X5DQZ7_HUMAN Loading...

Glutathione peroxidase 1 isoform A

AlphaFold DB , UniProt , Accession X5DQZ7, Species HUMAN (Homo sapiens, Human), Gene GPX1, Length 46 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M59.2Low60.6Low192 Ų19295.9 Ų95.995%0.94661%0.611SS**  0-40.70-74.1-174.3-173.700113.8R5M1-R5 PolarHBondContact O-N 3.28Å; M1-R5 WeakPolarHBondContact O-CG 3.37Å
2C60.7Low62.4Low102 Ų102104.8 Ų104.869%0.68964%0.639SS**Hα-helixtrans-62.7-48.8-178.7-120.20000114.1A4 R5 L6C2-A4 PolarHBondContact O-N 3.39Å; C2-R5 PolarHBondContact O-N 3.01Å; C2-L6 PolarHBondContact O-N 3.32Å
3A59.9Low64.6Low79 Ų79100.7 Ų100.765%0.65362%0.617SS**Hα-helixtrans-64-38.9-177.500000113.6L6 A7A3-L6 PolarHBondContact O-N 3.42Å; A3-A7 WeakPolarHBondContact O-CB 3.5Å; A3-A7 PolarHBondContact O-N 3.13Å
4A59.2Low66.8Low69 Ų6997.4 Ų97.457%0.5760%0.597SS**Hα-helixtrans-67.8-36177.300000112.5C2 A8C2-A4 PolarHBondContact O-N 3.39Å; A4-A8 WeakPolarHBondContact O-CB 3.32Å; A4-A8 PolarHBondContact O-N 2.9Å
5R60.1Low68.6Low185 Ų18595.5 Ų95.570%0.69858%0.575SS**Hα-helixtrans-67.4-40.4174.2-76.7-179.8170.4156.9-1.8111.9M1 C2 A9M1-R5 PolarHBondContact O-N 3.28Å; M1-R5 WeakPolarHBondContact O-CG 3.37Å; C2-R5 PolarHBondContact O-N 3.01Å; R5-A9 WeakPolarHBondContact O-CB 3.46Å; R5-A9 PolarHBondContact O-N 3.05Å
6L58.6Low70.2Confident123 Ų12394.3 Ų94.364%0.64458%0.578SS**Hα-helixtrans-65.8-42.6174.9-78.4155.6000112C2 A3 A9 A10C2-L6 PolarHBondContact O-N 3.32Å; A3-L6 PolarHBondContact O-N 3.42Å; L6-A9 PolarHBondContact O-N 3.35Å; L6-A10 PolarHBondContact O-N 3.45Å
7A60.9Low71.7Confident63 Ų6393.7 Ų93.752%0.52157%0.566SS.*Hα-helixtrans-64.5-41.6176.600000112.3A3 A9 A10 A11A3-A7 WeakPolarHBondContact O-CB 3.5Å; A3-A7 PolarHBondContact O-N 3.13Å; A7-A9 VanDerWaalsContact C-N 3.35Å; A7-A10 PolarHBondContact O-N 3.15Å; A7-A11 PolarHBondContact O-N 3.35Å; A7-A11 VanDerWaalsContact O-N 3.13Å
8A59.8Low73Confident49 Ų4992.7 Ų92.741%0.40556%0.564SS.*Hα-helixtrans-65.5-37.3175.200000112.3A4 A10 A11 F17A4-A8 WeakPolarHBondContact O-CB 3.32Å; A4-A8 PolarHBondContact O-N 2.9Å; A8-A10 VanDerWaalsContact C-N 3.28Å; A8-A10 PolarHBondContact O-N 3.26Å; A8-A11 PolarHBondContact O-N 3.17Å; A8-F17 HydrophobicContact CB-CE1 4.25Å; A8-F17 HydrophobicContact CB-CZ 4.35Å
9A60.4Low74.3Confident89 Ų8990.9 Ų90.974%0.73656%0.56SS**Hα-helixtrans-69.4-24.5175.700000113.3R5 L6 A7R5-A9 WeakPolarHBondContact O-CB 3.46Å; R5-A9 PolarHBondContact O-N 3.05Å; L6-A9 PolarHBondContact O-N 3.35Å; A7-A9 VanDerWaalsContact C-N 3.35Å
