X5DPB4_HUMAN Loading...

Ribosomal protein S6 kinase 90kDa polypeptide 2 isoform A

AlphaFold DB , UniProt , Accession X5DPB4, Species HUMAN (Homo sapiens, Human), Gene RPS6KA2, Length 19 aa.

						>X5DPB4_HUMAN|X5DPB4|RPS6KA2
MPIAQLWNYGKRSRWSLWK
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	51.1	Low	66.9	Low	223 Å²	223	124.7 Å²	124.7	100%	1.099	64%	0.639	S	S	*	*				0	90.5	0	-80.3	163.7	155.9	0	0	109.8
2	P	57.9	Low	66.8	Low	87 Å²	87	130.5 Å²	130.5	57%	0.565	65%	0.646	S	S	*	*			trans	-86	-12.3	-175.1	31.3	-32.3	0	0	0	115	A4 Q5 L6	P2-A4 PolarHBondContact O-N 3.41Å; P2-Q5 PolarHBondContact O-N 3.01Å; P2-L6 PolarHBondContact O-N 3.38Å
3	I	67.5	Low	66.8	Low	139 Å²	139	125.9 Å²	125.9	71%	0.713	64%	0.635	S	S	*	*	H	α-helix	trans	-63.8	-35.7	-177.8	-79.9	136.1	0	0	0	113.2	Q5 L6 W7	I3-Q5 VanDerWaalsContact C-N 3.3Å; I3-Q5 PolarHBondContact O-N 3.39Å; I3-L6 PolarHBondContact O-N 3.41Å; I3-W7 PolarHBondContact O-N 3.36Å
4	A	64.7	Low	66.9	Low	74 Å²	74	129.4 Å²	129.4	61%	0.612	64%	0.636	S	S	*	*	H	α-helix	trans	-65.9	-31.7	-179.6	0	0	0	0	0	112.9	P2	P2-A4 PolarHBondContact O-N 3.41Å
5	Q	69.8	Low	67	Low	126 Å²	126	134.7 Å²	134.7	59%	0.589	65%	0.647	S	S	*	*	H	α-helix	trans	-73.7	-46.6	177.4	-79.2	176.8	-59.3	0	0	111.2	P2 I3 W7 N8 Y9	P2-Q5 PolarHBondContact O-N 3.01Å; I3-Q5 VanDerWaalsContact C-N 3.3Å; I3-Q5 PolarHBondContact O-N 3.39Å; Q5-W7 VanDerWaalsContact C-N 3.31Å; Q5-W7 PolarHBondContact O-N 3.4Å; Q5-N8 WeakPolarHBondContact O-CB 3.44Å; Q5-N8 PolarHBondContact O-N 3.25Å; Q5-Y9 PolarHBondContact O-N 3.44Å; Q5-Y9 WeakPolarHBondContact O-CD2 3.48Å; Q5-Y9 HydrophobicContact CB-CE2 4.33Å
6	L	69.3	Low	67.1	Low	127 Å²	127	131.8 Å²	131.8	67%	0.665	65%	0.645	S	S	*	*	H	α-helix	trans	-58.6	-40.2	-179.9	-78.9	162	0	0	0	113	P2 I3 N8 Y9 G10	P2-L6 PolarHBondContact O-N 3.38Å; I3-L6 PolarHBondContact O-N 3.41Å; L6-N8 VanDerWaalsContact C-N 3.28Å; L6-N8 PolarHBondContact O-N 3.37Å; L6-Y9 PolarHBondContact O-N 3.43Å; L6-G10 PolarHBondContact O-N 3.49Å
7	W	72.4	Confident	66.9	Low	182 Å²	182	131.8 Å²	131.8	69%	0.689	65%	0.648	S	S	*	*	H	α-helix	trans	-63	-34.7	176.6	-174.6	-101.8	0	0	0	112.8	I3 Q5 K11	I3-W7 PolarHBondContact O-N 3.36Å; Q5-W7 VanDerWaalsContact C-N 3.31Å; Q5-W7 PolarHBondContact O-N 3.4Å; W7-K11 VanDerWaalsContact O-CG 3.25Å; W7-K11 WeakPolarHBondContact O-CG 3.07Å; W7-K11 PolarHBondContact O-N 3.38Å
