X5DP66_HUMAN Loading...

DiGeorge syndrome critical region 6 isoform A

AlphaFold DB , UniProt , Accession X5DP66, Species HUMAN (Homo sapiens, Human), Gene DGCR6, Length 31 aa.

						>X5DP66_HUMAN|X5DP66|DGCR6
MERSRAPWRRWRTVPGSRSDTTSCCRRYRAW
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	48.7	Very low	59.9	Low	243 Å²	243	183.4 Å²	183.4	100%	1.197	83%	0.826	S	S	*	*				0	95.3	0	-67.9	175.9	-164.1	0	0	108.1
2	E	41.5	Very low	60.7	Low	187 Å²	187	186.8 Å²	186.8	87%	0.874	83%	0.828	S	S	*	*			trans	-143.9	102.4	164.4	-95.7	-168.1	94.9	0	0	110.6
3	R	55.1	Low	61.2	Low	167 Å²	167	181.9 Å²	181.9	63%	0.63	82%	0.822	S	S	*	*			trans	63.2	69.9	130.1	-140.1	169.8	-159.3	175.1	7.1	116.3	R5	R3-R5 HydrophobicContact CG-CG 3.72Å; R3-R5 HydrophobicContact CG-CB 4.08Å; R3-R5 PolarHBondContact O-N 2.8Å; R3-R5 VanDerWaalsContact NH2-NH1 3.11Å; R3-R5 VanDerWaalsContact NH2-NH2 3.18Å
4	S	49	Very low	61.9	Low	127 Å²	127	175.5 Å²	175.5	89%	0.888	80%	0.803	S	S	*	*			trans	-57.9	57.6	144.5	-55.6	0	0	0	0	111.8	A6	S4-A6 PolarHBondContact O-N 3.05Å
5	R	61	Low	61.9	Low	178 Å²	178	172.5 Å²	172.5	67%	0.672	81%	0.806	S	S	*	*			trans	-81.1	74.2	160.4	-88.3	-176.8	173	-170.9	-5.1	106.5	R3 P7	R3-R5 HydrophobicContact CG-CG 3.72Å; R3-R5 HydrophobicContact CG-CB 4.08Å; R3-R5 PolarHBondContact O-N 2.8Å; R3-R5 VanDerWaalsContact NH2-NH1 3.11Å; R3-R5 VanDerWaalsContact NH2-NH2 3.18Å; R5-P7 WeakPolarHBondContact O-CD 3.37Å; R5-P7 VanDerWaalsContact O-N 3.12Å
6	A	61.7	Low	62	Low	64 Å²	64	166.9 Å²	166.9	53%	0.529	81%	0.809	S	S	.	*			trans	-48.6	122.1	150.9	0	0	0	0	0	105.7	S4 W8	S4-A6 PolarHBondContact O-N 3.05Å; A6-W8 PolarHBondContact O-N 2.89Å
7	P	64.6	Low	62	Low	118 Å²	118	161.3 Å²	161.3	77%	0.766	79%	0.791	S	S	*	*			trans	-65	97.8	169.9	26.8	-29.6	0	0	0	104.1	R5 R9	R5-P7 WeakPolarHBondContact O-CD 3.37Å; R5-P7 VanDerWaalsContact O-N 3.12Å; P7-R9 VanDerWaalsContact C-N 3.33Å; P7-R9 PolarHBondContact O-N 2.72Å
8	W	69.1	Low	62.2	Low	227 Å²	227	164.8 Å²	164.8	86%	0.86	79%	0.794	S	S	*	*			trans	-47.2	110.5	165.5	-59.7	90.2	0	0	0	104.5	A6 R10	A6-W8 PolarHBondContact O-N 2.89Å; W8-R10 PolarHBondContact O-N 3.13Å
9	R	67.7	Low	62.2	Low	229 Å²	229	160.8 Å²	160.8	86%	0.864	79%	0.785	S	S	*	*			trans	-56.3	98.8	173.9	-95.4	-175	172.7	-140.9	0.3	104.1	P7 W11	P7-R9 VanDerWaalsContact C-N 3.33Å; P7-R9 PolarHBondContact O-N 2.72Å; R9-W11 PolarHBondContact O-N 3.05Å
10	R	68.4	Low	62.1	Low	229 Å²	229	157.2 Å²	157.2	86%	0.864	77%	0.769	S	S	*	*			trans	-63.7	108.4	175.5	-81.1	-169.6	170.8	-178.5	-2.4	104.6	W8 R12	W8-R10 PolarHBondContact O-N 3.13Å; R10-R12 PolarHBondContact O-N 2.93Å
11	W	71.9	Confident	61.9	Low	248 Å²	248	154 Å²	154	94%	0.939	76%	0.759	S	S	*	*			trans	-55.5	107.3	169.1	-61.5	98.2	0	0	0	106.7	R9	R9-W11 PolarHBondContact O-N 3.05Å