10A62Low75.5Confident75 Ų7595.2 Ų95.262%0.6257%0.565SS**Hα-helixtrans-87-19.817700000113.6L6 A7 A8 Q12L6-A10 PolarHBondContact O-N 3.45Å; A7-A10 PolarHBondContact O-N 3.15Å; A8-A10 VanDerWaalsContact C-N 3.28Å; A8-A10 PolarHBondContact O-N 3.26Å; A10-Q12 PolarHBondContact O-N 3.1Å
11A65.6Low76.5Confident29 Ų2993.4 Ų93.424%0.2456%0.556CS.*  trans-76.9103.8-178.400000111A7 A8 S13 A16 F17A7-A11 PolarHBondContact O-N 3.35Å; A7-A11 VanDerWaalsContact O-N 3.13Å; A8-A11 PolarHBondContact O-N 3.17Å; A11-S13 PolarHBondContact O-N 3.31Å; A11-A16 HydrophobicContact CB-CB 3.8Å; A11-F17 HydrophobicContact CB-CE2 3.57Å; A11-F17 HydrophobicContact CB-CZ 3.5Å; A11-F17 VanDerWaalsContact CB-CZ 3.5Å; A11-F17 HydrophobicContact CB-CE1 4.47Å
12Q82.8Confident78.3Confident203 Ų20393 Ų9395%0.94956%0.557SS**  trans-73.6-9.9-179.8-64.1178.1-24.400113.7A10A10-Q12 PolarHBondContact O-N 3.1Å
13S91.3Very high80.1Confident51 Ų5193.2 Ų93.236%0.35757%0.566SS.*SBendtrans-147151.9-175.3176.20000111.3A11 Y15 A16A11-S13 PolarHBondContact O-N 3.31Å; S13-Y15 PolarHBondContact O-N 3.36Å; S13-Y15 VanDerWaalsContact O-N 3.1Å; S13-Y15 VanDerWaalsContact OG-CD2 3.24Å; S13-Y15 WeakPolarHBondContact OG-CD2 3.34Å; S13-Y15 PolarHBondContact OG-N 3.03Å; S13-A16 PolarHBondContact O-N 3.27Å
14V94.1Very high81.8Confident55 Ų5591.2 Ų91.233%0.33355%0.553SS.*G310 helixtrans-57.5-21.7173.6-61.70000113.1A16 F17 L30 I40V14-A16 VanDerWaalsContact O-N 3.15Å; V14-A16 PolarHBondContact O-N 3.42Å; V14-F17 WeakPolarHBondContact O-CD2 3.37Å; V14-F17 PolarHBondContact O-N 3.04Å; V14-F17 VanDerWaalsContact O-N 3.1Å; V14-L30 HydrophobicContact CB-CD1 4.08Å; V14-L30 WeakPolarHBondContact O-CB 3.39Å; V14-I40 HydrophobicContact CG1-CD1 4.49Å
15Y94.9Very high83.5Confident69 Ų6990.4 Ų90.427%0.27155%0.551SS.*G310 helixtrans-67.6-13.1-177.5-55.6-33.3000114.9S13 F17 L30 R34S13-Y15 PolarHBondContact O-N 3.36Å; S13-Y15 VanDerWaalsContact O-N 3.1Å; S13-Y15 VanDerWaalsContact OG-CD2 3.24Å; S13-Y15 WeakPolarHBondContact OG-CD2 3.34Å; S13-Y15 PolarHBondContact OG-N 3.03Å; Y15-F17 PolarHBondContact O-N 3.3Å; Y15-L30 WeakPolarHBondContact CD1-O 3.24Å; Y15-R34 WeakPolarHBondContact OH-CA 3.49Å; Y15-R34 HydrophobicContact CE2-CB 4.31Å; Y15-R34 HydrophobicContact CE1-CB 4.35Å; Y15-R34 HydrophobicContact CE2-CG 3.96Å
16A94.5Very high85.2Confident75 Ų7589 Ų8962%0.6255%0.553SS**G310 helixtrans-79.1-6.8173.800000113.4A11 S13 V14A11-A16 HydrophobicContact CB-CB 3.8Å; S13-A16 PolarHBondContact O-N 3.27Å; V14-A16 VanDerWaalsContact O-N 3.15Å; V14-A16 PolarHBondContact O-N 3.42Å
