X6RKQ2_HUMAN Loading...

Nucleoporin 50

AlphaFold DB , UniProt , Accession X6RKQ2, Species HUMAN (Homo sapiens, Human), Gene NUP50, Length 45 aa.

						>X6RKQ2_HUMAN|X6RKQ2|NUP50
MAKRNAEKELTDRNWDQEDEAEEVGTFSMASEEVLKNRAIKKAKR
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	73.4	Confident	93	Very high	210 Å²	210	148.5 Å²	148.5	100%	1.034	76%	0.758	S	S	*	*				0	131.4	0	-73.9	-65.1	-88.5	0	0	108.2	K3	M1-K3 HydrophobicContact CE-CD 4.37Å; M1-K3 VanDerWaalsContact C-N 3.33Å
2	A	94.8	Very high	93.3	Very high	103 Å²	103	146.9 Å²	146.9	85%	0.851	75%	0.752	S	S	*	*			trans	-88.1	1.4	-177.9	0	0	0	0	0	113.9	R4	A2-R4 PolarHBondContact O-N 3.46Å
3	K	95.6	Very high	93.5	Very high	184 Å²	184	150.9 Å²	150.9	80%	0.8	75%	0.752	S	S	*	*			trans	-67.4	129.4	175.1	-67.7	179.8	179.7	-80.7	0	108.9	M1	M1-K3 HydrophobicContact CE-CD 4.37Å; M1-K3 VanDerWaalsContact C-N 3.33Å
4	R	95.4	Very high	93.6	Very high	226 Å²	226	143.2 Å²	143.2	85%	0.853	72%	0.715	S	S	*	*			trans	-112	150.8	175.5	-61.3	-168.8	-67.4	133.4	-3.1	109.8	A2	A2-R4 PolarHBondContact O-N 3.46Å
5	N	96	Very high	93.7	Very high	160 Å²	160	145.7 Å²	145.7	86%	0.856	71%	0.712	S	S	*	*			trans	-79.6	174.2	167.8	-64.8	-21.5	0	0	0	110
6	A	95	Very high	93.8	Very high	90 Å²	90	143.6 Å²	143.6	74%	0.744	71%	0.705	S	S	*	*			trans	-61.1	154.6	173.7	0	0	0	0	0	111.7
7	E	92.9	Very high	93.8	Very high	170 Å²	170	142.9 Å²	142.9	79%	0.794	70%	0.7	S	S	*	*	S	Bend	trans	-76.3	-40	-179.3	-177	173.9	168.8	0	0	113
8	K	92.9	Very high	93.5	Very high	132 Å²	132	145.9 Å²	145.9	57%	0.574	71%	0.712	S	S	*	*	S	Bend	trans	-122.5	148.2	175.9	-60.8	176.7	-172.1	171.7	0	109.4	L10 D19	K8-L10 PolarHBondContact O-N 3.14Å; K8-D19 IonicContact NZ-OD1 2.7Å; K8-D19 PolarHBondContact NZ-OD1 2.76Å
9	E	94.9	Very high	93.3	Very high	170 Å²	170	144.5 Å²	144.5	79%	0.794	71%	0.709	S	S	*	*			trans	-76.4	113.4	171.8	-67.7	-173.1	168.1	0	0	109.9	N14	E9-N14 PolarHBondContact O-ND2 3.5Å
10	L	95.6	Very high	93	Very high	141 Å²	141	146.6 Å²	146.6	74%	0.738	72%	0.716	S	S	*	*			trans	-85	131.8	176.5	-162.4	69.9	0	0	0	110	K8 W15	K8-L10 PolarHBondContact O-N 3.14Å; L10-W15 HydrophobicContact CD1-CB 4.05Å; L10-W15 HydrophobicContact CG-CB 4.26Å