12	R	69.3	Low	62.4	Low	225 Å²	225	145.8 Å²	145.8	85%	0.849	72%	0.722	S	S	*	*			trans	-85.2	115.5	168.1	-68.5	-172	-171.9	-163.6	3.1	105.6	R10 V14	R10-R12 PolarHBondContact O-N 2.93Å; R12-V14 PolarHBondContact O-N 2.93Å
13	T	67.3	Low	63.1	Low	123 Å²	123	140.3 Å²	140.3	76%	0.755	71%	0.705	S	S	*	*			trans	-59.3	112.3	165.9	-51.4	0	0	0	0	106.9	P15	T13-P15 WeakPolarHBondContact O-CD 3.43Å
14	V	71.3	Confident	63.3	Low	92 Å²	92	136.4 Å²	136.4	56%	0.558	70%	0.702	S	S	*	*			trans	-67.4	121.4	176.5	179.2	0	0	0	0	107	R12 G16 S17	R12-V14 PolarHBondContact O-N 2.93Å; V14-G16 PolarHBondContact O-N 2.7Å; V14-G16 VanDerWaalsContact O-N 3.13Å; V14-S17 WeakPolarHBondContact O-CB 3.43Å; V14-S17 PolarHBondContact O-N 2.91Å
15	P	62.3	Low	63.9	Low	131 Å²	131	134.4 Å²	134.4	85%	0.851	69%	0.687	S	S	*	*	T	Hydrogen-bonded Turn	trans	-62.3	119.6	175.8	24.9	-31	0	0	0	108.2	T13	T13-P15 WeakPolarHBondContact O-CD 3.43Å
16	G	62.8	Low	64.1	Low	82 Å²	82	135.1 Å²	135.1	85%	0.845	69%	0.69	S	S	*	*	T	Hydrogen-bonded Turn	trans	107.9	-11.9	-169.9	0	0	0	0	0	114.7	V14 R18	V14-G16 PolarHBondContact O-N 2.7Å; V14-G16 VanDerWaalsContact O-N 3.13Å; G16-R18 PolarHBondContact O-N 2.78Å
17	S	62.3	Low	63.9	Low	72 Å²	72	142.5 Å²	142.5	50%	0.503	70%	0.704	S	S	.	*			trans	-74.3	79.3	159.7	-80.4	0	0	0	0	108.8	V14 S19	V14-S17 WeakPolarHBondContact O-CB 3.43Å; V14-S17 PolarHBondContact O-N 2.91Å; S17-S19 PolarHBondContact O-N 2.82Å
18	R	65.1	Low	63.9	Low	225 Å²	225	146.2 Å²	146.2	85%	0.849	70%	0.704	S	S	*	*			trans	-64.3	91.7	155.2	-174.5	170.2	174.2	168.3	-3.1	105	G16 D20	G16-R18 PolarHBondContact O-N 2.78Å; R18-D20 VanDerWaalsContact C-N 3.28Å; R18-D20 PolarHBondContact O-N 2.88Å
19	S	62.1	Low	63.6	Low	88 Å²	88	146.4 Å²	146.4	62%	0.615	71%	0.705	S	S	*	*			trans	-52.8	103.6	166.2	-65.4	0	0	0	0	105.5	S17 T21	S17-S19 PolarHBondContact O-N 2.82Å; S19-T21 PolarHBondContact O-N 2.72Å
20	D	60.1	Low	63	Low	88 Å²	88	139.2 Å²	139.2	47%	0.471	69%	0.694	S	S	.	*			trans	-69.7	75.3	169.6	-165.2	-91.8	0	0	0	106.1	R18 T22 S23 C24	R18-D20 VanDerWaalsContact C-N 3.28Å; R18-D20 PolarHBondContact O-N 2.88Å; D20-T22 VanDerWaalsContact O-N 3.16Å; D20-T22 PolarHBondContact O-N 3.38Å; D20-S23 PolarHBondContact O-N 3.39Å; D20-S23 WeakPolarHBondContact OD1-CA 3.14Å; D20-S23 WeakPolarHBondContact OD1-CB 3.47Å; D20-S23 PolarHBondContact OD1-N 3.04Å; D20-C24 PolarHBondContact O-N 2.73Å
21	T	58.7	Low	62.4	Low	92 Å²	92	143.4 Å²	143.4	56%	0.564	71%	0.71	S	S	*	*	H	α-helix	trans	-57.8	-25	175.7	45.1	0	0	0	0	109.6	S19 C24 C25	S19-T21 PolarHBondContact O-N 2.72Å; T21-C24 PolarHBondContact O-N 3.16Å; T21-C25 PolarHBondContact O-N 3.45Å; T21-C25 PolarHBondContact O-SG 3.11Å
