanDerWaalsContact O-CB 3.3Å; F141-N145 WeakPolarHBondContact O-CB 3.29Å; F141-N145 PolarHBondContact O-N 3.35Å
142	G	71.2	Confident	70.4	Confident	20 Å²	20	38.5 Å²	38.5	21%	0.206	21%	0.207	C	C	.	.	H	α-helix	trans	-60.5	-38.8	177.9	0	0	0	0	0	113.1	L138 V144 N145 C146	L138-G142 PolarHBondContact O-N 2.89Å; G142-V144 PolarHBondContact O-N 2.94Å; G142-V144 VanDerWaalsContact O-N 3.16Å; G142-N145 PolarHBondContact O-N 3.45Å; G142-C146 WeakPolarHBondContact O-CB 3.4Å; G142-C146 PolarHBondContact O-N 2.88Å; G142-C146 PolarHBondContact O-SG 2.81Å
143	A	71.9	Confident	71.4	Confident	9 Å²	9	46.6 Å²	46.6	7%	0.074	24%	0.239	C	C	.	.	H	α-helix	trans	-60.6	-26.2	178.9	0	0	0	0	0	113.3	S139 G140 F141 P147 C274 F407	S139-A143 WeakPolarHBondContact O-CB 3.35Å; S139-A143 PolarHBondContact O-N 3.18Å; G140-A143 PolarHBondContact O-N 3.34Å; F141-A143 VanDerWaalsContact C-N 3.32Å; F141-A143 PolarHBondContact O-N 3.21Å; A143-P147 VanDerWaalsContact O-CD 3.25Å; A143-P147 WeakPolarHBondContact O-CD 3.37Å; A143-P147 WeakPolarHBondContact O-CG 3.44Å; A143-C274 VanDerWaalsContact CA-SG 3.55Å; A143-C274 HydrophobicContact CB-CB 4.07Å; A143-C274 WeakPolarHBondContact O-CB 3.12Å; A143-C274 PolarHBondContact O-SG 2.9Å; A143-C274 VanDerWaalsContact O-SG 3.35Å; A143-F407 HydrophobicContact CB-CE2 4.03Å; A143-F407 HydrophobicContact CB-CZ 3.99Å
144	V	76.6	Confident	72.3	Confident	19 Å²	19	48.8 Å²	48.8	12%	0.115	25%	0.246	C	C	.	.	H	α-helix	trans	-99.1	-45.1	179.9	-172.8	0	0	0	0	111.1	F141 G142 P147 Y148 A411 I415 L418	F141-V144 PolarHBondContact O-N 3.18Å; G142-V144 PolarHBondContact O-N 2.94Å; G142-V144 VanDerWaalsContact O-N 3.16Å; V144-P147 WeakPolarHBondContact O-CD 3.37Å; V144-Y148 WeakPolarHBondContact O-CB 3.44Å; V144-Y148 PolarHBondContact O-N 3.02Å; V144-A411 HydrophobicContact CG2-CB 4.15Å; V144-A411 WeakPolarHBondContact CG2-O 3.45Å; V144-I415 HydrophobicContact CB-CG1 4.36Å; V144-I415 HydrophobicContact CG1-CB 4.5Å; V144-I415 HydrophobicContact CG1-CG1 3.64Å; V144-I415 HydrophobicContact CG2-CD1 4.2Å; V144-I415 HydrophobicContact CG2-CG1 3.71Å; V144-L418 HydrophobicContact CG1-CD1 3.7Å
145	N	76.3	Confident	73	Confident	47 Å²	47	47.9 Å²	47.9	25%	0.251	24%	0.241	S	C	.	.	H	α-helix	trans	-72.2	-30.5	-175.8	-170.1	49.7	0	0	0	113	F141 G142 Y148 T149	F141-N145 HydrophobicContact CD1-CB 4.22Å; F141-N145 HydrophobicContact CE1-CB 3.8Å; F141-N145 HydrophobicContact CE2-CB 4.24Å; F141-N145 HydrophobicContact CZ-CB 3.81Å; F141-N145 VanDerWaalsContact O-CB 3.3Å; F141-N145 WeakPolarHBondContact O-CB 3.29Å; F141-N145 PolarHBondContact O-N 3.35Å; G142-N145 PolarHBondContact O-N 3.45Å; N145-Y148 PolarHBondContact O-N 3.31Å; N145-T149 VanDerWaalsContact O-CB 3.26Å; N145-T149 WeakPolarHBondContact O-CB 3.39Å; N145-T149 PolarHBondContact O-N 2.88Å; N145-T149 PolarHBondContact O-OG1 2.85Å; N145-T149 PolarHBondContact OD1-OG1 3Å
146	C	71.6	Confident	73.7	Confident	50 Å²	50	50.6 Å²	50.6	34%	0.338	25%	0.25	S	C	.	.	H	α-helix	trans	-64.7	-51.9	178.3	-73.5	0	0	0	0	112.3	G142 Y148 T149 Y150	G142-C146 WeakPolarHBondContact O-CB 3.4Å; G142-C146 PolarHBondContact O-N 2.88Å; G142-C146 PolarHBondContact O-SG 2.81Å; C146-Y148 VanDerWaalsContact C-N 3.32Å; C146-Y148 PolarHBondContact O-N 3.27Å; C146-T149 PolarHBondContact O-N 2.59Å; C146-Y150 HydrophobicContact CB-CD2 4.37Å; C146-Y150 HydrophobicContact CB-CE2 4.49Å; C146-Y150 VanDerWaalsContact O-CD2 3.25Å; C146-Y150 WeakPolarHBondContact O-CD2 3.49Å; C146-Y150 PolarHBondContact O-N 3.13Å
147	P	76.6	Confident	74.3	Confident	8 Å²	8	57.5 Å²	57.5	5%	0.052	29%	0.287	C	S	.	.	H	α-helix	trans	-56.7	-44.4	171.4	-26.2	34.3	0	0	0	112.6	A143 V144 T149 M151	A143-P147 VanDerWaalsContact O-CD 3.25Å; A143-P147 WeakPolarHBondContact O-CD 3.37Å; A143-P147 WeakPolarHBondContact O-CG 3.44Å; V144-P147 WeakPolarHBondContact O-CD 3.37Å; P147-T149 VanDerWaalsContact C-N 3.28Å; P147-T149 PolarHBondContact O-N 3.04Å; P147-M151 WeakPolarHBondContact O-CB 3.28Å; P147-M151 PolarHBondContact O-N 2.88Å
148	Y	75.6	Confident	74.9	Confident	62 Å²	62	54.9 Å²	54.9	24%	0.243	27%	0.274	C	S	.	.	H	α-helix	trans	-60.2	-36.3	179.2	-173.5	-103.2	0	0	0	113.2	V144 N145 C146 F154 L418	V144-Y148 WeakPolarHBondContact O-CB 3.44Å; V144-Y148 PolarHBondContact O-N 3.02Å; N145-Y148 PolarHBondContact O-N 3.31Å; C146-Y148 VanDerWaalsContact C-N 3.32Å; C146-Y148 PolarHBondContact O-N 3.27Å; Y148-F154 HydrophobicContact CD2-CB 3.91Å; Y148-F154 HydrophobicContact CD2-CD1 4.35Å; Y148-F154 HydrophobicContact CD2-CD2 4.35Å; Y148-F154 AromaticContact CD2-CG 3.98Å; Y148-F154 HydrophobicContact CD2-CG 3.98Å; Y148-F154 HydrophobicContact CE2-CB 4.16Å; Y148-L418 HydrophobicContact CD1-CD1 4.25Å; Y148-L418 HydrophobicContact CD1-CD2 4.03Å; Y148-L418 HydrophobicContact CD2-CD1 4.18Å; Y148-L418 HydrophobicContact CE1-CD2 3.93Å; Y148-L418 HydrophobicContact CG-CD1 3.9Å; Y148-L418 HydrophobicContact CG-CD2 4.4Å
149	T	74.6	Confident	75.8	Confident	50 Å²	50	55.2 Å²	55.2	31%	0.307	28%	0.278	S	S	.	.	H	α-helix	trans	-82.7	-38.1	-177	-59.3	0	0	0	0	113.1	N145 C146 P147	N145-T149 VanDerWaalsContact O-CB 3.26Å; N145-T149 WeakPolarHBondContact O-CB 3.39Å; N145-T149 PolarHBondContact O-N 2.88Å; N145-T149 PolarHBondContact O-OG1 2.85Å; N145-T149 PolarHBondContact OD1-OG1 3Å; C146-T149 PolarHBondContact O-N 2.59Å; P147-T149 VanDerWaalsContact C-N 3.28Å; P147-T149 PolarHBondContact O-N 3.04Å
150	Y	73.5	Confident	76.7	Confident	112 Å²	112	58 Å²	58	44%	0.439	29%	0.29	S	S	.	.	H	α-helix	trans	-94.4	-22.2	-172.7	-67.6	-55.7	0	0	0	114.2	C146 F263	C146-Y150 HydrophobicContact CB-CD2 4.37Å; C146-Y150 HydrophobicContact CB-CE2 4.49Å; C146-Y150 VanDerWaalsContact O-CD2 3.25Å; C146-Y150 WeakPolarHBondContact O-CD2 3.49Å; C146-Y150 PolarHBondContact O-N 3.13Å; Y150-F263 HydrophobicContact CD1-CB 4.33Å; Y150-F263 HydrophobicContact CD1-CD1 4.29Å; Y150-F263 HydrophobicContact CE1-CD1 4.16Å
151	M	76.6	Confident	77.6	Confident	14 Å²	14	62.6 Å²	62.6	7%	0.069	32%	0.319	C	S	.	.			trans	-85.1	123.5	-175	-161	168.3	89.7	0	0	111.4	P147 Y153 F154 L155 N264 Y268	P147-M151 WeakPolarHBondContact O-CB 3.28Å; P147-M151 PolarHBondContact O-N 2.88Å; M151-Y153 VanDerWaalsContact CE-CB 3.42Å; M151-Y153 HydrophobicContact CE-CD1 3.31Å; M151-Y153 HydrophobicContact CE-CE1 4.29Å; M151-Y153 HydrophobicContact CE-CG 3.61Å; M151-Y153 PolarHBondContact O-N 3.46Å; M151-Y153 VanDerWaalsContact O-N 3.16Å; M151-F154 HydrophobicContact CB-CD2 4.02Å; M151-F154 HydrophobicContact CE-CD2 3.42Å; M151-F154 VanDerWaalsContact CE-CD2 3.42Å; M151-F154 HydrophobicContact CE-CE1 4.3Å; M151-F154 HydrophobicContact CE-CE2 3.1Å; M151-F154 HydrophobicContact CE-CG 4.15Å; M151-F154 HydrophobicContact CE-CZ 3.59Å; M151-F154 PolarHBondContact O-N 3.09Å; M151-F154 HydrophobicContact SD-CD2 4.36Å; M151-F154 HydrophobicContact SD-CE2 4.12Å; M151-L155 VanDerWaalsContact O-CD1 3.29Å; M151-L155 WeakPolarHBondContact O-CD1 3.37Å; M151-N264 WeakPolarHBondContact CA-OD1 3.44Å; M151-Y268 HydrophobicContact CE-CE1 4.45Å; M151-Y268 HydrophobicContact CG-CD1 4.33Å; M151-Y268 HydrophobicContact CG-CE1 3.82Å; M151-Y268 HydrophobicContact CG-CE2 4.25Å; M151-Y268 HydrophobicContact SD-CD1 3.72Å; M151-Y268 HydrophobicContact SD-CE1 3.42Å; M151-Y268 WeakPolarHBondContact SD-CE1 3.29Å
152	S	76.1	Confident	78.3	Confident	43 Å²	43	60.9 Å²	60.9	30%	0.301	31%	0.314	S	S	.	.	G	3₁₀ helix	trans	-60.4	-25.3	177.3	66.1	0	0	0	0	113	F154 L155 N264	S152-F154 VanDerWaalsContact C-N 3.33Å; S152-F154 PolarHBondContact O-N 3.49Å; S152-L155 WeakPolarHBondContact O-CB 3.29Å; S152-L155 PolarHBondContact O-N 2.88Å; S152-N264 PolarHBondContact N-OD1 3.41Å; S152-N264 PolarHBondContact OG-ND2 3.41Å; S152-N264 PolarHBondContact OG-OD1 2.95Å
153	Y	79.6	Confident	79.3	Confident	170 Å²	170	60.1 Å²	60.1	67%	0.667	31%	0.305	S	S	*	.	G	3₁₀ helix	trans	-64.7	-32.1	179.2	175.7	-86.8	0	0	0	113.4	M151 L155	M151-Y153 VanDerWaalsContact CE-CB 3.42Å; M151-Y153 HydrophobicContact CE-CD1 3.31Å; M151-Y153 HydrophobicContact CE-CE1 4.29Å; M151-Y153 HydrophobicContact CE-CG 3.61Å; M151-Y153 PolarHBondContact O-N 3.46Å; M151-Y153 VanDerWaalsContact O-N 3.16Å; Y153-L155 VanDerWaalsContact C-N 3.31Å
154	F	78.9	Confident	80.3	Confident	79 Å²	79	63.6 Å²	63.6	35%	0.346	32%	0.322	S	S	.	.	G	3₁₀ helix	trans	-86.7	0.2	177.7	-67.5	-60.1	0	0	0	113.1	Y148 M151 S152 R156	Y148-F154 HydrophobicContact CD2-CB 3.91Å; Y148-F154 HydrophobicContact CD2-CD1 4.35Å; Y148-F154 HydrophobicContact CD2-CD2 4.35Å; Y148-F154 AromaticContact CD2-CG 3.98Å; Y148-F154 HydrophobicContact CD2-CG 3.98Å; Y148-F154 HydrophobicContact CE2-CB 4.16Å; M151-F154 HydrophobicContact CB-CD2 4.02Å; M151-F154 HydrophobicContact CE-CD2 3.42Å; M151-F154 VanDerWaalsContact CE-CD2 3.42Å; M151-F154 HydrophobicContact CE-CE1 4.3Å; M151-F154 HydrophobicContact CE-CE2 3.1Å; M151-F154 HydrophobicContact CE-CG 4.15Å; M151-F154 HydrophobicContact CE-CZ 3.59Å; M151-F154 PolarHBondContact O-N 3.09Å; M151-F154 HydrophobicContact SD-CD2 4.36Å; M151-F154 HydrophobicContact SD-CE2 4.12Å; S152-F154 VanDerWaalsContact C-N 3.33Å; S152-F154 PolarHBondContact O-N 3.49Å; F154-R156 PolarHBondContact O-N 3.4Å
155	L	75.9	Confident	81	Confident	23 Å²	23	65.2 Å²	65.2	12%	0.12	34%	0.337	C	S	.	.	S	Bend	trans	-74.9	127.5	173.4	-84.8	60.6	0	0	0	109.2	M151 S152 Y153 N157 R251 I252	M151-L155 VanDerWaalsContact O-CD1 3.29Å; M151-L155 WeakPolarHBondContact O-CD1 3.37Å; S152-L155 WeakPolarHBondContact O-CB 3.29Å; S152-L155 PolarHBondContact O-N 2.88Å; Y153-L155 VanDerWaalsContact C-N 3.31Å; L155-N157 PolarHBondContact O-N 3.43Å; L155-R251 HydrophobicContact CD2-CB 4.02Å; L155-I252 HydrophobicContact CD2-CG1 3.94Å
156	R	77.9	Confident	81.7	Confident	88 Å²	88	63.8 Å²	63.8	33%	0.332	33%	0.33	S	S	.	.	P	Polyproline II helix	trans	-58.3	132.1	166.8	178.8	175.7	174.3	176.7	0.3	108.7	F154 V158	F154-R156 PolarHBondContact O-N 3.4Å; R156-V158 HydrophobicContact CG-CG2 4.25Å; R156-V158 PolarHBondContact O-N 3.34Å
157	N	77.4	Confident	82.7	Confident	146 Å²	146	64 Å²	64	78%	0.781	33%	0.326	S	S	*	.	P	Polyproline II helix	trans	-71.9	117.6	171.4	-67.9	-51.8	0	0	0	108.6	L155	L155-N157 PolarHBondContact O-N 3.43Å
158	V	82.9	Confident	83.6	Confident	20 Å²	20	71.7 Å²	71.7	12%	0.121	35%	0.354	C	S	.	.			trans	-117.2	126.1	177.6	179.5	0	0	0	0	108.1	R156 I163 L245 T248 I252	R156-V158 HydrophobicContact CG-CG2 4.25Å; R156-V158 PolarHBondContact O-N 3.34Å; V158-I163 HydrophobicContact CG1-CD1 3.9Å; V158-I163 HydrophobicContact CG1-CG1 3.79Å; V158-L245 HydrophobicContact CG1-CB 4.27Å; V158-L245 HydrophobicContact CG1-CD2 3.96Å; V158-L245 HydrophobicContact CG2-CD2 3.71Å; V158-T248 HydrophobicContact CG2-CG2 3.62Å; V158-I252 HydrophobicContact CB-CD1 4.35Å
159	T	86.5	Confident	84.4	Confident	66 Å²	66	75.2 Å²	75.2	41%	0.405	37%	0.366	S	S	.	.			trans	-99	155.1	174.5	65.3	0	0	0	0	111	T161 D162 I163	T159-T161 PolarHBondContact O-N 2.95Å; T159-T161 PolarHBondContact OG1-OG1 3.44Å; T159-D162 PolarHBondContact N-OD2 2.96Å; T159-D162 WeakPolarHBondContact O-CB 3.34Å; T159-D162 PolarHBondContact O-N 2.94Å; T159-D162 PolarHBondContact OG1-N 2.87Å; T159-D162 PolarHBondContact OG1-OD1 2.9Å; T159-D162 PolarHBondContact OG1-OD2 3.44Å; T159-I163 PolarHBondContact O-N 3.41Å
160	D	89.1	Confident	85.3	Confident	94 Å²	94	73.6 Å²	73.6	50%	0.503	36%	0.356	S	S	.	.	H	α-helix	trans	-59.6	-29.9	175.4	-68	-43.8	0	0	0	112.1	L164 K249	D160-L164 WeakPolarHBondContact O-CB 3.31Å; D160-L164 VanDerWaalsContact O-CG 3.26Å; D160-L164 WeakPolarHBondContact O-CG 3.48Å; D160-L164 PolarHBondContact O-N 3.42Å; D160-K249 VanDerWaalsContact OD1-CE 3.25Å; D160-K249 WeakPolarHBondContact OD1-CE 3.39Å; D160-K249 IonicContact OD1-NZ 2.63Å; D160-K249 PolarHBondContact OD1-NZ 2.98Å
161	T	89.1	Confident	86.4	Confident	98 Å²	98	73.2 Å²	73.2	60%	0.601	36%	0.361	S	S	*	.	H	α-helix	trans	-66.2	-35.6	175.5	42.7	0	0	0	0	112.8	T159 A165	T159-T161 PolarHBondContact O-N 2.95Å; T159-T161 PolarHBondContact OG1-OG1 3.44Å; T161-A165 WeakPolarHBondContact O-CB 3.3Å; T161-A165 PolarHBondContact O-N 3.36Å
162	D	87.3	Confident	87.3	Confident	60 Å²	60	78.4 Å²	78.4	32%	0.321	39%	0.385	S	S	.	.	H	α-helix	trans	-68.4	-42.6	178.6	-58.2	-39	0	0	0	111	T159 A165 L166	T159-D162 PolarHBondContact N-OD2 2.96Å; T159-D162 WeakPolarHBondContact O-CB 3.34Å; T159-D162 PolarHBondContact O-N 2.94Å; T159-D162 PolarHBondContact OG1-N 2.87Å; T159-D162 PolarHBondContact OG1-OD1 2.9Å; T159-D162 PolarHBondContact OG1-OD2 3.44Å; D162-A165 PolarHBondContact O-N 3.42Å; D162-L166 PolarHBondContact O-N 2.92Å
163	I	90.5	Very high	88.1	Confident	4 Å²	4	76.6 Å²	76.6	2%	0.021	37%	0.372	C	S	.	.	H	α-helix	trans	-61.5	-50.2	176.7	-64.5	171.8	0	0	0	109.8	V158 T159 A165 L166 E167 L245 Y246 K249	V158-I163 HydrophobicContact CG1-CD1 3.9Å; V158-I163 HydrophobicContact CG1-CG1 3.79Å; T159-I163 PolarHBondContact O-N 3.41Å; I163-A165 VanDerWaalsContact C-N 3.3Å; I163-A165 PolarHBondContact O-N 2.92Å; I163-L166 PolarHBondContact O-N 3.5Å; I163-E167 HydrophobicContact CG2-CG 4.41Å; I163-E167 WeakPolarHBondContact O-CG 3.27Å; I163-E167 PolarHBondContact O-N 3.43Å; I163-L245 HydrophobicContact CG1-CB 4.02Å; I163-L245 HydrophobicContact CG1-CD1 4.4Å; I163-Y246 HydrophobicContact CG2-CD2 4.16Å; I163-Y246 HydrophobicContact CG2-CE1 4.05Å; I163-Y246 HydrophobicContact CG2-CE2 3.49Å; I163-Y246 VanDerWaalsContact CG2-CE2 3.49Å; I163-Y246 VanDerWaalsContact CG2-CZ 3.43Å; I163-K249 HydrophobicContact CD1-CB 4.11Å; I163-K249 HydrophobicContact CD1-CD 3.62Å; I163-K249 HydrophobicContact CD1-CG 4.44Å
164	L	93.1	Very high	88.8	Confident	83 Å²	83	72.2 Å²	72.2	44%	0.435	36%	0.359	S	S	.	.	H	α-helix	trans	-62.1	-36.7	179.2	-71.6	171.6	0	0	0	112.5	D160 R168	D160-L164 WeakPolarHBondContact O-CB 3.31Å; D160-L164 VanDerWaalsContact O-CG 3.26Å; D160-L164 WeakPolarHBondContact O-CG 3.48Å; D160-L164 PolarHBondContact O-N 3.42Å; L164-R168 WeakPolarHBondContact O-CB 3.46Å; L164-R168 VanDerWaalsContact O-CG 3.24Å; L164-R168 WeakPolarHBondContact O-CG 3.37Å; L164-R168 PolarHBondContact O-N 3.41Å
165	A	91.4	Very high	89.7	Confident	52 Å²	52	73.4 Å²	73.4	43%	0.43	37%	0.369	S	S	.	.	H	α-helix	trans	-65.5	-42.9	176.5	0	0	0	0	0	111.6	T161 D162 I163 R168 R169	T161-A165 WeakPolarHBondContact O-CB 3.3Å; T161-A165 PolarHBondContact O-N 3.36Å; D162-A165 PolarHBondContact O-N 3.42Å; I163-A165 VanDerWaalsContact C-N 3.3Å; I163-A165 PolarHBondContact O-N 2.92Å; A165-R168 PolarHBondContact O-N 3.2Å; A165-R169 PolarHBondContact O-N 3Å; A165-R169 VanDerWaalsContact O-N 3.12Å
166	L	90.8	Very high	90.5	Very high	17 Å²	17	76.5 Å²	76.5	9%	0.089	38%	0.383	C	S	.	.	H	α-helix	trans	-70.6	-39.6	179.1	-164.4	67.3	0	0	0	112.1	D162 I163 R168 R169 L170 L238 E241 T242 L245	D162-L166 PolarHBondContact O-N 2.92Å; I163-L166 PolarHBondContact O-N 3.5Å; L166-R168 VanDerWaalsContact C-N 3.34Å; L166-R168 PolarHBondContact O-N 3.41Å; L166-R169 WeakPolarHBondContact O-CB 3.45Å; L166-R169 PolarHBondContact O-N 3.43Å; L166-R169 VanDerWaalsContact O-N 3.16Å; L166-L170 PolarHBondContact O-N 3.5Å; L166-L238 HydrophobicContact CD1-CD2 3.69Å; L166-E241 HydrophobicContact CD2-CB 3.89Å; L166-E241 HydrophobicContact CD2-CG 3.62Å; L166-T242 WeakPolarHBondContact CD2-OG1 3.49Å; L166-L245 HydrophobicContact CB-CD1 4.43Å; L166-L245 HydrophobicContact CD2-CD1 3.65Å; L166-L245 HydrophobicContact CD2-CG 4.46Å
167	E	93.3	Very high	91.4	Very high	55 Å²	55	73 Å²	73	26%	0.257	37%	0.371	S	S	.	.	H	α-helix	trans	-58.6	-45.2	172.5	-78	-175.1	156.8	0	0	112	I163 R169 L170 L171 T242 Y246	I163-E167 HydrophobicContact CG2-CG 4.41Å; I163-E167 WeakPolarHBondContact O-CG 3.27Å; I163-E167 PolarHBondContact O-N 3.43Å; E167-R169 VanDerWaalsContact C-N 3.29Å; E167-R169 PolarHBondContact O-N 2.85Å; E167-L170 PolarHBondContact O-N 3.14Å; E167-L171 WeakPolarHBondContact O-CB 3.35Å; E167-L171 WeakPolarHBondContact O-CG 3.47Å; E167-L171 PolarHBondContact O-N 2.81Å; E167-T242 HydrophobicContact CG-CG2 3.88Å; E167-Y246 WeakPolarHBondContact OE1-CE2 3.25Å; E167-Y246 VanDerWaalsContact OE1-CZ 3.26Å; E167-Y246 PolarHBondContact OE1-OH 3.48Å
168	R	94.8	Very high	92.2	Very high	170 Å²	170	71.1 Å²	71.1	64%	0.642	36%	0.36	S	S	*	.	H	α-helix	trans	-59.7	-42.1	175.5	-75.2	173	-173.8	-179.7	3.4	111.4	L164 A165 L166 L171 Q172	L164-R168 WeakPolarHBondContact O-CB 3.46Å; L164-R168 VanDerWaalsContact O-CG 3.24Å; L164-R168 WeakPolarHBondContact O-CG 3.37Å; L164-R168 PolarHBondContact O-N 3.41Å; A165-R168 PolarHBondContact O-N 3.2Å; L166-R168 VanDerWaalsContact C-N 3.34Å; L166-R168 PolarHBondContact O-N 3.41Å; R168-L171 PolarHBondContact O-N 3.34Å; R168-Q172 WeakPolarHBondContact O-CB 3.15Å; R168-Q172 WeakPolarHBondContact O-CG 3.41Å; R168-Q172 PolarHBondContact O-N 3.1Å
169	R	92.9	Very high	92.8	Very high	135 Å²	135	72.6 Å²	72.6	51%	0.509	37%	0.372	S	S	.	.	H	α-helix	trans	-65.1	-39.7	177.4	-170.5	179.2	-178.7	-174.9	0.7	112.1	A165 L166 E167 T173 L238	A165-R169 PolarHBondContact O-N 3Å; A165-R169 VanDerWaalsContact O-N 3.12Å; L166-R169 WeakPolarHBondContact O-CB 3.45Å; L166-R169 PolarHBondContact O-N 3.43Å; L166-R169 VanDerWaalsContact O-N 3.16Å; E167-R169 VanDerWaalsContact C-N 3.29Å; E167-R169 PolarHBondContact O-N 2.85Å; R169-T173 WeakPolarHBondContact O-CB 3.41Å; R169-T173 PolarHBondContact O-N 3.06Å; R169-T173 PolarHBondContact O-OG1 3.35Å; R169-L238 HydrophobicContact CG-CD1 4.11Å; R169-L238 HydrophobicContact CG-CD2 4.34Å
170	L	94.6	Very high	93.1	Very high	16 Å²	16	71.8 Å²	71.8	8%	0.084	36%	0.362	C	S	.	.	H	α-helix	trans	-63.1	-49.5	174.9	176.8	63.2	0	0	0	111.1	L166 E167 Q172 T173 M174 S235 L238 F239	L166-L170 PolarHBondContact O-N 3.5Å; E167-L170 PolarHBondContact O-N 3.14Å; L170-Q172 PolarHBondContact O-N 3.16Å; L170-T173 WeakPolarHBondContact O-CB 3.34Å; L170-T173 PolarHBondContact O-N 3.08Å; L170-T173 VanDerWaalsContact O-N 3.11Å; L170-M174 HydrophobicContact CD1-CE 4.32Å; L170-M174 WeakPolarHBondContact O-CG 3.29Å; L170-M174 PolarHBondContact O-N 3.39Å; L170-S235 WeakPolarHBondContact CD1-O 3.26Å; L170-L238 HydrophobicContact CB-CB 4.36Å; L170-L238 HydrophobicContact CD1-CB 3.85Å; L170-F239 HydrophobicContact CD1-CB 4.3Å; L170-F239 HydrophobicContact CD2-CB 4.35Å; L170-F239 HydrophobicContact CD2-CD2 4.23Å
171	L	95.4	Very high	93.3	Very high	104 Å²	104	72.1 Å²	72.1	55%	0.545	36%	0.359	S	S	.	.	H	α-helix	trans	-60.5	-45.3	178.4	-71.2	171.6	0	0	0	111.8	E167 R168 T173 M174 D175	E167-L171 WeakPolarHBondContact O-CB 3.35Å; E167-L171 WeakPolarHBondContact O-CG 3.47Å; E167-L171 PolarHBondContact O-N 2.81Å; R168-L171 PolarHBondContact O-N 3.34Å; L171-T173 VanDerWaalsContact C-N 3.27Å; L171-T173 PolarHBondContact O-N 3.13Å; L171-M174 WeakPolarHBondContact O-CB 3.22Å; L171-M174 PolarHBondContact O-N 3.02Å; L171-D175 PolarHBondContact O-N 2.85Å
172	Q	95.7	Very high	93.4	Very high	123 Å²	123	74 Å²	74	58%	0.575	36%	0.359	S	S	*	.	H	α-helix	trans	-58.2	-40	173.9	-75.1	172.8	-6	0	0	112.1	R168 L170 D175 M176	R168-Q172 WeakPolarHBondContact O-CB 3.15Å; R168-Q172 WeakPolarHBondContact O-CG 3.41Å; R168-Q172 PolarHBondContact O-N 3.1Å; L170-Q172 PolarHBondContact O-N 3.16Å; Q172-D175 PolarHBondContact O-N 3.19Å; Q172-M176 WeakPolarHBondContact O-CG 3.46Å; Q172-M176 PolarHBondContact O-N 3.48Å
173	T	93.3	Very high	93.5	Very high	5 Å²	5	78.2 Å²	78.2	3%	0.031	37%	0.371	C	S	.	.	H	α-helix	trans	-66.6	-42.9	177.3	-55.3	0	0	0	0	111.3	R169 L170 L171 D175 M176 I177 L231 L234	R169-T173 WeakPolarHBondContact O-CB 3.41Å; R169-T173 PolarHBondContact O-N 3.06Å; R169-T173 PolarHBondContact O-OG1 3.35Å; L170-T173 WeakPolarHBondContact O-CB 3.34Å; L170-T173 PolarHBondContact O-N 3.08Å; L170-T173 VanDerWaalsContact O-N 3.11Å; L171-T173 VanDerWaalsContact C-N 3.27Å; L171-T173 PolarHBondContact O-N 3.13Å; T173-D175 VanDerWaalsContact C-N 3.35Å; T173-D175 PolarHBondContact O-N 2.88Å; T173-M176 HydrophobicContact CG2-CE 4.36Å; T173-M176 PolarHBondContact O-N 2.96Å; T173-I177 HydrophobicContact CG2-CD1 4.25Å; T173-I177 VanDerWaalsContact O-CG1 3.32Å; T173-I177 WeakPolarHBondContact O-CG1 3.35Å; T173-I177 PolarHBondContact O-N 3.36Å; T173-L231 HydrophobicContact CG2-CD2 4.26Å; T173-L234 HydrophobicContact CG2-CD2 4.21Å; T173-L234 HydrophobicContact CG2-CG 4.4Å
174	M	94.9	Very high	93.3	Very high	78 Å²	78	78.6 Å²	78.6	38%	0.384	37%	0.372	S	S	.	.	H	α-helix	trans	-59.8	-43.1	173.7	-72.9	-176.3	161.3	0	0	112	L170 L171 M176 I177 I178	L170-M174 HydrophobicContact CD1-CE 4.32Å; L170-M174 WeakPolarHBondContact O-CG 3.29Å; L170-M174 PolarHBondContact O-N 3.39Å; L171-M174 WeakPolarHBondContact O-CB 3.22Å; L171-M174 PolarHBondContact O-N 3.02Å; M174-M176 VanDerWaalsContact C-N 3.34Å; M174-M176 PolarHBondContact O-N 3.2Å; M174-I177 WeakPolarHBondContact O-CB 3.27Å; M174-I177 PolarHBondContact O-N 2.98Å; M174-I178 VanDerWaalsContact O-CG1 3.27Å; M174-I178 WeakPolarHBondContact O-CG1 3.44Å; M174-I178 PolarHBondContact O-N 3.49Å
175	D	96.7	Very high	93	Very high	104 Å²	104	77.5 Å²	77.5	56%	0.556	38%	0.375	S	S	*	.	H	α-helix	trans	-61.9	-40.4	176.6	-74.6	-27.2	0	0	0	112.2	L171 Q172 T173 I178 S179	L171-D175 PolarHBondContact O-N 2.85Å; Q172-D175 PolarHBondContact O-N 3.19Å; T173-D175 VanDerWaalsContact C-N 3.35Å; T173-D175 PolarHBondContact O-N 2.88Å; D175-I178 PolarHBondContact O-N 3.39Å; D175-S179 VanDerWaalsContact O-CB 3.29Å; D175-S179 WeakPolarHBondContact O-CB 3.46Å; D175-S179 PolarHBondContact O-N 2.78Å
176	M	93.6	Very high	92.8	Very high	88 Å²	88	79.9 Å²	79.9	43%	0.433	38%	0.379	S	S	.	.	H	α-helix	trans	-62.5	-43.1	174	-70	-170.7	-63.6	0	0	112	Q172 T173 M174 S179 K180 L231	Q172-M176 WeakPolarHBondContact O-CG 3.46Å; Q172-M176 PolarHBondContact O-N 3.48Å; T173-M176 HydrophobicContact CG2-CE 4.36Å; T173-M176 PolarHBondContact O-N 2.96Å; M174-M176 VanDerWaalsContact C-N 3.34Å; M174-M176 PolarHBondContact O-N 3.2Å; M176-S179 PolarHBondContact O-N 2.74Å; M176-K180 WeakPolarHBondContact O-CG 3.46Å; M176-K180 PolarHBondContact O-N 2.91Å; M176-L231 HydrophobicContact CB-CD1 4.33Å; M176-L231 HydrophobicContact CE-CD2 3.96Å
