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Isoform 2 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform AlphaSync

Canonical isoform description: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment.

AlphaFold DB , UniProt , Accession Q16537-2 (canonical: Q16537), Species HUMAN (Homo sapiens, Human), Gene PPP2R5E, Length 462 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure AlphaSync Parameters PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	39.7	Very low	39.6	Very low	247 Å²	247	133.3 Å²	133.3	100%	1.217	85%	0.847	S	S	*	*				0	120.4	0	-65.5	-179	96.4	0	0	106.8
2	S	36.9	Very low	39.7	Very low	128 Å²	128	132.5 Å²	132.5	90%	0.895	83%	0.831	S	S	*	*			trans	-73.5	143.1	-165.5	-59.4	0	0	0	0	114.5
3	S	39.2	Very low	39.6	Very low	122 Å²	122	136.4 Å²	136.4	85%	0.853	83%	0.829	S	S	*	*			trans	-161.7	128.3	137.8	42.9	0	0	0	0	109.2
4	A	40.8	Very low	39.5	Very low	90 Å²	90	136.9 Å²	136.9	74%	0.744	83%	0.832	S	S	*	*	P	Polyproline II helix	trans	-70.7	163.8	-162.6	0	0	0	0	0	115.7
5	P	43.3	Very low	39.5	Very low	128 Å²	128	138.5 Å²	138.5	83%	0.831	83%	0.833	S	S	*	*	P	Polyproline II helix	trans	-84.2	119.8	169.2	32.5	-27.3	0	0	0	110.5
6	T	40.5	Very low	39.1	Very low	136 Å²	136	133 Å²	133	83%	0.834	81%	0.814	S	S	*	*	P	Polyproline II helix	trans	-84.1	118.7	168.5	32.3	0	0	0	0	110.6
7	T	36.8	Very low	39	Very low	139 Å²	139	136.9 Å²	136.9	85%	0.853	82%	0.818	S	S	*	*	P	Polyproline II helix	trans	-77.2	134.3	159.8	34.8	0	0	0	0	110.3
8	P	45.2	Very low	38.8	Very low	118 Å²	118	135.2 Å²	135.2	77%	0.766	81%	0.814	S	S	*	*			trans	-117.1	162.7	164.8	37.9	-24.6	0	0	0	111.1
9	P	37.8	Very low	38.8	Very low	109 Å²	109	140.3 Å²	140.3	71%	0.708	82%	0.817	S	S	*	*				-108.7	162.9	-108.1	24.8	-6.1	0	0	0	114.3	V11	P9-V11 PolarHBondContact O-N 2.99Å
10	S	33.1	Very low	38.8	Very low	112 Å²	112	142.8 Å²	142.8	78%	0.783	82%	0.817	S	S	*	*			trans	-58.7	117.2	163.8	50.2	0	0	0	0	110.7
11	V	42	Very low	38.8	Very low	137 Å²	137	140.8 Å²	140.8	83%	0.83	81%	0.812	S	S	*	*			trans	-99.6	97.5	172.8	-172.1	0	0	0	0	108.5	P9	P9-V11 PolarHBondContact O-N 2.99Å
12	D	40.9	Very low	38.5	Very low	124 Å²	124	135 Å²	135	66%	0.663	79%	0.791	S	S	*	*			trans	-62	138.4	161.5	-94.2	-54.9	0	0	0	111.1
13	K	38.2	Very low	38.6	Very low	183 Å²	183	140.4 Å²	140.4	80%	0.796	79%	0.791	S	S	*	*			trans	51.9	96.1	144.5	-62.2	175.4	-179.7	174.8	0	118.2
14	V	39	Very low	38.5	Very low	144 Å²	144	144.1 Å²	144.1	87%	0.873	79%	0.792	S	S	*	*				-158.6	105.6	128.5	-165.2	0	0	0	0	109
15	D	38.9	Very low	38.5	Very low	160 Å²	160	144.4 Å²	144.4	86%	0.856	79%	0.794	S	S	*	*			trans	-145.2	124.1	134.4	-141.4	-12.8	0	0	0	110
16	G	34.2	Very low	38.2	Very low	51 Å²	51	148.1 Å²	148.1	53%	0.526	79%	0.792	S	S	.	*			trans	-108.4	101	-162.1	0	0	0	0	0	111.2
17	F	36.4	Very low	38	Very low	199 Å²	199	151.4 Å²	151.4	87%	0.873	80%	0.798	S	S	*	*			trans	-148.8	55.3	153.8	-86.1	-76.3	0	0	0	110.8
18	S	35.5	Very low	38.4	Very low	107 Å²	107	152.2 Å²	152.2	75%	0.748	79%	0.789	S	S	*	*			trans	-91.8	94.7	159.9	-171	0	0	0	0	109.5
19	R	38.7	Very low	38.2	Very low	232 Å²	232	157.3 Å²	157.3	88%	0.875	79%	0.793	S	S	*	*			trans	-115.7	59.9	162.3	-81.8	-169.1	-175	172.9	3.3	109.7
20	K	39.2	Very low	38.8	Very low	189 Å²	189	154.2 Å²	154.2	82%	0.822	78%	0.775	S	S	*	*			trans	-134.4	69.6	148.7	-76.9	-170.2	-179.4	176.7	0	108.4
21	S	38	Very low	39.6	Very low	102 Å²	102	156 Å²	156	71%	0.713	77%	0.77	S	S	*	*			trans	-73	136	174.5	85.2	0	0	0	0	110.6
22	V	34.5	Very low	39.9	Very low	126 Å²	126	152.3 Å²	152.3	76%	0.764	75%	0.751	S	S	*	*			trans	68.4	75.9	151.8	-162.5	0	0	0	0	115.7
23	R	37.8	Very low	40.6	Very low	241 Å²	241	147.8 Å²	147.8	91%	0.909	73%	0.729	S	S	*	*			trans	-117	106.8	138.5	-76.8	-174	175.3	176.7	0.6	108	A25	R23-A25 PolarHBondContact O-N 3.27Å
24	K	38.4	Very low	41.2	Very low	199 Å²	199	143.3 Å²	143.3	87%	0.865	72%	0.72	S	S	*	*			trans	-54.2	104.6	158.8	-89.8	178.8	170.9	176.9	0	106.9	R26	K24-R26 PolarHBondContact O-N 3.28Å
25	A	40.7	Very low	42.1	Very low	96 Å²	96	140.9 Å²	140.9	79%	0.793	70%	0.7	S	S	*	*			trans	-59.5	110	165.8	0	0	0	0	0	106.9	R23 Q27	R23-A25 PolarHBondContact O-N 3.27Å; A25-Q27 PolarHBondContact O-N 3.32Å
26	R	36.3	Very low	43	Very low	207 Å²	207	135.9 Å²	135.9	78%	0.781	67%	0.67	S	S	*	*			trans	-60.5	120.5	168.2	-84	169	78	172.8	4.8	105.9	K24 K28	K24-R26 PolarHBondContact O-N 3.28Å; R26-K28 VanDerWaalsContact C-N 3.33Å; R26-K28 HydrophobicContact CB-CG 4.39Å; R26-K28 PolarHBondContact O-N 3.43Å
27	Q	37.4	Very low	43.5	Very low	204 Å²	204	143.9 Å²	143.9	95%	0.953	69%	0.685	S	S	*	*			trans	-48.7	102.2	159.3	-82.9	177	-29.4	0	0	107.6	A25	A25-Q27 PolarHBondContact O-N 3.32Å
28	K	45.5	Very low	43.9	Very low	156 Å²	156	139.6 Å²	139.6	68%	0.678	68%	0.679	S	S	*	*			trans	-105	133.9	174.1	-86	-176.3	176.6	178.4	0	107.2	R26 S30	R26-K28 VanDerWaalsContact C-N 3.33Å; R26-K28 HydrophobicContact CB-CG 4.39Å; R26-K28 PolarHBondContact O-N 3.43Å; K28-S30 PolarHBondContact O-N 2.87Å
29	R	40.9	Very low	44.5	Very low	225 Å²	225	141.9 Å²	141.9	85%	0.849	68%	0.678	S	S	*	*	P	Polyproline II helix	trans	-51.6	124	-179.4	-76.3	172.4	157.2	175.1	-8.9	110	Q31 M77	R29-Q31 PolarHBondContact O-N 3.12Å; R29-M77 HydrophobicContact CB-CE 4.41Å
30	S	49.9	Very low	45	Very low	45 Å²	45	134.9 Å²	134.9	32%	0.315	68%	0.678	S	S	.	*	P	Polyproline II helix	trans	-51.5	137.3	165.7	41.3	0	0	0	0	109.4	K28 S32 M77	K28-S30 PolarHBondContact O-N 2.87Å; S30-S32 PolarHBondContact O-N 2.97Å; S30-M77 WeakPolarHBondContact O-CE 3.37Å; S30-M77 WeakPolarHBondContact OG-CE 3.45Å; S30-M77 PolarHBondContact OG-SD 3.41Å
31	Q	50	Low	45.8	Very low	149 Å²	149	133.9 Å²	133.9	70%	0.696	67%	0.674	S	S	*	*	P	Polyproline II helix	trans	-73.7	126.7	179.5	-67.8	-170	9.8	0	0	109.4	R29 S33	R29-Q31 PolarHBondContact O-N 3.12Å; Q31-S33 PolarHBondContact O-N 2.92Å
32	S	48.4	Very low	47	Very low	60 Å²	60	133.7 Å²	133.7	42%	0.42	67%	0.67	S	S	.	*	P	Polyproline II helix	trans	-57	132.1	176.5	-178.4	0	0	0	0	110.6	S30 F36	S30-S32 PolarHBondContact O-N 2.97Å; S32-F36 WeakPolarHBondContact OG-CD2 3.37Å
33	S	54.4	Low	48.7	Very low	28 Å²	28	129.4 Å²	129.4	20%	0.196	64%	0.642	C	S	.	*	P	Polyproline II helix	trans	-62.3	149.5	177.4	84.8	0	0	0	0	110.8	Q31 Q35 F36	Q31-S33 PolarHBondContact O-N 2.92Å; S33-Q35 PolarHBondContact O-N 3.43Å; S33-Q35 PolarHBondContact OG-N 3.27Å; S33-F36 VanDerWaalsContact O-CD2 3.29Å; S33-F36 WeakPolarHBondContact O-CD2 3.41Å; S33-F36 PolarHBondContact O-N 2.92Å; S33-F36 VanDerWaalsContact O-N 3.12Å; S33-F36 WeakPolarHBondContact OG-CD2 3.12Å; S33-F36 WeakPolarHBondContact OG-CE2 3.3Å
34	S	51.9	Low	50.3	Low	89 Å²	89	125.5 Å²	125.5	62%	0.622	63%	0.634	S	S	*	*	G	3₁₀ helix	trans	-61.1	-14.9	178.7	60.5	0	0	0	0	113.6	F36 R37	S34-F36 PolarHBondContact O-N 2.76Å; S34-R37 PolarHBondContact O-N 3.2Å
35	Q	56.9	Low	52.4	Low	94 Å²	94	116.7 Å²	116.7	44%	0.439	60%	0.597	S	S	.	*	G	3₁₀ helix	trans	-65.8	-22	176.9	-65.7	-179.6	-17.7	0	0	112.6	S33 R37 F124	S33-Q35 PolarHBondContact O-N 3.43Å; S33-Q35 PolarHBondContact OG-N 3.27Å; Q35-R37 VanDerWaalsContact C-N 3.32Å; Q35-R37 PolarHBondContact O-N 2.89Å; Q35-F124 PolarHBondContact NE2-O 2.67Å
36	F	57.4	Low	54.5	Low	54 Å²	54	116.7 Å²	116.7	24%	0.237	59%	0.587	C	S	.	*	G	3₁₀ helix	trans	-84	-0.5	-179.5	-58.3	-64.6	0	0	0	114.1	S32 S33 S34 S38 I73 F74 D75	S32-F36 WeakPolarHBondContact OG-CD2 3.37Å; S33-F36 VanDerWaalsContact O-CD2 3.29Å; S33-F36 WeakPolarHBondContact O-CD2 3.41Å; S33-F36 PolarHBondContact O-N 2.92Å; S33-F36 VanDerWaalsContact O-N 3.12Å; S33-F36 WeakPolarHBondContact OG-CD2 3.12Å; S33-F36 WeakPolarHBondContact OG-CE2 3.3Å; S34-F36 PolarHBondContact O-N 2.76Å; F36-S38 PolarHBondContact O-N 3.18Å; F36-I73 HydrophobicContact CE1-CG2 3.73Å; F36-I73 HydrophobicContact CZ-CG2 4.31Å; F36-F74 VanDerWaalsContact CE1-O 3.23Å; F36-F74 WeakPolarHBondContact CE1-O 3.46Å; F36-D75 HydrophobicContact CB-CB 4.41Å; F36-D75 HydrophobicContact CD1-CB 3.6Å; F36-D75 VanDerWaalsContact CE1-CA 3.42Å; F36-D75 HydrophobicContact CE1-CB 3.99Å; F36-D75 HydrophobicContact CG-CB 4.01Å
37	R	46	Very low	57	Low	220 Å²	220	111.9 Å²	111.9	83%	0.83	58%	0.582	S	S	*	*			trans	-63.9	103.4	-177.4	-88.2	-173	177.4	178.5	1.1	112	S34 Q35	S34-R37 PolarHBondContact O-N 3.2Å; Q35-R37 VanDerWaalsContact C-N 3.32Å; Q35-R37 PolarHBondContact O-N 2.89Å
38	S	43.4	Very low	59.7	Low	108 Å²	108	103.9 Å²	103.9	76%	0.755	55%	0.546	S	S	*	.			trans	69.1	70.2	149.7	173.8	0	0	0	0	116.1	F36	F36-S38 PolarHBondContact O-N 3.18Å
39	Q	48	Very low	61.9	Low	156 Å²	156	99.7 Å²	99.7	73%	0.729	54%	0.535	S	S	*	.			trans	-105.9	90.9	140.3	-66.4	-165.6	12.1	0	0	107.7	K41	Q39-K41 PolarHBondContact O-N 3.47Å
40	G	50	Low	64.4	Low	84 Å²	84	92.1 Å²	92.1	87%	0.866	51%	0.511	S	S	*	.			trans	-67.3	20.1	175	0	0	0	0	0	114.4
41	K	56.2	Low	66.5	Low	169 Å²	169	90.2 Å²	90.2	74%	0.735	50%	0.497	S	S	*	.	S	Bend	trans	-120.3	139.3	173.4	-72.7	-173.5	178.2	-177.5	0	108.3	Q39 I43	Q39-K41 PolarHBondContact O-N 3.47Å; K41-I43 PolarHBondContact O-N 3.42Å
42	P	62.5	Low	68.4	Low	98 Å²	98	91 Å²	91	64%	0.636	50%	0.498	S	S	*	.			trans	-55.5	130.4	173.7	22.6	-30.7	0	0	0	109.3	E44	P42-E44 PolarHBondContact O-N 2.84Å
43	I	70.4	Confident	70.5	Confident	35 Å²	35	93.4 Å²	93.4	18%	0.179	51%	0.506	C	S	.	.			trans	-75.4	106.3	177.8	-65.6	176	0	0	0	107.2	K41 V72 F74 M85	K41-I43 PolarHBondContact O-N 3.42Å; I43-V72 HydrophobicContact CD1-CG1 4.24Å; I43-V72 HydrophobicContact CG2-CG1 3.3Å; I43-F74 HydrophobicContact CB-CE1 4.05Å; I43-F74 HydrophobicContact CG2-CE1 3.82Å; I43-F74 HydrophobicContact CG2-CZ 4.03Å; I43-M85 WeakPolarHBondContact O-CG 3.29Å
44	E	71.8	Confident	72.3	Confident	159 Å²	159	93.1 Å²	93.1	74%	0.743	50%	0.503	S	S	*	.			trans	-98	113	175.1	-72.1	-171.4	165.5	0	0	110.8	P42	P42-E44 PolarHBondContact O-N 2.84Å
45	L	82.2	Confident	74.2	Confident	15 Å²	15	92.3 Å²	92.3	8%	0.079	50%	0.496	C	S	.	.	P	Polyproline II helix	trans	-82.4	129.8	169	-66.7	175.5	0	0	0	109.4	P47 Q69 V72 F74 M85 Y88 K89	L45-P47 VanDerWaalsContact O-CD 3.29Å; L45-P47 WeakPolarHBondContact O-CD 3.29Å; L45-Q69 HydrophobicContact CD2-CB 4.34Å; L45-V72 HydrophobicContact CD2-CB 4Å; L45-V72 HydrophobicContact CD2-CG1 4.28Å; L45-V72 HydrophobicContact CD2-CG2 3.82Å; L45-F74 HydrophobicContact CD1-CE2 3.95Å; L45-F74 HydrophobicContact CD1-CZ 3.69Å; L45-F74 HydrophobicContact CG-CZ 4.12Å; L45-M85 HydrophobicContact CB-SD 4.03Å; L45-Y88 HydrophobicContact CB-CD1 3.83Å; L45-Y88 HydrophobicContact CB-CE1 3.87Å; L45-Y88 HydrophobicContact CD1-CD1 3.73Å; L45-Y88 HydrophobicContact CD1-CE1 4.21Å; L45-Y88 HydrophobicContact CG-CD1 4.45Å; L45-K89 HydrophobicContact CD1-CB 4.12Å
46	T	86.2	Confident	75.8	Confident	96 Å²	96	92.3 Å²	92.3	59%	0.589	51%	0.506	S	S	*	.	P	Polyproline II helix	trans	-67.8	120.5	174.5	-50.9	0	0	0	0	110.1	L48 Q69 Y88	T46-L48 PolarHBondContact O-N 3.4Å; T46-Q69 PolarHBondContact O-NE2 2.74Å; T46-Q69 PolarHBondContact O-OE1 3.31Å; T46-Y88 PolarHBondContact O-OH 2.76Å
47	P	88.8	Confident	77.4	Confident	105 Å²	105	94.5 Å²	94.5	68%	0.682	53%	0.529	S	S	*	.	P	Polyproline II helix	trans	-59.5	126.6	175.9	-24.5	35.6	0	0	0	111.6	L45 Y88	L45-P47 VanDerWaalsContact O-CD 3.29Å; L45-P47 WeakPolarHBondContact O-CD 3.29Å; P47-Y88 WeakPolarHBondContact CA-OH 3.3Å; P47-Y88 HydrophobicContact CB-CE2 4.42Å
48	L	92.1	Very high	79.6	Confident	36 Å²	36	89.1 Å²	89.1	19%	0.188	51%	0.513	C	S	.	.			trans	-108.8	146.7	176.8	-66.7	178.7	0	0	0	109.5	T46 L62 K65 K66 Q69 Y88	T46-L48 PolarHBondContact O-N 3.4Å; L48-L62 HydrophobicContact CB-CD1 4.03Å; L48-L62 HydrophobicContact CD1-CD1 4.29Å; L48-L62 HydrophobicContact CD2-CD1 4.49Å; L48-K65 HydrophobicContact CD1-CB 3.88Å; L48-K66 HydrophobicContact CB-CG 4.45Å; L48-K66 HydrophobicContact CD1-CG 3.71Å; L48-Q69 VanDerWaalsContact CD1-CD 3.41Å; L48-Q69 HydrophobicContact CD1-CG 4.22Å; L48-Y88 PolarHBondContact N-OH 2.73Å
49	P	93.4	Very high	81.9	Confident	69 Å²	69	85.4 Å²	85.4	45%	0.448	48%	0.483	S	S	.	.			trans	-59.4	159.8	176.5	25.8	-33.9	0	0	0	111.5	V54 L62 K66	P49-V54 HydrophobicContact CB-CG1 4Å; P49-V54 HydrophobicContact CG-CG1 3.91Å; P49-L62 HydrophobicContact CG-CD1 4.04Å; P49-L62 HydrophobicContact CG-CD2 3.95Å; P49-K66 WeakPolarHBondContact O-CE 3.43Å; P49-K66 PolarHBondContact O-NZ 3.01Å
50	L	93.6	Very high	84	Confident	66 Å²	66	80.1 Å²	80.1	35%	0.346	46%	0.463	S	S	.	.			trans	-72.2	143.3	173.3	-56.9	174.8	0	0	0	109.7	K52 D53 E95	L50-K52 HydrophobicContact CB-CG 4.03Å; L50-K52 PolarHBondContact O-N 3.27Å; L50-D53 HydrophobicContact CB-CB 4.38Å; L50-D53 WeakPolarHBondContact CB-OD2 3.36Å; L50-D53 PolarHBondContact O-N 3.04Å; L50-E95 WeakPolarHBondContact CA-OE1 3.4Å; L50-E95 WeakPolarHBondContact CB-OE1 3.46Å
51	L	92.3	Very high	86.1	Confident	4 Å²	4	81.7 Å²	81.7	2%	0.021	45%	0.447	C	S	.	.	G	3₁₀ helix	trans	-58.2	-34.3	178.1	-78.5	161	0	0	0	111.9	D53 V54 Q59 L62 F63 K66 E95 L96 Y99	L51-D53 VanDerWaalsContact C-N 3.27Å; L51-D53 PolarHBondContact O-N 3.48Å; L51-V54 WeakPolarHBondContact O-CG2 3Å; L51-Q59 HydrophobicContact CD2-CB 4.15Å; L51-Q59 HydrophobicContact CD2-CG 4.42Å; L51-Q59 WeakPolarHBondContact CD2-O 3.3Å; L51-Q59 WeakPolarHBondContact O-CG 3.44Å; L51-Q59 PolarHBondContact O-NE2 3.01Å; L51-L62 HydrophobicContact CD2-CB 4.08Å; L51-L62 HydrophobicContact CD2-CD2 3.94Å; L51-L62 HydrophobicContact CD2-CG 3.98Å; L51-L62 HydrophobicContact CG-CD2 4.28Å; L51-F63 HydrophobicContact CD1-CD2 4.23Å; L51-F63 HydrophobicContact CD2-CB 4.2Å; L51-K66 HydrophobicContact CD1-CD 4.02Å; L51-K66 HydrophobicContact CG-CD 4.08Å; L51-E95 HydrophobicContact CD1-CG 4.17Å; L51-E95 PolarHBondContact N-OE1 3.03Å; L51-L96 HydrophobicContact CD1-CD2 4.48Å; L51-Y99 HydrophobicContact CB-CD2 4.1Å; L51-Y99 HydrophobicContact CB-CE2 4.45Å; L51-Y99 HydrophobicContact CD1-CD1 4.07Å; L51-Y99 HydrophobicContact CD1-CD2 3.93Å; L51-Y99 HydrophobicContact CD1-CG 3.66Å; L51-Y99 HydrophobicContact CD2-CD2 4.44Å; L51-Y99 HydrophobicContact CD2-CE2 4.3Å; L51-Y99 HydrophobicContact CG-CD2 4.38Å
52	K	91.4	Very high	87.9	Confident	165 Å²	165	74.3 Å²	74.3	72%	0.717	42%	0.416	S	S	*	.	G	3₁₀ helix	trans	-71.2	-19.6	176.2	66	175.7	-174	-175.9	0	114	L50	L50-K52 HydrophobicContact CB-CG 4.03Å; L50-K52 PolarHBondContact O-N 3.27Å
53	D	92.3	Very high	89.5	Confident	111 Å²	111	69.6 Å²	69.6	59%	0.594	39%	0.386	S	S	*	.	G	3₁₀ helix	trans	-95	-7.2	-175.2	-62.5	-22.8	0	0	0	112.3	L50 L51	L50-D53 HydrophobicContact CB-CB 4.38Å; L50-D53 WeakPolarHBondContact CB-OD2 3.36Å; L50-D53 PolarHBondContact O-N 3.04Å; L51-D53 VanDerWaalsContact C-N 3.27Å; L51-D53 PolarHBondContact O-N 3.48Å
54	V	92.1	Very high	90.7	Very high	22 Å²	22	69.1 Å²	69.1	13%	0.133	38%	0.383	C	S	.	.	S	Bend	trans	-106.5	150.4	177.5	-58.1	0	0	0	0	111.9	P49 L51 E58 Q59 L62	P49-V54 HydrophobicContact CB-CG1 4Å; P49-V54 HydrophobicContact CG-CG1 3.91Å; L51-V54 WeakPolarHBondContact O-CG2 3Å; V54-E58 HydrophobicContact CB-CB 4.44Å; V54-E58 HydrophobicContact CG2-CB 4.49Å; V54-Q59 HydrophobicContact CG2-CB 4.49Å; V54-Q59 HydrophobicContact CG2-CG 3.61Å; V54-Q59 PolarHBondContact O-NE2 2.84Å; V54-L62 HydrophobicContact CB-CD2 4.41Å; V54-L62 HydrophobicContact CG1-CD2 3.9Å; V54-L62 HydrophobicContact CG2-CD2 3.6Å
55	P	92.3	Very high	91.8	Very high	73 Å²	73	65.9 Å²	65.9	47%	0.474	37%	0.367	S	S	.	.			trans	-55.7	146	175.2	-23.5	33.7	0	0	0	112.1	S57 E58 Q59	P55-S57 PolarHBondContact O-N 2.7Å; P55-E58 PolarHBondContact O-N 3.19Å; P55-Q59 PolarHBondContact O-N 2.67Å
56	S	89.2	Confident	92.5	Very high	93 Å²	93	65.2 Å²	65.2	65%	0.65	36%	0.363	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.8	-23.9	-178.5	-54	0	0	0	0	114.2	P60	S56-P60 WeakPolarHBondContact O-CD 3.35Å
57	S	90.9	Very high	93.1	Very high	101 Å²	101	60.7 Å²	60.7	71%	0.706	34%	0.335	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.6	-28.3	174.4	51.2	0	0	0	0	114.1	P55	P55-S57 PolarHBondContact O-N 2.7Å
58	E	92.2	Very high	93.4	Very high	107 Å²	107	59.9 Å²	59.9	50%	0.5	32%	0.322	S	S	.	.	T	Hydrogen-bonded Turn	trans	-95.9	-18.4	-178	-65.6	179.4	-158.6	0	0	112.6	V54 P55 P60 E61 L62	V54-E58 HydrophobicContact CB-CB 4.44Å; V54-E58 HydrophobicContact CG2-CB 4.49Å; P55-E58 PolarHBondContact O-N 3.19Å; E58-P60 VanDerWaalsContact C-CD 3.49Å; E58-E61 PolarHBondContact O-N 2.67Å; E58-L62 PolarHBondContact O-N 3.27Å; E58-L62 VanDerWaalsContact O-N 3.11Å
59	Q	92.9	Very high	93.5	Very high	29 Å²	29	59.6 Å²	59.6	14%	0.136	32%	0.32	C	S	.	.	H	α-helix	trans	-55.3	-41.8	-178.8	-68.3	177.9	0.8	0	0	114	L51 V54 P55 E61 L62 F63 Y99	L51-Q59 HydrophobicContact CD2-CB 4.15Å; L51-Q59 HydrophobicContact CD2-CG 4.42Å; L51-Q59 WeakPolarHBondContact CD2-O 3.3Å; L51-Q59 WeakPolarHBondContact O-CG 3.44Å; L51-Q59 PolarHBondContact O-NE2 3.01Å; V54-Q59 HydrophobicContact CG2-CB 4.49Å; V54-Q59 HydrophobicContact CG2-CG 3.61Å; V54-Q59 PolarHBondContact O-NE2 2.84Å; P55-Q59 PolarHBondContact O-N 2.67Å; Q59-E61 PolarHBondContact O-N 3.29Å; Q59-L62 PolarHBondContact O-N 3.49Å; Q59-F63 VanDerWaalsContact O-CB 3.25Å; Q59-F63 WeakPolarHBondContact O-CB 3.33Å; Q59-F63 PolarHBondContact O-N 3.07Å; Q59-Y99 HydrophobicContact CB-CE2 4.2Å; Q59-Y99 WeakPolarHBondContact CB-OH 3.47Å; Q59-Y99 PolarHBondContact OE1-OH 3.07Å
60	P	92	Very high	93.6	Very high	45 Å²	45	56.4 Å²	56.4	29%	0.292	30%	0.299	S	S	.	.	H	α-helix	trans	-61.3	-42.7	179.6	-25.2	35.7	0	0	0	113.3	S56 E58 F63 L64	S56-P60 WeakPolarHBondContact O-CD 3.35Å; E58-P60 VanDerWaalsContact C-CD 3.49Å; P60-F63 WeakPolarHBondContact O-CB 3.49Å; P60-F63 PolarHBondContact O-N 3.13Å; P60-L64 WeakPolarHBondContact O-CG 3.38Å; P60-L64 PolarHBondContact O-N 2.79Å
61	E	93.2	Very high	93.7	Very high	117 Å²	117	54 Å²	54	55%	0.547	29%	0.288	S	S	.	.	H	α-helix	trans	-68.8	-41.8	178.7	-168.8	-170.9	151.7	0	0	111.1	E58 Q59 F63 L64 K65	E58-E61 PolarHBondContact O-N 2.67Å; Q59-E61 PolarHBondContact O-N 3.29Å; E61-F63 VanDerWaalsContact C-N 3.3Å; E61-F63 PolarHBondContact O-N 2.82Å; E61-L64 PolarHBondContact O-N 2.84Å; E61-K65 WeakPolarHBondContact O-CG 3.36Å; E61-K65 PolarHBondContact O-N 3.22Å; E61-K65 VanDerWaalsContact O-N 3.07Å; E61-K65 WeakPolarHBondContact OE1-CE 3.5Å; E61-K65 IonicContact OE1-NZ 3.2Å; E61-K65 PolarHBondContact OE1-NZ 2.78Å
62	L	94.9	Very high	93.8	Very high	14 Å²	14	56.1 Å²	56.1	7%	0.073	30%	0.301	C	S	.	.	H	α-helix	trans	-62.7	-38.8	175.9	-178.4	60.3	0	0	0	111.8	L48 P49 L51 V54 E58 Q59 K65 K66	L48-L62 HydrophobicContact CB-CD1 4.03Å; L48-L62 HydrophobicContact CD1-CD1 4.29Å; L48-L62 HydrophobicContact CD2-CD1 4.49Å; P49-L62 HydrophobicContact CG-CD1 4.04Å; P49-L62 HydrophobicContact CG-CD2 3.95Å; L51-L62 HydrophobicContact CD2-CB 4.08Å; L51-L62 HydrophobicContact CD2-CD2 3.94Å; L51-L62 HydrophobicContact CD2-CG 3.98Å; L51-L62 HydrophobicContact CG-CD2 4.28Å; V54-L62 HydrophobicContact CB-CD2 4.41Å; V54-L62 HydrophobicContact CG1-CD2 3.9Å; V54-L62 HydrophobicContact CG2-CD2 3.6Å; E58-L62 PolarHBondContact O-N 3.27Å; E58-L62 VanDerWaalsContact O-N 3.11Å; Q59-L62 PolarHBondContact O-N 3.49Å; L62-K65 PolarHBondContact O-N 2.89Å; L62-K66 HydrophobicContact CG-CD 4.34Å; L62-K66 WeakPolarHBondContact O-CG 3.46Å; L62-K66 PolarHBondContact O-N 2.95Å
63	F	95.5	Very high	93.8	Very high	0 Å²	0	50.6 Å²	50.6	0%	0	28%	0.279	C	S	.	.	H	α-helix	trans	-60	-46.3	176	-178.3	-120.5	0	0	0	111.2	L51 Q59 P60 E61 K65 K66 L67 L96 Y99 T111 F157	L51-F63 HydrophobicContact CD1-CD2 4.23Å; L51-F63 HydrophobicContact CD2-CB 4.2Å; Q59-F63 VanDerWaalsContact O-CB 3.25Å; Q59-F63 WeakPolarHBondContact O-CB 3.33Å; Q59-F63 PolarHBondContact O-N 3.07Å; P60-F63 WeakPolarHBondContact O-CB 3.49Å; P60-F63 PolarHBondContact O-N 3.13Å; E61-F63 VanDerWaalsContact C-N 3.3Å; E61-F63 PolarHBondContact O-N 2.82Å; F63-K65 PolarHBondContact O-N 2.89Å; F63-K66 PolarHBondContact O-N 3.45Å; F63-L67 HydrophobicContact CD1-CD1 4.09Å; F63-L67 HydrophobicContact CE1-CD1 3.84Å; F63-L67 HydrophobicContact CZ-CD1 4.11Å; F63-L67 HydrophobicContact CZ-CG 4.47Å; F63-L67 WeakPolarHBondContact O-CG 3.31Å; F63-L67 PolarHBondContact O-N 3.32Å; F63-L96 HydrophobicContact CD2-CD2 3.29Å; F63-L96 HydrophobicContact CE2-CB 4.33Å; F63-L96 HydrophobicContact CE2-CD2 3.28Å; F63-L96 HydrophobicContact CE2-CG 4.38Å; F63-L96 HydrophobicContact CG-CD2 4.48Å; F63-L96 HydrophobicContact CZ-CD2 4.47Å; F63-Y99 HydrophobicContact CB-CD1 4.49Å; F63-Y99 HydrophobicContact CB-CE1 4.06Å; F63-Y99 HydrophobicContact CD1-CE1 4.26Å; F63-Y99 AromaticContact CD2-CD1 3.44Å; F63-Y99 HydrophobicContact CD2-CD1 3.44Å; F63-Y99 VanDerWaalsContact CD2-CD1 3.44Å; F63-Y99 AromaticContact CD2-CE1 3.81Å; F63-Y99 HydrophobicContact CD2-CE1 3.81Å; F63-Y99 HydrophobicContact CD2-CG 4.42Å; F63-Y99 AromaticContact CE2-CD1 3.63Å; F63-Y99 HydrophobicContact CE2-CD1 3.63Å; F63-Y99 HydrophobicContact CE2-CE1 4.29Å; F63-Y99 AromaticContact CG-CD1 3.94Å; F63-Y99 HydrophobicContact CG-CD1 3.94Å; F63-Y99 AromaticContact CG-CE1 3.8Å; F63-Y99 HydrophobicContact CG-CE1 3.8Å; F63-Y99 HydrophobicContact CZ-CD1 4.26Å; F63-T111 HydrophobicContact CD1-CG2 4.16Å; F63-T111 HydrophobicContact CE1-CG2 3.58Å; F63-F157 HydrophobicContact CE2-CE2 4.12Å; F63-F157 HydrophobicContact CE2-CZ 4.38Å; F63-F157 AromaticContact CZ-CE2 3.9Å; F63-F157 HydrophobicContact CZ-CE2 3.9Å; F63-F157 AromaticContact CZ-CZ 3.83Å; F63-F157 HydrophobicContact CZ-CZ 3.83Å
64	L	95.6	Very high	93.8	Very high	25 Å²	25	45.4 Å²	45.4	13%	0.131	25%	0.251	C	S	.	.	H	α-helix	trans	-60.8	-43.8	175	-63	175.9	0	0	0	112	P60 E61 K66 L67 Q68 Q110 E114	P60-L64 WeakPolarHBondContact O-CG 3.38Å; P60-L64 PolarHBondContact O-N 2.79Å; E61-L64 PolarHBondContact O-N 2.84Å; L64-K66 VanDerWaalsContact C-N 3.35Å; L64-K66 PolarHBondContact O-N 2.85Å; L64-L67 HydrophobicContact CD2-CD1 4.47Å; L64-L67 WeakPolarHBondContact O-CB 3.46Å; L64-L67 PolarHBondContact O-N 3.41Å; L64-Q68 WeakPolarHBondContact O-CG 3.28Å; L64-Q68 PolarHBondContact O-N 3.26Å; L64-Q110 HydrophobicContact CD1-CB 4.34Å; L64-E114 HydrophobicContact CD2-CB 4.17Å; L64-E114 HydrophobicContact CD2-CG 4.05Å
65	K	95.5	Very high	93.5	Very high	90 Å²	90	46.4 Å²	46.4	39%	0.391	26%	0.256	S	S	.	.	H	α-helix	trans	-61.6	-41.4	176.7	-71.4	175	-175.6	165.6	0	112.1	L48 E61 L62 F63 Q68 Q69	L48-K65 HydrophobicContact CD1-CB 3.88Å; E61-K65 WeakPolarHBondContact O-CG 3.36Å; E61-K65 PolarHBondContact O-N 3.22Å; E61-K65 VanDerWaalsContact O-N 3.07Å; E61-K65 WeakPolarHBondContact OE1-CE 3.5Å; E61-K65 IonicContact OE1-NZ 3.2Å; E61-K65 PolarHBondContact OE1-NZ 2.78Å; L62-K65 PolarHBondContact O-N 2.89Å; F63-K65 PolarHBondContact O-N 2.89Å; K65-Q68 WeakPolarHBondContact O-CB 3.45Å; K65-Q68 PolarHBondContact O-N 3.38Å; K65-Q69 WeakPolarHBondContact O-CG 3.44Å; K65-Q69 PolarHBondContact O-N 3.43Å
66	K	96.9	Very high	93.4	Very high	2 Å²	2	44.5 Å²	44.5	1%	0.009	24%	0.24	C	C	.	.	H	α-helix	trans	-66.2	-41.2	176.3	-74.9	176.3	-178.2	-83.9	0	112	L48 P49 L51 L62 F63 L64 Q68 Q69 C70 T92 E95 L96	L48-K66 HydrophobicContact CB-CG 4.45Å; L48-K66 HydrophobicContact CD1-CG 3.71Å; P49-K66 WeakPolarHBondContact O-CE 3.43Å; P49-K66 PolarHBondContact O-NZ 3.01Å; L51-K66 HydrophobicContact CD1-CD 4.02Å; L51-K66 HydrophobicContact CG-CD 4.08Å; L62-K66 HydrophobicContact CG-CD 4.34Å; L62-K66 WeakPolarHBondContact O-CG 3.46Å; L62-K66 PolarHBondContact O-N 2.95Å; F63-K66 PolarHBondContact O-N 3.45Å; L64-K66 VanDerWaalsContact C-N 3.35Å; L64-K66 PolarHBondContact O-N 2.85Å; K66-Q68 VanDerWaalsContact C-N 3.28Å; K66-Q68 PolarHBondContact O-N 3.22Å; K66-Q69 PolarHBondContact O-N 2.83Å; K66-C70 PolarHBondContact O-N 3.29Å; K66-C70 PolarHBondContact O-SG 2.95Å; K66-T92 HydrophobicContact CB-CG2 3.91Å; K66-T92 HydrophobicContact CD-CG2 4.24Å; K66-T92 HydrophobicContact CG-CG2 3.99Å; K66-E95 VanDerWaalsContact CE-OE2 3.3Å; K66-E95 WeakPolarHBondContact CE-OE2 3.49Å; K66-E95 IonicContact NZ-OE1 3.35Å; K66-E95 IonicContact NZ-OE2 2.76Å; K66-E95 PolarHBondContact NZ-OE2 3.46Å; K66-L96 HydrophobicContact CB-CD2 3.83Å; K66-L96 HydrophobicContact CB-CG 4.49Å; K66-L96 HydrophobicContact CD-CD2 4.47Å
67	L	97	Very high	93.2	Very high	0 Å²	0	42.6 Å²	42.6	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-57.8	-43.2	171.7	-72.4	170.3	0	0	0	111.2	F63 L64 C70 C71 L96 E114 V115 M118 F157	F63-L67 HydrophobicContact CD1-CD1 4.09Å; F63-L67 HydrophobicContact CE1-CD1 3.84Å; F63-L67 HydrophobicContact CZ-CD1 4.11Å; F63-L67 HydrophobicContact CZ-CG 4.47Å; F63-L67 WeakPolarHBondContact O-CG 3.31Å; F63-L67 PolarHBondContact O-N 3.32Å; L64-L67 HydrophobicContact CD2-CD1 4.47Å; L64-L67 WeakPolarHBondContact O-CB 3.46Å; L64-L67 PolarHBondContact O-N 3.41Å; L67-C70 PolarHBondContact O-N 3.42Å; L67-C71 PolarHBondContact O-N 3.28Å; L67-C71 PolarHBondContact O-SG 2.95Å; L67-C71 VanDerWaalsContact O-SG 3.41Å; L67-L96 HydrophobicContact CD2-CD1 4.03Å; L67-E114 HydrophobicContact CB-CB 4.37Å; L67-E114 HydrophobicContact CD1-CB 4.08Å; L67-V115 HydrophobicContact CD1-CG2 3.76Å; L67-V115 HydrophobicContact CD2-CG2 4.24Å; L67-M118 HydrophobicContact CD2-CB 4.4Å; L67-M118 HydrophobicContact CD2-CE 3.98Å; L67-M118 HydrophobicContact CD2-CG 4.36Å; L67-M118 WeakPolarHBondContact O-CG 3.5Å; L67-F157 HydrophobicContact CD2-CE1 3.84Å; L67-F157 HydrophobicContact CD2-CE2 4.5Å; L67-F157 HydrophobicContact CD2-CZ 3.66Å
68	Q	95.9	Very high	93	Very high	88 Å²	88	41.5 Å²	41.5	41%	0.411	21%	0.207	S	C	.	.	H	α-helix	trans	-62.6	-43.1	177.5	-71.7	170.3	-6.1	0	0	113.1	L64 K65 K66 C70 C71 E114 R117	L64-Q68 WeakPolarHBondContact O-CG 3.28Å; L64-Q68 PolarHBondContact O-N 3.26Å; K65-Q68 WeakPolarHBondContact O-CB 3.45Å; K65-Q68 PolarHBondContact O-N 3.38Å; K66-Q68 VanDerWaalsContact C-N 3.28Å; K66-Q68 PolarHBondContact O-N 3.22Å; Q68-C70 VanDerWaalsContact C-N 3.32Å; Q68-C70 PolarHBondContact O-N 3.45Å; Q68-C71 WeakPolarHBondContact O-CB 3.4Å; Q68-C71 PolarHBondContact O-N 2.99Å; Q68-E114 WeakPolarHBondContact CG-OE2 3.44Å; Q68-E114 PolarHBondContact NE2-OE1 3.22Å; Q68-R117 VanDerWaalsContact CG-NH2 3.32Å
69	Q	94	Very high	92.5	Very high	30 Å²	30	41.2 Å²	41.2	14%	0.14	21%	0.213	C	C	.	.	H	α-helix	trans	-63.6	-36.6	174.7	-73.3	-170.8	-10.5	0	0	112.8	L45 T46 L48 K65 K66 C71 V72 Y88	L45-Q69 HydrophobicContact CD2-CB 4.34Å; T46-Q69 PolarHBondContact O-NE2 2.74Å; T46-Q69 PolarHBondContact O-OE1 3.31Å; L48-Q69 VanDerWaalsContact CD1-CD 3.41Å; L48-Q69 HydrophobicContact CD1-CG 4.22Å; K65-Q69 WeakPolarHBondContact O-CG 3.44Å; K65-Q69 PolarHBondContact O-N 3.43Å; K66-Q69 PolarHBondContact O-N 2.83Å; Q69-C71 PolarHBondContact O-N 3.28Å; Q69-C71 VanDerWaalsContact O-N 3.16Å; Q69-V72 WeakPolarHBondContact O-CB 3.48Å; Q69-V72 WeakPolarHBondContact O-CG2 3.2Å; Q69-V72 PolarHBondContact O-N 3.38Å; Q69-V72 VanDerWaalsContact O-N 3.16Å; Q69-Y88 PolarHBondContact OE1-OH 3.46Å
70	C	96.6	Very high	92.1	Very high	2 Å²	2	46.4 Å²	46.4	1%	0.014	24%	0.241	C	C	.	.	T	Hydrogen-bonded Turn	trans	-69.4	-8.7	179.7	-68.2	0	0	0	0	114	K66 L67 Q68 V72 K89 L93 M118 N122	K66-C70 PolarHBondContact O-N 3.29Å; K66-C70 PolarHBondContact O-SG 2.95Å; L67-C70 PolarHBondContact O-N 3.42Å; Q68-C70 VanDerWaalsContact C-N 3.32Å; Q68-C70 PolarHBondContact O-N 3.45Å; C70-V72 PolarHBondContact O-N 3.03Å; C70-K89 WeakPolarHBondContact O-CE 3.45Å; C70-K89 PolarHBondContact O-NZ 2.75Å; C70-L93 HydrophobicContact CB-CD2 3.9Å; C70-L93 HydrophobicContact CB-CG 4.49Å; C70-M118 HydrophobicContact CB-CG 3.77Å; C70-M118 HydrophobicContact CB-SD 4.22Å; C70-N122 PolarHBondContact O-ND2 2.92Å
71	C	95.9	Very high	91.9	Very high	16 Å²	16	45.5 Å²	45.5	11%	0.108	24%	0.236	C	C	.	.	T	Hydrogen-bonded Turn	trans	-72.3	-16	171.3	-62.9	0	0	0	0	113.8	L67 Q68 Q69 I73 R117 M118 C121	L67-C71 PolarHBondContact O-N 3.28Å; L67-C71 PolarHBondContact O-SG 2.95Å; L67-C71 VanDerWaalsContact O-SG 3.41Å; Q68-C71 WeakPolarHBondContact O-CB 3.4Å; Q68-C71 PolarHBondContact O-N 2.99Å; Q69-C71 PolarHBondContact O-N 3.28Å; Q69-C71 VanDerWaalsContact O-N 3.16Å; C71-I73 PolarHBondContact O-N 3.04Å; C71-R117 PolarHBondContact SG-NH1 3Å; C71-R117 PolarHBondContact SG-NH2 3.17Å; C71-M118 VanDerWaalsContact SG-CA 3.51Å; C71-C121 HydrophobicContact CB-CB 4.31Å
72	V	93.5	Very high	91.6	Very high	48 Å²	48	42.4 Å²	42.4	29%	0.291	22%	0.223	S	C	.	.			trans	-72.6	124.7	177.7	177.9	0	0	0	0	109.5	I43 L45 Q69 C70 F74 K89	I43-V72 HydrophobicContact CD1-CG1 4.24Å; I43-V72 HydrophobicContact CG2-CG1 3.3Å; L45-V72 HydrophobicContact CD2-CB 4Å; L45-V72 HydrophobicContact CD2-CG1 4.28Å; L45-V72 HydrophobicContact CD2-CG2 3.82Å; Q69-V72 WeakPolarHBondContact O-CB 3.48Å; Q69-V72 WeakPolarHBondContact O-CG2 3.2Å; Q69-V72 PolarHBondContact O-N 3.38Å; Q69-V72 VanDerWaalsContact O-N 3.16Å; C70-V72 PolarHBondContact O-N 3.03Å; V72-F74 HydrophobicContact CG1-CE2 4.36Å; V72-F74 HydrophobicContact CG1-CZ 4.29Å; V72-K89 WeakPolarHBondContact O-CD 3.45Å; V72-K89 PolarHBondContact O-NZ 2.72Å
73	I	92.2	Very high	91.4	Very high	49 Å²	49	46.6 Å²	46.6	25%	0.251	25%	0.245	S	C	.	.			trans	-100	134.4	-175.6	-52	-54.9	0	0	0	109.4	F36 C71 C121 N122	F36-I73 HydrophobicContact CE1-CG2 3.73Å; F36-I73 HydrophobicContact CZ-CG2 4.31Å; C71-I73 PolarHBondContact O-N 3.04Å; I73-C121 WeakPolarHBondContact CD1-O 3.5Å; I73-N122 HydrophobicContact CD1-CB 4.17Å; I73-N122 VanDerWaalsContact CD1-CG 3.5Å; I73-N122 WeakPolarHBondContact CD1-OD1 3.35Å
74	F	90.5	Very high	91.2	Very high	2 Å²	2	54.6 Å²	54.6	1%	0.009	28%	0.28	C	S	.	.			trans	-108.2	140.6	179.7	-68.3	-84.3	0	0	0	110.5	F36 I43 L45 V72 F76 D82 M85 K86 K89 H150	F36-F74 VanDerWaalsContact CE1-O 3.23Å; F36-F74 WeakPolarHBondContact CE1-O 3.46Å; I43-F74 HydrophobicContact CB-CE1 4.05Å; I43-F74 HydrophobicContact CG2-CE1 3.82Å; I43-F74 HydrophobicContact CG2-CZ 4.03Å; L45-F74 HydrophobicContact CD1-CE2 3.95Å; L45-F74 HydrophobicContact CD1-CZ 3.69Å; L45-F74 HydrophobicContact CG-CZ 4.12Å; V72-F74 HydrophobicContact CG1-CE2 4.36Å; V72-F74 HydrophobicContact CG1-CZ 4.29Å; F74-F76 HydrophobicContact CB-CD2 4.48Å; F74-F76 HydrophobicContact CB-CE2 4.15Å; F74-F76 VanDerWaalsContact O-CD2 3.3Å; F74-F76 WeakPolarHBondContact O-CD2 3.47Å; F74-F76 PolarHBondContact O-N 3.19Å; F74-D82 HydrophobicContact CD1-CB 3.83Å; F74-D82 HydrophobicContact CE1-CB 4.06Å; F74-M85 HydrophobicContact CE1-CB 3.49Å; F74-M85 VanDerWaalsContact CE1-CB 3.49Å; F74-M85 HydrophobicContact CZ-CB 3.62Å; F74-K86 HydrophobicContact CB-CD 4.43Å; F74-K86 HydrophobicContact CB-CG 3.75Å; F74-K86 HydrophobicContact CD1-CG 4Å; F74-K86 HydrophobicContact CD2-CG 4.38Å; F74-K86 HydrophobicContact CG-CG 3.78Å; F74-K89 HydrophobicContact CD2-CD 3.84Å; F74-K89 HydrophobicContact CE2-CB 3.89Å; F74-K89 HydrophobicContact CE2-CD 3.66Å; F74-K89 HydrophobicContact CE2-CG 4.4Å; F74-H150 AromaticContact CD2-CE1 3.75Å
75	D	87.5	Confident	91	Very high	44 Å²	44	55 Å²	55	24%	0.235	28%	0.281	C	S	.	.			trans	-76.5	111.2	174.1	-172.5	3.7	0	0	0	110.6	F36 M77 K86	F36-D75 HydrophobicContact CB-CB 4.41Å; F36-D75 HydrophobicContact CD1-CB 3.6Å; F36-D75 VanDerWaalsContact CE1-CA 3.42Å; F36-D75 HydrophobicContact CE1-CB 3.99Å; F36-D75 HydrophobicContact CG-CB 4.01Å; D75-M77 WeakPolarHBondContact OD1-CB 3.42Å; D75-M77 WeakPolarHBondContact OD1-CG 3.41Å; D75-M77 PolarHBondContact OD1-N 2.89Å; D75-K86 WeakPolarHBondContact O-CE 3.41Å; D75-K86 PolarHBondContact O-NZ 3.44Å
76	F	89.7	Confident	90.9	Very high	33 Å²	33	51.2 Å²	51.2	15%	0.145	27%	0.265	C	S	.	.	S	Bend	trans	-85.5	-8.5	175.9	-79.7	-97.5	0	0	0	113.4	F74 D78 K86 A146 P149 H150	F74-F76 HydrophobicContact CB-CD2 4.48Å; F74-F76 HydrophobicContact CB-CE2 4.15Å; F74-F76 VanDerWaalsContact O-CD2 3.3Å; F74-F76 WeakPolarHBondContact O-CD2 3.47Å; F74-F76 PolarHBondContact O-N 3.19Å; F76-D78 VanDerWaalsContact C-N 3.32Å; F76-K86 HydrophobicContact CE1-CD 4.24Å; F76-K86 HydrophobicContact CZ-CD 4.35Å; F76-K86 HydrophobicContact CZ-CG 4.23Å; F76-A146 HydrophobicContact CB-CB 3.94Å; F76-A146 WeakPolarHBondContact CB-O 3.45Å; F76-A146 WeakPolarHBondContact CD1-O 3.33Å; F76-P149 HydrophobicContact CE1-CB 4.5Å; F76-P149 HydrophobicContact CE1-CG 4.36Å; F76-H150 HydrophobicContact CE2-CB 4.42Å; F76-H150 AromaticContact CE2-CE1 3.78Å; F76-H150 AromaticContact CE2-CG 3.87Å; F76-H150 AromaticContact CE2-ND1 3.47Å; F76-H150 WeakPolarHBondContact CE2-ND1 3.27Å; F76-H150 HydrophobicContact CZ-CB 4.42Å; F76-H150 AromaticContact CZ-CD2 3.75Å; F76-H150 AromaticContact CZ-CE1 3.53Å; F76-H150 AromaticContact CZ-CG 3.66Å; F76-H150 AromaticContact CZ-ND1 3.56Å; F76-H150 AromaticContact CZ-NE2 3.67Å
77	M	84.9	Confident	90.8	Very high	52 Å²	52	55.3 Å²	55.3	26%	0.256	28%	0.284	S	S	.	.	S	Bend	trans	-69	-34.5	174	-62.9	-55.8	-50.3	0	0	111.8	R29 S30 D75 T79 A146	R29-M77 HydrophobicContact CB-CE 4.41Å; S30-M77 WeakPolarHBondContact O-CE 3.37Å; S30-M77 WeakPolarHBondContact OG-CE 3.45Å; S30-M77 PolarHBondContact OG-SD 3.41Å; D75-M77 WeakPolarHBondContact OD1-CB 3.42Å; D75-M77 WeakPolarHBondContact OD1-CG 3.41Å; D75-M77 PolarHBondContact OD1-N 2.89Å; M77-T79 PolarHBondContact O-N 3.48Å; M77-A146 HydrophobicContact SD-CB 4.06Å
78	D	86.4	Confident	90.7	Very high	78 Å²	78	57.7 Å²	57.7	42%	0.417	29%	0.294	S	S	.	.	S	Bend	trans	-85.5	93.7	162.8	-173.4	-6.9	0	0	0	109.4	F76 L80 S81 K86	F76-D78 VanDerWaalsContact C-N 3.32Å; D78-L80 PolarHBondContact O-N 3.47Å; D78-L80 VanDerWaalsContact O-N 3.13Å; D78-L80 PolarHBondContact OD1-N 3.28Å; D78-S81 WeakPolarHBondContact CB-OG 3.35Å; D78-S81 PolarHBondContact O-N 3.07Å; D78-S81 PolarHBondContact O-OG 3.41Å; D78-S81 VanDerWaalsContact O-OG 3.08Å; D78-S81 PolarHBondContact OD1-N 3.31Å; D78-S81 WeakPolarHBondContact OD2-CB 3.11Å; D78-K86 PolarHBondContact O-NZ 3.45Å
79	T	82.7	Confident	90.7	Very high	102 Å²	102	53.6 Å²	53.6	63%	0.626	27%	0.274	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.4	-14.7	-178.4	54.7	0	0	0	0	114.2	M77 L83	M77-T79 PolarHBondContact O-N 3.48Å; T79-L83 VanDerWaalsContact O-CD2 3.31Å; T79-L83 WeakPolarHBondContact O-CD2 3.48Å
80	L	84.6	Confident	90.8	Very high	138 Å²	138	57.7 Å²	57.7	72%	0.723	29%	0.288	S	S	*	.	T	Hydrogen-bonded Turn	trans	-107.9	-15	-174.7	-60.8	178.7	0	0	0	113.3	D78	D78-L80 PolarHBondContact O-N 3.47Å; D78-L80 VanDerWaalsContact O-N 3.13Å; D78-L80 PolarHBondContact OD1-N 3.28Å
81	S	87.4	Confident	90.8	Very high	26 Å²	26	60.6 Å²	60.6	18%	0.182	31%	0.309	C	S	.	.	T	Hydrogen-bonded Turn	trans	-73.7	147.8	175.8	62.7	0	0	0	0	112.4	D78 L83 K86	D78-S81 WeakPolarHBondContact CB-OG 3.35Å; D78-S81 PolarHBondContact O-N 3.07Å; D78-S81 PolarHBondContact O-OG 3.41Å; D78-S81 VanDerWaalsContact O-OG 3.08Å; D78-S81 PolarHBondContact OD1-N 3.31Å; D78-S81 WeakPolarHBondContact OD2-CB 3.11Å; S81-L83 PolarHBondContact O-N 3.17Å; S81-K86 WeakPolarHBondContact O-CD 3.38Å; S81-K86 WeakPolarHBondContact O-CE 2.99Å; S81-K86 PolarHBondContact O-NZ 3.45Å; S81-K86 PolarHBondContact OG-NZ 2.83Å
82	D	86.3	Confident	90.8	Very high	52 Å²	52	60.1 Å²	60.1	28%	0.278	31%	0.305	S	S	.	.	T	Hydrogen-bonded Turn	trans	52.6	24.2	166.4	-55.4	-46.6	0	0	0	115.2	F74 K84 M85 K86	F74-D82 HydrophobicContact CD1-CB 3.83Å; F74-D82 HydrophobicContact CE1-CB 4.06Å; D82-K84 PolarHBondContact O-N 2.71Å; D82-K84 VanDerWaalsContact O-N 3.12Å; D82-M85 HydrophobicContact CB-CB 4.35Å; D82-M85 CarbonylContact O-C 3.56Å; D82-M85 WeakPolarHBondContact O-CA 3.06Å; D82-M85 PolarHBondContact O-N 3.35Å; D82-K86 HydrophobicContact CB-CG 4.49Å; D82-K86 PolarHBondContact O-N 3.11Å
83	L	90.4	Very high	91.1	Very high	102 Å²	102	57.8 Å²	57.8	53%	0.534	29%	0.292	S	S	.	.	H	α-helix	trans	-50.6	-44.7	-173.8	-72.9	176.3	0	0	0	112.7	T79 S81 M85 E87	T79-L83 VanDerWaalsContact O-CD2 3.31Å; T79-L83 WeakPolarHBondContact O-CD2 3.48Å; S81-L83 PolarHBondContact O-N 3.17Å; L83-M85 VanDerWaalsContact C-N 3.32Å; L83-M85 PolarHBondContact O-N 3.25Å; L83-E87 VanDerWaalsContact O-CB 3.3Å; L83-E87 WeakPolarHBondContact O-CB 3.14Å; L83-E87 PolarHBondContact O-N 3.12Å
84	K	91.7	Very high	91.3	Very high	167 Å²	167	59 Å²	59	73%	0.726	30%	0.299	S	S	*	.	H	α-helix	trans	-61.6	-39.9	177.1	-174	-179.8	178.5	-175.8	0	112.3	D82 Y88	D82-K84 PolarHBondContact O-N 2.71Å; D82-K84 VanDerWaalsContact O-N 3.12Å; K84-Y88 VanDerWaalsContact O-CB 3.29Å; K84-Y88 WeakPolarHBondContact O-CB 3.25Å; K84-Y88 PolarHBondContact O-N 3.25Å
85	M	92.1	Very high	91.6	Very high	33 Å²	33	60.1 Å²	60.1	16%	0.163	30%	0.304	C	S	.	.	H	α-helix	trans	-80.6	-35.8	-177.1	-63.3	-64.7	162.2	0	0	111.9	I43 L45 F74 D82 L83 E87 Y88 K89	I43-M85 WeakPolarHBondContact O-CG 3.29Å; L45-M85 HydrophobicContact CB-SD 4.03Å; F74-M85 HydrophobicContact CE1-CB 3.49Å; F74-M85 VanDerWaalsContact CE1-CB 3.49Å; F74-M85 HydrophobicContact CZ-CB 3.62Å; D82-M85 HydrophobicContact CB-CB 4.35Å; D82-M85 CarbonylContact O-C 3.56Å; D82-M85 WeakPolarHBondContact O-CA 3.06Å; D82-M85 PolarHBondContact O-N 3.35Å; L83-M85 VanDerWaalsContact C-N 3.32Å; L83-M85 PolarHBondContact O-N 3.25Å; M85-E87 VanDerWaalsContact C-N 3.34Å; M85-Y88 PolarHBondContact O-N 3.3Å; M85-K89 WeakPolarHBondContact O-CB 3.47Å; M85-K89 PolarHBondContact O-N 3.12Å
86	K	93.4	Very high	92.1	Very high	12 Å²	12	58 Å²	58	5%	0.052	29%	0.293	C	S	.	.	H	α-helix	trans	-58	-47.2	167.7	-73.9	171.1	176.4	160	0	110.6	F74 D75 F76 D78 S81 D82 K89 R90 H150	F74-K86 HydrophobicContact CB-CD 4.43Å; F74-K86 HydrophobicContact CB-CG 3.75Å; F74-K86 HydrophobicContact CD1-CG 4Å; F74-K86 HydrophobicContact CD2-CG 4.38Å; F74-K86 HydrophobicContact CG-CG 3.78Å; D75-K86 WeakPolarHBondContact O-CE 3.41Å; D75-K86 PolarHBondContact O-NZ 3.44Å; F76-K86 HydrophobicContact CE1-CD 4.24Å; F76-K86 HydrophobicContact CZ-CD 4.35Å; F76-K86 HydrophobicContact CZ-CG 4.23Å; D78-K86 PolarHBondContact O-NZ 3.45Å; S81-K86 WeakPolarHBondContact O-CD 3.38Å; S81-K86 WeakPolarHBondContact O-CE 2.99Å; S81-K86 PolarHBondContact O-NZ 3.45Å; S81-K86 PolarHBondContact OG-NZ 2.83Å; D82-K86 HydrophobicContact CB-CG 4.49Å; D82-K86 PolarHBondContact O-N 3.11Å; K86-K89 PolarHBondContact O-N 2.91Å; K86-R90 WeakPolarHBondContact O-CB 3.22Å; K86-R90 PolarHBondContact O-N 3.4Å; K86-H150 PolarHBondContact O-CE1 3.19Å; K86-H150 PolarHBondContact O-NE2 3.43Å
87	E	94.1	Very high	92.4	Very high	87 Å²	87	56.6 Å²	56.6	41%	0.407	29%	0.287	S	S	.	.	H	α-helix	trans	-66.9	-41.5	177.8	-176.8	54	-153.1	0	0	112.1	L83 M85 K89 R90 S91	L83-E87 VanDerWaalsContact O-CB 3.3Å; L83-E87 WeakPolarHBondContact O-CB 3.14Å; L83-E87 PolarHBondContact O-N 3.12Å; M85-E87 VanDerWaalsContact C-N 3.34Å; E87-K89 PolarHBondContact O-N 2.85Å; E87-R90 VanDerWaalsContact CD-NH2 3.35Å; E87-R90 WeakPolarHBondContact O-CB 3.42Å; E87-R90 PolarHBondContact O-N 2.78Å; E87-R90 IonicContact OE1-CZ 2.89Å; E87-R90 IonicContact OE1-NE 2.86Å; E87-R90 PolarHBondContact OE1-NE 3.2Å; E87-R90 IonicContact OE1-NH2 2.67Å; E87-R90 PolarHBondContact OE1-NH2 3.16Å; E87-R90 IonicContact OE2-CZ 3.59Å; E87-R90 IonicContact OE2-NE 2.85Å; E87-R90 PolarHBondContact OE2-NE 3.08Å; E87-R90 IonicContact OE2-NH2 3.27Å; E87-R90 PolarHBondContact OE2-NH2 3.47Å; E87-S91 PolarHBondContact O-N 3.36Å
88	Y	94.3	Very high	92.9	Very high	51 Å²	51	58 Å²	58	20%	0.2	30%	0.295	C	S	.	.	H	α-helix	trans	-60.3	-44.9	175.3	177.2	-98.5	0	0	0	112.2	L45 T46 P47 L48 Q69 K84 M85 S91 T92	L45-Y88 HydrophobicContact CB-CD1 3.83Å; L45-Y88 HydrophobicContact CB-CE1 3.87Å; L45-Y88 HydrophobicContact CD1-CD1 3.73Å; L45-Y88 HydrophobicContact CD1-CE1 4.21Å; L45-Y88 HydrophobicContact CG-CD1 4.45Å; T46-Y88 PolarHBondContact O-OH 2.76Å; P47-Y88 WeakPolarHBondContact CA-OH 3.3Å; P47-Y88 HydrophobicContact CB-CE2 4.42Å; L48-Y88 PolarHBondContact N-OH 2.73Å; Q69-Y88 PolarHBondContact OE1-OH 3.46Å; K84-Y88 VanDerWaalsContact O-CB 3.29Å; K84-Y88 WeakPolarHBondContact O-CB 3.25Å; K84-Y88 PolarHBondContact O-N 3.25Å; M85-Y88 PolarHBondContact O-N 3.3Å; Y88-S91 PolarHBondContact O-N 3.29Å; Y88-T92 WeakPolarHBondContact O-CB 3.47Å; Y88-T92 PolarHBondContact O-N 3.29Å; Y88-T92 PolarHBondContact O-OG1 2.87Å
89	K	96.1	Very high	93.3	Very high	2 Å²	2	55.3 Å²	55.3	1%	0.009	28%	0.279	C	S	.	.	H	α-helix	trans	-62.4	-42.1	173.4	177.4	172.1	169.8	-171.4	0	111.5	L45 C70 V72 F74 M85 K86 E87 T92 L93 N122	L45-K89 HydrophobicContact CD1-CB 4.12Å; C70-K89 WeakPolarHBondContact O-CE 3.45Å; C70-K89 PolarHBondContact O-NZ 2.75Å; V72-K89 WeakPolarHBondContact O-CD 3.45Å; V72-K89 PolarHBondContact O-NZ 2.72Å; F74-K89 HydrophobicContact CD2-CD 3.84Å; F74-K89 HydrophobicContact CE2-CB 3.89Å; F74-K89 HydrophobicContact CE2-CD 3.66Å; F74-K89 HydrophobicContact CE2-CG 4.4Å; M85-K89 WeakPolarHBondContact O-CB 3.47Å; M85-K89 PolarHBondContact O-N 3.12Å; K86-K89 PolarHBondContact O-N 2.91Å; E87-K89 PolarHBondContact O-N 2.85Å; K89-T92 PolarHBondContact O-N 2.95Å; K89-L93 HydrophobicContact CG-CD1 4.01Å; K89-L93 HydrophobicContact CG-CG 4.31Å; K89-L93 WeakPolarHBondContact O-CG 3.42Å; K89-L93 PolarHBondContact O-N 3.09Å; K89-N122 PolarHBondContact NZ-OD1 3.19Å
90	R	96.3	Very high	93.9	Very high	115 Å²	115	50.8 Å²	50.8	43%	0.434	25%	0.251	S	S	.	.	H	α-helix	trans	-57.9	-50	176.7	-171.1	-177.3	75.6	118.1	0.7	111.3	K86 E87 T92 L93 N94 L153	K86-R90 WeakPolarHBondContact O-CB 3.22Å; K86-R90 PolarHBondContact O-N 3.4Å; E87-R90 VanDerWaalsContact CD-NH2 3.35Å; E87-R90 WeakPolarHBondContact O-CB 3.42Å; E87-R90 PolarHBondContact O-N 2.78Å; E87-R90 IonicContact OE1-CZ 2.89Å; E87-R90 IonicContact OE1-NE 2.86Å; E87-R90 PolarHBondContact OE1-NE 3.2Å; E87-R90 IonicContact OE1-NH2 2.67Å; E87-R90 PolarHBondContact OE1-NH2 3.16Å; E87-R90 IonicContact OE2-CZ 3.59Å; E87-R90 IonicContact OE2-NE 2.85Å; E87-R90 PolarHBondContact OE2-NE 3.08Å; E87-R90 IonicContact OE2-NH2 3.27Å; E87-R90 PolarHBondContact OE2-NH2 3.47Å; R90-T92 VanDerWaalsContact C-N 3.31Å; R90-T92 PolarHBondContact O-N 3.45Å; R90-L93 PolarHBondContact O-N 3.16Å; R90-N94 PolarHBondContact O-N 3.2Å; R90-L153 HydrophobicContact CG-CD1 3.75Å; R90-L153 WeakPolarHBondContact O-CD1 3.48Å
