X5DRH4_HUMAN Loading...

Oxytocin receptor isoform A

AlphaFold DB , UniProt , Accession X5DRH4, Species HUMAN (Homo sapiens, Human), Gene OXTR, Length 53 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M51.5Low62.1Low248 Ų248144.5 Ų144.5100%1.22284%0.84SS**  092.80-80.1172.2176.600107.5
2E53.2Low62.8Low192 Ų192152.8 Ų152.890%0.89785%0.847SS**  trans-87.1108.8175.3-81.1177.597.200109.1R4E2-R4 PolarHBondContact O-N 3.01Å
3A58.3Low64.2Low94 Ų94154.8 Ų154.878%0.77785%0.846SS**  trans-7293.3171.300000108.5S5A3-S5 PolarHBondContact O-N 3.01Å
4R56.1Low65.1Low230 Ų230151.7 Ų151.787%0.86884%0.837SS**  trans-56.1106.8168.7-86.1175.3157.8-172.3-5.9109.2E2 Q6E2-R4 PolarHBondContact O-N 3.01Å; R4-Q6 PolarHBondContact O-N 3.01Å
5S68.1Low66.2Low121 Ų121150.5 Ų150.585%0.84684%0.836SS**  trans-64.9100.9169.6-51.10000108.8A3A3-S5 PolarHBondContact O-N 3.01Å
6Q66.9Low67.1Low173 Ų173148.4 Ų148.481%0.80883%0.831SS**  trans-69130.9168.9-76.5177.366.300108.6R4 T8R4-Q6 PolarHBondContact O-N 3.01Å; Q6-T8 PolarHBondContact O-N 2.99Å
7P62.8Low67.9Low126 Ų126144.8 Ų144.882%0.81883%0.825SS**  trans-68.210416527.6-29.2000106.7G9P7-G9 PolarHBondContact O-N 2.73Å
8T65.9Low68.6Low131 Ų131143.7 Ų143.780%0.80482%0.824SS**  trans-57110.7171.9-45.90000107.1Q6 A10Q6-T8 PolarHBondContact O-N 2.99Å; T8-A10 PolarHBondContact O-N 2.96Å
9G63Low69.1Low77 Ų77149 Ų14979%0.79483%0.829SS**  trans-69.256.2178.700000111.7P7P7-G9 PolarHBondContact O-N 2.73Å
10A68.8Low69.4Low70 Ų70153.8 Ų153.858%0.57983%0.834SS**  trans-62.5128173.100000107.9T8 R12T8-A10 PolarHBondContact O-N 2.96Å; A10-R12 PolarHBondContact O-N 3.06Å
11P68.6Low69.7Low128 Ų128158.1 Ų158.183%0.83184%0.838SS**  trans-58.7115.4175.522.4-30.2000108Q13P11-Q13 PolarHBondContact O-N 3Å
12R70.7Confident71.1Confident243 Ų243149 Ų14992%0.91781%0.808SS**  trans-66.5109.6175.3-78.9-177.1169.5-161.2-3107.5A10A10-R12 PolarHBondContact O-N 3.06Å
13Q80.1Confident72.2Confident179 Ų179146.2 Ų146.284%0.83681%0.807SS**PPolyproline II helixtrans-56.3128.8173.1-166.5174.62.900108.7P11 T15P11-Q13 PolarHBondContact O-N 3Å; Q13-T15 PolarHBondContact O-N 3.43Å
14P77.6Confident72.7Confident112 Ų112153 Ų15373%0.72781%0.812SS**PPolyproline II helixtrans-65.5133.6178.123.9-30.8000109.7
15T82Confident73.3Confident134 Ų134146.4 Ų146.482%0.82281%0.807SS**PPolyproline II helixtrans-59127.4178.1-490000109.7Q13 A17Q13-T15 PolarHBondContact O-N 3.43Å; T15-A17 PolarHBondContact O-N 3.45Å
16P80Confident73.2Confident116 Ų116147.3 Ų147.375%0.75381%0.807SS**PPolyproline II helixtrans-61.8136.617922.2-30.7000110.9