177	I	95.3	Very high	92.5	Very high	15 Å²	15	80.9 Å²	80.9	8%	0.077	39%	0.389	C	S	.	.	H	α-helix	trans	-61.5	-49.5	176.8	-66.8	164.2	0	0	0	110.1	T173 M174 S179 K180 K181 L231 E232	T173-I177 HydrophobicContact CG2-CD1 4.25Å; T173-I177 VanDerWaalsContact O-CG1 3.32Å; T173-I177 WeakPolarHBondContact O-CG1 3.35Å; T173-I177 PolarHBondContact O-N 3.36Å; M174-I177 WeakPolarHBondContact O-CB 3.27Å; M174-I177 PolarHBondContact O-N 2.98Å; I177-S179 VanDerWaalsContact C-N 3.31Å; I177-S179 PolarHBondContact O-N 2.97Å; I177-K180 PolarHBondContact O-N 3.48Å; I177-K181 HydrophobicContact CG2-CD 4.06Å; I177-K181 HydrophobicContact CG2-CG 4.3Å; I177-K181 WeakPolarHBondContact O-CB 3.45Å; I177-K181 WeakPolarHBondContact O-CG 3.36Å; I177-K181 PolarHBondContact O-N 2.88Å; I177-L231 HydrophobicContact CD1-CB 4.14Å; I177-L231 HydrophobicContact CG1-CB 3.61Å; I177-L231 HydrophobicContact CG1-CD1 4.43Å; I177-E232 HydrophobicContact CD1-CG 4.26Å; I177-E232 HydrophobicContact CG2-CG 4.34Å
178	I	95.9	Very high	91.9	Very high	106 Å²	106	84.9 Å²	84.9	54%	0.544	40%	0.402	S	S	.	.	H	α-helix	trans	-58.8	-46.1	179.3	-68	165	0	0	0	110.1	M174 D175 K181 K182	M174-I178 VanDerWaalsContact O-CG1 3.27Å; M174-I178 WeakPolarHBondContact O-CG1 3.44Å; M174-I178 PolarHBondContact O-N 3.49Å; D175-I178 PolarHBondContact O-N 3.39Å; I178-K181 PolarHBondContact O-N 3.25Å; I178-K182 VanDerWaalsContact O-CB 3.29Å; I178-K182 WeakPolarHBondContact O-CB 3.27Å; I178-K182 PolarHBondContact O-N 2.92Å
179	S	94.1	Very high	91.3	Very high	52 Å²	52	85 Å²	85	36%	0.364	40%	0.403	S	S	.	.	H	α-helix	trans	-60.5	-45.8	178.2	-173.8	0	0	0	0	112.2	D175 M176 I177 K182 R183	D175-S179 VanDerWaalsContact O-CB 3.29Å; D175-S179 WeakPolarHBondContact O-CB 3.46Å; D175-S179 PolarHBondContact O-N 2.78Å; M176-S179 PolarHBondContact O-N 2.74Å; I177-S179 VanDerWaalsContact C-N 3.31Å; I177-S179 PolarHBondContact O-N 2.97Å; S179-K182 PolarHBondContact O-N 3.48Å; S179-R183 WeakPolarHBondContact O-CG 3.44Å; S179-R183 PolarHBondContact O-N 3.37Å
180	K	92.9	Very high	90.7	Very high	49 Å²	49	81.8 Å²	81.8	21%	0.213	40%	0.398	C	S	.	.	H	α-helix	trans	-68	-43.4	177.9	-74.7	-177.7	-175.4	-83.8	0	112.4	M176 I177 K182 R183 M184 I224 E227 V228 L231	M176-K180 WeakPolarHBondContact O-CG 3.46Å; M176-K180 PolarHBondContact O-N 2.91Å; I177-K180 PolarHBondContact O-N 3.48Å; K180-K182 VanDerWaalsContact C-N 3.31Å; K180-K182 PolarHBondContact O-N 2.84Å; K180-R183 WeakPolarHBondContact O-CB 3.33Å; K180-R183 PolarHBondContact O-N 3.49Å; K180-R183 VanDerWaalsContact O-N 3.14Å; K180-M184 WeakPolarHBondContact O-CG 3.32Å; K180-M184 PolarHBondContact O-N 2.89Å; K180-I224 HydrophobicContact CB-CG2 4.38Å; K180-E227 HydrophobicContact CD-CB 4.43Å; K180-E227 IonicContact NZ-OE1 3.77Å; K180-E227 IonicContact NZ-OE2 3.96Å; K180-E227 PolarHBondContact NZ-OE2 3.31Å; K180-V228 HydrophobicContact CB-CG2 3.65Å; K180-V228 HydrophobicContact CD-CG2 4.33Å; K180-L231 HydrophobicContact CD-CD1 3.71Å
181	K	93	Very high	89.7	Confident	100 Å²	100	85.1 Å²	85.1	44%	0.435	41%	0.414	S	S	.	.	H	α-helix	trans	-60.2	-40.2	173.7	-75.4	-171.2	175.2	-174.5	0	112.2	I177 I178 M184 A185 V228 E232	I177-K181 HydrophobicContact CG2-CD 4.06Å; I177-K181 HydrophobicContact CG2-CG 4.3Å; I177-K181 WeakPolarHBondContact O-CB 3.45Å; I177-K181 WeakPolarHBondContact O-CG 3.36Å; I177-K181 PolarHBondContact O-N 2.88Å; I178-K181 PolarHBondContact O-N 3.25Å; K181-M184 WeakPolarHBondContact O-CB 3.17Å; K181-M184 PolarHBondContact O-N 3.07Å; K181-A185 WeakPolarHBondContact O-CB 3.44Å; K181-A185 PolarHBondContact O-N 3.03Å; K181-V228 HydrophobicContact CG-CG1 4.08Å; K181-V228 HydrophobicContact CG-CG2 4.45Å; K181-E232 WeakPolarHBondContact CE-OE1 3.39Å; K181-E232 IonicContact NZ-OE1 2.74Å; K181-E232 PolarHBondContact NZ-OE1 2.86Å
182	K	93	Very high	88.7	Confident	137 Å²	137	87.9 Å²	87.9	60%	0.596	42%	0.422	S	S	*	.	H	α-helix	trans	-62.3	-44.4	173.9	-172.2	-178.7	178.7	178.3	0	111.4	I178 S179 K180 M184 A185 M186	I178-K182 VanDerWaalsContact O-CB 3.29Å; I178-K182 WeakPolarHBondContact O-CB 3.27Å; I178-K182 PolarHBondContact O-N 2.92Å; S179-K182 PolarHBondContact O-N 3.48Å; K180-K182 VanDerWaalsContact C-N 3.31Å; K180-K182 PolarHBondContact O-N 2.84Å; K182-M184 PolarHBondContact O-N 3.28Å; K182-A185 PolarHBondContact O-N 2.82Å; K182-M186 HydrophobicContact CG-CE 4.17Å; K182-M186 WeakPolarHBondContact O-CG 3.21Å; K182-M186 PolarHBondContact O-N 2.7Å
183	R	87.8	Confident	87.5	Confident	150 Å²	150	86.9 Å²	86.9	57%	0.566	42%	0.417	S	S	*	.	H	α-helix	trans	-60.6	-42.5	175	-71.7	176.6	-168.8	-171	1.8	111.9	S179 K180 M186 A187	S179-R183 WeakPolarHBondContact O-CG 3.44Å; S179-R183 PolarHBondContact O-N 3.37Å; K180-R183 WeakPolarHBondContact O-CB 3.33Å; K180-R183 PolarHBondContact O-N 3.49Å; K180-R183 VanDerWaalsContact O-N 3.14Å; R183-M186 HydrophobicContact CG-CE 4.39Å; R183-M186 PolarHBondContact O-N 3.25Å; R183-A187 WeakPolarHBondContact O-CB 3.33Å; R183-A187 PolarHBondContact O-N 2.88Å
184	M	86.7	Confident	86.2	Confident	12 Å²	12	93.8 Å²	93.8	6%	0.059	45%	0.447	C	S	.	.	H	α-helix	trans	-61.9	-45.5	175.4	-71.3	177.7	67	0	0	112.7	K180 K181 K182 M186 A187 R188 L221 I224 Q225 V228	K180-M184 WeakPolarHBondContact O-CG 3.32Å; K180-M184 PolarHBondContact O-N 2.89Å; K181-M184 WeakPolarHBondContact O-CB 3.17Å; K181-M184 PolarHBondContact O-N 3.07Å; K182-M184 PolarHBondContact O-N 3.28Å; M184-M186 VanDerWaalsContact C-N 3.34Å; M184-M186 PolarHBondContact O-N 3.22Å; M184-A187 PolarHBondContact O-N 3.49Å; M184-R188 WeakPolarHBondContact O-CG 3.45Å; M184-R188 PolarHBondContact O-N 3.38Å; M184-L221 HydrophobicContact CE-CD2 4.11Å; M184-I224 HydrophobicContact CG-CB 4.22Å; M184-I224 HydrophobicContact CG-CG2 3.43Å; M184-I224 VanDerWaalsContact CG-CG2 3.43Å; M184-I224 HydrophobicContact SD-CG2 3.8Å; M184-Q225 HydrophobicContact CE-CB 4.1Å; M184-V228 HydrophobicContact SD-CG2 3.96Å
185	A	87	Confident	84.5	Confident	60 Å²	60	92.3 Å²	92.3	50%	0.496	45%	0.451	S	S	.	.	H	α-helix	trans	-62.8	-41.6	177.8	0	0	0	0	0	111.5	K181 K182 R189	K181-A185 WeakPolarHBondContact O-CB 3.44Å; K181-A185 PolarHBondContact O-N 3.03Å; K182-A185 PolarHBondContact O-N 2.82Å; A185-R189 WeakPolarHBondContact O-CB 3.5Å; A185-R189 PolarHBondContact O-N 3.5Å
186	M	87.8	Confident	82.4	Confident	102 Å²	102	94.6 Å²	94.6	50%	0.502	46%	0.459	S	S	.	.	H	α-helix	trans	-62.6	-47.7	173.7	-70.7	-171	-62.8	0	0	111.4	K182 R183 M184 R188 R189 T190	K182-M186 HydrophobicContact CG-CE 4.17Å; K182-M186 WeakPolarHBondContact O-CG 3.21Å; K182-M186 PolarHBondContact O-N 2.7Å; R183-M186 HydrophobicContact CG-CE 4.39Å; R183-M186 PolarHBondContact O-N 3.25Å; M184-M186 VanDerWaalsContact C-N 3.34Å; M184-M186 PolarHBondContact O-N 3.22Å; M186-R188 PolarHBondContact O-N 3.1Å; M186-R189 WeakPolarHBondContact O-CB 3.14Å; M186-R189 PolarHBondContact O-N 2.92Å; M186-R189 VanDerWaalsContact O-N 3.14Å; M186-T190 PolarHBondContact O-N 3.42Å; M186-T190 PolarHBondContact O-OG1 2.93Å
187	A	83.1	Confident	80.3	Confident	37 Å²	37	96.3 Å²	96.3	31%	0.306	47%	0.474	S	S	.	.	H	α-helix	trans	-60.5	-44.2	178.4	0	0	0	0	0	112.5	R183 M184 R189 T190 M191 L221	R183-A187 WeakPolarHBondContact O-CB 3.33Å; R183-A187 PolarHBondContact O-N 2.88Å; M184-A187 PolarHBondContact O-N 3.49Å; A187-R189 VanDerWaalsContact C-N 3.35Å; A187-R189 PolarHBondContact O-N 3.1Å; A187-T190 PolarHBondContact O-N 3.03Å; A187-M191 WeakPolarHBondContact O-CG 3.11Å; A187-M191 PolarHBondContact O-N 2.72Å; A187-L221 HydrophobicContact CB-CD1 4.18Å
188	R	81.8	Confident	78.2	Confident	139 Å²	139	101.1 Å²	101.1	53%	0.525	50%	0.496	S	S	.	.	H	α-helix	trans	-59.2	-45	172.9	-76.3	-170.5	-179.5	-165.2	2.7	111.3	M184 M186 T190 M191 F192 L221	M184-R188 WeakPolarHBondContact O-CG 3.45Å; M184-R188 PolarHBondContact O-N 3.38Å; M186-R188 PolarHBondContact O-N 3.1Å; R188-T190 PolarHBondContact O-N 3.28Å; R188-M191 WeakPolarHBondContact O-CB 3.15Å; R188-M191 PolarHBondContact O-N 2.89Å; R188-F192 WeakPolarHBondContact O-CD2 3.47Å; R188-F192 PolarHBondContact O-N 3.03Å; R188-L221 HydrophobicContact CG-CD1 3.9Å; R188-L221 HydrophobicContact CG-CD2 4.41Å
189	R	82.2	Confident	75.9	Confident	174 Å²	174	103.1 Å²	103.1	66%	0.657	51%	0.508	S	S	*	.	H	α-helix	trans	-61.5	-41.9	178	-172.2	176.5	-178.8	174.4	1.6	112.1	A185 M186 A187 M191 F192 Q193	A185-R189 WeakPolarHBondContact O-CB 3.5Å; A185-R189 PolarHBondContact O-N 3.5Å; M186-R189 WeakPolarHBondContact O-CB 3.14Å; M186-R189 PolarHBondContact O-N 2.92Å; M186-R189 VanDerWaalsContact O-N 3.14Å; A187-R189 VanDerWaalsContact C-N 3.35Å; A187-R189 PolarHBondContact O-N 3.1Å; R189-M191 VanDerWaalsContact C-N 3.34Å; R189-F192 PolarHBondContact O-N 3.39Å; R189-Q193 WeakPolarHBondContact O-CG 3Å; R189-Q193 PolarHBondContact O-N 3.36Å
190	T	80.7	Confident	73.7	Confident	67 Å²	67	109.4 Å²	109.4	41%	0.411	53%	0.528	S	S	.	.	H	α-helix	trans	-66.7	-36	176.7	-36.2	0	0	0	0	111.9	M186 A187 R188 K194	M186-T190 PolarHBondContact O-N 3.42Å; M186-T190 PolarHBondContact O-OG1 2.93Å; A187-T190 PolarHBondContact O-N 3.03Å; R188-T190 PolarHBondContact O-N 3.28Å; T190-K194 WeakPolarHBondContact O-CB 3.43Å; T190-K194 WeakPolarHBondContact O-CG 3.47Å; T190-K194 PolarHBondContact O-N 2.93Å
191	M	73.6	Confident	71.5	Confident	85 Å²	85	113 Å²	113	42%	0.419	56%	0.557	S	S	.	*	H	α-helix	trans	-64.2	-44.4	172.5	-72.1	-178.8	-179.5	0	0	111.9	A187 R188 R189 K194 G195 G217 L221	A187-M191 WeakPolarHBondContact O-CG 3.11Å; A187-M191 PolarHBondContact O-N 2.72Å; R188-M191 WeakPolarHBondContact O-CB 3.15Å; R188-M191 PolarHBondContact O-N 2.89Å; R189-M191 VanDerWaalsContact C-N 3.34Å; M191-K194 PolarHBondContact O-N 3.21Å; M191-G195 PolarHBondContact O-N 2.91Å; M191-G217 VanDerWaalsContact CE-C 3.44Å; M191-G217 VanDerWaalsContact CE-O 3.3Å; M191-G217 WeakPolarHBondContact CE-O 3.13Å; M191-L221 HydrophobicContact CE-CD1 4.02Å; M191-L221 HydrophobicContact SD-CD1 4.16Å
192	F	73.5	Confident	69.3	Low	162 Å²	162	113.8 Å²	113.8	71%	0.711	58%	0.575	S	S	*	*	H	α-helix	trans	-60.5	-46.1	175	-93	-79.5	0	0	0	112.1	R188 R189 K194 G195 E196	R188-F192 WeakPolarHBondContact O-CD2 3.47Å; R188-F192 PolarHBondContact O-N 3.03Å; R189-F192 PolarHBondContact O-N 3.39Å; F192-K194 PolarHBondContact O-N 2.74Å; F192-G195 PolarHBondContact O-N 3.35Å; F192-G195 VanDerWaalsContact O-N 3.13Å; F192-E196 PolarHBondContact O-N 3.32Å
193	Q	70.8	Confident	67.5	Low	102 Å²	102	110 Å²	110	48%	0.477	58%	0.575	S	S	.	*	H	α-helix	trans	-63.4	-38.3	176.7	-76.1	-178.7	-25.9	0	0	112.7	R189 G195 E196 V197	R189-Q193 WeakPolarHBondContact O-CG 3Å; R189-Q193 PolarHBondContact O-N 3.36Å; Q193-G195 VanDerWaalsContact C-N 3.33Å; Q193-E196 PolarHBondContact O-N 2.88Å; Q193-V197 WeakPolarHBondContact O-CG2 3.49Å; Q193-V197 PolarHBondContact O-N 2.89Å
194	K	65.1	Low	66.2	Low	150 Å²	150	110.7 Å²	110.7	65%	0.652	58%	0.582	S	S	*	*	H	α-helix	trans	-67.7	-33.4	172.9	-77.6	-178.8	177.3	-178.5	0	112.5	T190 M191 F192 H198	T190-K194 WeakPolarHBondContact O-CB 3.43Å; T190-K194 WeakPolarHBondContact O-CG 3.47Å; T190-K194 PolarHBondContact O-N 2.93Å; M191-K194 PolarHBondContact O-N 3.21Å; F192-K194 PolarHBondContact O-N 2.74Å; K194-H198 PolarHBondContact O-N 2.76Å
195	G	60	Low	64.8	Low	47 Å²	47	120.2 Å²	120.2	49%	0.485	62%	0.618	S	S	.	*	H	α-helix	trans	-65.4	-37.7	174.6	0	0	0	0	0	113.3	M191 F192 Q193	M191-G195 PolarHBondContact O-N 2.91Å; F192-G195 PolarHBondContact O-N 3.35Å; F192-G195 VanDerWaalsContact O-N 3.13Å; Q193-G195 VanDerWaalsContact C-N 3.33Å
196	E	52.3	Low	63.6	Low	153 Å²	153	118.5 Å²	118.5	72%	0.715	61%	0.606	S	S	*	*	H	α-helix	trans	-70.8	-36.1	175.7	-77	-174.4	141.2	0	0	113.1	F192 Q193 H198	F192-E196 PolarHBondContact O-N 3.32Å; Q193-E196 PolarHBondContact O-N 2.88Å; E196-H198 VanDerWaalsContact C-N 3.29Å; E196-H198 PolarHBondContact O-N 3.37Å
197	V	50.3	Low	62.2	Low	124 Å²	124	119.8 Å²	119.8	75%	0.752	61%	0.612	S	S	*	*	H	α-helix	trans	-71.3	-23.5	179.4	176.5	0	0	0	0	112.3	Q193 N199	Q193-V197 WeakPolarHBondContact O-CG2 3.49Å; Q193-V197 PolarHBondContact O-N 2.89Å; V197-N199 VanDerWaalsContact C-N 3.35Å; V197-N199 PolarHBondContact O-N 2.98Å
198	H	50	Low	61.1	Low	116 Å²	116	122.8 Å²	122.8	54%	0.537	62%	0.622	S	S	.	*	T	Hydrogen-bonded Turn	trans	-86.9	4.1	-176.5	-134.3	-34.3	0	0	0	115.2	K194 E196 K200	K194-H198 PolarHBondContact O-N 2.76Å; E196-H198 VanDerWaalsContact C-N 3.29Å; E196-H198 PolarHBondContact O-N 3.37Å; H198-K200 PolarHBondContact O-N 3.34Å
199	N	47.8	Very low	60	Low	147 Å²	147	122.6 Å²	122.6	79%	0.786	63%	0.625	S	S	*	*	T	Hydrogen-bonded Turn	trans	-76.6	9.7	177.8	-114.1	-5.6	0	0	0	114.7	V197	V197-N199 VanDerWaalsContact C-N 3.35Å; V197-N199 PolarHBondContact O-N 2.98Å
200	K	47.3	Very low	58.9	Low	184 Å²	184	116.1 Å²	116.1	80%	0.8	61%	0.606	S	S	*	*	S	Bend	trans	-118.2	108.9	164.6	-80.4	-174.5	176.1	178.7	0	109.5	H198	H198-K200 PolarHBondContact O-N 3.34Å
201	P	48.1	Very low	57.7	Low	124 Å²	124	117.8 Å²	117.8	81%	0.805	62%	0.616	S	S	*	*			trans	-79.6	132.5	-177.7	32	-30.6	0	0	0	109.9
202	S	45.5	Very low	56.8	Low	117 Å²	117	118.6 Å²	118.6	82%	0.818	63%	0.626	S	S	*	*			trans	-137.3	96	165.6	172.5	0	0	0	0	108.4
203	G	57	Low	56	Low	57 Å²	57	115.3 Å²	115.3	59%	0.588	62%	0.619	S	S	*	*			trans	94.1	141.1	161	0	0	0	0	0	117.7	W205 G206	G203-W205 PolarHBondContact O-N 3.42Å; G203-W205 VanDerWaalsContact O-N 3.1Å; G203-G206 PolarHBondContact O-N 2.86Å
204	F	59.2	Low	55.2	Low	165 Å²	165	114.1 Å²	114.1	72%	0.724	62%	0.622	S	S	*	*	H	α-helix	trans	-51.2	-28.7	173.9	-167.1	-100.8	0	0	0	113.5	G206 M207 I208	F204-G206 VanDerWaalsContact C-N 3.35Å; F204-G206 PolarHBondContact O-N 3.41Å; F204-M207 PolarHBondContact O-N 3.25Å; F204-I208 HydrophobicContact CD1-CD1 4.21Å; F204-I208 HydrophobicContact CE1-CD1 4.01Å
205	W	58.4	Low	54.6	Low	213 Å²	213	109.3 Å²	109.3	81%	0.807	61%	0.61	S	S	*	*	H	α-helix	trans	-68.4	-27	174.2	-117.5	92.1	0	0	0	114	G203	G203-W205 PolarHBondContact O-N 3.42Å; G203-W205 VanDerWaalsContact O-N 3.1Å
206	G	60.8	Low	54.5	Low	24 Å²	24	110.2 Å²	110.2	25%	0.247	61%	0.609	C	S	.	*	H	α-helix	trans	-73.8	-28.9	175.9	0	0	0	0	0	113.3	G203 F204 S210	G203-G206 PolarHBondContact O-N 2.86Å; F204-G206 VanDerWaalsContact C-N 3.35Å; F204-G206 PolarHBondContact O-N 3.41Å; G206-S210 PolarHBondContact O-N 3.34Å; G206-S210 VanDerWaalsContact O-N 3.14Å; G206-S210 PolarHBondContact O-OG 3.43Å
207	M	58.8	Low	54.9	Low	128 Å²	128	104.1 Å²	104.1	63%	0.631	59%	0.587	S	S	*	*	H	α-helix	trans	-75.2	-32	-178.4	-157.7	164.7	91.4	0	0	112.6	F204 S210 V211	F204-M207 PolarHBondContact O-N 3.25Å; M207-S210 PolarHBondContact O-OG 3.38Å; M207-S210 VanDerWaalsContact O-OG 3.06Å; M207-V211 WeakPolarHBondContact O-CG2 3.33Å
208	I	60.3	Low	55.5	Low	101 Å²	101	101.2 Å²	101.2	52%	0.518	57%	0.573	S	S	.	*	H	α-helix	trans	-80.6	-31.3	178.8	-54.9	171.7	0	0	0	111	F204 T212	F204-I208 HydrophobicContact CD1-CD1 4.21Å; F204-I208 HydrophobicContact CE1-CD1 4.01Å; I208-T212 PolarHBondContact O-N 3.01Å; I208-T212 PolarHBondContact O-OG1 2.95Å
209	K	59	Low	56.2	Low	135 Å²	135	101.7 Å²	101.7	59%	0.587	58%	0.575	S	S	*	*	H	α-helix	trans	-75.1	-30.5	176.4	-157.9	177	-174.8	180	0	112.6	T212 T213	K209-T212 PolarHBondContact O-OG1 3.49Å; K209-T213 PolarHBondContact O-N 3.13Å; K209-T213 PolarHBondContact O-OG1 3.07Å
210	S	58.3	Low	57.6	Low	37 Å²	37	98.8 Å²	98.8	26%	0.259	56%	0.56	S	S	.	*	H	α-helix	trans	-71.7	-36.7	176.1	69.1	0	0	0	0	112.2	G206 M207 T213 S214	G206-S210 PolarHBondContact O-N 3.34Å; G206-S210 VanDerWaalsContact O-N 3.14Å; G206-S210 PolarHBondContact O-OG 3.43Å; M207-S210 PolarHBondContact O-OG 3.38Å; M207-S210 VanDerWaalsContact O-OG 3.06Å; S210-T213 PolarHBondContact O-N 3.49Å; S210-S214 WeakPolarHBondContact O-CB 3.1Å; S210-S214 PolarHBondContact O-N 3.02Å; S210-S214 PolarHBondContact O-OG 3.36Å
211	V	54.9	Low	59.3	Low	103 Å²	103	91.2 Å²	91.2	62%	0.624	53%	0.528	S	S	*	.	H	α-helix	trans	-69.8	-36.8	179.6	175.8	0	0	0	0	112	M207	M207-V211 WeakPolarHBondContact O-CG2 3.33Å
212	T	56.4	Low	61.1	Low	101 Å²	101	89.2 Å²	89.2	62%	0.62	51%	0.513	S	S	*	.	H	α-helix	trans	-77.3	-22.5	177.8	43.1	0	0	0	0	114.3	I208 K209	I208-T212 PolarHBondContact O-N 3.01Å; I208-T212 PolarHBondContact O-OG1 2.95Å; K209-T212 PolarHBondContact O-OG1 3.49Å
213	T	54.7	Low	63.1	Low	94 Å²	94	88 Å²	88	58%	0.577	50%	0.497	S	S	*	.	H	α-helix	trans	-98.6	-19.9	177.5	48.6	0	0	0	0	114.5	K209 S210	K209-T213 PolarHBondContact O-N 3.13Å; K209-T213 PolarHBondContact O-OG1 3.07Å; S210-T213 PolarHBondContact O-N 3.49Å
214	S	54.1	Low	64.5	Low	76 Å²	76	87.5 Å²	87.5	53%	0.531	48%	0.481	S	S	.	.	H	α-helix	trans	-74.6	-32.7	178.8	-59	0	0	0	0	113.1	S210 S218	S210-S214 WeakPolarHBondContact O-CB 3.1Å; S210-S214 PolarHBondContact O-N 3.02Å; S210-S214 PolarHBondContact O-OG 3.36Å; S214-S218 PolarHBondContact O-N 3.05Å; S214-S218 PolarHBondContact O-OG 3.2Å
215	A	54.2	Low	66	Low	49 Å²	49	82.9 Å²	82.9	41%	0.405	46%	0.461	S	S	.	.	H	α-helix	trans	-68.6	-38.4	-178.2	0	0	0	0	0	113.4	G217 S218 E219	A215-G217 VanDerWaalsContact C-N 3.33Å; A215-G217 PolarHBondContact O-N 2.85Å; A215-S218 PolarHBondContact O-OG 2.95Å; A215-S218 VanDerWaalsContact O-OG 3.08Å; A215-E219 WeakPolarHBondContact O-CG 3.19Å; A215-E219 PolarHBondContact O-N 2.94Å
216	S	56.5	Low	67.6	Low	67 Å²	67	78.8 Å²	78.8	47%	0.469	45%	0.451	S	S	.	.	H	α-helix	trans	-70.4	-28.5	-179.5	-177.8	0	0	0	0	113	N220	S216-N220 WeakPolarHBondContact O-CB 3.08Å; S216-N220 PolarHBondContact O-N 3.41Å; S216-N220 PolarHBondContact O-ND2 3.5Å
217	G	61.3	Low	69.1	Low	24 Å²	24	82.1 Å²	82.1	25%	0.247	46%	0.46	C	S	.	.	H	α-helix	trans	-75.1	-40.4	178.9	0	0	0	0	0	113.2	M191 A215 L221	M191-G217 VanDerWaalsContact CE-C 3.44Å; M191-G217 VanDerWaalsContact CE-O 3.3Å; M191-G217 WeakPolarHBondContact CE-O 3.13Å; A215-G217 VanDerWaalsContact C-N 3.33Å; A215-G217 PolarHBondContact O-N 2.85Å; G217-L221 PolarHBondContact O-N 2.95Å
218	S	63.3	Low	70.8	Confident	64 Å²	64	76.1 Å²	76.1	45%	0.448	43%	0.431	S	S	.	.	H	α-helix	trans	-69.8	-42.8	179.3	50.5	0	0	0	0	112.3	S214 A215 N220 L221 T222	S214-S218 PolarHBondContact O-N 3.05Å; S214-S218 PolarHBondContact O-OG 3.2Å; A215-S218 PolarHBondContact O-OG 2.95Å; A215-S218 VanDerWaalsContact O-OG 3.08Å; S218-N220 PolarHBondContact O-N 2.85Å; S218-L221 PolarHBondContact O-N 3.41Å; S218-T222 WeakPolarHBondContact O-CG2 3.32Å; S218-T222 PolarHBondContact O-N 2.9Å; S218-T222 PolarHBondContact O-OG1 2.98Å
219	E	65.1	Low	72.4	Confident	125 Å²	125	75 Å²	75	58%	0.584	43%	0.425	S	S	*	.	H	α-helix	trans	-61.4	-43.6	177.6	-73.2	177	175.2	0	0	112.2	A215 L221 T222 L223	A215-E219 WeakPolarHBondContact O-CG 3.19Å; A215-E219 PolarHBondContact O-N 2.94Å; E219-L221 VanDerWaalsContact C-N 3.3Å; E219-L221 PolarHBondContact O-N 3.3Å; E219-T222 WeakPolarHBondContact CA-OG1 3.15Å; E219-T222 PolarHBondContact O-N 3.08Å; E219-T222 PolarHBondContact O-OG1 3.27Å; E219-L223 WeakPolarHBondContact O-CG 3.31Å; E219-L223 PolarHBondContact O-N 2.81Å
220	N	76.9	Confident	74.1	Confident	87 Å²	87	71.6 Å²	71.6	47%	0.465	42%	0.423	S	S	.	.	H	α-helix	trans	-62.1	-36.4	175.1	-82.9	-49.3	0	0	0	112.7	S216 S218 L223 I224	S216-N220 WeakPolarHBondContact O-CB 3.08Å; S216-N220 PolarHBondContact O-N 3.41Å; S216-N220 PolarHBondContact O-ND2 3.5Å; S218-N220 PolarHBondContact O-N 2.85Å; N220-L223 PolarHBondContact O-N 3.43Å; N220-I224 WeakPolarHBondContact O-CD1 3.33Å; N220-I224 VanDerWaalsContact O-CG1 3.22Å; N220-I224 WeakPolarHBondContact O-CG1 3.37Å; N220-I224 PolarHBondContact O-N 2.86Å; N220-I224 VanDerWaalsContact O-N 3.08Å
221	L	82.3	Confident	75.7	Confident	25 Å²	25	71.1 Å²	71.1	13%	0.131	42%	0.417	C	S	.	.	H	α-helix	trans	-72.3	-35.1	179.8	-147.8	140.8	0	0	0	111.6	M184 A187 R188 M191 G217 S218 E219 Q225	M184-L221 HydrophobicContact CE-CD2 4.11Å; A187-L221 HydrophobicContact CB-CD1 4.18Å; R188-L221 HydrophobicContact CG-CD1 3.9Å; R188-L221 HydrophobicContact CG-CD2 4.41Å; M191-L221 HydrophobicContact CE-CD1 4.02Å; M191-L221 HydrophobicContact SD-CD1 4.16Å; G217-L221 PolarHBondContact O-N 2.95Å; S218-L221 PolarHBondContact O-N 3.41Å; E219-L221 VanDerWaalsContact C-N 3.3Å; E219-L221 PolarHBondContact O-N 3.3Å; L221-Q225 WeakPolarHBondContact O-CB 3.42Å; L221-Q225 PolarHBondContact O-N 2.68Å
222	T	85.4	Confident	77.6	Confident	82 Å²	82	69.8 Å²	69.8	50%	0.503	40%	0.404	S	S	.	.	H	α-helix	trans	-68.7	-37.8	173.7	52.3	0	0	0	0	112.6	S218 E219 Q225 Q226	S218-T222 WeakPolarHBondContact O-CG2 3.32Å; S218-T222 PolarHBondContact O-N 2.9Å; S218-T222 PolarHBondContact O-OG1 2.98Å; E219-T222 WeakPolarHBondContact CA-OG1 3.15Å; E219-T222 PolarHBondContact O-N 3.08Å; E219-T222 PolarHBondContact O-OG1 3.27Å; T222-Q225 WeakPolarHBondContact O-CB 3.02Å; T222-Q225 PolarHBondContact O-N 3.23Å; T222-Q226 WeakPolarHBondContact O-CG 3.45Å; T222-Q226 PolarHBondContact O-N 3.05Å
223	L	88.6	Confident	79.4	Confident	91 Å²	91	68.5 Å²	68.5	48%	0.476	39%	0.391	S	S	.	.	H	α-helix	trans	-65.7	-45.8	175.4	-71.2	171.3	0	0	0	111.5	E219 N220 Q225 Q226 E227	E219-L223 WeakPolarHBondContact O-CG 3.31Å; E219-L223 PolarHBondContact O-N 2.81Å; N220-L223 PolarHBondContact O-N 3.43Å; L223-Q225 VanDerWaalsContact C-N 3.26Å; L223-Q225 PolarHBondContact O-N 3.21Å; L223-Q226 PolarHBondContact O-N 2.6Å; L223-E227 WeakPolarHBondContact O-CG 3.35Å; L223-E227 PolarHBondContact O-N 3.19Å
224	I	86.5	Confident	81.2	Confident	47 Å²	47	66.7 Å²	66.7	24%	0.241	38%	0.378	C	S	.	.	H	α-helix	trans	-63.7	-34.9	177	-62.8	164.9	0	0	0	110.7	K180 M184 N220 E227 V228	K180-I224 HydrophobicContact CB-CG2 4.38Å; M184-I224 HydrophobicContact CG-CB 4.22Å; M184-I224 HydrophobicContact CG-CG2 3.43Å; M184-I224 VanDerWaalsContact CG-CG2 3.43Å; M184-I224 HydrophobicContact SD-CG2 3.8Å; N220-I224 WeakPolarHBondContact O-CD1 3.33Å; N220-I224 VanDerWaalsContact O-CG1 3.22Å; N220-I224 WeakPolarHBondContact O-CG1 3.37Å; N220-I224 PolarHBondContact O-N 2.86Å; N220-I224 VanDerWaalsContact O-N 3.08Å; I224-E227 PolarHBondContact O-N 2.62Å; I224-V228 HydrophobicContact CG2-CG2 4.48Å; I224-V228 VanDerWaalsContact O-CG2 3.3Å; I224-V228 WeakPolarHBondContact O-CG2 3Å; I224-V228 PolarHBondContact O-N 3.44Å
225	Q	90.4	Very high	83.1	Confident	67 Å²	67	63.8 Å²	63.8	31%	0.313	36%	0.357	S	S	.	.	H	α-helix	trans	-61.8	-48.3	173.5	-176.7	66.2	50.1	0	0	111.3	M184 L221 T222 L223 E227 V228 D229	M184-Q225 HydrophobicContact CE-CB 4.1Å; L221-Q225 WeakPolarHBondContact O-CB 3.42Å; L221-Q225 PolarHBondContact O-N 2.68Å; T222-Q225 WeakPolarHBondContact O-CB 3.02Å; T222-Q225 PolarHBondContact O-N 3.23Å; L223-Q225 VanDerWaalsContact C-N 3.26Å; L223-Q225 PolarHBondContact O-N 3.21Å; Q225-E227 VanDerWaalsContact C-N 3.3Å; Q225-E227 PolarHBondContact O-N 2.84Å; Q225-V228 WeakPolarHBondContact O-CB 3.43Å; Q225-V228 PolarHBondContact O-N 3.29Å; Q225-V228 VanDerWaalsContact O-N 3.09Å; Q225-D229 PolarHBondContact NE2-OD1 3.23Å; Q225-D229 PolarHBondContact O-N 3.46Å