11	T	96.3	Very high	92.7	Very high	48 Å²	48	144 Å²	144	29%	0.294	72%	0.719	S	S	.	*			trans	-135.3	167.5	-173.6	71.2	0	0	0	0	110.5	R13 N14 W15	T11-R13 PolarHBondContact O-N 3.17Å; T11-R13 VanDerWaalsContact O-N 3.09Å; T11-R13 PolarHBondContact OG1-N 3.2Å; T11-N14 PolarHBondContact OG1-N 2.93Å; T11-N14 PolarHBondContact OG1-OD1 3.21Å; T11-N14 PolarHBondContact O-OD1 3.31Å; T11-N14 PolarHBondContact N-OD1 3.42Å; T11-N14 WeakPolarHBondContact CB-OD1 3.33Å; T11-N14 WeakPolarHBondContact CA-OD1 3.44Å; T11-N14 PolarHBondContact O-N 3.32Å; T11-W15 WeakPolarHBondContact O-CB 3.44Å; T11-W15 PolarHBondContact O-N 2.99Å
12	D	96.8	Very high	93.4	Very high	129 Å²	129	142.4 Å²	142.4	69%	0.69	71%	0.709	S	S	*	*	T	Hydrogen-bonded Turn	trans	-59.9	-14.1	172	59.1	-4.3	0	0	0	114.6
13	R	96.6	Very high	93.3	Very high	199 Å²	199	146.3 Å²	146.3	75%	0.751	71%	0.709	S	S	*	*	T	Hydrogen-bonded Turn	trans	-109.7	-6.1	-174.8	-71.5	172.2	-69	163.6	3.3	114.7	T11	T11-R13 PolarHBondContact O-N 3.17Å; T11-R13 VanDerWaalsContact O-N 3.09Å; T11-R13 PolarHBondContact OG1-N 3.2Å
14	N	94.5	Very high	93.1	Very high	43 Å²	43	144.9 Å²	144.9	23%	0.23	72%	0.716	C	S	.	*	T	Hydrogen-bonded Turn	trans	-135.7	6.7	-177.4	71	-10.5	0	0	0	114.3	E9 T11 D16 Q17	E9-N14 PolarHBondContact O-ND2 3.5Å; T11-N14 PolarHBondContact OG1-N 2.93Å; T11-N14 PolarHBondContact OG1-OD1 3.21Å; T11-N14 PolarHBondContact O-OD1 3.31Å; T11-N14 PolarHBondContact N-OD1 3.42Å; T11-N14 WeakPolarHBondContact CB-OD1 3.33Å; T11-N14 WeakPolarHBondContact CA-OD1 3.44Å; T11-N14 PolarHBondContact O-N 3.32Å; N14-D16 VanDerWaalsContact C-N 3.26Å; N14-D16 PolarHBondContact O-N 3.14Å; N14-Q17 PolarHBondContact O-N 3.3Å; N14-Q17 HydrophobicContact CB-CG 4.36Å
15	W	94.8	Very high	93	Very high	180 Å²	180	137.2 Å²	137.2	68%	0.682	71%	0.707	S	S	*	*	T	Hydrogen-bonded Turn	trans	-72	-19.4	-176.3	74.6	-80.2	0	0	0	114.2	L10 T11	L10-W15 HydrophobicContact CD1-CB 4.05Å; L10-W15 HydrophobicContact CG-CB 4.26Å; T11-W15 WeakPolarHBondContact O-CB 3.44Å; T11-W15 PolarHBondContact O-N 2.99Å
16	D	94.8	Very high	93	Very high	112 Å²	112	135.9 Å²	135.9	60%	0.599	71%	0.705	S	S	*	*	T	Hydrogen-bonded Turn	trans	-98.8	8.2	-178.1	63	-25	0	0	0	112.9	N14	N14-D16 VanDerWaalsContact C-N 3.26Å; N14-D16 PolarHBondContact O-N 3.14Å
17	Q	93.8	Very high	92.9	Very high	133 Å²	133	139.5 Å²	139.5	62%	0.621	70%	0.704	S	S	*	*	P	Polyproline II helix	trans	-79	133.4	176.3	-63.8	179.3	8.6	0	0	110.3	N14	N14-Q17 PolarHBondContact O-N 3.3Å; N14-Q17 HydrophobicContact CB-CG 4.36Å
18	E	89.3	Confident	93.1	Very high	196 Å²	196	137 Å²	137	92%	0.916	71%	0.706	S	S	*	*	P	Polyproline II helix	trans	-76.4	126	172.4	-65.7	-179.1	179.2	0	0	109.6