17A81.6Confident73.5Confident88 Ų88142.8 Ų142.873%0.72780%0.8SS**PPolyproline II helixtrans-64.5141.5-177.400000111.5T15 R19T15-A17 PolarHBondContact O-N 3.45Å; A17-R19 PolarHBondContact O-N 3.25Å
18P79.9Confident73.8Confident125 Ų125142.2 Ų142.281%0.81280%0.796SS**PPolyproline II helixtrans-64.9126.2179.824.8-32.2000110.8R20P18-R20 PolarHBondContact O-N 3.14Å
19R78.6Confident73.9Confident244 Ų244141.8 Ų141.892%0.92180%0.796SS**PPolyproline II helixtrans-63.9119.6172.3-85.7-174.5166.3-145.3-1.8109.5A17 R21A17-R19 PolarHBondContact O-N 3.25Å; R19-R21 PolarHBondContact O-N 3.31Å
20R75.4Confident74.4Confident244 Ų244142.9 Ų142.992%0.92178%0.783SS**PPolyproline II helixtrans-61.7121172-77.9-173.9164.2-168.9-4109.2P18 G22P18-R20 PolarHBondContact O-N 3.14Å; R20-G22 PolarHBondContact O-N 3.26Å
21R75.4Confident74.2Confident246 Ų246144.3 Ų144.393%0.92879%0.786SS**PPolyproline II helixtrans-67.3118.1167.9-61.7-177.4-159-159.24.7106.4R19R19-R21 PolarHBondContact O-N 3.31Å
22G80.1Confident73.9Confident56 Ų56147.8 Ų147.858%0.57778%0.783SS**PPolyproline II helixtrans-57.8167.7176.900000111.8R20 R24R20-G22 PolarHBondContact O-N 3.26Å; G22-R24 PolarHBondContact O-N 3.24Å; G22-R24 VanDerWaalsContact O-N 3.14Å
23P75.6Confident73.3Confident134 Ų134138.7 Ų138.787%0.8777%0.765SS**PPolyproline II helixtrans-54.3124.9177.122.9-31.6000109.1A25P23-A25 PolarHBondContact O-N 2.99Å; P23-A25 VanDerWaalsContact O-N 3.08Å
24R69.2Low72.3Confident235 Ų235133.8 Ų133.889%0.88776%0.755SS**  trans-61.5115.5175.2-172.7175.5-167.9-176.21.3106.7G22 T26G22-R24 PolarHBondContact O-N 3.24Å; G22-R24 VanDerWaalsContact O-N 3.14Å; R24-T26 PolarHBondContact O-N 3.08Å
25A68.5Low71.4Confident93 Ų93133.5 Ų133.577%0.76975%0.751SS**  trans-58.3111.7174.300000108.3P23 A27P23-A25 PolarHBondContact O-N 2.99Å; P23-A25 VanDerWaalsContact O-N 3.08Å; A25-A27 PolarHBondContact O-N 3.01Å; A25-A27 VanDerWaalsContact O-N 3.17Å
26T67.3Low70.2Confident139 Ų139135.8 Ų135.885%0.85375%0.745SS**  trans-68.8109.5168.9-45.50000105.9R24R24-T26 PolarHBondContact O-N 3.08Å
27A71.8Confident69.2Low79 Ų79133.6 Ų133.665%0.65373%0.731SS**PPolyproline II helixtrans-55.6139.7176.300000109.3A25A25-A27 PolarHBondContact O-N 3.01Å; A25-A27 VanDerWaalsContact O-N 3.17Å
28P69.6Low68.1Low114 Ų114140 Ų14074%0.7474%0.736SS**PPolyproline II helixtrans-56.3143.3175.122.2-31.2000109.7D30P28-D30 PolarHBondContact O-N 2.85Å
29P67.6Low67Low122 Ų122142.8 Ų142.879%0.79273%0.731SS**PPolyproline II helixtrans-58.4138-177.924-32.8000110.4