226	Q	91.9	Very high	84.9	Confident	128 Å²	128	68 Å²	68	60%	0.598	36%	0.363	S	S	*	.	H	α-helix	trans	-60.1	-39.6	177.3	-71.8	177.2	-14.7	0	0	112.2	T222 L223 D229 A230	T222-Q226 WeakPolarHBondContact O-CG 3.45Å; T222-Q226 PolarHBondContact O-N 3.05Å; L223-Q226 PolarHBondContact O-N 2.6Å; Q226-D229 PolarHBondContact O-N 3.24Å; Q226-A230 WeakPolarHBondContact O-CB 3.42Å; Q226-A230 PolarHBondContact O-N 2.84Å
227	E	92.6	Very high	86.6	Confident	94 Å²	94	69.8 Å²	69.8	44%	0.439	36%	0.364	S	S	.	.	H	α-helix	trans	-65	-38.1	174.3	-70.1	-179.3	154.1	0	0	112.5	K180 L223 I224 Q225 L231	K180-E227 HydrophobicContact CD-CB 4.43Å; K180-E227 IonicContact NZ-OE1 3.77Å; K180-E227 IonicContact NZ-OE2 3.96Å; K180-E227 PolarHBondContact NZ-OE2 3.31Å; L223-E227 WeakPolarHBondContact O-CG 3.35Å; L223-E227 PolarHBondContact O-N 3.19Å; I224-E227 PolarHBondContact O-N 2.62Å; Q225-E227 VanDerWaalsContact C-N 3.3Å; Q225-E227 PolarHBondContact O-N 2.84Å; E227-L231 WeakPolarHBondContact O-CB 3.39Å; E227-L231 VanDerWaalsContact O-CG 3.26Å; E227-L231 WeakPolarHBondContact O-CG 3.28Å; E227-L231 PolarHBondContact O-N 2.91Å
228	V	94	Very high	88	Confident	1 Å²	1	68.8 Å²	68.8	1%	0.006	35%	0.353	C	S	.	.	H	α-helix	trans	-65.5	-46	175	168.4	0	0	0	0	110.3	K180 K181 M184 I224 Q225 A230 L231 E232	K180-V228 HydrophobicContact CB-CG2 3.65Å; K180-V228 HydrophobicContact CD-CG2 4.33Å; K181-V228 HydrophobicContact CG-CG1 4.08Å; K181-V228 HydrophobicContact CG-CG2 4.45Å; M184-V228 HydrophobicContact SD-CG2 3.96Å; I224-V228 HydrophobicContact CG2-CG2 4.48Å; I224-V228 VanDerWaalsContact O-CG2 3.3Å; I224-V228 WeakPolarHBondContact O-CG2 3Å; I224-V228 PolarHBondContact O-N 3.44Å; Q225-V228 WeakPolarHBondContact O-CB 3.43Å; Q225-V228 PolarHBondContact O-N 3.29Å; Q225-V228 VanDerWaalsContact O-N 3.09Å; V228-A230 VanDerWaalsContact C-N 3.3Å; V228-A230 PolarHBondContact O-N 3.46Å; V228-L231 PolarHBondContact O-N 2.8Å; V228-E232 HydrophobicContact CG1-CG 4.28Å; V228-E232 WeakPolarHBondContact O-CB 3.24Å; V228-E232 WeakPolarHBondContact O-CG 3.35Å; V228-E232 PolarHBondContact O-N 3.43Å
229	D	94.2	Very high	89.4	Confident	77 Å²	77	71.5 Å²	71.5	41%	0.412	36%	0.356	S	S	.	.	H	α-helix	trans	-60.9	-40.8	179.1	-61.8	-19.4	0	0	0	111	Q225 Q226 E232 E233	Q225-D229 PolarHBondContact NE2-OD1 3.23Å; Q225-D229 PolarHBondContact O-N 3.46Å; Q226-D229 PolarHBondContact O-N 3.24Å; D229-E232 PolarHBondContact O-N 3.49Å; D229-E233 PolarHBondContact O-N 3.29Å; D229-E233 VanDerWaalsContact O-N 3.07Å
230	A	93.9	Very high	90.6	Very high	64 Å²	64	70.1 Å²	70.1	53%	0.529	35%	0.353	S	S	.	.	H	α-helix	trans	-65.6	-41.9	175.1	0	0	0	0	0	112.7	Q226 V228 E233 L234	Q226-A230 WeakPolarHBondContact O-CB 3.42Å; Q226-A230 PolarHBondContact O-N 2.84Å; V228-A230 VanDerWaalsContact C-N 3.3Å; V228-A230 PolarHBondContact O-N 3.46Å; A230-E233 PolarHBondContact O-N 3.38Å; A230-L234 PolarHBondContact O-N 2.9Å
231	L	93.6	Very high	91.2	Very high	27 Å²	27	69.1 Å²	69.1	14%	0.141	35%	0.345	C	S	.	.	H	α-helix	trans	-68.5	-34.2	176.4	-74.6	170.7	0	0	0	112.2	T173 M176 I177 K180 E227 V228 L234 S235	T173-L231 HydrophobicContact CG2-CD2 4.26Å; M176-L231 HydrophobicContact CB-CD1 4.33Å; M176-L231 HydrophobicContact CE-CD2 3.96Å; I177-L231 HydrophobicContact CD1-CB 4.14Å; I177-L231 HydrophobicContact CG1-CB 3.61Å; I177-L231 HydrophobicContact CG1-CD1 4.43Å; K180-L231 HydrophobicContact CD-CD1 3.71Å; E227-L231 WeakPolarHBondContact O-CB 3.39Å; E227-L231 VanDerWaalsContact O-CG 3.26Å; E227-L231 WeakPolarHBondContact O-CG 3.28Å; E227-L231 PolarHBondContact O-N 2.91Å; V228-L231 PolarHBondContact O-N 2.8Å; L231-L234 HydrophobicContact CD2-CD2 4.43Å; L231-L234 PolarHBondContact O-N 2.84Å; L231-S235 WeakPolarHBondContact O-CB 3.43Å; L231-S235 PolarHBondContact O-N 2.68Å
232	E	94.5	Very high	91.5	Very high	75 Å²	75	68.4 Å²	68.4	35%	0.35	34%	0.342	S	S	.	.	H	α-helix	trans	-64.8	-43	174.1	-77.1	-176.2	174.5	0	0	111.6	I177 K181 V228 D229 S235 R236	I177-E232 HydrophobicContact CD1-CG 4.26Å; I177-E232 HydrophobicContact CG2-CG 4.34Å; K181-E232 WeakPolarHBondContact CE-OE1 3.39Å; K181-E232 IonicContact NZ-OE1 2.74Å; K181-E232 PolarHBondContact NZ-OE1 2.86Å; V228-E232 HydrophobicContact CG1-CG 4.28Å; V228-E232 WeakPolarHBondContact O-CB 3.24Å; V228-E232 WeakPolarHBondContact O-CG 3.35Å; V228-E232 PolarHBondContact O-N 3.43Å; D229-E232 PolarHBondContact O-N 3.49Å; E232-S235 WeakPolarHBondContact O-CB 3.31Å; E232-S235 PolarHBondContact O-N 3.44Å; E232-R236 PolarHBondContact O-N 3.35Å
233	E	93.2	Very high	91.8	Very high	74 Å²	74	66.7 Å²	66.7	35%	0.346	34%	0.336	S	S	.	.	H	α-helix	trans	-65	-41.3	174.8	-176.8	56.5	-158.9	0	0	111.4	D229 A230 S235 R236 Q237	D229-E233 PolarHBondContact O-N 3.29Å; D229-E233 VanDerWaalsContact O-N 3.07Å; A230-E233 PolarHBondContact O-N 3.38Å; E233-S235 VanDerWaalsContact C-N 3.34Å; E233-S235 PolarHBondContact O-N 3.33Å; E233-R236 WeakPolarHBondContact O-CB 3.42Å; E233-R236 PolarHBondContact O-N 2.88Å; E233-R236 IonicContact OE1-CZ 3.12Å; E233-R236 IonicContact OE1-NE 2.61Å; E233-R236 PolarHBondContact OE1-NE 2.89Å; E233-R236 IonicContact OE1-NH2 3.16Å; E233-R236 PolarHBondContact OE1-NH2 3.38Å; E233-R236 IonicContact OE2-CZ 3.2Å; E233-R236 IonicContact OE2-NE 3.96Å; E233-R236 PolarHBondContact OE2-NE 3.17Å; E233-R236 IonicContact OE2-NH2 3.66Å; E233-R236 PolarHBondContact OE2-NH2 3.35Å; E233-Q237 WeakPolarHBondContact O-CG 3.24Å; E233-Q237 PolarHBondContact O-N 2.89Å; E233-Q237 PolarHBondContact OE1-NE2 2.95Å
234	L	92.8	Very high	91.8	Very high	57 Å²	57	67.1 Å²	67.1	30%	0.298	34%	0.339	S	S	.	.	H	α-helix	trans	-60.4	-43.2	172.4	178.6	64.1	0	0	0	111.7	T173 A230 L231 R236 Q237 L238	T173-L234 HydrophobicContact CG2-CD2 4.21Å; T173-L234 HydrophobicContact CG2-CG 4.4Å; A230-L234 PolarHBondContact O-N 2.9Å; L231-L234 HydrophobicContact CD2-CD2 4.43Å; L231-L234 PolarHBondContact O-N 2.84Å; L234-R236 VanDerWaalsContact C-N 3.29Å; L234-R236 PolarHBondContact O-N 3.47Å; L234-Q237 PolarHBondContact O-N 3.08Å; L234-L238 HydrophobicContact CD1-CD1 4.29Å; L234-L238 HydrophobicContact CD1-CG 4.23Å; L234-L238 HydrophobicContact CG-CD1 4.02Å; L234-L238 HydrophobicContact CG-CG 4.38Å; L234-L238 WeakPolarHBondContact O-CB 3.46Å; L234-L238 WeakPolarHBondContact O-CG 3.18Å; L234-L238 PolarHBondContact O-N 2.91Å
235	S	93.8	Very high	91.8	Very high	14 Å²	14	65.3 Å²	65.3	10%	0.098	33%	0.329	C	S	.	.	H	α-helix	trans	-62.1	-38.3	176.3	-177.8	0	0	0	0	111.6	L170 L231 E232 E233 F239	L170-S235 WeakPolarHBondContact CD1-O 3.26Å; L231-S235 WeakPolarHBondContact O-CB 3.43Å; L231-S235 PolarHBondContact O-N 2.68Å; E232-S235 WeakPolarHBondContact O-CB 3.31Å; E232-S235 PolarHBondContact O-N 3.44Å; E233-S235 VanDerWaalsContact C-N 3.34Å; E233-S235 PolarHBondContact O-N 3.33Å; S235-F239 VanDerWaalsContact O-CB 3.26Å; S235-F239 WeakPolarHBondContact O-CB 3.49Å; S235-F239 PolarHBondContact O-N 3.44Å
236	R	92.7	Very high	91.8	Very high	138 Å²	138	67 Å²	67	52%	0.521	33%	0.334	S	S	.	.	H	α-helix	trans	-64.7	-43.9	176.2	-167.5	177.8	75	103	4.8	111	E232 E233 L234 F239 L240	E232-R236 PolarHBondContact O-N 3.35Å; E233-R236 WeakPolarHBondContact O-CB 3.42Å; E233-R236 PolarHBondContact O-N 2.88Å; E233-R236 IonicContact OE1-CZ 3.12Å; E233-R236 IonicContact OE1-NE 2.61Å; E233-R236 PolarHBondContact OE1-NE 2.89Å; E233-R236 IonicContact OE1-NH2 3.16Å; E233-R236 PolarHBondContact OE1-NH2 3.38Å; E233-R236 IonicContact OE2-CZ 3.2Å; E233-R236 IonicContact OE2-NE 3.96Å; E233-R236 PolarHBondContact OE2-NE 3.17Å; E233-R236 IonicContact OE2-NH2 3.66Å; E233-R236 PolarHBondContact OE2-NH2 3.35Å; L234-R236 VanDerWaalsContact C-N 3.29Å; L234-R236 PolarHBondContact O-N 3.47Å; R236-F239 PolarHBondContact O-N 3.26Å; R236-L240 VanDerWaalsContact O-CG 3.31Å; R236-L240 WeakPolarHBondContact O-CG 3.23Å; R236-L240 PolarHBondContact O-N 2.87Å
237	Q	91.2	Very high	91.6	Very high	104 Å²	104	63 Å²	63	49%	0.486	32%	0.322	S	S	.	.	H	α-helix	trans	-63.6	-48.9	176.6	-70.2	175.2	5.1	0	0	111.9	E233 L234 F239 L240 E241	E233-Q237 WeakPolarHBondContact O-CG 3.24Å; E233-Q237 PolarHBondContact O-N 2.89Å; E233-Q237 PolarHBondContact OE1-NE2 2.95Å; L234-Q237 PolarHBondContact O-N 3.08Å; Q237-F239 VanDerWaalsContact C-N 3.29Å; Q237-F239 PolarHBondContact O-N 3.28Å; Q237-L240 PolarHBondContact O-N 3.39Å; Q237-E241 WeakPolarHBondContact O-CB 3.48Å; Q237-E241 PolarHBondContact O-N 2.92Å
238	L	91.1	Very high	91.3	Very high	4 Å²	4	59.1 Å²	59.1	2%	0.021	31%	0.306	C	S	.	.	H	α-helix	trans	-60.9	-37.7	177.3	-72.1	173.4	0	0	0	112.2	L166 R169 L170 L234 T242	L166-L238 HydrophobicContact CD1-CD2 3.69Å; R169-L238 HydrophobicContact CG-CD1 4.11Å; R169-L238 HydrophobicContact CG-CD2 4.34Å; L170-L238 HydrophobicContact CB-CB 4.36Å; L170-L238 HydrophobicContact CD1-CB 3.85Å; L234-L238 HydrophobicContact CD1-CD1 4.29Å; L234-L238 HydrophobicContact CD1-CG 4.23Å; L234-L238 HydrophobicContact CG-CD1 4.02Å; L234-L238 HydrophobicContact CG-CG 4.38Å; L234-L238 WeakPolarHBondContact O-CB 3.46Å; L234-L238 WeakPolarHBondContact O-CG 3.18Å; L234-L238 PolarHBondContact O-N 2.91Å; L238-T242 WeakPolarHBondContact O-CB 3.42Å; L238-T242 PolarHBondContact O-N 3.47Å; L238-T242 PolarHBondContact O-OG1 3.02Å
239	F	93.8	Very high	91	Very high	120 Å²	120	61.8 Å²	61.8	53%	0.526	32%	0.317	S	S	.	.	H	α-helix	trans	-64.9	-46.6	175.5	177.2	-97.3	0	0	0	111.8	L170 S235 R236 Q237 E241 T242 A243	L170-F239 HydrophobicContact CD1-CB 4.3Å; L170-F239 HydrophobicContact CD2-CB 4.35Å; L170-F239 HydrophobicContact CD2-CD2 4.23Å; S235-F239 VanDerWaalsContact O-CB 3.26Å; S235-F239 WeakPolarHBondContact O-CB 3.49Å; S235-F239 PolarHBondContact O-N 3.44Å; R236-F239 PolarHBondContact O-N 3.26Å; Q237-F239 VanDerWaalsContact C-N 3.29Å; Q237-F239 PolarHBondContact O-N 3.28Å; F239-E241 VanDerWaalsContact C-N 3.34Å; F239-E241 PolarHBondContact O-N 2.87Å; F239-T242 PolarHBondContact O-N 3.31Å; F239-A243 WeakPolarHBondContact O-CB 3.28Å; F239-A243 PolarHBondContact O-N 3.44Å
240	L	89.9	Confident	90.8	Very high	97 Å²	97	64.7 Å²	64.7	51%	0.508	33%	0.328	S	S	.	.	H	α-helix	trans	-62.5	-42	177	-70.7	172	0	0	0	111.6	R236 Q237 A243 D244	R236-L240 VanDerWaalsContact O-CG 3.31Å; R236-L240 WeakPolarHBondContact O-CG 3.23Å; R236-L240 PolarHBondContact O-N 2.87Å; Q237-L240 PolarHBondContact O-N 3.39Å; L240-A243 PolarHBondContact O-N 3.48Å; L240-D244 WeakPolarHBondContact O-CB 3.32Å; L240-D244 PolarHBondContact O-N 2.9Å
241	E	88.8	Confident	90.3	Very high	66 Å²	66	66.5 Å²	66.5	31%	0.308	32%	0.321	S	S	.	.	H	α-helix	trans	-64.8	-40.9	176.3	-170.1	-179.6	-174.2	0	0	111.6	L166 Q237 F239 D244 L245	L166-E241 HydrophobicContact CD2-CB 3.89Å; L166-E241 HydrophobicContact CD2-CG 3.62Å; Q237-E241 WeakPolarHBondContact O-CB 3.48Å; Q237-E241 PolarHBondContact O-N 2.92Å; F239-E241 VanDerWaalsContact C-N 3.34Å; F239-E241 PolarHBondContact O-N 2.87Å; E241-D244 PolarHBondContact O-N 2.99Å; E241-L245 WeakPolarHBondContact O-CG 3.11Å; E241-L245 PolarHBondContact O-N 3.43Å
242	T	89.4	Confident	90	Very high	10 Å²	10	66.7 Å²	66.7	6%	0.061	32%	0.322	C	S	.	.	H	α-helix	trans	-62.6	-45.6	175	-55.4	0	0	0	0	111.1	L166 E167 L238 F239 D244 L245 Y246	L166-T242 WeakPolarHBondContact CD2-OG1 3.49Å; E167-T242 HydrophobicContact CG-CG2 3.88Å; L238-T242 WeakPolarHBondContact O-CB 3.42Å; L238-T242 PolarHBondContact O-N 3.47Å; L238-T242 PolarHBondContact O-OG1 3.02Å; F239-T242 PolarHBondContact O-N 3.31Å; T242-D244 VanDerWaalsContact C-N 3.31Å; T242-D244 PolarHBondContact O-N 3.36Å; T242-L245 PolarHBondContact O-N 3.41Å; T242-Y246 HydrophobicContact CG2-CD2 3.93Å; T242-Y246 HydrophobicContact CG2-CE2 3.87Å; T242-Y246 WeakPolarHBondContact O-CD2 3.37Å; T242-Y246 PolarHBondContact O-N 2.71Å
243	A	91.5	Very high	89.7	Confident	46 Å²	46	68 Å²	68	38%	0.38	33%	0.328	S	S	.	.	H	α-helix	trans	-61	-39.4	176.5	0	0	0	0	0	112.2	F239 L240 Y246 A247	F239-A243 WeakPolarHBondContact O-CB 3.28Å; F239-A243 PolarHBondContact O-N 3.44Å; L240-A243 PolarHBondContact O-N 3.48Å; A243-Y246 PolarHBondContact O-N 2.89Å; A243-A247 PolarHBondContact O-N 3.33Å
244	D	87.3	Confident	89.4	Confident	99 Å²	99	69.1 Å²	69.1	53%	0.529	33%	0.33	S	S	.	.	H	α-helix	trans	-67.2	-39.1	176.8	-170.4	53.2	0	0	0	112.6	L240 E241 T242 A247 T248	L240-D244 WeakPolarHBondContact O-CB 3.32Å; L240-D244 PolarHBondContact O-N 2.9Å; E241-D244 PolarHBondContact O-N 2.99Å; T242-D244 VanDerWaalsContact C-N 3.31Å; T242-D244 PolarHBondContact O-N 3.36Å; D244-A247 PolarHBondContact O-N 3.28Å; D244-T248 WeakPolarHBondContact O-CB 3.45Å; D244-T248 PolarHBondContact O-N 3.04Å; D244-T248 PolarHBondContact O-OG1 3.38Å
245	L	87.6	Confident	89.1	Confident	9 Å²	9	67.7 Å²	67.7	5%	0.047	33%	0.325	C	S	.	.	H	α-helix	trans	-63.3	-41.7	173.5	-70.8	-176.8	0	0	0	111.9	V158 I163 L166 E241 T242 T248 K249	V158-L245 HydrophobicContact CG1-CB 4.27Å; V158-L245 HydrophobicContact CG1-CD2 3.96Å; V158-L245 HydrophobicContact CG2-CD2 3.71Å; I163-L245 HydrophobicContact CG1-CB 4.02Å; I163-L245 HydrophobicContact CG1-CD1 4.4Å; L166-L245 HydrophobicContact CB-CD1 4.43Å; L166-L245 HydrophobicContact CD2-CD1 3.65Å; L166-L245 HydrophobicContact CD2-CG 4.46Å; E241-L245 WeakPolarHBondContact O-CG 3.11Å; E241-L245 PolarHBondContact O-N 3.43Å; T242-L245 PolarHBondContact O-N 3.41Å; L245-T248 PolarHBondContact O-N 3.01Å; L245-K249 PolarHBondContact O-N 2.92Å
246	Y	90.2	Very high	88.7	Confident	102 Å²	102	73.9 Å²	73.9	40%	0.4	35%	0.35	S	S	.	.	H	α-helix	trans	-63.1	-45.2	174.4	-89.1	-70.8	0	0	0	112.3	I163 E167 T242 A243 T248 K249 E250	I163-Y246 HydrophobicContact CG2-CD2 4.16Å; I163-Y246 HydrophobicContact CG2-CE1 4.05Å; I163-Y246 HydrophobicContact CG2-CE2 3.49Å; I163-Y246 VanDerWaalsContact CG2-CE2 3.49Å; I163-Y246 VanDerWaalsContact CG2-CZ 3.43Å; E167-Y246 WeakPolarHBondContact OE1-CE2 3.25Å; E167-Y246 VanDerWaalsContact OE1-CZ 3.26Å; E167-Y246 PolarHBondContact OE1-OH 3.48Å; T242-Y246 HydrophobicContact CG2-CD2 3.93Å; T242-Y246 HydrophobicContact CG2-CE2 3.87Å; T242-Y246 WeakPolarHBondContact O-CD2 3.37Å; T242-Y246 PolarHBondContact O-N 2.71Å; A243-Y246 PolarHBondContact O-N 2.89Å; Y246-T248 VanDerWaalsContact C-N 3.27Å; Y246-T248 PolarHBondContact O-N 2.84Å; Y246-K249 PolarHBondContact O-N 3.09Å; Y246-E250 PolarHBondContact O-N 3.09Å
247	A	87.6	Confident	88.7	Confident	44 Å²	44	70.3 Å²	70.3	36%	0.364	34%	0.344	S	S	.	.	H	α-helix	trans	-60.6	-39.2	175.1	0	0	0	0	0	111.5	A243 D244 E250 R251	A243-A247 PolarHBondContact O-N 3.33Å; D244-A247 PolarHBondContact O-N 3.28Å; A247-E250 PolarHBondContact O-N 2.69Å; A247-R251 WeakPolarHBondContact O-CG 3.2Å; A247-R251 PolarHBondContact O-N 3.14Å
248	T	86	Confident	88.6	Confident	14 Å²	14	74.4 Å²	74.4	9%	0.086	36%	0.36	C	S	.	.	H	α-helix	trans	-65.8	-42.3	176.1	-59.9	0	0	0	0	111.6	V158 D244 L245 Y246 R251 I252	V158-T248 HydrophobicContact CG2-CG2 3.62Å; D244-T248 WeakPolarHBondContact O-CB 3.45Å; D244-T248 PolarHBondContact O-N 3.04Å; D244-T248 PolarHBondContact O-OG1 3.38Å; L245-T248 PolarHBondContact O-N 3.01Å; Y246-T248 VanDerWaalsContact C-N 3.27Å; Y246-T248 PolarHBondContact O-N 2.84Å; T248-R251 WeakPolarHBondContact O-CB 3.41Å; T248-R251 PolarHBondContact O-N 3.19Å; T248-R251 VanDerWaalsContact O-N 3.16Å; T248-I252 HydrophobicContact CG2-CD1 4.41Å; T248-I252 WeakPolarHBondContact O-CG1 3.39Å; T248-I252 PolarHBondContact O-N 2.76Å
249	K	88.5	Confident	88.3	Confident	56 Å²	56	80.4 Å²	80.4	24%	0.243	39%	0.386	C	S	.	.	H	α-helix	trans	-59.8	-46	174.6	-179.8	177.8	171.5	179.8	0	111.8	D160 I163 L245 Y246 R251 I252 E253	D160-K249 VanDerWaalsContact OD1-CE 3.25Å; D160-K249 WeakPolarHBondContact OD1-CE 3.39Å; D160-K249 IonicContact OD1-NZ 2.63Å; D160-K249 PolarHBondContact OD1-NZ 2.98Å; I163-K249 HydrophobicContact CD1-CB 4.11Å; I163-K249 HydrophobicContact CD1-CD 3.62Å; I163-K249 HydrophobicContact CD1-CG 4.44Å; L245-K249 PolarHBondContact O-N 2.92Å; Y246-K249 PolarHBondContact O-N 3.09Å; K249-R251 VanDerWaalsContact C-N 3.26Å; K249-R251 PolarHBondContact O-N 3.33Å; K249-I252 WeakPolarHBondContact O-CB 3.42Å; K249-I252 PolarHBondContact O-N 2.8Å; K249-I252 VanDerWaalsContact O-N 3.09Å; K249-E253 WeakPolarHBondContact CE-OE1 3.33Å; K249-E253 PolarHBondContact O-N 2.87Å
250	E	88.6	Confident	87.9	Confident	138 Å²	138	74.9 Å²	74.9	65%	0.645	36%	0.363	S	S	*	.	H	α-helix	trans	-58.5	-39.7	175.2	-171	-174.1	172.8	0	0	111.2	Y246 A247 E253 Y254	Y246-E250 PolarHBondContact O-N 3.09Å; A247-E250 PolarHBondContact O-N 2.69Å; E250-E253 PolarHBondContact O-N 2.96Å; E250-Y254 WeakPolarHBondContact O-CB 3.44Å; E250-Y254 PolarHBondContact O-N 3.11Å
251	R	85.1	Confident	87.7	Confident	103 Å²	103	76.3 Å²	76.3	39%	0.389	37%	0.365	S	S	.	.	H	α-helix	trans	-66.8	-36.5	175.2	-68.2	-143.9	-67.4	177.4	-3.9	113.3	L155 A247 T248 K249 Y254 S255	L155-R251 HydrophobicContact CD2-CB 4.02Å; A247-R251 WeakPolarHBondContact O-CG 3.2Å; A247-R251 PolarHBondContact O-N 3.14Å; T248-R251 WeakPolarHBondContact O-CB 3.41Å; T248-R251 PolarHBondContact O-N 3.19Å; T248-R251 VanDerWaalsContact O-N 3.16Å; K249-R251 VanDerWaalsContact C-N 3.26Å; K249-R251 PolarHBondContact O-N 3.33Å; R251-Y254 PolarHBondContact O-N 3.28Å; R251-S255 WeakPolarHBondContact O-CB 3.45Å; R251-S255 PolarHBondContact O-N 3.05Å
252	I	85.6	Confident	87.6	Confident	31 Å²	31	80 Å²	80	16%	0.159	38%	0.377	C	S	.	.	H	α-helix	trans	-62.7	-46.7	173.5	-67.4	168.6	0	0	0	109.6	L155 V158 T248 K249 S255 K256	L155-I252 HydrophobicContact CD2-CG1 3.94Å; V158-I252 HydrophobicContact CB-CD1 4.35Å; T248-I252 HydrophobicContact CG2-CD1 4.41Å; T248-I252 WeakPolarHBondContact O-CG1 3.39Å; T248-I252 PolarHBondContact O-N 2.76Å; K249-I252 WeakPolarHBondContact O-CB 3.42Å; K249-I252 PolarHBondContact O-N 2.8Å; K249-I252 VanDerWaalsContact O-N 3.09Å; I252-S255 PolarHBondContact O-N 2.95Å; I252-S255 PolarHBondContact O-OG 3.31Å; I252-K256 PolarHBondContact O-N 3.39Å
253	E	88.4	Confident	87	Confident	103 Å²	103	82.2 Å²	82.2	48%	0.481	39%	0.386	S	S	.	.	H	α-helix	trans	-62.3	-44.4	176.9	-69.9	176.4	-170.6	0	0	111.6	K249 E250 S255 K256	K249-E253 WeakPolarHBondContact CE-OE1 3.33Å; K249-E253 PolarHBondContact O-N 2.87Å; E250-E253 PolarHBondContact O-N 2.96Å; E253-S255 VanDerWaalsContact C-N 3.3Å; E253-S255 PolarHBondContact O-N 3.02Å; E253-K256 WeakPolarHBondContact O-CB 3.34Å; E253-K256 PolarHBondContact O-N 3.2Å; E253-K256 VanDerWaalsContact O-N 3.13Å
254	Y	87.7	Confident	86.6	Confident	96 Å²	96	81.3 Å²	81.3	38%	0.376	38%	0.375	S	S	.	.	H	α-helix	trans	-57	-43	173.9	178.4	-100.4	0	0	0	111.9	E250 R251 K256 T257 K259 G260 F263	E250-Y254 WeakPolarHBondContact O-CB 3.44Å; E250-Y254 PolarHBondContact O-N 3.11Å; R251-Y254 PolarHBondContact O-N 3.28Å; Y254-K256 PolarHBondContact O-N 3.37Å; Y254-T257 WeakPolarHBondContact O-CB 3.27Å; Y254-T257 PolarHBondContact O-N 2.99Å; Y254-T257 PolarHBondContact O-OG1 3.35Å; Y254-K259 HydrophobicContact CE2-CD 4.07Å; Y254-K259 HydrophobicContact CE2-CG 4.41Å; Y254-K259 WeakPolarHBondContact OH-CD 3.38Å; Y254-K259 WeakPolarHBondContact OH-CE 3.21Å; Y254-K259 WeakPolarHBondContact OH-CG 3.43Å; Y254-G260 WeakPolarHBondContact O-CA 2.95Å; Y254-F263 WeakPolarHBondContact OH-CD2 3.14Å
255	S	85.8	Confident	86.5	Confident	28 Å²	28	83.7 Å²	83.7	20%	0.196	38%	0.38	C	S	.	.	H	α-helix	trans	-61.5	-27.4	-180	80.3	0	0	0	0	113.4	R251 I252 E253 T257 K261	R251-S255 WeakPolarHBondContact O-CB 3.45Å; R251-S255 PolarHBondContact O-N 3.05Å; I252-S255 PolarHBondContact O-N 2.95Å; I252-S255 PolarHBondContact O-OG 3.31Å; E253-S255 VanDerWaalsContact C-N 3.3Å; E253-S255 PolarHBondContact O-N 3.02Å; S255-T257 VanDerWaalsContact C-N 3.35Å; S255-K261 PolarHBondContact O-N 3.15Å
256	K	87.1	Confident	85.8	Confident	144 Å²	144	85.5 Å²	85.5	63%	0.626	39%	0.39	S	S	*	.	H	α-helix	trans	-76	-22.7	177.5	-65.1	172.3	-176.9	174.2	0	112.6	I252 E253 Y254 K261	I252-K256 PolarHBondContact O-N 3.39Å; E253-K256 WeakPolarHBondContact O-CB 3.34Å; E253-K256 PolarHBondContact O-N 3.2Å; E253-K256 VanDerWaalsContact O-N 3.13Å; Y254-K256 PolarHBondContact O-N 3.37Å; K256-K261 WeakPolarHBondContact O-CE 3.41Å
257	T	92.4	Very high	84.9	Confident	63 Å²	63	80.7 Å²	80.7	39%	0.387	37%	0.371	S	S	.	.	S	Bend	trans	-67.2	158.4	178	72.3	0	0	0	0	111.9	Y254 S255 K259 G260 K261	Y254-T257 WeakPolarHBondContact O-CB 3.27Å; Y254-T257 PolarHBondContact O-N 2.99Å; Y254-T257 PolarHBondContact O-OG1 3.35Å; S255-T257 VanDerWaalsContact C-N 3.35Å; T257-K259 VanDerWaalsContact C-N 3.26Å; T257-K259 PolarHBondContact O-N 3.06Å; T257-G260 PolarHBondContact O-N 3.38Å; T257-G260 VanDerWaalsContact O-N 3.11Å; T257-G260 PolarHBondContact OG1-N 3.48Å; T257-K261 WeakPolarHBondContact O-CG 3.37Å; T257-K261 PolarHBondContact O-N 3.16Å
258	F	89	Confident	84.5	Confident	189 Å²	189	83.3 Å²	83.3	83%	0.829	37%	0.373	S	S	*	.	H	α-helix	trans	-57.2	-40.1	174.9	-75	-79.5	0	0	0	112.7	K261 Y262	F258-K261 PolarHBondContact O-N 2.94Å; F258-Y262 PolarHBondContact O-N 3.25Å; F258-Y262 VanDerWaalsContact O-N 3.09Å
259	K	83.9	Confident	84	Confident	131 Å²	131	88.9 Å²	88.9	57%	0.57	40%	0.396	S	S	*	.	H	α-helix	trans	-63.3	-45.1	175.1	-171.2	-177.8	174.4	-174	0	110.9	Y254 T257 Y262 F263	Y254-K259 HydrophobicContact CE2-CD 4.07Å; Y254-K259 HydrophobicContact CE2-CG 4.41Å; Y254-K259 WeakPolarHBondContact OH-CD 3.38Å; Y254-K259 WeakPolarHBondContact OH-CE 3.21Å; Y254-K259 WeakPolarHBondContact OH-CG 3.43Å; T257-K259 VanDerWaalsContact C-N 3.26Å; T257-K259 PolarHBondContact O-N 3.06Å; K259-Y262 PolarHBondContact O-N 2.86Å; K259-F263 HydrophobicContact CD-CE2 4.42Å; K259-F263 HydrophobicContact CG-CD2 3.96Å; K259-F263 HydrophobicContact CG-CE2 3.79Å; K259-F263 VanDerWaalsContact O-CD2 3.23Å; K259-F263 WeakPolarHBondContact O-CD2 3.22Å; K259-F263 PolarHBondContact O-N 2.85Å; K259-F263 VanDerWaalsContact O-N 3.09Å
260	G	85.4	Confident	83	Confident	3 Å²	3	90.1 Å²	90.1	3%	0.031	40%	0.402	C	S	.	.	H	α-helix	trans	-60.7	-46	176.1	0	0	0	0	0	113.1	Y254 T257 Y262 F263 N264	Y254-G260 WeakPolarHBondContact O-CA 2.95Å; T257-G260 PolarHBondContact O-N 3.38Å; T257-G260 VanDerWaalsContact O-N 3.11Å; T257-G260 PolarHBondContact OG1-N 3.48Å; G260-Y262 VanDerWaalsContact C-N 3.32Å; G260-Y262 PolarHBondContact O-N 3.15Å; G260-F263 PolarHBondContact O-N 3.12Å; G260-N264 WeakPolarHBondContact O-CB 3.34Å; G260-N264 PolarHBondContact O-N 3.48Å