8	N	72.4	Confident	66.7	Low	103 Å²	103	137.2 Å²	137.2	55%	0.551	66%	0.66	S	S	*	*	H	α-helix	trans	-75.7	-34.6	-178.2	-152.9	4.2	0	0	0	112.2	Q5 L6 K11 R12	Q5-N8 WeakPolarHBondContact O-CB 3.44Å; Q5-N8 PolarHBondContact O-N 3.25Å; L6-N8 VanDerWaalsContact C-N 3.28Å; L6-N8 PolarHBondContact O-N 3.37Å; N8-K11 PolarHBondContact O-N 3.43Å; N8-R12 PolarHBondContact O-N 3.19Å; N8-R12 WeakPolarHBondContact O-CB 3.49Å; N8-R12 VanDerWaalsContact O-CB 3.28Å
9	Y	72.3	Confident	66	Low	169 Å²	169	143 Å²	143	66%	0.663	68%	0.682	S	S	*	*	H	α-helix	trans	-62.9	-47.3	174.6	-77.4	-77.5	0	0	0	112.4	Q5 L6 K11 R12 S13	Q5-Y9 PolarHBondContact O-N 3.44Å; Q5-Y9 WeakPolarHBondContact O-CD2 3.48Å; Q5-Y9 HydrophobicContact CB-CE2 4.33Å; L6-Y9 PolarHBondContact O-N 3.43Å; Y9-K11 VanDerWaalsContact C-N 3.32Å; Y9-K11 PolarHBondContact O-N 3.33Å; Y9-R12 PolarHBondContact O-N 3.48Å; Y9-S13 WeakPolarHBondContact O-CB 3.25Å; Y9-S13 PolarHBondContact O-N 3.32Å
10	G	71.4	Confident	66	Low	44 Å²	44	143 Å²	143	45%	0.454	68%	0.682	S	S	.	*	H	α-helix	trans	-65.1	-34.9	179.6	0	0	0	0	0	113.1	L6 R14	L6-G10 PolarHBondContact O-N 3.49Å; G10-R14 PolarHBondContact O-N 3.33Å
11	K	67.1	Low	66	Low	98 Å²	98	143 Å²	143	43%	0.426	68%	0.682	S	S	.	*	H	α-helix	trans	-69.5	-50.3	174.8	-70.4	-96.3	-176.8	166.7	0	111	W7 N8 Y9 S13 R14 W15	W7-K11 VanDerWaalsContact O-CG 3.25Å; W7-K11 WeakPolarHBondContact O-CG 3.07Å; W7-K11 PolarHBondContact O-N 3.38Å; N8-K11 PolarHBondContact O-N 3.43Å; Y9-K11 VanDerWaalsContact C-N 3.32Å; Y9-K11 PolarHBondContact O-N 3.33Å; K11-S13 VanDerWaalsContact C-N 3.32Å; K11-S13 PolarHBondContact O-N 2.94Å; K11-R14 VanDerWaalsContact O-N 3.09Å; K11-R14 PolarHBondContact O-N 3.38Å; K11-R14 WeakPolarHBondContact O-CB 3.28Å; K11-W15 PolarHBondContact O-N 3.38Å
12	R	65.1	Low	66.9	Low	194 Å²	194	138.6 Å²	138.6	73%	0.732	66%	0.658	S	S	*	*	H	α-helix	trans	-64	-35.3	-176.8	-166.3	164.4	-178.6	158.6	-1.6	112.9	N8 Y9 R14 W15 S16	N8-R12 PolarHBondContact O-N 3.19Å; N8-R12 WeakPolarHBondContact O-CB 3.49Å; N8-R12 VanDerWaalsContact O-CB 3.28Å; Y9-R12 PolarHBondContact O-N 3.48Å; R12-R14 VanDerWaalsContact C-N 3.31Å; R12-R14 PolarHBondContact O-N 3.48Å; R12-W15 PolarHBondContact O-N 3.05Å; R12-S16 PolarHBondContact O-N 3.49Å