19	D	88.8	Confident	93.2	Very high	120 Å²	120	138 Å²	138	64%	0.642	71%	0.714	S	S	*	*	P	Polyproline II helix	trans	-74.7	135.3	166.8	-76.7	-50.1	0	0	0	109.2	K8 A21	K8-D19 IonicContact NZ-OD1 2.7Å; K8-D19 PolarHBondContact NZ-OD1 2.76Å; D19-A21 PolarHBondContact O-N 2.93Å
20	E	88.3	Confident	93.3	Very high	185 Å²	185	131.6 Å²	131.6	86%	0.864	69%	0.69	S	S	*	*	P	Polyproline II helix	trans	-62.4	128.1	171.2	-172.2	171.6	-164.5	0	0	109.1	E22	E20-E22 PolarHBondContact O-N 3.43Å; E20-E22 VanDerWaalsContact O-N 3.08Å
21	A	87.2	Confident	93.4	Very high	93 Å²	93	128.1 Å²	128.1	77%	0.769	68%	0.678	S	S	*	*			trans	-65.1	113.1	178.8	0	0	0	0	0	109.6	D19 E23	D19-A21 PolarHBondContact O-N 2.93Å; A21-E23 PolarHBondContact O-N 3.35Å
22	E	88.3	Confident	93.4	Very high	176 Å²	176	132.2 Å²	132.2	82%	0.822	69%	0.693	S	S	*	*			trans	-68.5	132.8	178.5	-66.1	-173.4	178	0	0	111.5	E20	E20-E22 PolarHBondContact O-N 3.43Å; E20-E22 VanDerWaalsContact O-N 3.08Å
23	E	91.4	Very high	93.4	Very high	185 Å²	185	133 Å²	133	86%	0.864	69%	0.693	S	S	*	*			trans	-79.3	142.9	170.9	-64.2	-173	175.1	0	0	111.1	A21 G25	A21-E23 PolarHBondContact O-N 3.35Å; E23-G25 PolarHBondContact O-N 3.35Å
24	V	92.4	Very high	93.4	Very high	154 Å²	154	127 Å²	127	93%	0.933	68%	0.678	S	S	*	*			trans	-68.3	101.8	171.1	-178.4	0	0	0	0	108.9
25	G	91.9	Very high	93.5	Very high	65 Å²	65	127.9 Å²	127.9	67%	0.67	68%	0.683	S	S	*	*			trans	-79.6	178.6	178.7	0	0	0	0	0	114.3	E23	E23-G25 PolarHBondContact O-N 3.35Å
26	T	95.7	Very high	93.6	Very high	133 Å²	133	126.3 Å²	126.3	82%	0.816	68%	0.681	S	S	*	*			trans	-104.5	140.7	169.2	-58.6	0	0	0	0	109.5
27	F	94.3	Very high	93.7	Very high	166 Å²	166	127.7 Å²	127.7	73%	0.728	69%	0.688	S	S	*	*	P	Polyproline II helix	trans	-66.1	145.4	176.3	69.1	-89.2	0	0	0	111.1	M29	F27-M29 HydrophobicContact CE2-CG 4.15Å; F27-M29 PolarHBondContact O-N 3.5Å
28	S	95.8	Very high	93.9	Very high	118 Å²	118	128.5 Å²	128.5	83%	0.825	69%	0.686	S	S	*	*	P	Polyproline II helix	trans	-68	125.7	175.1	-50	0	0	0	0	110.7
29	M	96.5	Very high	94.2	Very high	152 Å²	152	123.7 Å²	123.7	75%	0.749	68%	0.679	S	S	*	*	P	Polyproline II helix	trans	-73.6	142.2	172	-66.3	-174.3	67.6	0	0	110.3	F27	F27-M29 HydrophobicContact CE2-CG 4.15Å; F27-M29 PolarHBondContact O-N 3.5Å
30	A	96.4	Very high	94.6	Very high	35 Å²	35	124.1 Å²	124.1	29%	0.289	68%	0.68	S	S	.	*	P	Polyproline II helix	trans	-64	149.7	170.6	0	0	0	0	0	110.4	V34 L35	A30-V34 HydrophobicContact CB-CG1 4.01Å; A30-V34 HydrophobicContact CB-CB 4.23Å; A30-L35 HydrophobicContact CB-CD2 4.1Å; A30-L35 WeakPolarHBondContact O-CD1 3.46Å; A30-L35 HydrophobicContact CB-CG 4.19Å