261	K	86	Confident	82.3	Confident	128 Å²	128	85.1 Å²	85.1	56%	0.557	38%	0.381	S	S	*	.	H	α-helix	trans	-58.8	-41.7	176.3	-71.7	-179	-179.3	-179.7	0	112.5	S255 K256 T257 F258 N264 F265	S255-K261 PolarHBondContact O-N 3.15Å; K256-K261 WeakPolarHBondContact O-CE 3.41Å; T257-K261 WeakPolarHBondContact O-CG 3.37Å; T257-K261 PolarHBondContact O-N 3.16Å; F258-K261 PolarHBondContact O-N 2.94Å; K261-N264 PolarHBondContact O-N 3.37Å; K261-F265 PolarHBondContact O-N 3.29Å
262	Y	85.9	Confident	82	Confident	142 Å²	142	86.1 Å²	86.1	56%	0.557	39%	0.393	S	S	*	.	H	α-helix	trans	-61.3	-50	174.5	172.5	-95.7	0	0	0	112.2	F258 K259 G260 N264 F265 L266	F258-Y262 PolarHBondContact O-N 3.25Å; F258-Y262 VanDerWaalsContact O-N 3.09Å; K259-Y262 PolarHBondContact O-N 2.86Å; G260-Y262 VanDerWaalsContact C-N 3.32Å; G260-Y262 PolarHBondContact O-N 3.15Å; Y262-N264 VanDerWaalsContact C-N 3.29Å; Y262-N264 PolarHBondContact O-N 3.42Å; Y262-F265 PolarHBondContact O-N 2.71Å; Y262-L266 HydrophobicContact CE1-CD2 4.3Å; Y262-L266 WeakPolarHBondContact O-CB 3.33Å; Y262-L266 PolarHBondContact O-N 3.27Å
263	F	77.2	Confident	81.4	Confident	57 Å²	57	90 Å²	90	25%	0.25	41%	0.407	C	S	.	.	H	α-helix	trans	-65.2	-32.4	178.2	-81	-72.5	0	0	0	112.8	Y150 Y254 K259 G260 L266 G267	Y150-F263 HydrophobicContact CD1-CB 4.33Å; Y150-F263 HydrophobicContact CD1-CD1 4.29Å; Y150-F263 HydrophobicContact CE1-CD1 4.16Å; Y254-F263 WeakPolarHBondContact OH-CD2 3.14Å; K259-F263 HydrophobicContact CD-CE2 4.42Å; K259-F263 HydrophobicContact CG-CD2 3.96Å; K259-F263 HydrophobicContact CG-CE2 3.79Å; K259-F263 VanDerWaalsContact O-CD2 3.23Å; K259-F263 WeakPolarHBondContact O-CD2 3.22Å; K259-F263 PolarHBondContact O-N 2.85Å; K259-F263 VanDerWaalsContact O-N 3.09Å; G260-F263 PolarHBondContact O-N 3.12Å; F263-L266 HydrophobicContact CD1-CD2 4.35Å; F263-L266 PolarHBondContact O-N 2.82Å; F263-G267 PolarHBondContact O-N 3.41Å
264	N	84.1	Confident	80.6	Confident	27 Å²	27	85.7 Å²	85.7	14%	0.144	39%	0.388	C	S	.	.	H	α-helix	trans	-65.5	-47.4	174.7	-169.1	31.1	0	0	0	111.5	M151 S152 G260 K261 Y262 L266 G267 Y268	M151-N264 WeakPolarHBondContact CA-OD1 3.44Å; S152-N264 PolarHBondContact N-OD1 3.41Å; S152-N264 PolarHBondContact OG-ND2 3.41Å; S152-N264 PolarHBondContact OG-OD1 2.95Å; G260-N264 WeakPolarHBondContact O-CB 3.34Å; G260-N264 PolarHBondContact O-N 3.48Å; K261-N264 PolarHBondContact O-N 3.37Å; Y262-N264 VanDerWaalsContact C-N 3.29Å; Y262-N264 PolarHBondContact O-N 3.42Å; N264-L266 VanDerWaalsContact C-N 3.33Å; N264-L266 PolarHBondContact O-N 2.9Å; N264-G267 WeakPolarHBondContact O-CA 3.38Å; N264-G267 PolarHBondContact O-N 3.34Å; N264-G267 VanDerWaalsContact O-N 3.1Å; N264-Y268 WeakPolarHBondContact O-CD2 3.22Å; N264-Y268 PolarHBondContact O-N 2.98Å; N264-Y268 VanDerWaalsContact O-N 3.15Å
265	F	84.1	Confident	80.2	Confident	149 Å²	149	85.6 Å²	85.6	65%	0.654	40%	0.397	S	S	*	.	H	α-helix	trans	-58.2	-45.7	173.8	176.6	-101.1	0	0	0	111.8	K261 Y262 G267 Y268 F269	K261-F265 PolarHBondContact O-N 3.29Å; Y262-F265 PolarHBondContact O-N 2.71Å; F265-G267 PolarHBondContact O-N 2.98Å; F265-Y268 PolarHBondContact O-N 3.49Å; F265-F269 PolarHBondContact O-N 3.18Å
266	L	72.4	Confident	79.8	Confident	47 Å²	47	90.5 Å²	90.5	25%	0.246	41%	0.412	C	S	.	.	H	α-helix	trans	-61.2	-35.7	175.8	-169.1	67.7	0	0	0	111.9	Y262 F263 N264 F269 F270	Y262-L266 HydrophobicContact CE1-CD2 4.3Å; Y262-L266 WeakPolarHBondContact O-CB 3.33Å; Y262-L266 PolarHBondContact O-N 3.27Å; F263-L266 HydrophobicContact CD1-CD2 4.35Å; F263-L266 PolarHBondContact O-N 2.82Å; N264-L266 VanDerWaalsContact C-N 3.33Å; N264-L266 PolarHBondContact O-N 2.9Å; L266-F269 PolarHBondContact O-N 3.05Å; L266-F270 HydrophobicContact CD1-CD2 4.22Å; L266-F270 HydrophobicContact CD1-CE2 3.77Å; L266-F270 HydrophobicContact CD2-CD2 4.4Å; L266-F270 HydrophobicContact CD2-CE2 3.82Å; L266-F270 HydrophobicContact CG-CD2 3.74Å; L266-F270 HydrophobicContact CG-CE2 3.5Å; L266-F270 VanDerWaalsContact O-CD2 3.25Å; L266-F270 WeakPolarHBondContact O-CD2 3.44Å; L266-F270 PolarHBondContact O-N 2.96Å
267	G	73.1	Confident	79	Confident	1 Å²	1	85.9 Å²	85.9	1%	0.01	39%	0.392	C	S	.	.	H	α-helix	trans	-59.3	-43.2	173.5	0	0	0	0	0	113.2	F263 N264 F265 F270 S271	F263-G267 PolarHBondContact O-N 3.41Å; N264-G267 WeakPolarHBondContact O-CA 3.38Å; N264-G267 PolarHBondContact O-N 3.34Å; N264-G267 VanDerWaalsContact O-N 3.1Å; F265-G267 PolarHBondContact O-N 2.98Å; G267-F270 PolarHBondContact O-N 3.22Å; G267-S271 WeakPolarHBondContact O-CB 3.38Å; G267-S271 PolarHBondContact O-N 2.95Å
268	Y	78.3	Confident	78.2	Confident	100 Å²	100	84.5 Å²	84.5	39%	0.392	38%	0.382	S	S	.	.	H	α-helix	trans	-63.8	-44.2	174.8	-72.7	-71.4	0	0	0	112.3	M151 N264 F265 F270 S271 I272	M151-Y268 HydrophobicContact CE-CE1 4.45Å; M151-Y268 HydrophobicContact CG-CD1 4.33Å; M151-Y268 HydrophobicContact CG-CE1 3.82Å; M151-Y268 HydrophobicContact CG-CE2 4.25Å; M151-Y268 HydrophobicContact SD-CD1 3.72Å; M151-Y268 HydrophobicContact SD-CE1 3.42Å; M151-Y268 WeakPolarHBondContact SD-CE1 3.29Å; N264-Y268 WeakPolarHBondContact O-CD2 3.22Å; N264-Y268 PolarHBondContact O-N 2.98Å; N264-Y268 VanDerWaalsContact O-N 3.15Å; F265-Y268 PolarHBondContact O-N 3.49Å; Y268-F270 PolarHBondContact O-N 3.15Å; Y268-S271 WeakPolarHBondContact O-CB 3.49Å; Y268-S271 PolarHBondContact O-N 3.02Å; Y268-I272 WeakPolarHBondContact O-CG1 3.2Å; Y268-I272 PolarHBondContact O-N 3.48Å; Y268-I272 VanDerWaalsContact O-N 3.08Å
269	F	76.1	Confident	77.9	Confident	131 Å²	131	80.8 Å²	80.8	58%	0.575	37%	0.365	S	S	*	.	H	α-helix	trans	-59.4	-48.3	175.9	178	-95.1	0	0	0	111.6	F265 L266 S271 I272 Y273	F265-F269 PolarHBondContact O-N 3.18Å; L266-F269 PolarHBondContact O-N 3.05Å; F269-S271 VanDerWaalsContact C-N 3.31Å; F269-S271 PolarHBondContact O-N 3.39Å; F269-I272 PolarHBondContact O-N 2.84Å; F269-Y273 PolarHBondContact O-N 3.23Å; F269-Y273 VanDerWaalsContact O-N 3.1Å
270	F	67.4	Low	77.4	Confident	82 Å²	82	77.6 Å²	77.6	36%	0.36	35%	0.353	S	S	.	.	H	α-helix	trans	-64.9	-34.3	176.5	-80.6	-59.1	0	0	0	112.7	L266 G267 Y268 Y273 C274	L266-F270 HydrophobicContact CD1-CD2 4.22Å; L266-F270 HydrophobicContact CD1-CE2 3.77Å; L266-F270 HydrophobicContact CD2-CD2 4.4Å; L266-F270 HydrophobicContact CD2-CE2 3.82Å; L266-F270 HydrophobicContact CG-CD2 3.74Å; L266-F270 HydrophobicContact CG-CE2 3.5Å; L266-F270 VanDerWaalsContact O-CD2 3.25Å; L266-F270 WeakPolarHBondContact O-CD2 3.44Å; L266-F270 PolarHBondContact O-N 2.96Å; G267-F270 PolarHBondContact O-N 3.22Å; Y268-F270 PolarHBondContact O-N 3.15Å; F270-Y273 PolarHBondContact O-N 2.92Å; F270-C274 WeakPolarHBondContact O-CB 3.48Å; F270-C274 PolarHBondContact O-N 3.47Å; F270-C274 PolarHBondContact O-SG 2.69Å
271	S	73.9	Confident	76.9	Confident	32 Å²	32	77.5 Å²	77.5	22%	0.224	35%	0.352	C	S	.	.	H	α-helix	trans	-60.4	-48.5	175.5	-178.8	0	0	0	0	111.4	G267 Y268 F269 Y273 C274 V275	G267-S271 WeakPolarHBondContact O-CB 3.38Å; G267-S271 PolarHBondContact O-N 2.95Å; Y268-S271 WeakPolarHBondContact O-CB 3.49Å; Y268-S271 PolarHBondContact O-N 3.02Å; F269-S271 VanDerWaalsContact C-N 3.31Å; F269-S271 PolarHBondContact O-N 3.39Å; S271-Y273 VanDerWaalsContact C-N 3.33Å; S271-Y273 PolarHBondContact O-N 3.14Å; S271-C274 PolarHBondContact O-N 2.94Å; S271-C274 VanDerWaalsContact O-N 3.14Å; S271-V275 WeakPolarHBondContact O-CG2 3.31Å; S271-V275 PolarHBondContact O-N 3.2Å
272	I	77.8	Confident	76.7	Confident	125 Å²	125	74 Å²	74	64%	0.641	34%	0.342	S	S	*	.	H	α-helix	trans	-58.7	-46.6	176.1	-65.2	166.9	0	0	0	110.4	Y268 F269 C274 V275 W276	Y268-I272 WeakPolarHBondContact O-CG1 3.2Å; Y268-I272 PolarHBondContact O-N 3.48Å; Y268-I272 VanDerWaalsContact O-N 3.08Å; F269-I272 PolarHBondContact O-N 2.84Å; I272-C274 VanDerWaalsContact C-N 3.35Å; I272-C274 PolarHBondContact O-N 3.22Å; I272-V275 PolarHBondContact O-N 2.74Å; I272-W276 WeakPolarHBondContact O-CB 3.4Å; I272-W276 PolarHBondContact O-N 3.46Å
273	Y	72.8	Confident	76.4	Confident	111 Å²	111	69.1 Å²	69.1	44%	0.435	33%	0.325	S	S	.	.	H	α-helix	trans	-60.1	-41.4	176	173.4	-100.8	0	0	0	112.7	F269 F270 S271 W276 K277	F269-Y273 PolarHBondContact O-N 3.23Å; F269-Y273 VanDerWaalsContact O-N 3.1Å; F270-Y273 PolarHBondContact O-N 2.92Å; S271-Y273 VanDerWaalsContact C-N 3.33Å; S271-Y273 PolarHBondContact O-N 3.14Å; Y273-W276 PolarHBondContact O-N 2.93Å; Y273-K277 HydrophobicContact CE1-CD 4.2Å; Y273-K277 VanDerWaalsContact O-CB 3.3Å; Y273-K277 WeakPolarHBondContact O-CB 3.31Å; Y273-K277 PolarHBondContact O-N 3.31Å
274	C	72.5	Confident	76.5	Confident	13 Å²	13	67.9 Å²	67.9	9%	0.088	32%	0.321	C	S	.	.	H	α-helix	trans	-68.5	-42	-179.9	-68.7	0	0	0	0	111.9	A143 F270 S271 I272 K277 I278	A143-C274 VanDerWaalsContact CA-SG 3.55Å; A143-C274 HydrophobicContact CB-CB 4.07Å; A143-C274 WeakPolarHBondContact O-CB 3.12Å; A143-C274 PolarHBondContact O-SG 2.9Å; A143-C274 VanDerWaalsContact O-SG 3.35Å; F270-C274 WeakPolarHBondContact O-CB 3.48Å; F270-C274 PolarHBondContact O-N 3.47Å; F270-C274 PolarHBondContact O-SG 2.69Å; S271-C274 PolarHBondContact O-N 2.94Å; S271-C274 VanDerWaalsContact O-N 3.14Å; I272-C274 VanDerWaalsContact C-N 3.35Å; I272-C274 PolarHBondContact O-N 3.22Å; C274-K277 PolarHBondContact O-N 3.02Å; C274-I278 WeakPolarHBondContact O-CB 3.31Å; C274-I278 VanDerWaalsContact O-CG1 3.29Å; C274-I278 WeakPolarHBondContact O-CG1 3.21Å; C274-I278 PolarHBondContact O-N 3.18Å
275	V	79.1	Confident	76.4	Confident	95 Å²	95	68.6 Å²	68.6	58%	0.576	32%	0.324	S	S	*	.	H	α-helix	trans	-60.9	-46.9	173.6	172.6	0	0	0	0	110.3	S271 I272 K277 I278 F279	S271-V275 WeakPolarHBondContact O-CG2 3.31Å; S271-V275 PolarHBondContact O-N 3.2Å; I272-V275 PolarHBondContact O-N 2.74Å; V275-K277 VanDerWaalsContact C-N 3.35Å; V275-K277 PolarHBondContact O-N 3.49Å; V275-I278 PolarHBondContact O-N 2.81Å; V275-F279 WeakPolarHBondContact O-CB 3.32Å; V275-F279 PolarHBondContact O-N 2.94Å
276	W	76.8	Confident	76.4	Confident	130 Å²	130	66.3 Å²	66.3	49%	0.492	32%	0.322	S	S	.	.	H	α-helix	trans	-59.8	-42.9	175.3	178.6	-100.6	0	0	0	112.5	I272 Y273 F279 M280	I272-W276 WeakPolarHBondContact O-CB 3.4Å; I272-W276 PolarHBondContact O-N 3.46Å; Y273-W276 PolarHBondContact O-N 2.93Å; W276-F279 PolarHBondContact O-N 2.6Å; W276-M280 HydrophobicContact CD2-CE 4.47Å; W276-M280 HydrophobicContact CD2-CG 4.32Å; W276-M280 HydrophobicContact CH2-CE 3.39Å; W276-M280 HydrophobicContact CZ2-CE 3.09Å; W276-M280 HydrophobicContact CZ2-CG 4.33Å; W276-M280 HydrophobicContact CZ3-CE 4.18Å; W276-M280 WeakPolarHBondContact O-CB 3.35Å; W276-M280 WeakPolarHBondContact O-CG 3.31Å; W276-M280 PolarHBondContact O-N 3.08Å
277	K	70.7	Confident	76.7	Confident	48 Å²	48	71.2 Å²	71.2	21%	0.209	34%	0.342	C	S	.	.	H	α-helix	trans	-65.6	-41.7	178.6	-169.9	178.5	179.3	-176.9	0	111.9	S139 Y273 C274 V275 M280 A281 F407	S139-K277 PolarHBondContact OG-NZ 3.05Å; S139-K277 VanDerWaalsContact OG-NZ 3.08Å; Y273-K277 HydrophobicContact CE1-CD 4.2Å; Y273-K277 VanDerWaalsContact O-CB 3.3Å; Y273-K277 WeakPolarHBondContact O-CB 3.31Å; Y273-K277 PolarHBondContact O-N 3.31Å; C274-K277 PolarHBondContact O-N 3.02Å; V275-K277 VanDerWaalsContact C-N 3.35Å; V275-K277 PolarHBondContact O-N 3.49Å; K277-M280 PolarHBondContact O-N 3.08Å; K277-A281 VanDerWaalsContact O-CB 3.28Å; K277-A281 WeakPolarHBondContact O-CB 3.38Å; K277-A281 PolarHBondContact O-N 3.08Å; K277-F407 HydrophobicContact CB-CZ 4.43Å; K277-F407 HydrophobicContact CD-CE1 4.29Å; K277-F407 HydrophobicContact CD-CE2 4.08Å; K277-F407 HydrophobicContact CD-CZ 3.71Å; K277-F407 HydrophobicContact CG-CE1 4Å; K277-F407 HydrophobicContact CG-CZ 3.86Å
278	I	75.9	Confident	76.5	Confident	34 Å²	34	75.6 Å²	75.6	17%	0.174	37%	0.365	C	S	.	.	H	α-helix	trans	-63.4	-44.6	174.4	-70.5	168.3	0	0	0	110.6	C274 V275 A281 T282 F407 L408 A411	C274-I278 WeakPolarHBondContact O-CB 3.31Å; C274-I278 VanDerWaalsContact O-CG1 3.29Å; C274-I278 WeakPolarHBondContact O-CG1 3.21Å; C274-I278 PolarHBondContact O-N 3.18Å; V275-I278 PolarHBondContact O-N 2.81Å; I278-A281 PolarHBondContact O-N 3.36Å; I278-T282 WeakPolarHBondContact O-CB 3.47Å; I278-T282 PolarHBondContact O-N 3.44Å; I278-T282 PolarHBondContact O-OG1 2.82Å; I278-F407 HydrophobicContact CG1-CE1 3.95Å; I278-F407 HydrophobicContact CG1-CZ 4.21Å; I278-L408 HydrophobicContact CG2-CD1 3.88Å; I278-A411 HydrophobicContact CD1-CB 4.07Å; I278-A411 HydrophobicContact CG1-CB 4.23Å
279	F	82.7	Confident	75.9	Confident	110 Å²	110	78.9 Å²	78.9	48%	0.482	38%	0.377	S	S	.	.	H	α-helix	trans	-61.3	-48.2	176.4	177.9	-107.2	0	0	0	111.9	V275 W276 T282 I283	V275-F279 WeakPolarHBondContact O-CB 3.32Å; V275-F279 PolarHBondContact O-N 2.94Å; W276-F279 PolarHBondContact O-N 2.6Å; F279-T282 WeakPolarHBondContact O-CB 3.34Å; F279-T282 PolarHBondContact O-N 2.9Å; F279-I283 HydrophobicContact CD1-CD1 3.95Å; F279-I283 HydrophobicContact CE1-CD1 3.33Å; F279-I283 HydrophobicContact CE1-CG1 4.42Å; F279-I283 HydrophobicContact CE2-CD1 4.07Å; F279-I283 HydrophobicContact CZ-CD1 3.42Å; F279-I283 VanDerWaalsContact CZ-CD1 3.42Å; F279-I283 HydrophobicContact CZ-CG1 4.32Å; F279-I283 PolarHBondContact O-N 3.21Å
280	M	74.2	Confident	75.1	Confident	64 Å²	64	75.1 Å²	75.1	32%	0.315	36%	0.364	S	S	.	.	H	α-helix	trans	-64.5	-42.1	178	-78.8	-63.8	178.5	0	0	112.7	W276 K277 T282 I283 N284	W276-M280 HydrophobicContact CD2-CE 4.47Å; W276-M280 HydrophobicContact CD2-CG 4.32Å; W276-M280 HydrophobicContact CH2-CE 3.39Å; W276-M280 HydrophobicContact CZ2-CE 3.09Å; W276-M280 HydrophobicContact CZ2-CG 4.33Å; W276-M280 HydrophobicContact CZ3-CE 4.18Å; W276-M280 WeakPolarHBondContact O-CB 3.35Å; W276-M280 WeakPolarHBondContact O-CG 3.31Å; W276-M280 PolarHBondContact O-N 3.08Å; K277-M280 PolarHBondContact O-N 3.08Å; M280-T282 VanDerWaalsContact C-N 3.26Å; M280-T282 PolarHBondContact O-N 3.5Å; M280-I283 PolarHBondContact O-N 3.42Å; M280-N284 WeakPolarHBondContact O-CB 3.19Å; M280-N284 PolarHBondContact O-N 2.97Å; M280-N284 PolarHBondContact O-OD1 3.07Å
281	A	73.9	Confident	74.5	Confident	2 Å²	2	73.3 Å²	73.3	2%	0.017	37%	0.369	C	S	.	.	H	α-helix	trans	-60.2	-39.2	174.1	0	0	0	0	0	111.2	K277 I278 N284 I285 D404 F407	K277-A281 VanDerWaalsContact O-CB 3.28Å; K277-A281 WeakPolarHBondContact O-CB 3.38Å; K277-A281 PolarHBondContact O-N 3.08Å; I278-A281 PolarHBondContact O-N 3.36Å; A281-N284 PolarHBondContact O-N 3.13Å; A281-I285 WeakPolarHBondContact O-CD1 3.48Å; A281-I285 WeakPolarHBondContact O-CG1 3.36Å; A281-I285 PolarHBondContact O-N 3.46Å; A281-D404 HydrophobicContact CB-CB 4.25Å; A281-F407 HydrophobicContact CB-CD1 4.05Å; A281-F407 HydrophobicContact CB-CE1 4.35Å
282	T	82.3	Confident	73.6	Confident	54 Å²	54	81.6 Å²	81.6	33%	0.331	40%	0.401	S	S	.	.	H	α-helix	trans	-64.1	-45.8	176.1	-54.2	0	0	0	0	111.3	I278 F279 M280 I285 V286	I278-T282 WeakPolarHBondContact O-CB 3.47Å; I278-T282 PolarHBondContact O-N 3.44Å; I278-T282 PolarHBondContact O-OG1 2.82Å; F279-T282 WeakPolarHBondContact O-CB 3.34Å; F279-T282 PolarHBondContact O-N 2.9Å; M280-T282 VanDerWaalsContact C-N 3.26Å; M280-T282 PolarHBondContact O-N 3.5Å; T282-I285 PolarHBondContact O-N 2.73Å; T282-V286 HydrophobicContact CG2-CG2 4.38Å; T282-V286 WeakPolarHBondContact O-CB 3.49Å; T282-V286 VanDerWaalsContact O-CG2 3.27Å; T282-V286 WeakPolarHBondContact O-CG2 3.49Å; T282-V286 PolarHBondContact O-N 3.41Å
283	I	79.4	Confident	72.3	Confident	39 Å²	39	78.9 Å²	78.9	20%	0.2	39%	0.39	C	S	.	.	H	α-helix	trans	-61.2	-45.9	175.6	-73.4	179.8	0	0	0	111.2	F279 M280 I285 V286 F287	F279-I283 HydrophobicContact CD1-CD1 3.95Å; F279-I283 HydrophobicContact CE1-CD1 3.33Å; F279-I283 HydrophobicContact CE1-CG1 4.42Å; F279-I283 HydrophobicContact CE2-CD1 4.07Å; F279-I283 HydrophobicContact CZ-CD1 3.42Å; F279-I283 VanDerWaalsContact CZ-CD1 3.42Å; F279-I283 HydrophobicContact CZ-CG1 4.32Å; F279-I283 PolarHBondContact O-N 3.21Å; M280-I283 PolarHBondContact O-N 3.42Å; I283-I285 VanDerWaalsContact C-N 3.27Å; I283-I285 PolarHBondContact O-N 3.5Å; I283-V286 PolarHBondContact O-N 3.31Å; I283-F287 HydrophobicContact CB-CD2 4.41Å; I283-F287 HydrophobicContact CG2-CD2 3.89Å; I283-F287 WeakPolarHBondContact O-CB 3.46Å; I283-F287 WeakPolarHBondContact O-CD2 3.41Å; I283-F287 PolarHBondContact O-N 2.89Å
284	N	79.7	Confident	71.5	Confident	31 Å²	31	75.1 Å²	75.1	17%	0.166	38%	0.377	C	S	.	.	H	α-helix	trans	-59.3	-40.6	-179.6	-69.5	-10.4	0	0	0	111.5	M280 A281 D288 R289 D404	M280-N284 WeakPolarHBondContact O-CB 3.19Å; M280-N284 PolarHBondContact O-N 2.97Å; M280-N284 PolarHBondContact O-OD1 3.07Å; A281-N284 PolarHBondContact O-N 3.13Å; N284-D288 VanDerWaalsContact O-CA 3.28Å; N284-D288 WeakPolarHBondContact O-CA 3.37Å; N284-D288 PolarHBondContact O-N 3.27Å; N284-D288 VanDerWaalsContact O-N 3.15Å; N284-R289 PolarHBondContact O-N 3.06Å; N284-R289 PolarHBondContact OD1-O 3.21Å; N284-D404 WeakPolarHBondContact CB-OD2 3.39Å; N284-D404 PolarHBondContact ND2-OD2 2.71Å
285	I	81.1	Confident	70.8	Confident	43 Å²	43	78.8 Å²	78.8	22%	0.221	40%	0.401	C	S	.	.	H	α-helix	trans	-69.7	-46.4	177.7	-66	163.7	0	0	0	111.5	A281 T282 I283 D404 V405 L408	A281-I285 WeakPolarHBondContact O-CD1 3.48Å; A281-I285 WeakPolarHBondContact O-CG1 3.36Å; A281-I285 PolarHBondContact O-N 3.46Å; T282-I285 PolarHBondContact O-N 2.73Å; I283-I285 VanDerWaalsContact C-N 3.27Å; I283-I285 PolarHBondContact O-N 3.5Å; I285-D404 HydrophobicContact CD1-CB 4.22Å; I285-D404 HydrophobicContact CG1-CB 4.09Å; I285-V405 HydrophobicContact CD1-CB 4.47Å; I285-V405 HydrophobicContact CD1-CG2 3.9Å; I285-V405 HydrophobicContact CG1-CG2 3.94Å; I285-V405 HydrophobicContact CG2-CG2 4.47Å; I285-L408 HydrophobicContact CD1-CB 4.25Å; I285-L408 HydrophobicContact CD1-CD2 3.77Å
286	V	83.8	Confident	69.6	Low	100 Å²	100	76.6 Å²	76.6	61%	0.606	39%	0.388	S	S	*	.	H	α-helix	trans	-70.5	-41.5	-174.7	170.8	0	0	0	0	112	T282 I283	T282-V286 HydrophobicContact CG2-CG2 4.38Å; T282-V286 WeakPolarHBondContact O-CB 3.49Å; T282-V286 VanDerWaalsContact O-CG2 3.27Å; T282-V286 WeakPolarHBondContact O-CG2 3.49Å; T282-V286 PolarHBondContact O-N 3.41Å; I283-V286 PolarHBondContact O-N 3.31Å
287	F	79.4	Confident	68.8	Low	151 Å²	151	71.3 Å²	71.3	66%	0.662	37%	0.37	S	S	*	.	T	Hydrogen-bonded Turn	trans	-100.1	7.5	-175	-65.4	-78.6	0	0	0	113.6	I283 R289	I283-F287 HydrophobicContact CB-CD2 4.41Å; I283-F287 HydrophobicContact CG2-CD2 3.89Å; I283-F287 WeakPolarHBondContact O-CB 3.46Å; I283-F287 WeakPolarHBondContact O-CD2 3.41Å; I283-F287 PolarHBondContact O-N 2.89Å; F287-R289 HydrophobicContact CB-CB 4.37Å; F287-R289 PolarHBondContact O-N 3.41Å
288	D	68.7	Low	68.5	Low	93 Å²	93	75.3 Å²	75.3	50%	0.497	38%	0.384	S	S	.	.	T	Hydrogen-bonded Turn	trans	45.4	36.3	-174.1	-153.2	19.5	0	0	0	112.8	N284 V290 R401	N284-D288 VanDerWaalsContact O-CA 3.28Å; N284-D288 WeakPolarHBondContact O-CA 3.37Å; N284-D288 PolarHBondContact O-N 3.27Å; N284-D288 VanDerWaalsContact O-N 3.15Å; D288-V290 PolarHBondContact O-N 3.36Å; D288-R401 IonicContact OD1-CZ 3.67Å; D288-R401 IonicContact OD1-NH1 2.75Å; D288-R401 PolarHBondContact OD1-NH1 3.07Å; D288-R401 IonicContact OD2-NH1 3.87Å; D288-R401 PolarHBondContact OD2-NH1 3.29Å
289	R	65.9	Low	68	Low	169 Å²	169	75.1 Å²	75.1	64%	0.638	39%	0.39	S	S	*	.			trans	-88	103.8	-172.2	-167.5	178.8	-178.1	-178.6	1.2	108.7	N284 F287 G291	N284-R289 PolarHBondContact O-N 3.06Å; N284-R289 PolarHBondContact OD1-O 3.21Å; F287-R289 HydrophobicContact CB-CB 4.37Å; F287-R289 PolarHBondContact O-N 3.41Å; R289-G291 PolarHBondContact O-N 3.04Å
290	V	58.3	Low	67.2	Low	52 Å²	52	71.2 Å²	71.2	32%	0.315	37%	0.374	S	S	.	.			trans	-76.3	117.9	172.4	-172.3	0	0	0	0	108.6	D288 K292 N397	D288-V290 PolarHBondContact O-N 3.36Å; V290-K292 PolarHBondContact O-N 3.5Å; V290-K292 VanDerWaalsContact O-N 3.15Å; V290-N397 WeakPolarHBondContact CG1-OD1 3.23Å; V290-N397 HydrophobicContact CG2-CB 4.14Å
291	G	55.6	Low	66.8	Low	44 Å²	44	71.6 Å²	71.6	45%	0.454	38%	0.375	S	S	.	.			trans	-53.4	116.8	-179	0	0	0	0	0	111.7	R289	R289-G291 PolarHBondContact O-N 3.04Å
292	K	54.8	Low	66.7	Low	205 Å²	205	76.7 Å²	76.7	89%	0.891	40%	0.401	S	S	*	.	S	Bend	trans	-87.1	-16.1	179.3	-69.5	-172.5	178.4	-178.3	0	113.4	V290	V290-K292 PolarHBondContact O-N 3.5Å; V290-K292 VanDerWaalsContact O-N 3.15Å
293	T	51.4	Low	66.2	Low	69 Å²	69	77.7 Å²	77.7	42%	0.423	41%	0.407	S	S	.	.	S	Bend	trans	-149.3	139.4	-179.4	52.1	0	0	0	0	109.2	R298	T293-R298 WeakPolarHBondContact OG1-CD 3.18Å
294	D	55.9	Low	65.8	Low	31 Å²	31	76.8 Å²	76.8	17%	0.166	40%	0.404	C	S	.	.			trans	-63.4	142.2	176.8	59.6	-63.3	0	0	0	111.5	V296 T297 R298	D294-V296 PolarHBondContact O-N 3.22Å; D294-T297 VanDerWaalsContact CG-CB 3.43Å; D294-T297 PolarHBondContact O-N 2.83Å; D294-T297 WeakPolarHBondContact OD1-CB 3.44Å; D294-T297 PolarHBondContact OD1-OG1 3Å; D294-T297 WeakPolarHBondContact OD2-CB 3.16Å; D294-T297 PolarHBondContact OD2-N 3.34Å; D294-T297 PolarHBondContact OD2-OG1 3.38Å; D294-R298 PolarHBondContact O-N 2.98Å
295	P	56.2	Low	65.5	Low	91 Å²	91	81.8 Å²	81.8	59%	0.591	43%	0.43	S	S	*	.	H	α-helix	trans	-64.7	-24.1	-174.2	23	-32	0	0	0	113	G299	P295-G299 PolarHBondContact O-N 3.43Å
296	V	55.5	Low	65.4	Low	48 Å²	48	89.4 Å²	89.4	29%	0.291	46%	0.458	S	S	.	.	H	α-helix	trans	-72.1	-51.5	176.9	-178.1	0	0	0	0	109.9	D294 R298 G299 I300 L324	D294-V296 PolarHBondContact O-N 3.22Å; V296-R298 VanDerWaalsContact C-N 3.33Å; V296-R298 PolarHBondContact O-N 2.99Å; V296-G299 PolarHBondContact O-N 2.96Å; V296-G299 VanDerWaalsContact O-N 3.1Å; V296-I300 HydrophobicContact CG1-CD1 4.09Å; V296-I300 WeakPolarHBondContact O-CG1 3.34Å; V296-I300 PolarHBondContact O-N 2.95Å; V296-L324 HydrophobicContact CG1-CD1 4.2Å; V296-L324 HydrophobicContact CG2-CD1 4.21Å; V296-L324 HydrophobicContact CG2-CD2 3.93Å
297	T	59.2	Low	65.2	Low	19 Å²	19	89.5 Å²	89.5	12%	0.117	45%	0.454	C	S	.	.	H	α-helix	trans	-60.3	-42.1	176.3	-63.3	0	0	0	0	111.8	D294 G299 I300 E301	D294-T297 VanDerWaalsContact CG-CB 3.43Å; D294-T297 PolarHBondContact O-N 2.83Å; D294-T297 WeakPolarHBondContact OD1-CB 3.44Å; D294-T297 PolarHBondContact OD1-OG1 3Å; D294-T297 WeakPolarHBondContact OD2-CB 3.16Å; D294-T297 PolarHBondContact OD2-N 3.34Å; D294-T297 PolarHBondContact OD2-OG1 3.38Å; T297-G299 VanDerWaalsContact C-N 3.31Å; T297-G299 PolarHBondContact O-N 3.09Å; T297-I300 PolarHBondContact O-N 2.88Å; T297-E301 WeakPolarHBondContact O-CG 3.36Å; T297-E301 PolarHBondContact O-N 3.34Å