30D74.2Confident66.1Low99 Ų99133.9 Ų133.953%0.52971%0.709SS.*PPolyproline II helixtrans-58.3128.1-178.8-176.7-84.5000110.8P28 R32 G33P28-D30 PolarHBondContact O-N 2.85Å; D30-R32 PolarHBondContact O-N 3.1Å; D30-R32 PolarHBondContact OD1-N 3.43Å; D30-R32 WeakPolarHBondContact OD1-CG 3.49Å; D30-R32 WeakPolarHBondContact OD1-CA 3.32Å; D30-R32 VanDerWaalsContact O-N 3.13Å; D30-R32 WeakPolarHBondContact OD1-CB 3.31Å; D30-G33 PolarHBondContact O-N 3Å
31P63.6Low65.5Low100 Ų100131 Ų13165%0.64970%0.698SS**Hα-helixtrans-65.7-16-175.625-33.4000113.5G33 A34 T35P31-G33 PolarHBondContact O-N 3.22Å; P31-A34 WeakPolarHBondContact O-CB 3.4Å; P31-A34 PolarHBondContact O-N 2.94Å; P31-A34 VanDerWaalsContact O-N 3.15Å; P31-T35 PolarHBondContact O-OG1 3.17Å
32R62.3Low64.9Low202 Ų202128.5 Ų128.576%0.76269%0.689SS**Hα-helixtrans-71.3-18.6173.9-53.4173.8176.3-174.1-0.5112.2D30D30-R32 PolarHBondContact O-N 3.1Å; D30-R32 PolarHBondContact OD1-N 3.43Å; D30-R32 WeakPolarHBondContact OD1-CG 3.49Å; D30-R32 WeakPolarHBondContact OD1-CA 3.32Å; D30-R32 VanDerWaalsContact O-N 3.13Å; D30-R32 WeakPolarHBondContact OD1-CB 3.31Å
33G59.3Low64Low52 Ų52134.5 Ų134.554%0.53669%0.694SS.*Hα-helixtrans-70.2-31.4169.400000112.9D30 P31D30-G33 PolarHBondContact O-N 3Å; P31-G33 PolarHBondContact O-N 3.22Å
34A59Low63.3Low76 Ų76137 Ų13763%0.62869%0.686SS**Hα-helixtrans-79-19.7-176.500000113.8P31 R36 P37P31-A34 WeakPolarHBondContact O-CB 3.4Å; P31-A34 PolarHBondContact O-N 2.94Å; P31-A34 VanDerWaalsContact O-N 3.15Å; A34-R36 VanDerWaalsContact C-N 3.29Å; A34-R36 PolarHBondContact O-N 3.41Å; A34-P37 WeakPolarHBondContact O-CD 3.03Å
35T58.7Low63.1Low106 Ų106129.3 Ų129.365%0.6567%0.668SS**THydrogen-bonded Turntrans-82.6-1.1178.6-26.60000113.5P31P31-T35 PolarHBondContact O-OG1 3.17Å
36R56Low62.8Low181 Ų181128 Ų12868%0.68365%0.653SS**Hα-helixtrans-88.4-8.4-176.6-63.8179.395168.45.5118A34 W38 R39 A40A34-R36 VanDerWaalsContact C-N 3.29Å; A34-R36 PolarHBondContact O-N 3.41Å; R36-W38 VanDerWaalsContact C-N 3.35Å; R36-W38 PolarHBondContact O-N 2.89Å; R36-R39 PolarHBondContact O-N 3.5Å; R36-A40 PolarHBondContact O-N 3.49Å; R36-A40 VanDerWaalsContact O-N 3.1Å
37P59.5Low62.4Low71 Ų71125.4 Ų125.446%0.46164%0.636SS.*Hα-helixtrans-66.4-39.4-177.924.6-29.3000111.3A34 A40 W41A34-P37 WeakPolarHBondContact O-CD 3.03Å; P37-A40 PolarHBondContact O-N 3.4Å; P37-W41 PolarHBondContact O-N 3.02Å; P37-W41 VanDerWaalsContact O-CD1 3.22Å