31	S	97.6	Very high	95	Very high	68 Å²	68	124.6 Å²	124.6	48%	0.476	68%	0.68	S	S	.	*	P	Polyproline II helix	trans	-64	160.4	177	66.6	0	0	0	0	112	E33 V34 L35	S31-E33 VanDerWaalsContact C-N 3.28Å; S31-E33 PolarHBondContact O-N 3.08Å; S31-V34 PolarHBondContact O-N 3.09Å; S31-V34 VanDerWaalsContact O-N 3.14Å; S31-V34 WeakPolarHBondContact OG-CG2 3.41Å; S31-L35 WeakPolarHBondContact O-CG 2.85Å; S31-L35 PolarHBondContact O-N 3.18Å
32	E	96.4	Very high	95.4	Very high	134 Å²	134	128.8 Å²	128.8	63%	0.626	68%	0.68	S	S	*	*	H	α-helix	trans	-59.3	-39.1	-177.9	-157.2	-164.3	140.6	0	0	112.6	V34 L35 K36	E32-V34 VanDerWaalsContact C-N 3.33Å; E32-V34 PolarHBondContact O-N 3.33Å; E32-L35 PolarHBondContact O-N 2.7Å; E32-K36 PolarHBondContact OE1-NZ 3.39Å; E32-K36 IonicContact OE1-NZ 2.76Å; E32-K36 WeakPolarHBondContact OE1-CE 3.38Å; E32-K36 PolarHBondContact O-N 2.69Å; E32-K36 WeakPolarHBondContact O-CG 3.49Å
33	E	96.4	Very high	95.8	Very high	146 Å²	146	123.7 Å²	123.7	68%	0.682	67%	0.668	S	S	*	*	H	α-helix	trans	-60.2	-42	177.2	-175.6	-179.4	-178.7	0	0	112.2	S31 N37	S31-E33 VanDerWaalsContact C-N 3.28Å; S31-E33 PolarHBondContact O-N 3.08Å; E33-N37 PolarHBondContact O-ND2 3.27Å
34	V	97.5	Very high	96	Very high	73 Å²	73	124.7 Å²	124.7	44%	0.442	67%	0.67	S	S	.	*	H	α-helix	trans	-68.7	-41.2	176.4	174.9	0	0	0	0	110.3	A30 S31 E32 K36 N37 R38	A30-V34 HydrophobicContact CB-CG1 4.01Å; A30-V34 HydrophobicContact CB-CB 4.23Å; S31-V34 PolarHBondContact O-N 3.09Å; S31-V34 VanDerWaalsContact O-N 3.14Å; S31-V34 WeakPolarHBondContact OG-CG2 3.41Å; E32-V34 VanDerWaalsContact C-N 3.33Å; E32-V34 PolarHBondContact O-N 3.33Å; V34-K36 PolarHBondContact O-N 2.95Å; V34-N37 PolarHBondContact O-N 3.4Å; V34-R38 WeakPolarHBondContact O-CB 3.49Å; V34-R38 PolarHBondContact O-N 3.34Å
35	L	96.9	Very high	96	Very high	62 Å²	62	130.2 Å²	130.2	33%	0.325	67%	0.674	S	S	.	*	H	α-helix	trans	-66.3	-36.1	-179	-69.8	175.5	0	0	0	112.8	A30 S31 E32 N37 R38 I40	A30-L35 HydrophobicContact CB-CD2 4.1Å; A30-L35 WeakPolarHBondContact O-CD1 3.46Å; A30-L35 HydrophobicContact CB-CG 4.19Å; S31-L35 WeakPolarHBondContact O-CG 2.85Å; S31-L35 PolarHBondContact O-N 3.18Å; E32-L35 PolarHBondContact O-N 2.7Å; L35-N37 VanDerWaalsContact C-N 3.26Å; L35-N37 PolarHBondContact O-N 2.78Å; L35-R38 PolarHBondContact O-N 3.45Å; L35-R38 VanDerWaalsContact O-N 3.17Å; L35-I40 HydrophobicContact CD2-CD1 4.15Å