298	R	65	Low	64.5	Low	132 Å²	132	85.5 Å²	85.5	50%	0.498	46%	0.455	S	S	.	.	H	α-helix	trans	-60.8	-39.7	174.4	-161.8	106.1	176.5	132.9	-1.5	112.3	T293 D294 V296 E301 I302	T293-R298 WeakPolarHBondContact OG1-CD 3.18Å; D294-R298 PolarHBondContact O-N 2.98Å; V296-R298 VanDerWaalsContact C-N 3.33Å; V296-R298 PolarHBondContact O-N 2.99Å; R298-E301 IonicContact NH1-OE2 3.5Å; R298-E301 PolarHBondContact O-N 3.31Å; R298-I302 HydrophobicContact CG-CD1 4.33Å; R298-I302 WeakPolarHBondContact O-CD1 3.39Å; R298-I302 VanDerWaalsContact O-CG1 3.27Å; R298-I302 WeakPolarHBondContact O-CG1 3.02Å; R298-I302 PolarHBondContact O-N 3.43Å; R298-I302 VanDerWaalsContact O-N 3.1Å
299	G	65.9	Low	64.8	Low	31 Å²	31	85.6 Å²	85.6	32%	0.32	46%	0.455	S	S	.	.	H	α-helix	trans	-65.4	-40.7	175.9	0	0	0	0	0	112.6	P295 V296 T297 I302 T303	P295-G299 PolarHBondContact O-N 3.43Å; V296-G299 PolarHBondContact O-N 2.96Å; V296-G299 VanDerWaalsContact O-N 3.1Å; T297-G299 VanDerWaalsContact C-N 3.31Å; T297-G299 PolarHBondContact O-N 3.09Å; G299-I302 PolarHBondContact O-N 3.34Å; G299-T303 WeakPolarHBondContact O-CB 3.32Å; G299-T303 PolarHBondContact O-N 3.25Å; G299-T303 PolarHBondContact O-OG1 3.33Å
300	I	65.1	Low	64.5	Low	28 Å²	28	87.1 Å²	87.1	14%	0.144	47%	0.469	C	S	.	.	H	α-helix	trans	-64.8	-45.5	175.4	-64.7	166.8	0	0	0	110.3	V296 T297 I302 T303 V304 V313 I320	V296-I300 HydrophobicContact CG1-CD1 4.09Å; V296-I300 WeakPolarHBondContact O-CG1 3.34Å; V296-I300 PolarHBondContact O-N 2.95Å; T297-I300 PolarHBondContact O-N 2.88Å; I300-I302 PolarHBondContact O-N 2.91Å; I300-T303 PolarHBondContact O-N 2.93Å; I300-V304 HydrophobicContact CG2-CG2 4.22Å; I300-V304 WeakPolarHBondContact O-CG2 3.32Å; I300-V304 PolarHBondContact O-N 3.36Å; I300-V313 HydrophobicContact CG2-CG1 4.26Å; I300-I320 HydrophobicContact CD1-CB 4.3Å; I300-I320 HydrophobicContact CD1-CD1 4.21Å; I300-I320 HydrophobicContact CD1-CG2 3.95Å
301	E	66.6	Low	64.7	Low	71 Å²	71	88.5 Å²	88.5	33%	0.332	47%	0.471	S	S	.	.	H	α-helix	trans	-56.5	-47	176.2	-77	176.6	175.6	0	0	112.3	T297 R298 T303 N305 V313	T297-E301 WeakPolarHBondContact O-CG 3.36Å; T297-E301 PolarHBondContact O-N 3.34Å; R298-E301 IonicContact NH1-OE2 3.5Å; R298-E301 PolarHBondContact O-N 3.31Å; E301-T303 VanDerWaalsContact C-N 3.35Å; E301-N305 WeakPolarHBondContact O-CB 3.35Å; E301-N305 VanDerWaalsContact O-CG 3.27Å; E301-N305 PolarHBondContact O-N 3.42Å; E301-N305 PolarHBondContact O-ND2 3.34Å; E301-V313 HydrophobicContact CG-CG1 4.11Å
302	I	71.9	Confident	65.3	Low	109 Å²	109	91 Å²	91	56%	0.559	47%	0.474	S	S	*	.	H	α-helix	trans	-64.2	-42.3	178.3	-67.1	164.6	0	0	0	110.6	R298 G299 I300 N305 Y306	R298-I302 HydrophobicContact CG-CD1 4.33Å; R298-I302 WeakPolarHBondContact O-CD1 3.39Å; R298-I302 VanDerWaalsContact O-CG1 3.27Å; R298-I302 WeakPolarHBondContact O-CG1 3.02Å; R298-I302 PolarHBondContact O-N 3.43Å; R298-I302 VanDerWaalsContact O-N 3.1Å; G299-I302 PolarHBondContact O-N 3.34Å; I300-I302 PolarHBondContact O-N 2.91Å; I302-N305 PolarHBondContact O-N 2.87Å; I302-Y306 VanDerWaalsContact O-CB 3.26Å; I302-Y306 WeakPolarHBondContact O-CB 3.47Å; I302-Y306 PolarHBondContact O-N 2.83Å
303	T	71.1	Confident	65.7	Low	76 Å²	76	82.9 Å²	82.9	47%	0.466	44%	0.442	S	S	.	.	H	α-helix	trans	-66.8	-41.9	-178.2	-56.6	0	0	0	0	111.7	G299 I300 E301 Y306 L307	G299-T303 WeakPolarHBondContact O-CB 3.32Å; G299-T303 PolarHBondContact O-N 3.25Å; G299-T303 PolarHBondContact O-OG1 3.33Å; I300-T303 PolarHBondContact O-N 2.93Å; E301-T303 VanDerWaalsContact C-N 3.35Å; T303-Y306 PolarHBondContact O-N 3.39Å; T303-L307 HydrophobicContact CG2-CD1 3.77Å; T303-L307 WeakPolarHBondContact O-CB 3.4Å; T303-L307 WeakPolarHBondContact O-CG 3.49Å; T303-L307 PolarHBondContact O-N 2.89Å
304	V	71.6	Confident	66.3	Low	20 Å²	20	85.8 Å²	85.8	12%	0.121	45%	0.448	C	S	.	.	H	α-helix	trans	-69.1	-42	178.3	174.6	0	0	0	0	111.2	I300 Y306 L307 G308 I309 F311 V313	I300-V304 HydrophobicContact CG2-CG2 4.22Å; I300-V304 WeakPolarHBondContact O-CG2 3.32Å; I300-V304 PolarHBondContact O-N 3.36Å; V304-Y306 VanDerWaalsContact C-N 3.31Å; V304-Y306 PolarHBondContact O-N 3.41Å; V304-L307 PolarHBondContact O-N 3.09Å; V304-G308 PolarHBondContact O-N 3.26Å; V304-G308 VanDerWaalsContact O-N 3.13Å; V304-I309 WeakPolarHBondContact CG1-O 3.31Å; V304-F311 HydrophobicContact CG1-CB 4.05Å; V304-F311 HydrophobicContact CG2-CB 4.31Å; V304-F311 HydrophobicContact CG2-CD1 4.25Å; V304-V313 HydrophobicContact CB-CG2 3.82Å; V304-V313 HydrophobicContact CG1-CG2 3.5Å; V304-V313 HydrophobicContact CG2-CG2 3.99Å
305	N	73.1	Confident	66.8	Low	135 Å²	135	89 Å²	89	72%	0.722	46%	0.461	S	S	*	.	H	α-helix	trans	-64.5	-35.1	175.2	-74.6	-25.1	0	0	0	112.5	E301 I302	E301-N305 WeakPolarHBondContact O-CB 3.35Å; E301-N305 VanDerWaalsContact O-CG 3.27Å; E301-N305 PolarHBondContact O-N 3.42Å; E301-N305 PolarHBondContact O-ND2 3.34Å; I302-N305 PolarHBondContact O-N 2.87Å
306	Y	79.1	Confident	67.4	Low	203 Å²	203	90.1 Å²	90.1	80%	0.796	45%	0.454	S	S	*	.	H	α-helix	trans	-72.8	-36.4	177.8	-175.7	-99.2	0	0	0	112.9	I302 T303 V304	I302-Y306 VanDerWaalsContact O-CB 3.26Å; I302-Y306 WeakPolarHBondContact O-CB 3.47Å; I302-Y306 PolarHBondContact O-N 2.83Å; T303-Y306 PolarHBondContact O-N 3.39Å; V304-Y306 VanDerWaalsContact C-N 3.31Å; V304-Y306 PolarHBondContact O-N 3.41Å
307	L	78.4	Confident	67.6	Low	103 Å²	103	88.5 Å²	88.5	54%	0.539	44%	0.444	S	S	.	.	H	α-helix	trans	-85.2	-9	-178.5	-71.6	166.9	0	0	0	113.8	T303 V304 I309	T303-L307 HydrophobicContact CG2-CD1 3.77Å; T303-L307 WeakPolarHBondContact O-CB 3.4Å; T303-L307 WeakPolarHBondContact O-CG 3.49Å; T303-L307 PolarHBondContact O-N 2.89Å; V304-L307 PolarHBondContact O-N 3.09Å; L307-I309 HydrophobicContact CB-CD1 3.89Å; L307-I309 HydrophobicContact CB-CG1 3.96Å; L307-I309 HydrophobicContact CD1-CD1 4.34Å; L307-I309 PolarHBondContact O-N 3.45Å; L307-I309 VanDerWaalsContact O-N 3.08Å
308	G	65.6	Low	67.6	Low	66 Å²	66	89 Å²	89	68%	0.68	45%	0.445	S	S	*	.	T	Hydrogen-bonded Turn	trans	62.5	16.3	177.5	0	0	0	0	0	114.4	V304	V304-G308 PolarHBondContact O-N 3.26Å; V304-G308 VanDerWaalsContact O-N 3.13Å
309	I	73.7	Confident	67.7	Low	96 Å²	96	86.4 Å²	86.4	49%	0.492	44%	0.439	S	S	.	.			trans	-80.2	130.4	179.8	-57.8	171.4	0	0	0	107.4	V304 L307 F311	V304-I309 WeakPolarHBondContact CG1-O 3.31Å; L307-I309 HydrophobicContact CB-CD1 3.89Å; L307-I309 HydrophobicContact CB-CG1 3.96Å; L307-I309 HydrophobicContact CD1-CD1 4.34Å; L307-I309 PolarHBondContact O-N 3.45Å; L307-I309 VanDerWaalsContact O-N 3.08Å; I309-F311 HydrophobicContact CB-CB 4.43Å; I309-F311 HydrophobicContact CG2-CB 3.93Å; I309-F311 PolarHBondContact O-N 3.33Å
310	Q	61.2	Low	67.7	Low	201 Å²	201	88 Å²	88	94%	0.939	44%	0.439	S	S	*	.			trans	-72.4	59.3	167.9	-65.9	-157.1	-7.9	0	0	110.7
311	F	61.9	Low	67.6	Low	81 Å²	81	86.9 Å²	86.9	36%	0.355	43%	0.434	S	S	.	.			trans	-84.1	129.5	176	-158.4	-113.5	0	0	0	107.4	V304 I309 V313 W316	V304-F311 HydrophobicContact CG1-CB 4.05Å; V304-F311 HydrophobicContact CG2-CB 4.31Å; V304-F311 HydrophobicContact CG2-CD1 4.25Å; I309-F311 HydrophobicContact CB-CB 4.43Å; I309-F311 HydrophobicContact CG2-CB 3.93Å; I309-F311 PolarHBondContact O-N 3.33Å; F311-V313 WeakPolarHBondContact O-CG2 3.46Å; F311-V313 PolarHBondContact O-N 2.97Å; F311-W316 HydrophobicContact CD1-CB 4.06Å; F311-W316 AromaticContact CD1-CD1 3.85Å; F311-W316 HydrophobicContact CD1-CG 4.06Å; F311-W316 HydrophobicContact CE1-CB 3.27Å; F311-W316 AromaticContact CE1-CD1 3.3Å; F311-W316 AromaticContact CE1-CD2 3.82Å; F311-W316 HydrophobicContact CE1-CD2 3.82Å; F311-W316 AromaticContact CE1-CG 3.15Å; F311-W316 HydrophobicContact CE1-CG 3.15Å; F311-W316 AromaticContact CE1-NE1 3.97Å; F311-W316 AromaticContact CE2-CD1 3.76Å; F311-W316 HydrophobicContact CE2-CD2 4.29Å; F311-W316 AromaticContact CE2-CE2 3.94Å; F311-W316 HydrophobicContact CE2-CG 4.18Å; F311-W316 AromaticContact CE2-NE1 3.6Å; F311-W316 HydrophobicContact CZ-CB 3.87Å; F311-W316 AromaticContact CZ-CD1 3.23Å; F311-W316 AromaticContact CZ-CD2 3.38Å; F311-W316 HydrophobicContact CZ-CD2 3.38Å; F311-W316 AromaticContact CZ-CE2 3.5Å; F311-W316 VanDerWaalsContact CZ-CE2 3.5Å; F311-W316 HydrophobicContact CZ-CE3 4.14Å; F311-W316 AromaticContact CZ-CG 3.22Å; F311-W316 HydrophobicContact CZ-CG 3.22Å; F311-W316 HydrophobicContact CZ-CZ2 4.31Å; F311-W316 AromaticContact CZ-NE1 3.39Å
312	D	68.4	Low	67.4	Low	95 Å²	95	85.8 Å²	85.8	51%	0.508	43%	0.428	S	S	.	.			trans	-68.6	85.9	174	-172.5	-7.4	0	0	0	109	K314 F315 W316	D312-K314 PolarHBondContact O-N 3.03Å; D312-K314 PolarHBondContact OD1-N 3.3Å; D312-F315 HydrophobicContact CB-CB 4.09Å; D312-F315 PolarHBondContact O-N 2.88Å; D312-F315 PolarHBondContact OD1-N 3.05Å; D312-F315 WeakPolarHBondContact OD2-CB 3.49Å; D312-W316 PolarHBondContact O-N 3.03Å
313	V	63.6	Low	67.2	Low	35 Å²	35	85.5 Å²	85.5	21%	0.212	43%	0.427	C	S	.	.	H	α-helix	trans	-54.1	-37.3	-178.7	-175.8	0	0	0	0	109.5	I300 E301 V304 F311 S317	I300-V313 HydrophobicContact CG2-CG1 4.26Å; E301-V313 HydrophobicContact CG-CG1 4.11Å; V304-V313 HydrophobicContact CB-CG2 3.82Å; V304-V313 HydrophobicContact CG1-CG2 3.5Å; V304-V313 HydrophobicContact CG2-CG2 3.99Å; F311-V313 WeakPolarHBondContact O-CG2 3.46Å; F311-V313 PolarHBondContact O-N 2.97Å; V313-S317 WeakPolarHBondContact O-CA 3.43Å; V313-S317 WeakPolarHBondContact O-CB 3.41Å; V313-S317 PolarHBondContact O-N 3.18Å; V313-S317 PolarHBondContact O-OG 3.45Å
314	K	62.4	Low	66.7	Low	130 Å²	130	85 Å²	85	57%	0.565	42%	0.42	S	S	*	.	H	α-helix	trans	-69.6	-46.5	-175.5	-161	-179.6	178.6	-165	0	111	D312 S317 Q318 E382	D312-K314 PolarHBondContact O-N 3.03Å; D312-K314 PolarHBondContact OD1-N 3.3Å; K314-S317 PolarHBondContact O-OG 3.47Å; K314-Q318 WeakPolarHBondContact O-CB 3.5Å; K314-Q318 PolarHBondContact O-N 2.84Å; K314-E382 WeakPolarHBondContact CE-OE1 3.5Å; K314-E382 IonicContact NZ-OE1 2.76Å; K314-E382 PolarHBondContact NZ-OE1 3.43Å
315	F	67.8	Low	66.1	Low	99 Å²	99	84.3 Å²	84.3	43%	0.434	42%	0.416	S	S	.	.	H	α-helix	trans	-64.4	-47.9	177.3	179.9	-95.7	0	0	0	112.2	D312 H319	D312-F315 HydrophobicContact CB-CB 4.09Å; D312-F315 PolarHBondContact O-N 2.88Å; D312-F315 PolarHBondContact OD1-N 3.05Å; D312-F315 WeakPolarHBondContact OD2-CB 3.49Å; F315-H319 AromaticContact CD2-CE1 3.85Å; F315-H319 AromaticContact CE1-CE1 3.97Å; F315-H319 AromaticContact CE2-CE1 3.37Å; F315-H319 WeakPolarHBondContact CE2-CE1 3.23Å; F315-H319 AromaticContact CZ-CE1 3.43Å; F315-H319 VanDerWaalsContact CZ-CE1 3.43Å; F315-H319 WeakPolarHBondContact CZ-CE1 3.36Å; F315-H319 AromaticContact CZ-ND1 3.95Å; F315-H319 AromaticContact CZ-NE2 3.96Å; F315-H319 PolarHBondContact O-N 3.27Å; F315-H319 PolarHBondContact O-ND1 3.29Å
316	W	68.5	Low	65.5	Low	115 Å²	115	79.2 Å²	79.2	44%	0.436	40%	0.396	S	S	.	.	H	α-helix	trans	-79.2	-36	-174.5	-76.7	98	0	0	0	114.1	F311 D312 Q318 H319 I320	F311-W316 HydrophobicContact CD1-CB 4.06Å; F311-W316 AromaticContact CD1-CD1 3.85Å; F311-W316 HydrophobicContact CD1-CG 4.06Å; F311-W316 HydrophobicContact CE1-CB 3.27Å; F311-W316 AromaticContact CE1-CD1 3.3Å; F311-W316 AromaticContact CE1-CD2 3.82Å; F311-W316 HydrophobicContact CE1-CD2 3.82Å; F311-W316 AromaticContact CE1-CG 3.15Å; F311-W316 HydrophobicContact CE1-CG 3.15Å; F311-W316 AromaticContact CE1-NE1 3.97Å; F311-W316 AromaticContact CE2-CD1 3.76Å; F311-W316 HydrophobicContact CE2-CD2 4.29Å; F311-W316 AromaticContact CE2-CE2 3.94Å; F311-W316 HydrophobicContact CE2-CG 4.18Å; F311-W316 AromaticContact CE2-NE1 3.6Å; F311-W316 HydrophobicContact CZ-CB 3.87Å; F311-W316 AromaticContact CZ-CD1 3.23Å; F311-W316 AromaticContact CZ-CD2 3.38Å; F311-W316 HydrophobicContact CZ-CD2 3.38Å; F311-W316 AromaticContact CZ-CE2 3.5Å; F311-W316 VanDerWaalsContact CZ-CE2 3.5Å; F311-W316 HydrophobicContact CZ-CE3 4.14Å; F311-W316 AromaticContact CZ-CG 3.22Å; F311-W316 HydrophobicContact CZ-CG 3.22Å; F311-W316 HydrophobicContact CZ-CZ2 4.31Å; F311-W316 AromaticContact CZ-NE1 3.39Å; D312-W316 PolarHBondContact O-N 3.03Å; W316-Q318 PolarHBondContact O-N 3.08Å; W316-H319 PolarHBondContact O-N 3.37Å; W316-I320 HydrophobicContact CB-CD1 4.44Å; W316-I320 WeakPolarHBondContact O-CB 3.23Å; W316-I320 WeakPolarHBondContact O-CG1 3.32Å; W316-I320 PolarHBondContact O-N 3.11Å
317	S	60.4	Low	64.7	Low	13 Å²	13	74.3 Å²	74.3	9%	0.091	38%	0.382	C	S	.	.	H	α-helix	trans	-58.6	-36	174.2	60.7	0	0	0	0	111.2	V313 K314 S321	V313-S317 WeakPolarHBondContact O-CA 3.43Å; V313-S317 WeakPolarHBondContact O-CB 3.41Å; V313-S317 PolarHBondContact O-N 3.18Å; V313-S317 PolarHBondContact O-OG 3.45Å; K314-S317 PolarHBondContact O-OG 3.47Å; S317-S321 WeakPolarHBondContact O-CB 3.45Å; S317-S321 PolarHBondContact O-N 3.5Å; S317-S321 PolarHBondContact O-OG 3.35Å
318	Q	59	Low	63.8	Low	30 Å²	30	73.3 Å²	73.3	14%	0.14	38%	0.377	C	S	.	.	H	α-helix	trans	-67	-47.2	178.3	-176	-172.8	-40.9	0	0	112.8	K314 W316 S321 F322 P380 Y383	K314-Q318 WeakPolarHBondContact O-CB 3.5Å; K314-Q318 PolarHBondContact O-N 2.84Å; W316-Q318 PolarHBondContact O-N 3.08Å; Q318-S321 PolarHBondContact O-N 3.4Å; Q318-F322 WeakPolarHBondContact O-CB 3.03Å; Q318-F322 PolarHBondContact O-N 3.38Å; Q318-P380 HydrophobicContact CG-CG 4.4Å; Q318-Y383 HydrophobicContact CG-CE2 3.86Å; Q318-Y383 PolarHBondContact NE2-OH 3.02Å
319	H	66.4	Low	63.4	Low	78 Å²	78	71 Å²	71	36%	0.361	35%	0.348	S	S	.	.	H	α-helix	trans	-70	-39.1	179.3	-70.8	78.8	0	0	0	111.9	F315 W316 F322 I323	F315-H319 AromaticContact CD2-CE1 3.85Å; F315-H319 AromaticContact CE1-CE1 3.97Å; F315-H319 AromaticContact CE2-CE1 3.37Å; F315-H319 WeakPolarHBondContact CE2-CE1 3.23Å; F315-H319 AromaticContact CZ-CE1 3.43Å; F315-H319 VanDerWaalsContact CZ-CE1 3.43Å; F315-H319 WeakPolarHBondContact CZ-CE1 3.36Å; F315-H319 AromaticContact CZ-ND1 3.95Å; F315-H319 AromaticContact CZ-NE2 3.96Å; F315-H319 PolarHBondContact O-N 3.27Å; F315-H319 PolarHBondContact O-ND1 3.29Å; W316-H319 PolarHBondContact O-N 3.37Å; H319-F322 PolarHBondContact O-N 3.11Å; H319-I323 VanDerWaalsContact O-CG1 3.31Å; H319-I323 WeakPolarHBondContact O-CG1 3.38Å; H319-I323 PolarHBondContact O-N 3.45Å
320	I	66.5	Low	62.9	Low	64 Å²	64	71 Å²	71	33%	0.328	35%	0.353	S	S	.	.	H	α-helix	trans	-66.2	-44.2	175.8	-67.5	168.1	0	0	0	110.1	I300 W316 F322 I323 L324	I300-I320 HydrophobicContact CD1-CB 4.3Å; I300-I320 HydrophobicContact CD1-CD1 4.21Å; I300-I320 HydrophobicContact CD1-CG2 3.95Å; W316-I320 HydrophobicContact CB-CD1 4.44Å; W316-I320 WeakPolarHBondContact O-CB 3.23Å; W316-I320 WeakPolarHBondContact O-CG1 3.32Å; W316-I320 PolarHBondContact O-N 3.11Å; I320-F322 VanDerWaalsContact C-N 3.32Å; I320-F322 PolarHBondContact O-N 2.92Å; I320-I323 PolarHBondContact O-N 3.32Å; I320-L324 WeakPolarHBondContact O-CB 3.36Å; I320-L324 PolarHBondContact O-N 2.94Å
321	S	61.4	Low	62.9	Low	5 Å²	5	65.6 Å²	65.6	4%	0.035	33%	0.334	C	S	.	.	H	α-helix	trans	-62.2	-41.1	175.6	-63.1	0	0	0	0	111	S317 Q318 L324 V325	S317-S321 WeakPolarHBondContact O-CB 3.45Å; S317-S321 PolarHBondContact O-N 3.5Å; S317-S321 PolarHBondContact O-OG 3.35Å; Q318-S321 PolarHBondContact O-N 3.4Å; S321-L324 PolarHBondContact O-N 3.39Å; S321-V325 WeakPolarHBondContact O-CB 3.38Å; S321-V325 WeakPolarHBondContact O-CG2 3.39Å; S321-V325 PolarHBondContact O-N 2.99Å
322	F	63.9	Low	62.9	Low	48 Å²	48	62.7 Å²	62.7	21%	0.211	32%	0.324	C	S	.	.	H	α-helix	trans	-60.1	-50.1	174.7	173.2	-117	0	0	0	112.8	I59 I62 L63 Q318 H319 I320 L324 V325 G326	I59-F322 HydrophobicContact CG1-CE2 4.27Å; I59-F322 HydrophobicContact CG1-CZ 4.5Å; I59-F322 HydrophobicContact CG2-CZ 4.2Å; I62-F322 HydrophobicContact CB-CD2 3.81Å; I62-F322 HydrophobicContact CB-CE2 3.88Å; I62-F322 HydrophobicContact CD1-CD2 3.39Å; I62-F322 HydrophobicContact CD1-CE2 3.83Å; I62-F322 HydrophobicContact CD1-CG 4.48Å; I62-F322 HydrophobicContact CG1-CD2 4.17Å; I62-F322 HydrophobicContact CG1-CE2 4.46Å; I62-F322 HydrophobicContact CG2-CB 4.02Å; I62-F322 HydrophobicContact CG2-CD1 4.47Å; I62-F322 HydrophobicContact CG2-CD2 3.38Å; I62-F322 HydrophobicContact CG2-CE2 3.84Å; I62-F322 HydrophobicContact CG2-CG 3.7Å; L63-F322 HydrophobicContact CD1-CZ 4.5Å; L63-F322 HydrophobicContact CD2-CE1 4.01Å; L63-F322 HydrophobicContact CD2-CZ 4.07Å; L63-F322 HydrophobicContact CG-CZ 4.11Å; Q318-F322 WeakPolarHBondContact O-CB 3.03Å; Q318-F322 PolarHBondContact O-N 3.38Å; H319-F322 PolarHBondContact O-N 3.11Å; I320-F322 VanDerWaalsContact C-N 3.32Å; I320-F322 PolarHBondContact O-N 2.92Å; F322-L324 VanDerWaalsContact C-N 3.33Å; F322-L324 PolarHBondContact O-N 3.19Å; F322-V325 PolarHBondContact O-N 2.86Å; F322-G326 PolarHBondContact O-N 3.29Å
323	I	66.4	Low	62.6	Low	103 Å²	103	59.5 Å²	59.5	53%	0.528	31%	0.306	S	S	.	.	H	α-helix	trans	-62.3	-44.5	178.9	-69.5	168.3	0	0	0	110.3	H319 I320 G326 I327	H319-I323 VanDerWaalsContact O-CG1 3.31Å; H319-I323 WeakPolarHBondContact O-CG1 3.38Å; H319-I323 PolarHBondContact O-N 3.45Å; I320-I323 PolarHBondContact O-N 3.32Å; I323-G326 PolarHBondContact O-N 3.4Å; I323-I327 HydrophobicContact CG2-CD1 3.78Å; I323-I327 HydrophobicContact CG2-CG1 4.44Å; I323-I327 VanDerWaalsContact O-CG1 3.29Å; I323-I327 WeakPolarHBondContact O-CG1 3.31Å; I323-I327 PolarHBondContact O-N 3.4Å
324	L	61.3	Low	62.6	Low	64 Å²	64	66.1 Å²	66.1	34%	0.335	33%	0.327	S	S	.	.	H	α-helix	trans	-64.6	-42.9	-180	-173.6	127.5	0	0	0	111.4	V296 I320 S321 F322 I327 I328	V296-L324 HydrophobicContact CG1-CD1 4.2Å; V296-L324 HydrophobicContact CG2-CD1 4.21Å; V296-L324 HydrophobicContact CG2-CD2 3.93Å; I320-L324 WeakPolarHBondContact O-CB 3.36Å; I320-L324 PolarHBondContact O-N 2.94Å; S321-L324 PolarHBondContact O-N 3.39Å; F322-L324 VanDerWaalsContact C-N 3.33Å; F322-L324 PolarHBondContact O-N 3.19Å; L324-I327 PolarHBondContact O-N 3.34Å; L324-I328 HydrophobicContact CD2-CD1 3.52Å; L324-I328 HydrophobicContact CG-CD1 4.14Å; L324-I328 WeakPolarHBondContact O-CB 3.47Å; L324-I328 WeakPolarHBondContact O-CG1 3.37Å; L324-I328 PolarHBondContact O-N 3.24Å
325	V	58.3	Low	62.8	Low	6 Å²	6	61.5 Å²	61.5	4%	0.036	32%	0.316	C	S	.	.	H	α-helix	trans	-60.7	-45.4	173.7	164.7	0	0	0	0	111	S321 F322 I328 I329 I375	S321-V325 WeakPolarHBondContact O-CB 3.38Å; S321-V325 WeakPolarHBondContact O-CG2 3.39Å; S321-V325 PolarHBondContact O-N 2.99Å; F322-V325 PolarHBondContact O-N 2.86Å; V325-I328 PolarHBondContact O-N 2.84Å; V325-I329 HydrophobicContact CG1-CD1 3.94Å; V325-I329 VanDerWaalsContact O-CG1 3.27Å; V325-I329 WeakPolarHBondContact O-CG1 3.45Å; V325-I329 PolarHBondContact O-N 3.33Å; V325-I375 HydrophobicContact CG1-CD1 3.19Å; V325-I375 HydrophobicContact CG1-CG1 3.49Å; V325-I375 VanDerWaalsContact CG1-CG1 3.49Å; V325-I375 HydrophobicContact CG2-CG1 4.38Å
326	G	60.8	Low	62.7	Low	28 Å²	28	57 Å²	57	29%	0.289	30%	0.297	S	S	.	.	H	α-helix	trans	-61.7	-43.3	175.7	0	0	0	0	0	113	F322 I323 I329 V330	F322-G326 PolarHBondContact O-N 3.29Å; I323-G326 PolarHBondContact O-N 3.4Å; G326-I329 PolarHBondContact O-N 3.46Å; G326-V330 WeakPolarHBondContact O-CG2 3.14Å; G326-V330 PolarHBondContact O-N 2.89Å
327	I	62	Low	62.5	Low	100 Å²	100	52.5 Å²	52.5	51%	0.513	28%	0.281	S	S	.	.	H	α-helix	trans	-63.2	-44.6	174.7	-69.3	168.1	0	0	0	110.5	I323 L324 I329 V330 T331	I323-I327 HydrophobicContact CG2-CD1 3.78Å; I323-I327 HydrophobicContact CG2-CG1 4.44Å; I323-I327 VanDerWaalsContact O-CG1 3.29Å; I323-I327 WeakPolarHBondContact O-CG1 3.31Å; I323-I327 PolarHBondContact O-N 3.4Å; L324-I327 PolarHBondContact O-N 3.34Å; I327-I329 VanDerWaalsContact C-N 3.32Å; I327-I329 PolarHBondContact O-N 2.87Å; I327-V330 PolarHBondContact O-N 3.42Å; I327-T331 HydrophobicContact CG2-CG2 4.13Å; I327-T331 WeakPolarHBondContact O-CB 3.29Å; I327-T331 VanDerWaalsContact O-CG2 3.27Å; I327-T331 WeakPolarHBondContact O-CG2 2.8Å; I327-T331 PolarHBondContact O-N 3.45Å; I327-T331 PolarHBondContact O-OG1 3.21Å
328	I	60.4	Low	62.8	Low	83 Å²	83	55.6 Å²	55.6	43%	0.426	30%	0.296	S	S	.	.	H	α-helix	trans	-57.8	-47.3	176.2	-72.5	166.5	0	0	0	109.7	L324 V325 T331 S332	L324-I328 HydrophobicContact CD2-CD1 3.52Å; L324-I328 HydrophobicContact CG-CD1 4.14Å; L324-I328 WeakPolarHBondContact O-CB 3.47Å; L324-I328 WeakPolarHBondContact O-CG1 3.37Å; L324-I328 PolarHBondContact O-N 3.24Å; V325-I328 PolarHBondContact O-N 2.84Å; I328-T331 PolarHBondContact O-OG1 2.84Å; I328-T331 VanDerWaalsContact O-OG1 3.08Å; I328-S332 WeakPolarHBondContact O-CB 3.36Å; I328-S332 PolarHBondContact O-N 3.26Å; I328-S332 PolarHBondContact O-OG 3.01Å
329	I	57.8	Low	63.1	Low	16 Å²	16	57.6 Å²	57.6	8%	0.082	31%	0.31	C	S	.	.	H	α-helix	trans	-60.7	-52.1	178.5	-68.7	162.5	0	0	0	111.5	F55 V325 G326 I327 T331 S332 I333 I375	F55-I329 HydrophobicContact CB-CG2 4.44Å; F55-I329 HydrophobicContact CD1-CB 4.46Å; F55-I329 HydrophobicContact CD1-CD1 3.56Å; F55-I329 HydrophobicContact CD1-CG1 3.91Å; F55-I329 HydrophobicContact CD1-CG2 3.65Å; F55-I329 HydrophobicContact CD2-CG2 3.66Å; F55-I329 HydrophobicContact CE1-CB 4.33Å; F55-I329 HydrophobicContact CE1-CD1 3.82Å; F55-I329 HydrophobicContact CE1-CG1 3.67Å; F55-I329 HydrophobicContact CE1-CG2 3.67Å; F55-I329 HydrophobicContact CE2-CG2 3.58Å; F55-I329 HydrophobicContact CG-CD1 4.41Å; F55-I329 HydrophobicContact CG-CG2 3.68Å; F55-I329 HydrophobicContact CZ-CG1 4.25Å; F55-I329 HydrophobicContact CZ-CG2 3.63Å; V325-I329 HydrophobicContact CG1-CD1 3.94Å; V325-I329 VanDerWaalsContact O-CG1 3.27Å; V325-I329 WeakPolarHBondContact O-CG1 3.45Å; V325-I329 PolarHBondContact O-N 3.33Å; G326-I329 PolarHBondContact O-N 3.46Å; I327-I329 VanDerWaalsContact C-N 3.32Å; I327-I329 PolarHBondContact O-N 2.87Å; I329-T331 VanDerWaalsContact C-N 3.35Å; I329-T331 PolarHBondContact O-N 3.44Å; I329-S332 PolarHBondContact O-N 3.41Å; I329-S332 PolarHBondContact O-OG 2.91Å; I329-I333 HydrophobicContact CG2-CD1 3.62Å; I329-I333 HydrophobicContact CG2-CG1 4.28Å; I329-I333 WeakPolarHBondContact O-CG1 3.09Å; I329-I333 PolarHBondContact O-N 3.48Å; I329-I375 HydrophobicContact CD1-CD1 3.28Å; I329-I375 HydrophobicContact CG1-CD1 3.64Å