91	S	96.6	Very high	94.3	Very high	64 Å²	64	47.4 Å²	47.4	45%	0.448	24%	0.236	S	C	.	.	H	α-helix	trans	-61.7	-38.9	176.9	-174.3	0	0	0	0	112.2	E87 Y88 N94 E95	E87-S91 PolarHBondContact O-N 3.36Å; Y88-S91 PolarHBondContact O-N 3.29Å; S91-N94 PolarHBondContact O-N 2.94Å; S91-E95 WeakPolarHBondContact O-CB 3.34Å; S91-E95 PolarHBondContact O-N 3.24Å
92	T	97	Very high	94.5	Very high	5 Å²	5	52.5 Å²	52.5	3%	0.031	26%	0.26	C	S	.	.	H	α-helix	trans	-66.1	-44.8	177.3	-56	0	0	0	0	111.1	K66 Y88 K89 R90 N94 E95 L96	K66-T92 HydrophobicContact CB-CG2 3.91Å; K66-T92 HydrophobicContact CD-CG2 4.24Å; K66-T92 HydrophobicContact CG-CG2 3.99Å; Y88-T92 WeakPolarHBondContact O-CB 3.47Å; Y88-T92 PolarHBondContact O-N 3.29Å; Y88-T92 PolarHBondContact O-OG1 2.87Å; K89-T92 PolarHBondContact O-N 2.95Å; R90-T92 VanDerWaalsContact C-N 3.31Å; R90-T92 PolarHBondContact O-N 3.45Å; T92-N94 VanDerWaalsContact C-N 3.35Å; T92-N94 PolarHBondContact O-N 3.32Å; T92-E95 WeakPolarHBondContact O-CB 3.42Å; T92-E95 PolarHBondContact O-N 3.02Å; T92-L96 HydrophobicContact CG2-CD1 4.46Å; T92-L96 VanDerWaalsContact O-CG 3.28Å; T92-L96 WeakPolarHBondContact O-CG 3.43Å; T92-L96 PolarHBondContact O-N 3.46Å
93	L	97.9	Very high	94.6	Very high	0 Å²	0	51.5 Å²	51.5	0%	0	26%	0.257	C	S	.	.	H	α-helix	trans	-60.9	-42.4	176.2	-75.8	169.7	0	0	0	111.9	C70 K89 R90 E95 L96 V97 M118 H150 L153 V154	C70-L93 HydrophobicContact CB-CD2 3.9Å; C70-L93 HydrophobicContact CB-CG 4.49Å; K89-L93 HydrophobicContact CG-CD1 4.01Å; K89-L93 HydrophobicContact CG-CG 4.31Å; K89-L93 WeakPolarHBondContact O-CG 3.42Å; K89-L93 PolarHBondContact O-N 3.09Å; R90-L93 PolarHBondContact O-N 3.16Å; L93-E95 VanDerWaalsContact C-N 3.34Å; L93-E95 PolarHBondContact O-N 2.95Å; L93-L96 HydrophobicContact CD2-CD1 4.44Å; L93-L96 WeakPolarHBondContact O-CB 3.4Å; L93-L96 PolarHBondContact O-N 2.77Å; L93-V97 WeakPolarHBondContact O-CG2 3.37Å; L93-V97 PolarHBondContact O-N 2.87Å; L93-M118 HydrophobicContact CD2-CE 4.45Å; L93-M118 HydrophobicContact CD2-SD 4.22Å; L93-H150 HydrophobicContact CD1-CB 4.21Å; L93-L153 HydrophobicContact CB-CB 3.77Å; L93-L153 HydrophobicContact CB-CD1 3.79Å; L93-L153 HydrophobicContact CB-CG 4.43Å; L93-L153 HydrophobicContact CD1-CB 4.24Å; L93-V154 HydrophobicContact CD1-CG2 4.04Å; L93-V154 HydrophobicContact CD2-CG2 3.9Å
94	N	97.2	Very high	94.4	Very high	75 Å²	75	57.5 Å²	57.5	40%	0.401	27%	0.273	S	S	.	.	H	α-helix	trans	-60.9	-44.8	175.7	-165.7	89	0	0	0	111.5	R90 S91 T92 L96 V97 D98 L153	R90-N94 PolarHBondContact O-N 3.2Å; S91-N94 PolarHBondContact O-N 2.94Å; T92-N94 VanDerWaalsContact C-N 3.35Å; T92-N94 PolarHBondContact O-N 3.32Å; N94-L96 VanDerWaalsContact C-N 3.29Å; N94-L96 PolarHBondContact O-N 3.07Å; N94-V97 WeakPolarHBondContact O-CB 3.33Å; N94-V97 PolarHBondContact O-N 3.37Å; N94-D98 PolarHBondContact ND2-OD2 3.47Å; N94-D98 PolarHBondContact O-N 3.41Å; N94-L153 HydrophobicContact CB-CD1 4.5Å
95	E	97.2	Very high	94	Very high	25 Å²	25	51.9 Å²	51.9	12%	0.117	26%	0.262	C	S	.	.	H	α-helix	trans	-60.1	-38.5	175.3	-173.5	-173.2	-156.2	0	0	112.3	L50 L51 K66 S91 T92 L93 D98 Y99	L50-E95 WeakPolarHBondContact CA-OE1 3.4Å; L50-E95 WeakPolarHBondContact CB-OE1 3.46Å; L51-E95 HydrophobicContact CD1-CG 4.17Å; L51-E95 PolarHBondContact N-OE1 3.03Å; K66-E95 VanDerWaalsContact CE-OE2 3.3Å; K66-E95 WeakPolarHBondContact CE-OE2 3.49Å; K66-E95 IonicContact NZ-OE1 3.35Å; K66-E95 IonicContact NZ-OE2 2.76Å; K66-E95 PolarHBondContact NZ-OE2 3.46Å; S91-E95 WeakPolarHBondContact O-CB 3.34Å; S91-E95 PolarHBondContact O-N 3.24Å; T92-E95 WeakPolarHBondContact O-CB 3.42Å; T92-E95 PolarHBondContact O-N 3.02Å; L93-E95 VanDerWaalsContact C-N 3.34Å; L93-E95 PolarHBondContact O-N 2.95Å; E95-D98 PolarHBondContact O-N 3.3Å; E95-Y99 VanDerWaalsContact O-CB 3.27Å; E95-Y99 WeakPolarHBondContact O-CB 3.18Å; E95-Y99 PolarHBondContact O-N 2.95Å
96	L	97.3	Very high	93.8	Very high	0 Å²	0	50.4 Å²	50.4	0%	0	26%	0.255	C	S	.	.	H	α-helix	trans	-65.2	-38.7	175.7	-66.3	172.6	0	0	0	112	L51 F63 K66 L67 T92 L93 N94 I100 F157	L51-L96 HydrophobicContact CD1-CD2 4.48Å; F63-L96 HydrophobicContact CD2-CD2 3.29Å; F63-L96 HydrophobicContact CE2-CB 4.33Å; F63-L96 HydrophobicContact CE2-CD2 3.28Å; F63-L96 HydrophobicContact CE2-CG 4.38Å; F63-L96 HydrophobicContact CG-CD2 4.48Å; F63-L96 HydrophobicContact CZ-CD2 4.47Å; K66-L96 HydrophobicContact CB-CD2 3.83Å; K66-L96 HydrophobicContact CB-CG 4.49Å; K66-L96 HydrophobicContact CD-CD2 4.47Å; L67-L96 HydrophobicContact CD2-CD1 4.03Å; T92-L96 HydrophobicContact CG2-CD1 4.46Å; T92-L96 VanDerWaalsContact O-CG 3.28Å; T92-L96 WeakPolarHBondContact O-CG 3.43Å; T92-L96 PolarHBondContact O-N 3.46Å; L93-L96 HydrophobicContact CD2-CD1 4.44Å; L93-L96 WeakPolarHBondContact O-CB 3.4Å; L93-L96 PolarHBondContact O-N 2.77Å; N94-L96 VanDerWaalsContact C-N 3.29Å; N94-L96 PolarHBondContact O-N 3.07Å; L96-I100 WeakPolarHBondContact O-CG2 3.25Å; L96-I100 PolarHBondContact O-N 2.87Å; L96-F157 HydrophobicContact CB-CD2 3.89Å; L96-F157 HydrophobicContact CB-CE2 3.89Å
97	V	97.1	Very high	93.8	Very high	3 Å²	3	50.5 Å²	50.5	2%	0.018	26%	0.256	C	S	.	.	H	α-helix	trans	-62.9	-45.9	174.4	173.3	0	0	0	0	110.9	L93 N94 I100 T101 E156 F157 R160	L93-V97 WeakPolarHBondContact O-CG2 3.37Å; L93-V97 PolarHBondContact O-N 2.87Å; N94-V97 WeakPolarHBondContact O-CB 3.33Å; N94-V97 PolarHBondContact O-N 3.37Å; V97-I100 WeakPolarHBondContact O-CG2 3.37Å; V97-T101 WeakPolarHBondContact O-CB 3.08Å; V97-T101 PolarHBondContact O-N 2.99Å; V97-T101 PolarHBondContact O-OG1 3.44Å; V97-E156 HydrophobicContact CG1-CG 3.92Å; V97-E156 HydrophobicContact CG2-CG 4.38Å; V97-F157 HydrophobicContact CG2-CB 3.75Å; V97-F157 HydrophobicContact CG2-CD2 4.47Å; V97-R160 HydrophobicContact CG1-CG 4.46Å
98	D	95.5	Very high	93.7	Very high	81 Å²	81	49 Å²	49	43%	0.433	25%	0.253	S	S	.	.	H	α-helix	trans	-63.8	-46.1	178	-68.1	-29.7	0	0	0	110.8	N94 E95 T101 I102	N94-D98 PolarHBondContact ND2-OD2 3.47Å; N94-D98 PolarHBondContact O-N 3.41Å; E95-D98 PolarHBondContact O-N 3.3Å; D98-T101 PolarHBondContact O-N 3.19Å; D98-I102 WeakPolarHBondContact O-CG1 2.93Å; D98-I102 PolarHBondContact O-N 2.99Å; D98-I102 VanDerWaalsContact O-N 3.12Å
99	Y	95	Very high	93.6	Very high	22 Å²	22	52.6 Å²	52.6	9%	0.086	27%	0.271	C	S	.	.	H	α-helix	trans	-61.9	-48.4	-178	-175.7	-106.5	0	0	0	112.5	L51 Q59 F63 E95 T101 I102 S103 C106	L51-Y99 HydrophobicContact CB-CD2 4.1Å; L51-Y99 HydrophobicContact CB-CE2 4.45Å; L51-Y99 HydrophobicContact CD1-CD1 4.07Å; L51-Y99 HydrophobicContact CD1-CD2 3.93Å; L51-Y99 HydrophobicContact CD1-CG 3.66Å; L51-Y99 HydrophobicContact CD2-CD2 4.44Å; L51-Y99 HydrophobicContact CD2-CE2 4.3Å; L51-Y99 HydrophobicContact CG-CD2 4.38Å; Q59-Y99 HydrophobicContact CB-CE2 4.2Å; Q59-Y99 WeakPolarHBondContact CB-OH 3.47Å; Q59-Y99 PolarHBondContact OE1-OH 3.07Å; F63-Y99 HydrophobicContact CB-CD1 4.49Å; F63-Y99 HydrophobicContact CB-CE1 4.06Å; F63-Y99 HydrophobicContact CD1-CE1 4.26Å; F63-Y99 AromaticContact CD2-CD1 3.44Å; F63-Y99 HydrophobicContact CD2-CD1 3.44Å; F63-Y99 VanDerWaalsContact CD2-CD1 3.44Å; F63-Y99 AromaticContact CD2-CE1 3.81Å; F63-Y99 HydrophobicContact CD2-CE1 3.81Å; F63-Y99 HydrophobicContact CD2-CG 4.42Å; F63-Y99 AromaticContact CE2-CD1 3.63Å; F63-Y99 HydrophobicContact CE2-CD1 3.63Å; F63-Y99 HydrophobicContact CE2-CE1 4.29Å; F63-Y99 AromaticContact CG-CD1 3.94Å; F63-Y99 HydrophobicContact CG-CD1 3.94Å; F63-Y99 AromaticContact CG-CE1 3.8Å; F63-Y99 HydrophobicContact CG-CE1 3.8Å; F63-Y99 HydrophobicContact CZ-CD1 4.26Å; E95-Y99 VanDerWaalsContact O-CB 3.27Å; E95-Y99 WeakPolarHBondContact O-CB 3.18Å; E95-Y99 PolarHBondContact O-N 2.95Å; Y99-T101 PolarHBondContact O-N 3.49Å; Y99-I102 PolarHBondContact O-N 3.21Å; Y99-S103 WeakPolarHBondContact CD2-OG 3.15Å; Y99-S103 WeakPolarHBondContact CE2-OG 3.41Å; Y99-S103 WeakPolarHBondContact O-CB 3.14Å; Y99-S103 PolarHBondContact O-N 3.49Å; Y99-S103 PolarHBondContact O-OG 2.88Å; Y99-S103 VanDerWaalsContact O-OG 3.12Å; Y99-C106 HydrophobicContact CD1-CB 4.38Å; Y99-C106 HydrophobicContact CE1-CB 3.64Å
100	I	94.7	Very high	93.5	Very high	7 Å²	7	59 Å²	59	4%	0.036	30%	0.302	C	S	.	.	H	α-helix	trans	-67.8	-24.3	-179.7	-163	166.5	0	0	0	112.8	L96 V97 L107 F157 R160 F161	L96-I100 WeakPolarHBondContact O-CG2 3.25Å; L96-I100 PolarHBondContact O-N 2.87Å; V97-I100 WeakPolarHBondContact O-CG2 3.37Å; I100-L107 HydrophobicContact CD1-CD2 4.02Å; I100-L107 HydrophobicContact CG1-CD2 4.31Å; I100-F157 HydrophobicContact CB-CD2 4.49Å; I100-F157 HydrophobicContact CB-CE2 3.99Å; I100-F157 HydrophobicContact CD1-CD2 4.45Å; I100-F157 HydrophobicContact CD1-CE2 3.73Å; I100-F157 HydrophobicContact CD1-CZ 3.85Å; I100-F157 HydrophobicContact CG1-CE2 4.49Å; I100-F157 HydrophobicContact CG2-CD2 3.87Å; I100-F157 HydrophobicContact CG2-CE2 3.88Å; I100-R160 HydrophobicContact CG2-CB 3.83Å; I100-F161 HydrophobicContact CD1-CB 3.57Å; I100-F161 HydrophobicContact CD1-CD2 3.97Å; I100-F161 HydrophobicContact CD1-CG 4.27Å
101	T	93.6	Very high	93.4	Very high	67 Å²	67	53.6 Å²	53.6	41%	0.411	28%	0.281	S	S	.	.	H	α-helix	trans	-77.5	-38.9	179.4	-60.1	0	0	0	0	111.7	V97 D98 Y99 R160	V97-T101 WeakPolarHBondContact O-CB 3.08Å; V97-T101 PolarHBondContact O-N 2.99Å; V97-T101 PolarHBondContact O-OG1 3.44Å; D98-T101 PolarHBondContact O-N 3.19Å; Y99-T101 PolarHBondContact O-N 3.49Å; T101-R160 VanDerWaalsContact CG2-NH1 3.32Å; T101-R160 PolarHBondContact OG1-NH1 3.04Å
102	I	91.2	Very high	93.4	Very high	132 Å²	132	50.6 Å²	50.6	68%	0.677	26%	0.26	S	S	*	.	H	α-helix	trans	-100.4	-35.6	-170	-58.2	168.2	0	0	0	111.9	D98 Y99	D98-I102 WeakPolarHBondContact O-CG1 2.93Å; D98-I102 PolarHBondContact O-N 2.99Å; D98-I102 VanDerWaalsContact O-N 3.12Å; Y99-I102 PolarHBondContact O-N 3.21Å
103	S	87.9	Confident	93.5	Very high	31 Å²	31	52.2 Å²	52.2	22%	0.217	27%	0.271	C	S	.	.			trans	-81.1	130.6	-171.3	-60.5	0	0	0	0	112.5	Y99 C106	Y99-S103 WeakPolarHBondContact CD2-OG 3.15Å; Y99-S103 WeakPolarHBondContact CE2-OG 3.41Å; Y99-S103 WeakPolarHBondContact O-CB 3.14Å; Y99-S103 PolarHBondContact O-N 3.49Å; Y99-S103 PolarHBondContact O-OG 2.88Å; Y99-S103 VanDerWaalsContact O-OG 3.12Å; S103-C106 PolarHBondContact O-SG 2.85Å
104	R	85.6	Confident	93.4	Very high	229 Å²	229	54 Å²	54	86%	0.864	28%	0.279	S	S	*	.	S	Bend	trans	-90	146.6	170	-62.9	-172.5	-179	-168.2	-0.4	110.9	C106 E166	R104-C106 VanDerWaalsContact C-N 3.3Å; R104-C106 PolarHBondContact O-N 3.17Å; R104-E166 WeakPolarHBondContact CA-OE1 3.23Å
105	G	84.6	Confident	93.4	Very high	49 Å²	49	50.4 Å²	50.4	51%	0.505	26%	0.26	S	S	.	.	S	Bend	trans	76.6	9.4	179.3	0	0	0	0	0	114.8	L107 E166	G105-L107 VanDerWaalsContact C-N 3.33Å; G105-E166 WeakPolarHBondContact CA-OE2 3.4Å; G105-E166 PolarHBondContact N-OE1 3.32Å; G105-E166 PolarHBondContact N-OE2 3.38Å
106	C	87.8	Confident	93.5	Very high	2 Å²	2	49.8 Å²	49.8	1%	0.014	26%	0.258	C	S	.	.			trans	-75.9	-21	-177.5	63.6	0	0	0	0	113.2	Y99 S103 R104 T108 T111	Y99-C106 HydrophobicContact CD1-CB 4.38Å; Y99-C106 HydrophobicContact CE1-CB 3.64Å; S103-C106 PolarHBondContact O-SG 2.85Å; R104-C106 VanDerWaalsContact C-N 3.3Å; R104-C106 PolarHBondContact O-N 3.17Å; C106-T108 PolarHBondContact O-N 3.4Å; C106-T111 PolarHBondContact O-OG1 2.66Å
107	L	92.3	Very high	93.5	Very high	13 Å²	13	54.1 Å²	54.1	7%	0.068	27%	0.274	C	S	.	.			trans	-91.1	73.8	-177.1	-59.5	-169.5	0	0	0	112.5	I100 G105 T111 Y112 F161 E166 F167	I100-L107 HydrophobicContact CD1-CD2 4.02Å; I100-L107 HydrophobicContact CG1-CD2 4.31Å; G105-L107 VanDerWaalsContact C-N 3.33Å; L107-T111 HydrophobicContact CD2-CG2 3.96Å; L107-Y112 HydrophobicContact CB-CE2 4.46Å; L107-F161 HydrophobicContact CD1-CD2 4.12Å; L107-F161 HydrophobicContact CD1-CE2 4.29Å; L107-F161 HydrophobicContact CD2-CD2 3.79Å; L107-F161 HydrophobicContact CD2-CE2 3.97Å; L107-E166 HydrophobicContact CB-CB 4.4Å; L107-E166 HydrophobicContact CD1-CB 4.24Å; L107-F167 HydrophobicContact CD1-CB 4.49Å
108	T	91.8	Very high	93.5	Very high	56 Å²	56	54 Å²	54	34%	0.344	27%	0.273	S	S	.	.			trans	-79.6	165.5	171.8	74.1	0	0	0	0	111.9	C106 Q110 T111 Y112	C106-T108 PolarHBondContact O-N 3.4Å; T108-Q110 PolarHBondContact O-N 3.05Å; T108-Q110 VanDerWaalsContact O-N 3.15Å; T108-Q110 PolarHBondContact OG1-N 3.33Å; T108-T111 PolarHBondContact N-OG1 3.27Å; T108-T111 VanDerWaalsContact O-CB 3.25Å; T108-T111 WeakPolarHBondContact O-CB 3.19Å; T108-T111 PolarHBondContact O-N 3.46Å; T108-T111 PolarHBondContact O-OG1 2.89Å; T108-T111 PolarHBondContact OG1-N 2.74Å; T108-T111 PolarHBondContact OG1-OG1 2.88Å; T108-Y112 WeakPolarHBondContact O-CD2 3.19Å; T108-Y112 WeakPolarHBondContact O-CE2 3.3Å
109	E	92.5	Very high	93.6	Very high	126 Å²	126	50.2 Å²	50.2	59%	0.589	25%	0.253	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.3	-31.3	176.6	-66.1	-158.5	154.7	0	0	113.5	T111 P113 I171	E109-T111 VanDerWaalsContact C-N 3.33Å; E109-P113 VanDerWaalsContact O-CD 3.28Å; E109-P113 WeakPolarHBondContact O-CD 3.3Å; E109-I171 HydrophobicContact CG-CD1 3.89Å
110	Q	93.8	Very high	93.7	Very high	137 Å²	137	50.5 Å²	50.5	64%	0.64	26%	0.259	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74.8	-23.5	177.8	-62.8	-179.5	6.8	0	0	112.6	L64 T108 P113	L64-Q110 HydrophobicContact CD1-CB 4.34Å; T108-Q110 PolarHBondContact O-N 3.05Å; T108-Q110 VanDerWaalsContact O-N 3.15Å; T108-Q110 PolarHBondContact OG1-N 3.33Å; Q110-P113 WeakPolarHBondContact O-CD 3.36Å; Q110-P113 WeakPolarHBondContact O-CG 3.32Å
111	T	95.5	Very high	93.8	Very high	2 Å²	2	52.5 Å²	52.5	1%	0.012	27%	0.272	C	S	.	.	H	α-helix	trans	-68.2	-40.3	179.7	-53.2	0	0	0	0	111.8	F63 C106 L107 T108 E109 E114 V115	F63-T111 HydrophobicContact CD1-CG2 4.16Å; F63-T111 HydrophobicContact CE1-CG2 3.58Å; C106-T111 PolarHBondContact O-OG1 2.66Å; L107-T111 HydrophobicContact CD2-CG2 3.96Å; T108-T111 PolarHBondContact N-OG1 3.27Å; T108-T111 VanDerWaalsContact O-CB 3.25Å; T108-T111 WeakPolarHBondContact O-CB 3.19Å; T108-T111 PolarHBondContact O-N 3.46Å; T108-T111 PolarHBondContact O-OG1 2.89Å; T108-T111 PolarHBondContact OG1-N 2.74Å; T108-T111 PolarHBondContact OG1-OG1 2.88Å; E109-T111 VanDerWaalsContact C-N 3.33Å; T111-E114 PolarHBondContact O-N 2.78Å; T111-V115 HydrophobicContact CG2-CG2 3.88Å; T111-V115 WeakPolarHBondContact O-CG2 3.15Å; T111-V115 PolarHBondContact O-N 3.35Å
112	Y	97.1	Very high	94	Very high	0 Å²	0	49.8 Å²	49.8	0%	0	26%	0.255	C	S	.	.	H	α-helix	trans	-55.3	-53.4	-176.5	-71	-98.2	0	0	0	114.6	L107 T108 E114 V115 V116 F161 E166 F167 Q168 I171 A172	L107-Y112 HydrophobicContact CB-CE2 4.46Å; T108-Y112 WeakPolarHBondContact O-CD2 3.19Å; T108-Y112 WeakPolarHBondContact O-CE2 3.3Å; Y112-E114 VanDerWaalsContact C-N 3.31Å; Y112-E114 PolarHBondContact O-N 3.06Å; Y112-V115 PolarHBondContact O-N 3.34Å; Y112-V116 WeakPolarHBondContact O-CG2 3.29Å; Y112-V116 PolarHBondContact O-N 3.26Å; Y112-F161 HydrophobicContact CD1-CE2 4.09Å; Y112-F161 AromaticContact CD1-CZ 3.56Å; Y112-F161 HydrophobicContact CD1-CZ 3.56Å; Y112-F161 HydrophobicContact CE1-CE2 4.06Å; Y112-F161 AromaticContact CE1-CZ 3.8Å; Y112-F161 HydrophobicContact CE1-CZ 3.8Å; Y112-F161 HydrophobicContact CG-CZ 4.3Å; Y112-E166 PolarHBondContact OH-O 3.19Å; Y112-F167 HydrophobicContact CD1-CE2 4.48Å; Y112-F167 AromaticContact CE1-CD2 3.94Å; Y112-F167 HydrophobicContact CE1-CD2 3.94Å; Y112-F167 AromaticContact CE1-CE2 3.88Å; Y112-F167 HydrophobicContact CE1-CE2 3.88Å; Y112-Q168 PolarHBondContact OH-N 3.09Å; Y112-I171 HydrophobicContact CD1-CG2 4.23Å; Y112-I171 HydrophobicContact CD2-CB 4.4Å; Y112-I171 HydrophobicContact CD2-CG2 3.65Å; Y112-I171 HydrophobicContact CE2-CB 4.38Å; Y112-I171 HydrophobicContact CE2-CD1 4.28Å; Y112-I171 HydrophobicContact CE2-CG2 4.08Å; Y112-I171 HydrophobicContact CG-CG2 3.77Å; Y112-A172 HydrophobicContact CD1-CB 3.65Å; Y112-A172 HydrophobicContact CE1-CB 3.81Å
113	P	97.1	Very high	94.2	Very high	40 Å²	40	43.5 Å²	43.5	26%	0.26	22%	0.223	S	C	.	.	H	α-helix	trans	-62.2	-38	179.6	22.1	-32.3	0	0	0	112.4	E109 Q110 V116 R117 Y175	E109-P113 VanDerWaalsContact O-CD 3.28Å; E109-P113 WeakPolarHBondContact O-CD 3.3Å; Q110-P113 WeakPolarHBondContact O-CD 3.36Å; Q110-P113 WeakPolarHBondContact O-CG 3.32Å; P113-V116 PolarHBondContact O-N 3.4Å; P113-R117 WeakPolarHBondContact O-CB 3.33Å; P113-R117 PolarHBondContact O-N 2.87Å; P113-Y175 HydrophobicContact CB-CD1 4.08Å; P113-Y175 HydrophobicContact CB-CE1 3.69Å; P113-Y175 HydrophobicContact CB-CE2 4.4Å; P113-Y175 HydrophobicContact CG-CE1 4.31Å; P113-Y175 HydrophobicContact CG-CE2 4.46Å
114	E	97.2	Very high	94.6	Very high	37 Å²	37	43.1 Å²	43.1	17%	0.173	22%	0.218	C	C	.	.	H	α-helix	trans	-69.7	-39.6	179.9	-68.6	-61.8	169	0	0	112.5	L64 L67 Q68 T111 Y112 R117 M118	L64-E114 HydrophobicContact CD2-CB 4.17Å; L64-E114 HydrophobicContact CD2-CG 4.05Å; L67-E114 HydrophobicContact CB-CB 4.37Å; L67-E114 HydrophobicContact CD1-CB 4.08Å; Q68-E114 WeakPolarHBondContact CG-OE2 3.44Å; Q68-E114 PolarHBondContact NE2-OE1 3.22Å; T111-E114 PolarHBondContact O-N 2.78Å; Y112-E114 VanDerWaalsContact C-N 3.31Å; Y112-E114 PolarHBondContact O-N 3.06Å; E114-R117 PolarHBondContact O-N 3.12Å; E114-R117 IonicContact OE2-CZ 3.38Å; E114-R117 VanDerWaalsContact OE2-CZ 3.27Å; E114-R117 IonicContact OE2-NE 2.66Å; E114-R117 PolarHBondContact OE2-NE 3.24Å; E114-R117 IonicContact OE2-NH2 3.76Å; E114-R117 PolarHBondContact OE2-NH2 2.86Å; E114-M118 VanDerWaalsContact O-CB 3.27Å; E114-M118 WeakPolarHBondContact O-CB 3.41Å; E114-M118 PolarHBondContact O-N 3.37Å
115	V	97.7	Very high	95.1	Very high	0 Å²	0	33.6 Å²	33.6	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-61.6	-51.2	172.9	166.7	0	0	0	0	110.7	L67 T111 Y112 R117 M118 V119 F157 F158 F161	L67-V115 HydrophobicContact CD1-CG2 3.76Å; L67-V115 HydrophobicContact CD2-CG2 4.24Å; T111-V115 HydrophobicContact CG2-CG2 3.88Å; T111-V115 WeakPolarHBondContact O-CG2 3.15Å; T111-V115 PolarHBondContact O-N 3.35Å; Y112-V115 PolarHBondContact O-N 3.34Å; V115-R117 VanDerWaalsContact C-N 3.29Å; V115-R117 PolarHBondContact O-N 2.9Å; V115-M118 PolarHBondContact O-N 3.14Å; V115-V119 HydrophobicContact CG1-CG2 4.47Å; V115-V119 WeakPolarHBondContact O-CG2 3.34Å; V115-V119 PolarHBondContact O-N 3.07Å; V115-F157 HydrophobicContact CB-CE1 4.34Å; V115-F157 HydrophobicContact CG1-CE1 3.79Å; V115-F157 HydrophobicContact CG2-CE1 3.87Å; V115-F157 HydrophobicContact CG2-CZ 3.89Å; V115-F158 HydrophobicContact CG1-CD2 4.37Å; V115-F161 HydrophobicContact CB-CE2 4.35Å; V115-F161 HydrophobicContact CB-CZ 4.31Å; V115-F161 HydrophobicContact CG1-CB 4.44Å; V115-F161 HydrophobicContact CG1-CD1 3.67Å; V115-F161 HydrophobicContact CG1-CD2 4.04Å; V115-F161 HydrophobicContact CG1-CE1 3.72Å; V115-F161 HydrophobicContact CG1-CE2 4.12Å; V115-F161 HydrophobicContact CG1-CG 3.79Å; V115-F161 HydrophobicContact CG1-CZ 3.95Å; V115-F161 HydrophobicContact CG2-CD2 4.36Å; V115-F161 HydrophobicContact CG2-CE2 4.33Å
116	V	97.6	Very high	95.4	Very high	11 Å²	11	36.9 Å²	36.9	7%	0.067	19%	0.192	C	C	.	.	H	α-helix	trans	-62.4	-39.5	-179.3	173.1	0	0	0	0	110.8	Y112 P113 S120 I176 F180	Y112-V116 WeakPolarHBondContact O-CG2 3.29Å; Y112-V116 PolarHBondContact O-N 3.26Å; P113-V116 PolarHBondContact O-N 3.4Å; V116-S120 WeakPolarHBondContact O-CB 3.41Å; V116-S120 PolarHBondContact O-N 2.71Å; V116-S120 PolarHBondContact O-OG 2.95Å; V116-I176 HydrophobicContact CG2-CD1 4.41Å; V116-I176 HydrophobicContact CG2-CG1 3.95Å; V116-F180 HydrophobicContact CG1-CD2 3.95Å; V116-F180 HydrophobicContact CG1-CE2 3.88Å
117	R	97.6	Very high	95.5	Very high	92 Å²	92	38.5 Å²	38.5	35%	0.347	20%	0.2	S	C	.	.	H	α-helix	trans	-64.4	-46.1	175.8	-169.5	-179.8	69.1	69.9	14.2	111.7	Q68 C71 P113 E114 V115 S120 C121	Q68-R117 VanDerWaalsContact CG-NH2 3.32Å; C71-R117 PolarHBondContact SG-NH1 3Å; C71-R117 PolarHBondContact SG-NH2 3.17Å; P113-R117 WeakPolarHBondContact O-CB 3.33Å; P113-R117 PolarHBondContact O-N 2.87Å; E114-R117 PolarHBondContact O-N 3.12Å; E114-R117 IonicContact OE2-CZ 3.38Å; E114-R117 VanDerWaalsContact OE2-CZ 3.27Å; E114-R117 IonicContact OE2-NE 2.66Å; E114-R117 PolarHBondContact OE2-NE 3.24Å; E114-R117 IonicContact OE2-NH2 3.76Å; E114-R117 PolarHBondContact OE2-NH2 2.86Å; V115-R117 VanDerWaalsContact C-N 3.29Å; V115-R117 PolarHBondContact O-N 2.9Å; R117-S120 PolarHBondContact O-N 2.92Å; R117-C121 WeakPolarHBondContact O-CB 3.18Å; R117-C121 PolarHBondContact O-N 3.49Å; R117-C121 PolarHBondContact O-SG 3.21Å
118	M	97.7	Very high	95.2	Very high	0 Å²	0	40.7 Å²	40.7	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-59.1	-48.8	177.2	-172.1	-77.7	-70.8	0	0	111.5	L67 C70 C71 L93 E114 V115 N122 V154 F157	L67-M118 HydrophobicContact CD2-CB 4.4Å; L67-M118 HydrophobicContact CD2-CE 3.98Å; L67-M118 HydrophobicContact CD2-CG 4.36Å; L67-M118 WeakPolarHBondContact O-CG 3.5Å; C70-M118 HydrophobicContact CB-CG 3.77Å; C70-M118 HydrophobicContact CB-SD 4.22Å; C71-M118 VanDerWaalsContact SG-CA 3.51Å; L93-M118 HydrophobicContact CD2-CE 4.45Å; L93-M118 HydrophobicContact CD2-SD 4.22Å; E114-M118 VanDerWaalsContact O-CB 3.27Å; E114-M118 WeakPolarHBondContact O-CB 3.41Å; E114-M118 PolarHBondContact O-N 3.37Å; V115-M118 PolarHBondContact O-N 3.14Å; M118-N122 PolarHBondContact O-N 3.32Å; M118-N122 PolarHBondContact O-ND2 2.96Å; M118-V154 HydrophobicContact SD-CG1 4.18Å; M118-V154 HydrophobicContact SD-CG2 4.08Å; M118-F157 HydrophobicContact CE-CD1 3.36Å; M118-F157 HydrophobicContact CE-CE1 3.58Å; M118-F157 HydrophobicContact CE-CG 4.18Å
119	V	98	Very high	94.6	Very high	1 Å²	1	42.3 Å²	42.3	1%	0.006	23%	0.227	C	C	.	.	H	α-helix	trans	-60.9	-51.3	176.6	172.7	0	0	0	0	110.4	V115 C121 N122 I123 V154 F158 F180	V115-V119 HydrophobicContact CG1-CG2 4.47Å; V115-V119 WeakPolarHBondContact O-CG2 3.34Å; V115-V119 PolarHBondContact O-N 3.07Å; V119-C121 PolarHBondContact O-N 2.94Å; V119-N122 PolarHBondContact O-N 2.88Å; V119-I123 HydrophobicContact CG1-CD1 3.53Å; V119-I123 HydrophobicContact CG1-CG1 4.03Å; V119-I123 HydrophobicContact CG1-CG2 4.39Å; V119-I123 WeakPolarHBondContact O-CG1 3.34Å; V119-I123 PolarHBondContact O-N 3.5Å; V119-V154 HydrophobicContact CG2-CG1 4.24Å; V119-F158 HydrophobicContact CG1-CD1 4.03Å; V119-F158 HydrophobicContact CG1-CD2 4.38Å; V119-F158 HydrophobicContact CG1-CE1 4.3Å; V119-F158 HydrophobicContact CG1-CG 4.08Å; V119-F158 HydrophobicContact CG2-CB 3.86Å; V119-F158 HydrophobicContact CG2-CD2 3.72Å; V119-F158 HydrophobicContact CG2-CE2 4.42Å; V119-F158 HydrophobicContact CG2-CG 3.84Å; V119-F180 HydrophobicContact CG1-CZ 4.43Å
120	S	97.4	Very high	93.7	Very high	29 Å²	29	38.6 Å²	38.6	20%	0.203	22%	0.215	C	C	.	.	H	α-helix	trans	-58.5	-43.7	-177.4	-59.3	0	0	0	0	112.9	V116 R117 N122 F124	V116-S120 WeakPolarHBondContact O-CB 3.41Å; V116-S120 PolarHBondContact O-N 2.71Å; V116-S120 PolarHBondContact O-OG 2.95Å; R117-S120 PolarHBondContact O-N 2.92Å; S120-N122 PolarHBondContact O-N 3.18Å; S120-F124 WeakPolarHBondContact O-CB 3.2Å; S120-F124 PolarHBondContact O-N 2.95Å; S120-F124 WeakPolarHBondContact OG-CE2 3.27Å
121	C	96.2	Very high	92	Very high	48 Å²	48	38 Å²	38	32%	0.324	22%	0.216	S	C	.	.	H	α-helix	trans	-63.2	-30.7	178.3	-72.8	0	0	0	0	112.9	C71 I73 R117 V119	C71-C121 HydrophobicContact CB-CB 4.31Å; I73-C121 WeakPolarHBondContact CD1-O 3.5Å; R117-C121 WeakPolarHBondContact O-CB 3.18Å; R117-C121 PolarHBondContact O-N 3.49Å; R117-C121 PolarHBondContact O-SG 3.21Å; V119-C121 PolarHBondContact O-N 2.94Å
122	N	97	Very high	90.1	Very high	10 Å²	10	40.8 Å²	40.8	5%	0.053	24%	0.236	C	C	.	.	H	α-helix	trans	-89.8	-45.1	-176.4	-77.9	-86.9	0	0	0	112.6	C70 I73 K89 M118 V119 S120 L151 V154	C70-N122 PolarHBondContact O-ND2 2.92Å; I73-N122 HydrophobicContact CD1-CB 4.17Å; I73-N122 VanDerWaalsContact CD1-CG 3.5Å; I73-N122 WeakPolarHBondContact CD1-OD1 3.35Å; K89-N122 PolarHBondContact NZ-OD1 3.19Å; M118-N122 PolarHBondContact O-N 3.32Å; M118-N122 PolarHBondContact O-ND2 2.96Å; V119-N122 PolarHBondContact O-N 2.88Å; S120-N122 PolarHBondContact O-N 3.18Å; N122-L151 HydrophobicContact CB-CD2 4.4Å; N122-L151 WeakPolarHBondContact O-CD2 3.48Å; N122-V154 HydrophobicContact CB-CB 4.49Å; N122-V154 HydrophobicContact CB-CG1 4.01Å; N122-V154 HydrophobicContact CB-CG2 3.98Å
123	I	96.8	Very high	88.2	Confident	0 Å²	0	49.3 Å²	49.3	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-90.4	-37.8	-170.9	74.3	175.3	0	0	0	112.9	V119 R125 L151 V154 Y155 L184 L187	V119-I123 HydrophobicContact CG1-CD1 3.53Å; V119-I123 HydrophobicContact CG1-CG1 4.03Å; V119-I123 HydrophobicContact CG1-CG2 4.39Å; V119-I123 WeakPolarHBondContact O-CG1 3.34Å; V119-I123 PolarHBondContact O-N 3.5Å; I123-R125 PolarHBondContact O-N 3Å; I123-R125 PolarHBondContact O-NH1 3.41Å; I123-L151 HydrophobicContact CG2-CD2 4.38Å; I123-V154 HydrophobicContact CG2-CG1 3.85Å; I123-Y155 HydrophobicContact CB-CE1 4.47Å; I123-Y155 HydrophobicContact CD1-CE1 4.24Å; I123-Y155 HydrophobicContact CG2-CE1 4.01Å; I123-Y155 HydrophobicContact CG2-CE2 4.22Å; I123-L184 HydrophobicContact CD1-CD1 3.93Å; I123-L187 HydrophobicContact CB-CD1 4Å; I123-L187 HydrophobicContact CD1-CD1 4.18Å; I123-L187 HydrophobicContact CG1-CD1 3.98Å; I123-L187 WeakPolarHBondContact O-CD1 3.39Å; I123-L187 WeakPolarHBondContact O-CD2 3.42Å
124	F	96.7	Very high	86.4	Confident	23 Å²	23	54.9 Å²	54.9	10%	0.101	30%	0.304	C	S	.	.			trans	-78.8	101.9	-173.6	-60.2	-36.5	0	0	0	110.5	Q35 S120 F180 Q183 L184 L187	Q35-F124 PolarHBondContact NE2-O 2.67Å; S120-F124 WeakPolarHBondContact O-CB 3.2Å; S120-F124 PolarHBondContact O-N 2.95Å; S120-F124 WeakPolarHBondContact OG-CE2 3.27Å; F124-F180 AromaticContact CE2-CD2 3.53Å; F124-F180 HydrophobicContact CE2-CD2 3.53Å; F124-F180 AromaticContact CE2-CE2 3.56Å; F124-F180 HydrophobicContact CE2-CE2 3.56Å; F124-F180 HydrophobicContact CE2-CG 4.21Å; F124-F180 HydrophobicContact CE2-CZ 4.26Å; F124-F180 HydrophobicContact CZ-CD1 4.16Å; F124-F180 AromaticContact CZ-CD2 3.61Å; F124-F180 HydrophobicContact CZ-CD2 3.61Å; F124-F180 HydrophobicContact CZ-CE1 4.05Å; F124-F180 AromaticContact CZ-CE2 3.48Å; F124-F180 HydrophobicContact CZ-CE2 3.48Å; F124-F180 VanDerWaalsContact CZ-CE2 3.48Å; F124-F180 AromaticContact CZ-CG 3.95Å; F124-F180 HydrophobicContact CZ-CG 3.95Å; F124-F180 AromaticContact CZ-CZ 3.72Å; F124-F180 HydrophobicContact CZ-CZ 3.72Å; F124-Q183 HydrophobicContact CD1-CB 3.62Å; F124-Q183 HydrophobicContact CD2-CB 4.15Å; F124-Q183 HydrophobicContact CE1-CB 3.76Å; F124-Q183 HydrophobicContact CE2-CB 4.24Å; F124-Q183 HydrophobicContact CG-CB 3.88Å; F124-Q183 HydrophobicContact CZ-CB 4.06Å; F124-L184 HydrophobicContact CE1-CB 4.03Å; F124-L184 HydrophobicContact CE1-CD1 4.3Å; F124-L184 HydrophobicContact CZ-CB 4.47Å; F124-L187 HydrophobicContact CD1-CD1 3.87Å; F124-L187 HydrophobicContact CE1-CD1 4.24Å
125	R	94.1	Very high	84.8	Confident	29 Å²	29	55.1 Å²	55.1	11%	0.109	31%	0.305	C	S	.	.			trans	-142.3	156	178.6	68.7	-163.5	-173.8	-66.5	-2.4	109.1	I123 L127 E145 E195	I123-R125 PolarHBondContact O-N 3Å; I123-R125 PolarHBondContact O-NH1 3.41Å; R125-L127 PolarHBondContact O-N 3.41Å; R125-E145 IonicContact CZ-OE2 3.15Å; R125-E145 VanDerWaalsContact CZ-OE2 3.31Å; R125-E145 IonicContact NE-OE2 3.6Å; R125-E145 PolarHBondContact NE-OE2 3.04Å; R125-E145 IonicContact NH2-OE2 3.06Å; R125-E145 PolarHBondContact NH2-OE2 3.22Å; R125-E195 IonicContact CZ-OE1 2.65Å; R125-E195 IonicContact CZ-OE2 3.98Å; R125-E195 IonicContact NH1-OE1 2.94Å; R125-E195 PolarHBondContact NH1-OE1 2.89Å; R125-E195 IonicContact NH1-OE2 3.8Å; R125-E195 IonicContact NH2-OE1 3.9Å; R125-E195 PolarHBondContact NH2-OE1 2.92Å; R125-E195 VanDerWaalsContact NH2-OE1 3.09Å; R125-E195 IonicContact NH2-OE2 3.1Å; R125-E195 PolarHBondContact NH2-OE2 3Å
126	T	91.7	Very high	83.5	Confident	119 Å²	119	58 Å²	58	73%	0.73	32%	0.32	S	S	*	.	P	Polyproline II helix	trans	-70.2	124.2	166.2	-53.7	0	0	0	0	107.9
127	L	90.9	Very high	82	Confident	35 Å²	35	60.1 Å²	60.1	18%	0.183	33%	0.334	C	S	.	.	P	Polyproline II helix	trans	-64.1	147	175.8	-64.9	173.3	0	0	0	110.2	R125 L187 D189 S190	R125-L127 PolarHBondContact O-N 3.41Å; L127-L187 HydrophobicContact CD2-CD2 4.27Å; L127-D189 VanDerWaalsContact CD1-C 3.42Å; L127-D189 HydrophobicContact CD1-CB 3.84Å; L127-S190 VanDerWaalsContact CD1-N 3.33Å
128	P	85.1	Confident	80.6	Confident	60 Å²	60	60.7 Å²	60.7	39%	0.39	34%	0.341	S	S	.	.	P	Polyproline II helix	trans	-59.4	149.4	174.1	27.2	-34	0	0	0	110.1
129	P	80.2	Confident	79.5	Confident	89 Å²	89	68.3 Å²	68.3	58%	0.578	38%	0.376	S	S	*	.	P	Polyproline II helix	trans	-61.4	140.9	173.7	27.8	-33.9	0	0	0	109.9	D131	P129-D131 PolarHBondContact O-N 3.28Å
130	S	72.5	Confident	78.5	Confident	48 Å²	48	71.8 Å²	71.8	34%	0.336	40%	0.395	S	S	.	.	P	Polyproline II helix	trans	-68.8	125.6	172.5	44	0	0	0	0	110.1	S132 E191	S130-S132 VanDerWaalsContact C-N 3.35Å; S130-S132 PolarHBondContact O-N 3.35Å; S130-E191 WeakPolarHBondContact CB-OE1 3.38Å
131	D	57.9	Low	77.7	Confident	124 Å²	124	79.1 Å²	79.1	66%	0.663	43%	0.426	S	S	*	.	S	Bend	trans	-79.3	85.5	-179.7	-88.1	-22.1	0	0	0	109.2	P129	P129-D131 PolarHBondContact O-N 3.28Å
132	S	56.4	Low	77	Confident	61 Å²	61	79.5 Å²	79.5	43%	0.427	43%	0.428	S	S	.	.			trans	104.7	135.8	168.9	86.3	0	0	0	0	116.9	S130 E134 F135	S130-S132 VanDerWaalsContact C-N 3.35Å; S130-S132 PolarHBondContact O-N 3.35Å; S132-E134 PolarHBondContact O-N 3.35Å; S132-E134 VanDerWaalsContact O-N 3.11Å; S132-E134 PolarHBondContact OG-N 2.81Å; S132-F135 PolarHBondContact O-N 2.92Å; S132-F135 PolarHBondContact OG-N 3.14Å
133	N	56.9	Low	76.4	Confident	180 Å²	180	82.1 Å²	82.1	96%	0.963	44%	0.444	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.1	0.7	164.8	-63.9	-15.2	0	0	0	112.8
134	E	59.5	Low	76.1	Confident	156 Å²	156	86.7 Å²	86.7	73%	0.729	47%	0.468	S	S	*	.	T	Hydrogen-bonded Turn	trans	-105.4	1.2	179.1	-67.1	-170.2	161.2	0	0	112.2	S132 D136	S132-E134 PolarHBondContact O-N 3.35Å; S132-E134 VanDerWaalsContact O-N 3.11Å; S132-E134 PolarHBondContact OG-N 2.81Å; E134-D136 PolarHBondContact O-N 3.38Å; E134-D136 VanDerWaalsContact O-N 3.08Å
135	F	62.7	Low	75.8	Confident	43 Å²	43	87.5 Å²	87.5	19%	0.189	47%	0.472	C	S	.	.			trans	-56.4	117.6	174.8	-179.5	-100.5	0	0	0	109	S132 P137 D140	S132-F135 PolarHBondContact O-N 2.92Å; S132-F135 PolarHBondContact OG-N 3.14Å; F135-P137 HydrophobicContact CD1-CB 4.36Å; F135-P137 HydrophobicContact CD1-CG 3.79Å; F135-P137 HydrophobicContact CE1-CB 3.79Å; F135-P137 HydrophobicContact CE1-CG 3.7Å; F135-P137 WeakPolarHBondContact O-CD 3.34Å; F135-D140 WeakPolarHBondContact CA-OD2 3.47Å; F135-D140 HydrophobicContact CD2-CB 3.45Å; F135-D140 VanDerWaalsContact CD2-CB 3.45Å; F135-D140 HydrophobicContact CE2-CB 3.23Å; F135-D140 HydrophobicContact CG-CB 4.4Å; F135-D140 HydrophobicContact CZ-CB 4.03Å
136	D	69.7	Low	75.6	Confident	59 Å²	59	88 Å²	88	32%	0.316	48%	0.483	S	S	.	.			trans	-98.2	105.3	172.2	-170.6	-20.4	0	0	0	107.6	E134 E138 E139 D140	E134-D136 PolarHBondContact O-N 3.38Å; E134-D136 VanDerWaalsContact O-N 3.08Å; D136-E138 PolarHBondContact O-N 2.87Å; D136-E138 WeakPolarHBondContact OD1-CB 3.38Å; D136-E138 PolarHBondContact OD1-N 2.96Å; D136-E139 HydrophobicContact CB-CB 4.18Å; D136-E139 HydrophobicContact CB-CG 4.44Å; D136-E139 PolarHBondContact O-N 3.43Å; D136-D140 PolarHBondContact N-OD2 3.25Å; D136-D140 WeakPolarHBondContact O-CB 3.36Å; D136-D140 PolarHBondContact O-N 3.37Å
137	P	66.8	Low	75.7	Confident	57 Å²	57	83 Å²	83	37%	0.37	45%	0.453	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.5	-14.5	-178.9	-20	33.3	0	0	0	113.5	F135 L279	F135-P137 HydrophobicContact CD1-CB 4.36Å; F135-P137 HydrophobicContact CD1-CG 3.79Å; F135-P137 HydrophobicContact CE1-CB 3.79Å; F135-P137 HydrophobicContact CE1-CG 3.7Å; F135-P137 WeakPolarHBondContact O-CD 3.34Å; P137-L279 HydrophobicContact CB-CD1 3.53Å; P137-L279 HydrophobicContact CB-CD2 3.99Å; P137-L279 HydrophobicContact CB-CG 4.42Å; P137-L279 HydrophobicContact CG-CD1 3.58Å
138	E	68.8	Low	75.9	Confident	104 Å²	104	82.3 Å²	82.3	49%	0.486	45%	0.448	S	S	.	.	T	Hydrogen-bonded Turn	trans	-83.8	-27.2	174	-58.3	-167.4	149.9	0	0	113	D136 S278 L279	D136-E138 PolarHBondContact O-N 2.87Å; D136-E138 WeakPolarHBondContact OD1-CB 3.38Å; D136-E138 PolarHBondContact OD1-N 2.96Å; E138-S278 WeakPolarHBondContact OE1-CB 3.34Å; E138-S278 PolarHBondContact OE1-OG 3.15Å; E138-L279 HydrophobicContact CG-CD2 3.78Å
139	E	73.8	Confident	76.4	Confident	160 Å²	160	82.3 Å²	82.3	75%	0.748	45%	0.447	S	S	*	.	T	Hydrogen-bonded Turn	trans	-109.2	-31.6	-175.7	-61.7	-164.4	164	0	0	114.1	D136	D136-E139 HydrophobicContact CB-CB 4.18Å; D136-E139 HydrophobicContact CB-CG 4.44Å; D136-E139 PolarHBondContact O-N 3.43Å
140	D	77.6	Confident	77.2	Confident	74 Å²	74	78.3 Å²	78.3	40%	0.396	42%	0.421	S	S	.	.	S	Bend	trans	-92.2	142.1	-170.7	-70.4	-44.1	0	0	0	112.8	F135 D136	F135-D140 WeakPolarHBondContact CA-OD2 3.47Å; F135-D140 HydrophobicContact CD2-CB 3.45Å; F135-D140 VanDerWaalsContact CD2-CB 3.45Å; F135-D140 HydrophobicContact CE2-CB 3.23Å; F135-D140 HydrophobicContact CG-CB 4.4Å; F135-D140 HydrophobicContact CZ-CB 4.03Å; D136-D140 PolarHBondContact N-OD2 3.25Å; D136-D140 WeakPolarHBondContact O-CB 3.36Å; D136-D140 PolarHBondContact O-N 3.37Å
141	E	79.7	Confident	78.4	Confident	182 Å²	182	76.2 Å²	76.2	85%	0.85	41%	0.406	S	S	*	.	P	Polyproline II helix	trans	-71.6	133.7	174.7	-70.5	-175.9	175.7	0	0	110.8
142	P	83.2	Confident	80.3	Confident	57 Å²	57	73.9 Å²	73.9	37%	0.37	39%	0.391	S	S	.	.	P	Polyproline II helix	trans	-70.1	146.1	-178.3	28.4	-34.7	0	0	0	112	L144 E191	P142-L144 PolarHBondContact O-N 3.31Å; P142-E191 WeakPolarHBondContact CB-O 3.39Å
143	T	84	Confident	82.3	Confident	65 Å²	65	71.8 Å²	71.8	40%	0.399	38%	0.375	S	S	.	.			trans	-71.4	113	171.5	-53.7	0	0	0	0	110.3	E191	T143-E191 WeakPolarHBondContact CB-OE2 3.3Å; T143-E191 PolarHBondContact N-OE2 3.15Å; T143-E191 PolarHBondContact OG1-OE2 2.89Å
144	L	89.9	Confident	84.3	Confident	95 Å²	95	63.2 Å²	63.2	50%	0.497	33%	0.329	S	S	.	.			trans	-79.8	141.1	176.6	-60	-174.8	0	0	0	111.7	P142 A146	P142-L144 PolarHBondContact O-N 3.31Å; L144-A146 PolarHBondContact O-N 2.81Å
145	E	89.5	Confident	86.1	Confident	40 Å²	40	55.8 Å²	55.8	19%	0.187	30%	0.295	C	S	.	.			trans	-72.4	122.9	178.8	175.7	51.7	-110.4	0	0	111.1	R125 S147 W148 L151 D192	R125-E145 IonicContact CZ-OE2 3.15Å; R125-E145 VanDerWaalsContact CZ-OE2 3.31Å; R125-E145 IonicContact NE-OE2 3.6Å; R125-E145 PolarHBondContact NE-OE2 3.04Å; R125-E145 IonicContact NH2-OE2 3.06Å; R125-E145 PolarHBondContact NH2-OE2 3.22Å; E145-S147 VanDerWaalsContact C-N 3.28Å; E145-S147 PolarHBondContact O-N 3.49Å; E145-S147 PolarHBondContact OE1-N 3.31Å; E145-S147 PolarHBondContact OE1-OG 3.48Å; E145-W148 WeakPolarHBondContact O-CB 3.32Å; E145-W148 PolarHBondContact O-N 3.41Å; E145-W148 VanDerWaalsContact O-N 3.17Å; E145-L151 HydrophobicContact CG-CD1 3.43Å; E145-L151 VanDerWaalsContact CG-CD1 3.43Å; E145-D192 PolarHBondContact N-OD2 2.88Å
146	A	91.4	Very high	87.8	Confident	40 Å²	40	56 Å²	56	33%	0.331	30%	0.296	S	S	.	.	T	Hydrogen-bonded Turn	trans	-65.3	-32.5	-175.3	0	0	0	0	0	112.4	F76 M77 L144 W148	F76-A146 HydrophobicContact CB-CB 3.94Å; F76-A146 WeakPolarHBondContact CB-O 3.45Å; F76-A146 WeakPolarHBondContact CD1-O 3.33Å; M77-A146 HydrophobicContact SD-CB 4.06Å; L144-A146 PolarHBondContact O-N 2.81Å; A146-W148 PolarHBondContact O-N 3.46Å
147	S	93.4	Very high	89.2	Confident	15 Å²	15	53.2 Å²	53.2	11%	0.105	28%	0.281	C	S	.	.	T	Hydrogen-bonded Turn	trans	-83.7	8.8	178.8	62.5	0	0	0	0	114.3	E145 P149 H150 L151	E145-S147 VanDerWaalsContact C-N 3.28Å; E145-S147 PolarHBondContact O-N 3.49Å; E145-S147 PolarHBondContact OE1-N 3.31Å; E145-S147 PolarHBondContact OE1-OG 3.48Å; S147-P149 VanDerWaalsContact C-N 3.32Å; S147-P149 VanDerWaalsContact O-N 3.13Å; S147-H150 PolarHBondContact O-N 3.49Å; S147-L151 PolarHBondContact O-N 3.3Å; S147-L151 VanDerWaalsContact O-N 3.09Å; S147-L151 VanDerWaalsContact OG-CD1 3.3Å; S147-L151 WeakPolarHBondContact OG-CD1 3.28Å
148	W	95.6	Very high	90.7	Very high	20 Å²	20	50.5 Å²	50.5	8%	0.076	26%	0.264	C	S	.	.	H	α-helix	trans	-47.6	-40.7	-178.3	-169.2	-108	0	0	0	115.3	E145 A146 H150 L151 Q152 Y155 R194 E195 Y198	E145-W148 WeakPolarHBondContact O-CB 3.32Å; E145-W148 PolarHBondContact O-N 3.41Å; E145-W148 VanDerWaalsContact O-N 3.17Å; A146-W148 PolarHBondContact O-N 3.46Å; W148-H150 PolarHBondContact O-N 3.12Å; W148-H150 VanDerWaalsContact O-N 3.09Å; W148-L151 HydrophobicContact CE3-CB 4.26Å; W148-L151 HydrophobicContact CZ3-CB 4.5Å; W148-L151 PolarHBondContact O-N 3.34Å; W148-Q152 HydrophobicContact CD2-CB 4.37Å; W148-Q152 HydrophobicContact CZ2-CB 4.03Å; W148-Q152 HydrophobicContact CZ2-CG 4.18Å; W148-Q152 VanDerWaalsContact O-CB 3.3Å; W148-Q152 WeakPolarHBondContact O-CB 3.17Å; W148-Q152 PolarHBondContact O-N 3.47Å; W148-Y155 HydrophobicContact CZ3-CD2 4.47Å; W148-Y155 HydrophobicContact CZ3-CE2 4.5Å; W148-R194 VanDerWaalsContact CD1-CZ 3.49Å; W148-R194 VanDerWaalsContact CD1-NH1 3.27Å; W148-R194 VanDerWaalsContact CH2-C 3.45Å; W148-R194 HydrophobicContact CH2-CB 3.61Å; W148-R194 HydrophobicContact CZ2-CB 3.34Å; W148-R194 HydrophobicContact CZ2-CG 4.41Å; W148-R194 HydrophobicContact CZ3-CB 4.32Å; W148-E195 HydrophobicContact CH2-CB 4.34Å; W148-E195 HydrophobicContact CZ3-CB 3.75Å; W148-E195 HydrophobicContact CZ3-CG 4.35Å; W148-Y198 AromaticContact CH2-CD2 3.71Å; W148-Y198 HydrophobicContact CH2-CD2 3.71Å; W148-Y198 HydrophobicContact CH2-CE2 4.07Å; W148-Y198 AromaticContact CZ2-CD2 3.98Å; W148-Y198 HydrophobicContact CZ2-CD2 3.98Å; W148-Y198 AromaticContact CZ2-CE2 3.86Å; W148-Y198 HydrophobicContact CZ2-CE2 3.86Å
149	P	95	Very high	92.1	Very high	59 Å²	59	46.5 Å²	46.5	38%	0.383	25%	0.245	S	C	.	.	H	α-helix	trans	-58.1	-25.6	178.1	-26.4	36.1	0	0	0	114.8	F76 S147	F76-P149 HydrophobicContact CE1-CB 4.5Å; F76-P149 HydrophobicContact CE1-CG 4.36Å; S147-P149 VanDerWaalsContact C-N 3.32Å; S147-P149 VanDerWaalsContact O-N 3.13Å
150	H	96.9	Very high	93.2	Very high	6 Å²	6	42.9 Å²	42.9	3%	0.028	23%	0.225	C	C	.	.	H	α-helix	trans	-92.1	-45.9	171.8	-73.1	-176.3	0	0	0	111.4	F74 F76 K86 L93 S147 W148 Q152 L153 V154	F74-H150 AromaticContact CD2-CE1 3.75Å; F76-H150 HydrophobicContact CE2-CB 4.42Å; F76-H150 AromaticContact CE2-CE1 3.78Å; F76-H150 AromaticContact CE2-CG 3.87Å; F76-H150 AromaticContact CE2-ND1 3.47Å; F76-H150 WeakPolarHBondContact CE2-ND1 3.27Å; F76-H150 HydrophobicContact CZ-CB 4.42Å; F76-H150 AromaticContact CZ-CD2 3.75Å; F76-H150 AromaticContact CZ-CE1 3.53Å; F76-H150 AromaticContact CZ-CG 3.66Å; F76-H150 AromaticContact CZ-ND1 3.56Å; F76-H150 AromaticContact CZ-NE2 3.67Å; K86-H150 PolarHBondContact O-CE1 3.19Å; K86-H150 PolarHBondContact O-NE2 3.43Å; L93-H150 HydrophobicContact CD1-CB 4.21Å; S147-H150 PolarHBondContact O-N 3.49Å; W148-H150 PolarHBondContact O-N 3.12Å; W148-H150 VanDerWaalsContact O-N 3.09Å; H150-Q152 VanDerWaalsContact C-N 3.33Å; H150-Q152 PolarHBondContact O-N 3Å; H150-L153 PolarHBondContact O-N 3.07Å; H150-V154 WeakPolarHBondContact O-CG2 3.18Å; H150-V154 PolarHBondContact O-N 3.31Å; H150-V154 VanDerWaalsContact O-N 3.07Å
151	L	97.1	Very high	94.1	Very high	4 Å²	4	39.3 Å²	39.3	2%	0.021	21%	0.206	C	C	.	.	H	α-helix	trans	-61	-40.5	-176.2	-68.7	-179.3	0	0	0	112.8	N122 I123 E145 S147 W148 L153 V154 Y155	N122-L151 HydrophobicContact CB-CD2 4.4Å; N122-L151 WeakPolarHBondContact O-CD2 3.48Å; I123-L151 HydrophobicContact CG2-CD2 4.38Å; E145-L151 HydrophobicContact CG-CD1 3.43Å; E145-L151 VanDerWaalsContact CG-CD1 3.43Å; S147-L151 PolarHBondContact O-N 3.3Å; S147-L151 VanDerWaalsContact O-N 3.09Å; S147-L151 VanDerWaalsContact OG-CD1 3.3Å; S147-L151 WeakPolarHBondContact OG-CD1 3.28Å; W148-L151 HydrophobicContact CE3-CB 4.26Å; W148-L151 HydrophobicContact CZ3-CB 4.5Å; W148-L151 PolarHBondContact O-N 3.34Å; L151-L153 VanDerWaalsContact C-N 3.29Å; L151-L153 PolarHBondContact O-N 2.74Å; L151-V154 PolarHBondContact O-N 3Å; L151-V154 VanDerWaalsContact O-N 3.12Å; L151-Y155 HydrophobicContact CB-CD2 4.41Å; L151-Y155 HydrophobicContact CB-CE2 4.36Å; L151-Y155 WeakPolarHBondContact O-CD2 3.34Å; L151-Y155 PolarHBondContact O-N 3.24Å
152	Q	98.1	Very high	95	Very high	74 Å²	74	30.7 Å²	30.7	35%	0.346	17%	0.165	S	C	.	.	H	α-helix	trans	-53.6	-47.9	176.5	-176.5	-177.4	-5	0	0	111.4	W148 H150 Y155 E156 Y198	W148-Q152 HydrophobicContact CD2-CB 4.37Å; W148-Q152 HydrophobicContact CZ2-CB 4.03Å; W148-Q152 HydrophobicContact CZ2-CG 4.18Å; W148-Q152 VanDerWaalsContact O-CB 3.3Å; W148-Q152 WeakPolarHBondContact O-CB 3.17Å; W148-Q152 PolarHBondContact O-N 3.47Å; H150-Q152 VanDerWaalsContact C-N 3.33Å; H150-Q152 PolarHBondContact O-N 3Å; Q152-Y155 PolarHBondContact O-N 3.08Å; Q152-E156 WeakPolarHBondContact O-CB 3.18Å; Q152-E156 PolarHBondContact O-N 2.98Å; Q152-Y198 HydrophobicContact CG-CE2 4.19Å
153	L	98.3	Very high	95.6	Very high	17 Å²	17	31.7 Å²	31.7	9%	0.089	17%	0.165	C	C	.	.	H	α-helix	trans	-69.8	-34.2	-179.9	-63.5	172.6	0	0	0	112.1	R90 L93 N94 H150 L151 F157	R90-L153 HydrophobicContact CG-CD1 3.75Å; R90-L153 WeakPolarHBondContact O-CD1 3.48Å; L93-L153 HydrophobicContact CB-CB 3.77Å; L93-L153 HydrophobicContact CB-CD1 3.79Å; L93-L153 HydrophobicContact CB-CG 4.43Å; L93-L153 HydrophobicContact CD1-CB 4.24Å; N94-L153 HydrophobicContact CB-CD1 4.5Å; H150-L153 PolarHBondContact O-N 3.07Å; L151-L153 VanDerWaalsContact C-N 3.29Å; L151-L153 PolarHBondContact O-N 2.74Å; L153-F157 WeakPolarHBondContact O-CB 3.02Å; L153-F157 PolarHBondContact O-N 2.92Å
154	V	98.5	Very high	96.1	Very high	0 Å²	0	29.6 Å²	29.6	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-64.9	-44.8	174.6	173.9	0	0	0	0	110.8	L93 M118 V119 N122 I123 H150 L151 F158	L93-V154 HydrophobicContact CD1-CG2 4.04Å; L93-V154 HydrophobicContact CD2-CG2 3.9Å; M118-V154 HydrophobicContact SD-CG1 4.18Å; M118-V154 HydrophobicContact SD-CG2 4.08Å; V119-V154 HydrophobicContact CG2-CG1 4.24Å; N122-V154 HydrophobicContact CB-CB 4.49Å; N122-V154 HydrophobicContact CB-CG1 4.01Å; N122-V154 HydrophobicContact CB-CG2 3.98Å; I123-V154 HydrophobicContact CG2-CG1 3.85Å; H150-V154 WeakPolarHBondContact O-CG2 3.18Å; H150-V154 PolarHBondContact O-N 3.31Å; H150-V154 VanDerWaalsContact O-N 3.07Å; L151-V154 PolarHBondContact O-N 3Å; L151-V154 VanDerWaalsContact O-N 3.12Å; V154-F158 WeakPolarHBondContact O-CB 3.2Å; V154-F158 PolarHBondContact O-N 3.12Å