17F94.6Very high87.1Confident85 Ų8585.6 Ų85.637%0.37354%0.538SS..  trans-110.1154.1-173.5-57.1-85.5000112.2A8 A11 V14 Y15 L30A8-F17 HydrophobicContact CB-CE1 4.25Å; A8-F17 HydrophobicContact CB-CZ 4.35Å; A11-F17 HydrophobicContact CB-CE2 3.57Å; A11-F17 HydrophobicContact CB-CZ 3.5Å; A11-F17 VanDerWaalsContact CB-CZ 3.5Å; A11-F17 HydrophobicContact CB-CE1 4.47Å; V14-F17 WeakPolarHBondContact O-CD2 3.37Å; V14-F17 PolarHBondContact O-N 3.04Å; V14-F17 VanDerWaalsContact O-N 3.1Å; Y15-F17 PolarHBondContact O-N 3.3Å; F17-L30 PolarHBondContact O-N 3.06Å; F17-L30 HydrophobicContact CB-CD1 4.25Å
18S96.3Very high88.9Confident75 Ų7586.1 Ų86.152%0.52453%0.534SS..EExtended strand (participates in β ladder)trans-134156.8169.662.10000110.5V28S18-V28 CarbonylContact C-O 3.57Å; S18-V28 WeakPolarHBondContact CA-O 3.43Å; S18-V28 VanDerWaalsContact CB-O 3.24Å; S18-V28 WeakPolarHBondContact CB-O 3.48Å
19A97Very high90.7Very high60 Ų6086.5 Ų86.550%0.49653%0.534SS..EExtended strand (participates in β ladder)trans-137.8150.3177.500000110.6P27 V28A19-P27 WeakPolarHBondContact O-CA 3.48Å; A19-V28 PolarHBondContact N-O 2.68Å; A19-V28 PolarHBondContact O-N 2.98Å
20R97.9Very high92.4Very high176 Ų17684.3 Ų84.366%0.66451%0.509SS*.  trans-81.3135.7174-73.1-175.7-165.9-82-0.8110.3G25 P27R20-G25 PolarHBondContact NH1-O 3.5Å; R20-P27 HydrophobicContact CG-CG 4.24Å
21P97.7Very high94.1Very high57 Ų5782 Ų8237%0.3749%0.494SS..  trans-60.8155.7172.3-21.933.2000112.3A23 G24 E26 V28P21-A23 VanDerWaalsContact C-N 3.26Å; P21-A23 PolarHBondContact O-N 3.1Å; P21-G24 WeakPolarHBondContact O-CA 3.38Å; P21-G24 PolarHBondContact O-N 2.97Å; P21-E26 WeakPolarHBondContact CD-O 3.39Å; P21-V28 HydrophobicContact CG-CG2 3.89Å
22L96.5Very high95.6Very high185 Ų18584.8 Ų84.897%0.96951%0.511SS*.THydrogen-bonded Turntrans-58.3-38.6176.3-179.463.7000112.3G24L22-G24 PolarHBondContact O-N 3.09Å; L22-G24 VanDerWaalsContact O-N 3.13Å
23A97.4Very high96.4Very high106 Ų10678.3 Ų78.388%0.87648%0.482SS*.THydrogen-bonded Turntrans-711.2176.200000113.8P21P21-A23 VanDerWaalsContact C-N 3.26Å; P21-A23 PolarHBondContact O-N 3.1Å
24G95.2Very high96.7Very high37 Ų3784.8 Ų84.838%0.38150%0.499SS..  trans81.8-167.5-171.700000113.2P21 L22P21-G24 WeakPolarHBondContact O-CA 3.38Å; P21-G24 PolarHBondContact O-N 2.97Å; L22-G24 PolarHBondContact O-N 3.09Å; L22-G24 VanDerWaalsContact O-N 3.13Å
25G95.3Very high96.8Very high51 Ų5185.8 Ų85.853%0.52652%0.521SS..  trans98.2-159.5176.800000115.5R20R20-G25 PolarHBondContact NH1-O 3.5Å
26E97.4Very high97Very high157 Ų15789.5 Ų89.573%0.73454%0.538SS*.SBendtrans-67.2139.8-177.5-72.5-54.212900111.7P21 V28P21-E26 WeakPolarHBondContact CD-O 3.39Å; E26-V28 PolarHBondContact O-N 3.22Å