330	V	61.6	Low	63	Low	98 Å²	98	54.8 Å²	54.8	59%	0.594	30%	0.298	S	S	*	.	H	α-helix	trans	-64.7	-41.5	-175.7	172.2	0	0	0	0	111.3	G326 I327 R334	G326-V330 WeakPolarHBondContact O-CG2 3.14Å; G326-V330 PolarHBondContact O-N 2.89Å; I327-V330 PolarHBondContact O-N 3.42Å; V330-R334 VanDerWaalsContact O-CB 3.26Å; V330-R334 WeakPolarHBondContact O-CB 3.28Å; V330-R334 PolarHBondContact O-N 3.28Å
331	T	61.3	Low	62.9	Low	86 Å²	86	52.5 Å²	52.5	53%	0.528	29%	0.287	S	S	.	.	H	α-helix	trans	-68.5	-36.1	177.7	54.9	0	0	0	0	112	I327 I328 I329 G335	I327-T331 HydrophobicContact CG2-CG2 4.13Å; I327-T331 WeakPolarHBondContact O-CB 3.29Å; I327-T331 VanDerWaalsContact O-CG2 3.27Å; I327-T331 WeakPolarHBondContact O-CG2 2.8Å; I327-T331 PolarHBondContact O-N 3.45Å; I327-T331 PolarHBondContact O-OG1 3.21Å; I328-T331 PolarHBondContact O-OG1 2.84Å; I328-T331 VanDerWaalsContact O-OG1 3.08Å; I329-T331 VanDerWaalsContact C-N 3.35Å; I329-T331 PolarHBondContact O-N 3.44Å; T331-G335 PolarHBondContact O-N 2.94Å
332	S	61.9	Low	63	Low	21 Å²	21	59.3 Å²	59.3	15%	0.147	32%	0.316	C	S	.	.	H	α-helix	trans	-71.2	-43.4	-180	83	0	0	0	0	112.4	I328 I329 G335 L336 Y367	I328-S332 WeakPolarHBondContact O-CB 3.36Å; I328-S332 PolarHBondContact O-N 3.26Å; I328-S332 PolarHBondContact O-OG 3.01Å; I329-S332 PolarHBondContact O-N 3.41Å; I329-S332 PolarHBondContact O-OG 2.91Å; S332-G335 PolarHBondContact O-N 2.91Å; S332-L336 VanDerWaalsContact O-CB 3.31Å; S332-L336 WeakPolarHBondContact O-CB 3.45Å; S332-L336 PolarHBondContact O-N 2.82Å; S332-Y367 WeakPolarHBondContact CB-OH 3.32Å
333	I	62	Low	63	Low	27 Å²	27	62.7 Å²	62.7	14%	0.138	33%	0.331	C	S	.	.	H	α-helix	trans	-61.4	-50.3	172.9	-63.8	168.4	0	0	0	110.4	F55 I329 G335 L336 L337 F368	F55-I333 HydrophobicContact CD2-CD1 3.74Å; F55-I333 HydrophobicContact CE2-CD1 3.5Å; F55-I333 VanDerWaalsContact CE2-CD1 3.5Å; F55-I333 HydrophobicContact CE2-CG1 3.93Å; I329-I333 HydrophobicContact CG2-CD1 3.62Å; I329-I333 HydrophobicContact CG2-CG1 4.28Å; I329-I333 WeakPolarHBondContact O-CG1 3.09Å; I329-I333 PolarHBondContact O-N 3.48Å; I333-G335 VanDerWaalsContact C-N 3.33Å; I333-G335 PolarHBondContact O-N 2.87Å; I333-L336 PolarHBondContact O-N 2.63Å; I333-L337 HydrophobicContact CG2-CD1 3.78Å; I333-L337 HydrophobicContact CG2-CG 4.25Å; I333-L337 WeakPolarHBondContact O-CB 3.4Å; I333-L337 WeakPolarHBondContact O-CG 3.17Å; I333-L337 PolarHBondContact O-N 2.85Å; I333-F368 HydrophobicContact CB-CZ 4.16Å; I333-F368 HydrophobicContact CD1-CE1 3.62Å; I333-F368 HydrophobicContact CD1-CZ 3.79Å; I333-F368 HydrophobicContact CG1-CE1 3.75Å; I333-F368 HydrophobicContact CG1-CE2 4.13Å; I333-F368 HydrophobicContact CG1-CZ 3.5Å; I333-F368 VanDerWaalsContact CG1-CZ 3.5Å; I333-F368 HydrophobicContact CG2-CE2 4.32Å; I333-F368 HydrophobicContact CG2-CZ 3.67Å
334	R	65.5	Low	62.7	Low	175 Å²	175	58 Å²	58	66%	0.66	31%	0.306	S	S	*	.	H	α-helix	trans	-61.5	-43.9	-179.5	-179.5	178.6	172.9	175.1	-0.3	111	V330 L337 I338	V330-R334 VanDerWaalsContact O-CB 3.26Å; V330-R334 WeakPolarHBondContact O-CB 3.28Å; V330-R334 PolarHBondContact O-N 3.28Å; R334-L337 PolarHBondContact O-N 3.23Å; R334-I338 HydrophobicContact CG-CD1 3.73Å; R334-I338 HydrophobicContact CG-CG1 4.46Å; R334-I338 WeakPolarHBondContact O-CB 3.27Å; R334-I338 VanDerWaalsContact O-CG1 3.24Å; R334-I338 WeakPolarHBondContact O-CG1 3.42Å; R334-I338 PolarHBondContact O-N 3.05Å
335	G	65.1	Low	62.8	Low	32 Å²	32	60.2 Å²	60.2	33%	0.33	31%	0.311	S	S	.	.	H	α-helix	trans	-60.6	-46.2	177.1	0	0	0	0	0	112.1	T331 S332 I333 T339	T331-G335 PolarHBondContact O-N 2.94Å; S332-G335 PolarHBondContact O-N 2.91Å; I333-G335 VanDerWaalsContact C-N 3.33Å; I333-G335 PolarHBondContact O-N 2.87Å; G335-T339 WeakPolarHBondContact O-CB 3.31Å; G335-T339 PolarHBondContact O-N 3.21Å; G335-T339 PolarHBondContact O-OG1 3.27Å
336	L	65.7	Low	62.8	Low	5 Å²	5	64 Å²	64	3%	0.026	34%	0.343	C	S	.	.	H	α-helix	trans	-61.7	-50.3	176.3	177.2	141.1	0	0	0	111.8	L138 S332 I333 I338 T339 L340 M364 Y367	L138-L336 HydrophobicContact CD1-CD1 4.37Å; S332-L336 VanDerWaalsContact O-CB 3.31Å; S332-L336 WeakPolarHBondContact O-CB 3.45Å; S332-L336 PolarHBondContact O-N 2.82Å; I333-L336 PolarHBondContact O-N 2.63Å; L336-I338 PolarHBondContact O-N 2.84Å; L336-T339 PolarHBondContact O-N 3.29Å; L336-L340 HydrophobicContact CD1-CD1 4.23Å; L336-L340 HydrophobicContact CD2-CD1 3.35Å; L336-L340 HydrophobicContact CD2-CG 4.43Å; L336-L340 HydrophobicContact CG-CD1 3.55Å; L336-L340 HydrophobicContact CG-CG 4.27Å; L336-L340 WeakPolarHBondContact O-CB 3.16Å; L336-L340 VanDerWaalsContact O-CG 3.28Å; L336-L340 WeakPolarHBondContact O-CG 3.42Å; L336-L340 PolarHBondContact O-N 2.62Å; L336-M364 HydrophobicContact CD2-CB 4.27Å; L336-M364 HydrophobicContact CD2-CG 4.09Å; L336-Y367 HydrophobicContact CD1-CD1 3.54Å; L336-Y367 HydrophobicContact CD1-CD2 3.4Å; L336-Y367 HydrophobicContact CD1-CE1 4.02Å; L336-Y367 HydrophobicContact CD1-CE2 3.86Å; L336-Y367 HydrophobicContact CD1-CG 3.2Å
337	L	63.9	Low	62.5	Low	21 Å²	21	66.7 Å²	66.7	11%	0.11	35%	0.35	C	S	.	.	H	α-helix	trans	-59.9	-45.2	-179.1	-72.5	175.2	0	0	0	111.4	F24 F48 I333 R334 L340 T341 M364	F24-L337 HydrophobicContact CE1-CD2 4Å; F24-L337 HydrophobicContact CZ-CB 4.29Å; F24-L337 HydrophobicContact CZ-CD1 4.4Å; F24-L337 HydrophobicContact CZ-CD2 4.15Å; F48-L337 HydrophobicContact CE2-CD1 4.36Å; I333-L337 HydrophobicContact CG2-CD1 3.78Å; I333-L337 HydrophobicContact CG2-CG 4.25Å; I333-L337 WeakPolarHBondContact O-CB 3.4Å; I333-L337 WeakPolarHBondContact O-CG 3.17Å; I333-L337 PolarHBondContact O-N 2.85Å; R334-L337 PolarHBondContact O-N 3.23Å; L337-L340 PolarHBondContact O-N 2.9Å; L337-T341 WeakPolarHBondContact O-CB 3.41Å; L337-T341 PolarHBondContact O-N 3.44Å; L337-T341 PolarHBondContact O-OG1 3.47Å; L337-M364 HydrophobicContact CD2-SD 4.12Å
338	I	67	Low	62	Low	77 Å²	77	63 Å²	63	40%	0.395	33%	0.333	S	S	.	.	H	α-helix	trans	-63.9	-44.9	178.6	-68.3	168.8	0	0	0	111.4	R334 L336 L340 T341 K342	R334-I338 HydrophobicContact CG-CD1 3.73Å; R334-I338 HydrophobicContact CG-CG1 4.46Å; R334-I338 WeakPolarHBondContact O-CB 3.27Å; R334-I338 VanDerWaalsContact O-CG1 3.24Å; R334-I338 WeakPolarHBondContact O-CG1 3.42Å; R334-I338 PolarHBondContact O-N 3.05Å; L336-I338 PolarHBondContact O-N 2.84Å; I338-L340 VanDerWaalsContact C-N 3.35Å; I338-T341 PolarHBondContact O-N 3.36Å; I338-K342 HydrophobicContact CG2-CD 4.46Å; I338-K342 WeakPolarHBondContact O-CG 3.2Å; I338-K342 PolarHBondContact O-N 2.89Å
339	T	65.4	Low	61.7	Low	72 Å²	72	62.1 Å²	62.1	44%	0.442	33%	0.334	S	S	.	.	H	α-helix	trans	-64.3	-43.9	-178.4	-53.8	0	0	0	0	110.6	L138 G335 L336 K342 F343	L138-T339 HydrophobicContact CD2-CG2 4.38Å; G335-T339 WeakPolarHBondContact O-CB 3.31Å; G335-T339 PolarHBondContact O-N 3.21Å; G335-T339 PolarHBondContact O-OG1 3.27Å; L336-T339 PolarHBondContact O-N 3.29Å; T339-K342 PolarHBondContact O-N 2.8Å; T339-F343 WeakPolarHBondContact O-CB 3.4Å; T339-F343 PolarHBondContact O-N 3.03Å
340	L	64	Low	61.5	Low	20 Å²	20	64.9 Å²	64.9	11%	0.105	36%	0.355	C	S	.	.	H	α-helix	trans	-70.3	-36	178.8	-68.8	173.6	0	0	0	112.8	L336 L337 I338 F343 F344 L360 I363	L336-L340 HydrophobicContact CD1-CD1 4.23Å; L336-L340 HydrophobicContact CD2-CD1 3.35Å; L336-L340 HydrophobicContact CD2-CG 4.43Å; L336-L340 HydrophobicContact CG-CD1 3.55Å; L336-L340 HydrophobicContact CG-CG 4.27Å; L336-L340 WeakPolarHBondContact O-CB 3.16Å; L336-L340 VanDerWaalsContact O-CG 3.28Å; L336-L340 WeakPolarHBondContact O-CG 3.42Å; L336-L340 PolarHBondContact O-N 2.62Å; L337-L340 PolarHBondContact O-N 2.9Å; I338-L340 VanDerWaalsContact C-N 3.35Å; L340-F343 PolarHBondContact O-N 2.92Å; L340-F344 WeakPolarHBondContact O-CB 3.3Å; L340-F344 PolarHBondContact O-N 2.75Å; L340-L360 HydrophobicContact CB-CD1 3.31Å; L340-L360 HydrophobicContact CD1-CD1 3.42Å; L340-L360 VanDerWaalsContact CD1-CD1 3.42Å; L340-L360 HydrophobicContact CD2-CD1 4.1Å; L340-L360 HydrophobicContact CG-CD1 3.77Å; L340-I363 HydrophobicContact CD1-CG2 3.94Å; L340-I363 HydrophobicContact CD2-CG2 4.16Å
341	T	64.7	Low	61	Low	15 Å²	15	68.1 Å²	68.1	9%	0.092	36%	0.361	C	S	.	.	H	α-helix	trans	-62.5	-41.9	172.3	-61.9	0	0	0	0	111.4	Q28 L337 I338 F344 Y345	Q28-T341 HydrophobicContact CG-CG2 4.47Å; L337-T341 WeakPolarHBondContact O-CB 3.41Å; L337-T341 PolarHBondContact O-N 3.44Å; L337-T341 PolarHBondContact O-OG1 3.47Å; I338-T341 PolarHBondContact O-N 3.36Å; T341-F344 WeakPolarHBondContact O-CB 3.49Å; T341-F344 PolarHBondContact O-N 2.98Å; T341-Y345 HydrophobicContact CG2-CD2 3.83Å; T341-Y345 HydrophobicContact CG2-CE2 3.66Å; T341-Y345 VanDerWaalsContact O-CD2 3.24Å; T341-Y345 WeakPolarHBondContact O-CD2 3.37Å; T341-Y345 PolarHBondContact O-N 3.03Å
342	K	64.3	Low	60.8	Low	149 Å²	149	66 Å²	66	65%	0.648	35%	0.35	S	S	*	.	H	α-helix	trans	-64	-43.6	175.5	-73.1	179.9	178.4	-175.1	0	112.3	I338 T339 F344 Y345 A346	I338-K342 HydrophobicContact CG2-CD 4.46Å; I338-K342 WeakPolarHBondContact O-CG 3.2Å; I338-K342 PolarHBondContact O-N 2.89Å; T339-K342 PolarHBondContact O-N 2.8Å; K342-F344 VanDerWaalsContact C-N 3.31Å; K342-F344 PolarHBondContact O-N 2.98Å; K342-Y345 PolarHBondContact O-N 3.31Å; K342-A346 PolarHBondContact O-N 2.78Å; K342-A346 VanDerWaalsContact O-N 3.09Å
343	F	62.8	Low	61	Low	119 Å²	119	65.1 Å²	65.1	52%	0.522	34%	0.343	S	S	.	.	H	α-helix	trans	-61.2	-41.2	175.1	-178.5	-97.2	0	0	0	111.7	T339 L340 A346 I347	T339-F343 WeakPolarHBondContact O-CB 3.4Å; T339-F343 PolarHBondContact O-N 3.03Å; L340-F343 PolarHBondContact O-N 2.92Å; F343-A346 PolarHBondContact O-N 2.93Å; F343-I347 HydrophobicContact CD1-CD1 3.89Å; F343-I347 HydrophobicContact CD2-CD1 3.66Å; F343-I347 HydrophobicContact CE1-CD1 3.41Å; F343-I347 VanDerWaalsContact CE1-CD1 3.41Å; F343-I347 HydrophobicContact CE2-CD1 3.16Å; F343-I347 HydrophobicContact CG-CD1 4.01Å; F343-I347 HydrophobicContact CZ-CD1 3.04Å; F343-I347 PolarHBondContact O-N 3.04Å; F343-I347 VanDerWaalsContact O-N 3.14Å
344	F	61.7	Low	61.6	Low	3 Å²	3	64.6 Å²	64.6	1%	0.013	34%	0.341	C	S	.	.	H	α-helix	trans	-58.3	-53	173.7	175.9	-97.1	0	0	0	110.9	L29 Y33 L340 T341 K342 A346 I347 S348 I356 V357	L29-F344 HydrophobicContact CD1-CD1 4.48Å; L29-F344 HydrophobicContact CD1-CG 4.48Å; L29-F344 WeakPolarHBondContact O-CE1 3.23Å; Y33-F344 HydrophobicContact CD2-CE1 4.16Å; Y33-F344 AromaticContact CD2-CZ 3.99Å; Y33-F344 HydrophobicContact CD2-CZ 3.99Å; Y33-F344 AromaticContact CE2-CE1 3.74Å; Y33-F344 HydrophobicContact CE2-CE1 3.74Å; Y33-F344 AromaticContact CE2-CZ 3.7Å; Y33-F344 HydrophobicContact CE2-CZ 3.7Å; L340-F344 WeakPolarHBondContact O-CB 3.3Å; L340-F344 PolarHBondContact O-N 2.75Å; T341-F344 WeakPolarHBondContact O-CB 3.49Å; T341-F344 PolarHBondContact O-N 2.98Å; K342-F344 VanDerWaalsContact C-N 3.31Å; K342-F344 PolarHBondContact O-N 2.98Å; F344-A346 PolarHBondContact O-N 3.17Å; F344-I347 PolarHBondContact O-N 2.92Å; F344-I347 VanDerWaalsContact O-N 3.11Å; F344-S348 WeakPolarHBondContact O-CA 3.47Å; F344-S348 WeakPolarHBondContact O-CB 3.28Å; F344-S348 PolarHBondContact O-N 3.03Å; F344-S348 PolarHBondContact O-OG 2.97Å; F344-S348 VanDerWaalsContact O-OG 3.09Å; F344-I356 HydrophobicContact CD2-CB 4.29Å; F344-I356 HydrophobicContact CD2-CG2 3.59Å; F344-I356 HydrophobicContact CE2-CB 4.35Å; F344-I356 HydrophobicContact CE2-CG2 4.14Å; F344-V357 HydrophobicContact CE2-CG2 3.86Å; F344-V357 HydrophobicContact CZ-CG2 4.48Å
345	Y	63.4	Low	61.9	Low	111 Å²	111	57 Å²	57	44%	0.435	31%	0.314	S	S	.	.	H	α-helix	trans	-56.7	-36.3	178.4	-85.4	-68.8	0	0	0	113	T341 K342	T341-Y345 HydrophobicContact CG2-CD2 3.83Å; T341-Y345 HydrophobicContact CG2-CE2 3.66Å; T341-Y345 VanDerWaalsContact O-CD2 3.24Å; T341-Y345 WeakPolarHBondContact O-CD2 3.37Å; T341-Y345 PolarHBondContact O-N 3.03Å; K342-Y345 PolarHBondContact O-N 3.31Å
346	A	58	Low	62.2	Low	86 Å²	86	56.6 Å²	56.6	71%	0.711	30%	0.304	S	S	*	.	H	α-helix	trans	-71.4	-30	179.3	0	0	0	0	0	114.3	K342 F343 F344	K342-A346 PolarHBondContact O-N 2.78Å; K342-A346 VanDerWaalsContact O-N 3.09Å; F343-A346 PolarHBondContact O-N 2.93Å; F344-A346 PolarHBondContact O-N 3.17Å
347	I	53.9	Low	62.8	Low	84 Å²	84	56.3 Å²	56.3	43%	0.431	30%	0.303	S	S	.	.	H	α-helix	trans	-110.1	-14.6	-172.4	-70.6	162.3	0	0	0	112.6	F343 F344 S349 I356	F343-I347 HydrophobicContact CD1-CD1 3.89Å; F343-I347 HydrophobicContact CD2-CD1 3.66Å; F343-I347 HydrophobicContact CE1-CD1 3.41Å; F343-I347 VanDerWaalsContact CE1-CD1 3.41Å; F343-I347 HydrophobicContact CE2-CD1 3.16Å; F343-I347 HydrophobicContact CG-CD1 4.01Å; F343-I347 HydrophobicContact CZ-CD1 3.04Å; F343-I347 PolarHBondContact O-N 3.04Å; F343-I347 VanDerWaalsContact O-N 3.14Å; F344-I347 PolarHBondContact O-N 2.92Å; F344-I347 VanDerWaalsContact O-N 3.11Å; I347-S349 PolarHBondContact O-N 2.96Å; I347-I356 HydrophobicContact CG2-CD1 4.08Å
348	S	51.7	Low	63.6	Low	24 Å²	24	55.3 Å²	55.3	17%	0.168	30%	0.298	C	S	.	.			trans	-66	119.6	-172	65.6	0	0	0	0	111.2	Y33 F344	Y33-S348 WeakPolarHBondContact OH-CB 3.25Å; Y33-S348 PolarHBondContact OH-O 3.23Å; Y33-S348 VanDerWaalsContact OH-O 3.05Å; Y33-S348 PolarHBondContact OH-OG 3.05Å; F344-S348 WeakPolarHBondContact O-CA 3.47Å; F344-S348 WeakPolarHBondContact O-CB 3.28Å; F344-S348 PolarHBondContact O-N 3.03Å; F344-S348 PolarHBondContact O-OG 2.97Å; F344-S348 VanDerWaalsContact O-OG 3.09Å
349	S	54.6	Low	64.1	Low	63 Å²	63	55.4 Å²	55.4	44%	0.441	30%	0.298	S	S	.	.			trans	-115.4	148.3	165.3	178.1	0	0	0	0	107.6	I347 K351 S352 S353	I347-S349 PolarHBondContact O-N 2.96Å; S349-K351 PolarHBondContact O-N 3.16Å; S349-S352 PolarHBondContact O-N 2.9Å; S349-S352 VanDerWaalsContact O-N 3.15Å; S349-S352 PolarHBondContact O-OG 3.36Å; S349-S353 PolarHBondContact O-N 2.86Å
350	S	54.2	Low	64.7	Low	75 Å²	75	52.6 Å²	52.6	52%	0.524	28%	0.281	S	S	.	.	T	Hydrogen-bonded Turn	trans	-58.4	-21.6	-175.2	58	0	0	0	0	114.7
351	K	50.6	Low	65.7	Low	166 Å²	166	51.7 Å²	51.7	72%	0.722	28%	0.276	S	S	*	.	T	Hydrogen-bonded Turn	trans	-91.8	-23.1	179.9	-60.4	-155.1	179.2	-173.9	0	115	S349	S349-K351 PolarHBondContact O-N 3.16Å
352	S	57.3	Low	66.6	Low	41 Å²	41	52 Å²	52	29%	0.287	28%	0.276	S	S	.	.	T	Hydrogen-bonded Turn	trans	-105.6	-4.5	-177.9	57.5	0	0	0	0	113.8	S349 N354 V355 I356	S349-S352 PolarHBondContact O-N 2.9Å; S349-S352 VanDerWaalsContact O-N 3.15Å; S349-S352 PolarHBondContact O-OG 3.36Å; S352-N354 VanDerWaalsContact C-N 3.29Å; S352-N354 PolarHBondContact O-N 2.66Å; S352-V355 PolarHBondContact O-N 3.27Å; S352-I356 WeakPolarHBondContact O-CG1 3.42Å; S352-I356 PolarHBondContact O-N 2.94Å; S352-I356 WeakPolarHBondContact OG-CD1 3.29Å
353	S	66.2	Low	67.3	Low	2 Å²	2	47 Å²	47	1%	0.014	26%	0.256	C	S	.	.	H	α-helix	trans	-49.6	-45	-175.5	60.3	0	0	0	0	113.3	S349 V355 I356 V357	S349-S353 PolarHBondContact O-N 2.86Å; S353-V355 PolarHBondContact O-N 2.91Å; S353-I356 PolarHBondContact O-N 3.49Å; S353-V357 WeakPolarHBondContact O-CB 3.38Å; S353-V357 WeakPolarHBondContact O-CG2 3.1Å; S353-V357 PolarHBondContact O-N 3.36Å
354	N	73.1	Confident	68.2	Low	17 Å²	17	41.4 Å²	41.4	9%	0.091	23%	0.231	C	C	.	.	H	α-helix	trans	-62.2	-41.7	179.1	-67.5	-34.8	0	0	0	113.3	Q37 V40 F97 S352 V357 L358	Q37-N354 PolarHBondContact OE1-ND2 3.17Å; V40-N354 HydrophobicContact CG2-CB 4.2Å; F97-N354 HydrophobicContact CD1-CB 4.42Å; F97-N354 HydrophobicContact CE1-CB 4.48Å; S352-N354 VanDerWaalsContact C-N 3.29Å; S352-N354 PolarHBondContact O-N 2.66Å; N354-V357 PolarHBondContact O-N 3.5Å; N354-L358 WeakPolarHBondContact O-CG 3.43Å; N354-L358 PolarHBondContact O-N 2.94Å; N354-L358 VanDerWaalsContact O-N 3.09Å
355	V	73.1	Confident	69.1	Low	16 Å²	16	41.2 Å²	41.2	10%	0.097	23%	0.231	C	C	.	.	H	α-helix	trans	-67.3	-43.9	177.2	177.2	0	0	0	0	110.2	I94 F97 I98 S352 S353 V357 L358 L359	I94-V355 HydrophobicContact CG2-CG1 4.47Å; F97-V355 HydrophobicContact CB-CG2 3.51Å; F97-V355 HydrophobicContact CG-CG2 4.47Å; I98-V355 HydrophobicContact CD1-CG1 4.34Å; I98-V355 HydrophobicContact CG1-CG1 4.08Å; I98-V355 HydrophobicContact CG1-CG2 4.27Å; S352-V355 PolarHBondContact O-N 3.27Å; S353-V355 PolarHBondContact O-N 2.91Å; V355-V357 PolarHBondContact O-N 2.95Å; V355-L358 PolarHBondContact O-N 3.43Å; V355-L359 HydrophobicContact CG1-CD1 4.04Å; V355-L359 HydrophobicContact CG1-CG 4.42Å; V355-L359 WeakPolarHBondContact O-CB 3.28Å; V355-L359 WeakPolarHBondContact O-CG 3.35Å; V355-L359 PolarHBondContact O-N 3.44Å
356	I	71.7	Confident	69.9	Low	22 Å²	22	36.4 Å²	36.4	11%	0.113	21%	0.212	C	C	.	.	H	α-helix	trans	-61.9	-37.4	-179.9	-60	164.6	0	0	0	110.4	F344 I347 S352 S353 L359 L360	F344-I356 HydrophobicContact CD2-CB 4.29Å; F344-I356 HydrophobicContact CD2-CG2 3.59Å; F344-I356 HydrophobicContact CE2-CB 4.35Å; F344-I356 HydrophobicContact CE2-CG2 4.14Å; I347-I356 HydrophobicContact CG2-CD1 4.08Å; S352-I356 WeakPolarHBondContact O-CG1 3.42Å; S352-I356 PolarHBondContact O-N 2.94Å; S352-I356 WeakPolarHBondContact OG-CD1 3.29Å; S353-I356 PolarHBondContact O-N 3.49Å; I356-L359 WeakPolarHBondContact O-CB 3.38Å; I356-L359 PolarHBondContact O-N 3.14Å; I356-L360 WeakPolarHBondContact O-CB 3.4Å; I356-L360 PolarHBondContact O-N 2.61Å
357	V	77.4	Confident	70.9	Confident	0 Å²	0	33.2 Å²	33.2	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-72.9	-35.3	179.8	170	0	0	0	0	112.5	F25 L29 F30 V40 F344 S353 N354 V355 L360 A361	F25-V357 HydrophobicContact CD2-CG1 4.34Å; F25-V357 HydrophobicContact CE2-CG1 3.35Å; F25-V357 HydrophobicContact CZ-CG1 3.98Å; L29-V357 HydrophobicContact CD2-CG1 4.1Å; L29-V357 HydrophobicContact CD2-CG2 3.9Å; F30-V357 HydrophobicContact CD2-CG2 4.47Å; F30-V357 HydrophobicContact CE2-CB 4.25Å; F30-V357 HydrophobicContact CE2-CG1 4.1Å; F30-V357 HydrophobicContact CE2-CG2 3.35Å; F30-V357 HydrophobicContact CZ-CG2 3.67Å; V40-V357 HydrophobicContact CG1-CB 4.01Å; V40-V357 HydrophobicContact CG1-CG1 3.49Å; V40-V357 VanDerWaalsContact CG1-CG1 3.49Å; F344-V357 HydrophobicContact CE2-CG2 3.86Å; F344-V357 HydrophobicContact CZ-CG2 4.48Å; S353-V357 WeakPolarHBondContact O-CB 3.38Å; S353-V357 WeakPolarHBondContact O-CG2 3.1Å; S353-V357 PolarHBondContact O-N 3.36Å; N354-V357 PolarHBondContact O-N 3.5Å; V355-V357 PolarHBondContact O-N 2.95Å; V357-L360 WeakPolarHBondContact O-CB 3.48Å; V357-L360 PolarHBondContact O-N 2.96Å; V357-A361 PolarHBondContact O-N 2.55Å
358	L	81.3	Confident	72	Confident	0 Å²	0	29.2 Å²	29.2	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-69.7	-39.7	171.3	-68.8	168.9	0	0	0	111.5	V40 I43 V90 I94 F97 N354 V355 L360 A361 Q362	V40-L358 HydrophobicContact CG1-CD2 4.08Å; V40-L358 HydrophobicContact CG1-CG 3.99Å; V40-L358 HydrophobicContact CG2-CD1 4.27Å; V40-L358 HydrophobicContact CG2-CD2 4.43Å; V40-L358 HydrophobicContact CG2-CG 4.33Å; I43-L358 HydrophobicContact CB-CD2 4.27Å; I43-L358 HydrophobicContact CD1-CD2 4.15Å; I43-L358 HydrophobicContact CG2-CD2 3.89Å; V90-L358 HydrophobicContact CG1-CB 4.43Å; V90-L358 VanDerWaalsContact CG1-O 3.28Å; V90-L358 WeakPolarHBondContact CG1-O 3.38Å; I94-L358 HydrophobicContact CD1-CB 4.16Å; I94-L358 HydrophobicContact CG1-CB 3.51Å; I94-L358 HydrophobicContact CG1-CD1 4.27Å; F97-L358 HydrophobicContact CD2-CD1 3.47Å; F97-L358 VanDerWaalsContact CD2-CD1 3.47Å; F97-L358 HydrophobicContact CE2-CD1 3.9Å; N354-L358 WeakPolarHBondContact O-CG 3.43Å; N354-L358 PolarHBondContact O-N 2.94Å; N354-L358 VanDerWaalsContact O-N 3.09Å; V355-L358 PolarHBondContact O-N 3.43Å; L358-L360 PolarHBondContact O-N 3.47Å; L358-A361 PolarHBondContact O-N 3.43Å; L358-Q362 WeakPolarHBondContact O-CB 3.38Å; L358-Q362 PolarHBondContact O-N 2.9Å
359	L	77.9	Confident	73.2	Confident	79 Å²	79	28.7 Å²	28.7	41%	0.414	16%	0.157	S	C	.	.	H	α-helix	trans	-60.3	-37	170.7	-73.9	169.9	0	0	0	111.4	I94 V355 I356 Q362 I363	I94-L359 HydrophobicContact CD1-CD2 3.89Å; I94-L359 HydrophobicContact CD1-CG 4.25Å; V355-L359 HydrophobicContact CG1-CD1 4.04Å; V355-L359 HydrophobicContact CG1-CG 4.42Å; V355-L359 WeakPolarHBondContact O-CB 3.28Å; V355-L359 WeakPolarHBondContact O-CG 3.35Å; V355-L359 PolarHBondContact O-N 3.44Å; I356-L359 WeakPolarHBondContact O-CB 3.38Å; I356-L359 PolarHBondContact O-N 3.14Å; L359-Q362 WeakPolarHBondContact O-CB 3.32Å; L359-Q362 PolarHBondContact O-N 3.02Å; L359-I363 WeakPolarHBondContact O-CB 3.32Å; L359-I363 VanDerWaalsContact O-CG1 3.31Å; L359-I363 WeakPolarHBondContact O-CG1 3.39Å; L359-I363 PolarHBondContact O-N 2.93Å
360	L	77.4	Confident	74.2	Confident	13 Å²	13	25.7 Å²	25.7	7%	0.068	14%	0.136	C	C	.	.	H	α-helix	trans	-63.8	-49	174.6	179.2	72.6	0	0	0	111.5	L29 F44 L340 I356 V357 L358 Q362 I363 M364	L29-L360 HydrophobicContact CD1-CD2 3.69Å; L29-L360 HydrophobicContact CD2-CD2 3.64Å; L29-L360 HydrophobicContact CG-CD2 4.32Å; F44-L360 HydrophobicContact CD2-CD2 4.38Å; F44-L360 HydrophobicContact CE2-CD2 3.66Å; F44-L360 HydrophobicContact CE2-CG 4Å; F44-L360 HydrophobicContact CZ-CD2 4.39Å; L340-L360 HydrophobicContact CB-CD1 3.31Å; L340-L360 HydrophobicContact CD1-CD1 3.42Å; L340-L360 VanDerWaalsContact CD1-CD1 3.42Å; L340-L360 HydrophobicContact CD2-CD1 4.1Å; L340-L360 HydrophobicContact CG-CD1 3.77Å; I356-L360 WeakPolarHBondContact O-CB 3.4Å; I356-L360 PolarHBondContact O-N 2.61Å; V357-L360 WeakPolarHBondContact O-CB 3.48Å; V357-L360 PolarHBondContact O-N 2.96Å; L358-L360 PolarHBondContact O-N 3.47Å; L360-Q362 PolarHBondContact O-N 3.01Å; L360-I363 PolarHBondContact O-N 3.26Å; L360-M364 WeakPolarHBondContact O-CB 3.34Å; L360-M364 PolarHBondContact O-N 3.41Å
361	A	83.8	Confident	75.1	Confident	0 Å²	0	22.5 Å²	22.5	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-56.9	-41.6	175	0	0	0	0	0	111	F44 V357 L358 G365	F44-A361 HydrophobicContact CB-CB 4.48Å; F44-A361 HydrophobicContact CD2-CB 3.98Å; V357-A361 PolarHBondContact O-N 2.55Å; L358-A361 PolarHBondContact O-N 3.43Å; A361-G365 PolarHBondContact O-N 3.47Å
362	Q	84.2	Confident	76.2	Confident	23 Å²	23	14.7 Å²	14.7	11%	0.107	8%	0.08	C	C	.	.	H	α-helix	trans	-61	-55.2	176.5	-170.2	62.8	20.2	0	0	111.7	L86 V90 L358 L359 L360 M364 G365 M366	L86-Q362 PolarHBondContact O-NE2 2.79Å; L86-Q362 PolarHBondContact O-OE1 2.75Å; L86-Q362 VanDerWaalsContact O-OE1 3.05Å; V90-Q362 VanDerWaalsContact CB-OE1 3.28Å; V90-Q362 HydrophobicContact CG1-CB 3.77Å; V90-Q362 HydrophobicContact CG1-CG 4.42Å; L358-Q362 WeakPolarHBondContact O-CB 3.38Å; L358-Q362 PolarHBondContact O-N 2.9Å; L359-Q362 WeakPolarHBondContact O-CB 3.32Å; L359-Q362 PolarHBondContact O-N 3.02Å; L360-Q362 PolarHBondContact O-N 3.01Å; Q362-M364 VanDerWaalsContact C-N 3.31Å; Q362-M364 PolarHBondContact O-N 3.37Å; Q362-G365 PolarHBondContact O-N 3.48Å; Q362-M366 HydrophobicContact CG-CE 3.82Å; Q362-M366 HydrophobicContact CG-SD 4.15Å; Q362-M366 WeakPolarHBondContact O-CB 3.13Å; Q362-M366 WeakPolarHBondContact O-CG 3.25Å; Q362-M366 PolarHBondContact O-N 3.16Å