155	Y	98.6	Very high	96.3	Very high	1 Å²	1	34.6 Å²	34.6	0%	0.004	17%	0.174	C	C	.	.	H	α-helix	trans	-65.2	-45.6	176	-79	-63.7	0	0	0	112.1	I123 W148 L151 Q152 F157 F158 I159 E195 Y198 L199 V202	I123-Y155 HydrophobicContact CB-CE1 4.47Å; I123-Y155 HydrophobicContact CD1-CE1 4.24Å; I123-Y155 HydrophobicContact CG2-CE1 4.01Å; I123-Y155 HydrophobicContact CG2-CE2 4.22Å; W148-Y155 HydrophobicContact CZ3-CD2 4.47Å; W148-Y155 HydrophobicContact CZ3-CE2 4.5Å; L151-Y155 HydrophobicContact CB-CD2 4.41Å; L151-Y155 HydrophobicContact CB-CE2 4.36Å; L151-Y155 WeakPolarHBondContact O-CD2 3.34Å; L151-Y155 PolarHBondContact O-N 3.24Å; Q152-Y155 PolarHBondContact O-N 3.08Å; Y155-F157 PolarHBondContact O-N 3.21Å; Y155-F158 PolarHBondContact O-N 2.67Å; Y155-I159 WeakPolarHBondContact O-CG1 3.22Å; Y155-I159 PolarHBondContact O-N 2.84Å; Y155-E195 HydrophobicContact CE2-CG 3.83Å; Y155-E195 WeakPolarHBondContact OH-CG 3.41Å; Y155-E195 PolarHBondContact OH-OE1 3.04Å; Y155-Y198 HydrophobicContact CD2-CG 4.46Å; Y155-Y198 HydrophobicContact CG-CD1 4.28Å; Y155-Y198 HydrophobicContact CG-CG 4.09Å; Y155-L199 HydrophobicContact CE1-CD2 3.77Å; Y155-L199 HydrophobicContact CE1-CG 4.14Å; Y155-V202 HydrophobicContact CD1-CG2 4.34Å
156	E	98.2	Very high	96.5	Very high	48 Å²	48	35.8 Å²	35.8	22%	0.224	18%	0.18	C	C	.	.	H	α-helix	trans	-59	-48.6	176.3	-178.5	168.4	-172.7	0	0	111.1	V97 Q152 F158 I159 R160 Y198	V97-E156 HydrophobicContact CG1-CG 3.92Å; V97-E156 HydrophobicContact CG2-CG 4.38Å; Q152-E156 WeakPolarHBondContact O-CB 3.18Å; Q152-E156 PolarHBondContact O-N 2.98Å; E156-F158 VanDerWaalsContact C-N 3.28Å; E156-F158 PolarHBondContact O-N 3.09Å; E156-I159 PolarHBondContact O-N 2.72Å; E156-R160 HydrophobicContact CG-CG 4.5Å; E156-R160 WeakPolarHBondContact O-CG 3.33Å; E156-R160 PolarHBondContact O-N 3.01Å; E156-R160 IonicContact OE1-CZ 3.08Å; E156-R160 IonicContact OE1-NH2 2.63Å; E156-R160 PolarHBondContact OE1-NH2 3.19Å; E156-Y198 HydrophobicContact CB-CE1 4.27Å
157	F	98.4	Very high	96.7	Very high	0 Å²	0	34.6 Å²	34.6	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-54.9	-45.2	174.9	175.8	-98.3	0	0	0	111.6	F63 L67 L96 V97 I100 V115 M118 L153 Y155 R160 F161	F63-F157 HydrophobicContact CE2-CE2 4.12Å; F63-F157 HydrophobicContact CE2-CZ 4.38Å; F63-F157 AromaticContact CZ-CE2 3.9Å; F63-F157 HydrophobicContact CZ-CE2 3.9Å; F63-F157 AromaticContact CZ-CZ 3.83Å; F63-F157 HydrophobicContact CZ-CZ 3.83Å; L67-F157 HydrophobicContact CD2-CE1 3.84Å; L67-F157 HydrophobicContact CD2-CE2 4.5Å; L67-F157 HydrophobicContact CD2-CZ 3.66Å; L96-F157 HydrophobicContact CB-CD2 3.89Å; L96-F157 HydrophobicContact CB-CE2 3.89Å; V97-F157 HydrophobicContact CG2-CB 3.75Å; V97-F157 HydrophobicContact CG2-CD2 4.47Å; I100-F157 HydrophobicContact CB-CD2 4.49Å; I100-F157 HydrophobicContact CB-CE2 3.99Å; I100-F157 HydrophobicContact CD1-CD2 4.45Å; I100-F157 HydrophobicContact CD1-CE2 3.73Å; I100-F157 HydrophobicContact CD1-CZ 3.85Å; I100-F157 HydrophobicContact CG1-CE2 4.49Å; I100-F157 HydrophobicContact CG2-CD2 3.87Å; I100-F157 HydrophobicContact CG2-CE2 3.88Å; V115-F157 HydrophobicContact CB-CE1 4.34Å; V115-F157 HydrophobicContact CG1-CE1 3.79Å; V115-F157 HydrophobicContact CG2-CE1 3.87Å; V115-F157 HydrophobicContact CG2-CZ 3.89Å; M118-F157 HydrophobicContact CE-CD1 3.36Å; M118-F157 HydrophobicContact CE-CE1 3.58Å; M118-F157 HydrophobicContact CE-CG 4.18Å; L153-F157 WeakPolarHBondContact O-CB 3.02Å; L153-F157 PolarHBondContact O-N 2.92Å; Y155-F157 PolarHBondContact O-N 3.21Å; F157-R160 PolarHBondContact O-N 3.35Å; F157-F161 WeakPolarHBondContact O-CB 3.39Å; F157-F161 PolarHBondContact O-N 3.4Å
158	F	98.3	Very high	96.8	Very high	0 Å²	0	38.4 Å²	38.4	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-68.2	-37.5	-179.1	-168.3	-135.4	0	0	0	112.7	V115 V119 V154 Y155 E156 F161 L162 I176 F180 V202 I206	V115-F158 HydrophobicContact CG1-CD2 4.37Å; V119-F158 HydrophobicContact CG1-CD1 4.03Å; V119-F158 HydrophobicContact CG1-CD2 4.38Å; V119-F158 HydrophobicContact CG1-CE1 4.3Å; V119-F158 HydrophobicContact CG1-CG 4.08Å; V119-F158 HydrophobicContact CG2-CB 3.86Å; V119-F158 HydrophobicContact CG2-CD2 3.72Å; V119-F158 HydrophobicContact CG2-CE2 4.42Å; V119-F158 HydrophobicContact CG2-CG 3.84Å; V154-F158 WeakPolarHBondContact O-CB 3.2Å; V154-F158 PolarHBondContact O-N 3.12Å; Y155-F158 PolarHBondContact O-N 2.67Å; E156-F158 VanDerWaalsContact C-N 3.28Å; E156-F158 PolarHBondContact O-N 3.09Å; F158-F161 AromaticContact CD2-CD1 3.71Å; F158-F161 HydrophobicContact CD2-CD1 3.71Å; F158-F161 HydrophobicContact CD2-CE1 4.4Å; F158-F161 AromaticContact CE2-CD1 3.71Å; F158-F161 HydrophobicContact CE2-CD1 3.71Å; F158-F161 AromaticContact CE2-CE1 3.98Å; F158-F161 HydrophobicContact CE2-CE1 3.98Å; F158-F161 WeakPolarHBondContact O-CB 3.46Å; F158-F161 PolarHBondContact O-N 3.4Å; F158-L162 HydrophobicContact CD1-CD1 4.11Å; F158-L162 HydrophobicContact CD2-CG 4.4Å; F158-L162 HydrophobicContact CE1-CD1 3.89Å; F158-L162 HydrophobicContact CE2-CD1 4.4Å; F158-L162 HydrophobicContact CE2-CD2 4.29Å; F158-L162 HydrophobicContact CE2-CG 4.2Å; F158-L162 HydrophobicContact CG-CD1 4.47Å; F158-L162 HydrophobicContact CZ-CD1 4.03Å; F158-L162 HydrophobicContact CZ-CD2 4.28Å; F158-L162 HydrophobicContact CZ-CG 4.27Å; F158-L162 VanDerWaalsContact O-CG 3.3Å; F158-L162 WeakPolarHBondContact O-CG 3.5Å; F158-L162 PolarHBondContact O-N 3.45Å; F158-I176 HydrophobicContact CE2-CD1 4.39Å; F158-I176 HydrophobicContact CZ-CD1 4.1Å; F158-F180 HydrophobicContact CE1-CE1 4.16Å; F158-F180 AromaticContact CE1-CZ 3.88Å; F158-F180 HydrophobicContact CE1-CZ 3.88Å; F158-F180 HydrophobicContact CZ-CE1 4.06Å; F158-F180 AromaticContact CZ-CZ 3.68Å; F158-F180 HydrophobicContact CZ-CZ 3.68Å; F158-V202 HydrophobicContact CD1-CG1 3.6Å; F158-V202 HydrophobicContact CD1-CG2 4Å; F158-V202 HydrophobicContact CE1-CG1 3.42Å; F158-V202 VanDerWaalsContact CE1-CG1 3.42Å; F158-I206 HydrophobicContact CE1-CD1 4.33Å
159	I	98.3	Very high	96.9	Very high	19 Å²	19	39.8 Å²	39.8	10%	0.097	20%	0.195	C	C	.	.	H	α-helix	trans	-62	-49.1	172.6	-69.9	173.4	0	0	0	110	Y155 E156 F161 L162 E163 Y198 T201 V202	Y155-I159 WeakPolarHBondContact O-CG1 3.22Å; Y155-I159 PolarHBondContact O-N 2.84Å; E156-I159 PolarHBondContact O-N 2.72Å; I159-F161 VanDerWaalsContact C-N 3.29Å; I159-F161 PolarHBondContact O-N 3.06Å; I159-L162 PolarHBondContact O-N 2.91Å; I159-L162 VanDerWaalsContact O-N 3.14Å; I159-E163 HydrophobicContact CG2-CG 4.15Å; I159-E163 WeakPolarHBondContact O-CB 3.42Å; I159-E163 WeakPolarHBondContact O-CG 3.41Å; I159-E163 PolarHBondContact O-N 2.93Å; I159-Y198 HydrophobicContact CD1-CD1 3.54Å; I159-Y198 HydrophobicContact CD1-CE1 4.09Å; I159-T201 HydrophobicContact CD1-CG2 3.77Å; I159-T201 HydrophobicContact CG1-CG2 4.23Å; I159-T201 HydrophobicContact CG2-CG2 4.31Å; I159-V202 HydrophobicContact CD1-CG2 4.21Å; I159-V202 HydrophobicContact CG1-CG2 3.62Å
160	R	97.6	Very high	96.9	Very high	84 Å²	84	40.2 Å²	40.2	32%	0.317	20%	0.199	S	C	.	.	H	α-helix	trans	-60.1	-39.5	177.3	-60.6	-58.3	177.9	87.9	7.1	112	V97 I100 T101 E156 F157 E163 S164	V97-R160 HydrophobicContact CG1-CG 4.46Å; I100-R160 HydrophobicContact CG2-CB 3.83Å; T101-R160 VanDerWaalsContact CG2-NH1 3.32Å; T101-R160 PolarHBondContact OG1-NH1 3.04Å; E156-R160 HydrophobicContact CG-CG 4.5Å; E156-R160 WeakPolarHBondContact O-CG 3.33Å; E156-R160 PolarHBondContact O-N 3.01Å; E156-R160 IonicContact OE1-CZ 3.08Å; E156-R160 IonicContact OE1-NH2 2.63Å; E156-R160 PolarHBondContact OE1-NH2 3.19Å; F157-R160 PolarHBondContact O-N 3.35Å; R160-E163 PolarHBondContact O-N 2.91Å; R160-S164 PolarHBondContact O-N 3.26Å
161	F	97.5	Very high	96.9	Very high	0 Å²	0	40.5 Å²	40.5	0%	0	20%	0.201	C	C	.	.	H	α-helix	trans	-59.8	-48	173.6	168.9	-110.4	0	0	0	112.2	I100 L107 Y112 V115 F157 F158 I159 F167	I100-F161 HydrophobicContact CD1-CB 3.57Å; I100-F161 HydrophobicContact CD1-CD2 3.97Å; I100-F161 HydrophobicContact CD1-CG 4.27Å; L107-F161 HydrophobicContact CD1-CD2 4.12Å; L107-F161 HydrophobicContact CD1-CE2 4.29Å; L107-F161 HydrophobicContact CD2-CD2 3.79Å; L107-F161 HydrophobicContact CD2-CE2 3.97Å; Y112-F161 HydrophobicContact CD1-CE2 4.09Å; Y112-F161 AromaticContact CD1-CZ 3.56Å; Y112-F161 HydrophobicContact CD1-CZ 3.56Å; Y112-F161 HydrophobicContact CE1-CE2 4.06Å; Y112-F161 AromaticContact CE1-CZ 3.8Å; Y112-F161 HydrophobicContact CE1-CZ 3.8Å; Y112-F161 HydrophobicContact CG-CZ 4.3Å; V115-F161 HydrophobicContact CB-CE2 4.35Å; V115-F161 HydrophobicContact CB-CZ 4.31Å; V115-F161 HydrophobicContact CG1-CB 4.44Å; V115-F161 HydrophobicContact CG1-CD1 3.67Å; V115-F161 HydrophobicContact CG1-CD2 4.04Å; V115-F161 HydrophobicContact CG1-CE1 3.72Å; V115-F161 HydrophobicContact CG1-CE2 4.12Å; V115-F161 HydrophobicContact CG1-CG 3.79Å; V115-F161 HydrophobicContact CG1-CZ 3.95Å; V115-F161 HydrophobicContact CG2-CD2 4.36Å; V115-F161 HydrophobicContact CG2-CE2 4.33Å; F157-F161 WeakPolarHBondContact O-CB 3.39Å; F157-F161 PolarHBondContact O-N 3.4Å; F158-F161 AromaticContact CD2-CD1 3.71Å; F158-F161 HydrophobicContact CD2-CD1 3.71Å; F158-F161 HydrophobicContact CD2-CE1 4.4Å; F158-F161 AromaticContact CE2-CD1 3.71Å; F158-F161 HydrophobicContact CE2-CD1 3.71Å; F158-F161 AromaticContact CE2-CE1 3.98Å; F158-F161 HydrophobicContact CE2-CE1 3.98Å; F158-F161 WeakPolarHBondContact O-CB 3.46Å; F158-F161 PolarHBondContact O-N 3.4Å; I159-F161 VanDerWaalsContact C-N 3.29Å; I159-F161 PolarHBondContact O-N 3.06Å; F161-F167 HydrophobicContact CD1-CD2 4.34Å; F161-F167 HydrophobicContact CD1-CE2 4.05Å; F161-F167 HydrophobicContact CD2-CD2 4.39Å; F161-F167 HydrophobicContact CE1-CD2 4.05Å; F161-F167 AromaticContact CE1-CE2 3.48Å; F161-F167 HydrophobicContact CE1-CE2 3.48Å; F161-F167 VanDerWaalsContact CE1-CE2 3.48Å; F161-F167 HydrophobicContact CE2-CD2 4.07Å; F161-F167 HydrophobicContact CE2-CE2 4.22Å; F161-F167 AromaticContact CZ-CD2 3.92Å; F161-F167 HydrophobicContact CZ-CD2 3.92Å; F161-F167 AromaticContact CZ-CE2 3.59Å; F161-F167 HydrophobicContact CZ-CE2 3.59Å; F161-F167 WeakPolarHBondContact O-CD2 3.27Å
162	L	97.4	Very high	96.9	Very high	0 Å²	0	40.3 Å²	40.3	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-66.4	-38.7	177.8	-69.1	172.8	0	0	0	111.3	F158 I159 F167 I176 V202 R205 I206 K209	F158-L162 HydrophobicContact CD1-CD1 4.11Å; F158-L162 HydrophobicContact CD2-CG 4.4Å; F158-L162 HydrophobicContact CE1-CD1 3.89Å; F158-L162 HydrophobicContact CE2-CD1 4.4Å; F158-L162 HydrophobicContact CE2-CD2 4.29Å; F158-L162 HydrophobicContact CE2-CG 4.2Å; F158-L162 HydrophobicContact CG-CD1 4.47Å; F158-L162 HydrophobicContact CZ-CD1 4.03Å; F158-L162 HydrophobicContact CZ-CD2 4.28Å; F158-L162 HydrophobicContact CZ-CG 4.27Å; F158-L162 VanDerWaalsContact O-CG 3.3Å; F158-L162 WeakPolarHBondContact O-CG 3.5Å; F158-L162 PolarHBondContact O-N 3.45Å; I159-L162 PolarHBondContact O-N 2.91Å; I159-L162 VanDerWaalsContact O-N 3.14Å; L162-F167 HydrophobicContact CD2-CE1 4.46Å; L162-F167 HydrophobicContact CD2-CE2 3.94Å; L162-F167 HydrophobicContact CD2-CZ 3.76Å; L162-I176 HydrophobicContact CD2-CD1 4.29Å; L162-V202 HydrophobicContact CD1-CG1 4.12Å; L162-R205 HydrophobicContact CB-CB 4.32Å; L162-R205 HydrophobicContact CD1-CB 4.18Å; L162-I206 HydrophobicContact CD1-CG1 4.02Å; L162-I206 HydrophobicContact CD2-CG1 4.43Å; L162-K209 WeakPolarHBondContact O-CD 3.48Å; L162-K209 WeakPolarHBondContact O-CE 3.35Å; L162-K209 PolarHBondContact O-NZ 3.44Å
163	E	96.2	Very high	96.8	Very high	79 Å²	79	43.2 Å²	43.2	37%	0.369	21%	0.211	S	C	.	.	H	α-helix	trans	-80.1	-15.3	-177.4	-70.2	-175.2	156.3	0	0	114.4	I159 R160 Q165 R205	I159-E163 HydrophobicContact CG2-CG 4.15Å; I159-E163 WeakPolarHBondContact O-CB 3.42Å; I159-E163 WeakPolarHBondContact O-CG 3.41Å; I159-E163 PolarHBondContact O-N 2.93Å; R160-E163 PolarHBondContact O-N 2.91Å; E163-Q165 PolarHBondContact O-N 3.28Å; E163-R205 HydrophobicContact CG-CG 4.45Å; E163-R205 IonicContact OE1-CZ 3.79Å; E163-R205 IonicContact OE1-NE 2.89Å; E163-R205 PolarHBondContact OE1-NE 3.19Å; E163-R205 IonicContact OE1-NH2 3.27Å; E163-R205 PolarHBondContact OE1-NH2 3.46Å
164	S	95	Very high	96.7	Very high	21 Å²	21	48.9 Å²	48.9	15%	0.147	24%	0.235	C	C	.	.			trans	-52.3	136.8	177.4	178.3	0	0	0	0	111.9	R160 E166 F167	R160-S164 PolarHBondContact O-N 3.26Å; S164-E166 PolarHBondContact O-N 2.65Å; S164-E166 PolarHBondContact OG-N 3.38Å; S164-F167 WeakPolarHBondContact O-CB 3.39Å; S164-F167 PolarHBondContact O-N 2.87Å; S164-F167 VanDerWaalsContact O-N 3.15Å
165	Q	93.2	Very high	96.6	Very high	200 Å²	200	53 Å²	53	94%	0.935	25%	0.251	S	S	*	.	T	Hydrogen-bonded Turn	trans	-66.4	-22.1	175.9	-62.8	-177.7	9.8	0	0	112.1	E163 F167	E163-Q165 PolarHBondContact O-N 3.28Å; Q165-F167 VanDerWaalsContact C-N 3.31Å
166	E	93.5	Very high	96.6	Very high	65 Å²	65	53 Å²	53	30%	0.304	25%	0.251	S	S	.	.	T	Hydrogen-bonded Turn	trans	-86	-4.1	177.5	-59	-173.7	162.6	0	0	112.8	R104 G105 L107 Y112 S164 Q168	R104-E166 WeakPolarHBondContact CA-OE1 3.23Å; G105-E166 WeakPolarHBondContact CA-OE2 3.4Å; G105-E166 PolarHBondContact N-OE1 3.32Å; G105-E166 PolarHBondContact N-OE2 3.38Å; L107-E166 HydrophobicContact CB-CB 4.4Å; L107-E166 HydrophobicContact CD1-CB 4.24Å; Y112-E166 PolarHBondContact OH-O 3.19Å; S164-E166 PolarHBondContact O-N 2.65Å; S164-E166 PolarHBondContact OG-N 3.38Å; E166-Q168 PolarHBondContact O-N 3.46Å
167	F	96	Very high	96.5	Very high	14 Å²	14	54.1 Å²	54.1	6%	0.061	26%	0.259	C	S	.	.			trans	-66.6	124.7	-179.6	-178	-94.6	0	0	0	111.5	L107 Y112 F161 L162 S164 Q165 P169 A172 K209 F210	L107-F167 HydrophobicContact CD1-CB 4.49Å; Y112-F167 HydrophobicContact CD1-CE2 4.48Å; Y112-F167 AromaticContact CE1-CD2 3.94Å; Y112-F167 HydrophobicContact CE1-CD2 3.94Å; Y112-F167 AromaticContact CE1-CE2 3.88Å; Y112-F167 HydrophobicContact CE1-CE2 3.88Å; F161-F167 HydrophobicContact CD1-CD2 4.34Å; F161-F167 HydrophobicContact CD1-CE2 4.05Å; F161-F167 HydrophobicContact CD2-CD2 4.39Å; F161-F167 HydrophobicContact CE1-CD2 4.05Å; F161-F167 AromaticContact CE1-CE2 3.48Å; F161-F167 HydrophobicContact CE1-CE2 3.48Å; F161-F167 VanDerWaalsContact CE1-CE2 3.48Å; F161-F167 HydrophobicContact CE2-CD2 4.07Å; F161-F167 HydrophobicContact CE2-CE2 4.22Å; F161-F167 AromaticContact CZ-CD2 3.92Å; F161-F167 HydrophobicContact CZ-CD2 3.92Å; F161-F167 AromaticContact CZ-CE2 3.59Å; F161-F167 HydrophobicContact CZ-CE2 3.59Å; F161-F167 WeakPolarHBondContact O-CD2 3.27Å; L162-F167 HydrophobicContact CD2-CE1 4.46Å; L162-F167 HydrophobicContact CD2-CE2 3.94Å; L162-F167 HydrophobicContact CD2-CZ 3.76Å; S164-F167 WeakPolarHBondContact O-CB 3.39Å; S164-F167 PolarHBondContact O-N 2.87Å; S164-F167 VanDerWaalsContact O-N 3.15Å; Q165-F167 VanDerWaalsContact C-N 3.31Å; F167-P169 HydrophobicContact CD1-CG 4.1Å; F167-P169 HydrophobicContact CE1-CB 4.36Å; F167-P169 HydrophobicContact CE1-CG 3.94Å; F167-P169 WeakPolarHBondContact O-CD 3.27Å; F167-A172 HydrophobicContact CE1-CB 4.33Å; F167-A172 HydrophobicContact CE2-CB 3.86Å; F167-A172 HydrophobicContact CZ-CB 3.51Å; F167-K209 HydrophobicContact CD1-CD 3.87Å; F167-K209 HydrophobicContact CE1-CB 4.42Å; F167-K209 HydrophobicContact CE1-CD 3.86Å; F167-F210 HydrophobicContact CE1-CE2 4.29Å; F167-F210 HydrophobicContact CE1-CZ 4.06Å; F167-F210 HydrophobicContact CZ-CE2 4.05Å; F167-F210 AromaticContact CZ-CZ 3.71Å; F167-F210 HydrophobicContact CZ-CZ 3.71Å
168	Q	96.4	Very high	96.5	Very high	96 Å²	96	59.1 Å²	59.1	45%	0.449	28%	0.282	S	S	.	.			trans	-111.6	104.3	-178.9	-65.4	-175.6	44	0	0	111	Y112 E166 S170 I171 A172	Y112-Q168 PolarHBondContact OH-N 3.09Å; E166-Q168 PolarHBondContact O-N 3.46Å; Q168-S170 PolarHBondContact O-N 2.87Å; Q168-S170 VanDerWaalsContact O-N 3.13Å; Q168-I171 HydrophobicContact CB-CD1 3.94Å; Q168-I171 HydrophobicContact CB-CG1 4.31Å; Q168-I171 HydrophobicContact CG-CD1 4.41Å; Q168-I171 PolarHBondContact O-N 2.81Å; Q168-I171 VanDerWaalsContact O-N 3.13Å; Q168-A172 PolarHBondContact O-N 3.19Å; Q168-A172 VanDerWaalsContact O-N 3.15Å
169	P	96.2	Very high	96.5	Very high	49 Å²	49	65.7 Å²	65.7	32%	0.318	31%	0.311	S	S	.	.	H	α-helix	trans	-59.1	-27.5	178.8	-24.1	33.1	0	0	0	113.8	F167 I171 K173 K209 F210	F167-P169 HydrophobicContact CD1-CG 4.1Å; F167-P169 HydrophobicContact CE1-CB 4.36Å; F167-P169 HydrophobicContact CE1-CG 3.94Å; F167-P169 WeakPolarHBondContact O-CD 3.27Å; P169-I171 VanDerWaalsContact C-N 3.31Å; P169-I171 PolarHBondContact O-N 3.36Å; P169-K173 WeakPolarHBondContact O-CB 3.21Å; P169-K173 PolarHBondContact O-N 3.33Å; P169-K209 HydrophobicContact CG-CB 4.33Å; P169-F210 HydrophobicContact CB-CD1 4.36Å; P169-F210 HydrophobicContact CB-CE1 4.14Å
170	S	95.8	Very high	96.5	Very high	67 Å²	67	65.1 Å²	65.1	47%	0.469	31%	0.308	S	S	.	.	H	α-helix	trans	-63.9	-32	178.3	52.5	0	0	0	0	113.6	Q168 K173	Q168-S170 PolarHBondContact O-N 2.87Å; Q168-S170 VanDerWaalsContact O-N 3.13Å; S170-K173 VanDerWaalsContact O-CE 3.24Å; S170-K173 WeakPolarHBondContact O-CE 3.29Å; S170-K173 WeakPolarHBondContact O-CG 3.35Å
171	I	96.5	Very high	96.5	Very high	13 Å²	13	61.1 Å²	61.1	7%	0.067	29%	0.292	C	S	.	.	H	α-helix	trans	-85.4	-49.9	175.3	-61.9	164.8	0	0	0	109	E109 Y112 Q168 P169 K173 K174 Y175	E109-I171 HydrophobicContact CG-CD1 3.89Å; Y112-I171 HydrophobicContact CD1-CG2 4.23Å; Y112-I171 HydrophobicContact CD2-CB 4.4Å; Y112-I171 HydrophobicContact CD2-CG2 3.65Å; Y112-I171 HydrophobicContact CE2-CB 4.38Å; Y112-I171 HydrophobicContact CE2-CD1 4.28Å; Y112-I171 HydrophobicContact CE2-CG2 4.08Å; Y112-I171 HydrophobicContact CG-CG2 3.77Å; Q168-I171 HydrophobicContact CB-CD1 3.94Å; Q168-I171 HydrophobicContact CB-CG1 4.31Å; Q168-I171 HydrophobicContact CG-CD1 4.41Å; Q168-I171 PolarHBondContact O-N 2.81Å; Q168-I171 VanDerWaalsContact O-N 3.13Å; P169-I171 VanDerWaalsContact C-N 3.31Å; P169-I171 PolarHBondContact O-N 3.36Å; I171-K173 VanDerWaalsContact C-N 3.25Å; I171-K173 PolarHBondContact O-N 2.92Å; I171-K174 WeakPolarHBondContact O-CB 3.33Å; I171-K174 PolarHBondContact O-N 3.22Å; I171-Y175 HydrophobicContact CG2-CE2 4.44Å
172	A	97.2	Very high	96.5	Very high	0 Å²	0	64.2 Å²	64.2	0%	0	31%	0.309	C	S	.	.	H	α-helix	trans	-60.2	-30.7	-175.1	0	0	0	0	0	113.8	Y112 F167 Q168 K174 Y175 I176 F210	Y112-A172 HydrophobicContact CD1-CB 3.65Å; Y112-A172 HydrophobicContact CE1-CB 3.81Å; F167-A172 HydrophobicContact CE1-CB 4.33Å; F167-A172 HydrophobicContact CE2-CB 3.86Å; F167-A172 HydrophobicContact CZ-CB 3.51Å; Q168-A172 PolarHBondContact O-N 3.19Å; Q168-A172 VanDerWaalsContact O-N 3.15Å; A172-K174 PolarHBondContact O-N 3.44Å; A172-Y175 PolarHBondContact O-N 3.3Å; A172-I176 HydrophobicContact CB-CD1 4.49Å; A172-I176 PolarHBondContact O-N 3.21Å; A172-F210 HydrophobicContact CB-CE1 3.92Å; A172-F210 HydrophobicContact CB-CZ 3.6Å
173	K	96	Very high	96.5	Very high	134 Å²	134	67.3 Å²	67.3	58%	0.583	32%	0.323	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60.3	-17.2	-180	70.9	-178.6	-176.1	176.5	0	114.2	P169 S170 I171 Y175 F210	P169-K173 WeakPolarHBondContact O-CB 3.21Å; P169-K173 PolarHBondContact O-N 3.33Å; S170-K173 VanDerWaalsContact O-CE 3.24Å; S170-K173 WeakPolarHBondContact O-CE 3.29Å; S170-K173 WeakPolarHBondContact O-CG 3.35Å; I171-K173 VanDerWaalsContact C-N 3.25Å; I171-K173 PolarHBondContact O-N 2.92Å; K173-Y175 VanDerWaalsContact C-N 3.25Å; K173-F210 HydrophobicContact CB-CD1 4.18Å; K173-F210 HydrophobicContact CB-CE1 4.04Å
174	K	96.1	Very high	96.6	Very high	137 Å²	137	63.5 Å²	63.5	60%	0.596	31%	0.306	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.8	-20.7	174.8	-62.5	177.7	-175.6	173.9	0	112.3	I171 A172	I171-K174 WeakPolarHBondContact O-CB 3.33Å; I171-K174 PolarHBondContact O-N 3.22Å; A172-K174 PolarHBondContact O-N 3.44Å
175	Y	96.9	Very high	96.8	Very high	85 Å²	85	62.6 Å²	62.6	33%	0.333	30%	0.299	S	S	.	.	T	Hydrogen-bonded Turn	trans	-121	-31.7	-172.1	-49.1	-69.2	0	0	0	112.5	P113 I171 A172 K173 D177	P113-Y175 HydrophobicContact CB-CD1 4.08Å; P113-Y175 HydrophobicContact CB-CE1 3.69Å; P113-Y175 HydrophobicContact CB-CE2 4.4Å; P113-Y175 HydrophobicContact CG-CE1 4.31Å; P113-Y175 HydrophobicContact CG-CE2 4.46Å; I171-Y175 HydrophobicContact CG2-CE2 4.44Å; A172-Y175 PolarHBondContact O-N 3.3Å; K173-Y175 VanDerWaalsContact C-N 3.25Å; Y175-D177 PolarHBondContact O-N 3.19Å
176	I	97.7	Very high	97	Very high	1 Å²	1	58.6 Å²	58.6	1%	0.005	28%	0.28	C	S	.	.	S	Bend	trans	-94.8	85.1	171.5	-57.7	179.1	0	0	0	107.3	V116 F158 L162 A172 F180 I206 F210 L213	V116-I176 HydrophobicContact CG2-CD1 4.41Å; V116-I176 HydrophobicContact CG2-CG1 3.95Å; F158-I176 HydrophobicContact CE2-CD1 4.39Å; F158-I176 HydrophobicContact CZ-CD1 4.1Å; L162-I176 HydrophobicContact CD2-CD1 4.29Å; A172-I176 HydrophobicContact CB-CD1 4.49Å; A172-I176 PolarHBondContact O-N 3.21Å; I176-F180 HydrophobicContact CG2-CD1 3.82Å; I176-F180 HydrophobicContact CG2-CE1 4.3Å; I176-F180 HydrophobicContact CG2-CG 4.34Å; I176-I206 HydrophobicContact CG2-CD1 4.42Å; I176-I206 HydrophobicContact CG2-CG2 4.37Å; I176-F210 HydrophobicContact CB-CE2 4.44Å; I176-F210 HydrophobicContact CB-CZ 4.13Å; I176-F210 HydrophobicContact CD1-CE2 3.99Å; I176-F210 HydrophobicContact CD1-CZ 3.87Å; I176-F210 HydrophobicContact CG1-CZ 4.49Å; I176-F210 HydrophobicContact CG2-CE2 4.18Å; I176-F210 HydrophobicContact CG2-CZ 4.35Å; I176-L213 HydrophobicContact CG2-CD1 4.18Å
177	D	96.9	Very high	97.2	Very high	73 Å²	73	55.6 Å²	55.6	39%	0.39	27%	0.266	S	S	.	.			trans	-104.3	-171.4	-178.5	70.9	2	0	0	0	112	Y175 K179 F180 V181	Y175-D177 PolarHBondContact O-N 3.19Å; D177-K179 VanDerWaalsContact C-N 3.26Å; D177-K179 PolarHBondContact O-N 2.76Å; D177-K179 WeakPolarHBondContact OD1-CA 2.82Å; D177-K179 WeakPolarHBondContact OD1-CB 3.38Å; D177-K179 PolarHBondContact OD1-N 2.77Å; D177-F180 PolarHBondContact O-N 3.13Å; D177-F180 PolarHBondContact OD1-N 3.15Å; D177-V181 WeakPolarHBondContact O-CG2 3.44Å; D177-V181 PolarHBondContact O-N 2.93Å; D177-V181 VanDerWaalsContact O-N 3.12Å
178	Q	98.1	Very high	97.2	Very high	105 Å²	105	55 Å²	55	49%	0.491	26%	0.263	S	S	.	.	H	α-helix	trans	-63.7	-31.5	177.4	-69.4	-175	3	0	0	112.9	V181 L182 L213 F216	Q178-V181 PolarHBondContact O-N 2.63Å; Q178-L182 WeakPolarHBondContact O-CB 3.44Å; Q178-L182 PolarHBondContact O-N 2.84Å; Q178-L213 HydrophobicContact CG-CD2 4.03Å; Q178-F216 HydrophobicContact CB-CD1 4.03Å; Q178-F216 HydrophobicContact CB-CD2 4.19Å; Q178-F216 HydrophobicContact CB-CE1 3.75Å; Q178-F216 HydrophobicContact CB-CE2 3.91Å; Q178-F216 HydrophobicContact CB-CG 4.24Å; Q178-F216 HydrophobicContact CB-CZ 3.69Å; Q178-F216 VanDerWaalsContact CD-CD2 3.42Å; Q178-F216 HydrophobicContact CG-CB 4.27Å; Q178-F216 HydrophobicContact CG-CD1 3.88Å; Q178-F216 HydrophobicContact CG-CD2 3.81Å; Q178-F216 HydrophobicContact CG-CE1 4.14Å; Q178-F216 HydrophobicContact CG-CE2 4.06Å; Q178-F216 HydrophobicContact CG-CG 3.71Å; Q178-F216 HydrophobicContact CG-CZ 4.22Å; Q178-F216 VanDerWaalsContact O-CE1 3.23Å; Q178-F216 WeakPolarHBondContact O-CE1 3.5Å
179	K	97.5	Very high	97.2	Very high	138 Å²	138	52.9 Å²	52.9	60%	0.6	26%	0.256	S	S	*	.	H	α-helix	trans	-69.3	-44.2	178.2	-179.1	-175.7	176	-175.9	0	110.4	D177 V181 L182 Q183	D177-K179 VanDerWaalsContact C-N 3.26Å; D177-K179 PolarHBondContact O-N 2.76Å; D177-K179 WeakPolarHBondContact OD1-CA 2.82Å; D177-K179 WeakPolarHBondContact OD1-CB 3.38Å; D177-K179 PolarHBondContact OD1-N 2.77Å; K179-V181 VanDerWaalsContact C-N 3.31Å; K179-V181 PolarHBondContact O-N 2.65Å; K179-L182 PolarHBondContact O-N 3.45Å; K179-Q183 WeakPolarHBondContact O-CG 3.44Å; K179-Q183 PolarHBondContact O-N 3.39Å
180	F	98.2	Very high	97.1	Very high	6 Å²	6	50.9 Å²	50.9	3%	0.026	24%	0.243	C	C	.	.	H	α-helix	trans	-56.1	-47.5	173.6	-175.2	-81.3	0	0	0	111	V116 V119 F124 F158 I176 D177 L182 Q183 L184 I206	V116-F180 HydrophobicContact CG1-CD2 3.95Å; V116-F180 HydrophobicContact CG1-CE2 3.88Å; V119-F180 HydrophobicContact CG1-CZ 4.43Å; F124-F180 AromaticContact CE2-CD2 3.53Å; F124-F180 HydrophobicContact CE2-CD2 3.53Å; F124-F180 AromaticContact CE2-CE2 3.56Å; F124-F180 HydrophobicContact CE2-CE2 3.56Å; F124-F180 HydrophobicContact CE2-CG 4.21Å; F124-F180 HydrophobicContact CE2-CZ 4.26Å; F124-F180 HydrophobicContact CZ-CD1 4.16Å; F124-F180 AromaticContact CZ-CD2 3.61Å; F124-F180 HydrophobicContact CZ-CD2 3.61Å; F124-F180 HydrophobicContact CZ-CE1 4.05Å; F124-F180 AromaticContact CZ-CE2 3.48Å; F124-F180 HydrophobicContact CZ-CE2 3.48Å; F124-F180 VanDerWaalsContact CZ-CE2 3.48Å; F124-F180 AromaticContact CZ-CG 3.95Å; F124-F180 HydrophobicContact CZ-CG 3.95Å; F124-F180 AromaticContact CZ-CZ 3.72Å; F124-F180 HydrophobicContact CZ-CZ 3.72Å; F158-F180 HydrophobicContact CE1-CE1 4.16Å; F158-F180 AromaticContact CE1-CZ 3.88Å; F158-F180 HydrophobicContact CE1-CZ 3.88Å; F158-F180 HydrophobicContact CZ-CE1 4.06Å; F158-F180 AromaticContact CZ-CZ 3.68Å; F158-F180 HydrophobicContact CZ-CZ 3.68Å; I176-F180 HydrophobicContact CG2-CD1 3.82Å; I176-F180 HydrophobicContact CG2-CE1 4.3Å; I176-F180 HydrophobicContact CG2-CG 4.34Å; D177-F180 PolarHBondContact O-N 3.13Å; D177-F180 PolarHBondContact OD1-N 3.15Å; F180-L182 PolarHBondContact O-N 3.13Å; F180-Q183 PolarHBondContact O-N 3.35Å; F180-L184 HydrophobicContact CE1-CD2 4.47Å; F180-L184 WeakPolarHBondContact O-CB 3.45Å; F180-L184 PolarHBondContact O-N 3.43Å; F180-I206 HydrophobicContact CE1-CD1 4.01Å
181	V	98.4	Very high	96.9	Very high	0 Å²	0	49 Å²	49	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-63.1	-40.5	178.4	169.9	0	0	0	0	112.2	D177 Q178 K179 L184 L185 I206 L213 F216 I217	D177-V181 WeakPolarHBondContact O-CG2 3.44Å; D177-V181 PolarHBondContact O-N 2.93Å; D177-V181 VanDerWaalsContact O-N 3.12Å; Q178-V181 PolarHBondContact O-N 2.63Å; K179-V181 VanDerWaalsContact C-N 3.31Å; K179-V181 PolarHBondContact O-N 2.65Å; V181-L184 PolarHBondContact O-N 2.89Å; V181-L185 HydrophobicContact CG1-CD1 3.96Å; V181-L185 HydrophobicContact CG1-CG 4.44Å; V181-L185 WeakPolarHBondContact O-CB 3.26Å; V181-L185 WeakPolarHBondContact O-CG 3.28Å; V181-L185 PolarHBondContact O-N 3.36Å; V181-I206 HydrophobicContact CG2-CG2 4.31Å; V181-L213 HydrophobicContact CG2-CD1 3.92Å; V181-F216 HydrophobicContact CB-CD1 4.31Å; V181-F216 HydrophobicContact CB-CE1 4.13Å; V181-F216 HydrophobicContact CG1-CD1 3.95Å; V181-F216 HydrophobicContact CG1-CE1 3.95Å; V181-I217 HydrophobicContact CG1-CD1 4.45Å; V181-I217 HydrophobicContact CG1-CG1 3.59Å
182	L	97.7	Very high	96.7	Very high	65 Å²	65	48.4 Å²	48.4	34%	0.34	22%	0.224	S	C	.	.	H	α-helix	trans	-62.5	-48.6	178.3	-178.4	64.4	0	0	0	111.2	Q178 K179 F180 L184 L185 E186	Q178-L182 WeakPolarHBondContact O-CB 3.44Å; Q178-L182 PolarHBondContact O-N 2.84Å; K179-L182 PolarHBondContact O-N 3.45Å; F180-L182 PolarHBondContact O-N 3.13Å; L182-L184 VanDerWaalsContact C-N 3.29Å; L182-L184 PolarHBondContact O-N 2.78Å; L182-L185 PolarHBondContact O-N 3.38Å; L182-L185 VanDerWaalsContact O-N 3.16Å; L182-E186 WeakPolarHBondContact O-CG 3.24Å; L182-E186 PolarHBondContact O-N 3.01Å
183	Q	97.7	Very high	96.6	Very high	65 Å²	65	50.9 Å²	50.9	30%	0.304	24%	0.24	S	C	.	.	H	α-helix	trans	-63.1	-36.1	177.2	-68.1	-175.9	-31	0	0	112	F124 K179 F180 E186 L187	F124-Q183 HydrophobicContact CD1-CB 3.62Å; F124-Q183 HydrophobicContact CD2-CB 4.15Å; F124-Q183 HydrophobicContact CE1-CB 3.76Å; F124-Q183 HydrophobicContact CE2-CB 4.24Å; F124-Q183 HydrophobicContact CG-CB 3.88Å; F124-Q183 HydrophobicContact CZ-CB 4.06Å; K179-Q183 WeakPolarHBondContact O-CG 3.44Å; K179-Q183 PolarHBondContact O-N 3.39Å; F180-Q183 PolarHBondContact O-N 3.35Å; Q183-E186 PolarHBondContact O-N 3.34Å; Q183-L187 WeakPolarHBondContact O-CG 3.44Å
184	L	98.4	Very high	96.6	Very high	0 Å²	0	48.7 Å²	48.7	0%	0	23%	0.228	C	C	.	.	H	α-helix	trans	-64.7	-40.8	174.2	-172.7	73.4	0	0	0	112.1	I123 F124 F180 V181 L182 L187 L199 V202 L203 I206	I123-L184 HydrophobicContact CD1-CD1 3.93Å; F124-L184 HydrophobicContact CE1-CB 4.03Å; F124-L184 HydrophobicContact CE1-CD1 4.3Å; F124-L184 HydrophobicContact CZ-CB 4.47Å; F180-L184 HydrophobicContact CE1-CD2 4.47Å; F180-L184 WeakPolarHBondContact O-CB 3.45Å; F180-L184 PolarHBondContact O-N 3.43Å; V181-L184 PolarHBondContact O-N 2.89Å; L182-L184 VanDerWaalsContact C-N 3.29Å; L182-L184 PolarHBondContact O-N 2.78Å; L184-L187 PolarHBondContact O-N 3.31Å; L184-L199 HydrophobicContact CD1-CD2 3.45Å; L184-L199 VanDerWaalsContact CD1-CD2 3.45Å; L184-L199 HydrophobicContact CG-CD2 4.15Å; L184-V202 HydrophobicContact CD1-CG1 4.22Å; L184-V202 HydrophobicContact CD2-CG1 3.89Å; L184-L203 HydrophobicContact CD2-CB 4.37Å; L184-L203 HydrophobicContact CD2-CD1 4.23Å; L184-I206 HydrophobicContact CD2-CD1 3.72Å
185	L	98.3	Very high	96.7	Very high	2 Å²	2	42.2 Å²	42.2	1%	0.01	20%	0.199	C	C	.	.	H	α-helix	trans	-67.7	-34.1	178	-78.6	169.5	0	0	0	112.6	V181 L182 L187 F188 L203 Q220 I221 I224 L241	V181-L185 HydrophobicContact CG1-CD1 3.96Å; V181-L185 HydrophobicContact CG1-CG 4.44Å; V181-L185 WeakPolarHBondContact O-CB 3.26Å; V181-L185 WeakPolarHBondContact O-CG 3.28Å; V181-L185 PolarHBondContact O-N 3.36Å; L182-L185 PolarHBondContact O-N 3.38Å; L182-L185 VanDerWaalsContact O-N 3.16Å; L185-L187 PolarHBondContact O-N 2.85Å; L185-F188 HydrophobicContact CD2-CD2 4.37Å; L185-F188 HydrophobicContact CD2-CE2 4.4Å; L185-F188 WeakPolarHBondContact O-CB 3.32Å; L185-F188 PolarHBondContact O-N 3.34Å; L185-L203 HydrophobicContact CD2-CD1 4.39Å; L185-L203 HydrophobicContact CD2-CD2 3.54Å; L185-Q220 HydrophobicContact CD1-CB 3.45Å; L185-Q220 VanDerWaalsContact CD1-CB 3.45Å; L185-Q220 HydrophobicContact CD1-CG 4.23Å; L185-I221 HydrophobicContact CD2-CG1 4.06Å; L185-I224 HydrophobicContact CB-CD1 4.16Å; L185-I224 HydrophobicContact CD2-CD1 4.36Å; L185-L241 HydrophobicContact CD2-CD2 4.04Å
186	E	96.9	Very high	96.7	Very high	116 Å²	116	39.8 Å²	39.8	54%	0.542	19%	0.19	S	C	.	.	H	α-helix	trans	-61.2	-30	174.7	-72.2	170.9	-176.1	0	0	112.3	L182 Q183 F188 D189	L182-E186 WeakPolarHBondContact O-CG 3.24Å; L182-E186 PolarHBondContact O-N 3.01Å; Q183-E186 PolarHBondContact O-N 3.34Å; E186-F188 VanDerWaalsContact C-N 3.27Å; E186-F188 PolarHBondContact O-N 3.14Å; E186-D189 PolarHBondContact O-N 2.94Å
187	L	97.8	Very high	96.7	Very high	2 Å²	2	43.3 Å²	43.3	1%	0.01	21%	0.209	C	C	.	.	G	3₁₀ helix	trans	-72.5	-16.4	178.6	-60.3	177.6	0	0	0	113.9	I123 F124 L127 Q183 L184 L185 D189 S190 L199	I123-L187 HydrophobicContact CB-CD1 4Å; I123-L187 HydrophobicContact CD1-CD1 4.18Å; I123-L187 HydrophobicContact CG1-CD1 3.98Å; I123-L187 WeakPolarHBondContact O-CD1 3.39Å; I123-L187 WeakPolarHBondContact O-CD2 3.42Å; F124-L187 HydrophobicContact CD1-CD1 3.87Å; F124-L187 HydrophobicContact CE1-CD1 4.24Å; L127-L187 HydrophobicContact CD2-CD2 4.27Å; Q183-L187 WeakPolarHBondContact O-CG 3.44Å; L184-L187 PolarHBondContact O-N 3.31Å; L185-L187 PolarHBondContact O-N 2.85Å; L187-D189 PolarHBondContact O-N 2.82Å; L187-D189 VanDerWaalsContact O-N 3.14Å; L187-S190 VanDerWaalsContact O-CB 3.28Å; L187-S190 WeakPolarHBondContact O-CB 3.42Å; L187-S190 PolarHBondContact O-N 3.43Å; L187-L199 VanDerWaalsContact C-CD1 3.43Å; L187-L199 HydrophobicContact CB-CD1 3.57Å; L187-L199 HydrophobicContact CB-CD2 3.94Å; L187-L199 HydrophobicContact CB-CG 4.42Å; L187-L199 HydrophobicContact CD1-CD2 4.09Å; L187-L199 VanDerWaalsContact O-CD1 3.24Å; L187-L199 WeakPolarHBondContact O-CD1 3.5Å
188	F	97.8	Very high	96.8	Very high	0 Å²	0	42.2 Å²	42.2	0%	0	20%	0.199	C	C	.	.	G	3₁₀ helix	trans	-64.5	-15.5	176.8	-86.3	-100	0	0	0	112.7	L185 E186 S190 R196 L199 K200 L203 F235 G237 E240 L241 I244	L185-F188 HydrophobicContact CD2-CD2 4.37Å; L185-F188 HydrophobicContact CD2-CE2 4.4Å; L185-F188 WeakPolarHBondContact O-CB 3.32Å; L185-F188 PolarHBondContact O-N 3.34Å; E186-F188 VanDerWaalsContact C-N 3.27Å; E186-F188 PolarHBondContact O-N 3.14Å; F188-S190 PolarHBondContact O-N 3.47Å; F188-R196 VanDerWaalsContact O-CD 3.28Å; F188-R196 WeakPolarHBondContact O-CD 3.36Å; F188-L199 HydrophobicContact CD2-CB 4.12Å; F188-L199 HydrophobicContact CD2-CD1 4.33Å; F188-L199 HydrophobicContact CE1-CB 4.13Å; F188-L199 HydrophobicContact CE2-CB 3.72Å; F188-L199 VanDerWaalsContact CZ-C 3.44Å; F188-L199 HydrophobicContact CZ-CB 3.74Å; F188-L199 WeakPolarHBondContact CZ-O 3.39Å; F188-K200 HydrophobicContact CE1-CB 4.41Å; F188-L203 HydrophobicContact CE2-CB 4.07Å; F188-L203 HydrophobicContact CE2-CD2 3.66Å; F188-L203 HydrophobicContact CE2-CG 4.45Å; F188-L203 HydrophobicContact CZ-CB 3.89Å; F188-L203 HydrophobicContact CZ-CD2 3.63Å; F188-L203 HydrophobicContact CZ-CG 4.41Å; F188-F235 HydrophobicContact CB-CE1 4.02Å; F188-F235 HydrophobicContact CB-CZ 3.67Å; F188-G237 VanDerWaalsContact O-CA 3.23Å; F188-G237 WeakPolarHBondContact O-CA 3.36Å; F188-G237 PolarHBondContact O-N 2.9Å; F188-G237 VanDerWaalsContact O-N 3.13Å; F188-E240 HydrophobicContact CD1-CB 4.22Å; F188-E240 HydrophobicContact CE1-CB 4.01Å; F188-L241 HydrophobicContact CD1-CD2 3.72Å; F188-L241 HydrophobicContact CD1-CG 3.93Å; F188-L241 HydrophobicContact CD2-CD2 4.31Å; F188-L241 HydrophobicContact CE1-CD2 3.71Å; F188-L241 HydrophobicContact CE1-CG 4.27Å; F188-L241 HydrophobicContact CE2-CD2 4.29Å; F188-L241 HydrophobicContact CG-CD2 4.02Å; F188-L241 HydrophobicContact CG-CG 4.36Å; F188-L241 HydrophobicContact CZ-CD2 3.99Å; F188-I244 HydrophobicContact CE1-CD1 4.12Å; F188-I244 HydrophobicContact CZ-CD1 3.96Å
189	D	95.5	Very high	96.8	Very high	53 Å²	53	37.2 Å²	37.2	28%	0.283	18%	0.176	S	C	.	.	G	3₁₀ helix	trans	-79.5	6.1	173.3	-151.3	22	0	0	0	113.3	L127 E186 L187 E191 F235 N236	L127-D189 VanDerWaalsContact CD1-C 3.42Å; L127-D189 HydrophobicContact CD1-CB 3.84Å; E186-D189 PolarHBondContact O-N 2.94Å; L187-D189 PolarHBondContact O-N 2.82Å; L187-D189 VanDerWaalsContact O-N 3.14Å; D189-E191 PolarHBondContact O-N 2.86Å; D189-F235 HydrophobicContact CB-CD2 4Å; D189-F235 HydrophobicContact CB-CE2 3.74Å; D189-F235 HydrophobicContact CB-CZ 4.44Å; D189-F235 VanDerWaalsContact OD1-CA 3.29Å; D189-F235 WeakPolarHBondContact OD1-CA 3.23Å; D189-N236 PolarHBondContact O-ND2 3.36Å; D189-N236 PolarHBondContact OD1-N 3.46Å
190	S	93.7	Very high	96.9	Very high	7 Å²	7	32 Å²	32	5%	0.049	15%	0.153	C	C	.	.			trans	-60.2	133.1	175.2	-176.3	0	0	0	0	110.8	L127 L187 F188 D192 E195 R196	L127-S190 VanDerWaalsContact CD1-N 3.33Å; L187-S190 VanDerWaalsContact O-CB 3.28Å; L187-S190 WeakPolarHBondContact O-CB 3.42Å; L187-S190 PolarHBondContact O-N 3.43Å; F188-S190 PolarHBondContact O-N 3.47Å; S190-D192 PolarHBondContact O-N 2.89Å; S190-D192 PolarHBondContact OG-N 3.44Å; S190-E195 WeakPolarHBondContact CB-OE2 3.33Å; S190-E195 PolarHBondContact OG-OE2 2.95Å; S190-R196 VanDerWaalsContact O-CD 3.26Å; S190-R196 WeakPolarHBondContact O-CD 3.36Å; S190-R196 WeakPolarHBondContact O-CG 3.32Å; S190-R196 PolarHBondContact O-NH1 3.36Å
191	E	91.4	Very high	96.9	Very high	28 Å²	28	33.5 Å²	33.5	13%	0.131	16%	0.163	C	C	.	.	S	Bend	trans	-67.4	-23.7	174	-71.3	-172.6	-171.8	0	0	112	S130 P142 T143 D189 P193 R196	S130-E191 WeakPolarHBondContact CB-OE1 3.38Å; P142-E191 WeakPolarHBondContact CB-O 3.39Å; T143-E191 WeakPolarHBondContact CB-OE2 3.3Å; T143-E191 PolarHBondContact N-OE2 3.15Å; T143-E191 PolarHBondContact OG1-OE2 2.89Å; D189-E191 PolarHBondContact O-N 2.86Å; E191-P193 WeakPolarHBondContact O-CD 3.34Å; E191-R196 PolarHBondContact O-NH1 2.97Å
192	D	93.3	Very high	96.9	Very high	0 Å²	0	33.5 Å²	33.5	0%	0	16%	0.163	C	C	.	.			trans	-75.9	108.8	-178.7	-165.5	-32.2	0	0	0	111.1	E145 S190 R194 E195 R196	E145-D192 PolarHBondContact N-OD2 2.88Å; S190-D192 PolarHBondContact O-N 2.89Å; S190-D192 PolarHBondContact OG-N 3.44Å; D192-R194 PolarHBondContact O-N 2.83Å; D192-R194 VanDerWaalsContact O-N 3.12Å; D192-R194 WeakPolarHBondContact OD1-CB 3.41Å; D192-R194 VanDerWaalsContact OD1-CG 3.32Å; D192-R194 WeakPolarHBondContact OD1-CG 3.36Å; D192-R194 IonicContact OD1-CZ 2.7Å; D192-R194 PolarHBondContact OD1-N 2.99Å; D192-R194 IonicContact OD1-NE 2.77Å; D192-R194 PolarHBondContact OD1-NE 3.33Å; D192-R194 IonicContact OD1-NH2 2.67Å; D192-R194 IonicContact OD2-CZ 3.35Å; D192-R194 IonicContact OD2-NE 3.59Å; D192-R194 PolarHBondContact OD2-NE 2.94Å; D192-R194 IonicContact OD2-NH2 3.94Å; D192-R194 PolarHBondContact OD2-NH2 3.29Å; D192-E195 HydrophobicContact CB-CB 4.2Å; D192-E195 PolarHBondContact O-N 3.47Å; D192-E195 VanDerWaalsContact O-N 3.08Å; D192-R196 PolarHBondContact O-N 3.43Å
193	P	94.1	Very high	97	Very high	52 Å²	52	30.4 Å²	30.4	34%	0.338	15%	0.147	S	C	.	.	H	α-helix	trans	-61.6	-25.3	-178.4	25.6	-34.4	0	0	0	112.7	E191 R196 D197	E191-P193 WeakPolarHBondContact O-CD 3.34Å; P193-R196 PolarHBondContact O-N 3.36Å; P193-D197 PolarHBondContact O-N 2.89Å
194	R	96.7	Very high	97	Very high	88 Å²	88	30 Å²	30	33%	0.332	15%	0.145	S	C	.	.	H	α-helix	trans	-67.5	-43.5	178.1	-51.2	171.1	-66.4	178.4	6	109.9	W148 D192 D197 Y198	W148-R194 VanDerWaalsContact CD1-CZ 3.49Å; W148-R194 VanDerWaalsContact CD1-NH1 3.27Å; W148-R194 VanDerWaalsContact CH2-C 3.45Å; W148-R194 HydrophobicContact CH2-CB 3.61Å; W148-R194 HydrophobicContact CZ2-CB 3.34Å; W148-R194 HydrophobicContact CZ2-CG 4.41Å; W148-R194 HydrophobicContact CZ3-CB 4.32Å; D192-R194 PolarHBondContact O-N 2.83Å; D192-R194 VanDerWaalsContact O-N 3.12Å; D192-R194 WeakPolarHBondContact OD1-CB 3.41Å; D192-R194 VanDerWaalsContact OD1-CG 3.32Å; D192-R194 WeakPolarHBondContact OD1-CG 3.36Å; D192-R194 IonicContact OD1-CZ 2.7Å; D192-R194 PolarHBondContact OD1-N 2.99Å; D192-R194 IonicContact OD1-NE 2.77Å; D192-R194 PolarHBondContact OD1-NE 3.33Å; D192-R194 IonicContact OD1-NH2 2.67Å; D192-R194 IonicContact OD2-CZ 3.35Å; D192-R194 IonicContact OD2-NE 3.59Å; D192-R194 PolarHBondContact OD2-NE 2.94Å; D192-R194 IonicContact OD2-NH2 3.94Å; D192-R194 PolarHBondContact OD2-NH2 3.29Å; R194-D197 PolarHBondContact O-N 3.31Å; R194-Y198 WeakPolarHBondContact O-CD2 3.38Å; R194-Y198 PolarHBondContact O-N 3Å
195	E	97.6	Very high	97	Very high	0 Å²	0	33.9 Å²	33.9	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-62.5	-44.9	176.9	-172	169.7	-163.6	0	0	110.8	R125 W148 Y155 S190 D192 D197 Y198 L199	R125-E195 IonicContact CZ-OE1 2.65Å; R125-E195 IonicContact CZ-OE2 3.98Å; R125-E195 IonicContact NH1-OE1 2.94Å; R125-E195 PolarHBondContact NH1-OE1 2.89Å; R125-E195 IonicContact NH1-OE2 3.8Å; R125-E195 IonicContact NH2-OE1 3.9Å; R125-E195 PolarHBondContact NH2-OE1 2.92Å; R125-E195 VanDerWaalsContact NH2-OE1 3.09Å; R125-E195 IonicContact NH2-OE2 3.1Å; R125-E195 PolarHBondContact NH2-OE2 3Å; W148-E195 HydrophobicContact CH2-CB 4.34Å; W148-E195 HydrophobicContact CZ3-CB 3.75Å; W148-E195 HydrophobicContact CZ3-CG 4.35Å; Y155-E195 HydrophobicContact CE2-CG 3.83Å; Y155-E195 WeakPolarHBondContact OH-CG 3.41Å; Y155-E195 PolarHBondContact OH-OE1 3.04Å; S190-E195 WeakPolarHBondContact CB-OE2 3.33Å; S190-E195 PolarHBondContact OG-OE2 2.95Å; D192-E195 HydrophobicContact CB-CB 4.2Å; D192-E195 PolarHBondContact O-N 3.47Å; D192-E195 VanDerWaalsContact O-N 3.08Å; E195-D197 VanDerWaalsContact C-N 3.34Å; E195-D197 PolarHBondContact O-N 3.12Å; E195-Y198 PolarHBondContact O-N 3.47Å; E195-L199 HydrophobicContact CG-CD1 3.96Å; E195-L199 HydrophobicContact CG-CG 4.36Å; E195-L199 WeakPolarHBondContact O-CB 3.46Å; E195-L199 VanDerWaalsContact O-CG 3.27Å; E195-L199 WeakPolarHBondContact O-CG 3.45Å; E195-L199 PolarHBondContact O-N 2.86Å
196	R	97.4	Very high	97	Very high	34 Å²	34	33.8 Å²	33.8	13%	0.128	16%	0.159	C	C	.	.	H	α-helix	trans	-60.7	-39.7	178.3	-61.3	-162.3	-57.3	-86.3	2.6	112.9	F188 S190 E191 D192 P193 L199 K200 E240	F188-R196 VanDerWaalsContact O-CD 3.28Å; F188-R196 WeakPolarHBondContact O-CD 3.36Å; S190-R196 VanDerWaalsContact O-CD 3.26Å; S190-R196 WeakPolarHBondContact O-CD 3.36Å; S190-R196 WeakPolarHBondContact O-CG 3.32Å; S190-R196 PolarHBondContact O-NH1 3.36Å; E191-R196 PolarHBondContact O-NH1 2.97Å; D192-R196 PolarHBondContact O-N 3.43Å; P193-R196 PolarHBondContact O-N 3.36Å; R196-L199 PolarHBondContact O-N 3.33Å; R196-K200 WeakPolarHBondContact O-CB 3.24Å; R196-K200 PolarHBondContact O-N 2.93Å; R196-E240 HydrophobicContact CB-CG 4Å; R196-E240 WeakPolarHBondContact CB-OE1 3.44Å; R196-E240 IonicContact CZ-OE1 3.27Å; R196-E240 IonicContact NE-OE1 3.83Å; R196-E240 PolarHBondContact NE-OE1 3.01Å; R196-E240 IonicContact NE-OE2 2.95Å; R196-E240 IonicContact NH2-OE1 2.71Å
197	D	98	Very high	97	Very high	76 Å²	76	29.1 Å²	29.1	41%	0.406	14%	0.136	S	C	.	.	H	α-helix	trans	-66.8	-38.8	177.9	-169.4	62.9	0	0	0	113	P193 R194 E195 K200 T201	P193-D197 PolarHBondContact O-N 2.89Å; R194-D197 PolarHBondContact O-N 3.31Å; E195-D197 VanDerWaalsContact C-N 3.34Å; E195-D197 PolarHBondContact O-N 3.12Å; D197-K200 WeakPolarHBondContact O-CB 3.37Å; D197-K200 PolarHBondContact O-N 3.33Å; D197-K200 VanDerWaalsContact OD1-CE 3.27Å; D197-K200 WeakPolarHBondContact OD1-CE 3.36Å; D197-K200 IonicContact OD1-NZ 2.72Å; D197-K200 PolarHBondContact OD1-NZ 2.91Å; D197-T201 PolarHBondContact O-N 3.2Å; D197-T201 PolarHBondContact O-OG1 2.99Å