38W58.4Low61.7Low222 Ų222125.3 Ų125.384%0.84163%0.631SS**Hα-helixtrans-70.3-36.5179.1-75.189.9000113.7R36 R42R36-W38 VanDerWaalsContact C-N 3.35Å; R36-W38 PolarHBondContact O-N 2.89Å; W38-R42 PolarHBondContact O-N 3.43Å; W38-R42 VanDerWaalsContact O-N 3.1Å; W38-R42 WeakPolarHBondContact O-CB 3.21Å
39R57Low61.2Low183 Ų183124 Ų12469%0.69162%0.624SS**Hα-helixtrans-67.5-41.3175.3-84.9-175.2174.3-99.62.4111.4R36 W41 R42 W43R36-R39 PolarHBondContact O-N 3.5Å; R39-W41 VanDerWaalsContact C-N 3.34Å; R39-W41 PolarHBondContact O-N 3.49Å; R39-R42 PolarHBondContact O-N 2.95Å; R39-W43 VanDerWaalsContact O-CD1 3.23Å; R39-W43 PolarHBondContact O-N 3.48Å
40A60.6Low60.8Low57 Ų57122.8 Ų122.847%0.47162%0.617SS.*Hα-helixtrans-62.9-39.4178.700000112.6R36 P37 R44R36-A40 PolarHBondContact O-N 3.49Å; R36-A40 VanDerWaalsContact O-N 3.1Å; P37-A40 PolarHBondContact O-N 3.4Å; A40-R44 PolarHBondContact O-N 3.05Å
41W60.9Low60Low184 Ų184122.5 Ų122.570%0.69762%0.623SS**Hα-helixtrans-68.3-40.3175.5-8465.4000112.8P37 R39 W43 R44 C45P37-W41 PolarHBondContact O-N 3.02Å; P37-W41 VanDerWaalsContact O-CD1 3.22Å; R39-W41 VanDerWaalsContact C-N 3.34Å; R39-W41 PolarHBondContact O-N 3.49Å; W41-W43 PolarHBondContact O-N 3.07Å; W41-R44 PolarHBondContact O-N 3.32Å; W41-C45 PolarHBondContact O-N 3.22Å
42R64.2Low59.6Low193 Ų193129.3 Ų129.373%0.72864%0.636SS**Hα-helixtrans-61.9-40.7178.5-168.7173.7173.6-178.1-2.3112.5W38 R39 C45 C46W38-R42 PolarHBondContact O-N 3.43Å; W38-R42 VanDerWaalsContact O-N 3.1Å; W38-R42 WeakPolarHBondContact O-CB 3.21Å; R39-R42 PolarHBondContact O-N 2.95Å; R42-C45 PolarHBondContact O-N 3.2Å; R42-C46 WeakPolarHBondContact O-CB 3.37Å; R42-C46 PolarHBondContact O-N 3.23Å; R42-C46 PolarHBondContact O-SG 3.28Å
43W60.8Low59Low182 Ų182133.3 Ų133.369%0.68965%0.651SS**Hα-helixtrans-65.1-41.1174.9-80.598.8000112.4R39 W41 C45 C46 V47R39-W43 VanDerWaalsContact O-CD1 3.23Å; R39-W43 PolarHBondContact O-N 3.48Å; W41-W43 PolarHBondContact O-N 3.07Å; W43-C45 PolarHBondContact O-N 2.96Å; W43-C46 PolarHBondContact O-N 3.1Å; W43-V47 WeakPolarHBondContact O-CG2 3.5Å; W43-V47 PolarHBondContact O-N 3.47Å
44R61.6Low59Low187 Ų187137.4 Ų137.471%0.70666%0.657SS**Hα-helixtrans-60.4-45176.1-98.1176.7125.3-115.80.9112.2A40 W41 S48A40-R44 PolarHBondContact O-N 3.05Å; W41-R44 PolarHBondContact O-N 3.32Å; R44-S48 WeakPolarHBondContact O-CB 3.37Å; R44-S48 PolarHBondContact O-N 3.43Å; R44-S48 PolarHBondContact O-OG 3.41Å; R44-S48 VanDerWaalsContact O-OG 3.07Å