363	I	79.6	Confident	76.8	Confident	43 Å²	43	13.1 Å²	13.1	22%	0.221	7%	0.069	C	C	.	.	H	α-helix	trans	-59.6	-45.4	-179.2	-72.7	169.3	0	0	0	110.6	L134 L340 L359 L360 M366 Y367	L134-I363 HydrophobicContact CD1-CB 4.33Å; L134-I363 HydrophobicContact CD1-CG1 3.94Å; L134-I363 HydrophobicContact CD1-CG2 4.09Å; L340-I363 HydrophobicContact CD1-CG2 3.94Å; L340-I363 HydrophobicContact CD2-CG2 4.16Å; L359-I363 WeakPolarHBondContact O-CB 3.32Å; L359-I363 VanDerWaalsContact O-CG1 3.31Å; L359-I363 WeakPolarHBondContact O-CG1 3.39Å; L359-I363 PolarHBondContact O-N 2.93Å; L360-I363 PolarHBondContact O-N 3.26Å; I363-M366 HydrophobicContact CG1-CE 4.4Å; I363-Y367 VanDerWaalsContact O-CB 3.31Å; I363-Y367 WeakPolarHBondContact O-CB 3.27Å; I363-Y367 PolarHBondContact O-N 3.24Å
364	M	81.4	Confident	76.9	Confident	1 Å²	1	14.5 Å²	14.5	1%	0.005	8%	0.076	C	C	.	.	H	α-helix	trans	-60.9	-56.2	178.4	-177.5	-172.1	71.7	0	0	110.9	F44 T47 F48 L336 L337 L360 Q362 M366 Y367 F368	F44-M364 HydrophobicContact CE2-CE 4.28Å; F44-M364 HydrophobicContact CE2-SD 4.3Å; F44-M364 HydrophobicContact CZ-CE 4.5Å; F44-M364 HydrophobicContact CZ-SD 4.28Å; T47-M364 HydrophobicContact CG2-CE 4.08Å; F48-M364 HydrophobicContact CB-CE 3.8Å; F48-M364 HydrophobicContact CD2-CE 4.17Å; F48-M364 HydrophobicContact CD2-SD 3.82Å; L336-M364 HydrophobicContact CD2-CB 4.27Å; L336-M364 HydrophobicContact CD2-CG 4.09Å; L337-M364 HydrophobicContact CD2-SD 4.12Å; L360-M364 WeakPolarHBondContact O-CB 3.34Å; L360-M364 PolarHBondContact O-N 3.41Å; Q362-M364 VanDerWaalsContact C-N 3.31Å; Q362-M364 PolarHBondContact O-N 3.37Å; M364-M366 VanDerWaalsContact C-N 3.32Å; M364-M366 PolarHBondContact O-N 2.99Å; M364-Y367 WeakPolarHBondContact O-CB 3.35Å; M364-Y367 PolarHBondContact O-N 3.43Å; M364-Y367 VanDerWaalsContact O-N 3.09Å; M364-F368 HydrophobicContact CG-CD2 3.88Å; M364-F368 HydrophobicContact CG-CE2 3.54Å; M364-F368 WeakPolarHBondContact O-CD2 3.24Å; M364-F368 PolarHBondContact O-N 3.08Å; M364-F368 HydrophobicContact SD-CE2 4.42Å
365	G	81.2	Confident	76.6	Confident	0 Å²	0	14.4 Å²	14.4	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-65.1	-35.2	-177.8	0	0	0	0	0	113	L86 A361 Q362 Y367 F368 V369	L86-G365 VanDerWaalsContact CD1-C 3.41Å; A361-G365 PolarHBondContact O-N 3.47Å; Q362-G365 PolarHBondContact O-N 3.48Å; G365-Y367 VanDerWaalsContact C-N 3.31Å; G365-Y367 PolarHBondContact O-N 3.15Å; G365-F368 PolarHBondContact O-N 3.4Å; G365-V369 WeakPolarHBondContact O-CG2 3.33Å; G365-V369 PolarHBondContact O-N 3.36Å
366	M	80.5	Confident	76.3	Confident	9 Å²	9	15 Å²	15	4%	0.044	8%	0.076	C	C	.	.	H	α-helix	trans	-60.5	-41.4	172.3	-73	-170.7	-53.3	0	0	112.1	V127 I130 L134 Q362 I363 M364 S370	V127-M366 HydrophobicContact CG1-CG 3.8Å; I130-M366 HydrophobicContact CB-CE 4.37Å; I130-M366 HydrophobicContact CB-SD 3.81Å; I130-M366 HydrophobicContact CG2-CE 3.44Å; I130-M366 VanDerWaalsContact CG2-CE 3.44Å; I130-M366 HydrophobicContact CG2-SD 3.52Å; I130-M366 VanDerWaalsContact CG2-SD 3.52Å; L134-M366 HydrophobicContact CD1-CE 3.68Å; Q362-M366 HydrophobicContact CG-CE 3.82Å; Q362-M366 HydrophobicContact CG-SD 4.15Å; Q362-M366 WeakPolarHBondContact O-CB 3.13Å; Q362-M366 WeakPolarHBondContact O-CG 3.25Å; Q362-M366 PolarHBondContact O-N 3.16Å; I363-M366 HydrophobicContact CG1-CE 4.4Å; M364-M366 VanDerWaalsContact C-N 3.32Å; M364-M366 PolarHBondContact O-N 2.99Å; M366-S370 VanDerWaalsContact O-CB 3.31Å; M366-S370 WeakPolarHBondContact O-CB 3.36Å; M366-S370 PolarHBondContact O-N 2.98Å; M366-S370 PolarHBondContact O-OG 3.38Å
367	Y	77.8	Confident	75.8	Confident	20 Å²	20	17.4 Å²	17.4	8%	0.078	9%	0.087	C	C	.	.	H	α-helix	trans	-63.4	-44.8	176.4	-179.7	-89	0	0	0	112.3	M135 S332 L336 I363 M364 G365 S370 S371	M135-Y367 HydrophobicContact CB-CD2 3.73Å; M135-Y367 HydrophobicContact CB-CE2 3.69Å; M135-Y367 HydrophobicContact CG-CD2 4Å; M135-Y367 HydrophobicContact CG-CE2 3.47Å; M135-Y367 VanDerWaalsContact CG-CE2 3.47Å; M135-Y367 HydrophobicContact SD-CE2 4.32Å; S332-Y367 WeakPolarHBondContact CB-OH 3.32Å; L336-Y367 HydrophobicContact CD1-CD1 3.54Å; L336-Y367 HydrophobicContact CD1-CD2 3.4Å; L336-Y367 HydrophobicContact CD1-CE1 4.02Å; L336-Y367 HydrophobicContact CD1-CE2 3.86Å; L336-Y367 HydrophobicContact CD1-CG 3.2Å; I363-Y367 VanDerWaalsContact O-CB 3.31Å; I363-Y367 WeakPolarHBondContact O-CB 3.27Å; I363-Y367 PolarHBondContact O-N 3.24Å; M364-Y367 WeakPolarHBondContact O-CB 3.35Å; M364-Y367 PolarHBondContact O-N 3.43Å; M364-Y367 VanDerWaalsContact O-N 3.09Å; G365-Y367 VanDerWaalsContact C-N 3.31Å; G365-Y367 PolarHBondContact O-N 3.15Å; Y367-S370 PolarHBondContact O-N 3.35Å; Y367-S371 WeakPolarHBondContact CE1-OG 3.28Å; Y367-S371 WeakPolarHBondContact O-CB 3.43Å; Y367-S371 PolarHBondContact O-N 3.46Å; Y367-S371 PolarHBondContact O-OG 3.43Å
368	F	76.8	Confident	74.9	Confident	0 Å²	0	19 Å²	19	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-65	-46.8	-179.9	-85.3	-114.2	0	0	0	111.3	S51 F55 I333 M364 G365 S370 S371 V372	S51-F368 WeakPolarHBondContact O-CD1 3.32Å; F55-F368 AromaticContact CD2-CD1 3.56Å; F55-F368 HydrophobicContact CD2-CD1 3.56Å; F55-F368 AromaticContact CD2-CE1 3.64Å; F55-F368 HydrophobicContact CD2-CE1 3.64Å; F55-F368 AromaticContact CE2-CD1 2.98Å; F55-F368 HydrophobicContact CE2-CD1 2.98Å; F55-F368 AromaticContact CE2-CE1 3.25Å; F55-F368 HydrophobicContact CE2-CE1 3.25Å; F55-F368 AromaticContact CE2-CG 3.92Å; F55-F368 HydrophobicContact CE2-CG 3.92Å; F55-F368 HydrophobicContact CE2-CZ 4.31Å; F55-F368 AromaticContact CZ-CD1 3.84Å; F55-F368 HydrophobicContact CZ-CD1 3.84Å; F55-F368 HydrophobicContact CZ-CE1 4.4Å; F55-F368 HydrophobicContact CZ-CG 4.43Å; I333-F368 HydrophobicContact CB-CZ 4.16Å; I333-F368 HydrophobicContact CD1-CE1 3.62Å; I333-F368 HydrophobicContact CD1-CZ 3.79Å; I333-F368 HydrophobicContact CG1-CE1 3.75Å; I333-F368 HydrophobicContact CG1-CE2 4.13Å; I333-F368 HydrophobicContact CG1-CZ 3.5Å; I333-F368 VanDerWaalsContact CG1-CZ 3.5Å; I333-F368 HydrophobicContact CG2-CE2 4.32Å; I333-F368 HydrophobicContact CG2-CZ 3.67Å; M364-F368 HydrophobicContact CG-CD2 3.88Å; M364-F368 HydrophobicContact CG-CE2 3.54Å; M364-F368 WeakPolarHBondContact O-CD2 3.24Å; M364-F368 PolarHBondContact O-N 3.08Å; M364-F368 HydrophobicContact SD-CE2 4.42Å; G365-F368 PolarHBondContact O-N 3.4Å; F368-S370 VanDerWaalsContact C-N 3.29Å; F368-S370 PolarHBondContact O-N 2.88Å; F368-S371 PolarHBondContact O-N 3.42Å; F368-V372 WeakPolarHBondContact O-CG2 3.38Å; F368-V372 PolarHBondContact O-N 3.05Å
369	V	77.8	Confident	74.1	Confident	12 Å²	12	19.8 Å²	19.8	7%	0.073	10%	0.102	C	C	.	.	H	α-helix	trans	-58.2	-44	174.9	172.8	0	0	0	0	110.7	I82 L86 G365 S371 V372 L373	I82-V369 HydrophobicContact CD1-CG2 4.06Å; I82-V369 HydrophobicContact CG1-CG2 4.35Å; I82-V369 HydrophobicContact CG2-CG2 4.16Å; L86-V369 HydrophobicContact CD1-CG2 3.93Å; G365-V369 WeakPolarHBondContact O-CG2 3.33Å; G365-V369 PolarHBondContact O-N 3.36Å; V369-S371 PolarHBondContact O-N 2.94Å; V369-V372 PolarHBondContact O-N 3.42Å; V369-L373 WeakPolarHBondContact O-CG 3.46Å; V369-L373 PolarHBondContact O-N 3.1Å
370	S	75.3	Confident	73.3	Confident	0 Å²	0	18.1 Å²	18.1	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-66.8	-37.3	178.7	-57.7	0	0	0	0	113	G128 G131 V132 M366 Y367 F368 V372 L373 L374	G128-S370 PolarHBondContact O-OG 2.96Å; G131-S370 WeakPolarHBondContact CA-OG 3.4Å; V132-S370 PolarHBondContact N-OG 3.24Å; V132-S370 VanDerWaalsContact N-OG 3.08Å; M366-S370 VanDerWaalsContact O-CB 3.31Å; M366-S370 WeakPolarHBondContact O-CB 3.36Å; M366-S370 PolarHBondContact O-N 2.98Å; M366-S370 PolarHBondContact O-OG 3.38Å; Y367-S370 PolarHBondContact O-N 3.35Å; F368-S370 VanDerWaalsContact C-N 3.29Å; F368-S370 PolarHBondContact O-N 2.88Å; S370-V372 VanDerWaalsContact C-N 3.35Å; S370-L373 WeakPolarHBondContact O-CB 3.32Å; S370-L373 PolarHBondContact O-N 3.35Å; S370-L374 WeakPolarHBondContact O-CG 3.41Å; S370-L374 PolarHBondContact O-N 3.33Å
371	S	73	Confident	72.6	Confident	9 Å²	9	23 Å²	23	6%	0.063	12%	0.121	C	C	.	.	H	α-helix	trans	-63.3	-42.7	176.2	-62.4	0	0	0	0	111	Y367 F368 V369 L374 I375	Y367-S371 WeakPolarHBondContact CE1-OG 3.28Å; Y367-S371 WeakPolarHBondContact O-CB 3.43Å; Y367-S371 PolarHBondContact O-N 3.46Å; Y367-S371 PolarHBondContact O-OG 3.43Å; F368-S371 PolarHBondContact O-N 3.42Å; V369-S371 PolarHBondContact O-N 2.94Å; S371-L374 PolarHBondContact O-N 3.02Å; S371-I375 WeakPolarHBondContact O-CB 3.33Å; S371-I375 PolarHBondContact O-N 2.99Å
372	V	72.9	Confident	71.7	Confident	2 Å²	2	27.6 Å²	27.6	1%	0.012	14%	0.143	C	C	.	.	H	α-helix	trans	-64.5	-39.5	175.6	174.1	0	0	0	0	111.7	M54 F55 I58 W75 F368 V369 S370 L374 I375	M54-V372 HydrophobicContact CB-CG2 4.05Å; M54-V372 HydrophobicContact CE-CB 4.42Å; M54-V372 HydrophobicContact CE-CG1 3.99Å; M54-V372 HydrophobicContact CE-CG2 4.41Å; F55-V372 HydrophobicContact CD1-CG2 4.22Å; F55-V372 HydrophobicContact CE1-CG2 3.86Å; F55-V372 HydrophobicContact CZ-CG2 4.5Å; I58-V372 HydrophobicContact CD1-CB 4.42Å; I58-V372 HydrophobicContact CD1-CG1 4.09Å; I58-V372 HydrophobicContact CD1-CG2 3.88Å; W75-V372 HydrophobicContact CH2-CG1 3.91Å; W75-V372 HydrophobicContact CZ3-CG1 3.99Å; F368-V372 WeakPolarHBondContact O-CG2 3.38Å; F368-V372 PolarHBondContact O-N 3.05Å; V369-V372 PolarHBondContact O-N 3.42Å; S370-V372 VanDerWaalsContact C-N 3.35Å; V372-L374 VanDerWaalsContact C-N 3.3Å; V372-L374 PolarHBondContact O-N 3.27Å; V372-I375 VanDerWaalsContact O-CG2 3.31Å; V372-I375 WeakPolarHBondContact O-CG2 3.2Å; V372-I375 PolarHBondContact O-N 2.92Å
373	L	70.2	Confident	70.9	Confident	8 Å²	8	28.7 Å²	28.7	4%	0.042	15%	0.147	C	C	.	.	H	α-helix	trans	-60	-41.5	174.6	-70.2	174.3	0	0	0	112	V369 S370 L391 L394 F396	V369-L373 WeakPolarHBondContact O-CG 3.46Å; V369-L373 PolarHBondContact O-N 3.1Å; S370-L373 WeakPolarHBondContact O-CB 3.32Å; S370-L373 PolarHBondContact O-N 3.35Å; L373-L391 HydrophobicContact CD2-CD1 3.87Å; L373-L391 HydrophobicContact CD2-CD2 3.43Å; L373-L391 VanDerWaalsContact CD2-CD2 3.43Å; L373-L391 HydrophobicContact CD2-CG 4.28Å; L373-L394 HydrophobicContact CD2-CD1 4.27Å; L373-F396 HydrophobicContact CD2-CE1 4.11Å
374	L	68.1	Low	70.5	Confident	31 Å²	31	31.3 Å²	31.3	16%	0.162	15%	0.153	C	C	.	.	H	α-helix	trans	-77.2	-31.3	-178.8	-66.5	173.9	0	0	0	112.6	M135 S370 S371 V372 R376 M377 F403	M135-L374 HydrophobicContact CE-CD1 4.02Å; M135-L374 HydrophobicContact SD-CD1 3.66Å; S370-L374 WeakPolarHBondContact O-CG 3.41Å; S370-L374 PolarHBondContact O-N 3.33Å; S371-L374 PolarHBondContact O-N 3.02Å; V372-L374 VanDerWaalsContact C-N 3.3Å; V372-L374 PolarHBondContact O-N 3.27Å; L374-R376 PolarHBondContact O-N 3.41Å; L374-M377 WeakPolarHBondContact O-CB 3.19Å; L374-M377 PolarHBondContact O-N 3.38Å; L374-M377 VanDerWaalsContact O-N 3.08Å; L374-F403 HydrophobicContact CD1-CD2 3.78Å; L374-F403 HydrophobicContact CD1-CE2 4.12Å; L374-F403 HydrophobicContact CD1-CG 4.21Å
375	I	68.1	Low	70.1	Confident	14 Å²	14	35.2 Å²	35.2	7%	0.072	18%	0.177	C	C	.	.	H	α-helix	trans	-64.6	-27.9	-179	-138.1	167.5	0	0	0	113.2	I58 V325 I329 S371 V372 M377 S378 M379	I58-I375 HydrophobicContact CD1-CD1 4.31Å; I58-I375 HydrophobicContact CD1-CG2 3.81Å; V325-I375 HydrophobicContact CG1-CD1 3.19Å; V325-I375 HydrophobicContact CG1-CG1 3.49Å; V325-I375 VanDerWaalsContact CG1-CG1 3.49Å; V325-I375 HydrophobicContact CG2-CG1 4.38Å; I329-I375 HydrophobicContact CD1-CD1 3.28Å; I329-I375 HydrophobicContact CG1-CD1 3.64Å; S371-I375 WeakPolarHBondContact O-CB 3.33Å; S371-I375 PolarHBondContact O-N 2.99Å; V372-I375 VanDerWaalsContact O-CG2 3.31Å; V372-I375 WeakPolarHBondContact O-CG2 3.2Å; V372-I375 PolarHBondContact O-N 2.92Å; I375-M377 PolarHBondContact O-N 2.95Å; I375-S378 WeakPolarHBondContact CA-OG 3.34Å; I375-S378 PolarHBondContact O-N 3.4Å; I375-S378 PolarHBondContact O-OG 3.27Å; I375-M379 HydrophobicContact CG2-CE 3.87Å; I375-M379 PolarHBondContact O-N 3.01Å
376	R	66.6	Low	69.8	Low	30 Å²	30	36.1 Å²	36.1	11%	0.113	18%	0.182	C	C	.	.	G	3₁₀ helix	trans	-55.9	-33.6	174.1	-178.1	-174.7	172.5	-124.1	-2.8	111.7	L374 S378 M379 R384 I387 T388 F396	L374-R376 PolarHBondContact O-N 3.41Å; R376-S378 VanDerWaalsContact C-N 3.29Å; R376-M379 PolarHBondContact O-N 3.39Å; R376-R384 HydrophobicContact CG-CB 4.27Å; R376-I387 HydrophobicContact CB-CG2 4.36Å; R376-I387 HydrophobicContact CG-CG2 4.27Å; R376-T388 VanDerWaalsContact CZ-OG1 3.25Å; R376-T388 PolarHBondContact NE-OG1 2.86Å; R376-T388 PolarHBondContact NH2-OG1 3.29Å; R376-F396 VanDerWaalsContact NH1-CG 3.32Å; R376-F396 VanDerWaalsContact NH1-CZ 3.28Å
377	M	60	Low	69.5	Low	72 Å²	72	35.7 Å²	35.7	36%	0.355	18%	0.18	S	C	.	.	G	3₁₀ helix	trans	-75.7	-19.8	179.3	-65.9	-62.1	-176.7	0	0	112.9	L374 I375 F396	L374-M377 WeakPolarHBondContact O-CB 3.19Å; L374-M377 PolarHBondContact O-N 3.38Å; L374-M377 VanDerWaalsContact O-N 3.08Å; I375-M377 PolarHBondContact O-N 2.95Å; M377-F396 HydrophobicContact CE-CB 3.37Å; M377-F396 HydrophobicContact CE-CG 4.13Å
378	S	59.8	Low	69.4	Low	34 Å²	34	36.7 Å²	36.7	24%	0.238	19%	0.188	C	C	.	.	G	3₁₀ helix	trans	-92.9	-1.2	174.2	50.8	0	0	0	0	114.1	I375 R376	I375-S378 WeakPolarHBondContact CA-OG 3.34Å; I375-S378 PolarHBondContact O-N 3.4Å; I375-S378 PolarHBondContact O-OG 3.27Å; R376-S378 VanDerWaalsContact C-N 3.29Å
379	M	63.9	Low	69.5	Low	15 Å²	15	42.3 Å²	42.3	7%	0.074	22%	0.215	C	C	.	.	S	Bend	trans	-102.9	142.1	-178	-73.5	-167.5	-64.4	0	0	112.7	I58 I62 I375 R376 I387	I58-M379 HydrophobicContact CG2-SD 4.02Å; I62-M379 HydrophobicContact CD1-SD 3.72Å; I62-M379 HydrophobicContact CG1-SD 4.15Å; I375-M379 HydrophobicContact CG2-CE 3.87Å; I375-M379 PolarHBondContact O-N 3.01Å; R376-M379 PolarHBondContact O-N 3.39Å; M379-I387 HydrophobicContact CE-CD1 3.35Å
380	P	60.3	Low	69.3	Low	44 Å²	44	42.9 Å²	42.9	29%	0.286	22%	0.218	S	C	.	.			trans	-57.7	157.1	174.3	-23.4	33	0	0	0	113.4	Q318 E382 Y383 R384	Q318-P380 HydrophobicContact CG-CG 4.4Å; P380-E382 PolarHBondContact O-N 2.84Å; P380-Y383 HydrophobicContact CB-CD2 4.25Å; P380-Y383 HydrophobicContact CG-CD2 4.38Å; P380-Y383 PolarHBondContact O-N 2.9Å; P380-R384 PolarHBondContact O-N 3.48Å
381	L	63.2	Low	69.1	Low	115 Å²	115	43.7 Å²	43.7	60%	0.602	22%	0.222	S	C	*	.	T	Hydrogen-bonded Turn	trans	-60.1	-24	-174.4	-44.8	179.9	0	0	0	113.8	R384	L381-R384 VanDerWaalsContact CD2-NH2 3.33Å; L381-R384 WeakPolarHBondContact O-CG 3.17Å
382	E	65.4	Low	69	Low	97 Å²	97	45 Å²	45	45%	0.453	24%	0.237	S	C	.	.	T	Hydrogen-bonded Turn	trans	-74.1	-32.1	-176.1	-65.5	164.7	-172.1	0	0	112.1	K314 P380 T385	K314-E382 WeakPolarHBondContact CE-OE1 3.5Å; K314-E382 IonicContact NZ-OE1 2.76Å; K314-E382 PolarHBondContact NZ-OE1 3.43Å; P380-E382 PolarHBondContact O-N 2.84Å; E382-T385 PolarHBondContact O-OG1 2.85Å
383	Y	67.4	Low	68.5	Low	47 Å²	47	54.5 Å²	54.5	18%	0.184	28%	0.281	C	S	.	.	T	Hydrogen-bonded Turn	trans	-99	-10.7	-176.5	-59.5	-72.7	0	0	0	113.8	E61 Q318 P380	E61-Y383 WeakPolarHBondContact O-CD1 3.22Å; Q318-Y383 HydrophobicContact CG-CE2 3.86Å; Q318-Y383 PolarHBondContact NE2-OH 3.02Å; P380-Y383 HydrophobicContact CB-CD2 4.25Å; P380-Y383 HydrophobicContact CG-CD2 4.38Å; P380-Y383 PolarHBondContact O-N 2.9Å
384	R	70.1	Confident	68.2	Low	97 Å²	97	55.3 Å²	55.3	37%	0.366	29%	0.285	S	S	.	.	S	Bend	trans	-85.4	-6.2	-177.3	74.3	-176.9	-175.6	169.7	5.9	113.7	R376 P380 L381 I387 T388	R376-R384 HydrophobicContact CG-CB 4.27Å; P380-R384 PolarHBondContact O-N 3.48Å; L381-R384 VanDerWaalsContact CD2-NH2 3.33Å; L381-R384 WeakPolarHBondContact O-CG 3.17Å; R384-I387 PolarHBondContact O-N 3.35Å; R384-T388 VanDerWaalsContact O-CB 3.3Å; R384-T388 WeakPolarHBondContact O-CB 3.26Å; R384-T388 PolarHBondContact O-N 3.3Å; R384-T388 PolarHBondContact O-OG1 2.81Å
385	T	73.8	Confident	68.1	Low	83 Å²	83	61.2 Å²	61.2	51%	0.509	31%	0.312	S	S	.	.	H	α-helix	trans	-64.1	-54.6	-167.2	-28.8	0	0	0	0	111.6	E382 I387 T388 E389	E382-T385 PolarHBondContact O-OG1 2.85Å; T385-I387 VanDerWaalsContact C-N 3.34Å; T385-I387 PolarHBondContact O-N 3.45Å; T385-T388 WeakPolarHBondContact O-CB 3.39Å; T385-T388 PolarHBondContact O-N 3.3Å; T385-E389 PolarHBondContact O-N 3.49Å
386	I	75.8	Confident	67.9	Low	19 Å²	19	61.5 Å²	61.5	10%	0.097	31%	0.313	C	S	.	.	H	α-helix	trans	-61.7	-43	178.4	-69.8	-179.6	0	0	0	111	E61 R71 Y72 W75 T388 E389 V390	E61-I386 WeakPolarHBondContact OE2-CD1 3.32Å; R71-I386 HydrophobicContact CB-CD1 4.46Å; Y72-I386 HydrophobicContact CD2-CG2 4.23Å; W75-I386 HydrophobicContact CG-CG2 4.32Å; I386-T388 VanDerWaalsContact C-N 3.34Å; I386-T388 PolarHBondContact O-N 3.45Å; I386-E389 PolarHBondContact O-N 3.49Å; I386-V390 HydrophobicContact CG2-CG2 4.27Å; I386-V390 WeakPolarHBondContact O-CB 3.31Å; I386-V390 VanDerWaalsContact O-CG2 3.25Å; I386-V390 WeakPolarHBondContact O-CG2 3.26Å; I386-V390 PolarHBondContact O-N 3.21Å
387	I	73.4	Confident	68	Low	0 Å²	0	64.5 Å²	64.5	0%	0	33%	0.331	C	S	.	.	H	α-helix	trans	-64.2	-40.4	179.6	-66.1	170.9	0	0	0	111.1	W75 R376 M379 R384 T385 L391	W75-I387 HydrophobicContact CH2-CD1 4.11Å; W75-I387 HydrophobicContact CH2-CG1 4.02Å; W75-I387 HydrophobicContact CZ2-CD1 3.85Å; W75-I387 HydrophobicContact CZ2-CG1 3.77Å; R376-I387 HydrophobicContact CB-CG2 4.36Å; R376-I387 HydrophobicContact CG-CG2 4.27Å; M379-I387 HydrophobicContact CE-CD1 3.35Å; R384-I387 PolarHBondContact O-N 3.35Å; T385-I387 VanDerWaalsContact C-N 3.34Å; T385-I387 PolarHBondContact O-N 3.45Å; I387-L391 HydrophobicContact CG2-CD1 3.43Å; I387-L391 VanDerWaalsContact CG2-CD1 3.43Å; I387-L391 HydrophobicContact CG2-CG 4.31Å; I387-L391 WeakPolarHBondContact O-CB 3.41Å; I387-L391 WeakPolarHBondContact O-CD1 3.25Å; I387-L391 WeakPolarHBondContact O-CG 3.48Å; I387-L391 PolarHBondContact O-N 2.81Å
388	T	75.1	Confident	68.5	Low	41 Å²	41	65.5 Å²	65.5	25%	0.252	33%	0.334	S	S	.	.	H	α-helix	trans	-63.6	-42.8	176.3	-56.8	0	0	0	0	111.4	R376 R384 T385 I386 G392	R376-T388 VanDerWaalsContact CZ-OG1 3.25Å; R376-T388 PolarHBondContact NE-OG1 2.86Å; R376-T388 PolarHBondContact NH2-OG1 3.29Å; R384-T388 VanDerWaalsContact O-CB 3.3Å; R384-T388 WeakPolarHBondContact O-CB 3.26Å; R384-T388 PolarHBondContact O-N 3.3Å; R384-T388 PolarHBondContact O-OG1 2.81Å; T385-T388 WeakPolarHBondContact O-CB 3.39Å; T385-T388 PolarHBondContact O-N 3.3Å; I386-T388 VanDerWaalsContact C-N 3.34Å; I386-T388 PolarHBondContact O-N 3.45Å; T388-G392 PolarHBondContact O-N 2.72Å
389	E	78.4	Confident	68.8	Low	119 Å²	119	64.4 Å²	64.4	56%	0.556	33%	0.325	S	S	*	.	H	α-helix	trans	-68.3	-42.1	-179.5	-166.3	-177.3	163.6	0	0	111.9	Y72 T385 I386 G392	Y72-E389 HydrophobicContact CE2-CB 4.27Å; Y72-E389 HydrophobicContact CE2-CG 3.89Å; T385-E389 PolarHBondContact O-N 3.49Å; I386-E389 PolarHBondContact O-N 3.49Å; E389-G392 PolarHBondContact O-N 2.94Å
390	V	74.7	Confident	69	Low	24 Å²	24	66 Å²	66	15%	0.145	33%	0.332	C	S	.	.	H	α-helix	trans	-71.3	-34.7	179.8	173.6	0	0	0	0	112	Y72 W75 L79 I386	Y72-V390 HydrophobicContact CD2-CG2 3.75Å; Y72-V390 HydrophobicContact CE2-CG2 3.67Å; W75-V390 HydrophobicContact CB-CG1 4.3Å; W75-V390 HydrophobicContact CB-CG2 4Å; L79-V390 HydrophobicContact CD1-CG1 4.18Å; I386-V390 HydrophobicContact CG2-CG2 4.27Å; I386-V390 WeakPolarHBondContact O-CB 3.31Å; I386-V390 VanDerWaalsContact O-CG2 3.25Å; I386-V390 WeakPolarHBondContact O-CG2 3.26Å; I386-V390 PolarHBondContact O-N 3.21Å
391	L	71.4	Confident	69.6	Low	17 Å²	17	69.4 Å²	69.4	9%	0.089	34%	0.339	C	S	.	.	H	α-helix	trans	-80.1	-16.9	177.4	-72.3	169	0	0	0	113.5	L79 L373 I387 L394 F396	L79-L391 HydrophobicContact CD1-CD2 3.72Å; L373-L391 HydrophobicContact CD2-CD1 3.87Å; L373-L391 HydrophobicContact CD2-CD2 3.43Å; L373-L391 VanDerWaalsContact CD2-CD2 3.43Å; L373-L391 HydrophobicContact CD2-CG 4.28Å; I387-L391 HydrophobicContact CG2-CD1 3.43Å; I387-L391 VanDerWaalsContact CG2-CD1 3.43Å; I387-L391 HydrophobicContact CG2-CG 4.31Å; I387-L391 WeakPolarHBondContact O-CB 3.41Å; I387-L391 WeakPolarHBondContact O-CD1 3.25Å; I387-L391 WeakPolarHBondContact O-CG 3.48Å; I387-L391 PolarHBondContact O-N 2.81Å; L391-L394 HydrophobicContact CB-CD1 4.18Å; L391-L394 HydrophobicContact CD2-CD1 4.24Å; L391-L394 VanDerWaalsContact O-CD1 3.28Å; L391-L394 WeakPolarHBondContact O-CD1 3.47Å; L391-L394 WeakPolarHBondContact O-CG 3.3Å; L391-F396 HydrophobicContact CB-CZ 3.91Å; L391-F396 HydrophobicContact CD1-CE1 4.05Å; L391-F396 HydrophobicContact CD1-CZ 4.12Å
392	G	70.4	Confident	70	Confident	35 Å²	35	68.1 Å²	68.1	36%	0.361	33%	0.326	S	S	.	.			trans	69.2	-164.9	-178.1	0	0	0	0	0	114.1	T388 E389 L394	T388-G392 PolarHBondContact O-N 2.72Å; E389-G392 PolarHBondContact O-N 2.94Å; G392-L394 PolarHBondContact O-N 3.43Å
393	E	62.8	Low	70.4	Confident	202 Å²	202	64.2 Å²	64.2	94%	0.944	31%	0.308	S	S	*	.	S	Bend	trans	-78.3	44.7	-179.6	-60.9	-167.9	167.3	0	0	113.2	Q395	E393-Q395 PolarHBondContact O-N 2.91Å
394	L	64.3	Low	70.8	Confident	26 Å²	26	62.5 Å²	62.5	14%	0.136	30%	0.302	C	S	.	.			trans	-60.1	138.5	172.7	-73.3	165.3	0	0	0	109.7	I124 L373 L391 G392 F396 Y399	I124-L394 HydrophobicContact CG2-CD1 3.84Å; I124-L394 HydrophobicContact CG2-CD2 4.02Å; L373-L394 HydrophobicContact CD2-CD1 4.27Å; L391-L394 HydrophobicContact CB-CD1 4.18Å; L391-L394 HydrophobicContact CD2-CD1 4.24Å; L391-L394 VanDerWaalsContact O-CD1 3.28Å; L391-L394 WeakPolarHBondContact O-CD1 3.47Å; L391-L394 WeakPolarHBondContact O-CG 3.3Å; G392-L394 PolarHBondContact O-N 3.43Å; L394-F396 HydrophobicContact CB-CD1 4.49Å; L394-F396 HydrophobicContact CB-CD2 4.17Å; L394-F396 HydrophobicContact CB-CE1 4.07Å; L394-F396 HydrophobicContact CB-CE2 3.69Å; L394-F396 HydrophobicContact CB-CZ 3.66Å; L394-F396 HydrophobicContact CD1-CE1 4.34Å; L394-F396 HydrophobicContact CD1-CZ 4.2Å; L394-F396 HydrophobicContact CG-CZ 4.49Å; L394-F396 WeakPolarHBondContact O-CD2 3.45Å; L394-F396 WeakPolarHBondContact O-CE2 3.35Å; L394-F396 PolarHBondContact O-N 3.45Å; L394-Y399 HydrophobicContact CB-CE2 4.49Å; L394-Y399 HydrophobicContact CD2-CE2 4.4Å