198	Y	98.5	Very high	97	Very high	50 Å²	50	30.9 Å²	30.9	20%	0.196	16%	0.156	C	C	.	.	H	α-helix	trans	-65.7	-46	171.6	-86.1	-81.7	0	0	0	111.7	W148 Q152 Y155 E156 I159 R194 E195 K200 T201 V202	W148-Y198 AromaticContact CH2-CD2 3.71Å; W148-Y198 HydrophobicContact CH2-CD2 3.71Å; W148-Y198 HydrophobicContact CH2-CE2 4.07Å; W148-Y198 AromaticContact CZ2-CD2 3.98Å; W148-Y198 HydrophobicContact CZ2-CD2 3.98Å; W148-Y198 AromaticContact CZ2-CE2 3.86Å; W148-Y198 HydrophobicContact CZ2-CE2 3.86Å; Q152-Y198 HydrophobicContact CG-CE2 4.19Å; Y155-Y198 HydrophobicContact CD2-CG 4.46Å; Y155-Y198 HydrophobicContact CG-CD1 4.28Å; Y155-Y198 HydrophobicContact CG-CG 4.09Å; E156-Y198 HydrophobicContact CB-CE1 4.27Å; I159-Y198 HydrophobicContact CD1-CD1 3.54Å; I159-Y198 HydrophobicContact CD1-CE1 4.09Å; R194-Y198 WeakPolarHBondContact O-CD2 3.38Å; R194-Y198 PolarHBondContact O-N 3Å; E195-Y198 PolarHBondContact O-N 3.47Å; Y198-K200 VanDerWaalsContact C-N 3.26Å; Y198-K200 PolarHBondContact O-N 3.08Å; Y198-T201 PolarHBondContact O-N 3.29Å; Y198-V202 WeakPolarHBondContact O-CG2 3.39Å; Y198-V202 PolarHBondContact O-N 3.43Å
199	L	98.6	Very high	96.9	Very high	0 Å²	0	34.1 Å²	34.1	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-57.2	-41.2	175.7	-74	168.7	0	0	0	111.7	Y155 L184 L187 F188 E195 R196 T201 V202 L203	Y155-L199 HydrophobicContact CE1-CD2 3.77Å; Y155-L199 HydrophobicContact CE1-CG 4.14Å; L184-L199 HydrophobicContact CD1-CD2 3.45Å; L184-L199 VanDerWaalsContact CD1-CD2 3.45Å; L184-L199 HydrophobicContact CG-CD2 4.15Å; L187-L199 VanDerWaalsContact C-CD1 3.43Å; L187-L199 HydrophobicContact CB-CD1 3.57Å; L187-L199 HydrophobicContact CB-CD2 3.94Å; L187-L199 HydrophobicContact CB-CG 4.42Å; L187-L199 HydrophobicContact CD1-CD2 4.09Å; L187-L199 VanDerWaalsContact O-CD1 3.24Å; L187-L199 WeakPolarHBondContact O-CD1 3.5Å; F188-L199 HydrophobicContact CD2-CB 4.12Å; F188-L199 HydrophobicContact CD2-CD1 4.33Å; F188-L199 HydrophobicContact CE1-CB 4.13Å; F188-L199 HydrophobicContact CE2-CB 3.72Å; F188-L199 VanDerWaalsContact CZ-C 3.44Å; F188-L199 HydrophobicContact CZ-CB 3.74Å; F188-L199 WeakPolarHBondContact CZ-O 3.39Å; E195-L199 HydrophobicContact CG-CD1 3.96Å; E195-L199 HydrophobicContact CG-CG 4.36Å; E195-L199 WeakPolarHBondContact O-CB 3.46Å; E195-L199 VanDerWaalsContact O-CG 3.27Å; E195-L199 WeakPolarHBondContact O-CG 3.45Å; E195-L199 PolarHBondContact O-N 2.86Å; R196-L199 PolarHBondContact O-N 3.33Å; L199-T201 VanDerWaalsContact C-N 3.34Å; L199-T201 PolarHBondContact O-N 2.87Å; L199-V202 PolarHBondContact O-N 3.46Å; L199-L203 VanDerWaalsContact O-CB 3.32Å; L199-L203 WeakPolarHBondContact O-CB 3.08Å; L199-L203 PolarHBondContact O-N 2.95Å
200	K	98.6	Very high	97	Very high	28 Å²	28	32 Å²	32	12%	0.122	16%	0.158	C	C	.	.	H	α-helix	trans	-54.7	-50.7	176	-172.9	-174.4	75.7	-172.7	0	111.3	F188 R196 D197 Y198 H204 E240 E243 I244	F188-K200 HydrophobicContact CE1-CB 4.41Å; R196-K200 WeakPolarHBondContact O-CB 3.24Å; R196-K200 PolarHBondContact O-N 2.93Å; D197-K200 WeakPolarHBondContact O-CB 3.37Å; D197-K200 PolarHBondContact O-N 3.33Å; D197-K200 VanDerWaalsContact OD1-CE 3.27Å; D197-K200 WeakPolarHBondContact OD1-CE 3.36Å; D197-K200 IonicContact OD1-NZ 2.72Å; D197-K200 PolarHBondContact OD1-NZ 2.91Å; Y198-K200 VanDerWaalsContact C-N 3.26Å; Y198-K200 PolarHBondContact O-N 3.08Å; K200-H204 WeakPolarHBondContact O-CB 3.46Å; K200-H204 PolarHBondContact O-N 2.95Å; K200-E240 HydrophobicContact CB-CB 4.11Å; K200-E240 HydrophobicContact CB-CG 4.43Å; K200-E240 HydrophobicContact CD-CB 4Å; K200-E240 HydrophobicContact CD-CG 4.14Å; K200-E240 HydrophobicContact CG-CB 4.08Å; K200-E243 HydrophobicContact CD-CB 4.23Å; K200-E243 HydrophobicContact CD-CG 4.36Å; K200-E243 WeakPolarHBondContact CD-OE2 3.15Å; K200-E243 VanDerWaalsContact CE-OE1 3.23Å; K200-E243 WeakPolarHBondContact CE-OE1 3.29Å; K200-E243 IonicContact NZ-OE1 3.07Å; K200-E243 PolarHBondContact NZ-OE1 3Å; K200-E243 IonicContact NZ-OE2 3.88Å; K200-E243 PolarHBondContact NZ-OE2 2.79Å; K200-I244 HydrophobicContact CB-CD1 4.37Å; K200-I244 HydrophobicContact CG-CD1 3.91Å; K200-I244 HydrophobicContact CG-CG1 3.67Å
201	T	98.5	Very high	97.1	Very high	38 Å²	38	37.5 Å²	37.5	23%	0.233	19%	0.186	C	C	.	.	H	α-helix	trans	-66.7	-45.7	-179.8	-59.1	0	0	0	0	111.1	I159 D197 Y198 L199 L203 H204 R205	I159-T201 HydrophobicContact CD1-CG2 3.77Å; I159-T201 HydrophobicContact CG1-CG2 4.23Å; I159-T201 HydrophobicContact CG2-CG2 4.31Å; D197-T201 PolarHBondContact O-N 3.2Å; D197-T201 PolarHBondContact O-OG1 2.99Å; Y198-T201 PolarHBondContact O-N 3.29Å; L199-T201 VanDerWaalsContact C-N 3.34Å; L199-T201 PolarHBondContact O-N 2.87Å; T201-L203 PolarHBondContact O-N 2.86Å; T201-H204 PolarHBondContact O-N 2.56Å; T201-R205 HydrophobicContact CG2-CG 4.48Å; T201-R205 VanDerWaalsContact O-CG 3.29Å; T201-R205 WeakPolarHBondContact O-CG 3.46Å; T201-R205 PolarHBondContact O-N 3.13Å
202	V	98.6	Very high	97.4	Very high	0 Å²	0	39.7 Å²	39.7	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-58	-50.3	177.4	170.9	0	0	0	0	111.2	Y155 F158 I159 L162 L184 Y198 L199 H204 R205 I206	Y155-V202 HydrophobicContact CD1-CG2 4.34Å; F158-V202 HydrophobicContact CD1-CG1 3.6Å; F158-V202 HydrophobicContact CD1-CG2 4Å; F158-V202 HydrophobicContact CE1-CG1 3.42Å; F158-V202 VanDerWaalsContact CE1-CG1 3.42Å; I159-V202 HydrophobicContact CD1-CG2 4.21Å; I159-V202 HydrophobicContact CG1-CG2 3.62Å; L162-V202 HydrophobicContact CD1-CG1 4.12Å; L184-V202 HydrophobicContact CD1-CG1 4.22Å; L184-V202 HydrophobicContact CD2-CG1 3.89Å; Y198-V202 WeakPolarHBondContact O-CG2 3.39Å; Y198-V202 PolarHBondContact O-N 3.43Å; L199-V202 PolarHBondContact O-N 3.46Å; V202-H204 PolarHBondContact O-N 3.32Å; V202-R205 PolarHBondContact O-N 3.38Å; V202-I206 HydrophobicContact CG1-CD1 3.83Å; V202-I206 WeakPolarHBondContact O-CG1 3.23Å; V202-I206 PolarHBondContact O-N 3.04Å
203	L	98.7	Very high	97.6	Very high	0 Å²	0	40.5 Å²	40.5	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-64.7	-40.2	-178.7	-178.1	65.3	0	0	0	111.5	L184 L185 F188 L199 T201 I206 Y207 I217 I221 L241 I244	L184-L203 HydrophobicContact CD2-CB 4.37Å; L184-L203 HydrophobicContact CD2-CD1 4.23Å; L185-L203 HydrophobicContact CD2-CD1 4.39Å; L185-L203 HydrophobicContact CD2-CD2 3.54Å; F188-L203 HydrophobicContact CE2-CB 4.07Å; F188-L203 HydrophobicContact CE2-CD2 3.66Å; F188-L203 HydrophobicContact CE2-CG 4.45Å; F188-L203 HydrophobicContact CZ-CB 3.89Å; F188-L203 HydrophobicContact CZ-CD2 3.63Å; F188-L203 HydrophobicContact CZ-CG 4.41Å; L199-L203 VanDerWaalsContact O-CB 3.32Å; L199-L203 WeakPolarHBondContact O-CB 3.08Å; L199-L203 PolarHBondContact O-N 2.95Å; T201-L203 PolarHBondContact O-N 2.86Å; L203-I206 PolarHBondContact O-N 2.93Å; L203-Y207 WeakPolarHBondContact O-CB 3.28Å; L203-Y207 PolarHBondContact O-N 3.46Å; L203-I217 HydrophobicContact CD1-CD1 4.28Å; L203-I217 HydrophobicContact CD1-CG1 4.39Å; L203-I217 HydrophobicContact CD1-CG2 4.18Å; L203-I221 HydrophobicContact CD2-CD1 4.45Å; L203-L241 HydrophobicContact CD2-CD2 3.93Å; L203-I244 HydrophobicContact CB-CD1 4.1Å; L203-I244 HydrophobicContact CD2-CD1 3.76Å; L203-I244 HydrophobicContact CG-CD1 4.19Å
204	H	98.4	Very high	97.7	Very high	57 Å²	57	42 Å²	42	26%	0.264	22%	0.219	S	C	.	.	H	α-helix	trans	-60.3	-45	174.9	-176.9	-110.8	0	0	0	112	K200 T201 V202 Y207 G208 I244 S247	K200-H204 WeakPolarHBondContact O-CB 3.46Å; K200-H204 PolarHBondContact O-N 2.95Å; T201-H204 PolarHBondContact O-N 2.56Å; V202-H204 PolarHBondContact O-N 3.32Å; H204-Y207 PolarHBondContact O-N 3.16Å; H204-G208 PolarHBondContact O-N 3.39Å; H204-I244 HydrophobicContact CB-CG1 4.48Å; H204-S247 PolarHBondContact NE2-OG 3.3Å
205	R	98	Very high	97.7	Very high	81 Å²	81	40.5 Å²	40.5	31%	0.306	23%	0.226	S	C	.	.	H	α-helix	trans	-64.2	-42	176.3	-65.6	-60.5	-176.5	-104.1	-0.8	112.2	L162 E163 T201 V202 G208 K209	L162-R205 HydrophobicContact CB-CB 4.32Å; L162-R205 HydrophobicContact CD1-CB 4.18Å; E163-R205 HydrophobicContact CG-CG 4.45Å; E163-R205 IonicContact OE1-CZ 3.79Å; E163-R205 IonicContact OE1-NE 2.89Å; E163-R205 PolarHBondContact OE1-NE 3.19Å; E163-R205 IonicContact OE1-NH2 3.27Å; E163-R205 PolarHBondContact OE1-NH2 3.46Å; T201-R205 HydrophobicContact CG2-CG 4.48Å; T201-R205 VanDerWaalsContact O-CG 3.29Å; T201-R205 WeakPolarHBondContact O-CG 3.46Å; T201-R205 PolarHBondContact O-N 3.13Å; V202-R205 PolarHBondContact O-N 3.38Å; R205-G208 PolarHBondContact O-N 3.36Å; R205-K209 WeakPolarHBondContact O-CB 3.29Å; R205-K209 WeakPolarHBondContact O-CG 3.32Å; R205-K209 PolarHBondContact O-N 3.13Å
206	I	98.4	Very high	97.8	Very high	0 Å²	0	42 Å²	42	0%	0	23%	0.233	C	C	.	.	H	α-helix	trans	-61.4	-47.5	175	-70.2	172	0	0	0	110.2	F158 L162 I176 F180 V181 L184 V202 L203 G208 K209 F210 L213 I217	F158-I206 HydrophobicContact CE1-CD1 4.33Å; L162-I206 HydrophobicContact CD1-CG1 4.02Å; L162-I206 HydrophobicContact CD2-CG1 4.43Å; I176-I206 HydrophobicContact CG2-CD1 4.42Å; I176-I206 HydrophobicContact CG2-CG2 4.37Å; F180-I206 HydrophobicContact CE1-CD1 4.01Å; V181-I206 HydrophobicContact CG2-CG2 4.31Å; L184-I206 HydrophobicContact CD2-CD1 3.72Å; V202-I206 HydrophobicContact CG1-CD1 3.83Å; V202-I206 WeakPolarHBondContact O-CG1 3.23Å; V202-I206 PolarHBondContact O-N 3.04Å; L203-I206 PolarHBondContact O-N 2.93Å; I206-G208 VanDerWaalsContact C-N 3.29Å; I206-G208 PolarHBondContact O-N 3.03Å; I206-K209 PolarHBondContact O-N 3.24Å; I206-F210 HydrophobicContact CB-CD2 4.31Å; I206-F210 HydrophobicContact CG2-CD2 3.83Å; I206-F210 HydrophobicContact CG2-CE2 4.47Å; I206-F210 WeakPolarHBondContact O-CB 3.48Å; I206-F210 WeakPolarHBondContact O-CD2 3.44Å; I206-F210 PolarHBondContact O-N 3.17Å; I206-L213 HydrophobicContact CG2-CD1 4.25Å; I206-I217 HydrophobicContact CG2-CD1 4.23Å
207	Y	98.1	Very high	97.8	Very high	17 Å²	17	40.4 Å²	40.4	7%	0.067	23%	0.226	C	C	.	.	H	α-helix	trans	-59.4	-41.4	177.6	-173.1	-85.5	0	0	0	112.3	L203 H204 R214 I217 R218 I248	L203-Y207 WeakPolarHBondContact O-CB 3.28Å; L203-Y207 PolarHBondContact O-N 3.46Å; H204-Y207 PolarHBondContact O-N 3.16Å; Y207-R214 HydrophobicContact CD1-CG 4.15Å; Y207-R214 HydrophobicContact CD2-CB 4.19Å; Y207-R214 HydrophobicContact CD2-CG 3.95Å; Y207-R214 HydrophobicContact CE1-CB 4.48Å; Y207-R214 HydrophobicContact CE1-CG 3.89Å; Y207-R214 HydrophobicContact CE2-CB 3.57Å; Y207-R214 HydrophobicContact CE2-CG 3.67Å; Y207-R214 HydrophobicContact CG-CG 4.18Å; Y207-R214 WeakPolarHBondContact O-CG 3.44Å; Y207-R214 PolarHBondContact O-NE 3.46Å; Y207-I217 HydrophobicContact CD2-CB 4.04Å; Y207-I217 HydrophobicContact CD2-CD1 3.86Å; Y207-I217 HydrophobicContact CD2-CG2 3.91Å; Y207-I217 HydrophobicContact CE2-CB 4.47Å; Y207-I217 HydrophobicContact CE2-CG2 4.49Å; Y207-I217 HydrophobicContact CG-CD1 4.48Å; Y207-R218 HydrophobicContact CE2-CG 4.07Å; Y207-R218 PolarHBondContact OH-NH1 3.17Å; Y207-I248 HydrophobicContact CD1-CD1 3.77Å; Y207-I248 HydrophobicContact CD1-CG1 3.7Å; Y207-I248 HydrophobicContact CD2-CD1 3.69Å; Y207-I248 HydrophobicContact CE1-CB 4.24Å; Y207-I248 HydrophobicContact CE1-CD1 3.71Å; Y207-I248 HydrophobicContact CE1-CG1 3.48Å; Y207-I248 VanDerWaalsContact CE1-CG1 3.48Å; Y207-I248 HydrophobicContact CE1-CG2 3.88Å; Y207-I248 HydrophobicContact CE2-CD1 3.62Å; Y207-I248 HydrophobicContact CE2-CG1 4.33Å; Y207-I248 HydrophobicContact CE2-CG2 4.5Å; Y207-I248 HydrophobicContact CG-CD1 3.77Å; Y207-I248 HydrophobicContact CG-CG1 4.22Å; Y207-I248 VanDerWaalsContact OH-CG2 3.24Å; Y207-I248 WeakPolarHBondContact OH-CG2 3.48Å
208	G	96.6	Very high	97.8	Very high	40 Å²	40	38.2 Å²	38.2	41%	0.412	21%	0.213	S	C	.	.	H	α-helix	trans	-60.9	-50.5	176.4	0	0	0	0	0	112.6	H204 R205 I206 R214	H204-G208 PolarHBondContact O-N 3.39Å; R205-G208 PolarHBondContact O-N 3.36Å; I206-G208 VanDerWaalsContact C-N 3.29Å; I206-G208 PolarHBondContact O-N 3.03Å; G208-R214 PolarHBondContact O-NH2 2.94Å; G208-R214 VanDerWaalsContact O-NH2 3.12Å
209	K	96.7	Very high	97.8	Very high	67 Å²	67	42 Å²	42	29%	0.291	23%	0.23	S	C	.	.	H	α-helix	trans	-83	-30	-171.4	-70	174.9	-177	-103.5	0	114.4	L162 F167 P169 R205 I206	L162-K209 WeakPolarHBondContact O-CD 3.48Å; L162-K209 WeakPolarHBondContact O-CE 3.35Å; L162-K209 PolarHBondContact O-NZ 3.44Å; F167-K209 HydrophobicContact CD1-CD 3.87Å; F167-K209 HydrophobicContact CE1-CB 4.42Å; F167-K209 HydrophobicContact CE1-CD 3.86Å; P169-K209 HydrophobicContact CG-CB 4.33Å; R205-K209 WeakPolarHBondContact O-CB 3.29Å; R205-K209 WeakPolarHBondContact O-CG 3.32Å; R205-K209 PolarHBondContact O-N 3.13Å; I206-K209 PolarHBondContact O-N 3.24Å
210	F	97.5	Very high	97.8	Very high	9 Å²	9	43.7 Å²	43.7	4%	0.039	24%	0.238	C	C	.	.			trans	-108.4	83.8	-175.4	-64.2	-81.9	0	0	0	112.3	F167 P169 A172 K173 I176 I206 G212 L213	F167-F210 HydrophobicContact CE1-CE2 4.29Å; F167-F210 HydrophobicContact CE1-CZ 4.06Å; F167-F210 HydrophobicContact CZ-CE2 4.05Å; F167-F210 AromaticContact CZ-CZ 3.71Å; F167-F210 HydrophobicContact CZ-CZ 3.71Å; P169-F210 HydrophobicContact CB-CD1 4.36Å; P169-F210 HydrophobicContact CB-CE1 4.14Å; A172-F210 HydrophobicContact CB-CE1 3.92Å; A172-F210 HydrophobicContact CB-CZ 3.6Å; K173-F210 HydrophobicContact CB-CD1 4.18Å; K173-F210 HydrophobicContact CB-CE1 4.04Å; I176-F210 HydrophobicContact CB-CE2 4.44Å; I176-F210 HydrophobicContact CB-CZ 4.13Å; I176-F210 HydrophobicContact CD1-CE2 3.99Å; I176-F210 HydrophobicContact CD1-CZ 3.87Å; I176-F210 HydrophobicContact CG1-CZ 4.49Å; I176-F210 HydrophobicContact CG2-CE2 4.18Å; I176-F210 HydrophobicContact CG2-CZ 4.35Å; I206-F210 HydrophobicContact CB-CD2 4.31Å; I206-F210 HydrophobicContact CG2-CD2 3.83Å; I206-F210 HydrophobicContact CG2-CE2 4.47Å; I206-F210 WeakPolarHBondContact O-CB 3.48Å; I206-F210 WeakPolarHBondContact O-CD2 3.44Å; I206-F210 PolarHBondContact O-N 3.17Å; F210-G212 PolarHBondContact O-N 3.4Å; F210-G212 VanDerWaalsContact O-N 3.14Å; F210-L213 HydrophobicContact CB-CB 4.05Å; F210-L213 HydrophobicContact CB-CD1 3.7Å; F210-L213 HydrophobicContact CB-CG 3.96Å; F210-L213 HydrophobicContact CD1-CD1 4.43Å; F210-L213 HydrophobicContact CD2-CD1 4.46Å; F210-L213 HydrophobicContact CG-CD1 3.97Å; F210-L213 PolarHBondContact O-N 3.14Å
211	L	95.7	Very high	97.7	Very high	122 Å²	122	42.3 Å²	42.3	64%	0.639	23%	0.232	S	C	*	.	G	3₁₀ helix	trans	-52.8	-39	179.7	-57.9	-176	0	0	0	113.2	L213 R214	L211-L213 VanDerWaalsContact C-N 3.27Å; L211-L213 PolarHBondContact O-N 3.35Å; L211-R214 VanDerWaalsContact CD2-NH2 3.27Å; L211-R214 WeakPolarHBondContact O-CB 3.31Å; L211-R214 PolarHBondContact O-N 3.25Å
212	G	96.6	Very high	97.7	Very high	74 Å²	74	42.3 Å²	42.3	76%	0.763	23%	0.231	S	C	*	.	G	3₁₀ helix	trans	-69	-18.4	179.8	0	0	0	0	0	115.1	F210	F210-G212 PolarHBondContact O-N 3.4Å; F210-G212 VanDerWaalsContact O-N 3.14Å
213	L	97.9	Very high	97.7	Very high	17 Å²	17	45.8 Å²	45.8	9%	0.089	25%	0.249	C	C	.	.	G	3₁₀ helix	trans	-93.2	-14.3	178.2	-64.9	176.9	0	0	0	112.8	I176 Q178 V181 I206 F210 L211 A215 F216 I217	I176-L213 HydrophobicContact CG2-CD1 4.18Å; Q178-L213 HydrophobicContact CG-CD2 4.03Å; V181-L213 HydrophobicContact CG2-CD1 3.92Å; I206-L213 HydrophobicContact CG2-CD1 4.25Å; F210-L213 HydrophobicContact CB-CB 4.05Å; F210-L213 HydrophobicContact CB-CD1 3.7Å; F210-L213 HydrophobicContact CB-CG 3.96Å; F210-L213 HydrophobicContact CD1-CD1 4.43Å; F210-L213 HydrophobicContact CD2-CD1 4.46Å; F210-L213 HydrophobicContact CG-CD1 3.97Å; F210-L213 PolarHBondContact O-N 3.14Å; L211-L213 VanDerWaalsContact C-N 3.27Å; L211-L213 PolarHBondContact O-N 3.35Å; L213-A215 PolarHBondContact O-N 3.5Å; L213-F216 WeakPolarHBondContact O-CB 3.31Å; L213-F216 PolarHBondContact O-N 3.12Å; L213-F216 VanDerWaalsContact O-N 3.08Å; L213-I217 HydrophobicContact CB-CD1 4.12Å; L213-I217 WeakPolarHBondContact O-CG1 3.47Å; L213-I217 PolarHBondContact O-N 3.39Å
214	R	97.5	Very high	97.6	Very high	83 Å²	83	47.3 Å²	47.3	31%	0.313	26%	0.257	S	S	.	.	H	α-helix	trans	-55.9	-46.7	-173.6	-69.3	-173.6	174	-178.6	2.3	113.5	Y207 G208 L211 F216 I217 R218	Y207-R214 HydrophobicContact CD1-CG 4.15Å; Y207-R214 HydrophobicContact CD2-CB 4.19Å; Y207-R214 HydrophobicContact CD2-CG 3.95Å; Y207-R214 HydrophobicContact CE1-CB 4.48Å; Y207-R214 HydrophobicContact CE1-CG 3.89Å; Y207-R214 HydrophobicContact CE2-CB 3.57Å; Y207-R214 HydrophobicContact CE2-CG 3.67Å; Y207-R214 HydrophobicContact CG-CG 4.18Å; Y207-R214 WeakPolarHBondContact O-CG 3.44Å; Y207-R214 PolarHBondContact O-NE 3.46Å; G208-R214 PolarHBondContact O-NH2 2.94Å; G208-R214 VanDerWaalsContact O-NH2 3.12Å; L211-R214 VanDerWaalsContact CD2-NH2 3.27Å; L211-R214 WeakPolarHBondContact O-CB 3.31Å; L211-R214 PolarHBondContact O-N 3.25Å; R214-F216 VanDerWaalsContact C-N 3.32Å; R214-F216 PolarHBondContact O-N 2.9Å; R214-I217 PolarHBondContact O-N 2.98Å; R214-R218 WeakPolarHBondContact O-CG 3.38Å; R214-R218 PolarHBondContact O-N 3.26Å; R214-R218 PolarHBondContact O-NH1 3.48Å
215	A	96.6	Very high	97.6	Very high	58 Å²	58	44.6 Å²	44.6	48%	0.479	24%	0.244	S	C	.	.	H	α-helix	trans	-64.2	-39.3	179.3	0	0	0	0	0	111.9	L213 K219	L213-A215 PolarHBondContact O-N 3.5Å; A215-K219 WeakPolarHBondContact O-CB 3.46Å; A215-K219 PolarHBondContact O-N 2.97Å
216	F	98.2	Very high	97.6	Very high	31 Å²	31	43.8 Å²	43.8	14%	0.136	25%	0.246	C	C	.	.	H	α-helix	trans	-66.1	-47	176.8	-179.4	-97.5	0	0	0	111.6	Q178 V181 L213 R214 R218 K219 Q220	Q178-F216 HydrophobicContact CB-CD1 4.03Å; Q178-F216 HydrophobicContact CB-CD2 4.19Å; Q178-F216 HydrophobicContact CB-CE1 3.75Å; Q178-F216 HydrophobicContact CB-CE2 3.91Å; Q178-F216 HydrophobicContact CB-CG 4.24Å; Q178-F216 HydrophobicContact CB-CZ 3.69Å; Q178-F216 VanDerWaalsContact CD-CD2 3.42Å; Q178-F216 HydrophobicContact CG-CB 4.27Å; Q178-F216 HydrophobicContact CG-CD1 3.88Å; Q178-F216 HydrophobicContact CG-CD2 3.81Å; Q178-F216 HydrophobicContact CG-CE1 4.14Å; Q178-F216 HydrophobicContact CG-CE2 4.06Å; Q178-F216 HydrophobicContact CG-CG 3.71Å; Q178-F216 HydrophobicContact CG-CZ 4.22Å; Q178-F216 VanDerWaalsContact O-CE1 3.23Å; Q178-F216 WeakPolarHBondContact O-CE1 3.5Å; V181-F216 HydrophobicContact CB-CD1 4.31Å; V181-F216 HydrophobicContact CB-CE1 4.13Å; V181-F216 HydrophobicContact CG1-CD1 3.95Å; V181-F216 HydrophobicContact CG1-CE1 3.95Å; L213-F216 WeakPolarHBondContact O-CB 3.31Å; L213-F216 PolarHBondContact O-N 3.12Å; L213-F216 VanDerWaalsContact O-N 3.08Å; R214-F216 VanDerWaalsContact C-N 3.32Å; R214-F216 PolarHBondContact O-N 2.9Å; F216-R218 PolarHBondContact O-N 2.85Å; F216-K219 PolarHBondContact O-N 3.39Å; F216-Q220 HydrophobicContact CD1-CG 4.1Å; F216-Q220 HydrophobicContact CD2-CG 4.45Å; F216-Q220 HydrophobicContact CE1-CG 3.66Å; F216-Q220 HydrophobicContact CE2-CG 4.05Å; F216-Q220 HydrophobicContact CG-CG 4.48Å; F216-Q220 HydrophobicContact CZ-CG 3.63Å; F216-Q220 WeakPolarHBondContact O-CG 3.3Å; F216-Q220 PolarHBondContact O-N 2.96Å
217	I	98.5	Very high	97.5	Very high	0 Å²	0	51 Å²	51	0%	0	27%	0.273	C	S	.	.	H	α-helix	trans	-56.5	-51.2	176.9	-68.1	164.2	0	0	0	110.5	V181 L203 I206 Y207 L213 R214 K219 Q220 I221	V181-I217 HydrophobicContact CG1-CD1 4.45Å; V181-I217 HydrophobicContact CG1-CG1 3.59Å; L203-I217 HydrophobicContact CD1-CD1 4.28Å; L203-I217 HydrophobicContact CD1-CG1 4.39Å; L203-I217 HydrophobicContact CD1-CG2 4.18Å; I206-I217 HydrophobicContact CG2-CD1 4.23Å; Y207-I217 HydrophobicContact CD2-CB 4.04Å; Y207-I217 HydrophobicContact CD2-CD1 3.86Å; Y207-I217 HydrophobicContact CD2-CG2 3.91Å; Y207-I217 HydrophobicContact CE2-CB 4.47Å; Y207-I217 HydrophobicContact CE2-CG2 4.49Å; Y207-I217 HydrophobicContact CG-CD1 4.48Å; L213-I217 HydrophobicContact CB-CD1 4.12Å; L213-I217 WeakPolarHBondContact O-CG1 3.47Å; L213-I217 PolarHBondContact O-N 3.39Å; R214-I217 PolarHBondContact O-N 2.98Å; I217-K219 VanDerWaalsContact C-N 3.31Å; I217-K219 PolarHBondContact O-N 3.44Å; I217-Q220 PolarHBondContact O-N 3.36Å; I217-I221 HydrophobicContact CG2-CD1 3.74Å; I217-I221 HydrophobicContact CG2-CG1 4.38Å; I217-I221 WeakPolarHBondContact O-CG1 3.48Å; I217-I221 PolarHBondContact O-N 3.04Å
218	R	98	Very high	97.5	Very high	30 Å²	30	50.3 Å²	50.3	11%	0.113	27%	0.27	C	S	.	.	H	α-helix	trans	-58	-44	177.5	-68.7	-166.3	-55.3	-82.4	3.5	111.8	Y207 R214 F216 Q220 I221 N222 E259	Y207-R218 HydrophobicContact CE2-CG 4.07Å; Y207-R218 PolarHBondContact OH-NH1 3.17Å; R214-R218 WeakPolarHBondContact O-CG 3.38Å; R214-R218 PolarHBondContact O-N 3.26Å; R214-R218 PolarHBondContact O-NH1 3.48Å; F216-R218 PolarHBondContact O-N 2.85Å; R218-Q220 PolarHBondContact O-N 3.46Å; R218-I221 PolarHBondContact O-N 3.21Å; R218-N222 WeakPolarHBondContact O-CB 3.43Å; R218-N222 PolarHBondContact O-N 2.92Å; R218-N222 PolarHBondContact O-OD1 3.14Å; R218-E259 IonicContact CZ-OE1 2.76Å; R218-E259 IonicContact NH2-OE1 2.83Å; R218-E259 PolarHBondContact NH2-OE1 2.97Å
219	K	97.7	Very high	97.5	Very high	130 Å²	130	49 Å²	49	57%	0.565	26%	0.255	S	S	*	.	H	α-helix	trans	-61.2	-42.9	177.8	-175.3	179.5	178.7	-178.1	0	112.1	A215 F216 I217 N222 N223	A215-K219 WeakPolarHBondContact O-CB 3.46Å; A215-K219 PolarHBondContact O-N 2.97Å; F216-K219 PolarHBondContact O-N 3.39Å; I217-K219 VanDerWaalsContact C-N 3.31Å; I217-K219 PolarHBondContact O-N 3.44Å; K219-N222 WeakPolarHBondContact O-CB 3.44Å; K219-N222 PolarHBondContact O-N 2.98Å; K219-N223 PolarHBondContact O-N 3.19Å; K219-N223 PolarHBondContact O-ND2 3.36Å; K219-N223 PolarHBondContact O-OD1 3.2Å
220	Q	98.2	Very high	97.4	Very high	35 Å²	35	52.9 Å²	52.9	16%	0.164	27%	0.268	C	S	.	.	H	α-helix	trans	-70.8	-40.2	179.8	-64.8	-53.2	-19.6	0	0	112.5	L185 F216 I217 R218 N222 N223 I224	L185-Q220 HydrophobicContact CD1-CB 3.45Å; L185-Q220 VanDerWaalsContact CD1-CB 3.45Å; L185-Q220 HydrophobicContact CD1-CG 4.23Å; F216-Q220 HydrophobicContact CD1-CG 4.1Å; F216-Q220 HydrophobicContact CD2-CG 4.45Å; F216-Q220 HydrophobicContact CE1-CG 3.66Å; F216-Q220 HydrophobicContact CE2-CG 4.05Å; F216-Q220 HydrophobicContact CG-CG 4.48Å; F216-Q220 HydrophobicContact CZ-CG 3.63Å; F216-Q220 WeakPolarHBondContact O-CG 3.3Å; F216-Q220 PolarHBondContact O-N 2.96Å; I217-Q220 PolarHBondContact O-N 3.36Å; R218-Q220 PolarHBondContact O-N 3.46Å; Q220-N222 VanDerWaalsContact C-N 3.28Å; Q220-N222 PolarHBondContact O-N 3.24Å; Q220-N223 WeakPolarHBondContact O-CB 3.23Å; Q220-N223 PolarHBondContact O-N 3.34Å; Q220-N223 VanDerWaalsContact O-N 3.14Å; Q220-N223 PolarHBondContact OE1-ND2 3.02Å; Q220-N223 VanDerWaalsContact OE1-ND2 3.14Å; Q220-I224 WeakPolarHBondContact O-CG1 3.36Å; Q220-I224 PolarHBondContact O-N 3.38Å
221	I	98.5	Very high	97.3	Very high	0 Å²	0	59.5 Å²	59.5	0%	0	30%	0.299	C	S	.	.	H	α-helix	trans	-60	-42	172.5	-64.9	172.1	0	0	0	110.4	L185 L203 I217 R218 N223 I224 F225 L241 L245	L185-I221 HydrophobicContact CD2-CG1 4.06Å; L203-I221 HydrophobicContact CD2-CD1 4.45Å; I217-I221 HydrophobicContact CG2-CD1 3.74Å; I217-I221 HydrophobicContact CG2-CG1 4.38Å; I217-I221 WeakPolarHBondContact O-CG1 3.48Å; I217-I221 PolarHBondContact O-N 3.04Å; R218-I221 PolarHBondContact O-N 3.21Å; I221-N223 VanDerWaalsContact C-N 3.34Å; I221-N223 PolarHBondContact O-N 3.11Å; I221-I224 PolarHBondContact O-N 3.18Å; I221-F225 HydrophobicContact CG2-CD2 4.01Å; I221-F225 HydrophobicContact CG2-CE1 4.24Å; I221-F225 HydrophobicContact CG2-CE2 3.68Å; I221-F225 HydrophobicContact CG2-CG 4.45Å; I221-F225 HydrophobicContact CG2-CZ 3.8Å; I221-F225 WeakPolarHBondContact O-CG 3.36Å; I221-F225 PolarHBondContact O-N 2.94Å; I221-L241 HydrophobicContact CD1-CD2 4.21Å; I221-L241 HydrophobicContact CG1-CD2 4.19Å; I221-L241 HydrophobicContact CG2-CB 4.5Å; I221-L241 HydrophobicContact CG2-CD1 4.43Å; I221-L245 HydrophobicContact CG2-CD1 3.69Å; I221-L245 HydrophobicContact CG2-CG 4.35Å
222	N	97.6	Very high	97.2	Very high	38 Å²	38	56.5 Å²	56.5	20%	0.203	29%	0.286	C	S	.	.	H	α-helix	trans	-59.2	-44.1	174.3	-68.4	3.7	0	0	0	112	R218 K219 Q220 I224 F225 L226 F263	R218-N222 WeakPolarHBondContact O-CB 3.43Å; R218-N222 PolarHBondContact O-N 2.92Å; R218-N222 PolarHBondContact O-OD1 3.14Å; K219-N222 WeakPolarHBondContact O-CB 3.44Å; K219-N222 PolarHBondContact O-N 2.98Å; Q220-N222 VanDerWaalsContact C-N 3.28Å; Q220-N222 PolarHBondContact O-N 3.24Å; N222-I224 VanDerWaalsContact C-N 3.34Å; N222-I224 PolarHBondContact O-N 3.35Å; N222-F225 PolarHBondContact O-N 3.12Å; N222-L226 WeakPolarHBondContact O-CB 3.22Å; N222-L226 VanDerWaalsContact O-CG 3.25Å; N222-L226 WeakPolarHBondContact O-CG 3.25Å; N222-L226 PolarHBondContact O-N 3.42Å; N222-F263 WeakPolarHBondContact OD1-CD2 3.3Å; N222-F263 WeakPolarHBondContact OD1-CE2 3.49Å
223	N	97.7	Very high	96.9	Very high	72 Å²	72	57 Å²	57	39%	0.385	27%	0.269	S	S	.	.	H	α-helix	trans	-62	-42.7	177.5	-65.7	-21.5	0	0	0	111.6	K219 Q220 I221 L226 R227	K219-N223 PolarHBondContact O-N 3.19Å; K219-N223 PolarHBondContact O-ND2 3.36Å; K219-N223 PolarHBondContact O-OD1 3.2Å; Q220-N223 WeakPolarHBondContact O-CB 3.23Å; Q220-N223 PolarHBondContact O-N 3.34Å; Q220-N223 VanDerWaalsContact O-N 3.14Å; Q220-N223 PolarHBondContact OE1-ND2 3.02Å; Q220-N223 VanDerWaalsContact OE1-ND2 3.14Å; I221-N223 VanDerWaalsContact C-N 3.34Å; I221-N223 PolarHBondContact O-N 3.11Å; N223-L226 PolarHBondContact O-N 2.92Å; N223-R227 WeakPolarHBondContact O-CB 3.39Å; N223-R227 PolarHBondContact O-N 2.94Å
224	I	98.1	Very high	96.5	Very high	33 Å²	33	59.3 Å²	59.3	17%	0.169	28%	0.279	C	S	.	.	H	α-helix	trans	-59.2	-49.4	176.1	-69.2	166.4	0	0	0	109.9	L185 Q220 I221 N222 L226 R227 F228 F235 L241	L185-I224 HydrophobicContact CB-CD1 4.16Å; L185-I224 HydrophobicContact CD2-CD1 4.36Å; Q220-I224 WeakPolarHBondContact O-CG1 3.36Å; Q220-I224 PolarHBondContact O-N 3.38Å; I221-I224 PolarHBondContact O-N 3.18Å; N222-I224 VanDerWaalsContact C-N 3.34Å; N222-I224 PolarHBondContact O-N 3.35Å; I224-L226 PolarHBondContact O-N 3.17Å; I224-R227 PolarHBondContact O-N 3.14Å; I224-F228 WeakPolarHBondContact O-CB 3.44Å; I224-F228 PolarHBondContact O-N 2.63Å; I224-F235 HydrophobicContact CD1-CZ 4.44Å; I224-F235 HydrophobicContact CG2-CD1 4Å; I224-F235 HydrophobicContact CG2-CD2 3.98Å; I224-F235 HydrophobicContact CG2-CE1 3.84Å; I224-F235 HydrophobicContact CG2-CE2 3.79Å; I224-F235 HydrophobicContact CG2-CG 4.07Å; I224-F235 HydrophobicContact CG2-CZ 3.72Å; I224-L241 HydrophobicContact CD1-CD1 4.4Å; I224-L241 HydrophobicContact CG2-CD1 4.18Å
225	F	98.3	Very high	96.3	Very high	0 Å²	0	56.9 Å²	56.9	0%	0	27%	0.271	C	S	.	.	H	α-helix	trans	-65.8	-39.4	179.6	-70.2	-13.1	0	0	0	113.4	I221 N222 F228 V229 V238 L241 L242 L245 F263 V267 L271	I221-F225 HydrophobicContact CG2-CD2 4.01Å; I221-F225 HydrophobicContact CG2-CE1 4.24Å; I221-F225 HydrophobicContact CG2-CE2 3.68Å; I221-F225 HydrophobicContact CG2-CG 4.45Å; I221-F225 HydrophobicContact CG2-CZ 3.8Å; I221-F225 WeakPolarHBondContact O-CG 3.36Å; I221-F225 PolarHBondContact O-N 2.94Å; N222-F225 PolarHBondContact O-N 3.12Å; F225-F228 PolarHBondContact O-N 3.36Å; F225-V229 WeakPolarHBondContact O-CB 3.46Å; F225-V229 VanDerWaalsContact O-CG2 3.29Å; F225-V229 WeakPolarHBondContact O-CG2 3.37Å; F225-V229 PolarHBondContact O-N 3.11Å; F225-V238 HydrophobicContact CE1-CG1 4.11Å; F225-L241 HydrophobicContact CE1-CB 3.96Å; F225-L241 HydrophobicContact CE1-CD1 4Å; F225-L241 HydrophobicContact CZ-CB 3.81Å; F225-L242 HydrophobicContact CE2-CD2 3.82Å; F225-L242 HydrophobicContact CE2-CG 4.37Å; F225-L242 HydrophobicContact CZ-CD2 3.88Å; F225-L242 HydrophobicContact CZ-CG 3.91Å; F225-L245 HydrophobicContact CD2-CD1 4.4Å; F225-L245 HydrophobicContact CE2-CD1 3.35Å; F225-L245 HydrophobicContact CZ-CD1 3.84Å; F225-F263 HydrophobicContact CD2-CE2 4.27Å; F225-F263 HydrophobicContact CD2-CZ 4.46Å; F225-F263 HydrophobicContact CE2-CZ 4.41Å; F225-V267 HydrophobicContact CB-CG1 3.45Å; F225-V267 VanDerWaalsContact CB-CG1 3.45Å; F225-V267 HydrophobicContact CD2-CG1 3.74Å; F225-V267 HydrophobicContact CG-CG1 4.12Å; F225-L271 HydrophobicContact CB-CD2 4.46Å; F225-L271 HydrophobicContact CD2-CD1 3.94Å; F225-L271 HydrophobicContact CE2-CD1 4.13Å; F225-L271 HydrophobicContact CG-CD1 4.27Å; F225-L271 HydrophobicContact CG-CD2 4.49Å
226	L	97.5	Very high	96.2	Very high	64 Å²	64	55.6 Å²	55.6	34%	0.335	26%	0.256	S	S	.	.	H	α-helix	trans	-63.4	-43.4	175.5	-71.8	172.9	0	0	0	111.2	N222 N223 I224 V229 Y230 V267	N222-L226 WeakPolarHBondContact O-CB 3.22Å; N222-L226 VanDerWaalsContact O-CG 3.25Å; N222-L226 WeakPolarHBondContact O-CG 3.25Å; N222-L226 PolarHBondContact O-N 3.42Å; N223-L226 PolarHBondContact O-N 2.92Å; I224-L226 PolarHBondContact O-N 3.17Å; L226-V229 PolarHBondContact O-N 2.83Å; L226-Y230 HydrophobicContact CD2-CD2 4.05Å; L226-Y230 HydrophobicContact CD2-CE2 3.65Å; L226-Y230 WeakPolarHBondContact O-CB 3.35Å; L226-Y230 VanDerWaalsContact O-CD2 3.28Å; L226-Y230 WeakPolarHBondContact O-CD2 3.47Å; L226-Y230 PolarHBondContact O-N 3.17Å; L226-V267 HydrophobicContact CD2-CG2 4.16Å; L226-V267 HydrophobicContact CG-CG2 4.37Å
227	R	97.3	Very high	96.1	Very high	150 Å²	150	54.1 Å²	54.1	57%	0.566	25%	0.249	S	C	*	.	H	α-helix	trans	-63	-43.4	174.7	-175.8	174.2	-175.1	-159.2	-5.2	111.6	N223 I224 E231 T232	N223-R227 WeakPolarHBondContact O-CB 3.39Å; N223-R227 PolarHBondContact O-N 2.94Å; I224-R227 PolarHBondContact O-N 3.14Å; R227-E231 HydrophobicContact CG-CB 4.14Å; R227-E231 IonicContact NE-OE2 2.92Å; R227-E231 WeakPolarHBondContact O-CA 3.4Å; R227-E231 VanDerWaalsContact O-CB 3.31Å; R227-E231 WeakPolarHBondContact O-CB 3.47Å; R227-E231 PolarHBondContact O-N 3.41Å; R227-T232 HydrophobicContact CG-CG2 4.03Å; R227-T232 PolarHBondContact O-N 3.37Å
228	F	96.5	Very high	96	Very high	3 Å²	3	54.3 Å²	54.3	1%	0.013	25%	0.25	C	S	.	.	I	π-helix	trans	-58.8	-49.2	176.1	171.6	-114.6	0	0	0	111.8	I224 F225 E233 F235 V238 L271 V274 F280	I224-F228 WeakPolarHBondContact O-CB 3.44Å; I224-F228 PolarHBondContact O-N 2.63Å; F225-F228 PolarHBondContact O-N 3.36Å; F228-E233 VanDerWaalsContact CE2-C 3.49Å; F228-E233 WeakPolarHBondContact O-CA 3.45Å; F228-E233 PolarHBondContact O-N 3Å; F228-F235 HydrophobicContact CB-CB 4.49Å; F228-F235 HydrophobicContact CD2-CB 3.87Å; F228-F235 HydrophobicContact CG-CB 4.38Å; F228-V238 HydrophobicContact CD1-CG2 4.02Å; F228-V238 HydrophobicContact CD2-CG2 4.32Å; F228-V238 HydrophobicContact CE1-CG1 4.42Å; F228-V238 HydrophobicContact CE1-CG2 3.91Å; F228-V238 HydrophobicContact CE2-CG2 4.23Å; F228-V238 HydrophobicContact CG-CG2 4.22Å; F228-V238 HydrophobicContact CZ-CG2 4.03Å; F228-L271 HydrophobicContact CD1-CD2 3.61Å; F228-L271 HydrophobicContact CE1-CD2 3.82Å; F228-V274 HydrophobicContact CD1-CG1 4.4Å; F228-V274 HydrophobicContact CE1-CB 4.22Å; F228-V274 HydrophobicContact CE1-CG1 3.9Å; F228-V274 HydrophobicContact CE1-CG2 3.74Å; F228-V274 HydrophobicContact CZ-CB 4.18Å; F228-V274 HydrophobicContact CZ-CG1 4.19Å; F228-V274 HydrophobicContact CZ-CG2 3.86Å; F228-F280 HydrophobicContact CE1-CE1 4.05Å; F228-F280 AromaticContact CE1-CZ 3.93Å; F228-F280 HydrophobicContact CE1-CZ 3.93Å; F228-F280 AromaticContact CZ-CE1 3.93Å; F228-F280 HydrophobicContact CZ-CE1 3.93Å; F228-F280 HydrophobicContact CZ-CZ 4.21Å
229	V	96.6	Very high	96	Very high	14 Å²	14	53.7 Å²	53.7	9%	0.085	25%	0.252	C	S	.	.	I	π-helix	trans	-71	-40.7	-176.7	174.1	0	0	0	0	112.7	F225 L226 P270 L271 V274	F225-V229 WeakPolarHBondContact O-CB 3.46Å; F225-V229 VanDerWaalsContact O-CG2 3.29Å; F225-V229 WeakPolarHBondContact O-CG2 3.37Å; F225-V229 PolarHBondContact O-N 3.11Å; L226-V229 PolarHBondContact O-N 2.83Å; V229-P270 HydrophobicContact CG1-CB 4.1Å; V229-L271 HydrophobicContact CG2-CD2 3.48Å; V229-L271 VanDerWaalsContact CG2-CD2 3.48Å; V229-L271 HydrophobicContact CG2-CG 4.05Å; V229-V274 HydrophobicContact CB-CG1 4.49Å; V229-V274 HydrophobicContact CG2-CG1 4.18Å
230	Y	96	Very high	96.1	Very high	148 Å²	148	48.5 Å²	48.5	58%	0.58	23%	0.23	S	C	*	.	I	π-helix	trans	-108.3	-13.1	-167	-61.1	-65.7	0	0	0	115	L226	L226-Y230 HydrophobicContact CD2-CD2 4.05Å; L226-Y230 HydrophobicContact CD2-CE2 3.65Å; L226-Y230 WeakPolarHBondContact O-CB 3.35Å; L226-Y230 VanDerWaalsContact O-CD2 3.28Å; L226-Y230 WeakPolarHBondContact O-CD2 3.47Å; L226-Y230 PolarHBondContact O-N 3.17Å
231	E	95.6	Very high	96.1	Very high	147 Å²	147	46.9 Å²	46.9	69%	0.687	22%	0.222	S	C	*	.	I	π-helix	trans	-124.4	-56.5	-175.5	-59.4	178.3	-158.7	0	0	113.4	R227	R227-E231 HydrophobicContact CG-CB 4.14Å; R227-E231 IonicContact NE-OE2 2.92Å; R227-E231 WeakPolarHBondContact O-CA 3.4Å; R227-E231 VanDerWaalsContact O-CB 3.31Å; R227-E231 WeakPolarHBondContact O-CB 3.47Å; R227-E231 PolarHBondContact O-N 3.41Å
232	T	91.6	Very high	96.1	Very high	59 Å²	59	46.9 Å²	46.9	36%	0.362	22%	0.222	S	C	.	.	I	π-helix	trans	-100.6	-30.2	-166.6	61.9	0	0	0	0	114.2	R227 H234	R227-T232 HydrophobicContact CG-CG2 4.03Å; R227-T232 PolarHBondContact O-N 3.37Å; T232-H234 PolarHBondContact O-N 3.23Å; T232-H234 PolarHBondContact OG1-N 2.95Å; T232-H234 PolarHBondContact OG1-O 2.93Å
233	E	90.3	Very high	96.1	Very high	86 Å²	86	49.4 Å²	49.4	40%	0.402	23%	0.232	S	C	.	.	S	Bend	trans	48	19.7	-166.1	-69	-164.2	96.6	0	0	113.8	F228 R275	F228-E233 VanDerWaalsContact CE2-C 3.49Å; F228-E233 WeakPolarHBondContact O-CA 3.45Å; F228-E233 PolarHBondContact O-N 3Å; E233-R275 IonicContact OE2-NE 2.72Å
234	H	90.3	Very high	96.2	Very high	65 Å²	65	46.1 Å²	46.1	30%	0.301	22%	0.215	S	C	.	.			trans	-140.7	123.2	-178.3	-176.2	76	0	0	0	109.8	T232	T232-H234 PolarHBondContact O-N 3.23Å; T232-H234 PolarHBondContact OG1-N 2.95Å; T232-H234 PolarHBondContact OG1-O 2.93Å
235	F	94.1	Very high	96.2	Very high	31 Å²	31	44.7 Å²	44.7	14%	0.136	21%	0.207	C	C	.	.			trans	-168.1	123.4	169.4	-173	-100.3	0	0	0	107.8	F188 D189 I224 F228 V238 L241	F188-F235 HydrophobicContact CB-CE1 4.02Å; F188-F235 HydrophobicContact CB-CZ 3.67Å; D189-F235 HydrophobicContact CB-CD2 4Å; D189-F235 HydrophobicContact CB-CE2 3.74Å; D189-F235 HydrophobicContact CB-CZ 4.44Å; D189-F235 VanDerWaalsContact OD1-CA 3.29Å; D189-F235 WeakPolarHBondContact OD1-CA 3.23Å; I224-F235 HydrophobicContact CD1-CZ 4.44Å; I224-F235 HydrophobicContact CG2-CD1 4Å; I224-F235 HydrophobicContact CG2-CD2 3.98Å; I224-F235 HydrophobicContact CG2-CE1 3.84Å; I224-F235 HydrophobicContact CG2-CE2 3.79Å; I224-F235 HydrophobicContact CG2-CG 4.07Å; I224-F235 HydrophobicContact CG2-CZ 3.72Å; F228-F235 HydrophobicContact CB-CB 4.49Å; F228-F235 HydrophobicContact CD2-CB 3.87Å; F228-F235 HydrophobicContact CG-CB 4.38Å; F235-V238 HydrophobicContact CB-CG2 4.04Å; F235-V238 HydrophobicContact CD1-CG2 3.79Å; F235-V238 HydrophobicContact CG-CG2 4.4Å; F235-L241 HydrophobicContact CE1-CD1 3.62Å; F235-L241 HydrophobicContact CE1-CG 4.47Å; F235-L241 HydrophobicContact CZ-CD1 4.12Å
236	N	93.2	Very high	96.2	Very high	32 Å²	32	44.7 Å²	44.7	17%	0.171	21%	0.207	C	C	.	.	T	Hydrogen-bonded Turn	trans	-73.4	-30.7	-171.1	-67.9	-51.1	0	0	0	113.6	D189 V238	D189-N236 PolarHBondContact O-ND2 3.36Å; D189-N236 PolarHBondContact OD1-N 3.46Å; N236-V238 PolarHBondContact O-N 3.18Å
237	G	96.3	Very high	96.2	Very high	0 Å²	0	44.1 Å²	44.1	0%	0	21%	0.209	C	C	.	.	T	Hydrogen-bonded Turn	trans	-94.5	23.8	-171.2	0	0	0	0	0	116.6	F188 E240 L241	F188-G237 VanDerWaalsContact O-CA 3.23Å; F188-G237 WeakPolarHBondContact O-CA 3.36Å; F188-G237 PolarHBondContact O-N 2.9Å; F188-G237 VanDerWaalsContact O-N 3.13Å; G237-E240 VanDerWaalsContact CA-OE2 3.29Å; G237-E240 WeakPolarHBondContact CA-OE2 3.48Å; G237-L241 WeakPolarHBondContact O-CG 3.46Å; G237-L241 PolarHBondContact O-N 3.18Å; G237-L241 VanDerWaalsContact O-N 3.13Å
238	V	97.8	Very high	96.2	Very high	3 Å²	3	37.4 Å²	37.4	2%	0.018	18%	0.184	C	C	.	.	H	α-helix	trans	-63	-43	-177.3	178.3	0	0	0	0	111.2	F225 F228 F235 N236 E240 L241 L242 F280	F225-V238 HydrophobicContact CE1-CG1 4.11Å; F228-V238 HydrophobicContact CD1-CG2 4.02Å; F228-V238 HydrophobicContact CD2-CG2 4.32Å; F228-V238 HydrophobicContact CE1-CG1 4.42Å; F228-V238 HydrophobicContact CE1-CG2 3.91Å; F228-V238 HydrophobicContact CE2-CG2 4.23Å; F228-V238 HydrophobicContact CG-CG2 4.22Å; F228-V238 HydrophobicContact CZ-CG2 4.03Å; F235-V238 HydrophobicContact CB-CG2 4.04Å; F235-V238 HydrophobicContact CD1-CG2 3.79Å; F235-V238 HydrophobicContact CG-CG2 4.4Å; N236-V238 PolarHBondContact O-N 3.18Å; V238-E240 PolarHBondContact O-N 3.01Å; V238-L241 PolarHBondContact O-N 3.39Å; V238-L242 HydrophobicContact CG1-CD1 3.84Å; V238-L242 HydrophobicContact CG1-CG 4.32Å; V238-L242 WeakPolarHBondContact O-CB 3.37Å; V238-L242 WeakPolarHBondContact O-CG 3.35Å; V238-L242 PolarHBondContact O-N 3.21Å; V238-F280 HydrophobicContact CB-CD1 3.96Å; V238-F280 HydrophobicContact CB-CE1 4.39Å; V238-F280 HydrophobicContact CB-CG 4.22Å; V238-F280 HydrophobicContact CG1-CB 4.2Å; V238-F280 HydrophobicContact CG1-CD1 3.73Å; V238-F280 HydrophobicContact CG1-CD2 3.85Å; V238-F280 HydrophobicContact CG1-CE1 4.01Å; V238-F280 HydrophobicContact CG1-CE2 4.13Å; V238-F280 HydrophobicContact CG1-CG 3.64Å; V238-F280 HydrophobicContact CG1-CZ 4.19Å
239	A	97.9	Very high	96.2	Very high	17 Å²	17	37.3 Å²	37.3	14%	0.14	18%	0.184	C	C	.	.	H	α-helix	trans	-60.5	-47.7	-178.9	0	0	0	0	0	111.8	L242 E243 F280	A239-L242 PolarHBondContact O-N 3.46Å; A239-E243 PolarHBondContact O-N 2.63Å; A239-F280 HydrophobicContact CB-CB 3.81Å
240	E	98.5	Very high	96.2	Very high	22 Å²	22	40.2 Å²	40.2	10%	0.103	20%	0.199	C	C	.	.	H	α-helix	trans	-66.5	-40.2	-179	-64.7	84.4	168.8	0	0	111.4	F188 R196 K200 G237 V238 L242 E243 I244	F188-E240 HydrophobicContact CD1-CB 4.22Å; F188-E240 HydrophobicContact CE1-CB 4.01Å; R196-E240 HydrophobicContact CB-CG 4Å; R196-E240 WeakPolarHBondContact CB-OE1 3.44Å; R196-E240 IonicContact CZ-OE1 3.27Å; R196-E240 IonicContact NE-OE1 3.83Å; R196-E240 PolarHBondContact NE-OE1 3.01Å; R196-E240 IonicContact NE-OE2 2.95Å; R196-E240 IonicContact NH2-OE1 2.71Å; K200-E240 HydrophobicContact CB-CB 4.11Å; K200-E240 HydrophobicContact CB-CG 4.43Å; K200-E240 HydrophobicContact CD-CB 4Å; K200-E240 HydrophobicContact CD-CG 4.14Å; K200-E240 HydrophobicContact CG-CB 4.08Å; G237-E240 VanDerWaalsContact CA-OE2 3.29Å; G237-E240 WeakPolarHBondContact CA-OE2 3.48Å; V238-E240 PolarHBondContact O-N 3.01Å; E240-L242 VanDerWaalsContact C-N 3.35Å; E240-E243 PolarHBondContact O-N 3.34Å; E240-I244 VanDerWaalsContact O-CG1 3.31Å; E240-I244 WeakPolarHBondContact O-CG1 3.32Å; E240-I244 PolarHBondContact O-N 3.12Å; E240-I244 VanDerWaalsContact O-N 3.14Å
241	L	98.7	Very high	96.2	Very high	0 Å²	0	36.2 Å²	36.2	0%	0	20%	0.203	C	C	.	.	H	α-helix	trans	-64.6	-39.1	174.5	-70.5	-177.9	0	0	0	112	L185 F188 L203 I221 I224 F225 F235 G237 V238 I244 L245	L185-L241 HydrophobicContact CD2-CD2 4.04Å; F188-L241 HydrophobicContact CD1-CD2 3.72Å; F188-L241 HydrophobicContact CD1-CG 3.93Å; F188-L241 HydrophobicContact CD2-CD2 4.31Å; F188-L241 HydrophobicContact CE1-CD2 3.71Å; F188-L241 HydrophobicContact CE1-CG 4.27Å; F188-L241 HydrophobicContact CE2-CD2 4.29Å; F188-L241 HydrophobicContact CG-CD2 4.02Å; F188-L241 HydrophobicContact CG-CG 4.36Å; F188-L241 HydrophobicContact CZ-CD2 3.99Å; L203-L241 HydrophobicContact CD2-CD2 3.93Å; I221-L241 HydrophobicContact CD1-CD2 4.21Å; I221-L241 HydrophobicContact CG1-CD2 4.19Å; I221-L241 HydrophobicContact CG2-CB 4.5Å; I221-L241 HydrophobicContact CG2-CD1 4.43Å; I224-L241 HydrophobicContact CD1-CD1 4.4Å; I224-L241 HydrophobicContact CG2-CD1 4.18Å; F225-L241 HydrophobicContact CE1-CB 3.96Å; F225-L241 HydrophobicContact CE1-CD1 4Å; F225-L241 HydrophobicContact CZ-CB 3.81Å; F235-L241 HydrophobicContact CE1-CD1 3.62Å; F235-L241 HydrophobicContact CE1-CG 4.47Å; F235-L241 HydrophobicContact CZ-CD1 4.12Å; G237-L241 WeakPolarHBondContact O-CG 3.46Å; G237-L241 PolarHBondContact O-N 3.18Å; G237-L241 VanDerWaalsContact O-N 3.13Å; V238-L241 PolarHBondContact O-N 3.39Å; L241-I244 HydrophobicContact CD2-CD1 4.45Å; L241-I244 PolarHBondContact O-N 3.06Å; L241-L245 WeakPolarHBondContact O-CB 3.37Å; L241-L245 VanDerWaalsContact O-CG 3.31Å; L241-L245 WeakPolarHBondContact O-CG 3.19Å; L241-L245 PolarHBondContact O-N 2.91Å
242	L	98.7	Very high	96.2	Very high	0 Å²	0	30.1 Å²	30.1	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-66.9	-38.5	174.9	-74.7	171.9	0	0	0	112	F225 V238 A239 E240 I244 L245 G246 L268 L271 F280 Q283 L284 C287	F225-L242 HydrophobicContact CE2-CD2 3.82Å; F225-L242 HydrophobicContact CE2-CG 4.37Å; F225-L242 HydrophobicContact CZ-CD2 3.88Å; F225-L242 HydrophobicContact CZ-CG 3.91Å; V238-L242 HydrophobicContact CG1-CD1 3.84Å; V238-L242 HydrophobicContact CG1-CG 4.32Å; V238-L242 WeakPolarHBondContact O-CB 3.37Å; V238-L242 WeakPolarHBondContact O-CG 3.35Å; V238-L242 PolarHBondContact O-N 3.21Å; A239-L242 PolarHBondContact O-N 3.46Å; E240-L242 VanDerWaalsContact C-N 3.35Å; L242-I244 VanDerWaalsContact C-N 3.34Å; L242-I244 PolarHBondContact O-N 3.05Å; L242-L245 HydrophobicContact CD2-CD1 4.32Å; L242-L245 CarbonylContact O-C 3.34Å; L242-L245 PolarHBondContact O-N 2.89Å; L242-G246 PolarHBondContact O-N 3.3Å; L242-L268 HydrophobicContact CD2-CD2 3.83Å; L242-L271 HydrophobicContact CD2-CD1 4.14Å; L242-F280 HydrophobicContact CD1-CB 4.11Å; L242-F280 HydrophobicContact CD1-CD2 3.59Å; L242-F280 HydrophobicContact CD1-CE2 4.41Å; L242-F280 HydrophobicContact CD1-CG 4.16Å; L242-Q283 HydrophobicContact CB-CB 3.7Å; L242-Q283 HydrophobicContact CD1-CB 4.46Å; L242-L284 HydrophobicContact CD1-CB 3.91Å; L242-L284 HydrophobicContact CD1-CD1 4.38Å; L242-L284 HydrophobicContact CD2-CD1 4.11Å; L242-C287 PolarHBondContact O-SG 3.41Å
243	E	98.3	Very high	96.4	Very high	91 Å²	91	31.2 Å²	31.2	43%	0.425	19%	0.189	S	C	.	.	H	α-helix	trans	-60.7	-43.7	175.9	-166.3	-174.7	140.3	0	0	111.5	K200 A239 E240 G246 S247 Q283	K200-E243 HydrophobicContact CD-CB 4.23Å; K200-E243 HydrophobicContact CD-CG 4.36Å; K200-E243 WeakPolarHBondContact CD-OE2 3.15Å; K200-E243 VanDerWaalsContact CE-OE1 3.23Å; K200-E243 WeakPolarHBondContact CE-OE1 3.29Å; K200-E243 IonicContact NZ-OE1 3.07Å; K200-E243 PolarHBondContact NZ-OE1 3Å; K200-E243 IonicContact NZ-OE2 3.88Å; K200-E243 PolarHBondContact NZ-OE2 2.79Å; A239-E243 PolarHBondContact O-N 2.63Å; E240-E243 PolarHBondContact O-N 3.34Å; E243-G246 PolarHBondContact O-N 3.49Å; E243-S247 PolarHBondContact O-N 3.24Å; E243-Q283 HydrophobicContact CB-CG 4.46Å