13	S	67.7	Low	67.4	Low	71 Å²	71	141.6 Å²	141.6	50%	0.497	66%	0.664	S	S	.	*	H	α-helix	trans	-65.1	-33.9	174	-167.1	0	0	0	0	112.7	Y9 K11 S16 L17	Y9-S13 WeakPolarHBondContact O-CB 3.25Å; Y9-S13 PolarHBondContact O-N 3.32Å; K11-S13 VanDerWaalsContact C-N 3.32Å; K11-S13 PolarHBondContact O-N 2.94Å; S13-S16 PolarHBondContact O-N 3.34Å; S13-L17 PolarHBondContact O-N 3.09Å
14	R	68.5	Low	67.4	Low	174 Å²	174	141.8 Å²	141.8	66%	0.657	66%	0.661	S	S	*	*	H	α-helix	trans	-71.9	-33.7	-179.9	-152	-178.1	-66.1	175.5	-3.7	112	G10 K11 R12 S16 L17 W18	G10-R14 PolarHBondContact O-N 3.33Å; K11-R14 VanDerWaalsContact O-N 3.09Å; K11-R14 PolarHBondContact O-N 3.38Å; K11-R14 WeakPolarHBondContact O-CB 3.28Å; R12-R14 VanDerWaalsContact C-N 3.31Å; R12-R14 PolarHBondContact O-N 3.48Å; R14-S16 VanDerWaalsContact C-N 3.32Å; R14-L17 PolarHBondContact O-N 3.46Å; R14-W18 VanDerWaalsContact O-CD1 3.27Å
15	W	67.5	Low	67.6	Low	210 Å²	210	146.3 Å²	146.3	80%	0.795	66%	0.664	S	S	*	*	H	α-helix	trans	-72.1	-24	174.2	-69.1	99.7	0	0	0	113.5	K11 R12	K11-W15 PolarHBondContact O-N 3.38Å; R12-W15 PolarHBondContact O-N 3.05Å
16	S	69.1	Low	67.4	Low	87 Å²	87	147.7 Å²	147.7	61%	0.608	67%	0.67	S	S	*	*	H	α-helix	trans	-82.5	-15.8	177.1	-169	0	0	0	0	113.8	R12 S13 R14	R12-S16 PolarHBondContact O-N 3.49Å; S13-S16 PolarHBondContact O-N 3.34Å; R14-S16 VanDerWaalsContact C-N 3.32Å
17	L	62.9	Low	67.3	Low	133 Å²	133	149.3 Å²	149.3	70%	0.696	67%	0.67	S	S	*	*	T	Hydrogen-bonded Turn	trans	-87.9	-9	-177.5	-122.2	146.3	0	0	0	113	S13 R14	S13-L17 PolarHBondContact O-N 3.09Å; R14-L17 PolarHBondContact O-N 3.46Å
18	W	63	Low	66.9	Low	229 Å²	229	146.6 Å²	146.6	87%	0.867	67%	0.668	S	S	*	*	T	Hydrogen-bonded Turn	trans	-112.3	12.2	178.7	-69.2	78.7	0	0	0	112.5	R14	R14-W18 VanDerWaalsContact O-CD1 3.27Å
19	K	55.1	Low	66.3	Low	247 Å²	247	150.5 Å²	150.5	100%	1.074	68%	0.679	S	S	*	*			trans	-103.1	0	158.6	-81.6	-163.2	-174.4	-174.3	0	108.2

Retrieved 19 of 19 residues in 8.6 ms (Link to these results)

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