395	Q	64.6	Low	71.1	Confident	154 Å²	154	60.2 Å²	60.2	72%	0.72	30%	0.298	S	S	*	.			trans	-75.5	74.9	173.8	-69.1	-172.7	-13.9	0	0	110.1	E393 N397 F398 Y399	E393-Q395 PolarHBondContact O-N 2.91Å; Q395-N397 PolarHBondContact O-N 3.47Å; Q395-N397 VanDerWaalsContact O-N 3.08Å; Q395-F398 HydrophobicContact CB-CB 4.43Å; Q395-F398 VanDerWaalsContact O-CB 3.28Å; Q395-F398 WeakPolarHBondContact O-CB 3.38Å; Q395-F398 PolarHBondContact O-N 3.5Å; Q395-Y399 WeakPolarHBondContact O-CD2 3.27Å
396	F	65.5	Low	71.3	Confident	20 Å²	20	57.7 Å²	57.7	9%	0.088	28%	0.281	C	S	.	.	H	α-helix	trans	-57.5	-28	-174.6	-63.7	-85.6	0	0	0	114.1	L373 R376 M377 L391 L394 F398 Y399 H400	L373-F396 HydrophobicContact CD2-CE1 4.11Å; R376-F396 VanDerWaalsContact NH1-CG 3.32Å; R376-F396 VanDerWaalsContact NH1-CZ 3.28Å; M377-F396 HydrophobicContact CE-CB 3.37Å; M377-F396 HydrophobicContact CE-CG 4.13Å; L391-F396 HydrophobicContact CB-CZ 3.91Å; L391-F396 HydrophobicContact CD1-CE1 4.05Å; L391-F396 HydrophobicContact CD1-CZ 4.12Å; L394-F396 HydrophobicContact CB-CD1 4.49Å; L394-F396 HydrophobicContact CB-CD2 4.17Å; L394-F396 HydrophobicContact CB-CE1 4.07Å; L394-F396 HydrophobicContact CB-CE2 3.69Å; L394-F396 HydrophobicContact CB-CZ 3.66Å; L394-F396 HydrophobicContact CD1-CE1 4.34Å; L394-F396 HydrophobicContact CD1-CZ 4.2Å; L394-F396 HydrophobicContact CG-CZ 4.49Å; L394-F396 WeakPolarHBondContact O-CD2 3.45Å; L394-F396 WeakPolarHBondContact O-CE2 3.35Å; L394-F396 PolarHBondContact O-N 3.45Å; F396-F398 PolarHBondContact O-N 3.45Å; F396-Y399 PolarHBondContact O-N 3.04Å; F396-H400 PolarHBondContact O-N 2.96Å
397	N	66.8	Low	71.3	Confident	93 Å²	93	56.8 Å²	56.8	50%	0.497	28%	0.277	S	S	.	.	H	α-helix	trans	-57.9	-37.6	174.9	-61.4	-8.3	0	0	0	111.6	V290 Q395 R401	V290-N397 WeakPolarHBondContact CG1-OD1 3.23Å; V290-N397 HydrophobicContact CG2-CB 4.14Å; Q395-N397 PolarHBondContact O-N 3.47Å; Q395-N397 VanDerWaalsContact O-N 3.08Å; N397-R401 WeakPolarHBondContact O-CB 3.17Å; N397-R401 PolarHBondContact O-N 3.31Å
398	F	70.4	Confident	71.7	Confident	94 Å²	94	58 Å²	58	41%	0.412	28%	0.283	S	S	.	.	H	α-helix	trans	-63.1	-48.5	176.3	171.6	-97.7	0	0	0	111.3	V129 Q395 F396 H400 R401 W402	V129-F398 HydrophobicContact CG2-CE1 3.73Å; V129-F398 HydrophobicContact CG2-CZ 4.37Å; Q395-F398 HydrophobicContact CB-CB 4.43Å; Q395-F398 VanDerWaalsContact O-CB 3.28Å; Q395-F398 WeakPolarHBondContact O-CB 3.38Å; Q395-F398 PolarHBondContact O-N 3.5Å; F396-F398 PolarHBondContact O-N 3.45Å; F398-H400 PolarHBondContact O-N 3.1Å; F398-R401 PolarHBondContact O-N 3.38Å; F398-W402 HydrophobicContact CE2-CE3 4.34Å; F398-W402 HydrophobicContact CZ-CD2 4.46Å; F398-W402 HydrophobicContact CZ-CE3 4.09Å; F398-W402 WeakPolarHBondContact O-CB 3.35Å; F398-W402 PolarHBondContact O-N 2.97Å
399	Y	67.1	Low	72	Confident	11 Å²	11	60.3 Å²	60.3	4%	0.043	30%	0.297	C	S	.	.	H	α-helix	trans	-66.1	-37.3	-178.4	-64.5	-90	0	0	0	112.7	S125 V129 V132 L394 Q395 F396 W402 F403	S125-Y399 WeakPolarHBondContact CA-OH 3.48Å; S125-Y399 WeakPolarHBondContact CB-OH 3.27Å; V129-Y399 HydrophobicContact CG2-CE1 4.33Å; V132-Y399 HydrophobicContact CG2-CD1 4.36Å; L394-Y399 HydrophobicContact CB-CE2 4.49Å; L394-Y399 HydrophobicContact CD2-CE2 4.4Å; Q395-Y399 WeakPolarHBondContact O-CD2 3.27Å; F396-Y399 PolarHBondContact O-N 3.04Å; Y399-W402 PolarHBondContact O-N 2.95Å; Y399-F403 WeakPolarHBondContact O-CB 3.11Å; Y399-F403 PolarHBondContact O-N 3.26Å
400	H	67.9	Low	71.9	Confident	48 Å²	48	55 Å²	55	22%	0.222	27%	0.273	C	S	.	.	H	α-helix	trans	-67.1	-46.1	176.3	-168.8	-67.9	0	0	0	111.4	F396 F398 W402 F403 D404	F396-H400 PolarHBondContact O-N 2.96Å; F398-H400 PolarHBondContact O-N 3.1Å; H400-W402 VanDerWaalsContact C-N 3.31Å; H400-W402 PolarHBondContact O-N 3.42Å; H400-F403 WeakPolarHBondContact O-CB 3.33Å; H400-F403 PolarHBondContact O-N 3.43Å; H400-D404 IonicContact CE1-OD1 2.71Å; H400-D404 IonicContact CE1-OD2 2.88Å; H400-D404 PolarHBondContact CE1-OD2 2.94Å; H400-D404 IonicContact ND1-OD2 3.56Å; H400-D404 PolarHBondContact ND1-OD2 3.4Å; H400-D404 VanDerWaalsContact ND1-OD2 3.16Å; H400-D404 PolarHBondContact O-N 3.23Å
401	R	72.7	Confident	71.8	Confident	115 Å²	115	53.9 Å²	53.9	43%	0.434	27%	0.266	S	S	.	.	H	α-helix	trans	-62.9	-41	175.9	-176.6	170.8	171.9	165.8	-4.8	111.2	D288 N397 F398 D404 V405	D288-R401 IonicContact OD1-CZ 3.67Å; D288-R401 IonicContact OD1-NH1 2.75Å; D288-R401 PolarHBondContact OD1-NH1 3.07Å; D288-R401 IonicContact OD2-NH1 3.87Å; D288-R401 PolarHBondContact OD2-NH1 3.29Å; N397-R401 WeakPolarHBondContact O-CB 3.17Å; N397-R401 PolarHBondContact O-N 3.31Å; F398-R401 PolarHBondContact O-N 3.38Å; R401-D404 PolarHBondContact O-N 2.96Å; R401-V405 WeakPolarHBondContact O-CB 3.12Å; R401-V405 VanDerWaalsContact O-CG2 3.23Å; R401-V405 WeakPolarHBondContact O-CG2 3.19Å; R401-V405 PolarHBondContact O-N 3.28Å
402	W	72.8	Confident	72.5	Confident	89 Å²	89	57.6 Å²	57.6	34%	0.337	29%	0.285	S	S	.	.	H	α-helix	trans	-61.1	-44.1	174.9	-170	-95.7	0	0	0	111.6	V129 T133 F398 Y399 H400 V405 I406	V129-W402 HydrophobicContact CG1-CZ2 4.09Å; T133-W402 PolarHBondContact OG1-NE1 2.95Å; F398-W402 HydrophobicContact CE2-CE3 4.34Å; F398-W402 HydrophobicContact CZ-CD2 4.46Å; F398-W402 HydrophobicContact CZ-CE3 4.09Å; F398-W402 WeakPolarHBondContact O-CB 3.35Å; F398-W402 PolarHBondContact O-N 2.97Å; Y399-W402 PolarHBondContact O-N 2.95Å; H400-W402 VanDerWaalsContact C-N 3.31Å; H400-W402 PolarHBondContact O-N 3.42Å; W402-V405 PolarHBondContact O-N 3.3Å; W402-I406 HydrophobicContact CZ2-CD1 4.32Å; W402-I406 WeakPolarHBondContact O-CG1 3.11Å; W402-I406 PolarHBondContact O-N 3.02Å
403	F	73.4	Confident	73.1	Confident	15 Å²	15	58.9 Å²	58.9	7%	0.066	29%	0.289	C	S	.	.	H	α-helix	trans	-57.8	-52.5	173.7	179.2	-93.4	0	0	0	111.7	V132 M135 A136 L374 Y399 H400 V405 I406 F407	V132-F403 HydrophobicContact CG1-CB 3.59Å; V132-F403 HydrophobicContact CG1-CD2 4.03Å; V132-F403 HydrophobicContact CG1-CG 4.32Å; M135-F403 HydrophobicContact CB-CE2 4.42Å; M135-F403 HydrophobicContact CG-CE2 3.98Å; M135-F403 HydrophobicContact SD-CE2 4.38Å; A136-F403 HydrophobicContact CB-CD2 3.68Å; A136-F403 HydrophobicContact CB-CE2 3.84Å; A136-F403 HydrophobicContact CB-CG 4.34Å; A136-F403 WeakPolarHBondContact CB-O 3.34Å; L374-F403 HydrophobicContact CD1-CD2 3.78Å; L374-F403 HydrophobicContact CD1-CE2 4.12Å; L374-F403 HydrophobicContact CD1-CG 4.21Å; Y399-F403 WeakPolarHBondContact O-CB 3.11Å; Y399-F403 PolarHBondContact O-N 3.26Å; H400-F403 WeakPolarHBondContact O-CB 3.33Å; H400-F403 PolarHBondContact O-N 3.43Å; F403-V405 VanDerWaalsContact C-N 3.31Å; F403-V405 PolarHBondContact O-N 2.92Å; F403-I406 PolarHBondContact O-N 3.4Å; F403-F407 HydrophobicContact CE1-CB 4.29Å; F403-F407 WeakPolarHBondContact O-CB 3.23Å; F403-F407 PolarHBondContact O-N 3.4Å
404	D	75.8	Confident	73.7	Confident	11 Å²	11	49.8 Å²	49.8	6%	0.059	25%	0.248	C	C	.	.	H	α-helix	trans	-60.3	-41.7	-177.6	-77.1	-15.6	0	0	0	111.4	A281 N284 I285 H400 R401 F407 L408	A281-D404 HydrophobicContact CB-CB 4.25Å; N284-D404 WeakPolarHBondContact CB-OD2 3.39Å; N284-D404 PolarHBondContact ND2-OD2 2.71Å; I285-D404 HydrophobicContact CD1-CB 4.22Å; I285-D404 HydrophobicContact CG1-CB 4.09Å; H400-D404 IonicContact CE1-OD1 2.71Å; H400-D404 IonicContact CE1-OD2 2.88Å; H400-D404 PolarHBondContact CE1-OD2 2.94Å; H400-D404 IonicContact ND1-OD2 3.56Å; H400-D404 PolarHBondContact ND1-OD2 3.4Å; H400-D404 VanDerWaalsContact ND1-OD2 3.16Å; H400-D404 PolarHBondContact O-N 3.23Å; R401-D404 PolarHBondContact O-N 2.96Å; D404-F407 PolarHBondContact O-N 2.94Å; D404-L408 WeakPolarHBondContact O-CB 3.22Å; D404-L408 PolarHBondContact O-N 2.85Å
405	V	77.1	Confident	74.7	Confident	49 Å²	49	52.3 Å²	52.3	30%	0.297	26%	0.261	S	S	.	.	H	α-helix	trans	-62.5	-52.9	177.6	170.1	0	0	0	0	111.2	I285 R401 W402 F403 F407 L408 V409	I285-V405 HydrophobicContact CD1-CB 4.47Å; I285-V405 HydrophobicContact CD1-CG2 3.9Å; I285-V405 HydrophobicContact CG1-CG2 3.94Å; I285-V405 HydrophobicContact CG2-CG2 4.47Å; R401-V405 WeakPolarHBondContact O-CB 3.12Å; R401-V405 VanDerWaalsContact O-CG2 3.23Å; R401-V405 WeakPolarHBondContact O-CG2 3.19Å; R401-V405 PolarHBondContact O-N 3.28Å; W402-V405 PolarHBondContact O-N 3.3Å; F403-V405 VanDerWaalsContact C-N 3.31Å; F403-V405 PolarHBondContact O-N 2.92Å; V405-F407 VanDerWaalsContact C-N 3.3Å; V405-F407 PolarHBondContact O-N 3.27Å; V405-L408 PolarHBondContact O-N 2.99Å; V405-V409 WeakPolarHBondContact O-CG2 3.46Å; V405-V409 PolarHBondContact O-N 2.91Å
406	I	76.4	Confident	75.6	Confident	29 Å²	29	49.8 Å²	49.8	15%	0.149	25%	0.252	C	S	.	.	H	α-helix	trans	-66.1	-36.9	-178.6	-60.6	-62.5	0	0	0	110.9	T133 A136 L137 W402 F403 V409 S410	T133-I406 HydrophobicContact CG2-CD1 4.35Å; T133-I406 HydrophobicContact CG2-CG1 4.31Å; T133-I406 HydrophobicContact CG2-CG2 3.95Å; A136-I406 HydrophobicContact CB-CB 3.61Å; A136-I406 HydrophobicContact CB-CG2 3.55Å; L137-I406 HydrophobicContact CD2-CG2 3.82Å; L137-I406 HydrophobicContact CG-CG2 3.81Å; W402-I406 HydrophobicContact CZ2-CD1 4.32Å; W402-I406 WeakPolarHBondContact O-CG1 3.11Å; W402-I406 PolarHBondContact O-N 3.02Å; F403-I406 PolarHBondContact O-N 3.4Å; I406-V409 PolarHBondContact O-N 3.48Å; I406-S410 VanDerWaalsContact O-CB 3.32Å; I406-S410 WeakPolarHBondContact O-CB 3.36Å; I406-S410 PolarHBondContact O-N 2.92Å
407	F	76.8	Confident	76.4	Confident	0 Å²	0	55.3 Å²	55.3	0%	0	28%	0.276	C	S	.	.	H	α-helix	trans	-61.4	-47.5	177	169.5	-95.5	0	0	0	110.7	A136 S139 A143 K277 I278 A281 F403 D404 V405 S410 A411	A136-F407 HydrophobicContact CB-CB 4.21Å; S139-F407 WeakPolarHBondContact O-CE2 3.25Å; S139-F407 WeakPolarHBondContact OG-CE2 3.28Å; A143-F407 HydrophobicContact CB-CE2 4.03Å; A143-F407 HydrophobicContact CB-CZ 3.99Å; K277-F407 HydrophobicContact CB-CZ 4.43Å; K277-F407 HydrophobicContact CD-CE1 4.29Å; K277-F407 HydrophobicContact CD-CE2 4.08Å; K277-F407 HydrophobicContact CD-CZ 3.71Å; K277-F407 HydrophobicContact CG-CE1 4Å; K277-F407 HydrophobicContact CG-CZ 3.86Å; I278-F407 HydrophobicContact CG1-CE1 3.95Å; I278-F407 HydrophobicContact CG1-CZ 4.21Å; A281-F407 HydrophobicContact CB-CD1 4.05Å; A281-F407 HydrophobicContact CB-CE1 4.35Å; F403-F407 HydrophobicContact CE1-CB 4.29Å; F403-F407 WeakPolarHBondContact O-CB 3.23Å; F403-F407 PolarHBondContact O-N 3.4Å; D404-F407 PolarHBondContact O-N 2.94Å; V405-F407 VanDerWaalsContact C-N 3.3Å; V405-F407 PolarHBondContact O-N 3.27Å; F407-S410 PolarHBondContact O-N 2.9Å; F407-A411 WeakPolarHBondContact O-CB 3.35Å; F407-A411 PolarHBondContact O-N 2.84Å
408	L	81.4	Confident	77	Confident	27 Å²	27	52.2 Å²	52.2	14%	0.141	26%	0.259	C	S	.	.	H	α-helix	trans	-64.5	-46.3	179.7	-174.4	65.1	0	0	0	111.4	I278 I285 D404 V405 S410 A411 L412	I278-L408 HydrophobicContact CG2-CD1 3.88Å; I285-L408 HydrophobicContact CD1-CB 4.25Å; I285-L408 HydrophobicContact CD1-CD2 3.77Å; D404-L408 WeakPolarHBondContact O-CB 3.22Å; D404-L408 PolarHBondContact O-N 2.85Å; V405-L408 PolarHBondContact O-N 2.99Å; L408-S410 VanDerWaalsContact C-N 3.3Å; L408-S410 PolarHBondContact O-N 3.25Å; L408-A411 PolarHBondContact O-N 3.44Å; L408-L412 HydrophobicContact CD1-CD1 4.25Å; L408-L412 HydrophobicContact CD1-CG 4.3Å; L408-L412 HydrophobicContact CG-CD1 3.99Å; L408-L412 HydrophobicContact CG-CG 4.42Å; L408-L412 WeakPolarHBondContact O-CB 3.41Å; L408-L412 VanDerWaalsContact O-CG 3.29Å; L408-L412 WeakPolarHBondContact O-CG 3.22Å; L408-L412 PolarHBondContact O-N 2.84Å
409	V	81.9	Confident	77.6	Confident	88 Å²	88	54.9 Å²	54.9	53%	0.533	27%	0.268	S	S	.	.	H	α-helix	trans	-58.4	-44.3	176.6	171.2	0	0	0	0	110.8	V405 I406 S413	V405-V409 WeakPolarHBondContact O-CG2 3.46Å; V405-V409 PolarHBondContact O-N 2.91Å; I406-V409 PolarHBondContact O-N 3.48Å; V409-S413 WeakPolarHBondContact O-CB 3.25Å; V409-S413 PolarHBondContact O-N 2.95Å; V409-S413 PolarHBondContact O-OG 3.28Å; V409-S413 VanDerWaalsContact O-OG 3.13Å
410	S	75.4	Confident	78.3	Confident	8 Å²	8	58.3 Å²	58.3	6%	0.056	29%	0.286	C	S	.	.	H	α-helix	trans	-67.3	-38.3	178.4	-168	0	0	0	0	113.5	L137 I406 F407 L408 S413 S414	L137-S410 WeakPolarHBondContact CA-OG 3.38Å; L137-S410 PolarHBondContact O-OG 3.08Å; I406-S410 VanDerWaalsContact O-CB 3.32Å; I406-S410 WeakPolarHBondContact O-CB 3.36Å; I406-S410 PolarHBondContact O-N 2.92Å; F407-S410 PolarHBondContact O-N 2.9Å; L408-S410 VanDerWaalsContact C-N 3.3Å; L408-S410 PolarHBondContact O-N 3.25Å; S410-S413 WeakPolarHBondContact CA-OG 3.47Å; S410-S413 PolarHBondContact O-OG 3.41Å; S410-S414 VanDerWaalsContact O-CB 3.31Å; S410-S414 WeakPolarHBondContact O-CB 3.41Å; S410-S414 PolarHBondContact O-N 3.2Å; S410-S414 VanDerWaalsContact O-N 3.07Å; S410-S414 PolarHBondContact O-OG 3.41Å
411	A	73.2	Confident	78.7	Confident	0 Å²	0	57.8 Å²	57.8	0%	0	29%	0.29	C	S	.	.	H	α-helix	trans	-67.3	-47	177.8	0	0	0	0	0	110.4	V144 I278 F407 L408 S413 S414 I415	V144-A411 HydrophobicContact CG2-CB 4.15Å; V144-A411 WeakPolarHBondContact CG2-O 3.45Å; I278-A411 HydrophobicContact CD1-CB 4.07Å; I278-A411 HydrophobicContact CG1-CB 4.23Å; F407-A411 WeakPolarHBondContact O-CB 3.35Å; F407-A411 PolarHBondContact O-N 2.84Å; L408-A411 PolarHBondContact O-N 3.44Å; A411-S413 PolarHBondContact O-N 3.41Å; A411-S414 PolarHBondContact O-N 3.37Å; A411-I415 VanDerWaalsContact O-CG1 3.29Å; A411-I415 WeakPolarHBondContact O-CG1 3.27Å; A411-I415 PolarHBondContact O-N 3.49Å
412	L	86.4	Confident	78.8	Confident	95 Å²	95	55.8 Å²	55.8	50%	0.497	29%	0.286	S	S	.	.	H	α-helix	trans	-63.3	-42.5	178.6	-68.4	174.7	0	0	0	112.3	L408 S414 I415 L416	L408-L412 HydrophobicContact CD1-CD1 4.25Å; L408-L412 HydrophobicContact CD1-CG 4.3Å; L408-L412 HydrophobicContact CG-CD1 3.99Å; L408-L412 HydrophobicContact CG-CG 4.42Å; L408-L412 WeakPolarHBondContact O-CB 3.41Å; L408-L412 VanDerWaalsContact O-CG 3.29Å; L408-L412 WeakPolarHBondContact O-CG 3.22Å; L408-L412 PolarHBondContact O-N 2.84Å; L412-S414 VanDerWaalsContact C-N 3.33Å; L412-S414 PolarHBondContact O-N 3.44Å; L412-I415 PolarHBondContact O-N 2.94Å; L412-L416 WeakPolarHBondContact O-CB 3.46Å; L412-L416 PolarHBondContact O-N 2.95Å
413	S	81.5	Confident	78.9	Confident	63 Å²	63	59.2 Å²	59.2	44%	0.441	30%	0.303	S	S	.	.	H	α-helix	trans	-65.2	-36.9	176.3	66.8	0	0	0	0	112.2	V409 S410 A411 L416 F417	V409-S413 WeakPolarHBondContact O-CB 3.25Å; V409-S413 PolarHBondContact O-N 2.95Å; V409-S413 PolarHBondContact O-OG 3.28Å; V409-S413 VanDerWaalsContact O-OG 3.13Å; S410-S413 WeakPolarHBondContact CA-OG 3.47Å; S410-S413 PolarHBondContact O-OG 3.41Å; A411-S413 PolarHBondContact O-N 3.41Å; S413-L416 PolarHBondContact O-N 3.43Å; S413-F417 WeakPolarHBondContact O-CB 3.42Å; S413-F417 PolarHBondContact O-N 2.9Å
414	S	76.8	Confident	78.4	Confident	11 Å²	11	66.3 Å²	66.3	8%	0.077	34%	0.336	C	S	.	.	H	α-helix	trans	-68.8	-39.9	175.8	-58.3	0	0	0	0	112.3	S410 A411 L412 F417 L418	S410-S414 VanDerWaalsContact O-CB 3.31Å; S410-S414 WeakPolarHBondContact O-CB 3.41Å; S410-S414 PolarHBondContact O-N 3.2Å; S410-S414 VanDerWaalsContact O-N 3.07Å; S410-S414 PolarHBondContact O-OG 3.41Å; A411-S414 PolarHBondContact O-N 3.37Å; L412-S414 VanDerWaalsContact C-N 3.33Å; L412-S414 PolarHBondContact O-N 3.44Å; S414-F417 PolarHBondContact O-N 3.42Å; S414-L418 WeakPolarHBondContact O-CG 3.43Å; S414-L418 PolarHBondContact O-N 3.04Å
415	I	84.1	Confident	77.5	Confident	79 Å²	79	67.4 Å²	67.4	41%	0.405	35%	0.347	S	S	.	.	H	α-helix	trans	-61.1	-47.3	173.3	-69.4	162.8	0	0	0	109.8	V144 A411 L412 F417 L418 Y419	V144-I415 HydrophobicContact CB-CG1 4.36Å; V144-I415 HydrophobicContact CG1-CB 4.5Å; V144-I415 HydrophobicContact CG1-CG1 3.64Å; V144-I415 HydrophobicContact CG2-CD1 4.2Å; V144-I415 HydrophobicContact CG2-CG1 3.71Å; A411-I415 VanDerWaalsContact O-CG1 3.29Å; A411-I415 WeakPolarHBondContact O-CG1 3.27Å; A411-I415 PolarHBondContact O-N 3.49Å; L412-I415 PolarHBondContact O-N 2.94Å; I415-F417 PolarHBondContact O-N 2.86Å; I415-L418 PolarHBondContact O-N 3.41Å; I415-Y419 VanDerWaalsContact O-CB 3.26Å; I415-Y419 WeakPolarHBondContact O-CB 3.25Å; I415-Y419 PolarHBondContact O-N 3.25Å
416	L	84.7	Confident	76.2	Confident	101 Å²	101	68.8 Å²	68.8	53%	0.529	36%	0.357	S	S	.	.	H	α-helix	trans	-60.9	-45.3	177.9	179.9	63.9	0	0	0	111.5	L412 S413 Y419 L420	L412-L416 WeakPolarHBondContact O-CB 3.46Å; L412-L416 PolarHBondContact O-N 2.95Å; S413-L416 PolarHBondContact O-N 3.43Å; L416-Y419 PolarHBondContact O-N 3.09Å; L416-L420 HydrophobicContact CD1-CD1 4.29Å; L416-L420 HydrophobicContact CD1-CG 4.31Å; L416-L420 HydrophobicContact CG-CD1 4.18Å; L416-L420 VanDerWaalsContact O-CG 3.31Å; L416-L420 WeakPolarHBondContact O-CG 3.04Å; L416-L420 PolarHBondContact O-N 2.99Å
417	F	82.6	Confident	74.7	Confident	136 Å²	136	73.8 Å²	73.8	60%	0.596	38%	0.379	S	S	*	.	H	α-helix	trans	-60	-49.3	177.9	176.5	-96.9	0	0	0	111.8	S413 S414 I415 Y419 L420 A421	S413-F417 WeakPolarHBondContact O-CB 3.42Å; S413-F417 PolarHBondContact O-N 2.9Å; S414-F417 PolarHBondContact O-N 3.42Å; I415-F417 PolarHBondContact O-N 2.86Å; F417-Y419 VanDerWaalsContact C-N 3.33Å; F417-Y419 PolarHBondContact O-N 3.33Å; F417-L420 PolarHBondContact O-N 3.11Å; F417-A421 WeakPolarHBondContact O-CB 3.39Å; F417-A421 PolarHBondContact O-N 3.19Å
418	L	79.1	Confident	73.2	Confident	28 Å²	28	82 Å²	82	15%	0.147	42%	0.415	C	S	.	.	H	α-helix	trans	-65.4	-37.1	178.2	-71.5	176.9	0	0	0	112	V144 Y148 S414 I415 A421 H422	V144-L418 HydrophobicContact CG1-CD1 3.7Å; Y148-L418 HydrophobicContact CD1-CD1 4.25Å; Y148-L418 HydrophobicContact CD1-CD2 4.03Å; Y148-L418 HydrophobicContact CD2-CD1 4.18Å; Y148-L418 HydrophobicContact CE1-CD2 3.93Å; Y148-L418 HydrophobicContact CG-CD1 3.9Å; Y148-L418 HydrophobicContact CG-CD2 4.4Å; S414-L418 WeakPolarHBondContact O-CG 3.43Å; S414-L418 PolarHBondContact O-N 3.04Å; I415-L418 PolarHBondContact O-N 3.41Å; L418-A421 PolarHBondContact O-N 2.86Å; L418-H422 VanDerWaalsContact O-CB 3.23Å; L418-H422 WeakPolarHBondContact O-CB 3.4Å; L418-H422 PolarHBondContact O-N 2.91Å
419	Y	81.9	Confident	71	Confident	150 Å²	150	90.2 Å²	90.2	59%	0.588	45%	0.453	S	S	*	.	H	α-helix	trans	-61.7	-45.1	174.7	176.2	-101.6	0	0	0	111.9	I415 L416 F417 H422 K423	I415-Y419 VanDerWaalsContact O-CB 3.26Å; I415-Y419 WeakPolarHBondContact O-CB 3.25Å; I415-Y419 PolarHBondContact O-N 3.25Å; L416-Y419 PolarHBondContact O-N 3.09Å; F417-Y419 VanDerWaalsContact C-N 3.33Å; F417-Y419 PolarHBondContact O-N 3.33Å; Y419-H422 PolarHBondContact O-N 2.89Å; Y419-K423 WeakPolarHBondContact O-CB 3.44Å; Y419-K423 PolarHBondContact O-N 3.42Å
420	L	81.7	Confident	68.9	Low	82 Å²	82	93.6 Å²	93.6	43%	0.429	46%	0.464	S	S	.	.	H	α-helix	trans	-66.5	-43.1	176.1	-68.8	175	0	0	0	111.9	L416 F417 H422 K423 Q424	L416-L420 HydrophobicContact CD1-CD1 4.29Å; L416-L420 HydrophobicContact CD1-CG 4.31Å; L416-L420 HydrophobicContact CG-CD1 4.18Å; L416-L420 VanDerWaalsContact O-CG 3.31Å; L416-L420 WeakPolarHBondContact O-CG 3.04Å; L416-L420 PolarHBondContact O-N 2.99Å; F417-L420 PolarHBondContact O-N 3.11Å; L420-H422 VanDerWaalsContact C-N 3.32Å; L420-H422 PolarHBondContact O-N 3.14Å; L420-K423 PolarHBondContact O-N 2.92Å; L420-Q424 WeakPolarHBondContact O-CG 3.36Å; L420-Q424 PolarHBondContact O-N 2.74Å
421	A	77.8	Confident	66.7	Low	37 Å²	37	97.5 Å²	97.5	31%	0.306	50%	0.497	S	S	.	.	H	α-helix	trans	-62.5	-40.1	176.9	0	0	0	0	0	111.6	F417 L418 Q424 A425	F417-A421 WeakPolarHBondContact O-CB 3.39Å; F417-A421 PolarHBondContact O-N 3.19Å; L418-A421 PolarHBondContact O-N 2.86Å; A421-Q424 PolarHBondContact O-N 3.39Å; A421-A425 PolarHBondContact O-N 3.27Å
422	H	74.9	Confident	65	Low	74 Å²	74	107 Å²	107	34%	0.343	56%	0.559	S	S	.	*	H	α-helix	trans	-68.8	-36.1	177	-159.7	73.5	0	0	0	112.1	L418 Y419 L420 Q424 A425	L418-H422 VanDerWaalsContact O-CB 3.23Å; L418-H422 WeakPolarHBondContact O-CB 3.4Å; L418-H422 PolarHBondContact O-N 2.91Å; Y419-H422 PolarHBondContact O-N 2.89Å; L420-H422 VanDerWaalsContact C-N 3.32Å; L420-H422 PolarHBondContact O-N 3.14Å; H422-Q424 VanDerWaalsContact C-N 3.31Å; H422-Q424 PolarHBondContact O-N 3.2Å; H422-A425 WeakPolarHBondContact O-CB 3.26Å; H422-A425 PolarHBondContact O-N 3.34Å
423	K	73.9	Confident	63.9	Low	161 Å²	161	107.7 Å²	107.7	70%	0.7	56%	0.562	S	S	*	*	H	α-helix	trans	-68.1	-29.8	173.5	-170.2	178.7	179.1	-177.9	0	112.9	Y419 L420	Y419-K423 WeakPolarHBondContact O-CB 3.44Å; Y419-K423 PolarHBondContact O-N 3.42Å; L420-K423 PolarHBondContact O-N 2.92Å
424	Q	63	Low	63	Low	164 Å²	164	110 Å²	110	77%	0.766	57%	0.569	S	S	*	*	H	α-helix	trans	-80.9	-22.7	176.3	-73.7	178.4	-7.8	0	0	112.9	L420 A421 H422 P426	L420-Q424 WeakPolarHBondContact O-CG 3.36Å; L420-Q424 PolarHBondContact O-N 2.74Å; A421-Q424 PolarHBondContact O-N 3.39Å; H422-Q424 VanDerWaalsContact C-N 3.31Å; H422-Q424 PolarHBondContact O-N 3.2Å; Q424-P426 WeakPolarHBondContact O-CD 3.41Å
425	A	55.9	Low	62.2	Low	34 Å²	34	115.5 Å²	115.5	28%	0.281	60%	0.596	S	S	.	*	S	Bend	trans	-63.1	122.2	166.1	0	0	0	0	0	107.3	A421 H422 E427	A421-A425 PolarHBondContact O-N 3.27Å; H422-A425 WeakPolarHBondContact O-CB 3.26Å; H422-A425 PolarHBondContact O-N 3.34Å; A425-E427 VanDerWaalsContact C-N 3.27Å; A425-E427 PolarHBondContact O-N 3.32Å
426	P	50	Low	60.9	Low	78 Å²	78	117.6 Å²	117.6	51%	0.506	61%	0.607	S	S	.	*			trans	-69.7	86	-173.2	26.6	-32.5	0	0	0	109.8	Q424 K428	Q424-P426 WeakPolarHBondContact O-CD 3.41Å; P426-K428 PolarHBondContact O-N 2.84Å
427	E	45.7	Very low	59.4	Low	133 Å²	133	118.7 Å²	118.7	62%	0.621	61%	0.612	S	S	*	*			trans	-71.3	106.7	158.8	-79.5	-157.3	135.2	0	0	107.9	A425	A425-E427 VanDerWaalsContact C-N 3.27Å; A425-E427 PolarHBondContact O-N 3.32Å
428	K	45	Very low	57.9	Low	174 Å²	174	117.5 Å²	117.5	76%	0.757	61%	0.613	S	S	*	*			trans	58.3	82.3	152.9	-61.9	177.2	178.9	175.5	0	116.2	P426	P426-K428 PolarHBondContact O-N 2.84Å
429	Q	35.5	Very low	56.4	Low	199 Å²	199	123.9 Å²	123.9	93%	0.93	65%	0.647	S	S	*	*			trans	-102.6	65	134.8	-75.6	-174.6	-17.2	0	0	109.3
430	M	38.5	Very low	54.4	Low	158 Å²	158	121.9 Å²	121.9	78%	0.778	65%	0.651	S	S	*	*			trans	-145.4	107.6	159	-65.1	-176.4	-172.4	0	0	103.1
431	A	29.3	Very low	52.1	Low	90 Å²	90	125.3 Å²	125.3	74%	0.744	67%	0.67	S	S	*	*			cis	-153	171.6	26.6	0	0	0	0	0	110
432	P	36	Very low	49.8	Very low	201 Å²	201	133.3 Å²	133.3	100%	1.305	70%	0.703	S	S	*	*			trans	-64.9	0	149.7	29.8	-32.7	0	0	0	112.3

Retrieved 432 of 432 residues in 428.1 ms (Link to these results)

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