244	I	98.5	Very high	96.6	Very high	3 Å²	3	32.4 Å²	32.4	2%	0.015	20%	0.198	C	C	.	.	H	α-helix	trans	-61.8	-46.3	173.9	-62.4	165.1	0	0	0	110.3	F188 K200 L203 H204 E240 L241 L242 G246 S247 I248	F188-I244 HydrophobicContact CE1-CD1 4.12Å; F188-I244 HydrophobicContact CZ-CD1 3.96Å; K200-I244 HydrophobicContact CB-CD1 4.37Å; K200-I244 HydrophobicContact CG-CD1 3.91Å; K200-I244 HydrophobicContact CG-CG1 3.67Å; L203-I244 HydrophobicContact CB-CD1 4.1Å; L203-I244 HydrophobicContact CD2-CD1 3.76Å; L203-I244 HydrophobicContact CG-CD1 4.19Å; H204-I244 HydrophobicContact CB-CG1 4.48Å; E240-I244 VanDerWaalsContact O-CG1 3.31Å; E240-I244 WeakPolarHBondContact O-CG1 3.32Å; E240-I244 PolarHBondContact O-N 3.12Å; E240-I244 VanDerWaalsContact O-N 3.14Å; L241-I244 HydrophobicContact CD2-CD1 4.45Å; L241-I244 PolarHBondContact O-N 3.06Å; L242-I244 VanDerWaalsContact C-N 3.34Å; L242-I244 PolarHBondContact O-N 3.05Å; I244-G246 VanDerWaalsContact C-N 3.32Å; I244-G246 PolarHBondContact O-N 3.4Å; I244-S247 WeakPolarHBondContact O-CB 3.45Å; I244-S247 PolarHBondContact O-N 3.45Å; I244-I248 HydrophobicContact CG2-CD1 3.74Å; I244-I248 HydrophobicContact CG2-CG1 4.35Å; I244-I248 VanDerWaalsContact O-CG1 3.3Å; I244-I248 WeakPolarHBondContact O-CG1 3.5Å; I244-I248 PolarHBondContact O-N 3.49Å
245	L	98.4	Very high	96.9	Very high	3 Å²	3	35.2 Å²	35.2	2%	0.016	22%	0.221	C	C	.	.	H	α-helix	trans	-62.2	-39.4	179.1	-77.9	167.8	0	0	0	112.1	I221 F225 L241 L242 S247 I248 I249 F263	I221-L245 HydrophobicContact CG2-CD1 3.69Å; I221-L245 HydrophobicContact CG2-CG 4.35Å; F225-L245 HydrophobicContact CD2-CD1 4.4Å; F225-L245 HydrophobicContact CE2-CD1 3.35Å; F225-L245 HydrophobicContact CZ-CD1 3.84Å; L241-L245 WeakPolarHBondContact O-CB 3.37Å; L241-L245 VanDerWaalsContact O-CG 3.31Å; L241-L245 WeakPolarHBondContact O-CG 3.19Å; L241-L245 PolarHBondContact O-N 2.91Å; L242-L245 HydrophobicContact CD2-CD1 4.32Å; L242-L245 CarbonylContact O-C 3.34Å; L242-L245 PolarHBondContact O-N 2.89Å; L245-S247 VanDerWaalsContact C-N 3.3Å; L245-S247 PolarHBondContact O-N 2.94Å; L245-I248 HydrophobicContact CD2-CD1 4.49Å; L245-I248 CarbonylContact O-C 3.58Å; L245-I248 WeakPolarHBondContact O-CA 3.45Å; L245-I248 WeakPolarHBondContact O-CB 3.47Å; L245-I248 PolarHBondContact O-N 3.44Å; L245-I249 HydrophobicContact CB-CD1 4.37Å; L245-I249 WeakPolarHBondContact O-CB 3.5Å; L245-I249 WeakPolarHBondContact O-CD1 3.45Å; L245-I249 WeakPolarHBondContact O-CG1 3.35Å; L245-I249 PolarHBondContact O-N 3.08Å; L245-F263 HydrophobicContact CD1-CE1 4.35Å; L245-F263 HydrophobicContact CD1-CZ 3.7Å; L245-F263 HydrophobicContact CD2-CE1 4.33Å; L245-F263 HydrophobicContact CD2-CZ 4.23Å
246	G	97.8	Very high	97	Very high	0 Å²	0	34.3 Å²	34.3	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-56.2	-45.1	174.9	0	0	0	0	0	111.7	L242 E243 I244 I249 N250 C287	L242-G246 PolarHBondContact O-N 3.3Å; E243-G246 PolarHBondContact O-N 3.49Å; I244-G246 VanDerWaalsContact C-N 3.32Å; I244-G246 PolarHBondContact O-N 3.4Å; G246-I249 PolarHBondContact O-N 3.34Å; G246-N250 WeakPolarHBondContact O-CB 3.35Å; G246-N250 PolarHBondContact O-N 3.13Å; G246-N250 VanDerWaalsContact O-N 3.08Å; G246-C287 PolarHBondContact N-SG 3.06Å
247	S	97	Very high	97.2	Very high	53 Å²	53	38.8 Å²	38.8	37%	0.371	24%	0.236	S	C	.	.	H	α-helix	trans	-63.7	-40.2	173.2	-177.3	0	0	0	0	112.7	H204 E243 I244 L245 G251	H204-S247 PolarHBondContact NE2-OG 3.3Å; E243-S247 PolarHBondContact O-N 3.24Å; I244-S247 WeakPolarHBondContact O-CB 3.45Å; I244-S247 PolarHBondContact O-N 3.45Å; L245-S247 VanDerWaalsContact C-N 3.3Å; L245-S247 PolarHBondContact O-N 2.94Å; S247-G251 PolarHBondContact O-N 3.36Å
248	I	97.6	Very high	97.2	Very high	9 Å²	9	42 Å²	42	5%	0.046	26%	0.263	C	S	.	.	H	α-helix	trans	-65	-42.9	177.8	-69.2	171.4	0	0	0	111.8	Y207 I244 L245 G251 F252	Y207-I248 HydrophobicContact CD1-CD1 3.77Å; Y207-I248 HydrophobicContact CD1-CG1 3.7Å; Y207-I248 HydrophobicContact CD2-CD1 3.69Å; Y207-I248 HydrophobicContact CE1-CB 4.24Å; Y207-I248 HydrophobicContact CE1-CD1 3.71Å; Y207-I248 HydrophobicContact CE1-CG1 3.48Å; Y207-I248 VanDerWaalsContact CE1-CG1 3.48Å; Y207-I248 HydrophobicContact CE1-CG2 3.88Å; Y207-I248 HydrophobicContact CE2-CD1 3.62Å; Y207-I248 HydrophobicContact CE2-CG1 4.33Å; Y207-I248 HydrophobicContact CE2-CG2 4.5Å; Y207-I248 HydrophobicContact CG-CD1 3.77Å; Y207-I248 HydrophobicContact CG-CG1 4.22Å; Y207-I248 VanDerWaalsContact OH-CG2 3.24Å; Y207-I248 WeakPolarHBondContact OH-CG2 3.48Å; I244-I248 HydrophobicContact CG2-CD1 3.74Å; I244-I248 HydrophobicContact CG2-CG1 4.35Å; I244-I248 VanDerWaalsContact O-CG1 3.3Å; I244-I248 WeakPolarHBondContact O-CG1 3.5Å; I244-I248 PolarHBondContact O-N 3.49Å; L245-I248 HydrophobicContact CD2-CD1 4.49Å; L245-I248 CarbonylContact O-C 3.58Å; L245-I248 WeakPolarHBondContact O-CA 3.45Å; L245-I248 WeakPolarHBondContact O-CB 3.47Å; L245-I248 PolarHBondContact O-N 3.44Å; I248-G251 CarbonylContact O-C 3.56Å; I248-G251 WeakPolarHBondContact O-CA 3.24Å; I248-G251 PolarHBondContact O-N 3.08Å; I248-G251 VanDerWaalsContact O-N 3.13Å; I248-F252 HydrophobicContact CG2-CD1 4.33Å; I248-F252 HydrophobicContact CG2-CE1 3.5Å; I248-F252 HydrophobicContact CG2-CZ 3.92Å; I248-F252 WeakPolarHBondContact O-CD1 3.43Å; I248-F252 PolarHBondContact O-N 3.45Å
249	I	98	Very high	97.1	Very high	0 Å²	0	45.9 Å²	45.9	0%	0	28%	0.281	C	S	.	.	H	α-helix	trans	-65.8	-44.8	-178.8	-66.6	157.5	0	0	0	110	L245 G246 G251 F252 L268 C287 Q290 F291	L245-I249 HydrophobicContact CB-CD1 4.37Å; L245-I249 WeakPolarHBondContact O-CB 3.5Å; L245-I249 WeakPolarHBondContact O-CD1 3.45Å; L245-I249 WeakPolarHBondContact O-CG1 3.35Å; L245-I249 PolarHBondContact O-N 3.08Å; G246-I249 PolarHBondContact O-N 3.34Å; I249-G251 PolarHBondContact O-N 2.77Å; I249-F252 HydrophobicContact CB-CD2 4.27Å; I249-F252 HydrophobicContact CB-CE2 4.12Å; I249-F252 HydrophobicContact CG1-CD2 4.38Å; I249-F252 HydrophobicContact CG1-CE2 3.74Å; I249-F252 HydrophobicContact CG1-CZ 4.18Å; I249-F252 HydrophobicContact CG2-CD2 4.16Å; I249-F252 HydrophobicContact CG2-CE2 4.28Å; I249-F252 WeakPolarHBondContact O-CB 2.96Å; I249-F252 PolarHBondContact O-N 3.34Å; I249-L268 HydrophobicContact CD1-CD1 4.38Å; I249-C287 HydrophobicContact CD1-CB 3.84Å; I249-Q290 HydrophobicContact CB-CB 4.41Å; I249-Q290 HydrophobicContact CG2-CB 3.8Å; I249-F291 HydrophobicContact CD1-CD2 3.81Å; I249-F291 HydrophobicContact CD1-CE2 3.43Å; I249-F291 VanDerWaalsContact CD1-CE2 3.43Å; I249-F291 HydrophobicContact CD1-CZ 4.35Å; I249-F291 HydrophobicContact CG1-CD2 4.2Å; I249-F291 HydrophobicContact CG1-CE2 3.65Å; I249-F291 HydrophobicContact CG1-CZ 4.11Å; I249-F291 HydrophobicContact CG2-CD1 4.37Å; I249-F291 HydrophobicContact CG2-CD2 3.8Å; I249-F291 HydrophobicContact CG2-CE2 3.98Å; I249-F291 HydrophobicContact CG2-CG 4Å; I249-F291 HydrophobicContact CG2-CZ 4.35Å
250	N	96.3	Very high	97.1	Very high	75 Å²	75	45.7 Å²	45.7	40%	0.401	28%	0.277	S	S	.	.	H	α-helix	trans	-55.7	-36.1	172.6	-168.9	-32.3	0	0	0	111.1	G246 F252 Q290 K294	G246-N250 WeakPolarHBondContact O-CB 3.35Å; G246-N250 PolarHBondContact O-N 3.13Å; G246-N250 VanDerWaalsContact O-N 3.08Å; N250-F252 VanDerWaalsContact C-N 3.33Å; N250-F252 PolarHBondContact O-N 2.92Å; N250-Q290 VanDerWaalsContact CG-OE1 3.23Å; N250-Q290 PolarHBondContact ND2-OE1 2.89Å; N250-K294 WeakPolarHBondContact O-CE 2.93Å; N250-K294 PolarHBondContact O-NZ 3.35Å
251	G	95.4	Very high	97.1	Very high	65 Å²	65	47.9 Å²	47.9	67%	0.67	29%	0.286	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78.2	-0.1	175.9	0	0	0	0	0	116.6	S247 I248 I249	S247-G251 PolarHBondContact O-N 3.36Å; I248-G251 CarbonylContact O-C 3.56Å; I248-G251 WeakPolarHBondContact O-CA 3.24Å; I248-G251 PolarHBondContact O-N 3.08Å; I248-G251 VanDerWaalsContact O-N 3.13Å; I249-G251 PolarHBondContact O-N 2.77Å
252	F	96.2	Very high	97	Very high	19 Å²	19	54 Å²	54	8%	0.083	32%	0.315	C	S	.	.	P	Polyproline II helix	trans	-67.2	135.8	-178.2	-72.7	-23	0	0	0	112.8	I248 I249 N250 L256 H260 F291	I248-F252 HydrophobicContact CG2-CD1 4.33Å; I248-F252 HydrophobicContact CG2-CE1 3.5Å; I248-F252 HydrophobicContact CG2-CZ 3.92Å; I248-F252 WeakPolarHBondContact O-CD1 3.43Å; I248-F252 PolarHBondContact O-N 3.45Å; I249-F252 HydrophobicContact CB-CD2 4.27Å; I249-F252 HydrophobicContact CB-CE2 4.12Å; I249-F252 HydrophobicContact CG1-CD2 4.38Å; I249-F252 HydrophobicContact CG1-CE2 3.74Å; I249-F252 HydrophobicContact CG1-CZ 4.18Å; I249-F252 HydrophobicContact CG2-CD2 4.16Å; I249-F252 HydrophobicContact CG2-CE2 4.28Å; I249-F252 WeakPolarHBondContact O-CB 2.96Å; I249-F252 PolarHBondContact O-N 3.34Å; N250-F252 VanDerWaalsContact C-N 3.33Å; N250-F252 PolarHBondContact O-N 2.92Å; F252-L256 HydrophobicContact CB-CD2 3.73Å; F252-L256 HydrophobicContact CD2-CD2 3.83Å; F252-L256 HydrophobicContact CG-CD2 4.2Å; F252-H260 AromaticContact CD1-CE1 3.64Å; F252-H260 HydrophobicContact CD2-CB 4.32Å; F252-H260 AromaticContact CD2-ND1 3.74Å; F252-H260 AromaticContact CE1-CD2 3.99Å; F252-H260 AromaticContact CE1-CE1 3.61Å; F252-H260 AromaticContact CE1-NE2 3.56Å; F252-H260 HydrophobicContact CE2-CB 3.91Å; F252-H260 AromaticContact CE2-CD2 3.92Å; F252-H260 AromaticContact CE2-CG 3.65Å; F252-H260 AromaticContact CE2-ND1 3.81Å; F252-H260 AromaticContact CG-CE1 3.94Å; F252-H260 AromaticContact CG-ND1 3.87Å; F252-H260 HydrophobicContact CZ-CB 4.45Å; F252-H260 AromaticContact CZ-CD2 3.58Å; F252-H260 AromaticContact CZ-CE1 3.89Å; F252-H260 AromaticContact CZ-CG 3.81Å; F252-H260 AromaticContact CZ-ND1 3.99Å; F252-H260 AromaticContact CZ-NE2 3.68Å; F252-F291 HydrophobicContact CD2-CE1 4.41Å; F252-F291 HydrophobicContact CE2-CE1 4.13Å; F252-F291 AromaticContact CE2-CZ 3.86Å; F252-F291 HydrophobicContact CE2-CZ 3.86Å
253	A	95.2	Very high	97	Very high	81 Å²	81	54.7 Å²	54.7	67%	0.669	32%	0.318	S	S	*	.	P	Polyproline II helix	trans	-72	146.3	171	0	0	0	0	0	110.8	P255	A253-P255 CarbonylContact O-C 3.32Å
254	L	95.1	Very high	97	Very high	112 Å²	112	50.4 Å²	50.4	59%	0.586	30%	0.298	S	S	*	.	S	Bend	trans	-96.5	141.6	172.7	-59	-178.5	0	0	0	110	L256 K294	L254-L256 HydrophobicContact CD2-CD2 4.36Å; L254-L256 HydrophobicContact CD2-CG 4.21Å; L254-K294 HydrophobicContact CD2-CB 4.02Å; L254-K294 HydrophobicContact CD2-CD 4.08Å; L254-K294 VanDerWaalsContact CD2-O 3.23Å; L254-K294 WeakPolarHBondContact CD2-O 3.48Å
255	P	96.1	Very high	96.9	Very high	123 Å²	123	52.9 Å²	52.9	80%	0.799	31%	0.313	S	S	*	.	S	Bend	cis	-71.9	150.4	-3	30.8	-35.8	0	0	0	113	A253 K257	A253-P255 CarbonylContact O-C 3.32Å; P255-K257 PolarHBondContact O-N 2.67Å
256	L	97.2	Very high	96.8	Very high	13 Å²	13	59.5 Å²	59.5	7%	0.068	34%	0.342	C	S	.	.	P	Polyproline II helix	trans	-60.5	133.1	176.6	-70.4	179.4	0	0	0	111.4	F252 L254 K261 F291 K294 D295 L298	F252-L256 HydrophobicContact CB-CD2 3.73Å; F252-L256 HydrophobicContact CD2-CD2 3.83Å; F252-L256 HydrophobicContact CG-CD2 4.2Å; L254-L256 HydrophobicContact CD2-CD2 4.36Å; L254-L256 HydrophobicContact CD2-CG 4.21Å; L256-K261 HydrophobicContact CB-CG 4.38Å; L256-F291 HydrophobicContact CD1-CD1 4.01Å; L256-F291 HydrophobicContact CD1-CE1 4.31Å; L256-K294 HydrophobicContact CD1-CB 4.08Å; L256-K294 HydrophobicContact CD2-CB 4.22Å; L256-K294 HydrophobicContact CG-CB 4.32Å; L256-D295 HydrophobicContact CD1-CB 3.63Å; L256-D295 HydrophobicContact CG-CB 4.34Å; L256-L298 HydrophobicContact CD1-CD1 3.76Å
257	K	96.6	Very high	96.9	Very high	125 Å²	125	59.8 Å²	59.8	54%	0.543	34%	0.344	S	S	.	.	P	Polyproline II helix	trans	-65.4	149.9	174.1	-61.7	-176.6	179.6	-178.3	0	111.4	P255 E259 H260 K261	P255-K257 PolarHBondContact O-N 2.67Å; K257-E259 HydrophobicContact CB-CG 3.88Å; K257-E259 HydrophobicContact CD-CG 4.4Å; K257-E259 PolarHBondContact O-N 3.36Å; K257-H260 WeakPolarHBondContact O-CB 3.45Å; K257-H260 PolarHBondContact O-N 3.21Å; K257-K261 PolarHBondContact O-N 3.44Å
258	A	96.5	Very high	96.9	Very high	69 Å²	69	57.3 Å²	57.3	57%	0.57	33%	0.326	S	S	*	.	H	α-helix	trans	-55.6	-37.3	176.6	0	0	0	0	0	113	H260 K261 Q262	A258-H260 VanDerWaalsContact C-N 3.28Å; A258-H260 PolarHBondContact O-N 2.95Å; A258-K261 PolarHBondContact O-N 2.89Å; A258-Q262 WeakPolarHBondContact O-CG 3.16Å; A258-Q262 PolarHBondContact O-N 2.98Å
259	E	96.1	Very high	97	Very high	84 Å²	84	57 Å²	57	39%	0.393	33%	0.325	S	S	.	.	H	α-helix	trans	-59.5	-36.4	176	60.1	171.3	-175.2	0	0	112.8	R218 K257 F263	R218-E259 IonicContact CZ-OE1 2.76Å; R218-E259 IonicContact NH2-OE1 2.83Å; R218-E259 PolarHBondContact NH2-OE1 2.97Å; K257-E259 HydrophobicContact CB-CG 3.88Å; K257-E259 HydrophobicContact CD-CG 4.4Å; K257-E259 PolarHBondContact O-N 3.36Å; E259-F263 WeakPolarHBondContact O-CB 3.33Å; E259-F263 PolarHBondContact O-N 3.5Å
260	H	97.4	Very high	97	Very high	13 Å²	13	57.4 Å²	57.4	6%	0.06	33%	0.327	C	S	.	.	H	α-helix	trans	-72.9	-40.2	179.4	-54.1	155.9	0	0	0	111.1	F252 K257 A258 Q262 F263 L264 F291	F252-H260 AromaticContact CD1-CE1 3.64Å; F252-H260 HydrophobicContact CD2-CB 4.32Å; F252-H260 AromaticContact CD2-ND1 3.74Å; F252-H260 AromaticContact CE1-CD2 3.99Å; F252-H260 AromaticContact CE1-CE1 3.61Å; F252-H260 AromaticContact CE1-NE2 3.56Å; F252-H260 HydrophobicContact CE2-CB 3.91Å; F252-H260 AromaticContact CE2-CD2 3.92Å; F252-H260 AromaticContact CE2-CG 3.65Å; F252-H260 AromaticContact CE2-ND1 3.81Å; F252-H260 AromaticContact CG-CE1 3.94Å; F252-H260 AromaticContact CG-ND1 3.87Å; F252-H260 HydrophobicContact CZ-CB 4.45Å; F252-H260 AromaticContact CZ-CD2 3.58Å; F252-H260 AromaticContact CZ-CE1 3.89Å; F252-H260 AromaticContact CZ-CG 3.81Å; F252-H260 AromaticContact CZ-ND1 3.99Å; F252-H260 AromaticContact CZ-NE2 3.68Å; K257-H260 WeakPolarHBondContact O-CB 3.45Å; K257-H260 PolarHBondContact O-N 3.21Å; A258-H260 VanDerWaalsContact C-N 3.28Å; A258-H260 PolarHBondContact O-N 2.95Å; H260-Q262 VanDerWaalsContact C-N 3.34Å; H260-F263 WeakPolarHBondContact O-CB 3.38Å; H260-F263 PolarHBondContact O-N 3.4Å; H260-L264 PolarHBondContact O-N 2.76Å; H260-F291 HydrophobicContact CB-CE1 4Å; H260-F291 HydrophobicContact CB-CZ 4.27Å; H260-F291 WeakPolarHBondContact O-CZ 3.42Å
261	K	97.6	Very high	97	Very high	68 Å²	68	53.9 Å²	53.9	30%	0.296	31%	0.308	S	S	.	.	H	α-helix	trans	-63.8	-40.5	174.9	-61	-172.4	174.8	-156.1	0	111.5	L256 K257 A258 L264 V265 D295 L298	L256-K261 HydrophobicContact CB-CG 4.38Å; K257-K261 PolarHBondContact O-N 3.44Å; A258-K261 PolarHBondContact O-N 2.89Å; K261-L264 PolarHBondContact O-N 3.45Å; K261-V265 PolarHBondContact O-N 3.34Å; K261-D295 WeakPolarHBondContact CE-OD2 3.46Å; K261-D295 IonicContact NZ-OD2 3Å; K261-D295 PolarHBondContact NZ-OD2 3.4Å; K261-L298 HydrophobicContact CD-CD2 4.07Å; K261-L298 HydrophobicContact CG-CD1 4.33Å; K261-L298 HydrophobicContact CG-CD2 4.15Å
262	Q	97.2	Very high	97.2	Very high	129 Å²	129	50.8 Å²	50.8	60%	0.603	28%	0.276	S	S	*	.	H	α-helix	trans	-64.9	-41.9	174.2	-73.6	-180	-1.3	0	0	111.7	A258 H260 L264 V265 K266	A258-Q262 WeakPolarHBondContact O-CG 3.16Å; A258-Q262 PolarHBondContact O-N 2.98Å; H260-Q262 VanDerWaalsContact C-N 3.34Å; Q262-L264 PolarHBondContact O-N 2.89Å; Q262-V265 PolarHBondContact O-N 2.84Å; Q262-K266 WeakPolarHBondContact O-CB 3.41Å; Q262-K266 WeakPolarHBondContact O-CG 3.19Å; Q262-K266 PolarHBondContact O-N 2.98Å
263	F	97.9	Very high	97.2	Very high	14 Å²	14	52.6 Å²	52.6	6%	0.061	29%	0.289	C	S	.	.	H	α-helix	trans	-57	-47.1	175.6	172.6	-114.4	0	0	0	112.1	N222 F225 L245 E259 H260 V265 V267 L268 F291	N222-F263 WeakPolarHBondContact OD1-CD2 3.3Å; N222-F263 WeakPolarHBondContact OD1-CE2 3.49Å; F225-F263 HydrophobicContact CD2-CE2 4.27Å; F225-F263 HydrophobicContact CD2-CZ 4.46Å; F225-F263 HydrophobicContact CE2-CZ 4.41Å; L245-F263 HydrophobicContact CD1-CE1 4.35Å; L245-F263 HydrophobicContact CD1-CZ 3.7Å; L245-F263 HydrophobicContact CD2-CE1 4.33Å; L245-F263 HydrophobicContact CD2-CZ 4.23Å; E259-F263 WeakPolarHBondContact O-CB 3.33Å; E259-F263 PolarHBondContact O-N 3.5Å; H260-F263 WeakPolarHBondContact O-CB 3.38Å; H260-F263 PolarHBondContact O-N 3.4Å; F263-V265 PolarHBondContact O-N 2.9Å; F263-V267 HydrophobicContact CD2-CB 3.63Å; F263-V267 HydrophobicContact CD2-CG1 4.11Å; F263-V267 HydrophobicContact CD2-CG2 3.77Å; F263-V267 HydrophobicContact CE2-CB 3.71Å; F263-V267 HydrophobicContact CE2-CG1 3.69Å; F263-V267 HydrophobicContact CE2-CG2 4.22Å; F263-V267 WeakPolarHBondContact O-CA 3.42Å; F263-V267 VanDerWaalsContact O-CB 3.28Å; F263-V267 WeakPolarHBondContact O-CB 3.43Å; F263-V267 PolarHBondContact O-N 2.94Å; F263-L268 HydrophobicContact CD1-CD1 4.22Å; F263-L268 HydrophobicContact CD1-CG 4.18Å; F263-L268 HydrophobicContact CE1-CD1 3.74Å; F263-L268 HydrophobicContact CE1-CD2 3.77Å; F263-L268 HydrophobicContact CE1-CG 3.65Å; F263-L268 HydrophobicContact CE2-CD2 4.31Å; F263-L268 HydrophobicContact CE2-CG 4.46Å; F263-L268 HydrophobicContact CZ-CD1 4.36Å; F263-L268 HydrophobicContact CZ-CD2 3.52Å; F263-L268 HydrophobicContact CZ-CG 3.8Å; F263-L268 PolarHBondContact O-N 3.38Å; F263-L268 VanDerWaalsContact O-N 3.11Å; F263-F291 HydrophobicContact CD1-CE2 4.04Å; F263-F291 HydrophobicContact CD1-CZ 4.02Å; F263-F291 HydrophobicContact CE1-CE2 4.32Å
264	L	98.2	Very high	97.2	Very high	0 Å²	0	48.8 Å²	48.8	0%	0	26%	0.257	C	S	.	.	I	π-helix	trans	-53.9	-55.8	174.5	174	63.1	0	0	0	111.7	H260 K261 Q262 L268 I269 I288 F291 L298 V302	H260-L264 PolarHBondContact O-N 2.76Å; K261-L264 PolarHBondContact O-N 3.45Å; Q262-L264 PolarHBondContact O-N 2.89Å; L264-L268 HydrophobicContact CD1-CB 4.28Å; L264-L268 HydrophobicContact CD1-CD1 4.1Å; L264-L268 PolarHBondContact O-N 3.29Å; L264-I269 WeakPolarHBondContact O-CG1 3.2Å; L264-I269 PolarHBondContact O-N 3.29Å; L264-I288 HydrophobicContact CD1-CD1 3.44Å; L264-I288 VanDerWaalsContact CD1-CD1 3.44Å; L264-F291 HydrophobicContact CB-CD1 4.37Å; L264-F291 HydrophobicContact CB-CD2 4.3Å; L264-F291 HydrophobicContact CB-CE1 4.3Å; L264-F291 HydrophobicContact CB-CE2 4.23Å; L264-F291 HydrophobicContact CB-CG 4.37Å; L264-F291 HydrophobicContact CB-CZ 4.23Å; L264-F291 HydrophobicContact CD1-CB 4.21Å; L264-F291 HydrophobicContact CD1-CD2 3.93Å; L264-F291 HydrophobicContact CD1-CG 4.11Å; L264-F291 HydrophobicContact CD2-CB 4.02Å; L264-F291 HydrophobicContact CD2-CD1 4.14Å; L264-F291 HydrophobicContact CD2-CG 4.03Å; L264-F291 HydrophobicContact CG-CG 4.4Å; L264-L298 HydrophobicContact CD2-CB 4.01Å; L264-L298 HydrophobicContact CD2-CD1 3.79Å; L264-L298 HydrophobicContact CD2-CG 4.36Å; L264-V302 HydrophobicContact CD1-CG2 4.01Å; L264-V302 HydrophobicContact CD2-CG2 3.74Å; L264-V302 HydrophobicContact CG-CG2 4.06Å
265	V	97.5	Very high	97	Very high	56 Å²	56	53.2 Å²	53.2	34%	0.339	27%	0.266	S	S	.	.	I	π-helix	trans	-75.9	-33.3	-171.4	177.8	0	0	0	0	113.4	K261 Q262 F263 I269	K261-V265 PolarHBondContact O-N 3.34Å; Q262-V265 PolarHBondContact O-N 2.84Å; F263-V265 PolarHBondContact O-N 2.9Å; V265-I269 HydrophobicContact CG2-CD1 4.43Å
266	K	97	Very high	96.9	Very high	141 Å²	141	48.9 Å²	48.9	61%	0.613	24%	0.239	S	C	*	.	I	π-helix	trans	-99.4	-15.8	-172.5	-60.1	-63.4	-173	178.4	0	114	Q262	Q262-K266 WeakPolarHBondContact O-CB 3.41Å; Q262-K266 WeakPolarHBondContact O-CG 3.19Å; Q262-K266 PolarHBondContact O-N 2.98Å
267	V	98	Very high	96.8	Very high	7 Å²	7	48.2 Å²	48.2	4%	0.042	24%	0.236	C	C	.	.	I	π-helix	trans	-125.1	-58.1	-177.7	-169.9	0	0	0	0	111.3	F225 L226 F263 P270 L271	F225-V267 HydrophobicContact CB-CG1 3.45Å; F225-V267 VanDerWaalsContact CB-CG1 3.45Å; F225-V267 HydrophobicContact CD2-CG1 3.74Å; F225-V267 HydrophobicContact CG-CG1 4.12Å; L226-V267 HydrophobicContact CD2-CG2 4.16Å; L226-V267 HydrophobicContact CG-CG2 4.37Å; F263-V267 HydrophobicContact CD2-CB 3.63Å; F263-V267 HydrophobicContact CD2-CG1 4.11Å; F263-V267 HydrophobicContact CD2-CG2 3.77Å; F263-V267 HydrophobicContact CE2-CB 3.71Å; F263-V267 HydrophobicContact CE2-CG1 3.69Å; F263-V267 HydrophobicContact CE2-CG2 4.22Å; F263-V267 WeakPolarHBondContact O-CA 3.42Å; F263-V267 VanDerWaalsContact O-CB 3.28Å; F263-V267 WeakPolarHBondContact O-CB 3.43Å; F263-V267 PolarHBondContact O-N 2.94Å; V267-P270 WeakPolarHBondContact O-CD 3.47Å; V267-L271 WeakPolarHBondContact O-CG 3.1Å; V267-L271 PolarHBondContact O-N 3.32Å
268	L	98.5	Very high	96.7	Very high	0 Å²	0	44.1 Å²	44.1	0%	0	22%	0.223	C	C	.	.	I	π-helix	trans	-65.3	-47.5	-176.3	-63.9	-175.4	0	0	0	112.9	L242 I249 F263 L264 L271 H272 L284 C287 I288 F291	L242-L268 HydrophobicContact CD2-CD2 3.83Å; I249-L268 HydrophobicContact CD1-CD1 4.38Å; F263-L268 HydrophobicContact CD1-CD1 4.22Å; F263-L268 HydrophobicContact CD1-CG 4.18Å; F263-L268 HydrophobicContact CE1-CD1 3.74Å; F263-L268 HydrophobicContact CE1-CD2 3.77Å; F263-L268 HydrophobicContact CE1-CG 3.65Å; F263-L268 HydrophobicContact CE2-CD2 4.31Å; F263-L268 HydrophobicContact CE2-CG 4.46Å; F263-L268 HydrophobicContact CZ-CD1 4.36Å; F263-L268 HydrophobicContact CZ-CD2 3.52Å; F263-L268 HydrophobicContact CZ-CG 3.8Å; F263-L268 PolarHBondContact O-N 3.38Å; F263-L268 VanDerWaalsContact O-N 3.11Å; L264-L268 HydrophobicContact CD1-CB 4.28Å; L264-L268 HydrophobicContact CD1-CD1 4.1Å; L264-L268 PolarHBondContact O-N 3.29Å; L268-L271 HydrophobicContact CD2-CD1 4.09Å; L268-L271 WeakPolarHBondContact O-CB 3.5Å; L268-L271 PolarHBondContact O-N 3.1Å; L268-H272 PolarHBondContact O-CE1 3.22Å; L268-H272 PolarHBondContact O-ND1 3.17Å; L268-L284 HydrophobicContact CB-CD1 4.16Å; L268-L284 HydrophobicContact CD2-CD1 3.94Å; L268-C287 HydrophobicContact CD1-CB 4.05Å; L268-I288 HydrophobicContact CB-CD1 3.84Å; L268-I288 HydrophobicContact CD1-CD1 4.29Å; L268-F291 HydrophobicContact CD1-CD2 3.78Å; L268-F291 HydrophobicContact CD1-CE2 3.57Å
269	I	98.3	Very high	96.6	Very high	4 Å²	4	44.1 Å²	44.1	2%	0.021	21%	0.213	C	C	.	.	H	α-helix	trans	-61.3	-47.1	179	-63.1	175.7	0	0	0	111.4	L264 V265 L271 H272 V302 F309	L264-I269 WeakPolarHBondContact O-CG1 3.2Å; L264-I269 PolarHBondContact O-N 3.29Å; V265-I269 HydrophobicContact CG2-CD1 4.43Å; I269-L271 VanDerWaalsContact C-N 3.27Å; I269-L271 PolarHBondContact O-N 3.46Å; I269-H272 PolarHBondContact O-N 3.31Å; I269-H272 PolarHBondContact O-ND1 3.04Å; I269-V302 HydrophobicContact CD1-CG2 4.16Å; I269-F309 HydrophobicContact CG2-CD2 3.85Å; I269-F309 HydrophobicContact CG2-CE2 3.85Å
270	P	97.9	Very high	96.6	Very high	8 Å²	8	40.4 Å²	40.4	5%	0.052	20%	0.195	C	C	.	.	H	α-helix	trans	-60.9	-25	175	-29.7	38.6	0	0	0	116	V229 V267 H272 T273 F309	V229-P270 HydrophobicContact CG1-CB 4.1Å; V267-P270 WeakPolarHBondContact O-CD 3.47Å; P270-H272 PolarHBondContact O-N 3.3Å; P270-H272 VanDerWaalsContact O-N 3.08Å; P270-T273 PolarHBondContact O-N 3.23Å; P270-T273 PolarHBondContact O-OG1 3.38Å; P270-F309 HydrophobicContact CG-CE2 4.36Å
271	L	98.1	Very high	96.6	Very high	0 Å²	0	40.7 Å²	40.7	0%	0	20%	0.197	C	C	.	.	H	α-helix	trans	-57.8	-25.1	177.2	-78	168	0	0	0	113	F225 F228 V229 L242 V267 L268 I269 T273 V274 F280 L284	F225-L271 HydrophobicContact CB-CD2 4.46Å; F225-L271 HydrophobicContact CD2-CD1 3.94Å; F225-L271 HydrophobicContact CE2-CD1 4.13Å; F225-L271 HydrophobicContact CG-CD1 4.27Å; F225-L271 HydrophobicContact CG-CD2 4.49Å; F228-L271 HydrophobicContact CD1-CD2 3.61Å; F228-L271 HydrophobicContact CE1-CD2 3.82Å; V229-L271 HydrophobicContact CG2-CD2 3.48Å; V229-L271 VanDerWaalsContact CG2-CD2 3.48Å; V229-L271 HydrophobicContact CG2-CG 4.05Å; L242-L271 HydrophobicContact CD2-CD1 4.14Å; V267-L271 WeakPolarHBondContact O-CG 3.1Å; V267-L271 PolarHBondContact O-N 3.32Å; L268-L271 HydrophobicContact CD2-CD1 4.09Å; L268-L271 WeakPolarHBondContact O-CB 3.5Å; L268-L271 PolarHBondContact O-N 3.1Å; I269-L271 VanDerWaalsContact C-N 3.27Å; I269-L271 PolarHBondContact O-N 3.46Å; L271-T273 PolarHBondContact O-N 2.83Å; L271-V274 WeakPolarHBondContact O-CG2 3.29Å; L271-V274 PolarHBondContact O-N 2.92Å; L271-F280 HydrophobicContact CB-CE2 4.46Å; L271-L284 HydrophobicContact CB-CD1 4.28Å; L271-L284 HydrophobicContact CB-CD2 3.7Å; L271-L284 HydrophobicContact CD1-CD1 4.07Å
272	H	98.1	Very high	96.6	Very high	0 Å²	0	40.6 Å²	40.6	0%	0	21%	0.209	C	C	.	.	T	Hydrogen-bonded Turn	trans	-65.6	-16.6	176.6	-56.3	83	0	0	0	113.5	L268 I269 P270 L284 K317 F321 E324	L268-H272 PolarHBondContact O-CE1 3.22Å; L268-H272 PolarHBondContact O-ND1 3.17Å; I269-H272 PolarHBondContact O-N 3.31Å; I269-H272 PolarHBondContact O-ND1 3.04Å; P270-H272 PolarHBondContact O-N 3.3Å; P270-H272 VanDerWaalsContact O-N 3.08Å; H272-L284 VanDerWaalsContact CE1-CD2 3.44Å; H272-L284 WeakPolarHBondContact CE1-CD2 3.18Å; H272-L284 VanDerWaalsContact NE2-CD2 3.29Å; H272-L284 WeakPolarHBondContact NE2-CD2 3.42Å; H272-L284 WeakPolarHBondContact NE2-CG 3.49Å; H272-K317 WeakPolarHBondContact O-CE 3.32Å; H272-K317 PolarHBondContact O-NZ 3.3Å; H272-F321 HydrophobicContact CB-CE1 4.47Å; H272-F321 HydrophobicContact CB-CE2 4.08Å; H272-F321 HydrophobicContact CB-CZ 3.63Å; H272-E324 IonicContact CD2-OE1 3.83Å; H272-E324 IonicContact CD2-OE2 3.9Å; H272-E324 PolarHBondContact CD2-OE2 3.3Å; H272-E324 IonicContact CE1-OE1 3.91Å; H272-E324 IonicContact NE2-OE1 2.84Å; H272-E324 PolarHBondContact NE2-OE1 2.9Å; H272-E324 VanDerWaalsContact NE2-OE1 3.1Å; H272-E324 IonicContact NE2-OE2 3.24Å; H272-E324 PolarHBondContact NE2-OE2 3.37Å
273	T	96.3	Very high	96.7	Very high	58 Å²	58	37.1 Å²	37.1	36%	0.356	19%	0.192	S	C	.	.	T	Hydrogen-bonded Turn	trans	-78.8	-28.2	-176.8	66.8	0	0	0	0	113.3	P270 L271 F309 K317	P270-T273 PolarHBondContact O-N 3.23Å; P270-T273 PolarHBondContact O-OG1 3.38Å; L271-T273 PolarHBondContact O-N 2.83Å; T273-F309 HydrophobicContact CG2-CB 3.91Å; T273-F309 HydrophobicContact CG2-CD1 3.38Å; T273-F309 HydrophobicContact CG2-CD2 3.9Å; T273-F309 HydrophobicContact CG2-CE1 3.75Å; T273-F309 HydrophobicContact CG2-CE2 4.22Å; T273-F309 HydrophobicContact CG2-CG 3.47Å; T273-F309 VanDerWaalsContact CG2-CG 3.47Å; T273-F309 HydrophobicContact CG2-CZ 4.15Å; T273-K317 PolarHBondContact O-NZ 3.13Å; T273-K317 VanDerWaalsContact O-NZ 3.15Å
274	V	94.8	Very high	96.7	Very high	0 Å²	0	36.5 Å²	36.5	0%	0	19%	0.189	C	C	.	.	S	Bend	trans	-64.5	154.5	-174.3	-61.7	0	0	0	0	112.5	F228 V229 L271 F280 K317	F228-V274 HydrophobicContact CD1-CG1 4.4Å; F228-V274 HydrophobicContact CE1-CB 4.22Å; F228-V274 HydrophobicContact CE1-CG1 3.9Å; F228-V274 HydrophobicContact CE1-CG2 3.74Å; F228-V274 HydrophobicContact CZ-CB 4.18Å; F228-V274 HydrophobicContact CZ-CG1 4.19Å; F228-V274 HydrophobicContact CZ-CG2 3.86Å; V229-V274 HydrophobicContact CB-CG1 4.49Å; V229-V274 HydrophobicContact CG2-CG1 4.18Å; L271-V274 WeakPolarHBondContact O-CG2 3.29Å; L271-V274 PolarHBondContact O-N 2.92Å; V274-F280 HydrophobicContact CG2-CE1 4.11Å; V274-F280 HydrophobicContact CG2-CE2 4.48Å; V274-F280 HydrophobicContact CG2-CZ 3.45Å; V274-F280 VanDerWaalsContact CG2-CZ 3.45Å; V274-K317 PolarHBondContact O-NZ 3.25Å
275	R	92.4	Very high	96.8	Very high	205 Å²	205	36.5 Å²	36.5	77%	0.774	19%	0.189	S	C	*	.	G	3₁₀ helix	trans	-68.2	-43.5	-173.7	-59.2	-179.5	-165.2	-167.8	1.6	112.4	E233 L277	E233-R275 IonicContact OE2-NE 2.72Å; R275-L277 PolarHBondContact O-N 3.33Å
276	S	92.7	Very high	96.8	Very high	32 Å²	32	38.4 Å²	38.4	22%	0.224	19%	0.191	C	C	.	.	G	3₁₀ helix	trans	-78.2	26.2	-177.7	51.5	0	0	0	0	114.3	S278 L279 F280	S276-S278 PolarHBondContact O-N 3.02Å; S276-L279 PolarHBondContact O-N 3.18Å; S276-F280 WeakPolarHBondContact O-CE1 3.49Å
277	L	95.6	Very high	96.9	Very high	0 Å²	0	31.7 Å²	31.7	0%	0	16%	0.162	C	C	.	.	G	3₁₀ helix	trans	-55.7	-35.2	-178.3	179.7	61.3	0	0	0	112.2	R275 L279 F280 H281 L284 M320 F321	R275-L277 PolarHBondContact O-N 3.33Å; L277-L279 PolarHBondContact O-N 3.42Å; L277-L279 VanDerWaalsContact O-N 3.12Å; L277-F280 HydrophobicContact CD1-CD2 4.32Å; L277-F280 HydrophobicContact CD1-CE2 3.67Å; L277-F280 HydrophobicContact CD1-CZ 4.14Å; L277-F280 PolarHBondContact O-N 2.96Å; L277-H281 HydrophobicContact CD1-CB 4.3Å; L277-H281 HydrophobicContact CG-CB 4.2Å; L277-H281 WeakPolarHBondContact O-CA 3.25Å; L277-H281 VanDerWaalsContact O-CB 3.3Å; L277-H281 WeakPolarHBondContact O-CB 3.44Å; L277-H281 PolarHBondContact O-N 3.5Å; L277-L284 HydrophobicContact CD1-CD2 3.96Å; L277-M320 HydrophobicContact CB-CE 4.3Å; L277-M320 HydrophobicContact CD2-CE 4.12Å; L277-M320 HydrophobicContact CG-CE 3.75Å; L277-F321 HydrophobicContact CD2-CD2 4.31Å; L277-F321 HydrophobicContact CD2-CE2 3.76Å
278	S	94.6	Very high	96.9	Very high	39 Å²	39	31.4 Å²	31.4	27%	0.273	16%	0.16	S	C	.	.	G	3₁₀ helix	trans	-54.6	-30.2	-178.9	49.5	0	0	0	0	113.9	E138 S276 F280 M320	E138-S278 WeakPolarHBondContact OE1-CB 3.34Å; E138-S278 PolarHBondContact OE1-OG 3.15Å; S276-S278 PolarHBondContact O-N 3.02Å; S278-F280 VanDerWaalsContact C-N 3.33Å; S278-F280 PolarHBondContact O-N 2.88Å; S278-M320 VanDerWaalsContact CA-CE 3.43Å
279	L	93.7	Very high	96.9	Very high	69 Å²	69	32 Å²	32	36%	0.361	16%	0.164	S	C	.	.	G	3₁₀ helix	trans	-72.6	-23.8	-176.7	-55.7	177.7	0	0	0	114	P137 E138 S276 L277	P137-L279 HydrophobicContact CB-CD1 3.53Å; P137-L279 HydrophobicContact CB-CD2 3.99Å; P137-L279 HydrophobicContact CB-CG 4.42Å; P137-L279 HydrophobicContact CG-CD1 3.58Å; E138-L279 HydrophobicContact CG-CD2 3.78Å; S276-L279 PolarHBondContact O-N 3.18Å; L277-L279 PolarHBondContact O-N 3.42Å; L277-L279 VanDerWaalsContact O-N 3.12Å
280	F	96.8	Very high	96.9	Very high	5 Å²	5	32.4 Å²	32.4	2%	0.022	17%	0.166	C	C	.	.	T	Hydrogen-bonded Turn	trans	-139.7	8.7	-172.4	60.6	-99	0	0	0	114.1	F228 V238 A239 L242 L271 V274 S276 L277 S278 A282 Q283 L284	F228-F280 HydrophobicContact CE1-CE1 4.05Å; F228-F280 AromaticContact CE1-CZ 3.93Å; F228-F280 HydrophobicContact CE1-CZ 3.93Å; F228-F280 AromaticContact CZ-CE1 3.93Å; F228-F280 HydrophobicContact CZ-CE1 3.93Å; F228-F280 HydrophobicContact CZ-CZ 4.21Å; V238-F280 HydrophobicContact CB-CD1 3.96Å; V238-F280 HydrophobicContact CB-CE1 4.39Å; V238-F280 HydrophobicContact CB-CG 4.22Å; V238-F280 HydrophobicContact CG1-CB 4.2Å; V238-F280 HydrophobicContact CG1-CD1 3.73Å; V238-F280 HydrophobicContact CG1-CD2 3.85Å; V238-F280 HydrophobicContact CG1-CE1 4.01Å; V238-F280 HydrophobicContact CG1-CE2 4.13Å; V238-F280 HydrophobicContact CG1-CG 3.64Å; V238-F280 HydrophobicContact CG1-CZ 4.19Å; A239-F280 HydrophobicContact CB-CB 3.81Å; L242-F280 HydrophobicContact CD1-CB 4.11Å; L242-F280 HydrophobicContact CD1-CD2 3.59Å; L242-F280 HydrophobicContact CD1-CE2 4.41Å; L242-F280 HydrophobicContact CD1-CG 4.16Å; L271-F280 HydrophobicContact CB-CE2 4.46Å; V274-F280 HydrophobicContact CG2-CE1 4.11Å; V274-F280 HydrophobicContact CG2-CE2 4.48Å; V274-F280 HydrophobicContact CG2-CZ 3.45Å; V274-F280 VanDerWaalsContact CG2-CZ 3.45Å; S276-F280 WeakPolarHBondContact O-CE1 3.49Å; L277-F280 HydrophobicContact CD1-CD2 4.32Å; L277-F280 HydrophobicContact CD1-CE2 3.67Å; L277-F280 HydrophobicContact CD1-CZ 4.14Å; L277-F280 PolarHBondContact O-N 2.96Å; S278-F280 VanDerWaalsContact C-N 3.33Å; S278-F280 PolarHBondContact O-N 2.88Å; F280-A282 VanDerWaalsContact C-N 3.35Å; F280-A282 PolarHBondContact O-N 3.41Å; F280-Q283 VanDerWaalsContact C-OE1 3.22Å; F280-Q283 VanDerWaalsContact CA-OE1 3.27Å; F280-Q283 PolarHBondContact O-N 3.41Å; F280-Q283 PolarHBondContact O-OE1 3.41Å; F280-L284 HydrophobicContact CD2-CB 4.35Å; F280-L284 HydrophobicContact CD2-CD2 4.48Å; F280-L284 HydrophobicContact CE2-CD2 4.12Å; F280-L284 PolarHBondContact O-N 2.98Å
281	H	98	Very high	96.9	Very high	20 Å²	20	32 Å²	32	9%	0.093	16%	0.163	C	C	.	.	H	α-helix	trans	-57.6	-44	-175.4	178	-99.2	0	0	0	113.1	L277 Q283 L284 A285 M320 E324	L277-H281 HydrophobicContact CD1-CB 4.3Å; L277-H281 HydrophobicContact CG-CB 4.2Å; L277-H281 WeakPolarHBondContact O-CA 3.25Å; L277-H281 VanDerWaalsContact O-CB 3.3Å; L277-H281 WeakPolarHBondContact O-CB 3.44Å; L277-H281 PolarHBondContact O-N 3.5Å; H281-Q283 VanDerWaalsContact C-N 3.3Å; H281-Q283 PolarHBondContact O-N 3.35Å; H281-L284 PolarHBondContact O-N 2.93Å; H281-A285 WeakPolarHBondContact O-CB 3.49Å; H281-A285 PolarHBondContact O-N 3.5Å; H281-M320 HydrophobicContact CB-CE 3.19Å; H281-M320 PolarHBondContact CE1-O 3.23Å; H281-M320 PolarHBondContact NE2-O 2.72Å; H281-E324 IonicContact NE2-OE2 2.69Å
282	A	98	Very high	96.9	Very high	66 Å²	66	32.2 Å²	32.2	55%	0.545	16%	0.164	S	C	.	.	H	α-helix	trans	-60.6	-41.5	-179.5	0	0	0	0	0	111.7	F280 Y286	F280-A282 VanDerWaalsContact C-N 3.35Å; F280-A282 PolarHBondContact O-N 3.41Å; A282-Y286 WeakPolarHBondContact O-CB 3.3Å; A282-Y286 PolarHBondContact O-N 3.01Å
283	Q	98.5	Very high	96.8	Very high	56 Å²	56	37.4 Å²	37.4	26%	0.262	19%	0.189	S	C	.	.	H	α-helix	trans	-69.7	-35.9	177.8	-61.5	80.9	-5.6	0	0	111.5	L242 E243 F280 H281 C287	L242-Q283 HydrophobicContact CB-CB 3.7Å; L242-Q283 HydrophobicContact CD1-CB 4.46Å; E243-Q283 HydrophobicContact CB-CG 4.46Å; F280-Q283 VanDerWaalsContact C-OE1 3.22Å; F280-Q283 VanDerWaalsContact CA-OE1 3.27Å; F280-Q283 PolarHBondContact O-N 3.41Å; F280-Q283 PolarHBondContact O-OE1 3.41Å; H281-Q283 VanDerWaalsContact C-N 3.3Å; H281-Q283 PolarHBondContact O-N 3.35Å; Q283-C287 PolarHBondContact O-N 3.23Å; Q283-C287 VanDerWaalsContact O-N 3.12Å; Q283-C287 PolarHBondContact O-SG 3.14Å
284	L	98.7	Very high	96.8	Very high	0 Å²	0	37 Å²	37	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-66.9	-50.6	175.2	-176.6	55.5	0	0	0	111.4	L242 L268 L271 H272 L277 F280 H281 Y286 C287 I288	L242-L284 HydrophobicContact CD1-CB 3.91Å; L242-L284 HydrophobicContact CD1-CD1 4.38Å; L242-L284 HydrophobicContact CD2-CD1 4.11Å; L268-L284 HydrophobicContact CB-CD1 4.16Å; L268-L284 HydrophobicContact CD2-CD1 3.94Å; L271-L284 HydrophobicContact CB-CD1 4.28Å; L271-L284 HydrophobicContact CB-CD2 3.7Å; L271-L284 HydrophobicContact CD1-CD1 4.07Å; H272-L284 VanDerWaalsContact CE1-CD2 3.44Å; H272-L284 WeakPolarHBondContact CE1-CD2 3.18Å; H272-L284 VanDerWaalsContact NE2-CD2 3.29Å; H272-L284 WeakPolarHBondContact NE2-CD2 3.42Å; H272-L284 WeakPolarHBondContact NE2-CG 3.49Å; L277-L284 HydrophobicContact CD1-CD2 3.96Å; F280-L284 HydrophobicContact CD2-CB 4.35Å; F280-L284 HydrophobicContact CD2-CD2 4.48Å; F280-L284 HydrophobicContact CE2-CD2 4.12Å; F280-L284 PolarHBondContact O-N 2.98Å; H281-L284 PolarHBondContact O-N 2.93Å; L284-Y286 VanDerWaalsContact C-N 3.31Å; L284-Y286 PolarHBondContact O-N 3.27Å; L284-C287 WeakPolarHBondContact O-CA 3.45Å; L284-C287 WeakPolarHBondContact O-CB 3.45Å; L284-C287 PolarHBondContact O-N 3.02Å; L284-I288 WeakPolarHBondContact O-CG1 3.29Å; L284-I288 PolarHBondContact O-N 3.44Å
285	A	98.5	Very high	96.9	Very high	0 Å²	0	38.5 Å²	38.5	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-55.4	-46.3	176.5	0	0	0	0	0	111	H281 C287 I288 V289 E324	H281-A285 WeakPolarHBondContact O-CB 3.49Å; H281-A285 PolarHBondContact O-N 3.5Å; A285-C287 VanDerWaalsContact C-N 3.33Å; A285-C287 PolarHBondContact O-N 3.28Å; A285-I288 WeakPolarHBondContact O-CB 3.22Å; A285-I288 PolarHBondContact O-N 3.31Å; A285-V289 WeakPolarHBondContact O-CG2 3.43Å; A285-V289 PolarHBondContact O-N 3.37Å; A285-E324 HydrophobicContact CB-CB 4.18Å; A285-E324 HydrophobicContact CB-CG 3.81Å
286	Y	98.4	Very high	97.2	Very high	97 Å²	97	30.4 Å²	30.4	38%	0.38	16%	0.164	S	C	.	.	H	α-helix	trans	-56.2	-44.7	173.6	177.9	-105.6	0	0	0	112.3	A282 L284 I288 V289 Q290	A282-Y286 WeakPolarHBondContact O-CB 3.3Å; A282-Y286 PolarHBondContact O-N 3.01Å; L284-Y286 VanDerWaalsContact C-N 3.31Å; L284-Y286 PolarHBondContact O-N 3.27Å; Y286-I288 VanDerWaalsContact C-N 3.32Å; Y286-I288 PolarHBondContact O-N 3.05Å; Y286-V289 PolarHBondContact O-N 2.89Å; Y286-Q290 HydrophobicContact CD1-CG 4.21Å; Y286-Q290 HydrophobicContact CD2-CG 4.21Å; Y286-Q290 HydrophobicContact CE1-CG 3.81Å; Y286-Q290 HydrophobicContact CE2-CG 3.81Å; Y286-Q290 HydrophobicContact CG-CG 4.4Å; Y286-Q290 WeakPolarHBondContact O-CB 3.44Å; Y286-Q290 WeakPolarHBondContact O-CG 3.42Å; Y286-Q290 PolarHBondContact O-N 2.93Å
287	C	98.7	Very high	97.3	Very high	0 Å²	0	31.7 Å²	31.7	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-61.4	-39.8	175.9	-69.6	0	0	0	0	112.6	L242 G246 I249 L268 Q283 L284 A285 F291	L242-C287 PolarHBondContact O-SG 3.41Å; G246-C287 PolarHBondContact N-SG 3.06Å; I249-C287 HydrophobicContact CD1-CB 3.84Å; L268-C287 HydrophobicContact CD1-CB 4.05Å; Q283-C287 PolarHBondContact O-N 3.23Å; Q283-C287 VanDerWaalsContact O-N 3.12Å; Q283-C287 PolarHBondContact O-SG 3.14Å; L284-C287 WeakPolarHBondContact O-CA 3.45Å; L284-C287 WeakPolarHBondContact O-CB 3.45Å; L284-C287 PolarHBondContact O-N 3.02Å; A285-C287 VanDerWaalsContact C-N 3.33Å; A285-C287 PolarHBondContact O-N 3.28Å; C287-F291 WeakPolarHBondContact O-CD2 3.39Å; C287-F291 PolarHBondContact O-N 2.99Å; C287-F291 VanDerWaalsContact O-N 3.15Å
288	I	98.6	Very high	97.4	Very high	0 Å²	0	32.3 Å²	32.3	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-63.9	-52.4	177.7	-63.8	-60.8	0	0	0	110.2	L264 L268 L284 A285 Y286 Q290 F291 L292 V302 I328	L264-I288 HydrophobicContact CD1-CD1 3.44Å; L264-I288 VanDerWaalsContact CD1-CD1 3.44Å; L268-I288 HydrophobicContact CB-CD1 3.84Å; L268-I288 HydrophobicContact CD1-CD1 4.29Å; L284-I288 WeakPolarHBondContact O-CG1 3.29Å; L284-I288 PolarHBondContact O-N 3.44Å; A285-I288 WeakPolarHBondContact O-CB 3.22Å; A285-I288 PolarHBondContact O-N 3.31Å; Y286-I288 VanDerWaalsContact C-N 3.32Å; Y286-I288 PolarHBondContact O-N 3.05Å; I288-Q290 VanDerWaalsContact C-N 3.31Å; I288-Q290 PolarHBondContact O-N 3.36Å; I288-F291 WeakPolarHBondContact O-CB 3.14Å; I288-F291 PolarHBondContact O-N 3.38Å; I288-L292 HydrophobicContact CG2-CD1 4.49Å; I288-L292 WeakPolarHBondContact O-CG 3.28Å; I288-L292 PolarHBondContact O-N 3.06Å; I288-L292 VanDerWaalsContact O-N 3.14Å; I288-V302 HydrophobicContact CG2-CG1 3.54Å; I288-I328 HydrophobicContact CG2-CD1 3.85Å; I288-I328 HydrophobicContact CG2-CG1 4.2Å
289	V	98.2	Very high	97.6	Very high	14 Å²	14	30.5 Å²	30.5	9%	0.085	16%	0.163	C	C	.	.	H	α-helix	trans	-56.5	-45.4	178.1	172.3	0	0	0	0	110.9	A285 Y286 F291 L292 E293 E327 I328 V331	A285-V289 WeakPolarHBondContact O-CG2 3.43Å; A285-V289 PolarHBondContact O-N 3.37Å; Y286-V289 PolarHBondContact O-N 2.89Å; V289-F291 VanDerWaalsContact C-N 3.26Å; V289-F291 PolarHBondContact O-N 3.47Å; V289-L292 PolarHBondContact O-N 3.08Å; V289-E293 HydrophobicContact CG1-CG 4.41Å; V289-E293 PolarHBondContact O-N 2.97Å; V289-E327 HydrophobicContact CG2-CB 4.05Å; V289-I328 HydrophobicContact CG2-CG1 4.41Å; V289-V331 HydrophobicContact CG1-CG1 4.1Å; V289-V331 HydrophobicContact CG1-CG2 4.1Å
290	Q	98.1	Very high	97.7	Very high	12 Å²	12	29.9 Å²	29.9	6%	0.056	16%	0.158	C	C	.	.	H	α-helix	trans	-59.3	-34.3	176.4	-73.6	-61.5	-55.3	0	0	113.2	I249 N250 Y286 I288 E293 K294	I249-Q290 HydrophobicContact CB-CB 4.41Å; I249-Q290 HydrophobicContact CG2-CB 3.8Å; N250-Q290 VanDerWaalsContact CG-OE1 3.23Å; N250-Q290 PolarHBondContact ND2-OE1 2.89Å; Y286-Q290 HydrophobicContact CD1-CG 4.21Å; Y286-Q290 HydrophobicContact CD2-CG 4.21Å; Y286-Q290 HydrophobicContact CE1-CG 3.81Å; Y286-Q290 HydrophobicContact CE2-CG 3.81Å; Y286-Q290 HydrophobicContact CG-CG 4.4Å; Y286-Q290 WeakPolarHBondContact O-CB 3.44Å; Y286-Q290 WeakPolarHBondContact O-CG 3.42Å; Y286-Q290 PolarHBondContact O-N 2.93Å; I288-Q290 VanDerWaalsContact C-N 3.31Å; I288-Q290 PolarHBondContact O-N 3.36Å; Q290-E293 PolarHBondContact NE2-OE2 2.93Å; Q290-K294 VanDerWaalsContact O-CG 3.25Å; Q290-K294 WeakPolarHBondContact O-CG 3.48Å; Q290-K294 PolarHBondContact O-N 2.92Å
291	F	98.3	Very high	97.8	Very high	0 Å²	0	32.1 Å²	32.1	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-67.8	-39.2	173	-98	-72.6	0	0	0	112.5	I249 F252 L256 H260 F263 L264 L268 C287 I288 V289 K294 D295 L298	I249-F291 HydrophobicContact CD1-CD2 3.81Å; I249-F291 HydrophobicContact CD1-CE2 3.43Å; I249-F291 VanDerWaalsContact CD1-CE2 3.43Å; I249-F291 HydrophobicContact CD1-CZ 4.35Å; I249-F291 HydrophobicContact CG1-CD2 4.2Å; I249-F291 HydrophobicContact CG1-CE2 3.65Å; I249-F291 HydrophobicContact CG1-CZ 4.11Å; I249-F291 HydrophobicContact CG2-CD1 4.37Å; I249-F291 HydrophobicContact CG2-CD2 3.8Å; I249-F291 HydrophobicContact CG2-CE2 3.98Å; I249-F291 HydrophobicContact CG2-CG 4Å; I249-F291 HydrophobicContact CG2-CZ 4.35Å; F252-F291 HydrophobicContact CD2-CE1 4.41Å; F252-F291 HydrophobicContact CE2-CE1 4.13Å; F252-F291 AromaticContact CE2-CZ 3.86Å; F252-F291 HydrophobicContact CE2-CZ 3.86Å; L256-F291 HydrophobicContact CD1-CD1 4.01Å; L256-F291 HydrophobicContact CD1-CE1 4.31Å; H260-F291 HydrophobicContact CB-CE1 4Å; H260-F291 HydrophobicContact CB-CZ 4.27Å; H260-F291 WeakPolarHBondContact O-CZ 3.42Å; F263-F291 HydrophobicContact CD1-CE2 4.04Å; F263-F291 HydrophobicContact CD1-CZ 4.02Å; F263-F291 HydrophobicContact CE1-CE2 4.32Å; L264-F291 HydrophobicContact CB-CD1 4.37Å; L264-F291 HydrophobicContact CB-CD2 4.3Å; L264-F291 HydrophobicContact CB-CE1 4.3Å; L264-F291 HydrophobicContact CB-CE2 4.23Å; L264-F291 HydrophobicContact CB-CG 4.37Å; L264-F291 HydrophobicContact CB-CZ 4.23Å; L264-F291 HydrophobicContact CD1-CB 4.21Å; L264-F291 HydrophobicContact CD1-CD2 3.93Å; L264-F291 HydrophobicContact CD1-CG 4.11Å; L264-F291 HydrophobicContact CD2-CB 4.02Å; L264-F291 HydrophobicContact CD2-CD1 4.14Å; L264-F291 HydrophobicContact CD2-CG 4.03Å; L264-F291 HydrophobicContact CG-CG 4.4Å; L268-F291 HydrophobicContact CD1-CD2 3.78Å; L268-F291 HydrophobicContact CD1-CE2 3.57Å; C287-F291 WeakPolarHBondContact O-CD2 3.39Å; C287-F291 PolarHBondContact O-N 2.99Å; C287-F291 VanDerWaalsContact O-N 3.15Å; I288-F291 WeakPolarHBondContact O-CB 3.14Å; I288-F291 PolarHBondContact O-N 3.38Å; V289-F291 VanDerWaalsContact C-N 3.26Å; V289-F291 PolarHBondContact O-N 3.47Å; F291-K294 PolarHBondContact O-N 3.25Å; F291-D295 PolarHBondContact O-N 2.95Å; F291-D295 VanDerWaalsContact O-N 3.07Å; F291-L298 HydrophobicContact CD1-CD1 4.22Å