36	K	96.4	Very high	96.2	Very high	146 Å²	146	133.5 Å²	133.5	64%	0.635	67%	0.674	S	S	*	*	H	α-helix	trans	-57.6	-38.2	177.7	-76.3	172.7	-168.2	178.4	0	113	E32 V34	E32-K36 PolarHBondContact OE1-NZ 3.39Å; E32-K36 IonicContact OE1-NZ 2.76Å; E32-K36 WeakPolarHBondContact OE1-CE 3.38Å; E32-K36 PolarHBondContact O-N 2.69Å; E32-K36 WeakPolarHBondContact O-CG 3.49Å; V34-K36 PolarHBondContact O-N 2.95Å
37	N	97	Very high	96.2	Very high	142 Å²	142	133.5 Å²	133.5	76%	0.759	67%	0.667	S	S	*	*	T	Hydrogen-bonded Turn	trans	-91.6	-5.3	-177.4	-63.9	-51.8	0	0	0	113.1	E33 V34 L35	E33-N37 PolarHBondContact O-ND2 3.27Å; V34-N37 PolarHBondContact O-N 3.4Å; L35-N37 VanDerWaalsContact C-N 3.26Å; L35-N37 PolarHBondContact O-N 2.78Å
38	R	96.7	Very high	96.3	Very high	150 Å²	150	131.7 Å²	131.7	57%	0.566	66%	0.663	S	S	*	*			trans	-88.3	125.1	-172.4	-161	174.4	-146.5	167.1	6.5	111.6	V34 L35 I40	V34-R38 WeakPolarHBondContact O-CB 3.49Å; V34-R38 PolarHBondContact O-N 3.34Å; L35-R38 PolarHBondContact O-N 3.45Å; L35-R38 VanDerWaalsContact O-N 3.17Å; R38-I40 HydrophobicContact CB-CG1 4.31Å; R38-I40 HydrophobicContact CG-CG1 4.12Å; R38-I40 PolarHBondContact O-N 3.39Å; R38-I40 VanDerWaalsContact O-N 3.14Å
39	A	97	Very high	96.4	Very high	95 Å²	95	132.5 Å²	132.5	79%	0.785	65%	0.654	S	S	*	*			trans	-76.2	99.8	170.3	0	0	0	0	0	110.9
40	I	96.1	Very high	96.4	Very high	128 Å²	128	131.3 Å²	131.3	66%	0.656	65%	0.648	S	S	*	*			trans	-100.6	114.3	178.2	-56.5	173.7	0	0	0	109.4	L35 R38	L35-I40 HydrophobicContact CD2-CD1 4.15Å; R38-I40 HydrophobicContact CB-CG1 4.31Å; R38-I40 HydrophobicContact CG-CG1 4.12Å; R38-I40 PolarHBondContact O-N 3.39Å; R38-I40 VanDerWaalsContact O-N 3.14Å
41	K	96.9	Very high	96.4	Very high	196 Å²	196	137.7 Å²	137.7	85%	0.852	67%	0.672	S	S	*	*	P	Polyproline II helix	trans	-91.9	135.4	179.8	-63.2	-177.3	-177.5	178.4	0	110.9
42	K	96.5	Very high	96.3	Very high	181 Å²	181	142.7 Å²	142.7	79%	0.787	69%	0.686	S	S	*	*	P	Polyproline II helix	trans	-74.1	134.4	173.8	-170.4	-179.3	179.1	178.6	0	110.1
43	A	96.8	Very high	96.3	Very high	69 Å²	69	143.4 Å²	143.4	57%	0.57	69%	0.69	S	S	*	*	P	Polyproline II helix	trans	-70.5	145.4	171	0	0	0	0	0	111.1
44	K	94.8	Very high	96.2	Very high	205 Å²	205	143.2 Å²	143.2	89%	0.891	69%	0.691	S	S	*	*	P	Polyproline II helix	trans	-62	140.1	167.9	-172.7	176.5	177	-176.7	0	108.8
45	R	92.3	Very high	96.1	Very high	271 Å²	271	149.5 Å²	149.5	100%	1.023	71%	0.714	S	S	*	*			trans	-91.8	0	173.9	-65.6	-62.9	-167.5	-152.2	1.4	109.8

Retrieved 45 of 45 residues in 12.4 ms (Link to these results)

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