45C63.3Low59Low74 Ų74140.6 Ų140.650%0.566%0.658SS.*Hα-helixtrans-67.8-41.9178-63.30000112.3W41 R42 W43 V47 S48 S49W41-C45 PolarHBondContact O-N 3.22Å; R42-C45 PolarHBondContact O-N 3.2Å; W43-C45 PolarHBondContact O-N 2.96Å; C45-V47 PolarHBondContact O-N 3.32Å; C45-S48 PolarHBondContact O-N 3.45Å; C45-S49 WeakPolarHBondContact O-CB 3.48Å; C45-S49 PolarHBondContact O-N 3.44Å; C45-S49 PolarHBondContact O-OG 3.02Å
46C62.1Low59Low66 Ų66142.5 Ų142.545%0.44666%0.659SS.*Hα-helixtrans-62.2-43.7177.3-69.90000111.8R42 W43 S49 C50R42-C46 WeakPolarHBondContact O-CB 3.37Å; R42-C46 PolarHBondContact O-N 3.23Å; R42-C46 PolarHBondContact O-SG 3.28Å; W43-C46 PolarHBondContact O-N 3.1Å; C46-S49 PolarHBondContact O-N 3.15Å; C46-C50 VanDerWaalsContact O-CB 3.31Å; C46-C50 WeakPolarHBondContact O-CB 2.97Å; C46-C50 PolarHBondContact O-N 3.36Å; C46-C50 PolarHBondContact O-SG 3.15Å
47V59.9Low59.2Low84 Ų84140.2 Ų140.251%0.50966%0.657SS.*Hα-helixtrans-66.3-45177174.10000111.1W43 C45 S49 C50 S51W43-V47 WeakPolarHBondContact O-CG2 3.5Å; W43-V47 PolarHBondContact O-N 3.47Å; C45-V47 PolarHBondContact O-N 3.32Å; V47-S49 VanDerWaalsContact C-N 3.34Å; V47-S49 PolarHBondContact O-N 3.38Å; V47-C50 PolarHBondContact O-N 3.13Å; V47-S51 PolarHBondContact O-N 3.4Å; V47-S51 PolarHBondContact O-OG 3.1Å
48S58Low59.2Low77 Ų77144.6 Ų144.654%0.53867%0.67SS.*Hα-helixtrans-62.1-39.1177.7-670000113R44 C45R44-S48 WeakPolarHBondContact O-CB 3.37Å; R44-S48 PolarHBondContact O-N 3.43Å; R44-S48 PolarHBondContact O-OG 3.41Å; R44-S48 VanDerWaalsContact O-OG 3.07Å; C45-S48 PolarHBondContact O-N 3.45Å
49S58Low59.2Low85 Ų85139.4 Ų139.459%0.59466%0.658SS**Hα-helixtrans-74.1-29175.9-640000113.2C45 C46 V47C45-S49 WeakPolarHBondContact O-CB 3.48Å; C45-S49 PolarHBondContact O-N 3.44Å; C45-S49 PolarHBondContact O-OG 3.02Å; C46-S49 PolarHBondContact O-N 3.15Å; V47-S49 VanDerWaalsContact C-N 3.34Å; V47-S49 PolarHBondContact O-N 3.38Å
50C59Low59.4Low97 Ų97136.3 Ų136.366%0.65566%0.656SS**Hα-helixtrans-74.2-27.9174.2-72.30000113.1C46 V47C46-C50 VanDerWaalsContact O-CB 3.31Å; C46-C50 WeakPolarHBondContact O-CB 2.97Å; C46-C50 PolarHBondContact O-N 3.36Å; C46-C50 PolarHBondContact O-SG 3.15Å; V47-C50 PolarHBondContact O-N 3.13Å
51S57.2Low59.3Low93 Ų93142.4 Ų142.465%0.6567%0.67SS**THydrogen-bonded Turntrans-82.8-10.4179.3-58.60000114.4V47V47-S51 PolarHBondContact O-N 3.4Å; V47-S51 PolarHBondContact O-OG 3.1Å
52W56.1Low59.1Low244 Ų244138.9 Ų138.992%0.92467%0.668SS**THydrogen-bonded Turntrans-94.84.3178.2-105.60.8000113.8
53R49.4Very low58.7Low285 Ų285134 Ų134100%1.07566%0.663SS**  trans-111.40-177-159.3171.9175.4-83-0.2111.9

Retrieved 53 of 53 residues in 10.7 ms (Link to these results)