292	L	97.8	Very high	97.8	Very high	4 Å²	4	31.2 Å²	31.2	2%	0.021	17%	0.169	C	C	.	.	H	α-helix	trans	-70.8	-38.9	-179.2	-59.1	-171.5	0	0	0	111.8	I288 V289 K294 D295 L298 T299 V302 I328 V331	I288-L292 HydrophobicContact CG2-CD1 4.49Å; I288-L292 WeakPolarHBondContact O-CG 3.28Å; I288-L292 PolarHBondContact O-N 3.06Å; I288-L292 VanDerWaalsContact O-N 3.14Å; V289-L292 PolarHBondContact O-N 3.08Å; L292-K294 PolarHBondContact O-N 3.15Å; L292-D295 CarbonylContact O-C 3.57Å; L292-D295 PolarHBondContact O-N 3.39Å; L292-L298 HydrophobicContact CD2-CB 4.06Å; L292-T299 HydrophobicContact CD1-CG2 4.32Å; L292-V302 HydrophobicContact CD2-CB 4.34Å; L292-V302 HydrophobicContact CD2-CG2 4.01Å; L292-I328 HydrophobicContact CD1-CB 4.26Å; L292-I328 HydrophobicContact CD1-CG1 3.99Å; L292-I328 HydrophobicContact CD1-CG2 3.59Å; L292-V331 HydrophobicContact CB-CG2 4.41Å
293	E	96.6	Very high	97.7	Very high	109 Å²	109	28.1 Å²	28.1	51%	0.509	14%	0.144	S	C	.	.	H	α-helix	trans	-60.1	-31.3	171.8	-71	-175.7	160.1	0	0	112.3	V289 Q290 V331	V289-E293 HydrophobicContact CG1-CG 4.41Å; V289-E293 PolarHBondContact O-N 2.97Å; Q290-E293 PolarHBondContact NE2-OE2 2.93Å; E293-V331 HydrophobicContact CG-CG1 4.41Å
294	K	96.6	Very high	97.7	Very high	50 Å²	50	30.6 Å²	30.6	22%	0.217	15%	0.151	C	C	.	.	H	α-helix	trans	-79.1	-38.2	177.7	-69.7	-64.8	177.9	-168.9	0	113.5	N250 L254 L256 Q290 F291 L292	N250-K294 WeakPolarHBondContact O-CE 2.93Å; N250-K294 PolarHBondContact O-NZ 3.35Å; L254-K294 HydrophobicContact CD2-CB 4.02Å; L254-K294 HydrophobicContact CD2-CD 4.08Å; L254-K294 VanDerWaalsContact CD2-O 3.23Å; L254-K294 WeakPolarHBondContact CD2-O 3.48Å; L256-K294 HydrophobicContact CD1-CB 4.08Å; L256-K294 HydrophobicContact CD2-CB 4.22Å; L256-K294 HydrophobicContact CG-CB 4.32Å; Q290-K294 VanDerWaalsContact O-CG 3.25Å; Q290-K294 WeakPolarHBondContact O-CG 3.48Å; Q290-K294 PolarHBondContact O-N 2.92Å; F291-K294 PolarHBondContact O-N 3.25Å; L292-K294 PolarHBondContact O-N 3.15Å
295	D	97.2	Very high	97.6	Very high	31 Å²	31	31.1 Å²	31.1	17%	0.166	16%	0.156	C	C	.	.			trans	-149.6	93	-178	-174	-8.2	0	0	0	110.3	L256 K261 F291 L292 S297 L298	L256-D295 HydrophobicContact CD1-CB 3.63Å; L256-D295 HydrophobicContact CG-CB 4.34Å; K261-D295 WeakPolarHBondContact CE-OD2 3.46Å; K261-D295 IonicContact NZ-OD2 3Å; K261-D295 PolarHBondContact NZ-OD2 3.4Å; F291-D295 PolarHBondContact O-N 2.95Å; F291-D295 VanDerWaalsContact O-N 3.07Å; L292-D295 CarbonylContact O-C 3.57Å; L292-D295 PolarHBondContact O-N 3.39Å; D295-S297 VanDerWaalsContact CG-OG 3.27Å; D295-S297 PolarHBondContact O-N 3.06Å; D295-S297 VanDerWaalsContact OD1-CB 3.29Å; D295-S297 WeakPolarHBondContact OD1-CB 2.94Å; D295-S297 PolarHBondContact OD1-N 3.33Å; D295-S297 PolarHBondContact OD1-OG 3.04Å; D295-S297 PolarHBondContact OD2-OG 2.94Å; D295-L298 HydrophobicContact CB-CD1 3.93Å; D295-L298 HydrophobicContact CB-CG 4.1Å; D295-L298 WeakPolarHBondContact O-CB 3.39Å; D295-L298 PolarHBondContact O-N 3.1Å
296	P	96.9	Very high	97.6	Very high	34 Å²	34	31.3 Å²	31.3	22%	0.221	16%	0.157	C	C	.	.	G	3₁₀ helix	trans	-57.5	-21.9	-178.6	-29.3	37	0	0	0	114	L298 T299 E333 Q336	P296-L298 PolarHBondContact O-N 3.46Å; P296-L298 VanDerWaalsContact O-N 3.13Å; P296-T299 WeakPolarHBondContact O-CB 3.43Å; P296-T299 PolarHBondContact O-N 3.18Å; P296-T299 PolarHBondContact O-OG1 3.5Å; P296-E333 HydrophobicContact CB-CG 3.96Å; P296-E333 HydrophobicContact CG-CG 4.2Å; P296-E333 WeakPolarHBondContact CG-OE1 3.42Å; P296-Q336 HydrophobicContact CB-CG 4.4Å; P296-Q336 WeakPolarHBondContact O-CG 3.46Å
297	S	96.6	Very high	97.5	Very high	60 Å²	60	28.6 Å²	28.6	42%	0.42	15%	0.148	S	C	.	.	G	3₁₀ helix	trans	-63.5	-17.2	176.3	76.3	0	0	0	0	113.6	D295 T299	D295-S297 VanDerWaalsContact CG-OG 3.27Å; D295-S297 PolarHBondContact O-N 3.06Å; D295-S297 VanDerWaalsContact OD1-CB 3.29Å; D295-S297 WeakPolarHBondContact OD1-CB 2.94Å; D295-S297 PolarHBondContact OD1-N 3.33Å; D295-S297 PolarHBondContact OD1-OG 3.04Å; D295-S297 PolarHBondContact OD2-OG 2.94Å; S297-T299 VanDerWaalsContact C-N 3.29Å
298	L	97.6	Very high	97.4	Very high	13 Å²	13	36.5 Å²	36.5	7%	0.068	18%	0.183	C	C	.	.	G	3₁₀ helix	trans	-80.5	-8.1	176.6	-59.6	177.1	0	0	0	113.3	L256 K261 L264 F291 L292 D295 P296 E300 P301 V302	L256-L298 HydrophobicContact CD1-CD1 3.76Å; K261-L298 HydrophobicContact CD-CD2 4.07Å; K261-L298 HydrophobicContact CG-CD1 4.33Å; K261-L298 HydrophobicContact CG-CD2 4.15Å; L264-L298 HydrophobicContact CD2-CB 4.01Å; L264-L298 HydrophobicContact CD2-CD1 3.79Å; L264-L298 HydrophobicContact CD2-CG 4.36Å; F291-L298 HydrophobicContact CD1-CD1 4.22Å; L292-L298 HydrophobicContact CD2-CB 4.06Å; D295-L298 HydrophobicContact CB-CD1 3.93Å; D295-L298 HydrophobicContact CB-CG 4.1Å; D295-L298 WeakPolarHBondContact O-CB 3.39Å; D295-L298 PolarHBondContact O-N 3.1Å; P296-L298 PolarHBondContact O-N 3.46Å; P296-L298 VanDerWaalsContact O-N 3.13Å; L298-E300 PolarHBondContact O-N 3.41Å; L298-P301 WeakPolarHBondContact O-CD 3.4Å; L298-P301 VanDerWaalsContact O-CG 3.22Å; L298-P301 WeakPolarHBondContact O-CG 3.45Å; L298-V302 WeakPolarHBondContact O-CB 3.46Å; L298-V302 VanDerWaalsContact O-CG2 3.28Å; L298-V302 WeakPolarHBondContact O-CG2 3.44Å; L298-V302 PolarHBondContact O-N 3.24Å; L298-V302 VanDerWaalsContact O-N 3.16Å
299	T	97.6	Very high	97.3	Very high	1 Å²	1	39.3 Å²	39.3	1%	0.006	20%	0.195	C	C	.	.	H	α-helix	trans	-62.1	-45	-176.9	-52.5	0	0	0	0	112.4	L292 P296 S297 V302 I303 I328 I332 Q336	L292-T299 HydrophobicContact CD1-CG2 4.32Å; P296-T299 WeakPolarHBondContact O-CB 3.43Å; P296-T299 PolarHBondContact O-N 3.18Å; P296-T299 PolarHBondContact O-OG1 3.5Å; S297-T299 VanDerWaalsContact C-N 3.29Å; T299-V302 PolarHBondContact O-N 3.11Å; T299-I303 HydrophobicContact CG2-CD1 3.59Å; T299-I303 HydrophobicContact CG2-CG1 4.25Å; T299-I303 PolarHBondContact O-N 3.48Å; T299-I328 HydrophobicContact CG2-CG2 4.39Å; T299-I332 HydrophobicContact CG2-CD1 3.53Å; T299-I332 HydrophobicContact CG2-CG1 3.73Å; T299-Q336 HydrophobicContact CG2-CB 4.45Å
300	E	96.8	Very high	97.3	Very high	55 Å²	55	39.5 Å²	39.5	26%	0.257	19%	0.194	S	C	.	.	H	α-helix	trans	-59	-53.5	179.3	176.9	173.3	-171.1	0	0	113.2	L298 V302 I303 R304 I340	L298-E300 PolarHBondContact O-N 3.41Å; E300-V302 VanDerWaalsContact C-N 3.28Å; E300-V302 PolarHBondContact O-N 3.05Å; E300-I303 PolarHBondContact O-N 3.36Å; E300-R304 HydrophobicContact CG-CG 4.41Å; E300-R304 WeakPolarHBondContact O-CB 3.26Å; E300-R304 VanDerWaalsContact O-CG 3.29Å; E300-R304 WeakPolarHBondContact O-CG 3.41Å; E300-R304 PolarHBondContact O-N 3.26Å; E300-R304 IonicContact OE1-CZ 3.2Å; E300-R304 VanDerWaalsContact OE1-CZ 3.24Å; E300-R304 IonicContact OE1-NE 2.77Å; E300-R304 PolarHBondContact OE1-NE 3.4Å; E300-R304 IonicContact OE1-NH2 2.76Å; E300-R304 PolarHBondContact OE1-NH2 2.65Å; E300-I340 HydrophobicContact CB-CG2 4.07Å; E300-I340 HydrophobicContact CG-CG2 3.85Å
301	P	97.2	Very high	97.2	Very high	53 Å²	53	39.6 Å²	39.6	34%	0.344	20%	0.196	S	C	.	.	H	α-helix	trans	-64.1	-30.8	177.9	21.3	-30.8	0	0	0	113.3	L298 G305	L298-P301 WeakPolarHBondContact O-CD 3.4Å; L298-P301 VanDerWaalsContact O-CG 3.22Å; L298-P301 WeakPolarHBondContact O-CG 3.45Å; P301-G305 PolarHBondContact O-N 2.59Å
302	V	98.2	Very high	97	Very high	0 Å²	0	48.9 Å²	48.9	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-65.4	-56.4	174.7	167.8	0	0	0	0	111.1	L264 I269 I288 L292 L298 T299 E300 R304 G305 L306 I328	L264-V302 HydrophobicContact CD1-CG2 4.01Å; L264-V302 HydrophobicContact CD2-CG2 3.74Å; L264-V302 HydrophobicContact CG-CG2 4.06Å; I269-V302 HydrophobicContact CD1-CG2 4.16Å; I288-V302 HydrophobicContact CG2-CG1 3.54Å; L292-V302 HydrophobicContact CD2-CB 4.34Å; L292-V302 HydrophobicContact CD2-CG2 4.01Å; L298-V302 WeakPolarHBondContact O-CB 3.46Å; L298-V302 VanDerWaalsContact O-CG2 3.28Å; L298-V302 WeakPolarHBondContact O-CG2 3.44Å; L298-V302 PolarHBondContact O-N 3.24Å; L298-V302 VanDerWaalsContact O-N 3.16Å; T299-V302 PolarHBondContact O-N 3.11Å; E300-V302 VanDerWaalsContact C-N 3.28Å; E300-V302 PolarHBondContact O-N 3.05Å; V302-R304 VanDerWaalsContact C-N 3.32Å; V302-R304 PolarHBondContact O-N 3.31Å; V302-G305 CarbonylContact O-C 3.32Å; V302-G305 WeakPolarHBondContact O-CA 3.34Å; V302-G305 PolarHBondContact O-N 3.19Å; V302-L306 HydrophobicContact CG1-CD1 4.27Å; V302-L306 PolarHBondContact O-N 3.13Å; V302-I328 HydrophobicContact CG1-CD1 4.09Å
303	I	97.6	Very high	96.8	Very high	1 Å²	1	55.6 Å²	55.6	1%	0.005	28%	0.278	C	S	.	.	H	α-helix	trans	-61	-42.4	-178.5	-72.9	174.5	0	0	0	110.7	T299 E300 G305 L306 M307 L325 I328 I332 I340	T299-I303 HydrophobicContact CG2-CD1 3.59Å; T299-I303 HydrophobicContact CG2-CG1 4.25Å; T299-I303 PolarHBondContact O-N 3.48Å; E300-I303 PolarHBondContact O-N 3.36Å; I303-G305 VanDerWaalsContact C-N 3.29Å; I303-G305 PolarHBondContact O-N 3.4Å; I303-L306 PolarHBondContact O-N 3.36Å; I303-M307 HydrophobicContact CG2-CE 3.48Å; I303-M307 VanDerWaalsContact CG2-CE 3.48Å; I303-M307 HydrophobicContact CG2-SD 4.45Å; I303-M307 WeakPolarHBondContact O-CB 3.46Å; I303-M307 WeakPolarHBondContact O-CG 3.46Å; I303-M307 PolarHBondContact O-N 3.36Å; I303-L325 HydrophobicContact CG1-CD1 4.4Å; I303-I328 HydrophobicContact CD1-CG2 3.88Å; I303-I328 HydrophobicContact CG1-CG2 4.01Å; I303-I332 HydrophobicContact CD1-CD1 4.02Å; I303-I340 HydrophobicContact CD1-CD1 3.86Å; I303-I340 HydrophobicContact CD1-CG1 3.9Å; I303-I340 HydrophobicContact CG2-CB 4.2Å; I303-I340 HydrophobicContact CG2-CG1 4.46Å; I303-I340 HydrophobicContact CG2-CG2 4.42Å
304	R	96.9	Very high	96.7	Very high	109 Å²	109	52.6 Å²	52.6	41%	0.411	27%	0.268	S	S	.	.	H	α-helix	trans	-62.7	-36	173.6	-69.9	-176.1	-172.9	-65.8	-3.6	112.4	E300 V302 M307 K308 K339	E300-R304 HydrophobicContact CG-CG 4.41Å; E300-R304 WeakPolarHBondContact O-CB 3.26Å; E300-R304 VanDerWaalsContact O-CG 3.29Å; E300-R304 WeakPolarHBondContact O-CG 3.41Å; E300-R304 PolarHBondContact O-N 3.26Å; E300-R304 IonicContact OE1-CZ 3.2Å; E300-R304 VanDerWaalsContact OE1-CZ 3.24Å; E300-R304 IonicContact OE1-NE 2.77Å; E300-R304 PolarHBondContact OE1-NE 3.4Å; E300-R304 IonicContact OE1-NH2 2.76Å; E300-R304 PolarHBondContact OE1-NH2 2.65Å; V302-R304 VanDerWaalsContact C-N 3.32Å; V302-R304 PolarHBondContact O-N 3.31Å; R304-M307 HydrophobicContact CG-CE 4.2Å; R304-K308 WeakPolarHBondContact O-CB 3.35Å; R304-K308 PolarHBondContact O-N 2.92Å; R304-K339 PolarHBondContact NH2-O 3.12Å
305	G	97.5	Very high	96.6	Very high	11 Å²	11	52 Å²	52	11%	0.113	27%	0.27	C	S	.	.	H	α-helix	trans	-64	-48	174.5	0	0	0	0	0	112.9	P301 V302 I303 K308 F309	P301-G305 PolarHBondContact O-N 2.59Å; V302-G305 CarbonylContact O-C 3.32Å; V302-G305 WeakPolarHBondContact O-CA 3.34Å; V302-G305 PolarHBondContact O-N 3.19Å; I303-G305 VanDerWaalsContact C-N 3.29Å; I303-G305 PolarHBondContact O-N 3.4Å; G305-K308 WeakPolarHBondContact O-CB 3.49Å; G305-K308 PolarHBondContact O-N 3.23Å; G305-F309 WeakPolarHBondContact O-CD2 3.2Å; G305-F309 PolarHBondContact O-N 2.98Å
306	L	97.8	Very high	96.6	Very high	4 Å²	4	55.3 Å²	55.3	2%	0.021	29%	0.285	C	S	.	.	H	α-helix	trans	-60.9	-45.6	174.9	-67.5	176.6	0	0	0	111.2	V302 I303 K308 F309 W310 F321 I328	V302-L306 HydrophobicContact CG1-CD1 4.27Å; V302-L306 PolarHBondContact O-N 3.13Å; I303-L306 PolarHBondContact O-N 3.36Å; L306-K308 VanDerWaalsContact C-N 3.28Å; L306-K308 PolarHBondContact O-N 3.23Å; L306-F309 CarbonylContact O-C 3.56Å; L306-F309 PolarHBondContact O-N 3.42Å; L306-W310 PolarHBondContact O-N 3.27Å; L306-F321 HydrophobicContact CB-CE1 4.49Å; L306-F321 HydrophobicContact CD2-CE1 4.27Å; L306-I328 HydrophobicContact CD1-CD1 3.52Å
307	M	96.6	Very high	96.6	Very high	40 Å²	40	55 Å²	55	20%	0.197	28%	0.28	C	S	.	.	H	α-helix	trans	-60.9	-35.5	176.1	-74.4	-171.4	-75.4	0	0	113	I303 R304 F309 W310 P343	I303-M307 HydrophobicContact CG2-CE 3.48Å; I303-M307 VanDerWaalsContact CG2-CE 3.48Å; I303-M307 HydrophobicContact CG2-SD 4.45Å; I303-M307 WeakPolarHBondContact O-CB 3.46Å; I303-M307 WeakPolarHBondContact O-CG 3.46Å; I303-M307 PolarHBondContact O-N 3.36Å; R304-M307 HydrophobicContact CG-CE 4.2Å; M307-F309 VanDerWaalsContact C-N 3.29Å; M307-F309 PolarHBondContact O-N 3.03Å; M307-W310 WeakPolarHBondContact O-CB 3.38Å; M307-W310 PolarHBondContact O-N 3.35Å; M307-P343 HydrophobicContact CE-CB 3.83Å; M307-P343 HydrophobicContact CE-CG 3.95Å; M307-P343 VanDerWaalsContact SD-C 3.59Å; M307-P343 HydrophobicContact SD-CB 3.83Å
308	K	96.6	Very high	96.6	Very high	165 Å²	165	53.5 Å²	53.5	72%	0.717	27%	0.266	S	S	*	.	H	α-helix	trans	-63.8	-36.6	174.8	178.5	-174.4	174.2	-173.6	0	111.7	R304 G305 L306	R304-K308 WeakPolarHBondContact O-CB 3.35Å; R304-K308 PolarHBondContact O-N 2.92Å; G305-K308 WeakPolarHBondContact O-CB 3.49Å; G305-K308 PolarHBondContact O-N 3.23Å; L306-K308 VanDerWaalsContact C-N 3.28Å; L306-K308 PolarHBondContact O-N 3.23Å
309	F	96.5	Very high	96.6	Very high	59 Å²	59	54.6 Å²	54.6	26%	0.259	27%	0.274	S	S	.	.	T	Hydrogen-bonded Turn	trans	-98.8	13.6	-178.3	-62.7	-45.5	0	0	0	113.9	I269 P270 T273 G305 L306 M307	I269-F309 HydrophobicContact CG2-CD2 3.85Å; I269-F309 HydrophobicContact CG2-CE2 3.85Å; P270-F309 HydrophobicContact CG-CE2 4.36Å; T273-F309 HydrophobicContact CG2-CB 3.91Å; T273-F309 HydrophobicContact CG2-CD1 3.38Å; T273-F309 HydrophobicContact CG2-CD2 3.9Å; T273-F309 HydrophobicContact CG2-CE1 3.75Å; T273-F309 HydrophobicContact CG2-CE2 4.22Å; T273-F309 HydrophobicContact CG2-CG 3.47Å; T273-F309 VanDerWaalsContact CG2-CG 3.47Å; T273-F309 HydrophobicContact CG2-CZ 4.15Å; G305-F309 WeakPolarHBondContact O-CD2 3.2Å; G305-F309 PolarHBondContact O-N 2.98Å; L306-F309 CarbonylContact O-C 3.56Å; L306-F309 PolarHBondContact O-N 3.42Å; M307-F309 VanDerWaalsContact C-N 3.29Å; M307-F309 PolarHBondContact O-N 3.03Å
310	W	97.7	Very high	96.6	Very high	19 Å²	19	55.9 Å²	55.9	7%	0.072	28%	0.28	C	S	.	.			trans	-54.9	125.4	-177	-162.3	-86.5	0	0	0	111.6	L306 M307 K312 E318 F321 L322 L325 Q347 C351	L306-W310 PolarHBondContact O-N 3.27Å; M307-W310 WeakPolarHBondContact O-CB 3.38Å; M307-W310 PolarHBondContact O-N 3.35Å; W310-K312 PolarHBondContact O-N 2.95Å; W310-E318 HydrophobicContact CZ2-CG 4.1Å; W310-E318 PolarHBondContact NE1-OE1 3.15Å; W310-F321 HydrophobicContact CD2-CD1 4.29Å; W310-F321 HydrophobicContact CE3-CB 4.3Å; W310-F321 AromaticContact CE3-CD1 3.74Å; W310-F321 HydrophobicContact CE3-CD1 3.74Å; W310-F321 HydrophobicContact CE3-CG 4.46Å; W310-F321 HydrophobicContact CH2-CB 3.92Å; W310-F321 HydrophobicContact CZ2-CB 4.3Å; W310-F321 HydrophobicContact CZ3-CB 3.92Å; W310-F321 HydrophobicContact CZ3-CD1 4.03Å; W310-F321 HydrophobicContact CZ3-CG 4.49Å; W310-L322 HydrophobicContact CH2-CD2 3.89Å; W310-L322 HydrophobicContact CH2-CG 4.1Å; W310-L322 HydrophobicContact CZ2-CD2 4.02Å; W310-L322 HydrophobicContact CZ2-CG 4.05Å; W310-L325 HydrophobicContact CH2-CD2 4.19Å; W310-L325 HydrophobicContact CZ3-CD2 4.19Å; W310-Q347 HydrophobicContact CD2-CG 3.84Å; W310-Q347 HydrophobicContact CE3-CG 4.08Å; W310-Q347 HydrophobicContact CG-CG 4.32Å; W310-Q347 HydrophobicContact CH2-CG 4.4Å; W310-Q347 HydrophobicContact CZ2-CG 4.19Å; W310-Q347 HydrophobicContact CZ3-CG 4.35Å; W310-C351 VanDerWaalsContact CZ2-SG 3.5Å
311	P	96.6	Very high	96.7	Very high	14 Å²	14	53.4 Å²	53.4	9%	0.091	27%	0.268	C	S	.	.			trans	-62.4	133.4	-180	-21.5	32.7	0	0	0	111.3	K317 F321	P311-K317 HydrophobicContact CB-CB 3.85Å; P311-K317 HydrophobicContact CG-CB 3.56Å; P311-F321 HydrophobicContact CG-CD2 3.68Å; P311-F321 HydrophobicContact CG-CE1 4.45Å; P311-F321 HydrophobicContact CG-CE2 3.59Å; P311-F321 HydrophobicContact CG-CG 4.12Å; P311-F321 HydrophobicContact CG-CZ 3.98Å
312	K	94.4	Very high	96.8	Very high	194 Å²	194	50.9 Å²	50.9	84%	0.843	25%	0.252	S	S	*	.	S	Bend	trans	-115.2	-8.9	178	-62.4	-178.9	-175.1	174.2	0	113.8	W310	W310-K312 PolarHBondContact O-N 2.95Å
313	T	93.2	Very high	96.8	Very high	145 Å²	145	51.4 Å²	51.4	89%	0.89	26%	0.257	S	S	*	.	S	Bend	trans	-127.5	-10.6	-171.9	55.3	0	0	0	0	113.8
314	C	94.5	Very high	96.8	Very high	46 Å²	46	51.3 Å²	51.3	31%	0.311	26%	0.257	S	S	.	.			trans	-126.7	106.8	-179.1	179.1	0	0	0	0	109.1	Q316 K317 E318	C314-Q316 VanDerWaalsContact C-N 3.34Å; C314-K317 HydrophobicContact CB-CB 4.14Å; C314-K317 HydrophobicContact CB-CD 4.37Å; C314-K317 HydrophobicContact CB-CG 4.25Å; C314-K317 PolarHBondContact O-N 3.16Å; C314-E318 PolarHBondContact O-N 2.7Å; C314-E318 VanDerWaalsContact O-N 3.09Å
315	S	95.5	Very high	96.8	Very high	37 Å²	37	46.5 Å²	46.5	26%	0.259	24%	0.239	S	C	.	.	H	α-helix	trans	-65.7	-35.7	-179.1	51.2	0	0	0	0	112.4	E318 V319 H356	S315-E318 WeakPolarHBondContact O-CB 3.45Å; S315-E318 PolarHBondContact O-N 3.01Å; S315-E318 VanDerWaalsContact O-N 3.13Å; S315-V319 WeakPolarHBondContact O-CG2 3.29Å; S315-V319 PolarHBondContact O-N 2.92Å; S315-H356 VanDerWaalsContact CB-CD2 3.45Å; S315-H356 WeakPolarHBondContact CB-CD2 3.32Å; S315-H356 WeakPolarHBondContact CB-NE2 3.39Å; S315-H356 PolarHBondContact OG-CD2 3.42Å; S315-H356 PolarHBondContact OG-NE2 2.93Å
316	Q	95.4	Very high	96.9	Very high	102 Å²	102	47.5 Å²	47.5	48%	0.477	24%	0.241	S	C	.	.	H	α-helix	trans	-59.3	-48.3	175.2	-172.9	-178	5.2	0	0	111.3	C314 E318 V319 M320	C314-Q316 VanDerWaalsContact C-N 3.34Å; Q316-E318 VanDerWaalsContact C-N 3.29Å; Q316-E318 PolarHBondContact O-N 3.44Å; Q316-V319 PolarHBondContact O-N 2.99Å; Q316-M320 HydrophobicContact CG-SD 4.31Å; Q316-M320 VanDerWaalsContact O-CG 3.25Å; Q316-M320 WeakPolarHBondContact O-CG 3.18Å; Q316-M320 PolarHBondContact O-N 3.01Å
317	K	96.9	Very high	96.9	Very high	28 Å²	28	51.5 Å²	51.5	12%	0.122	26%	0.259	C	S	.	.	H	α-helix	trans	-62	-37	173.9	-72.7	-172.7	63.6	163.3	0	112	H272 T273 V274 P311 C314 M320 F321	H272-K317 WeakPolarHBondContact O-CE 3.32Å; H272-K317 PolarHBondContact O-NZ 3.3Å; T273-K317 PolarHBondContact O-NZ 3.13Å; T273-K317 VanDerWaalsContact O-NZ 3.15Å; V274-K317 PolarHBondContact O-NZ 3.25Å; P311-K317 HydrophobicContact CB-CB 3.85Å; P311-K317 HydrophobicContact CG-CB 3.56Å; C314-K317 HydrophobicContact CB-CB 4.14Å; C314-K317 HydrophobicContact CB-CD 4.37Å; C314-K317 HydrophobicContact CB-CG 4.25Å; C314-K317 PolarHBondContact O-N 3.16Å; K317-M320 WeakPolarHBondContact O-CB 3.47Å; K317-M320 PolarHBondContact O-N 3.12Å; K317-F321 WeakPolarHBondContact O-CD2 3.04Å; K317-F321 PolarHBondContact O-N 3.34Å
318	E	97.8	Very high	96.9	Very high	28 Å²	28	49.6 Å²	49.6	13%	0.131	25%	0.25	C	S	.	.	H	α-helix	trans	-63.5	-41	176.4	-173	166.2	-148.3	0	0	112.1	W310 C314 S315 Q316 M320 F321 L322 V359	W310-E318 HydrophobicContact CZ2-CG 4.1Å; W310-E318 PolarHBondContact NE1-OE1 3.15Å; C314-E318 PolarHBondContact O-N 2.7Å; C314-E318 VanDerWaalsContact O-N 3.09Å; S315-E318 WeakPolarHBondContact O-CB 3.45Å; S315-E318 PolarHBondContact O-N 3.01Å; S315-E318 VanDerWaalsContact O-N 3.13Å; Q316-E318 VanDerWaalsContact C-N 3.29Å; Q316-E318 PolarHBondContact O-N 3.44Å; E318-M320 VanDerWaalsContact C-N 3.32Å; E318-M320 PolarHBondContact O-N 2.92Å; E318-F321 PolarHBondContact O-N 3.25Å; E318-L322 WeakPolarHBondContact O-CG 3.4Å; E318-L322 PolarHBondContact O-N 3.02Å; E318-V359 HydrophobicContact CB-CG2 4.15Å; E318-V359 HydrophobicContact CG-CG1 3.8Å; E318-V359 HydrophobicContact CG-CG2 4.15Å
319	V	97.9	Very high	97	Very high	36 Å²	36	41.8 Å²	41.8	22%	0.218	22%	0.216	C	C	.	.	H	α-helix	trans	-61.9	-40	172.7	172.4	0	0	0	0	111.4	S315 Q316 L322 G323 Q358 V359 R362	S315-V319 WeakPolarHBondContact O-CG2 3.29Å; S315-V319 PolarHBondContact O-N 2.92Å; Q316-V319 PolarHBondContact O-N 2.99Å; V319-L322 PolarHBondContact O-N 3.14Å; V319-G323 PolarHBondContact O-N 2.94Å; V319-Q358 HydrophobicContact CG2-CB 4.08Å; V319-V359 HydrophobicContact CG2-CG2 3.91Å; V319-R362 HydrophobicContact CG1-CB 4.33Å; V319-R362 HydrophobicContact CG1-CG 4.07Å
320	M	97.8	Very high	97	Very high	28 Å²	28	42.5 Å²	42.5	14%	0.138	22%	0.223	C	C	.	.	H	α-helix	trans	-64.8	-45.4	177	-64.8	162.8	64.9	0	0	111.9	L277 S278 H281 Q316 K317 E318 L322 G323 E324	L277-M320 HydrophobicContact CB-CE 4.3Å; L277-M320 HydrophobicContact CD2-CE 4.12Å; L277-M320 HydrophobicContact CG-CE 3.75Å; S278-M320 VanDerWaalsContact CA-CE 3.43Å; H281-M320 HydrophobicContact CB-CE 3.19Å; H281-M320 PolarHBondContact CE1-O 3.23Å; H281-M320 PolarHBondContact NE2-O 2.72Å; Q316-M320 HydrophobicContact CG-SD 4.31Å; Q316-M320 VanDerWaalsContact O-CG 3.25Å; Q316-M320 WeakPolarHBondContact O-CG 3.18Å; Q316-M320 PolarHBondContact O-N 3.01Å; K317-M320 WeakPolarHBondContact O-CB 3.47Å; K317-M320 PolarHBondContact O-N 3.12Å; E318-M320 VanDerWaalsContact C-N 3.32Å; E318-M320 PolarHBondContact O-N 2.92Å; M320-L322 VanDerWaalsContact C-N 3.31Å; M320-L322 PolarHBondContact O-N 3.33Å; M320-G323 CarbonylContact O-C 3.55Å; M320-G323 VanDerWaalsContact O-CA 3.28Å; M320-G323 WeakPolarHBondContact O-CA 3.22Å; M320-G323 PolarHBondContact O-N 3.37Å; M320-E324 PolarHBondContact O-N 2.93Å
321	F	98.4	Very high	97	Very high	2 Å²	2	44 Å²	44	1%	0.009	23%	0.234	C	C	.	.	H	α-helix	trans	-60.1	-39.4	174.5	-89.3	-120.4	0	0	0	112.1	H272 L277 L306 W310 P311 K317 E318 G323 L325	H272-F321 HydrophobicContact CB-CE1 4.47Å; H272-F321 HydrophobicContact CB-CE2 4.08Å; H272-F321 HydrophobicContact CB-CZ 3.63Å; L277-F321 HydrophobicContact CD2-CD2 4.31Å; L277-F321 HydrophobicContact CD2-CE2 3.76Å; L306-F321 HydrophobicContact CB-CE1 4.49Å; L306-F321 HydrophobicContact CD2-CE1 4.27Å; W310-F321 HydrophobicContact CD2-CD1 4.29Å; W310-F321 HydrophobicContact CE3-CB 4.3Å; W310-F321 AromaticContact CE3-CD1 3.74Å; W310-F321 HydrophobicContact CE3-CD1 3.74Å; W310-F321 HydrophobicContact CE3-CG 4.46Å; W310-F321 HydrophobicContact CH2-CB 3.92Å; W310-F321 HydrophobicContact CZ2-CB 4.3Å; W310-F321 HydrophobicContact CZ3-CB 3.92Å; W310-F321 HydrophobicContact CZ3-CD1 4.03Å; W310-F321 HydrophobicContact CZ3-CG 4.49Å; P311-F321 HydrophobicContact CG-CD2 3.68Å; P311-F321 HydrophobicContact CG-CE1 4.45Å; P311-F321 HydrophobicContact CG-CE2 3.59Å; P311-F321 HydrophobicContact CG-CG 4.12Å; P311-F321 HydrophobicContact CG-CZ 3.98Å; K317-F321 WeakPolarHBondContact O-CD2 3.04Å; K317-F321 PolarHBondContact O-N 3.34Å; E318-F321 PolarHBondContact O-N 3.25Å; F321-G323 VanDerWaalsContact C-N 3.28Å; F321-L325 WeakPolarHBondContact O-CB 3.25Å; F321-L325 PolarHBondContact O-N 3.38Å
322	L	98.3	Very high	97	Very high	0 Å²	0	43.4 Å²	43.4	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-65	-33.9	172.1	-71.6	166.7	0	0	0	111.7	W310 E318 V319 M320 E326 C351 V359 R362 A363 Y366	W310-L322 HydrophobicContact CH2-CD2 3.89Å; W310-L322 HydrophobicContact CH2-CG 4.1Å; W310-L322 HydrophobicContact CZ2-CD2 4.02Å; W310-L322 HydrophobicContact CZ2-CG 4.05Å; E318-L322 WeakPolarHBondContact O-CG 3.4Å; E318-L322 PolarHBondContact O-N 3.02Å; V319-L322 PolarHBondContact O-N 3.14Å; M320-L322 VanDerWaalsContact C-N 3.31Å; M320-L322 PolarHBondContact O-N 3.33Å; L322-E326 PolarHBondContact O-N 3.17Å; L322-C351 HydrophobicContact CD1-CB 4.23Å; L322-C351 HydrophobicContact CD2-CB 4.21Å; L322-V359 HydrophobicContact CD1-CG1 4.04Å; L322-R362 HydrophobicContact CB-CG 3.68Å; L322-R362 HydrophobicContact CD1-CB 4.11Å; L322-R362 HydrophobicContact CD1-CG 4.11Å; L322-A363 HydrophobicContact CD1-CB 4.05Å; L322-A363 HydrophobicContact CD2-CB 4.11Å; L322-Y366 WeakPolarHBondContact CA-OH 3.23Å; L322-Y366 WeakPolarHBondContact O-CE1 3.39Å; L322-Y366 PolarHBondContact O-OH 3.03Å
323	G	97.9	Very high	97.2	Very high	11 Å²	11	38.4 Å²	38.4	11%	0.113	21%	0.209	C	C	.	.	H	α-helix	trans	-59.1	-59	171.1	0	0	0	0	0	112.9	V319 M320 F321 L325 E326 E327	V319-G323 PolarHBondContact O-N 2.94Å; M320-G323 CarbonylContact O-C 3.55Å; M320-G323 VanDerWaalsContact O-CA 3.28Å; M320-G323 WeakPolarHBondContact O-CA 3.22Å; M320-G323 PolarHBondContact O-N 3.37Å; F321-G323 VanDerWaalsContact C-N 3.28Å; G323-L325 VanDerWaalsContact C-N 3.29Å; G323-L325 PolarHBondContact O-N 3.32Å; G323-E326 WeakPolarHBondContact O-CB 3.28Å; G323-E326 PolarHBondContact O-N 3.07Å; G323-E326 VanDerWaalsContact O-N 3.13Å; G323-E327 PolarHBondContact O-N 3.43Å
324	E	98.2	Very high	97.4	Very high	0 Å²	0	34.1 Å²	34.1	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-60.2	-40.2	-179.5	-179.8	-176.9	174.9	0	0	112.1	H272 H281 A285 M320 E326 E327 I328	H272-E324 IonicContact CD2-OE1 3.83Å; H272-E324 IonicContact CD2-OE2 3.9Å; H272-E324 PolarHBondContact CD2-OE2 3.3Å; H272-E324 IonicContact CE1-OE1 3.91Å; H272-E324 IonicContact NE2-OE1 2.84Å; H272-E324 PolarHBondContact NE2-OE1 2.9Å; H272-E324 VanDerWaalsContact NE2-OE1 3.1Å; H272-E324 IonicContact NE2-OE2 3.24Å; H272-E324 PolarHBondContact NE2-OE2 3.37Å; H281-E324 IonicContact NE2-OE2 2.69Å; A285-E324 HydrophobicContact CB-CB 4.18Å; A285-E324 HydrophobicContact CB-CG 3.81Å; M320-E324 PolarHBondContact O-N 2.93Å; E324-E326 VanDerWaalsContact C-N 3.29Å; E324-E326 PolarHBondContact O-N 2.98Å; E324-E327 PolarHBondContact O-N 3.34Å; E324-I328 HydrophobicContact CG-CD1 3.97Å; E324-I328 WeakPolarHBondContact O-CG1 3.31Å; E324-I328 PolarHBondContact O-N 3.29Å
325	L	98.1	Very high	97.5	Very high	7 Å²	7	34.9 Å²	34.9	4%	0.037	19%	0.19	C	C	.	.	H	α-helix	trans	-65.4	-32.7	178.9	177.2	64.1	0	0	0	112.3	I303 W310 F321 G323 L329 L344 Y366	I303-L325 HydrophobicContact CG1-CD1 4.4Å; W310-L325 HydrophobicContact CH2-CD2 4.19Å; W310-L325 HydrophobicContact CZ3-CD2 4.19Å; F321-L325 WeakPolarHBondContact O-CB 3.25Å; F321-L325 PolarHBondContact O-N 3.38Å; G323-L325 VanDerWaalsContact C-N 3.29Å; G323-L325 PolarHBondContact O-N 3.32Å; L325-L329 HydrophobicContact CD1-CG 4.46Å; L325-L329 HydrophobicContact CG-CD1 4.33Å; L325-L329 WeakPolarHBondContact O-CB 3.39Å; L325-L329 WeakPolarHBondContact O-CG 3.45Å; L325-L329 PolarHBondContact O-N 3.15Å; L325-L344 HydrophobicContact CD1-CD1 3.63Å; L325-L344 HydrophobicContact CD2-CD1 3.35Å; L325-L344 HydrophobicContact CG-CD1 3.92Å; L325-Y366 VanDerWaalsContact CB-OH 3.32Å; L325-Y366 WeakPolarHBondContact CB-OH 3.43Å; L325-Y366 HydrophobicContact CD2-CE2 4.29Å; L325-Y366 HydrophobicContact CG-CE2 4.4Å; L325-Y366 WeakPolarHBondContact CG-OH 3.38Å
326	E	97.9	Very high	97.6	Very high	32 Å²	32	33.9 Å²	33.9	15%	0.15	18%	0.181	C	C	.	.	H	α-helix	trans	-65.2	-47.5	171.8	-173.7	172.2	179.7	0	0	111	L322 G323 E324 I328 L329 D330 R362 Y366 N369 I372	L322-E326 PolarHBondContact O-N 3.17Å; G323-E326 WeakPolarHBondContact O-CB 3.28Å; G323-E326 PolarHBondContact O-N 3.07Å; G323-E326 VanDerWaalsContact O-N 3.13Å; E324-E326 VanDerWaalsContact C-N 3.29Å; E324-E326 PolarHBondContact O-N 2.98Å; E326-I328 VanDerWaalsContact C-N 3.26Å; E326-I328 PolarHBondContact O-N 3.09Å; E326-L329 CarbonylContact O-C 3.58Å; E326-L329 WeakPolarHBondContact O-CA 3.24Å; E326-L329 PolarHBondContact O-N 2.98Å; E326-D330 PolarHBondContact O-N 3.47Å; E326-R362 IonicContact OE2-CZ 3.31Å; E326-R362 IonicContact OE2-NH1 3.36Å; E326-R362 PolarHBondContact OE2-NH1 3.13Å; E326-R362 IonicContact OE2-NH2 2.74Å; E326-R362 PolarHBondContact OE2-NH2 2.75Å; E326-Y366 HydrophobicContact CB-CD1 4.36Å; E326-Y366 HydrophobicContact CB-CE1 3.74Å; E326-Y366 HydrophobicContact CG-CD1 4.48Å; E326-Y366 HydrophobicContact CG-CE1 4.33Å; E326-Y366 PolarHBondContact N-OH 3.14Å; E326-N369 PolarHBondContact OE1-ND2 3.28Å; E326-I372 HydrophobicContact CG-CD1 3.88Å
327	E	97.7	Very high	97.7	Very high	89 Å²	89	29 Å²	29	42%	0.416	16%	0.159	S	C	.	.	H	α-helix	trans	-59.8	-36.9	177.4	-65.1	178.2	-153.4	0	0	112.2	V289 G323 E324 D330	V289-E327 HydrophobicContact CG2-CB 4.05Å; G323-E327 PolarHBondContact O-N 3.43Å; E324-E327 PolarHBondContact O-N 3.34Å; E327-D330 PolarHBondContact O-N 3.31Å
328	I	98.3	Very high	97.8	Very high	0 Å²	0	31.3 Å²	31.3	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-66.2	-41.4	173.8	-71.7	168.4	0	0	0	111.2	I288 V289 L292 T299 V302 I303 L306 E324 E326 D330 V331 I332	I288-I328 HydrophobicContact CG2-CD1 3.85Å; I288-I328 HydrophobicContact CG2-CG1 4.2Å; V289-I328 HydrophobicContact CG2-CG1 4.41Å; L292-I328 HydrophobicContact CD1-CB 4.26Å; L292-I328 HydrophobicContact CD1-CG1 3.99Å; L292-I328 HydrophobicContact CD1-CG2 3.59Å; T299-I328 HydrophobicContact CG2-CG2 4.39Å; V302-I328 HydrophobicContact CG1-CD1 4.09Å; I303-I328 HydrophobicContact CD1-CG2 3.88Å; I303-I328 HydrophobicContact CG1-CG2 4.01Å; L306-I328 HydrophobicContact CD1-CD1 3.52Å; E324-I328 HydrophobicContact CG-CD1 3.97Å; E324-I328 WeakPolarHBondContact O-CG1 3.31Å; E324-I328 PolarHBondContact O-N 3.29Å; E326-I328 VanDerWaalsContact C-N 3.26Å; E326-I328 PolarHBondContact O-N 3.09Å; I328-D330 VanDerWaalsContact C-N 3.29Å; I328-V331 WeakPolarHBondContact O-CG2 3.05Å; I328-V331 PolarHBondContact O-N 3.39Å; I328-I332 PolarHBondContact O-N 3.49Å; I328-I332 VanDerWaalsContact O-N 3.12Å
329	L	97.9	Very high	97.7	Very high	0 Å²	0	34.7 Å²	34.7	0%	0	19%	0.189	C	C	.	.	H	α-helix	trans	-69.4	-27.6	178.6	-71.5	172.1	0	0	0	112.2	L325 E326 V331 I332 F337 L344 Y366 Y371 I372	L325-L329 HydrophobicContact CD1-CG 4.46Å; L325-L329 HydrophobicContact CG-CD1 4.33Å; L325-L329 WeakPolarHBondContact O-CB 3.39Å; L325-L329 WeakPolarHBondContact O-CG 3.45Å; L325-L329 PolarHBondContact O-N 3.15Å; E326-L329 CarbonylContact O-C 3.58Å; E326-L329 WeakPolarHBondContact O-CA 3.24Å; E326-L329 PolarHBondContact O-N 2.98Å; L329-V331 PolarHBondContact O-N 3.11Å; L329-I332 HydrophobicContact CD2-CD1 4.22Å; L329-I332 HydrophobicContact CD2-CG2 4.16Å; L329-I332 WeakPolarHBondContact O-CG2 3.14Å; L329-I332 PolarHBondContact O-N 2.95Å; L329-F337 HydrophobicContact CD2-CD2 3.97Å; L329-F337 HydrophobicContact CD2-CE2 4.09Å; L329-L344 HydrophobicContact CD1-CD2 4.19Å; L329-L344 HydrophobicContact CD2-CD2 3.78Å; L329-Y366 HydrophobicContact CD1-CD2 4.29Å; L329-Y366 HydrophobicContact CD1-CE2 3.94Å; L329-Y371 VanDerWaalsContact O-CD1 3.29Å; L329-Y371 WeakPolarHBondContact O-CD1 3.38Å; L329-Y371 VanDerWaalsContact O-CE1 3.22Å; L329-Y371 WeakPolarHBondContact O-CE1 3.42Å; L329-I372 HydrophobicContact CB-CD1 3.85Å; L329-I372 HydrophobicContact CB-CG1 3.92Å; L329-I372 HydrophobicContact CD1-CD1 3.94Å; L329-I372 HydrophobicContact CD1-CG1 4.41Å
330	D	97	Very high	97.7	Very high	75 Å²	75	33 Å²	33	40%	0.401	18%	0.178	S	C	.	.	H	α-helix	trans	-64.8	-26.5	174.2	-81.7	-24.1	0	0	0	113.6	E326 E327 I328 N369	E326-D330 PolarHBondContact O-N 3.47Å; E327-D330 PolarHBondContact O-N 3.31Å; I328-D330 VanDerWaalsContact C-N 3.29Å; D330-N369 PolarHBondContact OD1-ND2 3.42Å; D330-N369 PolarHBondContact OD1-OD1 3.05Å
331	V	96.9	Very high	97.7	Very high	51 Å²	51	32.2 Å²	32.2	31%	0.309	17%	0.174	S	C	.	.	T	Hydrogen-bonded Turn	trans	-109.2	1	179.7	-58.4	0	0	0	0	113.6	V289 L292 E293 I328 L329	V289-V331 HydrophobicContact CG1-CG1 4.1Å; V289-V331 HydrophobicContact CG1-CG2 4.1Å; L292-V331 HydrophobicContact CB-CG2 4.41Å; E293-V331 HydrophobicContact CG-CG1 4.41Å; I328-V331 WeakPolarHBondContact O-CG2 3.05Å; I328-V331 PolarHBondContact O-N 3.39Å; L329-V331 PolarHBondContact O-N 3.11Å
332	I	98	Very high	97.6	Very high	1 Å²	1	36.7 Å²	36.7	1%	0.005	20%	0.196	C	C	.	.			trans	-70	136.8	-176.7	-162.8	165.9	0	0	0	110.9	T299 I303 I328 L329 Q336 F337 I340 Y371 L375	T299-I332 HydrophobicContact CG2-CD1 3.53Å; T299-I332 HydrophobicContact CG2-CG1 3.73Å; I303-I332 HydrophobicContact CD1-CD1 4.02Å; I328-I332 PolarHBondContact O-N 3.49Å; I328-I332 VanDerWaalsContact O-N 3.12Å; L329-I332 HydrophobicContact CD2-CD1 4.22Å; L329-I332 HydrophobicContact CD2-CG2 4.16Å; L329-I332 WeakPolarHBondContact O-CG2 3.14Å; L329-I332 PolarHBondContact O-N 2.95Å; I332-Q336 HydrophobicContact CD1-CB 4.41Å; I332-Q336 HydrophobicContact CG1-CB 4.05Å; I332-F337 HydrophobicContact CD1-CB 3.93Å; I332-F337 HydrophobicContact CD1-CD2 4.31Å; I332-F337 HydrophobicContact CG1-CB 4.31Å; I332-F337 HydrophobicContact CG2-CB 4.33Å; I332-F337 HydrophobicContact CG2-CD2 4.47Å; I332-I340 HydrophobicContact CD1-CD1 4.06Å; I332-I340 HydrophobicContact CD1-CG1 4.26Å; I332-Y371 HydrophobicContact CG2-CE1 4.25Å; I332-Y371 PolarHBondContact O-OH 3.04Å; I332-L375 HydrophobicContact CG2-CD1 3.61Å
333	E	97.3	Very high	97.6	Very high	88 Å²	88	38.6 Å²	38.6	41%	0.411	21%	0.208	S	C	.	.			trans	-75.5	141.8	166.8	-68.2	-175.7	173.4	0	0	110.8	P296 S335 Q336 F337	P296-E333 HydrophobicContact CB-CG 3.96Å; P296-E333 HydrophobicContact CG-CG 4.2Å; P296-E333 WeakPolarHBondContact CG-OE1 3.42Å; E333-S335 PolarHBondContact O-N 3.08Å; E333-S335 PolarHBondContact OE2-OG 2.95Å; E333-Q336 HydrophobicContact CB-CG 4.25Å; E333-Q336 PolarHBondContact O-N 2.84Å; E333-F337 PolarHBondContact O-N 3.27Å
334	P	97.4	Very high	97.5	Very high	56 Å²	56	38.1 Å²	38.1	36%	0.364	20%	0.203	S	C	.	.	H	α-helix	trans	-52.7	-35.5	176.4	-26.9	33.7	0	0	0	113	Q336 F337 V338 L375	P334-Q336 VanDerWaalsContact C-N 3.26Å; P334-Q336 PolarHBondContact O-N 2.99Å; P334-F337 PolarHBondContact O-N 3.19Å; P334-V338 WeakPolarHBondContact O-CG2 3.47Å; P334-V338 PolarHBondContact O-N 2.99Å; P334-L375 HydrophobicContact CB-CD2 4.06Å; P334-L375 HydrophobicContact CG-CD2 3.95Å
335	S	97.2	Very high	97.5	Very high	62 Å²	62	38.2 Å²	38.2	43%	0.434	20%	0.203	S	C	.	.	H	α-helix	trans	-61	-31.3	177.4	77.9	0	0	0	0	113.7	E333 K339	E333-S335 PolarHBondContact O-N 3.08Å; E333-S335 PolarHBondContact OE2-OG 2.95Å; S335-K339 WeakPolarHBondContact O-CE 3.4Å
336	Q	97.6	Very high	97.5	Very high	16 Å²	16	42.6 Å²	42.6	8%	0.075	22%	0.222	C	C	.	.	H	α-helix	trans	-87.4	-37.3	177.5	-55.6	-58.4	-36.2	0	0	110.9	P296 T299 I332 E333 P334 V338 K339	P296-Q336 HydrophobicContact CB-CG 4.4Å; P296-Q336 WeakPolarHBondContact O-CG 3.46Å; T299-Q336 HydrophobicContact CG2-CB 4.45Å; I332-Q336 HydrophobicContact CD1-CB 4.41Å; I332-Q336 HydrophobicContact CG1-CB 4.05Å; E333-Q336 HydrophobicContact CB-CG 4.25Å; E333-Q336 PolarHBondContact O-N 2.84Å; P334-Q336 VanDerWaalsContact C-N 3.26Å; P334-Q336 PolarHBondContact O-N 2.99Å; Q336-V338 VanDerWaalsContact C-N 3.32Å; Q336-V338 PolarHBondContact O-N 3.34Å; Q336-K339 WeakPolarHBondContact O-CB 3.38Å; Q336-K339 PolarHBondContact O-N 3.3Å
337	F	98	Very high	97.5	Very high	0 Å²	0	42.5 Å²	42.5	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-54.3	-46.4	177.9	178.9	-102.2	0	0	0	112.3	L329 I332 E333 P334 K339 I340 Q341 L344 F345 L375 N379 I383	L329-F337 HydrophobicContact CD2-CD2 3.97Å; L329-F337 HydrophobicContact CD2-CE2 4.09Å; I332-F337 HydrophobicContact CD1-CB 3.93Å; I332-F337 HydrophobicContact CD1-CD2 4.31Å; I332-F337 HydrophobicContact CG1-CB 4.31Å; I332-F337 HydrophobicContact CG2-CB 4.33Å; I332-F337 HydrophobicContact CG2-CD2 4.47Å; E333-F337 PolarHBondContact O-N 3.27Å; P334-F337 PolarHBondContact O-N 3.19Å; F337-K339 PolarHBondContact O-N 3.21Å; F337-I340 HydrophobicContact CD2-CD1 4.09Å; F337-I340 WeakPolarHBondContact O-CD1 3.28Å; F337-I340 PolarHBondContact O-N 2.87Å; F337-Q341 HydrophobicContact CD1-CB 4.35Å; F337-Q341 HydrophobicContact CE1-CB 4.03Å; F337-Q341 HydrophobicContact CZ-CB 4.21Å; F337-Q341 PolarHBondContact O-N 3.3Å; F337-L344 HydrophobicContact CE2-CD2 4.26Å; F337-F345 AromaticContact CE2-CE2 3.78Å; F337-F345 HydrophobicContact CE2-CE2 3.78Å; F337-F345 HydrophobicContact CE2-CZ 4.48Å; F337-F345 AromaticContact CZ-CE2 3.53Å; F337-F345 HydrophobicContact CZ-CE2 3.53Å; F337-F345 HydrophobicContact CZ-CZ 4.17Å; F337-L375 HydrophobicContact CD1-CB 4.14Å; F337-L375 HydrophobicContact CD1-CD2 4.4Å; F337-L375 HydrophobicContact CD2-CD1 4.05Å; F337-L375 HydrophobicContact CE1-CB 3.87Å; F337-L375 HydrophobicContact CE2-CB 4.28Å; F337-L375 HydrophobicContact CE2-CD1 4.32Å; F337-L375 HydrophobicContact CG-CB 4.45Å; F337-L375 HydrophobicContact CG-CD1 4.25Å; F337-L375 HydrophobicContact CG-CD2 4.41Å; F337-L375 HydrophobicContact CZ-CB 3.92Å; F337-N379 HydrophobicContact CE1-CB 4.22Å; F337-I383 HydrophobicContact CE1-CD1 3.86Å; F337-I383 HydrophobicContact CZ-CD1 3.74Å
338	V	97.7	Very high	97.5	Very high	75 Å²	75	38.3 Å²	38.3	46%	0.455	20%	0.202	S	C	.	.	H	α-helix	trans	-56.4	-29.5	179.1	174.7	0	0	0	0	112.9	P334 Q336 I340 Q341	P334-V338 WeakPolarHBondContact O-CG2 3.47Å; P334-V338 PolarHBondContact O-N 2.99Å; Q336-V338 VanDerWaalsContact C-N 3.32Å; Q336-V338 PolarHBondContact O-N 3.34Å; V338-I340 VanDerWaalsContact C-N 3.35Å; V338-Q341 PolarHBondContact O-NE2 3.22Å
339	K	96.9	Very high	97.4	Very high	99 Å²	99	38.6 Å²	38.6	43%	0.43	20%	0.204	S	C	.	.	H	α-helix	trans	-75.8	-23	-180	-56.1	177.2	-171.7	166.7	0	113.4	R304 S335 Q336 F337	R304-K339 PolarHBondContact NH2-O 3.12Å; S335-K339 WeakPolarHBondContact O-CE 3.4Å; Q336-K339 WeakPolarHBondContact O-CB 3.38Å; Q336-K339 PolarHBondContact O-N 3.3Å; F337-K339 PolarHBondContact O-N 3.21Å
340	I	96.8	Very high	97.4	Very high	0 Å²	0	44.8 Å²	44.8	0%	0	23%	0.231	C	C	.	.	H	α-helix	trans	-120.5	-9.3	-171.7	57.1	74.7	0	0	0	114.1	E300 I303 I332 F337 V338 E342 P343 L344	E300-I340 HydrophobicContact CB-CG2 4.07Å; E300-I340 HydrophobicContact CG-CG2 3.85Å; I303-I340 HydrophobicContact CD1-CD1 3.86Å; I303-I340 HydrophobicContact CD1-CG1 3.9Å; I303-I340 HydrophobicContact CG2-CB 4.2Å; I303-I340 HydrophobicContact CG2-CG1 4.46Å; I303-I340 HydrophobicContact CG2-CG2 4.42Å; I332-I340 HydrophobicContact CD1-CD1 4.06Å; I332-I340 HydrophobicContact CD1-CG1 4.26Å; F337-I340 HydrophobicContact CD2-CD1 4.09Å; F337-I340 WeakPolarHBondContact O-CD1 3.28Å; F337-I340 PolarHBondContact O-N 2.87Å; V338-I340 VanDerWaalsContact C-N 3.35Å; I340-E342 VanDerWaalsContact C-N 3.3Å; I340-E342 PolarHBondContact O-N 2.8Å; I340-P343 WeakPolarHBondContact O-CD 3.34Å; I340-P343 VanDerWaalsContact O-CG 3.24Å; I340-P343 WeakPolarHBondContact O-CG 3.5Å; I340-L344 HydrophobicContact CD1-CB 4.19Å; I340-L344 HydrophobicContact CD1-CD2 3.6Å; I340-L344 WeakPolarHBondContact O-CB 3.44Å; I340-L344 PolarHBondContact O-N 2.98Å
341	Q	97.6	Very high	97.4	Very high	12 Å²	12	41.2 Å²	41.2	6%	0.056	21%	0.212	C	C	.	.	H	α-helix	trans	-54.2	-42.8	-175.6	60.2	178.2	-30.9	0	0	113	F337 V338 L344 F345 V382	F337-Q341 HydrophobicContact CD1-CB 4.35Å; F337-Q341 HydrophobicContact CE1-CB 4.03Å; F337-Q341 HydrophobicContact CZ-CB 4.21Å; F337-Q341 PolarHBondContact O-N 3.3Å; V338-Q341 PolarHBondContact O-NE2 3.22Å; Q341-L344 PolarHBondContact O-N 3.31Å; Q341-F345 HydrophobicContact CB-CD2 4.43Å; Q341-F345 WeakPolarHBondContact O-CB 3.44Å; Q341-F345 VanDerWaalsContact O-CD2 3.28Å; Q341-F345 WeakPolarHBondContact O-CD2 3.32Å; Q341-F345 PolarHBondContact O-N 2.93Å; Q341-V382 HydrophobicContact CG-CG1 4.32Å
342	E	97.7	Very high	97.3	Very high	97 Å²	97	38.8 Å²	38.8	45%	0.453	20%	0.197	S	C	.	.	H	α-helix	trans	-62.5	-58.2	-179	-83.4	-163	-127	0	0	113.5	I340 L344 K346 V382 I386	I340-E342 VanDerWaalsContact C-N 3.3Å; I340-E342 PolarHBondContact O-N 2.8Å; E342-L344 VanDerWaalsContact C-N 3.29Å; E342-L344 PolarHBondContact O-N 3.18Å; E342-K346 WeakPolarHBondContact O-CB 3.44Å; E342-K346 WeakPolarHBondContact O-CD 3.4Å; E342-K346 WeakPolarHBondContact O-CG 3.42Å; E342-K346 PolarHBondContact O-N 3.48Å; E342-K346 IonicContact OE2-NZ 3.64Å; E342-K346 PolarHBondContact OE2-NZ 3.21Å; E342-V382 HydrophobicContact CG-CG1 3.71Å; E342-I386 HydrophobicContact CB-CD1 4.47Å; E342-I386 HydrophobicContact CG-CD1 4.17Å
343	P	96.9	Very high	97.2	Very high	40 Å²	40	39.7 Å²	39.7	26%	0.26	20%	0.204	S	C	.	.	H	α-helix	trans	-64.5	-35.4	178.8	25.1	-34.7	0	0	0	112.2	M307 I340 Q347	M307-P343 HydrophobicContact CE-CB 3.83Å; M307-P343 HydrophobicContact CE-CG 3.95Å; M307-P343 VanDerWaalsContact SD-C 3.59Å; M307-P343 HydrophobicContact SD-CB 3.83Å; I340-P343 WeakPolarHBondContact O-CD 3.34Å; I340-P343 VanDerWaalsContact O-CG 3.24Å; I340-P343 WeakPolarHBondContact O-CG 3.5Å; P343-Q347 PolarHBondContact O-N 3.32Å; P343-Q347 VanDerWaalsContact O-N 3.17Å
344	L	97.5	Very high	97.1	Very high	1 Å²	1	36.3 Å²	36.3	1%	0.005	19%	0.19	C	C	.	.	H	α-helix	trans	-60	-56.5	176.7	174.3	62.2	0	0	0	111.6	L325 L329 F337 I340 Q341 E342 K346 Q347 I348	L325-L344 HydrophobicContact CD1-CD1 3.63Å; L325-L344 HydrophobicContact CD2-CD1 3.35Å; L325-L344 HydrophobicContact CG-CD1 3.92Å; L329-L344 HydrophobicContact CD1-CD2 4.19Å; L329-L344 HydrophobicContact CD2-CD2 3.78Å; F337-L344 HydrophobicContact CE2-CD2 4.26Å; I340-L344 HydrophobicContact CD1-CB 4.19Å; I340-L344 HydrophobicContact CD1-CD2 3.6Å; I340-L344 WeakPolarHBondContact O-CB 3.44Å; I340-L344 PolarHBondContact O-N 2.98Å; Q341-L344 PolarHBondContact O-N 3.31Å; E342-L344 VanDerWaalsContact C-N 3.29Å; E342-L344 PolarHBondContact O-N 3.18Å; L344-K346 VanDerWaalsContact C-N 3.3Å; L344-K346 PolarHBondContact O-N 3.11Å; L344-Q347 WeakPolarHBondContact O-CA 3.43Å; L344-Q347 WeakPolarHBondContact O-CB 3.45Å; L344-Q347 PolarHBondContact O-N 3.48Å; L344-I348 HydrophobicContact CD1-CD1 3.98Å; L344-I348 HydrophobicContact CD1-CG1 4.34Å; L344-I348 HydrophobicContact CG-CD1 3.88Å; L344-I348 PolarHBondContact O-N 3.46Å
345	F	97.9	Very high	96.9	Very high	1 Å²	1	38.4 Å²	38.4	0%	0.004	20%	0.204	C	C	.	.	H	α-helix	trans	-71	-25.9	-177.6	-80.6	-88.9	0	0	0	112.6	F337 Q341 Q347 I348 A349 I376 I383 I386 M387	F337-F345 AromaticContact CE2-CE2 3.78Å; F337-F345 HydrophobicContact CE2-CE2 3.78Å; F337-F345 HydrophobicContact CE2-CZ 4.48Å; F337-F345 AromaticContact CZ-CE2 3.53Å; F337-F345 HydrophobicContact CZ-CE2 3.53Å; F337-F345 HydrophobicContact CZ-CZ 4.17Å; Q341-F345 HydrophobicContact CB-CD2 4.43Å; Q341-F345 WeakPolarHBondContact O-CB 3.44Å; Q341-F345 VanDerWaalsContact O-CD2 3.28Å; Q341-F345 WeakPolarHBondContact O-CD2 3.32Å; Q341-F345 PolarHBondContact O-N 2.93Å; F345-Q347 PolarHBondContact O-N 2.86Å; F345-I348 HydrophobicContact CD1-CD1 4.07Å; F345-I348 HydrophobicContact CE1-CD1 4.08Å; F345-I348 HydrophobicContact CG-CD1 4.36Å; F345-I348 HydrophobicContact CZ-CD1 4.33Å; F345-I348 PolarHBondContact O-N 3.27Å; F345-A349 WeakPolarHBondContact O-CB 3.32Å; F345-A349 PolarHBondContact O-N 2.95Å; F345-I376 HydrophobicContact CE1-CD1 3.91Å; F345-I376 HydrophobicContact CE1-CG1 4.03Å; F345-I376 HydrophobicContact CZ-CD1 3.84Å; F345-I376 HydrophobicContact CZ-CG1 3.59Å; F345-I383 HydrophobicContact CD1-CG2 3.49Å; F345-I383 VanDerWaalsContact CD1-CG2 3.49Å; F345-I383 HydrophobicContact CD2-CD1 4.07Å; F345-I383 HydrophobicContact CD2-CG1 3.89Å; F345-I383 HydrophobicContact CD2-CG2 4.29Å; F345-I383 HydrophobicContact CE1-CG2 3.62Å; F345-I383 HydrophobicContact CE2-CD1 3.71Å; F345-I383 HydrophobicContact CE2-CG1 4.06Å; F345-I383 HydrophobicContact CE2-CG2 4.42Å; F345-I383 HydrophobicContact CG-CG1 4.19Å; F345-I383 HydrophobicContact CG-CG2 3.85Å; F345-I383 HydrophobicContact CZ-CD1 4Å; F345-I383 HydrophobicContact CZ-CG1 4.47Å; F345-I383 HydrophobicContact CZ-CG2 4.1Å; F345-I386 HydrophobicContact CB-CG2 4.07Å; F345-M387 HydrophobicContact CB-SD 4.31Å; F345-M387 HydrophobicContact CD1-CG 3.86Å; F345-M387 HydrophobicContact CD1-SD 3.85Å