27P98Very high97.1Very high51 Ų5193.1 Ų93.133%0.33155%0.552SS.*PPolyproline II helixtrans-59.1133.6174.4-22.834000112A19 R20A19-P27 WeakPolarHBondContact O-CA 3.48Å; R20-P27 HydrophobicContact CG-CG 4.24Å
28V97.6Very high97.3Very high74 Ų7492.2 Ų92.245%0.44855%0.551SS.*EExtended strand (participates in β ladder)trans-90.8121.1173.7179.20000108.7S18 A19 P21 E26S18-V28 CarbonylContact C-O 3.57Å; S18-V28 WeakPolarHBondContact CA-O 3.43Å; S18-V28 VanDerWaalsContact CB-O 3.24Å; S18-V28 WeakPolarHBondContact CB-O 3.48Å; A19-V28 PolarHBondContact N-O 2.68Å; A19-V28 PolarHBondContact O-N 2.98Å; P21-V28 HydrophobicContact CG-CG2 3.89Å; E26-V28 PolarHBondContact O-N 3.22Å
29S97.4Very high97.4Very high56 Ų5695.6 Ų95.639%0.39256%0.562SS.*EExtended strand (participates in β ladder)trans-73.3129.6171.8174.80000110.8G31 S32S29-G31 VanDerWaalsContact OG-N 3.09Å; S29-G31 PolarHBondContact OG-N 2.83Å; S29-G31 PolarHBondContact O-N 3.22Å; S29-S32 WeakPolarHBondContact O-CB 3.24Å; S29-S32 PolarHBondContact O-N 3.19Å; S29-S32 PolarHBondContact O-OG 3.21Å
30L97.5Very high97.4Very high43 Ų4398.5 Ų98.523%0.22557%0.568CS.*G310 helixtrans-65.8-17.9172.5-61-175.9000112V14 Y15 F17 S32 L33V14-L30 HydrophobicContact CB-CD1 4.08Å; V14-L30 WeakPolarHBondContact O-CB 3.39Å; Y15-L30 WeakPolarHBondContact CD1-O 3.24Å; F17-L30 PolarHBondContact O-N 3.06Å; F17-L30 HydrophobicContact CB-CD1 4.25Å; L30-S32 PolarHBondContact O-N 3.04Å; L30-L33 HydrophobicContact CD2-CD1 4.41Å; L30-L33 WeakPolarHBondContact O-CB 3.12Å; L30-L33 PolarHBondContact O-N 3.41Å
31G97.3Very high97.4Very high28 Ų2896.7 Ų96.729%0.28957%0.567SS.*G310 helixtrans-58.5-26.7172.700000113.7S29 L33 R34S29-G31 VanDerWaalsContact OG-N 3.09Å; S29-G31 PolarHBondContact OG-N 2.83Å; S29-G31 PolarHBondContact O-N 3.22Å; G31-L33 PolarHBondContact O-N 3Å; G31-R34 PolarHBondContact O-N 3.32Å
32S97.9Very high97.4Very high86 Ų86101.8 Ų101.860%0.60159%0.591SS**G310 helixtrans-65.1-16.6175.2650000113.9S29 L30S29-S32 WeakPolarHBondContact O-CB 3.24Å; S29-S32 PolarHBondContact O-N 3.19Å; S29-S32 PolarHBondContact O-OG 3.21Å; L30-S32 PolarHBondContact O-N 3.04Å
33L97.9Very high97.4Very high67 Ų6799 Ų9935%0.35158%0.582SS.*G310 helixtrans-9814.9-178.7-58.2175000113.1L30 G31 G35 K36 L38L30-L33 HydrophobicContact CD2-CD1 4.41Å; L30-L33 WeakPolarHBondContact O-CB 3.12Å; L30-L33 PolarHBondContact O-N 3.41Å; G31-L33 PolarHBondContact O-N 3Å; L33-G35 PolarHBondContact O-N 3.13Å; L33-K36 WeakPolarHBondContact O-CB 3.47Å; L33-K36 PolarHBondContact O-N 2.94Å; L33-L38 HydrophobicContact CB-CD1 4.1Å; L33-L38 HydrophobicContact CB-CD2 4.12Å; L33-L38 HydrophobicContact CD1-CD1 3.96Å; L33-L38 HydrophobicContact CD1-CD2 3.83Å