22	T	58.3	Low	62	Low	69 Å²	69	138.2 Å²	138.2	42%	0.423	70%	0.699	S	S	.	*	H	α-helix	trans	-59.2	-44.1	171.7	-53.3	0	0	0	0	112.9	D20 C25 R26	D20-T22 VanDerWaalsContact O-N 3.16Å; D20-T22 PolarHBondContact O-N 3.38Å; T22-C25 PolarHBondContact O-N 3.33Å; T22-R26 WeakPolarHBondContact O-CG 3.4Å; T22-R26 VanDerWaalsContact O-N 3.11Å; T22-R26 PolarHBondContact O-N 3.29Å
23	S	56.7	Low	61.6	Low	72 Å²	72	133.6 Å²	133.6	50%	0.503	69%	0.691	S	S	.	*	H	α-helix	trans	-71.6	-30.4	177.5	-169.2	0	0	0	0	112.7	D20	D20-S23 PolarHBondContact O-N 3.39Å; D20-S23 WeakPolarHBondContact OD1-CA 3.14Å; D20-S23 WeakPolarHBondContact OD1-CB 3.47Å; D20-S23 PolarHBondContact OD1-N 3.04Å
24	C	60.3	Low	61.3	Low	86 Å²	86	134.2 Å²	134.2	58%	0.581	69%	0.687	S	S	*	*	H	α-helix	trans	-65.1	-49.6	170.3	-98.1	0	0	0	0	110.9	D20 T21 R26 R27 Y28	D20-C24 PolarHBondContact O-N 2.73Å; T21-C24 PolarHBondContact O-N 3.16Å; C24-R26 PolarHBondContact O-N 3.2Å; C24-R27 PolarHBondContact O-N 2.97Å; C24-Y28 VanDerWaalsContact O-CD2 3.26Å; C24-Y28 WeakPolarHBondContact O-CD2 3.26Å
25	C	61.9	Low	60.7	Low	85 Å²	85	136.7 Å²	136.7	57%	0.574	70%	0.695	S	S	*	*	H	α-helix	trans	-68.7	-29.6	-174.8	-64.7	0	0	0	0	113.6	T21 T22 R27 Y28	T21-C25 PolarHBondContact O-N 3.45Å; T21-C25 PolarHBondContact O-SG 3.11Å; T22-C25 PolarHBondContact O-N 3.33Å; C25-R27 VanDerWaalsContact C-N 3.28Å; C25-R27 PolarHBondContact O-N 3.5Å; C25-Y28 PolarHBondContact O-N 3.35Å
26	R	63.6	Low	60.6	Low	193 Å²	193	137.1 Å²	137.1	73%	0.728	69%	0.685	S	S	*	*	H	α-helix	trans	-66.8	-24.6	178.8	-76.1	-174.5	-157.8	179.7	8.7	113.9	T22 C24 Y28	T22-R26 WeakPolarHBondContact O-CG 3.4Å; T22-R26 VanDerWaalsContact O-N 3.11Å; T22-R26 PolarHBondContact O-N 3.29Å; C24-R26 PolarHBondContact O-N 3.2Å; R26-Y28 VanDerWaalsContact C-N 3.31Å; R26-Y28 PolarHBondContact O-N 3.41Å
27	R	58.4	Low	60.4	Low	219 Å²	219	140.7 Å²	140.7	83%	0.826	68%	0.675	S	S	*	*	T	Hydrogen-bonded Turn	trans	-76.7	-14.5	177.4	-79.3	-174.4	175.7	-174.6	-1.4	114.1	C24 C25	C24-R27 PolarHBondContact O-N 2.97Å; C25-R27 VanDerWaalsContact C-N 3.28Å; C25-R27 PolarHBondContact O-N 3.5Å
28	Y	65	Low	60.3	Low	195 Å²	195	145.6 Å²	145.6	77%	0.765	69%	0.687	S	S	*	*	T	Hydrogen-bonded Turn	trans	-105.8	5.6	-178.7	-64.7	-82.7	0	0	0	113.9	C24 C25 R26	C24-Y28 VanDerWaalsContact O-CD2 3.26Å; C24-Y28 WeakPolarHBondContact O-CD2 3.26Å; C25-Y28 PolarHBondContact O-N 3.35Å; R26-Y28 VanDerWaalsContact C-N 3.31Å; R26-Y28 PolarHBondContact O-N 3.41Å
29	R	61.5	Low	59.9	Low	232 Å²	232	139.5 Å²	139.5	88%	0.875	67%	0.674	S	S	*	*	S	Bend	trans	-109.7	56.7	171.2	-164.6	-179.9	176.3	146.3	-1.3	110.3
30	A	56	Low	59.7	Low	77 Å²	77	143.8 Å²	143.8	64%	0.636	68%	0.679	S	S	*	*			trans	-142.4	-6	168	0	0	0	0	0	113.9
31	W	56.3	Low	59.7	Low	318 Å²	318	148.9 Å²	148.9	100%	1.205	70%	0.698	S	S	*	*			trans	-157	0	163.9	-81.3	88.8	0	0	0	108.7

Retrieved 31 of 31 residues in 10.2 ms (Link to these results)

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