346	K	97.5	Very high	96.8	Very high	100 Å²	100	38.5 Å²	38.5	44%	0.435	20%	0.197	S	C	.	.	H	α-helix	trans	-62.2	-32.4	167.4	-76.7	167.8	-173.1	157	0	111.8	E342 L344 K350 I386	E342-K346 WeakPolarHBondContact O-CB 3.44Å; E342-K346 WeakPolarHBondContact O-CD 3.4Å; E342-K346 WeakPolarHBondContact O-CG 3.42Å; E342-K346 PolarHBondContact O-N 3.48Å; E342-K346 IonicContact OE2-NZ 3.64Å; E342-K346 PolarHBondContact OE2-NZ 3.21Å; L344-K346 VanDerWaalsContact C-N 3.3Å; L344-K346 PolarHBondContact O-N 3.11Å; K346-K350 WeakPolarHBondContact O-CG 3.44Å; K346-I386 HydrophobicContact CB-CG2 4.46Å; K346-I386 HydrophobicContact CG-CG2 3.82Å
347	Q	97.6	Very high	96.7	Very high	29 Å²	29	41.3 Å²	41.3	14%	0.136	21%	0.209	C	C	.	.	H	α-helix	trans	-78.9	-44.5	174.9	-172	54.3	38.1	0	0	111.7	W310 P343 L344 F345 A349 K350 C351	W310-Q347 HydrophobicContact CD2-CG 3.84Å; W310-Q347 HydrophobicContact CE3-CG 4.08Å; W310-Q347 HydrophobicContact CG-CG 4.32Å; W310-Q347 HydrophobicContact CH2-CG 4.4Å; W310-Q347 HydrophobicContact CZ2-CG 4.19Å; W310-Q347 HydrophobicContact CZ3-CG 4.35Å; P343-Q347 PolarHBondContact O-N 3.32Å; P343-Q347 VanDerWaalsContact O-N 3.17Å; L344-Q347 WeakPolarHBondContact O-CA 3.43Å; L344-Q347 WeakPolarHBondContact O-CB 3.45Å; L344-Q347 PolarHBondContact O-N 3.48Å; F345-Q347 PolarHBondContact O-N 2.86Å; Q347-A349 VanDerWaalsContact C-N 3.29Å; Q347-A349 PolarHBondContact O-N 3.06Å; Q347-K350 WeakPolarHBondContact O-CB 3.28Å; Q347-K350 PolarHBondContact O-N 2.81Å; Q347-C351 PolarHBondContact O-N 2.92Å; Q347-C351 VanDerWaalsContact O-N 3.1Å; Q347-C351 PolarHBondContact O-SG 3.24Å
348	I	97.4	Very high	96.6	Very high	1 Å²	1	45.9 Å²	45.9	1%	0.005	23%	0.23	C	C	.	.	H	α-helix	trans	-58	-42.2	175.4	-63.9	169.2	0	0	0	110.8	L344 F345 K350 C351 V352 Y366 W367 M387	L344-I348 HydrophobicContact CD1-CD1 3.98Å; L344-I348 HydrophobicContact CD1-CG1 4.34Å; L344-I348 HydrophobicContact CG-CD1 3.88Å; L344-I348 PolarHBondContact O-N 3.46Å; F345-I348 HydrophobicContact CD1-CD1 4.07Å; F345-I348 HydrophobicContact CE1-CD1 4.08Å; F345-I348 HydrophobicContact CG-CD1 4.36Å; F345-I348 HydrophobicContact CZ-CD1 4.33Å; F345-I348 PolarHBondContact O-N 3.27Å; I348-K350 PolarHBondContact O-N 3.39Å; I348-C351 WeakPolarHBondContact O-CB 3.28Å; I348-C351 PolarHBondContact O-N 3.38Å; I348-V352 HydrophobicContact CG2-CG2 4.16Å; I348-V352 WeakPolarHBondContact O-CG2 3.4Å; I348-V352 PolarHBondContact O-N 3.48Å; I348-Y366 HydrophobicContact CD1-CD2 3.86Å; I348-Y366 HydrophobicContact CD1-CE2 3.76Å; I348-Y366 HydrophobicContact CG1-CE2 4.24Å; I348-W367 HydrophobicContact CG2-CH2 3.99Å; I348-W367 HydrophobicContact CG2-CZ3 4.24Å; I348-M387 HydrophobicContact CB-SD 4.45Å; I348-M387 HydrophobicContact CG2-CE 4.19Å; I348-M387 HydrophobicContact CG2-SD 4.28Å
349	A	97.4	Very high	96.6	Very high	6 Å²	6	42.3 Å²	42.3	5%	0.05	21%	0.209	C	C	.	.	H	α-helix	trans	-56.1	-36.8	176.1	0	0	0	0	0	113.1	F345 Q347 S353 M387 S390	F345-A349 WeakPolarHBondContact O-CB 3.32Å; F345-A349 PolarHBondContact O-N 2.95Å; Q347-A349 VanDerWaalsContact C-N 3.29Å; Q347-A349 PolarHBondContact O-N 3.06Å; A349-S353 WeakPolarHBondContact O-CB 3.47Å; A349-S353 PolarHBondContact O-N 2.97Å; A349-S353 VanDerWaalsContact O-N 3.15Å; A349-S353 PolarHBondContact O-OG 2.94Å; A349-M387 HydrophobicContact CB-CE 4.14Å; A349-M387 HydrophobicContact CB-SD 3.68Å; A349-S390 PolarHBondContact O-OG 3.27Å
350	K	96.5	Very high	96.6	Very high	131 Å²	131	37.6 Å²	37.6	57%	0.57	19%	0.188	S	C	*	.	H	α-helix	trans	-71	-41.3	174.5	-64.8	171.9	-169.8	167.3	0	111.6	K346 Q347 I348 S353 S354	K346-K350 WeakPolarHBondContact O-CG 3.44Å; Q347-K350 WeakPolarHBondContact O-CB 3.28Å; Q347-K350 PolarHBondContact O-N 2.81Å; I348-K350 PolarHBondContact O-N 3.39Å; K350-S353 CarbonylContact O-C 3.37Å; K350-S353 WeakPolarHBondContact O-CA 3.5Å; K350-S353 WeakPolarHBondContact O-CB 3.38Å; K350-S353 PolarHBondContact O-N 3.3Å; K350-S353 VanDerWaalsContact O-N 3.11Å; K350-S354 PolarHBondContact O-N 3.28Å
351	C	97.1	Very high	96.6	Very high	0 Å²	0	40.4 Å²	40.4	0%	0	20%	0.201	C	C	.	.	H	α-helix	trans	-64.4	-44.7	179.4	-57.5	0	0	0	0	111.3	W310 L322 Q347 I348 S353 S354 V359 A360 A363	W310-C351 VanDerWaalsContact CZ2-SG 3.5Å; L322-C351 HydrophobicContact CD1-CB 4.23Å; L322-C351 HydrophobicContact CD2-CB 4.21Å; Q347-C351 PolarHBondContact O-N 2.92Å; Q347-C351 VanDerWaalsContact O-N 3.1Å; Q347-C351 PolarHBondContact O-SG 3.24Å; I348-C351 WeakPolarHBondContact O-CB 3.28Å; I348-C351 PolarHBondContact O-N 3.38Å; C351-S353 PolarHBondContact O-N 3.02Å; C351-S354 WeakPolarHBondContact O-CB 3.28Å; C351-S354 PolarHBondContact O-N 3.35Å; C351-V359 HydrophobicContact CB-CG1 4.03Å; C351-A360 WeakPolarHBondContact O-CA 3.37Å; C351-A363 HydrophobicContact CB-CB 3.81Å
352	V	96.2	Very high	96.6	Very high	0 Å²	0	42.6 Å²	42.6	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-60.5	-32.7	172.3	172	0	0	0	0	111.6	I348 S354 A363 L364 W367 M387 L391	I348-V352 HydrophobicContact CG2-CG2 4.16Å; I348-V352 WeakPolarHBondContact O-CG2 3.4Å; I348-V352 PolarHBondContact O-N 3.48Å; V352-S354 VanDerWaalsContact C-N 3.27Å; V352-S354 PolarHBondContact O-N 2.99Å; V352-A363 HydrophobicContact CG2-CB 3.79Å; V352-L364 HydrophobicContact CG1-CD2 3.8Å; V352-L364 HydrophobicContact CG1-CG 4.2Å; V352-L364 HydrophobicContact CG2-CD2 4.11Å; V352-L364 HydrophobicContact CG2-CG 4.22Å; V352-W367 HydrophobicContact CG2-CH2 4.43Å; V352-W367 HydrophobicContact CG2-CZ3 4.22Å; V352-M387 HydrophobicContact CG2-CE 4.13Å; V352-L391 HydrophobicContact CG1-CD2 3.79Å
353	S	94.9	Very high	96.7	Very high	20 Å²	20	38 Å²	38	14%	0.14	19%	0.187	C	C	.	.	T	Hydrogen-bonded Turn	trans	-83.4	3.4	174.5	-61.4	0	0	0	0	114.7	A349 K350 C351 S390 R393	A349-S353 WeakPolarHBondContact O-CB 3.47Å; A349-S353 PolarHBondContact O-N 2.97Å; A349-S353 VanDerWaalsContact O-N 3.15Å; A349-S353 PolarHBondContact O-OG 2.94Å; K350-S353 CarbonylContact O-C 3.37Å; K350-S353 WeakPolarHBondContact O-CA 3.5Å; K350-S353 WeakPolarHBondContact O-CB 3.38Å; K350-S353 PolarHBondContact O-N 3.3Å; K350-S353 VanDerWaalsContact O-N 3.11Å; C351-S353 PolarHBondContact O-N 3.02Å; S353-S390 VanDerWaalsContact OG-CB 3.28Å; S353-S390 WeakPolarHBondContact OG-CB 3.2Å; S353-S390 PolarHBondContact OG-OG 3.28Å; S353-R393 PolarHBondContact OG-NH2 3.4Å
354	S	94.7	Very high	96.7	Very high	17 Å²	17	36.2 Å²	36.2	12%	0.119	18%	0.176	C	C	.	.			trans	-66.1	136.7	-178.5	-174.8	0	0	0	0	110	K350 C351 V352 H356	K350-S354 PolarHBondContact O-N 3.28Å; C351-S354 WeakPolarHBondContact O-CB 3.28Å; C351-S354 PolarHBondContact O-N 3.35Å; V352-S354 VanDerWaalsContact C-N 3.27Å; V352-S354 PolarHBondContact O-N 2.99Å; S354-H356 PolarHBondContact O-N 3.44Å; S354-H356 PolarHBondContact OG-N 3.32Å
355	P	93.5	Very high	96.6	Very high	100 Å²	100	40.2 Å²	40.2	65%	0.649	19%	0.191	S	C	*	.	S	Bend	trans	-69.2	-15.7	172.1	30.1	-35.4	0	0	0	112.4	F357 W399	P355-F357 PolarHBondContact O-N 3.22Å; P355-W399 PolarHBondContact O-NE1 3.24Å; P355-W399 VanDerWaalsContact O-NE1 3.14Å
356	H	95.3	Very high	96.6	Very high	63 Å²	63	40.2 Å²	40.2	29%	0.292	19%	0.192	S	C	.	.	S	Bend	trans	-82.6	111.7	179	-166.2	-71.8	0	0	0	110.1	S315 S354 Q358 V359 A360	S315-H356 VanDerWaalsContact CB-CD2 3.45Å; S315-H356 WeakPolarHBondContact CB-CD2 3.32Å; S315-H356 WeakPolarHBondContact CB-NE2 3.39Å; S315-H356 PolarHBondContact OG-CD2 3.42Å; S315-H356 PolarHBondContact OG-NE2 2.93Å; S354-H356 PolarHBondContact O-N 3.44Å; S354-H356 PolarHBondContact OG-N 3.32Å; H356-Q358 VanDerWaalsContact C-N 3.33Å; H356-Q358 PolarHBondContact CE1-OE1 2.92Å; H356-Q358 PolarHBondContact ND1-N 2.99Å; H356-Q358 PolarHBondContact O-N 3.47Å; H356-V359 HydrophobicContact CB-CB 4.41Å; H356-V359 HydrophobicContact CB-CG2 4.21Å; H356-V359 PolarHBondContact O-N 3.44Å; H356-A360 PolarHBondContact O-N 3.47Å; H356-A360 VanDerWaalsContact O-N 3.17Å
357	F	95.1	Very high	96.6	Very high	75 Å²	75	36.5 Å²	36.5	33%	0.329	18%	0.175	S	C	.	.	H	α-helix	trans	-58.8	-40.4	-168.9	79.7	-86.6	0	0	0	113.2	P355 V359 A360 E361 W399 I403	P355-F357 PolarHBondContact O-N 3.22Å; F357-V359 VanDerWaalsContact C-N 3.27Å; F357-V359 PolarHBondContact O-N 3.17Å; F357-A360 PolarHBondContact O-N 3.21Å; F357-E361 WeakPolarHBondContact O-CB 3.21Å; F357-E361 PolarHBondContact O-N 2.96Å; F357-W399 HydrophobicContact CB-CZ2 4.19Å; F357-W399 HydrophobicContact CD1-CZ2 4.44Å; F357-I403 HydrophobicContact CB-CD1 4.44Å; F357-I403 HydrophobicContact CB-CG1 4.33Å
358	Q	96.8	Very high	96.5	Very high	96 Å²	96	40.8 Å²	40.8	45%	0.449	20%	0.199	S	C	.	.	H	α-helix	trans	-63.1	-32.6	179.7	-61.1	-177.2	-76.9	0	0	112.9	V319 H356 R362	V319-Q358 HydrophobicContact CG2-CB 4.08Å; H356-Q358 VanDerWaalsContact C-N 3.33Å; H356-Q358 PolarHBondContact CE1-OE1 2.92Å; H356-Q358 PolarHBondContact ND1-N 2.99Å; H356-Q358 PolarHBondContact O-N 3.47Å; Q358-R362 WeakPolarHBondContact O-CB 3.24Å; Q358-R362 PolarHBondContact O-N 3.09Å
359	V	97.7	Very high	96.4	Very high	0 Å²	0	41.9 Å²	41.9	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-73.5	-47.9	178.2	173.3	0	0	0	0	109.7	E318 V319 L322 C351 H356 F357 R362 A363	E318-V359 HydrophobicContact CB-CG2 4.15Å; E318-V359 HydrophobicContact CG-CG1 3.8Å; E318-V359 HydrophobicContact CG-CG2 4.15Å; V319-V359 HydrophobicContact CG2-CG2 3.91Å; L322-V359 HydrophobicContact CD1-CG1 4.04Å; C351-V359 HydrophobicContact CB-CG1 4.03Å; H356-V359 HydrophobicContact CB-CB 4.41Å; H356-V359 HydrophobicContact CB-CG2 4.21Å; H356-V359 PolarHBondContact O-N 3.44Å; F357-V359 VanDerWaalsContact C-N 3.27Å; F357-V359 PolarHBondContact O-N 3.17Å; V359-R362 PolarHBondContact O-N 2.66Å; V359-A363 WeakPolarHBondContact O-CB 3.29Å; V359-A363 PolarHBondContact O-N 3.07Å
360	A	97.1	Very high	96.4	Very high	0 Å²	0	49.9 Å²	49.9	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-61.8	-46.2	178.6	0	0	0	0	0	111.6	C351 H356 F357 A363 L364 I403	C351-A360 WeakPolarHBondContact O-CA 3.37Å; H356-A360 PolarHBondContact O-N 3.47Å; H356-A360 VanDerWaalsContact O-N 3.17Å; F357-A360 PolarHBondContact O-N 3.21Å; A360-A363 PolarHBondContact O-N 3.13Å; A360-L364 WeakPolarHBondContact O-CB 3.49Å; A360-L364 WeakPolarHBondContact O-CD1 3.22Å; A360-L364 WeakPolarHBondContact O-CG 3.42Å; A360-L364 PolarHBondContact O-N 3.36Å; A360-I403 HydrophobicContact CB-CD1 4.25Å; A360-I403 HydrophobicContact CB-CG2 4.11Å
361	E	97	Very high	96.5	Very high	60 Å²	60	47.4 Å²	47.4	28%	0.28	23%	0.228	S	C	.	.	H	α-helix	trans	-58.4	-52	176	-178	178.8	-159.4	0	0	111.2	F357 A363 L364 Y365 I403 L406	F357-E361 WeakPolarHBondContact O-CB 3.21Å; F357-E361 PolarHBondContact O-N 2.96Å; E361-A363 VanDerWaalsContact C-N 3.27Å; E361-A363 PolarHBondContact O-N 3Å; E361-L364 PolarHBondContact O-N 3.45Å; E361-L364 VanDerWaalsContact O-N 3.08Å; E361-Y365 HydrophobicContact CG-CD2 4.19Å; E361-Y365 HydrophobicContact CG-CE1 4.39Å; E361-Y365 HydrophobicContact CG-CE2 3.48Å; E361-Y365 VanDerWaalsContact CG-CE2 3.48Å; E361-Y365 PolarHBondContact O-N 3.25Å; E361-Y365 PolarHBondContact OE1-OH 2.56Å; E361-I403 HydrophobicContact CB-CD1 3.69Å; E361-L406 HydrophobicContact CG-CD1 4.06Å
362	R	97.8	Very high	96.5	Very high	57 Å²	57	47.4 Å²	47.4	22%	0.215	23%	0.228	C	C	.	.	H	α-helix	trans	-59.2	-38.8	-178.8	-176.9	67.4	-172.1	88.8	-14.6	112.5	V319 L322 E326 Q358 V359	V319-R362 HydrophobicContact CG1-CB 4.33Å; V319-R362 HydrophobicContact CG1-CG 4.07Å; L322-R362 HydrophobicContact CB-CG 3.68Å; L322-R362 HydrophobicContact CD1-CB 4.11Å; L322-R362 HydrophobicContact CD1-CG 4.11Å; E326-R362 IonicContact OE2-CZ 3.31Å; E326-R362 IonicContact OE2-NH1 3.36Å; E326-R362 PolarHBondContact OE2-NH1 3.13Å; E326-R362 IonicContact OE2-NH2 2.74Å; E326-R362 PolarHBondContact OE2-NH2 2.75Å; Q358-R362 WeakPolarHBondContact O-CB 3.24Å; Q358-R362 PolarHBondContact O-N 3.09Å; V359-R362 PolarHBondContact O-N 2.66Å
363	A	97.9	Very high	96.5	Very high	0 Å²	0	49.4 Å²	49.4	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-70.2	-38.6	176.5	0	0	0	0	0	112.1	L322 C351 V352 V359 A360 E361 Y365 Y366 W367	L322-A363 HydrophobicContact CD1-CB 4.05Å; L322-A363 HydrophobicContact CD2-CB 4.11Å; C351-A363 HydrophobicContact CB-CB 3.81Å; V352-A363 HydrophobicContact CG2-CB 3.79Å; V359-A363 WeakPolarHBondContact O-CB 3.29Å; V359-A363 PolarHBondContact O-N 3.07Å; A360-A363 PolarHBondContact O-N 3.13Å; E361-A363 VanDerWaalsContact C-N 3.27Å; E361-A363 PolarHBondContact O-N 3Å; A363-Y365 VanDerWaalsContact C-N 3.27Å; A363-Y365 PolarHBondContact O-N 2.69Å; A363-Y366 WeakPolarHBondContact O-CB 3.28Å; A363-Y366 PolarHBondContact O-N 3.2Å; A363-W367 WeakPolarHBondContact O-CZ3 3.48Å
364	L	97.2	Very high	96.6	Very high	3 Å²	3	50.4 Å²	50.4	2%	0.016	25%	0.246	C	C	.	.	H	α-helix	trans	-68	-24.4	178	-73.5	164.7	0	0	0	113.1	V352 A360 E361 Y366 W367 L391 I403 L406 V407 V410	V352-L364 HydrophobicContact CG1-CD2 3.8Å; V352-L364 HydrophobicContact CG1-CG 4.2Å; V352-L364 HydrophobicContact CG2-CD2 4.11Å; V352-L364 HydrophobicContact CG2-CG 4.22Å; A360-L364 WeakPolarHBondContact O-CB 3.49Å; A360-L364 WeakPolarHBondContact O-CD1 3.22Å; A360-L364 WeakPolarHBondContact O-CG 3.42Å; A360-L364 PolarHBondContact O-N 3.36Å; E361-L364 PolarHBondContact O-N 3.45Å; E361-L364 VanDerWaalsContact O-N 3.08Å; L364-Y366 PolarHBondContact O-N 3.02Å; L364-W367 PolarHBondContact O-N 3.42Å; L364-L391 HydrophobicContact CD2-CD2 4.1Å; L364-I403 HydrophobicContact CD1-CG2 3.9Å; L364-L406 HydrophobicContact CB-CB 4.24Å; L364-L406 HydrophobicContact CB-CD1 4.44Å; L364-L406 HydrophobicContact CD1-CB 3.81Å; L364-L406 HydrophobicContact CD1-CD1 4.43Å; L364-V407 HydrophobicContact CD1-CG2 3.67Å; L364-V407 HydrophobicContact CD2-CG2 3.86Å; L364-V407 HydrophobicContact CG-CG2 4.42Å; L364-V410 HydrophobicContact CD2-CB 4.45Å; L364-V410 HydrophobicContact CD2-CG2 3.81Å
365	Y	96.7	Very high	96.8	Very high	85 Å²	85	49.7 Å²	49.7	33%	0.333	24%	0.24	S	C	.	.	G	3₁₀ helix	trans	-68.2	-12.7	175.1	-71.6	-30.5	0	0	0	114.8	E361 A363 W367 N368 L406	E361-Y365 HydrophobicContact CG-CD2 4.19Å; E361-Y365 HydrophobicContact CG-CE1 4.39Å; E361-Y365 HydrophobicContact CG-CE2 3.48Å; E361-Y365 VanDerWaalsContact CG-CE2 3.48Å; E361-Y365 PolarHBondContact O-N 3.25Å; E361-Y365 PolarHBondContact OE1-OH 2.56Å; A363-Y365 VanDerWaalsContact C-N 3.27Å; A363-Y365 PolarHBondContact O-N 2.69Å; Y365-W367 PolarHBondContact O-N 3.42Å; Y365-W367 VanDerWaalsContact O-N 3.16Å; Y365-N368 WeakPolarHBondContact CD1-ND2 3.38Å; Y365-N368 WeakPolarHBondContact O-CB 3.47Å; Y365-N368 PolarHBondContact O-N 3.14Å; Y365-L406 HydrophobicContact CE1-CD1 4.13Å; Y365-L406 HydrophobicContact CE1-CD2 4.03Å
366	Y	97.6	Very high	97	Very high	2 Å²	2	45 Å²	45	1%	0.008	21%	0.21	C	C	.	.	G	3₁₀ helix	trans	-58.8	-28.7	173.3	-77.8	21.8	0	0	0	112.5	L322 L325 E326 L329 I348 A363 L364 N368 N369 I372	L322-Y366 WeakPolarHBondContact CA-OH 3.23Å; L322-Y366 WeakPolarHBondContact O-CE1 3.39Å; L322-Y366 PolarHBondContact O-OH 3.03Å; L325-Y366 VanDerWaalsContact CB-OH 3.32Å; L325-Y366 WeakPolarHBondContact CB-OH 3.43Å; L325-Y366 HydrophobicContact CD2-CE2 4.29Å; L325-Y366 HydrophobicContact CG-CE2 4.4Å; L325-Y366 WeakPolarHBondContact CG-OH 3.38Å; E326-Y366 HydrophobicContact CB-CD1 4.36Å; E326-Y366 HydrophobicContact CB-CE1 3.74Å; E326-Y366 HydrophobicContact CG-CD1 4.48Å; E326-Y366 HydrophobicContact CG-CE1 4.33Å; E326-Y366 PolarHBondContact N-OH 3.14Å; L329-Y366 HydrophobicContact CD1-CD2 4.29Å; L329-Y366 HydrophobicContact CD1-CE2 3.94Å; I348-Y366 HydrophobicContact CD1-CD2 3.86Å; I348-Y366 HydrophobicContact CD1-CE2 3.76Å; I348-Y366 HydrophobicContact CG1-CE2 4.24Å; A363-Y366 WeakPolarHBondContact O-CB 3.28Å; A363-Y366 PolarHBondContact O-N 3.2Å; L364-Y366 PolarHBondContact O-N 3.02Å; Y366-N368 PolarHBondContact O-N 3.29Å; Y366-N369 PolarHBondContact O-N 2.62Å; Y366-I372 HydrophobicContact CD2-CD1 4.42Å; Y366-I372 HydrophobicContact CG-CD1 4.37Å
367	W	96.7	Very high	97	Very high	21 Å²	21	47.9 Å²	47.9	8%	0.08	22%	0.223	C	C	.	.	G	3₁₀ helix	trans	-75.4	-7.6	177.3	-76.6	-96.9	0	0	0	113.9	I348 V352 A363 L364 Y365 M373 M387 V410 F414	I348-W367 HydrophobicContact CG2-CH2 3.99Å; I348-W367 HydrophobicContact CG2-CZ3 4.24Å; V352-W367 HydrophobicContact CG2-CH2 4.43Å; V352-W367 HydrophobicContact CG2-CZ3 4.22Å; A363-W367 WeakPolarHBondContact O-CZ3 3.48Å; L364-W367 PolarHBondContact O-N 3.42Å; Y365-W367 PolarHBondContact O-N 3.42Å; Y365-W367 VanDerWaalsContact O-N 3.16Å; W367-M373 HydrophobicContact CB-SD 3.93Å; W367-M373 HydrophobicContact CG-SD 3.91Å; W367-M373 VanDerWaalsContact O-CG 3.26Å; W367-M373 WeakPolarHBondContact O-CG 3.42Å; W367-M387 HydrophobicContact CH2-CE 3.55Å; W367-M387 HydrophobicContact CH2-SD 4.42Å; W367-M387 HydrophobicContact CZ2-CE 4.04Å; W367-M387 HydrophobicContact CZ2-CG 4.42Å; W367-V410 HydrophobicContact CB-CG2 3.82Å; W367-V410 HydrophobicContact CD2-CB 4.29Å; W367-V410 HydrophobicContact CD2-CG1 3.64Å; W367-V410 HydrophobicContact CD2-CG2 3.64Å; W367-V410 HydrophobicContact CE3-CG1 4.29Å; W367-V410 HydrophobicContact CE3-CG2 3.92Å; W367-V410 HydrophobicContact CG-CB 4.26Å; W367-V410 HydrophobicContact CG-CG1 3.89Å; W367-V410 HydrophobicContact CG-CG2 3.58Å; W367-V410 HydrophobicContact CZ2-CG1 3.86Å; W367-F414 AromaticContact CE2-CE2 3.7Å; W367-F414 AromaticContact CZ2-CE2 3.66Å; W367-F414 HydrophobicContact CZ2-CE2 3.66Å; W367-F414 AromaticContact CZ2-CZ 3.89Å; W367-F414 HydrophobicContact CZ2-CZ 3.89Å; W367-F414 AromaticContact NE1-CE2 3.27Å; W367-F414 VanDerWaalsContact NE1-CE2 3.27Å; W367-F414 AromaticContact NE1-CZ 3.56Å
368	N	95.4	Very high	97	Very high	119 Å²	119	50.8 Å²	50.8	64%	0.636	24%	0.238	S	C	*	.	G	3₁₀ helix	trans	-88.1	-13.5	172.2	-64.3	-18.3	0	0	0	112.2	Y365 Y366	Y365-N368 WeakPolarHBondContact CD1-ND2 3.38Å; Y365-N368 WeakPolarHBondContact O-CB 3.47Å; Y365-N368 PolarHBondContact O-N 3.14Å; Y366-N368 PolarHBondContact O-N 3.29Å
369	N	96.6	Very high	97	Very high	25 Å²	25	47.3 Å²	47.3	13%	0.134	22%	0.223	C	C	.	.			trans	-85.3	116	-179.8	-176.1	-48.7	0	0	0	109.7	E326 D330 Y366 Y371 I372 M373	E326-N369 PolarHBondContact OE1-ND2 3.28Å; D330-N369 PolarHBondContact OD1-ND2 3.42Å; D330-N369 PolarHBondContact OD1-OD1 3.05Å; Y366-N369 PolarHBondContact O-N 2.62Å; N369-Y371 VanDerWaalsContact C-N 3.3Å; N369-Y371 PolarHBondContact O-N 3.23Å; N369-Y371 PolarHBondContact OD1-N 3.49Å; N369-I372 HydrophobicContact CB-CB 4.09Å; N369-I372 HydrophobicContact CB-CD1 4Å; N369-I372 HydrophobicContact CB-CG1 4.1Å; N369-I372 PolarHBondContact O-N 3.47Å; N369-I372 PolarHBondContact OD1-N 3.01Å; N369-I372 VanDerWaalsContact OD1-N 3.17Å; N369-M373 WeakPolarHBondContact O-CB 3.39Å; N369-M373 WeakPolarHBondContact O-CG 3.18Å; N369-M373 PolarHBondContact O-N 3.07Å
370	E	96.9	Very high	96.9	Very high	173 Å²	173	47.9 Å²	47.9	81%	0.808	23%	0.227	S	C	*	.	H	α-helix	trans	-60.5	-37.7	-175	-65.1	-174	170.5	0	0	112.7	M373 S374	E370-M373 PolarHBondContact O-N 2.97Å; E370-S374 PolarHBondContact O-N 2.96Å
371	Y	98	Very high	96.8	Very high	79 Å²	79	53 Å²	53	31%	0.31	25%	0.254	S	S	.	.	H	α-helix	trans	-72	-45.9	-179	-174.4	-120.4	0	0	0	111.3	L329 I332 N369 M373 S374 L375	L329-Y371 VanDerWaalsContact O-CD1 3.29Å; L329-Y371 WeakPolarHBondContact O-CD1 3.38Å; L329-Y371 VanDerWaalsContact O-CE1 3.22Å; L329-Y371 WeakPolarHBondContact O-CE1 3.42Å; I332-Y371 HydrophobicContact CG2-CE1 4.25Å; I332-Y371 PolarHBondContact O-OH 3.04Å; N369-Y371 VanDerWaalsContact C-N 3.3Å; N369-Y371 PolarHBondContact O-N 3.23Å; N369-Y371 PolarHBondContact OD1-N 3.49Å; Y371-M373 VanDerWaalsContact C-N 3.27Å; Y371-M373 PolarHBondContact O-N 3.32Å; Y371-S374 PolarHBondContact O-N 3.11Å; Y371-S374 VanDerWaalsContact O-N 3.13Å; Y371-S374 PolarHBondContact O-OG 3.44Å; Y371-L375 HydrophobicContact CD1-CD1 4.19Å; Y371-L375 HydrophobicContact CE1-CD1 3.85Å; Y371-L375 HydrophobicContact CE1-CG 4.46Å; Y371-L375 PolarHBondContact O-N 2.96Å; Y371-L375 VanDerWaalsContact O-N 3.09Å
372	I	97.7	Very high	96.7	Very high	0 Å²	0	52.6 Å²	52.6	0%	0	26%	0.255	C	S	.	.	H	α-helix	trans	-58.5	-42.4	174	-63.2	-179.9	0	0	0	110.6	E326 L329 Y366 N369 S374 L375 I376	E326-I372 HydrophobicContact CG-CD1 3.88Å; L329-I372 HydrophobicContact CB-CD1 3.85Å; L329-I372 HydrophobicContact CB-CG1 3.92Å; L329-I372 HydrophobicContact CD1-CD1 3.94Å; L329-I372 HydrophobicContact CD1-CG1 4.41Å; Y366-I372 HydrophobicContact CD2-CD1 4.42Å; Y366-I372 HydrophobicContact CG-CD1 4.37Å; N369-I372 HydrophobicContact CB-CB 4.09Å; N369-I372 HydrophobicContact CB-CD1 4Å; N369-I372 HydrophobicContact CB-CG1 4.1Å; N369-I372 PolarHBondContact O-N 3.47Å; N369-I372 PolarHBondContact OD1-N 3.01Å; N369-I372 VanDerWaalsContact OD1-N 3.17Å; I372-S374 VanDerWaalsContact C-N 3.34Å; I372-S374 PolarHBondContact O-N 3.46Å; I372-L375 PolarHBondContact O-N 3.37Å; I372-I376 HydrophobicContact CG2-CD1 3.79Å; I372-I376 HydrophobicContact CG2-CG1 4.34Å; I372-I376 VanDerWaalsContact O-CG1 3.28Å; I372-I376 WeakPolarHBondContact O-CG1 3.36Å; I372-I376 PolarHBondContact O-N 3.15Å
373	M	96.6	Very high	96.7	Very high	43 Å²	43	49.9 Å²	49.9	21%	0.212	25%	0.245	C	C	.	.	H	α-helix	trans	-59.9	-42.5	175.9	-78.6	-59.1	-60.6	0	0	112.4	W367 N369 E370 Y371 L375 I376 E377 A413	W367-M373 HydrophobicContact CB-SD 3.93Å; W367-M373 HydrophobicContact CG-SD 3.91Å; W367-M373 VanDerWaalsContact O-CG 3.26Å; W367-M373 WeakPolarHBondContact O-CG 3.42Å; N369-M373 WeakPolarHBondContact O-CB 3.39Å; N369-M373 WeakPolarHBondContact O-CG 3.18Å; N369-M373 PolarHBondContact O-N 3.07Å; E370-M373 PolarHBondContact O-N 2.97Å; Y371-M373 VanDerWaalsContact C-N 3.27Å; Y371-M373 PolarHBondContact O-N 3.32Å; M373-L375 VanDerWaalsContact C-N 3.35Å; M373-L375 PolarHBondContact O-N 3.03Å; M373-I376 PolarHBondContact O-N 3.01Å; M373-I376 HydrophobicContact SD-CD1 4.39Å; M373-E377 PolarHBondContact O-N 3.36Å; M373-A413 HydrophobicContact CE-CB 4.18Å
374	S	97.2	Very high	96.6	Very high	41 Å²	41	49.9 Å²	49.9	29%	0.287	25%	0.245	S	C	.	.	H	α-helix	trans	-60.8	-41.8	176.1	77.1	0	0	0	0	112.5	E370 Y371 I372 I376 E377 E378	E370-S374 PolarHBondContact O-N 2.96Å; Y371-S374 PolarHBondContact O-N 3.11Å; Y371-S374 VanDerWaalsContact O-N 3.13Å; Y371-S374 PolarHBondContact O-OG 3.44Å; I372-S374 VanDerWaalsContact C-N 3.34Å; I372-S374 PolarHBondContact O-N 3.46Å; S374-I376 VanDerWaalsContact C-N 3.34Å; S374-I376 PolarHBondContact O-N 3.1Å; S374-E377 PolarHBondContact O-N 3.28Å; S374-E378 PolarHBondContact O-N 3.42Å; S374-E378 VanDerWaalsContact O-N 3.14Å
375	L	97.7	Very high	96.5	Very high	2 Å²	2	52.1 Å²	52.1	1%	0.01	26%	0.26	C	S	.	.	H	α-helix	trans	-66.1	-37.1	176.4	-67.1	172.8	0	0	0	112	I332 P334 F337 Y371 I372 M373 N379	I332-L375 HydrophobicContact CG2-CD1 3.61Å; P334-L375 HydrophobicContact CB-CD2 4.06Å; P334-L375 HydrophobicContact CG-CD2 3.95Å; F337-L375 HydrophobicContact CD1-CB 4.14Å; F337-L375 HydrophobicContact CD1-CD2 4.4Å; F337-L375 HydrophobicContact CD2-CD1 4.05Å; F337-L375 HydrophobicContact CE1-CB 3.87Å; F337-L375 HydrophobicContact CE2-CB 4.28Å; F337-L375 HydrophobicContact CE2-CD1 4.32Å; F337-L375 HydrophobicContact CG-CB 4.45Å; F337-L375 HydrophobicContact CG-CD1 4.25Å; F337-L375 HydrophobicContact CG-CD2 4.41Å; F337-L375 HydrophobicContact CZ-CB 3.92Å; Y371-L375 HydrophobicContact CD1-CD1 4.19Å; Y371-L375 HydrophobicContact CE1-CD1 3.85Å; Y371-L375 HydrophobicContact CE1-CG 4.46Å; Y371-L375 PolarHBondContact O-N 2.96Å; Y371-L375 VanDerWaalsContact O-N 3.09Å; I372-L375 PolarHBondContact O-N 3.37Å; M373-L375 VanDerWaalsContact C-N 3.35Å; M373-L375 PolarHBondContact O-N 3.03Å; L375-N379 WeakPolarHBondContact O-CB 3.34Å; L375-N379 PolarHBondContact O-N 3.42Å; L375-N379 PolarHBondContact O-ND2 2.92Å
376	I	97.1	Very high	96.5	Very high	1 Å²	1	49.5 Å²	49.5	1%	0.005	25%	0.251	C	S	.	.	H	α-helix	trans	-66.3	-40.5	175.7	-69.2	168.8	0	0	0	110.8	F345 I372 M373 S374 N379 S380 I383 F414 M417	F345-I376 HydrophobicContact CE1-CD1 3.91Å; F345-I376 HydrophobicContact CE1-CG1 4.03Å; F345-I376 HydrophobicContact CZ-CD1 3.84Å; F345-I376 HydrophobicContact CZ-CG1 3.59Å; I372-I376 HydrophobicContact CG2-CD1 3.79Å; I372-I376 HydrophobicContact CG2-CG1 4.34Å; I372-I376 VanDerWaalsContact O-CG1 3.28Å; I372-I376 WeakPolarHBondContact O-CG1 3.36Å; I372-I376 PolarHBondContact O-N 3.15Å; M373-I376 PolarHBondContact O-N 3.01Å; M373-I376 HydrophobicContact SD-CD1 4.39Å; S374-I376 VanDerWaalsContact C-N 3.34Å; S374-I376 PolarHBondContact O-N 3.1Å; I376-N379 CarbonylContact O-C 3.51Å; I376-N379 VanDerWaalsContact O-C 3.32Å; I376-N379 PolarHBondContact O-N 3.22Å; I376-S380 VanDerWaalsContact O-CA 3.24Å; I376-S380 WeakPolarHBondContact O-CA 3.21Å; I376-S380 PolarHBondContact O-N 3.06Å; I376-I383 HydrophobicContact CB-CD1 4.36Å; I376-I383 HydrophobicContact CG1-CD1 4.12Å; I376-I383 HydrophobicContact CG2-CG2 4.15Å; I376-F414 HydrophobicContact CG2-CE1 3.81Å; I376-F414 HydrophobicContact CG2-CZ 4.2Å; I376-M417 HydrophobicContact CG2-CE 3.61Å; I376-M417 HydrophobicContact CG2-SD 3.97Å
377	E	95.8	Very high	96.4	Very high	123 Å²	123	49.4 Å²	49.4	58%	0.575	25%	0.251	S	S	*	.	H	α-helix	trans	-62.8	-49.8	179	-178.7	168.1	-165.8	0	0	112.3	M373 S374 N379 S380 M417	M373-E377 PolarHBondContact O-N 3.36Å; S374-E377 PolarHBondContact O-N 3.28Å; E377-N379 PolarHBondContact O-N 3.35Å; E377-N379 VanDerWaalsContact O-N 3.16Å; E377-S380 WeakPolarHBondContact O-CB 3.4Å; E377-S380 PolarHBondContact O-N 3.47Å; E377-S380 PolarHBondContact O-OG 3.46Å; E377-M417 WeakPolarHBondContact CA-SD 3.46Å; E377-M417 HydrophobicContact CB-CG 4.08Å; E377-M417 HydrophobicContact CB-SD 3.73Å; E377-M417 HydrophobicContact CG-CG 3.88Å; E377-M417 HydrophobicContact CG-SD 4.22Å
378	E	95.8	Very high	96.3	Very high	136 Å²	136	48.7 Å²	48.7	64%	0.636	25%	0.248	S	C	*	.	H	α-helix	trans	-60.2	-27.2	176.5	-69.4	-177	-179.6	0	0	113.1	S374	S374-E378 PolarHBondContact O-N 3.42Å; S374-E378 VanDerWaalsContact O-N 3.14Å
379	N	96.6	Very high	96.2	Very high	24 Å²	24	45.7 Å²	45.7	13%	0.128	24%	0.237	C	C	.	.	T	Hydrogen-bonded Turn	trans	-116.9	22.3	-175.4	-62.9	-85.2	0	0	0	113.7	F337 L375 I376 E377 N381 V382 I383	F337-N379 HydrophobicContact CE1-CB 4.22Å; L375-N379 WeakPolarHBondContact O-CB 3.34Å; L375-N379 PolarHBondContact O-N 3.42Å; L375-N379 PolarHBondContact O-ND2 2.92Å; I376-N379 CarbonylContact O-C 3.51Å; I376-N379 VanDerWaalsContact O-C 3.32Å; I376-N379 PolarHBondContact O-N 3.22Å; E377-N379 PolarHBondContact O-N 3.35Å; E377-N379 VanDerWaalsContact O-N 3.16Å; N379-N381 PolarHBondContact O-N 3.05Å; N379-N381 VanDerWaalsContact O-N 3.13Å; N379-V382 PolarHBondContact O-N 3.19Å; N379-I383 HydrophobicContact CB-CD1 3.8Å; N379-I383 HydrophobicContact CB-CG1 4.46Å; N379-I383 PolarHBondContact O-N 3.22Å; N379-I383 VanDerWaalsContact O-N 3.16Å
380	S	95	Very high	96.1	Very high	12 Å²	12	45.2 Å²	45.2	8%	0.084	24%	0.235	C	C	.	.	H	α-helix	trans	-54.8	-38.2	-172.7	60.2	0	0	0	0	112.9	I376 E377 V382 I383 L384 N418	I376-S380 VanDerWaalsContact O-CA 3.24Å; I376-S380 WeakPolarHBondContact O-CA 3.21Å; I376-S380 PolarHBondContact O-N 3.06Å; E377-S380 WeakPolarHBondContact O-CB 3.4Å; E377-S380 PolarHBondContact O-N 3.47Å; E377-S380 PolarHBondContact O-OG 3.46Å; S380-V382 PolarHBondContact O-N 3.31Å; S380-V382 VanDerWaalsContact O-N 3.13Å; S380-I383 PolarHBondContact O-N 3.01Å; S380-L384 WeakPolarHBondContact O-CB 3.39Å; S380-L384 PolarHBondContact O-N 2.93Å; S380-N418 PolarHBondContact OG-ND2 3.44Å
381	N	94.6	Very high	96	Very high	107 Å²	107	37 Å²	37	57%	0.572	20%	0.197	S	C	*	.	H	α-helix	trans	-58.4	-25.8	179.3	-65.6	-34.4	0	0	0	114.1	N379 N418 M421	N379-N381 PolarHBondContact O-N 3.05Å; N379-N381 VanDerWaalsContact O-N 3.13Å; N381-N418 PolarHBondContact OD1-ND2 3.47Å; N381-M421 WeakPolarHBondContact O-CE 3.47Å
382	V	96.5	Very high	95.7	Very high	51 Å²	51	35.1 Å²	35.1	31%	0.309	19%	0.19	S	C	.	.	H	α-helix	trans	-98.5	-43	178.8	-179.3	0	0	0	0	110.8	Q341 E342 N379 S380 I386	Q341-V382 HydrophobicContact CG-CG1 4.32Å; E342-V382 HydrophobicContact CG-CG1 3.71Å; N379-V382 PolarHBondContact O-N 3.19Å; S380-V382 PolarHBondContact O-N 3.31Å; S380-V382 VanDerWaalsContact O-N 3.13Å; V382-I386 HydrophobicContact CG1-CD1 4.33Å; V382-I386 WeakPolarHBondContact O-CD1 3.4Å; V382-I386 WeakPolarHBondContact O-CG1 3.28Å
383	I	96.9	Very high	95.4	Very high	0 Å²	0	39.9 Å²	39.9	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-76.8	-43.1	-170.9	-67.9	166.9	0	0	0	112.1	F337 F345 I376 N379 S380 I386 M387 F414	F337-I383 HydrophobicContact CE1-CD1 3.86Å; F337-I383 HydrophobicContact CZ-CD1 3.74Å; F345-I383 HydrophobicContact CD1-CG2 3.49Å; F345-I383 VanDerWaalsContact CD1-CG2 3.49Å; F345-I383 HydrophobicContact CD2-CD1 4.07Å; F345-I383 HydrophobicContact CD2-CG1 3.89Å; F345-I383 HydrophobicContact CD2-CG2 4.29Å; F345-I383 HydrophobicContact CE1-CG2 3.62Å; F345-I383 HydrophobicContact CE2-CD1 3.71Å; F345-I383 HydrophobicContact CE2-CG1 4.06Å; F345-I383 HydrophobicContact CE2-CG2 4.42Å; F345-I383 HydrophobicContact CG-CG1 4.19Å; F345-I383 HydrophobicContact CG-CG2 3.85Å; F345-I383 HydrophobicContact CZ-CD1 4Å; F345-I383 HydrophobicContact CZ-CG1 4.47Å; F345-I383 HydrophobicContact CZ-CG2 4.1Å; I376-I383 HydrophobicContact CB-CD1 4.36Å; I376-I383 HydrophobicContact CG1-CD1 4.12Å; I376-I383 HydrophobicContact CG2-CG2 4.15Å; N379-I383 HydrophobicContact CB-CD1 3.8Å; N379-I383 HydrophobicContact CB-CG1 4.46Å; N379-I383 PolarHBondContact O-N 3.22Å; N379-I383 VanDerWaalsContact O-N 3.16Å; S380-I383 PolarHBondContact O-N 3.01Å; I383-I386 WeakPolarHBondContact O-CB 3.49Å; I383-I386 PolarHBondContact O-N 2.87Å; I383-I386 VanDerWaalsContact O-N 3.14Å; I383-M387 HydrophobicContact CG2-CG 4.11Å; I383-M387 PolarHBondContact O-N 2.9Å; I383-M387 VanDerWaalsContact O-N 3.07Å; I383-F414 HydrophobicContact CG2-CE1 4.29Å; I383-F414 HydrophobicContact CG2-CZ 4.22Å
384	L	95.4	Very high	95.2	Very high	1 Å²	1	38.4 Å²	38.4	1%	0.005	20%	0.2	C	C	.	.	H	α-helix	trans	-59.4	-48.4	-176	172	59.2	0	0	0	112	S380 I386 M387 F388 F414 N418 M421 F422 L425	S380-L384 WeakPolarHBondContact O-CB 3.39Å; S380-L384 PolarHBondContact O-N 2.93Å; L384-I386 PolarHBondContact O-N 3.37Å; L384-M387 PolarHBondContact O-N 3.05Å; L384-F388 HydrophobicContact CD1-CB 4.34Å; L384-F388 HydrophobicContact CD1-CD2 4.23Å; L384-F388 VanDerWaalsContact O-CB 3.23Å; L384-F388 WeakPolarHBondContact O-CB 3.09Å; L384-F388 PolarHBondContact O-N 3.27Å; L384-F414 HydrophobicContact CB-CD1 4.01Å; L384-F414 HydrophobicContact CB-CE1 4.08Å; L384-F414 HydrophobicContact CD1-CB 3.82Å; L384-F414 HydrophobicContact CD1-CD1 3.51Å; L384-F414 HydrophobicContact CD1-CD2 4.37Å; L384-F414 HydrophobicContact CD1-CE1 4.13Å; L384-F414 HydrophobicContact CD1-CG 3.66Å; L384-F414 HydrophobicContact CG-CD1 4.21Å; L384-N418 HydrophobicContact CD2-CB 4.34Å; L384-M421 HydrophobicContact CB-SD 4.23Å; L384-M421 HydrophobicContact CD2-CB 3.96Å; L384-M421 HydrophobicContact CD2-CG 3.78Å; L384-M421 HydrophobicContact CD2-SD 4.02Å; L384-M421 HydrophobicContact CG-CG 4.39Å; L384-M421 HydrophobicContact CG-SD 4.34Å; L384-F422 HydrophobicContact CD1-CD2 4.28Å; L384-F422 HydrophobicContact CD2-CB 4.39Å; L384-L425 HydrophobicContact CD1-CD1 4.3Å; L384-L425 HydrophobicContact CD2-CD1 4.18Å; L384-L425 HydrophobicContact CG-CD1 3.65Å
385	P	95.5	Very high	94.9	Very high	50 Å²	50	36.8 Å²	36.8	33%	0.325	19%	0.189	S	C	.	.	H	α-helix	trans	-57.7	-32.4	176.2	-26.6	35.5	0	0	0	114.5	M421 L425	P385-M421 HydrophobicContact CG-CE 3.65Å; P385-M421 HydrophobicContact CG-SD 3.78Å; P385-L425 HydrophobicContact CB-CD1 4.37Å; P385-L425 HydrophobicContact CB-CD2 4.21Å; P385-L425 HydrophobicContact CG-CD1 4.18Å; P385-L425 HydrophobicContact CG-CD2 4.49Å
386	I	96.7	Very high	94.5	Very high	30 Å²	30	41.9 Å²	41.9	15%	0.154	21%	0.211	C	C	.	.	H	α-helix	trans	-71.2	-46.9	178.9	-63.9	169.9	0	0	0	110.4	E342 F345 K346 V382 I383 L384	E342-I386 HydrophobicContact CB-CD1 4.47Å; E342-I386 HydrophobicContact CG-CD1 4.17Å; F345-I386 HydrophobicContact CB-CG2 4.07Å; K346-I386 HydrophobicContact CB-CG2 4.46Å; K346-I386 HydrophobicContact CG-CG2 3.82Å; V382-I386 HydrophobicContact CG1-CD1 4.33Å; V382-I386 WeakPolarHBondContact O-CD1 3.4Å; V382-I386 WeakPolarHBondContact O-CG1 3.28Å; I383-I386 WeakPolarHBondContact O-CB 3.49Å; I383-I386 PolarHBondContact O-N 2.87Å; I383-I386 VanDerWaalsContact O-N 3.14Å; L384-I386 PolarHBondContact O-N 3.37Å
387	M	96.7	Very high	94.1	Very high	0 Å²	0	48.1 Å²	48.1	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-79.1	-33.7	-174	-68.8	-56.7	-51.2	0	0	113.4	F345 I348 A349 V352 W367 I383 L384 S389 S390 L391 F414	F345-M387 HydrophobicContact CB-SD 4.31Å; F345-M387 HydrophobicContact CD1-CG 3.86Å; F345-M387 HydrophobicContact CD1-SD 3.85Å; I348-M387 HydrophobicContact CB-SD 4.45Å; I348-M387 HydrophobicContact CG2-CE 4.19Å; I348-M387 HydrophobicContact CG2-SD 4.28Å; A349-M387 HydrophobicContact CB-CE 4.14Å; A349-M387 HydrophobicContact CB-SD 3.68Å; V352-M387 HydrophobicContact CG2-CE 4.13Å; W367-M387 HydrophobicContact CH2-CE 3.55Å; W367-M387 HydrophobicContact CH2-SD 4.42Å; W367-M387 HydrophobicContact CZ2-CE 4.04Å; W367-M387 HydrophobicContact CZ2-CG 4.42Å; I383-M387 HydrophobicContact CG2-CG 4.11Å; I383-M387 PolarHBondContact O-N 2.9Å; I383-M387 VanDerWaalsContact O-N 3.07Å; L384-M387 PolarHBondContact O-N 3.05Å; M387-S389 PolarHBondContact O-N 3.34Å; M387-S390 PolarHBondContact O-N 3.09Å; M387-S390 VanDerWaalsContact O-N 3.09Å; M387-L391 HydrophobicContact CB-CD1 3.9Å; M387-L391 HydrophobicContact CE-CD1 4.44Å; M387-L391 HydrophobicContact CE-CG 4.34Å; M387-L391 PolarHBondContact O-N 2.92Å; M387-F414 HydrophobicContact CB-CE2 4.28Å; M387-F414 HydrophobicContact CB-CZ 4.19Å; M387-F414 HydrophobicContact CG-CZ 4.32Å
388	F	94.8	Very high	93.9	Very high	5 Å²	5	43.3 Å²	43.3	2%	0.022	22%	0.218	C	C	.	.	H	α-helix	trans	-53.3	-50.6	-168.2	-176.5	-89.5	0	0	0	113.1	L384 S390 L391 Y392 F422 L425 T426 Y429	L384-F388 HydrophobicContact CD1-CB 4.34Å; L384-F388 HydrophobicContact CD1-CD2 4.23Å; L384-F388 VanDerWaalsContact O-CB 3.23Å; L384-F388 WeakPolarHBondContact O-CB 3.09Å; L384-F388 PolarHBondContact O-N 3.27Å; F388-S390 PolarHBondContact O-N 2.86Å; F388-L391 PolarHBondContact O-N 2.96Å; F388-Y392 HydrophobicContact CE1-CD2 4.47Å; F388-Y392 HydrophobicContact CE1-CG 4.29Å; F388-Y392 AromaticContact CZ-CD2 4Å; F388-Y392 HydrophobicContact CZ-CD2 4Å; F388-Y392 HydrophobicContact CZ-CG 4.27Å; F388-Y392 VanDerWaalsContact O-CB 3.3Å; F388-Y392 WeakPolarHBondContact O-CB 3.35Å; F388-Y392 PolarHBondContact O-N 2.87Å; F388-F422 HydrophobicContact CD2-CD2 4.22Å; F388-F422 HydrophobicContact CD2-CE2 4.14Å; F388-F422 HydrophobicContact CE2-CD1 4.49Å; F388-F422 HydrophobicContact CE2-CD2 4.03Å; F388-F422 HydrophobicContact CE2-CE1 4.28Å; F388-F422 AromaticContact CE2-CE2 3.81Å; F388-F422 HydrophobicContact CE2-CE2 3.81Å; F388-F422 HydrophobicContact CE2-CG 4.37Å; F388-F422 AromaticContact CE2-CZ 3.94Å; F388-F422 HydrophobicContact CE2-CZ 3.94Å; F388-L425 HydrophobicContact CB-CD1 4Å; F388-L425 HydrophobicContact CD1-CB 3.84Å; F388-L425 HydrophobicContact CD2-CB 4.02Å; F388-L425 HydrophobicContact CD2-CD1 4.32Å; F388-L425 HydrophobicContact CE1-CB 4.06Å; F388-L425 WeakPolarHBondContact CE1-O 3.47Å; F388-L425 HydrophobicContact CE2-CB 4.21Å; F388-L425 HydrophobicContact CG-CB 3.85Å; F388-L425 HydrophobicContact CG-CD1 4.13Å; F388-L425 HydrophobicContact CZ-CB 4.25Å; F388-T426 WeakPolarHBondContact CZ-OG1 3.24Å; F388-Y429 HydrophobicContact CE1-CD2 4.35Å; F388-Y429 HydrophobicContact CE1-CG 4.2Å
389	S	92.3	Very high	93.8	Very high	57 Å²	57	45.1 Å²	45.1	40%	0.399	22%	0.219	S	C	.	.	H	α-helix	trans	-60	-34.8	-176.9	64.8	0	0	0	0	113.4	M387 R393	M387-S389 PolarHBondContact O-N 3.34Å; S389-R393 WeakPolarHBondContact O-CB 3.49Å; S389-R393 PolarHBondContact O-N 3.38Å
390	S	94	Very high	93.7	Very high	14 Å²	14	45.3 Å²	45.3	10%	0.098	22%	0.22	C	C	.	.	H	α-helix	trans	-75.7	-50.7	179.6	-67.7	0	0	0	0	110.5	A349 S353 M387 F388 Y392 R393 I394	A349-S390 PolarHBondContact O-OG 3.27Å; S353-S390 VanDerWaalsContact OG-CB 3.28Å; S353-S390 WeakPolarHBondContact OG-CB 3.2Å; S353-S390 PolarHBondContact OG-OG 3.28Å; M387-S390 PolarHBondContact O-N 3.09Å; M387-S390 VanDerWaalsContact O-N 3.09Å; F388-S390 PolarHBondContact O-N 2.86Å; S390-Y392 PolarHBondContact O-N 3.42Å; S390-R393 PolarHBondContact O-N 3.38Å; S390-I394 VanDerWaalsContact O-CG1 3.24Å; S390-I394 WeakPolarHBondContact O-CG1 3.35Å; S390-I394 PolarHBondContact O-N 2.96Å
391	L	95	Very high	93.6	Very high	0 Å²	0	49.5 Å²	49.5	0%	0	25%	0.247	C	C	.	.	H	α-helix	trans	-59.1	-46.4	178.6	-68.6	165.6	0	0	0	112.1	V352 L364 M387 F388 R393 I394 S395 V407 V410 L411 F414	V352-L391 HydrophobicContact CG1-CD2 3.79Å; L364-L391 HydrophobicContact CD2-CD2 4.1Å; M387-L391 HydrophobicContact CB-CD1 3.9Å; M387-L391 HydrophobicContact CE-CD1 4.44Å; M387-L391 HydrophobicContact CE-CG 4.34Å; M387-L391 PolarHBondContact O-N 2.92Å; F388-L391 PolarHBondContact O-N 2.96Å; L391-R393 VanDerWaalsContact C-N 3.3Å; L391-R393 PolarHBondContact O-N 3.17Å; L391-I394 PolarHBondContact O-N 2.94Å; L391-S395 PolarHBondContact O-N 2.99Å; L391-S395 PolarHBondContact O-OG 2.92Å; L391-V407 HydrophobicContact CB-CG1 4.17Å; L391-V407 HydrophobicContact CD2-CG1 3.99Å; L391-V407 HydrophobicContact CD2-CG2 4.44Å; L391-V407 VanDerWaalsContact O-CG1 3.22Å; L391-V407 WeakPolarHBondContact O-CG1 3.22Å; L391-V410 HydrophobicContact CD1-CG1 3.69Å; L391-V410 HydrophobicContact CD2-CB 4.25Å; L391-V410 HydrophobicContact CD2-CG1 3.73Å; L391-V410 HydrophobicContact CG-CG1 4.39Å; L391-L411 HydrophobicContact CB-CD2 3.67Å; L391-L411 HydrophobicContact CB-CG 4.08Å; L391-L411 HydrophobicContact CD1-CD2 4.32Å; L391-F414 HydrophobicContact CD1-CD2 3.83Å; L391-F414 HydrophobicContact CD1-CE2 3.64Å
392	Y	92	Very high	93.7	Very high	41 Å²	41	47.1 Å²	47.1	16%	0.161	24%	0.242	C	C	.	.	H	α-helix	trans	-67.7	-28.7	-177.7	-164.7	-95.5	0	0	0	113.4	F388 S390 S395 K396 Y429	F388-Y392 HydrophobicContact CE1-CD2 4.47Å; F388-Y392 HydrophobicContact CE1-CG 4.29Å; F388-Y392 AromaticContact CZ-CD2 4Å; F388-Y392 HydrophobicContact CZ-CD2 4Å; F388-Y392 HydrophobicContact CZ-CG 4.27Å; F388-Y392 VanDerWaalsContact O-CB 3.3Å; F388-Y392 WeakPolarHBondContact O-CB 3.35Å; F388-Y392 PolarHBondContact O-N 2.87Å; S390-Y392 PolarHBondContact O-N 3.42Å; Y392-S395 PolarHBondContact O-OG 3.02Å; Y392-K396 HydrophobicContact CE1-CD 4.37Å; Y392-K396 VanDerWaalsContact CZ-NZ 3.25Å; Y392-K396 PolarHBondContact OH-NZ 3.37Å; Y392-Y429 AromaticContact CD1-CD1 3.55Å; Y392-Y429 HydrophobicContact CD1-CD1 3.55Å; Y392-Y429 AromaticContact CD1-CE1 3.36Å; Y392-Y429 HydrophobicContact CD1-CE1 3.36Å; Y392-Y429 HydrophobicContact CD1-CE2 4.49Å; Y392-Y429 HydrophobicContact CD1-CG 4.23Å; Y392-Y429 AromaticContact CD1-CZ 3.86Å; Y392-Y429 AromaticContact CE1-CD1 3.71Å; Y392-Y429 HydrophobicContact CE1-CD1 3.71Å; Y392-Y429 AromaticContact CE1-CE1 3.71Å; Y392-Y429 HydrophobicContact CE1-CE1 3.71Å; Y392-Y429 HydrophobicContact CG-CE1 4.5Å
393	R	91.4	Very high	93.6	Very high	99 Å²	99	44.8 Å²	44.8	37%	0.374	23%	0.228	S	C	.	.	H	α-helix	trans	-72.3	-50.6	172.4	-179.3	-177.2	58.4	-169.6	-4.9	111	S353 S389 S390 L391 S395 K396 E397	S353-R393 PolarHBondContact OG-NH2 3.4Å; S389-R393 WeakPolarHBondContact O-CB 3.49Å; S389-R393 PolarHBondContact O-N 3.38Å; S390-R393 PolarHBondContact O-N 3.38Å; L391-R393 VanDerWaalsContact C-N 3.3Å; L391-R393 PolarHBondContact O-N 3.17Å; R393-S395 VanDerWaalsContact C-N 3.3Å; R393-S395 PolarHBondContact O-N 3.48Å; R393-K396 PolarHBondContact O-N 3.42Å; R393-E397 HydrophobicContact CG-CG 4.49Å; R393-E397 WeakPolarHBondContact CG-OE2 3.48Å; R393-E397 PolarHBondContact O-N 3.44Å; R393-E397 VanDerWaalsContact O-N 3.07Å
394	I	91.9	Very high	93.6	Very high	12 Å²	12	46.1 Å²	46.1	6%	0.062	24%	0.236	C	C	.	.	H	α-helix	trans	-65.2	-33.3	-175.2	-63	-61	0	0	0	111.7	S390 L391 K396 E397 H398 I403 V407	S390-I394 VanDerWaalsContact O-CG1 3.24Å; S390-I394 WeakPolarHBondContact O-CG1 3.35Å; S390-I394 PolarHBondContact O-N 2.96Å; L391-I394 PolarHBondContact O-N 2.94Å; I394-K396 PolarHBondContact O-N 3.36Å; I394-K396 VanDerWaalsContact O-N 3.12Å; I394-E397 PolarHBondContact O-N 3.29Å; I394-H398 HydrophobicContact CG2-CB 3.72Å; I394-H398 VanDerWaalsContact O-CB 3.24Å; I394-H398 WeakPolarHBondContact O-CB 3.24Å; I394-H398 PolarHBondContact O-N 3.16Å; I394-H398 VanDerWaalsContact O-N 3.11Å; I394-I403 HydrophobicContact CG2-CG2 4.18Å; I394-V407 HydrophobicContact CB-CG2 4.42Å; I394-V407 HydrophobicContact CG2-CG2 3.78Å
395	S	91.7	Very high	93.6	Very high	8 Å²	8	48.5 Å²	48.5	6%	0.056	26%	0.256	C	S	.	.	H	α-helix	trans	-60.9	-20.2	173.9	67.1	0	0	0	0	114	L391 Y392 R393	L391-S395 PolarHBondContact O-N 2.99Å; L391-S395 PolarHBondContact O-OG 2.92Å; Y392-S395 PolarHBondContact O-OG 3.02Å; R393-S395 VanDerWaalsContact C-N 3.3Å; R393-S395 PolarHBondContact O-N 3.48Å
396	K	89	Confident	93.6	Very high	108 Å²	108	47.7 Å²	47.7	47%	0.47	25%	0.249	S	C	.	.	H	α-helix	trans	-105.2	-28.6	-179.4	-61.3	-173.4	-177.2	-172	0	113.9	Y392 R393 I394	Y392-K396 HydrophobicContact CE1-CD 4.37Å; Y392-K396 VanDerWaalsContact CZ-NZ 3.25Å; Y392-K396 PolarHBondContact OH-NZ 3.37Å; R393-K396 PolarHBondContact O-N 3.42Å; I394-K396 PolarHBondContact O-N 3.36Å; I394-K396 VanDerWaalsContact O-N 3.12Å