34R97.3Very high97.4Very high188 Ų18898.7 Ų98.771%0.70958%0.579SS**THydrogen-bonded Turntrans-55.7133.8176.3-170.3177.5-177.293.3-0.7110.9Y15 G31Y15-R34 WeakPolarHBondContact OH-CA 3.49Å; Y15-R34 HydrophobicContact CE2-CB 4.31Å; Y15-R34 HydrophobicContact CE1-CB 4.35Å; Y15-R34 HydrophobicContact CE2-CG 3.96Å; G31-R34 PolarHBondContact O-N 3.32Å
35G97.2Very high97.4Very high76 Ų76102.9 Ų102.978%0.78460%0.603SS**THydrogen-bonded Turntrans862.3-175.400000114.6L33L33-G35 PolarHBondContact O-N 3.13Å
36K98.4Very high97Very high147 Ų147112.4 Ų112.464%0.63964%0.64SS**SBendtrans-104.7146.9168.4-56.7-63.3-179.3-179.70110.7L33 L38L33-K36 WeakPolarHBondContact O-CB 3.47Å; L33-K36 PolarHBondContact O-N 2.94Å; K36-L38 HydrophobicContact CB-CD2 4.09Å
37V97.9Very high96.9Very high151 Ų151110.2 Ų110.292%0.91564%0.636SS**  trans-82.9131.2165.3179.80000107.5
38L97.7Very high96.9Very high66 Ų66113.3 Ų113.335%0.34665%0.652SS.*  trans-118.5133.5-175.3-55.8-179.1000110.6L33 K36L33-L38 HydrophobicContact CB-CD1 4.1Å; L33-L38 HydrophobicContact CB-CD2 4.12Å; L33-L38 HydrophobicContact CD1-CD1 3.96Å; L33-L38 HydrophobicContact CD1-CD2 3.83Å; K36-L38 HydrophobicContact CB-CD2 4.09Å
39L98.2Very high96.8Very high145 Ų145115.5 Ų115.576%0.75966%0.663SS**  trans-106.1128163.2-178.762.6000107.6E41L39-E41 HydrophobicContact CD2-CG 4.5Å; L39-E41 VanDerWaalsContact CD2-OE1 3.32Å; L39-E41 WeakPolarHBondContact CD2-OE1 3.41Å; L39-E41 HydrophobicContact CG-CG 4.17Å
40I97.4Very high96.8Very high122 Ų122119 Ų11963%0.62668%0.679SS**  trans-118.9121.2-178.2-61.4171.6000107.8V14V14-I40 HydrophobicContact CG1-CD1 4.49Å
41E97.9Very high96.8Very high138 Ų138123.8 Ų123.865%0.64571%0.707SS**  trans-124.1140.5-177-62.9-175.7176.200110.9L39L39-E41 HydrophobicContact CD2-CG 4.5Å; L39-E41 VanDerWaalsContact CD2-OE1 3.32Å; L39-E41 WeakPolarHBondContact CD2-OE1 3.41Å; L39-E41 HydrophobicContact CG-CG 4.17Å
42N97Very high96.7Very high163 Ų163130.1 Ų130.187%0.87274%0.735SS**  trans-85126165.568.5-76000109
43V97Very high96.6Very high128 Ų128133.3 Ų133.378%0.77675%0.745SS**  trans-112.9155.3-178.9-62.30000111.4
44A97.1Very high96.5Very high99 Ų99138.4 Ų138.482%0.81878%0.775SS**  trans-146145.1170.500000109.3
45S95.6Very high96.5Very high125 Ų125134.3 Ų134.387%0.87478%0.781SS**  trans-89150.3172-56.70000110.5
46L86.5Confident96.4Very high251 Ų251139.5 Ų139.5100%1.31478%0.78SS**  trans-86.20172.8-73.2164.6000111.7

Retrieved 46 of 46 residues in 16.9 ms (Link to these results)