397	E	89.4	Confident	93.6	Very high	132 Å²	132	46.3 Å²	46.3	62%	0.617	24%	0.241	S	C	*	.	H	α-helix	trans	-117.4	-12	-164.1	-66.1	173.4	-167.5	0	0	114	R393 I394	R393-E397 HydrophobicContact CG-CG 4.49Å; R393-E397 WeakPolarHBondContact CG-OE2 3.48Å; R393-E397 PolarHBondContact O-N 3.44Å; R393-E397 VanDerWaalsContact O-N 3.07Å; I394-E397 PolarHBondContact O-N 3.29Å
398	H	89.9	Confident	93.5	Very high	22 Å²	22	52.2 Å²	52.2	10%	0.102	27%	0.265	C	S	.	.			trans	-73	134.1	-175.5	-161.5	-83.8	0	0	0	112.2	I394 N400 V404	I394-H398 HydrophobicContact CG2-CB 3.72Å; I394-H398 VanDerWaalsContact O-CB 3.24Å; I394-H398 WeakPolarHBondContact O-CB 3.24Å; I394-H398 PolarHBondContact O-N 3.16Å; I394-H398 VanDerWaalsContact O-N 3.11Å; H398-N400 PolarHBondContact ND1-N 3.42Å; H398-N400 VanDerWaalsContact ND1-N 3.1Å; H398-N400 PolarHBondContact ND1-O 2.87Å; H398-N400 PolarHBondContact O-N 3.01Å; H398-V404 HydrophobicContact CB-CG2 3.89Å
399	W	94.3	Very high	93.5	Very high	174 Å²	174	57 Å²	57	66%	0.659	29%	0.291	S	S	*	.	S	Bend	trans	-71.2	-28.7	-175	68.7	-92.9	0	0	0	113.5	P355 F357 P401	P355-W399 PolarHBondContact O-NE1 3.24Å; P355-W399 VanDerWaalsContact O-NE1 3.14Å; F357-W399 HydrophobicContact CB-CZ2 4.19Å; F357-W399 HydrophobicContact CD1-CZ2 4.44Å; W399-P401 WeakPolarHBondContact O-CD 3.47Å
400	N	94	Very high	93.7	Very high	28 Å²	28	54.5 Å²	54.5	15%	0.15	27%	0.273	C	S	.	.			trans	-91.5	116.6	-179.5	-173.9	-25.1	0	0	0	111.1	H398 A402 I403 V404	H398-N400 PolarHBondContact ND1-N 3.42Å; H398-N400 VanDerWaalsContact ND1-N 3.1Å; H398-N400 PolarHBondContact ND1-O 2.87Å; H398-N400 PolarHBondContact O-N 3.01Å; N400-A402 VanDerWaalsContact C-N 3.31Å; N400-A402 PolarHBondContact O-N 3.28Å; N400-A402 WeakPolarHBondContact OD1-CB 3.38Å; N400-A402 PolarHBondContact OD1-N 3.23Å; N400-I403 HydrophobicContact CB-CB 4.43Å; N400-I403 HydrophobicContact CB-CG1 3.95Å; N400-I403 PolarHBondContact O-N 2.88Å; N400-V404 PolarHBondContact O-N 3.31Å
401	P	94.8	Very high	93.8	Very high	100 Å²	100	54.5 Å²	54.5	65%	0.649	27%	0.272	S	S	*	.	H	α-helix	trans	-62.1	-29.9	-179.9	-23.9	34.7	0	0	0	115.1	W399 V404 A405	W399-P401 WeakPolarHBondContact O-CD 3.47Å; P401-V404 WeakPolarHBondContact O-CB 3.44Å; P401-V404 PolarHBondContact O-N 3.36Å; P401-A405 PolarHBondContact O-N 3.07Å
402	A	95.1	Very high	93.7	Very high	58 Å²	58	60 Å²	60	48%	0.479	30%	0.296	S	S	.	.	H	α-helix	trans	-66.2	-41.1	178.8	0	0	0	0	0	111.3	N400 V404 A405 L406	N400-A402 VanDerWaalsContact C-N 3.31Å; N400-A402 PolarHBondContact O-N 3.28Å; N400-A402 WeakPolarHBondContact OD1-CB 3.38Å; N400-A402 PolarHBondContact OD1-N 3.23Å; A402-V404 VanDerWaalsContact C-N 3.34Å; A402-A405 PolarHBondContact O-N 3.06Å; A402-L406 WeakPolarHBondContact O-CG 3.13Å; A402-L406 PolarHBondContact O-N 3.27Å
403	I	95.5	Very high	93.9	Very high	2 Å²	2	59.2 Å²	59.2	1%	0.01	30%	0.298	C	S	.	.	H	α-helix	trans	-63.2	-43.3	174.1	-57.6	-57.4	0	0	0	110.4	F357 A360 E361 L364 I394 N400 A405 L406 V407	F357-I403 HydrophobicContact CB-CD1 4.44Å; F357-I403 HydrophobicContact CB-CG1 4.33Å; A360-I403 HydrophobicContact CB-CD1 4.25Å; A360-I403 HydrophobicContact CB-CG2 4.11Å; E361-I403 HydrophobicContact CB-CD1 3.69Å; L364-I403 HydrophobicContact CD1-CG2 3.9Å; I394-I403 HydrophobicContact CG2-CG2 4.18Å; N400-I403 HydrophobicContact CB-CB 4.43Å; N400-I403 HydrophobicContact CB-CG1 3.95Å; N400-I403 PolarHBondContact O-N 2.88Å; I403-A405 VanDerWaalsContact C-N 3.29Å; I403-A405 PolarHBondContact O-N 3.29Å; I403-L406 PolarHBondContact O-N 3.06Å; I403-V407 HydrophobicContact CG2-CG2 4.34Å; I403-V407 VanDerWaalsContact O-CG2 3.3Å; I403-V407 WeakPolarHBondContact O-CG2 3.42Å; I403-V407 PolarHBondContact O-N 3.07Å
404	V	95.4	Very high	94	Very high	27 Å²	27	54.6 Å²	54.6	16%	0.164	28%	0.28	C	S	.	.	H	α-helix	trans	-57.7	-44	176.3	174.1	0	0	0	0	110.9	H398 N400 P401 A402 V407 Y408	H398-V404 HydrophobicContact CB-CG2 3.89Å; N400-V404 PolarHBondContact O-N 3.31Å; P401-V404 WeakPolarHBondContact O-CB 3.44Å; P401-V404 PolarHBondContact O-N 3.36Å; A402-V404 VanDerWaalsContact C-N 3.34Å; V404-V407 PolarHBondContact O-N 3.16Å; V404-Y408 HydrophobicContact CG1-CD2 3.73Å; V404-Y408 HydrophobicContact CG1-CE2 3.4Å; V404-Y408 VanDerWaalsContact CG1-CE2 3.4Å; V404-Y408 WeakPolarHBondContact O-CD2 3.46Å; V404-Y408 PolarHBondContact O-N 3.37Å
405	A	95.6	Very high	94.1	Very high	51 Å²	51	58 Å²	58	42%	0.421	30%	0.297	S	S	.	.	H	α-helix	trans	-62.7	-44.6	176.6	0	0	0	0	0	112.8	P401 A402 I403 V407 Y408 N409	P401-A405 PolarHBondContact O-N 3.07Å; A402-A405 PolarHBondContact O-N 3.06Å; I403-A405 VanDerWaalsContact C-N 3.29Å; I403-A405 PolarHBondContact O-N 3.29Å; A405-V407 VanDerWaalsContact C-N 3.35Å; A405-V407 PolarHBondContact O-N 2.88Å; A405-Y408 PolarHBondContact O-N 2.93Å; A405-N409 PolarHBondContact O-N 3.07Å; A405-N409 VanDerWaalsContact O-N 3.11Å
406	L	96.2	Very high	94.1	Very high	34 Å²	34	63.9 Å²	63.9	18%	0.178	32%	0.323	C	S	.	.	H	α-helix	trans	-60.5	-43.8	174.9	-71.2	174.3	0	0	0	111.7	E361 L364 Y365 A402 I403 Y408 N409 V410	E361-L406 HydrophobicContact CG-CD1 4.06Å; L364-L406 HydrophobicContact CB-CB 4.24Å; L364-L406 HydrophobicContact CB-CD1 4.44Å; L364-L406 HydrophobicContact CD1-CB 3.81Å; L364-L406 HydrophobicContact CD1-CD1 4.43Å; Y365-L406 HydrophobicContact CE1-CD1 4.13Å; Y365-L406 HydrophobicContact CE1-CD2 4.03Å; A402-L406 WeakPolarHBondContact O-CG 3.13Å; A402-L406 PolarHBondContact O-N 3.27Å; I403-L406 PolarHBondContact O-N 3.06Å; L406-Y408 VanDerWaalsContact C-N 3.32Å; L406-Y408 PolarHBondContact O-N 2.91Å; L406-N409 WeakPolarHBondContact O-CB 3.44Å; L406-N409 PolarHBondContact O-N 3.21Å; L406-V410 WeakPolarHBondContact O-CG2 3.3Å; L406-V410 PolarHBondContact O-N 3.38Å
407	V	96.5	Very high	94.2	Very high	0 Å²	0	60.4 Å²	60.4	0%	0	31%	0.31	C	S	.	.	H	α-helix	trans	-61.6	-39.4	176.5	172.1	0	0	0	0	111.6	L364 L391 I394 I403 V404 A405 N409 V410 L411	L364-V407 HydrophobicContact CD1-CG2 3.67Å; L364-V407 HydrophobicContact CD2-CG2 3.86Å; L364-V407 HydrophobicContact CG-CG2 4.42Å; L391-V407 HydrophobicContact CB-CG1 4.17Å; L391-V407 HydrophobicContact CD2-CG1 3.99Å; L391-V407 HydrophobicContact CD2-CG2 4.44Å; L391-V407 VanDerWaalsContact O-CG1 3.22Å; L391-V407 WeakPolarHBondContact O-CG1 3.22Å; I394-V407 HydrophobicContact CB-CG2 4.42Å; I394-V407 HydrophobicContact CG2-CG2 3.78Å; I403-V407 HydrophobicContact CG2-CG2 4.34Å; I403-V407 VanDerWaalsContact O-CG2 3.3Å; I403-V407 WeakPolarHBondContact O-CG2 3.42Å; I403-V407 PolarHBondContact O-N 3.07Å; V404-V407 PolarHBondContact O-N 3.16Å; A405-V407 VanDerWaalsContact C-N 3.35Å; A405-V407 PolarHBondContact O-N 2.88Å; V407-N409 VanDerWaalsContact C-N 3.34Å; V407-N409 PolarHBondContact O-N 3.05Å; V407-V410 PolarHBondContact O-N 3.23Å; V407-L411 HydrophobicContact CG1-CD1 4.02Å; V407-L411 HydrophobicContact CG1-CG 4.31Å; V407-L411 WeakPolarHBondContact O-CB 3.49Å; V407-L411 WeakPolarHBondContact O-CG 3.21Å; V407-L411 PolarHBondContact O-N 2.88Å
408	Y	95.1	Very high	94.3	Very high	124 Å²	124	55.6 Å²	55.6	49%	0.486	29%	0.288	S	S	.	.	H	α-helix	trans	-62.3	-40.7	174.9	-83.5	-62.4	0	0	0	112.4	V404 A405 L406 V410 L411 K412	V404-Y408 HydrophobicContact CG1-CD2 3.73Å; V404-Y408 HydrophobicContact CG1-CE2 3.4Å; V404-Y408 VanDerWaalsContact CG1-CE2 3.4Å; V404-Y408 WeakPolarHBondContact O-CD2 3.46Å; V404-Y408 PolarHBondContact O-N 3.37Å; A405-Y408 PolarHBondContact O-N 2.93Å; L406-Y408 VanDerWaalsContact C-N 3.32Å; L406-Y408 PolarHBondContact O-N 2.91Å; Y408-V410 VanDerWaalsContact C-N 3.32Å; Y408-V410 PolarHBondContact O-N 2.99Å; Y408-L411 PolarHBondContact O-N 3.5Å; Y408-K412 WeakPolarHBondContact O-CB 3.29Å; Y408-K412 PolarHBondContact O-N 3.14Å
409	N	95.1	Very high	94.5	Very high	106 Å²	106	57.6 Å²	57.6	57%	0.567	30%	0.304	S	S	*	.	H	α-helix	trans	-60.6	-44.1	174.6	-67.2	-17.8	0	0	0	111.1	A405 L406 V407 K412 A413	A405-N409 PolarHBondContact O-N 3.07Å; A405-N409 VanDerWaalsContact O-N 3.11Å; L406-N409 WeakPolarHBondContact O-CB 3.44Å; L406-N409 PolarHBondContact O-N 3.21Å; V407-N409 VanDerWaalsContact C-N 3.34Å; V407-N409 PolarHBondContact O-N 3.05Å; N409-K412 WeakPolarHBondContact O-CB 3.37Å; N409-K412 PolarHBondContact O-N 2.95Å; N409-A413 PolarHBondContact O-N 3.45Å
410	V	96.3	Very high	94.4	Very high	5 Å²	5	53.6 Å²	53.6	3%	0.03	30%	0.299	C	S	.	.	H	α-helix	trans	-63.7	-45.5	176.9	172.1	0	0	0	0	112.1	L364 W367 L391 L406 V407 Y408 K412 A413 F414	L364-V410 HydrophobicContact CD2-CB 4.45Å; L364-V410 HydrophobicContact CD2-CG2 3.81Å; W367-V410 HydrophobicContact CB-CG2 3.82Å; W367-V410 HydrophobicContact CD2-CB 4.29Å; W367-V410 HydrophobicContact CD2-CG1 3.64Å; W367-V410 HydrophobicContact CD2-CG2 3.64Å; W367-V410 HydrophobicContact CE3-CG1 4.29Å; W367-V410 HydrophobicContact CE3-CG2 3.92Å; W367-V410 HydrophobicContact CG-CB 4.26Å; W367-V410 HydrophobicContact CG-CG1 3.89Å; W367-V410 HydrophobicContact CG-CG2 3.58Å; W367-V410 HydrophobicContact CZ2-CG1 3.86Å; L391-V410 HydrophobicContact CD1-CG1 3.69Å; L391-V410 HydrophobicContact CD2-CB 4.25Å; L391-V410 HydrophobicContact CD2-CG1 3.73Å; L391-V410 HydrophobicContact CG-CG1 4.39Å; L406-V410 WeakPolarHBondContact O-CG2 3.3Å; L406-V410 PolarHBondContact O-N 3.38Å; V407-V410 PolarHBondContact O-N 3.23Å; Y408-V410 VanDerWaalsContact C-N 3.32Å; Y408-V410 PolarHBondContact O-N 2.99Å; V410-K412 VanDerWaalsContact C-N 3.28Å; V410-K412 PolarHBondContact O-N 3.22Å; V410-A413 PolarHBondContact O-N 3.5Å; V410-F414 HydrophobicContact CG1-CD2 3.78Å; V410-F414 HydrophobicContact CG1-CE2 3.68Å; V410-F414 WeakPolarHBondContact O-CD2 3.38Å; V410-F414 PolarHBondContact O-N 2.76Å
411	L	95.2	Very high	94.3	Very high	14 Å²	14	54 Å²	54	7%	0.073	30%	0.301	C	S	.	.	H	α-helix	trans	-59.8	-40.1	175.8	-76.2	170.9	0	0	0	111.5	L391 V407 Y408 F414 M415 F422	L391-L411 HydrophobicContact CB-CD2 3.67Å; L391-L411 HydrophobicContact CB-CG 4.08Å; L391-L411 HydrophobicContact CD1-CD2 4.32Å; V407-L411 HydrophobicContact CG1-CD1 4.02Å; V407-L411 HydrophobicContact CG1-CG 4.31Å; V407-L411 WeakPolarHBondContact O-CB 3.49Å; V407-L411 WeakPolarHBondContact O-CG 3.21Å; V407-L411 PolarHBondContact O-N 2.88Å; Y408-L411 PolarHBondContact O-N 3.5Å; L411-F414 PolarHBondContact O-N 2.95Å; L411-M415 WeakPolarHBondContact O-CB 3.44Å; L411-M415 PolarHBondContact O-N 3.19Å; L411-F422 HydrophobicContact CB-CE2 4.46Å; L411-F422 HydrophobicContact CB-CZ 4.44Å; L411-F422 HydrophobicContact CD2-CE2 3.94Å; L411-F422 HydrophobicContact CD2-CZ 4.14Å; L411-F422 WeakPolarHBondContact O-CE2 3.31Å
412	K	94.3	Very high	94.3	Very high	115 Å²	115	50.3 Å²	50.3	50%	0.5	28%	0.275	S	S	.	.	H	α-helix	trans	-63.2	-45.3	175.9	-168.9	-172.7	-177.7	-119.9	0	111.5	Y408 N409 V410 F414 M415 E416	Y408-K412 WeakPolarHBondContact O-CB 3.29Å; Y408-K412 PolarHBondContact O-N 3.14Å; N409-K412 WeakPolarHBondContact O-CB 3.37Å; N409-K412 PolarHBondContact O-N 2.95Å; V410-K412 VanDerWaalsContact C-N 3.28Å; V410-K412 PolarHBondContact O-N 3.22Å; K412-F414 VanDerWaalsContact C-N 3.34Å; K412-F414 PolarHBondContact O-N 3.34Å; K412-M415 HydrophobicContact CG-CE 4.43Å; K412-M415 WeakPolarHBondContact O-CB 3.19Å; K412-M415 PolarHBondContact O-N 2.85Å; K412-E416 WeakPolarHBondContact CE-OE1 3.49Å; K412-E416 IonicContact NZ-OE1 3.09Å; K412-E416 PolarHBondContact NZ-OE1 3.4Å; K412-E416 WeakPolarHBondContact O-CG 3.39Å; K412-E416 PolarHBondContact O-N 2.97Å
413	A	94.5	Very high	94.2	Very high	25 Å²	25	52.4 Å²	52.4	21%	0.207	28%	0.278	C	S	.	.	H	α-helix	trans	-59.5	-44.1	176.6	0	0	0	0	0	111.7	M373 N409 V410 M415 E416 M417	M373-A413 HydrophobicContact CE-CB 4.18Å; N409-A413 PolarHBondContact O-N 3.45Å; V410-A413 PolarHBondContact O-N 3.5Å; A413-M415 VanDerWaalsContact C-N 3.33Å; A413-M415 PolarHBondContact O-N 2.76Å; A413-E416 PolarHBondContact O-N 2.83Å; A413-M417 VanDerWaalsContact O-CB 3.28Å; A413-M417 WeakPolarHBondContact O-CB 3.4Å; A413-M417 PolarHBondContact O-N 2.95Å
414	F	94.4	Very high	94.1	Very high	2 Å²	2	57.9 Å²	57.9	1%	0.009	30%	0.303	C	S	.	.	H	α-helix	trans	-62.3	-38.2	175	-85.8	-63.1	0	0	0	113.5	W367 I376 I383 L384 M387 L391 V410 L411 K412 M417 N418 F422	W367-F414 AromaticContact CE2-CE2 3.7Å; W367-F414 AromaticContact CZ2-CE2 3.66Å; W367-F414 HydrophobicContact CZ2-CE2 3.66Å; W367-F414 AromaticContact CZ2-CZ 3.89Å; W367-F414 HydrophobicContact CZ2-CZ 3.89Å; W367-F414 AromaticContact NE1-CE2 3.27Å; W367-F414 VanDerWaalsContact NE1-CE2 3.27Å; W367-F414 AromaticContact NE1-CZ 3.56Å; I376-F414 HydrophobicContact CG2-CE1 3.81Å; I376-F414 HydrophobicContact CG2-CZ 4.2Å; I383-F414 HydrophobicContact CG2-CE1 4.29Å; I383-F414 HydrophobicContact CG2-CZ 4.22Å; L384-F414 HydrophobicContact CB-CD1 4.01Å; L384-F414 HydrophobicContact CB-CE1 4.08Å; L384-F414 HydrophobicContact CD1-CB 3.82Å; L384-F414 HydrophobicContact CD1-CD1 3.51Å; L384-F414 HydrophobicContact CD1-CD2 4.37Å; L384-F414 HydrophobicContact CD1-CE1 4.13Å; L384-F414 HydrophobicContact CD1-CG 3.66Å; L384-F414 HydrophobicContact CG-CD1 4.21Å; M387-F414 HydrophobicContact CB-CE2 4.28Å; M387-F414 HydrophobicContact CB-CZ 4.19Å; M387-F414 HydrophobicContact CG-CZ 4.32Å; L391-F414 HydrophobicContact CD1-CD2 3.83Å; L391-F414 HydrophobicContact CD1-CE2 3.64Å; V410-F414 HydrophobicContact CG1-CD2 3.78Å; V410-F414 HydrophobicContact CG1-CE2 3.68Å; V410-F414 WeakPolarHBondContact O-CD2 3.38Å; V410-F414 PolarHBondContact O-N 2.76Å; L411-F414 PolarHBondContact O-N 2.95Å; K412-F414 VanDerWaalsContact C-N 3.34Å; K412-F414 PolarHBondContact O-N 3.34Å; F414-M417 HydrophobicContact CD1-CE 3.4Å; F414-M417 HydrophobicContact CE1-CE 3.62Å; F414-M417 PolarHBondContact O-N 3.5Å; F414-N418 PolarHBondContact O-N 3.28Å; F414-F422 HydrophobicContact CB-CD2 4.07Å; F414-F422 HydrophobicContact CB-CE2 4.25Å
415	M	93.4	Very high	94	Very high	84 Å²	84	58.3 Å²	58.3	41%	0.414	30%	0.304	S	S	.	.	H	α-helix	trans	-67.3	-40.6	176.6	-176.3	-173.3	71.3	0	0	111.9	L411 K412 A413 M417 S419 F422	L411-M415 WeakPolarHBondContact O-CB 3.44Å; L411-M415 PolarHBondContact O-N 3.19Å; K412-M415 HydrophobicContact CG-CE 4.43Å; K412-M415 WeakPolarHBondContact O-CB 3.19Å; K412-M415 PolarHBondContact O-N 2.85Å; A413-M415 VanDerWaalsContact C-N 3.33Å; A413-M415 PolarHBondContact O-N 2.76Å; M415-M417 VanDerWaalsContact C-N 3.3Å; M415-S419 WeakPolarHBondContact O-CA 3.23Å; M415-S419 WeakPolarHBondContact O-CB 3.35Å; M415-S419 PolarHBondContact O-N 3.02Å; M415-F422 HydrophobicContact CB-CD1 4.19Å; M415-F422 HydrophobicContact CB-CD2 4.14Å; M415-F422 HydrophobicContact CB-CE1 4.32Å; M415-F422 HydrophobicContact CB-CE2 4.26Å; M415-F422 HydrophobicContact CB-CG 4.09Å; M415-F422 HydrophobicContact CB-CZ 4.36Å; M415-F422 HydrophobicContact CG-CD1 4.16Å; M415-F422 HydrophobicContact CG-CE1 4.43Å; M415-F422 HydrophobicContact CG-CG 4.41Å
416	E	93	Very high	93.8	Very high	130 Å²	130	57.2 Å²	57.2	61%	0.607	29%	0.292	S	S	*	.	H	α-helix	trans	-66.2	-33.8	175.6	-71.4	173.8	-173.5	0	0	111.6	K412 A413	K412-E416 WeakPolarHBondContact CE-OE1 3.49Å; K412-E416 IonicContact NZ-OE1 3.09Å; K412-E416 PolarHBondContact NZ-OE1 3.4Å; K412-E416 WeakPolarHBondContact O-CG 3.39Å; K412-E416 PolarHBondContact O-N 2.97Å; A413-E416 PolarHBondContact O-N 2.83Å
417	M	91.2	Very high	93.6	Very high	36 Å²	36	58.4 Å²	58.4	18%	0.177	31%	0.307	C	S	.	.	H	α-helix	trans	-77.6	-42.3	-178.4	-172.1	173.8	81.4	0	0	114.1	I376 E377 A413 F414 M415	I376-M417 HydrophobicContact CG2-CE 3.61Å; I376-M417 HydrophobicContact CG2-SD 3.97Å; E377-M417 WeakPolarHBondContact CA-SD 3.46Å; E377-M417 HydrophobicContact CB-CG 4.08Å; E377-M417 HydrophobicContact CB-SD 3.73Å; E377-M417 HydrophobicContact CG-CG 3.88Å; E377-M417 HydrophobicContact CG-SD 4.22Å; A413-M417 VanDerWaalsContact O-CB 3.28Å; A413-M417 WeakPolarHBondContact O-CB 3.4Å; A413-M417 PolarHBondContact O-N 2.95Å; F414-M417 HydrophobicContact CD1-CE 3.4Å; F414-M417 HydrophobicContact CE1-CE 3.62Å; F414-M417 PolarHBondContact O-N 3.5Å; M415-M417 VanDerWaalsContact C-N 3.3Å
418	N	91	Very high	93.4	Very high	30 Å²	30	61.1 Å²	61.1	16%	0.16	32%	0.324	C	S	.	.			trans	-150.4	77.5	-179.3	-168.7	-22.8	0	0	0	111	S380 N381 L384 F414 T420 M421 F422	S380-N418 PolarHBondContact OG-ND2 3.44Å; N381-N418 PolarHBondContact OD1-ND2 3.47Å; L384-N418 HydrophobicContact CD2-CB 4.34Å; F414-N418 PolarHBondContact O-N 3.28Å; N418-T420 VanDerWaalsContact C-N 3.34Å; N418-T420 PolarHBondContact O-N 3.44Å; N418-M421 HydrophobicContact CB-CB 4.48Å; N418-M421 PolarHBondContact O-N 3.38Å; N418-M421 VanDerWaalsContact OD1-CB 3.31Å; N418-M421 WeakPolarHBondContact OD1-CB 3.24Å; N418-M421 PolarHBondContact OD1-N 3.35Å; N418-M421 VanDerWaalsContact OD1-N 3.13Å; N418-F422 WeakPolarHBondContact O-CB 3.33Å; N418-F422 PolarHBondContact O-N 3.13Å
419	S	93.2	Very high	93.1	Very high	64 Å²	64	57.8 Å²	57.8	45%	0.448	31%	0.311	S	S	.	.	H	α-helix	trans	-59.2	-41.8	-175.8	62.7	0	0	0	0	112.9	M415 F422 D423	M415-S419 WeakPolarHBondContact O-CA 3.23Å; M415-S419 WeakPolarHBondContact O-CB 3.35Å; M415-S419 PolarHBondContact O-N 3.02Å; S419-F422 WeakPolarHBondContact O-CB 3.12Å; S419-F422 PolarHBondContact O-N 3.13Å; S419-D423 PolarHBondContact O-N 3.47Å
420	T	93.3	Very high	92.8	Very high	90 Å²	90	55.3 Å²	55.3	55%	0.552	30%	0.298	S	S	*	.	H	α-helix	trans	-61.8	-50.9	-177.8	-51.6	0	0	0	0	111.5	N418 F422 D423 E424	N418-T420 VanDerWaalsContact C-N 3.34Å; N418-T420 PolarHBondContact O-N 3.44Å; T420-F422 VanDerWaalsContact C-N 3.3Å; T420-F422 PolarHBondContact O-N 2.99Å; T420-D423 PolarHBondContact O-N 3.26Å; T420-E424 WeakPolarHBondContact O-CG 3.5Å; T420-E424 PolarHBondContact O-N 3.26Å; T420-E424 VanDerWaalsContact O-N 3.08Å
421	M	92.2	Very high	92.5	Very high	37 Å²	37	61.5 Å²	61.5	18%	0.182	33%	0.326	C	S	.	.	H	α-helix	trans	-66.8	-35.4	178.4	-178.1	173.7	-111.5	0	0	111.6	N381 L384 P385 N418 D423 E424 L425	N381-M421 WeakPolarHBondContact O-CE 3.47Å; L384-M421 HydrophobicContact CB-SD 4.23Å; L384-M421 HydrophobicContact CD2-CB 3.96Å; L384-M421 HydrophobicContact CD2-CG 3.78Å; L384-M421 HydrophobicContact CD2-SD 4.02Å; L384-M421 HydrophobicContact CG-CG 4.39Å; L384-M421 HydrophobicContact CG-SD 4.34Å; P385-M421 HydrophobicContact CG-CE 3.65Å; P385-M421 HydrophobicContact CG-SD 3.78Å; N418-M421 HydrophobicContact CB-CB 4.48Å; N418-M421 PolarHBondContact O-N 3.38Å; N418-M421 VanDerWaalsContact OD1-CB 3.31Å; N418-M421 WeakPolarHBondContact OD1-CB 3.24Å; N418-M421 PolarHBondContact OD1-N 3.35Å; N418-M421 VanDerWaalsContact OD1-N 3.13Å; M421-D423 VanDerWaalsContact C-N 3.35Å; M421-D423 PolarHBondContact O-N 3.5Å; M421-E424 PolarHBondContact O-N 3.16Å; M421-L425 HydrophobicContact CG-CD1 3.83Å; M421-L425 HydrophobicContact CG-CG 4.23Å; M421-L425 WeakPolarHBondContact O-CB 2.88Å; M421-L425 VanDerWaalsContact O-CG 3.24Å; M421-L425 WeakPolarHBondContact O-CG 3.39Å; M421-L425 PolarHBondContact O-N 3.43Å
422	F	93.3	Very high	92.2	Very high	23 Å²	23	66.9 Å²	66.9	10%	0.101	35%	0.349	C	S	.	.	H	α-helix	trans	-60.8	-44.3	176.4	-170.5	-84.4	0	0	0	111.8	L384 F388 L411 F414 M415 N418 S419 T420 L425 T426	L384-F422 HydrophobicContact CD1-CD2 4.28Å; L384-F422 HydrophobicContact CD2-CB 4.39Å; F388-F422 HydrophobicContact CD2-CD2 4.22Å; F388-F422 HydrophobicContact CD2-CE2 4.14Å; F388-F422 HydrophobicContact CE2-CD1 4.49Å; F388-F422 HydrophobicContact CE2-CD2 4.03Å; F388-F422 HydrophobicContact CE2-CE1 4.28Å; F388-F422 AromaticContact CE2-CE2 3.81Å; F388-F422 HydrophobicContact CE2-CE2 3.81Å; F388-F422 HydrophobicContact CE2-CG 4.37Å; F388-F422 AromaticContact CE2-CZ 3.94Å; F388-F422 HydrophobicContact CE2-CZ 3.94Å; L411-F422 HydrophobicContact CB-CE2 4.46Å; L411-F422 HydrophobicContact CB-CZ 4.44Å; L411-F422 HydrophobicContact CD2-CE2 3.94Å; L411-F422 HydrophobicContact CD2-CZ 4.14Å; L411-F422 WeakPolarHBondContact O-CE2 3.31Å; F414-F422 HydrophobicContact CB-CD2 4.07Å; F414-F422 HydrophobicContact CB-CE2 4.25Å; M415-F422 HydrophobicContact CB-CD1 4.19Å; M415-F422 HydrophobicContact CB-CD2 4.14Å; M415-F422 HydrophobicContact CB-CE1 4.32Å; M415-F422 HydrophobicContact CB-CE2 4.26Å; M415-F422 HydrophobicContact CB-CG 4.09Å; M415-F422 HydrophobicContact CB-CZ 4.36Å; M415-F422 HydrophobicContact CG-CD1 4.16Å; M415-F422 HydrophobicContact CG-CE1 4.43Å; M415-F422 HydrophobicContact CG-CG 4.41Å; N418-F422 WeakPolarHBondContact O-CB 3.33Å; N418-F422 PolarHBondContact O-N 3.13Å; S419-F422 WeakPolarHBondContact O-CB 3.12Å; S419-F422 PolarHBondContact O-N 3.13Å; T420-F422 VanDerWaalsContact C-N 3.3Å; T420-F422 PolarHBondContact O-N 2.99Å; F422-L425 PolarHBondContact O-N 3.13Å; F422-T426 WeakPolarHBondContact O-CB 3.48Å; F422-T426 PolarHBondContact O-N 3.31Å; F422-T426 PolarHBondContact O-OG1 3.46Å
423	D	93.2	Very high	91.7	Very high	102 Å²	102	65.3 Å²	65.3	55%	0.545	34%	0.342	S	S	.	.	H	α-helix	trans	-66	-44.1	177.7	-72.3	-23.4	0	0	0	111.8	S419 T420 M421 L425 T426 A427	S419-D423 PolarHBondContact O-N 3.47Å; T420-D423 PolarHBondContact O-N 3.26Å; M421-D423 VanDerWaalsContact C-N 3.35Å; M421-D423 PolarHBondContact O-N 3.5Å; D423-L425 PolarHBondContact O-N 3.09Å; D423-T426 WeakPolarHBondContact O-CB 3.23Å; D423-T426 PolarHBondContact O-N 2.97Å; D423-A427 PolarHBondContact O-N 2.85Å
424	E	93.7	Very high	91.4	Very high	117 Å²	117	71.3 Å²	71.3	55%	0.547	36%	0.364	S	S	.	.	H	α-helix	trans	-59.4	-44.9	176	-73.7	176.8	-175.7	0	0	112.3	T420 M421 A427 T428	T420-E424 WeakPolarHBondContact O-CG 3.5Å; T420-E424 PolarHBondContact O-N 3.26Å; T420-E424 VanDerWaalsContact O-N 3.08Å; M421-E424 PolarHBondContact O-N 3.16Å; E424-A427 PolarHBondContact O-N 2.92Å; E424-T428 WeakPolarHBondContact O-CB 3.19Å; E424-T428 PolarHBondContact O-N 2.92Å; E424-T428 PolarHBondContact O-OG1 3.07Å
425	L	93.6	Very high	91.1	Very high	35 Å²	35	75.2 Å²	75.2	18%	0.183	38%	0.382	C	S	.	.	H	α-helix	trans	-67.6	-36.9	177.4	-71.1	170.5	0	0	0	111.8	L384 P385 F388 M421 F422 D423 T428 Y429	L384-L425 HydrophobicContact CD1-CD1 4.3Å; L384-L425 HydrophobicContact CD2-CD1 4.18Å; L384-L425 HydrophobicContact CG-CD1 3.65Å; P385-L425 HydrophobicContact CB-CD1 4.37Å; P385-L425 HydrophobicContact CB-CD2 4.21Å; P385-L425 HydrophobicContact CG-CD1 4.18Å; P385-L425 HydrophobicContact CG-CD2 4.49Å; F388-L425 HydrophobicContact CB-CD1 4Å; F388-L425 HydrophobicContact CD1-CB 3.84Å; F388-L425 HydrophobicContact CD2-CB 4.02Å; F388-L425 HydrophobicContact CD2-CD1 4.32Å; F388-L425 HydrophobicContact CE1-CB 4.06Å; F388-L425 WeakPolarHBondContact CE1-O 3.47Å; F388-L425 HydrophobicContact CE2-CB 4.21Å; F388-L425 HydrophobicContact CG-CB 3.85Å; F388-L425 HydrophobicContact CG-CD1 4.13Å; F388-L425 HydrophobicContact CZ-CB 4.25Å; M421-L425 HydrophobicContact CG-CD1 3.83Å; M421-L425 HydrophobicContact CG-CG 4.23Å; M421-L425 WeakPolarHBondContact O-CB 2.88Å; M421-L425 VanDerWaalsContact O-CG 3.24Å; M421-L425 WeakPolarHBondContact O-CG 3.39Å; M421-L425 PolarHBondContact O-N 3.43Å; F422-L425 PolarHBondContact O-N 3.13Å; D423-L425 PolarHBondContact O-N 3.09Å; L425-T428 PolarHBondContact O-N 3.43Å; L425-Y429 VanDerWaalsContact O-CB 3.23Å; L425-Y429 WeakPolarHBondContact O-CB 3.39Å; L425-Y429 PolarHBondContact O-N 3.24Å
426	T	91.5	Very high	90.8	Very high	28 Å²	28	77.7 Å²	77.7	17%	0.172	39%	0.391	C	S	.	.	H	α-helix	trans	-63	-46.1	175	-59.6	0	0	0	0	111.3	F388 F422 D423 Y429 N430	F388-T426 WeakPolarHBondContact CZ-OG1 3.24Å; F422-T426 WeakPolarHBondContact O-CB 3.48Å; F422-T426 PolarHBondContact O-N 3.31Å; F422-T426 PolarHBondContact O-OG1 3.46Å; D423-T426 WeakPolarHBondContact O-CB 3.23Å; D423-T426 PolarHBondContact O-N 2.97Å; T426-Y429 PolarHBondContact O-N 3.38Å; T426-N430 WeakPolarHBondContact O-CB 3.39Å; T426-N430 PolarHBondContact O-N 2.95Å; T426-N430 VanDerWaalsContact O-N 3.07Å; T426-N430 PolarHBondContact O-ND2 3.08Å; T426-N430 VanDerWaalsContact O-ND2 3.09Å
427	A	92.6	Very high	90.5	Very high	60 Å²	60	75.9 Å²	75.9	50%	0.496	38%	0.382	S	S	.	.	H	α-helix	trans	-60.4	-50.5	176.1	0	0	0	0	0	111.1	D423 E424 Y429 N430 E431	D423-A427 PolarHBondContact O-N 2.85Å; E424-A427 PolarHBondContact O-N 2.92Å; A427-Y429 VanDerWaalsContact C-N 3.34Å; A427-Y429 PolarHBondContact O-N 3.47Å; A427-N430 PolarHBondContact O-N 2.8Å; A427-E431 PolarHBondContact O-N 2.97Å
428	T	91.8	Very high	90.4	Very high	57 Å²	57	80.5 Å²	80.5	35%	0.35	40%	0.398	S	S	.	.	H	α-helix	trans	-60.3	-41.2	179.6	-56.3	0	0	0	0	112.2	E424 L425 K432	E424-T428 WeakPolarHBondContact O-CB 3.19Å; E424-T428 PolarHBondContact O-N 2.92Å; E424-T428 PolarHBondContact O-OG1 3.07Å; L425-T428 PolarHBondContact O-N 3.43Å; T428-K432 HydrophobicContact CG2-CD 4.25Å; T428-K432 WeakPolarHBondContact O-CB 3.39Å; T428-K432 WeakPolarHBondContact O-CG 3.43Å; T428-K432 PolarHBondContact O-N 3.38Å
429	Y	88.5	Confident	90.4	Very high	54 Å²	54	83.9 Å²	83.9	21%	0.212	41%	0.412	C	S	.	.	H	α-helix	trans	-65.8	-44.5	178.8	-174.7	-81.2	0	0	0	111.6	F388 Y392 L425 T426 A427 E431 K432 K433	F388-Y429 HydrophobicContact CE1-CD2 4.35Å; F388-Y429 HydrophobicContact CE1-CG 4.2Å; Y392-Y429 AromaticContact CD1-CD1 3.55Å; Y392-Y429 HydrophobicContact CD1-CD1 3.55Å; Y392-Y429 AromaticContact CD1-CE1 3.36Å; Y392-Y429 HydrophobicContact CD1-CE1 3.36Å; Y392-Y429 HydrophobicContact CD1-CE2 4.49Å; Y392-Y429 HydrophobicContact CD1-CG 4.23Å; Y392-Y429 AromaticContact CD1-CZ 3.86Å; Y392-Y429 AromaticContact CE1-CD1 3.71Å; Y392-Y429 HydrophobicContact CE1-CD1 3.71Å; Y392-Y429 AromaticContact CE1-CE1 3.71Å; Y392-Y429 HydrophobicContact CE1-CE1 3.71Å; Y392-Y429 HydrophobicContact CG-CE1 4.5Å; L425-Y429 VanDerWaalsContact O-CB 3.23Å; L425-Y429 WeakPolarHBondContact O-CB 3.39Å; L425-Y429 PolarHBondContact O-N 3.24Å; T426-Y429 PolarHBondContact O-N 3.38Å; A427-Y429 VanDerWaalsContact C-N 3.34Å; A427-Y429 PolarHBondContact O-N 3.47Å; Y429-E431 VanDerWaalsContact C-N 3.35Å; Y429-K432 PolarHBondContact O-N 3.47Å; Y429-K433 WeakPolarHBondContact O-CB 3.3Å; Y429-K433 PolarHBondContact O-N 3.24Å
430	N	88.2	Confident	90.3	Very high	54 Å²	54	86 Å²	86	29%	0.289	42%	0.415	S	S	.	.	H	α-helix	trans	-66.3	-37.1	178.6	-73.8	-36.4	0	0	0	112.1	T426 A427 K433 K434	T426-N430 WeakPolarHBondContact O-CB 3.39Å; T426-N430 PolarHBondContact O-N 2.95Å; T426-N430 VanDerWaalsContact O-N 3.07Å; T426-N430 PolarHBondContact O-ND2 3.08Å; T426-N430 VanDerWaalsContact O-ND2 3.09Å; A427-N430 PolarHBondContact O-N 2.8Å; N430-K433 PolarHBondContact O-N 2.95Å; N430-K434 WeakPolarHBondContact O-CG 3.41Å; N430-K434 PolarHBondContact O-N 3.21Å
431	E	90.2	Very high	90.1	Very high	135 Å²	135	87.3 Å²	87.3	63%	0.631	42%	0.418	S	S	*	.	H	α-helix	trans	-63.2	-50.8	173.7	-172.7	176.9	-167.3	0	0	111.5	A427 Y429 K433 K434 E435	A427-E431 PolarHBondContact O-N 2.97Å; Y429-E431 VanDerWaalsContact C-N 3.35Å; E431-K433 VanDerWaalsContact C-N 3.26Å; E431-K433 PolarHBondContact O-N 2.92Å; E431-K434 PolarHBondContact O-N 3.25Å; E431-K434 VanDerWaalsContact O-N 3.16Å; E431-E435 PolarHBondContact O-N 3Å
432	K	88.4	Confident	90	Very high	127 Å²	127	92.8 Å²	92.8	55%	0.552	44%	0.437	S	S	*	.	H	α-helix	trans	-59.3	-35.8	175.9	-74.5	178.5	179.6	176.5	0	112.8	T428 Y429 K436	T428-K432 HydrophobicContact CG2-CD 4.25Å; T428-K432 WeakPolarHBondContact O-CB 3.39Å; T428-K432 WeakPolarHBondContact O-CG 3.43Å; T428-K432 PolarHBondContact O-N 3.38Å; Y429-K432 PolarHBondContact O-N 3.47Å; K432-K436 WeakPolarHBondContact O-CG 3.24Å; K432-K436 PolarHBondContact O-N 2.91Å
433	K	84.8	Confident	89.9	Confident	82 Å²	82	98 Å²	98	36%	0.357	46%	0.459	S	S	.	.	H	α-helix	trans	-65.8	-48	175.6	-179.2	172.9	172	168.7	0	111.3	Y429 N430 E431 E435 K436 E437	Y429-K433 WeakPolarHBondContact O-CB 3.3Å; Y429-K433 PolarHBondContact O-N 3.24Å; N430-K433 PolarHBondContact O-N 2.95Å; E431-K433 VanDerWaalsContact C-N 3.26Å; E431-K433 PolarHBondContact O-N 2.92Å; K433-E435 VanDerWaalsContact C-N 3.27Å; K433-E435 PolarHBondContact O-N 3.38Å; K433-K436 PolarHBondContact O-N 3.16Å; K433-E437 WeakPolarHBondContact CE-OE1 3.37Å; K433-E437 IonicContact NZ-OE1 2.81Å; K433-E437 WeakPolarHBondContact O-CG 3.42Å; K433-E437 PolarHBondContact O-N 3.28Å
434	K	87.5	Confident	89.7	Confident	151 Å²	151	99.1 Å²	99.1	66%	0.657	46%	0.459	S	S	*	.	H	α-helix	trans	-60.4	-38.2	175.8	-72.9	175.5	-179.3	-179.7	0	111.9	N430 E431 R438	N430-K434 WeakPolarHBondContact O-CG 3.41Å; N430-K434 PolarHBondContact O-N 3.21Å; E431-K434 PolarHBondContact O-N 3.25Å; E431-K434 VanDerWaalsContact O-N 3.16Å; K434-R438 VanDerWaalsContact O-CB 3.29Å; K434-R438 WeakPolarHBondContact O-CB 3.42Å; K434-R438 PolarHBondContact O-N 3.45Å
435	E	87.8	Confident	89.5	Confident	84 Å²	84	98.1 Å²	98.1	39%	0.393	46%	0.458	S	S	.	.	H	α-helix	trans	-64.4	-46	175.8	178.9	158.7	-123.5	0	0	112.1	E431 K433 R438 E439	E431-E435 PolarHBondContact O-N 3Å; K433-E435 VanDerWaalsContact C-N 3.27Å; K433-E435 PolarHBondContact O-N 3.38Å; E435-R438 WeakPolarHBondContact O-CB 3.36Å; E435-R438 PolarHBondContact O-N 2.92Å; E435-R438 IonicContact OE1-NH2 3.56Å; E435-R438 PolarHBondContact OE1-NH2 2.96Å; E435-E439 WeakPolarHBondContact O-CG 3.36Å; E435-E439 PolarHBondContact O-N 3.06Å
436	K	87.1	Confident	89.3	Confident	136 Å²	136	102 Å²	102	59%	0.591	48%	0.475	S	S	*	.	H	α-helix	trans	-61.9	-44.4	174.3	-76	-177.4	177.3	-173.7	0	112.8	K432 K433 R438 E439 E440	K432-K436 WeakPolarHBondContact O-CG 3.24Å; K432-K436 PolarHBondContact O-N 2.91Å; K433-K436 PolarHBondContact O-N 3.16Å; K436-R438 VanDerWaalsContact C-N 3.26Å; K436-R438 PolarHBondContact O-N 3.01Å; K436-E439 PolarHBondContact O-N 3.03Å; K436-E440 WeakPolarHBondContact O-CG 3.25Å; K436-E440 PolarHBondContact O-N 3.42Å
437	E	87.5	Confident	89.2	Confident	92 Å²	92	105.2 Å²	105.2	43%	0.43	49%	0.491	S	S	.	.	H	α-helix	trans	-60	-39.7	176.1	-73.4	171.8	176.9	0	0	111.1	K433 L441	K433-E437 WeakPolarHBondContact CE-OE1 3.37Å; K433-E437 IonicContact NZ-OE1 2.81Å; K433-E437 WeakPolarHBondContact O-CG 3.42Å; K433-E437 PolarHBondContact O-N 3.28Å; E437-L441 WeakPolarHBondContact O-CB 3.22Å; E437-L441 WeakPolarHBondContact O-CD1 3.45Å; E437-L441 VanDerWaalsContact O-CG 3.24Å; E437-L441 WeakPolarHBondContact O-CG 3.47Å; E437-L441 PolarHBondContact O-N 3.4Å
438	R	90.1	Very high	88.9	Confident	133 Å²	133	107.8 Å²	107.8	50%	0.502	50%	0.496	S	S	.	.	H	α-helix	trans	-64.3	-45.5	173.8	-179.8	-178.9	64.3	-173.5	-1.9	111.8	K434 E435 K436 L441 W442	K434-R438 VanDerWaalsContact O-CB 3.29Å; K434-R438 WeakPolarHBondContact O-CB 3.42Å; K434-R438 PolarHBondContact O-N 3.45Å; E435-R438 WeakPolarHBondContact O-CB 3.36Å; E435-R438 PolarHBondContact O-N 2.92Å; E435-R438 IonicContact OE1-NH2 3.56Å; E435-R438 PolarHBondContact OE1-NH2 2.96Å; K436-R438 VanDerWaalsContact C-N 3.26Å; K436-R438 PolarHBondContact O-N 3.01Å; R438-L441 WeakPolarHBondContact O-CB 3.44Å; R438-L441 PolarHBondContact O-N 2.98Å; R438-W442 PolarHBondContact O-N 3.37Å
439	E	90.4	Very high	88.6	Confident	100 Å²	100	111.7 Å²	111.7	47%	0.467	51%	0.51	S	S	.	.	H	α-helix	trans	-62.2	-41.9	176	-74	-179.7	179.1	0	0	112.5	E435 K436 L441 W442 K443	E435-E439 WeakPolarHBondContact O-CG 3.36Å; E435-E439 PolarHBondContact O-N 3.06Å; K436-E439 PolarHBondContact O-N 3.03Å; E439-L441 VanDerWaalsContact C-N 3.35Å; E439-W442 PolarHBondContact O-N 2.92Å; E439-K443 WeakPolarHBondContact O-CG 3.47Å; E439-K443 PolarHBondContact O-N 3.35Å
440	E	90.3	Very high	88.1	Confident	110 Å²	110	114.8 Å²	114.8	51%	0.514	53%	0.53	S	S	.	.	H	α-helix	trans	-65.5	-38.4	175.7	-74	179.9	-172	0	0	112.2	K436 K444	K436-E440 WeakPolarHBondContact O-CG 3.25Å; K436-E440 PolarHBondContact O-N 3.42Å; E440-K444 WeakPolarHBondContact O-CB 3.49Å; E440-K444 VanDerWaalsContact O-CG 3.3Å; E440-K444 WeakPolarHBondContact O-CG 3.39Å; E440-K444 PolarHBondContact O-N 2.94Å
441	L	90.2	Very high	87.6	Confident	117 Å²	117	118.5 Å²	118.5	61%	0.613	54%	0.543	S	S	*	.	H	α-helix	trans	-62.7	-43.6	172.6	-78.7	162.9	0	0	0	111.3	E437 R438 E439 K444 L445	E437-L441 WeakPolarHBondContact O-CB 3.22Å; E437-L441 WeakPolarHBondContact O-CD1 3.45Å; E437-L441 VanDerWaalsContact O-CG 3.24Å; E437-L441 WeakPolarHBondContact O-CG 3.47Å; E437-L441 PolarHBondContact O-N 3.4Å; R438-L441 WeakPolarHBondContact O-CB 3.44Å; R438-L441 PolarHBondContact O-N 2.98Å; E439-L441 VanDerWaalsContact C-N 3.35Å; L441-K444 PolarHBondContact O-N 3.33Å; L441-L445 PolarHBondContact O-N 2.88Å
442	W	89.6	Confident	87	Confident	151 Å²	151	119.6 Å²	119.6	57%	0.572	54%	0.541	S	S	*	.	H	α-helix	trans	-63	-46	176	-78.3	118.2	0	0	0	112.3	R438 E439 K444 L445 E446	R438-W442 PolarHBondContact O-N 3.37Å; E439-W442 PolarHBondContact O-N 2.92Å; W442-K444 VanDerWaalsContact C-N 3.34Å; W442-K444 PolarHBondContact O-N 2.96Å; W442-L445 HydrophobicContact CE3-CD2 3.93Å; W442-L445 HydrophobicContact CZ3-CD2 3.73Å; W442-L445 WeakPolarHBondContact O-CA 3.5Å; W442-L445 WeakPolarHBondContact O-CB 3.29Å; W442-L445 PolarHBondContact O-N 2.88Å; W442-E446 WeakPolarHBondContact O-CG 3.4Å; W442-E446 PolarHBondContact O-N 3.13Å
443	K	90.9	Very high	86.2	Confident	133 Å²	133	115 Å²	115	58%	0.578	53%	0.529	S	S	*	.	H	α-helix	trans	-59.2	-42.6	174.6	-76.2	179.4	178.5	173.2	0	112.5	E439 L445 E446 D447	E439-K443 WeakPolarHBondContact O-CG 3.47Å; E439-K443 PolarHBondContact O-N 3.35Å; K443-L445 VanDerWaalsContact C-N 3.28Å; K443-L445 PolarHBondContact O-N 3Å; K443-E446 PolarHBondContact O-N 2.91Å; K443-D447 WeakPolarHBondContact O-CB 3.47Å; K443-D447 PolarHBondContact O-N 3.3Å
444	K	89.5	Confident	85.1	Confident	125 Å²	125	116.6 Å²	116.6	54%	0.543	54%	0.541	S	S	.	.	H	α-helix	trans	-62.7	-36.3	174.8	-75.8	171.4	-177.3	167.8	0	111.9	E440 L441 W442 L448	E440-K444 WeakPolarHBondContact O-CB 3.49Å; E440-K444 VanDerWaalsContact O-CG 3.3Å; E440-K444 WeakPolarHBondContact O-CG 3.39Å; E440-K444 PolarHBondContact O-N 2.94Å; L441-K444 PolarHBondContact O-N 3.33Å; W442-K444 VanDerWaalsContact C-N 3.34Å; W442-K444 PolarHBondContact O-N 2.96Å; K444-L448 WeakPolarHBondContact O-CB 3.16Å; K444-L448 WeakPolarHBondContact O-CG 3.35Å; K444-L448 PolarHBondContact O-N 2.93Å; K444-L448 VanDerWaalsContact O-N 3.1Å
445	L	90	Very high	83.8	Confident	97 Å²	97	120 Å²	120	51%	0.508	55%	0.55	S	S	.	.	H	α-helix	trans	-66.8	-46.1	176.6	-157.3	86.8	0	0	0	111.1	L441 W442 K443 L448 E449	L441-L445 PolarHBondContact O-N 2.88Å; W442-L445 HydrophobicContact CE3-CD2 3.93Å; W442-L445 HydrophobicContact CZ3-CD2 3.73Å; W442-L445 WeakPolarHBondContact O-CA 3.5Å; W442-L445 WeakPolarHBondContact O-CB 3.29Å; W442-L445 PolarHBondContact O-N 2.88Å; K443-L445 VanDerWaalsContact C-N 3.28Å; K443-L445 PolarHBondContact O-N 3Å; L445-L448 PolarHBondContact O-N 3.4Å; L445-E449 PolarHBondContact O-N 3.5Å
446	E	88.7	Confident	82.5	Confident	117 Å²	117	124.5 Å²	124.5	55%	0.547	56%	0.563	S	S	.	*	H	α-helix	trans	-61.1	-44.8	176	-72	174	-178	0	0	111.7	W442 K443 L448 E449 L450	W442-E446 WeakPolarHBondContact O-CG 3.4Å; W442-E446 PolarHBondContact O-N 3.13Å; K443-E446 PolarHBondContact O-N 2.91Å; E446-L448 VanDerWaalsContact C-N 3.31Å; E446-L448 PolarHBondContact O-N 2.98Å; E446-E449 PolarHBondContact O-N 2.87Å; E446-L450 WeakPolarHBondContact O-CB 3.5Å; E446-L450 PolarHBondContact O-N 3.23Å
447	D	88.4	Confident	81.1	Confident	94 Å²	94	124 Å²	124	50%	0.503	57%	0.567	S	S	.	*	H	α-helix	trans	-61.4	-38.3	175.8	-80	-15.6	0	0	0	112.3	K443 K451	K443-D447 WeakPolarHBondContact O-CB 3.47Å; K443-D447 PolarHBondContact O-N 3.3Å; D447-K451 WeakPolarHBondContact O-CB 3.49Å; D447-K451 VanDerWaalsContact O-CG 3.25Å; D447-K451 WeakPolarHBondContact O-CG 3.31Å; D447-K451 PolarHBondContact O-N 3.25Å
448	L	87.5	Confident	79.3	Confident	115 Å²	115	122.2 Å²	122.2	60%	0.602	57%	0.574	S	S	*	*	H	α-helix	trans	-69.7	-37.8	175.7	-75.1	171.4	0	0	0	111.6	K444 L445 E446 R452	K444-L448 WeakPolarHBondContact O-CB 3.16Å; K444-L448 WeakPolarHBondContact O-CG 3.35Å; K444-L448 PolarHBondContact O-N 2.93Å; K444-L448 VanDerWaalsContact O-N 3.1Å; L445-L448 PolarHBondContact O-N 3.4Å; E446-L448 VanDerWaalsContact C-N 3.31Å; E446-L448 PolarHBondContact O-N 2.98Å; L448-R452 VanDerWaalsContact O-CB 3.31Å; L448-R452 WeakPolarHBondContact O-CB 3.37Å; L448-R452 PolarHBondContact O-N 3.39Å
449	E	84.5	Confident	77.3	Confident	139 Å²	139	122.6 Å²	122.6	65%	0.65	58%	0.584	S	S	*	*	H	α-helix	trans	-66.3	-43.5	174.9	-171.2	165.6	-162.7	0	0	111.4	L445 E446 K451 R452 G453	L445-E449 PolarHBondContact O-N 3.5Å; E446-E449 PolarHBondContact O-N 2.87Å; E449-K451 PolarHBondContact O-N 3.1Å; E449-R452 CarbonylContact O-C 3.56Å; E449-R452 WeakPolarHBondContact O-CB 3.36Å; E449-R452 PolarHBondContact O-N 2.83Å; E449-R452 VanDerWaalsContact O-N 3.13Å; E449-G453 PolarHBondContact O-N 2.92Å
450	L	78.9	Confident	75.1	Confident	119 Å²	119	125.3 Å²	125.3	62%	0.623	60%	0.6	S	S	*	*	H	α-helix	trans	-62.1	-44.5	175.1	-149.3	97.1	0	0	0	111.6	E446 R452 G453 L454	E446-L450 WeakPolarHBondContact O-CB 3.5Å; E446-L450 PolarHBondContact O-N 3.23Å; L450-R452 VanDerWaalsContact C-N 3.28Å; L450-R452 PolarHBondContact O-N 2.92Å; L450-G453 PolarHBondContact O-N 2.9Å; L450-L454 HydrophobicContact CD2-CD1 4.39Å; L450-L454 WeakPolarHBondContact O-CB 3.5Å; L450-L454 WeakPolarHBondContact O-CG 3.46Å; L450-L454 PolarHBondContact O-N 3.18Å
451	K	78	Confident	72.9	Confident	131 Å²	131	124.8 Å²	124.8	57%	0.57	61%	0.606	S	S	*	*	H	α-helix	trans	-62.8	-34.4	174	-77.2	172.3	-177.6	170.9	0	112.2	D447 E449 R455	D447-K451 WeakPolarHBondContact O-CB 3.49Å; D447-K451 VanDerWaalsContact O-CG 3.25Å; D447-K451 WeakPolarHBondContact O-CG 3.31Å; D447-K451 PolarHBondContact O-N 3.25Å; E449-K451 PolarHBondContact O-N 3.1Å; K451-R455 WeakPolarHBondContact O-CB 3.32Å; K451-R455 WeakPolarHBondContact O-CG 3.49Å; K451-R455 PolarHBondContact O-N 2.78Å; K451-R455 VanDerWaalsContact O-N 3.11Å
452	R	77	Confident	70.4	Confident	159 Å²	159	129 Å²	129	60%	0.6	64%	0.638	S	S	*	*	H	α-helix	trans	-74.1	-34.8	175.9	-164.9	178.5	-175.6	-173	2.2	111.7	L448 E449 L450 R456	L448-R452 VanDerWaalsContact O-CB 3.31Å; L448-R452 WeakPolarHBondContact O-CB 3.37Å; L448-R452 PolarHBondContact O-N 3.39Å; E449-R452 CarbonylContact O-C 3.56Å; E449-R452 WeakPolarHBondContact O-CB 3.36Å; E449-R452 PolarHBondContact O-N 2.83Å; E449-R452 VanDerWaalsContact O-N 3.13Å; L450-R452 VanDerWaalsContact C-N 3.28Å; L450-R452 PolarHBondContact O-N 2.92Å; R452-R456 WeakPolarHBondContact O-CG 3.44Å; R452-R456 PolarHBondContact O-N 3.42Å; R452-R456 VanDerWaalsContact O-N 3.09Å
453	G	71.6	Confident	69.4	Low	29 Å²	29	128 Å²	128	30%	0.299	64%	0.641	S	S	.	*	H	α-helix	trans	-63.3	-50.6	171.3	0	0	0	0	0	111.8	E449 L450 R455 R456 D457	E449-G453 PolarHBondContact O-N 2.92Å; L450-G453 PolarHBondContact O-N 2.9Å; G453-R455 VanDerWaalsContact C-N 3.28Å; G453-R455 PolarHBondContact O-N 3.45Å; G453-R456 WeakPolarHBondContact O-CA 3.49Å; G453-R456 WeakPolarHBondContact O-CB 3.47Å; G453-R456 PolarHBondContact O-N 2.89Å; G453-D457 PolarHBondContact O-N 2.93Å
454	L	61.7	Low	68.3	Low	116 Å²	116	127.7 Å²	127.7	61%	0.607	64%	0.644	S	S	*	*	H	α-helix	trans	-59.2	-36.6	175.7	-72.5	163.2	0	0	0	112.9	L450 R456 G458	L450-L454 HydrophobicContact CD2-CD1 4.39Å; L450-L454 WeakPolarHBondContact O-CB 3.5Å; L450-L454 WeakPolarHBondContact O-CG 3.46Å; L450-L454 PolarHBondContact O-N 3.18Å; L454-R456 VanDerWaalsContact C-N 3.35Å; L454-G458 PolarHBondContact O-N 3.09Å
455	R	60.6	Low	67.1	Low	222 Å²	222	127.8 Å²	127.8	84%	0.838	65%	0.65	S	S	*	*	H	α-helix	trans	-70.8	-27.3	173.2	-77.1	-175.4	-173.9	-162	3	113.6	K451 G453	K451-R455 WeakPolarHBondContact O-CB 3.32Å; K451-R455 WeakPolarHBondContact O-CG 3.49Å; K451-R455 PolarHBondContact O-N 2.78Å; K451-R455 VanDerWaalsContact O-N 3.11Å; G453-R455 VanDerWaalsContact C-N 3.28Å; G453-R455 PolarHBondContact O-N 3.45Å
456	R	61	Low	65.8	Low	179 Å²	179	129.6 Å²	129.6	68%	0.675	66%	0.658	S	S	*	*	H	α-helix	trans	-81.8	-32.6	176.9	-81.4	178.9	173.1	173.8	-3.5	112.3	R452 G453 L454 G458	R452-R456 WeakPolarHBondContact O-CG 3.44Å; R452-R456 PolarHBondContact O-N 3.42Å; R452-R456 VanDerWaalsContact O-N 3.09Å; G453-R456 WeakPolarHBondContact O-CA 3.49Å; G453-R456 WeakPolarHBondContact O-CB 3.47Å; G453-R456 PolarHBondContact O-N 2.89Å; L454-R456 VanDerWaalsContact C-N 3.35Å; R456-G458 VanDerWaalsContact C-N 3.26Å; R456-G458 PolarHBondContact O-N 3.28Å
457	D	57.1	Low	64.4	Low	125 Å²	125	130.4 Å²	130.4	67%	0.668	67%	0.665	S	S	*	*	S	Bend	trans	-82.2	-1.9	179.4	-72.7	-19.7	0	0	0	113.8	G453 I459	G453-D457 PolarHBondContact O-N 2.93Å; D457-I459 PolarHBondContact O-N 3.11Å
458	G	50.3	Low	62.8	Low	55 Å²	55	132.9 Å²	132.9	57%	0.567	68%	0.676	S	S	*	*			trans	57.1	16.6	157.9	0	0	0	0	0	115.9	L454 R456 I460	L454-G458 PolarHBondContact O-N 3.09Å; R456-G458 VanDerWaalsContact C-N 3.26Å; R456-G458 PolarHBondContact O-N 3.28Å; G458-I460 PolarHBondContact O-N 2.8Å
459	I	47.4	Very low	61	Low	142 Å²	142	134.1 Å²	134.1	73%	0.728	68%	0.681	S	S	*	*			trans	-75.2	90.9	167.7	-46.7	-179.6	0	0	0	105.1	D457 P461	D457-I459 PolarHBondContact O-N 3.11Å; I459-P461 VanDerWaalsContact C-CD 3.44Å; I459-P461 HydrophobicContact CG2-CG 4.09Å; I459-P461 WeakPolarHBondContact O-CD 3.5Å
460	I	44.1	Very low	59.2	Low	157 Å²	157	133.8 Å²	133.8	81%	0.805	68%	0.684	S	S	*	*			trans	-86.9	97.6	153	-57.2	172.2	0	0	0	104.7	G458	G458-I460 PolarHBondContact O-N 2.8Å
461	P	45	Very low	57.5	Low	98 Å²	98	135 Å²	135	64%	0.636	69%	0.689	S	S	*	*			trans	-86.9	126.9	155.3	30.9	-18	0	0	0	107.6	I459	I459-P461 VanDerWaalsContact C-CD 3.44Å; I459-P461 HydrophobicContact CG2-CG 4.09Å; I459-P461 WeakPolarHBondContact O-CD 3.5Å
462	T	36.7	Very low	55.7	Low	207 Å²	207	135.4 Å²	135.4	100%	1.27	70%	0.7	S	S	*	*			trans	-46.7	0	156.9	45.5	0	0	0	0	112.8

Retrieved 462 of 462 residues in 255.7 ms (Link to these results)

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